# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Fun_ATP-synt_8 PF05933.8 KFH40209.1 - 4.2e-22 77.9 11.3 4.5e-22 77.8 7.8 1.0 1 0 0 1 1 1 1 Fungal ATP synthase protein 8 (A6L) PTS_EIIC_2 PF13303.1 KFH40209.1 - 0.13 11.1 1.6 0.12 11.1 1.1 1.0 1 0 0 1 1 1 0 Phosphotransferase system, EIIC YMF19 PF02326.10 KFH40209.1 - 0.15 12.6 4.2 0.17 12.4 2.9 1.0 1 0 0 1 1 1 0 Plant ATP synthase F0 RIC3 PF15361.1 KFH40209.1 - 0.49 10.6 1.6 0.5 10.5 1.1 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 ATP-synt_A PF00119.15 KFH40210.1 - 1.1e-44 152.4 23.9 1.3e-44 152.3 16.5 1.0 1 0 0 1 1 1 1 ATP synthase A chain NIT PF08376.5 KFH40211.1 - 0.023 14.2 0.6 0.036 13.5 0.4 1.2 1 0 0 1 1 1 0 Nitrate and nitrite sensing Vps16_N PF04841.8 KFH40211.1 - 0.032 12.7 0.1 0.04 12.4 0.0 1.1 1 0 0 1 1 1 0 Vps16, N-terminal region Zn_ribbon_2 PF12674.2 KFH40211.1 - 0.043 14.1 0.1 0.07 13.4 0.0 1.5 1 0 0 1 1 1 0 Putative zinc ribbon domain SbcD_C PF12320.3 KFH40211.1 - 0.14 12.2 1.3 0.24 11.4 0.9 1.4 1 0 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain Chlam_OMP6 PF03504.8 KFH40211.1 - 0.14 12.4 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 6 Seryl_tRNA_N PF02403.17 KFH40211.1 - 0.78 9.7 6.0 2.2 8.3 2.8 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain bZIP_Maf PF03131.12 KFH40211.1 - 2.2 8.6 6.2 0.65 10.3 0.8 2.4 2 1 1 3 3 3 0 bZIP Maf transcription factor Evr1_Alr PF04777.8 KFH40213.1 - 9e-30 102.4 1.8 2.8e-29 100.8 0.1 2.0 2 0 0 2 2 2 1 Erv1 / Alr family IBR PF01485.16 KFH40215.1 - 5.8e-13 48.5 14.3 5.4e-12 45.4 3.5 3.7 3 1 0 3 3 3 2 IBR domain TRP PF06011.7 KFH40216.1 - 5.4e-85 285.5 25.9 5.4e-85 285.5 17.9 2.1 2 1 0 2 2 2 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KFH40216.1 - 1.1e-19 70.8 0.0 1.8e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 ML-like domain Anoctamin PF04547.7 KFH40217.1 - 3.2e-119 398.5 10.8 3.9e-119 398.2 7.5 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Glyoxalase_2 PF12681.2 KFH40218.1 - 2.5e-14 53.7 0.7 4.7e-14 52.9 0.2 1.6 1 1 1 2 2 2 2 Glyoxalase-like domain Glyoxalase PF00903.20 KFH40218.1 - 3.7e-10 39.8 0.0 6.3e-10 39.1 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KFH40218.1 - 5.2e-10 39.3 0.0 6.9e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 KFH40218.1 - 0.00038 20.4 0.2 0.0029 17.5 0.1 1.9 1 1 0 1 1 1 1 Glyoxalase-like domain Conotoxin PF02950.12 KFH40220.1 - 0.033 14.9 3.1 0.043 14.6 2.2 1.2 1 0 0 1 1 1 0 Conotoxin DUF1752 PF08550.5 KFH40223.1 - 1e-05 25.0 1.4 1e-05 25.0 1.0 2.0 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) Cytochrom_B561 PF03188.11 KFH40224.1 - 9.4e-16 57.8 2.0 9.4e-16 57.8 1.4 1.6 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 PepSY_TM_1 PF13172.1 KFH40224.1 - 0.0066 16.1 0.5 0.0066 16.1 0.3 4.4 5 0 0 5 5 5 1 PepSY-associated TM helix Glyco_trans_4_2 PF13477.1 KFH40224.1 - 0.12 12.2 0.2 0.19 11.5 0.2 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like DUF2868 PF11067.3 KFH40224.1 - 0.12 11.4 1.6 0.25 10.4 1.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2868) DUF4079 PF13301.1 KFH40224.1 - 0.25 11.3 15.4 0.15 12.0 1.6 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF4079) COX15-CtaA PF02628.10 KFH40224.1 - 0.79 8.5 15.5 34 3.1 10.5 2.5 1 1 0 1 1 1 0 Cytochrome oxidase assembly protein Cytochrom_B_N PF00033.14 KFH40224.1 - 1.4 8.2 16.5 1.3e+02 1.8 10.7 3.1 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB DUF4006 PF13179.1 KFH40224.1 - 6.4 6.4 11.3 7.5 6.1 0.3 3.6 4 0 0 4 4 4 0 Family of unknown function (DUF4006) Coiled-coil_56 PF09813.4 KFH40225.1 - 0.056 13.4 0.0 0.062 13.2 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 ATG16 PF08614.6 KFH40227.1 - 2.3e-43 148.3 17.8 2.6e-43 148.1 12.3 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Filament PF00038.16 KFH40227.1 - 0.00011 21.8 13.2 0.00039 19.9 8.0 1.8 1 1 1 2 2 2 1 Intermediate filament protein CCDC144C PF14915.1 KFH40227.1 - 0.0015 17.5 14.0 0.1 11.5 7.5 2.0 1 1 1 2 2 2 2 CCDC144C protein coiled-coil region PaaA_PaaC PF05138.7 KFH40227.1 - 0.0054 15.7 2.1 0.036 13.0 0.1 2.1 2 0 0 2 2 2 1 Phenylacetic acid catabolic protein Myosin_tail_1 PF01576.14 KFH40227.1 - 0.016 12.9 20.6 0.013 13.2 13.1 1.6 1 1 0 1 1 1 0 Myosin tail TPR_19 PF14559.1 KFH40227.1 - 0.02 15.2 1.5 0.05 13.9 1.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat APG6 PF04111.7 KFH40227.1 - 0.046 12.7 15.9 0.041 12.9 8.1 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 SPX PF03105.14 KFH40227.1 - 0.047 13.4 3.4 0.053 13.2 2.4 1.3 1 0 0 1 1 1 0 SPX domain V_ATPase_I PF01496.14 KFH40227.1 - 0.076 10.8 6.9 0.11 10.3 4.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-F_leu_zip PF10473.4 KFH40227.1 - 0.29 10.9 15.6 0.08 12.7 7.5 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4201 PF13870.1 KFH40227.1 - 0.44 9.9 16.3 0.24 10.8 8.8 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) Spc7 PF08317.6 KFH40227.1 - 0.52 8.9 15.6 0.59 8.7 8.5 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Reo_sigmaC PF04582.7 KFH40227.1 - 0.59 9.2 2.1 2.9 6.9 1.4 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 KFH40227.1 - 1.4 7.2 9.0 2.6 6.4 6.3 1.5 1 1 0 1 1 1 0 AAA domain TMF_DNA_bd PF12329.3 KFH40227.1 - 1.4 8.7 17.8 0.85 9.4 2.7 3.7 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4140 PF13600.1 KFH40227.1 - 3.4 8.1 19.0 3.9 7.9 0.1 3.4 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) GAS PF13851.1 KFH40227.1 - 3.7 6.6 16.7 6.1 5.9 10.0 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding zf-C4H2 PF10146.4 KFH40227.1 - 4.4 7.2 10.8 3.1 7.7 6.3 1.6 1 1 0 1 1 1 0 Zinc finger-containing protein Atg14 PF10186.4 KFH40227.1 - 5.7 5.7 13.8 9.6 5.0 9.6 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Vps16_N PF04841.8 KFH40228.1 - 1.7e-80 270.6 0.0 2.2e-80 270.2 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 KFH40228.1 - 2e-74 250.4 0.0 2.8e-74 249.9 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region WD40 PF00400.27 KFH40228.1 - 0.094 12.6 0.2 2 8.4 0.0 3.0 3 0 0 3 3 3 0 WD domain, G-beta repeat DOT1 PF08123.8 KFH40229.1 - 2.6e-70 235.9 0.0 5.5e-70 234.8 0.0 1.5 2 0 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 KFH40229.1 - 0.0018 18.8 0.7 0.029 14.9 0.1 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFH40229.1 - 0.0022 17.9 0.1 0.0058 16.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH40229.1 - 0.013 15.1 0.1 0.025 14.1 0.1 1.4 1 1 0 1 1 1 0 Methyltransferase domain DUF2194 PF09960.4 KFH40229.1 - 0.11 10.5 0.0 0.15 10.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2194) Mito_carr PF00153.22 KFH40230.1 - 5.2e-54 179.9 0.1 1.1e-19 69.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L22e PF01776.12 KFH40231.1 - 2e-46 156.6 1.2 2.4e-46 156.3 0.8 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF2841 PF11001.3 KFH40233.1 - 6.3e-39 132.6 4.1 1.2e-38 131.8 2.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) MFS_1 PF07690.11 KFH40234.1 - 8.4e-16 57.6 12.3 1.2e-15 57.1 8.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH40234.1 - 1.3e-12 47.0 0.2 1.3e-12 47.0 0.1 2.2 2 1 1 3 3 3 1 Sugar (and other) transporter YrhK PF14145.1 KFH40234.1 - 0.0055 16.3 2.9 0.012 15.2 0.2 2.8 2 0 0 2 2 2 1 YrhK-like protein MTHFR PF02219.12 KFH40236.1 - 6.4e-102 340.5 0.0 9e-102 340.0 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase GATase_5 PF13507.1 KFH40237.1 - 8.9e-91 303.3 0.0 1.4e-90 302.7 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 KFH40237.1 - 5.5e-38 130.3 0.7 3.6e-21 75.7 0.1 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 KFH40237.1 - 8.2e-25 86.8 0.1 1.7e-23 82.6 0.0 3.1 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain Pkinase PF00069.20 KFH40238.1 - 2.7e-26 92.2 0.0 1.3e-12 47.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFH40238.1 - 2.9e-06 26.5 0.0 0.0042 16.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Crp PF00325.15 KFH40238.1 - 0.0098 15.3 0.7 0.43 10.1 0.1 2.9 3 0 0 3 3 3 1 Bacterial regulatory proteins, crp family Serpulina_VSP PF05540.6 KFH40238.1 - 0.21 10.3 0.0 0.3 9.8 0.0 1.1 1 0 0 1 1 1 0 Serpulina hyodysenteriae variable surface protein YrhK PF14145.1 KFH40239.1 - 2.5e-06 27.0 19.8 1.9e-05 24.2 0.8 4.8 3 2 2 5 5 5 3 YrhK-like protein DUF2855 PF11017.3 KFH40240.1 - 2e-51 175.0 0.0 2.4e-51 174.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) SAM_2 PF07647.12 KFH40241.1 - 7.5e-17 60.9 0.0 2.1e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFH40241.1 - 4.6e-16 58.7 0.0 9e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 KFH40241.1 - 2e-15 57.0 0.0 4.1e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Fungal_trans PF04082.13 KFH40242.1 - 0.00026 19.9 0.0 0.00036 19.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tropomyosin PF00261.15 KFH40242.1 - 0.12 11.4 0.4 0.18 10.8 0.2 1.2 1 0 0 1 1 1 0 Tropomyosin p450 PF00067.17 KFH40243.1 - 6e-05 21.7 0.1 6.9e-05 21.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 FLO_LFY PF01698.11 KFH40243.1 - 0.029 13.2 0.0 0.034 12.9 0.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Rubrerythrin PF02915.12 KFH40243.1 - 0.039 14.2 0.1 0.054 13.8 0.0 1.3 1 0 0 1 1 1 0 Rubrerythrin Myosin_TH1 PF06017.8 KFH40243.1 - 0.063 12.5 0.1 0.082 12.2 0.1 1.2 1 0 0 1 1 1 0 Myosin tail HNF_C PF09354.5 KFH40243.1 - 0.07 14.2 0.0 0.12 13.4 0.0 1.5 1 0 0 1 1 1 0 HNF3 C-terminal domain DUF1446 PF07287.6 KFH40244.1 - 8e-123 409.4 0.1 9.5e-123 409.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) Oxidored_molyb PF00174.14 KFH40246.1 - 7.1e-56 188.2 0.0 1.1e-55 187.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 KFH40246.1 - 6.3e-28 97.0 0.7 4.7e-27 94.1 0.5 2.2 1 1 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.23 KFH40246.1 - 9.4e-15 54.1 0.3 1.5e-14 53.4 0.2 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3506 PF12014.3 KFH40247.1 - 2.9e-44 150.1 0.0 2.4e-43 147.1 0.0 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 KFH40247.1 - 9.8e-08 31.6 0.5 9.8e-08 31.6 0.3 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KFH40247.1 - 6.3e-06 25.7 0.3 2.6e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 F-box domain zf-met PF12874.2 KFH40249.1 - 0.02 15.1 3.7 0.84 9.9 0.5 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 KFH40249.1 - 0.057 13.7 1.1 0.057 13.7 0.7 3.4 2 1 1 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFH40249.1 - 0.36 11.2 21.0 0.22 11.9 1.2 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger Pex16 PF08610.5 KFH40250.1 - 7.7e-107 357.1 0.0 8.8e-107 356.9 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) DUF3317 PF11779.3 KFH40251.1 - 3.9e-16 58.2 3.1 5e-16 57.8 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) Ion_trans_N PF08412.5 KFH40251.1 - 0.14 11.4 0.7 0.21 10.9 0.5 1.3 1 0 0 1 1 1 0 Ion transport protein N-terminal Actin PF00022.14 KFH40253.1 - 2.9e-159 529.7 0.0 3.3e-159 529.5 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 KFH40253.1 - 0.039 14.3 0.0 0.12 12.8 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Ribosomal_L5_C PF00673.16 KFH40254.1 - 1.3e-23 82.5 0.0 2.1e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 KFH40254.1 - 0.00052 19.7 0.2 0.00093 18.9 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 RF-1 PF00472.15 KFH40255.1 - 4.7e-26 90.8 2.2 8.8e-26 89.9 1.5 1.4 1 0 0 1 1 1 1 RF-1 domain DUF4626 PF15422.1 KFH40255.1 - 0.012 15.6 1.8 0.019 14.8 1.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4626) MIR PF02815.14 KFH40255.1 - 0.03 13.8 0.1 0.08 12.4 0.0 1.7 1 1 1 2 2 2 0 MIR domain Hairpins PF04877.7 KFH40255.1 - 0.081 12.3 0.8 0.1 12.0 0.6 1.1 1 0 0 1 1 1 0 HrpZ Fes1 PF08609.5 KFH40256.1 - 2.5e-31 108.0 2.7 2.5e-31 108.0 1.9 2.0 3 0 0 3 3 3 1 Nucleotide exchange factor Fes1 Arm PF00514.18 KFH40256.1 - 1.3e-06 28.0 0.0 0.13 12.1 0.0 3.2 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFH40256.1 - 3.6e-06 27.1 0.3 1.5e-05 25.1 0.0 2.2 3 1 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.1 KFH40256.1 - 6.4e-05 23.3 0.1 0.071 13.6 0.0 3.2 4 0 0 4 4 4 2 HEAT-like repeat HEAT PF02985.17 KFH40256.1 - 0.00063 19.6 0.0 0.097 12.8 0.0 2.8 2 0 0 2 2 2 1 HEAT repeat V-ATPase_H_C PF11698.3 KFH40256.1 - 0.073 12.9 0.3 0.53 10.2 0.1 2.3 1 1 1 2 2 2 0 V-ATPase subunit H DUF1771 PF08590.5 KFH40256.1 - 0.074 13.0 0.3 0.16 11.9 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) E1-E2_ATPase PF00122.15 KFH40258.1 - 5e-63 212.2 2.3 9e-63 211.3 1.6 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFH40258.1 - 7.3e-30 103.8 9.2 7.3e-30 103.8 6.4 2.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFH40258.1 - 1.3e-28 100.9 0.0 1.6e-27 97.3 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFH40258.1 - 5.4e-15 55.1 0.0 2.2e-14 53.1 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KFH40258.1 - 1.2e-14 53.4 0.5 5.3e-14 51.4 0.0 2.4 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KFH40258.1 - 9e-13 48.8 0.0 2.5e-12 47.3 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFH40258.1 - 0.00033 20.3 0.3 0.00056 19.5 0.2 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Porin_3 PF01459.17 KFH40259.1 - 1.1e-81 274.1 0.1 1.3e-81 273.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin 6PF2K PF01591.13 KFH40260.1 - 3.7e-58 196.2 0.0 5.4e-58 195.6 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KFH40260.1 - 2.8e-24 86.0 0.6 4.3e-24 85.3 0.4 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 KFH40260.1 - 9.6e-05 23.1 0.0 0.0034 18.2 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 KFH40260.1 - 0.0039 17.0 0.0 0.009 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KFH40260.1 - 0.015 14.5 0.0 0.036 13.2 0.0 1.6 1 1 0 1 1 1 0 Chromatin associated protein KTI12 IstB_IS21 PF01695.12 KFH40260.1 - 0.042 13.2 0.0 0.082 12.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein UCH_1 PF13423.1 KFH40261.1 - 2.8e-73 246.9 0.0 9e-73 245.2 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Herpes_TAF50 PF03326.8 KFH40263.1 - 0.15 11.0 4.7 0.16 10.9 3.3 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) CDC27 PF09507.5 KFH40263.1 - 0.29 10.2 15.5 0.33 10.1 10.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 BUD22 PF09073.5 KFH40263.1 - 3.6 6.5 25.0 4.5 6.2 17.3 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 KFH40263.1 - 9.4 4.0 30.6 11 3.7 21.2 1.1 1 0 0 1 1 1 0 Nop14-like family CRC_subunit PF08624.5 KFH40264.1 - 1.8e-54 183.4 0.0 2.4e-54 183.0 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Rad4 PF03835.10 KFH40266.1 - 2e-31 108.3 0.4 4.1e-31 107.3 0.3 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 KFH40266.1 - 4.4e-28 96.7 0.0 8.8e-28 95.8 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 KFH40266.1 - 1.4e-21 75.7 0.0 3.3e-21 74.5 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 KFH40266.1 - 8.1e-11 42.0 1.2 1.9e-10 40.8 0.0 2.4 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 KFH40266.1 - 0.0021 18.2 2.1 0.0089 16.2 0.6 2.6 2 1 0 2 2 2 1 Transglutaminase-like superfamily DUF3357 PF11837.3 KFH40268.1 - 0.051 13.4 2.6 1 9.2 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) Glyco_transf_64 PF09258.5 KFH40270.1 - 4.7e-56 189.7 0.0 6.2e-56 189.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_transf_21 PF13506.1 KFH40270.1 - 0.041 13.1 0.0 0.066 12.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 21 TPT PF03151.11 KFH40271.1 - 2.4e-19 69.4 15.1 2.4e-19 69.4 10.5 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KFH40271.1 - 2.5e-05 24.3 10.2 2.5e-05 24.3 7.1 2.5 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 KFH40271.1 - 0.00063 18.7 18.7 0.013 14.4 13.0 2.1 1 1 0 1 1 1 1 UAA transporter family Cupin_2 PF07883.6 KFH40273.1 - 1.5e-08 34.0 0.0 3.2e-08 32.9 0.0 1.6 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.7 KFH40273.1 - 0.00012 21.3 0.0 0.0002 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) ARD PF03079.9 KFH40273.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 ARD/ARD' family DUF1769 PF08588.5 KFH40274.1 - 2.1e-27 94.8 0.2 4e-27 93.9 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Abhydrolase_6 PF12697.2 KFH40275.1 - 2.7e-15 56.9 3.9 4.9e-15 56.0 2.7 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFH40275.1 - 1.2e-05 25.0 0.1 0.00011 21.8 0.0 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFH40275.1 - 1.2e-05 25.0 0.1 2.2e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 KFH40275.1 - 0.024 14.1 0.0 0.054 12.9 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase Gly_transf_sug PF04488.10 KFH40276.1 - 5.8e-10 39.4 0.0 1.7e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Peptidase_M20 PF01546.23 KFH40277.1 - 1.5e-27 96.2 0.0 2.1e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.12 KFH40277.1 - 4.9e-05 23.1 0.0 0.00012 21.8 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 M20_dimer PF07687.9 KFH40277.1 - 0.00028 20.5 0.1 0.00081 19.1 0.1 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain Acyl_transf_3 PF01757.17 KFH40278.1 - 5e-31 107.7 36.3 6e-31 107.5 25.2 1.1 1 0 0 1 1 1 1 Acyltransferase family ABC_tran PF00005.22 KFH40279.1 - 3.3e-20 72.7 0.0 6.4e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KFH40279.1 - 2e-09 37.2 4.9 3.7e-09 36.4 3.4 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF258 PF03193.11 KFH40279.1 - 0.00024 20.3 0.0 0.00045 19.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 KFH40279.1 - 0.0032 18.2 0.0 0.0095 16.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFH40279.1 - 0.0058 15.7 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.1 KFH40279.1 - 0.02 14.3 0.1 0.052 13.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 KFH40279.1 - 0.025 14.5 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KFH40279.1 - 0.042 13.8 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.1 KFH40279.1 - 0.071 12.5 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ice_nucleation PF00818.12 KFH40279.1 - 0.19 11.1 5.2 0.39 10.1 3.6 1.6 1 0 0 1 1 1 0 Ice nucleation protein repeat RINGv PF12906.2 KFH40280.1 - 6.9e-05 22.8 7.5 0.00012 22.0 5.2 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 KFH40280.1 - 0.0071 16.1 10.0 0.016 14.9 6.9 1.6 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 KFH40280.1 - 0.12 12.3 5.5 0.23 11.4 3.8 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-rbx1 PF12678.2 KFH40280.1 - 0.26 11.4 3.9 0.51 10.4 2.7 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger DUF605 PF04652.11 KFH40280.1 - 0.32 10.3 2.6 0.43 9.9 1.8 1.2 1 0 0 1 1 1 0 Vta1 like CENP-T PF15511.1 KFH40280.1 - 0.88 8.7 14.3 1.3 8.1 9.9 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T zf-RING_4 PF14570.1 KFH40280.1 - 1.8 8.2 8.7 3.5 7.3 6.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 KFH40280.1 - 4.7 6.9 7.4 8.8 6.0 5.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) bZIP_1 PF00170.16 KFH40281.1 - 1e-09 38.1 5.1 1e-09 38.1 3.6 1.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KFH40281.1 - 7.2e-05 22.5 5.8 0.00018 21.2 4.0 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFH40281.1 - 0.0088 16.3 6.6 0.0088 16.3 4.5 2.1 2 1 1 3 3 3 1 bZIP Maf transcription factor CCDC155 PF14662.1 KFH40281.1 - 0.058 12.9 0.3 0.09 12.3 0.2 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 PAT1 PF09770.4 KFH40281.1 - 1.2 7.3 8.9 1.5 6.9 6.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDC45 PF02724.9 KFH40281.1 - 3.5 5.5 6.7 4.7 5.1 4.6 1.1 1 0 0 1 1 1 0 CDC45-like protein PGK PF00162.14 KFH40282.1 - 4.3e-152 506.1 0.5 5.5e-152 505.7 0.3 1.1 1 0 0 1 1 1 1 Phosphoglycerate kinase TPR_11 PF13414.1 KFH40282.1 - 2e-17 62.6 14.6 4.6e-15 55.0 4.9 3.3 2 1 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 KFH40282.1 - 1.4e-13 49.7 12.2 1.5e-07 30.7 0.4 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFH40282.1 - 2.8e-13 48.6 15.9 2.5e-06 26.9 0.3 4.9 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFH40282.1 - 6.1e-08 33.1 16.0 1.9e-07 31.5 5.9 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFH40282.1 - 2.5e-07 30.3 6.6 0.0054 16.8 0.4 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFH40282.1 - 1.7e-05 25.0 14.1 0.019 15.5 0.2 4.1 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFH40282.1 - 2.2e-05 23.9 2.3 0.11 12.3 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFH40282.1 - 0.00082 19.6 6.3 0.0056 16.9 2.3 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFH40282.1 - 0.0036 17.2 12.2 0.036 14.0 0.5 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.12 KFH40282.1 - 0.0045 17.2 6.2 0.061 13.6 1.1 2.4 1 1 1 2 2 2 1 Bacterial transcriptional activator domain PrpR_N PF06506.6 KFH40282.1 - 0.042 13.2 0.6 1.9 7.8 0.1 3.2 3 0 0 3 3 3 0 Propionate catabolism activator TPR_9 PF13371.1 KFH40282.1 - 0.053 13.3 5.6 0.11 12.3 1.1 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat XPC-binding PF09280.6 KFH40282.1 - 0.058 12.8 6.0 0.055 12.9 2.6 2.1 2 0 0 2 2 2 0 XPC-binding domain TPR_8 PF13181.1 KFH40282.1 - 0.57 10.0 11.1 4.2 7.3 0.0 4.5 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFH40282.1 - 1.5 9.4 7.8 8.4 7.0 0.6 3.6 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 KFH40282.1 - 1.8 8.6 4.6 2.1 8.3 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat FIVAR PF07554.8 KFH40282.1 - 3.8 7.8 7.5 4.2 7.7 0.0 3.9 4 0 0 4 4 4 0 Uncharacterised Sugar-binding Domain Apc3 PF12895.2 KFH40282.1 - 7.4 6.7 6.9 13 5.9 1.2 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Mito_fiss_reg PF05308.6 KFH40286.1 - 9.5 5.5 11.7 0.32 10.3 1.2 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator Brr6_like_C_C PF10104.4 KFH40287.1 - 8.6e-27 93.2 0.0 1.2e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Fungal_trans PF04082.13 KFH40289.1 - 3.4e-23 81.8 1.4 3.7e-23 81.7 0.3 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH40289.1 - 1.3e-07 31.3 11.9 2.4e-07 30.5 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Period_C PF12114.3 KFH40289.1 - 0.15 11.6 4.1 0.26 10.8 2.9 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Macoilin PF09726.4 KFH40289.1 - 6.8 4.8 7.1 9 4.4 4.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Med26 PF08711.6 KFH40290.1 - 3.6e-12 45.5 0.0 6.4e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Pkinase PF00069.20 KFH40291.1 - 4.7e-43 147.2 0.4 5.4e-25 88.0 0.2 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFH40291.1 - 5.5e-15 55.1 0.2 2.2e-10 40.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase HRXXH PF13933.1 KFH40294.1 - 1.3e-102 342.4 0.0 1.5e-102 342.2 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Peptidase_M35 PF02102.10 KFH40294.1 - 0.00016 20.4 0.0 0.00026 19.7 0.0 1.2 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family HCV_NS5a_1a PF08300.8 KFH40294.1 - 0.18 11.7 1.8 0.33 10.9 0.3 2.0 1 1 1 2 2 2 0 Hepatitis C virus non-structural 5a zinc finger domain Peptidase_M28 PF04389.12 KFH40295.1 - 2e-36 125.3 0.0 2.7e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 CDP-OH_P_transf PF01066.16 KFH40296.1 - 5.1e-18 65.2 1.7 5.1e-18 65.2 1.2 2.3 3 0 0 3 3 3 1 CDP-alcohol phosphatidyltransferase DPBB_1 PF03330.13 KFH40297.1 - 0.00059 19.7 0.1 0.00091 19.1 0.1 1.5 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KFH40297.1 - 0.04 13.6 0.1 0.052 13.2 0.1 1.3 1 0 0 1 1 1 0 Barwin family Methyltransf_2 PF00891.13 KFH40298.1 - 1.1e-25 90.1 0.2 1.9e-25 89.4 0.1 1.4 1 0 0 1 1 1 1 O-methyltransferase MarR PF01047.17 KFH40298.1 - 0.021 14.5 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 MarR family Methyltransf_18 PF12847.2 KFH40298.1 - 0.025 15.1 0.0 0.057 14.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain SPOUT_MTase PF02590.12 KFH40298.1 - 0.031 14.0 0.4 0.28 10.8 0.0 2.5 3 0 0 3 3 3 0 Predicted SPOUT methyltransferase Methyltransf_25 PF13649.1 KFH40298.1 - 0.034 14.5 0.1 0.15 12.4 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.1 KFH40298.1 - 0.083 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KFH40298.1 - 0.12 11.7 0.0 0.63 9.4 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain Peptidase_S8 PF00082.17 KFH40299.1 - 1.6e-46 158.7 0.0 2.8e-46 157.9 0.0 1.4 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 KFH40299.1 - 1.7e-12 47.7 0.0 3.6e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 KFH40299.1 - 8.3e-12 44.6 0.5 2.4e-11 43.2 0.0 2.0 2 0 0 2 2 2 1 PA domain FlgD_ig PF13860.1 KFH40299.1 - 0.0075 15.9 0.0 0.027 14.2 0.0 1.9 1 0 0 1 1 1 1 FlgD Ig-like domain FAD_binding_4 PF01565.18 KFH40300.1 - 6.8e-19 67.7 2.8 4.9e-18 64.9 0.3 2.9 3 0 0 3 3 3 1 FAD binding domain BBE PF08031.7 KFH40300.1 - 3.4e-05 23.6 0.0 8.3e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like DPBB_1 PF03330.13 KFH40301.1 - 6.9e-07 29.1 0.1 1.2e-06 28.3 0.1 1.5 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KFH40301.1 - 0.027 14.1 0.2 0.033 13.8 0.1 1.2 1 0 0 1 1 1 0 Barwin family MFS_1 PF07690.11 KFH40302.1 - 5.2e-36 124.0 24.4 1.2e-35 122.8 17.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2243 PF10002.4 KFH40302.1 - 0.1 12.3 2.0 3.2 7.5 0.0 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2243) Acetyltransf_3 PF13302.1 KFH40303.1 - 6.1e-14 52.3 0.0 8e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KFH40303.1 - 0.00012 22.0 0.0 0.00018 21.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFH40303.1 - 0.02 14.9 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 KFH40303.1 - 0.027 14.3 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain OB_NTP_bind PF07717.11 KFH40304.1 - 1.1e-25 89.6 0.0 3.7e-25 87.9 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KFH40304.1 - 2e-23 82.3 0.0 4.7e-23 81.1 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KFH40304.1 - 6.2e-11 42.0 0.0 1.3e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFH40304.1 - 1e-06 28.3 0.2 4.5e-06 26.2 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KFH40304.1 - 1.9e-05 24.7 0.0 5.4e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KFH40304.1 - 0.00018 20.4 0.0 0.0004 19.3 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.17 KFH40304.1 - 0.00072 19.0 0.1 0.0022 17.4 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.10 KFH40304.1 - 0.012 15.4 0.1 2.6 7.8 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Response_reg PF00072.19 KFH40304.1 - 0.085 12.8 0.4 0.33 10.9 0.1 2.1 2 0 0 2 2 2 0 Response regulator receiver domain Aminotran_5 PF00266.14 KFH40305.1 - 2.1e-26 92.5 0.0 2.7e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 KFH40305.1 - 0.0019 18.0 0.1 0.056 13.3 0.0 2.3 2 0 0 2 2 2 1 B12 binding domain PRMT5 PF05185.11 KFH40306.1 - 9.6e-166 552.1 0.0 1.2e-165 551.8 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase CBM_1 PF00734.13 KFH40307.1 - 9.5e-14 50.7 16.8 2.6e-13 49.3 11.7 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Abhydrolase_2 PF02230.11 KFH40307.1 - 8.6e-08 31.8 0.0 1.4e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KFH40307.1 - 6.3e-06 25.9 0.1 1.2e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFH40307.1 - 1.7e-05 24.1 1.0 9.5e-05 21.7 0.2 2.2 3 0 0 3 3 3 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 KFH40307.1 - 0.00027 20.2 0.3 0.00045 19.5 0.2 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.2 KFH40307.1 - 0.0024 17.7 0.4 0.0038 17.1 0.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KFH40307.1 - 0.024 14.0 0.5 0.05 13.0 0.3 1.6 1 1 0 1 1 1 0 Putative esterase DLH PF01738.13 KFH40307.1 - 0.1 11.8 0.1 0.15 11.3 0.1 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Nucleoplasmin PF03066.10 KFH40307.1 - 0.21 11.0 1.2 0.29 10.6 0.9 1.2 1 0 0 1 1 1 0 Nucleoplasmin Toxin_7 PF05980.7 KFH40307.1 - 0.25 11.3 10.1 0.58 10.2 7.0 1.7 1 0 0 1 1 1 0 Toxin 7 HET PF06985.6 KFH40309.1 - 1.3e-15 57.8 0.0 3.1e-15 56.5 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) WTF PF03303.8 KFH40310.1 - 0.089 12.1 0.0 0.1 11.9 0.0 1.0 1 0 0 1 1 1 0 WTF protein dCMP_cyt_deam_1 PF00383.17 KFH40311.1 - 8.1e-07 28.6 0.0 2.7e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region 6PF2K PF01591.13 KFH40312.1 - 8.3e-70 234.3 0.0 2.6e-50 170.5 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KFH40312.1 - 1e-19 71.1 1.4 1.8e-18 67.1 0.0 3.2 2 2 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KFH40312.1 - 2.5e-06 27.4 0.0 2.1e-05 24.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KFH40312.1 - 0.0081 16.9 1.1 0.048 14.4 0.0 2.9 2 2 0 3 3 3 1 AAA domain KTI12 PF08433.5 KFH40312.1 - 0.015 14.4 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 KFH40312.1 - 0.074 12.1 0.0 0.93 8.5 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin PhoU PF01895.14 KFH40312.1 - 0.3 11.5 1.6 0.55 10.7 0.2 2.2 2 1 0 2 2 2 0 PhoU domain RNA_pol_A_bac PF01000.21 KFH40313.1 - 1e-32 112.5 0.0 1.7e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KFH40313.1 - 5.4e-15 54.2 0.0 7.1e-15 53.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain tRNA-synt_2d PF01409.15 KFH40314.1 - 4e-47 160.5 0.0 1.7e-24 86.3 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 KFH40314.1 - 2.7e-24 85.1 0.0 6.1e-24 84.0 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain WD40 PF00400.27 KFH40316.1 - 7.1e-41 136.6 7.7 9e-09 34.8 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat Sof1 PF04158.9 KFH40316.1 - 5.5e-31 106.4 15.7 1.3e-30 105.2 10.9 1.7 1 0 0 1 1 1 1 Sof1-like domain eIF2A PF08662.6 KFH40316.1 - 4e-05 23.4 1.8 0.0051 16.5 0.1 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 KFH40316.1 - 0.00014 20.2 0.7 0.017 13.4 0.1 2.4 1 1 1 2 2 2 2 Cytochrome D1 heme domain Mito_carr PF00153.22 KFH40317.1 - 4.8e-53 176.8 0.1 3e-19 68.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein GN3L_Grn1 PF08701.6 KFH40318.1 - 7.3e-25 86.6 18.0 1.4e-24 85.7 12.5 1.5 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 KFH40318.1 - 3.5e-20 72.1 0.0 2e-14 53.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFH40318.1 - 7.2e-07 28.8 0.0 0.025 14.0 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KFH40318.1 - 8.5e-07 28.9 5.3 0.064 13.0 0.0 4.1 3 1 1 4 4 4 2 Dynamin family DUF258 PF03193.11 KFH40318.1 - 5e-05 22.5 0.2 8.7e-05 21.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ORC3_N PF07034.6 KFH40318.1 - 0.003 16.5 0.0 0.0054 15.7 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus FeoB_N PF02421.13 KFH40318.1 - 0.0033 16.7 0.1 0.071 12.3 0.0 2.5 2 1 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 KFH40318.1 - 0.0067 16.9 0.4 1.5 9.3 0.1 2.7 2 0 0 2 2 2 1 Miro-like protein ArgK PF03308.11 KFH40318.1 - 0.019 13.7 0.1 0.019 13.7 0.1 2.7 3 0 0 3 3 3 0 ArgK protein AAA_16 PF13191.1 KFH40318.1 - 0.049 13.6 2.6 0.064 13.2 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain WH2 PF02205.15 KFH40318.1 - 0.1 12.2 3.0 2 8.1 1.0 2.7 2 0 0 2 2 2 0 WH2 motif AAA_18 PF13238.1 KFH40318.1 - 0.51 10.6 3.8 2 8.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain Pkinase PF00069.20 KFH40319.1 - 1.1e-55 188.6 0.2 1.2e-39 136.0 0.2 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFH40319.1 - 8.7e-27 93.8 0.2 7.6e-21 74.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KFH40319.1 - 0.00012 21.1 0.0 0.00024 20.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFH40319.1 - 0.00015 20.9 0.1 0.0012 17.9 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFH40319.1 - 0.00015 21.5 1.5 0.017 14.8 0.1 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFH40319.1 - 0.041 12.6 0.1 0.062 12.0 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 KFH40319.1 - 0.072 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_C PF00433.19 KFH40319.1 - 0.22 12.0 0.2 0.22 12.0 0.2 2.2 2 0 0 2 2 2 0 Protein kinase C terminal domain RIO1 PF01163.17 KFH40319.1 - 0.26 10.6 2.5 0.37 10.1 0.0 2.1 2 0 0 2 2 2 0 RIO1 family BAF1_ABF1 PF04684.8 KFH40319.1 - 0.86 8.3 6.3 1.4 7.6 4.4 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Aminotran_3 PF00202.16 KFH40320.1 - 1.4e-45 155.6 0.3 1.9e-45 155.2 0.2 1.1 1 0 0 1 1 1 1 Aminotransferase class-III RNB PF00773.14 KFH40321.1 - 7.1e-94 314.7 0.2 1.1e-93 314.1 0.2 1.3 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 KFH40321.1 - 4e-09 36.6 0.7 1.4e-08 34.8 0.1 2.3 2 1 0 2 2 2 1 PIN domain DUF3958 PF13125.1 KFH40321.1 - 0.014 15.2 2.6 0.034 14.0 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3958) OB_RNB PF08206.6 KFH40321.1 - 0.053 13.0 0.0 0.17 11.4 0.0 1.9 1 0 0 1 1 1 0 Ribonuclease B OB domain zf-met PF12874.2 KFH40322.1 - 8.3e-06 25.8 1.0 1.4e-05 25.0 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.4 KFH40322.1 - 3.2e-05 23.5 0.2 4.5e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.6 KFH40322.1 - 0.052 12.8 0.9 0.096 11.9 0.6 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Tim54 PF11711.3 KFH40323.1 - 4.5e-123 410.6 1.1 5.2e-123 410.4 0.8 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 RR_TM4-6 PF06459.7 KFH40323.1 - 0.21 11.4 6.4 0.073 12.9 2.3 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Acyl_transf_3 PF01757.17 KFH40324.1 - 8.4e-43 146.4 33.1 8.4e-43 146.4 23.0 1.4 2 0 0 2 2 2 1 Acyltransferase family Y_phosphatase3 PF13350.1 KFH40325.1 - 1.9e-32 112.7 0.0 2.5e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 KFH40325.1 - 3.2e-10 39.9 0.1 3e-09 36.8 0.0 2.4 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 KFH40325.1 - 0.00027 20.3 0.0 0.00038 19.8 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 KFH40325.1 - 0.054 12.8 0.0 0.079 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KFH40325.1 - 0.07 13.1 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate GST_N_3 PF13417.1 KFH40326.1 - 7.2e-11 42.1 0.3 1.3e-10 41.3 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFH40326.1 - 1.2e-07 31.5 0.4 2.2e-07 30.6 0.3 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFH40326.1 - 0.00025 21.4 0.1 0.00039 20.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFH40326.1 - 0.0012 18.7 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KFH40326.1 - 0.006 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain SMP PF04927.7 KFH40327.1 - 4.8e-15 55.2 14.1 1.5e-10 40.8 3.5 2.1 1 1 1 2 2 2 2 Seed maturation protein Ifi-6-16 PF06140.8 KFH40327.1 - 0.23 11.2 1.6 1.4 8.7 0.1 2.0 2 0 0 2 2 2 0 Interferon-induced 6-16 family Amidohydro_3 PF07969.6 KFH40328.1 - 1.6e-62 212.0 3.8 1.9e-62 211.7 2.6 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KFH40328.1 - 0.0016 18.2 0.0 0.0042 16.8 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase PTS-HPr PF00381.14 KFH40328.1 - 0.088 12.7 0.1 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 PTS HPr component phosphorylation site SelP_N PF04592.9 KFH40331.1 - 2 7.7 5.9 2.2 7.6 4.1 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region MFS_1 PF07690.11 KFH40332.1 - 7.8e-17 61.0 11.0 1.4e-16 60.1 7.4 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily DAGAT PF03982.8 KFH40333.1 - 2.2e-93 312.2 0.0 3.1e-93 311.7 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase SUN PF03856.8 KFH40335.1 - 3e-81 272.3 8.3 3.8e-81 272.0 5.7 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Dus PF01207.12 KFH40335.1 - 0.078 11.7 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Glyco_hydro_114 PF03537.8 KFH40336.1 - 7.6e-13 48.0 0.0 1.4e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 zf-H2C2_2 PF13465.1 KFH40337.1 - 1.5e-16 59.7 18.3 8.2e-08 32.1 1.4 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KFH40337.1 - 8.3e-11 41.5 23.8 0.0031 17.7 5.4 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFH40337.1 - 7.4e-09 35.3 21.3 0.0046 17.2 4.3 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-CHCC PF10276.4 KFH40337.1 - 0.085 12.7 6.7 0.59 10.0 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger domain zf-C2H2_jaz PF12171.3 KFH40337.1 - 0.13 12.4 9.5 0.64 10.2 2.5 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 KFH40337.1 - 0.13 12.2 6.1 4.3 7.3 1.7 2.9 2 1 0 2 2 2 0 Zinc ribbon domain zf-Di19 PF05605.7 KFH40337.1 - 0.14 12.3 12.4 0.58 10.3 4.8 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 KFH40337.1 - 0.24 11.0 5.7 0.12 12.0 0.4 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF904 PF06005.7 KFH40337.1 - 0.27 11.5 0.2 0.27 11.5 0.1 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF904) Rad50_zn_hook PF04423.9 KFH40337.1 - 0.36 10.3 4.0 6.6 6.2 0.3 3.2 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-C2H2_6 PF13912.1 KFH40337.1 - 0.61 10.0 11.4 0.64 10.0 0.0 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Zn_Tnp_IS1595 PF12760.2 KFH40337.1 - 1.1 9.1 7.4 3.8 7.3 2.2 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DZR PF12773.2 KFH40337.1 - 1.6 8.6 5.4 17 5.3 3.8 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_3 PF14369.1 KFH40337.1 - 2.7 8.0 5.1 17 5.5 0.1 2.9 3 0 0 3 3 3 0 zinc-finger zf-BED PF02892.10 KFH40337.1 - 3 7.6 8.2 1.2 8.8 2.6 2.3 2 0 0 2 2 2 0 BED zinc finger NIT PF08376.5 KFH40338.1 - 0.0019 17.7 2.1 0.0023 17.4 1.5 1.2 1 0 0 1 1 1 1 Nitrate and nitrite sensing Atg14 PF10186.4 KFH40338.1 - 0.0043 16.0 0.6 0.0043 16.0 0.4 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 MscS_porin PF12795.2 KFH40338.1 - 0.011 15.0 1.6 0.013 14.8 1.1 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Sec5 PF15469.1 KFH40338.1 - 0.015 14.9 0.4 0.02 14.6 0.3 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec5 DUF3348 PF11828.3 KFH40338.1 - 0.019 14.3 0.9 0.022 14.1 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) GrpE PF01025.14 KFH40338.1 - 0.029 13.9 3.8 0.035 13.6 2.6 1.1 1 0 0 1 1 1 0 GrpE IncA PF04156.9 KFH40338.1 - 0.067 12.7 5.0 0.093 12.3 3.5 1.3 1 0 0 1 1 1 0 IncA protein EAP30 PF04157.11 KFH40338.1 - 0.069 12.2 1.5 0.074 12.1 1.0 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family DUF3782 PF12644.2 KFH40338.1 - 0.1 12.4 1.5 0.19 11.5 1.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) FTA4 PF13093.1 KFH40338.1 - 0.16 11.4 2.1 0.18 11.1 1.4 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 RapA_C PF12137.3 KFH40338.1 - 0.17 10.6 2.8 0.2 10.4 1.9 1.1 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal FUSC PF04632.7 KFH40338.1 - 0.24 9.7 0.9 0.23 9.8 0.6 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Spc7 PF08317.6 KFH40338.1 - 0.31 9.6 3.9 0.34 9.5 2.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6 PF04111.7 KFH40338.1 - 0.53 9.2 2.7 0.57 9.1 1.9 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Snapin_Pallidin PF14712.1 KFH40338.1 - 0.73 10.1 5.2 0.99 9.7 2.9 1.7 1 1 1 2 2 2 0 Snapin/Pallidin Acetyltransf_1 PF00583.19 KFH40339.1 - 2.3e-09 37.1 0.0 3.8e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFH40339.1 - 1.8e-08 34.4 0.0 3.1e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFH40339.1 - 0.002 18.2 0.3 0.0059 16.7 0.1 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFH40339.1 - 0.031 14.1 0.0 0.072 12.9 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFH40339.1 - 0.054 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Thioredoxin PF00085.15 KFH40342.1 - 3.7e-24 84.3 0.0 4.9e-24 83.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KFH40342.1 - 4e-07 30.0 0.0 9.1e-07 28.9 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 KFH40342.1 - 1.4e-05 25.0 0.0 2.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 KFH40342.1 - 2.1e-05 24.1 0.0 2.9e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KFH40342.1 - 4e-05 23.1 0.0 4.8e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.1 KFH40342.1 - 6.5e-05 23.0 0.1 0.00044 20.4 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain HyaE PF07449.6 KFH40342.1 - 0.0012 18.6 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.1 KFH40342.1 - 0.0021 17.6 0.0 0.0029 17.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Condensation PF00668.15 KFH40344.1 - 1.9e-05 23.6 0.1 0.038 12.8 0.0 2.2 2 0 0 2 2 2 2 Condensation domain AATase PF07247.7 KFH40344.1 - 0.00099 17.7 0.0 0.0023 16.5 0.0 1.6 2 0 0 2 2 2 1 Alcohol acetyltransferase NACHT PF05729.7 KFH40344.1 - 0.15 11.6 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain SUV3_C PF12513.3 KFH40345.1 - 1.1e-10 40.7 0.1 2.4e-10 39.6 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 KFH40345.1 - 4e-08 32.9 0.0 9.9e-08 31.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4267 PF14087.1 KFH40347.1 - 0.022 14.3 0.6 0.032 13.7 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4267) DUF3482 PF11981.3 KFH40347.1 - 0.065 12.4 0.4 0.11 11.6 0.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3482) TraD PF06412.6 KFH40347.1 - 0.079 12.5 0.9 0.21 11.2 0.6 1.8 1 1 0 1 1 1 0 Conjugal transfer protein TraD DSPc PF00782.15 KFH40348.1 - 2e-06 27.3 0.0 4.1e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Synaptobrevin PF00957.16 KFH40349.1 - 6.1e-32 109.0 0.3 8.1e-32 108.6 0.2 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KFH40349.1 - 1.8e-23 81.8 0.0 2.7e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain SpoIIAA-like PF11964.3 KFH40349.1 - 0.086 13.1 0.1 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 SpoIIAA-like adh_short PF00106.20 KFH40350.1 - 2.9e-16 59.8 0.3 9e-16 58.2 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KFH40350.1 - 2.6e-08 33.7 0.0 5.4e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFH40350.1 - 0.00012 21.5 0.0 0.0002 20.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KFH40350.1 - 0.00069 19.4 0.0 0.0067 16.2 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KFH40350.1 - 0.039 13.9 0.0 0.13 12.2 0.0 1.9 1 0 0 1 1 1 0 NADH(P)-binding AA_permease PF00324.16 KFH40352.1 - 3e-121 405.0 37.9 3.8e-121 404.7 26.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFH40352.1 - 2.4e-38 131.7 40.6 3e-38 131.4 28.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFH40355.1 - 8.9e-62 208.9 46.6 1.1e-61 208.6 32.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFH40355.1 - 1.7e-32 112.4 44.8 2.3e-32 112.0 31.0 1.0 1 0 0 1 1 1 1 Amino acid permease Zn_clus PF00172.13 KFH40356.1 - 8.4e-07 28.8 6.7 1.5e-06 27.9 4.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KFH40357.1 - 5.1e-27 94.5 36.7 5.1e-27 94.5 25.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Fis1_TPR_C PF14853.1 KFH40358.1 - 1.3e-24 85.7 2.8 2e-24 85.2 2.0 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 KFH40358.1 - 1.3e-17 62.7 0.0 2.6e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_16 PF13432.1 KFH40358.1 - 0.0037 17.9 0.9 0.0066 17.0 0.6 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFH40358.1 - 0.037 13.9 2.2 0.079 12.9 1.5 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Septin PF00735.13 KFH40359.1 - 7.2e-121 402.5 0.1 7.2e-121 402.5 0.1 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KFH40359.1 - 3.2e-07 30.3 0.0 7.6e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 KFH40359.1 - 5.8e-05 23.4 0.8 0.017 15.4 0.0 2.5 2 0 0 2 2 2 1 ABC transporter GTP_EFTU PF00009.22 KFH40359.1 - 6.3e-05 22.4 1.6 0.00062 19.2 0.0 2.8 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KFH40359.1 - 7e-05 22.0 0.5 0.00055 19.1 0.3 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 KFH40359.1 - 0.00031 20.2 1.0 0.0016 17.9 0.2 2.2 2 1 0 2 2 2 1 AAA-like domain AIG1 PF04548.11 KFH40359.1 - 0.00086 18.4 1.5 0.0019 17.3 0.0 2.1 2 0 0 2 2 2 1 AIG1 family AAA_16 PF13191.1 KFH40359.1 - 0.0028 17.6 0.0 0.013 15.5 0.0 2.0 3 0 0 3 3 2 1 AAA ATPase domain Miro PF08477.8 KFH40359.1 - 0.0028 18.1 0.3 0.01 16.3 0.0 2.1 2 0 0 2 2 1 1 Miro-like protein Ras PF00071.17 KFH40359.1 - 0.0034 16.7 0.3 0.031 13.6 0.0 2.5 3 0 0 3 3 3 1 Ras family Dynamin_N PF00350.18 KFH40359.1 - 0.004 16.9 4.0 0.52 10.1 0.0 3.3 3 0 0 3 3 3 1 Dynamin family FtsK_SpoIIIE PF01580.13 KFH40359.1 - 0.0048 16.4 0.0 0.021 14.3 0.0 2.0 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.1 KFH40359.1 - 0.0068 16.5 0.0 0.026 14.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KFH40359.1 - 0.0072 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain MobB PF03205.9 KFH40359.1 - 0.069 12.8 1.8 0.22 11.2 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KFH40359.1 - 0.081 13.0 0.5 0.48 10.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.1 KFH40359.1 - 0.089 12.3 0.8 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KFH40359.1 - 0.094 12.1 0.0 0.27 10.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain Strep_SA_rep PF06696.6 KFH40359.1 - 0.16 11.7 2.8 0.2 11.4 0.9 1.9 1 1 1 2 2 2 0 Streptococcal surface antigen repeat ATP_bind_1 PF03029.12 KFH40359.1 - 0.23 10.9 2.2 9.5 5.6 0.0 3.0 3 2 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_32 PF13654.1 KFH40359.1 - 0.29 9.7 11.1 0.43 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Exonuc_VII_L PF02601.10 KFH40359.1 - 3.6 6.6 11.5 5.1 6.1 7.5 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.14 KFH40359.1 - 3.8 5.2 8.4 6 4.5 5.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 KFH40359.1 - 5.4 6.5 9.0 8.3 5.9 6.3 1.3 1 0 0 1 1 1 0 IncA protein DUF87 PF01935.12 KFH40359.1 - 5.9 6.6 8.1 2.9 7.6 0.0 2.6 3 0 0 3 3 2 0 Domain of unknown function DUF87 Ku PF02735.11 KFH40360.1 - 2.7e-41 141.1 0.0 3.7e-40 137.4 0.0 2.2 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 KFH40360.1 - 2.8e-35 121.7 0.0 4e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 KFH40360.1 - 8.5e-15 55.0 0.2 2.8e-14 53.4 0.2 1.9 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 KFH40360.1 - 2.1e-11 43.0 0.0 4.4e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 SAP domain Toprim_3 PF13362.1 KFH40360.1 - 0.0022 18.1 0.0 0.51 10.6 0.0 2.8 2 0 0 2 2 2 1 Toprim domain HeH PF12949.2 KFH40360.1 - 0.011 15.2 0.1 0.033 13.7 0.0 1.8 1 0 0 1 1 1 0 HeH/LEM domain Complex1_51K PF01512.12 KFH40360.1 - 0.06 13.0 0.0 0.39 10.4 0.0 2.1 2 0 0 2 2 2 0 Respiratory-chain NADH dehydrogenase 51 Kd subunit Ferrochelatase PF00762.14 KFH40361.1 - 1.2e-92 310.2 0.0 1.4e-92 310.0 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase MP PF01107.13 KFH40361.1 - 0.16 11.2 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Viral movement protein (MP) DUF793 PF05633.6 KFH40361.1 - 0.18 10.5 0.1 0.3 9.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF793) p450 PF00067.17 KFH40362.1 - 9.1e-68 228.8 0.0 1.1e-67 228.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4296 PF14129.1 KFH40362.1 - 0.059 13.5 0.1 2.3 8.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4296) adh_short PF00106.20 KFH40363.1 - 1.5e-20 73.7 0.2 2.4e-20 73.1 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH40363.1 - 1.1e-10 41.5 0.1 1.7e-10 40.8 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFH40363.1 - 5.5e-07 29.6 0.0 7.4e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KFH40363.1 - 0.00025 20.5 0.0 0.0003 20.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFH40363.1 - 0.0012 18.9 0.6 0.0026 17.7 0.4 1.8 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KFH40363.1 - 0.0033 16.3 0.0 0.0045 15.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 KFH40363.1 - 0.0062 16.6 0.0 0.015 15.3 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NolV PF06635.7 KFH40364.1 - 0.033 13.3 0.1 0.072 12.2 0.0 1.5 2 0 0 2 2 2 0 Nodulation protein NolV FAD_binding_3 PF01494.14 KFH40365.1 - 7.9e-67 225.8 0.2 9.8e-67 225.4 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFH40365.1 - 3.2e-07 29.5 0.1 7.9e-07 28.2 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase TrkA_N PF02254.13 KFH40365.1 - 5e-05 23.2 0.0 0.00012 22.0 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox_3 PF13738.1 KFH40365.1 - 6.9e-05 23.0 0.0 0.00014 21.9 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFH40365.1 - 0.0003 19.7 0.5 0.00076 18.4 0.3 1.6 1 1 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 KFH40365.1 - 0.0003 19.9 0.1 0.00075 18.6 0.1 1.6 1 0 0 1 1 1 1 Thi4 family Phe_hydrox_dim PF07976.7 KFH40365.1 - 0.00037 20.1 0.0 0.0009 18.8 0.0 1.6 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.9 KFH40365.1 - 0.00039 20.3 0.1 0.00086 19.2 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KFH40365.1 - 0.0007 19.2 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 KFH40365.1 - 0.00077 18.0 0.4 0.013 13.9 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein UDPG_MGDP_dh_N PF03721.9 KFH40365.1 - 0.0023 17.3 0.0 0.0036 16.6 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_8 PF13450.1 KFH40365.1 - 0.0046 16.9 0.1 0.013 15.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KFH40365.1 - 0.007 15.0 0.0 0.01 14.5 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase FAD_oxidored PF12831.2 KFH40365.1 - 0.0076 15.3 0.9 0.016 14.3 0.5 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.11 KFH40365.1 - 0.01 15.2 0.0 0.022 14.1 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 KFH40365.1 - 0.018 15.1 0.0 0.039 14.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 KFH40365.1 - 0.02 13.8 0.3 0.037 12.9 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein DUF3344 PF11824.3 KFH40365.1 - 0.026 13.9 0.1 0.046 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3344) F420_oxidored PF03807.12 KFH40365.1 - 0.054 13.9 0.1 0.17 12.2 0.0 1.9 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent ADH_zinc_N PF00107.21 KFH40366.1 - 3.5e-20 71.8 0.0 5.4e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFH40366.1 - 1.1e-05 26.3 0.0 2.2e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Chorismate_bind PF00425.13 KFH40367.1 - 2.4e-67 226.9 0.0 2.6e-63 213.7 0.0 2.2 2 0 0 2 2 2 2 chorismate binding enzyme GATase PF00117.23 KFH40367.1 - 1e-25 90.3 0.0 2.2e-25 89.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 KFH40367.1 - 1.5e-15 57.4 0.0 4.8e-15 55.8 0.0 1.9 1 1 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 KFH40367.1 - 0.00019 20.9 0.6 0.0017 17.8 0.4 2.1 1 1 0 1 1 1 1 Peptidase C26 ADH_zinc_N PF00107.21 KFH40368.1 - 4.3e-26 90.9 0.5 8.2e-26 90.0 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFH40368.1 - 2.3e-13 49.8 0.0 7.4e-13 48.2 0.0 1.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KFH40368.1 - 4.5e-12 46.9 0.0 1e-11 45.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 KFH40368.1 - 0.0014 18.5 0.0 0.0029 17.6 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.16 KFH40368.1 - 0.0066 16.0 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Amidase PF01425.16 KFH40369.1 - 1.4e-76 258.1 0.0 1.8e-76 257.8 0.0 1.1 1 0 0 1 1 1 1 Amidase BLVR PF06375.6 KFH40370.1 - 0.055 13.2 0.6 0.072 12.9 0.4 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Methyltransf_11 PF08241.7 KFH40372.1 - 8.1e-11 42.2 0.0 2.1e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH40372.1 - 2.4e-09 37.1 0.0 5e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH40372.1 - 9.2e-09 35.8 0.0 1.7e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFH40372.1 - 1.1e-08 35.3 0.0 2.3e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH40372.1 - 8.3e-07 28.7 0.0 1.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFH40372.1 - 4.7e-06 26.6 0.1 2.3e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH40372.1 - 5.7e-06 26.7 0.0 1.2e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFH40372.1 - 7.7e-05 21.9 0.0 0.00013 21.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 KFH40372.1 - 0.00018 21.2 0.0 0.00041 20.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFH40372.1 - 0.0031 16.8 0.0 0.011 15.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.14 KFH40372.1 - 0.016 14.7 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.10 KFH40372.1 - 0.027 14.0 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase CMAS PF02353.15 KFH40372.1 - 0.046 12.7 0.0 0.091 11.8 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Complex1_LYR_2 PF13233.1 KFH40374.1 - 0.019 15.4 0.2 0.073 13.5 0.0 1.8 2 0 0 2 2 2 0 Complex1_LYR-like DUF4042 PF13251.1 KFH40374.1 - 0.087 12.2 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4042) Complex1_LYR PF05347.10 KFH40374.1 - 0.11 12.2 0.2 0.23 11.2 0.1 1.6 1 1 0 1 1 1 0 Complex 1 protein (LYR family) Exo_endo_phos PF03372.18 KFH40375.1 - 2.3e-23 83.4 0.1 3.8e-23 82.7 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 KFH40375.1 - 8.7e-14 50.7 7.7 1e-07 31.4 0.3 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFH40375.1 - 2.9e-05 23.5 3.1 0.1 12.7 0.0 4.4 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_8 PF13855.1 KFH40375.1 - 6.6e-05 22.5 7.1 0.00091 18.9 0.2 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_7 PF13504.1 KFH40375.1 - 0.0018 18.1 3.7 18 6.0 0.1 4.1 4 0 0 4 4 4 1 Leucine rich repeat Herpes_LMP2 PF07415.6 KFH40375.1 - 0.28 9.7 3.0 0.43 9.1 2.1 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein AAA_16 PF13191.1 KFH40376.1 - 1.2e-07 31.9 0.0 5.5e-07 29.7 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 KFH40376.1 - 6.7e-07 29.1 0.0 1.7e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 KFH40376.1 - 6.2e-05 21.9 0.2 0.00017 20.5 0.1 1.7 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 KFH40376.1 - 8.4e-05 22.7 0.0 0.00048 20.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KFH40376.1 - 0.0016 18.1 0.1 0.0044 16.7 0.0 1.7 2 0 0 2 2 2 1 Archaeal ATPase RNA_helicase PF00910.17 KFH40376.1 - 0.0088 16.2 0.0 0.022 14.9 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA PF00004.24 KFH40376.1 - 0.009 16.2 1.2 0.068 13.3 0.1 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KFH40376.1 - 0.028 14.3 0.0 0.13 12.1 0.0 2.2 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 KFH40376.1 - 0.088 11.4 0.0 0.2 10.3 0.0 1.5 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Glyco_hydro_3 PF00933.16 KFH40377.1 - 1.4e-77 260.6 0.0 2.1e-77 260.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KFH40377.1 - 8.2e-69 231.5 0.0 2.3e-68 230.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KFH40377.1 - 1.6e-25 88.8 0.2 3.6e-25 87.7 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 KFH40377.1 - 1.8e-18 66.6 0.2 3e-18 65.8 0.1 1.4 1 0 0 1 1 1 1 PA14 domain bZIP_1 PF00170.16 KFH40378.1 - 0.0096 15.8 18.0 0.25 11.3 12.5 2.3 1 1 0 1 1 1 1 bZIP transcription factor Mnd1 PF03962.10 KFH40378.1 - 0.017 14.8 4.1 0.027 14.1 2.8 1.3 1 0 0 1 1 1 0 Mnd1 family Guanylate_kin PF00625.16 KFH40378.1 - 0.068 12.6 0.5 0.1 12.0 0.4 1.2 1 0 0 1 1 1 0 Guanylate kinase DUF3355 PF11835.3 KFH40378.1 - 0.96 9.2 6.3 0.83 9.4 2.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3355) CAF-1_p150 PF11600.3 KFH40378.1 - 3.1 7.1 10.8 6.5 6.0 7.5 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal eRF1_2 PF03464.10 KFH40381.1 - 1.4e-47 161.3 0.1 2.6e-47 160.4 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 KFH40381.1 - 2.2e-40 137.4 0.4 4.9e-40 136.3 0.3 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 KFH40381.1 - 7e-28 96.8 0.0 1.4e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 Flavodoxin_NdrI PF07972.6 KFH40381.1 - 0.025 14.4 0.1 0.17 11.8 0.1 2.3 1 1 0 1 1 1 0 NrdI Flavodoxin like PfkB PF00294.19 KFH40382.1 - 5.1e-24 84.9 0.0 6.1e-24 84.6 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase WHIM1 PF15612.1 KFH40383.1 - 0.0021 17.8 0.0 0.0045 16.8 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM2 PF15613.1 KFH40383.1 - 0.027 14.4 0.1 0.063 13.2 0.1 1.6 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 2 Plasmid_stabil PF05016.9 KFH40383.1 - 0.04 14.2 0.5 0.089 13.1 0.4 1.5 1 0 0 1 1 1 0 Plasmid stabilisation system protein EST1_DNA_bind PF10373.4 KFH40384.1 - 5.6e-48 163.5 0.0 9.3e-48 162.8 0.0 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 KFH40384.1 - 4.2e-20 72.0 0.0 2.1e-19 69.8 0.0 2.2 2 0 0 2 2 2 1 Telomerase activating protein Est1 DUF1770 PF08589.5 KFH40385.1 - 3.2e-26 91.8 1.9 4e-26 91.5 1.3 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) PH PF00169.24 KFH40386.1 - 3.1e-05 24.1 0.0 9.9e-05 22.4 0.0 1.9 1 1 0 1 1 1 1 PH domain GRAM PF02893.15 KFH40386.1 - 0.061 12.8 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 GRAM domain Mnd1 PF03962.10 KFH40386.1 - 0.56 9.8 3.3 2.9 7.5 1.4 2.3 2 0 0 2 2 2 0 Mnd1 family PfkB PF00294.19 KFH40387.1 - 5.4e-37 127.5 0.0 6.5e-37 127.2 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HyaE PF07449.6 KFH40387.1 - 0.061 13.2 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Ribosomal_L2_C PF03947.13 KFH40388.1 - 2e-38 131.1 3.2 2.7e-38 130.6 2.2 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KFH40388.1 - 0.0079 16.1 0.1 0.039 13.9 0.1 2.1 1 1 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain TMEM171 PF15471.1 KFH40389.1 - 2 7.1 3.4 3.9 6.1 2.4 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 F-box PF00646.28 KFH40390.1 - 0.038 13.6 0.2 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 F-box domain Bac_rhamnosid PF05592.6 KFH40391.1 - 1.1e-177 591.3 0.2 1.3e-177 591.0 0.1 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 KFH40391.1 - 3.2e-57 192.8 0.1 6.4e-57 191.8 0.1 1.5 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Sulfate_transp PF00916.15 KFH40392.1 - 8.8e-52 175.8 4.7 1.5e-51 175.1 3.3 1.3 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KFH40392.1 - 2.9e-28 97.3 4.2 2.9e-28 97.3 2.9 2.3 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KFH40392.1 - 5.5e-16 58.0 0.0 1.3e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 KFH40392.1 - 0.00013 21.9 0.0 0.00036 20.4 0.0 1.8 1 1 0 1 1 1 1 STAS domain Thiolase_N PF00108.18 KFH40393.1 - 1.1e-68 231.1 0.0 1.5e-68 230.6 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KFH40393.1 - 1.1e-41 141.1 0.2 2.5e-41 139.9 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KFH40393.1 - 0.079 12.6 0.1 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III MU117 PF15474.1 KFH40394.1 - 1.4e-12 47.8 4.5 3.3e-12 46.7 3.1 1.7 1 0 0 1 1 1 1 Meiotically up-regulated gene family PSDC PF12588.3 KFH40395.1 - 2.3e-32 111.5 0.0 3.3e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 KFH40395.1 - 5.7e-25 87.8 0.0 7.2e-24 84.2 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylserine decarboxylase MUG113 PF13455.1 KFH40397.1 - 3.1e-11 43.5 2.0 3.1e-11 43.5 1.4 2.4 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 KFH40397.1 - 1.2e-07 32.0 11.2 5.2e-07 29.9 3.4 3.3 2 1 0 2 2 2 1 T5orf172 domain OmpH PF03938.9 KFH40397.1 - 0.017 15.0 0.7 0.032 14.1 0.5 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Pectate_lyase PF03211.8 KFH40399.1 - 1.2e-82 276.4 4.2 1.5e-82 276.1 2.9 1.0 1 0 0 1 1 1 1 Pectate lyase UQ_con PF00179.21 KFH40401.1 - 3.1e-41 140.0 0.0 3.7e-41 139.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFH40401.1 - 5e-08 32.7 0.0 6e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFH40401.1 - 0.05 13.5 0.2 0.079 12.8 0.1 1.5 1 1 0 1 1 1 0 RWD domain PSII_Pbs27 PF13326.1 KFH40401.1 - 0.053 13.5 0.0 9.6 6.1 0.0 2.3 2 1 0 2 2 2 0 Photosystem II Pbs27 UEV PF05743.8 KFH40401.1 - 0.056 13.1 0.1 0.07 12.8 0.1 1.3 1 0 0 1 1 1 0 UEV domain DUF706 PF05153.10 KFH40402.1 - 7.9e-123 408.6 0.0 1.3e-122 408.0 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF706) Nop52 PF05997.7 KFH40403.1 - 2.7e-41 141.3 0.0 3.6e-41 140.9 0.0 1.2 1 0 0 1 1 1 1 Nucleolar protein,Nop52 RabGAP-TBC PF00566.13 KFH40404.1 - 7.6e-38 130.1 0.1 6.4e-22 78.0 0.0 3.0 2 1 0 2 2 2 2 Rab-GTPase-TBC domain W2 PF02020.13 KFH40406.1 - 0.037 13.9 1.2 0.24 11.3 0.3 2.6 2 0 0 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon CorA PF01544.13 KFH40407.1 - 3.3e-09 36.2 0.1 6.6e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein BAF1_ABF1 PF04684.8 KFH40407.1 - 0.0027 16.6 2.1 0.0027 16.6 1.5 2.3 2 0 0 2 2 2 1 BAF1 / ABF1 chromatin reorganising factor NOA36 PF06524.7 KFH40407.1 - 0.012 14.8 4.8 0.029 13.6 3.3 1.5 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.4 KFH40407.1 - 5.6 5.5 21.1 15 4.1 14.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 KFH40407.1 - 7.2 4.5 10.0 1.8 6.4 3.4 2.2 2 0 0 2 2 2 0 CDC45-like protein Vezatin PF12632.2 KFH40408.1 - 9e-50 169.0 0.0 1.4e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes DUF4231 PF14015.1 KFH40408.1 - 0.078 12.9 1.6 0.5 10.3 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) SLX9 PF15341.1 KFH40409.1 - 8.4 6.8 8.3 2.7 8.4 1.6 2.5 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 GATA PF00320.22 KFH40410.1 - 4.2e-14 51.6 1.0 8.8e-14 50.5 0.7 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF745 PF05335.8 KFH40410.1 - 0.00044 19.8 4.0 0.00081 18.9 2.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF745) CENP-F_leu_zip PF10473.4 KFH40410.1 - 0.0014 18.4 16.8 0.051 13.4 1.2 2.4 1 1 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2353 PF09789.4 KFH40410.1 - 0.033 13.4 9.3 0.061 12.5 6.4 1.4 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Striatin PF08232.7 KFH40410.1 - 0.046 14.0 12.9 0.064 13.5 4.5 2.4 1 1 1 2 2 2 0 Striatin family Filament PF00038.16 KFH40410.1 - 0.21 11.0 12.9 0.54 9.6 7.8 1.9 1 1 1 2 2 2 0 Intermediate filament protein DUF4613 PF15390.1 KFH40410.1 - 1.1 7.3 3.6 1.4 6.9 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Herpes_UL25 PF01499.11 KFH40410.1 - 5.1 5.2 8.5 8 4.6 5.9 1.4 1 0 0 1 1 1 0 Herpesvirus UL25 family Acetyltransf_1 PF00583.19 KFH40411.1 - 0.025 14.6 0.2 0.043 13.8 0.2 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFH40411.1 - 0.066 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFH40411.1 - 0.077 13.1 0.2 0.3 11.2 0.1 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Pho86 PF11124.3 KFH40411.1 - 0.13 11.2 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 DUF2296 PF10058.4 KFH40412.1 - 0.053 13.2 0.2 0.053 13.2 0.1 2.3 1 1 1 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) zf-AN1 PF01428.11 KFH40412.1 - 0.07 13.0 1.7 0.07 13.0 1.2 1.7 1 1 0 1 1 1 0 AN1-like Zinc finger zf-B_box PF00643.19 KFH40412.1 - 0.15 11.9 10.5 0.48 10.3 7.3 1.8 1 1 0 1 1 1 0 B-box zinc finger PHD_2 PF13831.1 KFH40412.1 - 0.61 9.4 8.4 2.8 7.3 0.1 2.5 2 1 0 2 2 2 0 PHD-finger Tnp_zf-ribbon_2 PF13842.1 KFH40412.1 - 0.88 10.0 7.8 1.7 9.1 5.4 1.5 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon Mit_KHE1 PF10173.4 KFH40413.1 - 1.5e-57 194.4 1.1 2.2e-57 193.9 0.7 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Apc4_WD40 PF12894.2 KFH40413.1 - 0.012 15.1 0.3 1.7 8.2 0.0 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Svf1 PF08622.5 KFH40414.1 - 8.4e-128 425.9 0.0 9.6e-128 425.7 0.0 1.0 1 0 0 1 1 1 1 Svf1-like YjbE PF11106.3 KFH40415.1 - 0.048 13.6 1.8 0.067 13.1 1.2 1.2 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE Histone PF00125.19 KFH40416.1 - 9.1e-06 25.7 1.1 1.2e-05 25.3 0.8 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 MOSC_N PF03476.11 KFH40417.1 - 3.3e-13 49.4 0.0 8.3e-13 48.0 0.0 1.7 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 KFH40417.1 - 3.1e-12 46.1 0.0 5.1e-09 35.7 0.0 2.4 1 1 0 2 2 2 2 MOSC domain NRDE-2 PF08424.5 KFH40417.1 - 0.097 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference EthD PF07110.6 KFH40420.1 - 3.1e-06 28.0 0.0 0.0033 18.3 0.0 2.2 2 0 0 2 2 2 2 EthD domain DUF4286 PF14114.1 KFH40420.1 - 0.0088 16.2 0.0 0.3 11.3 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4286) Acetyltransf_8 PF13523.1 KFH40420.1 - 0.047 13.5 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Abhydrolase_2 PF02230.11 KFH40422.1 - 8.5e-32 110.3 0.0 8.2e-21 74.4 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KFH40422.1 - 8.8e-13 48.6 1.5 1.4e-12 47.9 1.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH40422.1 - 1.5e-08 34.4 0.0 3.3e-08 33.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 KFH40422.1 - 3.2e-08 33.2 0.0 5.9e-08 32.4 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 KFH40422.1 - 1e-07 31.4 1.2 4.6e-05 22.7 0.0 2.5 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 KFH40422.1 - 0.0016 18.0 0.0 0.0081 15.7 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 KFH40422.1 - 0.024 13.9 0.0 0.21 10.8 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family Esterase_phd PF10503.4 KFH40422.1 - 0.036 13.3 0.1 0.054 12.7 0.0 1.4 1 1 0 1 1 1 0 Esterase PHB depolymerase Mannosyl_trans2 PF04188.8 KFH40423.1 - 7.6e-61 206.3 10.5 1.2e-60 205.7 7.3 1.2 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V)) PRP1_N PF06424.7 KFH40426.1 - 0.065 13.5 3.0 0.077 13.3 2.1 1.0 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal XAP5 PF04921.9 KFH40426.1 - 0.22 11.0 4.1 0.25 10.8 2.8 1.0 1 0 0 1 1 1 0 XAP5, circadian clock regulator IATP PF04568.7 KFH40426.1 - 1.3 9.0 6.9 1.9 8.5 4.8 1.2 1 1 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP Ribosomal_60s PF00428.14 KFH40426.1 - 1.6 9.2 6.1 1.8 9.0 4.3 1.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein Patched PF02460.13 KFH40427.1 - 3.7e-73 246.7 14.6 2.3e-48 164.7 0.0 2.1 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 KFH40427.1 - 9.4e-51 171.2 4.4 9.4e-51 171.2 3.0 2.5 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 KFH40427.1 - 4.1e-05 22.4 9.5 4.1e-05 22.4 6.6 3.2 2 2 0 2 2 2 1 MMPL family Folate_rec PF03024.9 KFH40427.1 - 0.0022 17.6 0.7 0.0046 16.6 0.5 1.4 1 0 0 1 1 1 1 Folate receptor family Glyco_hydro_47 PF01532.15 KFH40428.1 - 8.5e-136 453.1 0.9 9.7e-136 453.0 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TipAS PF07739.8 KFH40428.1 - 0.00036 20.8 2.4 0.022 15.0 0.0 2.9 3 0 0 3 3 3 2 TipAS antibiotic-recognition domain Rad10 PF03834.9 KFH40429.1 - 1.7e-30 104.4 0.0 2.6e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 KFH40429.1 - 0.0086 16.2 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain Lactamase_B_2 PF12706.2 KFH40430.1 - 4.5e-38 130.7 0.0 5.5e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KFH40430.1 - 6.7e-11 42.1 0.0 1.1e-10 41.4 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KFH40430.1 - 2.9e-07 30.3 0.1 1.4e-06 28.0 0.0 2.1 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Spuma_A9PTase PF03539.9 KFH40430.1 - 0.12 12.3 0.1 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) MR_MLE_C PF13378.1 KFH40431.1 - 9.6e-19 67.4 0.0 2.8e-18 65.9 0.0 1.8 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KFH40431.1 - 8.1e-14 51.9 0.3 3e-12 46.8 0.0 2.6 3 0 0 3 3 3 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 KFH40431.1 - 0.0013 18.7 0.0 0.0033 17.3 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.6 KFH40431.1 - 0.0064 15.4 0.0 0.0098 14.8 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Gly_kinase PF02595.10 KFH40434.1 - 1.7e-101 339.6 6.6 2e-101 339.4 4.6 1.1 1 0 0 1 1 1 1 Glycerate kinase family APH PF01636.18 KFH40436.1 - 1.7e-15 57.4 0.1 2.6e-15 56.7 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFH40436.1 - 0.00041 19.9 0.0 0.00065 19.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 KFH40436.1 - 0.023 13.6 0.0 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase RNA_polI_A14 PF08203.6 KFH40436.1 - 0.041 14.1 0.0 0.071 13.3 0.0 1.3 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 Arylsulfotran_2 PF14269.1 KFH40437.1 - 5.4e-46 157.0 2.0 7.7e-46 156.5 1.4 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KFH40437.1 - 1.4e-18 66.6 2.7 2.6e-18 65.8 1.9 1.4 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) DUF2457 PF10446.4 KFH40437.1 - 8.5 4.9 23.4 18 3.9 16.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cyclin_N PF00134.18 KFH40439.1 - 2.1e-10 40.2 0.0 3.9e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain COesterase PF00135.23 KFH40440.1 - 1.1e-89 301.6 0.0 1.4e-89 301.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFH40440.1 - 0.0044 16.6 0.1 0.0084 15.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFH40440.1 - 0.013 14.7 0.2 0.026 13.7 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family MFS_1 PF07690.11 KFH40441.1 - 1.1e-20 73.6 26.7 8e-17 60.9 5.6 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH40441.1 - 4.3e-09 35.4 2.6 4.3e-09 35.4 1.8 2.9 2 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.15 KFH40441.1 - 0.002 16.2 0.0 0.13 10.2 0.0 2.3 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family PhoPQ_related PF10142.4 KFH40442.1 - 0.0053 15.2 0.0 0.0094 14.4 0.0 1.3 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein DUF463 PF04317.7 KFH40442.1 - 0.19 10.2 0.0 0.25 9.8 0.0 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 adh_short PF00106.20 KFH40443.1 - 3.3e-22 79.1 0.8 6e-22 78.3 0.6 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH40443.1 - 3.5e-12 46.3 0.1 4.4e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFH40443.1 - 7.6e-11 42.2 0.0 1.1e-10 41.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Chal_sti_synt_C PF02797.10 KFH40443.1 - 0.066 13.1 0.0 7.9 6.3 0.0 2.2 1 1 1 2 2 2 0 Chalcone and stilbene synthases, C-terminal domain LDB19 PF13002.2 KFH40444.1 - 1.4e-32 112.7 0.1 3.4e-32 111.4 0.0 1.5 2 0 0 2 2 2 1 Arrestin_N terminal like Arrestin_N PF00339.24 KFH40444.1 - 2.2e-05 24.3 0.0 7.3e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain AA_permease_2 PF13520.1 KFH40445.1 - 8.3e-52 176.1 33.6 1e-51 175.8 23.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFH40445.1 - 1.3e-19 69.9 23.5 1.3e-19 69.9 16.3 2.2 2 0 0 2 2 2 2 Amino acid permease Polysacc_deac_1 PF01522.16 KFH40447.1 - 1.5e-26 92.4 0.0 2.1e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 KFH40447.1 - 0.0072 15.2 0.0 0.0094 14.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Lipase_GDSL_2 PF13472.1 KFH40447.1 - 0.028 14.5 0.0 1.8 8.7 0.0 2.5 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Med3 PF11593.3 KFH40447.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Glyco_hydro_11 PF00457.12 KFH40449.1 - 3.2e-59 199.3 19.0 7.7e-47 159.0 2.7 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 11 FAR1 PF03101.10 KFH40450.1 - 1.8e-10 41.2 1.1 3.1e-10 40.4 0.8 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain VSP PF03302.8 KFH40452.1 - 0.0039 15.8 0.1 0.0055 15.3 0.1 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein PH PF00169.24 KFH40453.1 - 6.2e-05 23.1 0.0 0.00022 21.3 0.0 1.9 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 KFH40453.1 - 0.00039 20.5 0.0 0.00082 19.5 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Peptidase_S9_N PF02897.10 KFH40453.1 - 0.026 13.1 0.1 0.038 12.5 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Pkinase PF00069.20 KFH40454.1 - 8.4e-63 211.9 0.0 1.4e-62 211.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH40454.1 - 3.4e-25 88.5 0.0 5.6e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KFH40454.1 - 5.4e-10 39.2 0.0 2.3e-09 37.2 0.0 2.2 2 0 0 2 2 2 1 FHA domain Spo0A_C PF08769.6 KFH40454.1 - 0.15 11.9 0.9 0.32 10.8 0.6 1.5 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal DUF726 PF05277.7 KFH40455.1 - 6.1e-126 419.9 1.8 8.6e-126 419.4 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_5 PF12695.2 KFH40455.1 - 0.026 14.2 0.2 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFH40455.1 - 0.026 14.0 0.2 0.54 9.7 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold SpoIIE PF07228.7 KFH40456.1 - 1.7e-05 24.6 0.0 7.7e-05 22.4 0.0 1.9 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KFH40456.1 - 2.6e-05 23.7 0.0 4.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 KFH40456.1 - 0.11 11.8 0.0 0.37 10.1 0.0 1.7 2 0 0 2 2 2 0 Protein phosphatase 2C Fcf1 PF04900.7 KFH40457.1 - 6.3e-25 87.2 0.0 1.3e-24 86.1 0.0 1.6 1 0 0 1 1 1 1 Fcf1 DUF3439 PF11921.3 KFH40457.1 - 0.36 10.5 9.5 0.63 9.7 6.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Zn_clus PF00172.13 KFH40458.1 - 9.9e-09 34.9 12.8 1.5e-08 34.4 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UTP15_C PF09384.5 KFH40459.1 - 1.5e-44 151.2 0.4 3.7e-44 150.0 0.1 1.7 2 0 0 2 2 2 1 UTP15 C terminal WD40 PF00400.27 KFH40459.1 - 2.3e-28 96.9 3.0 5.7e-11 41.8 0.0 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 KFH40459.1 - 4.8e-05 23.0 0.0 1.4 8.7 0.0 4.2 2 1 3 5 5 5 1 Ciliary BBSome complex subunit 2, middle region CPSF_A PF03178.10 KFH40459.1 - 0.0041 16.2 0.0 0.0097 15.0 0.0 1.6 2 0 0 2 2 2 1 CPSF A subunit region Nup160 PF11715.3 KFH40459.1 - 0.006 14.7 1.6 0.15 10.1 0.3 2.4 2 1 1 3 3 3 2 Nucleoporin Nup120/160 adh_short PF00106.20 KFH40462.1 - 0.002 18.0 0.1 1.4 8.7 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KFH40462.1 - 0.0041 16.9 0.0 0.19 11.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase DEAD PF00270.24 KFH40463.1 - 2.3e-17 63.0 0.0 5.5e-17 61.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KFH40463.1 - 1.7e-09 37.7 0.0 5.5e-09 36.1 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KFH40463.1 - 7.4e-09 35.3 0.2 2.1e-08 33.8 0.2 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.11 KFH40463.1 - 0.011 14.9 0.0 0.073 12.2 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein Glyco_hydro_47 PF01532.15 KFH40464.1 - 9.7e-135 449.7 0.0 1.1e-134 449.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pyr_redox_2 PF07992.9 KFH40466.1 - 1.7e-15 57.4 0.0 4.5e-15 56.0 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFH40466.1 - 2e-06 28.0 0.1 0.0021 18.1 0.1 3.1 1 1 2 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFH40466.1 - 1.2e-05 24.3 0.0 0.003 16.5 0.0 2.3 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 KFH40466.1 - 1.4e-05 25.3 0.4 0.00031 21.1 0.7 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFH40466.1 - 0.0015 17.4 0.1 0.26 10.1 0.1 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.1 KFH40466.1 - 0.0023 17.7 0.3 0.11 12.2 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding TrkA_N PF02254.13 KFH40466.1 - 0.1 12.6 0.0 1.7 8.7 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain NUDIX PF00293.23 KFH40467.1 - 2.1e-27 95.3 0.0 3.3e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain RPA_C PF08784.6 KFH40468.1 - 3.6e-21 75.4 0.2 8.2e-21 74.3 0.0 1.7 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 KFH40468.1 - 7.6e-06 25.6 0.0 1.6e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain ACBP PF00887.14 KFH40469.1 - 2.6e-14 52.6 3.8 5.2e-13 48.4 2.6 2.0 1 1 0 1 1 1 1 Acyl CoA binding protein End3 PF12761.2 KFH40470.1 - 2.5e-73 245.9 1.9 4.3e-73 245.1 1.3 1.4 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 KFH40470.1 - 2.8e-48 161.9 0.0 5.5e-47 157.8 0.0 2.4 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 KFH40470.1 - 9.3e-07 27.7 0.6 2.1e-06 26.6 0.1 1.9 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KFH40470.1 - 4.7e-06 26.1 0.1 1.1e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 KFH40470.1 - 7.4e-05 22.8 0.0 0.00027 20.9 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KFH40470.1 - 0.0013 18.4 0.3 0.0049 16.6 0.2 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 KFH40470.1 - 0.005 16.1 0.1 0.014 14.7 0.1 1.8 1 0 0 1 1 1 1 EF hand PilJ PF13675.1 KFH40470.1 - 0.097 13.0 3.3 0.46 10.8 0.3 2.5 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term EMP24_GP25L PF01105.19 KFH40470.1 - 0.16 11.6 2.2 2.8 7.6 0.1 2.6 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD COG2 PF06148.6 KFH40470.1 - 0.27 11.0 3.1 0.54 10.1 0.2 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spectrin PF00435.16 KFH40470.1 - 0.97 9.7 6.6 1.1 9.5 2.3 2.4 2 1 0 2 2 1 0 Spectrin repeat FlxA PF14282.1 KFH40470.1 - 1.8 8.5 9.8 1.4 8.8 0.2 2.7 2 1 1 3 3 3 0 FlxA-like protein NPV_P10 PF05531.7 KFH40470.1 - 2.2 8.5 6.8 18 5.6 0.6 3.7 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Acetyltransf_7 PF13508.1 KFH40471.1 - 6e-09 35.9 0.0 1.1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFH40471.1 - 3.3e-06 27.0 0.1 5.8e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KFH40471.1 - 1.4e-05 24.9 0.0 2.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFH40471.1 - 0.00098 19.2 0.0 0.0024 18.0 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFH40471.1 - 0.0065 16.2 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 KFH40471.1 - 0.082 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Lon_C PF05362.8 KFH40472.1 - 4.2e-68 228.6 0.2 7.1e-68 227.9 0.2 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 KFH40472.1 - 3.1e-26 92.3 0.0 6.4e-26 91.2 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 KFH40472.1 - 1.3e-22 80.4 0.0 2.7e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFH40472.1 - 1.9e-08 34.1 0.0 7.4e-08 32.2 0.0 2.1 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 KFH40472.1 - 8.3e-08 31.7 0.7 3.7e-07 29.6 0.0 2.4 3 0 0 3 3 2 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.1 KFH40472.1 - 4.2e-06 26.8 0.0 1.4e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 KFH40472.1 - 2.2e-05 24.4 0.0 5.7e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_3 PF07726.6 KFH40472.1 - 2.6e-05 23.8 0.0 0.00011 21.8 0.0 2.1 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KFH40472.1 - 3.8e-05 23.1 0.0 0.00012 21.5 0.0 1.8 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 KFH40472.1 - 3.9e-05 24.4 0.0 0.00013 22.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KFH40472.1 - 0.00025 21.1 0.0 0.004 17.2 0.0 2.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KFH40472.1 - 0.00027 20.0 0.1 0.00099 18.2 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KFH40472.1 - 0.0016 18.3 0.0 0.0036 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFH40472.1 - 0.0016 18.1 0.0 0.0058 16.3 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 KFH40472.1 - 0.0017 18.2 0.0 0.0043 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 KFH40472.1 - 0.0059 16.2 0.1 0.011 15.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KFH40472.1 - 0.006 15.9 0.0 0.024 14.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KFH40472.1 - 0.006 15.3 0.2 0.025 13.3 0.0 1.9 2 0 0 2 2 2 1 TIP49 C-terminus RNA_helicase PF00910.17 KFH40472.1 - 0.015 15.4 0.0 0.062 13.4 0.0 2.1 2 0 0 2 2 1 0 RNA helicase Zeta_toxin PF06414.7 KFH40472.1 - 0.015 14.3 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.7 KFH40472.1 - 0.017 14.7 0.0 0.052 13.2 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 KFH40472.1 - 0.029 14.6 0.1 0.071 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KFH40472.1 - 0.034 12.9 0.0 0.061 12.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF258 PF03193.11 KFH40472.1 - 0.037 13.2 0.0 0.081 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 KFH40472.1 - 0.043 13.5 0.0 0.11 12.1 0.0 1.8 1 0 0 1 1 1 0 NTPase Mg_chelatase PF01078.16 KFH40472.1 - 0.046 12.8 0.1 0.11 11.5 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI UPF0079 PF02367.12 KFH40472.1 - 0.062 12.9 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 KFH40472.1 - 0.08 13.2 3.0 0.11 12.8 0.0 2.4 2 1 0 2 2 1 0 AAA domain MobB PF03205.9 KFH40472.1 - 0.085 12.5 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_PrkA PF08298.6 KFH40472.1 - 0.17 10.5 0.0 1.9 7.1 0.0 2.2 2 0 0 2 2 2 0 PrkA AAA domain C2 PF00168.25 KFH40474.1 - 6.3e-06 25.9 0.0 3.1e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 C2 domain Pkinase_C PF00433.19 KFH40474.1 - 0.00014 22.3 4.4 0.00023 21.6 0.2 3.3 2 2 0 2 2 2 1 Protein kinase C terminal domain ATP_sub_h PF10775.4 KFH40475.1 - 1.2e-24 85.7 1.9 2.5e-24 84.7 1.0 1.7 1 1 1 2 2 2 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 KFH40475.1 - 0.00085 19.1 0.1 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 LSM PF01423.17 KFH40476.1 - 0.00034 20.1 0.0 0.00038 19.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain Fe_hyd_lg_C PF02906.9 KFH40477.1 - 2.5e-61 207.4 0.0 7.4e-61 205.8 0.0 1.8 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain WD40 PF00400.27 KFH40478.1 - 4.3e-54 178.5 22.4 2.5e-12 46.1 1.3 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat PRP4 PF08799.6 KFH40478.1 - 9.3e-13 47.2 1.1 1.7e-12 46.3 0.7 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Nbas_N PF15492.1 KFH40478.1 - 0.0064 15.6 0.0 0.28 10.2 0.0 2.4 2 0 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal DUF4165 PF13752.1 KFH40478.1 - 0.13 12.0 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4165) Cyclin_N PF00134.18 KFH40479.1 - 2.5e-11 43.2 0.3 5e-11 42.2 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF3792 PF12670.2 KFH40480.1 - 0.0046 16.7 2.2 0.0068 16.2 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3792) DUF1691 PF07950.6 KFH40480.1 - 0.1 12.5 0.1 0.17 11.7 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1691) DUF4153 PF13687.1 KFH40480.1 - 0.11 12.0 1.2 0.2 11.1 0.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4153) IncA PF04156.9 KFH40480.1 - 1.1 8.8 2.9 15 5.1 0.1 2.4 2 1 0 2 2 2 0 IncA protein SUZ PF12752.2 KFH40481.1 - 0.00011 22.7 5.5 0.00011 22.7 3.8 3.6 3 2 0 3 3 3 1 SUZ domain SUZ-C PF12901.2 KFH40481.1 - 0.00018 21.0 3.3 0.00018 21.0 2.3 2.2 2 0 0 2 2 2 1 SUZ-C motif Synaphin PF05835.7 KFH40481.1 - 0.35 11.0 10.5 0.047 13.8 3.2 2.0 2 0 0 2 2 2 0 Synaphin protein DUF2782 PF11191.3 KFH40481.1 - 3.4 7.6 6.7 3.2 7.7 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2782) Sulfate_transp PF00916.15 KFH40482.1 - 3.3e-66 223.1 6.0 5.6e-66 222.3 4.2 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KFH40482.1 - 4.7e-29 99.8 4.8 4.7e-29 99.8 3.4 3.2 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KFH40482.1 - 1.3e-06 27.8 0.0 2.4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 KFH40482.1 - 0.0083 16.1 0.2 0.023 14.6 0.2 1.7 1 0 0 1 1 1 1 STAS domain DUF1189 PF06691.6 KFH40482.1 - 0.7 9.1 4.0 1.9 7.7 2.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) Glyco_transf_22 PF03901.12 KFH40483.1 - 7.8e-86 288.6 15.7 9.4e-86 288.4 10.9 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Peptidase_M28 PF04389.12 KFH40484.1 - 1.9e-25 89.6 0.0 4.3e-25 88.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KFH40484.1 - 0.0056 16.2 0.1 0.015 14.7 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Acetyltransf_7 PF13508.1 KFH40485.1 - 9.7e-05 22.4 0.0 0.0002 21.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFH40485.1 - 0.00015 21.7 0.3 0.00089 19.2 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KFH40485.1 - 0.00028 20.7 0.1 0.0012 18.6 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF3143 PF11341.3 KFH40485.1 - 0.0068 16.2 0.2 0.017 14.9 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3143) Acetyltransf_3 PF13302.1 KFH40485.1 - 0.027 14.6 0.6 0.37 10.9 0.0 2.5 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain RHS PF03527.9 KFH40485.1 - 0.071 12.8 0.1 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 RHS protein Fungal_trans_2 PF11951.3 KFH40486.1 - 0.0075 14.9 0.0 0.012 14.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KFH40487.1 - 4.9e-36 124.1 53.5 7.2e-36 123.6 34.9 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2681 PF10883.3 KFH40487.1 - 0.88 9.8 9.4 1 9.5 2.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF4407 PF14362.1 KFH40487.1 - 2.1 7.2 8.0 4.5 6.1 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) Sld5 PF05916.6 KFH40488.1 - 4.6e-25 88.0 0.0 7.1e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein DUF2605 PF10792.4 KFH40488.1 - 0.026 14.1 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) AAA_12 PF13087.1 KFH40490.1 - 5.4e-23 81.4 0.0 9.4e-23 80.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KFH40490.1 - 1.7e-09 37.6 0.0 0.00011 21.8 0.0 2.4 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.1 KFH40490.1 - 5.8e-06 26.0 0.8 0.0039 16.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KFH40490.1 - 4.3e-05 23.1 0.2 0.00044 19.9 0.1 2.4 2 0 0 2 2 2 1 Part of AAA domain Helicase_RecD PF05127.9 KFH40490.1 - 0.0033 17.0 0.1 0.39 10.3 0.0 3.0 3 0 0 3 3 3 1 Helicase Gar1 PF04410.9 KFH40491.1 - 3.9e-46 156.3 0.3 3.9e-46 156.3 0.2 2.0 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region Peptidase_M20 PF01546.23 KFH40492.1 - 7.1e-22 77.8 0.7 1.5e-21 76.7 0.2 1.7 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KFH40492.1 - 4.3e-21 74.7 0.0 6.7e-21 74.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KFH40492.1 - 0.00082 19.1 0.1 0.0013 18.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 Pkinase PF00069.20 KFH40493.1 - 1.6e-23 83.2 0.0 2e-23 82.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH40493.1 - 2.5e-15 56.2 0.0 3.2e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFH40493.1 - 0.00059 18.9 0.0 0.00086 18.4 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFH40493.1 - 0.0035 16.3 0.0 0.0073 15.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KFH40493.1 - 0.025 14.3 0.4 0.3 10.7 0.5 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family YchF-GTPase_C PF06071.8 KFH40493.1 - 0.048 13.4 0.2 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF933) WaaY PF06176.6 KFH40493.1 - 0.19 10.9 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Peptidase_C97 PF05903.9 KFH40494.1 - 1.3e-06 28.2 0.0 2.1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF4105 PF13387.1 KFH40494.1 - 0.011 14.9 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) LRAT PF04970.8 KFH40494.1 - 0.016 15.1 0.7 0.21 11.5 0.5 2.2 1 1 0 1 1 1 0 Lecithin retinol acyltransferase BNR PF02012.15 KFH40495.1 - 0.03 14.1 3.4 1.4 9.0 1.1 3.3 2 0 0 2 2 2 0 BNR/Asp-box repeat Peptidase_C69 PF03577.10 KFH40496.1 - 7.5e-25 87.6 0.0 1.1e-24 87.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C69 Cofilin_ADF PF00241.15 KFH40497.1 - 7.1e-15 55.0 0.0 8.3e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Diacid_rec PF05651.8 KFH40497.1 - 0.13 11.6 0.1 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative sugar diacid recognition HhH-GPD PF00730.20 KFH40498.1 - 2.6e-21 75.9 0.0 5.8e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 KFH40498.1 - 2.5e-15 55.8 0.0 5.6e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain HHH PF00633.18 KFH40498.1 - 0.004 16.7 0.1 0.011 15.4 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 KFH40498.1 - 0.037 14.1 0.0 0.29 11.3 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix domain PPDK_N PF01326.14 KFH40499.1 - 2.8e-90 302.6 0.0 4.8e-90 301.9 0.0 1.3 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers_C PF02896.13 KFH40499.1 - 4.3e-62 209.6 0.0 6.5e-62 209.0 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.18 KFH40499.1 - 1.6e-25 88.4 0.8 4.5e-25 87.0 0.6 1.8 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain p450 PF00067.17 KFH40500.1 - 1.2e-43 149.3 0.0 3.2e-43 147.9 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Allantoicase PF03561.10 KFH40501.1 - 4.1e-107 354.2 0.5 4e-57 191.9 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat DUF3248 PF11609.3 KFH40501.1 - 0.066 12.9 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3248) RabGAP-TBC PF00566.13 KFH40502.1 - 4.7e-34 117.7 0.0 1e-33 116.6 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MFS_1 PF07690.11 KFH40503.1 - 1.9e-36 125.5 34.8 1.9e-36 125.5 24.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily ketoacyl-synt PF00109.21 KFH40504.1 - 3.9e-80 268.9 0.0 1.1e-79 267.4 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Carn_acyltransf PF00755.15 KFH40504.1 - 1.1e-78 264.7 0.0 1.6e-78 264.3 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Acyl_transf_1 PF00698.16 KFH40504.1 - 3.2e-61 207.4 0.1 8.8e-61 205.9 0.1 1.7 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KFH40504.1 - 4.1e-50 170.6 0.7 4.1e-50 170.6 0.5 1.6 2 0 0 2 2 1 1 Polyketide synthase dehydratase KR PF08659.5 KFH40504.1 - 3e-47 160.6 0.1 9.3e-47 159.0 0.0 2.0 2 0 0 2 2 1 1 KR domain adh_short PF00106.20 KFH40504.1 - 1.5e-37 129.1 0.8 4.1e-37 127.6 0.0 2.3 3 0 0 3 3 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KFH40504.1 - 1.6e-27 95.7 1.4 4.3e-27 94.3 1.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KFH40504.1 - 1.6e-17 63.2 0.1 7.1e-17 61.1 0.0 2.2 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KFH40504.1 - 3.8e-16 59.3 0.0 1.1e-15 57.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KFH40504.1 - 1.7e-13 51.5 0.0 1.3e-12 48.6 0.0 2.6 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KFH40504.1 - 1.5e-10 41.0 0.0 3.2e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH40504.1 - 4.4e-09 36.8 0.0 1.3e-08 35.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH40504.1 - 8.5e-09 35.7 0.0 2.6e-08 34.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH40504.1 - 1.7e-07 30.9 0.0 5.1e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFH40504.1 - 4.5e-05 23.7 0.0 0.00018 21.7 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 KFH40504.1 - 6.9e-05 21.9 0.3 0.00017 20.6 0.2 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.20 KFH40504.1 - 0.00019 21.6 0.4 0.0042 17.3 0.1 2.6 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_26 PF13659.1 KFH40504.1 - 0.00024 21.1 0.0 0.00089 19.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFH40504.1 - 0.00062 18.9 0.0 0.0014 17.7 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Polysacc_synt_2 PF02719.10 KFH40504.1 - 0.053 12.4 0.0 0.099 11.5 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KFH40504.1 - 0.067 11.8 0.0 0.13 10.9 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NodS PF05401.6 KFH40504.1 - 0.15 11.4 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) PCMT PF01135.14 KFH40504.1 - 0.18 11.3 0.0 0.45 10.0 0.0 1.6 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DIL PF01843.14 KFH40505.1 - 5.2e-20 71.2 4.5 2.1e-13 50.0 0.2 2.8 3 0 0 3 3 3 2 DIL domain Ank_2 PF12796.2 KFH40505.1 - 3.3e-17 62.5 0.0 1.1e-16 60.9 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFH40505.1 - 2.2e-14 52.4 1.5 3.9e-05 23.2 0.0 4.6 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.1 KFH40505.1 - 1.4e-13 50.9 0.4 6.9e-06 26.4 0.1 4.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFH40505.1 - 3.8e-11 42.8 0.0 9.2e-08 32.1 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFH40505.1 - 6.8e-10 38.2 0.2 0.075 13.3 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ribosomal_L17 PF01196.14 KFH40506.1 - 8.5e-30 103.1 0.4 1.5e-29 102.3 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L17 DUF3365 PF11845.3 KFH40506.1 - 0.015 15.1 0.1 0.022 14.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) SUZ PF12752.2 KFH40507.1 - 4.2e-15 56.0 1.8 4.2e-15 56.0 1.2 3.4 3 0 0 3 3 3 1 SUZ domain R3H PF01424.17 KFH40507.1 - 7.8e-07 28.6 0.0 1.7e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 R3H domain ALAD PF00490.16 KFH40508.1 - 4e-118 394.0 0.0 4.9e-118 393.7 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase PPR_2 PF13041.1 KFH40509.1 - 2.8e-18 65.6 0.0 0.00012 21.9 0.0 5.7 5 1 1 6 6 6 3 PPR repeat family PPR PF01535.15 KFH40509.1 - 2.9e-07 30.0 0.0 1.7 8.7 0.0 4.7 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.1 KFH40509.1 - 1.4e-06 28.1 0.5 3.2 8.2 0.0 5.1 5 0 0 5 5 5 3 Pentatricopeptide repeat domain PPR_1 PF12854.2 KFH40509.1 - 1.8e-06 27.3 0.0 0.31 10.5 0.0 4.2 5 0 0 5 5 5 2 PPR repeat NYN PF01936.13 KFH40509.1 - 0.063 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 NYN domain Neisseria_TspB PF05616.8 KFH40509.1 - 0.15 10.4 2.0 0.26 9.6 1.4 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Hexapep PF00132.19 KFH40510.1 - 1.1e-11 43.6 17.1 9.4e-08 31.2 0.9 3.1 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 KFH40510.1 - 1.9e-11 43.7 0.1 4e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.1 KFH40510.1 - 3.4e-10 39.2 18.7 2.9e-05 23.5 0.8 2.3 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Zn_clus PF00172.13 KFH40510.1 - 8.7e-10 38.3 8.6 1.8e-09 37.3 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_11 PF13720.1 KFH40510.1 - 0.062 13.5 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 IRF PF00605.12 KFH40511.1 - 0.017 14.8 0.2 0.019 14.7 0.1 1.1 1 0 0 1 1 1 0 Interferon regulatory factor transcription factor JAB PF01398.16 KFH40512.1 - 3.9e-16 58.8 0.0 6.1e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KFH40512.1 - 4e-14 52.6 0.2 6.9e-14 51.9 0.1 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function zf-CCHC_3 PF13917.1 KFH40513.1 - 2.2e-10 40.0 0.6 3.9e-10 39.3 0.4 1.4 1 0 0 1 1 1 1 Zinc knuckle CtIP_N PF10482.4 KFH40513.1 - 0.065 13.0 1.1 0.12 12.1 0.8 1.4 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain RepB-RCR_reg PF10723.4 KFH40513.1 - 0.97 9.2 3.4 0.46 10.2 0.5 1.9 2 1 0 2 2 2 0 Replication regulatory protein RepB Peptidase_A17 PF05380.8 KFH40514.1 - 0.032 14.0 0.8 0.097 12.5 0.3 1.8 2 0 0 2 2 2 0 Pao retrotransposon peptidase DUF883 PF05957.8 KFH40514.1 - 2.7 8.4 16.5 2.4 8.6 3.6 3.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) cwf18 PF08315.7 KFH40515.1 - 5.9e-45 152.8 6.4 5.9e-45 152.8 4.4 1.8 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor DUF3585 PF12130.3 KFH40515.1 - 0.89 9.3 9.1 0.22 11.3 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3585) Pro_CA PF00484.14 KFH40518.1 - 6.1e-50 169.1 0.0 7.5e-50 168.8 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase P-mevalo_kinase PF04275.9 KFH40518.1 - 0.032 13.9 0.0 0.076 12.7 0.0 1.6 1 0 0 1 1 1 0 Phosphomevalonate kinase DUF3895 PF13034.1 KFH40518.1 - 0.034 13.6 0.1 0.055 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3895) DUF3636 PF12331.3 KFH40519.1 - 1.8e-28 99.0 0.1 3.2e-28 98.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) V_ATPase_I PF01496.14 KFH40519.1 - 0.088 10.6 2.3 0.12 10.1 1.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_TATA_bd PF12325.3 KFH40519.1 - 1.3 8.7 7.4 2.9 7.6 5.1 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Amidase PF01425.16 KFH40520.1 - 9.8e-70 235.5 0.3 4.9e-69 233.2 0.2 1.8 1 1 0 1 1 1 1 Amidase MFS_1 PF07690.11 KFH40521.1 - 5.6e-40 137.1 44.1 5.6e-40 137.1 30.6 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily CTP_transf_1 PF01148.15 KFH40523.1 - 1.9e-82 276.8 26.2 2.4e-82 276.4 18.2 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Na_K-ATPase PF00287.13 KFH40523.1 - 3.4 6.3 5.6 6.8 5.3 0.1 2.2 2 0 0 2 2 2 0 Sodium / potassium ATPase beta chain Peptidase_M28 PF04389.12 KFH40524.1 - 1.3e-16 60.8 0.0 2.2e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 KFH40524.1 - 6.4e-16 58.0 0.0 1e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 KFH40524.1 - 1.3e-08 34.3 0.3 6.8e-07 28.9 0.0 2.4 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 KFH40524.1 - 0.00021 20.8 0.0 0.00039 19.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.10 KFH40524.1 - 0.14 11.3 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 Nicastrin E1-E2_ATPase PF00122.15 KFH40525.1 - 1.8e-63 213.6 2.5 3.2e-63 212.8 1.7 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFH40525.1 - 4.3e-34 117.6 1.3 4.3e-34 117.6 0.9 2.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFH40525.1 - 4.2e-27 95.9 0.1 4.8e-22 79.4 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFH40525.1 - 1.3e-19 69.9 0.0 3.7e-19 68.4 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KFH40525.1 - 3e-15 55.4 0.0 8.4e-15 53.9 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KFH40525.1 - 1.3e-12 48.3 0.0 2.6e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFH40525.1 - 7.4e-08 32.2 0.3 1.4e-05 24.7 0.3 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF3733 PF12534.3 KFH40525.1 - 0.1 11.9 0.1 0.38 10.0 0.1 1.9 1 0 0 1 1 1 0 Leucine-rich repeat containing protein 8 AAA_12 PF13087.1 KFH40526.1 - 7.7e-20 71.1 0.0 1.4e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KFH40526.1 - 5.9e-08 32.5 0.0 2.8e-07 30.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFH40526.1 - 1.7e-06 27.7 0.1 0.00012 21.7 0.1 3.6 3 0 0 3 3 3 1 Part of AAA domain AAA_30 PF13604.1 KFH40526.1 - 0.00046 19.8 0.3 1.5 8.3 0.0 2.9 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.13 KFH40526.1 - 0.021 14.3 0.0 6.3 6.2 0.0 3.1 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 KFH40526.1 - 0.044 12.7 0.0 0.095 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) zf-C2H2 PF00096.21 KFH40527.1 - 2.4e-21 74.7 47.6 0.00057 20.0 1.1 7.8 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFH40527.1 - 2.4e-18 65.4 47.4 1.5e-05 25.0 0.2 8.8 8 0 0 8 8 8 5 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFH40527.1 - 5.8e-15 54.4 44.1 0.0051 17.0 0.5 7.9 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFH40527.1 - 0.00025 21.0 25.6 0.046 13.8 0.4 7.2 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding Ogr_Delta PF04606.7 KFH40527.1 - 0.1 12.2 13.7 0.94 9.1 1.8 4.1 2 2 2 4 4 4 0 Ogr/Delta-like zinc finger Tropomyosin PF00261.15 KFH40528.1 - 0.011 14.8 3.2 0.017 14.2 2.2 1.3 1 0 0 1 1 1 0 Tropomyosin AAA_13 PF13166.1 KFH40528.1 - 0.011 14.1 0.3 0.013 13.9 0.2 1.1 1 0 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.7 KFH40528.1 - 0.017 14.9 0.9 0.029 14.2 0.6 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.8 KFH40528.1 - 1.3 9.4 9.3 0.64 10.4 3.8 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) HA2 PF04408.18 KFH40529.1 - 6.5e-26 90.3 0.0 2.7e-25 88.3 0.0 2.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KFH40529.1 - 1.3e-25 89.4 0.0 3.2e-24 84.9 0.0 2.7 3 0 0 3 3 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KFH40529.1 - 7.9e-13 48.0 0.0 2.2e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFH40529.1 - 3.4e-06 26.6 0.0 8.9e-06 25.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KFH40529.1 - 6.9e-06 26.2 0.1 2.2e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 KFH40529.1 - 0.00025 20.9 0.0 0.12 12.1 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SE PF00437.15 KFH40529.1 - 0.0017 17.2 0.0 0.0044 15.9 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.9 KFH40529.1 - 0.0022 17.7 0.1 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain SRP54 PF00448.17 KFH40529.1 - 0.0028 17.1 0.0 0.0059 16.0 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Arch_ATPase PF01637.13 KFH40529.1 - 0.007 16.0 1.2 0.012 15.3 0.0 1.9 2 0 0 2 2 2 1 Archaeal ATPase AAA_14 PF13173.1 KFH40529.1 - 0.01 15.7 0.3 0.078 12.8 0.2 2.3 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KFH40529.1 - 0.015 15.6 1.7 0.026 14.8 0.0 2.3 2 0 0 2 2 1 0 AAA domain AAA_29 PF13555.1 KFH40529.1 - 0.02 14.4 0.0 0.043 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KFH40529.1 - 0.023 15.0 0.2 0.11 12.8 0.0 2.2 2 0 0 2 2 2 0 ABC transporter GAD PF02938.9 KFH40529.1 - 0.024 14.7 0.0 0.065 13.3 0.0 1.7 1 0 0 1 1 1 0 GAD domain TrwB_AAD_bind PF10412.4 KFH40529.1 - 0.031 12.9 0.1 0.055 12.0 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain KaiC PF06745.8 KFH40529.1 - 0.046 12.8 0.0 0.097 11.7 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.1 KFH40529.1 - 0.055 12.8 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KFH40529.1 - 0.058 12.8 0.1 8.9 5.6 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain zf-UDP PF14569.1 KFH40530.1 - 0.48 10.2 7.2 1.1 9.0 5.0 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger C1_3 PF07649.7 KFH40530.1 - 2.2 8.4 9.0 5.4 7.1 6.3 1.7 1 0 0 1 1 1 0 C1-like domain ChaC PF04752.7 KFH40532.1 - 1.1e-35 123.2 0.0 1.8e-35 122.5 0.0 1.3 1 1 0 1 1 1 1 ChaC-like protein WD40 PF00400.27 KFH40534.1 - 1.5e-25 88.1 8.0 4.6e-08 32.6 0.1 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 KFH40534.1 - 0.00028 19.1 0.4 0.0023 16.1 0.9 2.1 2 1 1 3 3 3 1 Nucleoporin Nup120/160 HpcH_HpaI PF03328.9 KFH40535.1 - 2.1e-41 141.2 0.1 3.5e-40 137.2 0.0 2.0 2 0 0 2 2 2 2 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 KFH40535.1 - 4.6e-11 42.1 0.0 1.3e-07 30.7 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Hep_59 PF07052.6 KFH40537.1 - 1.4e-06 28.6 3.0 1.4e-06 28.5 0.0 2.3 2 1 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 SPACA7 PF15307.1 KFH40537.1 - 0.053 13.6 0.1 0.41 10.8 0.0 2.1 2 0 0 2 2 2 0 Sperm acrosome-associated protein 7 Lactamase_B_3 PF13483.1 KFH40538.1 - 2.2e-07 30.7 0.1 5e-07 29.5 0.0 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RRM_1 PF00076.17 KFH40539.1 - 6.2e-24 83.4 0.0 8.2e-24 83.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH40539.1 - 7.2e-16 57.9 0.0 9.5e-16 57.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH40539.1 - 8e-10 38.4 0.0 1.1e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFH40539.1 - 0.042 13.6 0.1 0.063 13.1 0.1 1.3 1 0 0 1 1 1 0 RNA binding motif GRP PF07172.6 KFH40539.1 - 0.74 10.3 12.0 1.2 9.6 8.3 1.4 1 0 0 1 1 1 0 Glycine rich protein family EF-hand_1 PF00036.27 KFH40540.1 - 3.4e-26 88.4 10.2 8.4e-07 27.8 0.1 5.4 5 1 0 5 5 5 5 EF hand EF-hand_7 PF13499.1 KFH40540.1 - 1.3e-23 82.9 7.0 4.1e-09 36.4 0.1 3.4 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 KFH40540.1 - 1.6e-21 74.2 9.5 0.00014 21.4 0.2 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 KFH40540.1 - 5.3e-19 67.5 12.1 7.5e-08 31.8 0.1 4.5 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.1 KFH40540.1 - 3.5e-17 60.8 11.5 0.00023 20.3 0.5 4.5 4 0 0 4 4 4 4 EF hand DIOX_N PF14226.1 KFH40543.1 - 3.2e-18 66.3 0.0 5.9e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KFH40543.1 - 1.4e-12 47.7 0.0 2.2e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Lactonase PF10282.4 KFH40544.1 - 2.3e-78 263.6 0.0 3.2e-78 263.2 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller PPC PF04151.10 KFH40544.1 - 6.2 7.8 9.6 5.4 8.0 0.2 3.9 3 2 1 4 4 4 0 Bacterial pre-peptidase C-terminal domain GMC_oxred_N PF00732.14 KFH40546.1 - 2.6e-54 184.3 0.0 3.6e-54 183.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFH40546.1 - 5.2e-33 114.3 0.0 8e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DIOX_N PF14226.1 KFH40547.1 - 1.1e-27 96.9 0.0 1.9e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KFH40547.1 - 9.3e-16 57.9 0.0 1.8e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Trypsin PF00089.21 KFH40548.1 - 4.4e-10 39.5 0.0 6.8e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 KFH40548.1 - 0.00084 19.3 0.0 0.0022 17.9 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain AMP_N PF05195.11 KFH40548.1 - 0.092 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain DUF481 PF04338.7 KFH40549.1 - 0.056 13.1 0.6 0.093 12.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF481 FA_desaturase PF00487.19 KFH40550.1 - 8.8e-13 48.2 32.5 3e-12 46.5 22.1 1.9 1 1 1 2 2 2 1 Fatty acid desaturase NAD_binding_1 PF00175.16 KFH40551.1 - 2.6e-10 40.8 0.0 6.3e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.17 KFH40551.1 - 1.2e-08 35.2 0.2 5.7e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 Globin FAD_binding_6 PF00970.19 KFH40551.1 - 6.5e-08 32.6 0.0 1.1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KFH40551.1 - 0.00022 21.1 0.0 0.0007 19.5 0.0 1.8 2 1 0 2 2 2 1 Ferric reductase NAD binding domain Protoglobin PF11563.3 KFH40551.1 - 0.00041 20.0 0.0 0.00069 19.2 0.0 1.4 1 0 0 1 1 1 1 Protoglobin MFS_1 PF07690.11 KFH40553.1 - 4.5e-21 74.9 39.0 4.5e-21 74.9 27.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 KFH40553.1 - 3.9e-07 28.9 6.4 3.9e-07 28.9 4.4 2.5 1 1 1 2 2 2 1 Vacuole effluxer Atg22 like Aldedh PF00171.17 KFH40554.1 - 4.3e-06 25.3 0.0 5.1e-06 25.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family p450 PF00067.17 KFH40555.1 - 5.2e-60 203.2 0.0 6.9e-60 202.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CorA PF01544.13 KFH40557.1 - 0.0047 16.0 0.3 0.0056 15.7 0.2 1.2 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Benyvirus_14KDa PF07255.6 KFH40557.1 - 0.022 14.6 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Benyvirus 14KDa protein Sulfotransfer_3 PF13469.1 KFH40558.1 - 6.1e-06 27.2 2.1 8.3e-06 26.8 1.0 1.5 1 1 0 1 1 1 1 Sulfotransferase family Methyltransf_18 PF12847.2 KFH40559.1 - 7.8e-12 45.7 0.3 2.8e-11 43.9 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH40559.1 - 2.9e-09 37.2 0.0 4.2e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH40559.1 - 3.8e-08 33.7 0.0 6e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH40559.1 - 2e-07 30.7 0.0 2.6e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH40559.1 - 1.2e-05 25.1 0.0 1.4e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 KFH40559.1 - 0.00011 22.1 0.0 0.00018 21.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_26 PF13659.1 KFH40559.1 - 0.00022 21.2 0.1 0.00043 20.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 KFH40559.1 - 0.0064 15.6 0.0 0.015 14.4 0.0 1.5 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_25 PF13649.1 KFH40559.1 - 0.0078 16.5 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFH40559.1 - 0.0092 15.3 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.4 KFH40559.1 - 0.013 14.9 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.15 KFH40559.1 - 0.046 12.8 0.0 0.06 12.4 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase adh_short_C2 PF13561.1 KFH40559.1 - 0.052 13.3 0.0 0.072 12.8 0.0 1.1 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase APH PF01636.18 KFH40560.1 - 1.1e-05 25.3 0.4 1.4e-05 24.9 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KFH40560.1 - 0.033 13.2 0.1 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.15 KFH40560.1 - 0.16 11.1 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase VSP PF03302.8 KFH40561.1 - 0.031 12.9 6.6 0.031 12.9 3.5 1.7 1 1 1 2 2 2 0 Giardia variant-specific surface protein Asp PF00026.18 KFH40561.1 - 0.043 13.0 0.0 0.33 10.1 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic aspartyl protease Transferase PF02458.10 KFH40562.1 - 2.3e-27 95.5 0.0 3.8e-18 65.1 0.0 2.2 2 1 0 2 2 2 2 Transferase family Epimerase PF01370.16 KFH40563.1 - 7e-25 87.8 0.0 1.1e-24 87.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFH40563.1 - 3.8e-15 55.3 0.0 4.7e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KFH40563.1 - 4.6e-14 51.9 0.0 7.9e-13 47.9 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KFH40563.1 - 9.2e-14 51.8 0.3 4.4e-12 46.3 0.2 2.2 1 1 1 2 2 2 2 NADH(P)-binding Polysacc_synt_2 PF02719.10 KFH40563.1 - 6.3e-10 38.4 0.1 8.8e-10 37.9 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KFH40563.1 - 3.8e-09 36.6 0.1 7.1e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH40563.1 - 1.4e-05 24.8 0.0 2.5e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 KFH40563.1 - 0.00029 21.2 0.2 0.00071 19.9 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.8 KFH40563.1 - 0.00045 19.5 0.2 0.0042 16.3 0.2 2.4 2 1 1 3 3 3 1 NmrA-like family DapB_N PF01113.15 KFH40563.1 - 0.0087 15.9 0.1 0.015 15.2 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_2 PF03446.10 KFH40563.1 - 0.021 14.6 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 KFH40563.1 - 0.024 14.3 0.3 0.048 13.3 0.2 1.6 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 KFH40563.1 - 0.025 13.5 0.1 0.034 13.1 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 KFH40563.1 - 0.026 14.8 0.3 0.16 12.2 0.1 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 KFH40563.1 - 0.073 11.9 0.3 0.12 11.2 0.2 1.6 1 1 0 1 1 1 0 RmlD substrate binding domain HET PF06985.6 KFH40564.1 - 1.2e-36 125.8 4.0 2.1e-36 125.1 2.8 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.17 KFH40566.1 - 1.3e-51 175.6 0.0 1.5e-51 175.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LSM PF01423.17 KFH40567.1 - 3e-18 65.1 0.0 3.9e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.1 KFH40567.1 - 0.019 15.3 6.8 0.039 14.4 4.7 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 GAT PF03127.9 KFH40568.1 - 8.6e-18 64.1 4.2 9.1e-18 64.1 0.7 2.3 2 1 0 2 2 2 1 GAT domain VHS PF00790.14 KFH40568.1 - 1.8e-05 24.3 0.0 4.6e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 VHS domain PspA_IM30 PF04012.7 KFH40568.1 - 0.016 14.6 0.9 0.082 12.2 0.6 1.9 1 1 0 1 1 1 0 PspA/IM30 family Pkinase PF00069.20 KFH40569.1 - 1.6e-06 27.4 0.0 3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KFH40569.1 - 0.00062 18.8 0.0 0.0013 17.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-CCCH PF00642.19 KFH40569.1 - 0.011 15.3 0.7 0.02 14.5 0.5 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF2247 PF10004.4 KFH40569.1 - 0.04 13.6 0.1 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) PAM2 PF07145.10 KFH40569.1 - 0.32 10.5 1.4 6 6.6 0.0 2.7 2 0 0 2 2 2 0 Ataxin-2 C-terminal region E1-E2_ATPase PF00122.15 KFH40570.1 - 2.3e-65 219.8 1.6 2.3e-65 219.8 1.1 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KFH40570.1 - 8e-31 108.1 0.0 1.3e-29 104.1 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 KFH40570.1 - 8.8e-31 106.8 9.7 8.8e-31 106.8 6.8 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 KFH40570.1 - 2.8e-17 62.4 0.0 5.8e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KFH40570.1 - 1.6e-16 59.4 0.7 4.1e-16 58.2 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KFH40570.1 - 3.1e-15 56.8 0.0 6.8e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFH40570.1 - 0.13 11.7 0.1 0.49 9.9 0.1 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase UBA_4 PF14555.1 KFH40573.1 - 5.6e-12 44.9 0.0 1.3e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 KFH40573.1 - 1.9e-08 34.2 0.0 4.2e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 UBX domain SUFU_C PF12470.3 KFH40573.1 - 0.029 13.9 0.2 0.045 13.3 0.1 1.3 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain WPP PF13943.1 KFH40573.1 - 0.53 10.5 0.0 0.53 10.5 0.0 2.7 2 1 1 3 3 3 0 WPP domain TrwC PF08751.6 KFH40573.1 - 6.7 6.0 10.1 12 5.2 7.0 1.3 1 0 0 1 1 1 0 TrwC relaxase Trypan_PARP PF05887.6 KFH40574.1 - 7.6 6.3 15.3 0.81 9.4 7.3 1.8 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) Neisseria_TspB PF05616.8 KFH40574.1 - 9.9 4.4 7.0 12 4.0 4.9 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Cupin_5 PF06172.6 KFH40575.1 - 6.4e-34 116.8 0.1 3.8e-31 107.8 0.1 2.1 1 1 0 1 1 1 1 Cupin superfamily (DUF985) Sporozoite_P67 PF05642.6 KFH40575.1 - 0.0037 15.2 0.6 0.004 15.0 0.4 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen TEX19 PF15553.1 KFH40575.1 - 0.046 13.5 1.2 0.06 13.2 0.8 1.3 1 0 0 1 1 1 0 Testis-expressed protein 19 Usp PF00582.21 KFH40575.1 - 0.17 12.0 1.9 0.26 11.4 1.3 1.4 1 0 0 1 1 1 0 Universal stress protein family VID27 PF08553.5 KFH40575.1 - 0.18 9.9 8.3 0.22 9.6 5.7 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein HSP90 PF00183.13 KFH40575.1 - 0.19 10.0 8.7 0.22 9.8 6.0 1.0 1 0 0 1 1 1 0 Hsp90 protein DUF2890 PF11081.3 KFH40575.1 - 0.23 11.4 11.1 0.32 11.0 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Ycf1 PF05758.7 KFH40575.1 - 0.34 8.5 1.1 0.36 8.5 0.7 1.0 1 0 0 1 1 1 0 Ycf1 CDC45 PF02724.9 KFH40575.1 - 0.75 7.7 6.7 0.92 7.4 4.6 1.1 1 0 0 1 1 1 0 CDC45-like protein YqfQ PF14181.1 KFH40575.1 - 1.4 8.9 6.3 2.2 8.2 4.4 1.3 1 0 0 1 1 1 0 YqfQ-like protein Nop14 PF04147.7 KFH40575.1 - 2.2 6.0 14.3 2.8 5.7 9.9 1.0 1 0 0 1 1 1 0 Nop14-like family Paf1 PF03985.8 KFH40575.1 - 2.2 6.9 14.3 2.9 6.5 9.9 1.1 1 0 0 1 1 1 0 Paf1 SspB PF04386.8 KFH40575.1 - 2.5 7.6 6.3 3.5 7.2 4.4 1.2 1 0 0 1 1 1 0 Stringent starvation protein B NOA36 PF06524.7 KFH40575.1 - 2.7 7.1 7.0 3.5 6.7 4.8 1.1 1 0 0 1 1 1 0 NOA36 protein CobT PF06213.7 KFH40575.1 - 2.8 6.9 12.8 3.8 6.5 8.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF3381 PF11861.3 KFH40575.1 - 2.8 7.4 12.9 3.9 6.9 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) XAP5 PF04921.9 KFH40575.1 - 3 7.3 6.2 3.9 6.9 4.3 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator Sigma70_ner PF04546.8 KFH40575.1 - 4.7 6.7 12.9 6.5 6.3 8.9 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Daxx PF03344.10 KFH40575.1 - 5.8 5.2 18.2 7.2 4.9 12.6 1.1 1 0 0 1 1 1 0 Daxx Family TRAP_alpha PF03896.11 KFH40575.1 - 8.2 5.3 9.4 11 4.9 6.5 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Zn_clus PF00172.13 KFH40577.1 - 0.00045 20.0 10.4 0.00081 19.2 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.2 KFH40578.1 - 1.7e-34 117.9 0.1 3.5e-08 33.6 0.5 6.0 3 3 1 5 5 5 5 Ankyrin repeats (3 copies) Pkinase PF00069.20 KFH40578.1 - 3.9e-21 75.3 0.0 6.3e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank PF00023.25 KFH40578.1 - 5.9e-20 70.0 15.8 1.1e-05 25.0 0.4 10.5 11 0 0 11 11 11 4 Ankyrin repeat Ank_4 PF13637.1 KFH40578.1 - 1.6e-18 66.6 5.0 3e-07 30.7 0.1 6.4 6 1 1 7 7 7 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFH40578.1 - 1.6e-17 63.1 9.0 4.2e-06 26.8 0.2 6.6 7 0 0 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFH40578.1 - 6.1e-16 56.9 7.6 0.00016 21.5 0.1 9.2 9 0 0 9 9 9 3 Ankyrin repeat Pkinase_Tyr PF07714.12 KFH40578.1 - 2.7e-14 52.8 0.0 4.5e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KFH40578.1 - 0.34 9.6 0.0 0.52 9.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase LysM PF01476.15 KFH40579.1 - 1.7e-05 24.5 0.0 3.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 LysM domain HeLo PF14479.1 KFH40580.1 - 5.2e-22 78.6 0.9 5.2e-22 78.6 0.6 2.1 3 0 0 3 3 3 1 Prion-inhibition and propagation Pkinase PF00069.20 KFH40580.1 - 0.002 17.3 0.0 0.012 14.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain p450 PF00067.17 KFH40582.1 - 1.3e-44 152.4 0.0 1.7e-44 152.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Myb_CC_LHEQLE PF14379.1 KFH40582.1 - 0.037 13.5 0.3 0.098 12.2 0.2 1.7 1 0 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif MIF4G PF02854.14 KFH40583.1 - 4.9e-53 179.6 0.0 7.5e-53 179.0 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 KFH40583.1 - 1.8e-21 75.8 1.0 4.7e-21 74.4 0.7 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Eno-Rase_FAD_bd PF07055.7 KFH40583.1 - 0.032 14.1 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain eIF-5_eIF-2B PF01873.12 KFH40585.1 - 1.3e-40 137.9 0.1 4.4e-40 136.2 0.0 1.9 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.13 KFH40585.1 - 2e-22 78.9 0.4 6.1e-22 77.3 0.3 1.9 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon DNA_pol_B PF00136.16 KFH40586.1 - 4.8e-112 375.1 1.8 6.8e-112 374.6 1.3 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 KFH40586.1 - 8.4e-67 224.1 0.0 1.7e-66 223.1 0.0 1.6 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 KFH40586.1 - 3.9e-44 150.8 0.1 8.8e-44 149.6 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 KFH40586.1 - 1e-24 86.1 10.8 6.1e-24 83.6 7.5 2.5 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal AAA_11 PF13086.1 KFH40587.1 - 1.1e-23 84.0 0.0 2.4e-23 82.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.1 KFH40587.1 - 6.4e-22 77.9 0.0 1.3e-21 76.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFH40587.1 - 2e-09 37.0 0.0 1.4e-08 34.4 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KFH40587.1 - 4.7e-06 26.3 0.6 0.0052 16.3 0.0 2.9 3 0 0 3 3 3 2 AAA domain ResIII PF04851.10 KFH40587.1 - 2.3e-05 24.2 0.0 4.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA PF00004.24 KFH40587.1 - 0.0029 17.8 0.0 0.0066 16.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFH40587.1 - 0.0035 17.3 0.0 0.015 15.3 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain DEAD PF00270.24 KFH40587.1 - 0.0044 16.5 0.0 0.022 14.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_25 PF13481.1 KFH40587.1 - 0.0048 16.3 0.1 0.018 14.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KFH40587.1 - 0.0079 16.3 0.0 0.022 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFH40587.1 - 0.012 14.7 0.0 0.028 13.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 KFH40587.1 - 0.013 16.2 0.0 0.81 10.5 0.0 3.3 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 KFH40587.1 - 0.022 13.7 0.0 0.038 12.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DnaB_C PF03796.10 KFH40587.1 - 0.061 12.2 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain NB-ARC PF00931.17 KFH40587.1 - 0.085 11.6 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 KFH40587.1 - 0.16 12.1 0.0 0.43 10.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PIF1 PF05970.9 KFH40587.1 - 0.16 10.8 0.0 11 4.8 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase efThoc1 PF11957.3 KFH40588.1 - 3e-145 484.4 1.0 4.1e-145 484.0 0.7 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.16 KFH40588.1 - 1.9e-33 115.4 0.0 3.3e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.1 KFH40588.1 - 2.8e-05 24.4 0.0 0.00027 21.2 0.0 2.8 2 1 0 2 2 1 1 AAA domain AAA_28 PF13521.1 KFH40588.1 - 0.00012 22.0 0.0 0.00031 20.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFH40588.1 - 0.00022 21.2 0.0 0.00064 19.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KFH40588.1 - 0.00023 21.9 0.0 0.0013 19.5 0.0 2.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 KFH40588.1 - 0.00025 20.9 0.0 0.00086 19.2 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 KFH40588.1 - 0.00035 20.4 0.0 0.0009 19.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 KFH40588.1 - 0.00046 19.4 0.0 0.00084 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 NTPase_1 PF03266.10 KFH40588.1 - 0.00092 18.9 0.1 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 NTPase AAA_22 PF13401.1 KFH40588.1 - 0.0012 18.9 0.0 0.003 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 KFH40588.1 - 0.0086 14.8 0.0 0.015 14.0 0.0 1.3 1 0 0 1 1 1 1 ArgK protein AAA_14 PF13173.1 KFH40588.1 - 0.0099 15.7 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFH40588.1 - 0.013 15.2 0.0 0.037 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 KFH40588.1 - 0.014 15.7 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 KFH40588.1 - 0.016 14.7 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.12 KFH40588.1 - 0.018 14.4 0.0 0.044 13.2 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.7 KFH40588.1 - 0.018 14.7 0.0 0.044 13.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain cobW PF02492.14 KFH40588.1 - 0.025 14.0 0.1 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 KFH40588.1 - 0.025 14.3 0.0 0.063 13.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Viral_helicase1 PF01443.13 KFH40588.1 - 0.025 14.0 0.0 0.055 12.9 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA PF00004.24 KFH40588.1 - 0.026 14.7 0.0 0.061 13.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KFH40588.1 - 0.027 13.5 0.0 0.061 12.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Miro PF08477.8 KFH40588.1 - 0.03 14.8 0.0 0.075 13.5 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein RNA_helicase PF00910.17 KFH40588.1 - 0.035 14.2 0.0 0.098 12.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 KFH40588.1 - 0.039 13.3 0.0 0.14 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KFH40588.1 - 0.062 12.7 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain NB-ARC PF00931.17 KFH40588.1 - 0.067 12.0 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain MobB PF03205.9 KFH40588.1 - 0.068 12.8 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 KFH40588.1 - 0.075 12.5 0.1 2.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein P5CR_dimer PF14748.1 KFH40589.1 - 3.9e-35 120.0 0.8 3.9e-35 120.0 0.6 1.9 2 1 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KFH40589.1 - 9.5e-19 67.6 1.8 9.5e-19 67.6 1.2 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 KFH40589.1 - 2.9e-05 23.8 5.1 0.00013 21.6 2.0 2.4 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 KFH40589.1 - 0.001 18.9 0.1 0.0017 18.2 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.1 KFH40589.1 - 0.015 15.5 0.1 0.042 14.1 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Semialdhyde_dh PF01118.19 KFH40589.1 - 0.076 13.3 0.3 0.18 12.1 0.1 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain SAB PF04382.8 KFH40590.1 - 0.034 13.8 0.2 0.12 12.1 0.1 1.9 1 0 0 1 1 1 0 SAB domain Nop16 PF09420.5 KFH40590.1 - 4.6 7.3 12.1 54 3.8 8.2 2.2 1 1 0 1 1 1 0 Ribosome biogenesis protein Nop16 DUF563 PF04577.9 KFH40592.1 - 1.2e-29 103.7 0.0 2.1e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) SnoaL PF07366.7 KFH40593.1 - 0.00025 20.5 0.1 0.00082 18.9 0.0 1.9 3 0 0 3 3 3 1 SnoaL-like polyketide cyclase SLT PF01464.15 KFH40595.1 - 5.2e-13 48.5 0.0 8.4e-13 47.8 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase SLT domain Bys1 PF04681.7 KFH40596.1 - 1.3e-12 47.6 0.0 1.6e-12 47.4 0.0 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein GED PF02212.13 KFH40598.1 - 0.075 12.9 1.2 0.15 11.9 0.3 1.7 2 0 0 2 2 2 0 Dynamin GTPase effector domain Vps39_2 PF10367.4 KFH40599.1 - 2.1e-06 27.8 0.0 5.4e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 KFH40599.1 - 0.026 14.5 0.0 0.22 11.5 0.0 2.3 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 PS_Dcarbxylase PF02666.10 KFH40600.1 - 1.7e-81 272.3 0.0 1.7e-80 269.0 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.1 KFH40600.1 - 0.23 11.1 1.1 0.48 10.1 0.5 1.7 2 0 0 2 2 2 0 Biotin-lipoyl like FAD_binding_1 PF00667.15 KFH40601.1 - 4.6e-42 143.9 0.0 8.6e-42 143.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KFH40601.1 - 8.4e-10 39.1 0.0 2.6e-09 37.6 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF3455 PF11937.3 KFH40603.1 - 4.3e-41 140.7 0.1 5.9e-41 140.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Methyltransf_16 PF10294.4 KFH40604.1 - 5e-12 45.6 0.0 1.9e-07 30.7 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase PrmA PF06325.8 KFH40604.1 - 0.0021 17.2 0.0 0.0029 16.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 KFH40604.1 - 0.024 15.1 0.0 0.044 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain zf-C2H2_4 PF13894.1 KFH40605.1 - 6.6e-05 22.9 15.1 0.11 12.8 0.0 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KFH40605.1 - 6.6e-05 23.0 18.8 1.3 9.5 0.3 5.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type DUF230 PF03003.11 KFH40605.1 - 0.011 15.2 0.2 0.023 14.2 0.1 1.5 1 0 0 1 1 1 0 Poxvirus proteins of unknown function DUF629 PF04780.7 KFH40605.1 - 0.031 12.8 0.1 0.25 9.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-H2C2_2 PF13465.1 KFH40605.1 - 0.68 10.3 17.8 0.92 9.9 0.6 4.8 4 1 0 4 4 4 0 Zinc-finger double domain DUF2407 PF10302.4 KFH40606.1 - 3.4e-05 23.9 0.1 0.00037 20.6 0.0 2.3 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 KFH40606.1 - 0.00013 21.3 0.0 0.00022 20.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.1 KFH40606.1 - 0.054 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_L22 PF00237.14 KFH40607.1 - 2.7e-33 114.0 0.1 3.6e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e CASP_C PF08172.7 KFH40608.1 - 1.8e-91 305.6 0.0 1.8e-91 305.6 0.0 3.6 2 1 1 3 3 3 1 CASP C terminal bZIP_2 PF07716.10 KFH40608.1 - 0.016 14.9 5.9 0.016 14.9 4.1 8.6 9 1 0 9 9 9 0 Basic region leucine zipper Fibrillarin PF01269.12 KFH40609.1 - 2.1e-101 337.6 0.0 2.6e-101 337.3 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 KFH40609.1 - 5e-07 29.4 0.0 7.7e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 KFH40609.1 - 0.0043 16.6 0.1 0.0066 16.0 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 2-Hacid_dh_C PF02826.14 KFH40610.1 - 1e-44 151.8 0.0 1.4e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFH40610.1 - 2.2e-05 23.9 0.0 2.8e-05 23.5 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.1 KFH40610.1 - 0.035 14.4 0.0 0.28 11.4 0.0 2.1 2 0 0 2 2 2 0 XdhC Rossmann domain AdoHcyase_NAD PF00670.16 KFH40610.1 - 0.063 13.1 0.0 0.21 11.4 0.0 1.8 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ELFV_dehydrog PF00208.16 KFH40610.1 - 0.09 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Scytalone_dh PF02982.9 KFH40611.1 - 3.9e-44 150.0 0.1 4.5e-44 149.8 0.0 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 KFH40611.1 - 1.3e-07 31.5 0.0 1.8e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Xan_ur_permease PF00860.15 KFH40612.1 - 5.9e-25 87.5 31.2 2.8e-15 55.7 8.9 2.9 3 0 0 3 3 3 2 Permease family Sulfate_transp PF00916.15 KFH40612.1 - 1.3e-05 24.3 6.0 0.00045 19.3 3.0 2.5 1 1 1 2 2 2 2 Sulfate transporter family Ank_5 PF13857.1 KFH40613.1 - 1.1e-11 44.4 0.5 0.00031 20.8 0.0 4.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KFH40613.1 - 1.2e-10 41.5 0.0 1.4e-06 28.5 0.0 3.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFH40613.1 - 2.1e-10 40.8 0.6 1.4e-05 25.4 0.1 4.4 3 1 1 4 4 4 1 Ankyrin repeats (many copies) NACHT PF05729.7 KFH40613.1 - 1.6e-09 37.6 0.1 4.1e-09 36.2 0.1 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KFH40613.1 - 4e-08 33.4 0.0 1.7e-07 31.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFH40613.1 - 3.2e-06 27.2 0.2 2.3e-05 24.4 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain Ank_3 PF13606.1 KFH40613.1 - 1.7e-05 24.5 0.0 0.94 9.9 0.0 5.8 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.25 KFH40613.1 - 5.1e-05 22.8 2.4 4.4 7.3 0.0 5.8 6 0 0 6 6 6 2 Ankyrin repeat TrwB_AAD_bind PF10412.4 KFH40613.1 - 0.03 12.9 0.0 0.077 11.6 0.0 1.6 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain KAP_NTPase PF07693.9 KFH40613.1 - 0.073 12.0 0.0 0.15 11.0 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain 2OG-FeII_Oxy PF03171.15 KFH40616.1 - 0.0011 19.2 0.0 0.0019 18.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KFH40616.1 - 0.0019 18.7 0.0 0.0031 18.0 0.0 1.5 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Rhomboid PF01694.17 KFH40619.1 - 1.1e-15 57.9 13.2 1.1e-15 57.9 9.1 2.0 1 1 1 2 2 2 1 Rhomboid family UbiA PF01040.13 KFH40619.1 - 0.0023 17.2 5.9 0.0023 17.2 4.1 2.1 2 0 0 2 2 2 1 UbiA prenyltransferase family DUF1435 PF07256.7 KFH40619.1 - 0.074 13.0 0.1 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1435) Glyco_hydro_43 PF04616.9 KFH40621.1 - 3.8e-11 42.6 6.5 7e-10 38.4 1.4 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 Polysacc_deac_1 PF01522.16 KFH40622.1 - 1.8e-19 69.6 0.0 2.5e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase OppC_N PF12911.2 KFH40622.1 - 0.059 12.7 0.8 0.1 11.9 0.5 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C LSM PF01423.17 KFH40623.1 - 1.6e-20 72.4 0.1 1.8e-20 72.2 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KFH40623.1 - 0.00011 22.0 0.1 0.00013 21.8 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.2 KFH40623.1 - 0.092 12.5 0.1 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Scd6-like Sm domain SpoA PF01052.15 KFH40623.1 - 0.13 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Surface presentation of antigens (SPOA) SPAN PF02510.9 KFH40623.1 - 0.14 11.1 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Surface presentation of antigens protein Cys_Met_Meta_PP PF01053.15 KFH40627.1 - 4.9e-60 202.8 0.0 1.1e-59 201.6 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KFH40627.1 - 0.07 12.0 0.0 0.097 11.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II SIR2 PF02146.12 KFH40630.1 - 1.2e-23 83.7 0.0 3.5e-23 82.2 0.0 1.7 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 KFH40630.1 - 0.09 12.5 0.2 1.5 8.6 0.1 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Lamp PF01299.12 KFH40630.1 - 8.9 5.3 8.4 0.31 10.1 1.0 2.2 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) Rad60-SLD PF11976.3 KFH40631.1 - 1.1e-13 50.6 1.2 1.9e-13 49.9 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Cellulase-like PF12876.2 KFH40631.1 - 0.0074 16.7 0.2 0.021 15.2 0.0 1.9 2 0 0 2 2 2 1 Sugar-binding cellulase-like ubiquitin PF00240.18 KFH40631.1 - 0.065 12.6 0.0 0.17 11.3 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin family Methyltransf_11 PF08241.7 KFH40632.1 - 4.5e-11 43.0 0.1 6.5e-10 39.3 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH40632.1 - 4.4e-09 36.8 0.1 2.3e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH40632.1 - 1.2e-07 31.6 0.0 3.1e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH40632.1 - 1.9e-06 27.5 0.0 1.2e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH40632.1 - 2.7e-05 24.5 0.0 7.2e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFH40632.1 - 0.00011 22.1 0.1 0.00029 20.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFH40632.1 - 0.00069 18.7 0.0 0.059 12.4 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KFH40632.1 - 0.013 14.9 0.0 0.033 13.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain DREV PF05219.7 KFH40632.1 - 0.017 14.0 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_25 PF13649.1 KFH40632.1 - 0.11 12.9 0.0 0.44 10.9 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.12 KFH40632.1 - 0.15 11.1 0.0 0.43 9.5 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase IU_nuc_hydro PF01156.14 KFH40633.1 - 4.5e-59 200.1 0.2 1e-44 153.0 0.0 2.1 2 0 0 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase DUF768 PF05589.6 KFH40635.1 - 0.047 13.6 0.1 0.08 12.8 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF768) FAD_binding_3 PF01494.14 KFH40637.1 - 3.4e-06 26.3 3.4 6.4e-06 25.4 0.1 2.5 3 0 0 3 3 3 1 FAD binding domain CMD PF02627.15 KFH40638.1 - 0.012 15.4 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family ketoacyl-synt PF00109.21 KFH40639.1 - 1.3e-62 211.5 0.0 2.4e-62 210.7 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KFH40639.1 - 7.2e-59 198.4 0.0 3.1e-58 196.4 0.0 2.2 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 KFH40639.1 - 3.5e-47 161.2 0.0 1.8e-46 158.9 0.0 2.3 2 1 0 2 2 2 1 Acyl transferase domain adh_short PF00106.20 KFH40639.1 - 1.9e-45 154.7 0.1 7.7e-45 152.8 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 KFH40639.1 - 8.7e-40 136.7 0.3 1.8e-39 135.6 0.2 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KFH40639.1 - 4.4e-39 132.9 0.0 1.1e-38 131.7 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KFH40639.1 - 1.4e-15 57.6 0.0 3.3e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH40639.1 - 8.1e-14 51.6 0.0 2.6e-13 49.9 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH40639.1 - 1.2e-10 41.2 0.0 4e-10 39.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH40639.1 - 1.3e-07 32.0 0.0 3.3e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH40639.1 - 6.7e-07 29.8 0.0 2.3e-06 28.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KFH40639.1 - 1.5e-06 28.3 0.0 4.3e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.13 KFH40639.1 - 1.6e-05 24.1 0.0 3.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KFH40639.1 - 8e-05 22.9 0.0 0.00029 21.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain ACP_syn_III PF08545.5 KFH40639.1 - 0.036 13.7 0.2 0.036 13.7 0.1 2.3 3 0 0 3 3 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_24 PF13578.1 KFH40639.1 - 0.043 14.6 0.0 0.45 11.3 0.0 2.8 2 0 0 2 2 2 0 Methyltransferase domain Mga PF05043.8 KFH40639.1 - 0.074 13.3 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Mga helix-turn-helix domain Methyltransf_PK PF05891.7 KFH40639.1 - 0.094 12.0 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase PCMT PF01135.14 KFH40639.1 - 0.11 12.0 0.0 0.44 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Polysacc_synt_2 PF02719.10 KFH40639.1 - 0.8 8.5 0.0 1.5 7.6 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein F-box PF00646.28 KFH40640.1 - 0.025 14.2 0.5 0.036 13.7 0.3 1.2 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.2 KFH40640.1 - 0.23 11.2 0.7 0.38 10.5 0.5 1.3 1 0 0 1 1 1 0 F-box-like GMC_oxred_N PF00732.14 KFH40641.1 - 1.9e-57 194.7 0.1 2.9e-57 194.1 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFH40641.1 - 3.6e-27 95.4 0.1 7.6e-27 94.3 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KFH40641.1 - 8.9e-05 21.5 0.3 0.28 9.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KFH40641.1 - 0.00011 21.2 0.5 0.00018 20.5 0.1 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 KFH40641.1 - 0.0003 19.8 0.0 0.2 10.5 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFH40641.1 - 0.0062 16.5 0.0 0.02 14.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KFH40641.1 - 0.012 14.6 0.1 2.6 7.0 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 KFH40641.1 - 0.062 12.3 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 KFH40641.1 - 0.082 11.5 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HET PF06985.6 KFH40643.1 - 6.3e-22 78.2 0.0 7.8e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) BBS2_N PF14781.1 KFH40644.1 - 0.042 13.4 0.0 0.11 12.1 0.0 1.7 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal p450 PF00067.17 KFH40645.1 - 3.6e-33 114.7 0.9 1.5e-17 63.3 0.0 2.6 1 1 2 3 3 3 2 Cytochrome P450 DUF2561 PF10812.3 KFH40645.1 - 9.7 5.7 6.8 1.9 8.0 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) Virulence_fact PF13769.1 KFH40646.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Virulence factor p450 PF00067.17 KFH40647.1 - 8e-27 93.8 0.0 1.2e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MMS1_N PF10433.4 KFH40647.1 - 0.25 9.4 0.0 0.4 8.7 0.0 1.2 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term GMC_oxred_N PF00732.14 KFH40648.1 - 1.6e-51 175.2 0.0 2.1e-51 174.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFH40648.1 - 6.2e-33 114.1 0.0 9.2e-33 113.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KFH40648.1 - 0.00018 20.5 0.2 0.0003 19.8 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KFH40648.1 - 0.069 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Secretin_N_2 PF07655.8 KFH40649.1 - 2 8.8 13.6 3.2 8.1 9.4 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain p450 PF00067.17 KFH40650.1 - 1.3e-56 192.1 0.0 1.6e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SSFA2_C PF14723.1 KFH40651.1 - 0.03 14.0 0.4 0.062 13.0 0.1 1.6 2 0 0 2 2 2 0 Sperm-specific antigen 2 C-terminus Terpene_synth_C PF03936.11 KFH40651.1 - 0.054 12.7 0.0 10 5.2 0.0 2.6 2 1 1 3 3 3 0 Terpene synthase family, metal binding domain UMP1 PF05348.6 KFH40651.1 - 0.068 13.1 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 Proteasome maturation factor UMP1 HET PF06985.6 KFH40656.1 - 2.1e-19 70.0 0.0 3.4e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ras PF00071.17 KFH40657.1 - 2.5e-39 134.2 0.0 3.2e-25 88.3 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KFH40657.1 - 2.4e-12 47.3 0.0 4.9e-12 46.3 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 KFH40657.1 - 0.0015 18.4 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 KFH40657.1 - 0.0026 17.0 0.0 0.0073 15.5 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFH40657.1 - 0.048 13.0 0.0 0.95 8.8 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PLAC9 PF15205.1 KFH40657.1 - 0.06 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Placenta-specific protein 9 PRK PF00485.13 KFH40657.1 - 0.076 12.5 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.1 KFH40657.1 - 0.13 12.1 0.4 0.43 10.5 0.1 1.9 1 1 1 2 2 2 0 AAA ATPase domain Peptidase_M28 PF04389.12 KFH40658.1 - 1.1e-33 116.5 0.0 1.7e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KFH40658.1 - 2.5e-15 55.9 0.0 5e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 KFH40658.1 - 5.5e-08 32.5 0.0 1.1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Pyridoxal_deC PF00282.14 KFH40659.1 - 8.4e-79 264.6 0.0 1.4e-78 263.9 0.0 1.3 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 KFH40659.1 - 4.7e-06 25.9 0.9 7.5e-06 25.2 0.0 1.8 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KFH40659.1 - 5.3e-05 22.1 0.0 0.00016 20.5 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V TMPIT PF07851.8 KFH40660.1 - 0.023 13.7 0.3 0.031 13.3 0.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein APC_CDC26 PF10471.4 KFH40660.1 - 5.5 7.7 11.8 0.72 10.6 3.0 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 PUF PF00806.14 KFH40661.1 - 2.6e-11 42.3 0.1 1.2 8.7 0.0 6.7 6 1 1 7 7 7 5 Pumilio-family RNA binding repeat AMMECR1 PF01871.12 KFH40662.1 - 2.3e-44 150.5 0.0 3.9e-44 149.7 0.0 1.3 1 0 0 1 1 1 1 AMMECR1 AstE_AspA PF04952.9 KFH40663.1 - 0.15 10.9 1.1 1.1 8.1 0.0 2.1 2 0 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family HNH PF01844.18 KFH40664.1 - 0.00093 19.0 2.1 0.0019 18.0 1.4 1.6 1 0 0 1 1 1 1 HNH endonuclease HNH_2 PF13391.1 KFH40664.1 - 0.23 11.2 1.6 0.62 9.8 0.6 2.0 2 0 0 2 2 2 0 HNH endonuclease Spore_YtfJ PF09579.5 KFH40665.1 - 0.0095 15.7 1.1 0.017 14.9 0.7 1.4 1 0 0 1 1 1 1 Sporulation protein YtfJ (Spore_YtfJ) DUF1517 PF07466.6 KFH40665.1 - 0.11 11.4 0.2 0.17 10.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Glyco_hydro_12 PF01670.11 KFH40667.1 - 1.1e-11 44.7 0.4 2.9e-11 43.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 12 tRNA-synt_2 PF00152.15 KFH40668.1 - 1.3e-66 224.7 0.0 1.3e-52 178.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 KFH40668.1 - 6.4e-06 25.5 0.0 0.0032 16.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 KFH40668.1 - 0.00064 19.5 0.0 0.009 15.8 0.0 2.2 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 KFH40668.1 - 0.012 15.1 0.0 2.5 7.6 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) Actin PF00022.14 KFH40669.1 - 4.7e-144 479.6 0.0 5.4e-144 479.4 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KFH40669.1 - 0.00064 18.4 0.0 0.73 8.3 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein PIG-P PF08510.7 KFH40670.1 - 7.1e-40 135.5 0.0 9.4e-40 135.1 0.0 1.2 1 0 0 1 1 1 1 PIG-P BNIP3 PF06553.7 KFH40670.1 - 0.063 12.6 2.6 0.093 12.1 1.8 1.2 1 0 0 1 1 1 0 BNIP3 DUF4131 PF13567.1 KFH40670.1 - 0.076 12.4 1.7 0.12 11.7 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) SMN PF06003.7 KFH40670.1 - 5.6 5.9 7.0 8.9 5.3 4.8 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DUF3752 PF12572.3 KFH40671.1 - 4.4e-35 121.0 8.4 4.4e-35 121.0 5.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) Raffinose_syn PF05691.7 KFH40672.1 - 2.9e-51 173.9 0.1 2.3e-41 141.2 0.0 3.2 2 1 1 3 3 3 3 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.13 KFH40672.1 - 8.1e-05 21.4 0.2 0.00013 20.8 0.1 1.2 1 0 0 1 1 1 1 Melibiase ocr PF08684.5 KFH40672.1 - 0.00017 21.5 0.1 0.00041 20.3 0.0 1.6 1 0 0 1 1 1 1 DNA mimic ocr zf-RING_2 PF13639.1 KFH40673.1 - 1.1e-13 50.7 6.4 1.7e-13 50.1 4.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KFH40673.1 - 4.8e-08 32.5 3.2 8e-08 31.8 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFH40673.1 - 4.3e-07 29.9 4.6 8.7e-07 28.9 3.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KFH40673.1 - 6.4e-06 25.8 3.7 1e-05 25.1 2.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFH40673.1 - 2.1e-05 24.4 4.9 3.5e-05 23.7 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFH40673.1 - 4.5e-05 23.0 2.1 6.9e-05 22.4 1.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFH40673.1 - 0.0016 18.2 4.3 0.0039 16.9 3.0 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KFH40673.1 - 0.019 14.5 6.2 0.032 13.8 4.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 KFH40673.1 - 0.11 12.2 5.5 0.19 11.4 3.8 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.1 KFH40673.1 - 0.21 11.5 4.3 0.41 10.5 3.0 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 KFH40673.1 - 0.39 10.6 2.6 1.2 9.1 1.8 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 KFH40673.1 - 0.65 10.0 5.2 1.2 9.1 3.6 1.5 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.1 KFH40673.1 - 1.7 8.4 8.2 5.7 6.7 4.9 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Pyr_redox_2 PF07992.9 KFH40674.1 - 2.2e-28 99.5 0.4 3e-28 99.1 0.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFH40674.1 - 3.9e-18 65.6 1.1 1.3e-15 57.5 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFH40674.1 - 3.5e-10 40.2 0.8 7.3e-06 26.1 0.0 3.1 1 1 2 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KFH40674.1 - 6.5e-07 28.5 5.6 0.031 13.1 0.0 4.0 3 1 1 4 4 4 2 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KFH40674.1 - 9.8e-06 25.7 0.0 0.0036 17.5 0.0 2.6 2 2 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 KFH40674.1 - 2.4e-05 24.2 0.1 0.017 15.0 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KFH40674.1 - 0.00025 20.2 0.5 0.03 13.3 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KFH40674.1 - 0.00025 20.1 0.4 0.0011 18.1 0.0 2.2 2 1 1 3 3 3 1 Thi4 family K_oxygenase PF13434.1 KFH40674.1 - 0.00051 19.0 1.1 0.23 10.3 0.0 3.3 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 KFH40674.1 - 0.0013 18.8 0.4 1.1 9.3 0.0 2.7 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 KFH40674.1 - 0.012 14.6 0.8 3.2 6.7 0.0 3.0 2 1 1 3 3 3 0 FAD binding domain NAD_binding_9 PF13454.1 KFH40674.1 - 0.014 15.1 1.1 1.7 8.3 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.17 KFH40674.1 - 0.019 13.8 6.5 0.61 8.8 0.1 4.0 3 2 0 4 4 4 0 Glucose inhibited division protein A HI0933_like PF03486.9 KFH40674.1 - 0.036 12.5 0.1 1.4 7.2 0.0 2.7 2 1 0 3 3 3 0 HI0933-like protein FAD_binding_2 PF00890.19 KFH40674.1 - 0.057 12.2 4.8 1.2 7.9 3.0 3.0 1 1 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 KFH40674.1 - 0.066 11.8 0.1 0.35 9.4 0.0 2.1 3 0 0 3 3 3 0 Tryptophan halogenase UDG PF03167.14 KFH40675.1 - 7.3e-22 77.4 0.2 5.1e-21 74.7 0.0 2.0 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily DEAD PF00270.24 KFH40676.1 - 7.9e-27 93.8 0.6 3.7e-25 88.3 0.1 2.8 1 1 1 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFH40676.1 - 4.8e-22 77.5 0.1 1.5e-21 75.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFH40676.1 - 0.00036 20.4 2.8 0.00051 19.9 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KFH40676.1 - 0.0022 16.8 0.0 0.0032 16.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Vps8 PF12816.2 KFH40677.1 - 4.1e-71 238.2 0.0 7.4e-71 237.4 0.0 1.4 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 zf-RING_2 PF13639.1 KFH40677.1 - 4.1e-05 23.3 0.1 0.00013 21.7 0.1 1.8 1 0 0 1 1 1 1 Ring finger domain Clathrin PF00637.15 KFH40677.1 - 4.7e-05 23.0 0.0 0.012 15.1 0.0 3.6 5 0 0 5 5 5 1 Region in Clathrin and VPS zf-C3HC4_2 PF13923.1 KFH40677.1 - 0.014 15.3 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFH40677.1 - 0.019 14.7 0.0 0.043 13.5 0.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.2 KFH40677.1 - 0.049 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KFH40677.1 - 0.081 12.6 0.1 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 RING-type zinc-finger PHD PF00628.24 KFH40677.1 - 0.18 11.5 0.3 0.55 9.9 0.2 1.8 1 0 0 1 1 1 0 PHD-finger K_channel_TID PF07941.6 KFH40677.1 - 2.7 8.2 14.9 0.045 13.9 5.0 2.1 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Vps53_N PF04100.7 KFH40678.1 - 1.3e-102 343.4 0.2 2e-102 342.8 0.1 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 KFH40678.1 - 1.8e-07 30.3 6.2 3.2e-07 29.5 4.3 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Zw10 PF06248.8 KFH40678.1 - 0.0024 16.1 4.1 0.0051 15.0 2.8 1.5 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Spc7 PF08317.6 KFH40678.1 - 0.0053 15.4 3.7 0.0091 14.6 2.5 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein COG5 PF10392.4 KFH40678.1 - 0.38 10.6 7.4 0.87 9.5 1.6 3.6 3 1 1 4 4 4 0 Golgi transport complex subunit 5 Baculo_PEP_C PF04513.7 KFH40678.1 - 1.4 8.7 4.9 3 7.6 3.1 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.6 KFH40678.1 - 2.2 8.1 5.5 2.8 7.8 2.4 2.3 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2834 PF11196.3 KFH40679.1 - 0.0027 17.8 19.4 0.028 14.5 0.6 4.1 3 1 0 3 3 3 2 Protein of unknown function (DUF2834) DUF2569 PF10754.4 KFH40679.1 - 0.056 13.6 1.9 0.75 9.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) WD40 PF00400.27 KFH40680.1 - 4.5e-27 92.9 2.5 9.9e-11 41.0 0.1 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 KFH40680.1 - 0.0012 18.6 0.1 0.4 10.3 0.0 3.1 1 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 KFH40680.1 - 0.0026 16.6 0.1 0.098 11.4 0.1 2.1 1 1 1 2 2 2 2 Coatomer WD associated region Nup160 PF11715.3 KFH40680.1 - 0.0084 14.2 0.0 0.012 13.7 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KFH40680.1 - 0.093 12.1 0.2 1.4 8.3 0.0 2.1 1 1 1 2 2 2 0 PQQ-like domain RRM_1 PF00076.17 KFH40681.1 - 4.2e-17 61.5 0.0 6.8e-17 60.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH40681.1 - 2.4e-15 56.2 0.0 4.7e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH40681.1 - 2.1e-05 24.2 0.0 3.9e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NPV_P10 PF05531.7 KFH40681.1 - 0.0018 18.5 0.8 0.0032 17.6 0.6 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.14 KFH40681.1 - 0.013 13.3 1.3 0.016 13.1 0.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CASP_C PF08172.7 KFH40681.1 - 0.031 13.3 0.1 0.047 12.7 0.1 1.2 1 0 0 1 1 1 0 CASP C terminal Filament PF00038.16 KFH40681.1 - 0.1 12.0 6.7 0.13 11.6 4.6 1.1 1 0 0 1 1 1 0 Intermediate filament protein HAP1_N PF04849.8 KFH40681.1 - 0.13 11.2 9.4 0.18 10.7 6.5 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF972 PF06156.8 KFH40681.1 - 0.14 12.5 1.4 0.19 12.0 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) CPSF100_C PF13299.1 KFH40681.1 - 0.14 12.2 2.7 0.22 11.7 1.9 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal MMPL PF03176.10 KFH40681.1 - 0.16 10.6 0.6 0.18 10.5 0.4 1.1 1 0 0 1 1 1 0 MMPL family IncA PF04156.9 KFH40681.1 - 0.17 11.4 4.3 0.21 11.1 3.0 1.1 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 KFH40681.1 - 0.18 11.2 2.7 0.3 10.6 1.9 1.3 1 0 0 1 1 1 0 Septum formation initiator APG6 PF04111.7 KFH40681.1 - 0.28 10.1 3.7 0.33 9.9 2.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF904 PF06005.7 KFH40681.1 - 0.4 10.9 6.5 0.67 10.2 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) EMP24_GP25L PF01105.19 KFH40681.1 - 0.44 10.2 3.2 0.61 9.7 2.2 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Packaging_FI PF14000.1 KFH40681.1 - 0.48 10.6 6.5 0.12 12.6 2.2 1.7 1 1 1 2 2 2 0 DNA packaging protein FI Oxidored_q6 PF01058.17 KFH40682.1 - 2.2e-22 79.0 0.0 3e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit RabGAP-TBC PF00566.13 KFH40683.1 - 2.9e-49 167.4 0.0 4.3e-49 166.8 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RRM_1 PF00076.17 KFH40684.1 - 5.7e-23 80.3 0.2 8.5e-18 63.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH40684.1 - 1.3e-16 60.2 9.7 5e-15 55.2 0.0 3.4 4 0 0 4 4 4 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH40684.1 - 9.2e-06 25.4 0.8 0.00016 21.4 0.0 2.7 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFH40684.1 - 0.087 12.6 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF1631 PF07793.6 KFH40684.1 - 3.8 5.5 8.5 4.9 5.1 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) p450 PF00067.17 KFH40685.1 - 3.1e-56 190.8 0.0 4.7e-43 147.3 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 SNF2_N PF00176.18 KFH40686.1 - 2.9e-81 272.5 0.2 4.7e-81 271.8 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 KFH40686.1 - 2.9e-43 146.3 2.6 2.9e-43 146.3 1.8 2.6 3 0 0 3 3 3 1 SLIDE HAND PF09110.6 KFH40686.1 - 5.4e-32 110.5 4.8 5.4e-32 110.5 3.3 3.3 4 0 0 4 4 4 1 HAND Helicase_C PF00271.26 KFH40686.1 - 1.8e-15 56.5 0.2 9.4e-15 54.2 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KFH40686.1 - 8.9e-10 37.8 0.0 2.1e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 KFH40686.1 - 3.3e-06 27.0 0.0 4.2e-05 23.4 0.0 3.0 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KFH40686.1 - 2.6e-05 23.7 0.0 6.7e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 KFH40686.1 - 0.021 14.2 0.0 0.049 13.0 0.0 1.6 1 0 0 1 1 1 0 DEAD_2 Ion_trans PF00520.26 KFH40687.1 - 2.4e-05 23.6 1.4 2.4e-05 23.6 1.0 1.6 2 0 0 2 2 2 1 Ion transport protein PKD_channel PF08016.7 KFH40687.1 - 0.0061 15.0 0.4 0.009 14.4 0.3 1.3 1 0 0 1 1 1 1 Polycystin cation channel DivIC PF04977.10 KFH40687.1 - 0.0085 15.5 1.0 0.017 14.6 0.7 1.4 1 0 0 1 1 1 1 Septum formation initiator Mto2_bdg PF12808.2 KFH40687.1 - 0.012 15.6 0.4 0.023 14.8 0.3 1.4 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Nnf1 PF03980.9 KFH40687.1 - 0.024 14.6 0.3 0.037 14.0 0.2 1.3 1 0 0 1 1 1 0 Nnf1 bZIP_2 PF07716.10 KFH40687.1 - 0.026 14.3 1.2 0.044 13.5 0.8 1.3 1 0 0 1 1 1 0 Basic region leucine zipper DUF2681 PF10883.3 KFH40687.1 - 0.042 14.0 0.1 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF4140 PF13600.1 KFH40687.1 - 0.12 12.8 0.1 0.16 12.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) HALZ PF02183.13 KFH40687.1 - 0.18 11.5 0.7 0.37 10.5 0.3 1.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper IncA PF04156.9 KFH40687.1 - 0.32 10.5 7.0 0.029 13.9 1.7 1.6 2 1 0 2 2 2 0 IncA protein HECT PF00632.20 KFH40688.1 - 7.8e-93 311.0 0.0 1.1e-92 310.5 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KFH40688.1 - 2.5e-33 113.5 17.4 2e-11 43.4 1.4 3.7 3 0 0 3 3 3 3 WW domain C2 PF00168.25 KFH40688.1 - 2.7e-16 59.1 0.1 6.1e-16 58.0 0.1 1.6 1 0 0 1 1 1 1 C2 domain Glyco_transf_90 PF05686.7 KFH40689.1 - 8e-13 47.8 1.6 2e-11 43.2 0.0 2.9 2 2 0 2 2 2 2 Glycosyl transferase family 90 DUF4588 PF15251.1 KFH40690.1 - 8.8e-06 25.8 3.6 2.2e-05 24.5 2.5 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) PPP4R2 PF09184.6 KFH40691.1 - 3.4 7.1 6.6 3.8 6.9 4.6 1.2 1 0 0 1 1 1 0 PPP4R2 CAP_N PF01213.14 KFH40691.1 - 5.5 6.1 5.5 0.39 9.9 0.4 1.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal CD52 PF15116.1 KFH40692.1 - 0.22 11.3 6.3 0.16 11.8 1.2 3.3 3 0 0 3 3 3 0 CAMPATH-1 antigen RNase_PH PF01138.16 KFH40694.1 - 2.7e-14 53.6 0.0 4.7e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KFH40694.1 - 0.0044 16.9 0.0 0.009 15.9 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 NUDIX PF00293.23 KFH40695.1 - 1.5e-17 63.5 0.6 1.8e-17 63.2 0.4 1.1 1 0 0 1 1 1 1 NUDIX domain AAA PF00004.24 KFH40696.1 - 9.6e-63 210.2 0.0 4.8e-46 156.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFH40696.1 - 9.3e-11 42.0 4.0 0.00022 21.2 0.0 4.1 3 2 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 KFH40696.1 - 3.7e-10 40.0 0.0 0.0025 17.9 0.0 5.0 3 2 1 4 4 4 2 AAA domain AAA_5 PF07728.9 KFH40696.1 - 8.2e-10 38.5 0.4 0.002 17.8 0.0 4.4 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KFH40696.1 - 1.8e-09 38.4 0.1 0.0012 19.6 0.0 3.6 3 1 0 4 4 3 2 AAA domain RuvB_N PF05496.7 KFH40696.1 - 3.9e-07 29.3 0.0 0.00094 18.2 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KFH40696.1 - 6.6e-07 29.3 0.0 0.0014 18.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.1 KFH40696.1 - 9e-07 28.8 0.0 0.00051 19.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KFH40696.1 - 9.3e-07 29.2 0.0 0.014 15.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 KFH40696.1 - 1.2e-06 28.5 0.0 0.00061 19.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 KFH40696.1 - 1.9e-05 24.3 0.0 0.0057 16.3 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 KFH40696.1 - 3.1e-05 23.1 0.0 0.00047 19.3 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.17 KFH40696.1 - 8.3e-05 22.7 0.0 0.061 13.5 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Sigma54_activ_2 PF14532.1 KFH40696.1 - 0.00013 22.0 0.0 0.25 11.3 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.12 KFH40696.1 - 0.00013 21.4 0.0 0.014 14.7 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.8 KFH40696.1 - 0.00016 20.5 0.0 0.23 10.1 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus Cytidylate_kin2 PF13189.1 KFH40696.1 - 0.00036 20.5 0.1 0.043 13.7 0.0 2.8 3 0 0 3 3 2 1 Cytidylate kinase-like family SKI PF01202.17 KFH40696.1 - 0.00044 20.1 0.1 3 7.6 0.0 4.0 4 0 0 4 4 4 1 Shikimate kinase NACHT PF05729.7 KFH40696.1 - 0.00051 19.7 0.1 0.71 9.5 0.0 3.2 3 0 0 3 3 3 1 NACHT domain AAA_28 PF13521.1 KFH40696.1 - 0.00055 19.9 0.0 0.31 10.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 KFH40696.1 - 0.00061 18.7 0.0 0.76 8.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 KFH40696.1 - 0.00066 18.8 0.1 0.2 10.7 0.0 2.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KFH40696.1 - 0.0015 17.9 0.1 3.8 6.8 0.1 3.6 2 1 0 3 3 3 1 AAA domain Thymidylate_kin PF02223.12 KFH40696.1 - 0.0039 16.5 0.0 0.056 12.8 0.0 2.5 2 0 0 2 2 2 1 Thymidylate kinase ABC_tran PF00005.22 KFH40696.1 - 0.0052 17.0 0.0 0.44 10.8 0.0 2.9 3 0 0 3 3 2 1 ABC transporter ResIII PF04851.10 KFH40696.1 - 0.0072 16.1 0.0 0.026 14.3 0.0 1.9 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit AAA_3 PF07726.6 KFH40696.1 - 0.011 15.3 0.0 4.1 7.0 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 KFH40696.1 - 0.018 14.7 0.0 5 6.8 0.0 2.7 2 1 0 2 2 2 0 NTPase ATP-synt_ab PF00006.20 KFH40696.1 - 0.02 14.3 0.0 0.26 10.7 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activat PF00158.21 KFH40696.1 - 0.021 14.3 0.0 0.55 9.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain UPF0079 PF02367.12 KFH40696.1 - 0.04 13.5 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 KFH40696.1 - 0.051 13.2 0.0 10 5.7 0.0 2.8 2 1 1 3 3 3 0 Archaeal ATPase Viral_helicase1 PF01443.13 KFH40696.1 - 0.073 12.5 0.0 0.5 9.8 0.0 2.3 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Rad17 PF03215.10 KFH40696.1 - 0.083 11.5 0.0 2.5 6.6 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein DUF258 PF03193.11 KFH40696.1 - 0.093 11.9 0.0 0.69 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 NB-ARC PF00931.17 KFH40696.1 - 0.13 11.0 0.0 0.78 8.5 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Cytochrom_C PF00034.16 KFH40697.1 - 1.1e-11 45.4 0.1 1.6e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 KFH40697.1 - 9.3e-09 35.3 3.1 5e-08 32.9 2.1 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 KFH40697.1 - 0.0027 17.1 1.9 0.021 14.3 1.2 2.3 1 1 0 1 1 1 1 Cytochrome c-550 domain CCP_MauG PF03150.9 KFH40697.1 - 0.072 13.3 0.1 0.11 12.7 0.1 1.4 1 1 0 1 1 1 0 Di-haem cytochrome c peroxidase Fructosamin_kin PF03881.9 KFH40698.1 - 1.2e-76 257.5 0.0 1.3e-76 257.2 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KFH40698.1 - 1.2e-06 28.4 0.0 1.7e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KFH40698.1 - 0.11 11.0 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Pkinase PF00069.20 KFH40699.1 - 1.2e-22 80.3 0.0 5.2e-22 78.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH40699.1 - 6.1e-09 35.3 0.0 3e-05 23.2 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Fe-S_biosyn PF01521.15 KFH40700.1 - 5.3e-19 68.2 0.0 7e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF605 PF04652.11 KFH40700.1 - 0.33 10.2 26.6 0.41 10.0 18.5 1.1 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 KFH40700.1 - 0.81 9.5 11.7 0.95 9.2 8.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CENP-U PF13097.1 KFH40700.1 - 1.2 8.9 11.0 1.7 8.5 7.6 1.2 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit RR_TM4-6 PF06459.7 KFH40700.1 - 3 7.6 8.2 3.7 7.3 5.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PAT1 PF09770.4 KFH40700.1 - 3.3 5.8 22.9 3.8 5.6 15.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AvrE PF11725.3 KFH40700.1 - 3.9 4.3 9.1 4.6 4.1 6.3 1.0 1 0 0 1 1 1 0 Pathogenicity factor ATE_C PF04377.10 KFH40703.1 - 3.3e-42 143.5 0.3 5.7e-42 142.7 0.2 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 KFH40703.1 - 7.3e-15 54.5 0.8 7.3e-15 54.5 0.6 1.7 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.1 KFH40703.1 - 0.19 11.7 1.5 0.37 10.7 0.1 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Snf7 PF03357.16 KFH40704.1 - 2.1e-36 124.9 11.9 2.6e-36 124.5 8.3 1.1 1 0 0 1 1 1 1 Snf7 DUF2520 PF10728.4 KFH40704.1 - 0.0022 17.4 0.1 0.005 16.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2520) RelA_SpoT PF04607.12 KFH40704.1 - 0.075 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Region found in RelA / SpoT proteins DELLA PF12041.3 KFH40704.1 - 0.12 12.0 3.6 1.6 8.4 0.1 3.0 2 1 1 3 3 3 0 Transcriptional regulator DELLA protein N terminal DUF1843 PF08898.5 KFH40704.1 - 7.1 6.7 10.0 16 5.6 0.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) Dynamin_N PF00350.18 KFH40705.1 - 7.1e-29 100.7 0.0 1.3e-28 99.8 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KFH40705.1 - 8.9e-16 57.5 0.2 3e-14 52.4 0.0 2.5 3 0 0 3 3 3 1 Dynamin central region GED PF02212.13 KFH40705.1 - 0.00026 20.8 0.6 0.0058 16.5 0.1 2.6 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KFH40705.1 - 0.00094 19.1 0.0 0.0031 17.4 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFH40705.1 - 0.0014 19.1 0.0 0.004 17.6 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_21 PF13304.1 KFH40705.1 - 0.0034 17.3 0.0 0.0065 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KFH40705.1 - 0.052 13.0 0.2 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KFH40705.1 - 0.082 13.2 0.0 0.38 11.0 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_23 PF13476.1 KFH40705.1 - 0.11 12.8 0.3 0.42 10.9 0.0 1.8 2 1 0 2 2 2 0 AAA domain DNA_binding_1 PF01035.15 KFH40706.1 - 2.7e-24 84.7 0.0 3.8e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Dicty_REP PF05086.7 KFH40706.1 - 4.7 4.8 4.6 5.7 4.5 3.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Glyco_hydro_61 PF03443.9 KFH40707.1 - 1.3e-30 106.8 0.2 1.6e-30 106.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4469 PF14734.1 KFH40707.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4469) with IG-like fold DUF2235 PF09994.4 KFH40708.1 - 3.4e-51 174.2 0.0 7.7e-51 173.0 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Peptidase_M20 PF01546.23 KFH40709.1 - 0.00042 19.8 0.7 0.001 18.6 0.2 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 KFH40710.1 - 2.6e-07 30.2 3.8 0.009 15.8 0.2 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat CDC45 PF02724.9 KFH40710.1 - 0.0058 14.7 8.9 0.008 14.2 6.2 1.1 1 0 0 1 1 1 1 CDC45-like protein Nup160 PF11715.3 KFH40710.1 - 0.031 12.4 0.0 0.054 11.6 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 TFIIF_alpha PF05793.7 KFH40710.1 - 0.22 9.8 14.8 0.31 9.3 10.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 KFH40710.1 - 0.62 7.9 13.3 0.82 7.5 9.2 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.7 KFH40710.1 - 2.9 7.5 13.3 4.4 6.9 9.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein YL1 PF05764.8 KFH40710.1 - 4.5 6.7 11.4 6.9 6.2 7.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein mRNA_triPase PF02940.10 KFH40711.1 - 1.1e-52 178.9 0.1 2.9e-52 177.5 0.1 1.8 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Glyco_hydro_43 PF04616.9 KFH40712.1 - 2.4e-41 141.6 6.6 3.5e-41 141.1 4.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Fe-ADH PF00465.14 KFH40713.1 - 9.4e-15 54.1 0.0 1.4e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KFH40713.1 - 2e-05 24.0 0.0 2e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase Xan_ur_permease PF00860.15 KFH40714.1 - 1.3e-65 221.4 26.8 7.5e-64 215.6 18.6 2.1 1 1 0 1 1 1 1 Permease family tRNA-synt_1d PF00750.14 KFH40715.1 - 4.5e-47 160.5 0.0 7.9e-47 159.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 KFH40715.1 - 6.7e-13 48.6 0.0 1.6e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain PS_pyruv_trans PF04230.8 KFH40716.1 - 9.8e-19 68.1 0.0 3.2e-18 66.4 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide pyruvyl transferase TPT PF03151.11 KFH40717.1 - 2.7e-15 56.3 15.9 1.9e-14 53.5 3.6 2.2 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 KFH40717.1 - 1.4e-05 25.0 22.9 0.0071 16.3 3.1 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 KFH40717.1 - 1.8e-05 23.7 12.0 6.8e-05 21.9 7.8 1.8 1 1 0 1 1 1 1 UAA transporter family ATP_bind_1 PF03029.12 KFH40718.1 - 5.1e-73 245.5 0.0 7e-73 245.0 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 KFH40718.1 - 0.0019 17.6 0.0 0.0034 16.8 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.17 KFH40718.1 - 0.0036 16.7 0.0 1.8 7.9 0.0 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain GTP_EFTU PF00009.22 KFH40718.1 - 0.0086 15.5 0.0 0.13 11.6 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 KFH40718.1 - 0.0099 14.6 0.0 1.7 7.3 0.0 2.6 3 0 0 3 3 3 1 ArgK protein AAA_10 PF12846.2 KFH40718.1 - 0.013 14.9 0.1 0.12 11.7 0.1 2.1 1 1 0 1 1 1 0 AAA-like domain PRK PF00485.13 KFH40718.1 - 0.021 14.3 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 KFH40718.1 - 0.053 14.3 0.2 0.42 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.13 KFH40718.1 - 0.057 12.7 0.0 0.14 11.4 0.0 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B KAP_NTPase PF07693.9 KFH40718.1 - 0.083 11.8 0.0 0.16 10.9 0.0 1.5 2 0 0 2 2 2 0 KAP family P-loop domain AAA_19 PF13245.1 KFH40718.1 - 0.095 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Miro PF08477.8 KFH40718.1 - 0.11 13.0 0.0 1.5 9.3 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein AAA_22 PF13401.1 KFH40718.1 - 0.13 12.4 0.0 0.44 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain Cwf_Cwc_15 PF04889.7 KFH40719.1 - 0.0019 17.9 4.8 0.0022 17.7 3.3 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Dicty_REP PF05086.7 KFH40719.1 - 0.63 7.7 9.5 0.67 7.6 6.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CDK5_activator PF03261.10 KFH40719.1 - 2.9 7.1 9.8 3.3 6.9 6.8 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein TPR_11 PF13414.1 KFH40720.1 - 4.6e-05 22.9 14.1 0.13 11.9 0.6 6.4 6 1 1 7 7 7 3 TPR repeat TPR_17 PF13431.1 KFH40720.1 - 0.00028 20.8 0.1 9 6.7 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFH40720.1 - 0.013 15.8 3.6 11 6.4 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFH40720.1 - 4.9 8.0 17.3 3.9 8.3 0.2 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Aldo_ket_red PF00248.16 KFH40721.1 - 8.3e-52 175.7 0.0 9.9e-52 175.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family UDPGT PF00201.13 KFH40721.1 - 0.066 11.7 0.0 0.089 11.3 0.0 1.2 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Leu_Phe_trans PF03588.9 KFH40721.1 - 0.16 11.0 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Leucyl/phenylalanyl-tRNA protein transferase Apt1 PF10351.4 KFH40722.1 - 0.2 10.4 1.6 0.29 9.9 1.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain NOA36 PF06524.7 KFH40722.1 - 1 8.5 20.9 0.17 11.0 6.4 2.2 2 0 0 2 2 2 0 NOA36 protein PRP21_like_P PF12230.3 KFH40722.1 - 2.1 7.7 15.9 0.82 9.1 1.0 2.3 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein Nop14 PF04147.7 KFH40722.1 - 8.8 4.1 30.9 0.037 11.9 7.4 2.1 2 0 0 2 2 2 0 Nop14-like family ChAPs PF09295.5 KFH40724.1 - 2.1e-155 517.3 0.0 2.9e-155 516.9 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 KFH40724.1 - 6.8e-07 28.8 1.0 0.0054 16.3 0.0 3.1 3 0 0 3 3 3 2 TPR repeat TPR_14 PF13428.1 KFH40724.1 - 7.5e-06 26.1 0.9 1.1 10.0 0.0 4.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFH40724.1 - 2.1e-05 23.9 0.1 0.023 14.4 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFH40724.1 - 2.5e-05 24.0 0.6 0.012 15.4 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFH40724.1 - 2.9e-05 23.5 0.2 0.33 10.8 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFH40724.1 - 0.00017 21.2 0.2 0.064 13.1 0.2 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat Apc3 PF12895.2 KFH40724.1 - 0.0017 18.4 0.6 2.6 8.2 0.0 3.7 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 KFH40724.1 - 0.0022 17.5 0.2 0.78 9.4 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFH40724.1 - 0.014 15.7 0.1 21 5.5 0.1 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFH40724.1 - 0.015 15.7 0.7 25 5.6 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 KFH40724.1 - 0.021 14.7 0.0 6.9 6.6 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.1 KFH40724.1 - 0.034 13.1 6.4 0.058 12.4 0.9 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2007 PF09413.5 KFH40724.1 - 0.05 13.4 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2007) HIT PF01230.18 KFH40725.1 - 4.5e-19 68.8 0.0 7.2e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KFH40725.1 - 4.1e-08 33.4 0.0 1.2e-07 31.9 0.0 1.6 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding Strep_his_triad PF04270.8 KFH40725.1 - 0.025 14.2 0.1 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Streptococcal histidine triad protein CwfJ_C_1 PF04677.10 KFH40725.1 - 0.035 13.7 0.0 0.062 12.9 0.0 1.4 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 DUF3589 PF12141.3 KFH40726.1 - 0.23 9.6 0.1 0.37 8.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3589) DNA_RNApol_7kD PF03604.8 KFH40727.1 - 5.2e-09 35.4 0.6 6.8e-09 35.0 0.4 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit Auto_anti-p27 PF06677.7 KFH40727.1 - 0.0068 16.1 1.1 0.014 15.1 0.8 1.5 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn_Tnp_IS1595 PF12760.2 KFH40727.1 - 0.02 14.7 2.0 0.13 12.0 0.1 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain HypA PF01155.14 KFH40727.1 - 0.02 14.5 0.2 0.024 14.3 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 KFH40727.1 - 0.026 14.4 1.8 0.096 12.6 1.3 1.8 1 1 0 1 1 1 0 Zinc ribbon domain zf-RING_3 PF14369.1 KFH40727.1 - 0.026 14.5 0.7 0.048 13.6 0.5 1.5 1 1 0 1 1 1 0 zinc-finger A2L_zn_ribbon PF08792.5 KFH40727.1 - 0.028 13.8 0.3 0.044 13.2 0.2 1.3 1 0 0 1 1 1 0 A2L zinc ribbon domain DZR PF12773.2 KFH40727.1 - 0.035 13.9 0.2 0.049 13.4 0.1 1.3 1 0 0 1 1 1 0 Double zinc ribbon DnaJ_CXXCXGXG PF00684.14 KFH40727.1 - 0.037 14.0 1.0 0.062 13.3 0.5 1.5 1 1 0 1 1 1 0 DnaJ central domain PhnA_Zn_Ribbon PF08274.7 KFH40727.1 - 0.037 13.8 0.6 0.057 13.2 0.2 1.5 2 0 0 2 2 1 0 PhnA Zinc-Ribbon Prok-RING_1 PF14446.1 KFH40727.1 - 0.05 13.3 0.5 0.069 12.9 0.3 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DUF2197 PF09963.4 KFH40727.1 - 0.06 13.3 0.5 0.9 9.5 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-C2HC5 PF06221.8 KFH40727.1 - 0.083 12.6 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type NinF PF05810.7 KFH40727.1 - 0.13 12.0 0.1 0.17 11.6 0.1 1.1 1 0 0 1 1 1 0 NinF protein DUF329 PF03884.9 KFH40727.1 - 0.16 11.5 0.3 2.5 7.7 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF329) Lar_restr_allev PF14354.1 KFH40727.1 - 0.18 12.1 2.4 3 8.2 0.1 2.1 1 1 1 2 2 2 0 Restriction alleviation protein Lar TF_Zn_Ribbon PF08271.7 KFH40727.1 - 0.31 10.3 1.4 1.2 8.4 1.0 1.9 1 1 0 1 1 1 0 TFIIB zinc-binding Zn_ribbon_recom PF13408.1 KFH40727.1 - 1.5 9.1 7.1 11 6.3 0.2 2.6 1 1 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-NADH-PPase PF09297.6 KFH40727.1 - 2.9 7.4 5.9 2 7.9 1.0 2.4 2 1 1 3 3 3 0 NADH pyrophosphatase zinc ribbon domain A_deaminase PF00962.17 KFH40728.1 - 3.1e-109 364.8 0.2 4e-109 364.5 0.1 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Prefoldin_2 PF01920.15 KFH40729.1 - 3.5e-12 46.0 2.1 6.5e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 Prefoldin subunit TMF_TATA_bd PF12325.3 KFH40729.1 - 0.16 11.6 7.5 0.34 10.6 0.4 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Mito_carr PF00153.22 KFH40730.1 - 7.2e-54 179.4 0.7 2e-17 62.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SH3_1 PF00018.23 KFH40731.1 - 9.8e-39 130.5 6.8 5e-14 51.4 0.1 4.4 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.7 KFH40731.1 - 1.8e-35 120.4 0.1 3e-35 119.6 0.1 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.1 KFH40731.1 - 3.9e-33 112.7 8.7 2.6e-12 46.1 0.2 4.0 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 KFH40731.1 - 8.2e-24 82.8 0.3 1.8e-07 30.4 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain SH3_3 PF08239.6 KFH40731.1 - 0.00016 21.8 8.1 0.0079 16.3 0.4 3.7 4 0 0 4 4 4 2 Bacterial SH3 domain DUF1720 PF08226.6 KFH40731.1 - 0.012 15.6 36.5 0.012 15.6 25.3 5.9 2 1 2 4 4 4 0 Domain of unknown function (DUF1720) UAA PF08449.6 KFH40732.1 - 3.6e-85 285.5 4.7 4.3e-85 285.2 3.2 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 KFH40732.1 - 7.9e-05 21.8 0.1 0.00023 20.3 0.0 1.8 1 0 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.1 KFH40732.1 - 0.024 14.8 14.6 0.028 14.5 0.6 3.3 3 1 0 3 3 3 0 Multidrug resistance efflux transporter DUF3154 PF11351.3 KFH40732.1 - 0.13 11.9 0.3 0.98 9.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3154) DUF4231 PF14015.1 KFH40732.1 - 0.54 10.2 0.0 0.54 10.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) TPT PF03151.11 KFH40732.1 - 2.6 7.6 12.6 0.19 11.3 4.1 2.5 3 1 0 3 3 3 0 Triose-phosphate Transporter family DUF4131 PF13567.1 KFH40732.1 - 6.7 6.0 11.6 6.7 6.0 0.4 3.4 2 1 1 4 4 4 0 Domain of unknown function (DUF4131) EamA PF00892.15 KFH40732.1 - 7 6.7 20.6 0.26 11.3 2.9 3.5 3 1 1 4 4 4 0 EamA-like transporter family TRAM_LAG1_CLN8 PF03798.11 KFH40733.1 - 1.2e-44 152.2 13.2 1.2e-44 152.2 9.1 1.5 2 0 0 2 2 2 1 TLC domain DUF4234 PF14018.1 KFH40733.1 - 0.024 14.3 0.1 0.08 12.6 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) YqhG PF11079.3 KFH40734.1 - 0.081 11.7 8.4 0.15 10.8 5.8 1.4 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function DUF3584 PF12128.3 KFH40734.1 - 5.8 4.1 35.0 7.4 3.7 24.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Dor1 PF04124.7 KFH40735.1 - 5.5e-51 173.0 0.3 5.6e-42 143.4 0.4 2.2 2 0 0 2 2 2 2 Dor1-like family COG5 PF10392.4 KFH40735.1 - 0.049 13.5 2.8 0.16 11.9 1.5 2.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Voltage_CLC PF00654.15 KFH40736.1 - 9.7e-64 215.6 29.3 5.5e-46 157.2 14.0 2.9 2 1 1 3 3 3 2 Voltage gated chloride channel CBS PF00571.23 KFH40736.1 - 8.1e-07 28.7 0.1 0.0082 15.9 0.0 2.4 2 0 0 2 2 2 2 CBS domain Arginase PF00491.16 KFH40737.1 - 1.2e-89 300.2 0.0 1.5e-89 300.0 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 KFH40737.1 - 0.086 13.0 0.5 0.19 11.9 0.2 1.7 1 1 1 2 2 2 0 UPF0489 domain Aconitase PF00330.15 KFH40738.1 - 1.8e-179 597.1 0.0 2.1e-179 596.9 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KFH40738.1 - 7.3e-47 158.7 0.0 1.2e-46 158.0 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain E1_dh PF00676.15 KFH40739.1 - 1.1e-111 372.3 0.2 1.4e-111 372.0 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 KFH40739.1 - 0.00022 20.2 0.0 0.0008 18.4 0.0 1.8 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase AIF-MLS PF14962.1 KFH40739.1 - 0.35 10.5 4.3 3.8 7.1 0.1 2.2 2 0 0 2 2 2 0 Mitochondria Localisation Sequence Phage_lysozyme PF00959.14 KFH40740.1 - 1.2e-14 54.5 0.0 1.5e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Phage lysozyme tRNA-synt_2 PF00152.15 KFH40741.1 - 5e-71 239.1 0.0 9.1e-71 238.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KFH40741.1 - 1.3e-08 34.5 0.0 2.2e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain ATP-synt_D PF01813.12 KFH40742.1 - 0.00055 19.5 1.4 0.011 15.3 0.0 2.1 2 0 0 2 2 2 1 ATP synthase subunit D Daxx PF03344.10 KFH40742.1 - 0.05 12.0 10.8 0.19 10.1 2.4 2.0 2 0 0 2 2 2 0 Daxx Family FadA PF09403.5 KFH40742.1 - 1 9.3 9.5 0.32 11.0 0.3 2.9 3 0 0 3 3 3 0 Adhesion protein FadA CAF1A PF12253.3 KFH40742.1 - 2.9 8.0 8.5 5 7.3 5.9 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A Neurochondrin PF05536.6 KFH40743.1 - 1.8e-95 320.3 1.1 2.4e-95 319.9 0.8 1.1 1 0 0 1 1 1 1 Neurochondrin V-ATPase_H_N PF03224.9 KFH40743.1 - 0.00012 21.2 1.1 0.033 13.3 0.4 2.3 2 0 0 2 2 2 2 V-ATPase subunit H RIX1 PF08167.7 KFH40743.1 - 0.073 12.7 1.3 0.69 9.5 0.7 2.9 1 1 1 2 2 2 0 rRNA processing/ribosome biogenesis DUF2411 PF10304.4 KFH40743.1 - 2.4 7.7 7.7 12 5.5 1.3 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF2411) Pyr_redox_2 PF07992.9 KFH40744.1 - 2.2e-33 115.8 0.2 2.9e-33 115.4 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KFH40744.1 - 5e-20 71.5 0.2 2.8e-19 69.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KFH40744.1 - 5.9e-20 71.4 0.0 2.1e-17 63.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFH40744.1 - 7.5e-09 35.9 0.0 0.00043 20.3 0.0 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFH40744.1 - 0.00032 19.7 0.0 0.0025 16.8 0.0 2.3 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.13 KFH40744.1 - 0.0072 16.0 0.1 0.17 11.5 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KFH40744.1 - 0.028 14.6 0.1 0.38 11.0 0.0 2.6 3 0 0 3 3 3 0 Putative NAD(P)-binding DAO PF01266.19 KFH40744.1 - 0.06 12.2 0.0 0.06 12.2 0.0 2.3 2 1 1 3 3 3 0 FAD dependent oxidoreductase HI0933_like PF03486.9 KFH40744.1 - 0.078 11.4 0.0 0.25 9.7 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein 2-Hacid_dh_C PF02826.14 KFH40744.1 - 0.084 12.0 0.3 0.28 10.3 0.0 2.0 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KFH40744.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF1768 PF08719.6 KFH40745.1 - 6.3e-46 155.9 0.0 7.8e-46 155.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) WD40 PF00400.27 KFH40746.1 - 1.9e-51 170.1 16.2 1.5e-10 40.5 0.1 7.0 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.2 KFH40746.1 - 1.8e-11 43.5 0.5 3.2e-11 42.7 0.4 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 KFH40746.1 - 1.8e-08 33.0 8.4 0.043 11.9 0.1 5.3 1 1 4 5 5 5 4 Nucleoporin Nup120/160 F-box PF00646.28 KFH40746.1 - 2.1e-05 24.0 1.6 4.3e-05 23.0 1.1 1.6 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 KFH40746.1 - 3.4e-05 23.4 3.1 0.36 10.2 0.1 3.9 2 1 1 3 3 3 2 PQQ-like domain PQQ_3 PF13570.1 KFH40746.1 - 0.14 12.4 5.1 65 3.9 0.0 5.5 6 2 1 7 7 7 0 PQQ-like domain DNA_ligase_A_N PF04675.9 KFH40747.1 - 1.8e-54 184.2 0.0 3.3e-54 183.3 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.16 KFH40747.1 - 5.9e-45 153.1 0.3 9.9e-45 152.3 0.2 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.10 KFH40747.1 - 1.9e-28 98.7 0.0 7.1e-28 96.8 0.0 2.1 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 KFH40747.1 - 0.031 13.9 0.1 9.1 6.0 0.0 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain Ras PF00071.17 KFH40748.1 - 2e-52 176.8 0.0 2.4e-52 176.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFH40748.1 - 6.7e-16 58.8 0.0 1.2e-15 58.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFH40748.1 - 1.5e-06 27.6 0.0 2e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RCC1_2 PF13540.1 KFH40749.1 - 7.9e-14 50.8 7.6 1.6e-07 30.7 0.1 3.4 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 KFH40749.1 - 2.8e-10 40.2 2.6 0.00025 21.1 0.7 5.1 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat Kelch_6 PF13964.1 KFH40749.1 - 0.1 12.8 0.9 0.71 10.1 0.1 2.7 2 1 0 2 2 2 0 Kelch motif PQQ_3 PF13570.1 KFH40749.1 - 0.14 12.5 1.7 25 5.3 0.1 3.1 3 0 0 3 3 3 0 PQQ-like domain RINGv PF12906.2 KFH40751.1 - 1.4e-09 37.8 3.5 1.6e-08 34.4 0.7 2.2 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 KFH40751.1 - 0.0016 18.1 2.9 0.0068 16.2 0.7 2.1 2 0 0 2 2 2 1 Ring finger domain DoxX_3 PF13781.1 KFH40751.1 - 0.07 13.4 0.7 0.07 13.4 0.5 1.8 2 0 0 2 2 2 0 DoxX-like family zf-MIZ PF02891.15 KFH40751.1 - 0.21 11.1 2.4 0.37 10.3 1.7 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DUF202 PF02656.10 KFH40751.1 - 0.25 11.5 3.7 0.45 10.7 0.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF202) PHD PF00628.24 KFH40751.1 - 0.6 9.8 5.9 0.1 12.3 1.3 1.8 2 0 0 2 2 2 0 PHD-finger BING4CT PF08149.6 KFH40752.1 - 2e-41 139.3 0.0 2.2e-37 126.4 0.0 3.3 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.27 KFH40752.1 - 1.3e-07 31.2 0.0 0.00078 19.2 0.0 3.8 5 0 0 5 5 5 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KFH40752.1 - 0.0011 17.9 0.0 0.0042 15.9 0.0 1.8 1 1 0 2 2 2 1 Coatomer WD associated region Cytochrom_D1 PF02239.11 KFH40752.1 - 0.065 11.5 0.0 1.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain AAA_17 PF13207.1 KFH40753.1 - 1.2e-06 29.3 0.1 5.9e-06 27.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KFH40753.1 - 0.00014 22.1 0.0 0.00095 19.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain CPT PF07931.7 KFH40753.1 - 0.00044 19.9 0.0 0.00089 18.9 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein PRK PF00485.13 KFH40753.1 - 0.0035 16.9 0.0 0.0065 16.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.7 KFH40753.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 KFH40753.1 - 0.04 13.8 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain CoaE PF01121.15 KFH40753.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase ABC_tran PF00005.22 KFH40753.1 - 0.16 12.2 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Pyridoxal_deC PF00282.14 KFH40754.1 - 1e-19 70.2 0.0 1.5e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KFH40754.1 - 5.2e-06 25.4 0.0 7.5e-06 24.9 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KFH40754.1 - 0.00052 19.1 0.1 0.00079 18.5 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aa_trans PF01490.13 KFH40756.1 - 7.3e-65 219.0 25.9 8.8e-65 218.7 17.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF663 PF04950.7 KFH40757.1 - 3.2e-104 348.0 0.0 4.4e-104 347.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KFH40757.1 - 4.2e-19 67.8 0.0 9.2e-19 66.7 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Proteasome PF00227.21 KFH40758.1 - 8.3e-56 188.2 0.1 5.5e-33 113.8 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 KFH40758.1 - 2e-11 43.0 0.3 4.2e-11 41.9 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature BCDHK_Adom3 PF10436.4 KFH40759.1 - 6.2e-70 233.9 0.0 1.1e-69 233.1 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KFH40759.1 - 1.5e-17 63.3 0.0 3.3e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KFH40759.1 - 0.027 14.1 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sorb PF02208.11 KFH40759.1 - 0.052 12.9 0.0 0.42 10.0 0.0 2.4 2 0 0 2 2 2 0 Sorbin homologous domain Stc1 PF12898.2 KFH40760.1 - 2.7e-06 27.3 0.2 4.4e-06 26.6 0.2 1.2 1 0 0 1 1 1 1 Stc1 domain PTH2 PF01981.11 KFH40761.1 - 5.5e-47 158.2 0.1 7.2e-47 157.8 0.1 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Ribonuclease_3 PF00636.21 KFH40762.1 - 2.3e-42 144.0 0.0 2e-20 73.3 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KFH40762.1 - 1.5e-25 89.6 0.0 8.8e-12 45.0 0.0 3.6 3 0 0 3 3 3 3 Ribonuclease-III-like DEAD PF00270.24 KFH40762.1 - 1.7e-18 66.6 0.0 5.8e-18 64.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Dicer_dimer PF03368.9 KFH40762.1 - 1.4e-16 60.0 0.0 3e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.26 KFH40762.1 - 5.4e-15 55.0 0.1 1.1e-14 54.0 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFH40762.1 - 1.1e-07 31.8 0.0 2.7e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 KFH40762.1 - 0.21 10.8 0.0 0.43 9.8 0.0 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain Glyco_transf_34 PF05637.7 KFH40764.1 - 3.4e-69 232.9 0.0 4.3e-69 232.6 0.0 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 KFH40764.1 - 0.021 14.1 0.0 0.13 11.5 0.0 1.9 1 1 0 2 2 2 0 Protein of unknown function, DUF273 Ras PF00071.17 KFH40765.1 - 5.4e-56 188.4 0.0 6.2e-56 188.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFH40765.1 - 1.7e-15 57.5 0.0 2.7e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFH40765.1 - 2.5e-07 30.0 0.0 4.1e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KFH40765.1 - 0.0023 17.1 0.0 0.0031 16.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KFH40765.1 - 0.02 14.0 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region cobW PF02492.14 KFH40766.1 - 2e-34 118.5 0.0 2.6e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 KFH40766.1 - 8.9e-05 21.3 1.2 0.0015 17.3 0.8 2.0 1 1 0 1 1 1 1 ArgK protein AAA_23 PF13476.1 KFH40766.1 - 0.0089 16.3 0.0 0.012 15.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 KFH40766.1 - 0.026 14.4 0.0 0.079 12.9 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase ResIII PF04851.10 KFH40766.1 - 0.033 14.0 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_17 PF13207.1 KFH40766.1 - 0.055 14.3 0.3 0.12 13.1 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFH40766.1 - 0.092 12.1 0.6 0.2 11.0 0.2 1.5 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KFH40766.1 - 0.13 11.6 0.0 0.38 10.1 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.1 KFH40766.1 - 0.14 12.4 0.0 0.34 11.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.1 KFH40766.1 - 0.16 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain TMEM51 PF15345.1 KFH40766.1 - 0.16 11.6 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 DSPc PF00782.15 KFH40767.1 - 1.2e-13 50.8 0.0 4.7e-07 29.4 0.0 3.1 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Rtt106 PF08512.7 KFH40768.1 - 2.6e-22 78.6 0.0 7e-22 77.2 0.0 1.7 2 0 0 2 2 2 1 Histone chaperone Rttp106-like CENP-T PF15511.1 KFH40768.1 - 1.8 7.7 28.4 2.8 7.0 19.7 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF1510 PF07423.6 KFH40768.1 - 3.5 6.9 17.7 5.2 6.3 12.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) zf-C2H2_4 PF13894.1 KFH40769.1 - 0.00011 22.2 22.4 0.015 15.5 1.0 4.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KFH40769.1 - 0.002 18.3 28.1 0.0074 16.5 0.9 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFH40769.1 - 0.0028 17.8 1.1 0.0028 17.8 0.8 4.2 4 1 1 5 5 5 1 Zinc-finger double domain zf-CHCC PF10276.4 KFH40769.1 - 0.0029 17.3 4.6 1 9.2 0.6 2.5 2 0 0 2 2 2 2 Zinc-finger domain PyrI_C PF02748.10 KFH40769.1 - 0.12 11.8 4.8 8.9 5.8 2.8 2.5 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_jaz PF12171.3 KFH40769.1 - 4.4 7.5 19.2 0.077 13.1 2.1 4.0 3 1 1 4 4 4 0 Zinc-finger double-stranded RNA-binding DUF1903 PF08991.5 KFH40770.1 - 0.05 13.7 0.2 0.074 13.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) Snf7 PF03357.16 KFH40771.1 - 3.1e-40 137.3 9.1 3.6e-40 137.1 6.3 1.0 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.7 KFH40771.1 - 8.4e-05 22.7 5.5 0.012 15.8 1.1 2.9 1 1 2 3 3 3 1 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.4 KFH40771.1 - 0.00044 20.1 14.2 0.0071 16.1 9.5 2.3 2 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 KFH40771.1 - 0.0037 16.4 1.7 0.021 14.0 0.4 1.9 1 1 1 2 2 2 1 Reovirus sigma C capsid protein DUF2205 PF10224.4 KFH40771.1 - 0.022 14.3 3.2 0.022 14.3 2.2 3.1 1 1 1 3 3 3 0 Predicted coiled-coil protein (DUF2205) Zwint PF15556.1 KFH40771.1 - 0.022 14.0 8.6 0.029 13.6 6.0 1.3 1 0 0 1 1 1 0 ZW10 interactor Exonuc_VII_L PF02601.10 KFH40771.1 - 0.022 13.9 4.4 0.029 13.5 3.0 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit NuA4 PF09340.5 KFH40771.1 - 0.025 14.2 2.8 0.051 13.2 1.9 1.6 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 MitMem_reg PF13012.1 KFH40771.1 - 0.026 14.6 5.2 0.15 12.1 3.5 2.1 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Lipase_chap PF03280.9 KFH40771.1 - 0.047 13.2 6.3 0.075 12.5 4.3 1.4 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein Sec34 PF04136.10 KFH40771.1 - 0.058 13.0 4.9 1.4 8.6 1.7 2.2 1 1 1 2 2 2 0 Sec34-like family Glutaredoxin PF00462.19 KFH40771.1 - 0.097 12.6 1.3 1.6 8.7 0.1 2.8 2 1 1 3 3 3 0 Glutaredoxin APG6 PF04111.7 KFH40771.1 - 0.16 10.9 14.1 0.038 13.0 7.8 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF848 PF05852.6 KFH40771.1 - 0.17 11.7 9.0 0.18 11.6 4.5 2.2 1 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) NYD-SP28_assoc PF14775.1 KFH40771.1 - 0.18 11.5 6.3 1.6 8.4 1.0 3.2 2 1 1 3 3 3 0 Sperm tail C-terminal domain Peptidase_S46 PF10459.4 KFH40771.1 - 0.18 10.2 7.3 0.22 9.8 5.1 1.0 1 0 0 1 1 1 0 Peptidase S46 Baculo_PEP_C PF04513.7 KFH40771.1 - 0.23 11.2 3.9 1.3 8.8 1.4 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Atg14 PF10186.4 KFH40771.1 - 0.34 9.8 7.5 0.45 9.4 5.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF972 PF06156.8 KFH40771.1 - 0.39 11.0 10.4 6.1 7.2 4.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF4407 PF14362.1 KFH40771.1 - 0.44 9.4 5.0 0.59 9.0 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IncA PF04156.9 KFH40771.1 - 0.45 10.0 9.7 0.53 9.8 3.9 2.3 1 1 1 2 2 2 0 IncA protein AAA_13 PF13166.1 KFH40771.1 - 0.63 8.4 9.2 1.2 7.5 6.2 1.5 1 1 0 1 1 1 0 AAA domain Allexi_40kDa PF05549.6 KFH40771.1 - 0.65 9.2 3.9 5.6 6.1 0.0 2.3 1 1 0 2 2 2 0 Allexivirus 40kDa protein Mod_r PF07200.8 KFH40771.1 - 0.68 9.8 13.7 0.2 11.5 5.3 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Laminin_II PF06009.7 KFH40771.1 - 0.88 9.3 8.8 3.1 7.5 4.2 2.2 1 1 1 2 2 2 0 Laminin Domain II Spore_III_AF PF09581.5 KFH40771.1 - 0.98 9.2 7.2 1.4 8.7 5.0 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) COG2 PF06148.6 KFH40771.1 - 1.3 8.8 8.8 1.2 9.0 3.0 2.7 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF342 PF03961.8 KFH40771.1 - 1.6 7.0 11.3 2.7 6.2 4.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Mnd1 PF03962.10 KFH40771.1 - 1.7 8.2 12.4 6.1 6.4 8.4 1.9 1 1 0 1 1 1 0 Mnd1 family FliD_N PF02465.13 KFH40771.1 - 2.9 8.2 8.3 46 4.4 4.1 2.7 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus OmpH PF03938.9 KFH40771.1 - 3 7.7 18.4 0.59 10.0 7.7 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF2408 PF10303.4 KFH40771.1 - 3.7 7.6 9.8 16 5.6 6.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) DUF4446 PF14584.1 KFH40771.1 - 6.5 6.5 9.6 5.6 6.7 0.7 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) DUF4337 PF14235.1 KFH40771.1 - 6.5 6.5 10.3 1.8 8.3 4.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) FlaC_arch PF05377.6 KFH40771.1 - 8 6.4 8.6 16 5.4 1.5 3.5 3 1 0 3 3 2 0 Flagella accessory protein C (FlaC) DUF2730 PF10805.3 KFH40771.1 - 8.6 6.1 8.5 19 5.0 2.3 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF2730) Vfa1 PF08432.5 KFH40775.1 - 1.7e-50 171.5 28.7 2.4e-49 167.8 19.9 1.9 1 1 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Ycf1 PF05758.7 KFH40775.1 - 0.87 7.2 10.8 0.99 7.0 7.5 1.1 1 0 0 1 1 1 0 Ycf1 Borrelia_P83 PF05262.6 KFH40775.1 - 1.7 6.8 14.7 1.9 6.6 10.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein CDC45 PF02724.9 KFH40775.1 - 2.6 5.9 16.5 3.3 5.6 11.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4246 PF14033.1 KFH40775.1 - 3.5 6.1 11.1 5.1 5.5 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) SAPS PF04499.10 KFH40775.1 - 3.9 6.0 9.5 4.8 5.7 6.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FAM176 PF14851.1 KFH40775.1 - 4 7.1 7.4 7.2 6.2 5.2 1.6 1 0 0 1 1 1 0 FAM176 family Spc24 PF08286.6 KFH40775.1 - 7.6 6.2 11.5 88 2.8 9.1 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 TPR_12 PF13424.1 KFH40776.1 - 1.1e-09 38.1 5.1 0.0025 17.7 0.3 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFH40776.1 - 6.7e-07 28.8 6.8 1.8e-05 24.2 0.0 4.1 2 2 1 4 4 4 1 TPR repeat TPR_2 PF07719.12 KFH40776.1 - 1e-05 25.0 9.6 0.021 14.7 0.0 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFH40776.1 - 1.5e-05 25.5 8.5 0.00019 22.0 0.6 4.4 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFH40776.1 - 0.00018 21.8 5.8 0.85 10.4 0.2 5.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFH40776.1 - 0.00018 20.9 3.3 0.04 13.5 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFH40776.1 - 0.00024 20.6 0.6 1.8 8.5 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat Ank_2 PF12796.2 KFH40776.1 - 0.00047 20.4 0.0 0.0015 18.8 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) TPR_19 PF14559.1 KFH40776.1 - 0.00048 20.4 0.6 0.0081 16.4 0.1 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 KFH40776.1 - 0.0014 18.5 8.5 0.76 9.7 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat Ank_4 PF13637.1 KFH40776.1 - 0.0056 17.1 0.0 0.018 15.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) TPR_17 PF13431.1 KFH40776.1 - 0.0072 16.4 0.0 0.3 11.3 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFH40776.1 - 0.009 15.7 0.1 11 6.0 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat MAS20 PF02064.10 KFH40776.1 - 0.048 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 MAS20 protein import receptor HET PF06985.6 KFH40776.1 - 0.075 13.1 0.1 0.21 11.7 0.1 1.8 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) Aminotran_3 PF00202.16 KFH40776.1 - 0.1 11.4 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III GGDEF PF00990.16 KFH40776.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 GGDEF domain TPR_4 PF07721.9 KFH40776.1 - 3.3 8.4 10.2 2.8 8.6 0.1 4.8 5 0 0 5 5 3 0 Tetratricopeptide repeat WD40 PF00400.27 KFH40777.1 - 2.1e-34 116.1 13.0 2.9e-06 26.9 0.0 8.8 9 0 0 9 9 9 6 WD domain, G-beta repeat F-box-like PF12937.2 KFH40777.1 - 4.6e-13 48.6 4.1 1.1e-12 47.4 2.9 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFH40777.1 - 5.9e-05 22.6 2.3 5.9e-05 22.6 1.6 1.8 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.3 KFH40777.1 - 0.00011 20.4 0.1 0.19 9.8 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 SmpA_OmlA PF04355.8 KFH40777.1 - 0.16 11.5 0.2 2.6 7.7 0.1 2.5 2 0 0 2 2 2 0 SmpA / OmlA family PH_10 PF15411.1 KFH40778.1 - 1.8e-41 140.9 0.0 3.4e-41 140.0 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 KFH40778.1 - 1.3e-31 109.8 0.1 2.2e-31 109.1 0.1 1.3 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.6 KFH40778.1 - 2.5e-28 97.9 0.1 5e-28 96.9 0.1 1.5 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.19 KFH40778.1 - 7e-08 32.0 0.0 1.8e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 PB1 domain PH PF00169.24 KFH40778.1 - 0.0078 16.3 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 PH domain Glyco_hydro_18 PF00704.23 KFH40781.1 - 1e-53 183.0 2.3 1.9e-53 182.1 1.6 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 KFH40781.1 - 1.5e-11 44.0 0.4 0.0002 21.1 0.0 2.8 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 KFH40781.1 - 1.7e-06 27.9 3.1 1.7e-06 27.9 2.2 3.7 4 0 0 4 4 4 1 Chitin recognition protein DUF3142 PF11340.3 KFH40781.1 - 0.0075 15.9 0.1 0.022 14.3 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3142) Glyco_transf_28 PF03033.15 KFH40782.1 - 6.6e-18 64.8 0.1 1.5e-17 63.6 0.1 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KFH40782.1 - 0.00045 18.8 0.0 0.0007 18.2 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KFH40782.1 - 0.0075 15.9 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain NYN PF01936.13 KFH40784.1 - 2.4e-06 27.8 0.0 2.5e-05 24.6 0.0 2.2 1 1 0 1 1 1 1 NYN domain Fungal_trans_2 PF11951.3 KFH40785.1 - 5.2e-06 25.3 0.1 7.3e-06 24.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH40785.1 - 0.001 18.9 3.1 0.0026 17.6 2.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0175 PF03683.8 KFH40786.1 - 0.0081 15.6 0.1 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0175) DUF2993 PF11209.3 KFH40786.1 - 0.072 12.9 0.2 1.2 9.0 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2993) Alkyl_sulf_C PF14864.1 KFH40786.1 - 0.11 12.4 0.9 0.58 10.1 0.0 2.3 2 0 0 2 2 2 0 Alkyl sulfatase C-terminal RhoGAP PF00620.22 KFH40787.1 - 3.9e-46 156.4 3.0 4.8e-46 156.1 0.0 2.7 2 2 1 3 3 3 1 RhoGAP domain LIM PF00412.17 KFH40787.1 - 1.3e-13 50.7 16.1 3.9e-09 36.4 1.2 2.4 2 0 0 2 2 2 2 LIM domain Desulfoferrod_N PF06397.7 KFH40787.1 - 0.11 11.9 7.3 4.6 6.7 0.4 3.5 2 1 1 3 3 3 0 Desulfoferrodoxin, N-terminal domain Zn-ribbon_8 PF09723.5 KFH40787.1 - 0.47 10.4 15.8 1.9 8.4 0.4 4.3 4 0 0 4 4 4 0 Zinc ribbon domain zinc_ribbon_2 PF13240.1 KFH40787.1 - 0.51 9.9 0.0 0.51 9.9 0.0 4.7 5 1 0 5 5 5 0 zinc-ribbon domain CCDC155 PF14662.1 KFH40787.1 - 3.7 7.0 23.0 4.6 6.7 7.8 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 PPR_2 PF13041.1 KFH40788.1 - 8e-18 64.1 9.3 4.9e-05 23.2 0.0 7.6 4 2 3 7 7 7 4 PPR repeat family PPR PF01535.15 KFH40788.1 - 3.4e-16 58.0 15.8 0.002 17.9 0.2 8.8 9 0 0 9 9 9 4 PPR repeat PPR_3 PF13812.1 KFH40788.1 - 5.7e-16 57.3 4.7 0.44 10.9 0.0 9.4 9 0 0 9 9 9 4 Pentatricopeptide repeat domain PPR_1 PF12854.2 KFH40788.1 - 3.6e-05 23.1 1.9 11 5.6 0.0 5.8 6 0 0 6 6 6 1 PPR repeat Cytomega_gL PF01801.11 KFH40788.1 - 0.008 15.6 0.4 0.017 14.6 0.3 1.4 1 0 0 1 1 1 1 Cytomegalovirus glycoprotein L SPOB_a PF14689.1 KFH40788.1 - 0.013 15.0 0.7 0.2 11.2 0.0 3.4 4 0 0 4 4 4 0 Sensor_kinase_SpoOB-type, alpha-helical domain ATP13 PF12921.2 KFH40788.1 - 0.055 12.8 0.1 1.3 8.3 0.0 3.2 3 0 0 3 3 3 0 Mitochondrial ATPase expression PBP_sp32 PF07222.7 KFH40788.1 - 0.73 8.9 12.7 1.2 8.2 8.8 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 PI3_PI4_kinase PF00454.22 KFH40789.1 - 1e-40 139.6 0.0 1.4e-40 139.2 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase CLASP_N PF12348.3 KFH40790.1 - 9.5e-126 417.6 0.3 1.7e-83 279.4 0.0 3.7 4 0 0 4 4 4 2 CLASP N terminal HEAT PF02985.17 KFH40790.1 - 6.5e-07 28.9 2.7 0.63 10.2 0.0 5.0 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.1 KFH40790.1 - 4.4e-05 23.6 5.4 0.1 12.8 0.2 5.2 3 2 1 4 4 4 1 HEAT repeats MMS19_C PF12460.3 KFH40790.1 - 8.1e-05 21.5 3.9 0.00048 18.9 0.2 2.8 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal DUF2999 PF11212.3 KFH40790.1 - 0.025 14.6 0.1 0.14 12.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2999) Adaptin_N PF01602.15 KFH40790.1 - 0.059 11.6 2.3 0.31 9.3 0.0 3.1 5 0 0 5 5 5 0 Adaptin N terminal region HEAT_EZ PF13513.1 KFH40790.1 - 0.15 12.6 4.3 13 6.4 0.0 4.9 5 0 0 5 5 5 0 HEAT-like repeat Alginate_lyase PF05426.7 KFH40791.1 - 0.021 14.1 1.1 0.037 13.3 0.8 1.4 1 0 0 1 1 1 0 Alginate lyase rRNA_processing PF08524.6 KFH40792.1 - 2.5e-06 27.3 29.7 0.00088 19.0 4.7 2.1 1 1 1 2 2 2 2 rRNA processing DUF4210 PF13915.1 KFH40793.1 - 6.8e-27 93.5 0.1 1.4e-26 92.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 KFH40793.1 - 5.3e-20 71.0 0.2 1.3e-19 69.8 0.1 1.7 1 0 0 1 1 1 1 Chromosome segregation during meiosis Colicin_C PF12106.3 KFH40794.1 - 3.4 7.3 5.7 0.48 10.0 0.8 1.8 2 0 0 2 2 2 0 Colicin C terminal ribonuclease domain BSP PF04450.7 KFH40795.1 - 1.4e-75 253.2 0.0 1.6e-75 253.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 KFH40795.1 - 8.6e-09 35.5 0.4 2.4e-06 27.6 0.0 2.3 1 1 1 2 2 2 2 Peptidase MA superfamily SprT-like PF10263.4 KFH40795.1 - 0.0013 18.4 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 SprT-like family HEAT_EZ PF13513.1 KFH40796.1 - 6.4 7.4 11.5 0.99 9.9 1.9 3.7 4 1 0 4 4 4 0 HEAT-like repeat DUF3632 PF12311.3 KFH40797.1 - 2e-23 83.1 0.3 2.7e-23 82.7 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) FlaF PF07309.6 KFH40797.1 - 0.12 12.2 1.7 0.16 11.8 0.0 2.0 3 1 0 3 3 3 0 Flagellar protein FlaF 2-oxoacid_dh PF00198.18 KFH40798.1 - 6e-77 258.0 0.1 7.6e-77 257.6 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KFH40798.1 - 1.7e-19 69.2 1.0 4.1e-19 67.9 0.7 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KFH40798.1 - 3.3e-14 52.2 0.4 7.7e-14 51.0 0.3 1.7 1 0 0 1 1 1 1 e3 binding domain Nucleoporin_FG PF13634.1 KFH40799.1 - 1.1e-18 67.5 198.0 4e-12 46.3 45.2 4.3 2 1 2 4 4 4 3 Nucleoporin FG repeat region Fzo_mitofusin PF04799.8 KFH40799.1 - 0.11 11.8 0.1 0.39 10.0 0.0 1.9 2 1 1 3 3 3 0 fzo-like conserved region Vps53_N PF04100.7 KFH40799.1 - 0.11 11.2 1.0 0.17 10.6 0.7 1.2 1 0 0 1 1 1 0 Vps53-like, N-terminal DUF4455 PF14643.1 KFH40799.1 - 0.15 10.6 0.3 11 4.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4455) Methyltransf_11 PF08241.7 KFH40800.1 - 7.5e-08 32.7 0.0 1.3e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH40800.1 - 2.2e-07 31.4 0.0 3.4e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH40800.1 - 7.2e-07 29.6 0.0 1.5e-06 28.5 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH40800.1 - 3.3e-06 26.9 0.0 4.7e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH40800.1 - 1.4e-05 24.7 0.0 1.9e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFH40800.1 - 0.00073 19.8 0.0 0.0013 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFH40800.1 - 0.0063 15.9 0.0 0.012 15.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KFH40800.1 - 0.0074 16.3 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 KFH40800.1 - 0.018 14.9 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase Pam17 PF08566.5 KFH40801.1 - 1.4 8.5 3.6 1.1 8.8 0.3 1.9 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 Fip1 PF05182.8 KFH40802.1 - 1.5e-20 72.1 1.1 3.1e-20 71.1 0.7 1.5 1 0 0 1 1 1 1 Fip1 motif RAP1 PF07218.6 KFH40802.1 - 7.5 4.5 7.3 11 4.0 5.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Lipoxygenase PF00305.14 KFH40803.1 - 0.14 10.1 0.0 0.18 9.7 0.0 1.1 1 0 0 1 1 1 0 Lipoxygenase RNA_pol_3_Rpc31 PF11705.3 KFH40804.1 - 8.1e-35 120.8 11.2 2.1e-34 119.5 7.8 1.6 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Sec7 PF01369.15 KFH40805.1 - 5.2e-63 212.1 0.4 5.2e-63 212.1 0.3 3.1 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.2 KFH40805.1 - 1.4e-50 170.9 2.7 1.4e-50 170.9 1.9 2.9 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KFH40805.1 - 2.8e-31 106.8 5.2 9.2e-31 105.2 0.0 3.9 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) Cut8_N PF14482.1 KFH40805.1 - 0.0045 16.9 0.3 0.019 14.9 0.2 2.1 1 0 0 1 1 1 1 Cut8 proteasome-binding domain DUF2456 PF10445.4 KFH40806.1 - 6.8e-18 64.3 0.3 6.5e-17 61.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2456) DUF1446 PF07287.6 KFH40808.1 - 1.9e-128 427.9 0.5 2.3e-128 427.7 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) FAD_binding_4 PF01565.18 KFH40809.1 - 2.8e-17 62.4 0.8 4.7e-17 61.7 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.9 KFH40809.1 - 2.1e-11 43.9 0.4 1e-10 41.6 0.3 1.9 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase Glyoxalase_2 PF12681.2 KFH40809.1 - 0.065 13.8 0.0 5.1 7.7 0.0 2.8 3 0 0 3 3 3 0 Glyoxalase-like domain FAD-oxidase_C PF02913.14 KFH40809.1 - 0.12 11.6 0.1 7.5 5.7 0.0 2.4 3 0 0 3 3 3 0 FAD linked oxidases, C-terminal domain Fungal_trans PF04082.13 KFH40810.1 - 2.5e-16 59.3 0.2 6.7e-16 57.9 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH40810.1 - 0.0001 22.1 13.7 0.00019 21.2 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RAP1 PF07218.6 KFH40810.1 - 4.6 5.2 6.7 6.9 4.6 4.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Frag1 PF10277.4 KFH40811.1 - 1.9e-15 56.9 9.7 2.4e-15 56.6 6.7 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF998 PF06197.8 KFH40811.1 - 0.00023 20.5 10.9 0.00063 19.1 7.6 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF998) DUF2834 PF11196.3 KFH40811.1 - 0.12 12.5 2.4 8.5 6.6 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2834) DUF2273 PF10031.4 KFH40811.1 - 0.15 11.6 2.1 7.9 6.1 0.0 3.0 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) MFS_2 PF13347.1 KFH40811.1 - 0.39 9.0 11.7 1.1 7.5 8.1 1.7 1 1 0 1 1 1 0 MFS/sugar transport protein Glyco_hydro_61 PF03443.9 KFH40812.1 - 1.7e-77 260.1 0.0 2.3e-77 259.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Sulfate_transp PF00916.15 KFH40813.1 - 1.4e-72 244.0 8.2 2.5e-72 243.2 5.7 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KFH40813.1 - 1.9e-30 104.3 3.0 1.9e-30 104.3 2.1 3.8 5 0 0 5 5 5 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KFH40813.1 - 3.1e-07 29.8 0.0 5.8e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 KFH40813.1 - 0.047 13.7 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 STAS domain Chromo PF00385.19 KFH40815.1 - 2.7e-14 52.5 2.4 5.9e-06 25.8 0.5 2.6 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Plus-3 PF03126.13 KFH40816.1 - 5.9e-27 93.8 0.0 1.9e-26 92.1 0.0 1.9 2 0 0 2 2 2 1 Plus-3 domain Brix PF04427.13 KFH40817.1 - 2.5e-47 161.0 0.0 3.4e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 Brix domain SNARE PF05739.14 KFH40818.1 - 4.8e-13 48.5 1.1 1.6e-12 46.9 0.8 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 KFH40818.1 - 6.5e-11 42.3 5.1 6.5e-11 42.3 3.5 2.3 2 0 0 2 2 2 1 Syntaxin DUF4094 PF13334.1 KFH40818.1 - 0.022 15.1 1.8 1.4 9.3 0.0 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) Allexi_40kDa PF05549.6 KFH40818.1 - 0.16 11.2 6.3 0.15 11.2 1.0 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF2077 PF09850.4 KFH40818.1 - 0.22 10.8 0.1 0.22 10.8 0.0 2.1 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) Peptidase_C6 PF00851.13 KFH40818.1 - 0.42 9.1 5.4 0.36 9.4 1.9 1.8 1 1 1 2 2 2 0 Helper component proteinase Syntaxin_2 PF14523.1 KFH40818.1 - 1 9.4 16.1 0.2 11.6 6.0 2.6 2 1 0 2 2 2 0 Syntaxin-like protein ING PF12998.2 KFH40818.1 - 4.2 7.7 9.7 3.4 7.9 0.9 2.8 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Fib_alpha PF08702.5 KFH40818.1 - 6.7 6.8 12.5 3.4 7.7 3.9 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family F-box PF00646.28 KFH40819.1 - 6.2e-08 32.1 1.2 6.2e-08 32.1 0.8 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KFH40819.1 - 6.9e-08 32.0 3.1 2.1e-07 30.5 2.1 1.9 1 0 0 1 1 1 1 F-box-like TPR_11 PF13414.1 KFH40819.1 - 5.5e-06 25.9 1.8 0.033 13.8 0.0 3.4 2 1 1 3 3 3 2 TPR repeat TPR_14 PF13428.1 KFH40819.1 - 0.0023 18.3 3.9 0.094 13.4 1.4 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFH40819.1 - 0.011 15.5 4.9 0.53 10.3 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFH40819.1 - 0.027 15.1 9.5 0.14 12.8 0.3 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFH40819.1 - 0.028 14.0 1.9 0.45 10.2 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4475 PF14753.1 KFH40819.1 - 0.033 13.7 3.7 0.059 12.8 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4475) LRR_4 PF12799.2 KFH40819.1 - 0.059 13.0 3.2 4.6 6.9 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) TPR_12 PF13424.1 KFH40819.1 - 0.062 13.2 0.6 2.6 8.0 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat ERG4_ERG24 PF01222.12 KFH40820.1 - 7e-138 459.7 19.6 8.1e-138 459.5 13.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family SET PF00856.23 KFH40821.1 - 0.034 14.4 0.0 0.13 12.5 0.0 2.0 2 0 0 2 2 2 0 SET domain GDPD PF03009.12 KFH40823.1 - 5.8e-31 107.9 0.0 1.7e-30 106.3 0.0 1.8 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 KFH40823.1 - 0.11 12.7 4.3 4.7 7.5 0.3 2.6 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family COQ7 PF03232.8 KFH40824.1 - 1.8e-64 216.3 0.1 2.2e-64 216.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 KFH40824.1 - 0.0038 17.5 0.0 0.0068 16.7 0.0 1.6 1 1 0 1 1 1 1 Rubrerythrin Glyco_hydro_47 PF01532.15 KFH40825.1 - 3.5e-163 543.4 0.1 4e-163 543.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 UPF1_Zn_bind PF09416.5 KFH40826.1 - 3e-69 231.4 4.6 3e-69 231.4 3.2 2.1 3 0 0 3 3 3 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 KFH40826.1 - 2.8e-61 206.3 0.0 9.2e-61 204.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KFH40826.1 - 4.3e-58 196.6 1.8 6.9e-58 195.9 1.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFH40826.1 - 1e-13 50.8 0.1 2.7e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KFH40826.1 - 2.3e-11 43.6 0.1 1.2e-09 38.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KFH40826.1 - 2.2e-06 27.6 0.0 4.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KFH40826.1 - 0.00016 21.3 0.0 0.62 9.5 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 KFH40826.1 - 0.00058 19.5 0.0 0.0015 18.2 0.0 1.7 1 0 0 1 1 1 1 Helicase DUF2075 PF09848.4 KFH40826.1 - 0.00087 18.3 1.6 0.0036 16.3 0.1 2.4 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.9 KFH40826.1 - 0.00098 18.1 0.2 0.17 10.8 0.0 2.3 1 1 1 2 2 2 2 PIF1-like helicase DEAD PF00270.24 KFH40826.1 - 0.0022 17.5 0.1 0.0045 16.4 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase UvrD-helicase PF00580.16 KFH40826.1 - 0.0038 16.5 0.0 0.018 14.3 0.0 2.0 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain KaiC PF06745.8 KFH40826.1 - 0.021 13.9 0.0 0.11 11.6 0.0 1.9 2 0 0 2 2 2 0 KaiC Ribosomal_S13_N PF08069.7 KFH40826.1 - 0.042 13.6 0.0 0.096 12.5 0.0 1.6 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain SRP54 PF00448.17 KFH40826.1 - 0.076 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA PF00004.24 KFH40826.1 - 0.19 11.9 0.0 0.41 10.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TPR_11 PF13414.1 KFH40827.1 - 2.2e-54 180.9 24.4 5.9e-14 51.4 0.3 7.1 3 3 4 8 8 8 8 TPR repeat TPR_2 PF07719.12 KFH40827.1 - 1.4e-44 146.4 15.0 5.1e-05 22.8 0.0 11.5 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_1 PF00515.23 KFH40827.1 - 1.6e-43 144.5 16.2 7e-06 25.4 0.0 11.3 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_16 PF13432.1 KFH40827.1 - 1.8e-31 108.1 3.8 3.3e-05 24.4 0.3 6.5 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.1 KFH40827.1 - 3.2e-29 98.6 4.7 4e-06 26.6 0.0 9.2 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_12 PF13424.1 KFH40827.1 - 1e-26 92.6 15.9 9.1e-09 35.1 0.0 7.2 2 2 6 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.1 KFH40827.1 - 1.6e-18 65.0 13.4 0.009 15.7 0.1 10.1 9 1 1 10 10 10 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFH40827.1 - 4.1e-17 61.1 10.2 0.0062 17.0 0.4 9.8 3 3 8 11 11 11 5 Tetratricopeptide repeat TPR_19 PF14559.1 KFH40827.1 - 1.5e-15 57.2 14.3 0.00013 22.2 0.4 6.3 4 2 3 7 7 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 KFH40827.1 - 5.9e-13 48.4 5.6 0.00011 22.0 0.1 6.4 3 2 4 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.1 KFH40827.1 - 1.7e-10 39.8 13.0 0.17 11.7 0.0 8.9 10 0 0 10 10 10 2 Tetratricopeptide repeat Apc3 PF12895.2 KFH40827.1 - 3.9e-10 39.7 9.6 0.33 11.1 0.1 5.6 2 1 3 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KFH40827.1 - 7.9e-06 25.9 22.9 0.11 12.9 0.0 9.5 11 0 0 11 11 10 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 KFH40827.1 - 0.0015 17.7 2.2 6.9 6.0 0.0 4.5 4 0 0 4 4 4 2 SHNi-TPR TPR_4 PF07721.9 KFH40827.1 - 0.053 13.9 2.9 19 6.0 0.0 5.3 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 KFH40827.1 - 0.055 13.4 9.7 10 6.2 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat MAS20 PF02064.10 KFH40827.1 - 0.14 12.0 6.1 15 5.5 0.0 4.4 5 0 0 5 5 5 0 MAS20 protein import receptor DUF2561 PF10812.3 KFH40827.1 - 0.21 11.1 1.4 0.4 10.2 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) NARP1 PF12569.3 KFH40827.1 - 0.22 10.2 23.1 0.2 10.3 0.1 4.4 2 2 2 4 4 4 0 NMDA receptor-regulated protein 1 TPR_20 PF14561.1 KFH40827.1 - 0.32 11.1 10.1 6.4 6.9 0.1 4.4 5 0 0 5 5 3 0 Tetratricopeptide repeat Sel1 PF08238.7 KFH40827.1 - 10 6.9 15.6 9.8 6.9 0.1 4.6 5 0 0 5 5 3 0 Sel1 repeat Aminotran_4 PF01063.14 KFH40828.1 - 4.5e-27 94.9 0.0 6.2e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV MMR_HSR1_C PF08438.5 KFH40829.1 - 1.1e-32 112.4 0.0 2.4e-32 111.4 0.0 1.6 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 KFH40829.1 - 3.3e-15 56.0 0.0 1.1e-14 54.4 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFH40829.1 - 4.7e-06 25.9 0.1 0.00015 21.1 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KFH40829.1 - 0.00071 19.0 0.4 1 8.7 0.0 2.9 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KFH40829.1 - 0.0015 18.3 0.3 0.23 11.2 0.1 3.0 3 0 0 3 3 3 1 Dynamin family ArgK PF03308.11 KFH40829.1 - 0.033 12.9 0.1 0.14 10.8 0.0 2.0 2 0 0 2 2 2 0 ArgK protein ABC_tran PF00005.22 KFH40829.1 - 0.066 13.5 0.0 0.38 11.0 0.0 2.0 2 0 0 2 2 2 0 ABC transporter ATP_bind_1 PF03029.12 KFH40829.1 - 0.088 12.3 0.2 5.5 6.4 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PLDc PF00614.17 KFH40830.1 - 4.2e-18 64.5 1.2 2e-08 33.7 0.3 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KFH40830.1 - 7.2e-12 45.1 0.0 1.9e-07 30.8 0.0 2.6 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 KFH40830.1 - 8.6e-07 28.7 0.0 3.1e-06 26.9 0.0 2.0 1 0 0 1 1 1 1 PX domain Fungal_trans PF04082.13 KFH40831.1 - 4.4e-31 107.6 0.3 7.4e-31 106.9 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH40831.1 - 4.6e-10 39.2 11.0 9.8e-10 38.1 7.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Utp21 PF04192.7 KFH40832.1 - 7.6e-80 267.4 0.0 1.1e-79 266.9 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 KFH40832.1 - 1.3e-25 88.2 16.6 1.7e-07 30.8 0.2 7.8 8 0 0 8 8 8 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KFH40832.1 - 8.4e-07 27.6 0.0 2.3e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nup160 PF11715.3 KFH40832.1 - 2.1e-05 22.9 0.1 0.58 8.2 0.0 3.3 3 0 0 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFH40832.1 - 0.062 12.0 0.0 6.2 5.4 0.0 2.6 1 1 0 2 2 2 0 Nup133 N terminal like GTP1_OBG PF01018.17 KFH40833.1 - 3.5e-40 137.2 2.1 6.5e-28 97.3 2.2 2.3 1 1 1 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 KFH40833.1 - 5.3e-21 74.7 0.0 8.4e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFH40833.1 - 2.7e-06 26.7 0.1 6.9e-06 25.4 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B ArgK PF03308.11 KFH40833.1 - 0.00029 19.7 0.0 0.11 11.2 0.0 2.3 2 0 0 2 2 2 2 ArgK protein GTP_EFTU PF00009.22 KFH40833.1 - 0.0053 16.2 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Arf PF00025.16 KFH40833.1 - 0.024 13.8 0.0 0.33 10.1 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family ABC_tran PF00005.22 KFH40833.1 - 0.026 14.7 0.0 0.05 13.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 KFH40833.1 - 0.17 11.3 0.0 6.6 6.2 0.0 2.4 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TFCD_C PF12612.3 KFH40835.1 - 2.8e-30 105.2 0.1 2.8e-30 105.2 0.1 2.5 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.1 KFH40835.1 - 0.0022 18.2 4.2 0.096 12.9 0.0 4.5 5 0 0 5 5 5 1 HEAT repeats HEAT PF02985.17 KFH40835.1 - 0.0072 16.3 6.9 0.81 9.9 0.0 6.2 7 0 0 7 7 7 1 HEAT repeat Vac14_Fab1_bd PF12755.2 KFH40835.1 - 0.022 15.1 0.4 1.8 9.0 0.0 2.9 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Cortex-I_coil PF09304.5 KFH40836.1 - 0.0077 16.2 12.9 0.0077 16.2 8.9 4.9 2 1 3 5 5 5 1 Cortexillin I, coiled coil Mitofilin PF09731.4 KFH40836.1 - 1.3 7.6 48.5 3.3 6.2 29.8 2.3 2 1 0 2 2 2 0 Mitochondrial inner membrane protein Prothymosin PF03247.9 KFH40837.1 - 0.022 14.8 22.8 0.038 14.1 15.8 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family Sporozoite_P67 PF05642.6 KFH40837.1 - 0.044 11.6 0.7 0.054 11.3 0.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Daxx PF03344.10 KFH40837.1 - 0.064 11.7 13.4 0.063 11.7 9.3 1.0 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 KFH40837.1 - 0.066 11.1 8.0 0.068 11.0 5.5 1.1 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 KFH40837.1 - 0.087 12.3 15.1 0.11 11.9 10.4 1.2 1 0 0 1 1 1 0 Nucleoplasmin FAM176 PF14851.1 KFH40837.1 - 0.11 12.1 2.8 0.15 11.7 1.9 1.4 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.5 KFH40837.1 - 0.17 12.1 11.5 0.3 11.3 8.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SDA1 PF05285.7 KFH40837.1 - 0.22 10.7 9.8 0.21 10.8 6.8 1.1 1 0 0 1 1 1 0 SDA1 Paf1 PF03985.8 KFH40837.1 - 0.29 9.8 8.6 0.3 9.7 6.0 1.2 1 0 0 1 1 1 0 Paf1 SLAIN PF15301.1 KFH40837.1 - 0.29 10.2 6.4 0.49 9.5 4.5 1.3 1 1 0 1 1 1 0 SLAIN motif-containing family NOA36 PF06524.7 KFH40837.1 - 0.62 9.2 5.4 0.75 8.9 3.7 1.2 1 0 0 1 1 1 0 NOA36 protein DUF3381 PF11861.3 KFH40837.1 - 0.86 9.0 10.2 1.1 8.6 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Rer1 PF03248.8 KFH40837.1 - 0.86 9.1 2.3 1.2 8.7 1.6 1.1 1 0 0 1 1 1 0 Rer1 family RNA_pol_Rpc4 PF05132.9 KFH40837.1 - 1.8 8.5 4.7 2.7 7.9 3.3 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 TRAP_alpha PF03896.11 KFH40837.1 - 2 7.3 6.0 2.6 6.9 4.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RXT2_N PF08595.6 KFH40837.1 - 3.2 7.5 8.5 5.1 6.8 5.9 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal RNA_pol_3_Rpc31 PF11705.3 KFH40837.1 - 3.7 7.4 13.3 4.8 7.0 9.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Radial_spoke PF04712.7 KFH40837.1 - 6.7 5.3 15.8 8.3 5.0 11.0 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein CDC45 PF02724.9 KFH40837.1 - 7.2 4.5 8.9 6.3 4.6 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.1 KFH40837.1 - 7.4 6.9 14.0 0.41 10.9 3.9 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal VID27 PF08553.5 KFH40837.1 - 9.4 4.3 10.9 11 4.1 7.6 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Nol1_Nop2_Fmu PF01189.12 KFH40838.1 - 8.2e-29 100.8 0.0 8.1e-19 68.0 0.0 4.2 4 1 0 4 4 4 3 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 KFH40838.1 - 0.011 15.6 0.0 0.031 14.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain His_Phos_2 PF00328.17 KFH40839.1 - 4.5e-126 420.8 0.8 5.9e-126 420.4 0.6 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 KFH40839.1 - 7.5e-06 25.5 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Zip PF02535.17 KFH40839.1 - 0.78 8.6 2.1 1.7 7.5 1.4 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter RNA_pol_Rpb5_C PF01191.14 KFH40840.1 - 2.7e-35 119.7 0.4 6e-35 118.6 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 KFH40840.1 - 8.9e-29 99.7 0.0 1.5e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 KFH40840.1 - 0.1 12.4 0.0 0.33 10.7 0.0 1.8 2 0 0 2 2 2 0 Restriction endonuclease SH3_9 PF14604.1 KFH40841.1 - 8.9e-10 38.0 0.6 1.5e-08 34.0 0.1 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KFH40841.1 - 0.014 14.8 0.1 0.033 13.6 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain SH3_1 PF00018.23 KFH40841.1 - 0.019 14.3 1.4 0.039 13.3 1.0 1.5 1 0 0 1 1 1 0 SH3 domain adh_short PF00106.20 KFH40844.1 - 3.5e-25 88.8 5.2 8.2e-25 87.6 3.8 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH40844.1 - 3.2e-21 76.2 0.1 4.1e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH40844.1 - 6.4e-13 48.7 2.1 9.6e-13 48.1 1.5 1.2 1 0 0 1 1 1 1 KR domain HEAT_EZ PF13513.1 KFH40845.1 - 4.5e-31 106.5 8.8 7.7e-14 51.6 0.0 10.9 9 2 4 13 13 13 5 HEAT-like repeat HEAT PF02985.17 KFH40845.1 - 1.8e-25 86.6 20.3 0.00018 21.2 0.0 10.6 12 0 0 12 12 10 5 HEAT repeat HEAT_2 PF13646.1 KFH40845.1 - 8.3e-23 80.4 6.2 5.5e-07 29.7 0.0 7.7 4 3 6 10 10 10 7 HEAT repeats Cnd1 PF12717.2 KFH40845.1 - 1.2e-10 41.5 0.8 0.49 10.2 0.1 6.3 5 1 1 6 6 6 3 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.3 KFH40845.1 - 3.7e-10 39.0 2.7 0.1 11.3 0.0 5.2 5 0 0 5 5 5 3 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.2 KFH40845.1 - 9.7e-10 38.7 0.4 0.099 13.0 0.0 6.6 6 2 3 9 9 8 3 Vacuolar 14 Fab1-binding region Arm PF00514.18 KFH40845.1 - 7.1e-06 25.6 5.8 0.14 11.9 0.0 6.3 8 0 0 8 8 7 2 Armadillo/beta-catenin-like repeat IBN_N PF03810.14 KFH40845.1 - 1.6e-05 24.6 2.1 0.00067 19.5 0.1 4.6 5 1 0 5 5 5 1 Importin-beta N-terminal domain Adaptin_N PF01602.15 KFH40845.1 - 0.00073 17.9 1.4 0.076 11.3 0.0 3.3 3 1 0 3 3 3 2 Adaptin N terminal region HEAT_PBS PF03130.11 KFH40845.1 - 0.0075 16.6 7.7 0.78 10.3 0.0 5.4 6 0 0 6 6 4 1 PBS lyase HEAT-like repeat DUF3437 PF11919.3 KFH40845.1 - 0.099 12.3 0.0 21 4.9 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF3437) Sec7_N PF12783.2 KFH40845.1 - 2 7.8 6.4 4.8 6.5 0.0 4.2 5 1 0 5 5 5 0 Guanine nucleotide exchange factor in Golgi transport N-terminal SPRY PF00622.23 KFH40846.1 - 6.9e-18 64.9 0.0 1.1e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 SPRY domain Zip PF02535.17 KFH40847.1 - 0.096 11.6 0.0 0.17 10.8 0.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter N2227 PF07942.7 KFH40848.1 - 1.5e-93 312.7 0.0 1.8e-93 312.4 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 KFH40848.1 - 0.00017 21.3 0.0 0.00036 20.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH40848.1 - 0.013 15.9 0.0 0.057 13.9 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 KFH40848.1 - 0.03 14.7 0.0 0.064 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_C12 PF01088.16 KFH40849.1 - 1.1e-71 240.3 0.0 1.4e-71 240.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 YodL PF14191.1 KFH40849.1 - 0.14 12.6 0.0 0.26 11.8 0.0 1.4 1 0 0 1 1 1 0 YodL-like Zn_clus PF00172.13 KFH40850.1 - 4.3e-05 23.3 8.5 7.8e-05 22.4 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFH40850.1 - 0.0071 14.9 0.1 0.012 14.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RecO_C PF02565.10 KFH40853.1 - 0.0066 16.2 0.2 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 Recombination protein O C terminal CENP-Q PF13094.1 KFH40853.1 - 0.07 13.1 0.2 0.07 13.1 0.1 2.9 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF342 PF03961.8 KFH40853.1 - 0.092 11.1 0.1 0.16 10.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TBPIP PF07106.8 KFH40853.1 - 0.18 11.3 2.4 2 7.9 0.1 3.0 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Rootletin PF15035.1 KFH40853.1 - 0.73 9.7 11.3 0.59 10.0 0.3 3.3 3 0 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion Prefoldin_2 PF01920.15 KFH40853.1 - 1.2 8.8 6.5 0.29 10.9 0.2 2.8 3 0 0 3 3 3 0 Prefoldin subunit ADIP PF11559.3 KFH40853.1 - 4.4 7.1 7.9 0.17 11.7 0.3 2.4 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding chaperone_DMP PF10448.4 KFH40855.1 - 0.016 15.1 0.0 0.028 14.2 0.0 1.6 1 1 0 1 1 1 0 20S proteasome chaperone ADH_zinc_N PF00107.21 KFH40857.1 - 1.7e-12 46.9 0.0 2.9e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFH40857.1 - 1.2e-05 25.0 0.1 4.1e-05 23.2 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain RmlD_sub_bind PF04321.12 KFH40857.1 - 0.0097 14.8 0.0 0.86 8.4 0.0 2.4 2 0 0 2 2 2 2 RmlD substrate binding domain TOBE PF03459.12 KFH40857.1 - 0.095 12.8 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 TOBE domain Band_7 PF01145.20 KFH40858.1 - 1.5e-11 44.5 0.0 1.5e-11 44.5 0.0 3.7 3 2 0 3 3 3 1 SPFH domain / Band 7 family Fringe PF02434.11 KFH40859.1 - 2.4e-07 30.2 0.0 6.6e-07 28.8 0.0 1.7 2 0 0 2 2 2 1 Fringe-like DUF604 PF04646.7 KFH40859.1 - 0.023 13.9 0.0 0.042 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF604 OmpW PF03922.9 KFH40859.1 - 0.055 13.1 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 OmpW family MFS_1 PF07690.11 KFH40860.1 - 7.1e-18 64.4 31.7 1.2e-15 57.1 15.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 KFH40860.1 - 0.00041 19.6 7.5 0.0048 16.1 0.5 3.1 3 0 0 3 3 3 2 Nodulin-like DUF4516 PF14990.1 KFH40860.1 - 0.78 9.3 6.3 0.05 13.1 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4516) Epimerase PF01370.16 KFH40862.1 - 1e-18 67.6 0.0 2.2e-18 66.5 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KFH40862.1 - 1.9e-11 43.3 0.6 1.5e-10 40.4 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 KFH40862.1 - 4.7e-07 28.9 0.5 0.0015 17.4 0.3 3.0 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KFH40862.1 - 1.6e-06 27.2 0.0 1.9e-05 23.7 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 KFH40862.1 - 4.1e-06 25.7 0.0 9.8e-05 21.1 0.0 2.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KFH40862.1 - 0.014 15.3 1.2 0.92 9.3 0.0 2.3 2 0 0 2 2 2 0 short chain dehydrogenase Epimerase_Csub PF13950.1 KFH40862.1 - 0.083 12.8 0.2 0.29 11.1 0.0 2.0 3 0 0 3 3 3 0 UDP-glucose 4-epimerase C-term subunit F-box PF00646.28 KFH40863.1 - 0.2 11.3 2.4 0.62 9.7 0.7 2.1 1 1 1 2 2 2 0 F-box domain Glycophorin_A PF01102.13 KFH40864.1 - 0.024 14.3 0.4 0.027 14.2 0.3 1.2 1 0 0 1 1 1 0 Glycophorin A HpcH_HpaI PF03328.9 KFH40865.1 - 3.3e-29 101.3 0.0 4.4e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Orthopox_F6 PF06601.7 KFH40865.1 - 0.14 12.1 0.2 0.28 11.1 0.2 1.5 1 0 0 1 1 1 0 Orthopoxvirus F6 protein Dicty_REP PF05086.7 KFH40866.1 - 0.17 9.5 0.3 0.21 9.3 0.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein BRO1 PF03097.13 KFH40867.1 - 1.5e-110 369.4 0.0 2.7e-110 368.6 0.0 1.4 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 KFH40867.1 - 9.2e-75 251.3 8.6 2.1e-74 250.1 5.9 1.6 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DHC_N1 PF08385.7 KFH40867.1 - 0.055 11.8 1.2 5.9 5.1 0.0 2.2 2 0 0 2 2 2 0 Dynein heavy chain, N-terminal region 1 F-box PF00646.28 KFH40868.1 - 1.3e-06 27.8 1.2 2.3e-06 27.0 0.1 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KFH40868.1 - 2.5e-05 23.8 0.1 7.2e-05 22.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like Inositol_P PF00459.20 KFH40869.1 - 2.7e-34 118.6 0.0 7.6e-34 117.2 0.0 1.6 1 1 0 1 1 1 1 Inositol monophosphatase family GST_C_3 PF14497.1 KFH40871.1 - 9.8e-08 32.3 0.0 1.5e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFH40871.1 - 0.00018 21.4 0.0 0.00031 20.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KFH40871.1 - 0.00021 21.4 0.0 0.0051 16.9 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFH40871.1 - 0.00039 20.2 0.0 0.00087 19.1 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KFH40871.1 - 0.13 12.5 0.0 0.38 11.0 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain RhoGAP PF00620.22 KFH40872.1 - 2.6e-36 124.5 0.0 7e-36 123.1 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 KFH40872.1 - 5.7e-30 103.1 38.4 4.9e-12 45.7 4.7 4.9 5 0 0 5 5 5 4 LIM domain zf-UBR PF02207.15 KFH40873.1 - 3.3e-17 61.9 16.6 3.3e-17 61.9 11.5 2.2 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 KFH40873.1 - 4.7e-07 29.4 0.0 1.4e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Nefa_Nip30_N PF10187.4 KFH40874.1 - 1.7e-24 85.9 21.1 3.8e-24 84.7 14.6 1.6 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Med3 PF11593.3 KFH40874.1 - 0.017 14.4 1.4 0.019 14.2 1.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CAF-1_p150 PF11600.3 KFH40874.1 - 0.062 12.6 27.5 0.12 11.7 19.0 1.4 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Peptidase_S64 PF08192.6 KFH40874.1 - 0.063 11.6 3.4 0.078 11.3 1.8 1.5 2 0 0 2 2 2 0 Peptidase family S64 ASFV_J13L PF05568.6 KFH40874.1 - 0.21 11.1 2.5 0.34 10.4 1.7 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein HAUS6_N PF14661.1 KFH40874.1 - 0.38 10.0 11.9 0.55 9.5 8.3 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Macoilin PF09726.4 KFH40874.1 - 0.69 8.1 10.2 1.1 7.4 7.1 1.3 1 0 0 1 1 1 0 Transmembrane protein RAP1 PF07218.6 KFH40874.1 - 0.73 7.8 8.3 0.95 7.4 5.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) IncA PF04156.9 KFH40874.1 - 0.99 8.9 6.8 1.4 8.4 4.7 1.2 1 0 0 1 1 1 0 IncA protein Hex_IIIa PF02455.11 KFH40874.1 - 6.1 5.4 9.4 8 5.0 6.5 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) AAA PF00004.24 KFH40875.1 - 4.8e-43 146.5 0.0 8.8e-43 145.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFH40875.1 - 1e-07 32.1 0.0 6.4e-06 26.2 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 KFH40875.1 - 1.4e-06 28.0 0.1 3.7e-05 23.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KFH40875.1 - 2.8e-06 27.4 0.0 0.001 19.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 KFH40875.1 - 3.2e-06 27.1 0.0 7.7e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KFH40875.1 - 7.3e-06 25.2 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 KFH40875.1 - 0.00018 20.5 0.0 0.00058 18.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 KFH40875.1 - 0.00032 20.3 0.0 0.00075 19.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 KFH40875.1 - 0.00061 20.5 0.7 0.002 18.9 0.1 2.3 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 KFH40875.1 - 0.001 18.9 0.0 0.0027 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFH40875.1 - 0.0014 18.5 0.0 0.0063 16.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 KFH40875.1 - 0.0017 17.1 0.0 0.0031 16.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 KFH40875.1 - 0.0018 18.5 0.3 0.0081 16.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KFH40875.1 - 0.0023 17.3 0.0 0.0054 16.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 KFH40875.1 - 0.003 16.7 0.0 0.0062 15.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KFH40875.1 - 0.0049 17.0 0.0 0.0096 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 KFH40875.1 - 0.005 15.9 0.0 0.012 14.7 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin DUF4200 PF13863.1 KFH40875.1 - 0.0052 16.7 2.0 0.014 15.3 1.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) AAA_11 PF13086.1 KFH40875.1 - 0.0057 16.2 0.4 0.25 10.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 KFH40875.1 - 0.0077 15.7 0.0 0.025 14.0 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 KFH40875.1 - 0.0095 15.3 0.1 0.047 13.0 0.1 2.0 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.6 KFH40875.1 - 0.0097 15.5 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 KFH40875.1 - 0.017 14.7 0.1 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 KFH40875.1 - 0.022 14.7 0.0 0.064 13.2 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 KFH40875.1 - 0.024 14.5 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 KFH40875.1 - 0.024 14.4 0.0 0.062 13.1 0.0 1.7 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit PhoH PF02562.11 KFH40875.1 - 0.025 13.7 0.0 0.056 12.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Arch_ATPase PF01637.13 KFH40875.1 - 0.03 14.0 0.2 0.14 11.8 0.0 2.1 2 1 0 2 2 1 0 Archaeal ATPase KaiC PF06745.8 KFH40875.1 - 0.033 13.3 0.5 0.11 11.5 0.0 2.1 3 0 0 3 3 3 0 KaiC NACHT PF05729.7 KFH40875.1 - 0.041 13.5 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.1 KFH40875.1 - 0.042 14.1 2.8 3.6 7.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain UPF0079 PF02367.12 KFH40875.1 - 0.044 13.4 0.0 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 KFH40875.1 - 0.082 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 KFH40875.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 HMG_box_2 PF09011.5 KFH40876.1 - 2.8e-09 37.2 9.2 7.2e-06 26.2 3.3 3.6 2 2 0 2 2 2 2 HMG-box domain HMG_box PF00505.14 KFH40876.1 - 6.6e-08 32.7 1.9 6.6e-08 32.7 1.3 4.0 4 1 1 5 5 5 2 HMG (high mobility group) box 3Beta_HSD PF01073.14 KFH40877.1 - 7.1e-68 228.3 0.0 9.2e-68 227.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KFH40877.1 - 1.3e-30 106.6 0.0 1.8e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KFH40877.1 - 3.6e-18 65.4 0.1 4.6e-18 65.1 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KFH40877.1 - 2.1e-15 57.1 0.1 3e-15 56.7 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KFH40877.1 - 4.7e-15 55.1 0.0 1.1e-12 47.4 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 KFH40877.1 - 4.5e-07 29.0 2.4 1.1e-06 27.7 0.3 2.6 3 1 0 3 3 3 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KFH40877.1 - 1.9e-06 27.9 0.4 6.9e-06 26.0 0.2 1.9 1 1 0 1 1 1 1 short chain dehydrogenase DapB_N PF01113.15 KFH40877.1 - 0.0019 18.1 0.0 0.0052 16.6 0.0 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 KFH40877.1 - 0.0031 17.1 1.1 0.039 13.6 0.8 2.3 1 1 0 1 1 1 1 KR domain UCR_UQCRX_QCR9 PF05365.7 KFH40878.1 - 3.3e-21 74.6 4.2 3.6e-21 74.5 2.9 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF2417 PF10329.4 KFH40879.1 - 1.5e-81 273.2 0.8 2.1e-81 272.7 0.5 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 KFH40879.1 - 7.7e-06 25.9 0.9 1.5e-05 25.0 0.7 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family K_trans PF02705.11 KFH40879.1 - 0.071 11.4 5.8 0.1 10.9 4.0 1.2 1 0 0 1 1 1 0 K+ potassium transporter CRC_subunit PF08624.5 KFH40880.1 - 8.8e-58 194.1 0.0 1.5e-57 193.3 0.0 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit MSA_2 PF00985.12 KFH40880.1 - 7.3 6.6 8.1 15 5.6 5.6 1.4 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family Cyclin PF08613.6 KFH40881.1 - 2.4e-12 47.5 0.0 4.2e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin Proteasome PF00227.21 KFH40882.1 - 1e-30 106.4 0.0 1.2e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Mago-bind PF09282.5 KFH40883.1 - 1.9e-14 52.9 1.7 3.7e-14 51.9 1.2 1.5 1 0 0 1 1 1 1 Mago binding NAM-associated PF14303.1 KFH40883.1 - 1.2 9.3 9.6 1.8 8.8 6.7 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DEADboxA PF12343.3 KFH40884.1 - 0.018 15.2 0.5 0.018 15.2 0.3 2.3 2 0 0 2 2 2 0 Cold shock protein DEAD box A His_Phos_2 PF00328.17 KFH40886.1 - 9.1e-22 77.8 0.0 4.7e-21 75.4 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) eIF-6 PF01912.13 KFH40887.1 - 3.3e-80 267.8 0.2 5e-80 267.2 0.1 1.2 1 0 0 1 1 1 1 eIF-6 family Methyltransf_18 PF12847.2 KFH40888.1 - 9.2e-15 55.1 0.0 3.6e-09 37.1 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 KFH40888.1 - 6.9e-12 45.2 0.0 2.9e-11 43.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFH40888.1 - 2e-07 31.0 0.0 4e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH40888.1 - 1.6e-05 25.2 0.0 9.7e-05 22.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH40888.1 - 0.00047 19.9 0.0 0.002 17.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH40888.1 - 0.0012 19.3 0.1 3.2 8.2 0.0 3.0 1 1 1 2 2 2 2 Methyltransferase domain MetW PF07021.7 KFH40888.1 - 0.0027 17.1 0.1 0.0049 16.2 0.1 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_25 PF13649.1 KFH40888.1 - 0.003 17.9 0.0 0.0074 16.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Nucleoplasmin PF03066.10 KFH40888.1 - 0.0086 15.6 1.8 0.012 15.1 1.2 1.2 1 0 0 1 1 1 1 Nucleoplasmin AdoMet_MTase PF07757.8 KFH40888.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase MTS PF05175.9 KFH40888.1 - 0.019 14.3 0.0 0.047 13.0 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain PBP1_TM PF14812.1 KFH40888.1 - 0.35 11.1 6.9 0.62 10.4 4.8 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Apc4 PF12896.2 KFH40890.1 - 5.1e-56 189.2 0.1 7.3e-56 188.8 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 DUF3993 PF13158.1 KFH40890.1 - 0.069 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3993) DUF2420 PF10336.4 KFH40891.1 - 0.0001 21.8 0.4 0.022 14.3 0.2 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2420) Ribosomal_S3_C PF00189.15 KFH40893.1 - 7.2e-17 61.3 0.1 1.5e-16 60.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 KFH40893.1 - 2.5e-12 46.1 0.1 4.5e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 KFH40893.1 - 0.055 13.7 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 RRM_6 PF14259.1 KFH40894.1 - 4e-39 132.4 0.0 1.8e-09 37.4 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFH40894.1 - 8.5e-38 127.8 0.0 5.6e-12 45.1 0.1 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH40894.1 - 3.7e-19 68.3 0.1 0.00054 19.7 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 KFH40894.1 - 2.5e-12 46.2 4.1 2.5e-12 46.2 2.8 3.8 3 1 1 4 4 4 1 Putative RRM domain RRM_3 PF08777.6 KFH40894.1 - 0.00092 19.0 0.1 0.032 14.0 0.1 2.5 2 0 0 2 2 2 1 RNA binding motif RNA_bind PF08675.6 KFH40894.1 - 0.037 14.0 0.0 0.3 11.0 0.0 2.5 3 0 0 3 3 3 0 RNA binding domain Nup35_RRM_2 PF14605.1 KFH40894.1 - 0.085 12.6 0.1 20 5.0 0.0 3.3 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif HEAT PF02985.17 KFH40895.1 - 1.2e-45 149.5 14.3 0.00096 19.0 0.0 13.2 14 0 0 14 14 14 12 HEAT repeat HEAT_2 PF13646.1 KFH40895.1 - 1.2e-30 105.5 2.4 8.7e-09 35.5 0.0 7.2 4 3 2 6 6 6 6 HEAT repeats Vac14_Fab1_bd PF12755.2 KFH40895.1 - 1.5e-11 44.4 4.0 0.018 15.4 0.1 7.5 6 2 3 9 9 8 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KFH40895.1 - 5e-11 42.7 9.7 0.21 12.1 0.1 9.7 9 2 3 12 12 12 2 HEAT-like repeat Adaptin_N PF01602.15 KFH40895.1 - 2.1e-08 32.9 5.7 0.0051 15.1 0.1 5.2 4 1 1 5 5 5 3 Adaptin N terminal region CLASP_N PF12348.3 KFH40895.1 - 3.8e-06 26.4 4.3 0.061 12.6 0.0 4.5 5 2 1 6 6 6 3 CLASP N terminal DUF2435 PF10363.4 KFH40895.1 - 0.00018 21.3 4.3 0.044 13.6 0.1 4.5 3 1 1 4 4 4 1 Protein of unknown function (DUF2435) Arm PF00514.18 KFH40895.1 - 0.0029 17.3 0.5 1.7 8.6 0.0 4.5 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Cnd3 PF12719.2 KFH40895.1 - 0.077 11.9 0.4 0.9 8.4 0.0 2.7 4 0 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain RhoGAP PF00620.22 KFH40895.1 - 0.082 12.5 0.2 0.28 10.7 0.0 2.0 3 0 0 3 3 3 0 RhoGAP domain Cnd1 PF12717.2 KFH40895.1 - 0.11 12.2 6.7 17 5.2 0.0 5.4 4 1 2 6 6 6 0 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.4 KFH40895.1 - 0.16 10.1 2.4 0.46 8.6 0.0 2.6 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit B3_4 PF03483.12 KFH40896.1 - 1.9e-24 86.0 0.1 3.1e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 KFH40896.1 - 6.9e-16 57.8 0.0 1e-12 47.7 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain Abhydrolase_6 PF12697.2 KFH40897.1 - 1.2e-07 31.9 0.9 8.2e-07 29.1 0.6 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 KFH40897.1 - 0.01 14.8 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 KFH40897.1 - 0.085 12.1 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Gtr1_RagA PF04670.7 KFH40898.1 - 1.5e-69 233.6 0.1 1.8e-69 233.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KFH40898.1 - 0.00061 20.2 0.0 0.0026 18.2 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFH40898.1 - 0.00074 18.8 0.0 0.0013 18.0 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Adap_comp_sub PF00928.16 KFH40899.1 - 2.8e-16 59.4 0.0 4.1e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KFH40899.1 - 2.4e-08 33.8 0.0 3.9e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 KFH40899.1 - 0.0012 18.1 0.0 0.0091 15.2 0.0 2.1 1 1 0 1 1 1 1 Muniscin C-terminal mu homology domain Mg_trans_NIPA PF05653.9 KFH40900.1 - 2.2e-105 351.9 13.3 2.6e-105 351.6 9.2 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KFH40900.1 - 6e-09 36.1 2.6 6e-09 36.1 1.8 3.3 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KFH40900.1 - 8.8e-05 22.5 7.0 8.8e-05 22.5 4.9 3.4 2 1 1 3 3 3 1 EamA-like transporter family DUF1282 PF06930.7 KFH40900.1 - 6.7 6.3 17.3 1 8.9 4.9 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1282) Myotub-related PF06602.9 KFH40901.1 - 8e-126 419.5 0.0 1.2e-125 418.9 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 KFH40901.1 - 0.029 14.6 0.0 0.18 12.0 0.0 2.1 2 0 0 2 2 2 0 Tyrosine phosphatase family G-alpha PF00503.15 KFH40901.1 - 0.04 12.6 0.0 0.071 11.7 0.0 1.5 1 0 0 1 1 1 0 G-protein alpha subunit Y_phosphatase PF00102.22 KFH40901.1 - 0.13 11.5 0.0 0.3 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase ADH_zinc_N_2 PF13602.1 KFH40902.1 - 2.9e-16 60.4 0.0 6e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KFH40902.1 - 4.4e-13 48.9 0.0 8.4e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFH40902.1 - 7.7e-09 35.2 0.6 1.3e-07 31.3 0.0 2.5 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain YjeF_N PF03853.10 KFH40902.1 - 0.054 13.1 0.1 0.099 12.2 0.1 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus Glu_synthase PF01645.12 KFH40902.1 - 0.12 11.2 0.4 0.16 10.8 0.3 1.1 1 0 0 1 1 1 0 Conserved region in glutamate synthase Ferric_reduct PF01794.14 KFH40905.1 - 9.5e-19 67.7 17.2 9.5e-19 67.7 11.9 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KFH40905.1 - 4.2e-11 42.6 0.0 2.7e-05 23.9 0.0 2.3 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.7 KFH40905.1 - 1.2e-07 31.8 0.0 3.9e-06 26.8 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 KFH40905.1 - 0.072 13.6 0.0 0.39 11.2 0.0 2.2 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain MerC PF03203.9 KFH40905.1 - 1.9 8.8 15.5 0.052 13.9 3.6 3.1 4 0 0 4 4 4 0 MerC mercury resistance protein Abhydrolase_6 PF12697.2 KFH40907.1 - 3.6e-29 102.2 0.0 5.4e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFH40907.1 - 2.9e-16 59.7 0.0 2.6e-14 53.3 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFH40907.1 - 5.3e-11 42.4 0.0 1e-10 41.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KFH40907.1 - 1e-06 28.4 0.0 1.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 KFH40907.1 - 0.022 14.0 0.0 0.05 12.8 0.0 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 KFH40907.1 - 0.029 13.2 0.0 0.044 12.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.6 KFH40907.1 - 0.038 12.7 0.0 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_2 PF02230.11 KFH40907.1 - 0.099 12.0 0.0 0.48 9.8 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Sugar_tr PF00083.19 KFH40908.1 - 3.6e-115 385.1 26.8 4.2e-115 384.9 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH40908.1 - 3.2e-19 68.8 40.7 3.2e-16 59.0 19.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFH40908.1 - 7.2e-07 27.9 3.5 7.2e-07 27.9 2.4 3.7 3 1 1 4 4 4 2 MFS/sugar transport protein MFS_1_like PF12832.2 KFH40908.1 - 0.38 10.5 9.5 2.1 8.1 0.1 3.4 3 0 0 3 3 3 0 MFS_1 like family Rtf2 PF04641.7 KFH40909.1 - 1.2e-53 181.9 0.6 1.7e-53 181.4 0.4 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_UBOX PF13445.1 KFH40909.1 - 0.00016 21.3 0.2 0.00041 20.0 0.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 KFH40909.1 - 0.00073 19.3 0.2 0.0045 16.7 0.2 2.0 1 1 1 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KFH40909.1 - 0.0016 18.1 0.1 0.0026 17.4 0.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFH40909.1 - 0.0023 17.5 0.1 0.0037 16.9 0.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFH40909.1 - 0.024 14.2 0.2 0.046 13.3 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFH40909.1 - 0.04 13.9 0.4 0.1 12.6 0.3 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 KFH40909.1 - 0.043 13.3 0.2 0.098 12.1 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit YhfH PF14149.1 KFH40909.1 - 0.073 12.8 0.2 0.2 11.4 0.2 1.7 1 0 0 1 1 1 0 YhfH-like protein UPF0547 PF10571.4 KFH40909.1 - 0.085 12.5 2.2 0.96 9.2 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-RING_4 PF14570.1 KFH40909.1 - 0.1 12.2 0.2 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn-ribbon_8 PF09723.5 KFH40909.1 - 0.15 12.0 1.1 0.38 10.7 0.8 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Vfa1 PF08432.5 KFH40909.1 - 0.23 11.4 11.4 0.33 10.9 7.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FAM176 PF14851.1 KFH40909.1 - 0.25 11.0 5.2 0.42 10.2 3.6 1.3 1 0 0 1 1 1 0 FAM176 family PRTP PF01366.13 KFH40909.1 - 0.29 9.0 3.2 0.37 8.7 2.2 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein FYDLN_acid PF09538.5 KFH40909.1 - 0.71 10.4 11.0 1.5 9.4 7.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) FancD2 PF14631.1 KFH40909.1 - 2 5.4 5.3 2.5 5.0 3.7 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease U79_P34 PF03064.11 KFH40909.1 - 2.1 7.7 12.9 3 7.2 8.9 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Peptidase_S49_N PF08496.5 KFH40909.1 - 3.1 7.5 6.7 5.5 6.7 4.7 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Zn_clus PF00172.13 KFH40910.1 - 5.5e-08 32.5 8.7 9e-08 31.8 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2335 PF10097.4 KFH40911.1 - 0.081 12.5 13.4 12 5.5 0.1 4.6 5 0 0 5 5 5 0 Predicted membrane protein (DUF2335) Hist_rich_Ca-bd PF10529.4 KFH40912.1 - 2.6 8.1 6.0 0.22 11.5 1.0 1.7 2 0 0 2 2 2 0 Histidine-rich Calcium-binding repeat region ketoacyl-synt PF00109.21 KFH40913.1 - 2.1e-65 220.7 5.4 1.6e-55 188.3 1.2 2.9 3 0 0 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KFH40913.1 - 1.2e-59 200.9 0.1 2.9e-59 199.7 0.1 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 KFH40913.1 - 1e-47 163.0 0.0 2e-47 162.0 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KFH40913.1 - 2.7e-44 151.5 0.0 4.6e-44 150.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KFH40913.1 - 2.3e-42 144.7 0.1 2.3e-42 144.7 0.1 2.3 2 0 0 2 2 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KFH40913.1 - 9.5e-40 135.1 0.1 2.8e-39 133.6 0.0 1.9 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KFH40913.1 - 1.4e-18 67.2 0.0 3.4e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KFH40913.1 - 9.3e-16 57.5 2.4 6.3e-15 54.8 0.5 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFH40913.1 - 3.8e-13 50.4 0.4 6.6e-12 46.4 0.1 3.4 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KFH40913.1 - 2.3e-09 37.1 0.0 6.7e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH40913.1 - 1.6e-08 35.1 0.0 4.1e-07 30.5 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH40913.1 - 1.4e-07 31.2 0.0 3e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH40913.1 - 4e-07 30.4 0.0 1.2e-06 28.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KFH40913.1 - 6.8e-07 29.4 0.1 3.6e-06 27.1 0.1 2.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.1 KFH40913.1 - 4.2e-05 23.8 0.0 0.00018 21.7 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 KFH40913.1 - 7.1e-05 21.9 0.7 0.00023 20.2 0.1 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 KFH40913.1 - 0.00012 21.2 0.0 0.00026 20.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KFH40913.1 - 0.0076 16.2 0.0 0.05 13.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain NodS PF05401.6 KFH40913.1 - 0.096 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) Vpu PF00558.14 KFH40913.1 - 0.24 11.0 0.0 0.53 9.8 0.0 1.5 1 0 0 1 1 1 0 Vpu protein NAS PF03059.11 KFH40913.1 - 0.33 10.0 0.0 0.71 8.9 0.0 1.4 1 0 0 1 1 1 0 Nicotianamine synthase protein DNA_III_psi PF03603.8 KFH40913.1 - 0.34 10.7 3.4 0.85 9.4 1.5 2.2 2 0 0 2 2 2 0 DNA polymerase III psi subunit FAT PF02259.18 KFH40914.1 - 2e-125 418.4 9.9 2e-125 418.4 6.8 2.3 2 1 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 KFH40914.1 - 3.6e-63 213.1 0.4 7.5e-63 212.1 0.2 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 KFH40914.1 - 7.6e-55 185.2 1.4 3.5e-53 179.7 0.3 3.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 KFH40914.1 - 1.4e-44 150.2 2.6 2.7e-44 149.3 0.1 3.0 2 0 0 2 2 2 1 Rapamycin binding domain HEAT_2 PF13646.1 KFH40914.1 - 9.7e-17 61.0 8.9 0.003 17.7 0.1 9.1 6 1 5 11 11 10 6 HEAT repeats FATC PF02260.15 KFH40914.1 - 4.3e-14 51.6 0.1 1.1e-13 50.3 0.1 1.7 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 KFH40914.1 - 2.8e-13 48.7 16.4 0.11 12.6 0.0 11.3 12 0 0 12 12 12 4 HEAT repeat HEAT_EZ PF13513.1 KFH40914.1 - 5.5e-09 36.2 10.0 0.004 17.5 0.0 9.8 9 2 3 12 12 10 3 HEAT-like repeat Adaptin_N PF01602.15 KFH40914.1 - 2.6e-08 32.6 6.9 0.0037 15.6 0.0 5.2 5 1 0 5 5 5 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 KFH40914.1 - 8.1e-07 29.3 0.4 5.6 7.4 0.0 6.9 6 1 1 7 7 7 1 Vacuolar 14 Fab1-binding region Sec7_N PF12783.2 KFH40914.1 - 0.0034 16.8 4.6 9.2 5.6 0.7 4.8 4 1 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DNA_primase_S PF01896.14 KFH40915.1 - 1.2e-55 187.2 0.1 1.9e-55 186.6 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit DUF4183 PF13799.1 KFH40915.1 - 0.18 11.6 0.0 1 9.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4183) Epimerase PF01370.16 KFH40916.1 - 3e-21 75.9 0.0 3.9e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFH40916.1 - 7.2e-14 51.1 0.0 9.4e-14 50.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KFH40916.1 - 5.8e-10 38.5 0.1 1.3e-07 30.7 0.1 2.2 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 KFH40916.1 - 7.7e-09 34.8 0.0 1.1e-07 31.0 0.0 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KFH40916.1 - 1.7e-06 28.2 0.0 2.3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KFH40916.1 - 6.4e-05 22.9 0.2 0.0018 18.2 0.2 2.2 1 1 0 1 1 1 1 short chain dehydrogenase Ldh_1_N PF00056.18 KFH40916.1 - 0.00018 21.3 0.0 0.00023 20.9 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain KR PF08659.5 KFH40916.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.6 1 1 0 1 1 1 0 KR domain 2-Hacid_dh_C PF02826.14 KFH40917.1 - 1.8e-50 170.5 0.0 2.4e-50 170.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFH40917.1 - 1.3e-16 60.2 0.0 1.9e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KFH40917.1 - 3e-05 23.8 0.1 0.0001 22.2 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 KFH40917.1 - 0.023 14.0 0.1 0.052 12.9 0.0 1.6 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Zip PF02535.17 KFH40918.1 - 9.4e-25 87.2 49.7 6.9e-13 48.2 2.9 4.1 3 1 1 4 4 4 3 ZIP Zinc transporter DUF2410 PF10307.4 KFH40919.1 - 4.5e-80 267.6 0.0 8e-80 266.8 0.0 1.4 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) Carb_anhydrase PF00194.16 KFH40920.1 - 3.8e-19 68.6 0.0 3.2e-09 36.1 0.0 2.3 2 1 0 2 2 2 2 Eukaryotic-type carbonic anhydrase tRNA_m1G_MT PF01746.16 KFH40921.1 - 1.6e-31 109.3 0.0 1.1e-25 90.3 0.0 2.3 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase HSF_DNA-bind PF00447.12 KFH40922.1 - 3.7e-29 100.9 0.1 7.4e-29 99.9 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 KFH40922.1 - 6.1e-23 80.9 0.0 1.3e-22 79.9 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain DUF972 PF06156.8 KFH40922.1 - 0.052 13.8 0.7 0.052 13.8 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) MutS_V PF00488.16 KFH40924.1 - 3.3e-98 327.7 0.0 4.7e-98 327.2 0.0 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KFH40924.1 - 2.3e-40 138.5 0.3 5.1e-40 137.4 0.2 1.6 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 KFH40924.1 - 3e-22 79.1 1.5 7.6e-22 77.8 0.0 2.5 3 0 0 3 3 3 1 MutS domain II MutS_I PF01624.15 KFH40924.1 - 2.7e-19 69.2 0.0 1.3e-18 67.0 0.0 2.1 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 KFH40924.1 - 2.9e-12 46.5 1.8 8.6e-12 45.0 0.2 2.7 3 0 0 3 3 3 1 MutS family domain IV GAD PF02938.9 KFH40924.1 - 0.067 13.3 0.1 0.29 11.3 0.1 2.1 1 0 0 1 1 1 0 GAD domain FMN_dh PF01070.13 KFH40925.1 - 4.1e-118 394.2 0.0 5.3e-118 393.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KFH40925.1 - 2.8e-19 68.6 0.0 5.2e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NMO PF03060.10 KFH40925.1 - 2.6e-07 30.1 0.0 2.3e-05 23.7 0.0 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase Glu_synthase PF01645.12 KFH40925.1 - 5.2e-05 22.3 0.1 8.2e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KFH40925.1 - 0.00034 19.6 0.2 0.0014 17.5 0.1 1.9 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 KFH40925.1 - 0.017 14.2 0.0 2.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Hexapep PF00132.19 KFH40926.1 - 7.4e-09 34.7 9.7 8.2e-06 25.1 2.3 4.1 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) W2 PF02020.13 KFH40926.1 - 4.9e-08 32.8 0.0 1.5e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon NTP_transferase PF00483.18 KFH40926.1 - 0.0018 17.6 0.0 0.0029 16.9 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.1 KFH40926.1 - 0.0037 16.7 8.5 0.053 13.0 1.3 3.4 2 1 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.2 KFH40926.1 - 0.0041 17.2 0.0 0.011 15.8 0.0 1.8 2 0 0 2 2 2 1 MobA-like NTP transferase domain MFS_1 PF07690.11 KFH40927.1 - 3.4e-30 104.9 36.8 3.4e-30 104.9 25.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4381 PF14316.1 KFH40927.1 - 1.4 8.9 5.5 9.7 6.2 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Tim17 PF02466.14 KFH40928.1 - 1.1e-07 31.9 4.7 4.7e-07 29.9 3.3 1.8 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_OmpA PF13436.1 KFH40928.1 - 0.0016 18.0 0.0 1.9 8.2 0.0 2.2 2 0 0 2 2 2 2 Glycine-zipper containing OmpA-like membrane domain Bacteriocin_IIc PF10439.4 KFH40928.1 - 0.026 14.6 4.2 0.49 10.5 0.6 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide DUF543 PF04418.7 KFH40928.1 - 0.29 11.1 2.8 18 5.3 2.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Gly-zipper_YMGG PF13441.1 KFH40928.1 - 4.2 6.9 11.3 4.3 6.9 0.1 2.6 2 1 0 2 2 2 0 YMGG-like Gly-zipper Zn_clus PF00172.13 KFH40929.1 - 1.5e-05 24.7 9.0 2.2e-05 24.2 6.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.23 KFH40930.1 - 7.8e-80 268.2 0.1 1.2e-79 267.6 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 KFH40930.1 - 1.6e-74 250.6 0.2 3.9e-74 249.3 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KFH40930.1 - 1.4e-52 178.9 0.4 1.4e-52 178.9 0.3 2.0 2 0 0 2 2 2 1 Acyl transferase domain KR PF08659.5 KFH40930.1 - 9.9e-48 162.1 0.0 8.2e-43 146.1 0.0 3.2 3 0 0 3 3 2 2 KR domain PS-DH PF14765.1 KFH40930.1 - 6.9e-46 156.7 0.4 1.4e-45 155.7 0.3 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KFH40930.1 - 5.4e-43 146.7 0.1 2e-36 125.4 0.0 3.9 3 0 0 3 3 3 2 short chain dehydrogenase Condensation PF00668.15 KFH40930.1 - 2.6e-33 115.1 0.7 4.2e-33 114.4 0.5 1.3 1 0 0 1 1 1 1 Condensation domain Ketoacyl-synt_C PF02801.17 KFH40930.1 - 5.9e-32 110.0 0.0 2.3e-31 108.1 0.0 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 KFH40930.1 - 3.1e-23 81.9 0.0 2.8e-22 78.8 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.7 KFH40930.1 - 2.4e-16 60.0 0.0 7.6e-16 58.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KFH40930.1 - 6.2e-15 55.2 0.2 2.1e-07 31.1 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site NAD_binding_10 PF13460.1 KFH40930.1 - 5.3e-12 46.1 4.1 1.2e-11 44.9 0.0 3.5 4 0 0 4 4 4 1 NADH(P)-binding Methyltransf_23 PF13489.1 KFH40930.1 - 7.4e-12 45.2 0.0 2.3e-11 43.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 KFH40930.1 - 1.3e-10 41.1 0.0 3.5e-09 36.4 0.0 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family HxxPF_rpt PF13745.1 KFH40930.1 - 1.4e-10 41.2 0.0 3.7e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 HxxPF-repeated domain Methyltransf_11 PF08241.7 KFH40930.1 - 2.1e-10 40.9 0.0 7.9e-10 39.0 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH40930.1 - 3.1e-08 34.1 0.0 3.8e-07 30.6 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH40930.1 - 6e-08 32.4 0.0 1.8e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFH40930.1 - 1.4e-05 24.3 0.0 2.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Semialdhyde_dh PF01118.19 KFH40930.1 - 6.4e-05 23.2 0.0 0.0079 16.4 0.0 3.4 3 0 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 KFH40930.1 - 7.6e-05 21.7 0.0 0.00019 20.3 0.0 1.7 1 0 0 1 1 1 1 RmlD substrate binding domain Thiolase_N PF00108.18 KFH40930.1 - 0.00016 20.7 0.0 0.00032 19.7 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain DapB_N PF01113.15 KFH40930.1 - 0.01 15.7 0.0 0.39 10.6 0.0 3.2 4 0 0 4 4 2 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.14 KFH40930.1 - 0.014 14.1 0.0 0.17 10.5 0.0 2.4 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family MTS PF05175.9 KFH40930.1 - 0.05 12.9 0.0 0.16 11.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.15 KFH40930.1 - 0.21 10.5 0.0 0.41 9.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Polysacc_synt_2 PF02719.10 KFH40930.1 - 0.28 10.0 0.0 1.1 8.1 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DHC_N1 PF08385.7 KFH40930.1 - 4.4 5.5 1.4 7 4.8 1.0 1.2 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 Aminotran_1_2 PF00155.16 KFH40931.1 - 2.1e-48 165.1 0.0 2.5e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II BtpA PF03437.10 KFH40932.1 - 0.14 11.3 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 BtpA family WD40 PF00400.27 KFH40933.1 - 1.7e-149 481.0 49.8 1e-15 56.8 0.2 12.3 12 0 0 12 12 12 11 WD domain, G-beta repeat eIF2A PF08662.6 KFH40933.1 - 4.9e-18 65.5 3.0 0.0047 16.6 0.1 5.8 2 1 4 6 6 6 5 Eukaryotic translation initiation factor eIF2A NACHT PF05729.7 KFH40933.1 - 4e-17 62.3 0.0 9.2e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Nup160 PF11715.3 KFH40933.1 - 6.1e-13 47.7 7.1 0.074 11.1 0.1 6.8 1 1 4 6 6 6 4 Nucleoporin Nup120/160 PD40 PF07676.7 KFH40933.1 - 7.3e-12 44.6 9.3 13 5.5 0.0 10.4 10 0 0 10 10 10 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 KFH40933.1 - 4.2e-08 31.8 0.8 0.031 12.5 0.0 4.7 2 1 3 5 5 5 3 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 KFH40933.1 - 4.1e-07 29.1 8.8 0.11 11.2 0.3 6.7 1 1 4 5 5 5 3 Nup133 N terminal like AAA_22 PF13401.1 KFH40933.1 - 5.4e-05 23.3 0.6 0.43 10.7 0.0 3.5 3 0 0 3 3 3 2 AAA domain Proteasome_A_N PF10584.4 KFH40933.1 - 0.00079 18.6 17.5 40 3.6 0.0 9.3 10 0 0 10 10 10 0 Proteasome subunit A N-terminal signature Filo_glycop PF01611.11 KFH40933.1 - 0.002 16.9 9.5 1.3 7.7 0.1 4.8 4 1 0 5 5 5 2 Filovirus glycoprotein AAA_16 PF13191.1 KFH40933.1 - 0.01 15.8 7.0 0.011 15.7 1.2 3.1 2 1 0 2 2 2 0 AAA ATPase domain DUF2075 PF09848.4 KFH40933.1 - 0.017 14.1 0.0 0.035 13.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) GTP_EFTU PF00009.22 KFH40933.1 - 0.02 14.3 0.4 20 4.5 0.0 4.8 4 1 1 5 5 5 0 Elongation factor Tu GTP binding domain IKI3 PF04762.7 KFH40933.1 - 0.021 12.6 0.5 29 2.2 0.0 4.2 2 2 1 4 4 4 0 IKI3 family YdjO PF14169.1 KFH40933.1 - 0.036 13.5 38.3 5.8 6.4 0.1 9.0 10 0 0 10 10 8 0 Cold-inducible protein YdjO Metallothi_Euk2 PF12809.2 KFH40933.1 - 0.036 14.4 14.0 82 3.6 0.0 7.4 8 0 0 8 8 8 0 Eukaryotic metallothionein DEAD PF00270.24 KFH40933.1 - 0.039 13.4 0.0 0.23 10.9 0.0 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase DUF1936 PF09151.5 KFH40933.1 - 0.22 11.0 2.6 1.5e+02 1.9 0.0 5.0 5 0 0 5 5 5 0 Domain of unknown function (DUF1936) Amidohydro_4 PF13147.1 KFH40934.1 - 1.3e-09 38.5 5.0 1.3e-09 38.5 3.5 3.6 2 2 0 2 2 2 1 Amidohydrolase Amidohydro_5 PF13594.1 KFH40934.1 - 3.8e-09 36.2 0.3 2.6e-07 30.3 0.0 2.8 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 KFH40934.1 - 3e-07 30.4 0.2 1.1e-05 25.3 0.0 2.6 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.6 KFH40934.1 - 0.00014 21.1 0.1 0.00014 21.1 0.1 2.2 3 1 0 3 3 3 1 Amidohydrolase family BSP_II PF05432.6 KFH40934.1 - 0.81 8.9 14.8 0.13 11.4 1.6 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Nucleoplasmin PF03066.10 KFH40934.1 - 1.9 7.9 8.1 7.5 6.0 1.0 2.3 2 0 0 2 2 2 0 Nucleoplasmin Spt5_N PF11942.3 KFH40934.1 - 7 7.3 21.9 5.7 7.6 2.8 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal LigB PF02900.13 KFH40936.1 - 1.9e-46 158.2 0.1 2.3e-46 157.9 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Glyco_hydro_18 PF00704.23 KFH40939.1 - 2.7e-83 280.2 8.0 3.3e-83 279.9 5.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Tyrosinase PF00264.15 KFH40940.1 - 4.3e-44 151.3 1.6 5.9e-44 150.8 1.1 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase KR PF08659.5 KFH40941.1 - 1.9e-07 30.9 0.0 2e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KFH40941.1 - 9.8e-07 28.8 0.1 1.1e-06 28.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Aldo_ket_red PF00248.16 KFH40942.1 - 2e-34 118.7 0.0 2.4e-34 118.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PLAC8 PF04749.12 KFH40943.1 - 1.2e-25 90.1 14.7 1.5e-25 89.7 10.2 1.1 1 0 0 1 1 1 1 PLAC8 family NPP1 PF05630.6 KFH40944.1 - 4.6e-76 255.1 4.6 5.5e-76 254.8 3.2 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Glyco_hydro_2_N PF02837.13 KFH40945.1 - 7.8e-26 90.6 0.1 7.8e-26 90.6 0.1 2.4 3 0 0 3 3 3 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KFH40945.1 - 5.2e-15 55.1 0.1 8.1e-15 54.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 KFH40945.1 - 1.2e-10 41.8 0.0 7.9e-10 39.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 FlgD_ig PF13860.1 KFH40945.1 - 0.017 14.8 1.7 0.037 13.7 1.2 1.5 1 0 0 1 1 1 0 FlgD Ig-like domain EMP24_GP25L PF01105.19 KFH40945.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Big_3_4 PF13754.1 KFH40945.1 - 2.2 8.6 11.6 0.23 11.8 3.2 2.9 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) SDH_alpha PF03313.10 KFH40947.1 - 2.4e-91 305.7 0.5 3.4e-91 305.1 0.3 1.2 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.10 KFH40947.1 - 9.8e-51 171.9 0.0 1.9e-50 171.0 0.0 1.4 1 0 0 1 1 1 1 Serine dehydratase beta chain Peptidase_S8 PF00082.17 KFH40949.1 - 1.2e-45 155.8 13.8 2e-45 155.1 9.6 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KFH40949.1 - 1e-16 61.2 1.2 1.8e-16 60.4 0.8 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Peptidase_S8 PF00082.17 KFH40951.1 - 1.7e-47 161.9 11.8 2.3e-47 161.4 8.2 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KFH40951.1 - 4.7e-12 46.2 0.1 1.6e-11 44.5 0.1 1.9 1 1 0 1 1 1 1 Peptidase inhibitor I9 Galactosyl_T PF01762.16 KFH40953.1 - 1.5e-13 50.8 1.7 3.4e-12 46.3 1.2 2.1 1 1 0 1 1 1 1 Galactosyltransferase Phospholip_A2_3 PF09056.6 KFH40954.1 - 6.8e-45 151.8 0.7 9.5e-45 151.3 0.5 1.2 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 Arrestin_C PF02752.17 KFH40955.1 - 1.3e-18 67.3 0.0 1.7e-17 63.8 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KFH40955.1 - 1.7e-15 57.1 0.0 3.4e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 KFH40955.1 - 0.013 14.9 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 Arrestin_N terminal like Nup96 PF12110.3 KFH40957.1 - 1.8e-90 302.9 0.3 2.5e-90 302.5 0.2 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 KFH40957.1 - 1.9e-51 173.5 0.0 3.3e-51 172.8 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 KFH40957.1 - 2e-39 134.3 423.3 1.9e-14 53.8 30.8 11.7 4 2 9 13 13 13 9 Nucleoporin FG repeat region Ribosomal_L7Ae PF01248.21 KFH40958.1 - 8.4e-22 76.5 1.0 1.6e-21 75.5 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PurS PF02700.9 KFH40960.1 - 0.18 11.7 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine (FGAM) synthase MOZ_SAS PF01853.13 KFH40961.1 - 9.2e-80 266.3 0.0 1.3e-79 265.8 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Miro PF08477.8 KFH40962.1 - 9.1e-34 116.5 0.0 5.5e-17 62.3 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 KFH40962.1 - 1.9e-31 107.6 0.0 4.1e-31 106.5 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 KFH40962.1 - 2.4e-31 106.8 0.1 7.3e-31 105.2 0.0 1.8 2 0 0 2 2 2 1 EF hand associated Ras PF00071.17 KFH40962.1 - 9e-20 70.6 0.0 7.6e-13 48.1 0.0 2.2 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 KFH40962.1 - 2.4e-07 30.6 0.0 0.027 14.4 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_7 PF13499.1 KFH40962.1 - 6e-07 29.4 1.8 0.00025 21.1 0.1 2.8 3 0 0 3 3 2 1 EF-hand domain pair Dynamin_N PF00350.18 KFH40962.1 - 7.2e-07 29.1 0.0 0.0033 17.2 0.1 2.9 2 1 1 3 3 3 2 Dynamin family EF-hand_1 PF00036.27 KFH40962.1 - 1.1e-06 27.4 2.9 0.0017 17.5 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KFH40962.1 - 8.6e-06 25.2 3.7 0.0073 16.1 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain AAA_16 PF13191.1 KFH40962.1 - 1.6e-05 25.0 0.0 0.011 15.7 0.0 2.7 3 0 0 3 3 2 1 AAA ATPase domain AAA_29 PF13555.1 KFH40962.1 - 0.00011 21.6 0.0 0.0069 15.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.1 KFH40962.1 - 0.0014 18.6 0.0 1.3 8.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KFH40962.1 - 0.0035 17.4 0.0 0.22 11.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain EF-hand_5 PF13202.1 KFH40962.1 - 0.0064 15.7 6.7 0.32 10.4 0.1 2.7 2 0 0 2 2 2 2 EF hand GTP_EFTU PF00009.22 KFH40962.1 - 0.0078 15.6 0.0 13 5.2 0.0 3.2 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_21 PF13304.1 KFH40962.1 - 0.0083 16.1 0.1 1.3 8.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.1 KFH40962.1 - 0.0092 15.5 0.0 2.4 7.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 KFH40962.1 - 0.017 15.3 0.0 0.46 10.7 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_25 PF13481.1 KFH40962.1 - 0.04 13.3 0.0 1.7 7.9 0.0 2.6 3 0 0 3 3 2 0 AAA domain EF-hand_10 PF14788.1 KFH40962.1 - 0.051 13.2 0.2 0.15 11.7 0.1 1.7 1 0 0 1 1 1 0 EF hand Viral_helicase1 PF01443.13 KFH40962.1 - 0.082 12.4 0.0 0.26 10.7 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF258 PF03193.11 KFH40962.1 - 0.092 11.9 0.0 5.3 6.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 KFH40962.1 - 0.098 12.5 0.0 2.5 7.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KFH40962.1 - 0.15 12.2 0.0 15 5.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase MobB PF03205.9 KFH40962.1 - 0.16 11.6 0.0 0.94 9.1 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 KFH40962.1 - 0.18 12.0 0.0 0.78 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain SET PF00856.23 KFH40963.1 - 4.3e-06 27.1 0.1 0.074 13.3 0.0 3.1 3 0 0 3 3 3 3 SET domain WD40 PF00400.27 KFH40964.1 - 4.3e-22 77.1 4.6 1.5e-07 31.0 0.1 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat eIF2A PF08662.6 KFH40964.1 - 8e-05 22.4 0.0 0.00043 20.0 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 KFH40964.1 - 0.00045 18.1 0.0 0.001 17.0 0.0 1.4 1 1 1 2 2 2 1 IKI3 family PD40 PF07676.7 KFH40964.1 - 0.028 14.0 0.0 11 5.8 0.0 3.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat ENTH PF01417.15 KFH40965.1 - 1.3e-49 167.1 0.0 2.1e-49 166.5 0.0 1.3 1 0 0 1 1 1 1 ENTH domain DUF4264 PF14084.1 KFH40965.1 - 0.00076 18.7 0.1 0.0013 18.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4264) ANTH PF07651.11 KFH40965.1 - 0.0078 14.9 0.0 0.012 14.3 0.0 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.14 KFH40965.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 VHS domain DUF1510 PF07423.6 KFH40965.1 - 0.23 10.8 0.0 0.23 10.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) UIM PF02809.15 KFH40965.1 - 0.34 10.5 4.1 0.98 9.1 0.1 2.9 2 0 0 2 2 2 0 Ubiquitin interaction motif EF-hand_7 PF13499.1 KFH40966.1 - 9.8e-21 73.6 10.8 4.3e-11 42.7 0.5 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KFH40966.1 - 1.2e-14 53.5 10.8 2.2e-12 46.4 2.5 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 KFH40966.1 - 2.3e-14 51.5 7.5 5.4e-05 22.1 0.2 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 KFH40966.1 - 3e-12 45.3 3.8 8.2e-05 22.1 0.1 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.1 KFH40966.1 - 2.7e-08 32.8 1.2 0.0003 19.9 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 KFH40966.1 - 0.00011 22.0 0.4 0.00079 19.2 0.3 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_like PF09279.6 KFH40966.1 - 0.24 11.4 1.5 0.47 10.5 0.5 1.8 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like DUF4546 PF15079.1 KFH40966.1 - 0.54 9.3 4.0 1.3 8.1 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4546) ATP_bind_3 PF01171.15 KFH40967.1 - 3.8e-18 65.6 0.0 5.8e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 KFH40967.1 - 9.5e-05 22.6 0.0 0.00026 21.3 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) tRNA_Me_trans PF03054.11 KFH40967.1 - 0.039 12.5 0.0 0.062 11.8 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase RecR PF02132.10 KFH40967.1 - 0.041 13.3 0.5 0.041 13.3 0.3 2.6 3 0 0 3 3 3 0 RecR protein NTF2 PF02136.15 KFH40968.1 - 4.3e-25 88.3 1.1 4.1e-23 82.0 0.7 2.0 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Pox_MCEL PF03291.11 KFH40969.1 - 4.6e-66 222.9 0.0 6.7e-47 159.9 0.0 2.2 2 0 0 2 2 2 2 mRNA capping enzyme Methyltransf_12 PF08242.7 KFH40969.1 - 1.2e-09 38.5 0.0 0.0016 18.8 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 KFH40969.1 - 1.1e-07 32.1 0.0 8.5e-07 29.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH40969.1 - 3.2e-07 30.1 0.0 5.9e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH40969.1 - 3.8e-07 30.6 0.0 8.4e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH40969.1 - 9.1e-06 25.3 0.0 0.00035 20.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFH40969.1 - 2.3e-05 24.6 0.0 4.4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Raftlin PF15250.1 KFH40969.1 - 0.00091 17.8 3.0 0.00091 17.8 2.1 1.4 2 0 0 2 2 2 1 Raftlin Methyltransf_4 PF02390.12 KFH40969.1 - 0.0041 16.1 0.1 0.026 13.5 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase NNMT_PNMT_TEMT PF01234.12 KFH40969.1 - 0.017 14.1 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family PH PF00169.24 KFH40970.1 - 0.00011 22.3 0.0 0.00023 21.2 0.0 1.5 1 0 0 1 1 1 1 PH domain Apolipoprotein PF01442.13 KFH40970.1 - 0.0053 16.2 0.2 0.017 14.6 0.1 1.9 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain eRF1_3 PF03465.10 KFH40970.1 - 0.029 14.6 0.1 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 eRF1 domain 3 Seipin PF06775.9 KFH40971.1 - 2.6e-48 164.1 0.0 3.4e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Clr5 PF14420.1 KFH40972.1 - 4.6e-18 64.8 2.0 6.9e-18 64.2 1.4 1.3 1 0 0 1 1 1 1 Clr5 domain Endotoxin_N PF03945.9 KFH40972.1 - 0.2 11.0 0.2 0.27 10.5 0.1 1.1 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain Glyco_hydro_49 PF03718.8 KFH40973.1 - 3.3e-181 603.3 10.1 4e-181 603.0 7.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 49 Pectate_lyase_3 PF12708.2 KFH40973.1 - 6.6e-05 23.1 2.5 0.00016 21.9 1.7 1.6 1 0 0 1 1 1 1 Pectate lyase superfamily protein MFS_1 PF07690.11 KFH40974.1 - 8.4e-36 123.4 28.3 8.4e-36 123.4 19.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 KFH40975.1 - 1.3e-08 33.8 0.0 2.5e-08 32.9 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH40975.1 - 0.0014 18.4 8.4 0.0037 17.1 5.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABM PF03992.11 KFH40977.1 - 1.9e-06 27.8 0.1 2.2e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DNA_primase_lrg PF04104.9 KFH40978.1 - 1.8e-79 266.7 0.0 2.5e-79 266.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit adh_short PF00106.20 KFH40979.1 - 3.3e-19 69.4 0.8 1e-18 67.8 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH40979.1 - 5.6e-05 23.0 0.0 0.00012 21.9 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 KFH40979.1 - 7.8e-05 22.3 0.1 0.00033 20.3 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KFH40979.1 - 0.00011 21.7 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KFH40979.1 - 0.0022 17.6 3.2 0.012 15.3 0.9 2.7 2 1 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 KFH40979.1 - 0.01 15.8 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding 2-Hacid_dh_C PF02826.14 KFH40979.1 - 0.028 13.5 0.0 0.087 11.9 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 KFH40979.1 - 0.054 13.0 0.1 0.15 11.5 0.0 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase MFS_1 PF07690.11 KFH40981.1 - 5.2e-35 120.7 30.2 5.2e-35 120.7 20.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH40981.1 - 1.3e-13 50.4 17.7 2.1e-13 49.6 12.3 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MreB_Mbl PF06723.8 KFH40981.1 - 0.058 11.9 0.0 0.087 11.4 0.0 1.1 1 0 0 1 1 1 0 MreB/Mbl protein DUF4112 PF13430.1 KFH40981.1 - 0.2 11.6 2.4 0.42 10.5 0.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4112) Zn_clus PF00172.13 KFH40982.1 - 5.2e-06 26.2 7.4 9.5e-06 25.4 5.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFH40982.1 - 5.2e-05 22.2 0.0 9.4e-05 21.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain CoA_trans PF01144.18 KFH40984.1 - 5.8e-104 345.9 2.1 4.7e-62 208.9 0.1 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 KFH40984.1 - 0.00012 21.7 0.2 0.00023 20.8 0.1 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Aldedh PF00171.17 KFH40984.1 - 0.028 12.7 0.7 0.043 12.1 0.5 1.2 1 0 0 1 1 1 0 Aldehyde dehydrogenase family NAD_binding_8 PF13450.1 KFH40984.1 - 0.041 13.9 0.1 0.14 12.1 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Ribosomal_60s PF00428.14 KFH40984.1 - 0.52 10.7 5.2 0.42 11.0 1.2 2.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF1660 PF07874.6 KFH40986.1 - 0.045 14.0 2.7 1.4 9.2 0.0 2.4 1 1 1 2 2 2 0 Prophage protein (DUF1660) zf-TFIIB PF13453.1 KFH40986.1 - 0.073 12.2 1.2 3 7.1 0.1 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-FPG_IleRS PF06827.9 KFH40986.1 - 0.13 11.8 3.2 0.36 10.5 0.0 2.3 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Carla_C4 PF01623.12 KFH40986.1 - 0.67 9.7 5.4 3.5 7.4 0.8 2.1 1 1 1 2 2 2 0 Carlavirus putative nucleic acid binding protein MYT1 PF08474.6 KFH40986.1 - 1.9 7.9 10.0 2.2 7.7 6.9 1.1 1 0 0 1 1 1 0 Myelin transcription factor 1 Hemerythrin PF01814.18 KFH40988.1 - 1.2e-14 54.5 3.1 1.7e-14 54.1 2.1 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain APG6 PF04111.7 KFH40988.1 - 0.3 10.0 4.0 3.3 6.6 0.0 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 Occludin_ELL PF07303.8 KFH40988.1 - 0.43 11.3 3.2 0.66 10.7 0.6 2.3 1 1 2 3 3 3 0 Occludin homology domain ING PF12998.2 KFH40988.1 - 0.47 10.7 3.5 9.9 6.5 0.1 2.4 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding CD99L2 PF12301.3 KFH40989.1 - 0.36 10.4 3.7 0.62 9.7 2.3 1.6 1 1 0 1 1 1 0 CD99 antigen like protein 2 MtrF PF09472.5 KFH40989.1 - 0.63 9.3 4.2 0.92 8.8 2.9 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) CFEM PF05730.6 KFH40990.1 - 6e-16 58.0 9.5 7.3e-16 57.7 6.6 1.1 1 0 0 1 1 1 1 CFEM domain Abhydrolase_6 PF12697.2 KFH40991.1 - 4.1e-29 102.0 2.7 5.5e-29 101.6 1.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFH40991.1 - 1e-18 67.7 0.1 3.2e-17 62.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFH40991.1 - 4.3e-14 52.4 0.0 1.2e-13 51.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KFH40991.1 - 0.00049 19.4 0.0 1.1 8.5 0.0 2.4 2 1 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_4 PF08386.5 KFH40991.1 - 0.0013 18.5 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_3 PF07859.8 KFH40991.1 - 0.0069 15.9 0.3 0.022 14.3 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 KFH40991.1 - 0.015 15.5 0.0 0.021 15.0 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain DUF2048 PF09752.4 KFH40991.1 - 0.045 12.6 0.5 0.2 10.5 0.3 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Ndr PF03096.9 KFH40991.1 - 0.07 11.5 0.0 0.12 10.8 0.0 1.3 1 0 0 1 1 1 0 Ndr family NUFIP1 PF10453.4 KFH40992.1 - 3.7e-09 35.9 0.7 1.4e-08 34.1 0.5 2.0 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Mito_fiss_reg PF05308.6 KFH40992.1 - 0.0065 15.8 0.3 0.0065 15.8 0.2 4.9 4 1 0 4 4 4 1 Mitochondrial fission regulator zf-CCCH PF00642.19 KFH40992.1 - 0.045 13.4 5.5 0.094 12.4 3.8 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PV-1 PF06637.6 KFH40992.1 - 0.055 12.0 3.0 0.096 11.2 2.1 1.3 1 0 0 1 1 1 0 PV-1 protein (PLVAP) PFK PF00365.15 KFH40993.1 - 6.8e-162 537.0 4.3 1.9e-116 387.9 2.9 2.1 2 0 0 2 2 2 2 Phosphofructokinase TgMIC1 PF11476.3 KFH40993.1 - 0.84 9.1 4.3 4.5 6.7 0.0 3.4 4 0 0 4 4 4 0 Toxoplasma gondii micronemal protein 1 TgMIC1 SPC25 PF06703.6 KFH40995.1 - 3.9e-45 153.3 0.1 4.7e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Arb1 PF09692.5 KFH40996.1 - 1e-82 278.1 0.0 1.4e-82 277.6 0.0 1.2 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 HEAT PF02985.17 KFH40997.1 - 1.5e-15 55.7 12.2 0.0013 18.6 0.0 10.3 12 0 0 12 12 12 4 HEAT repeat HEAT_2 PF13646.1 KFH40997.1 - 1.5e-13 50.8 15.7 1.4e-06 28.5 0.0 7.3 3 1 4 7 7 7 5 HEAT repeats HEAT_EZ PF13513.1 KFH40997.1 - 8.6e-13 48.3 10.9 2e-08 34.4 0.0 8.5 6 3 4 10 10 10 2 HEAT-like repeat IBN_N PF03810.14 KFH40997.1 - 1.4e-08 34.5 2.0 1.4e-08 34.5 1.4 3.8 5 0 0 5 5 5 1 Importin-beta N-terminal domain MMS19_C PF12460.3 KFH40997.1 - 1.1e-06 27.7 0.5 0.00055 18.7 0.1 3.3 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.3 KFH40997.1 - 5.9e-06 25.8 3.2 1.7 7.9 0.1 5.3 3 2 3 6 6 6 3 CLASP N terminal RIX1 PF08167.7 KFH40997.1 - 0.0026 17.4 2.2 0.9 9.2 0.6 4.4 1 1 4 5 5 5 1 rRNA processing/ribosome biogenesis Cse1 PF08506.5 KFH40997.1 - 0.027 13.0 0.1 2.4 6.6 0.0 3.1 2 1 0 2 2 2 0 Cse1 HEAT_PBS PF03130.11 KFH40997.1 - 0.05 14.0 1.0 1.1e+02 3.7 0.0 4.9 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Arm PF00514.18 KFH40997.1 - 0.08 12.7 6.8 11 6.0 0.0 5.6 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat DUF106 PF01956.11 KFH40998.1 - 5.5e-56 188.7 0.8 7.7e-56 188.2 0.5 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF106 WBP-1 PF11669.3 KFH40998.1 - 0.13 12.3 0.0 7.1 6.7 0.0 2.2 2 0 0 2 2 2 0 WW domain-binding protein 1 Alg6_Alg8 PF03155.10 KFH40999.1 - 3.2e-128 428.5 27.5 3.7e-80 270.0 7.5 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family MMS19_N PF14500.1 KFH41000.1 - 6.5e-45 153.4 0.0 1.7e-44 152.0 0.0 1.6 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 KFH41000.1 - 2.2e-15 56.3 0.0 6.8e-15 54.7 0.0 1.8 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal Med17 PF10156.4 KFH41001.1 - 1.2e-85 287.5 0.0 1.6e-85 287.1 0.0 1.0 1 0 0 1 1 1 1 Subunit 17 of Mediator complex BRO1 PF03097.13 KFH41002.1 - 1.5e-05 23.9 0.0 2.2e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 BRO1-like domain HSL_N PF06350.7 KFH41002.1 - 0.091 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Hormone-sensitive lipase (HSL) N-terminus Ribosomal_60s PF00428.14 KFH41003.1 - 1.2e-27 96.1 12.3 1.4e-27 95.9 8.5 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Pmp3 PF01679.12 KFH41004.1 - 9e-20 70.1 5.4 1.3e-19 69.6 3.7 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Activator_LAG-3 PF11498.3 KFH41004.1 - 1.5 7.4 12.8 2.1 7.0 8.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 ATP11 PF06644.6 KFH41005.1 - 7.6e-83 278.0 0.0 1.1e-82 277.5 0.0 1.2 1 0 0 1 1 1 1 ATP11 protein RNA_pol_Rbc25 PF08292.7 KFH41007.1 - 1.3e-35 122.2 0.1 1.7e-35 121.8 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 KFH41007.1 - 1.2e-15 57.3 0.0 1.7e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 SNF2_N PF00176.18 KFH41008.1 - 7.7e-68 228.4 0.8 1.4e-67 227.5 0.5 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFH41008.1 - 1.9e-11 43.6 0.0 6.4e-11 41.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 KFH41008.1 - 6.2e-08 32.1 2.9 1.2e-07 31.3 2.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFH41008.1 - 4.6e-07 29.7 5.4 1.2e-06 28.4 3.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFH41008.1 - 6.2e-07 28.9 1.5 1.8e-06 27.4 1.1 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFH41008.1 - 1.2e-06 28.2 5.7 3e-06 26.9 3.9 1.7 1 0 0 1 1 1 1 Ring finger domain DEAD PF00270.24 KFH41008.1 - 4.8e-05 22.9 0.4 0.00013 21.4 0.3 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.1 KFH41008.1 - 0.00012 21.7 4.1 0.00029 20.4 2.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KFH41008.1 - 0.00096 18.8 2.0 0.0018 17.9 0.6 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFH41008.1 - 0.0012 18.6 7.4 0.0022 17.8 3.9 2.4 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KFH41008.1 - 0.0038 16.7 1.9 0.02 14.4 1.6 2.1 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain EIIBC-GUT_N PF03612.9 KFH41008.1 - 0.11 12.0 0.4 3 7.4 0.8 2.5 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Baculo_IE-1 PF05290.6 KFH41008.1 - 0.15 11.7 0.5 0.43 10.3 0.3 1.8 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-MIZ PF02891.15 KFH41008.1 - 0.66 9.5 4.8 2.2 7.8 3.3 1.9 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger HMGL-like PF00682.14 KFH41009.1 - 2.4e-59 200.8 0.0 3.9e-59 200.1 0.0 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 KFH41009.1 - 3.6e-22 78.6 0.0 8.7e-22 77.3 0.0 1.7 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain SPT2 PF08243.6 KFH41010.1 - 5e-12 46.1 19.0 2.8e-10 40.5 13.2 2.6 1 1 0 1 1 1 1 SPT2 chromatin protein WD40 PF00400.27 KFH41011.1 - 7.8e-24 82.6 6.8 1e-09 37.9 0.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat Glyco_hydro_61 PF03443.9 KFH41012.1 - 5.6e-50 170.1 0.0 6.8e-50 169.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 HWE_HK PF07536.9 KFH41013.1 - 0.042 14.2 3.1 0.11 12.9 1.2 2.2 2 0 0 2 2 2 0 HWE histidine kinase IncA PF04156.9 KFH41013.1 - 0.35 10.4 13.9 0.13 11.8 3.0 2.7 2 1 0 2 2 2 0 IncA protein Seryl_tRNA_N PF02403.17 KFH41013.1 - 0.7 9.9 6.5 0.33 10.9 2.1 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1748 PF08520.5 KFH41014.1 - 2.2e-31 107.2 0.3 8.3e-27 92.6 0.1 2.1 2 0 0 2 2 2 2 Fungal protein of unknown function (DUF1748) Pyr_redox_3 PF13738.1 KFH41015.1 - 1.7e-21 77.2 0.0 9.5e-21 74.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFH41015.1 - 4.9e-13 48.1 0.1 4.9e-11 41.5 0.1 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KFH41015.1 - 2.6e-11 43.3 0.0 1.1e-10 41.3 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KFH41015.1 - 3.5e-06 26.8 0.0 2.9e-05 23.8 0.0 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KFH41015.1 - 0.00013 21.0 0.0 0.12 11.2 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 KFH41015.1 - 0.12 10.8 0.0 0.19 10.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 KFH41015.1 - 0.14 11.1 0.0 0.39 9.7 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.15 KFH41015.1 - 0.18 11.8 0.0 23 5.1 0.0 3.0 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase ABC_membrane PF00664.18 KFH41016.1 - 2.6e-73 246.7 16.8 1.5e-37 129.5 0.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFH41016.1 - 1.1e-60 203.8 0.0 3.7e-31 108.2 0.0 2.3 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KFH41016.1 - 9.7e-17 60.9 0.6 2.1e-05 23.8 0.0 4.2 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFH41016.1 - 9.6e-15 55.3 0.0 0.0027 17.7 0.0 4.2 4 0 0 4 4 4 3 AAA domain AAA_16 PF13191.1 KFH41016.1 - 1.6e-08 34.7 0.3 0.0042 17.0 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KFH41016.1 - 1.6e-08 33.9 0.7 0.0052 16.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KFH41016.1 - 1.5e-06 29.0 0.0 0.039 14.7 0.0 3.2 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 KFH41016.1 - 2e-06 27.0 0.2 0.055 12.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KFH41016.1 - 2.9e-06 27.4 1.0 0.4 10.8 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KFH41016.1 - 4.5e-06 26.1 0.0 0.63 9.4 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_10 PF12846.2 KFH41016.1 - 7.2e-05 22.3 0.9 0.24 10.7 0.1 3.4 3 0 0 3 3 3 1 AAA-like domain ABC_ATPase PF09818.4 KFH41016.1 - 0.00015 20.5 0.2 0.89 8.0 0.0 3.7 4 0 0 4 4 4 1 Predicted ATPase of the ABC class SbcCD_C PF13558.1 KFH41016.1 - 0.00018 21.3 0.8 0.068 13.0 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 KFH41016.1 - 0.00033 21.0 0.1 0.52 10.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KFH41016.1 - 0.0009 19.5 0.4 1 9.7 0.0 2.7 3 0 0 3 3 2 1 AAA domain Miro PF08477.8 KFH41016.1 - 0.0035 17.8 0.0 0.64 10.5 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 KFH41016.1 - 0.0058 16.5 0.0 2.3 8.2 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_13 PF13166.1 KFH41016.1 - 0.0073 14.8 0.0 0.13 10.6 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 KFH41016.1 - 0.016 15.1 0.0 0.68 9.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KFH41016.1 - 0.019 14.4 0.0 6.3 6.2 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Rad17 PF03215.10 KFH41016.1 - 0.02 13.5 0.0 0.035 12.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_30 PF13604.1 KFH41016.1 - 0.035 13.6 0.0 9.8 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KFH41016.1 - 0.036 13.7 0.2 6.9 6.3 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KFH41016.1 - 0.041 14.0 0.2 18 5.5 0.0 2.9 3 0 0 3 3 2 0 RNA helicase NB-ARC PF00931.17 KFH41016.1 - 0.063 12.1 0.2 6.3 5.5 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_15 PF13175.1 KFH41016.1 - 0.11 11.5 0.0 0.79 8.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 KFH41016.1 - 0.12 12.0 0.2 11 5.6 0.0 2.5 2 0 0 2 2 2 0 NACHT domain DUF87 PF01935.12 KFH41016.1 - 0.17 11.6 0.4 9.2 6.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF3987 PF13148.1 KFH41016.1 - 0.19 10.2 0.0 7.2 5.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Gtr1_RagA PF04670.7 KFH41016.1 - 0.22 10.6 0.2 6.5 5.8 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region KaiC PF06745.8 KFH41016.1 - 0.25 10.4 2.7 7.8 5.5 0.1 3.3 5 0 0 5 5 4 0 KaiC DUF2075 PF09848.4 KFH41016.1 - 0.29 10.0 0.0 1.4 7.7 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AIG1 PF04548.11 KFH41016.1 - 0.73 8.8 1.2 5.3 6.0 0.0 2.3 2 0 0 2 2 2 0 AIG1 family Zn_clus PF00172.13 KFH41017.1 - 2.2e-07 30.6 7.7 3.8e-07 29.9 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Polysacc_synt_4 PF04669.8 KFH41018.1 - 2.1e-26 92.4 0.4 1.2e-25 89.9 0.3 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis Rota_NSP4 PF01452.11 KFH41018.1 - 0.13 11.5 0.9 0.17 11.1 0.1 1.5 2 0 0 2 2 2 0 Rotavirus non structural protein Pkinase PF00069.20 KFH41019.1 - 2.8e-44 151.2 0.0 1e-43 149.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH41019.1 - 1e-30 106.7 0.0 1.5e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH41019.1 - 0.0017 17.3 0.0 0.0042 16.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFH41019.1 - 0.0025 16.8 0.0 0.0078 15.2 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family CTD PF12815.2 KFH41020.1 - 8.9e-26 90.7 61.5 1.3e-19 70.7 25.5 4.6 1 1 2 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5-NGN PF03439.8 KFH41020.1 - 1.4e-23 82.3 0.1 2.3e-23 81.7 0.1 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 KFH41020.1 - 8.9e-19 67.9 10.9 8.9e-19 67.9 7.6 2.5 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 KFH41020.1 - 0.00015 21.3 20.0 0.0033 17.0 1.4 5.0 6 0 0 6 6 6 2 KOW motif PPV_E1_N PF00524.13 KFH41020.1 - 0.0072 16.5 5.4 0.02 15.1 3.8 1.7 1 0 0 1 1 1 1 E1 Protein, N terminal domain MFS_1 PF07690.11 KFH41021.1 - 1.6e-26 92.9 18.7 1.6e-26 92.9 12.9 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily ADH_zinc_N PF00107.21 KFH41022.1 - 4.2e-33 113.6 0.1 2.6e-32 111.1 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFH41022.1 - 4.1e-14 53.5 0.0 7.3e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFH41022.1 - 1.9e-08 34.0 0.0 1.1e-07 31.5 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain 60KD_IMP PF02096.15 KFH41023.1 - 0.046 13.3 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein tRNA_synt_1c_R2 PF04557.10 KFH41023.1 - 3.3 8.4 6.6 0.78 10.4 0.9 2.1 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 PK PF00224.16 KFH41024.1 - 2.3e-168 559.2 3.2 2.9e-168 558.8 2.2 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 KFH41024.1 - 2.4e-31 107.6 0.0 9.3e-31 105.8 0.0 2.1 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 KFH41024.1 - 7.1e-05 21.7 0.6 0.00029 19.7 0.2 2.0 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 KFH41024.1 - 0.011 14.6 0.2 0.27 10.0 0.0 2.2 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Glyco_hydro_2_N PF02837.13 KFH41025.1 - 1.4e-27 96.3 0.2 5.4e-27 94.3 0.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KFH41025.1 - 3.8e-10 40.2 0.1 2e-09 37.8 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 KFH41025.1 - 1.2e-08 34.2 0.0 2.2e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain MFS_1 PF07690.11 KFH41026.1 - 5.1e-48 163.5 31.3 5.1e-48 163.5 21.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH41026.1 - 4.6e-08 32.0 9.6 4.6e-08 32.0 6.6 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KFH41026.1 - 3.1e-06 25.6 0.8 4.7e-06 25.0 0.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 KFH41026.1 - 0.027 12.6 1.5 0.049 11.7 1.1 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector ABM PF03992.11 KFH41028.1 - 9.8e-11 41.5 0.0 7.5e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase AMP_N PF05195.11 KFH41028.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain HeLo PF14479.1 KFH41029.1 - 0.00012 21.8 0.7 0.26 11.0 0.0 2.4 1 1 1 2 2 2 2 Prion-inhibition and propagation TENA_THI-4 PF03070.11 KFH41030.1 - 0.00011 22.0 0.0 0.0097 15.6 0.0 2.1 2 0 0 2 2 2 2 TENA/THI-4/PQQC family DUF1446 PF07287.6 KFH41031.1 - 1.4e-123 412.0 0.1 1.6e-123 411.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) CMD PF02627.15 KFH41032.1 - 0.00012 21.8 0.0 0.0004 20.1 0.0 1.8 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family AA_permease_2 PF13520.1 KFH41033.1 - 9.8e-78 261.5 38.3 1.2e-77 261.2 26.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFH41033.1 - 1.6e-19 69.6 32.7 2.1e-19 69.2 22.7 1.1 1 0 0 1 1 1 1 Amino acid permease FAA_hydrolase PF01557.13 KFH41035.1 - 2.1e-50 171.1 0.0 2.8e-50 170.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 KFH41035.1 - 5.3e-27 93.9 0.0 1.1e-26 92.9 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Myosin_N PF02736.14 KFH41035.1 - 0.28 10.8 2.4 0.26 10.9 0.2 1.9 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain DUF814 PF05670.8 KFH41036.1 - 3.1e-11 43.0 4.5 8.8e-09 35.1 0.5 3.6 2 1 0 2 2 2 1 Domain of unknown function (DUF814) AAA_11 PF13086.1 KFH41036.1 - 0.029 13.9 3.6 0.041 13.4 2.5 1.2 1 0 0 1 1 1 0 AAA domain Flavokinase PF01687.12 KFH41037.1 - 5.9e-09 35.8 0.0 8.8e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Riboflavin kinase Sugar_tr PF00083.19 KFH41038.1 - 1.1e-83 281.3 20.8 1.3e-83 281.1 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH41038.1 - 2e-16 59.6 41.7 9.7e-12 44.2 7.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short_C2 PF13561.1 KFH41039.1 - 5.7e-27 95.0 0.4 7.7e-27 94.5 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFH41039.1 - 7.7e-27 94.2 4.4 1.1e-26 93.7 3.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH41039.1 - 3.6e-10 39.7 2.2 5.6e-10 39.1 1.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFH41039.1 - 0.0011 18.4 0.1 0.0042 16.5 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 KFH41039.1 - 0.018 14.7 0.3 0.03 13.9 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 KFH41039.1 - 0.044 12.8 0.0 0.12 11.4 0.0 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF3425 PF11905.3 KFH41040.1 - 2.7e-19 69.4 1.7 5.8e-19 68.3 1.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KFH41040.1 - 1.5e-05 24.8 4.9 0.0046 16.8 1.4 2.5 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 KFH41040.1 - 0.002 17.9 0.1 0.002 17.9 0.1 2.4 1 1 1 2 2 2 1 Basic region leucine zipper DUF972 PF06156.8 KFH41040.1 - 0.02 15.2 0.0 0.062 13.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF972) MAD PF05557.8 KFH41040.1 - 0.058 11.4 1.6 0.091 10.8 1.1 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein CBM_21 PF03370.8 KFH41041.1 - 1.2e-35 121.9 0.1 2e-35 121.1 0.1 1.4 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit AA_permease_2 PF13520.1 KFH41042.1 - 4.6e-40 137.4 33.5 6.1e-40 137.0 23.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFH41042.1 - 1.9e-21 75.9 31.9 2.7e-21 75.4 22.1 1.0 1 0 0 1 1 1 1 Amino acid permease CTV_P6 PF06706.6 KFH41042.1 - 0.04 13.4 1.6 0.62 9.6 0.0 3.1 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein GAPT PF11770.3 KFH41042.1 - 0.05 13.2 0.6 0.12 12.0 0.4 1.6 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) GST_N_3 PF13417.1 KFH41043.1 - 1e-10 41.6 0.1 1.8e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFH41043.1 - 1.3e-07 31.4 0.0 2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFH41043.1 - 0.00013 21.8 0.0 0.00022 21.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KFH41043.1 - 0.00023 21.2 0.0 0.00076 19.5 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFH41043.1 - 0.072 12.9 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Peptidase_M24 PF00557.19 KFH41044.1 - 3.6e-55 186.7 0.0 4.9e-55 186.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KFH41044.1 - 4.8e-27 93.9 0.0 8.9e-27 93.1 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain UCH PF00443.24 KFH41045.1 - 1.2e-42 145.9 0.0 2.1e-42 145.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KFH41045.1 - 4.8e-24 84.2 12.0 2.8e-19 68.9 2.1 2.9 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 KFH41045.1 - 2.1e-20 71.9 0.0 1.2e-09 37.6 0.0 2.9 3 0 0 3 3 3 2 UBA/TS-N domain UCH_1 PF13423.1 KFH41045.1 - 5.5e-20 71.9 0.0 1.1e-08 34.8 0.0 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RPE65 PF03055.10 KFH41046.1 - 4.6e-115 384.9 0.0 5.2e-115 384.7 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Patatin PF01734.17 KFH41047.1 - 7.5e-26 91.3 0.0 1.2e-25 90.6 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase FTA4 PF13093.1 KFH41049.1 - 5e-42 143.7 0.0 6.3e-42 143.4 0.0 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Nnf1 PF03980.9 KFH41049.1 - 0.049 13.6 1.0 0.12 12.4 0.7 1.8 1 1 0 1 1 1 0 Nnf1 Seryl_tRNA_N PF02403.17 KFH41049.1 - 0.55 10.2 3.6 0.66 10.0 0.8 2.2 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ABC2_membrane PF01061.19 KFH41050.1 - 5.2e-36 123.7 18.8 9.7e-36 122.9 13.1 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 KFH41050.1 - 3.9e-25 88.7 0.0 7.2e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KFH41050.1 - 9.7e-09 35.5 0.0 2.9e-08 34.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain hEGF PF12661.2 KFH41050.1 - 0.0001 22.1 21.3 0.016 15.2 2.4 4.4 3 0 0 3 3 3 2 Human growth factor-like EGF AAA_25 PF13481.1 KFH41050.1 - 0.00015 21.2 0.0 0.0048 16.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KFH41050.1 - 0.0023 17.3 0.1 0.0053 16.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 KFH41050.1 - 0.0027 16.9 0.0 0.0055 15.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC2_membrane_3 PF12698.2 KFH41050.1 - 0.0097 14.9 27.1 0.032 13.2 18.6 1.8 1 1 0 1 1 1 1 ABC-2 family transporter protein NACHT PF05729.7 KFH41050.1 - 0.027 14.1 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.1 KFH41050.1 - 0.034 14.3 0.0 0.085 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 KFH41050.1 - 0.047 12.7 0.0 2 7.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 KFH41050.1 - 0.059 13.6 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KFH41050.1 - 0.097 13.4 0.0 0.19 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KFH41050.1 - 0.13 12.5 0.3 0.24 11.6 0.2 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KFH41050.1 - 0.14 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KFH41050.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KFH41050.1 - 0.18 11.6 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KFH41050.1 - 0.19 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Laminin_EGF PF00053.19 KFH41050.1 - 0.2 11.5 22.7 0.079 12.9 2.1 3.5 3 0 0 3 3 3 0 Laminin EGF-like (Domains III and V) UPF0079 PF02367.12 KFH41050.1 - 0.22 11.1 0.1 0.45 10.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Aa_trans PF01490.13 KFH41051.1 - 1.7e-73 247.4 22.0 2e-73 247.2 15.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Claudin_2 PF13903.1 KFH41051.1 - 9.5 5.8 13.8 0.079 12.6 0.8 3.2 4 1 0 4 4 4 0 PMP-22/EMP/MP20/Claudin tight junction NGP1NT PF08153.7 KFH41053.1 - 1.2e-50 170.7 0.4 2.1e-50 169.9 0.3 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 KFH41053.1 - 2.1e-18 66.3 0.0 3.6e-14 52.7 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 KFH41053.1 - 6.3e-06 26.1 0.8 0.018 14.8 0.1 3.5 2 1 1 3 3 3 1 Dynamin family FeoB_N PF02421.13 KFH41053.1 - 7.6e-05 22.0 0.0 0.00058 19.1 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KFH41053.1 - 0.00033 20.1 0.0 0.14 11.5 0.0 3.1 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Arf PF00025.16 KFH41053.1 - 0.0043 16.3 0.0 0.88 8.7 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 KFH41053.1 - 0.0071 16.8 0.4 0.4 11.1 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 KFH41053.1 - 0.013 14.6 0.0 0.033 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 HORMA PF02301.13 KFH41054.1 - 2.7e-45 154.4 0.0 3.2e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 HORMA domain DUF1682 PF07946.9 KFH41054.1 - 0.0072 15.2 0.2 0.01 14.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) NifU_N PF01592.11 KFH41055.1 - 1.2e-52 177.1 0.1 1.6e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain DUF4185 PF13810.1 KFH41056.1 - 2.1e-06 26.8 0.8 2.1e-06 26.8 0.6 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4185) DUF3642 PF12182.3 KFH41056.1 - 0.21 12.0 0.0 0.21 12.0 0.0 1.7 2 0 0 2 2 2 0 Bacterial lipoprotein p450 PF00067.17 KFH41057.1 - 7.5e-73 245.6 0.0 9.6e-73 245.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.1 KFH41058.1 - 1e-25 90.9 0.0 1.2e-25 90.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFH41058.1 - 9.7e-24 84.1 0.3 1.2e-23 83.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH41058.1 - 2.1e-11 43.8 0.1 2.9e-11 43.3 0.1 1.2 1 0 0 1 1 1 1 KR domain 7tm_2 PF00002.19 KFH41061.1 - 0.00015 20.9 9.6 0.00048 19.2 6.7 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 KFH41061.1 - 0.0045 15.9 3.4 0.0088 14.9 2.4 1.5 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor DC_STAMP PF07782.8 KFH41061.1 - 0.018 14.6 0.1 7.7 6.0 0.0 2.6 2 0 0 2 2 2 0 DC-STAMP-like protein TauD PF02668.11 KFH41062.1 - 4.5e-18 65.8 0.2 6.3e-18 65.3 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Cellulase PF00150.13 KFH41063.1 - 6.8e-32 110.7 0.1 8.3e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PBP1_TM PF14812.1 KFH41063.1 - 0.00031 20.9 0.0 0.00063 20.0 0.0 1.5 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal FolB PF02152.13 KFH41065.1 - 3.2e-17 62.7 0.0 1.8e-14 53.8 0.0 2.5 2 1 0 2 2 2 2 Dihydroneopterin aldolase IMS_C PF11799.3 KFH41065.1 - 0.13 12.1 0.0 1.6 8.7 0.0 2.4 2 1 0 2 2 2 0 impB/mucB/samB family C-terminal domain Abhydrolase_3 PF07859.8 KFH41066.1 - 1.5e-21 76.9 0.0 2e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFH41066.1 - 4.5e-10 39.4 0.0 7.7e-10 38.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KFH41066.1 - 8.7e-09 34.6 0.0 3.5e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 Carboxylesterase family AXE1 PF05448.7 KFH41066.1 - 2.1e-08 33.0 0.0 0.0022 16.5 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 KFH41066.1 - 2.8e-08 33.2 0.0 5.6e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KFH41066.1 - 6.6e-05 22.8 0.8 9.6e-05 22.3 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KFH41066.1 - 0.00019 20.4 0.0 0.00025 20.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase PF00756.15 KFH41066.1 - 0.0018 17.7 0.1 0.007 15.8 0.1 1.8 1 1 0 1 1 1 1 Putative esterase Esterase_phd PF10503.4 KFH41066.1 - 0.033 13.4 0.0 0.26 10.5 0.0 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase PaO PF08417.7 KFH41066.1 - 0.095 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Pheophorbide a oxygenase F-box-like PF12937.2 KFH41068.1 - 0.00033 20.3 1.3 0.0047 16.6 0.1 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KFH41068.1 - 0.0026 17.3 0.7 0.013 15.1 0.0 2.5 3 0 0 3 3 3 1 F-box domain F-box-like_2 PF13013.1 KFH41068.1 - 0.024 14.3 0.2 9.9 5.9 0.1 2.7 2 0 0 2 2 2 0 F-box-like domain Ammonium_transp PF00909.16 KFH41069.1 - 2.8e-111 371.8 32.8 3.3e-111 371.6 22.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Zn_clus PF00172.13 KFH41070.1 - 0.0048 16.7 6.8 0.0097 15.7 4.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CRT10 PF08728.5 KFH41071.1 - 1.3e-12 46.5 0.0 7.1e-08 30.9 0.0 2.2 2 0 0 2 2 2 2 CRT10 Nop14 PF04147.7 KFH41071.1 - 0.12 10.2 8.5 0.18 9.6 5.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KFH41071.1 - 0.28 9.1 0.8 0.4 8.6 0.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 KFH41071.1 - 0.49 8.8 9.7 0.79 8.1 6.7 1.2 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 KFH41071.1 - 7.8 5.6 13.6 13 4.9 9.4 1.2 1 0 0 1 1 1 0 SDA1 Mito_fiss_reg PF05308.6 KFH41073.1 - 0.22 10.8 3.5 0.23 10.7 2.4 1.3 1 1 0 1 1 1 0 Mitochondrial fission regulator DUF3605 PF12239.3 KFH41074.1 - 2.9e-50 170.1 2.3 8.1e-49 165.5 1.6 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) UDPGP PF01704.13 KFH41075.1 - 3e-13 49.0 0.0 7e-09 34.6 0.0 2.1 1 1 1 2 2 2 2 UTP--glucose-1-phosphate uridylyltransferase His_Phos_2 PF00328.17 KFH41076.1 - 7.5e-38 130.7 0.0 9e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Hydantoinase_B PF02538.9 KFH41077.1 - 5.9e-196 651.7 0.0 4.5e-189 629.0 0.0 2.1 1 1 1 2 2 2 2 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KFH41077.1 - 9.1e-96 320.3 0.6 1.8e-95 319.4 0.4 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KFH41077.1 - 2.8e-58 196.3 0.7 1.5e-56 190.6 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Aconitase PF00330.15 KFH41078.1 - 2.3e-147 491.2 0.0 6.8e-147 489.6 0.0 1.7 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KFH41078.1 - 6.4e-39 133.0 0.0 1.1e-38 132.3 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.8 KFH41078.1 - 0.014 14.0 0.0 0.021 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Pyridoxal_deC PF00282.14 KFH41079.1 - 1.2e-25 89.7 0.0 1.5e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 KFH41079.1 - 4.2e-06 26.1 0.0 4.9e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KFH41079.1 - 0.044 12.5 0.0 0.076 11.7 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Aminotran_1_2 PF00155.16 KFH41079.1 - 0.092 11.6 0.0 0.23 10.3 0.0 1.6 2 0 0 2 2 2 0 Aminotransferase class I and II Alb1 PF09135.6 KFH41080.1 - 0.019 15.5 0.1 0.037 14.6 0.1 1.5 1 0 0 1 1 1 0 Alb1 UAF_Rrn10 PF05234.6 KFH41080.1 - 0.15 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 UAF complex subunit Rrn10 APG5 PF04106.7 KFH41081.1 - 1.1e-43 149.0 0.0 2.4e-43 147.9 0.0 1.6 1 1 0 1 1 1 1 Autophagy protein Apg5 MARVEL PF01284.18 KFH41082.1 - 1.4e-15 57.3 13.2 1.7e-15 57.0 9.2 1.1 1 0 0 1 1 1 1 Membrane-associating domain PepSY_TM_2 PF13703.1 KFH41082.1 - 0.017 15.3 1.4 0.017 15.3 1.0 2.9 2 1 0 2 2 2 0 PepSY-associated TM helix 7TM_GPCR_Srx PF10328.4 KFH41082.1 - 0.047 12.8 0.0 0.061 12.4 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF2976 PF11190.3 KFH41082.1 - 0.075 12.5 3.5 0.22 11.0 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) HemY_N PF07219.8 KFH41082.1 - 8.8 5.9 9.7 0.76 9.3 1.2 2.2 2 0 0 2 2 2 0 HemY protein N-terminus NmrA PF05368.8 KFH41083.1 - 3.1e-08 33.1 0.1 8.1e-07 28.5 0.0 2.6 2 1 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 KFH41083.1 - 3.8e-07 30.3 0.0 8.1e-07 29.2 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 KFH41083.1 - 0.00034 20.7 0.0 0.00055 20.0 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 KFH41083.1 - 0.0032 16.5 0.0 0.0044 16.0 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 KFH41083.1 - 0.013 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Ribosomal_60s PF00428.14 KFH41083.1 - 0.025 14.9 2.8 0.046 14.1 1.9 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein NAD_binding_2 PF03446.10 KFH41083.1 - 0.027 14.3 0.0 1.6 8.5 0.0 2.5 2 1 1 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 KFH41083.1 - 0.036 13.5 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 KFH41083.1 - 0.09 13.2 0.0 0.94 9.9 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 KFH41083.1 - 0.16 10.6 0.0 0.24 10.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Nucleopor_Nup85 PF07575.8 KFH41084.1 - 2e-09 36.2 0.8 5.2e-08 31.5 0.2 2.9 2 1 0 2 2 2 1 Nup85 Nucleoporin ADH_N PF08240.7 KFH41085.1 - 1.2e-23 82.9 1.1 4.8e-23 81.0 0.8 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFH41085.1 - 2.3e-19 69.2 0.2 4.3e-19 68.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 KFH41085.1 - 0.0065 15.8 0.3 0.011 15.1 0.2 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 KFH41085.1 - 0.11 12.5 0.1 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain zf-AN1 PF01428.11 KFH41086.1 - 2e-11 43.5 12.4 2.8e-11 43.0 8.6 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger HhH-GPD PF00730.20 KFH41087.1 - 6.3e-18 65.0 0.0 1.2e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KFH41087.1 - 4.2e-08 32.4 0.0 1.1e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif UPF0561 PF10573.4 KFH41087.1 - 0.0069 16.2 0.4 0.059 13.2 0.2 2.5 2 0 0 2 2 2 1 Uncharacterised protein family UPF0561 DUF2462 PF09495.5 KFH41089.1 - 2.4e-06 28.1 11.9 3.2e-06 27.7 8.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) Peptidase_S30 PF01577.11 KFH41089.1 - 0.13 11.6 2.8 0.14 11.5 1.9 1.1 1 0 0 1 1 1 0 Potyvirus P1 protease WD40 PF00400.27 KFH41090.1 - 3.8e-29 99.4 12.7 6.5e-08 32.1 1.1 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat PQQ_2 PF13360.1 KFH41090.1 - 0.0022 17.4 0.0 0.71 9.2 0.0 2.8 2 1 0 2 2 2 2 PQQ-like domain Nup160 PF11715.3 KFH41090.1 - 0.0025 16.0 4.0 0.46 8.5 0.1 3.5 2 1 0 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 KFH41090.1 - 0.012 15.2 0.0 1.2 8.8 0.0 2.8 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Acyl-CoA_dh_1 PF00441.19 KFH41092.1 - 1.5e-14 54.3 0.0 3.7e-13 49.8 0.0 2.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFH41092.1 - 3.5e-08 32.8 0.3 1.1e-07 31.2 0.2 2.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KFH41092.1 - 0.00027 21.1 1.7 0.02 15.1 0.0 3.2 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain A_deaminase PF00962.17 KFH41093.1 - 4e-38 131.1 0.0 4.4e-37 127.7 0.0 2.1 1 1 0 1 1 1 1 Adenosine/AMP deaminase HEAT PF02985.17 KFH41094.1 - 2.8e-11 42.5 2.1 0.061 13.4 0.0 5.7 5 0 0 5 5 5 4 HEAT repeat Pkinase PF00069.20 KFH41094.1 - 1.6e-09 37.3 0.0 3.2e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH41094.1 - 9.5e-07 28.1 0.0 1.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.1 KFH41094.1 - 4.4e-06 27.0 0.1 0.045 14.2 0.0 3.0 2 0 0 2 2 2 2 HEAT-like repeat HEAT_2 PF13646.1 KFH41094.1 - 8.5e-05 22.7 0.0 0.0012 19.0 0.0 2.6 2 0 0 2 2 2 1 HEAT repeats Cnd1 PF12717.2 KFH41094.1 - 0.006 16.4 0.0 0.039 13.7 0.0 2.1 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Kinase-like PF14531.1 KFH41094.1 - 0.0064 15.4 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Adaptin_N PF01602.15 KFH41094.1 - 0.054 11.8 0.0 1.7 6.8 0.0 2.0 1 1 1 2 2 2 0 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 KFH41094.1 - 0.14 12.5 0.0 4.8 7.6 0.0 2.8 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region Hist_deacetyl PF00850.14 KFH41096.1 - 1.3e-77 261.2 0.0 1.2e-76 258.0 0.0 2.1 1 1 1 2 2 2 2 Histone deacetylase domain URO-D PF01208.12 KFH41097.1 - 1.9e-120 401.9 0.0 2.2e-120 401.7 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) GTP_EFTU PF00009.22 KFH41098.1 - 4.1e-09 36.1 0.0 2.4e-08 33.6 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain WD40 PF00400.27 KFH41099.1 - 2.8e-12 46.0 1.0 0.88 9.5 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Cofilin_ADF PF00241.15 KFH41099.1 - 0.042 13.7 0.7 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 Cofilin/tropomyosin-type actin-binding protein HA2 PF04408.18 KFH41100.1 - 6e-18 64.7 0.0 1.5e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KFH41100.1 - 4.7e-16 58.6 0.0 9.9e-16 57.5 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KFH41100.1 - 2.6e-13 49.6 0.0 8.4e-13 47.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFH41100.1 - 2.3e-06 27.2 0.0 1.2e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KFH41100.1 - 0.00052 20.1 0.0 0.0024 18.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KFH41100.1 - 0.0038 16.1 0.0 0.0063 15.4 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.22 KFH41100.1 - 0.013 15.7 0.0 0.038 14.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Sigma54_activ_2 PF14532.1 KFH41100.1 - 0.015 15.3 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.1 KFH41100.1 - 0.021 14.3 0.0 0.048 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.15 KFH41100.1 - 0.08 11.6 0.3 0.15 10.6 0.2 1.4 1 0 0 1 1 1 0 G-protein alpha subunit Velvet PF11754.3 KFH41101.1 - 1.1e-33 116.5 0.0 2.5e-33 115.3 0.0 1.5 1 1 0 1 1 1 1 Velvet factor FOLN PF09289.5 KFH41102.1 - 0.014 15.2 1.5 0.036 13.9 1.0 1.7 1 0 0 1 1 1 0 Follistatin/Osteonectin-like EGF domain Ion_trans PF00520.26 KFH41104.1 - 9.2e-100 331.9 84.6 1.6e-33 115.6 8.4 5.4 4 1 0 4 4 4 4 Ion transport protein PKD_channel PF08016.7 KFH41104.1 - 3.7e-05 22.3 63.3 0.0078 14.6 0.5 7.7 6 2 1 7 7 7 7 Polycystin cation channel HMG_box PF00505.14 KFH41105.1 - 0.0017 18.5 0.1 0.0034 17.6 0.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box MutS_V PF00488.16 KFH41106.1 - 3.5e-58 196.7 0.0 5.6e-58 196.1 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KFH41106.1 - 2.7e-08 33.8 0.1 7.4e-08 32.4 0.0 1.8 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 KFH41106.1 - 0.044 13.9 0.0 0.14 12.3 0.0 1.9 1 1 0 1 1 1 0 MutS family domain IV DAP3 PF10236.4 KFH41106.1 - 0.21 10.4 0.0 0.65 8.8 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 HisG PF01634.13 KFH41107.1 - 1e-47 161.7 0.0 1.7e-47 161.0 0.0 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 KFH41107.1 - 3.7e-27 94.0 0.1 8.2e-27 92.9 0.1 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain DUF508 PF04370.7 KFH41108.1 - 0.15 11.6 0.2 0.23 11.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF508) DUF3602 PF12223.3 KFH41109.1 - 1.3e-15 57.5 11.1 1.5e-12 47.7 1.4 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Rab5ip PF07019.7 KFH41110.1 - 1.5e-22 79.4 5.0 1.8e-22 79.2 3.5 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) SNARE PF05739.14 KFH41111.1 - 3.5e-05 23.3 5.2 3.5e-05 23.3 3.6 2.4 2 0 0 2 2 2 1 SNARE domain V-SNARE_C PF12352.3 KFH41111.1 - 0.078 13.0 5.4 0.035 14.1 1.7 1.9 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Complex1_LYR PF05347.10 KFH41114.1 - 1.9e-09 37.1 0.0 3e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KFH41114.1 - 2.3e-07 30.8 0.2 3.3e-07 30.4 0.2 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KFH41114.1 - 9.4e-05 22.8 0.2 0.00015 22.2 0.1 1.3 1 1 0 1 1 1 1 Complex1_LYR-like PMT_C PF11647.3 KFH41114.1 - 0.14 11.7 0.4 1.2 8.8 0.1 2.0 2 0 0 2 2 2 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 ING PF12998.2 KFH41115.1 - 1.6e-25 89.4 4.3 2.8e-25 88.6 3.0 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding DUF1704 PF08014.6 KFH41115.1 - 0.095 11.7 0.1 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1704) DUF765 PF05570.6 KFH41115.1 - 0.13 12.2 0.4 0.13 12.2 0.2 3.5 3 0 0 3 3 3 0 Circovirus protein of unknown function (DUF765) PHD PF00628.24 KFH41116.1 - 1.1e-08 34.5 8.4 2.2e-08 33.6 5.8 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KFH41116.1 - 0.002 17.3 4.4 0.004 16.4 3.0 1.4 1 0 0 1 1 1 1 PHD-finger MMgT PF10270.4 KFH41117.1 - 2e-29 102.1 0.0 2.3e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter ABC_tran PF00005.22 KFH41119.1 - 3.5e-49 166.6 0.2 1.1e-25 90.5 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 KFH41119.1 - 6.7e-30 104.2 34.8 5.2e-18 65.2 11.8 3.1 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.1 KFH41119.1 - 4.7e-22 79.2 0.9 1.5e-08 34.9 0.1 4.3 3 1 0 3 3 3 3 AAA domain AAA_29 PF13555.1 KFH41119.1 - 1.1e-11 44.0 1.6 1.7e-05 24.2 0.2 3.4 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.14 KFH41119.1 - 6.8e-09 35.2 1.8 0.067 12.4 0.1 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KFH41119.1 - 6.5e-07 29.8 6.3 0.0014 18.9 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 KFH41119.1 - 1.1e-05 25.5 1.6 0.33 10.9 0.1 3.8 3 0 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 KFH41119.1 - 0.00011 21.4 0.5 0.46 9.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 KFH41119.1 - 0.0018 17.3 0.6 3.1 6.8 0.0 3.2 3 0 0 3 3 3 1 Zeta toxin AAA_15 PF13175.1 KFH41119.1 - 0.0037 16.3 0.0 0.36 9.8 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 KFH41119.1 - 0.0049 16.2 0.6 2 7.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KFH41119.1 - 0.0078 15.8 0.4 2.8 7.4 0.1 2.7 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 KFH41119.1 - 0.02 13.6 1.5 0.17 10.6 0.1 2.3 2 0 0 2 2 2 0 ArgK protein AAA_33 PF13671.1 KFH41119.1 - 0.03 14.2 0.2 7.3 6.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 KFH41119.1 - 0.032 13.6 0.2 3.6 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_22 PF13401.1 KFH41119.1 - 0.037 14.1 1.7 3.7 7.6 0.2 3.1 2 2 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KFH41119.1 - 0.044 13.7 0.9 3.7 7.4 0.5 2.4 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 KFH41119.1 - 0.074 12.4 1.7 5.4 6.4 0.2 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.18 KFH41119.1 - 0.13 12.2 0.1 34 4.4 0.1 3.3 3 0 0 3 3 3 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 KFH41119.1 - 0.16 11.4 0.4 1.4 8.3 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.1 KFH41119.1 - 0.19 12.5 0.2 18 6.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KFH41119.1 - 0.22 11.2 4.8 7.3 6.4 0.5 3.4 3 0 0 3 3 3 0 Part of AAA domain G-alpha PF00503.15 KFH41119.1 - 0.37 9.4 0.0 2.7 6.5 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit DUF87 PF01935.12 KFH41119.1 - 0.39 10.5 1.9 18 5.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_13 PF13166.1 KFH41119.1 - 1.7 7.0 0.1 26 3.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain UCH_1 PF13423.1 KFH41120.1 - 5.1e-56 190.2 0.0 7.3e-56 189.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 KFH41120.1 - 2.4e-28 99.4 0.0 3.1e-27 95.8 0.0 2.2 2 0 0 2 2 2 1 Exonuclease UCH PF00443.24 KFH41120.1 - 1.4e-09 37.5 0.0 5.8e-09 35.4 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_H_2 PF13482.1 KFH41120.1 - 0.11 12.3 0.1 0.24 11.1 0.1 1.5 1 0 0 1 1 1 0 RNase_H superfamily Zn_clus PF00172.13 KFH41121.1 - 1.3e-09 37.8 11.1 2.2e-09 37.0 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFH41121.1 - 2.4e-07 29.8 0.0 5.3e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_25 PF13649.1 KFH41122.1 - 3e-08 33.9 0.0 5.1e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH41122.1 - 8.4e-08 31.9 0.0 1.1e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH41122.1 - 0.00023 21.6 0.0 0.00039 20.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH41122.1 - 0.00061 20.2 0.0 0.0013 19.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH41122.1 - 0.001 19.6 0.0 0.002 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFH41122.1 - 0.0046 16.9 0.0 0.0074 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain P53_TAD PF08563.6 KFH41122.1 - 0.043 12.8 0.1 0.082 11.9 0.0 1.4 1 0 0 1 1 1 0 P53 transactivation motif Methyltransf_23 PF13489.1 KFH41122.1 - 0.08 12.6 0.0 0.12 12.1 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain PEPCK_ATP PF01293.15 KFH41123.1 - 2e-213 709.1 0.0 2.4e-213 708.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_18 PF13238.1 KFH41123.1 - 0.032 14.5 0.0 11 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KFH41123.1 - 0.096 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ran-binding PF05508.6 KFH41124.1 - 1.1e-92 310.2 0.0 1.7e-92 309.6 0.0 1.3 1 0 0 1 1 1 1 RanGTP-binding protein PHY PF00360.15 KFH41125.1 - 1.1e-26 93.1 0.0 2.3e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region Response_reg PF00072.19 KFH41125.1 - 1.7e-17 63.4 0.0 7.2e-17 61.4 0.0 2.1 1 1 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 KFH41125.1 - 4.6e-16 58.5 0.1 1.1e-15 57.3 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.21 KFH41125.1 - 2.3e-15 57.0 0.0 6.3e-15 55.6 0.0 1.8 1 0 0 1 1 1 1 GAF domain HisKA PF00512.20 KFH41125.1 - 1.1e-12 47.7 0.5 3.8e-12 46.0 0.4 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 KFH41125.1 - 4.2e-08 33.6 0.0 1.4e-07 31.9 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 KFH41125.1 - 0.057 13.7 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 PAS domain PAS_3 PF08447.6 KFH41125.1 - 0.07 13.2 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 PAS fold Cupin_8 PF13621.1 KFH41126.1 - 1.4e-24 86.9 0.0 1.7e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KFH41126.1 - 0.0059 15.8 0.0 0.0097 15.1 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.6 KFH41126.1 - 0.015 14.7 0.0 0.033 13.6 0.0 1.5 1 0 0 1 1 1 0 Cupin domain JmjC PF02373.17 KFH41126.1 - 0.037 14.2 0.0 0.26 11.5 0.0 2.4 2 1 0 2 2 2 0 JmjC domain, hydroxylase CK_II_beta PF01214.13 KFH41127.1 - 1.6e-75 252.7 0.0 2.6e-75 251.9 0.0 1.3 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.3 KFH41127.1 - 0.011 16.3 9.1 0.017 15.7 2.3 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal CENP-B_dimeris PF09026.5 KFH41127.1 - 1.6 9.0 10.0 1.8 8.8 4.2 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 KFH41127.1 - 6.9 6.2 7.4 6.3 6.3 2.6 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region Copper-fist PF00649.13 KFH41128.1 - 1.3e-22 78.6 1.9 1.3e-22 78.6 1.3 3.9 1 1 3 4 4 4 1 Copper fist DNA binding domain GTP_EFTU PF00009.22 KFH41130.1 - 3e-44 150.7 0.0 5.3e-44 149.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KFH41130.1 - 3.2e-21 75.3 0.1 7.8e-21 74.0 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KFH41130.1 - 9.4e-09 35.2 0.2 2.7e-08 33.8 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KFH41130.1 - 9.6e-05 22.3 0.1 0.0003 20.7 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 KFH41130.1 - 0.51 8.9 6.1 0.12 10.9 1.2 1.9 2 0 0 2 2 2 0 G-protein alpha subunit Mito_carr PF00153.22 KFH41131.1 - 2.3e-71 235.5 1.9 1.1e-25 89.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 KFH41131.1 - 0.021 14.8 4.8 0.23 11.5 0.0 3.3 3 1 0 4 4 4 0 Tim17/Tim22/Tim23/Pmp24 family PNP_UDP_1 PF01048.15 KFH41132.1 - 1.9e-38 131.7 0.1 2.2e-38 131.5 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily DHBP_synthase PF00926.14 KFH41133.1 - 2.2e-67 226.0 0.0 9e-67 224.0 0.0 1.7 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase H2TH PF06831.9 KFH41134.1 - 6e-21 74.0 0.0 1e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.19 KFH41134.1 - 4.7e-07 30.1 0.1 9.2e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain FbpA PF05833.6 KFH41134.1 - 0.0096 14.5 0.0 0.018 13.6 0.0 1.4 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Fungal_trans_2 PF11951.3 KFH41135.1 - 9.7e-25 86.9 0.2 1.4e-24 86.4 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Herpes_DNAp_acc PF04929.7 KFH41135.1 - 2.1 7.2 3.1 3.3 6.5 2.1 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DAO PF01266.19 KFH41136.1 - 9.5e-42 143.1 0.0 2.2e-41 141.9 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFH41136.1 - 8e-08 32.4 0.1 0.018 14.9 0.0 3.4 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFH41136.1 - 7.8e-06 25.7 0.1 0.018 14.8 0.0 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KFH41136.1 - 3.9e-05 23.5 0.0 0.00011 22.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KFH41136.1 - 9e-05 22.8 0.0 0.00024 21.4 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KFH41136.1 - 0.00036 19.5 0.3 0.42 9.4 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Trp_halogenase PF04820.9 KFH41136.1 - 0.00043 19.0 0.2 0.49 8.9 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.19 KFH41136.1 - 0.0022 16.9 5.3 0.44 9.3 0.0 2.2 1 1 1 2 2 2 2 FAD binding domain FAD_binding_3 PF01494.14 KFH41136.1 - 0.0026 16.8 0.1 0.0041 16.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KFH41136.1 - 0.0078 16.2 0.0 0.49 10.4 0.1 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 KFH41136.1 - 0.013 15.3 0.5 0.026 14.3 0.4 1.4 1 0 0 1 1 1 0 ThiF family 3HCDH_N PF02737.13 KFH41136.1 - 0.018 14.7 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.20 KFH41136.1 - 0.049 13.5 0.1 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase ApbA PF02558.11 KFH41136.1 - 0.056 12.8 0.1 0.092 12.1 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 KFH41136.1 - 0.072 12.1 0.3 0.16 11.0 0.1 1.5 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.13 KFH41136.1 - 0.094 12.7 0.0 0.24 11.4 0.0 1.7 2 0 0 2 2 1 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.18 KFH41136.1 - 0.098 12.3 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Saccharop_dh PF03435.13 KFH41136.1 - 0.12 11.3 0.1 0.29 10.0 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase PALP PF00291.20 KFH41136.1 - 0.12 11.5 0.2 0.22 10.6 0.1 1.4 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Lycopene_cycl PF05834.7 KFH41136.1 - 0.13 11.1 0.2 0.39 9.5 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 KFH41136.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding zf-Nse PF11789.3 KFH41137.1 - 1.1e-22 79.2 0.6 2.4e-22 78.1 0.4 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.15 KFH41137.1 - 0.00036 19.9 0.5 0.00077 18.9 0.4 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RING_2 PF13639.1 KFH41137.1 - 0.023 14.4 0.3 0.043 13.6 0.2 1.5 1 0 0 1 1 1 0 Ring finger domain Exonuc_VII_L PF02601.10 KFH41137.1 - 0.065 12.4 0.5 0.12 11.5 0.4 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-RING_UBOX PF13445.1 KFH41137.1 - 0.099 12.3 0.2 0.26 11.0 0.2 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-Apc11 PF12861.2 KFH41137.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FUSC PF04632.7 KFH41137.1 - 4.3 5.6 4.9 5.9 5.1 3.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3560 PF12083.3 KFH41137.1 - 8.3 6.4 8.9 2.4 8.2 2.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3560) Methyltransf_33 PF10017.4 KFH41138.1 - 9.5e-23 80.4 1.2 9.5e-23 80.4 0.9 1.6 2 0 0 2 2 2 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_12 PF08242.7 KFH41138.1 - 0.013 15.9 0.0 0.027 14.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 KFH41139.1 - 3e-19 69.3 0.0 4.1e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH41139.1 - 6.3e-17 61.8 0.0 9.4e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH41139.1 - 2.3e-16 59.7 0.0 2.9e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH41139.1 - 2.4e-15 57.0 0.0 3.6e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH41139.1 - 3.1e-14 53.2 0.0 4.7e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFH41139.1 - 2.7e-10 40.3 0.1 1.3e-09 38.0 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFH41139.1 - 2.3e-06 27.8 0.0 3.5e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFH41139.1 - 2.8e-05 23.3 0.0 3.5e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 KFH41139.1 - 0.00016 20.9 0.0 0.00022 20.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KFH41139.1 - 0.00019 20.5 0.0 0.00027 20.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.6 KFH41139.1 - 0.00076 18.9 0.0 0.001 18.5 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.6 KFH41139.1 - 0.00079 18.2 0.0 0.0012 17.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.9 KFH41139.1 - 0.0022 17.3 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Atx10homo_assoc PF09759.4 KFH41140.1 - 1e-10 41.2 0.0 3.6e-10 39.4 0.0 1.9 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Fapy_DNA_glyco PF01149.19 KFH41141.1 - 1.8e-06 28.2 0.0 2.1e-06 28.0 0.0 1.0 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain PAS_9 PF13426.1 KFH41142.1 - 1.3e-14 54.4 0.0 1.7e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.6 KFH41142.1 - 0.019 15.0 0.1 0.078 13.0 0.0 1.9 2 0 0 2 2 2 0 PAS fold zf-C2H2_4 PF13894.1 KFH41143.1 - 0.0075 16.5 5.5 0.43 11.0 0.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KFH41143.1 - 4.7 7.7 16.1 0.11 12.8 0.7 3.4 3 1 0 3 3 3 0 Zinc finger, C2H2 type Ribosomal_L14 PF00238.14 KFH41145.1 - 2.6e-43 146.6 1.8 2.9e-43 146.4 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e FlgH PF02107.11 KFH41145.1 - 0.044 13.3 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Flagellar L-ring protein DUF4035 PF13227.1 KFH41145.1 - 0.077 12.3 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4035) RGS PF00615.14 KFH41147.1 - 0.039 14.0 0.0 0.14 12.2 0.0 1.9 1 1 0 1 1 1 0 Regulator of G protein signaling domain Phytase PF02333.10 KFH41148.1 - 6.5e-63 212.7 2.1 5.5e-60 203.0 0.1 2.8 2 1 0 3 3 3 2 Phytase EGF_2 PF07974.8 KFH41148.1 - 0.0027 17.8 17.1 0.0027 17.8 11.9 2.5 2 0 0 2 2 2 1 EGF-like domain EGF PF00008.22 KFH41148.1 - 3 7.8 15.9 1.2 9.1 8.4 2.1 2 0 0 2 2 2 0 EGF-like domain TFIIS_C PF01096.13 KFH41149.1 - 4e-16 58.3 4.3 4e-16 58.3 3.0 3.6 4 0 0 4 4 4 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KFH41149.1 - 1.6e-10 40.5 2.4 1.6e-10 40.5 1.7 2.7 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit OrfB_Zn_ribbon PF07282.6 KFH41149.1 - 0.033 13.8 0.9 0.033 13.8 0.6 3.0 2 1 1 3 3 3 0 Putative transposase DNA-binding domain DZR PF12773.2 KFH41149.1 - 0.042 13.6 3.5 0.042 13.6 2.4 3.1 2 1 0 2 2 2 0 Double zinc ribbon GFA PF04828.9 KFH41149.1 - 0.18 11.7 0.1 0.18 11.7 0.1 3.3 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme DUF2296 PF10058.4 KFH41149.1 - 7.5 6.3 16.9 0.97 9.2 0.3 3.7 2 1 1 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) LrgB PF04172.11 KFH41150.1 - 2.9e-12 46.2 9.6 7.1e-07 28.5 0.2 2.9 3 0 0 3 3 3 2 LrgB-like family Arylesterase PF01731.15 KFH41150.1 - 0.049 13.6 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 Arylesterase DUF2360 PF10152.4 KFH41151.1 - 0.091 13.0 0.3 0.14 12.4 0.2 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) zf-B_box PF00643.19 KFH41151.1 - 0.6 10.0 5.1 1.6 8.7 3.5 1.7 1 0 0 1 1 1 0 B-box zinc finger Peptidase_M28 PF04389.12 KFH41153.1 - 1.6e-35 122.4 0.0 3e-35 121.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KFH41153.1 - 1.3e-13 50.5 0.0 2.7e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 PA domain HpcH_HpaI PF03328.9 KFH41154.1 - 6.5e-39 133.0 0.0 7.8e-39 132.8 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family FMN_dh PF01070.13 KFH41155.1 - 1.2e-101 340.0 1.5 3.9e-97 325.2 0.1 2.1 2 0 0 2 2 2 2 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KFH41155.1 - 7.9e-17 60.8 0.0 1.5e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KFH41155.1 - 0.0012 17.8 0.0 0.0021 17.0 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KFH41155.1 - 0.01 14.7 0.2 0.089 11.6 0.0 2.2 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Fungal_trans PF04082.13 KFH41156.1 - 0.0035 16.2 0.0 0.005 15.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH41156.1 - 0.8 9.6 9.0 0.25 11.3 3.9 1.9 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain SET PF00856.23 KFH41157.1 - 1.7e-09 38.2 1.1 6.4e-09 36.3 0.0 2.6 3 1 0 3 3 3 1 SET domain Tmemb_55A PF09788.4 KFH41157.1 - 0.0065 15.6 0.2 0.0065 15.6 0.1 2.4 2 1 1 3 3 3 1 Transmembrane protein 55A Glyco_hydro_43 PF04616.9 KFH41158.1 - 8.9e-74 248.1 1.1 1.2e-73 247.7 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Rotamase PF00639.16 KFH41159.1 - 1.9e-21 76.5 0.0 2.5e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 KFH41159.1 - 1.2e-16 61.0 0.0 1.4e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 KFH41159.1 - 6.6e-08 32.2 0.5 6.6e-08 32.2 0.3 1.6 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.1 KFH41159.1 - 3.6e-06 27.5 0.0 4.8e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain MAM PF00629.18 KFH41159.1 - 0.029 14.1 0.2 0.15 11.7 0.0 1.9 1 1 1 2 2 2 0 MAM domain HAUS-augmin3 PF14932.1 KFH41160.1 - 0.00017 20.8 8.4 0.00025 20.3 0.6 2.9 2 1 0 2 2 2 1 HAUS augmin-like complex subunit 3 Atg14 PF10186.4 KFH41160.1 - 0.013 14.5 5.3 0.17 10.7 0.5 2.6 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF16 PF01519.11 KFH41160.1 - 0.049 13.8 1.1 24 5.2 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function DUF16 BLOC1_2 PF10046.4 KFH41160.1 - 0.2 11.8 2.5 1.3 9.2 0.5 3.1 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TBPIP PF07106.8 KFH41160.1 - 1 8.8 6.8 1.5 8.3 0.9 3.2 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Synaptobrevin PF00957.16 KFH41160.1 - 1.4 8.5 3.6 11 5.6 1.1 3.1 2 1 1 3 3 3 0 Synaptobrevin Spc7 PF08317.6 KFH41160.1 - 2.3 6.7 9.1 0.48 9.0 1.5 2.4 1 1 0 2 2 2 0 Spc7 kinetochore protein Bacillus_HBL PF05791.6 KFH41160.1 - 3.4 6.9 6.1 2.8 7.2 1.0 2.6 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Allexi_40kDa PF05549.6 KFH41160.1 - 5.4 6.2 7.0 8.1 5.6 0.5 2.6 1 1 0 2 2 2 0 Allexivirus 40kDa protein DUF3499 PF12005.3 KFH41160.1 - 6.1 7.0 6.7 20 5.3 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) DUF1664 PF07889.7 KFH41160.1 - 9.2 6.0 9.9 34 4.2 0.7 4.1 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) PALP PF00291.20 KFH41161.1 - 2.4e-51 174.8 0.4 2.9e-51 174.5 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme p450 PF00067.17 KFH41162.1 - 2.6e-49 167.9 0.0 3.7e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 BTB PF00651.26 KFH41163.1 - 0.0068 16.3 0.0 0.066 13.2 0.0 2.4 1 1 0 1 1 1 1 BTB/POZ domain TauD PF02668.11 KFH41164.1 - 1.3e-43 149.5 0.0 1.9e-43 149.0 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family PAP2_3 PF14378.1 KFH41165.1 - 7.2e-21 74.5 7.7 8.3e-16 58.0 1.0 2.4 2 0 0 2 2 2 2 PAP2 superfamily RtcB PF01139.12 KFH41165.1 - 0.024 13.6 0.0 0.034 13.1 0.0 1.1 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB YTH PF04146.10 KFH41167.1 - 2.9e-57 192.1 0.0 4.2e-57 191.6 0.0 1.2 1 0 0 1 1 1 1 YT521-B-like domain RRM_6 PF14259.1 KFH41167.1 - 0.0005 20.0 0.0 0.0017 18.2 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFH41167.1 - 0.00075 19.0 0.0 0.0027 17.2 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cation_efflux PF01545.16 KFH41168.1 - 2.8e-34 118.4 10.0 3.9e-34 118.0 6.9 1.2 1 0 0 1 1 1 1 Cation efflux family DUF4059 PF13268.1 KFH41168.1 - 0.29 11.3 3.1 1.6 8.9 0.1 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF4059) Rad51 PF08423.6 KFH41169.1 - 1.2e-136 453.5 0.0 1.5e-136 453.2 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KFH41169.1 - 7e-13 48.4 0.0 1e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 KFH41169.1 - 1.8e-08 34.3 0.7 5e-08 32.9 0.0 2.1 3 0 0 3 3 3 1 Helix-hairpin-helix domain RecA PF00154.16 KFH41169.1 - 1.7e-06 27.3 0.0 2.4e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 KFH41169.1 - 3.8e-06 26.1 0.0 6.6e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 KaiC DnaB_C PF03796.10 KFH41169.1 - 0.037 12.9 0.0 0.068 12.0 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain HHH PF00633.18 KFH41169.1 - 0.05 13.3 0.1 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif Kelch_5 PF13854.1 KFH41171.1 - 9.5e-17 60.5 3.4 1e-08 34.9 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.1 KFH41171.1 - 1.8e-12 46.8 8.0 0.0056 16.4 0.0 6.2 5 2 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.1 KFH41171.1 - 5.1e-12 45.6 8.0 1.2e-05 25.2 0.0 5.5 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.1 KFH41171.1 - 3.2e-10 39.7 4.4 0.1 12.8 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 KFH41171.1 - 1.2e-05 24.8 4.0 0.015 15.0 0.0 4.3 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 KFH41171.1 - 0.0066 15.9 7.5 0.66 9.5 0.0 4.7 5 0 0 5 5 5 1 Kelch motif HSP20 PF00011.16 KFH41172.1 - 3.9e-18 65.1 0.0 1.8e-13 50.2 0.0 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family Proteasome PF00227.21 KFH41173.1 - 3.4e-28 98.2 0.2 1.4e-27 96.2 0.2 1.8 2 1 0 2 2 2 1 Proteasome subunit Nup160 PF11715.3 KFH41174.1 - 1.8e-118 396.0 0.2 1.7e-117 392.8 0.1 2.0 1 1 0 1 1 1 1 Nucleoporin Nup120/160 DUF2622 PF11080.3 KFH41174.1 - 0.014 15.2 0.0 0.036 13.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2622) Ribosomal_L6 PF00347.18 KFH41175.1 - 3e-24 85.3 9.9 3.6e-13 49.8 3.2 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 PI3_PI4_kinase PF00454.22 KFH41176.1 - 4.7e-40 137.5 0.1 2.2e-39 135.3 0.1 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 KFH41176.1 - 3e-24 85.2 0.0 7e-24 84.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) V-ATPase_H_N PF03224.9 KFH41177.1 - 1e-72 244.9 0.0 1.3e-72 244.5 0.0 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 KFH41177.1 - 1e-37 128.6 0.4 3.3e-37 127.0 0.0 2.1 3 0 0 3 3 3 1 V-ATPase subunit H HEAT_2 PF13646.1 KFH41177.1 - 0.021 15.0 5.2 0.29 11.4 0.0 3.5 3 1 1 4 4 4 0 HEAT repeats HEAT PF02985.17 KFH41177.1 - 0.077 13.1 0.5 1.3 9.3 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.1 KFH41177.1 - 0.17 12.4 3.9 8.5 7.0 0.0 3.9 2 2 1 3 3 3 0 HEAT-like repeat Rhomboid_SP PF12595.3 KFH41178.1 - 0.11 12.0 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Rhomboid serine protease SDA1 PF05285.7 KFH41179.1 - 0.0037 16.6 6.6 0.0037 16.6 4.6 2.9 3 0 0 3 3 3 1 SDA1 HATPase_c_3 PF13589.1 KFH41180.1 - 1.7e-14 53.6 0.5 4.1e-14 52.3 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 KFH41180.1 - 5.3e-10 38.7 0.0 9.8e-10 37.9 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.21 KFH41180.1 - 2.4e-09 36.8 0.1 5.2e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Metallophos PF00149.23 KFH41182.1 - 3e-10 39.8 1.2 1e-09 38.0 0.8 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase GCV_T PF01571.16 KFH41183.1 - 5.8e-58 195.7 0.0 7.8e-58 195.3 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KFH41183.1 - 4e-23 81.2 1.7 8.7e-23 80.1 1.2 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain TrmE_N PF10396.4 KFH41183.1 - 0.0018 18.2 0.0 0.33 10.9 0.0 2.4 2 0 0 2 2 2 2 GTP-binding protein TrmE N-terminus Glycophorin_A PF01102.13 KFH41184.1 - 0.026 14.2 0.4 0.17 11.6 0.2 2.1 2 0 0 2 2 2 0 Glycophorin A DUF4131 PF13567.1 KFH41184.1 - 0.051 12.9 0.2 0.55 9.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Vps26 PF03643.10 KFH41185.1 - 1.2e-129 431.0 0.6 1.4e-129 430.7 0.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 KFH41185.1 - 0.0013 18.6 0.1 0.51 10.1 0.0 3.4 1 1 1 2 2 2 1 Arrestin (or S-antigen), N-terminal domain zf-DHHC PF01529.15 KFH41186.1 - 2.4e-33 114.9 0.7 2.4e-33 114.9 0.5 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase Lyase_aromatic PF00221.14 KFH41187.1 - 5.7e-158 526.2 5.5 7.5e-158 525.8 3.8 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase Pribosyltran_N PF13793.1 KFH41188.1 - 9.9e-44 147.7 0.1 1.1e-41 141.1 0.0 2.4 2 1 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KFH41188.1 - 2.1e-34 118.8 0.2 8.2e-28 97.3 0.0 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KFH41188.1 - 2.6e-09 36.8 0.0 6.1e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain MORN PF02493.15 KFH41189.1 - 0.1 12.3 2.4 1.5 8.7 0.2 3.1 2 0 0 2 2 2 0 MORN repeat CENP-B_dimeris PF09026.5 KFH41189.1 - 0.9 9.8 9.3 0.083 13.1 3.0 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain APG12 PF04110.8 KFH41191.1 - 2.3e-26 91.7 0.0 3.2e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 KFH41191.1 - 0.0013 18.7 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Peptidase_M24 PF00557.19 KFH41192.1 - 2.5e-49 167.6 0.0 4.3e-49 166.9 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KFH41192.1 - 4.7e-34 116.6 0.0 9.1e-34 115.7 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Dfp1_Him1_M PF08630.5 KFH41194.1 - 1.7e-39 134.4 0.0 4e-39 133.2 0.0 1.7 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 KFH41194.1 - 1.5e-23 82.2 0.6 2.4e-23 81.5 0.4 1.3 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.21 KFH41194.1 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KFH41194.1 - 0.14 11.9 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain LysM PF01476.15 KFH41195.1 - 0.019 14.8 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 LysM domain Adeno_E1A PF02703.9 KFH41195.1 - 0.72 9.2 4.8 0.87 8.9 2.7 1.4 1 1 1 2 2 2 0 Early E1A protein Rap1_C PF11626.3 KFH41196.1 - 1.4e-21 76.1 0.1 2.9e-21 75.1 0.1 1.6 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 KFH41196.1 - 2.8e-16 59.0 0.1 6.1e-16 57.9 0.1 1.6 1 0 0 1 1 1 1 Rap1 Myb domain ARID PF01388.16 KFH41196.1 - 4e-10 39.4 0.0 1e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Rap1-DNA-bind PF09197.5 KFH41196.1 - 0.00046 20.7 0.3 0.0017 18.8 0.0 2.1 2 0 0 2 2 2 1 Rap1, DNA-binding DUF58 PF01882.13 KFH41196.1 - 0.058 13.5 0.1 0.62 10.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF58 DUF572 PF04502.8 KFH41197.1 - 3.1e-44 151.5 0.0 5.1e-44 150.8 0.0 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF572) SR-25 PF10500.4 KFH41197.1 - 0.094 12.1 3.1 0.18 11.2 2.1 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FlgN PF05130.7 KFH41197.1 - 0.16 12.2 0.8 0.28 11.4 0.6 1.3 1 0 0 1 1 1 0 FlgN protein Atrophin-1 PF03154.10 KFH41197.1 - 2 6.4 12.7 0.038 12.1 3.8 1.6 2 0 0 2 2 2 0 Atrophin-1 family Mito_fiss_reg PF05308.6 KFH41197.1 - 5.8 6.2 11.7 0.36 10.1 4.7 1.4 2 0 0 2 2 2 0 Mitochondrial fission regulator Flavoprotein PF02441.14 KFH41201.1 - 4.6e-14 52.2 0.0 9e-14 51.2 0.0 1.5 1 0 0 1 1 1 1 Flavoprotein Sec7_N PF12783.2 KFH41202.1 - 4.6e-37 127.0 2.4 1.6e-35 121.9 0.0 3.2 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KFH41202.1 - 0.00018 20.9 2.4 0.0021 17.5 0.0 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) Band_7 PF01145.20 KFH41203.1 - 2.2e-31 109.1 0.4 3.8e-31 108.3 0.3 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 KFH41203.1 - 0.035 13.6 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family Tht1 PF04163.7 KFH41204.1 - 5.1e-07 28.4 0.2 1.4e-06 27.0 0.1 1.6 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein Selenoprotein_S PF06936.6 KFH41204.1 - 0.0081 15.7 0.4 0.015 14.8 0.3 1.5 1 0 0 1 1 1 1 Selenoprotein S (SelS) IL6 PF00489.12 KFH41204.1 - 0.042 13.4 0.2 0.39 10.3 0.0 2.4 1 1 0 2 2 2 0 Interleukin-6/G-CSF/MGF family Hormone_1 PF00103.15 KFH41204.1 - 0.05 12.9 4.6 1.7 7.8 0.1 2.9 1 1 2 3 3 3 0 Somatotropin hormone family Cortex-I_coil PF09304.5 KFH41204.1 - 0.4 10.7 4.5 3.7 7.6 0.6 2.5 2 0 0 2 2 2 0 Cortexillin I, coiled coil DUF3450 PF11932.3 KFH41204.1 - 0.65 9.2 11.4 0.098 11.9 3.8 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) Syntaxin PF00804.20 KFH41204.1 - 0.72 10.0 6.3 2.7 8.1 0.4 2.6 1 1 1 2 2 2 0 Syntaxin Baculo_PEP_C PF04513.7 KFH41204.1 - 1.3 8.8 6.3 0.48 10.2 0.2 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.2 KFH41204.1 - 4.8 7.0 10.6 31 4.4 0.2 2.5 1 1 1 2 2 2 0 Tropomyosin like Pantoate_transf PF02548.10 KFH41205.1 - 5.6e-101 337.0 0.1 6.6e-101 336.8 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 KFH41205.1 - 5.1e-09 35.6 0.0 8.3e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase UQ_con PF00179.21 KFH41206.1 - 4.9e-16 58.4 0.0 5.4e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KFH41206.1 - 0.0081 16.0 0.0 0.0088 15.9 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KFH41206.1 - 0.026 14.2 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 UEV domain Aha1_N PF09229.6 KFH41207.1 - 5e-33 113.8 0.5 1.1e-31 109.4 0.3 2.3 1 1 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 KFH41207.1 - 8.8e-17 61.3 0.3 2.2e-16 60.0 0.2 1.7 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 KFH41207.1 - 0.021 15.0 2.9 0.021 14.9 0.4 2.0 2 0 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport DnaJ PF00226.26 KFH41207.1 - 0.09 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 DnaJ domain UQ_con PF00179.21 KFH41208.1 - 2.6e-33 114.4 0.0 3.6e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Glyco_hydro_20 PF00728.17 KFH41210.1 - 3.6e-36 125.0 4.0 2.1e-35 122.5 2.8 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.10 KFH41210.1 - 1.3e-07 32.1 0.0 3.3e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 BetaGal_dom4_5 PF13364.1 KFH41210.1 - 0.35 11.1 3.0 1.1 9.6 0.0 2.7 3 0 0 3 3 3 0 Beta-galactosidase jelly roll domain Complex1_LYR PF05347.10 KFH41211.1 - 2.7e-07 30.2 2.4 9.3e-07 28.5 1.7 2.0 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KFH41211.1 - 4.3e-06 26.8 4.7 1.3e-05 25.2 3.3 2.0 1 1 0 1 1 1 1 Complex1_LYR-like Con-6 PF10346.4 KFH41212.1 - 1.4e-12 46.7 0.2 2.3e-12 46.0 0.2 1.4 1 0 0 1 1 1 1 Conidiation protein 6 CENP-L PF13092.1 KFH41213.1 - 6.3e-49 165.8 0.0 1.5e-47 161.3 0.0 2.1 2 0 0 2 2 2 2 Kinetochore complex Sim4 subunit Fta1 Abhydrolase_5 PF12695.2 KFH41214.1 - 9.6e-05 22.1 0.0 0.00015 21.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFH41214.1 - 0.00047 20.1 0.1 0.00096 19.0 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.5 KFH41214.1 - 0.0092 14.9 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Lipase_3 PF01764.20 KFH41214.1 - 0.092 12.3 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase2 PF12740.2 KFH41214.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.6 KFH41214.1 - 0.14 10.9 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase UDPG_MGDP_dh_N PF03721.9 KFH41215.1 - 1.4e-47 161.4 0.0 6.8e-29 100.5 0.0 2.2 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 KFH41215.1 - 1.9e-31 108.0 0.0 3.9e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 KFH41215.1 - 7.3e-24 83.9 0.0 1.9e-18 66.5 0.0 3.2 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_Gly3P_dh_N PF01210.18 KFH41215.1 - 0.0029 17.3 0.0 2.1 8.0 0.0 3.3 3 0 0 3 3 3 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Saccharop_dh PF03435.13 KFH41215.1 - 0.0037 16.2 0.0 0.0057 15.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_2 PF03446.10 KFH41215.1 - 0.0081 16.0 0.0 3.3 7.5 0.0 2.5 2 0 0 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 KFH41215.1 - 0.069 12.8 0.0 0.16 11.6 0.0 1.7 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Acetyltransf_1 PF00583.19 KFH41217.1 - 4.3e-16 58.7 0.0 1.3e-15 57.2 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KFH41217.1 - 2.4e-09 36.8 0.0 3.7e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KFH41217.1 - 4.9e-07 29.8 0.0 8.1e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KFH41217.1 - 1.5e-05 25.1 0.0 3.1e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFH41217.1 - 1.5e-05 25.0 0.0 2.9e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFH41217.1 - 0.023 14.5 0.0 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KFH41217.1 - 0.033 14.1 0.0 0.5 10.3 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 KFH41217.1 - 0.041 13.4 0.0 0.084 12.4 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KFH41217.1 - 0.15 12.0 0.0 0.5 10.3 0.0 1.8 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase EthD PF07110.6 KFH41218.1 - 4.6e-25 88.3 0.2 5.7e-25 88.0 0.2 1.1 1 0 0 1 1 1 1 EthD domain Glycos_transf_1 PF00534.15 KFH41220.1 - 5.8e-34 116.9 0.0 8.5e-34 116.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KFH41220.1 - 4.2e-18 65.7 0.0 8.4e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KFH41220.1 - 4.5e-11 43.1 0.1 9.2e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 KFH41220.1 - 1.3e-10 41.4 0.0 5e-10 39.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KFH41220.1 - 9.9e-06 25.3 0.1 8.2e-05 22.3 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase Family 4 GlgS PF08971.6 KFH41220.1 - 0.054 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Glycogen synthesis protein DUF485 PF04341.7 KFH41220.1 - 0.17 11.6 0.3 0.33 10.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF485 NAD_binding_10 PF13460.1 KFH41221.1 - 2.9e-05 24.1 0.3 5.5e-05 23.2 0.2 1.8 1 1 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 KFH41221.1 - 0.003 17.4 0.3 0.0058 16.5 0.2 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.8 KFH41221.1 - 0.021 14.0 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family NAD_binding_4 PF07993.7 KFH41221.1 - 0.033 13.1 0.0 0.2 10.5 0.0 2.0 2 0 0 2 2 2 0 Male sterility protein adh_short PF00106.20 KFH41221.1 - 0.15 11.9 0.8 0.25 11.2 0.5 1.5 1 1 0 1 1 1 0 short chain dehydrogenase Ank_4 PF13637.1 KFH41222.1 - 1e-13 51.3 1.7 3.3e-07 30.6 0.1 3.8 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KFH41222.1 - 4.5e-13 49.3 0.1 8.8e-09 35.5 0.0 3.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFH41222.1 - 3.6e-11 42.2 3.8 0.00015 21.4 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.1 KFH41222.1 - 7.3e-11 41.2 0.1 0.0023 18.0 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 KFH41222.1 - 3.8e-10 39.6 0.4 0.00077 19.6 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) KilA-N PF04383.8 KFH41222.1 - 0.00017 21.1 0.6 0.0011 18.5 0.2 2.4 2 1 0 2 2 2 1 KilA-N domain KaiC PF06745.8 KFH41222.1 - 0.051 12.6 0.8 0.1 11.6 0.6 1.4 1 0 0 1 1 1 0 KaiC Prp18 PF02840.10 KFH41222.1 - 0.063 13.1 2.7 0.13 12.1 1.7 1.6 2 0 0 2 2 2 0 Prp18 domain Med2 PF11214.3 KFH41222.1 - 0.1 12.6 0.9 0.24 11.4 0.6 1.6 1 0 0 1 1 1 0 Mediator complex subunit 2 Filament PF00038.16 KFH41222.1 - 1 8.7 7.9 0.75 9.1 4.1 1.7 2 0 0 2 2 2 0 Intermediate filament protein MFS_1 PF07690.11 KFH41223.1 - 1.8e-19 69.6 31.5 2.5e-12 46.1 11.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH41223.1 - 2.8e-17 62.4 15.6 5e-17 61.6 10.8 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter 5_nucleotid_C PF02872.13 KFH41225.1 - 5.3e-38 130.4 0.0 8.3e-38 129.8 0.0 1.2 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain FYVE PF01363.16 KFH41227.1 - 8.4e-25 86.4 20.6 8.9e-18 63.9 3.8 3.2 3 0 0 3 3 3 2 FYVE zinc finger zf-AN1 PF01428.11 KFH41227.1 - 0.00066 19.5 3.1 0.00066 19.5 2.2 3.5 3 1 0 3 3 3 1 AN1-like Zinc finger Rbsn PF11464.3 KFH41227.1 - 0.012 15.2 3.3 0.015 14.8 0.2 2.5 2 0 0 2 2 2 0 Rabenosyn Rab binding domain zf-Di19 PF05605.7 KFH41227.1 - 0.018 15.1 0.1 0.018 15.1 0.1 3.1 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-NADH-PPase PF09297.6 KFH41227.1 - 0.026 14.0 5.8 0.43 10.1 0.1 3.9 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain IBR PF01485.16 KFH41227.1 - 0.037 13.8 0.7 0.037 13.8 0.5 3.5 4 1 0 4 4 4 0 IBR domain zf-C2H2_2 PF12756.2 KFH41227.1 - 0.62 10.2 0.0 0.62 10.2 0.0 3.2 4 0 0 4 4 3 0 C2H2 type zinc-finger (2 copies) TMF_TATA_bd PF12325.3 KFH41227.1 - 4.7 6.9 13.2 0.044 13.5 2.1 2.6 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding zf-C2HC5 PF06221.8 KFH41227.1 - 7.3 6.4 20.0 0.47 10.2 0.5 4.3 4 1 1 5 5 5 0 Putative zinc finger motif, C2HC5-type DZR PF12773.2 KFH41227.1 - 8 6.3 21.1 4.8 7.0 1.1 4.9 4 1 1 5 5 5 0 Double zinc ribbon TMF_DNA_bd PF12329.3 KFH41227.1 - 8.2 6.3 8.2 7.1 6.5 0.3 3.1 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding ADH_zinc_N PF00107.21 KFH41228.1 - 1.8e-25 88.9 0.2 3e-25 88.2 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFH41228.1 - 2.5e-14 54.2 0.3 6.1e-14 53.0 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFH41228.1 - 1.7e-11 43.8 0.0 3.7e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 KFH41228.1 - 0.0032 17.0 0.2 0.0056 16.2 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_kinase PF01513.16 KFH41228.1 - 0.017 13.8 0.2 0.039 12.7 0.0 1.6 2 0 0 2 2 2 0 ATP-NAD kinase DAGK_cat PF00781.19 KFH41228.1 - 0.026 13.9 0.8 0.27 10.6 0.0 2.9 4 0 0 4 4 4 0 Diacylglycerol kinase catalytic domain ELFV_dehydrog PF00208.16 KFH41228.1 - 0.071 12.6 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Dehydratase_hem PF13816.1 KFH41229.1 - 4.4e-100 334.7 0.4 5.1e-100 334.5 0.3 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.1 KFH41229.1 - 1.3e-08 34.9 0.3 4.4e-05 23.5 0.2 3.1 3 1 0 3 3 3 2 Domain of unknown function (DUF4188) S1FA PF04689.8 KFH41230.1 - 5.2 7.0 5.9 14 5.6 0.5 2.4 2 0 0 2 2 2 0 DNA binding protein S1FA NAD_binding_7 PF13241.1 KFH41231.1 - 8.8e-33 112.6 0.0 1.9e-32 111.5 0.0 1.5 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 KFH41231.1 - 1.2e-26 91.8 0.0 1.8e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 KFH41231.1 - 2e-15 55.4 0.1 3.1e-15 54.8 0.1 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.1 KFH41231.1 - 0.015 15.4 0.1 0.24 11.4 0.0 2.1 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 KFH41231.1 - 0.033 14.0 0.7 0.059 13.1 0.0 1.8 1 1 1 2 2 2 0 ThiF family TrkA_N PF02254.13 KFH41231.1 - 0.05 13.6 0.1 0.084 12.8 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.15 KFH41231.1 - 0.14 12.2 0.3 0.28 11.2 0.2 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.16 KFH41231.1 - 0.15 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Prenyltrans PF00432.16 KFH41232.1 - 7.1e-34 115.0 26.6 9.4e-08 31.4 0.6 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KFH41232.1 - 4e-22 78.7 0.0 8.6e-15 55.1 0.0 3.9 2 1 2 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KFH41232.1 - 1.4e-06 28.2 0.0 3.8e-05 23.6 0.0 2.9 3 1 0 3 3 3 1 Prenyltransferase-like DND1_DSRM PF14709.1 KFH41233.1 - 0.00018 21.7 0.1 0.00035 20.7 0.0 1.5 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.20 KFH41233.1 - 0.008 16.7 0.0 0.017 15.6 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif DUF755 PF05501.6 KFH41233.1 - 0.62 10.1 10.6 0.83 9.7 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Acyltransferase PF01553.16 KFH41235.1 - 4.2e-11 42.4 0.0 1.4e-05 24.5 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase VHS PF00790.14 KFH41236.1 - 5.8e-41 139.4 4.6 8.8e-41 138.8 0.1 2.3 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 KFH41236.1 - 9.8e-16 57.4 5.3 2e-15 56.4 3.6 1.5 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 KFH41236.1 - 0.00027 20.2 14.3 0.021 14.3 0.3 3.4 3 0 0 3 3 3 2 Ubiquitin interaction motif zf-DHHC PF01529.15 KFH41236.1 - 0.00076 18.9 1.2 0.00076 18.9 0.9 3.1 2 1 0 2 2 2 1 DHHC palmitoyltransferase FYVE_2 PF02318.11 KFH41236.1 - 0.042 13.7 2.0 0.091 12.6 1.4 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Ribosomal_S30AE PF02482.14 KFH41236.1 - 0.25 11.7 2.7 0.9 10.0 1.9 1.9 1 0 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein AMP-binding PF00501.23 KFH41237.1 - 6.4e-77 258.6 0.0 8.7e-77 258.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme zf-UBP PF02148.14 KFH41238.1 - 6.3e-20 71.0 6.2 1.4e-19 69.9 4.3 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein BRAP2 PF07576.7 KFH41238.1 - 7.5e-20 70.5 0.0 1.3e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-RING_2 PF13639.1 KFH41238.1 - 2.1e-10 40.2 9.8 2.1e-10 40.2 6.8 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KFH41238.1 - 5.8e-06 25.8 8.0 5.8e-06 25.8 5.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFH41238.1 - 6.5e-06 25.7 7.5 6.5e-06 25.7 5.2 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFH41238.1 - 2e-05 24.1 18.1 0.00017 21.1 5.1 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFH41238.1 - 0.00041 20.3 9.3 0.00041 20.3 6.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFH41238.1 - 0.0061 16.6 5.2 0.0061 16.6 3.6 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger Exonuc_VII_L PF02601.10 KFH41238.1 - 0.0072 15.5 7.6 0.014 14.5 5.3 1.4 1 0 0 1 1 1 1 Exonuclease VII, large subunit zf-RING_UBOX PF13445.1 KFH41238.1 - 0.013 15.1 5.3 0.013 15.1 3.7 2.8 2 1 0 2 2 2 0 RING-type zinc-finger Cor1 PF04803.7 KFH41238.1 - 0.016 14.9 4.9 0.026 14.2 3.4 1.4 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region zf-Apc11 PF12861.2 KFH41238.1 - 0.093 12.5 6.0 0.25 11.2 4.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Usp PF00582.21 KFH41238.1 - 0.27 11.4 3.5 0.58 10.3 2.4 1.6 1 0 0 1 1 1 0 Universal stress protein family COG5 PF10392.4 KFH41238.1 - 0.37 10.7 5.6 0.72 9.8 3.9 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 zf-RING_4 PF14570.1 KFH41238.1 - 0.54 9.8 6.9 1.3 8.6 4.8 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF465 PF04325.8 KFH41238.1 - 0.55 9.9 5.0 0.3 10.7 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF465) DivIC PF04977.10 KFH41238.1 - 3.5 7.1 6.2 0.63 9.5 0.9 2.3 1 1 1 2 2 2 0 Septum formation initiator Baculo_RING PF05883.6 KFH41238.1 - 4 7.2 5.1 1.3 8.8 1.1 2.0 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain zf-RING_6 PF14835.1 KFH41238.1 - 4.4 7.1 11.9 0.035 13.8 2.4 1.8 2 0 0 2 2 1 0 zf-RING of BARD1-type protein Glyco_hydro_28 PF00295.12 KFH41239.1 - 1.2e-32 113.1 0.6 2.1e-32 112.3 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 SnoaL PF07366.7 KFH41239.1 - 0.082 12.5 0.8 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase Beta_helix PF13229.1 KFH41239.1 - 0.55 9.9 13.7 2.9 7.6 9.5 2.2 1 1 0 1 1 1 0 Right handed beta helix region Suc_Fer-like PF06999.7 KFH41241.1 - 2.4e-32 112.7 0.0 3.8e-32 112.1 0.0 1.3 1 1 0 1 1 1 1 Sucrase/ferredoxin-like His_Phos_1 PF00300.17 KFH41242.1 - 1.6e-15 57.5 0.0 1.4e-14 54.5 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) UCH PF00443.24 KFH41243.1 - 1.8e-35 122.3 0.0 2.8e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFH41243.1 - 1.2e-15 57.8 0.0 4.6e-15 55.8 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 KFH41243.1 - 1.1e-05 25.7 0.0 2.3e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Hemerythrin PF01814.18 KFH41243.1 - 0.092 12.9 0.0 2.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain Zn_clus PF00172.13 KFH41245.1 - 0.0034 17.2 7.7 0.007 16.2 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FGGY_C PF02782.11 KFH41246.1 - 7.6e-70 234.5 2.8 1.1e-69 234.0 1.5 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KFH41246.1 - 3.3e-62 209.9 0.0 4.9e-62 209.4 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Cupin_2 PF07883.6 KFH41247.1 - 1.8e-06 27.3 0.2 1.8e-06 27.3 0.1 1.6 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.17 KFH41247.1 - 3.6e-06 26.4 0.0 5.6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.2 KFH41247.1 - 0.01 15.4 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 0 Cupin Cupin_3 PF05899.7 KFH41247.1 - 0.016 14.5 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) PalH PF08733.5 KFH41248.1 - 2.3e-101 339.1 0.0 2.8e-101 338.8 0.0 1.1 1 0 0 1 1 1 1 PalH/RIM21 DUF1771 PF08590.5 KFH41249.1 - 6.2e-22 77.3 10.0 6.2e-22 77.3 6.9 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF1771) Smr PF01713.16 KFH41249.1 - 4.7e-14 52.3 0.4 1.7e-13 50.5 0.3 2.0 1 0 0 1 1 1 1 Smr domain DUF3526 PF12040.3 KFH41249.1 - 0.1 12.7 0.5 0.1 12.7 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3526) BAF1_ABF1 PF04684.8 KFH41249.1 - 1.3 7.7 14.0 2.4 6.8 9.7 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TRAM_LAG1_CLN8 PF03798.11 KFH41250.1 - 8.9e-35 120.0 17.6 8.9e-35 120.0 12.2 1.5 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 KFH41250.1 - 2e-23 81.6 1.1 2.4e-22 78.2 0.0 2.5 2 0 0 2 2 2 1 TRAM1-like protein T_cell_tran_alt PF15128.1 KFH41250.1 - 2.2 7.8 4.4 1.5 8.3 1.1 2.3 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AAA PF00004.24 KFH41251.1 - 6.7e-98 324.0 0.0 9e-48 161.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 KFH41251.1 - 1e-19 70.2 0.9 3.2e-19 68.6 0.3 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 KFH41251.1 - 7.9e-14 51.9 0.0 1.8e-07 31.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KFH41251.1 - 1.2e-13 50.7 0.0 3.4e-06 26.2 0.0 2.9 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KFH41251.1 - 7.4e-13 48.5 0.0 1.5e-05 24.8 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.9 KFH41251.1 - 8.8e-13 48.1 0.5 9.3e-07 28.6 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KFH41251.1 - 6.4e-12 45.7 0.2 0.00067 19.8 0.1 4.1 2 2 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KFH41251.1 - 6.3e-11 43.1 0.0 0.00033 21.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KFH41251.1 - 7e-11 42.4 0.0 0.0003 20.8 0.0 3.8 2 2 1 3 3 3 2 AAA ATPase domain TIP49 PF06068.8 KFH41251.1 - 2.9e-09 36.1 0.1 0.00085 18.1 0.0 2.6 2 0 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 KFH41251.1 - 9.8e-09 34.8 5.4 0.03 13.7 0.0 4.6 2 2 2 4 4 4 3 AAA domain IstB_IS21 PF01695.12 KFH41251.1 - 1.9e-08 33.9 0.0 0.0033 16.8 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 KFH41251.1 - 3.2e-08 33.1 0.9 0.013 15.2 0.0 3.0 3 0 0 3 3 2 2 Part of AAA domain AAA_14 PF13173.1 KFH41251.1 - 3.9e-08 33.2 0.0 0.0014 18.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.16 KFH41251.1 - 1.7e-07 30.5 0.3 0.006 15.7 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 KFH41251.1 - 1.8e-07 30.4 0.1 0.011 14.8 0.0 2.7 3 0 0 3 3 2 2 Zeta toxin CDC48_2 PF02933.12 KFH41251.1 - 2.1e-07 30.4 0.3 6.6e-07 28.8 0.0 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), domain 2 AAA_18 PF13238.1 KFH41251.1 - 1.2e-06 28.8 0.0 0.069 13.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 KFH41251.1 - 1.3e-06 28.4 0.0 0.076 13.1 0.0 2.9 3 0 0 3 3 2 2 RNA helicase KaiC PF06745.8 KFH41251.1 - 1.7e-06 27.2 0.9 0.22 10.5 0.0 3.5 2 1 1 3 3 3 2 KaiC AAA_28 PF13521.1 KFH41251.1 - 2.8e-06 27.4 0.0 0.072 13.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 KFH41251.1 - 3.6e-06 26.9 0.0 0.0021 17.9 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.1 KFH41251.1 - 9.2e-06 25.7 0.0 0.044 13.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.1 KFH41251.1 - 1.2e-05 24.9 0.1 0.14 11.7 0.0 3.1 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.21 KFH41251.1 - 2e-05 24.1 0.1 0.16 11.4 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain DUF815 PF05673.8 KFH41251.1 - 2e-05 23.6 0.0 0.058 12.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) ABC_tran PF00005.22 KFH41251.1 - 2e-05 24.9 0.0 0.23 11.7 0.0 3.4 2 1 0 2 2 2 2 ABC transporter Parvo_NS1 PF01057.12 KFH41251.1 - 2.9e-05 23.0 0.0 0.17 10.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NACHT PF05729.7 KFH41251.1 - 3.7e-05 23.4 0.1 0.2 11.2 0.0 3.2 3 0 0 3 3 3 1 NACHT domain Arch_ATPase PF01637.13 KFH41251.1 - 4.3e-05 23.3 0.1 4 7.0 0.0 3.9 2 2 2 4 4 4 0 Archaeal ATPase PhoH PF02562.11 KFH41251.1 - 7.4e-05 22.0 0.2 0.29 10.3 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_30 PF13604.1 KFH41251.1 - 0.00018 21.1 0.0 0.46 10.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.6 KFH41251.1 - 0.00019 21.0 0.0 0.57 9.7 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.13 KFH41251.1 - 0.0003 20.5 0.0 0.23 11.0 0.0 2.6 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_11 PF13086.1 KFH41251.1 - 0.00075 19.1 0.0 0.82 9.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain NTPase_1 PF03266.10 KFH41251.1 - 0.00081 19.1 0.3 0.66 9.6 0.0 3.8 3 0 0 3 3 3 1 NTPase Vps4_C PF09336.5 KFH41251.1 - 0.00086 19.1 0.2 0.0042 16.9 0.1 2.2 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain NB-ARC PF00931.17 KFH41251.1 - 0.0014 17.5 0.1 1.5 7.5 0.0 2.7 3 0 0 3 3 3 2 NB-ARC domain DUF2075 PF09848.4 KFH41251.1 - 0.0035 16.3 0.0 1.5 7.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 KFH41251.1 - 0.0063 16.0 0.0 0.25 10.8 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.9 KFH41251.1 - 0.0089 15.0 0.3 1.1 8.2 0.0 3.2 2 2 1 3 3 3 1 KAP family P-loop domain IPT PF01745.11 KFH41251.1 - 0.01 14.9 0.0 1.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase AAA_10 PF12846.2 KFH41251.1 - 0.012 15.0 0.8 0.54 9.6 0.0 3.4 3 1 1 4 4 4 0 AAA-like domain UPF0079 PF02367.12 KFH41251.1 - 0.033 13.7 0.1 9 5.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 KFH41251.1 - 0.053 12.4 0.0 2.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein KTI12 PF08433.5 KFH41251.1 - 0.054 12.6 0.4 5.7 6.0 0.0 2.9 3 0 0 3 3 3 0 Chromatin associated protein KTI12 AFG1_ATPase PF03969.11 KFH41251.1 - 0.092 11.5 0.0 11 4.7 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase SKI PF01202.17 KFH41251.1 - 0.096 12.5 0.1 8.3 6.2 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase MobB PF03205.9 KFH41251.1 - 0.12 12.0 1.2 2.8 7.6 0.0 3.2 4 0 0 4 4 3 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 KFH41251.1 - 0.13 11.7 0.0 4.8 6.6 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Dscam_C PF12355.3 KFH41252.1 - 0.14 12.3 0.8 0.16 12.2 0.6 1.1 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal CDC27 PF09507.5 KFH41253.1 - 0.0024 17.1 1.5 0.003 16.8 1.0 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 SR-25 PF10500.4 KFH41253.1 - 0.015 14.7 4.8 0.02 14.3 3.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.4 KFH41253.1 - 0.13 10.5 3.1 0.12 10.6 2.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Period_C PF12114.3 KFH41253.1 - 2 7.9 11.1 2.7 7.5 7.7 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DUF515 PF04415.7 KFH41253.1 - 2.8 6.0 11.5 3.3 5.8 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) KTI12 PF08433.5 KFH41254.1 - 4.5e-70 235.9 0.0 8.7e-70 235.0 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 KFH41254.1 - 2.3e-06 28.4 0.3 3.4e-06 27.8 0.2 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFH41254.1 - 1e-05 25.4 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFH41254.1 - 1.3e-05 25.5 0.0 5.5e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KFH41254.1 - 0.0046 16.8 0.0 0.011 15.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain 6PF2K PF01591.13 KFH41254.1 - 0.0086 15.1 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_16 PF13191.1 KFH41254.1 - 0.018 15.0 0.1 0.052 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 KFH41254.1 - 0.075 13.1 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KFH41254.1 - 0.17 11.5 0.0 0.42 10.3 0.0 1.6 1 0 0 1 1 1 0 NTPase DUF2207 PF09972.4 KFH41255.1 - 4.8 5.6 5.2 9.6 4.6 0.0 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) YjeF_N PF03853.10 KFH41256.1 - 1.1e-36 126.0 0.0 2e-36 125.1 0.0 1.5 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 KFH41256.1 - 6.7e-08 33.0 1.9 6.7e-08 33.0 1.3 2.7 2 0 0 2 2 2 1 FDF domain ABC_tran PF00005.22 KFH41257.1 - 7.6e-34 116.9 0.0 1.8e-33 115.7 0.0 1.7 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 KFH41257.1 - 7.9e-17 61.5 7.1 7.9e-17 61.5 4.9 1.8 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 KFH41257.1 - 5.1e-05 22.6 0.0 0.00026 20.2 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 KFH41257.1 - 0.0053 15.9 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 KFH41257.1 - 0.02 14.8 0.1 0.45 10.4 0.1 3.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 KFH41257.1 - 0.021 14.7 0.0 11 5.9 0.0 2.6 1 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KFH41257.1 - 0.023 14.2 0.1 0.061 12.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KFH41257.1 - 0.026 14.6 0.1 0.12 12.4 0.1 2.1 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.9 KFH41258.1 - 2.4e-60 204.4 0.0 2.2e-46 158.5 0.0 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 KFH41258.1 - 1.5e-16 60.5 0.0 3.1e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KFH41258.1 - 1.6e-07 31.4 0.0 3.4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFH41258.1 - 1.1e-06 28.2 0.1 3e-06 26.8 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain Herpes_Helicase PF02689.9 KFH41258.1 - 1.8e-05 22.7 0.0 6.9e-05 20.8 0.0 1.7 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.1 KFH41258.1 - 2e-05 24.6 0.0 0.0001 22.3 0.0 2.2 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain T2SE PF00437.15 KFH41258.1 - 5e-05 22.3 0.0 8.7e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.24 KFH41258.1 - 0.00023 21.3 0.0 0.00049 20.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFH41258.1 - 0.0003 20.8 0.0 0.00079 19.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.1 KFH41258.1 - 0.00035 20.2 0.1 0.0075 15.8 0.0 2.6 1 1 1 2 2 2 1 AAA domain PhoH PF02562.11 KFH41258.1 - 0.0014 17.8 0.0 0.0037 16.5 0.0 1.7 1 0 0 1 1 1 1 PhoH-like protein ABC_tran PF00005.22 KFH41258.1 - 0.0029 17.9 0.0 0.0081 16.4 0.0 1.7 1 0 0 1 1 1 1 ABC transporter NACHT PF05729.7 KFH41258.1 - 0.0034 17.0 0.0 0.013 15.2 0.0 1.9 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 KFH41258.1 - 0.0038 17.3 0.0 0.009 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase DUF2075 PF09848.4 KFH41258.1 - 0.0067 15.4 0.0 0.018 13.9 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 KFH41258.1 - 0.009 15.9 0.0 0.028 14.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KFH41258.1 - 0.014 14.8 0.0 0.21 10.9 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.2 KFH41258.1 - 0.015 14.3 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 Arch_ATPase PF01637.13 KFH41258.1 - 0.015 14.9 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_10 PF12846.2 KFH41258.1 - 0.017 14.5 0.0 0.29 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain Sigma54_activat PF00158.21 KFH41258.1 - 0.021 14.3 0.0 0.061 12.8 0.0 1.8 1 1 1 2 2 2 0 Sigma-54 interaction domain Viral_helicase1 PF01443.13 KFH41258.1 - 0.022 14.2 0.0 0.55 9.7 0.0 2.5 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.1 KFH41258.1 - 0.025 14.0 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.1 KFH41258.1 - 0.034 14.2 0.0 0.087 12.8 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 KFH41258.1 - 0.047 12.8 0.0 0.076 12.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 KFH41258.1 - 0.057 12.6 0.0 0.098 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 TrwB_AAD_bind PF10412.4 KFH41258.1 - 0.067 11.7 0.0 0.19 10.2 0.0 1.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain MobB PF03205.9 KFH41258.1 - 0.079 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ResIII PF04851.10 KFH41258.1 - 0.092 12.5 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.12 KFH41258.1 - 0.11 11.2 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_5 PF07728.9 KFH41258.1 - 0.12 12.1 0.1 1 9.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 KFH41258.1 - 0.12 11.2 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.10 KFH41258.1 - 0.14 11.8 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 NTPase TIP49 PF06068.8 KFH41258.1 - 0.24 10.0 0.0 1.2 7.7 0.0 2.0 3 0 0 3 3 3 0 TIP49 C-terminus Exo_endo_phos PF03372.18 KFH41260.1 - 1e-07 32.2 0.2 1.4e-07 31.7 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CW_binding_1 PF01473.15 KFH41260.1 - 0.05 13.7 1.2 0.18 12.0 0.7 2.1 2 0 0 2 2 2 0 Putative cell wall binding repeat UCH PF00443.24 KFH41261.1 - 4.9e-52 176.6 0.0 5.9e-52 176.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFH41261.1 - 6.6e-17 61.8 0.3 1.1e-15 57.8 0.2 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 KFH41261.1 - 1.2e-10 40.6 0.1 2.7e-10 39.5 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family DUF4407 PF14362.1 KFH41261.1 - 0.55 9.1 6.1 1.6 7.6 4.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Zn_clus PF00172.13 KFH41262.1 - 0.0021 17.9 1.5 0.0035 17.2 1.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFH41263.1 - 2.1e-30 105.4 4.5 2.6e-30 105.1 1.7 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Gal4_dimer PF03902.8 KFH41263.1 - 5.3e-08 32.6 0.5 3.6e-07 29.9 0.1 2.3 2 0 0 2 2 2 1 Gal4-like dimerisation domain Zn_clus PF00172.13 KFH41263.1 - 2e-07 30.8 9.6 3.1e-07 30.2 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFH41264.1 - 1.7e-09 36.8 0.1 3.1e-09 35.9 0.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH41264.1 - 3.3e-06 26.9 6.9 7.7e-06 25.7 4.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CRAL_TRIO PF00650.15 KFH41265.1 - 1.5e-14 53.8 0.0 2e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KFH41265.1 - 0.0026 17.8 0.0 0.008 16.2 0.0 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain RRM_6 PF14259.1 KFH41266.1 - 1.9e-07 30.9 0.1 3.8e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH41266.1 - 0.0025 17.6 0.0 0.0076 16.0 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sugar_tr PF00083.19 KFH41267.1 - 4.3e-119 398.0 18.7 8.8e-119 397.0 13.0 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH41267.1 - 2.1e-21 76.0 53.7 7.9e-12 44.5 16.8 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF3366 PF11846.3 KFH41268.1 - 0.09 12.6 0.1 0.095 12.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) CCDC-167 PF15188.1 KFH41268.1 - 3.3 7.7 6.0 2.4 8.1 2.6 1.9 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 ARPC4 PF05856.7 KFH41269.1 - 1.6e-73 245.6 2.8 2e-73 245.3 1.9 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) DUF1902 PF08972.6 KFH41269.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) CBP PF12192.3 KFH41270.1 - 0.0063 16.4 2.6 0.0063 16.4 1.8 2.9 2 1 1 3 3 3 1 Fungal calcium binding protein PepSY_2 PF13670.1 KFH41270.1 - 2.1 8.2 4.8 0.62 10.0 1.4 1.6 1 1 0 1 1 1 0 Peptidase propeptide and YPEB domain Methyltransf_23 PF13489.1 KFH41271.1 - 2.5e-17 63.0 0.0 3.2e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH41271.1 - 1.2e-11 45.1 0.0 1.8e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH41271.1 - 1.8e-10 41.1 0.0 3.8e-10 40.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH41271.1 - 1.8e-10 41.1 0.0 2.9e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFH41271.1 - 2.7e-09 36.4 0.0 4.8e-09 35.6 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 KFH41271.1 - 1.7e-08 34.2 0.0 3.3e-08 33.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFH41271.1 - 1.6e-06 28.3 0.0 3.7e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFH41271.1 - 0.00095 19.1 0.1 0.0022 18.0 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFH41271.1 - 0.0086 15.4 0.0 0.022 14.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_9 PF08003.6 KFH41271.1 - 0.011 14.4 0.0 0.013 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) TPMT PF05724.6 KFH41271.1 - 0.027 13.9 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) DUF3176 PF11374.3 KFH41272.1 - 2.4e-24 85.3 0.0 4.2e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) SET PF00856.23 KFH41273.1 - 1.6e-18 67.5 0.6 1.6e-18 67.5 0.4 3.0 2 2 0 2 2 2 1 SET domain TraG_N PF07916.6 KFH41273.1 - 7.5 4.8 7.8 12 4.2 5.4 1.2 1 0 0 1 1 1 0 TraG-like protein, N-terminal region WD40 PF00400.27 KFH41274.1 - 8.2e-43 142.7 29.5 1.3e-10 40.7 0.3 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat NACHT PF05729.7 KFH41274.1 - 5e-07 29.5 0.0 1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Nup160 PF11715.3 KFH41274.1 - 9.1e-07 27.3 15.1 0.012 13.8 0.2 4.2 3 1 1 4 4 4 4 Nucleoporin Nup120/160 AAA_16 PF13191.1 KFH41274.1 - 0.00011 22.2 0.6 0.00029 20.8 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 KFH41274.1 - 0.0011 17.9 0.0 0.0019 17.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 KFH41274.1 - 0.04 14.0 0.0 0.099 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 KFH41274.1 - 0.064 12.9 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.1 KFH41275.1 - 3e-06 27.5 0.3 0.00062 20.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KFH41275.1 - 7.9e-05 22.5 2.0 0.0014 18.5 0.1 2.5 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 KFH41275.1 - 0.00011 21.4 0.1 0.00024 20.2 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.1 KFH41275.1 - 0.0002 22.1 0.2 0.00064 20.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KFH41275.1 - 0.00035 20.0 0.0 0.00068 19.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ArgK PF03308.11 KFH41275.1 - 0.0013 17.5 0.2 0.002 16.9 0.1 1.3 1 0 0 1 1 1 1 ArgK protein AAA_16 PF13191.1 KFH41275.1 - 0.0029 17.6 0.4 0.0057 16.6 0.1 1.5 2 0 0 2 2 2 1 AAA ATPase domain PRK PF00485.13 KFH41275.1 - 0.0055 16.2 0.1 0.087 12.3 0.1 2.1 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family KTI12 PF08433.5 KFH41275.1 - 0.012 14.7 0.1 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_19 PF13245.1 KFH41275.1 - 0.033 13.9 0.2 0.074 12.8 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain 6PF2K PF01591.13 KFH41275.1 - 0.039 13.0 0.0 0.061 12.3 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase ABC_tran PF00005.22 KFH41275.1 - 0.052 13.8 0.0 0.13 12.5 0.0 1.6 2 0 0 2 2 2 0 ABC transporter Viral_helicase1 PF01443.13 KFH41275.1 - 0.057 12.9 0.0 0.09 12.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase APS_kinase PF01583.15 KFH41275.1 - 0.07 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Thymidylate_kin PF02223.12 KFH41275.1 - 0.078 12.3 0.1 3 7.1 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase AAA_22 PF13401.1 KFH41275.1 - 0.084 13.0 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF59 PF01883.14 KFH41275.1 - 0.11 12.5 0.1 3.5 7.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF59 T2SE PF00437.15 KFH41275.1 - 0.11 11.3 0.1 0.19 10.5 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein MMR_HSR1 PF01926.18 KFH41275.1 - 0.16 11.9 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase His_Phos_1 PF00300.17 KFH41276.1 - 1.5e-30 106.3 0.0 1.8e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) WD40 PF00400.27 KFH41277.1 - 8.9e-30 101.4 8.0 8.4e-07 28.6 0.9 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KFH41277.1 - 0.031 12.5 0.3 1.1 7.4 0.0 2.7 3 1 0 3 3 3 0 Cytochrome D1 heme domain GSIII_N PF12437.3 KFH41277.1 - 0.032 13.6 0.1 0.049 13.0 0.1 1.3 1 0 0 1 1 1 0 Glutamine synthetase type III N terminal PQQ PF01011.16 KFH41277.1 - 0.19 11.3 2.9 10 5.8 0.2 3.3 3 0 0 3 3 3 0 PQQ enzyme repeat Inhibitor_I71 PF12628.2 KFH41277.1 - 0.26 10.9 0.5 0.44 10.1 0.2 1.5 1 1 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor PQQ_3 PF13570.1 KFH41277.1 - 1.9 8.8 6.8 5 7.5 0.1 4.0 4 0 0 4 4 4 0 PQQ-like domain Septin PF00735.13 KFH41278.1 - 8.9e-117 389.0 0.3 1.4e-116 388.4 0.2 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KFH41278.1 - 5.6e-07 29.5 0.0 9.6e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFH41278.1 - 2.3e-06 27.1 0.2 5.7e-05 22.6 0.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KFH41278.1 - 1e-05 24.8 0.0 2.6e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 KFH41278.1 - 0.0019 18.6 0.1 0.0081 16.6 0.1 2.1 2 0 0 2 2 1 1 Miro-like protein AAA_22 PF13401.1 KFH41278.1 - 0.0031 17.6 0.4 0.014 15.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.1 KFH41278.1 - 0.0035 16.9 0.1 0.0071 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AIG1 PF04548.11 KFH41278.1 - 0.0058 15.7 0.0 0.013 14.6 0.0 1.6 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.8 KFH41278.1 - 0.0066 15.3 0.0 0.013 14.3 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Pox_A32 PF04665.7 KFH41278.1 - 0.011 15.0 0.1 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein FtsK_SpoIIIE PF01580.13 KFH41278.1 - 0.012 15.1 0.9 0.019 14.4 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family Ras PF00071.17 KFH41278.1 - 0.016 14.5 0.7 0.054 12.8 0.4 2.0 2 1 0 2 2 2 0 Ras family DUF2968 PF11180.3 KFH41278.1 - 0.024 13.9 6.1 0.064 12.6 4.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) T2SE PF00437.15 KFH41278.1 - 0.036 12.9 0.4 0.1 11.4 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_tran PF00005.22 KFH41278.1 - 0.037 14.3 0.3 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.7 KFH41278.1 - 0.038 13.6 0.0 0.077 12.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.21 KFH41278.1 - 0.06 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.1 KFH41278.1 - 0.067 13.1 3.0 0.21 11.5 0.1 2.8 2 1 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.18 KFH41278.1 - 0.068 12.9 7.5 0.72 9.6 0.0 3.1 2 1 1 3 3 3 0 Dynamin family PduV-EutP PF10662.4 KFH41278.1 - 0.091 12.2 1.0 2.4 7.6 0.2 2.7 2 1 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation ArgK PF03308.11 KFH41278.1 - 0.1 11.3 2.4 2.4 6.8 0.0 3.0 3 0 0 3 3 3 0 ArgK protein KAP_NTPase PF07693.9 KFH41278.1 - 0.11 11.4 3.0 0.21 10.5 2.1 1.7 1 1 0 1 1 1 0 KAP family P-loop domain RNA_helicase PF00910.17 KFH41278.1 - 0.11 12.6 0.0 0.36 11.0 0.0 1.9 2 0 0 2 2 1 0 RNA helicase Ribosomal_L6e PF01159.14 KFH41278.1 - 0.12 12.6 5.5 3.8 7.7 0.1 3.3 3 0 0 3 3 3 0 Ribosomal protein L6e Atg14 PF10186.4 KFH41278.1 - 0.45 9.4 6.7 1 8.2 4.6 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Myc-LZ PF02344.10 KFH41278.1 - 0.46 10.1 7.8 0.2 11.2 1.1 2.6 2 0 0 2 2 2 0 Myc leucine zipper domain AAA_23 PF13476.1 KFH41278.1 - 7.3 6.8 19.6 2e+02 2.1 13.6 2.1 1 1 0 1 1 1 0 AAA domain Glyco_transf_15 PF01793.11 KFH41279.1 - 5.2e-134 446.3 8.8 6.3e-134 446.1 6.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Alk_phosphatase PF00245.15 KFH41280.1 - 1.3e-66 225.0 0.0 3.6e-66 223.5 0.0 1.6 1 1 0 1 1 1 1 Alkaline phosphatase Phosphodiest PF01663.17 KFH41280.1 - 5.7e-06 25.8 1.6 8.9e-06 25.2 0.2 1.9 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KFH41280.1 - 2.2e-05 23.8 0.2 4.8e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 KFH41280.1 - 0.0028 16.1 0.1 0.0045 15.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) FTA4 PF13093.1 KFH41280.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 BCDHK_Adom3 PF10436.4 KFH41281.1 - 2.5e-44 150.6 0.9 3.3e-44 150.2 0.1 1.6 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KFH41281.1 - 3.9e-10 39.4 0.0 5.1e-09 35.8 0.0 2.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KFH41281.1 - 6.4e-05 22.6 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 KFH41281.1 - 0.068 12.9 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain NAP PF00956.13 KFH41283.1 - 1.9e-44 151.6 6.0 3.3e-44 150.8 4.2 1.4 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) BUD22 PF09073.5 KFH41283.1 - 9.7e-05 21.6 11.7 0.00014 21.1 8.1 1.2 1 0 0 1 1 1 1 BUD22 Cache_2 PF08269.6 KFH41283.1 - 0.1 12.5 0.0 0.1 12.5 0.0 2.3 4 0 0 4 4 4 0 Cache domain USP7_ICP0_bdg PF12436.3 KFH41284.1 - 1.1e-79 267.2 0.0 1.1e-77 260.6 0.0 3.1 2 1 1 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 KFH41284.1 - 3.9e-74 248.6 2.5 4.8e-72 241.8 0.2 4.2 4 1 0 4 4 4 1 Ubiquitin-specific protease C-terminal UCH PF00443.24 KFH41284.1 - 2.6e-56 190.7 2.3 3.9e-56 190.1 1.6 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFH41284.1 - 3.3e-29 102.2 0.1 4.9e-29 101.7 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 KFH41284.1 - 1.7e-12 47.6 0.0 1.3e-11 44.8 0.0 2.6 2 0 0 2 2 2 1 MATH domain Abhydrolase_2 PF02230.11 KFH41286.1 - 2.7e-12 46.6 0.0 5.2e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KFH41286.1 - 0.00022 21.2 0.2 0.00028 20.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH41286.1 - 0.00041 20.1 0.1 0.00062 19.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family TGT PF01702.13 KFH41287.1 - 3.7e-35 121.3 0.0 6.7e-35 120.4 0.0 1.4 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase AMPKBI PF04739.10 KFH41288.1 - 1.6e-31 108.1 2.8 3.3e-31 107.1 0.3 2.3 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain Asparaginase PF00710.15 KFH41289.1 - 2.2e-99 332.2 0.0 3e-99 331.8 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 KFH41289.1 - 4.9e-15 55.6 0.3 9.3e-15 54.7 0.2 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFH41289.1 - 1.8e-12 46.3 0.8 6.9e-07 28.7 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KFH41289.1 - 3.8e-08 33.6 0.4 3.1e-06 27.5 0.0 2.7 1 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFH41289.1 - 8e-08 32.2 0.3 4.8e-06 26.6 0.1 2.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFH41289.1 - 5.3e-06 26.1 1.5 0.00093 19.2 0.0 4.0 5 0 0 5 5 5 1 Ankyrin repeat Fungal_trans PF04082.13 KFH41290.1 - 9e-12 44.4 0.0 1.4e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH41290.1 - 4e-07 29.8 8.6 6.7e-07 29.1 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 KFH41291.1 - 3.4e-65 219.7 0.0 4.1e-65 219.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH41291.1 - 1e-30 106.6 0.0 1.3e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH41291.1 - 0.0028 16.6 0.0 0.0046 15.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Peptidase_M22 PF00814.20 KFH41292.1 - 1.6e-82 277.0 0.0 1.9e-82 276.7 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Staygreen PF12638.2 KFH41292.1 - 0.18 11.3 0.0 1.2 8.6 0.0 2.0 2 0 0 2 2 2 0 Staygreen protein Spc97_Spc98 PF04130.8 KFH41293.1 - 9.1e-65 218.9 0.2 1.8e-64 218.0 0.0 1.6 2 0 0 2 2 2 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 KFH41293.1 - 6e-06 24.6 0.0 1.3e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 CutC PF03932.9 KFH41294.1 - 6.2e-25 87.6 0.0 2.5e-24 85.6 0.0 1.9 1 1 0 1 1 1 1 CutC family DUF4243 PF14027.1 KFH41295.1 - 2.5e-77 260.5 2.3 3.2e-77 260.2 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) WD40 PF00400.27 KFH41296.1 - 1.8e-53 176.5 33.4 1e-10 41.0 0.0 12.3 13 0 0 13 13 13 8 WD domain, G-beta repeat Utp12 PF04003.7 KFH41296.1 - 4.3e-27 94.1 0.0 6.5e-27 93.6 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 KFH41296.1 - 7.1e-07 29.1 1.1 0.022 14.4 0.0 5.3 6 1 1 7 7 7 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KFH41296.1 - 0.0004 18.6 1.1 0.31 9.1 0.2 4.2 2 1 2 4 4 4 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFH41296.1 - 0.0014 17.4 0.1 6.4 5.3 0.2 4.5 1 1 0 2 2 2 1 Nup133 N terminal like Cytochrom_D1 PF02239.11 KFH41296.1 - 0.015 13.6 0.5 3.3 5.9 0.0 3.7 3 2 3 6 6 6 0 Cytochrome D1 heme domain Nbas_N PF15492.1 KFH41296.1 - 0.042 12.9 0.7 17 4.4 0.0 4.0 4 2 1 5 5 5 0 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.7 KFH41296.1 - 0.064 11.0 0.0 1.5 6.4 0.0 2.3 2 0 0 2 2 2 0 IKI3 family LCCL PF03815.14 KFH41297.1 - 2.3e-19 69.1 0.1 3.9e-19 68.4 0.1 1.4 1 0 0 1 1 1 1 LCCL domain GtrA PF04138.9 KFH41297.1 - 3.6 7.5 8.9 11 6.0 1.4 2.7 2 1 0 3 3 3 0 GtrA-like protein Lactamase_B PF00753.22 KFH41300.1 - 2.3e-23 82.8 0.8 4.3e-23 81.9 0.5 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KFH41300.1 - 4.1e-05 23.2 0.0 7e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KFH41300.1 - 0.0036 17.0 0.0 0.0055 16.4 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain KaiB PF07689.7 KFH41300.1 - 0.077 12.4 0.1 0.52 9.8 0.0 2.1 2 0 0 2 2 2 0 KaiB domain Ytp1 PF10355.4 KFH41301.1 - 1.1e-111 372.3 5.8 1.9e-111 371.6 4.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KFH41301.1 - 4.4e-33 113.0 15.6 8e-33 112.1 3.1 3.4 2 1 1 3 3 3 2 Domain of unknown function (DUF2427) DUF3481 PF11980.3 KFH41301.1 - 0.5 10.2 0.1 0.5 10.2 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3481) RTA1 PF04479.8 KFH41302.1 - 1.2e-11 44.5 4.6 5.1e-11 42.4 3.2 1.8 1 1 0 1 1 1 1 RTA1 like protein Ninjurin PF04923.7 KFH41302.1 - 0.058 13.1 0.9 0.11 12.2 0.7 1.4 1 0 0 1 1 1 0 Ninjurin DUF3112 PF11309.3 KFH41302.1 - 2 8.1 8.2 6.7 6.4 5.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) Rsa3 PF14615.1 KFH41303.1 - 4.6e-18 64.2 0.6 5.8e-18 63.9 0.4 1.2 1 0 0 1 1 1 1 Ribosome-assembly protein 3 adh_short PF00106.20 KFH41304.1 - 1.1e-16 61.1 0.0 2e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH41304.1 - 5e-08 32.8 0.0 8e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFH41304.1 - 0.0068 16.2 0.0 0.019 14.7 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KFH41305.1 - 1.1e-17 64.6 0.0 1.6e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KFH41305.1 - 1.3e-14 54.0 0.0 1.5e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KFH41305.1 - 3.1e-14 53.0 0.1 7.1e-14 51.8 0.1 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFH41305.1 - 1.2e-09 37.2 0.0 2.2e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KFH41305.1 - 1.8e-07 30.3 0.0 6.2e-06 25.3 0.0 2.4 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 KFH41305.1 - 0.00026 20.9 0.1 0.0017 18.3 0.0 2.3 2 1 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KFH41305.1 - 0.00081 18.3 0.4 0.035 13.0 0.3 2.3 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 KFH41305.1 - 0.0016 18.1 0.0 0.6 9.7 0.0 2.6 2 0 0 2 2 2 2 KR domain Saccharop_dh PF03435.13 KFH41305.1 - 0.016 14.2 0.0 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase DDE_Tnp_1_3 PF13612.1 KFH41305.1 - 0.05 13.3 0.0 0.38 10.4 0.0 2.0 2 0 0 2 2 2 0 Transposase DDE domain Polysacc_synt_2 PF02719.10 KFH41305.1 - 0.16 10.8 0.0 0.35 9.7 0.0 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein EI24 PF07264.6 KFH41306.1 - 1.9e-06 27.4 11.3 0.00015 21.3 7.8 2.7 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Inp1 PF12634.2 KFH41307.1 - 0.083 12.5 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Inheritance of peroxisomes protein 1 SNF2_N PF00176.18 KFH41308.1 - 7.6e-70 235.0 0.0 1e-69 234.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 KFH41308.1 - 6.3e-60 202.3 3.8 3.7e-59 199.8 2.8 2.0 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.26 KFH41308.1 - 4.9e-13 48.7 0.0 2e-12 46.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFH41308.1 - 2.9e-07 30.5 0.0 5.9e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 KFH41308.1 - 8.8e-05 21.4 0.0 0.00072 18.4 0.0 2.2 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.1 KFH41308.1 - 0.041 14.0 0.1 0.34 11.0 0.0 2.6 2 1 0 2 2 2 0 AAA domain PCI PF01399.22 KFH41309.1 - 1.9e-10 40.9 0.1 6.3e-10 39.3 0.0 1.9 2 0 0 2 2 2 1 PCI domain LolB PF03550.9 KFH41309.1 - 0.079 12.5 0.3 0.14 11.7 0.2 1.4 1 0 0 1 1 1 0 Outer membrane lipoprotein LolB Bromodomain PF00439.20 KFH41310.1 - 5.3e-37 125.5 0.1 2.5e-19 68.9 0.2 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 KFH41310.1 - 1.7e-16 60.0 1.0 4.4e-16 58.6 0.2 2.2 3 0 0 3 3 3 1 BAH domain CDC45 PF02724.9 KFH41310.1 - 0.0015 16.7 5.0 0.0025 15.9 3.5 1.3 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.7 KFH41310.1 - 0.0042 15.0 8.0 0.0089 14.0 5.5 1.5 1 0 0 1 1 1 1 Nop14-like family Ded_cyto PF06920.8 KFH41310.1 - 0.074 12.3 0.2 0.16 11.2 0.2 1.5 1 0 0 1 1 1 0 Dedicator of cytokinesis NOA36 PF06524.7 KFH41310.1 - 5.5 6.1 10.4 14 4.8 7.2 1.6 1 0 0 1 1 1 0 NOA36 protein UCH PF00443.24 KFH41311.1 - 9.9e-55 185.5 4.3 1.7e-54 184.7 3.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFH41311.1 - 2.1e-33 116.0 3.0 2.9e-33 115.5 2.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KFH41311.1 - 0.0029 17.7 0.0 0.0029 17.7 0.0 2.7 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein zf-CCHC PF00098.18 KFH41311.1 - 8.4 6.5 9.0 92 3.2 0.0 4.4 4 0 0 4 4 4 0 Zinc knuckle OPT PF03169.10 KFH41312.1 - 2.6e-172 574.5 44.2 3e-172 574.3 30.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Gaa1 PF04114.9 KFH41313.1 - 1.7e-99 333.8 2.4 2.4e-99 333.3 1.7 1.3 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component Rhomboid PF01694.17 KFH41314.1 - 1.1e-13 51.4 9.1 1.1e-13 51.4 6.3 1.5 2 0 0 2 2 2 1 Rhomboid family DUF3487 PF11990.3 KFH41314.1 - 0.4 10.1 5.1 0.6 9.5 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3487) 5TM-5TMR_LYT PF07694.7 KFH41314.1 - 0.71 9.1 11.9 0.69 9.2 5.8 2.4 2 1 0 2 2 2 0 5TMR of 5TMR-LYT OTU PF02338.14 KFH41315.1 - 2e-10 41.3 0.0 3.4e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease zf-A20 PF01754.11 KFH41315.1 - 0.00038 19.9 1.4 0.65 9.6 0.1 2.5 2 0 0 2 2 2 2 A20-like zinc finger Mito_carr PF00153.22 KFH41316.1 - 2.3e-45 152.2 1.7 5.2e-20 70.9 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Exo_endo_phos PF03372.18 KFH41317.1 - 2.1e-12 47.5 0.2 2.4e-12 47.3 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Methyltransf_11 PF08241.7 KFH41318.1 - 0.0015 18.9 0.0 0.0031 17.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH41318.1 - 0.0082 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KFH41318.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Ubie_methyltran PF01209.13 KFH41318.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.12 KFH41318.1 - 0.75 8.7 0.0 1.1 8.1 0.0 1.1 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family TPR_12 PF13424.1 KFH41320.1 - 6.2e-24 83.7 18.8 2.4e-11 43.4 0.6 5.7 3 1 3 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.1 KFH41320.1 - 1.2e-11 44.1 26.2 5.2e-06 26.2 0.0 7.1 7 0 0 7 7 6 2 Tetratricopeptide repeat NB-ARC PF00931.17 KFH41320.1 - 1.2e-08 34.1 0.0 3.1e-08 32.8 0.0 1.6 1 1 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 KFH41320.1 - 1.7e-05 24.9 0.0 8e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain TPR_2 PF07719.12 KFH41320.1 - 0.0001 21.9 19.7 0.095 12.6 0.0 6.4 7 0 0 7 7 7 3 Tetratricopeptide repeat AAA PF00004.24 KFH41320.1 - 0.0002 21.5 0.0 0.001 19.2 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFH41320.1 - 0.00029 20.8 1.4 0.0011 19.0 0.0 2.8 3 0 0 3 3 2 1 AAA ATPase domain TPR_14 PF13428.1 KFH41320.1 - 0.00057 20.2 14.9 4.9 8.0 0.0 7.2 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFH41320.1 - 0.0012 18.3 5.8 0.57 9.8 0.1 4.4 4 1 0 4 4 4 2 TPR repeat AAA_17 PF13207.1 KFH41320.1 - 0.0013 19.4 0.0 0.0071 17.1 0.0 2.3 2 0 0 2 2 1 1 AAA domain TPR_5 PF12688.2 KFH41320.1 - 0.0015 18.5 7.9 0.29 11.1 0.7 3.7 2 1 1 3 3 3 2 Tetratrico peptide repeat TPR_16 PF13432.1 KFH41320.1 - 0.0019 18.8 17.6 0.035 14.7 0.9 5.6 4 2 1 6 6 5 2 Tetratricopeptide repeat AAA_33 PF13671.1 KFH41320.1 - 0.0024 17.7 0.0 0.0068 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KFH41320.1 - 0.0026 17.4 0.0 0.0062 16.2 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase AAA_18 PF13238.1 KFH41320.1 - 0.0084 16.4 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Abhydrolase_6 PF12697.2 KFH41320.1 - 0.013 15.3 0.0 0.037 13.9 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family AAA_5 PF07728.9 KFH41320.1 - 0.015 15.0 0.0 0.045 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF676 PF05057.9 KFH41320.1 - 0.016 14.4 0.0 0.035 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) TPR_8 PF13181.1 KFH41320.1 - 0.024 14.3 0.4 13 5.8 0.0 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat AAA_14 PF13173.1 KFH41320.1 - 0.03 14.2 0.0 0.14 12.0 0.0 2.2 1 1 0 1 1 1 0 AAA domain TPR_7 PF13176.1 KFH41320.1 - 0.032 14.0 18.2 0.84 9.5 0.0 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat AAA_19 PF13245.1 KFH41320.1 - 0.049 13.3 0.2 0.31 10.7 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain KaiC PF06745.8 KFH41320.1 - 0.11 11.6 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 KaiC RNA_helicase PF00910.17 KFH41320.1 - 0.18 11.9 0.0 0.61 10.2 0.0 1.8 2 0 0 2 2 1 0 RNA helicase TPR_1 PF00515.23 KFH41320.1 - 0.22 11.2 0.0 0.22 11.2 0.0 4.4 6 0 0 6 6 4 0 Tetratricopeptide repeat SAP PF02037.22 KFH41321.1 - 1.5e-14 53.0 0.2 3.1e-14 52.0 0.2 1.6 1 0 0 1 1 1 1 SAP domain HeH PF12949.2 KFH41321.1 - 0.01 15.3 0.3 0.039 13.5 0.2 1.9 1 1 0 1 1 1 0 HeH/LEM domain Abhydrolase_6 PF12697.2 KFH41322.1 - 8.1e-28 97.8 7.2 1.1e-27 97.3 5.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH41322.1 - 7.1e-19 67.9 0.1 2e-18 66.5 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KFH41322.1 - 1.2e-05 25.0 0.0 3.5e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 KFH41322.1 - 3.4e-05 23.1 0.6 0.067 12.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KFH41322.1 - 6.1e-05 22.6 0.1 0.0019 17.7 0.1 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 KFH41322.1 - 0.00081 19.6 0.1 0.0017 18.5 0.1 1.6 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.8 KFH41322.1 - 0.011 15.3 0.4 0.024 14.2 0.3 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold APH PF01636.18 KFH41323.1 - 9.9e-14 51.6 0.0 1.8e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4530 PF15039.1 KFH41323.1 - 0.0045 16.8 1.0 0.01 15.7 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4530) Metallophos PF00149.23 KFH41324.1 - 4.3e-13 49.1 0.1 6.9e-13 48.4 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KFH41324.1 - 0.0015 18.4 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.20 KFH41325.1 - 1.6e-47 161.8 0.0 2e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH41325.1 - 6.7e-28 97.4 0.0 9.9e-28 96.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH41325.1 - 0.031 13.2 0.0 0.13 11.1 0.0 1.8 1 1 0 1 1 1 0 Kinase-like Dscam_C PF12355.3 KFH41325.1 - 7.4 6.8 19.3 3 8.1 4.9 3.6 3 0 0 3 3 3 0 Down syndrome cell adhesion molecule C terminal GCD14 PF08704.5 KFH41327.1 - 1.2e-05 24.9 0.0 0.13 11.7 0.0 2.6 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Clr5 PF14420.1 KFH41331.1 - 3.1e-21 75.0 0.4 7.4e-21 73.7 0.3 1.7 1 0 0 1 1 1 1 Clr5 domain Glyco_hydro_7 PF00840.15 KFH41332.1 - 1.5e-192 639.7 16.4 1.8e-192 639.5 11.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DUF4506 PF14958.1 KFH41332.1 - 0.017 14.7 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4506) zinc-ribbons_6 PF07191.7 KFH41333.1 - 0.24 11.2 16.4 0.71 9.6 2.9 2.1 1 1 1 2 2 2 0 zinc-ribbons DUF2614 PF11023.3 KFH41333.1 - 0.45 10.3 4.7 0.095 12.4 0.7 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) zf-ribbon_3 PF13248.1 KFH41333.1 - 0.8 8.9 8.8 3.1 7.1 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-FPG_IleRS PF06827.9 KFH41333.1 - 0.98 9.1 7.3 3 7.5 0.3 3.0 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS ADH_zinc_N PF00107.21 KFH41334.1 - 1.6e-08 34.1 0.0 4e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFH41334.1 - 8.8e-08 33.0 0.0 2.9e-07 31.4 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFH41334.1 - 1.7e-05 24.5 0.5 0.00088 19.0 0.1 2.5 1 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ketoacyl-synt PF00109.21 KFH41335.1 - 3.2e-79 266.0 0.1 6.5e-79 264.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KFH41335.1 - 5.2e-59 198.9 0.6 3e-58 196.4 0.3 2.5 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 KFH41335.1 - 1.5e-54 185.4 0.0 2.5e-54 184.7 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KFH41335.1 - 3.9e-54 183.8 3.5 7e-54 182.9 2.4 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KFH41335.1 - 5e-49 166.4 0.5 1.9e-48 164.5 0.4 2.1 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KFH41335.1 - 1.6e-38 131.2 0.1 4.1e-38 129.8 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KFH41335.1 - 7.5e-20 71.2 0.1 5e-19 68.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH41335.1 - 3.6e-11 43.0 0.0 7.3e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH41335.1 - 5.3e-08 33.2 0.0 1.5e-07 31.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH41335.1 - 7e-08 33.0 0.0 5.9e-07 30.0 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain ADH_N PF08240.7 KFH41335.1 - 1e-07 31.6 0.2 4.1e-07 29.7 0.1 2.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_31 PF13847.1 KFH41335.1 - 2.4e-06 27.2 0.0 5.3e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFH41335.1 - 0.0005 19.2 0.0 0.001 18.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 KFH41335.1 - 0.00063 18.8 0.3 0.0015 17.5 0.2 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.20 KFH41335.1 - 0.0025 18.0 0.0 0.0069 16.6 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ACP_syn_III PF08545.5 KFH41335.1 - 0.0069 16.0 0.1 0.026 14.1 0.1 2.1 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III NodS PF05401.6 KFH41335.1 - 0.033 13.5 0.0 0.089 12.1 0.0 1.7 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_28 PF02636.12 KFH41335.1 - 0.1 11.9 0.0 0.36 10.1 0.0 1.9 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase NNMT_PNMT_TEMT PF01234.12 KFH41335.1 - 0.19 10.6 0.0 0.59 9.0 0.0 1.8 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family p450 PF00067.17 KFH41336.1 - 1.1e-32 113.2 0.0 1.2e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NIF PF03031.13 KFH41337.1 - 9.5e-19 67.6 0.0 1.2e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Ribosomal_S9 PF00380.14 KFH41338.1 - 2.2e-35 121.5 0.4 7.9e-35 119.7 0.4 1.8 2 0 0 2 2 2 1 Ribosomal protein S9/S16 ABC1 PF03109.11 KFH41339.1 - 2.9e-30 104.6 0.0 5.4e-30 103.8 0.0 1.5 1 0 0 1 1 1 1 ABC1 family EPL1 PF10513.4 KFH41340.1 - 4.7e-30 104.9 0.7 4.7e-30 104.9 0.5 2.3 3 0 0 3 3 3 1 Enhancer of polycomb-like Metallophos PF00149.23 KFH41341.1 - 4.5e-40 137.1 0.1 6.9e-40 136.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 KFH41341.1 - 8.4e-30 102.6 0.8 2.5e-29 101.1 0.1 2.1 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_11 PF13414.1 KFH41341.1 - 4.4e-23 80.6 5.4 7.2e-17 60.7 0.6 2.5 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KFH41341.1 - 1.3e-18 65.7 2.5 3.6e-05 23.1 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFH41341.1 - 3.1e-15 54.7 1.6 0.00053 19.7 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFH41341.1 - 1.4e-05 24.9 1.1 0.27 11.5 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFH41341.1 - 1.4e-05 25.6 2.0 0.021 15.4 0.2 3.3 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFH41341.1 - 3e-05 24.2 2.0 0.0039 17.4 1.4 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFH41341.1 - 3.9e-05 23.9 1.0 0.99 10.2 0.0 3.8 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFH41341.1 - 7.5e-05 22.5 0.4 0.0017 18.1 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFH41341.1 - 0.00044 19.8 1.0 2.9 7.8 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFH41341.1 - 0.003 17.8 0.4 0.52 10.8 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 KFH41341.1 - 0.015 15.1 0.1 0.12 12.2 0.0 2.3 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 KFH41341.1 - 0.018 15.1 0.6 0.044 13.9 0.4 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KFH41341.1 - 0.019 14.9 1.1 2.5 8.1 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFH41341.1 - 0.026 14.3 0.0 0.12 12.2 0.0 2.1 2 0 0 2 2 1 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 KFH41341.1 - 0.031 13.5 0.1 13 5.0 0.0 3.3 3 0 0 3 3 3 0 SHNi-TPR Spt4 PF06093.8 KFH41342.1 - 2e-32 110.9 0.2 2.5e-32 110.5 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Thioredoxin_2 PF13098.1 KFH41342.1 - 0.035 14.3 0.0 0.047 13.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain Cys_rich_CPXG PF14255.1 KFH41342.1 - 2.8 7.8 6.2 25 4.8 0.1 2.6 2 1 0 2 2 2 0 Cysteine-rich CPXCG DUF572 PF04502.8 KFH41343.1 - 1e-70 238.5 7.1 1.2e-70 238.3 4.9 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) OspD PF03207.8 KFH41343.1 - 0.025 13.7 0.6 0.038 13.1 0.4 1.2 1 0 0 1 1 1 0 Borrelia outer surface protein D (OspD) Benyvirus_14KDa PF07255.6 KFH41343.1 - 0.12 12.1 0.2 0.32 10.8 0.1 1.7 1 1 0 1 1 1 0 Benyvirus 14KDa protein Acetyltransf_2 PF00797.12 KFH41344.1 - 2e-25 89.7 0.0 1.1e-23 84.0 0.0 2.1 1 1 0 1 1 1 1 N-acetyltransferase p450 PF00067.17 KFH41345.1 - 1.6e-37 129.1 0.0 1.1e-22 80.2 0.0 2.4 2 0 0 2 2 2 2 Cytochrome P450 Trp_DMAT PF11991.3 KFH41346.1 - 2.1e-75 254.2 0.0 5.7e-73 246.1 0.0 2.0 1 1 0 1 1 1 1 Tryptophan dimethylallyltransferase Aldo_ket_red PF00248.16 KFH41347.1 - 4.6e-41 140.5 0.0 6e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF947 PF06102.7 KFH41348.1 - 1.4e-49 168.1 22.7 1.4e-49 168.1 15.7 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF947) Es2 PF09751.4 KFH41349.1 - 4.8e-94 316.1 0.0 1.1e-93 314.9 0.0 1.5 1 1 0 1 1 1 1 Nuclear protein Es2 EF1G PF00647.14 KFH41350.1 - 1.4e-39 134.1 0.1 2.5e-39 133.2 0.1 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 KFH41350.1 - 8e-15 54.6 0.0 3.6e-14 52.5 0.0 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFH41350.1 - 1.3e-11 44.2 0.0 8.2e-11 41.6 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFH41350.1 - 2e-06 28.1 0.0 4.1e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KFH41350.1 - 7.6e-06 26.0 0.0 3e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KFH41350.1 - 0.0023 18.1 0.0 0.005 17.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain EF-hand_1 PF00036.27 KFH41352.1 - 1.4e-25 86.5 14.6 2.5e-07 29.4 0.5 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KFH41352.1 - 1e-22 79.9 4.0 4e-12 46.0 0.5 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFH41352.1 - 2.6e-19 67.3 7.5 0.00012 21.6 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KFH41352.1 - 2.4e-18 64.5 15.4 8.5e-07 28.0 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 KFH41352.1 - 2.7e-15 55.7 15.1 1.3e-05 24.7 0.8 4.5 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.2 KFH41352.1 - 6.3e-07 29.0 8.0 0.0012 18.5 0.2 3.8 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KFH41352.1 - 5.7e-06 26.3 0.0 0.0017 18.3 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 KFH41352.1 - 0.018 14.9 0.1 1.2 9.0 0.0 2.9 2 1 1 3 3 3 0 EF-hand domain Kin17_mid PF10357.4 KFH41353.1 - 5.2e-51 171.5 0.9 5.2e-51 171.5 0.6 1.7 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 KFH41353.1 - 0.0033 17.5 3.0 0.0033 17.5 2.1 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFH41353.1 - 0.019 15.0 2.0 0.068 13.2 0.1 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KFH41353.1 - 0.04 14.1 4.6 0.04 14.1 3.2 1.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Ecl1 PF12855.2 KFH41353.1 - 0.11 11.8 0.2 0.23 10.7 0.1 1.5 1 0 0 1 1 1 0 Life-span regulatory factor YqfQ PF14181.1 KFH41354.1 - 0.12 12.4 0.2 0.13 12.2 0.1 1.0 1 0 0 1 1 1 0 YqfQ-like protein Med5 PF08689.5 KFH41355.1 - 7.3e-185 616.5 0.0 9.1e-185 616.1 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 AMP-binding_C PF13193.1 KFH41356.1 - 0.011 16.6 0.0 0.039 14.9 0.0 2.0 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Amidoligase_2 PF12224.3 KFH41357.1 - 3.7e-17 62.8 0.0 1.6e-16 60.7 0.0 1.9 2 0 0 2 2 2 1 Putative amidoligase enzyme Brix PF04427.13 KFH41358.1 - 2e-37 128.7 0.2 2.6e-37 128.3 0.1 1.2 1 0 0 1 1 1 1 Brix domain TPR_11 PF13414.1 KFH41359.1 - 2.3e-25 87.9 7.8 4.4e-10 39.0 0.6 4.4 3 1 1 4 4 4 4 TPR repeat TPR_1 PF00515.23 KFH41359.1 - 9.2e-23 78.8 7.1 1.6e-07 30.5 0.0 6.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFH41359.1 - 1.8e-22 77.4 5.6 4.8e-07 29.2 0.0 6.1 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFH41359.1 - 1.8e-17 62.2 11.5 1.5e-05 25.1 0.1 6.2 5 1 2 7 7 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFH41359.1 - 1.8e-17 63.4 6.7 4.5e-06 27.1 0.0 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFH41359.1 - 1.3e-14 54.2 6.3 0.0025 18.1 0.4 5.2 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 KFH41359.1 - 2.2e-14 52.3 5.3 0.024 14.8 0.1 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 KFH41359.1 - 5.8e-13 47.5 2.9 0.0011 18.5 0.0 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFH41359.1 - 9.2e-13 47.9 7.6 4.6e-06 26.4 0.4 4.6 3 2 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFH41359.1 - 2.1e-12 45.8 3.3 0.00011 21.7 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFH41359.1 - 2.1e-09 37.2 1.5 0.57 10.7 0.1 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFH41359.1 - 7.7e-09 35.2 2.2 0.014 15.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.1 KFH41359.1 - 8.9e-08 32.1 1.9 0.047 13.7 0.1 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_15 PF13429.1 KFH41359.1 - 2e-05 23.7 1.0 0.15 11.0 0.2 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_3 PF07720.7 KFH41359.1 - 0.0095 15.7 0.2 7.3 6.4 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 KFH41359.1 - 0.21 11.5 6.1 0.51 10.3 0.3 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat Cys_Met_Meta_PP PF01053.15 KFH41360.1 - 2.3e-138 460.7 0.1 2.6e-138 460.5 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KFH41360.1 - 1e-07 31.3 0.1 1.7e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KFH41360.1 - 4.2e-07 29.0 2.0 5.2e-07 28.7 0.7 1.6 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KFH41360.1 - 1.1e-06 27.9 0.8 1.9e-06 27.1 0.6 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.11 KFH41360.1 - 0.0022 16.7 0.2 0.0033 16.1 0.1 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 KFH41360.1 - 0.0024 17.0 0.6 0.0046 16.1 0.4 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 KFH41360.1 - 0.011 14.0 0.0 0.016 13.5 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase 2-Hacid_dh PF00389.25 KFH41360.1 - 0.086 12.3 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Zn_clus PF00172.13 KFH41362.1 - 2.4e-08 33.7 13.4 3.9e-08 33.0 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 6PGD PF00393.14 KFH41363.1 - 1.1e-60 205.3 0.0 1.3e-60 205.1 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KFH41363.1 - 2.9e-30 105.2 0.0 4.7e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 KFH41363.1 - 0.00012 21.6 0.0 0.00022 20.7 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 KFH41363.1 - 0.00016 21.4 0.0 0.0003 20.5 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KFH41363.1 - 0.00099 18.8 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 KFH41363.1 - 0.0013 18.1 0.0 0.0024 17.2 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.12 KFH41363.1 - 0.01 16.2 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 KFH41363.1 - 0.071 12.2 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 KFH41363.1 - 0.1 13.1 0.0 0.23 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_11 PF14833.1 KFH41363.1 - 0.17 11.9 0.6 2.4 8.2 0.0 2.5 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase SET PF00856.23 KFH41364.1 - 1.6e-08 34.9 0.0 1.6e-07 31.8 0.0 2.5 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.13 KFH41364.1 - 9.4e-08 31.8 14.4 9.4e-08 31.8 10.0 2.4 2 0 0 2 2 2 1 MYND finger Shisa PF13908.1 KFH41365.1 - 0.0063 16.7 0.0 0.015 15.5 0.0 1.7 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator SKG6 PF08693.5 KFH41365.1 - 0.049 12.9 2.3 0.085 12.1 1.6 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain VPEP PF07589.6 KFH41366.1 - 7.4 6.6 6.5 4.4 7.3 0.5 2.4 2 0 0 2 2 2 0 PEP-CTERM motif adh_short PF00106.20 KFH41367.1 - 4.3e-30 104.8 2.7 6.7e-30 104.2 1.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH41367.1 - 1.5e-24 87.1 0.0 1.8e-24 86.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH41367.1 - 6.6e-09 35.6 0.9 1.2e-08 34.8 0.4 1.5 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 KFH41367.1 - 0.0079 15.2 0.2 0.018 14.1 0.1 1.5 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pyr_redox PF00070.22 KFH41367.1 - 0.12 12.8 0.5 0.23 11.9 0.4 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase BSP_II PF05432.6 KFH41368.1 - 0.059 12.6 4.7 0.087 12.0 3.3 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF2457 PF10446.4 KFH41368.1 - 0.42 9.2 7.1 0.53 8.9 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sporozoite_P67 PF05642.6 KFH41368.1 - 3.6 5.3 9.5 8.8 4.0 6.3 1.6 1 1 1 2 2 2 0 Sporozoite P67 surface antigen adh_short PF00106.20 KFH41369.1 - 1.1e-15 57.9 0.0 1.6e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH41369.1 - 4e-10 39.8 0.0 6.5e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH41369.1 - 9.5e-08 31.9 0.0 1.5e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFH41369.1 - 0.0031 16.9 0.0 0.0053 16.2 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 KFH41369.1 - 0.012 15.2 0.1 0.025 14.2 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KFH41369.1 - 0.047 12.8 0.0 0.091 11.9 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Zn_clus PF00172.13 KFH41370.1 - 1.1e-07 31.5 7.8 1.9e-07 30.8 5.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFH41370.1 - 3.9e-05 22.4 0.2 5.9e-05 21.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain HLH PF00010.21 KFH41371.1 - 1.9e-11 43.4 0.7 5.1e-11 42.1 0.5 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain F-box PF00646.28 KFH41372.1 - 0.051 13.2 0.6 0.19 11.4 0.0 2.3 2 0 0 2 2 2 0 F-box domain Glutaredoxin PF00462.19 KFH41373.1 - 1.9e-15 56.5 0.1 5e-15 55.2 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin ADH_zinc_N PF00107.21 KFH41374.1 - 1.2e-07 31.3 0.0 2.3e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFH41374.1 - 0.00039 20.1 0.0 0.00088 19.0 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KFH41374.1 - 0.11 13.3 0.0 0.27 12.1 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase AP_endonuc_2 PF01261.19 KFH41375.1 - 4.5e-29 101.2 0.0 6.1e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel WEMBL PF05701.6 KFH41376.1 - 6.5e-06 24.8 15.1 6.5e-06 24.8 10.4 1.9 1 1 1 2 2 2 1 Weak chloroplast movement under blue light Reo_sigmaC PF04582.7 KFH41376.1 - 1.3e-05 24.5 10.6 5.5e-05 22.5 2.6 2.1 1 1 1 2 2 2 1 Reovirus sigma C capsid protein Myosin_tail_1 PF01576.14 KFH41376.1 - 3.5e-05 21.7 20.1 9.8e-05 20.2 13.9 1.7 1 1 0 1 1 1 1 Myosin tail AAA_13 PF13166.1 KFH41376.1 - 0.00045 18.8 5.6 0.00072 18.1 3.9 1.2 1 0 0 1 1 1 1 AAA domain IFT57 PF10498.4 KFH41376.1 - 0.0023 16.7 10.6 0.1 11.3 0.3 2.2 1 1 1 2 2 2 2 Intra-flagellar transport protein 57 IncA PF04156.9 KFH41376.1 - 0.0033 17.0 23.0 0.27 10.7 5.1 3.0 1 1 1 2 2 2 2 IncA protein DUF972 PF06156.8 KFH41376.1 - 0.0033 17.7 9.4 0.2 12.0 2.2 3.3 2 1 1 3 3 3 1 Protein of unknown function (DUF972) Spc7 PF08317.6 KFH41376.1 - 0.0078 14.9 14.6 0.006 15.2 6.7 2.4 1 1 1 2 2 2 1 Spc7 kinetochore protein Filament PF00038.16 KFH41376.1 - 0.013 15.0 18.1 0.1 12.0 7.0 2.5 2 1 1 3 3 3 0 Intermediate filament protein Laminin_II PF06009.7 KFH41376.1 - 0.015 15.1 12.5 0.82 9.4 2.0 3.2 2 1 0 3 3 3 0 Laminin Domain II Cast PF10174.4 KFH41376.1 - 0.021 12.8 16.8 0.12 10.3 11.4 2.1 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone EzrA PF06160.7 KFH41376.1 - 0.026 12.7 10.5 0.75 7.9 0.3 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA ATG16 PF08614.6 KFH41376.1 - 0.034 13.9 17.9 0.043 13.6 6.7 2.9 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Snapin_Pallidin PF14712.1 KFH41376.1 - 0.045 14.0 13.6 1.1 9.6 0.2 4.1 3 1 1 4 4 4 0 Snapin/Pallidin Tropomyosin PF00261.15 KFH41376.1 - 0.051 12.6 14.7 0.089 11.8 10.2 1.3 1 0 0 1 1 1 0 Tropomyosin APG6 PF04111.7 KFH41376.1 - 0.056 12.4 13.3 0.19 10.7 6.1 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 Spectrin PF00435.16 KFH41376.1 - 0.078 13.2 8.3 0.18 12.1 0.1 3.4 3 1 0 3 3 3 0 Spectrin repeat GAS PF13851.1 KFH41376.1 - 0.12 11.5 13.7 0.044 12.9 0.8 2.7 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 KFH41376.1 - 0.14 11.9 15.9 1.6 8.4 0.8 3.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 KFH41376.1 - 0.14 11.9 19.0 0.34 10.7 3.1 3.4 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.4 KFH41376.1 - 0.17 10.7 15.9 0.086 11.7 8.1 2.1 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Sec8_exocyst PF04048.9 KFH41376.1 - 0.18 11.4 5.5 2.1 7.9 2.8 2.4 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain TMF_TATA_bd PF12325.3 KFH41376.1 - 0.21 11.3 20.2 0.14 11.9 3.8 3.8 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding Cortex-I_coil PF09304.5 KFH41376.1 - 0.29 11.1 14.6 0.028 14.4 4.6 2.9 1 1 1 2 2 2 0 Cortexillin I, coiled coil FUSC PF04632.7 KFH41376.1 - 0.3 9.4 9.0 0.41 9.0 6.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Occludin_ELL PF07303.8 KFH41376.1 - 0.3 11.8 6.9 24 5.7 0.2 4.1 1 1 3 4 4 4 0 Occludin homology domain Kinesin-relat_1 PF12711.2 KFH41376.1 - 0.32 11.4 13.1 4.7 7.6 1.9 4.0 2 1 2 4 4 4 0 Kinesin motor DUF1319 PF07028.6 KFH41376.1 - 0.51 10.5 11.6 3.5 7.8 0.1 3.6 2 1 3 5 5 4 0 Protein of unknown function (DUF1319) DUF745 PF05335.8 KFH41376.1 - 0.63 9.5 10.7 0.32 10.4 2.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF745) LXG PF04740.7 KFH41376.1 - 0.72 9.6 7.2 12 5.6 0.1 2.4 1 1 1 2 2 2 0 LXG domain of WXG superfamily TMCO5 PF14992.1 KFH41376.1 - 0.76 8.8 9.1 1.2 8.2 6.3 1.4 1 0 0 1 1 1 0 TMCO5 family Med4 PF10018.4 KFH41376.1 - 0.94 8.8 10.0 2.5 7.4 3.6 2.8 1 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 NYD-SP28 PF14772.1 KFH41376.1 - 1 9.4 8.7 0.46 10.6 0.1 2.9 2 1 0 2 2 2 0 Sperm tail DivIC PF04977.10 KFH41376.1 - 1.1 8.7 17.1 12 5.4 0.9 5.0 4 1 1 5 5 5 0 Septum formation initiator Mnd1 PF03962.10 KFH41376.1 - 1.4 8.5 14.4 6.5 6.3 2.2 3.1 2 1 1 3 3 3 0 Mnd1 family Fib_alpha PF08702.5 KFH41376.1 - 1.8 8.6 11.8 0.54 10.3 2.3 3.1 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.3 KFH41376.1 - 1.9 5.7 18.0 1 6.6 10.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Prominin PF05478.6 KFH41376.1 - 2.1 5.7 8.0 6.2 4.2 0.2 2.1 1 1 1 2 2 2 0 Prominin DUF4200 PF13863.1 KFH41376.1 - 2.4 8.1 17.6 0.18 11.7 0.8 3.6 2 1 0 3 3 3 0 Domain of unknown function (DUF4200) HAUS6_N PF14661.1 KFH41376.1 - 3.6 6.8 11.7 8.2 5.7 2.4 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Nup54 PF13874.1 KFH41376.1 - 3.7 7.2 11.8 0.59 9.8 4.7 2.2 2 1 1 3 3 2 0 Nucleoporin complex subunit 54 Cluap1 PF10234.4 KFH41376.1 - 3.8 6.6 13.8 0.34 10.0 0.9 2.6 1 1 1 2 2 2 0 Clusterin-associated protein-1 DUF342 PF03961.8 KFH41376.1 - 4.7 5.5 6.1 4.4 5.6 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Med9 PF07544.8 KFH41376.1 - 5 6.9 9.5 0.38 10.5 0.2 3.5 4 1 0 4 4 3 0 RNA polymerase II transcription mediator complex subunit 9 COG2 PF06148.6 KFH41376.1 - 5.4 6.8 13.3 0.89 9.4 0.3 3.3 2 1 1 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 AATF-Che1 PF13339.1 KFH41376.1 - 6.1 7.0 11.8 4 7.5 1.5 2.9 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor G-gamma PF00631.17 KFH41376.1 - 6.8 6.5 8.4 79 3.1 0.1 4.2 4 0 0 4 4 4 0 GGL domain V_ATPase_I PF01496.14 KFH41376.1 - 8 4.1 8.0 27 2.4 4.0 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Dzip-like_N PF13815.1 KFH41376.1 - 8.1 6.2 8.2 6 6.6 0.1 3.2 2 1 2 4 4 4 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal TBPIP PF07106.8 KFH41376.1 - 9.2 5.7 11.0 7.6 6.0 0.7 3.2 1 1 3 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) RNase_T PF00929.19 KFH41379.1 - 1.1e-25 90.8 0.0 1.6e-25 90.3 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Methyltransf_23 PF13489.1 KFH41380.1 - 2.6e-12 46.7 0.0 4.6e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH41380.1 - 0.00032 21.1 0.0 0.0029 18.0 0.0 2.3 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH41380.1 - 0.00074 19.9 0.0 0.018 15.4 0.0 2.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH41380.1 - 0.0019 18.7 0.0 0.012 16.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH41380.1 - 0.0048 16.5 0.0 0.59 9.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFH41380.1 - 0.016 15.5 0.0 0.13 12.5 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.13 KFH41380.1 - 0.036 13.1 0.0 4.2 6.4 0.0 2.2 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Ribosomal_60s PF00428.14 KFH41380.1 - 0.85 10.0 11.4 1.3 9.5 4.0 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein SDF PF00375.13 KFH41381.1 - 3.6e-92 309.1 35.1 4.5e-92 308.8 24.3 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family FCH PF00611.18 KFH41382.1 - 1.9e-23 82.4 1.6 2.4e-23 82.1 0.1 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 KFH41382.1 - 1.3e-12 46.9 0.0 2.3e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFH41382.1 - 3.5e-12 45.6 0.0 2.2e-11 43.0 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 KFH41382.1 - 1.7e-11 43.4 0.0 3.9e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Syntaxin PF00804.20 KFH41382.1 - 0.072 13.2 4.6 0.19 11.9 3.2 1.7 1 0 0 1 1 1 0 Syntaxin PhzC-PhzF PF02567.11 KFH41383.1 - 1.5e-37 129.3 0.2 1.1e-36 126.5 0.2 1.9 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Homeobox_KN PF05920.6 KFH41383.1 - 0.073 12.7 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Homeobox KN domain Pkinase PF00069.20 KFH41384.1 - 1e-70 237.8 0.0 1.3e-70 237.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH41384.1 - 5.2e-32 110.9 0.0 6.5e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH41384.1 - 0.0075 15.2 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFH41384.1 - 0.026 14.2 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KFH41384.1 - 0.043 12.8 0.1 0.13 11.3 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KFH41384.1 - 0.075 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RCC1 PF00415.13 KFH41385.1 - 1.1e-25 89.5 0.2 9.7e-07 28.9 0.3 5.1 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 KFH41385.1 - 2e-11 43.8 0.0 3.8e-08 33.2 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain RCC1_2 PF13540.1 KFH41385.1 - 5.3e-08 32.2 0.5 5.3e-08 32.2 0.3 4.7 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.1 KFH41385.1 - 7.9e-08 32.6 0.1 2.6e-06 27.7 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFH41385.1 - 0.0025 17.9 0.1 4.3 7.8 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KFH41385.1 - 0.0081 16.4 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) ATG16 PF08614.6 KFH41386.1 - 0.0011 18.8 0.7 0.002 17.9 0.5 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) ATG13 PF10033.4 KFH41387.1 - 3.2e-64 216.5 0.0 5.1e-64 215.8 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 VHS PF00790.14 KFH41388.1 - 1.3e-37 128.5 0.2 3.2e-37 127.2 0.1 1.6 1 0 0 1 1 1 1 VHS domain SH3_9 PF14604.1 KFH41388.1 - 7.5e-17 60.6 0.2 1.6e-16 59.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFH41388.1 - 1.9e-16 59.1 0.3 4.5e-16 57.9 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 KFH41388.1 - 1.3e-13 50.1 0.0 2.7e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.9 KFH41388.1 - 0.018 15.0 0.9 0.06 13.3 0.6 1.9 1 0 0 1 1 1 0 GAT domain TIR PF01582.15 KFH41388.1 - 0.046 13.1 0.4 0.3 10.5 0.1 2.2 2 0 0 2 2 2 0 TIR domain UIM PF02809.15 KFH41388.1 - 0.14 11.8 5.6 0.31 10.7 3.9 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif E1-E2_ATPase PF00122.15 KFH41389.1 - 1.1e-51 175.1 0.1 2.3e-51 174.0 0.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KFH41389.1 - 9.7e-40 137.2 0.7 1.9e-39 136.2 0.5 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KFH41389.1 - 5e-23 81.0 1.1 9.8e-12 44.8 0.1 3.7 3 0 0 3 3 3 2 Heavy-metal-associated domain HAD PF12710.2 KFH41389.1 - 1.3e-15 58.0 0.0 2.5e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFH41389.1 - 3e-06 27.0 0.3 1.2e-05 25.0 0.2 1.9 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase DUF566 PF04484.7 KFH41390.1 - 1.7 8.0 10.6 3.2 7.1 7.4 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF566) TFIIF_alpha PF05793.7 KFH41390.1 - 2.7 6.2 9.0 4 5.6 6.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) UPF0029 PF01205.14 KFH41391.1 - 6.7e-26 90.1 0.0 1.4e-25 89.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 FAD_binding_1 PF00667.15 KFH41392.1 - 1e-64 218.0 0.0 2e-64 217.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KFH41392.1 - 1.9e-12 47.6 0.0 2.9e-11 43.8 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain POR PF01558.13 KFH41392.1 - 4.9e-08 33.0 0.2 1.6e-07 31.3 0.0 1.9 2 0 0 2 2 2 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 KFH41392.1 - 0.00024 21.0 0.4 0.00064 19.6 0.3 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Not1 PF04054.10 KFH41393.1 - 9.7e-89 297.8 0.0 1.9e-88 296.9 0.0 1.5 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 KFH41393.1 - 2.1e-46 157.2 0.9 6e-46 155.7 0.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) Cyclin_N PF00134.18 KFH41394.1 - 2.5e-15 56.1 0.0 4.1e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 KFH41394.1 - 1.4e-10 41.7 0.2 1.4e-10 41.7 0.1 1.8 2 1 0 2 2 2 1 Cyclin Mating_C PF12737.2 KFH41394.1 - 3.1 6.6 22.1 0.16 10.8 11.4 1.6 2 0 0 2 2 2 0 C-terminal domain of homeodomain 1 SNF2_N PF00176.18 KFH41396.1 - 2.2e-77 259.8 0.1 3.9e-77 259.0 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFH41396.1 - 1.8e-11 43.7 0.0 4.4e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFH41396.1 - 1.2e-06 28.0 0.0 4.3e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 KFH41396.1 - 0.00014 20.8 0.2 0.023 13.5 0.1 3.3 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 AAA PF00004.24 KFH41397.1 - 8.2e-38 129.5 0.0 1.4e-37 128.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFH41397.1 - 7.7e-07 29.3 0.1 0.001 19.1 0.0 3.4 3 1 1 4 4 4 1 AAA domain AAA_16 PF13191.1 KFH41397.1 - 1.7e-05 24.8 0.4 0.00044 20.2 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 KFH41397.1 - 2.1e-05 23.6 0.0 4.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KFH41397.1 - 2.3e-05 24.2 0.0 5.1e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFH41397.1 - 4e-05 23.3 0.1 0.00043 20.0 0.0 2.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KFH41397.1 - 5.8e-05 23.9 0.1 0.00023 21.9 0.0 2.1 2 1 0 2 2 1 1 AAA domain AAA_2 PF07724.9 KFH41397.1 - 6.1e-05 23.0 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 KFH41397.1 - 0.00034 20.0 0.0 0.0007 19.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 KFH41397.1 - 0.00083 19.4 0.0 0.0043 17.1 0.0 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.1 KFH41397.1 - 0.00089 19.1 1.4 0.0017 18.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KFH41397.1 - 0.0018 17.4 0.1 0.0039 16.3 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 KFH41397.1 - 0.0019 17.3 0.0 0.0041 16.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 KFH41397.1 - 0.0047 16.6 0.3 0.016 14.9 0.1 1.9 2 0 0 2 2 1 1 Part of AAA domain AAA_18 PF13238.1 KFH41397.1 - 0.0048 17.2 0.0 0.072 13.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KFH41397.1 - 0.0094 15.6 0.0 0.039 13.5 0.0 2.0 1 1 1 2 2 2 1 NACHT domain Sigma54_activat PF00158.21 KFH41397.1 - 0.011 15.2 0.0 0.033 13.6 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.1 KFH41397.1 - 0.011 15.6 0.3 0.036 14.0 0.0 2.0 3 0 0 3 3 1 0 AAA domain RNA_helicase PF00910.17 KFH41397.1 - 0.019 15.1 0.0 0.043 14.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 KFH41397.1 - 0.022 14.1 4.4 0.27 10.6 0.1 2.9 2 1 0 3 3 3 0 AAA domain DUF815 PF05673.8 KFH41397.1 - 0.024 13.5 0.0 0.043 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Oxidored_nitro PF00148.14 KFH41397.1 - 0.025 13.2 0.0 0.22 10.1 0.0 2.0 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase AAA_10 PF12846.2 KFH41397.1 - 0.041 13.3 0.5 1 8.7 0.0 2.8 2 1 0 3 3 3 0 AAA-like domain ABC_tran PF00005.22 KFH41397.1 - 0.048 13.9 0.0 0.12 12.6 0.0 1.8 1 1 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 KFH41397.1 - 0.07 12.8 0.0 0.63 9.6 0.0 2.2 1 1 1 2 2 2 0 Archaeal ATPase TIP49 PF06068.8 KFH41397.1 - 0.079 11.6 0.1 0.15 10.7 0.0 1.5 1 1 0 1 1 1 0 TIP49 C-terminus NB-ARC PF00931.17 KFH41397.1 - 0.084 11.7 0.0 0.21 10.4 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain Rad17 PF03215.10 KFH41397.1 - 0.1 11.2 0.0 0.15 10.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_24 PF13479.1 KFH41397.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KFH41397.1 - 0.13 11.9 0.1 15 5.2 0.0 3.0 3 0 0 3 3 3 0 NTPase PhoH PF02562.11 KFH41397.1 - 0.14 11.3 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Guanylate_kin PF00625.16 KFH41397.1 - 0.16 11.4 0.0 0.84 9.0 0.0 2.2 2 1 0 2 2 2 0 Guanylate kinase Viral_helicase1 PF01443.13 KFH41397.1 - 0.17 11.3 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Pyr_redox_2 PF07992.9 KFH41398.1 - 1.1e-06 28.7 0.0 6.8e-06 26.1 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFH41398.1 - 5.1e-05 23.4 0.0 0.0035 17.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFH41398.1 - 0.021 14.8 0.0 0.063 13.3 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KFH41398.1 - 0.1 12.3 0.1 0.97 9.1 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.9 KFH41398.1 - 0.14 10.5 0.0 1.2 7.4 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein PGAP1 PF07819.8 KFH41399.1 - 1.9e-89 299.0 0.0 3e-89 298.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KFH41399.1 - 5.7e-06 26.1 0.0 1.2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFH41399.1 - 1.9e-05 24.6 0.1 4e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KFH41399.1 - 0.021 14.1 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.15 KFH41399.1 - 0.032 13.7 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold LCAT PF02450.10 KFH41399.1 - 0.061 12.2 0.0 0.094 11.6 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Esterase PF00756.15 KFH41399.1 - 0.09 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative esterase COesterase PF00135.23 KFH41399.1 - 0.11 11.1 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family MutL_C PF08676.6 KFH41400.1 - 7.2e-21 74.2 0.0 1.5e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 KFH41400.1 - 7.7e-19 67.3 0.0 3.5e-18 65.2 0.0 2.2 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KFH41400.1 - 3.9e-14 52.4 0.1 1.1e-13 50.9 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KFH41400.1 - 3.1e-11 42.9 0.0 6.7e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CENP-B_dimeris PF09026.5 KFH41400.1 - 7.9 6.7 19.5 0.064 13.4 4.5 3.2 3 0 0 3 3 3 0 Centromere protein B dimerisation domain CAP_N PF01213.14 KFH41401.1 - 9e-98 327.4 0.2 1.4e-97 326.7 0.1 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 KFH41401.1 - 4.8e-56 188.5 3.0 6.5e-56 188.0 2.1 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 KFH41401.1 - 0.23 10.8 1.2 0.69 9.3 0.8 1.7 1 1 0 1 1 1 0 Tubulin binding cofactor C Ribosomal_60s PF00428.14 KFH41401.1 - 3.6 8.0 10.1 3.4 8.1 0.3 3.3 3 0 0 3 3 3 0 60s Acidic ribosomal protein SWIRM PF04433.12 KFH41402.1 - 7.3e-35 118.9 0.1 1.3e-34 118.1 0.1 1.5 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 KFH41402.1 - 1.7e-07 31.1 0.0 3.4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFH41402.1 - 3.2e-06 27.1 0.4 7.2e-06 26.0 0.3 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 KFH41402.1 - 0.0014 18.1 4.5 0.0028 17.1 3.1 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type FmrO PF07091.6 KFH41402.1 - 0.052 12.5 0.0 0.099 11.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) DUF3439 PF11921.3 KFH41402.1 - 0.17 11.6 5.3 0.21 11.3 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) ATP_synt_H PF05493.8 KFH41403.1 - 6e-09 35.8 0.1 6.5e-09 35.7 0.0 1.0 1 0 0 1 1 1 1 ATP synthase subunit H Fungal_trans PF04082.13 KFH41404.1 - 2e-35 121.9 0.0 5.6e-35 120.4 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH41404.1 - 0.00025 20.8 1.1 0.00042 20.1 0.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CD24 PF14984.1 KFH41404.1 - 0.11 12.3 7.2 0.3 10.9 5.0 1.7 1 0 0 1 1 1 0 CD24 protein Arv1 PF04161.8 KFH41405.1 - 1.8e-46 158.6 0.0 2.4e-46 158.3 0.0 1.1 1 0 0 1 1 1 1 Arv1-like family ETF PF01012.16 KFH41406.1 - 3.6e-39 134.1 1.5 4.8e-39 133.7 0.3 1.8 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 KFH41406.1 - 5.9e-36 121.9 0.2 1.4e-35 120.7 0.1 1.7 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain MFS_1 PF07690.11 KFH41407.1 - 3.1e-21 75.5 26.4 1.8e-18 66.4 17.5 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 KFH41407.1 - 3.4e-12 46.1 1.1 3.4e-12 46.1 0.8 2.3 2 0 0 2 2 2 1 Nodulin-like MFS_2 PF13347.1 KFH41407.1 - 0.0031 15.9 2.1 0.0031 15.9 1.5 2.4 2 1 0 2 2 2 1 MFS/sugar transport protein Spore_permease PF03845.8 KFH41408.1 - 0.13 10.8 0.2 0.21 10.2 0.1 1.2 1 0 0 1 1 1 0 Spore germination protein DUF4234 PF14018.1 KFH41408.1 - 0.19 11.4 0.5 0.44 10.3 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) PfkB PF00294.19 KFH41409.1 - 4e-14 52.4 0.0 3.7e-09 36.1 0.0 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Carn_acyltransf PF00755.15 KFH41410.1 - 4.7e-181 602.8 0.0 5.4e-181 602.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Cys_Met_Meta_PP PF01053.15 KFH41411.1 - 1.7e-137 457.8 0.1 2e-137 457.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KFH41411.1 - 4.5e-06 25.8 0.0 1.1e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KFH41411.1 - 5.5e-06 25.6 0.2 1e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 KFH41411.1 - 1.3e-05 24.1 0.2 2.8e-05 23.0 0.1 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Met_gamma_lyase PF06838.6 KFH41411.1 - 2.9e-05 22.5 0.2 8.3e-05 21.0 0.1 1.6 1 1 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 KFH41411.1 - 4.7e-05 22.2 0.2 9.4e-05 21.2 0.1 1.4 1 1 0 1 1 1 1 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 KFH41411.1 - 0.00035 19.7 0.3 0.00095 18.3 0.2 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase POTRA_2 PF08479.6 KFH41411.1 - 0.037 13.6 0.0 0.13 11.9 0.0 1.9 1 0 0 1 1 1 0 POTRA domain, ShlB-type 2_5_RNA_ligase2 PF13563.1 KFH41412.1 - 1.2e-31 109.4 0.6 6.2e-30 103.9 0.2 2.4 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily PAP_central PF04928.12 KFH41412.1 - 6.2e-15 54.7 0.0 1.5e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Poly(A) polymerase central domain Exo_endo_phos PF03372.18 KFH41412.1 - 3.7e-14 53.2 0.1 7.8e-14 52.2 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF504 PF04457.7 KFH41412.1 - 1.1e-10 41.4 1.9 3.3e-10 39.9 1.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF504) PAP_RNA-bind PF04926.10 KFH41412.1 - 0.00017 21.1 0.0 0.00027 20.4 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain Retinal PF15449.1 KFH41412.1 - 0.48 8.0 0.3 0.68 7.5 0.2 1.1 1 0 0 1 1 1 0 Retinal protein Nop14 PF04147.7 KFH41412.1 - 1.2 7.0 1.3 1.6 6.5 0.9 1.1 1 0 0 1 1 1 0 Nop14-like family PBP1_TM PF14812.1 KFH41412.1 - 4.6 7.6 6.6 9.7 6.5 4.6 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CobT PF06213.7 KFH41412.1 - 5.8 5.9 8.2 9.3 5.2 5.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DNA_pol_phi PF04931.8 KFH41412.1 - 6.6 4.3 10.3 9.5 3.8 7.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Exo70 PF03081.10 KFH41413.1 - 3.1e-75 253.2 0.0 4.7e-75 252.6 0.0 1.2 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Baculo_PEP_C PF04513.7 KFH41413.1 - 0.031 14.1 2.2 0.8 9.5 0.0 3.2 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus K-box PF01486.12 KFH41413.1 - 0.031 14.0 0.8 1.1 9.0 0.0 3.3 3 0 0 3 3 3 0 K-box region Apolipoprotein PF01442.13 KFH41413.1 - 0.056 12.9 1.1 0.83 9.1 0.0 3.0 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain PigN PF04987.9 KFH41414.1 - 1.6e-158 528.0 29.9 2e-158 527.7 20.7 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 KFH41414.1 - 3.2e-10 39.9 1.6 8.8e-09 35.1 1.1 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KFH41414.1 - 1.2e-06 27.9 0.2 5.5e-06 25.7 0.1 2.0 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.13 KFH41414.1 - 0.0066 15.8 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily LysM PF01476.15 KFH41415.1 - 0.015 15.1 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 LysM domain Csm1 PF12539.3 KFH41416.1 - 9.2e-26 90.1 0.0 2.1e-25 89.0 0.0 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 DUF2353 PF09789.4 KFH41416.1 - 0.00065 19.0 4.9 0.0011 18.3 3.4 1.4 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) TPR_MLP1_2 PF07926.7 KFH41416.1 - 0.00081 19.1 13.7 0.0028 17.3 9.2 2.0 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein PspA_IM30 PF04012.7 KFH41416.1 - 0.0041 16.5 8.8 0.0085 15.4 6.1 1.5 1 0 0 1 1 1 1 PspA/IM30 family Spc7 PF08317.6 KFH41416.1 - 0.0062 15.2 7.9 0.011 14.4 5.5 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein IncA PF04156.9 KFH41416.1 - 0.0082 15.7 15.1 0.046 13.3 10.5 2.0 1 1 0 1 1 1 1 IncA protein AAA_13 PF13166.1 KFH41416.1 - 0.012 14.0 4.9 0.016 13.6 3.4 1.1 1 0 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 KFH41416.1 - 0.059 12.5 5.2 0.27 10.3 3.5 1.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Exonuc_VII_L PF02601.10 KFH41416.1 - 0.062 12.4 4.9 0.094 11.8 3.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-F_leu_zip PF10473.4 KFH41416.1 - 0.071 12.9 15.7 0.45 10.3 2.3 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.5 KFH41416.1 - 0.075 13.1 4.5 0.17 12.0 3.1 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family APG6 PF04111.7 KFH41416.1 - 0.094 11.7 7.7 0.16 11.0 5.3 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Lge1 PF11488.3 KFH41416.1 - 0.13 12.4 4.5 0.27 11.4 0.0 2.8 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 Syntaxin PF00804.20 KFH41416.1 - 0.17 12.0 6.7 0.41 10.8 4.6 1.7 1 0 0 1 1 1 0 Syntaxin Spt5_N PF11942.3 KFH41416.1 - 0.18 12.4 9.9 0.56 10.8 6.8 1.9 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal SlyX PF04102.7 KFH41416.1 - 0.2 12.0 4.4 0.97 9.8 0.2 3.3 1 1 1 3 3 3 0 SlyX FemAB PF02388.11 KFH41416.1 - 0.21 10.2 2.6 0.33 9.5 1.8 1.3 1 0 0 1 1 1 0 FemAB family Sec8_exocyst PF04048.9 KFH41416.1 - 0.27 10.8 3.9 0.52 9.9 2.7 1.5 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain THOC7 PF05615.8 KFH41416.1 - 0.28 11.4 8.8 0.84 9.9 6.1 1.6 1 1 0 1 1 1 0 Tho complex subunit 7 DUF2968 PF11180.3 KFH41416.1 - 0.32 10.3 9.8 0.57 9.5 6.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Prefoldin_2 PF01920.15 KFH41416.1 - 0.37 10.5 10.1 3.6 7.3 0.3 3.4 1 1 2 3 3 3 0 Prefoldin subunit ADIP PF11559.3 KFH41416.1 - 0.38 10.6 16.3 0.23 11.3 7.6 2.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Adeno_PIX PF03955.9 KFH41416.1 - 0.39 11.2 6.5 0.9 10.0 4.0 2.0 2 0 0 2 2 1 0 Adenovirus hexon-associated protein (IX) Atg14 PF10186.4 KFH41416.1 - 0.4 9.5 11.9 0.65 8.8 8.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AT_hook PF02178.14 KFH41416.1 - 0.4 10.5 21.6 0.16 11.7 0.3 3.8 3 0 0 3 3 3 0 AT hook motif DUF4618 PF15397.1 KFH41416.1 - 0.46 9.7 7.7 1.1 8.4 5.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) DUF2730 PF10805.3 KFH41416.1 - 0.54 10.0 2.5 0.34 10.6 0.3 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF2730) TMPIT PF07851.8 KFH41416.1 - 0.55 9.2 2.0 0.89 8.5 1.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein GAS PF13851.1 KFH41416.1 - 0.61 9.2 11.4 1.1 8.3 5.3 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FliJ PF02050.11 KFH41416.1 - 0.79 9.7 9.1 2.3 8.3 6.3 1.8 1 1 0 1 1 1 0 Flagellar FliJ protein MscS_porin PF12795.2 KFH41416.1 - 0.97 8.6 17.0 0.75 9.0 9.6 2.1 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Baculo_PEP_C PF04513.7 KFH41416.1 - 1.1 9.1 5.8 2.5 7.9 4.0 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bap31 PF05529.7 KFH41416.1 - 1.5 8.2 8.0 0.66 9.4 3.4 1.9 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like ATG16 PF08614.6 KFH41416.1 - 1.5 8.5 14.7 1.1 8.9 5.3 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Kinetocho_Slk19 PF12709.2 KFH41416.1 - 1.6 8.8 8.0 0.78 9.8 0.2 2.8 1 1 1 2 2 2 0 Central kinetochore-associated ERM PF00769.14 KFH41416.1 - 1.6 8.1 16.1 0.31 10.5 8.3 1.8 1 1 1 2 2 2 0 Ezrin/radixin/moesin family TACC PF05010.9 KFH41416.1 - 1.9 8.2 12.2 4.5 6.9 8.4 1.8 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) TBPIP PF07106.8 KFH41416.1 - 1.9 8.0 9.9 1.5 8.3 3.7 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) V_ATPase_I PF01496.14 KFH41416.1 - 2 6.1 11.2 11 3.6 0.0 2.8 2 1 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF3138 PF11336.3 KFH41416.1 - 2.7 6.0 5.2 3.7 5.6 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Syntaxin-6_N PF09177.6 KFH41416.1 - 2.9 8.3 8.5 5.4 7.4 2.6 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Nup54 PF13874.1 KFH41416.1 - 3.7 7.1 9.7 4 7.1 0.7 2.5 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 HALZ PF02183.13 KFH41416.1 - 4 7.2 13.2 1.8 8.3 0.5 3.6 3 1 0 3 3 3 0 Homeobox associated leucine zipper FUSC PF04632.7 KFH41416.1 - 4.3 5.6 5.9 5.9 5.1 4.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family TMF_DNA_bd PF12329.3 KFH41416.1 - 5.2 6.9 16.4 5.5 6.8 1.5 3.5 1 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DivIVA PF05103.8 KFH41416.1 - 7.5 6.6 12.5 3.9 7.5 1.6 2.7 1 1 1 2 2 2 0 DivIVA protein CDC37_N PF03234.9 KFH41416.1 - 9.2 6.5 10.6 0.69 10.2 3.9 1.7 2 0 0 2 2 1 0 Cdc37 N terminal kinase binding MCM PF00493.18 KFH41417.1 - 5.3e-129 429.7 0.2 7.8e-129 429.2 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KFH41417.1 - 4.2e-18 65.9 0.2 2.3e-17 63.5 0.0 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KFH41417.1 - 3.9e-07 29.4 0.0 4.8e-06 25.8 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KFH41417.1 - 0.0072 15.9 0.0 0.018 14.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KFH41417.1 - 0.0095 15.4 0.0 0.029 13.8 0.0 1.7 2 0 0 2 2 2 1 Sigma-54 interaction domain TFIIF_alpha PF05793.7 KFH41417.1 - 5.2 5.3 11.0 7.8 4.7 7.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Serinc PF03348.10 KFH41418.1 - 6.7e-175 581.9 9.5 7.7e-175 581.7 6.6 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) HC2 PF07382.6 KFH41419.1 - 0.14 11.9 17.9 0.25 11.1 12.4 1.5 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Sugar_tr PF00083.19 KFH41420.1 - 2e-71 240.9 20.6 2.2e-71 240.7 14.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH41420.1 - 5.5e-21 74.6 51.2 9e-15 54.2 17.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC2_membrane_2 PF12679.2 KFH41420.1 - 0.051 12.4 11.0 0.013 14.3 4.9 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein Pkinase PF00069.20 KFH41421.1 - 6.3e-05 22.2 0.0 9.7e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH41421.1 - 0.00052 19.1 0.0 0.0011 18.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase PIG-L PF02585.12 KFH41422.1 - 2.2e-26 92.8 0.0 3.4e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase RBP_receptor PF14752.1 KFH41424.1 - 0.043 12.1 0.2 0.078 11.2 0.1 1.4 1 0 0 1 1 1 0 Retinol binding protein receptor KdpA PF03814.10 KFH41425.1 - 0.22 9.4 0.7 0.34 8.8 0.5 1.2 1 0 0 1 1 1 0 Potassium-transporting ATPase A subunit Glyco_hydro_61 PF03443.9 KFH41426.1 - 3.5e-27 95.6 0.2 2.4e-25 89.6 0.2 2.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 Luciferase_cat PF10285.4 KFH41426.1 - 0.074 12.2 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Luciferase catalytic domain PRANC PF09372.5 KFH41427.1 - 0.028 14.4 0.0 0.065 13.2 0.0 1.6 1 0 0 1 1 1 0 PRANC domain Aldedh PF00171.17 KFH41429.1 - 2.2e-151 504.3 0.1 2.5e-151 504.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Bac_rhodopsin PF01036.13 KFH41430.1 - 3.2e-24 85.4 31.3 3.7e-16 59.0 16.0 2.0 2 0 0 2 2 2 2 Bacteriorhodopsin-like protein Iso_dh PF00180.15 KFH41431.1 - 2.8e-113 378.4 0.0 3.2e-113 378.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase BNR_2 PF13088.1 KFH41434.1 - 3.8e-35 121.5 0.6 4.7e-35 121.2 0.4 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR_3 PF13859.1 KFH41434.1 - 2.1e-10 40.2 0.0 3.3e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 BNR repeat-like domain adh_short_C2 PF13561.1 KFH41436.1 - 2.3e-30 106.1 0.0 2.9e-30 105.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFH41436.1 - 6.6e-29 100.9 0.2 8.3e-29 100.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH41436.1 - 5e-09 36.0 0.0 7.5e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFH41436.1 - 0.0014 18.0 0.3 0.0039 16.6 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFH41436.1 - 0.021 14.8 0.1 0.033 14.2 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding 3HCDH_N PF02737.13 KFH41436.1 - 0.037 13.6 0.1 0.053 13.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 KFH41436.1 - 0.039 13.7 1.3 0.083 12.6 0.9 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase APH PF01636.18 KFH41437.1 - 2.4e-09 37.2 0.1 3.7e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFH41437.1 - 1.4e-05 24.8 0.0 8.4e-05 22.2 0.0 1.9 1 1 0 1 1 1 1 Choline/ethanolamine kinase Fungal_trans PF04082.13 KFH41438.1 - 2.7e-21 75.6 1.6 4e-21 75.0 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 KFH41438.1 - 2.8e-08 33.5 15.4 0.00015 21.8 0.4 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KFH41438.1 - 2.7e-07 30.5 15.0 0.00058 20.0 3.4 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KFH41438.1 - 0.0032 17.3 0.6 1.5 8.8 0.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFH41438.1 - 0.0064 16.6 0.1 0.044 13.9 0.1 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFH41438.1 - 0.014 15.6 2.8 0.35 11.1 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KFH41438.1 - 0.44 10.6 5.3 6.7 6.9 3.9 2.5 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 KFH41438.1 - 0.89 9.9 12.6 0.65 10.3 1.6 3.9 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2HC_2 PF13913.1 KFH41438.1 - 1.4 8.6 7.2 0.8 9.4 1.5 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-RING_3 PF14369.1 KFH41438.1 - 4.1 7.4 6.4 12 5.9 0.1 3.5 3 0 0 3 3 3 0 zinc-finger IncA PF04156.9 KFH41439.1 - 0.0011 18.5 0.3 0.0019 17.8 0.2 1.3 1 0 0 1 1 1 1 IncA protein Na_H_Exchanger PF00999.16 KFH41440.1 - 4.3e-66 222.9 23.4 5.2e-66 222.7 16.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Nha1_C PF08619.5 KFH41440.1 - 2.3e-63 214.9 21.0 2.8e-63 214.7 14.6 1.1 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Holin_BlyA PF05102.7 KFH41440.1 - 0.75 9.5 1.6 1.9 8.2 1.1 1.6 1 0 0 1 1 1 0 holin, BlyA family YrhC PF14143.1 KFH41440.1 - 1.4 8.9 5.6 0.47 10.4 0.2 2.7 3 0 0 3 3 3 0 YrhC-like protein Cyclase PF04199.8 KFH41441.1 - 2.3e-10 40.4 0.0 3.4e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Cupin_3 PF05899.7 KFH41441.1 - 0.05 12.9 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) SecY PF00344.15 KFH41442.1 - 7.1e-93 311.2 12.9 1.1e-92 310.6 8.9 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 KFH41442.1 - 1.2e-16 59.8 0.1 5.4e-16 57.7 0.2 2.1 2 0 0 2 2 2 1 Plug domain of Sec61p Phage_holin_1 PF04531.8 KFH41442.1 - 0.84 9.7 3.6 6.8 6.8 0.1 3.7 3 1 1 4 4 4 0 Bacteriophage holin Fungal_trans PF04082.13 KFH41443.1 - 9.9e-19 67.2 0.3 1.5e-17 63.3 0.2 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH41443.1 - 7.4e-09 35.3 9.1 1.2e-08 34.6 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sdh_cyt PF01127.17 KFH41444.1 - 3.2e-19 68.9 4.3 4.2e-19 68.5 3.0 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit CorA PF01544.13 KFH41445.1 - 8.2e-12 44.7 3.4 3e-11 42.9 0.6 2.2 1 1 1 2 2 2 1 CorA-like Mg2+ transporter protein DUF676 PF05057.9 KFH41445.1 - 5.5e-06 25.8 0.0 9.9e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Cutinase PF01083.17 KFH41445.1 - 0.02 14.6 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Cutinase Abhydrolase_5 PF12695.2 KFH41445.1 - 0.021 14.5 0.0 0.053 13.2 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.20 KFH41445.1 - 0.042 13.4 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 KFH41445.1 - 0.17 11.4 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein EMP70 PF02990.11 KFH41445.1 - 0.93 7.8 0.0 1.4 7.2 0.0 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 Ribosomal_L27 PF01016.14 KFH41446.1 - 8.9e-23 79.8 0.1 1.6e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal L27 protein E1-E2_ATPase PF00122.15 KFH41447.1 - 2.4e-18 66.0 0.1 6e-18 64.7 0.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KFH41447.1 - 1.6e-14 54.8 0.0 5.9e-13 49.7 0.0 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFH41447.1 - 9.5e-12 45.4 3.5 6.7e-11 42.7 2.4 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFH41447.1 - 1.7e-10 40.7 0.0 5.5e-10 39.0 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFH41447.1 - 0.00088 18.9 0.4 0.049 13.2 0.0 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Poxvirus_B22R PF04395.7 KFH41447.1 - 0.031 13.7 4.3 1.9 7.9 0.0 2.5 2 0 0 2 2 2 0 Poxvirus B22R protein Adaptin_binding PF10199.4 KFH41448.1 - 3.5e-11 43.5 3.2 7.8e-11 42.4 2.2 1.6 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 NdhL PF10716.4 KFH41448.1 - 0.22 11.3 4.4 0.43 10.3 3.1 1.4 1 0 0 1 1 1 0 NADH dehydrogenase transmembrane subunit ABC_tran PF00005.22 KFH41449.1 - 9.5e-52 174.9 0.0 1.8e-31 109.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KFH41449.1 - 7.7e-38 130.4 35.5 5.3e-26 91.6 4.7 3.9 4 1 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.14 KFH41449.1 - 2.9e-08 33.2 0.2 0.021 14.0 0.0 4.1 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KFH41449.1 - 1e-06 29.2 0.1 0.0022 18.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 KFH41449.1 - 3.1e-06 27.3 0.0 1.3 8.9 0.0 3.7 2 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 KFH41449.1 - 4.5e-06 26.1 0.1 0.12 11.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain T2SE PF00437.15 KFH41449.1 - 0.00031 19.7 0.0 0.081 11.8 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.1 KFH41449.1 - 0.00034 20.0 0.7 0.83 9.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KFH41449.1 - 0.00042 20.3 0.5 0.055 13.4 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_10 PF12846.2 KFH41449.1 - 0.00065 19.2 0.2 0.12 11.8 0.0 2.9 2 1 0 3 3 3 1 AAA-like domain Zeta_toxin PF06414.7 KFH41449.1 - 0.00069 18.7 0.8 0.76 8.8 0.1 2.5 2 0 0 2 2 2 2 Zeta toxin DUF258 PF03193.11 KFH41449.1 - 0.0038 16.4 0.0 2.3 7.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF87 PF01935.12 KFH41449.1 - 0.0039 17.0 1.7 0.025 14.4 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function DUF87 MobB PF03205.9 KFH41449.1 - 0.0045 16.7 0.5 13 5.4 0.1 3.7 4 0 0 4 4 3 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KFH41449.1 - 0.01 15.8 0.0 0.12 12.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.1 KFH41449.1 - 0.019 15.7 0.0 14 6.5 0.0 3.1 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KFH41449.1 - 0.021 15.3 0.0 5 7.6 0.1 2.8 2 0 0 2 2 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 KFH41449.1 - 0.03 13.7 0.1 4.6 6.6 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family IstB_IS21 PF01695.12 KFH41449.1 - 0.034 13.5 0.0 1.6 8.0 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein TrwB_AAD_bind PF10412.4 KFH41449.1 - 0.047 12.3 1.2 3.7 6.0 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.1 KFH41449.1 - 0.063 13.4 1.4 29 4.7 0.0 3.6 2 1 0 2 2 2 0 AAA domain Ubie_methyltran PF01209.13 KFH41449.1 - 0.09 11.8 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family AAA_18 PF13238.1 KFH41449.1 - 0.11 12.7 0.1 23 5.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 KFH41449.1 - 0.13 11.8 0.7 3 7.4 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ResIII PF04851.10 KFH41449.1 - 0.23 11.2 0.1 11 5.7 0.0 2.6 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 KFH41449.1 - 0.24 10.9 0.0 4.7 6.7 0.0 2.8 2 1 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 KFH41449.1 - 0.84 8.8 2.0 25 4.0 0.1 3.0 3 0 0 3 3 3 0 Poxvirus A32 protein IPP-2 PF04979.9 KFH41451.1 - 4.5e-11 43.1 8.5 8.4e-07 29.2 0.2 2.5 3 0 0 3 3 3 2 Protein phosphatase inhibitor 2 (IPP-2) DUF2722 PF10846.3 KFH41451.1 - 0.001 18.1 1.9 0.0014 17.7 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF4658 PF15555.1 KFH41451.1 - 0.32 10.8 6.7 0.64 9.9 4.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) Homeobox PF00046.24 KFH41452.1 - 2.5e-19 68.6 4.3 5.2e-19 67.6 3.0 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFH41452.1 - 0.00074 19.1 0.3 0.0022 17.6 0.2 1.8 1 0 0 1 1 1 1 Homeobox KN domain IPPT PF01715.12 KFH41453.1 - 2.7e-56 190.4 0.2 4.1e-56 189.8 0.1 1.3 1 0 0 1 1 1 1 IPP transferase IPT PF01745.11 KFH41453.1 - 2.1e-06 27.0 0.0 4.5e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 Isopentenyl transferase AAA_33 PF13671.1 KFH41453.1 - 0.00023 21.0 0.4 0.012 15.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 KFH41453.1 - 0.00035 21.3 1.1 0.0017 19.1 0.6 2.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFH41453.1 - 0.00038 20.7 0.8 0.003 17.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain zf-met PF12874.2 KFH41453.1 - 0.0067 16.6 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFH41453.1 - 0.0093 16.0 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding RNA_helicase PF00910.17 KFH41453.1 - 0.019 15.1 0.1 0.16 12.1 0.0 2.2 2 0 0 2 2 2 0 RNA helicase Hpr_kinase_C PF07475.7 KFH41453.1 - 0.024 13.9 0.0 0.045 13.0 0.0 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain ABC_tran PF00005.22 KFH41453.1 - 0.028 14.7 0.1 0.28 11.4 0.0 2.6 2 1 0 2 2 2 0 ABC transporter AAA_5 PF07728.9 KFH41453.1 - 0.033 13.9 0.0 0.081 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KFH41453.1 - 0.046 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 KFH41453.1 - 0.071 13.0 0.6 0.23 11.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KFH41453.1 - 0.083 12.2 0.2 0.39 10.0 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.1 KFH41453.1 - 0.093 12.8 0.0 0.29 11.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.12 KFH41453.1 - 0.13 12.0 0.2 0.6 9.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 PPV_E1_C PF00519.12 KFH41453.1 - 0.18 10.3 0.0 0.3 9.6 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase DUF1546 PF07571.8 KFH41455.1 - 3e-25 88.1 0.0 6.4e-25 87.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 KFH41455.1 - 4e-22 77.9 0.2 6.5e-22 77.2 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 KFH41455.1 - 9.6e-05 22.4 0.5 0.00019 21.4 0.3 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 KFH41455.1 - 0.086 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated Cupin_3 PF05899.7 KFH41456.1 - 9.5e-07 28.1 0.4 2.7e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF861) AraC_binding PF02311.14 KFH41456.1 - 0.0011 18.7 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_2 PF07883.6 KFH41456.1 - 0.0023 17.4 0.0 0.0047 16.3 0.0 1.5 1 0 0 1 1 1 1 Cupin domain CENP-C_C PF11699.3 KFH41456.1 - 0.038 13.9 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 Mif2/CENP-C like Fels1 PF05666.6 KFH41457.1 - 0.31 10.4 1.3 0.37 10.2 0.3 1.6 2 0 0 2 2 2 0 Fels-1 Prophage Protein-like SNF PF00209.13 KFH41458.1 - 8.7e-79 265.3 39.4 3.8e-54 184.0 10.7 2.5 3 0 0 3 3 3 2 Sodium:neurotransmitter symporter family adh_short PF00106.20 KFH41459.1 - 1.1e-15 57.9 0.6 1.7e-15 57.3 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH41459.1 - 7e-09 35.5 0.3 1.1e-08 34.8 0.2 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFH41459.1 - 0.00059 19.6 0.0 0.00098 18.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Pkinase PF00069.20 KFH41460.1 - 2.8e-20 72.5 0.0 1.5e-19 70.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH41460.1 - 5.8e-10 38.6 0.0 0.00026 20.1 0.0 3.1 4 0 0 4 4 4 2 Protein tyrosine kinase APH PF01636.18 KFH41460.1 - 0.0029 17.3 0.0 0.0069 16.1 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KFH41460.1 - 0.15 10.9 0.0 15 4.4 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Iso_dh PF00180.15 KFH41461.1 - 3e-97 325.6 0.0 3.8e-97 325.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Clat_adaptor_s PF01217.15 KFH41462.1 - 1.2e-42 145.0 0.0 2.7e-42 143.8 0.0 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain TPT PF03151.11 KFH41463.1 - 9.3e-28 96.7 13.3 9.3e-28 96.7 9.2 2.3 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KFH41463.1 - 4.4e-06 25.8 25.3 0.001 18.0 7.5 2.1 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.15 KFH41463.1 - 0.00086 19.3 31.1 0.0025 17.8 6.1 2.6 3 0 0 3 3 3 2 EamA-like transporter family UCR_Fe-S_N PF10399.4 KFH41463.1 - 0.098 11.8 0.0 0.23 10.6 0.0 1.6 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF914 PF06027.7 KFH41463.1 - 0.33 9.7 17.8 0.81 8.4 11.5 2.0 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) HATPase_c PF02518.21 KFH41464.1 - 2.7e-28 97.9 0.0 6e-28 96.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KFH41464.1 - 2.6e-20 72.4 0.1 6.5e-20 71.2 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KFH41464.1 - 1.5e-19 69.7 0.4 8.3e-19 67.3 0.3 2.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 KFH41464.1 - 3.1e-12 46.8 0.1 4.6e-11 43.0 0.0 3.0 1 1 0 1 1 1 1 AAA ATPase domain GAF_2 PF13185.1 KFH41464.1 - 4.4e-09 36.9 0.0 1e-08 35.7 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 KFH41464.1 - 1.1e-08 35.1 0.0 2.7e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.20 KFH41464.1 - 1e-06 28.0 0.0 2.2e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain TPR_11 PF13414.1 KFH41464.1 - 0.00017 21.2 1.5 0.13 11.9 0.0 3.4 3 0 0 3 3 3 2 TPR repeat Pkinase_Tyr PF07714.12 KFH41464.1 - 0.00036 19.7 0.0 0.0007 18.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase NACHT PF05729.7 KFH41464.1 - 0.0022 17.6 0.2 0.76 9.4 0.0 2.8 3 0 0 3 3 3 1 NACHT domain AAA_22 PF13401.1 KFH41464.1 - 0.0023 18.0 0.0 0.12 12.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain HATPase_c_3 PF13589.1 KFH41464.1 - 0.0028 17.3 0.0 0.0058 16.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_8 PF13181.1 KFH41464.1 - 0.0033 17.0 0.1 1.3 8.9 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat NB-ARC PF00931.17 KFH41464.1 - 0.0088 14.9 0.0 0.03 13.1 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain ArgK PF03308.11 KFH41464.1 - 0.011 14.5 0.0 0.02 13.6 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_35 PF14516.1 KFH41464.1 - 0.017 13.7 0.0 0.036 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain TPR_2 PF07719.12 KFH41464.1 - 0.4 10.7 4.1 2.2 8.4 0.1 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 KFH41464.1 - 1.3 9.0 10.0 5.2 7.0 0.2 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat zf-CSL PF05207.8 KFH41465.1 - 1.3e-25 88.6 1.0 1.6e-25 88.3 0.7 1.1 1 0 0 1 1 1 1 CSL zinc finger TF_Zn_Ribbon PF08271.7 KFH41465.1 - 0.061 12.6 0.3 0.12 11.7 0.2 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.5 KFH41465.1 - 0.21 11.5 1.8 0.4 10.6 1.2 1.5 1 1 0 1 1 1 0 Zinc ribbon domain Prok-RING_1 PF14446.1 KFH41465.1 - 1.4 8.7 3.6 3.7 7.3 2.5 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 MAP7 PF05672.6 KFH41466.1 - 0.15 11.4 16.6 0.3 10.4 11.5 1.4 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Frataxin_Cyay PF01491.11 KFH41467.1 - 4.5e-34 116.5 0.0 6.5e-34 116.0 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain Complex1_LYR PF05347.10 KFH41469.1 - 3.1e-07 30.0 0.5 3.1e-07 30.0 0.4 1.7 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KFH41469.1 - 0.0048 17.0 0.4 0.01 16.0 0.2 1.7 1 0 0 1 1 1 1 Complex1_LYR-like tRNA-synt_1 PF00133.17 KFH41470.1 - 7.9e-37 126.5 0.0 9.3e-29 99.8 0.0 3.5 2 2 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KFH41470.1 - 8.7e-16 57.5 0.2 8.8e-11 41.0 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KFH41470.1 - 2.7e-10 40.1 2.2 4.3e-10 39.5 1.0 1.8 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 KFH41470.1 - 5.8e-07 28.9 0.0 1.2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Sugar_tr PF00083.19 KFH41471.1 - 4.1e-100 335.5 18.5 4.8e-100 335.2 12.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH41471.1 - 3.6e-25 88.4 34.5 1.7e-20 73.0 6.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFH41471.1 - 2.2e-08 32.9 23.5 4e-05 22.2 2.4 3.0 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 KFH41471.1 - 0.00072 19.3 0.4 0.024 14.4 0.0 2.6 2 0 0 2 2 2 1 MFS_1 like family DUF791 PF05631.9 KFH41471.1 - 0.00099 17.8 1.7 0.00099 17.8 1.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF791) MFS_3 PF05977.8 KFH41471.1 - 0.14 10.2 7.0 0.24 9.4 0.3 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector DEAD PF00270.24 KFH41472.1 - 2.2e-43 147.7 0.1 4.1e-43 146.7 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFH41472.1 - 9.1e-23 79.9 0.1 1.5e-12 47.1 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 KFH41472.1 - 8.4e-06 25.7 0.0 2e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TPR_11 PF13414.1 KFH41473.1 - 0.0015 18.1 0.3 0.091 12.4 0.1 2.6 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.1 KFH41473.1 - 0.0041 17.0 0.5 0.13 12.2 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFH41473.1 - 0.042 14.0 0.0 0.36 11.1 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFH41473.1 - 0.1 13.3 1.6 0.28 11.9 0.3 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L27e PF01777.13 KFH41474.1 - 2.3e-37 127.0 3.4 2.9e-37 126.6 2.4 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 KFH41474.1 - 0.00026 20.5 0.8 0.00094 18.8 0.2 2.2 2 0 0 2 2 2 1 KOW motif DUF1922 PF09082.5 KFH41474.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1922) ECM11 PF15463.1 KFH41474.1 - 0.16 12.2 1.5 0.18 12.0 0.2 1.5 2 0 0 2 2 2 0 Extracellular mutant protein 11 NAD_binding_8 PF13450.1 KFH41475.1 - 8.4e-07 28.9 0.2 1.9e-06 27.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KFH41475.1 - 2.4e-06 26.8 0.0 3.7e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DUF1344 PF07076.6 KFH41475.1 - 0.028 13.9 0.2 0.068 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) Pyr_redox_2 PF07992.9 KFH41475.1 - 0.09 12.6 0.1 0.39 10.5 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFH41475.1 - 0.11 12.5 0.2 0.24 11.4 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFH41475.1 - 0.16 11.7 0.3 2 8.1 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Chs3p PF12271.3 KFH41476.1 - 8.7e-105 349.8 4.0 1e-104 349.6 2.8 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit NADH-u_ox-rdase PF10785.4 KFH41476.1 - 0.49 10.6 7.8 0.62 10.3 0.2 3.1 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit DUF1218 PF06749.7 KFH41476.1 - 1.3 9.5 6.7 0.57 10.6 0.5 2.9 2 1 2 4 4 4 0 Protein of unknown function (DUF1218) DUF973 PF06157.6 KFH41476.1 - 1.8 7.4 13.3 1.9 7.4 1.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF973) UPF0016 PF01169.14 KFH41476.1 - 2.2 8.4 9.7 0.13 12.4 1.7 2.5 3 0 0 3 3 3 0 Uncharacterized protein family UPF0016 Ssl1 PF04056.9 KFH41479.1 - 3.5e-75 251.8 0.0 4.5e-75 251.4 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 KFH41479.1 - 1.9e-15 56.5 8.7 1.9e-15 56.5 6.0 2.7 2 2 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 KFH41479.1 - 1.5e-10 41.4 0.0 2.2e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Glyoxalase PF00903.20 KFH41481.1 - 3.9e-24 85.0 0.2 3.6e-15 56.0 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KFH41481.1 - 2.7e-12 46.6 0.1 1.2e-05 25.3 0.1 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KFH41481.1 - 7.5e-12 45.8 0.0 1.7e-06 28.6 0.1 2.6 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 KFH41481.1 - 1.6e-06 28.1 0.0 0.22 11.3 0.0 3.2 3 0 0 3 3 3 3 Glyoxalase-like domain Glyoxalase_5 PF14696.1 KFH41481.1 - 0.00025 21.0 0.1 0.0029 17.5 0.0 2.3 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal ABC_membrane_2 PF06472.10 KFH41482.1 - 8.5e-111 369.5 0.6 1.3e-110 368.9 0.4 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KFH41482.1 - 1.9e-17 63.8 0.0 4.4e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KFH41482.1 - 0.00024 21.1 0.0 0.00058 19.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 KFH41482.1 - 0.015 15.6 0.2 0.037 14.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KFH41482.1 - 0.018 15.0 0.2 0.065 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 KFH41482.1 - 0.022 14.3 0.0 0.056 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 KFH41482.1 - 0.035 13.2 0.0 0.065 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SMC_N PF02463.14 KFH41482.1 - 0.06 12.5 0.1 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.16 KFH41482.1 - 0.064 12.4 0.1 0.28 10.3 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 KFH41482.1 - 0.11 12.1 0.0 0.3 10.7 0.0 1.7 2 0 0 2 2 2 0 NACHT domain DUF2665 PF11654.3 KFH41483.1 - 6.1e-06 25.7 0.0 7.7e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2665) CTNNBL PF08216.6 KFH41484.1 - 1.5e-35 121.0 0.1 5.4e-35 119.2 0.0 2.0 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear HEAT_2 PF13646.1 KFH41484.1 - 0.0064 16.7 8.0 0.17 12.1 0.1 3.9 3 1 1 4 4 4 2 HEAT repeats Arm PF00514.18 KFH41484.1 - 0.013 15.3 0.6 0.16 11.8 0.0 3.1 3 1 0 3 3 3 0 Armadillo/beta-catenin-like repeat DJ-1_PfpI PF01965.19 KFH41485.1 - 2e-12 46.7 0.1 8.8e-12 44.6 0.0 1.9 1 1 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 KFH41485.1 - 0.0044 16.3 0.0 0.028 13.6 0.0 2.0 2 0 0 2 2 2 1 Putative amidotransferase SNO PF01174.14 KFH41485.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 SNO glutamine amidotransferase family IDO PF01231.13 KFH41487.1 - 2.8e-168 559.7 0.0 3.2e-168 559.5 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase STE2 PF02116.10 KFH41488.1 - 2.5e-43 148.1 7.1 2.9e-43 147.9 4.9 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR PalH PF08733.5 KFH41488.1 - 0.044 12.6 7.9 0.06 12.1 5.5 1.2 1 0 0 1 1 1 0 PalH/RIM21 MIT PF04212.13 KFH41489.1 - 3.4e-09 36.4 2.6 6.6e-09 35.5 1.8 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Glyco_hydro_16 PF00722.16 KFH41490.1 - 1e-18 67.2 0.6 2.3e-18 66.1 0.4 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 KFH41490.1 - 5.2e-09 34.7 2.8 8.5e-05 20.8 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) V-ATPase_G PF03179.10 KFH41491.1 - 8.4e-19 67.8 13.9 1.1e-18 67.4 9.7 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF2870 PF11069.3 KFH41491.1 - 0.027 14.4 4.4 0.039 13.9 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) DUF2201_N PF13203.1 KFH41491.1 - 0.11 11.6 6.2 0.13 11.3 4.3 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain RFXA_RFXANK_bdg PF15289.1 KFH41491.1 - 0.12 12.6 4.9 0.15 12.2 3.4 1.2 1 0 0 1 1 1 0 Regulatory factor X-associated C-terminal binding domain Rotamase_2 PF13145.1 KFH41491.1 - 0.27 11.8 9.0 0.38 11.4 6.2 1.2 1 0 0 1 1 1 0 PPIC-type PPIASE domain Atg14 PF10186.4 KFH41491.1 - 0.37 9.6 6.8 0.47 9.3 4.7 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Seryl_tRNA_N PF02403.17 KFH41491.1 - 0.49 10.4 12.5 0.43 10.6 7.9 1.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain HlyD PF00529.15 KFH41491.1 - 0.7 9.1 9.7 0.84 8.8 6.8 1.1 1 0 0 1 1 1 0 HlyD family secretion protein ATP-synt_B PF00430.13 KFH41491.1 - 0.74 9.6 13.6 1 9.1 9.4 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) OmpH PF03938.9 KFH41491.1 - 0.74 9.7 11.1 0.87 9.5 7.7 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.1 KFH41491.1 - 0.77 8.6 6.9 0.92 8.3 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF106 PF01956.11 KFH41491.1 - 1.1 8.7 4.9 1.3 8.5 3.4 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 Ribosomal_L6e PF01159.14 KFH41491.1 - 1.5 9.0 6.4 2.1 8.6 4.4 1.3 1 0 0 1 1 1 0 Ribosomal protein L6e TPR_20 PF14561.1 KFH41491.1 - 2.3 8.3 6.0 3.4 7.8 4.2 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat HSP70 PF00012.15 KFH41491.1 - 2.5 5.8 9.3 3 5.6 6.4 1.0 1 0 0 1 1 1 0 Hsp70 protein DUF3987 PF13148.1 KFH41491.1 - 6.9 5.1 12.1 8.3 4.8 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF4337 PF14235.1 KFH41491.1 - 7.6 6.3 8.8 10 5.9 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) EI24 PF07264.6 KFH41493.1 - 0.97 8.8 7.1 1.7 8.0 4.9 1.3 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) TT_ORF1 PF02956.9 KFH41493.1 - 1.6 7.1 10.9 2.1 6.7 7.6 1.1 1 0 0 1 1 1 0 TT viral orf 1 zf-CCHC PF00098.18 KFH41494.1 - 7.3e-16 57.2 28.3 1.7e-05 24.5 0.6 5.0 5 0 0 5 5 5 4 Zinc knuckle zf-CCHC_4 PF14392.1 KFH41494.1 - 0.0041 16.7 19.8 0.045 13.4 0.7 3.8 4 0 0 4 4 4 2 Zinc knuckle Viral_NABP PF05515.6 KFH41494.1 - 0.26 11.5 0.2 0.26 11.5 0.1 2.7 1 1 2 3 3 3 0 Viral nucleic acid binding ZZ PF00569.12 KFH41494.1 - 0.52 9.8 0.1 0.52 9.8 0.1 3.7 3 1 0 3 3 3 0 Zinc finger, ZZ type zf-CCHC_3 PF13917.1 KFH41494.1 - 0.84 9.4 21.8 0.49 10.1 0.2 4.1 1 1 2 3 3 3 0 Zinc knuckle DZR PF12773.2 KFH41494.1 - 4.7 7.1 19.4 2e+03 -1.3 12.2 3.1 2 1 0 2 2 2 0 Double zinc ribbon DnaJ_CXXCXGXG PF00684.14 KFH41494.1 - 5.1 7.2 17.0 3.1 7.8 6.8 2.4 1 1 1 2 2 2 0 DnaJ central domain zf-CCHC_6 PF15288.1 KFH41494.1 - 5.8 6.6 17.2 7 6.4 0.8 4.1 3 1 1 4 4 4 0 Zinc knuckle WD40 PF00400.27 KFH41495.1 - 2.2e-55 182.6 3.6 3e-07 30.0 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KFH41495.1 - 0.004 15.9 4.3 1.4 7.5 0.1 3.8 1 1 3 4 4 4 3 Nup133 N terminal like SGL PF08450.7 KFH41495.1 - 0.01 15.2 0.0 0.056 12.8 0.0 2.0 1 1 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region RRN3 PF05327.6 KFH41496.1 - 0.099 10.7 3.0 0.078 11.0 0.1 1.9 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 CorA PF01544.13 KFH41496.1 - 0.52 9.3 10.3 0.61 9.0 0.3 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Kinetocho_Slk19 PF12709.2 KFH41496.1 - 0.87 9.6 6.3 0.56 10.3 0.3 3.1 2 1 1 4 4 4 0 Central kinetochore-associated End3 PF12761.2 KFH41496.1 - 3.2 7.3 9.9 0.13 11.9 3.0 1.5 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 CENP-Q PF13094.1 KFH41496.1 - 5.4 7.0 15.4 0.13 12.2 0.6 3.5 1 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit MCM PF00493.18 KFH41497.1 - 2.1e-139 463.9 0.1 3.3e-139 463.2 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 KFH41497.1 - 1.4e-30 106.3 32.0 1.4e-30 106.3 22.2 2.6 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 KFH41497.1 - 3.1e-19 69.6 0.0 7.5e-19 68.4 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KFH41497.1 - 1.1e-07 31.2 0.0 5.8e-06 25.6 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KFH41497.1 - 6.9e-06 25.8 0.0 1.5e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 KFH41497.1 - 0.0027 17.1 0.2 0.019 14.4 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 KFH41497.1 - 0.0035 16.9 0.1 0.019 14.5 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) zf-TFIIB PF13453.1 KFH41497.1 - 0.045 12.9 1.4 0.1 11.8 1.0 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger Glyco_hydro_43 PF04616.9 KFH41499.1 - 4.9e-15 55.3 3.2 7.4e-15 54.7 2.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 RNA_pol_Rpb2_6 PF00562.23 KFH41500.1 - 7.9e-127 423.1 0.5 2.6e-126 421.4 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KFH41500.1 - 5.2e-53 179.0 0.0 8.5e-53 178.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KFH41500.1 - 2.2e-46 157.6 0.0 4.8e-46 156.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 KFH41500.1 - 2.1e-30 104.8 0.0 4.8e-30 103.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 KFH41500.1 - 6.3e-23 80.4 1.0 1.5e-22 79.2 0.7 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 KFH41500.1 - 1.1e-22 79.5 0.0 2.3e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 KFH41500.1 - 7e-18 64.2 0.2 1.9e-17 62.7 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 UEV PF05743.8 KFH41501.1 - 1.5e-39 134.3 0.1 3.2e-39 133.3 0.1 1.5 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 KFH41501.1 - 3.7e-22 77.6 0.0 7.2e-22 76.7 0.0 1.5 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.21 KFH41501.1 - 0.079 12.3 1.0 0.12 11.8 0.1 1.7 2 0 0 2 2 2 0 Ubiquitin-conjugating enzyme NTR2 PF15458.1 KFH41501.1 - 1.1 8.4 2.9 1.6 7.9 1.5 1.5 1 1 0 1 1 1 0 Nineteen complex-related protein 2 TFIIA PF03153.8 KFH41501.1 - 5.5 6.7 14.9 7.7 6.2 10.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GTP_EFTU PF00009.22 KFH41502.1 - 2.8e-49 167.1 0.0 4.7e-49 166.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 KFH41502.1 - 1.1e-38 131.4 5.4 1.8e-38 130.7 3.7 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 KFH41502.1 - 3e-18 65.4 0.0 5.7e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KFH41502.1 - 3.9e-05 23.6 0.2 8e-05 22.6 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KFH41502.1 - 3.9e-05 23.5 0.0 0.00012 22.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.1 KFH41502.1 - 0.00015 21.5 0.1 0.0008 19.2 0.0 2.3 2 1 0 2 2 2 1 Elongation Factor G, domain II Ras PF00071.17 KFH41502.1 - 0.0031 16.9 0.0 0.0088 15.4 0.0 1.7 2 0 0 2 2 2 1 Ras family His_Phos_1 PF00300.17 KFH41503.1 - 1.6e-19 70.5 0.0 2.1e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 KFH41503.1 - 0.015 14.6 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Protoglobin PF11563.3 KFH41504.1 - 4.9e-55 185.5 0.0 5.6e-55 185.3 0.0 1.0 1 0 0 1 1 1 1 Protoglobin TRAPP PF04051.11 KFH41505.1 - 5.9e-36 123.2 0.0 6.8e-36 123.0 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF4250 PF14056.1 KFH41505.1 - 0.056 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) DUF4386 PF14329.1 KFH41506.1 - 0.027 13.9 0.2 0.027 13.9 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4386) DUF1240 PF06836.7 KFH41506.1 - 0.028 14.6 0.1 0.079 13.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1240) zf-UBR PF02207.15 KFH41507.1 - 1.4e-15 56.7 4.3 1.4e-15 56.7 3.0 3.2 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) Glyco_hydro_31 PF01055.21 KFH41508.1 - 2.4e-171 570.4 0.4 3.2e-171 570.0 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KFH41508.1 - 2.7e-11 43.1 0.3 1.1e-10 41.2 0.2 2.2 1 0 0 1 1 1 1 Galactose mutarotase-like Toxin_20 PF08089.6 KFH41508.1 - 2.6 7.9 5.1 3.9 7.4 0.1 3.0 3 0 0 3 3 3 0 Huwentoxin-II family ParA PF10609.4 KFH41509.1 - 5.8e-37 125.4 0.0 1.1e-36 124.5 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KFH41509.1 - 8.6e-15 54.6 0.0 1.6e-14 53.7 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 KFH41509.1 - 5.2e-06 25.7 0.1 6.9e-05 22.0 0.0 2.0 2 0 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.10 KFH41509.1 - 4.3e-05 22.7 0.5 8.1e-05 21.8 0.3 1.4 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.1 KFH41509.1 - 7.2e-05 22.7 0.1 0.00019 21.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain YhjQ PF06564.7 KFH41509.1 - 0.0014 18.0 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 YhjQ protein ArgK PF03308.11 KFH41509.1 - 0.0016 17.2 0.3 0.0028 16.4 0.2 1.3 1 0 0 1 1 1 1 ArgK protein AAA_25 PF13481.1 KFH41509.1 - 0.0031 16.9 0.1 0.0054 16.1 0.1 1.3 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 KFH41509.1 - 0.04 13.0 0.3 0.085 12.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 APS_kinase PF01583.15 KFH41509.1 - 0.12 12.0 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase p450 PF00067.17 KFH41510.1 - 2.9e-39 134.8 0.0 5.3e-38 130.7 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 APH PF01636.18 KFH41511.1 - 2.5e-08 33.9 0.1 3.5e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFH41511.1 - 0.025 14.1 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase YhhN PF07947.9 KFH41512.1 - 4.4e-34 117.4 13.5 5.2e-34 117.2 9.3 1.1 1 0 0 1 1 1 1 YhhN-like protein YbjM PF11045.3 KFH41512.1 - 0.0052 16.5 1.0 0.0082 15.9 0.7 1.4 1 0 0 1 1 1 1 Putative inner membrane protein of Enterobacteriaceae adh_short PF00106.20 KFH41513.1 - 4.2e-07 30.0 0.0 7.8e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Eno-Rase_NADH_b PF12242.3 KFH41513.1 - 0.057 13.2 1.1 0.12 12.2 0.8 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ApbA PF02558.11 KFH41513.1 - 0.1 12.0 0.0 14 5.1 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA MIP PF00230.15 KFH41514.1 - 4.7e-11 42.5 1.0 5e-11 42.4 0.7 1.0 1 0 0 1 1 1 1 Major intrinsic protein WW PF00397.21 KFH41515.1 - 2.5e-06 27.2 6.7 4.3e-06 26.4 4.6 1.4 1 0 0 1 1 1 1 WW domain SAM_decarbox PF01536.11 KFH41516.1 - 6e-85 284.8 0.0 2e-83 279.8 0.0 2.8 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase Lipase_GDSL_2 PF13472.1 KFH41517.1 - 1.1e-12 48.3 0.1 1.5e-12 48.0 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFH41517.1 - 1.3e-07 31.6 0.0 6.8e-07 29.3 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_35 PF01301.14 KFH41518.1 - 4e-59 200.5 0.1 4.5e-59 200.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 KFH41518.1 - 7e-08 31.9 0.5 1.8e-06 27.3 0.3 2.0 1 1 0 1 1 1 1 Beta-galactosidase Glyco_hydro_14 PF01373.12 KFH41518.1 - 0.024 13.4 0.1 0.034 12.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 14 Glyco_hydro_35 PF01301.14 KFH41519.1 - 3.5e-15 56.1 1.1 4.7e-15 55.7 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 KFH41519.1 - 5.6e-06 26.5 0.0 1.6e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Virul_fac_BrkB PF03631.10 KFH41522.1 - 0.0074 15.6 5.9 0.01 15.1 4.1 1.1 1 0 0 1 1 1 1 Virulence factor BrkB DUF161 PF02588.10 KFH41522.1 - 0.015 15.5 4.0 0.59 10.4 0.3 2.4 2 1 0 2 2 2 0 Uncharacterized BCR, YitT family COG1284 YfhO PF09586.5 KFH41522.1 - 0.064 11.2 6.3 0.052 11.5 2.1 1.8 1 1 1 2 2 2 0 Bacterial membrane protein YfhO DUF4131 PF13567.1 KFH41522.1 - 0.067 12.5 4.9 2.2 7.6 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4526 PF15029.1 KFH41522.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4526) DUF373 PF04123.8 KFH41522.1 - 0.11 11.5 3.2 0.15 11.1 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) MFS_1 PF07690.11 KFH41522.1 - 0.15 10.7 9.3 0.2 10.3 6.5 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily Polyoma_agno PF01736.11 KFH41522.1 - 0.19 11.3 0.5 8.3 6.1 0.0 2.7 3 0 0 3 3 3 0 Polyomavirus agnoprotein DUF805 PF05656.9 KFH41522.1 - 1.8 8.3 12.6 0.68 9.7 3.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF805) Claudin_2 PF13903.1 KFH41522.1 - 2.3 7.8 12.8 5.2 6.7 5.8 2.5 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction MFS_1 PF07690.11 KFH41525.1 - 5.6e-37 127.2 29.9 9.2e-35 119.9 11.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH41526.1 - 1.2e-70 238.4 22.2 1.4e-70 238.1 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH41526.1 - 4.3e-22 78.3 27.5 4e-17 61.9 16.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Aa_trans PF01490.13 KFH41527.1 - 2.8e-58 197.3 34.2 3.2e-58 197.1 23.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Agro_virD5 PF04730.7 KFH41527.1 - 0.21 9.6 0.2 0.26 9.2 0.1 1.0 1 0 0 1 1 1 0 Agrobacterium VirD5 protein TIP120 PF08623.5 KFH41528.1 - 6.4e-58 195.0 0.7 6.3e-56 188.5 0.0 4.2 4 1 1 5 5 5 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 KFH41528.1 - 1.8e-19 69.7 27.8 0.0035 17.5 0.1 11.0 7 4 6 13 13 12 8 HEAT repeats HEAT PF02985.17 KFH41528.1 - 3.2e-12 45.4 19.4 0.45 10.7 0.1 11.0 12 0 0 12 12 11 4 HEAT repeat Adaptin_N PF01602.15 KFH41528.1 - 9.3e-09 34.1 6.3 0.018 13.4 0.0 7.3 5 2 1 7 7 7 2 Adaptin N terminal region DUF2435 PF10363.4 KFH41528.1 - 9.6e-07 28.6 5.2 0.49 10.3 0.0 6.1 7 1 1 8 8 7 2 Protein of unknown function (DUF2435) HEAT_EZ PF13513.1 KFH41528.1 - 6.3e-05 23.3 36.1 0.22 12.0 0.1 11.9 9 5 7 16 16 14 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KFH41528.1 - 0.00027 21.2 0.6 8.7 6.8 0.0 6.4 8 1 0 8 8 7 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 KFH41528.1 - 0.00061 19.6 9.7 10 5.9 0.0 6.2 4 2 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.3 KFH41528.1 - 0.027 14.1 2.5 21 4.7 0.2 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF3361) Proteasom_PSMB PF10508.4 KFH41528.1 - 0.039 12.2 1.1 0.41 8.8 0.0 3.0 3 1 1 4 4 4 0 Proteasome non-ATPase 26S subunit MMS19_C PF12460.3 KFH41528.1 - 0.052 12.2 0.6 0.87 8.2 0.1 3.4 3 1 0 3 3 3 0 RNAPII transcription regulator C-terminal RasGEF_N_2 PF14663.1 KFH41528.1 - 0.058 13.3 0.1 4.4 7.2 0.0 3.8 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain VHS PF00790.14 KFH41528.1 - 0.061 12.9 0.2 2.3 7.8 0.0 3.1 2 0 0 2 2 2 0 VHS domain NOB1_Zn_bind PF08772.6 KFH41529.1 - 7e-31 105.8 1.5 1.2e-30 105.1 1.0 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 KFH41529.1 - 0.00018 21.3 11.8 0.00018 21.3 8.2 3.1 3 1 0 3 3 3 1 Drug resistance and apoptosis regulator zf-NADH-PPase PF09297.6 KFH41529.1 - 0.69 9.4 6.2 0.12 11.9 0.5 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Nop10p PF04135.7 KFH41530.1 - 1.9e-19 69.1 0.0 3e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family YkuD_2 PF13645.1 KFH41530.1 - 0.094 11.9 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain Glyco_hydro_61 PF03443.9 KFH41531.1 - 3.8e-79 265.5 0.1 4.3e-79 265.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.4 KFH41531.1 - 0.031 14.3 0.0 0.072 13.1 0.0 1.6 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Big_3_4 PF13754.1 KFH41531.1 - 0.042 14.1 0.1 0.11 12.7 0.1 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) Ank_2 PF12796.2 KFH41532.1 - 1.7e-97 319.9 0.0 8.4e-13 48.4 0.0 16.6 9 5 4 15 15 15 15 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFH41532.1 - 6.2e-69 227.2 11.9 9.9e-08 32.3 0.0 22.2 13 7 10 23 23 23 17 Ankyrin repeats (many copies) Ank PF00023.25 KFH41532.1 - 3.9e-66 215.7 22.3 0.0012 18.5 0.0 27.5 26 4 0 26 26 26 16 Ankyrin repeat Ank_5 PF13857.1 KFH41532.1 - 1.3e-53 177.8 23.2 1.5e-05 25.0 0.2 20.7 20 4 4 24 24 24 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFH41532.1 - 2.1e-42 138.8 2.0 0.011 15.8 0.0 24.1 27 1 1 28 28 28 6 Ankyrin repeat Melibiase PF02065.13 KFH41533.1 - 4.7e-18 65.0 0.9 5.3e-17 61.5 0.0 2.2 1 1 1 2 2 2 2 Melibiase Tom37 PF10568.4 KFH41534.1 - 0.0069 16.6 0.0 0.033 14.4 0.0 2.1 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_3 PF14497.1 KFH41534.1 - 0.0097 16.3 0.1 0.019 15.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFH41534.1 - 0.051 13.4 1.6 0.13 12.1 1.1 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain HAD_2 PF13419.1 KFH41535.1 - 1.9e-26 93.3 2.2 9.8e-26 91.0 1.5 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFH41535.1 - 5.1e-09 36.8 0.0 8.2e-09 36.1 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFH41535.1 - 1.2e-05 24.9 0.0 2.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like TipAS PF07739.8 KFH41535.1 - 0.14 12.5 3.5 0.24 11.7 0.1 2.5 2 1 0 2 2 2 0 TipAS antibiotic-recognition domain Cons_hypoth95 PF03602.10 KFH41535.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Pkinase PF00069.20 KFH41536.1 - 6.3e-33 114.0 0.0 1.3e-32 113.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH41536.1 - 1.3e-11 44.0 0.0 6.1e-07 28.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KFH41536.1 - 0.047 13.4 0.0 0.25 11.0 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family IDO PF01231.13 KFH41537.1 - 9.9e-43 146.1 0.0 1.4e-42 145.6 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase CLTH PF10607.4 KFH41538.1 - 1.7e-30 105.6 0.7 2.1e-30 105.3 0.1 1.5 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 KFH41538.1 - 6.2e-24 84.4 0.1 1.1e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 KFH41538.1 - 6.5e-05 22.5 0.0 0.00014 21.4 0.0 1.6 1 0 0 1 1 1 1 LisH CDC14 PF08045.6 KFH41539.1 - 3.2e-93 311.5 0.0 3.6e-93 311.4 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component HAD_2 PF13419.1 KFH41540.1 - 1.4e-21 77.4 0.0 2.3e-21 76.7 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFH41540.1 - 2.4e-05 24.8 0.0 3e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFH41540.1 - 0.0027 17.3 0.0 0.0067 16.1 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 KFH41540.1 - 0.03 14.2 0.0 0.087 12.7 0.0 1.9 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Polyketide_cyc2 PF10604.4 KFH41540.1 - 0.18 11.9 2.3 0.33 11.1 0.1 2.3 3 0 0 3 3 3 0 Polyketide cyclase / dehydrase and lipid transport TPMT PF05724.6 KFH41541.1 - 6.4e-26 91.1 0.0 6.7e-25 87.8 0.0 1.9 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.2 KFH41541.1 - 8e-07 29.6 0.0 1.4e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH41541.1 - 4.2e-06 26.5 0.0 8.2e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH41541.1 - 0.00021 20.9 0.0 0.016 14.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFH41541.1 - 0.00025 21.0 0.1 0.0006 19.8 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 KFH41541.1 - 0.00048 19.3 0.0 0.00077 18.6 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_11 PF08241.7 KFH41541.1 - 0.0014 19.0 0.0 0.003 18.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFH41541.1 - 0.0023 18.2 0.0 0.0036 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH41541.1 - 0.017 15.5 0.0 0.067 13.6 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain LETM1 PF07766.8 KFH41542.1 - 6.6e-11 41.7 1.0 8.7e-09 34.8 0.1 2.1 2 0 0 2 2 2 2 LETM1-like protein DUF4452 PF14618.1 KFH41543.1 - 0.018 14.8 4.1 0.021 14.6 2.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) Atrophin-1 PF03154.10 KFH41543.1 - 0.28 9.3 4.5 0.28 9.2 3.1 1.0 1 0 0 1 1 1 0 Atrophin-1 family NMO PF03060.10 KFH41544.1 - 1.5e-37 129.4 3.2 2.3e-30 105.8 0.3 2.2 2 1 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 KFH41544.1 - 0.0057 15.5 5.1 0.0089 14.9 3.5 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 KFH41544.1 - 0.027 13.4 0.0 0.052 12.4 0.0 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase IMPDH PF00478.20 KFH41544.1 - 0.044 12.6 4.0 0.87 8.4 2.8 2.3 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KFH41544.1 - 0.047 12.6 0.3 0.073 11.9 0.2 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase OTU PF02338.14 KFH41545.1 - 2.8e-18 66.6 0.3 2.7e-17 63.4 0.0 2.6 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KFH41545.1 - 0.0045 16.3 0.0 1.1 8.5 0.0 2.4 2 0 0 2 2 2 2 Peptidase C65 Otubain DUF305 PF03713.8 KFH41545.1 - 0.77 9.5 8.8 1.3 8.7 0.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF305) Glutaredoxin2_C PF04399.8 KFH41546.1 - 0.97 9.0 5.7 1.2 8.7 1.2 2.4 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain YrhK PF14145.1 KFH41547.1 - 3.1e-07 29.9 17.2 0.00096 18.7 1.7 5.0 4 1 0 4 4 4 3 YrhK-like protein DUF2583 PF10762.4 KFH41547.1 - 0.89 9.7 5.4 0.28 11.3 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) EMP24_GP25L PF01105.19 KFH41548.1 - 2.5e-49 167.5 0.0 2.8e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Phage_HK97_TLTM PF06120.6 KFH41549.1 - 0.21 10.8 0.1 0.32 10.2 0.1 1.2 1 0 0 1 1 1 0 Tail length tape measure protein Ras PF00071.17 KFH41550.1 - 3.4e-51 172.8 0.0 7.1e-51 171.7 0.0 1.5 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KFH41550.1 - 1.1e-16 61.4 0.0 8.3e-15 55.3 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFH41550.1 - 0.0012 18.1 0.0 0.0045 16.2 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFH41550.1 - 0.01 15.7 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.13 KFH41550.1 - 0.014 14.6 0.1 0.11 11.7 0.0 2.1 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_25 PF13481.1 KFH41550.1 - 0.07 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain INO80_Ies4 PF08193.6 KFH41551.1 - 1.8e-64 217.7 24.2 2.1e-64 217.5 16.8 1.1 1 0 0 1 1 1 1 INO80 complex subunit Ies4 Mcp5_PH PF12814.2 KFH41552.1 - 1.9e-47 160.1 0.0 3.8e-47 159.2 0.0 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PSRP-3_Ycf65 PF04839.8 KFH41552.1 - 0.27 11.2 0.3 0.53 10.3 0.2 1.4 1 0 0 1 1 1 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) TPR_MLP1_2 PF07926.7 KFH41552.1 - 0.67 9.6 18.5 1.5 8.5 10.8 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein GAS PF13851.1 KFH41552.1 - 5.1 6.2 9.4 9.5 5.3 6.5 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding polyprenyl_synt PF00348.12 KFH41554.1 - 4.5e-57 192.8 0.0 5.3e-57 192.6 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase adh_short PF00106.20 KFH41555.1 - 9.8e-29 100.4 3.0 1.2e-28 100.0 2.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH41555.1 - 8.2e-23 81.4 0.0 1e-22 81.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH41555.1 - 6.5e-12 45.4 0.6 8.6e-12 45.0 0.4 1.2 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 KFH41555.1 - 0.015 15.3 0.0 0.034 14.2 0.1 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FTR PF01913.13 KFH41555.1 - 0.09 12.4 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase 3HCDH_N PF02737.13 KFH41555.1 - 0.16 11.6 0.2 0.22 11.1 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GAF_2 PF13185.1 KFH41556.1 - 1.4e-05 25.5 0.0 2.9e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 GAF domain GAF_3 PF13492.1 KFH41556.1 - 0.019 15.0 0.0 0.026 14.6 0.0 1.2 1 0 0 1 1 1 0 GAF domain GAF PF01590.21 KFH41556.1 - 0.027 14.6 0.0 0.06 13.4 0.0 1.5 1 1 0 1 1 1 0 GAF domain SCP2 PF02036.12 KFH41557.1 - 1e-24 86.7 0.2 1.3e-24 86.4 0.1 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 KFH41557.1 - 1.3e-05 25.1 0.1 1.8e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal C2 PF00168.25 KFH41558.1 - 7.5e-12 44.9 0.0 1.2e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain Aldo_ket_red PF00248.16 KFH41559.1 - 1.2e-70 237.5 0.0 1.4e-70 237.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AP_endonuc_2 PF01261.19 KFH41559.1 - 0.098 11.9 0.1 0.39 9.9 0.0 2.3 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel DUF4293 PF14126.1 KFH41560.1 - 1.7 8.5 5.9 0.28 11.1 0.7 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4293) DUF4117 PF13491.1 KFH41560.1 - 7.5 5.9 11.1 10 5.4 2.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4117) PX PF00787.19 KFH41561.1 - 7.2e-21 74.1 0.5 1.9e-20 72.7 0.3 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 KFH41561.1 - 7.4e-10 38.4 7.7 7.7e-05 22.0 0.6 2.2 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 KFH41561.1 - 1.9e-05 24.3 2.2 5.5e-05 22.7 1.5 1.7 1 1 0 1 1 1 1 BAR domain DUF3140 PF11338.3 KFH41561.1 - 0.012 15.6 0.2 0.047 13.8 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) Serglycin PF04360.7 KFH41561.1 - 0.025 14.3 0.0 5.8 6.6 0.0 2.3 2 0 0 2 2 2 0 Serglycin DUF3287 PF11690.3 KFH41561.1 - 0.097 12.7 1.0 15 5.6 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) Reo_sigmaC PF04582.7 KFH41561.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Atg14 PF10186.4 KFH41561.1 - 0.13 11.2 0.9 3.3 6.5 0.0 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 KFH41561.1 - 0.24 10.9 7.9 0.087 12.4 0.6 2.3 2 0 0 2 2 2 0 IncA protein Occludin_ELL PF07303.8 KFH41561.1 - 1.1 10.0 4.5 2.9 8.6 0.0 3.2 3 1 0 3 3 3 0 Occludin homology domain HSCB_C PF07743.8 KFH41561.1 - 2.3 8.7 8.9 3.8 8.0 1.2 2.8 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain Atg14 PF10186.4 KFH41562.1 - 7.6e-14 51.3 0.1 1.3e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 KFH41562.1 - 0.79 9.2 6.8 1.4 8.4 4.7 1.3 1 0 0 1 1 1 0 IncA protein Fib_alpha PF08702.5 KFH41562.1 - 2.7 8.1 5.3 4.3 7.4 3.7 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family HAUS-augmin3 PF14932.1 KFH41562.1 - 4.5 6.3 8.3 5 6.2 4.9 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF1798 PF08807.5 KFH41563.1 - 0.012 15.3 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) Phosphoprotein PF00922.12 KFH41563.1 - 0.058 12.6 2.3 0.076 12.2 1.6 1.2 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein DUF605 PF04652.11 KFH41563.1 - 0.91 8.8 5.7 1.1 8.6 4.0 1.1 1 0 0 1 1 1 0 Vta1 like NUDIX PF00293.23 KFH41565.1 - 2.9e-17 62.5 0.2 3.4e-17 62.3 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain Isochorismatase PF00857.15 KFH41566.1 - 5.3e-18 65.5 0.0 3e-16 59.8 0.0 2.1 1 1 0 1 1 1 1 Isochorismatase family DUF377 PF04041.8 KFH41567.1 - 6e-54 182.8 0.0 7.4e-54 182.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF377) Glyco_hydro_43 PF04616.9 KFH41567.1 - 6.5e-09 35.2 2.9 1e-06 28.1 0.0 3.7 3 1 0 4 4 4 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 KFH41567.1 - 4.6e-08 32.7 0.6 4.1e-07 29.6 0.0 2.3 2 1 0 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain Dabb PF07876.7 KFH41568.1 - 3.1e-17 62.7 0.1 4.1e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF4390 PF14334.1 KFH41568.1 - 0.022 13.9 0.0 0.036 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4390) ARL2_Bind_BART PF11527.3 KFH41568.1 - 0.13 12.0 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART Methyltransf_2 PF00891.13 KFH41570.1 - 5.3e-35 120.7 0.0 1.8e-34 118.9 0.0 1.8 1 1 0 1 1 1 1 O-methyltransferase MarR_2 PF12802.2 KFH41570.1 - 0.00024 20.6 0.0 0.0023 17.5 0.0 2.2 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.1 KFH41570.1 - 0.0034 17.6 0.0 0.016 15.5 0.0 2.0 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_IclR PF09339.5 KFH41570.1 - 0.0077 15.7 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain Rrf2 PF02082.15 KFH41570.1 - 0.012 15.7 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator Hairy_orange PF07527.8 KFH41570.1 - 0.058 13.1 0.1 0.22 11.3 0.0 2.0 2 0 0 2 2 2 0 Hairy Orange Serglycin PF04360.7 KFH41571.1 - 7.9e-05 22.4 4.9 0.00018 21.2 3.4 1.6 1 0 0 1 1 1 1 Serglycin Period_C PF12114.3 KFH41571.1 - 0.59 9.7 2.0 0.86 9.1 1.4 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region AF-4 PF05110.8 KFH41571.1 - 2.1 6.0 4.3 2.9 5.6 3.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Peptidase_S8 PF00082.17 KFH41572.1 - 5.1e-43 147.2 5.1 6.6e-43 146.8 3.5 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KFH41572.1 - 1.2e-14 54.6 0.0 2.4e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 WD40 PF00400.27 KFH41574.1 - 1.2e-14 53.4 6.6 5.7e-07 29.1 0.1 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF3312 PF11768.3 KFH41574.1 - 0.48 8.6 0.0 0.97 7.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Glyco_hydro_2 PF00703.16 KFH41575.1 - 2.3e-06 27.9 0.0 5.6e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 KFH41575.1 - 0.018 13.9 0.0 0.034 13.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain DUF4217 PF13959.1 KFH41575.1 - 0.17 11.4 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4217) Glyco_hydro_20 PF00728.17 KFH41576.1 - 1.6e-90 303.7 0.0 2e-90 303.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 KFH41576.1 - 4.9e-21 75.7 0.0 8.3e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 KFH41576.1 - 7e-08 33.0 0.1 5.1e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 20, domain 2 Peptidase_S8 PF00082.17 KFH41577.1 - 4.6e-41 140.8 0.6 3.5e-36 124.8 0.5 2.2 1 1 1 2 2 2 2 Subtilase family P_proprotein PF01483.15 KFH41577.1 - 4.1e-30 103.4 1.1 1e-29 102.1 0.7 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain RseC_MucC PF04246.7 KFH41577.1 - 0.29 10.6 0.0 0.56 9.7 0.0 1.4 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC p450 PF00067.17 KFH41578.1 - 1.3e-26 93.1 0.0 1.4e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 HMG-CoA_red PF00368.13 KFH41579.1 - 8.6e-156 518.2 6.2 1.2e-155 517.8 4.3 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 KFH41579.1 - 6e-45 152.6 0.1 1.3e-44 151.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 KFH41579.1 - 1.1e-14 54.1 7.2 1.7e-12 47.0 5.0 2.5 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 KFH41579.1 - 2.7e-09 35.5 4.1 4e-09 34.9 2.8 1.1 1 0 0 1 1 1 1 Patched family EVE PF01878.13 KFH41581.1 - 3.9e-46 156.6 0.0 7.2e-46 155.7 0.0 1.4 1 0 0 1 1 1 1 EVE domain DUF959 PF06121.9 KFH41581.1 - 0.49 9.9 7.9 0.66 9.5 5.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF959) Med3 PF11593.3 KFH41581.1 - 0.73 9.0 3.8 0.71 9.0 2.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Utp14 PF04615.8 KFH41582.1 - 6.2 4.8 27.2 9.4 4.2 18.8 1.3 1 0 0 1 1 1 0 Utp14 protein WD40 PF00400.27 KFH41583.1 - 2.3e-34 116.0 9.4 5.3e-12 45.1 0.1 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Ank_2 PF12796.2 KFH41584.1 - 5.9e-40 135.5 15.7 2.3e-06 27.8 0.0 13.1 8 5 3 11 11 11 9 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFH41584.1 - 1.2e-16 60.7 13.8 0.0012 19.2 0.0 10.9 10 1 1 11 11 11 5 Ankyrin repeats (many copies) Ank PF00023.25 KFH41584.1 - 1.5e-16 59.2 31.0 0.011 15.4 0.0 16.7 17 2 0 17 17 17 3 Ankyrin repeat Ank_3 PF13606.1 KFH41584.1 - 2.6e-13 48.7 14.9 5.7 7.4 0.0 14.7 17 0 0 17 17 17 3 Ankyrin repeat Ank_5 PF13857.1 KFH41584.1 - 2e-10 40.5 22.7 0.28 11.5 0.0 10.5 8 2 1 9 9 9 4 Ankyrin repeats (many copies) SRR1 PF07985.7 KFH41585.1 - 1.8e-05 24.5 0.0 4.9e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 SRR1 PFU PF09070.6 KFH41586.1 - 1.3e-44 150.8 0.3 2.4e-44 150.0 0.2 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.6 KFH41586.1 - 5.2e-43 146.7 0.0 8.5e-43 146.0 0.0 1.4 1 0 0 1 1 1 1 PUL domain WD40 PF00400.27 KFH41586.1 - 2.5e-37 125.4 12.4 2.4e-08 33.5 0.2 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat Glyco_hydro_17 PF00332.13 KFH41588.1 - 1.5e-08 34.0 1.9 4.1e-06 26.0 0.6 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 ETRAMP PF09716.5 KFH41588.1 - 0.033 14.1 0.1 0.033 14.1 0.0 3.1 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) WD40 PF00400.27 KFH41589.1 - 4.5e-20 70.7 4.0 0.0041 16.9 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat VWA_3 PF13768.1 KFH41591.1 - 1.8e-28 99.1 0.0 3.6e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 KFH41591.1 - 2.5e-20 72.3 0.0 6.1e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 KFH41591.1 - 1.9e-10 41.1 0.1 8.4e-10 39.0 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT_2 PF13757.1 KFH41591.1 - 3.1e-10 39.3 0.1 6.7e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 KFH41591.1 - 6.5e-07 29.2 0.1 2.1e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain Mito_fiss_reg PF05308.6 KFH41591.1 - 1.3 8.3 6.1 2.4 7.4 4.2 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator adh_short PF00106.20 KFH41592.1 - 2.3e-22 79.6 1.4 2.8e-22 79.3 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH41592.1 - 9.7e-09 35.3 0.0 1.2e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH41592.1 - 4.9e-08 32.8 0.8 8.1e-08 32.1 0.5 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFH41592.1 - 9e-08 32.3 0.3 1.8e-07 31.3 0.2 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFH41592.1 - 0.00011 21.7 0.2 0.001 18.5 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 KFH41592.1 - 0.0052 17.1 0.1 0.015 15.7 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 KFH41592.1 - 0.0087 15.0 0.2 0.0098 14.9 0.1 1.3 1 1 0 1 1 1 1 Saccharopine dehydrogenase Eno-Rase_NADH_b PF12242.3 KFH41592.1 - 0.023 14.4 0.1 0.054 13.2 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ApbA PF02558.11 KFH41592.1 - 0.044 13.2 0.0 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 KFH41592.1 - 0.045 13.8 0.3 0.11 12.6 0.1 1.7 1 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF429 PF04250.8 KFH41592.1 - 0.086 12.0 0.0 2.2 7.5 0.0 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF429) COPI_C PF06957.6 KFH41593.1 - 0.091 11.2 5.4 0.12 10.9 3.8 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Mpp10 PF04006.7 KFH41593.1 - 0.2 9.9 15.4 0.25 9.6 10.7 1.1 1 0 0 1 1 1 0 Mpp10 protein Alpha_kinase PF02816.13 KFH41594.1 - 2.4e-47 161.0 0.0 3.5e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family VWA_2 PF13519.1 KFH41594.1 - 5.8e-06 26.5 0.0 9.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KFH41594.1 - 1.5e-05 24.7 0.0 2.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 KFH41594.1 - 0.00015 21.5 0.1 0.0035 17.0 0.0 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain AAA_12 PF13087.1 KFH41597.1 - 1e-32 113.1 0.0 1.7e-32 112.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KFH41597.1 - 3e-23 82.6 0.5 1.9e-22 80.0 0.4 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KFH41597.1 - 2e-09 37.3 1.1 1.2e-06 28.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 KFH41597.1 - 2.6e-08 33.5 0.2 1.8e-06 27.5 0.0 3.2 2 1 1 3 3 3 1 Part of AAA domain PhoH PF02562.11 KFH41597.1 - 0.0016 17.7 0.0 0.0031 16.7 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein DUF2075 PF09848.4 KFH41597.1 - 0.0036 16.3 0.2 0.12 11.2 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 KFH41597.1 - 0.0057 16.2 0.5 1.1 8.7 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 KFH41597.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 KFH41597.1 - 0.013 14.8 2.0 0.48 9.6 1.0 2.9 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 KFH41597.1 - 0.021 14.9 0.0 0.35 11.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain LBR_tudor PF09465.5 KFH41597.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Zn_clus PF00172.13 KFH41598.1 - 8.1e-07 28.8 2.9 1.5e-06 27.9 2.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFH41598.1 - 7.1e-05 21.5 4.8 0.007 15.0 0.7 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Acetyltransf_1 PF00583.19 KFH41599.1 - 1.9e-07 31.0 0.1 3.3e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KFH41599.1 - 2.8e-06 27.4 0.0 3.6e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KFH41599.1 - 0.00052 20.1 0.0 0.00078 19.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 KFH41599.1 - 0.0028 17.6 0.0 0.0046 16.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFH41599.1 - 0.093 12.4 0.1 0.19 11.4 0.0 1.6 1 1 0 1 1 1 0 FR47-like protein HLH PF00010.21 KFH41601.1 - 5.5e-18 64.3 0.1 9e-18 63.7 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bZIP_1 PF00170.16 KFH41601.1 - 0.021 14.7 0.1 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 bZIP transcription factor Adeno_terminal PF02459.10 KFH41604.1 - 0.075 11.1 1.6 0.094 10.8 1.1 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein DUF1675 PF07897.6 KFH41604.1 - 0.23 11.3 6.1 0.26 11.0 4.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) ORC6 PF05460.8 KFH41604.1 - 1.4 7.9 10.1 1.5 7.7 7.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Pox_Ag35 PF03286.9 KFH41604.1 - 1.9 7.9 10.5 2.1 7.7 7.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein But2 PF09792.4 KFH41606.1 - 4.3e-07 29.7 0.0 1e-06 28.5 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain ACBP PF00887.14 KFH41607.1 - 1.8e-29 101.1 0.0 3.4e-29 100.3 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein DUF2269 PF10027.4 KFH41607.1 - 0.09 12.5 0.6 0.17 11.6 0.4 1.4 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) Atg14 PF10186.4 KFH41607.1 - 1.1 8.1 6.4 4.8 6.0 2.4 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 MRP-S33 PF08293.6 KFH41608.1 - 8.8e-28 96.1 0.1 1.1e-27 95.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Molybdopterin PF00384.17 KFH41609.1 - 7.7e-74 248.9 0.0 5.9e-72 242.7 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.1 KFH41609.1 - 7.2e-20 70.5 0.6 1.9e-19 69.2 0.2 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 KFH41609.1 - 4.9e-19 67.2 0.1 1.3e-18 65.8 0.1 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 KFH41609.1 - 7.1e-15 54.9 0.0 2e-14 53.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 KFH41609.1 - 6.4e-09 35.4 0.6 6.4e-09 35.4 0.4 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 KFH41609.1 - 0.0026 17.5 0.0 0.22 11.2 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.22 KFH41609.1 - 0.11 12.1 1.1 3.1 7.5 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain DUF3579 PF12112.3 KFH41609.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3579) SLAC1 PF03595.12 KFH41611.1 - 1.4e-54 185.0 41.6 3.6e-54 183.6 28.9 1.6 1 1 0 1 1 1 1 Voltage-dependent anion channel DUF3609 PF12259.3 KFH41611.1 - 0.12 11.0 0.0 0.21 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) Blt1 PF12754.2 KFH41612.1 - 5.7e-37 127.9 4.3 1.1e-30 107.3 0.3 2.2 1 1 1 2 2 2 2 Cell-cycle control medial ring component ubiquitin PF00240.18 KFH41612.1 - 0.0051 16.1 0.0 0.0087 15.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Cpn60_TCP1 PF00118.19 KFH41613.1 - 5.7e-111 371.5 11.8 1e-110 370.6 8.2 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Aldo_ket_red PF00248.16 KFH41614.1 - 4.6e-48 163.4 0.0 5.6e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ACPS PF01648.15 KFH41614.1 - 0.11 12.2 0.6 0.31 10.8 0.2 1.8 2 0 0 2 2 2 0 4'-phosphopantetheinyl transferase superfamily LpxK PF02606.9 KFH41614.1 - 0.11 11.3 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase DUF1751 PF08551.5 KFH41615.1 - 2.9e-05 24.3 0.1 5.2e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 KFH41615.1 - 0.0021 18.1 1.6 0.0053 16.7 1.1 1.7 1 1 0 1 1 1 1 Rhomboid family DER1 PF04511.10 KFH41615.1 - 0.008 15.6 2.2 0.011 15.2 1.5 1.2 1 0 0 1 1 1 1 Der1-like family Exo70 PF03081.10 KFH41617.1 - 0.053 12.2 4.2 0.11 11.2 2.5 1.7 1 1 0 1 1 1 0 Exo70 exocyst complex subunit CHASE3 PF05227.8 KFH41619.1 - 0.064 12.9 0.2 0.064 12.9 0.2 2.7 3 0 0 3 3 3 0 CHASE3 domain DUF2413 PF10310.4 KFH41619.1 - 3.4 6.3 7.0 6.6 5.4 4.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) APH PF01636.18 KFH41620.1 - 9.1e-05 22.2 0.0 0.00018 21.3 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFH41620.1 - 0.014 14.7 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 RIO1 family EcKinase PF02958.15 KFH41620.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase PAN_4 PF14295.1 KFH41621.1 - 0.0018 17.9 3.9 0.0041 16.7 2.7 1.7 1 0 0 1 1 1 1 PAN domain ETRAMP PF09716.5 KFH41621.1 - 0.22 11.4 0.1 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Ribonuclease_3 PF00636.21 KFH41623.1 - 2.9e-17 63.1 0.0 8.5e-17 61.6 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KFH41623.1 - 6.7e-10 39.0 0.0 1.4e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 KFH41623.1 - 0.0086 16.6 0.0 0.0086 16.6 0.0 1.9 2 0 0 2 2 2 1 Double-stranded RNA binding motif PUF PF00806.14 KFH41624.1 - 2.7e-40 133.5 0.1 2.5e-06 26.6 0.0 8.9 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat UPF0061 PF02696.9 KFH41625.1 - 1.1e-113 380.1 0.0 8.3e-113 377.2 0.0 1.8 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family DUF1127 PF06568.6 KFH41625.1 - 0.019 14.3 0.4 0.11 11.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1127) PP2C PF00481.16 KFH41626.1 - 4.3e-42 144.2 0.0 6.5e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KFH41626.1 - 5.1e-05 22.7 0.0 0.00011 21.6 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KFH41626.1 - 0.0011 18.6 0.1 0.047 13.3 0.0 2.5 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Cofilin_ADF PF00241.15 KFH41627.1 - 3.1e-07 30.3 1.1 3.8e-07 30.0 0.7 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein FYRC PF05965.9 KFH41627.1 - 0.14 12.0 0.1 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 F/Y rich C-terminus XRCC4 PF06632.7 KFH41629.1 - 8.4e-06 24.8 13.8 6e-05 22.0 9.6 2.0 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 YjgP_YjgQ PF03739.9 KFH41629.1 - 0.31 9.7 1.6 0.58 8.8 1.1 1.3 1 1 0 1 1 1 0 Predicted permease YjgP/YjgQ family Nol1_Nop2_Fmu PF01189.12 KFH41630.1 - 1.5e-95 319.8 0.0 2.5e-95 319.1 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 KFH41630.1 - 0.00012 22.0 0.0 0.00025 21.1 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.14 KFH41630.1 - 0.056 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.7 KFH41630.1 - 0.088 12.3 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) TAF4 PF05236.9 KFH41630.1 - 1.8 7.7 10.2 0.31 10.2 3.7 2.0 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family EF-hand_4 PF12763.2 KFH41631.1 - 1.3e-06 28.1 0.0 2.6e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_8 PF13833.1 KFH41631.1 - 0.021 14.4 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.27 KFH41631.1 - 0.025 13.8 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 EF hand Zip PF02535.17 KFH41631.1 - 4.4 6.2 13.4 4.1 6.3 2.4 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter MFS_1 PF07690.11 KFH41632.1 - 1.3e-20 73.4 73.9 1e-12 47.5 26.0 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PetM PF08041.6 KFH41632.1 - 2.7 7.5 6.0 1.2 8.6 0.4 3.2 3 0 0 3 3 3 0 PetM family of cytochrome b6f complex subunit 7 Myb_DNA-bind_6 PF13921.1 KFH41633.1 - 1.1e-13 51.1 0.3 7.9e-10 38.6 0.3 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KFH41633.1 - 7.5e-09 35.5 0.6 2.4e-05 24.2 0.0 2.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain DUF4085 PF13315.1 KFH41633.1 - 0.054 12.8 0.1 0.083 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) HTH_32 PF13565.1 KFH41633.1 - 0.12 13.1 0.0 0.37 11.6 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain SNF2_N PF00176.18 KFH41634.1 - 3.4e-72 242.7 0.0 5.6e-72 242.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFH41634.1 - 2.2e-13 49.8 0.0 1.1e-12 47.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KFH41634.1 - 0.0084 15.8 1.0 0.016 14.9 0.1 1.9 2 0 0 2 2 2 1 Part of AAA domain DEAD PF00270.24 KFH41634.1 - 0.011 15.2 0.0 0.11 11.9 0.0 2.5 2 1 0 2 2 2 0 DEAD/DEAH box helicase HR1 PF02185.11 KFH41634.1 - 0.76 9.5 12.1 0.034 13.8 4.2 2.0 2 0 0 2 2 2 0 Hr1 repeat AChE_tetra PF08674.5 KFH41634.1 - 3.1 7.3 5.3 9.2 5.8 3.6 1.7 1 0 0 1 1 1 0 Acetylcholinesterase tetramerisation domain MFS_1 PF07690.11 KFH41635.1 - 1.8e-32 112.4 36.0 1.8e-32 112.4 25.0 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily S1 PF00575.18 KFH41636.1 - 8.2e-89 291.7 31.3 1.1e-15 57.5 0.4 13.8 13 1 0 13 13 13 10 S1 RNA binding domain TPR_14 PF13428.1 KFH41636.1 - 4.2e-06 26.9 0.8 0.59 10.9 0.0 5.6 3 2 3 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFH41636.1 - 1.9e-05 24.9 0.0 1.3 9.4 0.0 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFH41636.1 - 0.002 18.7 0.0 1.1 9.9 0.0 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat Suf PF05843.9 KFH41636.1 - 0.0023 17.6 5.6 0.047 13.4 0.3 3.6 2 1 1 3 3 3 1 Suppressor of forked protein (Suf) NRDE-2 PF08424.5 KFH41636.1 - 0.0035 16.2 1.0 0.034 13.0 0.2 2.7 2 1 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_11 PF13414.1 KFH41636.1 - 0.047 13.3 0.0 0.33 10.6 0.0 2.5 2 0 0 2 2 2 0 TPR repeat PPR_2 PF13041.1 KFH41636.1 - 0.13 12.2 0.0 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 PPR repeat family TPR_2 PF07719.12 KFH41636.1 - 0.2 11.6 0.1 1.6 8.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.15 KFH41636.1 - 0.21 11.6 0.0 0.93 9.6 0.0 2.2 1 0 0 1 1 1 0 PPR repeat EXOSC1 PF10447.4 KFH41636.1 - 1 9.3 20.9 1.6 8.7 0.0 8.0 7 4 0 7 7 7 0 Exosome component EXOSC1/CSL4 Hemerythrin PF01814.18 KFH41637.1 - 2.1e-15 57.0 1.1 2.9e-15 56.6 0.7 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain BEX PF04538.7 KFH41637.1 - 0.15 12.2 1.3 13 6.0 0.0 2.9 3 0 0 3 3 3 0 Brain expressed X-linked like family Aldo_ket_red PF00248.16 KFH41639.1 - 2.8e-67 226.5 0.0 3.6e-67 226.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fe-S_biosyn PF01521.15 KFH41640.1 - 2.8e-11 43.3 0.0 1.2e-09 38.0 0.0 2.3 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Peptidase_M16_C PF05193.16 KFH41641.1 - 2.5e-47 160.9 0.0 4.6e-47 160.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KFH41641.1 - 1e-42 145.4 0.0 5.9e-40 136.4 0.0 2.2 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) DUF552 PF04472.7 KFH41641.1 - 0.16 11.9 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF552) Ribosomal_S11 PF00411.14 KFH41642.1 - 1.5e-34 118.5 1.4 1.8e-34 118.1 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 MAP65_ASE1 PF03999.7 KFH41643.1 - 1e-70 239.0 10.7 9.1e-70 235.9 7.4 2.0 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) zf-C4H2 PF10146.4 KFH41643.1 - 4.2e-05 23.6 1.5 4.2e-05 23.6 1.1 3.4 4 0 0 4 4 4 1 Zinc finger-containing protein LemA PF04011.7 KFH41643.1 - 0.027 13.5 0.0 0.081 12.0 0.0 1.8 1 0 0 1 1 1 0 LemA family RPW8 PF05659.6 KFH41643.1 - 0.062 12.8 0.2 0.062 12.8 0.1 2.5 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF948 PF06103.6 KFH41643.1 - 0.13 12.1 2.1 14 5.6 0.4 3.5 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF948) Sipho_Gp157 PF05565.6 KFH41643.1 - 0.27 10.8 4.8 0.17 11.4 0.2 2.5 2 0 0 2 2 2 0 Siphovirus Gp157 BLOC1_2 PF10046.4 KFH41643.1 - 0.67 10.1 5.5 7.2 6.8 0.0 4.0 4 1 1 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Arylsulfotran_2 PF14269.1 KFH41644.1 - 9.7e-53 179.2 2.0 1.4e-52 178.7 1.4 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KFH41644.1 - 1.4e-19 69.9 0.5 3.2e-19 68.8 0.3 1.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Ribosomal_L24e PF01246.15 KFH41645.1 - 1.7e-24 85.4 1.7 3.5e-24 84.4 1.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e Fungal_trans PF04082.13 KFH41646.1 - 1.3e-17 63.5 0.0 2.3e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH41646.1 - 1.6e-15 56.7 25.1 1.8e-08 34.1 6.0 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain FHA PF00498.21 KFH41647.1 - 3.3e-15 55.9 0.1 1e-14 54.3 0.0 1.9 2 0 0 2 2 2 1 FHA domain zf-RING_2 PF13639.1 KFH41647.1 - 6e-07 29.1 9.3 9.9e-07 28.4 6.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFH41647.1 - 9.4e-05 22.4 2.7 0.00018 21.5 1.9 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger PHD PF00628.24 KFH41647.1 - 0.0089 15.6 3.9 0.016 14.8 2.7 1.4 1 0 0 1 1 1 1 PHD-finger zf-C3HC4 PF00097.20 KFH41647.1 - 0.016 14.8 9.3 0.027 14.1 6.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFH41647.1 - 0.046 13.4 6.9 0.077 12.7 4.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain TFIIA PF03153.8 KFH41647.1 - 0.33 10.8 10.4 1.5 8.6 7.2 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-C3HC4_2 PF13923.1 KFH41647.1 - 0.45 10.5 10.7 0.76 9.8 7.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 KFH41647.1 - 1.2 9.2 5.3 2 8.4 3.7 1.4 1 0 0 1 1 1 0 RING-like domain ApbA_C PF08546.6 KFH41648.1 - 1.6e-24 86.2 0.0 3.1e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KFH41648.1 - 3.4e-17 62.2 0.0 1.2e-16 60.5 0.0 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA XylR_N PF06505.6 KFH41648.1 - 0.09 12.2 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Activator of aromatic catabolism GMC_oxred_C PF05199.8 KFH41649.1 - 2.6e-08 34.2 0.1 5.3e-08 33.2 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Abhydrolase_6 PF12697.2 KFH41649.1 - 9.4e-07 28.9 0.4 7.6e-06 25.9 0.1 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family GMC_oxred_N PF00732.14 KFH41649.1 - 1.3e-06 27.7 0.0 5.1e-05 22.5 0.0 2.5 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KFH41649.1 - 0.0027 16.6 0.3 0.0049 15.7 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain PEX11 PF05648.9 KFH41651.1 - 0.0074 15.5 2.2 2.6 7.2 0.0 2.7 2 1 0 3 3 3 2 Peroxisomal biogenesis factor 11 (PEX11) MBOAT_2 PF13813.1 KFH41652.1 - 8.9e-22 76.9 1.8 2e-21 75.8 1.3 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family eIF-3c_N PF05470.7 KFH41654.1 - 9.2e-171 568.9 22.0 2.8e-138 461.6 0.9 3.0 1 1 2 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 KFH41654.1 - 2.6e-11 43.7 0.0 7.6e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 PCI domain Streptin-Immun PF11083.3 KFH41654.1 - 0.0087 16.0 0.8 0.04 13.9 0.6 2.2 1 0 0 1 1 1 1 Lantibiotic streptin immunity protein Ribosomal_L30_N PF08079.7 KFH41655.1 - 5.5e-24 83.9 20.4 8.7e-24 83.3 14.2 1.3 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 KFH41655.1 - 4.7e-19 67.7 1.6 4.7e-19 67.7 1.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Endonuc_BglI PF14562.1 KFH41655.1 - 0.065 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease BglI Clathrin_lg_ch PF01086.12 KFH41655.1 - 0.067 13.1 4.3 0.09 12.6 3.0 1.1 1 0 0 1 1 1 0 Clathrin light chain Aldose_epim PF01263.15 KFH41656.1 - 3.2e-40 138.1 0.0 4.1e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Lamp PF01299.12 KFH41657.1 - 0.089 11.9 0.9 0.12 11.5 0.6 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) PepSY_2 PF13670.1 KFH41657.1 - 0.092 12.6 0.4 0.13 12.1 0.3 1.4 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain NMO PF03060.10 KFH41658.1 - 1.6e-70 237.8 3.3 1.9e-70 237.6 2.3 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KFH41658.1 - 2.5e-07 29.9 0.7 3.6e-06 26.1 0.5 2.3 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KFH41658.1 - 3.8e-06 25.9 2.8 3.8e-06 25.9 1.9 1.5 2 0 0 2 2 2 1 FMN-dependent dehydrogenase F-box-like PF12937.2 KFH41659.1 - 1.5e-05 24.5 0.1 3.6e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFH41659.1 - 5.7e-05 22.6 0.4 0.00018 21.0 0.3 1.8 1 0 0 1 1 1 1 F-box domain SNF2_N PF00176.18 KFH41661.1 - 3.2e-59 200.1 0.3 5.5e-59 199.3 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFH41661.1 - 2.5e-11 43.2 0.0 6.6e-11 41.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFH41661.1 - 3.7e-07 30.1 0.1 1e-06 28.6 0.1 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 KFH41661.1 - 3.7e-06 26.4 10.3 3.7e-06 26.4 7.1 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFH41661.1 - 0.0054 16.5 12.3 0.0054 16.5 8.6 2.1 2 0 0 2 2 1 1 Ring finger domain AAA_34 PF13872.1 KFH41661.1 - 0.0057 15.4 0.1 0.019 13.7 0.0 1.8 2 0 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 zf-C3HC4_3 PF13920.1 KFH41661.1 - 0.0099 15.5 10.4 0.0099 15.5 7.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFH41661.1 - 0.012 15.6 11.2 0.012 15.6 7.7 2.2 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) CCDC50_N PF15295.1 KFH41661.1 - 0.051 13.4 0.1 4.2 7.2 0.0 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 50 N-terminus zf-RING_6 PF14835.1 KFH41661.1 - 0.089 12.5 4.1 0.26 11.0 2.9 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.3 KFH41661.1 - 0.51 9.9 9.4 0.11 12.0 3.5 2.2 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Zn_clus PF00172.13 KFH41662.1 - 1.6e-17 63.1 24.8 1.3e-09 37.8 4.5 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFH41662.1 - 7.6e-15 54.4 0.1 1.2e-14 53.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain TRI12 PF06609.8 KFH41663.1 - 3.3e-34 118.0 2.5 3.9e-34 117.8 1.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KFH41663.1 - 2e-16 59.7 29.7 1.1e-15 57.1 19.7 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH41663.1 - 1.3e-07 30.5 10.7 1.3e-07 30.5 7.4 1.8 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.8 KFH41663.1 - 0.0021 16.2 0.2 0.0033 15.6 0.1 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector ABM PF03992.11 KFH41664.1 - 0.017 15.1 0.4 0.047 13.7 0.1 2.0 2 1 0 2 2 2 0 Antibiotic biosynthesis monooxygenase Ral PF11058.3 KFH41665.1 - 0.011 15.1 0.1 0.031 13.6 0.1 1.7 1 0 0 1 1 1 0 Antirestriction protein Ral bZIP_1 PF00170.16 KFH41665.1 - 0.31 11.0 4.9 0.57 10.1 3.1 1.6 1 1 0 1 1 1 0 bZIP transcription factor Glyco_hydro_3 PF00933.16 KFH41666.1 - 5.2e-88 294.8 0.0 7.4e-88 294.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KFH41666.1 - 8.4e-51 172.6 0.4 1.5e-49 168.5 0.3 2.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KFH41666.1 - 3.9e-22 77.9 0.1 7.5e-22 77.0 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain SurE PF01975.12 KFH41667.1 - 3.2e-27 95.1 0.0 4.5e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE COG2 PF06148.6 KFH41668.1 - 8.5e-26 90.3 0.2 1.2e-25 89.8 0.1 1.2 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 KFH41668.1 - 0.0002 21.1 0.2 0.0034 17.1 0.0 2.5 1 1 2 3 3 3 1 Vps51/Vps67 COG5 PF10392.4 KFH41668.1 - 0.0019 18.1 0.1 0.0041 17.0 0.1 1.6 1 0 0 1 1 1 1 Golgi transport complex subunit 5 DUF2450 PF10475.4 KFH41668.1 - 0.012 14.5 0.0 0.029 13.2 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) Spc7 PF08317.6 KFH41668.1 - 0.016 13.9 0.2 0.037 12.6 0.1 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.4 KFH41668.1 - 0.075 12.8 0.8 0.16 11.8 0.2 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.4 KFH41668.1 - 0.1 11.5 0.1 0.17 10.8 0.0 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Dor1 PF04124.7 KFH41668.1 - 0.12 10.8 0.3 0.18 10.2 0.2 1.2 1 0 0 1 1 1 0 Dor1-like family DEAD PF00270.24 KFH41670.1 - 1.7e-44 151.2 0.1 4e-44 150.0 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KFH41670.1 - 8.4e-22 76.4 0.2 1.8e-21 75.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KFH41670.1 - 2.8e-21 75.1 0.0 5.9e-21 74.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain WIYLD PF10440.4 KFH41670.1 - 0.012 15.5 0.0 0.24 11.3 0.0 2.6 3 0 0 3 3 3 0 Ubiquitin-binding WIYLD domain PARP PF00644.15 KFH41671.1 - 3.9e-63 212.5 0.2 2.6e-62 209.9 0.0 2.1 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 KFH41671.1 - 3.6e-42 143.1 0.1 5.4e-42 142.6 0.1 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 KFH41671.1 - 6.6e-22 77.2 0.0 2e-21 75.7 0.0 1.8 1 0 0 1 1 1 1 WGR domain BRCT PF00533.21 KFH41671.1 - 9.9e-13 48.0 0.0 2e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KFH41671.1 - 3.7e-07 29.8 0.1 8.7e-07 28.7 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain LEA_4 PF02987.11 KFH41672.1 - 0.0035 17.1 3.9 0.0059 16.4 2.7 1.3 1 0 0 1 1 1 1 Late embryogenesis abundant protein Ribosomal_L38e PF01781.13 KFH41673.1 - 5.1e-33 112.6 3.2 5.6e-33 112.4 2.2 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family NTF2 PF02136.15 KFH41674.1 - 0.026 14.8 0.9 0.32 11.3 0.6 2.2 1 1 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain NYD-SP28_assoc PF14775.1 KFH41674.1 - 0.045 13.4 0.2 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 Sperm tail C-terminal domain NAD_binding_10 PF13460.1 KFH41675.1 - 7.1e-16 58.7 0.0 9.5e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KFH41675.1 - 1.1e-14 54.2 0.0 1.4e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KFH41675.1 - 9.8e-06 25.1 0.0 0.0023 17.3 0.0 2.3 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KFH41675.1 - 0.052 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GHMP_kinases_N PF00288.21 KFH41676.1 - 6.4e-20 70.9 0.0 1.5e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KFH41676.1 - 7e-09 35.7 0.0 1.7e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal SBF PF01758.11 KFH41677.1 - 1e-48 165.2 7.8 1e-48 165.2 5.4 2.2 2 1 0 2 2 2 1 Sodium Bile acid symporter family LRR_6 PF13516.1 KFH41678.1 - 0.00033 20.3 5.1 0.014 15.3 0.1 5.6 6 1 0 6 6 6 1 Leucine Rich repeat LRR_7 PF13504.1 KFH41678.1 - 0.034 14.3 2.1 89 3.9 0.1 5.2 5 0 0 5 5 5 0 Leucine rich repeat Ribosomal_L1 PF00687.16 KFH41679.1 - 6.1e-28 97.6 0.0 1e-27 96.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Salt_tol_Pase PF09506.5 KFH41679.1 - 0.051 12.1 0.0 0.073 11.6 0.0 1.1 1 0 0 1 1 1 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) Ribosomal_L34 PF00468.12 KFH41680.1 - 1.8e-08 33.8 13.1 3e-08 33.1 9.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 Hap4_Hap_bind PF10297.4 KFH41681.1 - 4.8e-09 35.7 7.1 4.8e-09 35.7 4.9 2.5 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 KFH41681.1 - 6.5e-07 29.2 6.8 1.4e-06 28.1 4.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor SPX PF03105.14 KFH41681.1 - 0.0037 17.0 0.5 0.0049 16.6 0.3 1.2 1 0 0 1 1 1 1 SPX domain Cupin_6 PF12852.2 KFH41681.1 - 0.068 12.7 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 Cupin bZIP_2 PF07716.10 KFH41681.1 - 5.1 6.9 16.9 5.5 6.9 9.5 2.3 1 1 1 2 2 2 0 Basic region leucine zipper IncA PF04156.9 KFH41681.1 - 7.8 6.0 9.8 12 5.3 6.8 1.2 1 0 0 1 1 1 0 IncA protein PPTA PF01239.17 KFH41682.1 - 3.5e-44 146.3 15.2 3.8e-08 32.3 0.0 6.5 7 0 0 7 7 7 5 Protein prenyltransferase alpha subunit repeat TPR_7 PF13176.1 KFH41682.1 - 0.028 14.2 2.2 1.1 9.2 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFH41682.1 - 0.037 14.6 1.9 0.66 10.7 0.4 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 KFH41682.1 - 0.2 12.1 2.1 0.38 11.3 0.6 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat tRNA-synt_1g PF09334.6 KFH41683.1 - 1.1e-113 379.8 0.9 1.5e-113 379.4 0.6 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KFH41683.1 - 2.3e-24 85.3 4.1 2.7e-10 38.9 0.0 3.4 2 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) Acetyltransf_3 PF13302.1 KFH41683.1 - 1.1e-20 74.2 0.2 6.3e-20 71.7 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain tRNA-synt_1e PF01406.14 KFH41683.1 - 1e-07 31.4 0.1 0.003 16.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain FR47 PF08445.5 KFH41683.1 - 0.05 13.3 0.1 0.54 10.0 0.0 2.4 2 0 0 2 2 2 0 FR47-like protein Complex1_LYR_1 PF13232.1 KFH41683.1 - 0.076 13.2 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Complex1_LYR-like FAD_binding_4 PF01565.18 KFH41684.1 - 4.4e-21 74.8 0.0 7e-21 74.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain UnbV_ASPIC PF07593.7 KFH41684.1 - 0.086 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 ASPIC and UnbV Sedlin_N PF04628.8 KFH41685.1 - 3.1e-17 62.6 0.0 3.7e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region BA14K PF07886.6 KFH41685.1 - 0.16 11.7 0.2 0.42 10.3 0.3 1.6 2 0 0 2 2 2 0 BA14K-like protein Nucleoporin_N PF08801.6 KFH41686.1 - 1.9e-81 273.9 0.0 2.4e-81 273.6 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.9 KFH41686.1 - 1.4e-76 258.2 1.1 1.8e-76 257.9 0.8 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal PNGaseA PF12222.3 KFH41689.1 - 4.6e-75 253.1 0.1 2e-39 135.7 0.0 3.1 2 1 0 2 2 2 2 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF1279 PF06916.8 KFH41690.1 - 7.3e-26 90.3 0.1 1.3e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) BRI3BP PF14965.1 KFH41690.1 - 0.052 12.9 0.1 0.1 11.9 0.1 1.4 1 0 0 1 1 1 0 Negative regulator of p53/TP53 Glyco_tran_28_C PF04101.11 KFH41691.1 - 2.8e-19 69.4 0.0 2e-18 66.5 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 KFH41691.1 - 0.00097 18.4 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 1 Alba PF01918.16 KFH41692.1 - 0.00062 19.3 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Alba DUF3246 PF11596.3 KFH41692.1 - 0.059 12.6 1.8 0.087 12.0 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Aldedh PF00171.17 KFH41693.1 - 8.1e-72 242.0 0.0 9.7e-72 241.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Tctex-1 PF03645.8 KFH41694.1 - 3.8e-34 116.5 0.0 4.3e-34 116.4 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family NAD_binding_8 PF13450.1 KFH41695.1 - 0.097 12.7 0.1 0.13 12.2 0.1 1.2 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF4536 PF15055.1 KFH41695.1 - 0.17 11.9 3.3 0.34 11.0 2.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4536) Fringe PF02434.11 KFH41696.1 - 0.00018 20.8 0.3 0.0022 17.2 0.2 2.1 1 1 0 1 1 1 1 Fringe-like Acyl_transf_1 PF00698.16 KFH41697.1 - 4.2e-19 69.0 0.0 1.2e-13 51.1 0.0 2.1 1 1 0 2 2 2 2 Acyl transferase domain SPX PF03105.14 KFH41698.1 - 1.4e-14 54.5 4.5 9e-08 32.2 0.0 3.1 2 1 1 3 3 3 2 SPX domain CFEM PF05730.6 KFH41700.1 - 0.0051 16.6 10.5 0.0094 15.7 7.2 1.5 1 0 0 1 1 1 1 CFEM domain Pex19 PF04614.7 KFH41700.1 - 0.05 13.2 0.0 0.067 12.7 0.0 1.1 1 0 0 1 1 1 0 Pex19 protein family Phage_lysis PF03245.8 KFH41700.1 - 0.21 11.5 1.8 0.44 10.5 1.2 1.5 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein AFG1_ATPase PF03969.11 KFH41701.1 - 3.7e-52 177.3 0.0 1.2e-24 86.7 0.0 5.0 5 0 0 5 5 5 5 AFG1-like ATPase AAA_16 PF13191.1 KFH41701.1 - 0.00056 19.9 0.8 0.031 14.2 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KFH41701.1 - 0.00091 19.3 0.0 0.0042 17.2 0.0 2.1 2 1 0 2 2 2 1 AAA domain Bac_DnaA PF00308.13 KFH41701.1 - 0.0026 17.4 0.1 0.39 10.3 0.0 2.5 2 1 0 2 2 2 1 Bacterial dnaA protein KAP_NTPase PF07693.9 KFH41701.1 - 0.02 13.8 0.0 0.029 13.3 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_19 PF13245.1 KFH41701.1 - 0.021 14.5 0.0 1.6 8.5 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain AAA_5 PF07728.9 KFH41701.1 - 0.034 13.8 0.0 0.1 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 KFH41701.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.7 KFH41701.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain PIF1 PF05970.9 KFH41701.1 - 0.16 10.8 0.0 0.28 10.0 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase eIF-5_eIF-2B PF01873.12 KFH41702.1 - 1.9e-44 150.3 0.8 2.8e-44 149.7 0.5 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.1 KFH41702.1 - 0.05 13.8 0.2 0.15 12.3 0.1 1.8 1 0 0 1 1 1 0 Restriction alleviation protein Lar Ykof PF07615.6 KFH41702.1 - 0.075 13.1 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 YKOF-related Family Med19 PF10278.4 KFH41702.1 - 0.083 12.5 6.7 0.2 11.2 4.7 1.7 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 zf-HYPF PF07503.7 KFH41702.1 - 0.66 9.4 3.8 3 7.3 2.8 2.0 1 1 1 2 2 2 0 HypF finger Arc_trans_TRASH PF08394.5 KFH41702.1 - 1.1 9.4 7.7 1 9.5 0.2 2.5 1 1 1 2 2 2 0 Archaeal TRASH domain MARVEL PF01284.18 KFH41703.1 - 9.8e-20 70.8 14.0 1.1e-19 70.6 9.7 1.0 1 0 0 1 1 1 1 Membrane-associating domain Shisa PF13908.1 KFH41704.1 - 1.2 9.2 3.5 2.4 8.3 2.4 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator HMG14_17 PF01101.13 KFH41705.1 - 0.26 11.9 6.6 0.2 12.3 0.7 2.9 2 0 0 2 2 2 0 HMG14 and HMG17 DUF202 PF02656.10 KFH41706.1 - 3.2e-14 52.8 5.0 5.8e-14 52.0 2.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) 7TMR-DISM_7TM PF07695.6 KFH41706.1 - 0.014 15.0 1.7 0.037 13.6 0.4 1.8 2 0 0 2 2 2 0 7TM diverse intracellular signalling Bax1-I PF01027.15 KFH41706.1 - 0.027 14.0 2.6 0.035 13.7 1.8 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF1430 PF07242.6 KFH41706.1 - 0.19 11.8 1.5 3.8 7.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) Tic20 PF09685.5 KFH41706.1 - 0.24 11.4 6.0 1.5 8.8 4.2 1.9 1 1 0 1 1 1 0 Tic20-like protein Phageshock_PspG PF09583.5 KFH41706.1 - 0.33 11.0 0.3 0.33 11.0 0.2 2.4 3 0 0 3 3 3 0 Phage shock protein G (Phageshock_PspG) WD40 PF00400.27 KFH41707.1 - 5.9e-50 165.4 28.2 4e-10 39.1 0.1 11.1 11 0 0 11 11 11 9 WD domain, G-beta repeat PD40 PF07676.7 KFH41707.1 - 0.013 15.1 1.0 2 8.1 0.0 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat MRP-S28 PF10213.4 KFH41708.1 - 2.4e-45 153.6 0.4 4.2e-45 152.9 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein LTXXQ PF07813.7 KFH41708.1 - 0.16 12.4 8.2 0.28 11.6 0.0 3.4 3 0 0 3 3 3 0 LTXXQ motif family protein CWC25 PF12542.3 KFH41708.1 - 6.5 7.2 8.3 22 5.5 0.3 3.4 3 1 0 3 3 3 0 Pre-mRNA splicing factor SIS PF01380.17 KFH41709.1 - 1.2e-12 47.5 0.0 4.6e-12 45.6 0.0 1.8 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.1 KFH41709.1 - 0.00014 21.5 0.0 0.17 11.6 0.0 2.3 1 1 1 2 2 2 2 SIS domain ECR1_N PF14382.1 KFH41710.1 - 7.8e-10 37.8 0.1 1.7e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 KFH41710.1 - 0.00022 21.1 0.2 0.001 18.9 0.2 2.1 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 Fungal_trans PF04082.13 KFH41711.1 - 5.1e-07 28.8 0.0 1e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH41711.1 - 1.1e-05 25.2 14.2 2.1e-05 24.3 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Adap_comp_sub PF00928.16 KFH41712.1 - 3.6e-60 203.3 0.0 1.4e-59 201.3 0.0 1.8 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KFH41712.1 - 0.0005 19.8 0.0 0.00075 19.2 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain adh_short PF00106.20 KFH41714.1 - 9.3e-09 35.4 0.1 7.1e-08 32.5 0.0 2.2 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH41714.1 - 0.002 17.9 0.2 0.0031 17.3 0.2 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KFH41714.1 - 0.0051 16.2 0.1 0.032 13.6 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KFH41714.1 - 0.051 13.2 0.0 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 KR domain DAO PF01266.19 KFH41715.1 - 1e-16 60.8 0.0 5.9e-14 51.7 0.0 2.0 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFH41715.1 - 0.12 11.1 0.0 8.2 5.1 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 KFH41715.1 - 0.13 12.1 0.0 0.29 10.9 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.13 KFH41716.1 - 1.6e-15 56.6 0.0 4e-15 55.3 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH41716.1 - 2.9e-06 27.0 9.7 7.6e-06 25.7 6.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 KFH41716.1 - 0.045 13.6 2.0 0.078 12.9 0.3 2.1 2 0 0 2 2 2 0 Gal4-like dimerisation domain Sugar_tr PF00083.19 KFH41718.1 - 1.6e-61 208.2 23.4 1.8e-61 208.0 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH41718.1 - 4.7e-09 35.4 27.1 4.7e-09 35.4 18.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 KFH41718.1 - 0.0078 15.7 2.5 0.0078 15.7 1.8 2.5 4 0 0 4 4 4 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 KFH41719.1 - 1e-12 47.4 35.1 1e-12 47.4 24.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 KFH41719.1 - 5.4e-11 42.2 8.4 5.2e-10 39.0 3.4 2.9 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 DUF4051 PF13260.1 KFH41719.1 - 0.083 12.2 1.8 8.7 5.7 0.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) DUF1129 PF06570.6 KFH41719.1 - 2.6 7.2 6.9 0.39 10.0 0.2 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF1129) Ycf4 PF02392.11 KFH41719.1 - 6.1 6.1 9.8 0.21 10.9 2.4 1.7 2 0 0 2 2 2 0 Ycf4 Ecm33 PF12454.3 KFH41720.1 - 0.094 12.6 0.2 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Thiol-ester_cl PF10569.4 KFH41721.1 - 0.11 11.6 0.3 0.23 10.7 0.2 1.4 1 0 0 1 1 1 0 Alpha-macro-globulin thiol-ester bond-forming region TPR_12 PF13424.1 KFH41722.1 - 7.2e-23 80.3 0.1 3.3e-07 30.1 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat NB-ARC PF00931.17 KFH41722.1 - 6e-18 64.7 0.0 8.6e-18 64.1 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain TPR_16 PF13432.1 KFH41722.1 - 5.5e-12 46.0 3.5 0.0027 18.3 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFH41722.1 - 9.5e-12 44.3 0.9 4.2e-06 26.2 0.9 3.9 3 1 2 5 5 5 3 TPR repeat TPR_2 PF07719.12 KFH41722.1 - 2.3e-11 42.6 6.6 0.07 13.0 1.3 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 KFH41722.1 - 9.3e-11 41.2 9.7 0.0048 16.7 0.0 5.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFH41722.1 - 6.1e-10 38.8 14.3 0.44 11.3 0.0 6.1 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 KFH41722.1 - 6.1e-10 38.1 0.4 0.00047 19.7 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFH41722.1 - 5.5e-09 35.2 4.3 0.00049 19.5 0.5 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat AAA_16 PF13191.1 KFH41722.1 - 2.8e-07 30.6 1.1 0.0021 18.0 0.0 4.0 2 1 2 4 4 4 2 AAA ATPase domain TPR_7 PF13176.1 KFH41722.1 - 1.8e-06 27.2 1.8 2.3 8.2 0.1 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 KFH41722.1 - 1.2e-05 25.3 0.0 0.018 15.1 0.1 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 Arch_ATPase PF01637.13 KFH41722.1 - 3.5e-05 23.6 0.2 0.0019 17.9 0.0 3.2 1 1 2 3 3 3 1 Archaeal ATPase AAA_22 PF13401.1 KFH41722.1 - 0.00033 20.8 0.0 0.00088 19.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain TPR_19 PF14559.1 KFH41722.1 - 0.0015 18.8 3.9 0.75 10.1 0.0 4.2 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFH41722.1 - 0.056 13.9 6.9 44 4.8 0.0 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 KFH41722.1 - 0.069 13.6 0.7 0.069 13.6 0.5 4.8 5 0 0 5 5 3 0 Tetratricopeptide repeat PPR_3 PF13812.1 KFH41722.1 - 0.11 12.8 0.3 30 5.2 0.0 3.4 2 0 0 2 2 2 0 Pentatricopeptide repeat domain Copper-bind PF00127.15 KFH41723.1 - 0.04 14.1 0.0 0.044 14.0 0.0 1.1 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family Fungal_trans_2 PF11951.3 KFH41725.1 - 2e-27 95.7 1.2 5.1e-25 87.8 0.8 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH41725.1 - 6.8e-07 29.0 6.3 1.3e-06 28.1 4.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.6 KFH41726.1 - 7.8e-09 35.8 0.1 1.4e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1353 PF07087.6 KFH41726.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) ADH_zinc_N PF00107.21 KFH41728.1 - 3.8e-08 32.9 0.1 1.9e-07 30.6 0.0 2.2 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFH41728.1 - 0.00042 20.0 0.1 0.011 15.4 0.0 2.7 3 1 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 KFH41728.1 - 0.018 15.0 0.1 0.033 14.2 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding YqgF PF14639.1 KFH41729.1 - 0.03 13.8 0.0 0.04 13.4 0.0 1.1 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 Pkinase PF00069.20 KFH41730.1 - 5.1e-16 58.6 0.0 1.7e-12 47.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFH41730.1 - 0.00027 20.1 0.0 0.00084 18.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase zf-C2H2_jaz PF12171.3 KFH41731.1 - 1.4e-13 50.5 21.5 0.00013 22.0 0.3 5.5 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFH41731.1 - 2.1e-13 49.9 23.1 0.00026 21.0 2.4 5.9 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 KFH41731.1 - 4.4e-10 39.3 36.3 0.077 13.3 0.2 7.5 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 KFH41731.1 - 6.2e-10 39.1 20.8 0.096 12.7 2.4 6.1 2 2 4 6 6 6 3 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 KFH41731.1 - 6e-06 26.2 26.5 0.28 11.5 0.6 6.6 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 KFH41731.1 - 2.2e-05 24.1 23.5 0.28 11.1 0.1 6.9 6 1 1 7 7 7 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KFH41731.1 - 3.1e-05 23.9 32.3 0.73 10.3 0.9 7.7 8 0 0 8 8 8 3 C2H2-type zinc finger Elf1 PF05129.8 KFH41731.1 - 0.016 14.9 7.5 0.66 9.7 0.0 3.9 3 1 1 4 4 3 0 Transcription elongation factor Elf1 like zf-Di19 PF05605.7 KFH41731.1 - 0.029 14.4 0.1 0.029 14.4 0.1 4.5 4 2 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding DUF1178 PF06676.6 KFH41731.1 - 0.087 13.0 0.6 0.19 11.9 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) DUF3471 PF11954.3 KFH41731.1 - 0.093 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3471) AKAP95 PF04988.7 KFH41731.1 - 0.095 12.4 8.8 2.7 7.7 0.1 3.5 3 1 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) Yippee-Mis18 PF03226.9 KFH41731.1 - 0.24 11.4 8.5 0.86 9.6 0.5 3.4 3 1 1 4 4 4 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HypA PF01155.14 KFH41731.1 - 1.3 8.7 8.5 2.1 8.0 0.8 3.1 2 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family zf-C2HC_2 PF13913.1 KFH41731.1 - 2.6 7.7 13.0 7.2 6.3 0.0 4.9 5 0 0 5 5 5 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.5 KFH41731.1 - 4.6 7.2 20.5 16 5.5 0.2 6.0 4 1 1 5 5 5 0 Zinc ribbon domain zf-DBF PF07535.7 KFH41731.1 - 6.4 6.5 11.6 3.2 7.4 1.6 3.7 3 1 0 3 3 3 0 DBF zinc finger RasGEF PF00617.14 KFH41732.1 - 1.3e-55 188.0 0.1 2.4e-55 187.1 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KFH41732.1 - 2.7e-17 62.7 0.0 9.2e-17 61.0 0.0 1.9 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_9 PF14604.1 KFH41732.1 - 5.5e-06 25.8 0.0 1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFH41732.1 - 4.7e-05 22.6 0.0 0.0001 21.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFH41732.1 - 0.046 13.2 0.0 0.089 12.2 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain ADH_zinc_N_2 PF13602.1 KFH41733.1 - 6.3e-25 88.5 0.2 1.3e-24 87.4 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KFH41733.1 - 3.5e-19 68.6 0.7 1.4e-18 66.7 0.6 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase SDH_sah PF01972.11 KFH41733.1 - 0.0021 16.9 0.1 0.0054 15.5 0.0 1.7 3 0 0 3 3 3 1 Serine dehydrogenase proteinase DUF2855 PF11017.3 KFH41733.1 - 0.0075 15.4 0.0 0.01 14.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) ADH_N PF08240.7 KFH41733.1 - 0.014 15.1 0.0 0.078 12.7 0.0 2.2 2 1 1 3 3 3 0 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 KFH41733.1 - 0.048 13.2 0.1 0.066 12.7 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.16 KFH41733.1 - 0.068 12.7 0.2 0.15 11.6 0.1 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Microtub_assoc PF07989.6 KFH41734.1 - 7.8e-05 22.4 8.5 0.00011 22.0 4.9 1.9 2 0 0 2 2 2 1 Microtubule associated bZIP_1 PF00170.16 KFH41734.1 - 0.14 12.1 13.7 2.6 8.0 3.3 3.6 2 1 1 3 3 3 0 bZIP transcription factor PRKCSH PF07915.8 KFH41736.1 - 6.7e-19 68.4 0.4 2.5e-18 66.6 0.0 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Glycos_transf_1 PF00534.15 KFH41737.1 - 3.7e-20 72.0 0.0 4.1e-16 58.8 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KFH41737.1 - 2.4e-11 43.9 0.1 3.5e-09 36.9 0.0 3.2 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KFH41737.1 - 2.6e-05 24.3 0.0 8.7e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Utp12 PF04003.7 KFH41738.1 - 1.7e-23 82.6 0.2 3.4e-23 81.6 0.1 1.6 2 0 0 2 2 2 1 Dip2/Utp12 Family BUD22 PF09073.5 KFH41738.1 - 2.3 7.2 32.3 0.19 10.7 12.6 2.1 2 0 0 2 2 2 0 BUD22 SDA1 PF05285.7 KFH41738.1 - 3.3 6.9 36.4 0.74 9.0 3.2 2.1 2 0 0 2 2 2 0 SDA1 Nop14 PF04147.7 KFH41738.1 - 6.9 4.4 38.8 3.1 5.5 18.2 2.1 2 0 0 2 2 2 0 Nop14-like family AA_permease PF00324.16 KFH41741.1 - 5.1e-96 321.8 42.4 5.8e-96 321.7 29.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFH41741.1 - 2.6e-26 92.1 43.5 3.3e-26 91.8 30.1 1.1 1 0 0 1 1 1 1 Amino acid permease Ctr PF04145.10 KFH41741.1 - 0.38 10.7 10.2 0.28 11.2 1.0 3.3 3 0 0 3 3 3 0 Ctr copper transporter family HSP70 PF00012.15 KFH41742.1 - 7.9e-11 40.5 0.1 6.5e-10 37.5 0.0 1.9 2 0 0 2 2 2 1 Hsp70 protein DUF2439 PF10382.4 KFH41742.1 - 0.1 12.8 0.2 1.5 9.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2439) NUDIX PF00293.23 KFH41743.1 - 4.7e-06 26.2 0.0 7.2e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain His_Phos_2 PF00328.17 KFH41744.1 - 3.4e-32 112.1 0.0 4.3e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 KFH41744.1 - 0.0016 18.5 0.0 0.0025 17.8 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Sld5 PF05916.6 KFH41745.1 - 2e-08 34.5 0.0 2.6e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Lipase_GDSL PF00657.17 KFH41746.1 - 7.1e-09 35.8 0.0 9.6e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Sod_Fe_C PF02777.13 KFH41747.1 - 4.7e-36 122.8 0.3 7.9e-36 122.1 0.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KFH41747.1 - 1.1e-31 108.9 0.5 2e-31 108.0 0.4 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Ribonuclease PF00545.15 KFH41748.1 - 3.2e-17 62.3 0.4 5.9e-17 61.5 0.2 1.4 1 1 0 1 1 1 1 ribonuclease Bromodomain PF00439.20 KFH41749.1 - 4.8e-30 103.3 0.1 2e-16 59.6 0.0 2.5 2 0 0 2 2 2 2 Bromodomain DPBB_1 PF03330.13 KFH41751.1 - 2.4e-07 30.6 0.0 3.5e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KFH41751.1 - 0.0034 17.0 0.1 0.0047 16.5 0.1 1.2 1 0 0 1 1 1 1 Barwin family MFS_1 PF07690.11 KFH41752.1 - 1.8e-29 102.5 24.1 7.5e-28 97.2 18.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 KFH41753.1 - 6.1e-58 196.0 0.0 8.6e-58 195.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH41753.1 - 1.5e-30 106.1 0.0 6.3e-29 100.8 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KFH41753.1 - 0.02 13.7 0.0 0.028 13.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF1387 PF07139.6 KFH41753.1 - 0.066 12.8 0.9 0.55 9.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) Zip PF02535.17 KFH41755.1 - 3e-36 125.0 13.4 3.2e-30 105.2 5.3 2.5 2 1 0 2 2 2 2 ZIP Zinc transporter Methyltransf_23 PF13489.1 KFH41758.1 - 4.3e-16 59.0 0.0 6.5e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH41758.1 - 1.5e-07 31.7 0.0 3.3e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH41758.1 - 1.8e-07 30.8 0.0 3.2e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH41758.1 - 5.2e-07 30.0 0.0 8.8e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH41758.1 - 6.1e-07 30.0 0.0 1.5e-06 28.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KFH41758.1 - 0.0003 20.0 0.0 0.00046 19.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_4 PF02390.12 KFH41758.1 - 0.00076 18.5 0.0 0.0015 17.6 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 KFH41758.1 - 0.0026 17.1 0.0 0.0052 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KFH41758.1 - 0.0064 16.8 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFH41758.1 - 0.011 14.8 0.0 0.027 13.5 0.0 1.6 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 KFH41758.1 - 0.042 13.8 0.0 0.07 13.1 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 KFH41758.1 - 0.046 13.1 0.0 0.078 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase DUF938 PF06080.7 KFH41758.1 - 0.075 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_26 PF13659.1 KFH41758.1 - 0.1 12.6 0.1 0.29 11.1 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 KFH41758.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 KFH41758.1 - 0.14 11.1 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Mito_fiss_reg PF05308.6 KFH41758.1 - 0.71 9.2 3.5 1.2 8.4 2.4 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Brix PF04427.13 KFH41759.1 - 1e-37 129.6 0.0 1.4e-37 129.2 0.0 1.2 1 0 0 1 1 1 1 Brix domain Nop14 PF04147.7 KFH41759.1 - 0.76 7.6 20.6 0.99 7.2 14.3 1.1 1 0 0 1 1 1 0 Nop14-like family BORG_CEP PF14957.1 KFH41759.1 - 5.1 8.0 6.3 24 5.8 4.4 2.0 1 1 0 1 1 1 0 Cdc42 effector Abhydrolase_6 PF12697.2 KFH41761.1 - 1.5e-23 83.8 1.0 2.1e-23 83.4 0.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH41761.1 - 7.9e-06 25.6 0.0 1.1e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFH41761.1 - 0.00051 19.6 1.2 0.0015 18.1 0.4 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold NOC3p PF07540.6 KFH41762.1 - 2.3e-32 111.1 1.1 9.9e-31 105.8 0.1 3.2 3 0 0 3 3 3 1 Nucleolar complex-associated protein CBF PF03914.12 KFH41762.1 - 4.1e-28 97.9 1.8 8e-28 96.9 0.1 2.3 3 0 0 3 3 3 1 CBF/Mak21 family Pep3_Vps18 PF05131.9 KFH41763.1 - 1.5e-41 141.2 0.0 5.7e-41 139.3 0.0 2.0 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 KFH41763.1 - 7.6e-12 45.0 5.7 9.2e-08 31.7 0.0 3.5 3 0 0 3 3 3 2 Region in Clathrin and VPS DUF2175 PF09943.4 KFH41763.1 - 0.00053 19.9 0.6 0.0033 17.4 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2175) zf-RING_2 PF13639.1 KFH41763.1 - 0.00096 18.9 0.4 0.00096 18.9 0.3 1.9 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KFH41763.1 - 0.0024 17.5 0.5 0.0024 17.5 0.4 1.7 2 0 0 2 2 2 1 zinc-RING finger domain Nup96 PF12110.3 KFH41763.1 - 0.0075 15.4 0.1 0.85 8.6 0.0 2.2 2 0 0 2 2 2 2 Nuclear protein 96 zf-C3HC4_2 PF13923.1 KFH41763.1 - 0.092 12.7 0.6 0.26 11.3 0.4 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFH41763.1 - 0.23 11.1 0.7 0.85 9.3 0.5 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) 2OG-FeII_Oxy_3 PF13640.1 KFH41765.1 - 0.00026 21.4 0.1 0.00044 20.7 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KFH41765.1 - 0.0032 17.7 0.0 0.015 15.5 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KFH41765.1 - 0.042 13.4 0.5 0.085 12.5 0.3 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily HK97-gp10_like PF04883.7 KFH41766.1 - 0.028 15.3 0.1 0.079 13.9 0.0 1.7 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component Baculo_PEP_C PF04513.7 KFH41766.1 - 0.057 13.2 0.9 0.17 11.7 0.6 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2791 PF10923.3 KFH41766.1 - 0.11 11.1 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Cob_adeno_trans PF01923.13 KFH41766.1 - 0.12 12.1 0.0 0.34 10.6 0.0 1.6 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Prominin PF05478.6 KFH41766.1 - 0.14 9.6 0.1 0.17 9.3 0.0 1.0 1 0 0 1 1 1 0 Prominin SIN1 PF05422.7 KFH41767.1 - 4.1e-38 131.1 0.1 9.2e-18 64.0 0.0 3.2 3 0 0 3 3 3 3 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 KFH41767.1 - 0.00018 21.3 0.0 0.00037 20.3 0.0 1.5 1 0 0 1 1 1 1 GLUT4 regulating protein TUG GTP_cyclohydro2 PF00925.15 KFH41767.1 - 0.022 14.0 0.0 0.057 12.6 0.0 1.6 1 0 0 1 1 1 0 GTP cyclohydrolase II Exonuc_VIII PF06630.6 KFH41767.1 - 0.023 14.0 0.6 0.13 11.5 0.2 2.1 2 0 0 2 2 2 0 Enterobacterial exodeoxyribonuclease VIII TFIIF_alpha PF05793.7 KFH41767.1 - 6 5.1 19.0 0.0069 14.8 5.0 2.0 3 0 0 3 3 3 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PRCC PF10253.4 KFH41768.1 - 8.6e-39 134.1 0.8 8.6e-39 134.1 0.6 2.7 2 2 1 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting BRF1 PF07741.8 KFH41769.1 - 0.0028 17.8 4.0 0.0028 17.8 2.8 4.1 2 1 0 2 2 2 1 Brf1-like TBP-binding domain Epimerase PF01370.16 KFH41770.1 - 7.8e-58 195.6 0.0 9.7e-58 195.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KFH41770.1 - 4e-24 85.0 0.0 5.5e-23 81.2 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KFH41770.1 - 2e-22 79.3 0.0 2.7e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 KFH41770.1 - 3.1e-22 78.5 0.0 3.8e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KFH41770.1 - 5.6e-21 74.5 0.3 4e-20 71.7 0.2 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KFH41770.1 - 1.7e-09 37.9 0.0 2.8e-09 37.2 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KFH41770.1 - 0.0023 17.8 0.1 0.17 11.7 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase AMP-binding PF00501.23 KFH41771.1 - 9.5e-76 254.8 0.0 1.4e-75 254.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KFH41771.1 - 1.1e-64 217.7 0.0 1.8e-64 217.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KFH41771.1 - 1.3e-09 37.8 0.0 2.4e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KFH41771.1 - 5e-08 33.0 0.0 9.9e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KFH41771.1 - 8.6e-08 33.0 0.6 4e-06 27.6 0.0 3.3 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.1 KFH41771.1 - 0.00014 21.8 0.0 0.0067 16.4 0.0 2.4 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KFH41771.1 - 0.00034 19.4 0.0 0.00062 18.5 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KFH41771.1 - 0.018 14.9 0.2 0.056 13.3 0.1 1.9 1 1 0 1 1 1 0 short chain dehydrogenase HsbA PF12296.3 KFH41772.1 - 3.6e-26 91.4 2.3 3.6e-26 91.4 1.6 1.5 2 0 0 2 2 2 1 Hydrophobic surface binding protein A Aldedh PF00171.17 KFH41773.1 - 4.4e-161 536.3 0.0 4.9e-161 536.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KFH41773.1 - 0.16 11.1 0.0 0.74 9.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Ras PF00071.17 KFH41774.1 - 1.4e-22 79.8 0.0 1.7e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFH41774.1 - 1.4e-06 28.8 0.0 1.9e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein ATP-synt_C PF00137.16 KFH41775.1 - 3e-25 87.8 25.3 4.6e-16 58.4 7.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C TCR_zetazeta PF11628.3 KFH41775.1 - 0.3 10.5 5.0 6.7 6.2 0.3 2.6 3 0 0 3 3 3 0 T-cell surface glycoprotein CD3 zeta chain DUF3816 PF12822.2 KFH41775.1 - 1.6 8.5 14.7 0.43 10.4 7.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3816) TctB PF07331.6 KFH41775.1 - 7.4 6.2 16.9 1.7e+02 1.8 11.6 2.0 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Asp PF00026.18 KFH41776.1 - 8.9e-66 222.2 0.0 1.1e-65 221.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFH41776.1 - 9.3e-10 38.7 0.6 2.6e-09 37.2 0.1 2.1 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KFH41776.1 - 0.00059 19.4 0.0 0.0077 15.7 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KFH41776.1 - 0.022 15.2 2.7 1.3 9.6 0.1 3.7 3 1 0 3 3 3 0 Aspartyl protease Fungal_trans PF04082.13 KFH41777.1 - 5.9e-14 51.5 0.0 9.6e-14 50.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH41777.1 - 5.8e-10 38.9 10.6 5.8e-10 38.9 7.3 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3719 PF12516.3 KFH41778.1 - 0.039 13.5 0.0 0.41 10.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3719) DUF1749 PF08538.5 KFH41779.1 - 2.1e-83 279.7 0.0 2.5e-83 279.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 KFH41779.1 - 4.4e-17 62.7 0.0 5.6e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH41779.1 - 1.6e-08 34.4 0.0 2e-07 30.8 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 KFH41779.1 - 0.0039 16.8 0.0 0.0071 15.9 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_1 PF00561.15 KFH41779.1 - 0.029 13.9 0.0 0.061 12.8 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KFH41779.1 - 0.051 13.1 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Pkinase PF00069.20 KFH41780.1 - 1.1e-37 129.5 0.0 1.7e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH41780.1 - 4.9e-27 94.6 0.0 9.8e-27 93.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH41780.1 - 0.0017 17.3 0.0 0.0028 16.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFH41780.1 - 0.0065 15.5 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFH41780.1 - 0.0099 15.6 0.0 1.9 8.1 0.0 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family NUDIX PF00293.23 KFH41781.1 - 8e-16 57.9 0.0 1.6e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 KFH41781.1 - 3e-14 53.1 0.0 7.5e-14 51.8 0.0 1.7 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 KFH41781.1 - 5.5e-05 22.5 0.2 0.0001 21.7 0.1 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Sugar_tr PF00083.19 KFH41782.1 - 6.6e-47 160.1 1.4 7.5e-47 159.9 1.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Pkinase PF00069.20 KFH41783.1 - 4.9e-69 232.3 0.0 8.9e-69 231.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH41783.1 - 1.9e-49 168.0 0.0 3.3e-49 167.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 KFH41783.1 - 2.1e-29 101.5 0.0 4.6e-29 100.4 0.0 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 KFH41783.1 - 2.1e-17 62.7 0.3 2.5e-16 59.2 0.0 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFH41783.1 - 1.9e-15 56.7 0.1 3.5e-15 55.9 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 KFH41783.1 - 3.6e-13 49.8 0.0 6.8e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.1 KFH41783.1 - 9.6e-08 31.3 0.0 9.7e-05 21.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like SAM_PNT PF02198.11 KFH41783.1 - 0.03 14.0 0.0 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Kdo PF06293.9 KFH41783.1 - 0.076 12.0 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AIG2 PF06094.7 KFH41784.1 - 0.00013 22.4 0.0 0.00023 21.6 0.0 1.4 1 1 0 1 1 1 1 AIG2-like family AIG2_2 PF13772.1 KFH41784.1 - 0.00013 22.0 0.0 0.00025 21.1 0.0 1.6 1 0 0 1 1 1 1 AIG2-like family AAA_16 PF13191.1 KFH41785.1 - 0.0026 17.7 0.0 0.0031 17.5 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 KFH41785.1 - 0.062 12.1 0.0 0.072 11.9 0.0 1.0 1 0 0 1 1 1 0 NB-ARC domain CbiA PF01656.18 KFH41785.1 - 0.083 12.2 0.3 0.099 12.0 0.2 1.1 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.1 KFH41785.1 - 0.098 12.0 0.1 0.098 12.0 0.1 1.1 1 0 0 1 1 1 0 AAA domain Sulfotransfer_3 PF13469.1 KFH41787.1 - 0.013 16.4 0.6 0.059 14.3 0.1 2.2 1 1 0 1 1 1 0 Sulfotransferase family PQ-loop PF04193.9 KFH41788.1 - 1.5e-37 126.9 13.0 2e-19 68.8 1.2 2.6 2 0 0 2 2 2 2 PQ loop repeat Cytochrom_C_asm PF01578.15 KFH41788.1 - 0.56 9.7 6.8 5.8 6.4 0.5 2.3 2 0 0 2 2 2 0 Cytochrome C assembly protein LON PF02190.11 KFH41790.1 - 1.6e-27 96.5 0.0 3.2e-27 95.5 0.0 1.5 1 1 0 1 1 1 1 ATP-dependent protease La (LON) domain DUF2567 PF10821.3 KFH41790.1 - 0.12 11.8 0.1 0.19 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2567) DUF2414 PF10309.4 KFH41790.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2414) PIG-X PF08320.7 KFH41791.1 - 7e-61 205.1 0.0 9.8e-61 204.6 0.0 1.1 1 0 0 1 1 1 1 PIG-X / PBN1 CoaE PF01121.15 KFH41792.1 - 8.6e-42 142.5 0.0 3.5e-41 140.5 0.0 1.7 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.1 KFH41792.1 - 0.00024 20.9 0.0 0.0017 18.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFH41792.1 - 0.0059 17.4 1.4 0.026 15.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KFH41792.1 - 0.01 16.1 0.3 0.3 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain RTC_insert PF05189.8 KFH41792.1 - 0.052 13.5 0.1 0.095 12.7 0.1 1.4 1 0 0 1 1 1 0 RNA 3'-terminal phosphate cyclase (RTC), insert domain WD40 PF00400.27 KFH41794.1 - 1.3e-14 53.4 0.5 1.6e-05 24.5 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat HEAT_2 PF13646.1 KFH41795.1 - 9.6e-05 22.5 11.9 0.65 10.3 0.0 5.3 7 1 0 7 7 7 3 HEAT repeats Urb2 PF10441.4 KFH41795.1 - 0.029 13.9 0.2 0.13 11.8 0.1 2.1 1 0 0 1 1 1 0 Urb2/Npa2 family HEAT PF02985.17 KFH41795.1 - 0.038 14.0 3.8 32 4.9 0.0 5.9 6 0 0 6 6 6 0 HEAT repeat DUF2682 PF10909.3 KFH41795.1 - 0.62 10.3 3.0 4.8 7.5 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2682) ABC_membrane PF00664.18 KFH41796.1 - 5.8e-77 258.7 37.7 9.9e-41 139.9 7.0 3.0 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFH41796.1 - 6e-53 178.8 0.1 1.1e-30 106.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KFH41796.1 - 2.4e-10 40.0 3.6 0.0099 15.1 0.2 4.4 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KFH41796.1 - 2.5e-08 34.1 1.0 0.0038 17.2 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 KFH41796.1 - 9.2e-06 26.1 0.3 0.0048 17.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.1 KFH41796.1 - 1.6e-05 25.0 0.1 0.069 13.1 0.0 3.7 3 1 1 4 4 4 1 AAA domain AAA_29 PF13555.1 KFH41796.1 - 4.2e-05 22.9 0.2 0.41 10.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KFH41796.1 - 4.4e-05 23.4 0.0 0.4 10.6 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 KFH41796.1 - 0.00014 21.0 0.0 0.16 11.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF87 PF01935.12 KFH41796.1 - 0.00029 20.7 1.2 0.7 9.6 0.1 2.7 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_25 PF13481.1 KFH41796.1 - 0.00034 20.0 0.0 0.18 11.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KFH41796.1 - 0.00072 20.0 0.1 2 8.9 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein Arch_ATPase PF01637.13 KFH41796.1 - 0.0096 15.6 0.0 0.16 11.6 0.0 2.7 3 0 0 3 3 3 1 Archaeal ATPase AAA_22 PF13401.1 KFH41796.1 - 0.013 15.6 1.2 5.4 7.1 0.0 3.3 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KFH41796.1 - 0.028 13.8 0.0 2.7 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain AAA_17 PF13207.1 KFH41796.1 - 0.032 15.0 0.3 3.1 8.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KFH41796.1 - 0.046 12.8 0.1 3.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.13 KFH41796.1 - 0.059 12.8 0.4 3.5 7.0 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 KFH41796.1 - 0.065 13.0 4.0 1.2 8.9 0.0 2.9 3 0 0 3 3 3 0 Dynamin family ATP_bind_1 PF03029.12 KFH41796.1 - 0.082 12.4 3.0 8.6 5.8 0.0 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 KFH41796.1 - 0.17 11.3 0.3 12 5.2 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain cobW PF02492.14 KFH41796.1 - 0.18 11.2 0.9 0.61 9.5 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SLAIN PF15301.1 KFH41796.1 - 1.1 8.3 7.5 1.7 7.7 5.2 1.2 1 0 0 1 1 1 0 SLAIN motif-containing family Zn_clus PF00172.13 KFH41797.1 - 3.2e-09 36.5 5.9 5.6e-09 35.7 4.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFH41797.1 - 0.14 10.9 2.8 0.13 11.0 0.1 2.2 2 1 0 2 2 2 0 Fungal specific transcription factor domain PDT PF00800.13 KFH41798.1 - 1.2e-65 220.4 0.0 1.5e-65 220.1 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 KFH41798.1 - 1.1e-06 28.0 0.0 3e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 ACT domain Nuc_deoxyrib_tr PF05014.10 KFH41800.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase Tim17 PF02466.14 KFH41802.1 - 3e-25 88.7 4.1 4.4e-25 88.1 2.9 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Metallophos PF00149.23 KFH41803.1 - 2.3e-11 43.4 0.7 1.8e-06 27.4 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KFH41803.1 - 2.4e-10 40.4 0.0 4.5e-10 39.5 0.0 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Mhr1 PF12829.2 KFH41805.1 - 5.9e-25 86.9 0.1 9.1e-25 86.3 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination AAA_2 PF07724.9 KFH41807.1 - 1e-46 158.9 0.0 9e-45 152.6 0.0 3.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KFH41807.1 - 7.2e-28 97.4 0.0 3.6e-15 56.3 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KFH41807.1 - 1.3e-23 82.6 0.7 6.9e-23 80.3 0.5 2.4 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 KFH41807.1 - 3.7e-16 59.6 15.8 2e-06 27.9 0.0 6.6 3 2 3 6 6 5 2 AAA ATPase domain AAA_5 PF07728.9 KFH41807.1 - 3.9e-16 59.0 0.0 2.8e-10 40.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KFH41807.1 - 1.5e-13 50.9 0.1 4.1e-05 23.7 0.0 4.4 2 1 2 4 4 4 2 AAA domain AAA_17 PF13207.1 KFH41807.1 - 2.6e-09 37.9 2.2 0.0041 17.9 0.4 3.6 2 2 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 KFH41807.1 - 4.1e-09 36.1 0.0 4.9e-06 26.1 0.0 2.6 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.1 KFH41807.1 - 3.2e-08 33.5 0.0 0.0091 15.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KFH41807.1 - 3.8e-08 32.9 0.0 0.023 14.4 0.0 3.7 3 1 0 3 3 3 2 Part of AAA domain AAA_18 PF13238.1 KFH41807.1 - 1.6e-07 31.7 3.3 0.0027 17.9 0.1 4.2 3 2 2 5 5 3 2 AAA domain IstB_IS21 PF01695.12 KFH41807.1 - 9e-07 28.4 0.0 0.032 13.6 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Clp_N PF02861.15 KFH41807.1 - 1.1e-06 28.4 5.6 7.2e-05 22.6 0.3 4.0 4 0 0 4 4 4 1 Clp amino terminal domain Mg_chelatase PF01078.16 KFH41807.1 - 9.7e-06 24.8 0.1 0.19 10.8 0.0 3.6 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI MobB PF03205.9 KFH41807.1 - 1.4e-05 24.8 0.0 0.094 12.4 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 KFH41807.1 - 1.5e-05 24.8 12.8 0.0078 15.9 0.2 5.5 3 2 0 4 4 4 2 Archaeal ATPase AAA_28 PF13521.1 KFH41807.1 - 1.6e-05 24.9 0.0 0.24 11.3 0.0 3.4 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.17 KFH41807.1 - 3e-05 24.1 0.0 0.42 10.7 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.1 KFH41807.1 - 3.8e-05 23.5 0.1 0.2 11.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain T2SE PF00437.15 KFH41807.1 - 4.8e-05 22.3 1.2 0.0093 14.8 0.2 2.8 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.1 KFH41807.1 - 0.00014 21.3 0.2 0.92 8.8 0.0 3.9 3 1 0 4 4 4 2 AAA domain AAA_3 PF07726.6 KFH41807.1 - 0.00021 20.8 0.0 1.1 8.8 0.0 3.7 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 KFH41807.1 - 0.00039 20.7 0.4 0.7 10.1 0.0 3.5 3 0 0 3 3 3 1 ABC transporter ResIII PF04851.10 KFH41807.1 - 0.00042 20.1 0.2 0.35 10.6 0.0 3.8 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit DUF258 PF03193.11 KFH41807.1 - 0.00071 18.8 0.0 0.33 10.1 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Torsin PF06309.6 KFH41807.1 - 0.00092 19.0 0.0 0.0075 16.1 0.0 2.2 2 0 0 2 2 2 1 Torsin NACHT PF05729.7 KFH41807.1 - 0.0013 18.4 0.1 0.15 11.7 0.0 2.9 3 0 0 3 3 2 1 NACHT domain AAA_29 PF13555.1 KFH41807.1 - 0.0013 18.2 0.0 1 8.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain NTPase_1 PF03266.10 KFH41807.1 - 0.0028 17.3 0.0 0.22 11.2 0.0 3.3 3 0 0 3 3 3 1 NTPase AAA_24 PF13479.1 KFH41807.1 - 0.004 16.7 1.8 2 7.9 0.0 3.5 4 0 0 4 4 3 1 AAA domain AAA_23 PF13476.1 KFH41807.1 - 0.0057 17.0 10.1 0.8 9.9 0.2 4.1 3 1 0 3 3 3 1 AAA domain AAA_10 PF12846.2 KFH41807.1 - 0.0073 15.7 7.0 0.16 11.3 0.0 4.6 4 2 0 5 5 5 1 AAA-like domain SRP54 PF00448.17 KFH41807.1 - 0.011 15.1 0.0 4.6 6.6 0.0 3.1 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain AAA_21 PF13304.1 KFH41807.1 - 0.015 15.2 0.2 2.1 8.2 0.0 3.0 4 0 0 4 4 3 0 AAA domain UPF0079 PF02367.12 KFH41807.1 - 0.033 13.7 0.0 8.1 6.1 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ATP_bind_1 PF03029.12 KFH41807.1 - 0.049 13.1 0.0 7 6.1 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 KFH41807.1 - 0.12 12.3 0.1 1.8 8.5 0.0 3.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase V_ATPase_I PF01496.14 KFH41807.1 - 0.43 8.3 4.6 0.85 7.3 3.2 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Macoilin PF09726.4 KFH41807.1 - 1.3 7.2 8.9 2.8 6.1 6.2 1.5 1 0 0 1 1 1 0 Transmembrane protein Homeobox_KN PF05920.6 KFH41808.1 - 7.8e-18 63.8 0.1 3e-17 62.0 0.1 2.1 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KFH41808.1 - 0.00075 19.0 4.1 0.014 15.0 2.8 2.4 1 1 0 1 1 1 1 Homeobox domain INSIG PF07281.7 KFH41809.1 - 3.4e-46 157.0 1.2 4.2e-46 156.7 0.8 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) FAD-oxidase_C PF02913.14 KFH41810.1 - 5.5e-59 199.4 0.5 2.2e-58 197.4 0.1 1.9 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KFH41810.1 - 6.5e-36 122.8 0.0 1.3e-35 121.8 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain zf-Tim10_DDP PF02953.10 KFH41811.1 - 1.3e-22 78.8 2.5 1.5e-22 78.6 1.7 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 KFH41811.1 - 0.032 13.6 1.3 0.035 13.5 0.9 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) bZIP_1 PF00170.16 KFH41811.1 - 0.096 12.6 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 bZIP transcription factor RL11D PF11088.3 KFH41811.1 - 0.12 12.2 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 Mg_trans_NIPA PF05653.9 KFH41812.1 - 1.1e-86 290.5 22.5 1.4e-86 290.1 15.6 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KFH41812.1 - 7e-07 29.4 4.8 7e-07 29.4 3.3 3.5 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KFH41812.1 - 3.5e-05 23.8 8.0 3.5e-05 23.8 5.6 3.4 3 1 1 4 4 4 1 EamA-like transporter family Nuc_sug_transp PF04142.10 KFH41812.1 - 0.01 14.9 5.7 0.037 13.1 0.7 2.2 2 0 0 2 2 2 0 Nucleotide-sugar transporter Zein-binding PF04576.10 KFH41812.1 - 0.056 13.5 0.9 0.1 12.7 0.6 1.4 1 0 0 1 1 1 0 Zein-binding CAP_N PF01213.14 KFH41812.1 - 0.22 10.7 1.4 2.5 7.3 0.1 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal MFS_1 PF07690.11 KFH41813.1 - 5.3e-20 71.4 52.5 6.3e-18 64.6 35.9 2.7 1 1 0 1 1 1 1 Major Facilitator Superfamily ECH PF00378.15 KFH41814.1 - 3.1e-34 118.1 0.0 3.9e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family CDC45 PF02724.9 KFH41815.1 - 0.00026 19.1 3.8 0.00033 18.8 2.6 1.1 1 0 0 1 1 1 1 CDC45-like protein Aldedh PF00171.17 KFH41816.1 - 2.4e-141 471.2 0.1 2.8e-141 470.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Med3 PF11593.3 KFH41817.1 - 0.032 13.4 18.8 0.038 13.2 13.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal ORC6 PF05460.8 KFH41817.1 - 1.3 8.0 17.6 1.7 7.6 12.2 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF966 PF06136.8 KFH41817.1 - 1.4 8.2 16.2 1.8 7.8 11.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Mitofilin PF09731.4 KFH41817.1 - 7.1 5.1 11.7 8.7 4.8 8.1 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein TFIIA PF03153.8 KFH41817.1 - 8.3 6.1 24.3 11 5.8 16.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit QCR10 PF09796.4 KFH41818.1 - 2.4e-20 71.9 0.1 2.5e-20 71.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) SbcCD_C PF13558.1 KFH41819.1 - 2.6e-11 43.2 0.0 1.1e-10 41.2 0.0 2.2 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 KFH41819.1 - 2.3e-06 27.8 2.6 2.7e-05 24.2 1.8 2.7 1 1 0 1 1 1 1 AAA domain AAA_13 PF13166.1 KFH41819.1 - 3.9e-06 25.6 123.9 0.00052 18.6 25.4 6.4 1 1 3 5 5 5 4 AAA domain COG2 PF06148.6 KFH41819.1 - 3.1e-05 23.8 0.7 3.1e-05 23.8 0.5 9.5 3 2 5 9 9 9 2 COG (conserved oligomeric Golgi) complex component, COG2 AAA_23 PF13476.1 KFH41819.1 - 0.00031 21.1 4.4 0.00031 21.1 3.0 8.4 1 1 4 5 5 5 1 AAA domain FliJ PF02050.11 KFH41819.1 - 0.00068 19.6 0.1 0.00068 19.6 0.1 11.3 4 4 7 11 11 11 3 Flagellar FliJ protein Exonuc_VII_S PF02609.11 KFH41819.1 - 0.00076 19.1 0.4 0.00076 19.1 0.2 5.9 5 0 0 5 5 5 1 Exonuclease VII small subunit TMF_TATA_bd PF12325.3 KFH41819.1 - 0.0067 16.1 9.2 0.0067 16.1 6.4 10.8 6 4 4 10 10 10 1 TATA element modulatory factor 1 TATA binding DUF948 PF06103.6 KFH41819.1 - 0.06 13.2 0.1 0.06 13.2 0.1 9.0 7 2 2 9 9 9 0 Bacterial protein of unknown function (DUF948) DUF2946 PF11162.3 KFH41820.1 - 0.63 10.2 8.4 0.033 14.3 1.5 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2946) CENP-B_dimeris PF09026.5 KFH41820.1 - 1.2 9.3 20.6 0.37 11.0 5.0 2.8 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Macoilin PF09726.4 KFH41820.1 - 1.8 6.7 9.6 2.2 6.4 6.6 1.1 1 0 0 1 1 1 0 Transmembrane protein SGT1 PF07093.6 KFH41820.1 - 2.3 6.4 12.9 3.1 6.0 9.0 1.1 1 0 0 1 1 1 0 SGT1 protein BTV_NS2 PF04514.7 KFH41820.1 - 7.2 5.3 6.3 0.23 10.2 0.2 1.6 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 Tom22 PF04281.8 KFH41820.1 - 7.9 6.0 9.1 1.4 8.4 1.8 2.3 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 GATA PF00320.22 KFH41821.1 - 4.5e-16 57.9 5.5 7.8e-16 57.1 3.8 1.4 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 KFH41821.1 - 5.5e-15 55.2 0.0 1e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 KFH41821.1 - 5.2e-11 42.8 0.0 1.5e-10 41.3 0.0 1.8 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 KFH41821.1 - 2.1e-09 37.1 0.0 4e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 KFH41821.1 - 1.3e-05 25.2 0.0 2.2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.1 KFH41821.1 - 0.0023 17.8 0.0 0.004 17.1 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.1 KFH41821.1 - 0.02 14.7 0.0 0.07 13.0 0.0 1.9 1 0 0 1 1 1 0 PAS domain TF_Zn_Ribbon PF08271.7 KFH41821.1 - 0.14 11.5 0.8 0.79 9.0 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding DUF4428 PF14471.1 KFH41821.1 - 1.2 8.9 5.5 0.38 10.5 0.5 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) PPP4R2 PF09184.6 KFH41822.1 - 5.8e-12 45.7 0.0 5.8e-12 45.7 0.0 4.2 3 2 1 4 4 4 1 PPP4R2 EMP70 PF02990.11 KFH41823.1 - 9.9e-197 654.5 1.8 1.3e-196 654.1 1.3 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 NfeD PF01957.13 KFH41823.1 - 0.006 16.7 0.0 0.006 16.7 0.0 4.2 2 2 3 5 5 5 2 NfeD-like C-terminal, partner-binding DHO_dh PF01180.16 KFH41824.1 - 1e-65 221.6 0.0 1.4e-65 221.2 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase PcrB PF01884.12 KFH41824.1 - 9e-05 21.8 2.0 0.14 11.3 0.1 2.2 2 0 0 2 2 2 2 PcrB family FMN_dh PF01070.13 KFH41824.1 - 0.0012 17.8 1.3 0.07 11.9 0.8 2.3 2 0 0 2 2 2 2 FMN-dependent dehydrogenase Usp PF00582.21 KFH41824.1 - 0.087 13.0 0.8 0.21 11.7 0.1 2.0 2 0 0 2 2 2 0 Universal stress protein family Selenoprotein_S PF06936.6 KFH41825.1 - 0.28 10.6 9.7 0.6 9.6 6.7 1.5 1 0 0 1 1 1 0 Selenoprotein S (SelS) IATP PF04568.7 KFH41825.1 - 2.3 8.2 14.3 0.026 14.5 3.4 2.6 3 0 0 3 3 3 0 Mitochondrial ATPase inhibitor, IATP SPRY PF00622.23 KFH41826.1 - 0.048 13.7 0.0 0.12 12.5 0.0 1.6 2 0 0 2 2 2 0 SPRY domain CLTH PF10607.4 KFH41828.1 - 2.4e-29 101.9 0.0 4.4e-29 101.0 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 KFH41828.1 - 8.7e-13 47.7 0.2 1.8e-12 46.7 0.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 KFH41828.1 - 0.002 18.1 0.6 0.0038 17.2 0.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFH41828.1 - 0.0021 17.8 0.3 0.0035 17.1 0.2 1.4 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.7 KFH41828.1 - 0.004 16.3 0.0 0.0065 15.7 0.0 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4_3 PF13920.1 KFH41828.1 - 0.018 14.7 0.2 0.031 13.9 0.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) AIP3 PF03915.8 KFH41828.1 - 0.066 12.1 0.1 0.17 10.7 0.1 1.6 1 1 0 1 1 1 0 Actin interacting protein 3 zf-RING_5 PF14634.1 KFH41828.1 - 0.067 12.9 0.3 0.13 11.9 0.2 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 KFH41828.1 - 0.1 12.2 0.5 0.2 11.3 0.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) U-box PF04564.10 KFH41831.1 - 4.7e-16 58.4 0.0 8e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.1 KFH41831.1 - 3.9e-15 55.2 7.4 1.8e-14 53.1 0.7 2.9 1 1 2 3 3 3 2 TPR repeat TPR_1 PF00515.23 KFH41831.1 - 2.6e-08 33.1 2.8 0.00084 18.8 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFH41831.1 - 2e-07 31.4 6.5 7e-05 23.3 0.0 3.8 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFH41831.1 - 6.2e-06 25.7 5.1 0.017 15.0 0.3 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 KFH41831.1 - 0.0041 16.9 6.6 1.5 8.8 0.0 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFH41831.1 - 0.0047 16.7 2.0 0.0054 16.5 0.0 2.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFH41831.1 - 0.012 15.7 2.2 0.43 10.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat CDC37_N PF03234.9 KFH41831.1 - 0.048 13.9 2.1 0.078 13.2 1.4 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding TPR_12 PF13424.1 KFH41831.1 - 0.06 13.2 7.8 0.091 12.7 0.2 3.3 1 1 3 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFH41831.1 - 0.062 13.9 5.0 5.9 7.8 0.0 4.1 2 1 2 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 KFH41831.1 - 0.079 13.0 2.5 0.22 11.6 0.2 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KFH41831.1 - 1.7 8.6 4.1 2.3 8.2 0.0 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat p450 PF00067.17 KFH41832.1 - 1.9e-49 168.4 0.0 1e-27 96.8 0.0 3.1 3 0 0 3 3 3 3 Cytochrome P450 DIE2_ALG10 PF04922.7 KFH41834.1 - 7.4e-78 262.2 21.6 1.5e-58 198.6 1.9 3.2 3 0 0 3 3 3 3 DIE2/ALG10 family Amidase PF01425.16 KFH41835.1 - 1e-59 202.5 0.0 1.4e-59 202.1 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF3759 PF12585.3 KFH41836.1 - 0.078 12.8 4.2 0.26 11.2 2.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3759) Cutinase PF01083.17 KFH41837.1 - 8.8e-41 139.5 1.3 1.3e-40 139.0 0.9 1.2 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 KFH41837.1 - 2.6e-05 23.7 0.1 6.6e-05 22.4 0.1 1.7 1 1 0 1 1 1 1 PE-PPE domain LIP PF03583.9 KFH41837.1 - 0.004 16.4 0.4 0.0063 15.7 0.3 1.3 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 KFH41837.1 - 0.0048 16.6 0.1 0.0071 16.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFH41837.1 - 0.015 14.8 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold UPF0183 PF03676.9 KFH41838.1 - 6.3e-37 127.0 0.0 2.3e-22 79.1 0.0 4.8 4 1 0 4 4 4 4 Uncharacterised protein family (UPF0183) AAA_13 PF13166.1 KFH41839.1 - 0.0036 15.8 0.1 0.0054 15.2 0.1 1.1 1 0 0 1 1 1 1 AAA domain PG_binding_1 PF01471.13 KFH41839.1 - 0.012 15.5 0.0 2.4 8.2 0.0 3.1 3 0 0 3 3 3 0 Putative peptidoglycan binding domain Med4 PF10018.4 KFH41840.1 - 1.5e-37 128.8 21.7 4.9e-37 127.1 15.1 1.9 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 MAP7 PF05672.6 KFH41840.1 - 0.0021 17.4 30.2 0.004 16.5 20.9 1.4 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family Myc_N PF01056.13 KFH41840.1 - 0.0047 16.1 5.2 0.0065 15.6 3.1 1.6 1 1 0 1 1 1 1 Myc amino-terminal region ERM PF00769.14 KFH41840.1 - 0.022 14.3 20.5 0.04 13.4 12.3 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF3027 PF11228.3 KFH41840.1 - 0.047 13.3 1.1 0.089 12.4 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3027) Reo_sigmaC PF04582.7 KFH41840.1 - 0.057 12.5 0.2 0.084 12.0 0.2 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein AAA_11 PF13086.1 KFH41840.1 - 0.82 9.2 4.8 0.61 9.6 1.1 1.9 2 0 0 2 2 2 0 AAA domain TFIIA PF03153.8 KFH41840.1 - 1.1 9.1 13.1 1.6 8.5 9.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nucleo_P87 PF07267.6 KFH41840.1 - 2.8 6.5 7.4 1.4 7.5 3.6 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 ASF1_hist_chap PF04729.8 KFH41841.1 - 7.5e-67 223.7 0.1 1e-66 223.3 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Piwi PF02171.12 KFH41842.1 - 1.5e-78 263.8 0.0 2.2e-78 263.2 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 KFH41842.1 - 7.7e-17 60.8 0.0 1.4e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 KFH41842.1 - 1.1e-08 34.2 0.0 3e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) bPH_4 PF06713.6 KFH41842.1 - 0.11 12.3 0.0 0.45 10.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial PH domain PAP2 PF01569.16 KFH41843.1 - 1.5e-13 50.5 7.0 1.5e-13 50.5 4.9 2.7 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 KFH41843.1 - 4.2e-08 32.9 7.2 4.2e-08 32.9 5.0 2.4 2 2 0 2 2 2 1 PAP2 superfamily SHMT PF00464.14 KFH41845.1 - 5.7e-205 680.2 0.0 7.1e-205 679.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.14 KFH41845.1 - 1.6e-05 23.8 0.0 2.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KFH41845.1 - 8.1e-05 21.7 0.0 0.00026 20.0 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KFH41845.1 - 0.007 15.5 0.0 0.0095 15.1 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase RRM_1 PF00076.17 KFH41846.1 - 1.7e-08 33.9 0.0 3.2e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH41846.1 - 1.3e-07 31.4 0.0 5e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH41846.1 - 0.00013 21.7 0.0 0.0003 20.5 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) APOBEC_C PF05240.9 KFH41846.1 - 0.28 10.6 0.4 0.53 9.7 0.3 1.4 1 0 0 1 1 1 0 APOBEC-like C-terminal domain IBR PF01485.16 KFH41847.1 - 4.6e-22 77.6 41.8 3.7e-11 42.7 3.9 4.5 3 1 1 4 4 4 2 IBR domain zf-C3HC4_2 PF13923.1 KFH41847.1 - 7.4e-07 29.0 6.6 7.4e-07 29.0 4.6 4.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFH41847.1 - 2.6e-05 23.7 4.8 2.6e-05 23.7 3.3 4.6 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFH41847.1 - 8.8e-05 22.2 6.2 8.8e-05 22.2 4.3 3.6 3 0 0 3 3 3 2 Ring finger domain zf-RING_5 PF14634.1 KFH41847.1 - 0.0015 18.2 6.5 0.0015 18.2 4.5 4.1 2 1 1 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KFH41847.1 - 0.027 14.1 1.9 0.027 14.1 1.3 3.6 3 0 0 3 3 3 0 RING-type zinc-finger UN_NPL4 PF11543.3 KFH41847.1 - 0.072 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Trp_syntA PF00290.15 KFH41847.1 - 0.22 10.0 0.0 0.33 9.4 0.0 1.2 1 0 0 1 1 1 0 Tryptophan synthase alpha chain Y_phosphatase PF00102.22 KFH41848.1 - 1.5e-50 171.7 0.0 3.6e-50 170.4 0.0 1.6 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KFH41848.1 - 8.6e-05 22.6 0.0 0.00018 21.6 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KFH41848.1 - 0.0014 18.8 0.0 0.0037 17.5 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family Sporozoite_P67 PF05642.6 KFH41848.1 - 0.0033 15.3 2.5 0.0042 15.0 1.7 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen DSPc PF00782.15 KFH41848.1 - 0.017 14.6 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Mucin PF01456.12 KFH41848.1 - 0.054 13.2 16.3 0.09 12.5 11.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.3 KFH41848.1 - 0.38 10.5 9.3 0.28 10.9 5.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) LAT PF15234.1 KFH41848.1 - 0.49 9.8 7.3 0.16 11.4 0.8 2.3 1 1 1 2 2 2 0 Linker for activation of T-cells Dicty_REP PF05086.7 KFH41848.1 - 0.83 7.3 3.6 1.1 6.9 2.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.6 KFH41848.1 - 3.5 5.4 14.6 4.9 5.0 10.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RasGAP PF00616.14 KFH41849.1 - 9.4e-49 165.7 0.2 4.4e-48 163.5 0.0 2.1 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 KFH41849.1 - 1.1e-29 102.9 4.3 1.1e-29 102.9 3.0 2.9 4 0 0 4 4 4 1 RasGAP C-terminus DUF4287 PF14117.1 KFH41849.1 - 0.092 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4287) CENP-F_leu_zip PF10473.4 KFH41849.1 - 2.2 8.1 10.9 0.44 10.3 1.0 2.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1645 PF07816.6 KFH41849.1 - 3.3 8.1 7.3 1.8 8.9 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) DUF972 PF06156.8 KFH41849.1 - 5.3 7.4 11.3 5.9 7.2 0.9 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF972) VanZ PF04892.7 KFH41850.1 - 5.8e-13 48.9 2.7 7.9e-13 48.5 1.9 1.1 1 0 0 1 1 1 1 VanZ like family DUF4401 PF14351.1 KFH41850.1 - 0.0069 15.4 0.9 0.01 14.8 0.6 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4401) RseC_MucC PF04246.7 KFH41850.1 - 0.087 12.3 0.2 3.1 7.3 0.0 2.1 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Frag1 PF10277.4 KFH41850.1 - 0.11 11.9 1.6 0.15 11.5 0.6 1.6 2 0 0 2 2 2 0 Frag1/DRAM/Sfk1 family Arteri_Gl PF00951.13 KFH41850.1 - 0.19 11.3 1.6 0.27 10.8 1.1 1.2 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein DUF4345 PF14248.1 KFH41850.1 - 0.21 11.0 1.6 12 5.4 0.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4345) MAM33 PF02330.11 KFH41851.1 - 1.6e-31 109.7 1.7 1.6e-30 106.4 1.2 1.9 1 1 0 1 1 1 1 Mitochondrial glycoprotein Clp1 PF06807.9 KFH41852.1 - 1.1e-11 44.9 0.0 2.2e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 KFH41852.1 - 0.00078 19.1 0.0 0.004 16.8 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 KFH41852.1 - 0.1 13.4 0.0 0.28 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain RNA_polI_A34 PF08208.6 KFH41854.1 - 1.9e-30 106.0 11.5 1.9e-30 106.0 8.0 6.9 3 2 2 5 5 5 1 DNA-directed RNA polymerase I subunit RPA34.5 Suf PF05843.9 KFH41855.1 - 6.7e-78 262.2 0.4 4.8e-76 256.1 0.0 3.4 3 1 0 3 3 3 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 KFH41855.1 - 2.7e-05 24.4 0.5 0.21 12.3 0.1 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFH41855.1 - 0.00029 21.4 0.2 0.0011 19.5 0.1 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat HrpJ PF07201.6 KFH41855.1 - 0.007 16.3 0.0 1.3 8.9 0.0 2.9 2 0 0 2 2 2 1 HrpJ-like domain HAT PF02184.11 KFH41855.1 - 0.057 13.1 0.3 0.5 10.1 0.1 2.5 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat DUF3467 PF11950.3 KFH41855.1 - 0.082 12.9 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3467) DUF1772 PF08592.6 KFH41856.1 - 0.031 13.9 0.5 0.045 13.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Mucin PF01456.12 KFH41856.1 - 2.5 7.8 12.6 10 5.8 5.1 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Pkinase PF00069.20 KFH41857.1 - 3.6e-69 232.8 0.0 4.5e-69 232.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH41857.1 - 2.7e-29 102.0 0.0 3.6e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH41857.1 - 1.3e-06 27.5 0.0 1.9e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFH41857.1 - 0.00056 19.7 0.0 0.00088 19.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KFH41857.1 - 0.00061 18.9 0.0 0.0011 18.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KFH41857.1 - 0.025 13.9 0.0 0.058 12.7 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL CorA PF01544.13 KFH41858.1 - 7.2e-15 54.7 0.1 1.4e-14 53.8 0.1 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein CCDC155 PF14662.1 KFH41858.1 - 0.026 14.1 0.1 0.026 14.1 0.1 1.8 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 DivIVA PF05103.8 KFH41858.1 - 0.21 11.6 5.1 1.6 8.7 0.1 2.6 3 0 0 3 3 3 0 DivIVA protein DivIC PF04977.10 KFH41858.1 - 5.6 6.5 6.9 1.7 8.1 0.2 2.9 3 0 0 3 3 3 0 Septum formation initiator Ferric_reduct PF01794.14 KFH41859.1 - 7.3e-14 51.9 9.7 7.3e-14 51.9 6.7 2.0 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KFH41859.1 - 1.3e-10 41.4 0.0 1.1e-09 38.3 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KFH41859.1 - 7.4e-08 32.2 0.0 1.6e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 KFH41859.1 - 3.3e-05 24.3 0.0 0.14 12.6 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain RF-1 PF00472.15 KFH41860.1 - 1.9e-14 53.3 2.7 2.8e-14 52.8 1.9 1.2 1 0 0 1 1 1 1 RF-1 domain UPF0300 PF08594.5 KFH41860.1 - 0.027 13.4 0.1 0.046 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0300) Hormone_1 PF00103.15 KFH41860.1 - 0.047 13.0 0.2 0.059 12.7 0.1 1.1 1 0 0 1 1 1 0 Somatotropin hormone family TMF_TATA_bd PF12325.3 KFH41860.1 - 0.06 13.0 3.8 0.095 12.4 2.6 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding XPG_I PF00867.13 KFH41861.1 - 2.2e-25 88.5 0.0 4.6e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KFH41861.1 - 5.5e-06 26.5 0.0 1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 KFH41861.1 - 0.00039 19.9 0.3 0.00085 18.8 0.0 1.7 2 0 0 2 2 2 1 XPG domain containing TPR_11 PF13414.1 KFH41861.1 - 0.0092 15.6 0.0 0.022 14.3 0.0 1.6 1 0 0 1 1 1 1 TPR repeat 5_3_exonuc PF01367.15 KFH41861.1 - 0.025 14.7 0.0 0.064 13.4 0.0 1.6 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold TPR_2 PF07719.12 KFH41861.1 - 0.15 12.0 0.0 0.45 10.5 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Redoxin PF08534.5 KFH41863.1 - 2.8e-24 85.3 0.0 3.3e-24 85.1 0.0 1.0 1 0 0 1 1 1 1 Redoxin Bromodomain PF00439.20 KFH41864.1 - 2.3e-18 65.8 0.8 5.5e-18 64.6 0.1 2.0 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.8 KFH41864.1 - 1.6e-12 47.0 0.1 3.6e-12 45.8 0.1 1.6 1 0 0 1 1 1 1 Bromodomain associated DndB PF14072.1 KFH41864.1 - 0.028 13.5 2.3 1.1 8.3 0.0 2.3 2 0 0 2 2 2 0 DNA-sulfur modification-associated Oxysterol_BP PF01237.13 KFH41865.1 - 2.6e-53 180.7 0.0 4.6e-42 143.7 0.0 2.4 2 1 0 2 2 2 2 Oxysterol-binding protein DUF2962 PF11176.3 KFH41866.1 - 1e-34 119.3 7.2 1.3e-25 89.7 0.1 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF2962) FluMu_gp41 PF10109.4 KFH41866.1 - 0.063 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Mu-like prophage FluMu protein gp41 Lgl_C PF08596.5 KFH41868.1 - 9.8e-121 402.9 0.0 2e-120 401.9 0.0 1.5 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 KFH41868.1 - 4.1e-06 26.4 2.5 0.019 14.8 0.2 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat TAA-Trp-ring PF15401.1 KFH41868.1 - 0.041 14.1 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Tryptophan-ring motif of head of Trimeric autotransporter adhesin APH PF01636.18 KFH41870.1 - 1.1e-23 84.2 0.1 1.4e-23 83.8 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFH41870.1 - 0.002 17.5 0.0 0.19 11.0 0.0 2.1 2 0 0 2 2 2 2 RIO1 family Choline_kinase PF01633.15 KFH41870.1 - 0.0023 17.5 0.0 0.0034 16.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 KFH41870.1 - 0.061 12.2 0.0 1.2 8.0 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase MaoC_dehydrat_N PF13452.1 KFH41871.1 - 0.0025 17.5 0.0 0.089 12.5 0.0 2.3 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase MaoC_dehydratas PF01575.14 KFH41871.1 - 0.1 11.9 0.0 0.32 10.3 0.0 1.7 2 0 0 2 2 2 0 MaoC like domain OmdA PF13376.1 KFH41873.1 - 1.1e-15 56.9 0.2 2.3e-15 55.9 0.1 1.5 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated GST_N_2 PF13409.1 KFH41874.1 - 1.6e-21 76.0 0.0 3.3e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFH41874.1 - 4.6e-14 52.0 0.0 1.5e-13 50.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KFH41874.1 - 2.7e-05 24.3 0.0 0.00035 20.7 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFH41874.1 - 3.8e-05 23.5 0.0 7.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFH41874.1 - 0.0002 21.8 0.0 0.00044 20.6 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RskA PF10099.4 KFH41876.1 - 7.7 6.2 9.3 0.57 9.8 0.5 2.3 1 1 1 2 2 2 0 Anti-sigma-K factor rskA ECH PF00378.15 KFH41878.1 - 1.2e-41 142.4 0.0 1.8e-41 141.8 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 KFH41878.1 - 0.02 14.6 0.4 0.074 12.8 0.0 1.8 2 0 0 2 2 2 0 Peptidase family S49 Ank_2 PF12796.2 KFH41879.1 - 3e-39 133.2 1.6 2.6e-19 69.3 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFH41879.1 - 2e-27 93.5 0.1 6.8e-09 35.0 0.0 4.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 KFH41879.1 - 2e-20 72.3 1.7 7.3e-12 45.1 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFH41879.1 - 2.7e-19 69.1 3.2 1.1e-08 35.3 0.0 3.9 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFH41879.1 - 3.8e-18 63.7 0.0 1.7e-05 24.5 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Syntaxin PF00804.20 KFH41879.1 - 0.0044 17.1 0.7 0.0044 17.1 0.5 1.8 2 0 0 2 2 2 1 Syntaxin TMP_2 PF06791.8 KFH41879.1 - 0.023 14.3 2.0 0.042 13.4 1.4 1.3 1 0 0 1 1 1 0 Prophage tail length tape measure protein WXG100 PF06013.7 KFH41879.1 - 0.027 14.4 0.3 0.027 14.4 0.2 2.3 3 0 0 3 3 3 0 Proteins of 100 residues with WXG HisKA_3 PF07730.8 KFH41879.1 - 1.7 9.0 6.9 5.4 7.4 0.2 4.1 3 1 1 4 4 4 0 Histidine kinase Hydantoinase_B PF02538.9 KFH41881.1 - 2.1e-181 603.7 0.0 2.9e-181 603.2 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KFH41881.1 - 1.2e-81 273.9 0.0 2.5e-81 272.9 0.0 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KFH41881.1 - 5.8e-57 192.0 0.2 2.1e-55 186.9 0.0 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Glyco_hydro_25 PF01183.15 KFH41882.1 - 1e-45 155.7 2.5 1.2e-45 155.5 1.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 HAMP PF00672.20 KFH41883.1 - 1.2e-46 156.6 17.3 4.3e-11 42.8 0.1 7.8 7 0 0 7 7 7 6 HAMP domain HATPase_c PF02518.21 KFH41883.1 - 9.4e-28 96.1 0.4 9.4e-28 96.1 0.3 3.1 3 1 1 4 4 4 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KFH41883.1 - 2.2e-26 92.0 1.3 1.1e-25 89.7 0.6 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 KFH41883.1 - 3.7e-19 68.4 5.1 1e-18 67.0 0.3 3.9 4 0 0 4 4 3 1 His Kinase A (phospho-acceptor) domain DUF883 PF05957.8 KFH41883.1 - 0.0012 19.2 9.1 1.9 8.9 0.2 5.8 4 2 2 6 6 6 1 Bacterial protein of unknown function (DUF883) TSC22 PF01166.13 KFH41883.1 - 0.0064 16.4 6.7 15 5.6 0.0 5.8 6 0 0 6 6 6 0 TSC-22/dip/bun family Pox_A_type_inc PF04508.7 KFH41883.1 - 0.01 15.5 2.7 15 5.7 0.2 5.2 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat IF2_assoc PF08364.6 KFH41883.1 - 0.11 12.5 0.4 16 5.5 0.0 2.6 2 0 0 2 2 2 0 Bacterial translation initiation factor IF-2 associated region CENP-F_leu_zip PF10473.4 KFH41883.1 - 0.14 11.9 15.1 22 4.9 0.0 6.2 5 1 0 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2877 PF11392.3 KFH41883.1 - 0.17 12.0 4.9 4.7 7.4 0.0 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2877) MxiH PF09392.5 KFH41883.1 - 1.6 9.3 7.9 35 5.0 0.1 5.1 4 1 1 5 5 5 0 Type III secretion needle MxiH like NAAA-beta PF15508.1 KFH41883.1 - 2.3 8.6 6.4 6.2 7.2 0.1 4.9 6 2 1 7 7 7 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase MFS_1 PF07690.11 KFH41884.1 - 2.1e-38 131.9 22.1 6.4e-38 130.3 15.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 KFH41884.1 - 1.3e-06 27.1 0.1 1.3e-06 27.1 0.1 2.5 2 1 1 3 3 3 1 MFS/sugar transport protein Pkinase PF00069.20 KFH41885.1 - 1.4e-20 73.5 0.0 1.9e-20 73.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH41885.1 - 4.4e-09 35.7 0.0 5.4e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Bac_rhamnosid PF05592.6 KFH41889.1 - 1.7e-36 125.5 1.2 3.8e-15 55.1 0.0 3.0 3 0 0 3 3 3 3 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 KFH41889.1 - 1.8e-07 30.2 0.1 2.9e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 GDE_C PF06202.9 KFH41889.1 - 0.0006 18.6 0.0 0.012 14.3 0.0 2.1 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase SsgA PF04686.7 KFH41889.1 - 0.039 13.6 0.0 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 Streptomyces sporulation and cell division protein, SsgA HD PF01966.17 KFH41891.1 - 0.0001 22.3 0.0 0.00018 21.5 0.0 1.4 1 0 0 1 1 1 1 HD domain MFS_1 PF07690.11 KFH41892.1 - 7.4e-38 130.1 61.7 1.3e-28 99.7 19.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1304 PF06993.7 KFH41892.1 - 1.7 8.3 8.3 1.9 8.2 1.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1304) FAD_binding_4 PF01565.18 KFH41893.1 - 4.6e-24 84.4 0.5 8.6e-24 83.5 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFH41893.1 - 0.027 14.3 0.5 0.12 12.2 0.0 2.4 2 0 0 2 2 2 0 Berberine and berberine like tRNA-synt_2c PF01411.14 KFH41894.1 - 1.2e-09 37.0 0.0 1.4e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KFH41894.1 - 2.6e-05 23.9 0.1 5.3e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Glyco_hydro_61 PF03443.9 KFH41895.1 - 5.5e-78 261.7 0.0 6.3e-78 261.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.4 KFH41895.1 - 0.011 15.7 0.0 0.22 11.6 0.0 2.4 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase HAD PF12710.2 KFH41896.1 - 8.6e-09 35.8 0.0 1.4e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Fungal_trans PF04082.13 KFH41897.1 - 4.2e-25 88.1 0.0 8.8e-25 87.0 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH41897.1 - 5e-06 26.3 9.8 8.2e-06 25.6 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tim17 PF02466.14 KFH41899.1 - 1.9e-19 69.9 0.0 2.7e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family BPD_transp_2 PF02653.11 KFH41899.1 - 0.027 13.4 0.1 0.036 13.0 0.1 1.2 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component Dickkopf_N PF04706.7 KFH41901.1 - 0.094 12.8 4.9 0.26 11.4 3.4 1.7 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Zn_clus PF00172.13 KFH41901.1 - 0.47 10.4 5.7 0.98 9.3 3.9 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain GMP_synt_C PF00958.17 KFH41902.1 - 3.3e-29 100.4 0.0 5.7e-29 99.6 0.0 1.4 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 KFH41902.1 - 6.5e-16 58.3 0.0 1.5e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 KFH41902.1 - 5e-08 32.1 0.0 1.6e-05 23.9 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Asn_synthase PF00733.16 KFH41902.1 - 0.0012 18.3 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.11 KFH41902.1 - 0.0036 15.9 0.1 0.007 14.9 0.0 1.5 2 0 0 2 2 2 1 tRNA methyl transferase PAPS_reduct PF01507.14 KFH41902.1 - 0.015 15.1 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ThiI PF02568.9 KFH41902.1 - 0.017 14.5 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.14 KFH41902.1 - 0.023 13.7 0.0 0.039 12.9 0.0 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase ATP_bind_3 PF01171.15 KFH41902.1 - 0.028 13.8 0.0 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 PP-loop family QueC PF06508.8 KFH41902.1 - 0.037 13.3 0.0 0.13 11.4 0.0 1.8 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Peptidase_C26 PF07722.8 KFH41902.1 - 0.091 12.1 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Peptidase C26 NDUFB10 PF10249.4 KFH41903.1 - 0.002 18.2 0.0 0.0025 17.9 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 DUF3536 PF12055.3 KFH41903.1 - 0.086 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3536) Homeobox PF00046.24 KFH41904.1 - 1.9e-15 56.1 2.9 4.1e-15 55.1 2.0 1.6 1 0 0 1 1 1 1 Homeobox domain MAP7 PF05672.6 KFH41904.1 - 0.062 12.6 12.6 0.1 11.9 8.8 1.2 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Homeobox_KN PF05920.6 KFH41904.1 - 2.3 7.9 7.5 0.091 12.4 0.6 2.1 2 0 0 2 2 2 0 Homeobox KN domain Annexin PF00191.15 KFH41905.1 - 1.1e-70 233.4 1.2 2e-19 69.2 0.0 4.3 4 0 0 4 4 4 4 Annexin DUF3574 PF12098.3 KFH41905.1 - 0.0074 15.8 0.2 9.8 5.8 0.0 3.7 4 0 0 4 4 4 2 Protein of unknown function (DUF3574) Acetyltransf_11 PF13720.1 KFH41905.1 - 0.21 11.8 2.1 97 3.2 0.0 3.8 4 0 0 4 4 4 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 GKAP PF03359.8 KFH41906.1 - 0.48 9.9 4.9 0.64 9.5 3.4 1.1 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein DUF566 PF04484.7 KFH41906.1 - 2.7 7.3 6.1 3.3 7.1 4.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) F-box-like PF12937.2 KFH41907.1 - 0.00063 19.4 0.1 0.0024 17.5 0.1 2.1 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KFH41907.1 - 0.011 15.2 8.0 0.11 12.2 0.1 3.8 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFH41907.1 - 0.041 13.6 5.2 2.5 7.8 0.8 2.9 2 0 0 2 2 2 0 Leucine rich repeat LRR_6 PF13516.1 KFH41907.1 - 0.95 9.7 4.9 3.3 8.0 0.0 3.9 4 1 1 5 5 5 0 Leucine Rich repeat WH2 PF02205.15 KFH41908.1 - 1.8e-09 36.8 0.5 5.3e-09 35.3 0.4 1.9 1 0 0 1 1 1 1 WH2 motif DUF4243 PF14027.1 KFH41909.1 - 9.2e-73 245.5 0.3 1.1e-72 245.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) AICARFT_IMPCHas PF01808.13 KFH41911.1 - 2.2e-112 375.2 0.0 2.9e-112 374.8 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 KFH41911.1 - 4.4e-24 84.2 0.0 7.9e-24 83.4 0.0 1.4 1 0 0 1 1 1 1 MGS-like domain PCI PF01399.22 KFH41913.1 - 2.5e-14 53.4 0.0 3.6e-13 49.7 0.0 2.7 2 1 0 2 2 2 1 PCI domain RPN7 PF10602.4 KFH41913.1 - 6.1e-05 22.4 0.6 0.00013 21.3 0.4 1.5 1 1 0 1 1 1 1 26S proteasome subunit RPN7 DNA_pol_B_palm PF14792.1 KFH41914.1 - 5.6e-35 119.7 0.0 1.5e-34 118.4 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 KFH41914.1 - 2.8e-21 74.9 0.1 9.6e-21 73.2 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 KFH41914.1 - 9e-21 73.1 1.1 1.6e-20 72.3 0.8 1.4 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 KFH41914.1 - 2.6e-17 62.7 0.3 6.3e-17 61.5 0.1 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 KFH41914.1 - 0.0065 16.7 0.0 0.016 15.5 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain zf-C2H2 PF00096.21 KFH41915.1 - 0.54 10.7 13.6 0.29 11.5 2.2 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type APH PF01636.18 KFH41916.1 - 3.1e-14 53.2 2.8 9e-14 51.7 1.9 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFH41916.1 - 0.055 13.0 0.0 0.092 12.3 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase RRM_1 PF00076.17 KFH41917.1 - 1.6e-26 91.7 0.1 2.8e-19 68.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH41917.1 - 7.2e-21 73.9 0.1 2.6e-14 52.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH41917.1 - 5e-07 29.4 0.0 9.1e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Asn_synthase PF00733.16 KFH41918.1 - 1.6e-54 185.0 0.0 2.2e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KFH41918.1 - 3.8e-10 39.5 0.0 1.2e-09 37.9 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KFH41918.1 - 7.1e-08 32.4 0.0 1.6e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain BTB PF00651.26 KFH41919.1 - 0.00028 20.8 0.0 0.00074 19.4 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Med3 PF11593.3 KFH41919.1 - 0.079 12.1 5.5 0.024 13.8 0.6 1.9 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DUF3439 PF11921.3 KFH41919.1 - 0.42 10.3 9.6 0.82 9.4 6.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 KFH41919.1 - 2.6 5.6 4.1 3.6 5.2 2.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ppx-GppA PF02541.11 KFH41920.1 - 4.5e-27 94.9 0.0 1.6e-26 93.2 0.0 1.7 1 1 0 1 1 1 1 Ppx/GppA phosphatase family GATase PF00117.23 KFH41922.1 - 9.1e-10 38.2 0.0 9.1e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Spo12 PF05032.7 KFH41922.1 - 0.082 12.5 0.4 0.21 11.2 0.1 1.8 2 0 0 2 2 2 0 Spo12 family Peptidase_C26 PF07722.8 KFH41922.1 - 0.12 11.8 1.1 0.35 10.2 0.2 1.8 1 1 1 2 2 2 0 Peptidase C26 DUF605 PF04652.11 KFH41923.1 - 5.1 6.3 12.7 5.9 6.1 8.8 1.2 1 0 0 1 1 1 0 Vta1 like HpaP PF09483.5 KFH41923.1 - 5.9 6.8 10.5 11 5.8 4.1 2.3 2 0 0 2 2 2 0 Type III secretion protein (HpaP) Ribosomal_L37 PF08561.5 KFH41925.1 - 1.9e-27 94.6 3.0 1.1e-26 92.2 2.1 1.9 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 HECT_2 PF09814.4 KFH41926.1 - 6.2e-43 146.8 0.1 4.1e-42 144.1 0.1 2.0 1 1 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding SNF2_N PF00176.18 KFH41926.1 - 1.4e-34 119.2 0.0 1e-31 109.8 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain DEAD PF00270.24 KFH41926.1 - 1.1e-05 24.9 0.0 2.3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFH41926.1 - 0.01 15.7 0.1 0.021 14.6 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain DNA_RNApol_7kD PF03604.8 KFH41926.1 - 0.064 12.7 1.4 0.079 12.4 0.1 1.8 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit ResIII PF04851.10 KFH41926.1 - 0.066 13.0 0.0 15 5.3 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Rad17 PF03215.10 KFH41928.1 - 2.9e-59 201.1 0.0 4.5e-59 200.4 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA PF00004.24 KFH41928.1 - 0.032 14.4 0.0 0.089 12.9 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFH41928.1 - 0.079 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KFH41928.1 - 0.18 10.8 0.0 0.36 9.8 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Seryl_tRNA_N PF02403.17 KFH41929.1 - 0.0025 17.8 3.2 0.0047 16.9 2.2 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain TBPIP PF07106.8 KFH41929.1 - 0.12 11.9 4.8 0.18 11.3 3.3 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Viral_P18 PF04521.8 KFH41929.1 - 5.5 6.4 7.2 0.89 9.0 0.6 2.1 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein PLDc_3 PF13918.1 KFH41930.1 - 0.062 12.7 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 PLD-like domain TFIIA PF03153.8 KFH41930.1 - 4.6 7.0 6.3 6 6.6 4.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lipase_GDSL_2 PF13472.1 KFH41931.1 - 1.9e-21 77.0 0.0 2.8e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFH41931.1 - 4.7e-07 29.8 0.1 0.0022 17.8 0.0 2.2 1 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase Cpn60_TCP1 PF00118.19 KFH41932.1 - 4.8e-135 450.9 7.8 5.7e-135 450.6 5.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RabGAP-TBC PF00566.13 KFH41933.1 - 3.1e-29 101.9 0.0 5.2e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SNF2_N PF00176.18 KFH41934.1 - 1.7e-74 250.3 0.4 2.9e-74 249.5 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFH41934.1 - 1.2e-14 53.9 0.0 4.2e-14 52.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFH41934.1 - 2.9e-08 33.7 0.0 6.2e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KFH41934.1 - 9.5e-05 21.9 0.0 0.00019 20.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 KFH41934.1 - 0.00091 18.1 0.1 0.32 9.7 0.0 2.8 3 0 0 3 3 3 2 Class II histone deacetylase complex subunits 2 and 3 DEAD_2 PF06733.10 KFH41934.1 - 0.14 11.5 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 HSA PF07529.8 KFH41934.1 - 0.36 10.6 14.0 0.031 14.0 5.9 2.1 2 0 0 2 2 2 0 HSA FA_desaturase PF00487.19 KFH41935.1 - 1.9e-25 89.7 15.8 2.8e-25 89.2 11.0 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KFH41935.1 - 3.4e-09 36.8 0.2 7.5e-09 35.7 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Zn_clus PF00172.13 KFH41936.1 - 4e-08 33.0 11.1 9.2e-08 31.8 7.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFH41936.1 - 3.7e-05 22.5 1.4 3.7e-05 22.5 1.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 KFH41937.1 - 3.1e-26 91.7 0.0 5.4e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidase PF01425.16 KFH41937.1 - 1.7e-23 83.2 0.0 3.1e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Amidase Ilm1 PF10311.4 KFH41938.1 - 5.3e-56 188.6 0.2 6.1e-56 188.4 0.2 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Ribonuc_2-5A PF06479.7 KFH41939.1 - 5.5e-44 149.1 0.0 9.8e-44 148.3 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 KFH41939.1 - 1.3e-42 145.7 0.0 2e-42 145.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH41939.1 - 4.4e-21 75.1 0.0 3.6e-20 72.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.1 KFH41939.1 - 2.6e-06 27.0 0.1 5.9e-05 22.6 0.0 2.6 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.16 KFH41939.1 - 3.5e-05 23.1 1.1 0.12 11.9 0.0 3.9 3 0 0 3 3 3 2 PQQ enzyme repeat Kdo PF06293.9 KFH41939.1 - 0.0011 18.1 0.0 0.0025 16.9 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KFH41939.1 - 0.033 13.5 0.0 0.091 12.0 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL zf-C3HC4_3 PF13920.1 KFH41940.1 - 0.0001 21.9 9.4 0.0001 21.9 6.5 3.0 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) E_raikovi_mat PF06360.6 KFH41940.1 - 3.7 7.8 5.9 0.8 9.9 0.1 2.6 3 0 0 3 3 3 0 Euplotes raikovi mating pheromone Polysacc_lyase PF14099.1 KFH41941.1 - 0.28 10.8 3.1 0.69 9.5 2.2 1.6 1 1 0 1 1 1 0 Polysaccharide lyase DUF604 PF04646.7 KFH41943.1 - 4.9e-12 45.5 0.0 1.2e-09 37.7 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function, DUF604 Fringe PF02434.11 KFH41943.1 - 1.8e-07 30.6 0.0 3.1e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Fringe-like DUF1903 PF08991.5 KFH41945.1 - 0.00057 19.9 2.4 0.0008 19.5 1.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 KFH41945.1 - 0.00089 19.1 4.5 0.0015 18.3 3.1 1.5 1 0 0 1 1 1 1 CHCH domain Pox_A28 PF04584.9 KFH41945.1 - 0.039 13.8 0.0 0.055 13.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A28 family Cmc1 PF08583.5 KFH41945.1 - 1.4 8.7 5.3 1.1 9.1 0.2 2.4 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pectate_lyase_3 PF12708.2 KFH41946.1 - 9.5e-05 22.6 0.0 0.00024 21.2 0.0 1.6 2 0 0 2 2 2 1 Pectate lyase superfamily protein eIF2A PF08662.6 KFH41947.1 - 1.2e-41 142.6 1.3 4.6e-39 134.1 0.1 3.9 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A RRM_5 PF13893.1 KFH41947.1 - 2.2e-05 24.2 0.0 4.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH41947.1 - 0.00042 20.2 0.0 0.00096 19.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 KFH41947.1 - 0.0023 17.7 0.4 1.7 8.6 0.0 3.7 4 0 0 4 4 4 1 WD domain, G-beta repeat RRM_1 PF00076.17 KFH41947.1 - 0.0061 16.1 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3091 PF11291.3 KFH41949.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3091) YscK PF06578.7 KFH41949.1 - 0.15 11.4 2.3 0.27 10.6 1.6 1.4 1 0 0 1 1 1 0 YOP proteins translocation protein K (YscK) Ribonuclease PF00545.15 KFH41950.1 - 1.8e-18 66.3 0.6 3.1e-18 65.6 0.2 1.4 1 1 0 1 1 1 1 ribonuclease Anophelin PF10731.4 KFH41950.1 - 0.34 11.0 1.8 0.61 10.2 1.2 1.3 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito NDUF_B8 PF05821.6 KFH41951.1 - 2.1e-06 27.4 0.1 2.5e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) 2OG-FeII_Oxy_4 PF13661.1 KFH41951.1 - 0.029 13.9 0.7 7.8 6.2 0.3 2.6 2 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KFH41952.1 - 1.7e-10 41.2 0.0 3.2e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KFH41952.1 - 4.4e-05 23.0 0.0 0.00011 21.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KFH41952.1 - 0.031 14.5 0.0 0.07 13.4 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily SWIB PF02201.13 KFH41954.1 - 3e-25 87.7 0.1 6.7e-25 86.5 0.1 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 KFH41954.1 - 4.4e-14 51.9 0.5 9.4e-14 50.9 0.4 1.6 1 0 0 1 1 1 1 DEK C terminal domain Utp11 PF03998.8 KFH41954.1 - 0.075 12.8 4.9 0.11 12.3 3.4 1.2 1 0 0 1 1 1 0 Utp11 protein SRP-alpha_N PF04086.8 KFH41954.1 - 0.55 9.5 9.5 0.7 9.2 6.6 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Corona_nucleoca PF00937.13 KFH41954.1 - 2.1 7.2 10.8 0.7 8.7 5.8 1.3 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein GST_N_3 PF13417.1 KFH41955.1 - 6.5e-14 51.9 0.0 1.2e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KFH41955.1 - 1.9e-12 47.1 0.0 3e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFH41955.1 - 3.4e-12 46.1 0.0 5.5e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFH41955.1 - 3.9e-11 42.7 0.0 5.6e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFH41955.1 - 1.8e-06 27.7 0.0 2.9e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFH41955.1 - 0.0008 19.8 0.0 0.0011 19.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pkinase PF00069.20 KFH41956.1 - 1.1e-67 227.9 0.0 1.7e-67 227.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH41956.1 - 5.8e-40 136.9 0.0 8.5e-40 136.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH41956.1 - 3.1e-11 42.7 0.0 1.4e-09 37.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KFH41956.1 - 3.1e-05 23.8 1.7 0.046 13.4 0.1 3.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 KFH41956.1 - 0.0036 16.4 0.0 0.011 14.7 0.0 1.8 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KFH41956.1 - 0.13 11.0 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.15 KFH41956.1 - 0.63 9.5 2.9 0.71 9.3 0.0 2.4 3 0 0 3 3 3 0 Choline/ethanolamine kinase DUF3445 PF11927.3 KFH41957.1 - 3.4e-56 190.3 0.0 7e-43 146.8 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3445) CcmD PF04995.9 KFH41957.1 - 0.13 11.9 2.9 0.25 11.0 2.0 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) NatB_MDM20 PF09797.4 KFH41958.1 - 1.8e-46 158.5 0.0 2.7e-46 157.9 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_12 PF13424.1 KFH41959.1 - 9.4e-16 57.5 1.1 1.3e-10 41.0 0.5 3.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 KFH41959.1 - 5.2e-08 32.1 1.0 6.4e-05 22.3 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFH41959.1 - 1.5e-07 30.9 1.6 9.9e-06 25.1 0.3 3.2 3 1 1 4 4 4 1 TPR repeat TPR_10 PF13374.1 KFH41959.1 - 2.6e-07 30.3 0.9 0.0003 20.5 0.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat NB-ARC PF00931.17 KFH41959.1 - 6.9e-06 25.1 0.0 0.00041 19.3 0.0 2.5 1 1 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 KFH41959.1 - 0.00021 21.3 0.0 0.00073 19.5 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain TPR_7 PF13176.1 KFH41959.1 - 0.00039 19.9 0.4 0.047 13.5 0.1 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFH41959.1 - 0.00043 19.9 4.5 0.13 12.2 0.1 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat AAA_22 PF13401.1 KFH41959.1 - 0.0025 17.9 0.0 0.017 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain TPR_8 PF13181.1 KFH41959.1 - 0.0033 17.0 9.1 0.076 12.8 0.2 5.0 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFH41959.1 - 0.0077 16.7 1.2 6.8 7.6 0.0 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat Arch_ATPase PF01637.13 KFH41959.1 - 0.019 14.6 0.2 0.059 13.0 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase KaiC PF06745.8 KFH41959.1 - 0.026 13.6 0.0 0.065 12.3 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.1 KFH41959.1 - 0.026 14.4 0.0 0.069 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain TPR_3 PF07720.7 KFH41959.1 - 0.055 13.2 3.0 1.3 8.9 0.0 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFH41959.1 - 0.057 14.1 0.2 0.69 10.6 0.2 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF258 PF03193.11 KFH41959.1 - 0.069 12.3 0.0 0.56 9.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Prenyltrans PF00432.16 KFH41960.1 - 1.5e-36 123.5 11.4 9.2e-08 31.5 0.0 7.0 7 1 0 7 7 7 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KFH41960.1 - 5e-22 78.4 0.1 8.3e-15 55.1 0.0 4.0 2 2 2 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 KFH41960.1 - 1.4e-09 37.9 0.0 3.7e-05 23.7 0.0 2.7 2 1 0 2 2 2 2 Prenyltransferase-like Arylesterase PF01731.15 KFH41962.1 - 0.029 14.3 0.0 0.063 13.2 0.0 1.6 1 0 0 1 1 1 0 Arylesterase Collagen PF01391.13 KFH41963.1 - 6e-05 22.5 7.6 9.9e-05 21.8 5.2 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Prenyltrans_1 PF13243.1 KFH41963.1 - 0.00035 20.5 0.1 1.7 8.6 0.0 3.5 4 0 0 4 4 4 2 Prenyltransferase-like Prenyltrans_2 PF13249.1 KFH41963.1 - 0.0015 18.9 0.7 7.1 7.0 0.1 4.7 2 2 2 5 5 5 2 Prenyltransferase-like Terpene_synth_C PF03936.11 KFH41963.1 - 0.032 13.4 0.2 6.9 5.8 0.0 2.6 2 1 0 2 2 2 0 Terpene synthase family, metal binding domain CHAT PF12770.2 KFH41964.1 - 5.3e-07 29.0 0.2 7.7e-07 28.5 0.1 1.3 1 0 0 1 1 1 1 CHAT domain Mucin PF01456.12 KFH41964.1 - 0.068 12.9 3.3 0.14 11.8 2.3 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Zn_clus PF00172.13 KFH41965.1 - 0.00093 19.0 12.0 0.00093 19.0 8.3 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF605 PF04652.11 KFH41965.1 - 9.1 5.5 11.8 17 4.6 8.2 1.4 1 0 0 1 1 1 0 Vta1 like FBPase PF00316.15 KFH41966.1 - 1.2e-48 165.6 0.0 1.6e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase polyprenyl_synt PF00348.12 KFH41967.1 - 2.2e-49 167.6 0.0 2.9e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Cortexin PF11057.3 KFH41967.1 - 0.079 12.5 0.1 0.36 10.4 0.0 2.1 2 0 0 2 2 2 0 Cortexin of kidney DUF336 PF03928.9 KFH41968.1 - 2.2e-16 59.8 0.0 2.8e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF336) TAT_signal PF10518.4 KFH41968.1 - 0.11 12.6 0.7 11 6.2 0.1 2.6 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence Zn_clus PF00172.13 KFH41970.1 - 6.8e-08 32.3 23.2 0.00011 22.0 2.2 3.1 3 0 0 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_pol3_gamma3 PF12169.3 KFH41970.1 - 0.17 11.6 0.9 0.27 11.0 0.1 1.7 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III GST_N_3 PF13417.1 KFH41971.1 - 3.2e-14 52.8 0.0 5.7e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KFH41971.1 - 1.1e-12 47.9 0.0 2.4e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFH41971.1 - 3.2e-11 43.0 0.0 6.2e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFH41971.1 - 3.5e-09 36.5 0.0 8e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFH41971.1 - 6.6e-09 35.5 0.1 1.9e-08 34.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFH41971.1 - 6.9e-08 32.8 0.1 1.6e-07 31.6 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ribosomal_L37 PF08561.5 KFH41971.1 - 4.8 6.8 5.8 4.5 6.9 1.4 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L37 Med11 PF10280.4 KFH41973.1 - 6.5e-27 93.9 0.0 8e-27 93.6 0.0 1.1 1 0 0 1 1 1 1 Mediator complex protein Vps5 PF09325.5 KFH41974.1 - 1.9e-86 289.1 3.2 2.7e-86 288.6 2.2 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 KFH41974.1 - 4.2e-24 84.5 0.0 9.5e-24 83.3 0.0 1.6 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.4 KFH41974.1 - 0.0023 17.2 0.8 0.0098 15.1 0.5 1.9 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein BAR PF03114.13 KFH41974.1 - 0.0043 16.5 3.3 0.0069 15.9 2.3 1.3 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 KFH41974.1 - 0.012 14.5 1.3 0.02 13.8 0.9 1.3 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking His_Phos_2 PF00328.17 KFH41974.1 - 0.016 14.5 1.2 0.016 14.5 0.8 1.5 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) Ytp1 PF10355.4 KFH41975.1 - 3.9e-81 272.2 17.1 3.9e-81 272.2 11.9 1.7 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KFH41975.1 - 9.7e-23 79.7 3.7 9.2e-15 54.1 0.6 4.3 5 0 0 5 5 5 2 Domain of unknown function (DUF2427) Ketoacyl-synt_C PF02801.17 KFH41975.1 - 0.054 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain Pho86 PF11124.3 KFH41975.1 - 0.23 10.4 1.4 0.34 9.8 0.0 1.8 2 0 0 2 2 2 0 Inorganic phosphate transporter Pho86 Flavin_Reduct PF01613.13 KFH41976.1 - 5.8e-33 113.9 0.0 7.2e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Fungal_trans PF04082.13 KFH41977.1 - 1e-10 40.9 0.0 2.5e-10 39.6 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Trypan_glycop_C PF10659.4 KFH41977.1 - 0.1 12.8 0.8 0.23 11.7 0.6 1.5 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain WD40 PF00400.27 KFH41978.1 - 9.9e-72 234.4 15.3 5e-12 45.2 0.1 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KFH41978.1 - 2.2e-08 32.7 3.5 0.00024 19.4 0.0 4.4 2 2 1 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFH41978.1 - 0.0035 16.1 0.0 0.59 8.8 0.0 2.4 1 1 1 2 2 2 2 Nup133 N terminal like Hira PF07569.6 KFH41978.1 - 0.11 11.6 0.1 4.5 6.4 0.0 2.4 2 0 0 2 2 2 0 TUP1-like enhancer of split Zn_clus PF00172.13 KFH41979.1 - 3e-08 33.4 12.4 5.2e-08 32.6 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 KFH41979.1 - 0.56 10.3 8.9 1.1 9.4 6.2 1.4 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region MBOAT PF03062.14 KFH41980.1 - 1.3e-29 103.3 15.3 1.1e-28 100.2 10.6 2.1 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF488 PF04343.8 KFH41981.1 - 1e-25 90.4 0.5 1.1e-25 90.3 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF488 DinB_2 PF12867.2 KFH41981.1 - 0.041 14.2 0.5 0.056 13.7 0.4 1.2 1 0 0 1 1 1 0 DinB superfamily TPR_14 PF13428.1 KFH41981.1 - 0.08 13.6 0.3 0.29 11.8 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3848 PF12959.2 KFH41981.1 - 0.1 12.5 0.5 0.21 11.5 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3848) DnaJ PF00226.26 KFH41982.1 - 2.3e-21 75.3 3.0 2.3e-21 75.3 2.1 2.6 2 1 0 2 2 2 1 DnaJ domain p450 PF00067.17 KFH41983.1 - 4.7e-37 127.5 0.0 5.3e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KFH41984.1 - 3.4e-51 174.1 0.0 3.9e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FlbD PF06289.6 KFH41984.1 - 0.1 11.9 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Flagellar protein (FlbD) 3HCDH_N PF02737.13 KFH41985.1 - 2.3e-33 115.3 0.0 5.5e-33 114.1 0.0 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KFH41985.1 - 1.5e-09 38.1 0.1 3.8e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain UDPG_MGDP_dh_N PF03721.9 KFH41985.1 - 0.032 13.6 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.16 KFH41985.1 - 0.068 12.9 0.1 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 ThiF family 2-Hacid_dh_C PF02826.14 KFH41985.1 - 0.091 11.8 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RIIa PF02197.12 KFH41985.1 - 0.12 11.8 0.1 0.33 10.4 0.0 1.7 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit Aldedh PF00171.17 KFH41986.1 - 1.1e-137 459.1 0.2 1.2e-137 459.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family UIM PF02809.15 KFH41986.1 - 0.046 13.2 0.6 1.1 8.9 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin interaction motif MFS_1 PF07690.11 KFH41987.1 - 1.7e-41 142.1 45.2 5e-41 140.5 31.3 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH41987.1 - 8.2e-14 51.0 27.0 2.1e-12 46.4 10.6 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 KFH41987.1 - 2.3e-10 39.3 14.8 2.9e-10 38.9 10.0 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PSDC PF12588.3 KFH41988.1 - 5e-50 168.7 0.0 7.1e-50 168.2 0.0 1.2 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 KFH41988.1 - 3.4e-33 114.6 0.0 4.5e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.1 KFH41988.1 - 0.031 13.9 0.1 0.7 9.6 0.1 2.3 2 0 0 2 2 2 0 Biotin-lipoyl like Pup_ligase PF03136.10 KFH41988.1 - 0.1 11.2 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Pup-ligase protein Metallophos PF00149.23 KFH41989.1 - 8.9e-06 25.2 1.0 0.0032 16.8 0.0 2.7 3 1 0 3 3 3 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KFH41989.1 - 0.0015 18.4 0.1 0.017 15.0 0.1 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 KFH41989.1 - 0.15 11.1 0.0 0.32 10.0 0.0 1.4 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily WD40 PF00400.27 KFH41991.1 - 1e-44 148.8 20.3 5.7e-08 32.3 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 KFH41991.1 - 1.8e-37 128.5 0.1 6.8e-31 107.2 0.0 2.2 2 0 0 2 2 2 2 WD40 associated region in TFIID subunit LisH PF08513.6 KFH41991.1 - 4.2e-09 35.8 0.2 8.1e-07 28.5 0.0 2.5 2 0 0 2 2 2 2 LisH eIF2A PF08662.6 KFH41991.1 - 0.00032 20.4 0.0 0.009 15.7 0.0 2.9 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 KFH41991.1 - 0.01 14.6 0.1 1 8.0 0.0 3.4 3 1 0 3 3 3 0 Nup133 N terminal like MFS_1 PF07690.11 KFH41992.1 - 3.7e-43 147.5 33.9 3.7e-43 147.5 23.5 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH41992.1 - 4e-07 28.9 13.4 4e-07 28.9 9.3 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter EPTP PF03736.12 KFH41994.1 - 1.9e-23 81.9 9.1 2.8e-05 23.7 0.0 7.6 7 1 0 7 7 7 5 EPTP domain GMC_oxred_C PF05199.8 KFH41995.1 - 4.3e-30 104.8 0.0 7e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KFH41995.1 - 5.7e-29 101.2 0.0 1.7e-27 96.3 0.0 2.5 1 1 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KFH41995.1 - 7.1e-05 21.8 0.1 0.003 16.5 0.0 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFH41995.1 - 8.2e-05 22.5 0.0 0.00027 20.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFH41995.1 - 9.8e-05 21.3 0.0 0.0031 16.4 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KFH41995.1 - 0.00039 20.3 0.4 0.00093 19.1 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KFH41995.1 - 0.0035 16.4 0.0 0.0059 15.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 KFH41995.1 - 0.0059 15.5 0.0 0.0089 14.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KFH41995.1 - 0.01 15.9 0.0 0.51 10.3 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFH41995.1 - 0.052 12.0 0.1 0.078 11.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.11 KFH41995.1 - 0.082 12.3 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF1883 PF08980.5 KFH41995.1 - 0.093 12.2 0.0 0.33 10.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1883) Rossmann-like PF10727.4 KFH41995.1 - 0.095 12.4 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Rossmann-like domain Pyr_redox PF00070.22 KFH41995.1 - 0.15 12.4 0.3 0.38 11.1 0.1 1.7 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 KFH41995.1 - 0.18 11.4 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HSP90 PF00183.13 KFH41996.1 - 1.8e-126 422.6 21.1 1.6e-111 373.3 4.0 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.1 KFH41996.1 - 4.9e-12 45.6 0.3 1.5e-11 44.0 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KFH41996.1 - 2.5e-11 43.2 0.0 4.7e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1676 PF07898.8 KFH41996.1 - 0.015 15.5 0.3 0.015 15.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) FTA4 PF13093.1 KFH41996.1 - 0.037 13.4 1.7 0.07 12.5 1.2 1.4 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Peptidase_S10 PF00450.17 KFH41996.1 - 0.052 12.7 0.2 0.11 11.6 0.0 1.5 2 0 0 2 2 2 0 Serine carboxypeptidase Methyltransf_16 PF10294.4 KFH41998.1 - 3.1e-19 69.0 0.0 6.8e-19 67.9 0.0 1.4 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_18 PF12847.2 KFH41998.1 - 1e-06 29.2 0.0 1.9e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFH41998.1 - 9e-05 21.9 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.11 KFH41998.1 - 0.00016 21.3 0.0 0.00025 20.6 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.8 KFH41998.1 - 0.0014 17.8 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 KFH41998.1 - 0.0026 17.5 0.0 0.004 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH41998.1 - 0.0074 15.8 0.0 0.022 14.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 KFH41998.1 - 0.0082 15.7 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.7 KFH41998.1 - 0.015 14.8 0.0 0.11 11.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Methyltransf_26 PF13659.1 KFH41998.1 - 0.028 14.4 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KFH41998.1 - 0.03 14.8 0.0 0.058 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 KFH41998.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.12 KFH41998.1 - 0.19 10.7 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Glutaredoxin PF00462.19 KFH42000.1 - 1.8e-16 59.8 0.0 2.9e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DAO PF01266.19 KFH42002.1 - 6.4e-21 74.6 0.2 1.2e-20 73.7 0.1 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFH42002.1 - 0.00021 21.6 1.6 0.00069 19.9 1.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFH42002.1 - 0.00048 20.2 0.0 0.0008 19.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFH42002.1 - 0.0009 19.2 0.1 0.0027 17.6 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KFH42002.1 - 0.0019 17.3 0.8 0.0089 15.1 0.1 2.0 2 0 0 2 2 2 1 Thi4 family 3HCDH_N PF02737.13 KFH42002.1 - 0.028 14.0 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 KFH42002.1 - 0.049 13.4 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFH42002.1 - 0.082 12.6 0.1 0.16 11.7 0.1 1.6 1 1 0 1 1 1 0 FAD-NAD(P)-binding Ldh_1_N PF00056.18 KFH42002.1 - 0.1 12.4 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ThiF PF00899.16 KFH42002.1 - 0.1 12.4 0.5 0.1 12.4 0.3 1.8 2 0 0 2 2 2 0 ThiF family UDPG_MGDP_dh_N PF03721.9 KFH42002.1 - 0.25 10.6 0.8 0.45 9.8 0.5 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pro_isomerase PF00160.16 KFH42003.1 - 1.1e-34 119.8 0.0 1.7e-34 119.2 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 KFH42003.1 - 3.2e-15 55.5 0.0 5.6e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH42003.1 - 1.2e-10 41.1 0.0 2.6e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH42003.1 - 1.8e-08 34.0 0.3 4.4e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G_glu_transpept PF01019.16 KFH42004.1 - 6.2e-166 552.8 0.0 7.1e-166 552.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Aminotran_4 PF01063.14 KFH42005.1 - 2.7e-25 89.2 0.0 3.6e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV PMI_typeI PF01238.16 KFH42006.1 - 1.3e-132 442.2 0.0 1.5e-132 442.0 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I zf-SAP30 PF13866.1 KFH42008.1 - 0.076 12.6 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 SAP30 zinc-finger DinI PF06183.8 KFH42008.1 - 0.098 12.6 0.7 0.24 11.4 0.5 1.7 1 0 0 1 1 1 0 DinI-like family Fic PF02661.13 KFH42009.1 - 6.1e-08 33.2 0.2 1.2e-07 32.3 0.1 1.5 1 0 0 1 1 1 1 Fic/DOC family Ribosomal_S24e PF01282.14 KFH42010.1 - 9e-35 118.3 0.0 1.4e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Sugar_tr PF00083.19 KFH42011.1 - 1.1e-88 297.8 10.7 1.5e-88 297.3 7.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH42011.1 - 7.2e-27 94.0 27.4 5.8e-26 91.0 15.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFH42011.1 - 4.1e-08 31.9 3.0 4.1e-08 31.9 2.0 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Actin PF00022.14 KFH42012.1 - 4.7e-118 394.0 0.0 5.3e-118 393.8 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KFH42012.1 - 0.012 14.2 0.0 0.14 10.6 0.0 2.4 1 1 0 1 1 1 0 MreB/Mbl protein Arf PF00025.16 KFH42013.1 - 2.4e-75 251.6 0.2 2.7e-75 251.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFH42013.1 - 5e-13 48.7 0.0 5.8e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KFH42013.1 - 4.7e-12 45.2 2.3 9e-09 34.4 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 KFH42013.1 - 3.1e-11 42.8 0.0 3.9e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KFH42013.1 - 5.3e-11 42.1 0.0 6.5e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KFH42013.1 - 1.9e-07 31.5 0.0 2.8e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KFH42013.1 - 0.0017 18.2 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 KFH42013.1 - 0.034 13.2 0.2 0.066 12.2 0.0 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase CRISPR_Cas2 PF09827.4 KFH42013.1 - 0.054 13.6 0.0 0.094 12.8 0.0 1.4 1 0 0 1 1 1 0 CRISPR associated protein Cas2 GTP_cyclohydro2 PF00925.15 KFH42014.1 - 3.6e-59 198.7 0.0 8.1e-55 184.6 0.0 2.1 1 1 1 2 2 2 2 GTP cyclohydrolase II DUF4419 PF14388.1 KFH42015.1 - 1e-33 116.8 0.1 1.1e-33 116.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) COG2 PF06148.6 KFH42017.1 - 0.0058 16.5 3.7 0.43 10.4 0.1 2.2 1 1 1 2 2 2 2 COG (conserved oligomeric Golgi) complex component, COG2 RdRP_4 PF02123.11 KFH42017.1 - 0.029 13.1 0.6 0.034 12.8 0.4 1.1 1 0 0 1 1 1 0 Viral RNA-directed RNA-polymerase FlxA PF14282.1 KFH42017.1 - 0.077 12.9 0.8 0.18 11.7 0.6 1.6 1 0 0 1 1 1 0 FlxA-like protein Sugarporin_N PF11471.3 KFH42017.1 - 0.18 11.4 0.1 0.18 11.4 0.1 2.1 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Transpep_BrtH PF14399.1 KFH42017.1 - 2 7.5 5.8 0.23 10.7 0.9 1.7 2 0 0 2 2 2 0 NlpC/p60-like transpeptidase HSCB_C PF07743.8 KFH42017.1 - 3 8.3 9.8 11 6.6 1.1 2.5 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain G_glu_transpept PF01019.16 KFH42018.1 - 2.2e-139 465.2 0.0 2.5e-139 465.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase RF-1 PF00472.15 KFH42020.1 - 4.7e-34 116.5 1.8 4.7e-34 116.5 1.2 1.8 2 0 0 2 2 2 1 RF-1 domain PCRF PF03462.13 KFH42020.1 - 1.6e-21 76.1 0.0 3.5e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 PCRF domain CTP_transf_2 PF01467.21 KFH42021.1 - 1.1e-13 51.4 0.0 4.4e-10 39.8 0.0 3.4 2 1 0 2 2 2 2 Cytidylyltransferase Zn_clus PF00172.13 KFH42022.1 - 2.1e-08 33.8 7.5 2.1e-08 33.8 5.2 1.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Elong-fact-P_C PF09285.6 KFH42024.1 - 0.12 11.7 0.0 0.5 9.7 0.0 1.9 2 0 0 2 2 2 0 Elongation factor P, C-terminal Bac_globin PF01152.16 KFH42025.1 - 0.096 12.7 0.0 0.85 9.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial-like globin GST_N_2 PF13409.1 KFH42026.1 - 4.2e-13 49.0 0.0 6.4e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KFH42026.1 - 1e-11 44.8 0.0 2.9e-11 43.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KFH42026.1 - 4.7e-08 33.0 0.0 9.5e-08 32.1 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFH42026.1 - 2e-07 30.8 0.2 3.1e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFH42026.1 - 0.0032 17.4 0.0 0.0058 16.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Asp_Glu_race PF01177.17 KFH42027.1 - 2.3e-17 63.6 0.0 2.7e-17 63.3 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Pkinase PF00069.20 KFH42028.1 - 1.6e-55 188.0 0.0 9.9e-55 185.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH42028.1 - 1e-26 93.6 0.0 3.1e-26 92.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Zip PF02535.17 KFH42028.1 - 0.00025 20.1 0.2 0.00033 19.7 0.2 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Macoilin PF09726.4 KFH42028.1 - 0.59 8.3 3.2 0.87 7.7 2.2 1.2 1 0 0 1 1 1 0 Transmembrane protein Innate_immun PF12782.2 KFH42028.1 - 1.1 8.4 9.5 2 7.5 6.6 1.3 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family DUF755 PF05501.6 KFH42028.1 - 1.9 8.5 13.7 3.7 7.6 8.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF755) DUF1325 PF07039.6 KFH42029.1 - 5.6e-30 103.6 0.0 8.5e-30 103.0 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain MutL PF13941.1 KFH42029.1 - 0.021 13.1 0.1 0.033 12.5 0.0 1.2 1 0 0 1 1 1 0 MutL protein Cerato-platanin PF07249.7 KFH42030.1 - 0.00011 22.1 0.0 0.00021 21.3 0.0 1.4 1 0 0 1 1 1 1 Cerato-platanin cwf21 PF08312.7 KFH42031.1 - 2e-17 62.7 12.5 2e-17 62.7 8.6 2.0 2 0 0 2 2 2 1 cwf21 domain DUF1129 PF06570.6 KFH42031.1 - 0.14 11.4 0.3 0.19 11.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Trans_reg_C PF00486.23 KFH42031.1 - 0.27 11.1 1.4 0.67 9.9 0.0 2.3 2 1 1 3 3 3 0 Transcriptional regulatory protein, C terminal GvpG PF05120.7 KFH42031.1 - 2.3 8.1 9.4 7.8 6.3 1.1 2.4 2 1 0 2 2 2 0 Gas vesicle protein G RhoGAP PF00620.22 KFH42032.1 - 2.7e-36 124.4 0.0 4.4e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain DUF290 PF01060.18 KFH42032.1 - 0.18 11.8 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 Transthyretin-like family Nup188 PF10487.4 KFH42033.1 - 9.7e-25 86.6 2.9 8.7e-24 83.5 0.7 2.2 2 0 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 Abhydrolase_6 PF12697.2 KFH42034.1 - 3e-22 79.6 0.0 3.5e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFH42034.1 - 6.4e-16 58.5 0.0 9.2e-15 54.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFH42034.1 - 3.5e-07 30.0 0.0 9.8e-07 28.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 KFH42034.1 - 5.6e-05 21.7 0.0 0.00016 20.2 0.0 1.9 1 1 0 1 1 1 1 Ndr family Aminotran_3 PF00202.16 KFH42035.1 - 2.7e-108 361.8 0.0 3.4e-108 361.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 KFH42035.1 - 4.8e-06 25.9 0.0 7.8e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KFH42035.1 - 0.049 12.5 0.0 0.066 12.1 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II HeLo PF14479.1 KFH42036.1 - 4.4e-13 49.4 0.0 7.3e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation SH3_1 PF00018.23 KFH42037.1 - 1.8e-15 56.0 0.1 2.8e-15 55.4 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFH42037.1 - 5.2e-11 41.9 0.1 7.8e-11 41.3 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFH42037.1 - 9.9e-10 37.7 0.1 1.5e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain zf-CCCH PF00642.19 KFH42038.1 - 3.4e-05 23.3 0.1 5.7e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 KFH42038.1 - 0.24 10.8 2.0 0.43 10.1 1.4 1.4 1 0 0 1 1 1 0 Putative zinc-finger domain Allexi_40kDa PF05549.6 KFH42038.1 - 0.9 8.7 7.5 0.25 10.6 1.0 2.7 1 1 1 2 2 2 0 Allexivirus 40kDa protein Seryl_tRNA_N PF02403.17 KFH42038.1 - 1.1 9.3 12.1 0.52 10.3 2.9 3.2 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Spc24 PF08286.6 KFH42038.1 - 7.8 6.2 8.0 22 4.7 1.9 3.3 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 DivIC PF04977.10 KFH42038.1 - 8.9 5.8 12.9 3 7.4 0.0 2.8 3 0 0 3 3 3 0 Septum formation initiator RRM_1 PF00076.17 KFH42039.1 - 2.8e-09 36.4 0.0 1e-08 34.6 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH42039.1 - 1.6e-08 34.4 0.0 3.7e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 KFH42040.1 - 2.7e-27 95.5 0.0 3e-24 85.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Ank_2 PF12796.2 KFH42040.1 - 1.8e-21 76.2 3.7 5.9e-08 32.9 0.0 5.0 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Pkinase_Tyr PF07714.12 KFH42040.1 - 1.8e-19 69.8 0.0 1.6e-18 66.6 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Ank_4 PF13637.1 KFH42040.1 - 3e-16 59.4 0.8 0.001 19.5 0.0 5.6 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 KFH42040.1 - 1.7e-10 40.1 9.8 0.0013 18.3 0.0 7.1 8 0 0 8 8 8 2 Ankyrin repeat Ank_5 PF13857.1 KFH42040.1 - 6.8e-10 38.8 6.5 0.0011 19.1 0.0 6.0 3 1 2 5 5 5 3 Ankyrin repeats (many copies) APH PF01636.18 KFH42040.1 - 4.2e-07 29.9 13.7 0.011 15.4 0.1 5.0 3 3 2 5 5 5 2 Phosphotransferase enzyme family Kdo PF06293.9 KFH42040.1 - 1.9e-06 27.0 0.3 0.00068 18.7 0.0 3.0 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_3 PF13606.1 KFH42040.1 - 5.6e-05 22.9 6.2 1.8 9.0 0.0 6.6 7 0 0 7 7 6 1 Ankyrin repeat RIO1 PF01163.17 KFH42040.1 - 0.0048 16.2 0.0 1.1 8.5 0.0 2.4 2 0 0 2 2 2 1 RIO1 family Sel1 PF08238.7 KFH42040.1 - 0.021 15.4 1.4 0.041 14.5 0.0 2.4 2 0 0 2 2 1 0 Sel1 repeat DUF2895 PF11444.3 KFH42040.1 - 0.034 13.3 0.0 0.076 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2895) Choline_kinase PF01633.15 KFH42040.1 - 0.075 12.5 0.0 16 5.0 0.0 2.5 1 1 1 2 2 2 0 Choline/ethanolamine kinase F-box PF00646.28 KFH42040.1 - 0.12 12.0 0.6 1.2 8.8 0.3 2.5 2 0 0 2 2 2 0 F-box domain Pox_ser-thr_kin PF05445.6 KFH42040.1 - 1.2 7.8 0.0 2.1 7.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Sod_Cu PF00080.15 KFH42041.1 - 8.8e-45 152.3 3.3 1e-44 152.1 2.3 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) MOSC_N PF03476.11 KFH42042.1 - 1.4e-12 47.3 0.0 2.6e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 KFH42042.1 - 2.3e-12 46.5 0.0 9.3e-12 44.5 0.0 1.9 1 1 0 1 1 1 1 MOSC domain DUF3716 PF12511.3 KFH42043.1 - 1.6e-16 59.6 7.1 2.7e-16 58.9 4.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Packaging_FI PF14000.1 KFH42043.1 - 0.057 13.6 1.5 0.095 12.9 1.1 1.3 1 0 0 1 1 1 0 DNA packaging protein FI Transaldolase PF00923.14 KFH42044.1 - 1e-93 313.6 1.2 1.2e-93 313.3 0.8 1.0 1 0 0 1 1 1 1 Transaldolase TALPID3 PF15324.1 KFH42044.1 - 0.08 10.2 0.0 0.1 9.9 0.0 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Pet191_N PF10203.4 KFH42045.1 - 2.3e-28 97.9 4.0 2.8e-28 97.7 2.8 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 PAN_3 PF08277.7 KFH42045.1 - 0.061 12.9 0.4 0.097 12.3 0.3 1.3 1 0 0 1 1 1 0 PAN-like domain Cmc1 PF08583.5 KFH42045.1 - 0.2 11.4 4.6 1.7 8.4 0.5 2.3 1 1 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Clusterin PF01093.12 KFH42045.1 - 0.31 9.7 1.8 0.34 9.6 1.3 1.0 1 0 0 1 1 1 0 Clusterin Macin PF14865.1 KFH42045.1 - 1.5 8.9 4.4 13 5.9 0.7 2.1 2 0 0 2 2 2 0 Macin IGPS PF00218.16 KFH42046.1 - 4.1e-94 314.3 0.2 7.1e-94 313.6 0.1 1.4 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.23 KFH42046.1 - 8.7e-49 165.5 0.0 2.6e-48 164.0 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase class-I PRAI PF00697.17 KFH42046.1 - 1.5e-47 161.7 0.0 4.1e-44 150.5 0.0 2.6 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.8 KFH42046.1 - 3.9e-06 26.4 0.0 1.9e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 Peptidase C26 QRPTase_C PF01729.14 KFH42046.1 - 0.0013 18.2 1.0 0.21 11.1 0.1 3.0 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain HIF-1a_CTAD PF08778.5 KFH42046.1 - 0.013 14.9 0.0 0.076 12.4 0.0 2.1 2 0 0 2 2 2 0 HIF-1 alpha C terminal transactivation domain FMN_dh PF01070.13 KFH42046.1 - 0.017 13.9 0.3 0.069 11.9 0.0 1.9 2 0 0 2 2 2 0 FMN-dependent dehydrogenase His_biosynth PF00977.16 KFH42046.1 - 0.069 12.4 0.0 0.2 10.8 0.0 1.8 1 0 0 1 1 1 0 Histidine biosynthesis protein Use1 PF09753.4 KFH42047.1 - 1.4e-05 24.6 0.0 2.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Membrane fusion protein Use1 MCPVI PF02993.9 KFH42047.1 - 2.5 8.2 10.8 0.6 10.2 4.5 1.8 1 1 1 2 2 2 0 Minor capsid protein VI Glyco_transf_22 PF03901.12 KFH42048.1 - 2.6e-76 257.3 16.2 3.3e-76 256.9 11.2 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family zf-Tim10_DDP PF02953.10 KFH42049.1 - 1.3e-19 69.2 1.2 1.3e-19 69.2 0.9 1.6 1 1 1 2 2 2 2 Tim10/DDP family zinc finger DUF842 PF05811.8 KFH42049.1 - 0.016 14.6 5.1 0.09 12.2 3.5 1.9 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) KxDL PF10241.4 KFH42049.1 - 0.034 14.0 3.5 1.7 8.6 0.6 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein G-alpha PF00503.15 KFH42050.1 - 1.9e-134 448.2 2.1 2.3e-134 447.9 1.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFH42050.1 - 3.1e-15 55.8 2.0 2.3e-10 39.9 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 KFH42050.1 - 9.5e-05 21.8 0.0 0.00041 19.8 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 KFH42050.1 - 0.0015 18.9 0.6 2.7 8.5 0.1 2.8 2 2 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 KFH42050.1 - 0.0057 15.8 2.9 0.27 10.3 0.0 2.6 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 KFH42050.1 - 0.0099 15.3 0.0 0.022 14.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 KFH42050.1 - 0.03 13.7 0.0 1.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MCM PF00493.18 KFH42050.1 - 0.085 11.6 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family MMR_HSR1 PF01926.18 KFH42050.1 - 0.11 12.4 0.0 16 5.4 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 KFH42050.1 - 0.12 11.8 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MmgE_PrpD PF03972.9 KFH42051.1 - 4.5e-150 499.7 0.0 5.2e-150 499.4 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family CMS1 PF14617.1 KFH42052.1 - 8.7e-87 290.3 1.5 9.6e-87 290.2 1.1 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 KFH42052.1 - 6.1e-07 29.0 0.0 6.5e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase Abhydrolase_1 PF00561.15 KFH42053.1 - 2.3e-21 76.4 0.3 4e-21 75.6 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 KFH42053.1 - 3e-21 74.5 0.0 5.6e-21 73.6 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 KFH42053.1 - 6.2e-09 36.0 0.1 1.9e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH42053.1 - 1.3e-05 24.9 0.0 6.9e-05 22.6 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 KFH42053.1 - 0.00039 19.9 0.0 0.1 12.0 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 KFH42053.1 - 0.064 12.6 0.0 2.6 7.4 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Ras PF00071.17 KFH42054.1 - 1.2e-53 180.7 0.0 1.4e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFH42054.1 - 1.4e-16 61.0 0.0 2.1e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFH42054.1 - 1.1e-05 24.7 0.0 1.4e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Corona_nucleoca PF00937.13 KFH42054.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Myosin_head PF00063.16 KFH42055.1 - 6.4e-247 821.0 1.7 3.6e-246 818.5 0.0 2.6 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 KFH42055.1 - 7.5e-20 70.3 143.9 7.2e-12 43.8 54.4 7.9 2 2 3 6 6 6 6 Myosin tail Myosin_N PF02736.14 KFH42055.1 - 4.8e-06 26.1 1.6 1.3e-05 24.7 1.1 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Filament PF00038.16 KFH42055.1 - 0.00063 19.3 18.0 0.00063 19.3 12.5 10.6 1 1 9 10 10 10 3 Intermediate filament protein AAA_19 PF13245.1 KFH42055.1 - 0.053 13.2 0.0 0.16 11.7 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 KFH42055.1 - 0.16 12.0 0.0 0.16 12.0 0.0 4.3 3 0 0 3 3 3 0 AAA domain SNase PF00565.12 KFH42056.1 - 3.4e-68 226.7 0.3 3e-19 69.2 0.0 5.5 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 KFH42056.1 - 3.2e-25 88.3 0.0 6.5e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 Tudor domain SMN PF06003.7 KFH42056.1 - 4.1e-05 22.8 0.0 9.8e-05 21.5 0.0 1.6 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) D123 PF07065.9 KFH42057.1 - 4.1e-86 288.7 0.0 1.1e-85 287.2 0.0 1.6 1 1 0 1 1 1 1 D123 CDC45 PF02724.9 KFH42057.1 - 0.02 12.9 0.2 0.031 12.3 0.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 KFH42057.1 - 8.8 5.8 8.8 2 8.0 1.8 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Metallophos PF00149.23 KFH42058.1 - 1.8e-08 34.0 0.5 3.7e-08 33.0 0.3 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KFH42058.1 - 2e-08 34.2 0.1 4.3e-08 33.1 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain BRCT PF00533.21 KFH42059.1 - 0.0053 16.8 0.0 0.0098 16.0 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Glyco_hydro_11 PF00457.12 KFH42060.1 - 7.2e-74 247.1 17.8 8.3e-74 246.8 12.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 F1F0-ATPsyn_F PF10791.4 KFH42061.1 - 1.7e-41 140.3 0.5 1.9e-41 140.1 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 KFH42061.1 - 0.0073 16.3 0.2 0.0094 15.9 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f PAP_assoc PF03828.14 KFH42062.1 - 1.8e-16 59.8 0.0 9e-16 57.5 0.0 2.1 1 1 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KFH42062.1 - 0.0013 19.0 0.0 0.0036 17.5 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain HNH_2 PF13391.1 KFH42063.1 - 2.1e-09 37.0 0.1 5.5e-09 35.6 0.1 1.8 1 0 0 1 1 1 1 HNH endonuclease zf-C3HC4 PF00097.20 KFH42064.1 - 1.3e-08 34.3 10.2 1.3e-08 34.3 7.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFH42064.1 - 3e-08 33.2 9.0 3e-08 33.2 6.2 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFH42064.1 - 9.3e-08 31.6 10.2 4e-07 29.5 5.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFH42064.1 - 2.7e-07 30.3 9.5 2.7e-07 30.3 6.6 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFH42064.1 - 6.3e-07 29.3 10.1 6.3e-07 29.3 7.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KFH42064.1 - 3.1e-05 23.6 3.3 6.2e-05 22.6 2.3 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 KFH42064.1 - 3.4e-05 23.6 14.1 4.2e-05 23.3 6.8 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KFH42064.1 - 0.0003 20.8 3.4 0.0003 20.8 2.3 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger SAP PF02037.22 KFH42064.1 - 0.00045 19.6 0.1 0.00085 18.7 0.0 1.5 1 0 0 1 1 1 1 SAP domain zf-RING_UBOX PF13445.1 KFH42064.1 - 0.00065 19.3 6.0 0.0018 17.9 4.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Mob_synth_C PF06463.8 KFH42064.1 - 0.00075 19.1 0.9 0.0019 17.8 0.6 1.6 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C zf-RING_4 PF14570.1 KFH42064.1 - 0.01 15.4 2.8 0.01 15.4 1.9 2.8 2 1 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-C2HC_2 PF13913.1 KFH42064.1 - 0.028 14.0 0.5 0.028 14.0 0.3 2.1 2 0 0 2 2 2 0 zinc-finger of a C2HC-type U-box PF04564.10 KFH42064.1 - 0.03 14.2 0.0 0.069 13.1 0.0 1.6 1 0 0 1 1 1 0 U-box domain zf-P11 PF03854.9 KFH42064.1 - 0.18 11.2 6.2 0.46 9.9 4.3 1.7 1 0 0 1 1 1 0 P-11 zinc finger zf-Apc11 PF12861.2 KFH42064.1 - 0.4 10.5 5.2 0.2 11.4 1.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Fer4_11 PF13247.1 KFH42064.1 - 3.2 7.6 8.1 2.3 8.1 0.1 2.7 2 1 0 2 2 2 0 4Fe-4S dicluster domain MOZ_SAS PF01853.13 KFH42065.1 - 9.7e-84 279.3 0.1 1.3e-83 278.8 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 KFH42065.1 - 9.9e-18 63.6 0.0 2.5e-17 62.2 0.0 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 KFH42065.1 - 0.11 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family MFS_1 PF07690.11 KFH42066.1 - 7.4e-10 38.0 37.3 9.6e-07 27.8 5.8 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ecm33 PF12454.3 KFH42067.1 - 0.019 14.8 0.6 0.019 14.8 0.4 1.9 2 1 0 2 2 2 0 GPI-anchored cell wall organization protein Aminotran_1_2 PF00155.16 KFH42070.1 - 2.2e-23 82.8 0.0 3.1e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Glyco_hydro_10 PF00331.15 KFH42071.1 - 7e-105 350.5 0.6 8e-105 350.3 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 KFH42071.1 - 1.8e-09 37.1 7.3 1.8e-09 37.1 5.1 1.9 2 0 0 2 2 2 1 Fungal cellulose binding domain DUF4339 PF14237.1 KFH42071.1 - 0.026 14.0 0.1 0.061 12.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4339) Glyco_hydro_42 PF02449.10 KFH42071.1 - 0.1 11.7 0.3 0.51 9.3 0.1 1.9 1 1 1 2 2 2 0 Beta-galactosidase Ras PF00071.17 KFH42072.1 - 8.1e-60 200.8 0.4 1.1e-59 200.4 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFH42072.1 - 1.3e-21 77.2 0.1 2.4e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFH42072.1 - 1.5e-18 66.6 0.3 1.8e-18 66.3 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFH42072.1 - 3.6e-08 33.0 0.1 1.6e-07 30.9 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFH42072.1 - 1.6e-06 27.4 0.3 2.1e-06 27.0 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFH42072.1 - 6.9e-06 26.0 0.0 1.1e-05 25.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KFH42072.1 - 7.9e-06 25.2 0.1 1.2e-05 24.6 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 KFH42072.1 - 0.0078 15.7 0.1 0.029 13.9 0.0 1.7 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_28 PF13521.1 KFH42072.1 - 0.02 14.8 0.0 6.6 6.6 0.0 2.2 1 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 KFH42072.1 - 0.026 14.3 0.2 2.9 7.6 0.0 2.5 2 1 0 2 2 2 0 Dynamin family AAA_14 PF13173.1 KFH42072.1 - 0.065 13.1 0.3 0.14 12.0 0.2 1.6 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 KFH42072.1 - 0.09 12.4 0.0 4 7.1 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 KFH42072.1 - 0.095 12.3 0.0 0.2 11.3 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase Glyco_hydro_3_C PF01915.17 KFH42072.1 - 0.11 11.9 0.8 0.14 11.6 0.4 1.3 1 1 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain AAA_22 PF13401.1 KFH42072.1 - 0.12 12.4 0.0 1.7 8.7 0.0 2.4 1 1 1 2 2 2 0 AAA domain ETC_C1_NDUFA4 PF04800.7 KFH42073.1 - 2.7e-36 123.4 0.2 5e-36 122.5 0.1 1.5 1 0 0 1 1 1 1 ETC complex I subunit conserved region Lambda_tail_I PF06805.7 KFH42073.1 - 0.073 12.8 0.0 0.72 9.7 0.0 2.3 2 0 0 2 2 2 0 Bacteriophage lambda tail assembly protein I NIR_SIR PF01077.17 KFH42074.1 - 2e-52 176.6 0.2 9e-47 158.3 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 KFH42074.1 - 7.3e-30 102.4 0.0 5.4e-15 54.7 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 KFH42074.1 - 6.4e-27 94.3 0.1 2.5e-26 92.3 0.0 2.1 2 0 0 2 2 2 1 Flavodoxin POR_N PF01855.14 KFH42074.1 - 1e-06 28.4 0.3 2.9e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Flavodoxin_5 PF12724.2 KFH42074.1 - 0.1 12.5 0.0 0.34 10.8 0.0 1.9 2 0 0 2 2 2 0 Flavodoxin domain Pyr_redox_2 PF07992.9 KFH42075.1 - 2e-24 86.6 0.0 2.8e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFH42075.1 - 9.5e-15 54.7 0.7 1.1e-10 41.7 0.0 3.3 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 KFH42075.1 - 7.3e-07 28.0 0.3 7.3e-07 28.0 0.2 1.9 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 KFH42075.1 - 1.5e-05 25.0 0.9 3.4e-05 23.9 0.2 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KFH42075.1 - 1.5e-05 24.4 0.7 4.8e-05 22.8 0.5 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 KFH42075.1 - 0.0002 20.5 1.5 0.0002 20.5 1.1 2.1 2 0 0 2 2 2 1 EF hand Pyr_redox_3 PF13738.1 KFH42075.1 - 0.00095 19.2 0.0 0.66 10.0 0.0 3.1 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFH42075.1 - 0.0054 15.6 0.3 1.7 7.3 0.0 2.8 3 0 0 3 3 3 2 FAD binding domain EF-hand_8 PF13833.1 KFH42075.1 - 0.11 12.0 0.1 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair DUF2360 PF10152.4 KFH42076.1 - 0.029 14.6 1.7 0.04 14.2 1.2 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Mito_fiss_reg PF05308.6 KFH42076.1 - 0.56 9.5 8.0 0.66 9.2 5.6 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF605 PF04652.11 KFH42076.1 - 7.9 5.7 13.3 8.7 5.6 9.2 1.0 1 0 0 1 1 1 0 Vta1 like RNase_H2_suC PF08615.6 KFH42077.1 - 6.4e-23 81.1 0.0 9.1e-23 80.6 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF3715 PF12509.3 KFH42077.1 - 0.093 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3715) Peptidase_M50B PF13398.1 KFH42078.1 - 8.6e-58 195.0 18.9 1.1e-57 194.7 13.1 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.17 KFH42078.1 - 0.0059 15.5 0.0 0.0059 15.5 0.0 2.5 3 1 0 3 3 3 1 Peptidase family M50 MLANA PF14991.1 KFH42078.1 - 0.58 10.1 6.9 0.12 12.3 0.8 2.2 1 1 1 2 2 2 0 Protein melan-A YlaC PF10777.4 KFH42078.1 - 0.79 9.2 5.6 0.25 10.8 0.2 2.1 2 0 0 2 2 2 0 Inner membrane protein YlaC XPG_I_2 PF12813.2 KFH42080.1 - 3.7e-52 177.2 0.0 6.9e-52 176.3 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.13 KFH42080.1 - 0.0042 17.1 0.0 0.0087 16.0 0.0 1.6 1 0 0 1 1 1 1 XPG I-region Glyco_hydro_18 PF00704.23 KFH42081.1 - 3.5e-16 59.5 0.4 3.6e-15 56.2 0.0 1.9 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 TRAPPC-Trs85 PF12739.2 KFH42082.1 - 6.2e-112 374.2 3.0 2.2e-111 372.4 1.9 1.8 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit M20_dimer PF07687.9 KFH42082.1 - 0.098 12.4 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Peptidase dimerisation domain RNase_T PF00929.19 KFH42083.1 - 1.2e-26 93.9 0.0 1.8e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 KFH42083.1 - 0.00055 19.4 0.0 0.0014 18.1 0.0 1.6 1 1 0 1 1 1 1 3'-5' exonuclease Tub_2 PF04525.7 KFH42085.1 - 1.7e-24 86.2 0.0 2.1e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 Tubby C 2 Receptor_IA-2 PF11548.3 KFH42085.1 - 0.049 13.5 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein-tyrosine phosphatase receptor IA-2 DUF4469 PF14734.1 KFH42085.1 - 0.12 12.2 0.5 0.96 9.3 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4469) with IG-like fold APH PF01636.18 KFH42086.1 - 4.1e-12 46.3 1.0 3.1e-11 43.4 0.7 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFH42086.1 - 0.00028 20.5 0.1 0.00028 20.5 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.20 KFH42086.1 - 0.16 11.1 0.0 0.36 9.9 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain Snf7 PF03357.16 KFH42087.1 - 1.1e-19 70.4 16.4 1.7e-19 69.8 11.4 1.3 1 0 0 1 1 1 1 Snf7 DUF2067 PF09840.4 KFH42087.1 - 0.0036 16.8 3.7 0.0045 16.5 1.6 1.8 1 1 1 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2067) E3_binding PF02817.12 KFH42087.1 - 0.017 14.7 0.4 0.045 13.3 0.3 1.7 1 0 0 1 1 1 0 e3 binding domain PspA_IM30 PF04012.7 KFH42087.1 - 0.88 8.8 31.5 0.34 10.2 17.6 2.7 1 1 1 2 2 2 0 PspA/IM30 family Bud13 PF09736.4 KFH42088.1 - 4.9e-48 163.0 15.6 4.9e-48 163.0 10.8 2.5 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex DUF4350 PF14258.1 KFH42089.1 - 1.2e-05 25.4 0.0 5.7e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4350) ADH_zinc_N PF00107.21 KFH42089.1 - 0.063 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF1237 PF06824.6 KFH42090.1 - 1e-178 594.2 0.0 1.2e-178 594.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Kei1 PF08552.6 KFH42091.1 - 1.7e-46 158.2 11.8 4.3e-46 156.9 8.2 1.6 1 1 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 DUF2417 PF10329.4 KFH42091.1 - 0.11 11.8 4.5 0.15 11.4 3.1 1.1 1 0 0 1 1 1 0 Region of unknown function (DUF2417) DUF2269 PF10027.4 KFH42091.1 - 0.13 12.0 7.6 0.16 11.7 2.4 2.2 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) DUF843 PF05814.6 KFH42091.1 - 3.3 7.5 5.0 9.4 6.1 0.4 2.5 2 1 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) CDC27 PF09507.5 KFH42092.1 - 1.8e-76 258.0 29.8 3.2e-76 257.2 20.7 1.3 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Nop25 PF09805.4 KFH42092.1 - 0.44 10.6 14.5 1.1 9.3 10.0 1.7 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Methyltransf_12 PF08242.7 KFH42093.1 - 2.9e-05 24.4 0.0 4.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH42093.1 - 0.00017 22.1 0.1 0.00024 21.6 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH42093.1 - 0.0002 20.9 0.0 0.00026 20.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH42093.1 - 0.00027 21.3 0.1 0.00049 20.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH42093.1 - 0.0065 16.2 0.0 0.012 15.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PRK PF00485.13 KFH42094.1 - 7.9e-55 185.4 0.0 1.2e-54 184.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 KFH42094.1 - 5.8e-40 136.7 0.0 9e-40 136.0 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 KFH42094.1 - 2.2e-10 41.3 0.0 7e-10 39.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFH42094.1 - 1.4e-06 28.6 0.0 3.1e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 KFH42094.1 - 0.00019 21.0 0.0 0.00041 20.0 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 KFH42094.1 - 0.00077 19.3 0.0 0.018 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KFH42094.1 - 0.0032 16.9 0.1 0.01 15.3 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.1 KFH42094.1 - 0.0032 17.4 0.0 0.0094 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 KFH42094.1 - 0.01 15.7 0.0 0.024 14.5 0.0 1.7 2 0 0 2 2 1 0 Cytidylate kinase-like family NB-ARC PF00931.17 KFH42094.1 - 0.01 14.7 0.0 0.022 13.6 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain FtsK_SpoIIIE PF01580.13 KFH42094.1 - 0.011 15.1 0.0 0.028 13.9 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.22 KFH42094.1 - 0.012 15.8 0.3 0.037 14.3 0.1 1.8 2 0 0 2 2 1 0 ABC transporter RNA_helicase PF00910.17 KFH42094.1 - 0.012 15.7 0.0 0.041 14.0 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.1 KFH42094.1 - 0.013 15.5 0.1 0.037 14.0 0.0 1.8 2 1 0 2 2 1 0 AAA ATPase domain AAA_22 PF13401.1 KFH42094.1 - 0.015 15.4 0.0 0.07 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 KFH42094.1 - 0.043 12.7 0.0 0.081 11.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein SKI PF01202.17 KFH42094.1 - 0.044 13.6 0.0 0.16 11.8 0.0 2.0 2 0 0 2 2 1 0 Shikimate kinase Pribosyltran PF00156.22 KFH42094.1 - 0.051 13.3 0.0 0.27 10.9 0.0 2.1 2 0 0 2 2 2 0 Phosphoribosyl transferase domain APS_kinase PF01583.15 KFH42094.1 - 0.062 12.9 0.1 0.18 11.4 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase MobB PF03205.9 KFH42094.1 - 0.064 12.9 0.1 0.16 11.6 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 KFH42094.1 - 0.082 11.9 0.0 0.15 11.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin CoaE PF01121.15 KFH42094.1 - 0.1 11.9 0.2 0.45 9.8 0.1 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase DUF87 PF01935.12 KFH42094.1 - 0.12 12.1 0.1 0.27 11.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF258 PF03193.11 KFH42094.1 - 0.14 11.3 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Pribosyltran_N PF13793.1 KFH42095.1 - 1.3e-42 144.2 0.0 5.5e-41 138.9 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KFH42095.1 - 6.2e-35 120.6 0.4 4.9e-29 101.3 0.1 2.7 2 1 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KFH42095.1 - 3.4e-06 26.7 0.2 0.0013 18.5 0.0 2.9 3 0 0 3 3 3 2 Phosphoribosyl transferase domain Chitin_synth_1 PF01644.12 KFH42096.1 - 3.7e-84 280.4 0.6 5.8e-84 279.8 0.1 1.6 2 0 0 2 2 2 1 Chitin synthase Chitin_synth_1N PF08407.6 KFH42096.1 - 3.3e-32 110.0 0.1 6.3e-32 109.1 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KFH42096.1 - 1.3e-24 86.5 4.6 6.7e-21 74.2 0.0 2.4 1 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KFH42096.1 - 8.8e-10 38.5 0.2 8.8e-10 38.5 0.1 2.4 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KFH42096.1 - 9.5e-06 25.5 0.0 2.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Nop53 PF07767.6 KFH42097.1 - 2.7e-99 332.8 33.2 3.2e-99 332.5 23.0 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) MCM PF00493.18 KFH42098.1 - 6.4e-137 455.7 0.4 1.3e-136 454.8 0.3 1.5 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KFH42098.1 - 4.7e-21 75.5 0.0 2.5e-20 73.1 0.0 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KFH42098.1 - 2.6e-07 30.0 0.0 7.2e-07 28.5 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KFH42098.1 - 0.0014 18.1 0.0 0.0032 16.9 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 KFH42098.1 - 0.0024 17.4 0.0 0.0057 16.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DJ-1_PfpI PF01965.19 KFH42099.1 - 4.1e-29 100.9 0.1 5.5e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 KFH42099.1 - 2.4e-12 46.1 0.1 6.6e-12 44.7 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of DJ-1_PfpI family DUF4066 PF13278.1 KFH42099.1 - 0.0027 17.0 0.0 0.0057 15.9 0.0 1.6 2 0 0 2 2 2 1 Putative amidotransferase GATase_3 PF07685.9 KFH42099.1 - 0.0035 16.9 0.0 0.0051 16.4 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Glyoxalase_2 PF12681.2 KFH42100.1 - 5.6e-11 43.0 0.0 6.5e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KFH42100.1 - 4.9e-07 29.7 0.0 1e-06 28.7 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Sorb PF02208.11 KFH42100.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Sorbin homologous domain Glyoxalase_4 PF13669.1 KFH42100.1 - 0.028 14.4 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Ribonucleas_3_3 PF14622.1 KFH42101.1 - 3.4e-20 72.3 0.0 7.1e-20 71.2 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease-III-like 2-Hacid_dh_C PF02826.14 KFH42102.1 - 1.9e-33 115.1 0.0 2.4e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFH42102.1 - 1.4e-10 40.7 0.0 1.8e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KFH42102.1 - 0.0071 16.1 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Ank_2 PF12796.2 KFH42104.1 - 4.7e-32 110.1 5.1 2.4e-15 56.6 0.0 4.1 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFH42104.1 - 2.9e-26 89.9 18.0 1.2e-06 28.0 0.0 8.1 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.1 KFH42104.1 - 4e-19 66.8 8.1 0.00055 19.9 0.0 8.3 8 1 2 10 10 10 4 Ankyrin repeat Ank_5 PF13857.1 KFH42104.1 - 2.6e-18 65.6 14.9 4e-08 33.2 0.1 6.9 2 2 5 7 7 7 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFH42104.1 - 2.5e-14 53.2 11.8 4.7e-06 26.9 0.1 6.0 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Thioesterase PF00975.15 KFH42105.1 - 4.1e-15 56.6 0.0 8.4e-15 55.6 0.0 1.5 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 KFH42105.1 - 4.6e-09 36.4 0.1 5.6e-09 36.2 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH42105.1 - 1.4e-05 24.8 0.0 2.1e-05 24.3 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KFH42105.1 - 4e-05 23.1 0.0 6.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 KFH42105.1 - 0.0013 18.3 0.0 0.0018 17.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 KFH42105.1 - 0.0015 18.0 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cutinase PF01083.17 KFH42105.1 - 0.047 13.4 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 Cutinase PGAP1 PF07819.8 KFH42105.1 - 0.062 12.8 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein UvdE PF03851.9 KFH42106.1 - 5.2e-107 356.9 0.0 8.6e-107 356.2 0.0 1.3 1 0 0 1 1 1 1 UV-endonuclease UvdE SET PF00856.23 KFH42106.1 - 2.1e-12 47.6 0.0 9.8e-12 45.4 0.0 2.1 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.6 KFH42106.1 - 2.1e-08 34.1 0.1 5.6e-08 32.7 0.1 1.7 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding IF3_C PF00707.17 KFH42107.1 - 1.2e-13 50.6 0.4 2e-13 49.8 0.3 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 KFH42107.1 - 2.2e-07 30.4 4.5 3.3e-07 29.8 3.1 1.3 1 0 0 1 1 1 1 Mitochondrial translation initiation factor ComA PF02679.10 KFH42107.1 - 0.085 11.8 0.9 0.13 11.2 0.6 1.2 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) Formyl_trans_N PF00551.14 KFH42108.1 - 5.6e-39 133.5 0.0 6.6e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase MannoseP_isomer PF01050.13 KFH42108.1 - 0.017 14.7 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Barstar PF01337.13 KFH42108.1 - 0.099 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Barstar (barnase inhibitor) Amidase PF01425.16 KFH42109.1 - 9.8e-22 77.3 0.5 2.5e-21 76.0 0.4 1.7 1 1 0 1 1 1 1 Amidase ACC_epsilon PF13822.1 KFH42110.1 - 0.023 15.0 0.1 0.037 14.3 0.1 1.3 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit Fungal_trans PF04082.13 KFH42112.1 - 2.7e-17 62.5 0.0 4.3e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH42112.1 - 0.011 15.6 7.6 0.022 14.6 5.3 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Formyl_trans_N PF00551.14 KFH42113.1 - 4.4e-39 133.8 0.1 5.6e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.20 KFH42113.1 - 5.4e-10 38.5 0.0 1.6e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 KFH42113.1 - 0.00018 21.1 0.0 0.00065 19.3 0.0 2.1 2 1 0 2 2 2 1 ACT domain ACC_central PF08326.7 KFH42114.1 - 0.016 13.3 0.0 0.023 12.8 0.0 1.1 1 0 0 1 1 1 0 Acetyl-CoA carboxylase, central region Sugar_tr PF00083.19 KFH42115.1 - 9.5e-72 241.9 26.6 1.3e-71 241.5 18.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH42115.1 - 7.4e-16 57.8 38.9 4.5e-11 42.0 13.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily KAT11 PF08214.6 KFH42116.1 - 1.4e-94 317.0 0.0 2.3e-94 316.3 0.0 1.4 1 0 0 1 1 1 1 Histone acetylation protein Med15 PF09606.5 KFH42116.1 - 0.051 11.7 8.8 0.092 10.9 6.1 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal ketoacyl-synt PF00109.21 KFH42117.1 - 2.9e-69 233.3 0.0 1.3e-68 231.1 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KFH42117.1 - 3.9e-59 199.3 1.3 1.1e-58 197.8 0.9 1.9 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 KFH42117.1 - 1.2e-55 189.1 0.2 2.1e-55 188.2 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KFH42117.1 - 2e-47 161.8 0.0 3.4e-47 161.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KFH42117.1 - 1.8e-45 154.8 1.8 2.3e-45 154.5 0.2 2.1 2 0 0 2 2 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KFH42117.1 - 3.5e-38 130.1 0.6 1.1e-37 128.5 0.4 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KFH42117.1 - 3e-23 81.8 0.0 4e-21 74.9 0.0 2.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KFH42117.1 - 9.1e-19 67.7 0.1 3e-18 66.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KFH42117.1 - 4.9e-13 50.0 0.0 7.9e-11 42.9 0.0 3.3 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KFH42117.1 - 2.5e-12 46.8 0.0 5.4e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH42117.1 - 3.3e-10 39.7 0.0 7.3e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH42117.1 - 1.1e-09 38.9 0.2 8.5e-09 35.9 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH42117.1 - 7.8e-09 35.9 0.0 4e-08 33.6 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFH42117.1 - 5.1e-08 32.3 0.0 1.3e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KFH42117.1 - 3.6e-06 27.2 0.0 1.4e-05 25.3 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KFH42117.1 - 1.5e-05 25.1 0.1 4.2e-05 23.7 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_16 PF10294.4 KFH42117.1 - 0.0089 15.4 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_28 PF02636.12 KFH42117.1 - 0.021 14.2 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DREV PF05219.7 KFH42117.1 - 0.036 12.9 0.0 0.069 12.0 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase NAD_binding_10 PF13460.1 KFH42117.1 - 0.13 12.2 4.9 9.5 6.1 0.1 4.0 4 0 0 4 4 4 0 NADH(P)-binding TRM13 PF05206.9 KFH42117.1 - 0.42 9.8 0.0 0.76 8.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase TRM13 NmrA PF05368.8 KFH42117.1 - 0.5 9.5 1.2 23 4.1 0.1 2.4 2 0 0 2 2 2 0 NmrA-like family zf-RING_2 PF13639.1 KFH42118.1 - 3.6e-11 42.7 2.4 1.8e-09 37.2 0.4 2.4 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 KFH42118.1 - 3.6e-07 30.1 0.2 5.4e-06 26.4 0.1 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KFH42118.1 - 1.1e-05 24.9 0.8 0.00014 21.5 0.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFH42118.1 - 2.8e-05 24.0 2.1 0.00022 21.1 0.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFH42118.1 - 0.00013 21.7 0.8 0.00024 20.8 0.1 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 KFH42118.1 - 0.00018 21.1 0.2 0.00018 21.1 0.2 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFH42118.1 - 0.0037 16.8 5.2 0.0044 16.6 0.2 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KFH42118.1 - 0.039 13.9 5.3 1.5 8.8 2.4 2.6 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_6 PF14835.1 KFH42118.1 - 0.11 12.3 0.3 1.2 8.9 0.1 2.3 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING-like PF08746.6 KFH42118.1 - 0.26 11.3 2.0 0.54 10.2 1.4 1.5 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.2 KFH42118.1 - 0.61 10.1 2.7 0.41 10.7 0.4 1.8 2 0 0 2 2 2 0 RING-variant domain AMP-binding PF00501.23 KFH42119.1 - 6.2e-63 212.6 0.0 8.4e-63 212.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFH42119.1 - 2.4e-13 50.8 0.0 7.8e-13 49.1 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 KFH42120.1 - 0 1651.1 6.0 4.9e-84 282.1 0.0 6.3 6 0 0 6 6 6 6 AMP-binding enzyme Condensation PF00668.15 KFH42120.1 - 0 1034.1 8.2 1.7e-46 158.4 0.0 8.9 8 1 0 8 8 8 8 Condensation domain PP-binding PF00550.20 KFH42120.1 - 1.3e-72 240.0 6.7 4.3e-10 39.7 0.0 8.9 8 0 0 8 8 8 7 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KFH42120.1 - 4.4e-32 110.8 0.6 6.4e-07 30.2 0.0 7.1 6 0 0 6 6 6 6 AMP-binding enzyme C-terminal domain AATase PF07247.7 KFH42120.1 - 0.00049 18.7 0.0 4.5 5.7 0.0 4.9 6 0 0 6 6 6 2 Alcohol acetyltransferase Transferase PF02458.10 KFH42120.1 - 0.00079 17.9 0.0 8.1 4.7 0.1 3.8 4 0 0 4 4 4 2 Transferase family DUF1244 PF06844.6 KFH42120.1 - 0.41 10.4 0.9 1e+02 2.8 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1244) Glycos_transf_2 PF00535.21 KFH42120.1 - 0.78 9.3 0.0 3.2 7.3 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 2 Cytochrom_NNT PF03264.9 KFH42120.1 - 5.5 6.3 0.8 10 5.5 0.0 1.7 2 0 0 2 2 2 0 NapC/NirT cytochrome c family, N-terminal region SRP54 PF00448.17 KFH42121.1 - 2.2e-76 255.6 2.0 2.2e-76 255.6 1.4 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 KFH42121.1 - 1.2e-25 89.7 6.5 1.2e-25 89.7 4.5 4.1 5 1 1 6 6 3 1 Signal peptide binding domain SRP54_N PF02881.14 KFH42121.1 - 1.2e-12 47.7 0.2 3e-12 46.4 0.2 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 KFH42121.1 - 6.2e-10 38.7 0.1 1.6e-09 37.4 0.1 1.7 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KFH42121.1 - 2.1e-06 27.6 0.0 4.8e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KFH42121.1 - 2.1e-05 24.2 0.0 5.8e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 KFH42121.1 - 6.5e-05 23.7 0.0 0.00014 22.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 KFH42121.1 - 0.00025 20.4 0.2 0.0011 18.3 0.1 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 KFH42121.1 - 0.00047 19.0 0.6 0.0021 16.8 0.4 2.2 1 1 0 1 1 1 1 ArgK protein SRPRB PF09439.5 KFH42121.1 - 0.0009 18.4 1.4 2.1 7.5 0.9 3.2 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 KFH42121.1 - 0.00097 19.2 0.1 0.0051 16.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 KFH42121.1 - 0.0016 18.1 0.1 0.0032 17.1 0.1 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.1 KFH42121.1 - 0.0024 17.9 0.1 0.0061 16.5 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 KFH42121.1 - 0.005 17.1 0.0 0.012 15.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KFH42121.1 - 0.0061 15.9 0.8 0.023 14.0 0.1 2.2 2 0 0 2 2 2 1 Thymidylate kinase AAA_31 PF13614.1 KFH42121.1 - 0.0067 16.3 0.0 1.7 8.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.12 KFH42121.1 - 0.01 15.3 0.3 0.045 13.2 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.7 KFH42121.1 - 0.011 14.8 0.1 0.026 13.6 0.0 1.7 2 0 0 2 2 1 0 Zeta toxin 6PF2K PF01591.13 KFH42121.1 - 0.021 13.9 0.1 0.035 13.1 0.1 1.4 1 1 0 1 1 1 0 6-phosphofructo-2-kinase AAA_28 PF13521.1 KFH42121.1 - 0.023 14.6 0.2 0.056 13.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.4 KFH42121.1 - 0.037 12.6 0.0 0.1 11.2 0.0 1.7 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Arf PF00025.16 KFH42121.1 - 0.076 12.2 0.4 0.26 10.4 0.0 2.0 3 0 0 3 3 3 0 ADP-ribosylation factor family AAA PF00004.24 KFH42121.1 - 0.092 12.9 0.5 0.42 10.8 0.4 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) VirE PF05272.6 KFH42121.1 - 0.096 12.1 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Virulence-associated protein E Torsin PF06309.6 KFH42121.1 - 0.097 12.5 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Torsin DUF3786 PF12654.2 KFH42121.1 - 0.12 11.6 0.8 5.4 6.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3786) DHH PF01368.15 KFH42121.1 - 0.12 11.9 0.1 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 DHH family NTPase_1 PF03266.10 KFH42121.1 - 0.2 11.3 2.0 2.4 7.8 1.4 2.2 1 1 0 1 1 1 0 NTPase Ank_2 PF12796.2 KFH42122.1 - 3e-14 53.1 0.3 2.1e-07 31.2 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFH42122.1 - 8.8e-06 25.2 0.5 0.067 13.0 0.0 4.2 3 2 1 4 4 4 1 Ankyrin repeat Ank_3 PF13606.1 KFH42122.1 - 3e-05 23.8 0.1 1.8 9.0 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat HEM4 PF02602.10 KFH42122.1 - 0.0054 15.9 0.0 0.0081 15.4 0.0 1.3 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Ank_5 PF13857.1 KFH42122.1 - 0.0055 16.9 0.1 0.3 11.4 0.0 3.3 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFH42122.1 - 0.01 16.3 0.1 3.5 8.2 0.0 3.2 2 1 2 4 4 4 0 Ankyrin repeats (many copies) Alb1 PF09135.6 KFH42123.1 - 1.6e-22 80.1 11.9 2.4e-22 79.6 8.2 1.2 1 0 0 1 1 1 1 Alb1 TMEM247 PF15444.1 KFH42123.1 - 0.43 10.3 2.5 0.55 10.0 1.7 1.3 1 1 0 1 1 1 0 Transmembrane protein 247 Adap_comp_sub PF00928.16 KFH42124.1 - 1.1e-90 303.2 0.0 1.5e-90 302.8 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KFH42124.1 - 4.2e-08 33.0 0.3 6.9e-08 32.3 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RecU PF03838.9 KFH42124.1 - 0.058 12.9 0.3 2.8 7.4 0.1 2.3 2 0 0 2 2 2 0 Recombination protein U Opi1 PF08618.5 KFH42125.1 - 4.9e-81 272.8 0.0 3.4e-66 223.9 0.0 3.3 1 1 1 2 2 2 2 Transcription factor Opi1 Thymidylate_kin PF02223.12 KFH42126.1 - 2.9e-41 140.8 0.0 3.6e-41 140.5 0.0 1.2 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 KFH42126.1 - 1.2e-06 28.6 0.0 1.6e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KFH42126.1 - 0.048 12.8 0.0 0.071 12.3 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_18 PF13238.1 KFH42126.1 - 0.089 13.1 0.0 0.47 10.7 0.0 2.3 2 1 0 2 2 2 0 AAA domain Zn_clus PF00172.13 KFH42127.1 - 9.4e-09 35.0 9.5 1.7e-08 34.1 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFH42127.1 - 2e-05 23.3 0.1 3.2e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Innate_immun PF12782.2 KFH42127.1 - 0.028 13.6 10.1 0.044 13.0 7.0 1.3 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Zip PF02535.17 KFH42127.1 - 0.14 11.1 9.3 0.2 10.6 6.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 KFH42127.1 - 0.47 9.7 14.6 0.7 9.2 10.1 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region BAF1_ABF1 PF04684.8 KFH42127.1 - 0.69 8.6 16.5 1 8.1 11.4 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor ECH PF00378.15 KFH42128.1 - 5e-52 176.4 0.0 9.7e-52 175.5 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 KFH42128.1 - 0.042 13.9 0.0 0.093 12.8 0.0 1.6 2 0 0 2 2 2 0 2-enoyl-CoA Hydratase C-terminal region WD40 PF00400.27 KFH42129.1 - 3.8e-14 51.9 3.0 6.4e-05 22.6 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat PQQ_3 PF13570.1 KFH42129.1 - 0.1 12.9 0.9 0.59 10.4 0.0 2.7 3 1 0 3 3 3 0 PQQ-like domain DUF2710 PF10921.3 KFH42129.1 - 0.13 12.4 0.2 3.1 7.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2710) TPR_1 PF00515.23 KFH42130.1 - 1.6e-11 43.2 3.8 8.6e-05 21.9 0.0 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFH42130.1 - 1.4e-09 37.4 7.1 8.7e-08 31.7 1.3 3.6 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 KFH42130.1 - 2.3e-09 36.4 11.7 0.00049 19.8 0.1 5.4 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFH42130.1 - 4.6e-08 32.2 2.3 0.0025 17.4 0.1 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFH42130.1 - 6.4e-07 29.2 20.8 1e-05 25.3 1.3 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFH42130.1 - 8.1e-06 26.0 12.0 0.00011 22.4 0.1 5.5 5 1 0 5 5 4 1 Tetratricopeptide repeat Apc3 PF12895.2 KFH42130.1 - 0.00018 21.5 13.8 0.0013 18.8 0.6 4.6 5 0 0 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 KFH42130.1 - 0.00027 21.5 0.1 0.00027 21.5 0.0 5.9 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFH42130.1 - 0.00046 19.7 5.5 1 9.3 0.0 5.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFH42130.1 - 0.001 19.5 16.8 0.023 15.3 0.0 7.0 7 1 0 7 7 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFH42130.1 - 0.006 16.9 8.9 5.2 7.7 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat NACHT PF05729.7 KFH42130.1 - 0.013 15.1 0.0 0.033 13.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.1 KFH42130.1 - 0.017 15.2 0.0 0.13 12.4 0.0 2.5 3 0 0 3 3 2 0 AAA domain TPR_17 PF13431.1 KFH42130.1 - 0.023 14.8 5.4 0.75 10.1 0.1 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat Acetyltransf_11 PF13720.1 KFH42130.1 - 0.03 14.5 0.2 3.2 8.0 0.0 3.1 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 TPR_10 PF13374.1 KFH42130.1 - 0.087 12.7 4.9 14 5.7 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-RING_5 PF14634.1 KFH42130.1 - 0.79 9.4 4.6 1.6 8.5 3.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Nop14 PF04147.7 KFH42131.1 - 6.6 4.5 12.1 15 3.3 8.4 1.5 1 0 0 1 1 1 0 Nop14-like family Glyco_hydro_71 PF03659.9 KFH42132.1 - 1.9e-129 431.4 1.4 2.2e-129 431.3 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Metallophos PF00149.23 KFH42133.1 - 0.0014 18.0 5.4 0.0031 16.9 3.8 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.13 KFH42133.1 - 0.036 14.0 0.0 0.11 12.4 0.0 1.7 1 1 0 1 1 1 0 5'-nucleotidase, C-terminal domain Alpha-amylase PF00128.19 KFH42134.1 - 6.2e-65 219.6 0.3 1.4e-64 218.4 0.2 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 KFH42134.1 - 0.0066 14.2 0.1 0.082 10.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 70 hDGE_amylase PF14701.1 KFH42134.1 - 0.035 12.9 0.0 0.074 11.9 0.0 1.4 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme IlvC PF01450.14 KFH42134.1 - 0.037 13.9 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain DUF914 PF06027.7 KFH42135.1 - 9.9e-106 353.3 15.0 1.3e-105 352.9 10.4 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 KFH42135.1 - 3.9e-05 23.6 28.0 0.00041 20.3 5.7 2.5 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 KFH42135.1 - 0.35 9.7 15.7 0.5 9.2 10.9 1.2 1 0 0 1 1 1 0 UAA transporter family TPT PF03151.11 KFH42135.1 - 2.5 7.7 26.3 3.9 7.0 5.5 2.7 2 1 0 2 2 2 0 Triose-phosphate Transporter family Ctr PF04145.10 KFH42136.1 - 2.1e-39 134.8 1.8 2.5e-39 134.6 1.3 1.0 1 0 0 1 1 1 1 Ctr copper transporter family GDE_C PF06202.9 KFH42137.1 - 0.0068 15.1 0.1 0.32 9.6 0.0 2.3 2 0 0 2 2 2 2 Amylo-alpha-1,6-glucosidase 2OG-FeII_Oxy_3 PF13640.1 KFH42138.1 - 0.032 14.7 0.0 0.056 13.9 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 2OG-Fe_Oxy_2 PF10014.4 KFH42138.1 - 0.095 12.0 0.2 0.18 11.1 0.1 1.4 1 0 0 1 1 1 0 2OG-Fe dioxygenase Peptidase_S9 PF00326.16 KFH42139.1 - 0.00018 20.8 0.7 0.0086 15.3 0.8 2.4 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFH42139.1 - 0.00049 19.8 0.1 0.00083 19.1 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 KFH42139.1 - 0.0011 18.2 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Amino_oxidase PF01593.19 KFH42140.1 - 1.4e-41 143.0 1.5 8.4e-28 97.6 0.0 2.0 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KFH42140.1 - 2.7e-11 43.3 2.1 3.3e-11 43.0 0.3 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFH42140.1 - 3.3e-08 32.8 0.8 4.4e-07 29.1 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFH42140.1 - 5.9e-08 31.9 1.5 1.1e-07 31.1 1.1 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KFH42140.1 - 2.6e-07 29.4 0.3 8.2e-07 27.8 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 KFH42140.1 - 3.8e-07 29.5 1.3 6.3e-07 28.8 0.9 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFH42140.1 - 1.1e-06 28.6 0.1 0.00015 21.6 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFH42140.1 - 4.4e-06 25.9 1.0 6.8e-06 25.3 0.2 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 KFH42140.1 - 1.7e-05 24.9 0.4 7.1e-05 22.9 0.2 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFH42140.1 - 2.7e-05 23.2 0.4 0.00013 21.0 0.1 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.17 KFH42140.1 - 0.00023 20.1 0.9 0.00034 19.5 0.2 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.22 KFH42140.1 - 0.00073 19.8 0.1 0.0018 18.6 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KFH42140.1 - 0.076 12.5 0.1 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Complex1_LYR_1 PF13232.1 KFH42141.1 - 3.6e-15 55.9 0.6 4.8e-15 55.5 0.4 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KFH42141.1 - 6.5e-14 51.4 0.8 8.5e-14 51.1 0.6 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Abhydrolase_2 PF02230.11 KFH42142.1 - 6.3e-58 195.7 0.0 7.4e-58 195.5 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KFH42142.1 - 5.3e-11 42.4 0.1 2.1e-10 40.4 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFH42142.1 - 2.9e-08 33.8 2.0 0.00023 21.1 0.9 2.9 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KFH42142.1 - 2.5e-05 23.9 0.2 0.061 12.8 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.13 KFH42142.1 - 0.0001 21.6 0.0 0.00017 20.9 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.8 KFH42142.1 - 0.0045 16.4 0.0 0.025 14.0 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 KFH42142.1 - 0.01 15.0 1.3 0.12 11.5 0.0 2.6 3 0 0 3 3 3 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KFH42142.1 - 0.07 12.6 0.1 2.4 7.6 0.1 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold DUF1620 PF07774.8 KFH42143.1 - 5.3e-62 208.9 0.0 8.6e-62 208.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 KFH42143.1 - 5.5e-16 58.7 9.0 1.4e-11 44.2 0.8 3.0 2 1 1 3 3 3 2 PQQ-like domain PQQ PF01011.16 KFH42143.1 - 1.8e-08 33.4 0.5 0.011 15.2 0.0 5.3 5 0 0 5 5 5 2 PQQ enzyme repeat AMP-binding PF00501.23 KFH42144.1 - 1.9e-67 227.4 0.0 2.4e-67 227.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFH42144.1 - 1.6e-13 51.3 0.5 7.4e-13 49.2 0.3 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Glyco_hydro_71 PF03659.9 KFH42146.1 - 3.7e-137 456.8 1.6 4.8e-137 456.5 1.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4434 PF14488.1 KFH42146.1 - 0.048 13.4 0.1 0.11 12.2 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) RloB PF13707.1 KFH42146.1 - 0.24 11.0 0.0 0.36 10.4 0.0 1.2 1 0 0 1 1 1 0 RloB-like protein PAP_assoc PF03828.14 KFH42148.1 - 1.1e-16 60.5 0.3 2.4e-16 59.4 0.2 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KFH42148.1 - 3.5e-06 27.2 0.0 6.9e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Ferric_reduct PF01794.14 KFH42149.1 - 3.9e-19 68.9 8.8 3.9e-19 68.9 6.1 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KFH42149.1 - 8.3e-15 55.0 0.0 1.2e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KFH42149.1 - 1.8e-10 40.6 0.0 4e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 KFH42149.1 - 8.8e-06 26.2 0.0 2.5e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain GFA PF04828.9 KFH42150.1 - 1.1e-06 28.5 0.1 1.3e-06 28.2 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 KFH42150.1 - 0.25 10.5 0.2 0.25 10.5 0.1 2.1 3 0 0 3 3 3 0 zinc-ribbon domain 2-Hacid_dh_C PF02826.14 KFH42151.1 - 2.3e-38 131.1 0.0 1.6e-27 95.7 0.0 2.1 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFH42151.1 - 0.0065 15.9 0.0 0.016 14.6 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain CFEM PF05730.6 KFH42152.1 - 2.3e-12 46.5 11.6 3.7e-12 45.8 8.0 1.4 1 0 0 1 1 1 1 CFEM domain Gamma-thionin PF00304.15 KFH42152.1 - 0.032 14.2 2.3 0.034 14.1 0.7 1.6 2 0 0 2 2 2 0 Gamma-thionin family Herpes_IE1 PF07340.6 KFH42152.1 - 0.13 10.6 0.4 0.18 10.2 0.3 1.1 1 0 0 1 1 1 0 Cytomegalovirus IE1 protein Phage_holin_6 PF10746.4 KFH42152.1 - 1.6 8.4 8.2 2.3 7.9 0.4 2.5 2 0 0 2 2 2 0 Phage holin family 6 DUF1446 PF07287.6 KFH42153.1 - 9.3e-126 419.1 0.0 1.1e-125 418.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) LYTB PF02401.13 KFH42153.1 - 1e-05 24.6 0.0 2.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 LytB protein Zn_clus PF00172.13 KFH42154.1 - 0.00015 21.5 7.6 0.00015 21.5 5.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.23 KFH42155.1 - 1.1e-79 267.7 0.1 1.6e-79 267.2 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFH42155.1 - 4.7e-10 40.2 0.2 1.1e-09 39.1 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF4079 PF13301.1 KFH42155.1 - 0.016 15.2 3.5 0.034 14.1 2.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) FeoA PF04023.9 KFH42155.1 - 0.023 14.6 0.2 0.63 10.0 0.0 2.6 2 0 0 2 2 2 0 FeoA domain DUF2985 PF11204.3 KFH42155.1 - 0.11 12.3 1.4 0.73 9.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) zf-IS66 PF13005.2 KFH42155.1 - 0.13 12.2 0.5 0.66 10.0 0.0 2.3 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 Mpv17_PMP22 PF04117.7 KFH42156.1 - 2.3e-16 59.1 1.0 5.7e-16 57.8 0.4 1.9 2 0 0 2 2 2 1 Mpv17 / PMP22 family Sensor_TM1 PF13755.1 KFH42156.1 - 1.2 8.6 3.4 18 4.9 0.2 2.5 2 0 0 2 2 2 0 Sensor N-terminal transmembrane domain BCS1_N PF08740.6 KFH42157.1 - 6.1e-25 87.9 0.2 9.9e-25 87.2 0.2 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KFH42157.1 - 1.1e-23 83.8 0.0 1.9e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KFH42157.1 - 5e-05 22.4 0.0 8.5e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KFH42157.1 - 0.0012 19.6 0.0 0.0064 17.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFH42157.1 - 0.0023 17.9 0.0 0.0048 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 KFH42157.1 - 0.023 13.6 0.0 0.036 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 KFH42157.1 - 0.031 13.6 0.0 0.06 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF1869 PF08956.5 KFH42157.1 - 0.076 12.6 0.0 5.1 6.7 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1869) YL1_C PF08265.6 KFH42157.1 - 0.089 12.3 0.3 0.2 11.2 0.2 1.6 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain AAA_18 PF13238.1 KFH42157.1 - 0.095 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KFH42157.1 - 0.097 12.0 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.9 KFH42157.1 - 0.1 12.3 0.0 0.43 10.3 0.0 2.0 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KFH42157.1 - 0.14 11.8 0.0 0.4 10.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain TIP49 PF06068.8 KFH42157.1 - 0.16 10.6 0.0 0.24 10.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus RNA_helicase PF00910.17 KFH42157.1 - 0.18 11.9 0.0 0.45 10.7 0.0 1.7 2 0 0 2 2 1 0 RNA helicase ABC2_membrane PF01061.19 KFH42158.1 - 9.2e-86 286.3 59.7 6.6e-45 152.8 14.2 2.9 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 KFH42158.1 - 3e-35 119.9 6.9 7.8e-30 102.5 0.0 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.22 KFH42158.1 - 3.7e-32 111.4 0.0 1.4e-14 54.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 KFH42158.1 - 9.4e-15 54.4 40.5 3.8e-10 39.3 8.6 3.3 2 1 1 3 3 3 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 KFH42158.1 - 2.2e-08 34.0 0.0 7.2e-08 32.4 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KFH42158.1 - 3.5e-08 33.0 0.1 0.00046 19.6 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_21 PF13304.1 KFH42158.1 - 4.9e-06 26.7 0.0 0.0023 17.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFH42158.1 - 1.4e-05 25.2 0.3 0.0007 19.6 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.14 KFH42158.1 - 4.2e-05 23.0 0.0 0.0074 15.7 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 KFH42158.1 - 4.5e-05 24.2 0.0 0.0033 18.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KFH42158.1 - 7.9e-05 21.8 0.0 0.00019 20.6 0.0 1.6 2 0 0 2 2 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KFH42158.1 - 8.6e-05 21.9 0.0 0.0017 17.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KFH42158.1 - 0.00017 21.7 0.1 0.051 13.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 KFH42158.1 - 0.00027 20.6 0.1 0.023 14.3 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 KFH42158.1 - 0.00048 19.8 1.5 0.23 11.2 0.0 3.2 3 0 0 3 3 2 1 Part of AAA domain AAA_28 PF13521.1 KFH42158.1 - 0.0014 18.5 1.1 0.004 17.1 0.1 2.2 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 KFH42158.1 - 0.0015 18.1 0.2 0.4 10.3 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 KFH42158.1 - 0.0018 18.1 0.0 0.14 12.0 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KFH42158.1 - 0.0042 17.2 0.2 1.3 9.2 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KFH42158.1 - 0.0045 17.3 0.0 0.03 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KFH42158.1 - 0.0097 14.8 0.0 0.15 10.9 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_10 PF12846.2 KFH42158.1 - 0.0098 15.3 0.3 1.1 8.6 0.1 2.9 3 1 0 3 3 3 1 AAA-like domain MMR_HSR1 PF01926.18 KFH42158.1 - 0.011 15.7 0.0 0.57 10.1 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 KFH42158.1 - 0.011 15.1 0.0 0.48 9.8 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.1 KFH42158.1 - 0.016 15.5 0.1 0.13 12.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KFH42158.1 - 0.031 13.8 0.3 0.67 9.4 0.0 2.6 3 0 0 3 3 2 0 AAA domain SMC_N PF02463.14 KFH42158.1 - 0.052 12.7 0.0 6 6.0 0.0 2.5 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Arch_ATPase PF01637.13 KFH42158.1 - 0.053 13.2 0.0 2.6 7.6 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase AAA_15 PF13175.1 KFH42158.1 - 0.055 12.5 0.0 0.094 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Miro PF08477.8 KFH42158.1 - 0.085 13.3 0.0 3.6 8.0 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein PduV-EutP PF10662.4 KFH42158.1 - 0.26 10.7 0.2 0.92 8.9 0.1 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 KFH42158.1 - 0.28 11.3 0.0 2.6 8.2 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Pantoate_ligase PF02569.10 KFH42158.1 - 0.32 9.7 0.0 0.53 8.9 0.0 1.2 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase Septin PF00735.13 KFH42158.1 - 0.34 9.8 0.1 6.3 5.7 0.0 2.2 2 0 0 2 2 2 0 Septin ADH_N PF08240.7 KFH42159.1 - 4.7e-29 100.3 0.1 7.9e-29 99.6 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFH42159.1 - 1.9e-16 59.7 0.0 2.9e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KFH42159.1 - 8.2e-05 22.1 0.3 0.00015 21.2 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated CVNH PF08881.5 KFH42160.1 - 6.4e-13 48.8 2.5 1.3e-11 44.6 0.4 2.1 1 1 1 2 2 2 2 CVNH domain Glyco_hydro_75 PF07335.6 KFH42161.1 - 1e-38 132.6 0.2 1.3e-38 132.3 0.1 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 SMI1_KNR4 PF09346.5 KFH42161.1 - 0.012 15.6 0.2 0.068 13.1 0.1 2.2 1 1 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) His_Phos_1 PF00300.17 KFH42164.1 - 7.8e-22 78.0 0.2 2.2e-21 76.5 0.1 1.8 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) adh_short PF00106.20 KFH42165.1 - 4.8e-18 65.6 1.5 6.3e-18 65.2 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH42165.1 - 4.6e-09 36.1 0.5 9.3e-09 35.2 0.3 1.5 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KFH42165.1 - 1.3e-07 31.6 0.0 1.5e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 KFH42165.1 - 0.0024 17.6 0.0 0.0047 16.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KFH42165.1 - 0.019 14.4 0.3 0.027 13.8 0.2 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KFH42165.1 - 0.025 13.4 0.1 0.038 12.8 0.1 1.3 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Abhydrolase_2 PF02230.11 KFH42166.1 - 7.1e-33 113.8 0.0 2.9e-24 85.7 0.0 2.3 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KFH42166.1 - 2.3e-05 24.4 0.1 9.3e-05 22.4 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH42166.1 - 3.3e-05 23.6 0.0 0.00013 21.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFH42166.1 - 0.0007 18.8 0.0 0.0013 18.0 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 KFH42166.1 - 0.064 12.5 0.0 0.094 11.9 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Lipoxygenase PF00305.14 KFH42167.1 - 1.7e-21 75.9 0.0 2.7e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Lipoxygenase DUF3659 PF12396.3 KFH42168.1 - 4.4e-116 378.6 61.1 3.6e-23 81.0 2.2 6.6 6 0 0 6 6 6 6 Protein of unknown function (DUF3659) CorA PF01544.13 KFH42168.1 - 0.13 11.2 0.3 0.2 10.6 0.2 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein CDC27 PF09507.5 KFH42170.1 - 4.9 6.2 29.2 5.7 6.0 20.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CENP-T PF15511.1 KFH42170.1 - 7.9 5.6 37.0 10 5.2 25.6 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF72 PF01904.13 KFH42172.1 - 0.051 13.3 0.0 0.48 10.1 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function DUF72 AMP-binding PF00501.23 KFH42173.1 - 5.6e-93 311.5 0.2 7.5e-93 311.1 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFH42173.1 - 6.9e-15 55.7 0.4 5.2e-14 52.9 0.1 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Esterase_phd PF10503.4 KFH42174.1 - 1.6e-20 73.2 0.2 2.3e-20 72.7 0.1 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KFH42174.1 - 1.8e-08 33.8 0.0 1.8e-08 33.8 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.23 KFH42174.1 - 0.0025 16.5 0.1 0.03 13.0 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFH42174.1 - 0.024 14.2 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KFH42174.1 - 0.028 14.2 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family ADH_zinc_N PF00107.21 KFH42175.1 - 3.9e-19 68.4 0.0 6.1e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFH42175.1 - 9.6e-06 26.5 0.0 1.8e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.3 KFH42175.1 - 0.15 11.2 0.0 0.57 9.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2855) Kinesin PF00225.18 KFH42176.1 - 1.3e-90 303.5 0.0 1.3e-90 303.5 0.0 3.1 3 0 0 3 3 3 2 Kinesin motor domain 2OG-FeII_Oxy_2 PF13532.1 KFH42177.1 - 2.6e-16 60.0 0.0 7.3e-16 58.5 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KFH42177.1 - 7.6e-10 38.9 0.0 2.1e-09 37.5 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily ERCC4 PF02732.10 KFH42178.1 - 1.7e-11 44.0 0.0 4.9e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 ERCC4 domain SAPS PF04499.10 KFH42178.1 - 0.01 14.5 0.2 0.014 14.0 0.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein HrpA_pilin PF09589.5 KFH42178.1 - 0.53 10.7 4.9 1.3 9.4 3.4 1.6 1 0 0 1 1 1 0 HrpA pilus formation protein Zn_clus PF00172.13 KFH42179.1 - 3.3e-06 26.8 12.4 5.7e-06 26.1 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Piwi PF02171.12 KFH42180.1 - 3.5e-72 242.9 0.0 5.1e-72 242.3 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 KFH42180.1 - 2.1e-16 59.4 0.1 1.9e-15 56.3 0.0 2.3 2 0 0 2 2 2 1 PAZ domain DUF1785 PF08699.5 KFH42180.1 - 8.1e-15 53.9 0.1 1.7e-14 52.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PhrC_PhrF PF11131.3 KFH42181.1 - 0.23 11.0 1.8 0.24 11.0 0.1 1.8 2 0 0 2 2 2 0 Rap-phr extracellular signalling DUF3659 PF12396.3 KFH42182.1 - 1.8e-18 65.9 3.0 2.1e-12 46.4 0.2 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF3659) AflR PF08493.5 KFH42182.1 - 0.56 9.1 6.3 0.027 13.5 0.5 1.7 2 0 0 2 2 2 0 Aflatoxin regulatory protein G-patch PF01585.18 KFH42183.1 - 2.8e-05 23.8 0.1 5.2e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 G-patch domain U1snRNP70_N PF12220.3 KFH42183.1 - 0.038 14.3 0.8 0.087 13.1 0.5 1.6 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal zf-Di19 PF05605.7 KFH42183.1 - 0.045 13.8 0.4 0.081 13.0 0.3 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF2027 PF09640.5 KFH42183.1 - 0.2 10.9 0.3 0.31 10.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2027) NIPSNAP PF07978.8 KFH42184.1 - 1.4e-36 124.5 7.2 5e-29 100.2 0.1 2.7 3 0 0 3 3 3 2 NIPSNAP GST_N_2 PF13409.1 KFH42185.1 - 1.5e-22 79.3 0.0 3.4e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFH42185.1 - 3.7e-15 55.5 0.1 9.1e-15 54.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KFH42185.1 - 3.5e-05 23.9 0.0 0.037 14.2 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFH42185.1 - 0.0016 18.3 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFH42185.1 - 0.01 16.2 0.0 0.022 15.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AJAP1_PANP_C PF15298.1 KFH42186.1 - 0.25 11.2 9.6 0.27 11.0 6.6 1.1 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Mucin PF01456.12 KFH42186.1 - 0.98 9.1 21.3 1.2 8.9 14.7 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein FKBP_C PF00254.23 KFH42187.1 - 4.2e-15 55.5 0.1 4.9e-15 55.3 0.1 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Sec1 PF00995.18 KFH42190.1 - 2.4e-139 465.5 0.0 2.7e-139 465.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Apo-CIII PF05778.7 KFH42190.1 - 0.18 11.2 0.1 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) MLANA PF14991.1 KFH42191.1 - 0.011 15.6 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 Protein melan-A TMEM51 PF15345.1 KFH42191.1 - 0.019 14.6 0.0 0.026 14.2 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 SKG6 PF08693.5 KFH42191.1 - 0.03 13.6 0.1 0.067 12.5 0.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Molybdop_Fe4S4 PF04879.11 KFH42191.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin oxidoreductase Fe4S4 domain AA_permease PF00324.16 KFH42193.1 - 3.6e-118 394.9 45.2 4.4e-118 394.6 31.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFH42193.1 - 5e-33 114.2 49.9 7e-33 113.7 34.6 1.2 1 0 0 1 1 1 1 Amino acid permease DUF3333 PF11812.3 KFH42193.1 - 2.1 8.3 0.0 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3333) RRM_6 PF14259.1 KFH42194.1 - 2.1e-07 30.8 0.0 7.3e-07 29.0 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFH42194.1 - 1.5e-06 27.7 0.0 0.00022 20.8 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH42194.1 - 0.0014 18.4 0.0 0.017 14.9 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAR2 PF05282.6 KFH42194.1 - 0.5 9.2 8.0 0.022 13.6 1.3 1.7 2 0 0 2 2 2 0 AAR2 protein Aa_trans PF01490.13 KFH42195.1 - 8.1e-88 294.6 15.9 1.2e-87 294.0 11.0 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein YfhO PF09586.5 KFH42195.1 - 1.1 7.2 11.2 0.017 13.2 2.9 1.5 2 0 0 2 2 2 0 Bacterial membrane protein YfhO Abhydrolase_9_N PF15420.1 KFH42195.1 - 2.3 7.8 11.8 0.42 10.3 2.7 3.0 3 0 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus SH3_1 PF00018.23 KFH42196.1 - 8.9e-10 37.8 0.8 8.2e-09 34.7 0.0 2.2 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 KFH42196.1 - 7.9e-08 31.6 0.1 2.5e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 KFH42196.1 - 6.4e-06 25.6 0.0 6.4e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain DUF4389 PF14333.1 KFH42196.1 - 0.12 12.1 3.5 0.16 11.7 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) Exo5 PF09810.4 KFH42197.1 - 4.2e-108 361.3 0.0 5e-108 361.1 0.0 1.0 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease FoP_duplication PF13865.1 KFH42197.1 - 0.87 10.0 0.0 0.87 10.0 0.0 3.0 4 1 0 4 4 4 0 C-terminal duplication domain of Friend of PRMT1 ThiF PF00899.16 KFH42198.1 - 1.2e-49 167.6 0.0 8.7e-31 106.5 0.0 2.6 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 KFH42198.1 - 2.6e-38 129.4 4.4 4.1e-26 90.3 0.0 3.0 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 KFH42198.1 - 7.5e-34 116.5 0.1 2.2e-33 115.0 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 KFH42198.1 - 1.9e-25 87.9 1.9 3.3e-20 71.2 0.2 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Rogdi_lz PF10259.4 KFH42200.1 - 1.9e-62 210.8 0.0 2.2e-62 210.6 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein DUF3669 PF12417.3 KFH42201.1 - 1.1e-08 34.6 0.0 2.1e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Zinc finger protein Lyase_1 PF00206.15 KFH42202.1 - 2.6e-86 289.6 0.0 3.5e-86 289.2 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 KFH42202.1 - 1.7e-25 88.8 0.1 3.1e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal FSH1 PF03959.8 KFH42204.1 - 6.4e-60 202.2 0.0 8.2e-60 201.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KFH42204.1 - 4.1e-06 26.6 0.0 5.4e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFH42204.1 - 4e-05 23.6 4.5 0.0098 15.7 3.1 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.6 KFH42204.1 - 0.0084 15.5 0.0 0.085 12.2 0.0 2.2 2 0 0 2 2 2 1 PE-PPE domain Abhydrolase_1 PF00561.15 KFH42204.1 - 0.057 12.9 0.4 1.8 8.0 0.1 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Esterase_phd PF10503.4 KFH42204.1 - 0.06 12.5 3.1 0.67 9.1 0.9 2.4 3 0 0 3 3 3 0 Esterase PHB depolymerase ATP-synt_J PF04911.7 KFH42205.1 - 2.9e-23 81.0 0.3 2.9e-23 81.0 0.2 1.8 2 0 0 2 2 2 1 ATP synthase j chain zf-MYND PF01753.13 KFH42206.1 - 4.2e-05 23.3 9.9 0.00011 21.9 6.8 1.7 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KFH42206.1 - 9.5e-05 22.1 4.0 0.0002 21.1 2.8 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Glyco_hydro_92 PF07971.7 KFH42207.1 - 1.7e-150 502.0 1.0 2.2e-150 501.6 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Filament PF00038.16 KFH42208.1 - 0.00013 21.5 12.2 0.00022 20.8 8.2 1.6 1 1 0 1 1 1 1 Intermediate filament protein CENP-Q PF13094.1 KFH42208.1 - 0.0013 18.7 3.1 0.0027 17.7 2.1 1.5 1 1 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit TMF_TATA_bd PF12325.3 KFH42208.1 - 0.0057 16.3 7.6 0.0057 16.3 5.3 2.9 1 1 2 3 3 3 1 TATA element modulatory factor 1 TATA binding COG5 PF10392.4 KFH42208.1 - 0.02 14.8 0.6 1.1 9.2 0.0 2.3 1 1 1 2 2 2 0 Golgi transport complex subunit 5 ORF6C PF10552.4 KFH42208.1 - 0.028 14.1 3.5 0.18 11.5 0.0 2.4 1 1 0 2 2 2 0 ORF6C domain Prominin PF05478.6 KFH42208.1 - 0.038 11.5 3.0 0.037 11.5 1.0 1.7 2 0 0 2 2 2 0 Prominin Synaptobrevin PF00957.16 KFH42208.1 - 0.061 12.9 0.4 9.8 5.8 0.2 2.5 2 1 0 2 2 2 0 Synaptobrevin ER PF01133.12 KFH42208.1 - 0.12 12.0 1.4 0.25 11.0 0.9 1.5 1 0 0 1 1 1 0 Enhancer of rudimentary IncA PF04156.9 KFH42208.1 - 0.27 10.7 16.5 17 4.9 11.4 2.4 1 1 0 1 1 1 0 IncA protein LTXXQ PF07813.7 KFH42208.1 - 0.36 11.3 3.9 1 9.8 0.9 2.5 2 1 1 3 3 2 0 LTXXQ motif family protein V_ATPase_I PF01496.14 KFH42208.1 - 0.76 7.5 9.6 0.23 9.2 4.3 1.6 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF2205 PF10224.4 KFH42208.1 - 0.89 9.1 9.2 0.082 12.4 2.7 2.1 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) BLOC1_2 PF10046.4 KFH42208.1 - 1.3 9.2 7.7 12 6.0 0.0 3.1 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ADIP PF11559.3 KFH42208.1 - 1.5 8.7 10.0 7.2 6.4 3.6 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1515 PF07439.6 KFH42208.1 - 1.6 8.5 5.1 2.7 7.8 1.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Ima1_N PF09779.4 KFH42208.1 - 1.7 9.1 8.1 1.5 9.3 2.0 2.9 2 1 1 3 3 3 0 Ima1 N-terminal domain Fzo_mitofusin PF04799.8 KFH42208.1 - 2 7.7 6.4 4.9 6.4 1.3 2.4 1 1 1 2 2 2 0 fzo-like conserved region Spectrin PF00435.16 KFH42208.1 - 2.3 8.5 11.0 6 7.2 2.6 3.2 1 1 2 3 3 3 0 Spectrin repeat PspB PF06667.7 KFH42208.1 - 2.3 8.2 9.9 0.77 9.7 0.2 3.6 3 1 2 5 5 5 0 Phage shock protein B Med9 PF07544.8 KFH42208.1 - 2.3 8.0 9.2 0.48 10.1 0.3 3.0 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF342 PF03961.8 KFH42208.1 - 2.9 6.2 9.0 9.8 4.4 6.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Troponin PF00992.15 KFH42208.1 - 4 7.5 18.7 5.4 7.0 0.3 2.4 2 1 0 2 2 2 0 Troponin TPR_MLP1_2 PF07926.7 KFH42208.1 - 4 7.1 15.5 2.8 7.6 6.8 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4404 PF14357.1 KFH42208.1 - 5.8 7.4 7.6 17 5.9 0.2 2.9 2 2 0 2 2 2 0 Domain of unknown function (DUF4404) TMCO5 PF14992.1 KFH42208.1 - 5.9 5.9 16.4 1.5 7.9 0.7 2.1 2 0 0 2 2 2 0 TMCO5 family APG6 PF04111.7 KFH42208.1 - 8 5.4 17.3 0.76 8.7 7.0 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 FliJ PF02050.11 KFH42208.1 - 8.1 6.5 14.4 13 5.8 4.6 2.5 1 1 1 2 2 2 0 Flagellar FliJ protein Glyco_hydro_7 PF00840.15 KFH42209.1 - 2e-145 484.4 5.7 2.4e-145 484.2 4.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DASH_Spc19 PF08287.6 KFH42210.1 - 6.4e-36 123.2 7.7 1.3e-35 122.2 5.3 1.5 1 1 0 1 1 1 1 Spc19 DUF4398 PF14346.1 KFH42210.1 - 0.87 9.6 10.4 3.6 7.7 7.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4398) Aldedh PF00171.17 KFH42211.1 - 1.3e-136 455.6 0.0 1.6e-136 455.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KFH42211.1 - 6e-05 21.9 0.0 0.00018 20.3 0.0 1.9 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 KFH42211.1 - 0.047 12.9 0.0 8.1 5.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) PCI PF01399.22 KFH42212.1 - 1.1e-21 77.0 0.0 7e-21 74.5 0.0 2.4 2 0 0 2 2 2 1 PCI domain YjeF_N PF03853.10 KFH42213.1 - 2.9e-33 114.8 0.0 3.5e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus NMD3 PF04981.8 KFH42214.1 - 1.7e-68 230.2 1.0 3.1e-68 229.4 0.7 1.4 1 0 0 1 1 1 1 NMD3 family DUF35_N PF12172.3 KFH42214.1 - 0.27 11.1 4.7 1.3 9.0 0.0 2.8 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DZR PF12773.2 KFH42214.1 - 1.8 8.4 9.7 14 5.5 4.0 2.8 2 1 0 2 2 2 0 Double zinc ribbon Ribosomal_S16 PF00886.14 KFH42215.1 - 2.1e-23 81.8 0.5 5.7e-23 80.3 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S16 Methyltransf_18 PF12847.2 KFH42216.1 - 1.9e-10 41.3 0.0 3e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFH42216.1 - 8.9e-09 35.6 0.0 1.5e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH42216.1 - 1.9e-08 34.6 0.0 3.1e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFH42216.1 - 1.3e-07 31.6 0.2 2.6e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH42216.1 - 1.4e-06 28.6 0.0 2.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH42216.1 - 6.3e-06 25.9 0.0 8.3e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH42216.1 - 0.00033 20.2 0.0 0.00041 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KFH42216.1 - 0.00034 19.8 0.0 0.00046 19.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.9 KFH42216.1 - 0.0048 16.2 0.0 0.0082 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.12 KFH42216.1 - 0.034 13.1 0.0 0.05 12.5 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family CheR PF01739.13 KFH42216.1 - 0.066 12.4 0.0 0.23 10.6 0.0 1.8 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Mac PF12464.3 KFH42216.1 - 0.08 12.9 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Maltose acetyltransferase Phasin_2 PF09361.5 KFH42216.1 - 0.14 12.2 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Phasin protein DUF4140 PF13600.1 KFH42217.1 - 0.98 9.9 7.0 18 5.8 0.5 3.0 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) PPR_2 PF13041.1 KFH42218.1 - 7.5e-46 153.8 8.3 1.5e-09 37.7 0.0 15.0 11 4 5 16 16 16 8 PPR repeat family PPR PF01535.15 KFH42218.1 - 3.7e-30 101.7 22.6 0.00024 20.8 0.0 15.4 20 0 0 20 20 20 6 PPR repeat PPR_3 PF13812.1 KFH42218.1 - 7.6e-27 91.3 21.9 1e-05 25.4 0.0 15.5 19 0 0 19 19 19 5 Pentatricopeptide repeat domain PPR_1 PF12854.2 KFH42218.1 - 2.4e-24 84.4 0.1 4.7e-08 32.3 0.0 10.0 9 0 0 9 9 9 4 PPR repeat RPM2 PF08579.6 KFH42218.1 - 4.2e-05 23.6 0.0 0.014 15.5 0.0 3.8 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_7 PF13176.1 KFH42218.1 - 0.016 14.9 0.1 4.9 7.1 0.0 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ATP13 PF12921.2 KFH42218.1 - 0.15 11.4 0.3 9.1 5.6 0.0 3.4 3 0 0 3 3 3 0 Mitochondrial ATPase expression Esterase_phd PF10503.4 KFH42219.1 - 2.3e-05 23.7 0.0 9.3e-05 21.7 0.0 1.9 2 0 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 KFH42219.1 - 2.7e-05 23.9 0.0 0.00011 21.9 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFH42219.1 - 0.00018 21.4 0.1 0.0096 15.8 0.0 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KFH42219.1 - 0.013 14.9 0.0 0.03 13.7 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 KFH42219.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF382 PF04037.8 KFH42221.1 - 1.1e-61 206.2 0.5 1.1e-61 206.2 0.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.11 KFH42221.1 - 2.8e-20 71.4 6.0 5.7e-20 70.4 4.1 1.6 1 0 0 1 1 1 1 PSP MPC PF03650.8 KFH42223.1 - 2.7e-35 120.9 0.0 3.3e-35 120.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) MtN3_slv PF03083.11 KFH42223.1 - 0.12 12.3 0.1 0.15 11.9 0.1 1.1 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange PAPA-1 PF04795.7 KFH42224.1 - 2.1e-26 92.4 3.9 2.1e-26 92.4 2.7 3.1 3 1 0 3 3 3 1 PAPA-1-like conserved region Hist_deacetyl PF00850.14 KFH42225.1 - 2.9e-90 302.7 0.0 5.1e-90 301.9 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 KFH42225.1 - 6.2e-42 143.0 0.1 9.1e-42 142.4 0.1 1.2 1 0 0 1 1 1 1 Arb2 domain DBR1 PF05011.8 KFH42226.1 - 9.4e-27 93.6 0.0 1.4e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 KFH42226.1 - 0.00045 19.6 2.3 0.0011 18.3 1.6 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase TPT PF03151.11 KFH42227.1 - 1.3e-38 132.0 2.8 1.3e-38 132.0 1.9 1.7 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KFH42227.1 - 3e-08 32.9 11.0 8.7e-08 31.4 7.6 1.7 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KFH42227.1 - 6.3e-08 32.7 24.4 0.00023 21.2 6.8 3.0 2 1 0 2 2 2 2 EamA-like transporter family DUF378 PF04070.7 KFH42229.1 - 0.032 13.8 0.3 0.06 12.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF378) Glyco_transf_20 PF00982.16 KFH42230.1 - 7.7e-150 499.4 0.0 1e-149 499.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KFH42230.1 - 2.4e-77 258.9 0.0 4.5e-77 258.1 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase Baculo_DNA_bind PF04786.7 KFH42230.1 - 0.00045 19.4 0.0 0.14 11.2 0.0 2.3 2 0 0 2 2 2 2 ssDNA binding protein SAB PF04382.8 KFH42231.1 - 0.08 12.6 0.1 6 6.6 0.1 2.9 2 0 0 2 2 2 0 SAB domain F-box-like PF12937.2 KFH42233.1 - 1.4e-07 31.0 0.1 3.9e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFH42233.1 - 6.1e-05 22.5 0.1 0.00016 21.2 0.1 1.7 1 0 0 1 1 1 1 F-box domain Ras PF00071.17 KFH42234.1 - 2.5e-63 212.3 0.2 3e-63 212.0 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFH42234.1 - 1e-21 77.6 0.1 1.4e-21 77.1 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFH42234.1 - 3.5e-13 49.1 0.1 4.5e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFH42234.1 - 2.3e-08 34.0 0.1 3.5e-08 33.3 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFH42234.1 - 3.3e-05 23.4 0.1 0.00016 21.1 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KFH42234.1 - 9.1e-05 22.6 0.1 0.00024 21.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 KFH42234.1 - 9.1e-05 21.7 0.1 0.00015 20.9 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_15 PF13175.1 KFH42234.1 - 0.001 18.1 0.0 0.0012 17.9 0.0 1.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 KFH42234.1 - 0.0015 18.4 0.1 0.0034 17.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KFH42234.1 - 0.0019 17.3 0.1 0.0045 16.1 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SpoIIID PF12116.3 KFH42234.1 - 0.0039 17.1 0.1 0.095 12.6 0.0 2.2 2 0 0 2 2 2 1 Stage III sporulation protein D AAA_24 PF13479.1 KFH42234.1 - 0.012 15.1 0.1 0.037 13.5 0.0 1.7 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.22 KFH42234.1 - 0.014 15.6 0.1 0.021 15.1 0.1 1.4 1 1 0 1 1 1 0 ABC transporter SRPRB PF09439.5 KFH42234.1 - 0.017 14.3 0.0 0.035 13.3 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 KFH42234.1 - 0.026 13.8 0.1 0.068 12.4 0.0 1.7 2 1 1 3 3 3 0 Ferrous iron transport protein B AAA_16 PF13191.1 KFH42234.1 - 0.038 13.9 0.4 0.079 12.9 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 KFH42234.1 - 0.096 12.2 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 KFH42234.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Chromo PF00385.19 KFH42235.1 - 7.1e-08 32.0 0.1 2.5e-07 30.2 0.0 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Varsurf_PPLC PF03490.8 KFH42237.1 - 0.12 12.0 0.0 0.38 10.4 0.0 1.8 2 0 0 2 2 2 0 Variant-surface-glycoprotein phospholipase C Epimerase PF01370.16 KFH42238.1 - 2.2e-17 63.2 0.0 3.2e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFH42238.1 - 1.9e-10 41.0 0.0 3.6e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KFH42238.1 - 6.8e-06 25.5 0.0 3.4e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 KFH42238.1 - 2.4e-05 24.3 0.1 5.3e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 KFH42238.1 - 0.00051 19.0 0.0 0.041 12.7 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain 3Beta_HSD PF01073.14 KFH42238.1 - 0.027 13.1 0.0 1.9 7.0 0.0 2.1 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF3693 PF12472.3 KFH42239.1 - 0.05 13.1 0.1 0.072 12.7 0.1 1.2 1 0 0 1 1 1 0 Phage related protein CFEM PF05730.6 KFH42240.1 - 8.4e-08 31.9 6.1 1.7e-07 30.9 4.2 1.5 1 0 0 1 1 1 1 CFEM domain DUF4131 PF13567.1 KFH42240.1 - 1.6 8.1 9.0 1 8.7 3.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) PHD PF00628.24 KFH42241.1 - 0.00025 20.6 3.4 0.00054 19.5 2.4 1.6 1 0 0 1 1 1 1 PHD-finger VEFS-Box PF09733.4 KFH42241.1 - 0.0045 16.6 0.0 0.0079 15.8 0.0 1.4 1 0 0 1 1 1 1 VEFS-Box of polycomb protein zf-RING-like PF08746.6 KFH42241.1 - 0.46 10.5 3.9 1.4 8.9 2.8 1.9 1 1 0 1 1 1 0 RING-like domain Cut8_N PF14482.1 KFH42241.1 - 3.3 7.8 9.9 0.069 13.1 0.8 2.8 3 0 0 3 3 3 0 Cut8 proteasome-binding domain AA_permease_2 PF13520.1 KFH42242.1 - 9.1e-72 241.9 37.6 1.2e-71 241.5 26.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFH42242.1 - 4.9e-20 71.3 35.8 4.2e-19 68.2 24.8 2.0 1 1 0 1 1 1 1 Amino acid permease Aa_trans PF01490.13 KFH42242.1 - 0.0014 17.1 13.3 0.0014 17.1 9.2 2.0 2 1 0 2 2 2 1 Transmembrane amino acid transporter protein Pex14_N PF04695.8 KFH42243.1 - 3.8e-20 72.3 0.2 5.8e-20 71.7 0.1 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase PF00069.20 KFH42244.1 - 1.4e-25 89.9 0.0 6.3e-25 87.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH42244.1 - 1.4e-06 27.5 0.2 8e-05 21.8 0.0 3.1 2 2 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KFH42244.1 - 7.4e-05 22.5 0.6 0.0072 16.0 0.1 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KFH42244.1 - 0.1 11.5 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like ORC5_C PF14630.1 KFH42246.1 - 7.2e-77 258.4 0.0 9.4e-77 258.0 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 KFH42246.1 - 9.9e-13 48.4 0.3 3.6e-12 46.6 0.1 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KFH42246.1 - 0.16 12.1 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain zf-LITAF-like PF10601.4 KFH42247.1 - 4.7e-11 42.3 9.1 6.3e-11 41.9 6.3 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Cys_rich_KTR PF14205.1 KFH42247.1 - 0.0037 16.6 3.5 0.1 12.1 1.1 2.4 2 1 0 2 2 2 2 Cysteine-rich KTR Sgf11 PF08209.6 KFH42247.1 - 0.13 11.6 1.0 3.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Zn_clus PF00172.13 KFH42248.1 - 4.6e-09 36.0 9.6 7.2e-09 35.4 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFH42248.1 - 3.3e-06 26.1 0.1 7.9e-06 24.9 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 KFH42250.1 - 1.2e-130 436.1 32.5 1.4e-130 435.9 22.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH42250.1 - 9.6e-22 77.1 38.0 2.6e-14 52.7 11.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Brix PF04427.13 KFH42251.1 - 2.4e-39 134.9 0.0 3.2e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 Brix domain DUF716 PF04819.7 KFH42252.1 - 0.017 14.5 0.6 0.019 14.4 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF716) DUF1148 PF06618.6 KFH42252.1 - 0.11 12.4 0.1 0.12 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1148) FleQ PF06490.6 KFH42254.1 - 0.02 15.0 0.0 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 Flagellar regulatory protein FleQ BUD22 PF09073.5 KFH42254.1 - 1.1 8.3 9.8 1.5 7.7 6.8 1.1 1 0 0 1 1 1 0 BUD22 GTP_EFTU PF00009.22 KFH42255.1 - 8.3e-50 168.8 0.0 1.4e-49 168.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 KFH42255.1 - 2.6e-19 69.1 0.2 5.7e-19 68.0 0.2 1.5 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D2 PF03144.20 KFH42255.1 - 3.4e-09 36.6 1.8 7.2e-09 35.6 0.1 2.5 3 0 0 3 3 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.12 KFH42255.1 - 8.4e-09 35.5 0.0 2.2e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 KFH42255.1 - 3.5e-08 33.4 0.1 1.2e-07 31.6 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 KFH42255.1 - 0.00029 20.3 0.1 0.00061 19.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 KFH42255.1 - 0.0014 19.1 0.1 0.015 15.8 0.0 2.3 1 1 0 1 1 1 1 Miro-like protein Ras PF00071.17 KFH42255.1 - 0.0042 16.4 0.1 0.22 10.8 0.0 2.5 1 1 1 2 2 2 1 Ras family Septin PF00735.13 KFH42255.1 - 0.012 14.6 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Septin Arf PF00025.16 KFH42255.1 - 0.022 14.0 0.0 3.7 6.7 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family SRPRB PF09439.5 KFH42255.1 - 0.027 13.6 0.0 1.5 8.0 0.0 2.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 KFH42255.1 - 0.052 13.3 0.1 1.6 8.5 0.0 2.5 1 1 1 2 2 2 0 Dynamin family MobB PF03205.9 KFH42255.1 - 0.087 12.5 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FeoB_N PF02421.13 KFH42255.1 - 0.11 11.7 0.1 1.6 7.9 0.0 2.4 2 1 0 2 2 2 0 Ferrous iron transport protein B TLP-20 PF06088.6 KFH42255.1 - 5.7 6.5 5.7 24 4.5 1.7 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Pyridox_oxidase PF01243.15 KFH42256.1 - 2.8e-07 30.4 0.0 0.00082 19.3 0.0 2.4 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.19 KFH42256.1 - 0.011 15.7 0.0 0.096 12.8 0.0 2.2 1 1 0 1 1 1 0 Oxidoreductase FAD-binding domain CTP_transf_2 PF01467.21 KFH42257.1 - 3.4e-28 98.6 0.0 4.4e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase DUF4237 PF14021.1 KFH42257.1 - 0.13 12.5 0.0 0.62 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4237) Cpn60_TCP1 PF00118.19 KFH42258.1 - 9.3e-149 496.1 1.8 1.1e-148 495.9 1.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ArfGap PF01412.13 KFH42261.1 - 1e-39 134.8 0.5 2.1e-39 133.9 0.3 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UBA PF00627.26 KFH42261.1 - 1e-05 25.1 0.0 2.4e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Glyco_hydro_72 PF03198.9 KFH42262.1 - 4.1e-122 407.0 0.3 5e-122 406.7 0.2 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 KFH42262.1 - 2.6e-05 23.5 0.2 0.00045 19.5 0.1 2.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TilS PF09179.6 KFH42263.1 - 0.16 12.0 0.0 0.44 10.6 0.0 1.8 1 0 0 1 1 1 0 TilS substrate binding domain Tbf5 PF06331.7 KFH42264.1 - 4.8e-28 96.7 0.5 5.1e-28 96.6 0.3 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 DUF2461 PF09365.5 KFH42266.1 - 1.2e-61 207.7 1.1 8e-61 205.1 0.8 2.1 1 1 0 1 1 1 1 Conserved hypothetical protein (DUF2461) Daxx PF03344.10 KFH42266.1 - 0.038 12.4 7.5 0.047 12.1 5.2 1.1 1 0 0 1 1 1 0 Daxx Family PPP4R2 PF09184.6 KFH42266.1 - 0.088 12.3 9.9 0.17 11.4 6.9 1.4 1 0 0 1 1 1 0 PPP4R2 HSP70 PF00012.15 KFH42267.1 - 9.4e-270 895.7 12.8 1.1e-269 895.5 8.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFH42267.1 - 1.3e-18 66.7 1.4 1.3e-16 60.1 0.3 2.3 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.13 KFH42267.1 - 0.0023 17.0 2.0 0.19 10.7 0.1 3.2 2 1 1 3 3 3 1 Hydantoinase/oxoprolinase StbA PF06406.6 KFH42267.1 - 0.02 13.8 2.0 0.15 10.9 0.0 2.5 3 0 0 3 3 3 0 StbA protein FtsA PF14450.1 KFH42267.1 - 0.028 14.2 7.0 0.75 9.6 0.8 3.4 2 2 0 2 2 2 0 Cell division protein FtsA DUF202 PF02656.10 KFH42268.1 - 0.54 10.5 3.6 5.4 7.3 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF202) ECH PF00378.15 KFH42269.1 - 2.5e-39 134.8 0.1 4.4e-39 134.0 0.1 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Exo_endo_phos PF03372.18 KFH42270.1 - 5.2e-13 49.4 0.1 8.4e-13 48.8 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MFS_1 PF07690.11 KFH42271.1 - 3.2e-10 39.2 57.0 4.6e-09 35.4 37.9 3.2 1 1 0 1 1 1 1 Major Facilitator Superfamily RTA1 PF04479.8 KFH42272.1 - 4.1e-35 121.2 5.3 4.1e-35 121.2 3.6 1.3 1 1 0 1 1 1 1 RTA1 like protein DUF3154 PF11351.3 KFH42272.1 - 0.046 13.4 1.8 0.093 12.4 0.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3154) zf-CHY PF05495.7 KFH42273.1 - 2.1e-15 56.5 25.1 9.7e-15 54.4 10.1 3.2 3 0 0 3 3 3 2 CHY zinc finger Mu-like_Com PF10122.4 KFH42273.1 - 0.00053 18.9 0.2 0.00053 18.9 0.1 2.7 3 0 0 3 3 3 1 Mu-like prophage protein Com RWD PF05773.17 KFH42273.1 - 0.0085 15.9 0.0 0.031 14.1 0.0 1.9 2 0 0 2 2 2 1 RWD domain Phage_T7_Capsid PF05396.6 KFH42273.1 - 0.048 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Phage T7 capsid assembly protein DUF3295 PF11702.3 KFH42274.1 - 2.2e-131 439.3 36.0 2.7e-131 439.0 24.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 KFH42274.1 - 6.6e-13 47.9 0.5 1.2e-12 47.1 0.4 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Glyco_transf_90 PF05686.7 KFH42275.1 - 4.8e-18 65.0 0.0 2.6e-15 56.0 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 90 Oxysterol_BP PF01237.13 KFH42276.1 - 3.5e-106 354.6 0.0 9.9e-106 353.1 0.0 1.7 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 KFH42276.1 - 9.1e-38 128.2 0.4 3.4e-37 126.4 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 KFH42276.1 - 8.2e-05 22.7 0.0 0.00023 21.3 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFH42276.1 - 0.0038 17.4 0.9 0.065 13.4 0.6 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain GOLD_2 PF13897.1 KFH42276.1 - 0.19 11.9 1.0 0.47 10.6 0.0 2.1 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking TMEM154 PF15102.1 KFH42278.1 - 0.013 15.1 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family ATP-synt_ab PF00006.20 KFH42279.1 - 1.7e-70 236.8 0.0 2.5e-70 236.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KFH42279.1 - 8.7e-28 97.0 0.0 2.3e-27 95.6 0.0 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KFH42279.1 - 8.9e-12 45.0 0.7 2.6e-11 43.5 0.5 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 KFH42279.1 - 0.013 15.4 0.5 0.044 13.6 0.2 2.1 2 0 0 2 2 2 0 HAS barrel domain Arch_ATPase PF01637.13 KFH42279.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase RNase_PH PF01138.16 KFH42281.1 - 2.4e-13 50.5 0.1 7e-13 49.0 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KFH42281.1 - 0.014 15.3 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 PITH PF06201.8 KFH42282.1 - 7.6e-39 132.9 0.0 1e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 KFH42282.1 - 6.6e-28 96.4 0.0 1e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KFH42282.1 - 2.1e-07 30.9 0.0 3.2e-06 27.1 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KFH42282.1 - 6.5e-06 26.3 0.0 2e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 KFH42282.1 - 0.0014 18.2 0.1 0.0098 15.4 0.0 2.0 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.16 KFH42282.1 - 0.003 17.2 0.0 0.03 13.9 0.0 2.2 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_7 PF13899.1 KFH42282.1 - 0.024 14.6 0.0 0.058 13.4 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.1 KFH42282.1 - 0.081 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin HyaE PF07449.6 KFH42282.1 - 0.084 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DUF4066 PF13278.1 KFH42283.1 - 2.1e-13 49.9 0.0 2.5e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KFH42283.1 - 1.1e-05 24.8 0.0 1.7e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Fungal_trans PF04082.13 KFH42284.1 - 1.3e-05 24.1 0.1 2.4e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH42284.1 - 0.0014 18.5 12.4 0.0026 17.6 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WLM PF08325.5 KFH42286.1 - 1e-49 168.9 0.1 1.9e-49 168.0 0.0 1.4 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 KFH42286.1 - 3.5e-07 30.2 1.1 3.5e-07 30.2 0.8 1.7 2 0 0 2 2 2 1 Protein of unknown function DUF45 CHGN PF05679.11 KFH42286.1 - 0.13 10.9 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Chondroitin N-acetylgalactosaminyltransferase BTB PF00651.26 KFH42287.1 - 6.6e-08 32.5 0.0 1.6e-07 31.3 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain Homeobox PF00046.24 KFH42288.1 - 8.2e-14 50.9 5.1 1.6e-13 50.0 3.5 1.5 1 0 0 1 1 1 1 Homeobox domain EF-1_beta_acid PF10587.4 KFH42288.1 - 0.28 11.3 3.8 0.59 10.3 2.7 1.5 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region RepB-RCR_reg PF10723.4 KFH42288.1 - 0.42 10.3 2.4 12 5.6 1.1 2.7 2 1 0 2 2 2 0 Replication regulatory protein RepB Pkinase PF00069.20 KFH42289.1 - 2.8e-24 85.6 0.3 3.3e-19 69.0 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFH42289.1 - 2.9e-09 36.3 0.0 6.6e-09 35.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH42289.1 - 0.0035 16.3 0.0 0.006 15.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFH42289.1 - 0.0037 17.0 0.0 0.0092 15.7 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF3818 PF12825.2 KFH42289.1 - 0.037 12.7 0.1 0.065 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) Pox_ser-thr_kin PF05445.6 KFH42289.1 - 0.041 12.6 0.1 0.065 12.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Metal_resist PF13801.1 KFH42289.1 - 0.048 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Heavy-metal resistance RepC PF06504.6 KFH42289.1 - 0.049 12.5 0.0 0.078 11.9 0.0 1.2 1 0 0 1 1 1 0 Replication protein C (RepC) Exo_endo_phos PF03372.18 KFH42290.1 - 1.7e-20 74.0 1.6 1.7e-20 74.0 1.1 1.5 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Spo7 PF03907.8 KFH42290.1 - 0.15 11.6 0.2 0.25 10.9 0.1 1.2 1 0 0 1 1 1 0 Spo7-like protein GRASP55_65 PF04495.9 KFH42291.1 - 4.2e-06 26.7 0.0 8.2e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 KFH42291.1 - 1.6e-05 24.7 0.0 2.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 KFH42291.1 - 0.001 19.2 0.0 0.0021 18.1 0.0 1.5 1 1 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) DUF3336 PF11815.3 KFH42291.1 - 0.12 11.9 0.1 0.57 9.6 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3336) tRNA-synt_2 PF00152.15 KFH42292.1 - 1.8e-68 230.7 0.0 3.1e-68 230.0 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KFH42292.1 - 0.0068 16.2 0.0 0.018 14.8 0.0 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Fungal_trans_2 PF11951.3 KFH42293.1 - 0.00018 20.2 0.1 0.0016 17.1 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain GOLGA2L5 PF15070.1 KFH42294.1 - 0.0027 16.2 0.9 0.0027 16.2 0.6 1.5 2 0 0 2 2 2 1 Putative golgin subfamily A member 2-like protein 5 PspA_IM30 PF04012.7 KFH42294.1 - 0.0067 15.8 1.1 0.0067 15.8 0.8 1.8 2 0 0 2 2 2 1 PspA/IM30 family DUF3450 PF11932.3 KFH42294.1 - 0.012 14.8 5.4 0.019 14.2 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Uds1 PF15456.1 KFH42294.1 - 0.022 14.7 1.4 0.047 13.6 0.0 2.0 2 1 1 3 3 3 0 Up-regulated During Septation IncA PF04156.9 KFH42294.1 - 5.1 6.6 6.6 0.46 10.0 0.4 1.9 2 0 0 2 2 2 0 IncA protein CENP-K PF11802.3 KFH42295.1 - 7.2e-09 35.2 1.9 7.7e-05 22.0 0.8 2.7 3 0 0 3 3 3 2 Centromere-associated protein K FhuF PF06276.7 KFH42295.1 - 0.14 12.0 0.9 17 5.3 0.1 2.8 2 1 0 2 2 2 0 Ferric iron reductase FhuF-like transporter Cep57_CLD_2 PF14197.1 KFH42295.1 - 0.2 11.6 0.2 0.2 11.6 0.1 3.8 4 0 0 4 4 4 0 Centrosome localisation domain of PPC89 Mnd1 PF03962.10 KFH42295.1 - 1.5 8.4 13.8 2 8.0 3.0 2.9 3 0 0 3 3 3 0 Mnd1 family DUF1690 PF07956.6 KFH42295.1 - 2.6 8.0 9.9 0.67 9.9 2.1 2.6 3 0 0 3 3 3 0 Protein of Unknown function (DUF1690) Spectrin PF00435.16 KFH42295.1 - 8.2 6.7 10.5 0.81 10.0 0.4 3.2 3 1 0 3 3 3 0 Spectrin repeat RabGAP-TBC PF00566.13 KFH42296.1 - 6.6e-33 113.9 0.0 1.6e-32 112.7 0.0 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Ribosomal_L5 PF00281.14 KFH42297.1 - 9.3e-22 76.5 0.0 5.4e-21 74.1 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L5 Ribosomal_L5_C PF00673.16 KFH42297.1 - 9.2e-20 70.1 0.1 3.2e-18 65.2 0.0 2.2 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Carb_kinase PF01256.12 KFH42298.1 - 2.9e-55 187.1 0.1 3.9e-55 186.7 0.1 1.2 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 KFH42298.1 - 0.012 14.7 0.5 0.036 13.2 0.3 1.7 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase PTPA PF03095.10 KFH42299.1 - 4.3e-106 354.4 0.0 5e-106 354.2 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Glyco_trans_2_3 PF13632.1 KFH42300.1 - 7.9e-16 58.3 0.9 7.9e-16 58.3 0.6 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KFH42300.1 - 1.1e-06 28.6 0.0 2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 NAD_kinase PF01513.16 KFH42301.1 - 2e-70 236.8 0.0 2.5e-70 236.4 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Clr5 PF14420.1 KFH42302.1 - 1.3e-18 66.5 3.1 3e-18 65.4 2.2 1.6 1 0 0 1 1 1 1 Clr5 domain Mac PF12464.3 KFH42302.1 - 0.01 15.8 0.2 0.032 14.2 0.2 1.9 1 0 0 1 1 1 0 Maltose acetyltransferase TPR_14 PF13428.1 KFH42302.1 - 0.025 15.1 9.4 2.5 8.9 0.6 4.6 2 2 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFH42302.1 - 0.056 13.2 1.5 1.9 8.4 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 KFH42302.1 - 0.087 12.7 6.1 0.6 10.0 0.2 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat FimP PF09766.4 KFH42303.1 - 1.3e-28 100.1 13.6 2e-28 99.4 9.4 1.2 1 0 0 1 1 1 1 Fms-interacting protein DUF4200 PF13863.1 KFH42303.1 - 0.057 13.3 17.0 0.11 12.4 3.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF948 PF06103.6 KFH42303.1 - 0.1 12.4 2.5 5.9 6.8 0.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Pinin_SDK_memA PF04696.8 KFH42303.1 - 0.8 9.3 13.0 1 8.9 2.9 2.3 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region Cortex-I_coil PF09304.5 KFH42303.1 - 1 9.4 12.6 0.46 10.5 2.0 2.3 2 0 0 2 2 2 0 Cortexillin I, coiled coil FUSC PF04632.7 KFH42303.1 - 3 6.1 10.2 3.5 5.9 7.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family K-box PF01486.12 KFH42303.1 - 4.7 7.0 13.1 0.33 10.7 1.5 3.1 2 2 0 2 2 2 0 K-box region DUF3450 PF11932.3 KFH42303.1 - 5.1 6.2 14.2 1.3 8.1 4.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) Aldedh PF00171.17 KFH42303.1 - 5.2 5.2 6.8 0.51 8.5 1.0 1.8 1 1 1 2 2 2 0 Aldehyde dehydrogenase family PRP1_N PF06424.7 KFH42303.1 - 8.2 6.7 8.3 19 5.6 5.6 1.7 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal Ras PF00071.17 KFH42305.1 - 2.3e-48 163.6 0.0 2.8e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFH42305.1 - 8.6e-15 55.2 0.0 1.5e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFH42305.1 - 2.5e-10 39.8 0.0 3.2e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 KFH42305.1 - 0.00051 20.1 0.1 0.0038 17.3 0.1 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 KFH42305.1 - 0.0051 15.9 0.0 0.0066 15.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.7 KFH42305.1 - 0.017 14.4 0.1 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.15 KFH42305.1 - 0.024 13.3 1.6 0.35 9.5 0.1 2.3 2 1 0 2 2 2 0 G-protein alpha subunit AAA_33 PF13671.1 KFH42305.1 - 0.067 13.0 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KFH42305.1 - 0.095 12.8 0.3 0.33 11.0 0.1 2.0 1 1 1 2 2 2 0 AAA domain UPF0079 PF02367.12 KFH42305.1 - 0.15 11.6 0.1 0.3 10.7 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Pkinase PF00069.20 KFH42306.1 - 0.0079 15.3 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Metal_resist PF13801.1 KFH42307.1 - 8.8 6.3 6.2 1.1 9.2 0.8 2.0 2 0 0 2 2 2 0 Heavy-metal resistance FKBP_C PF00254.23 KFH42308.1 - 1.5e-29 101.8 0.0 3.9e-29 100.5 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_6 PF13405.1 KFH42308.1 - 0.1 12.5 0.2 0.1 12.5 0.2 2.7 3 0 0 3 3 3 0 EF-hand domain PCNA_C PF02747.10 KFH42309.1 - 1.1e-51 174.0 0.1 2.9e-51 172.6 0.0 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.13 KFH42309.1 - 2e-46 156.5 5.4 2.5e-46 156.2 2.7 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.8 KFH42309.1 - 4.6e-09 35.7 0.1 5.4e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 KFH42309.1 - 0.0081 15.1 0.1 0.47 9.3 0.0 2.1 2 0 0 2 2 2 2 Hus1-like protein DNA_pol3_beta_3 PF02768.10 KFH42309.1 - 0.024 14.2 0.2 0.34 10.4 0.0 2.5 2 2 0 2 2 2 0 DNA polymerase III beta subunit, C-terminal domain PWI PF01480.12 KFH42310.1 - 2e-26 91.9 0.0 3.4e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 PWI domain RhoGAP PF00620.22 KFH42311.1 - 6.9e-41 139.3 0.2 1.2e-40 138.6 0.1 1.3 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 KFH42311.1 - 1.8e-09 37.7 0.0 3.4e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFH42311.1 - 1e-05 25.7 0.0 1.9e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Orbi_VP6 PF01516.11 KFH42311.1 - 0.0078 15.3 3.4 0.018 14.0 2.3 1.5 1 0 0 1 1 1 1 Orbivirus helicase VP6 PH_8 PF15409.1 KFH42311.1 - 0.033 14.2 0.1 0.19 11.8 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain PX PF00787.19 KFH42311.1 - 0.089 12.5 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 PX domain KH_1 PF00013.24 KFH42312.1 - 1.7e-39 133.2 6.6 1.5e-16 59.7 0.3 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KFH42312.1 - 4.5e-30 102.7 12.1 1.3e-11 43.8 1.8 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KFH42312.1 - 1.6e-12 46.8 4.6 0.0027 17.2 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KFH42312.1 - 4.9e-06 26.0 1.2 0.14 11.8 0.0 3.2 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 KFH42312.1 - 0.00021 21.0 4.1 0.79 9.5 0.1 3.5 3 0 0 3 3 3 2 NusA-like KH domain PfkB PF00294.19 KFH42313.1 - 1.4e-12 47.4 1.0 1.4e-08 34.2 0.1 2.6 2 1 0 2 2 2 2 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 KFH42313.1 - 2.7e-12 46.4 0.0 4.2e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DnaJ PF00226.26 KFH42314.1 - 2.4e-17 62.3 0.4 4.1e-17 61.6 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.8 KFH42314.1 - 0.042 13.8 2.5 0.067 13.2 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) LSM PF01423.17 KFH42315.1 - 2.8e-16 58.8 0.0 3.8e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain HlyIII PF03006.15 KFH42316.1 - 4.6e-54 183.1 18.6 5.6e-54 182.8 12.9 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF883 PF05957.8 KFH42316.1 - 0.017 15.5 6.4 0.16 12.4 0.8 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) tRNA_int_endo PF01974.12 KFH42317.1 - 5e-13 48.6 0.0 9.4e-13 47.7 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain RNase_PH PF01138.16 KFH42318.1 - 1.9e-26 92.9 0.0 3.4e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 NAD_binding_8 PF13450.1 KFH42319.1 - 1.2e-13 50.8 0.0 2.5e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFH42319.1 - 0.00025 20.0 0.0 0.00062 18.7 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFH42319.1 - 0.0018 18.1 0.0 0.011 15.5 0.0 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFH42319.1 - 0.0079 15.9 0.1 0.089 12.5 0.0 2.7 2 1 1 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KFH42319.1 - 0.017 13.9 0.0 0.027 13.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.19 KFH42319.1 - 0.043 12.8 0.3 0.28 10.1 0.1 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 KFH42319.1 - 0.15 12.4 0.0 0.46 10.9 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PAXNEB PF05625.6 KFH42320.1 - 2e-99 332.8 0.0 2.3e-99 332.6 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein RRM_1 PF00076.17 KFH42323.1 - 1e-23 82.7 1.0 7.9e-12 44.6 0.2 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH42323.1 - 5.9e-19 67.6 0.2 8.7e-12 44.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH42323.1 - 2.2e-16 59.5 0.2 2.1e-08 33.9 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.1 KFH42323.1 - 0.0064 16.0 0.2 0.019 14.4 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF4523) Guanylate_cyc PF00211.15 KFH42323.1 - 0.016 14.5 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain RRM_3 PF08777.6 KFH42323.1 - 0.033 14.0 0.6 0.093 12.5 0.4 1.8 1 1 0 1 1 1 0 RNA binding motif Calcipressin PF04847.7 KFH42323.1 - 0.06 12.9 0.1 0.11 12.0 0.1 1.5 1 1 0 1 1 1 0 Calcipressin Fungal_trans_2 PF11951.3 KFH42324.1 - 1.6e-10 40.1 5.0 7.3e-10 37.9 3.4 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH42324.1 - 0.00054 19.8 2.7 0.001 18.9 1.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_12 PF13424.1 KFH42325.1 - 1.1e-11 44.4 0.1 0.72 9.8 0.0 6.6 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFH42325.1 - 1e-09 38.1 5.6 2.8 8.8 0.0 9.2 9 1 0 9 9 9 2 Tetratricopeptide repeat Suf PF05843.9 KFH42325.1 - 9.8e-08 32.0 8.9 0.077 12.7 1.4 5.2 4 1 0 5 5 5 2 Suppressor of forked protein (Suf) TPR_15 PF13429.1 KFH42325.1 - 1.3e-06 27.7 5.7 8.3e-05 21.7 1.3 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 KFH42325.1 - 6.7e-06 25.9 4.8 1.2 8.9 0.1 6.3 6 2 1 7 7 7 2 Mad3/BUB1 homology region 1 TPR_11 PF13414.1 KFH42325.1 - 9e-06 25.2 2.0 11 5.7 0.0 6.2 7 0 0 7 7 7 0 TPR repeat TPR_16 PF13432.1 KFH42325.1 - 4.8e-05 23.9 1.1 0.87 10.3 0.0 6.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFH42325.1 - 0.00012 21.6 1.3 2.5 8.1 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFH42325.1 - 0.0002 21.6 0.0 2 8.7 0.0 4.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFH42325.1 - 0.002 17.9 12.1 1.2 9.2 0.0 6.1 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFH42325.1 - 0.045 13.9 2.8 31 5.0 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat RPN7 PF10602.4 KFH42325.1 - 0.052 12.9 0.3 0.18 11.1 0.1 2.1 2 1 0 2 2 2 0 26S proteasome subunit RPN7 TPR_7 PF13176.1 KFH42325.1 - 0.15 11.9 7.0 3 7.8 0.0 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat HAT PF02184.11 KFH42325.1 - 1.4 8.7 17.7 6.2 6.6 1.5 6.9 6 1 0 6 6 6 0 HAT (Half-A-TPR) repeat NPP1 PF05630.6 KFH42326.1 - 1.2e-61 208.0 0.4 1.5e-61 207.7 0.3 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Auxin_BP PF02041.11 KFH42326.1 - 0.098 12.0 0.0 0.2 11.0 0.0 1.5 2 0 0 2 2 2 0 Auxin binding protein Syja_N PF02383.13 KFH42327.1 - 4.9e-88 294.9 0.0 1e-87 293.9 0.0 1.5 2 0 0 2 2 2 1 SacI homology domain PolyA_pol PF01743.15 KFH42328.1 - 3.3e-25 88.7 0.1 6e-25 87.8 0.1 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain tRNA_NucTran2_2 PF13735.1 KFH42328.1 - 0.028 14.2 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative PolyA_pol_RNAbd PF12627.2 KFH42328.1 - 0.03 13.8 0.1 0.095 12.2 0.1 1.9 2 0 0 2 2 2 0 Probable RNA and SrmB- binding site of polymerase A MFS_1 PF07690.11 KFH42329.1 - 6.9e-29 100.6 45.1 1.2e-26 93.3 29.6 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily zf-C3HC4_3 PF13920.1 KFH42330.1 - 1.5e-07 30.9 12.9 2.7e-07 30.1 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FAM24 PF15193.1 KFH42330.1 - 1.5 9.0 8.3 3.8 7.7 5.8 1.7 1 0 0 1 1 1 0 FAM24 family Anp1 PF03452.9 KFH42331.1 - 8.7e-122 405.4 0.2 1.1e-120 401.8 0.0 2.4 3 0 0 3 3 3 1 Anp1 Rad54_N PF08658.5 KFH42331.1 - 0.069 12.9 1.1 0.12 12.1 0.8 1.3 1 0 0 1 1 1 0 Rad54 N terminal RNA_pol_Rpb8 PF03870.10 KFH42332.1 - 5e-38 130.3 0.1 5.6e-38 130.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 Peptidase_S7 PF00949.16 KFH42332.1 - 0.11 11.8 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease NUDIX PF00293.23 KFH42333.1 - 4.9e-11 42.4 0.1 7.7e-11 41.7 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain FlgM PF04316.8 KFH42333.1 - 0.032 14.1 0.0 0.35 10.8 0.0 2.1 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM ThiF PF00899.16 KFH42334.1 - 3.3e-12 46.4 0.0 1.4e-11 44.3 0.0 2.0 2 0 0 2 2 2 1 ThiF family Ldh_1_N PF00056.18 KFH42335.1 - 2.9e-28 98.4 0.1 4.2e-28 97.9 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KFH42335.1 - 3.4e-24 85.5 0.0 4.6e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain ThiF PF00899.16 KFH42335.1 - 0.0044 16.8 2.6 0.0084 15.9 1.4 1.8 2 1 0 2 2 2 1 ThiF family ApbA PF02558.11 KFH42335.1 - 0.013 14.9 0.2 0.059 12.8 0.2 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 KFH42335.1 - 0.015 15.7 1.6 0.087 13.2 0.5 2.4 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.9 KFH42335.1 - 0.033 13.5 3.3 0.34 10.2 2.3 2.2 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Malic_M PF03949.10 KFH42335.1 - 0.033 13.7 0.0 0.081 12.4 0.0 1.6 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain TrkA_N PF02254.13 KFH42335.1 - 0.13 12.2 0.7 0.37 10.8 0.5 1.8 1 1 0 1 1 1 0 TrkA-N domain Fungal_trans PF04082.13 KFH42336.1 - 1.7e-27 95.9 0.0 2.7e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH42336.1 - 9.5e-08 31.8 12.9 1.8e-07 30.9 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BatA PF07584.6 KFH42336.1 - 0.054 13.7 1.7 53 4.1 0.0 4.1 4 1 0 4 4 4 0 Aerotolerance regulator N-terminal AMP-binding PF00501.23 KFH42337.1 - 1.9e-61 207.7 0.0 3e-61 207.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 KFH42337.1 - 2.4e-11 43.7 0.0 5.9e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.19 KFH42337.1 - 1.7e-09 36.7 3.0 0.086 12.3 0.0 5.8 6 0 0 6 6 6 3 Bacterial transferase hexapeptide (six repeats) AMP-binding_C PF13193.1 KFH42337.1 - 2.1e-06 28.5 0.7 0.032 15.1 0.1 2.6 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain GH3 PF03321.8 KFH42337.1 - 0.45 8.9 0.0 5.9 5.2 0.0 2.0 2 0 0 2 2 2 0 GH3 auxin-responsive promoter ATP-synt_D PF01813.12 KFH42338.1 - 6.2e-56 189.0 5.9 4.8e-51 173.1 0.9 2.2 2 0 0 2 2 2 2 ATP synthase subunit D TT_ORF2 PF02957.10 KFH42338.1 - 0.3 11.8 3.0 0.53 10.9 2.1 1.4 1 0 0 1 1 1 0 TT viral ORF2 zf-RING_5 PF14634.1 KFH42339.1 - 4.4e-07 29.5 7.8 8.9e-07 28.5 5.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFH42339.1 - 0.00018 21.4 3.4 0.00051 20.0 2.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFH42339.1 - 0.0005 19.8 7.6 0.0005 19.8 5.3 1.7 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFH42339.1 - 0.0011 18.6 7.1 0.0019 17.7 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFH42339.1 - 0.0062 16.1 7.0 0.013 15.1 4.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFH42339.1 - 0.012 15.4 2.3 0.029 14.2 1.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Myosin_tail_1 PF01576.14 KFH42339.1 - 0.012 13.3 2.2 0.016 12.9 1.6 1.0 1 0 0 1 1 1 0 Myosin tail EMP24_GP25L PF01105.19 KFH42339.1 - 0.023 14.4 1.9 0.037 13.7 1.3 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD zf-RING_4 PF14570.1 KFH42339.1 - 0.037 13.6 2.6 0.087 12.4 1.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.6 KFH42339.1 - 0.077 12.8 3.4 3.5 7.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Cupin_8 PF13621.1 KFH42339.1 - 0.091 12.2 0.4 0.12 11.8 0.3 1.2 1 0 0 1 1 1 0 Cupin-like domain MscS_porin PF12795.2 KFH42339.1 - 0.13 11.5 3.6 0.2 10.9 2.5 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Fzo_mitofusin PF04799.8 KFH42339.1 - 0.16 11.3 2.6 0.075 12.4 0.3 1.5 2 0 0 2 2 1 0 fzo-like conserved region Tup_N PF08581.5 KFH42339.1 - 0.16 12.1 3.6 0.39 10.9 2.5 1.6 1 0 0 1 1 1 0 Tup N-terminal DUF342 PF03961.8 KFH42339.1 - 0.26 9.6 1.8 0.34 9.2 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1043 PF06295.7 KFH42339.1 - 0.31 10.6 4.6 0.52 9.9 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) zf-CHY PF05495.7 KFH42339.1 - 0.38 10.9 5.8 0.8 9.9 4.0 1.5 1 0 0 1 1 1 0 CHY zinc finger C1_4 PF07975.7 KFH42339.1 - 0.58 10.2 4.1 6 6.9 1.7 2.6 2 0 0 2 2 2 0 TFIIH C1-like domain IncA PF04156.9 KFH42339.1 - 0.92 9.0 2.7 1.3 8.5 1.9 1.2 1 0 0 1 1 1 0 IncA protein zf-rbx1 PF12678.2 KFH42339.1 - 0.96 9.6 5.3 2.5 8.2 3.4 1.9 2 0 0 2 2 2 0 RING-H2 zinc finger zf-MIZ PF02891.15 KFH42339.1 - 1.1 8.8 5.8 2.4 7.7 4.0 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Glyco_transf_15 PF01793.11 KFH42340.1 - 5.3e-121 403.6 0.7 6.5e-121 403.3 0.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Peptidase_S10 PF00450.17 KFH42341.1 - 8.3e-57 193.2 0.0 1.1e-56 192.7 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DUF775 PF05603.7 KFH42343.1 - 2.8e-51 173.9 0.0 3.9e-51 173.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF775) DUF2370 PF10176.4 KFH42343.1 - 0.084 12.1 0.1 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Sec7 PF01369.15 KFH42344.1 - 2.1e-57 193.8 0.0 9.4e-57 191.7 0.0 2.1 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.2 KFH42344.1 - 1.4e-16 60.3 0.0 5.3e-10 38.9 0.1 2.7 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF913 PF06025.7 KFH42344.1 - 0.26 9.9 4.9 0.43 9.2 2.2 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) NQR2_RnfD_RnfE PF03116.10 KFH42344.1 - 0.35 10.0 0.5 0.92 8.6 0.2 1.8 2 0 0 2 2 2 0 NQR2, RnfD, RnfE family FancD2 PF14631.1 KFH42345.1 - 0.23 8.5 0.0 0.29 8.1 0.0 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease DUF2454 PF10521.4 KFH42346.1 - 1.1e-60 205.0 0.0 1.4e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) HEAT PF02985.17 KFH42346.1 - 0.012 15.5 0.9 0.18 11.9 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat GFA PF04828.9 KFH42347.1 - 3.3e-07 30.1 2.0 0.014 15.2 0.1 2.5 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme RNA_pol_Rpb4 PF03874.11 KFH42348.1 - 1.5e-16 60.4 0.0 1.9e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 HRDC PF00570.18 KFH42348.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 HRDC domain RtcR PF06956.6 KFH42349.1 - 0.047 13.0 0.0 0.062 12.6 0.0 1.1 1 0 0 1 1 1 0 Regulator of RNA terminal phosphate cyclase PseudoU_synth_1 PF01416.15 KFH42350.1 - 2.5e-26 92.1 0.0 8.9e-20 71.0 0.0 3.1 2 1 0 2 2 2 2 tRNA pseudouridine synthase 2OG-Fe_Oxy_2 PF10014.4 KFH42350.1 - 0.06 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe dioxygenase AAA PF00004.24 KFH42351.1 - 6e-52 175.3 0.0 2.1e-39 134.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFH42351.1 - 7.4e-12 45.5 0.0 0.00042 20.4 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KFH42351.1 - 2e-09 37.6 0.0 0.0015 18.5 0.0 3.1 2 1 0 3 3 3 2 AAA ATPase domain AAA_14 PF13173.1 KFH42351.1 - 9.7e-08 31.9 0.0 0.005 16.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 KFH42351.1 - 1.1e-07 31.1 0.2 0.0037 16.3 0.0 2.7 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 KFH42351.1 - 1.1e-07 30.9 0.0 0.0095 14.6 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_2 PF07724.9 KFH42351.1 - 5.3e-07 29.6 0.0 0.00015 21.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KFH42351.1 - 6e-07 29.2 0.0 0.0014 18.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KFH42351.1 - 2.3e-06 27.2 0.2 0.021 14.5 0.1 3.1 3 0 0 3 3 3 2 Part of AAA domain AAA_33 PF13671.1 KFH42351.1 - 4.2e-06 26.6 0.0 0.13 12.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KFH42351.1 - 5.6e-06 27.1 0.0 0.01 16.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain CDC48_2 PF02933.12 KFH42351.1 - 1.3e-05 24.7 0.1 0.0016 18.0 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 Mg_chelatase PF01078.16 KFH42351.1 - 1.4e-05 24.3 0.2 0.0043 16.2 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KFH42351.1 - 1.7e-05 24.8 0.0 0.11 12.6 0.0 2.9 2 0 0 2 2 2 2 RNA helicase CDC48_N PF02359.13 KFH42351.1 - 2.5e-05 24.1 0.0 0.00022 21.0 0.0 2.3 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain Arch_ATPase PF01637.13 KFH42351.1 - 7.1e-05 22.6 0.1 10 5.7 0.0 4.1 2 2 2 4 4 4 0 Archaeal ATPase AAA_18 PF13238.1 KFH42351.1 - 9.9e-05 22.6 0.0 0.036 14.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain NACHT PF05729.7 KFH42351.1 - 0.00014 21.5 0.5 0.55 9.8 0.0 3.7 4 0 0 4 4 3 1 NACHT domain IstB_IS21 PF01695.12 KFH42351.1 - 0.00015 21.2 0.1 0.13 11.6 0.0 2.9 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_25 PF13481.1 KFH42351.1 - 0.00021 20.7 0.9 0.47 9.8 0.0 3.2 2 1 0 3 3 3 1 AAA domain Sigma54_activat PF00158.21 KFH42351.1 - 0.00029 20.3 0.0 0.64 9.4 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.1 KFH42351.1 - 0.0004 20.0 0.3 0.052 13.1 0.1 2.5 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 KFH42351.1 - 0.00059 19.0 0.2 0.015 14.3 0.1 2.4 2 0 0 2 2 2 1 KaiC PhoH PF02562.11 KFH42351.1 - 0.0012 18.1 0.0 1.3 8.2 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein ABC_tran PF00005.22 KFH42351.1 - 0.0022 18.2 1.0 0.21 11.9 0.0 3.0 3 0 0 3 3 3 1 ABC transporter Parvo_NS1 PF01057.12 KFH42351.1 - 0.0043 15.9 0.2 1 8.1 0.0 2.7 3 0 0 3 3 3 1 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 KFH42351.1 - 0.017 14.0 0.2 1.6 7.5 0.2 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.1 KFH42351.1 - 0.017 15.0 0.0 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KFH42351.1 - 0.026 13.6 0.1 2.4 7.2 0.0 2.6 3 0 0 3 3 2 0 Zeta toxin ResIII PF04851.10 KFH42351.1 - 0.051 13.4 0.3 5.5 6.7 0.0 2.6 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_29 PF13555.1 KFH42351.1 - 0.06 12.8 0.1 4.5 6.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain DEAD PF00270.24 KFH42351.1 - 0.078 12.4 0.2 9.7 5.6 0.0 3.2 2 1 0 3 3 3 0 DEAD/DEAH box helicase AAA_11 PF13086.1 KFH42351.1 - 0.082 12.4 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 KFH42351.1 - 0.11 12.5 0.0 25 4.9 0.0 2.9 2 0 0 2 2 2 0 Sigma-54 interaction domain DAP3 PF10236.4 KFH42351.1 - 0.12 11.3 0.1 2.9 6.7 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF2075 PF09848.4 KFH42351.1 - 0.13 11.2 0.0 0.94 8.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ATG16 PF08614.6 KFH42352.1 - 0.00049 19.9 3.9 0.00049 19.9 2.7 1.8 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) DUF4600 PF15372.1 KFH42352.1 - 0.0064 16.7 0.9 0.0091 16.2 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4600) DegS PF05384.6 KFH42352.1 - 0.0082 15.3 2.9 0.011 14.9 2.0 1.1 1 0 0 1 1 1 1 Sensor protein DegS DUF972 PF06156.8 KFH42352.1 - 0.0087 16.3 1.3 0.013 15.8 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF972) SlyX PF04102.7 KFH42352.1 - 0.012 15.9 1.1 0.012 15.9 0.8 2.0 3 0 0 3 3 2 0 SlyX Seryl_tRNA_N PF02403.17 KFH42352.1 - 0.013 15.5 2.8 0.018 15.0 2.0 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain CENP-Q PF13094.1 KFH42352.1 - 0.015 15.3 2.9 0.019 15.0 2.0 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit COG5 PF10392.4 KFH42352.1 - 0.018 15.0 0.7 0.025 14.5 0.5 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Spc7 PF08317.6 KFH42352.1 - 0.019 13.6 3.1 0.024 13.3 2.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Cep57_MT_bd PF06657.8 KFH42352.1 - 0.037 13.9 0.2 0.064 13.2 0.2 1.4 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 PEARLI-4 PF05278.7 KFH42352.1 - 0.04 13.2 0.9 0.055 12.8 0.6 1.2 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Cluap1 PF10234.4 KFH42352.1 - 0.047 12.9 2.5 0.054 12.7 1.7 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 Striatin PF08232.7 KFH42352.1 - 0.054 13.8 5.2 0.076 13.3 3.6 1.2 1 0 0 1 1 1 0 Striatin family Alpha-2-MRAP_C PF06401.6 KFH42352.1 - 0.066 13.0 0.2 0.066 13.0 0.2 1.4 2 0 0 2 2 1 0 Alpha-2-macroglobulin RAP, C-terminal domain DUF1664 PF07889.7 KFH42352.1 - 0.069 12.9 1.2 0.13 12.0 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) SPX PF03105.14 KFH42352.1 - 0.11 12.2 3.1 0.12 12.1 2.1 1.0 1 0 0 1 1 1 0 SPX domain Allexi_40kDa PF05549.6 KFH42352.1 - 0.12 11.6 1.0 0.15 11.3 0.7 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Fib_alpha PF08702.5 KFH42352.1 - 0.14 12.3 1.8 0.28 11.3 1.3 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF724 PF05266.9 KFH42352.1 - 0.15 11.6 2.9 0.18 11.3 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Prefoldin PF02996.12 KFH42352.1 - 0.22 11.2 3.2 0.34 10.5 2.2 1.3 1 0 0 1 1 1 0 Prefoldin subunit IncA PF04156.9 KFH42352.1 - 0.34 10.4 5.7 0.58 9.7 3.9 1.4 1 1 0 1 1 1 0 IncA protein OmpH PF03938.9 KFH42352.1 - 0.59 10.0 6.8 0.78 9.6 4.7 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Spc24 PF08286.6 KFH42352.1 - 0.96 9.1 7.2 1.6 8.4 5.0 1.5 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 zf-C4H2 PF10146.4 KFH42352.1 - 1.5 8.7 5.8 2.4 8.1 4.0 1.3 1 1 0 1 1 1 0 Zinc finger-containing protein DGF-1_C PF11040.3 KFH42352.1 - 1.6 8.7 5.0 9.4 6.1 0.0 2.6 2 1 0 3 3 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus TMF_DNA_bd PF12329.3 KFH42352.1 - 2.9 7.7 8.5 0.5 10.2 3.4 1.6 2 0 0 2 2 1 0 TATA element modulatory factor 1 DNA binding APC_CDC26 PF10471.4 KFH42352.1 - 3.9 8.2 11.4 10 6.9 6.9 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex APC subunit 1 Ribosomal_S2 PF00318.15 KFH42353.1 - 2.3e-42 144.6 0.0 2.5e-22 79.1 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 COX14 PF14880.1 KFH42354.1 - 0.0017 17.9 0.2 0.0028 17.2 0.1 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c assembly DUF1467 PF07330.7 KFH42354.1 - 0.016 14.9 0.5 0.025 14.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1467) vATP-synt_AC39 PF01992.11 KFH42355.1 - 3.4e-117 391.3 0.0 3.9e-117 391.1 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Ion_trans PF00520.26 KFH42356.1 - 1.4e-08 34.2 18.5 2.7e-08 33.3 11.5 2.4 2 1 0 2 2 2 1 Ion transport protein PKD_channel PF08016.7 KFH42356.1 - 5.4e-05 21.7 12.1 0.0096 14.3 8.4 2.2 1 1 0 1 1 1 1 Polycystin cation channel Band_7 PF01145.20 KFH42357.1 - 9.8e-27 94.0 3.1 9.8e-27 94.0 2.2 1.7 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 KFH42357.1 - 0.077 12.4 0.8 0.1 12.0 0.1 1.6 2 0 0 2 2 2 0 SPFH domain-Band 7 family Zn_clus PF00172.13 KFH42358.1 - 1.6e-07 31.0 8.6 3.6e-07 29.9 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFH42358.1 - 0.0072 14.9 0.2 0.011 14.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DEAD PF00270.24 KFH42360.1 - 4.7e-35 120.5 0.0 1.4e-34 119.0 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFH42360.1 - 1.1e-18 66.8 0.0 2.5e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KFH42360.1 - 2.9e-18 65.1 0.0 5.8e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 KFH42360.1 - 0.0061 16.4 0.9 0.0084 15.9 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TMEM247 PF15444.1 KFH42362.1 - 0.01 15.6 0.3 0.012 15.4 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 ATG16 PF08614.6 KFH42362.1 - 0.048 13.4 3.0 0.057 13.2 2.0 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Stm1_N PF09598.5 KFH42362.1 - 0.69 10.6 10.3 0.5 11.0 3.4 2.3 1 1 1 2 2 2 0 Stm1 DUF4603 PF15376.1 KFH42362.1 - 0.76 6.8 9.9 1 6.4 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) CAF-1_p150 PF11600.3 KFH42362.1 - 3.5 6.9 12.9 0.073 12.4 4.4 1.5 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Pribosyl_synth PF14572.1 KFH42363.1 - 1.6e-42 145.3 1.1 5e-38 130.7 0.2 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 KFH42363.1 - 6.2e-32 109.7 0.0 3.4e-31 107.3 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 KFH42363.1 - 1.1e-11 44.5 0.2 3e-11 43.1 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain HSP70 PF00012.15 KFH42364.1 - 7.3e-61 205.8 4.5 4.2e-58 196.7 0.1 3.5 3 1 0 3 3 3 2 Hsp70 protein FGGY_C PF02782.11 KFH42364.1 - 0.054 13.1 0.9 0.18 11.3 0.3 2.2 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 KFH42364.1 - 0.14 12.0 2.2 21 5.0 0.1 3.9 3 1 0 3 3 3 0 Cell division protein FtsA Cir_N PF10197.4 KFH42365.1 - 0.00011 22.1 0.9 0.00011 22.1 0.6 4.3 3 1 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR API5 PF05918.6 KFH42366.1 - 0.43 9.0 6.4 1 7.7 4.4 1.6 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) RasGEF PF00617.14 KFH42367.1 - 1.1e-50 172.0 0.1 2.3e-50 170.9 0.1 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KFH42367.1 - 4.2e-14 52.5 0.2 1.3e-13 50.9 0.1 1.9 1 1 1 2 2 2 1 RasGEF N-terminal motif Ras PF00071.17 KFH42368.1 - 7.2e-22 77.5 0.0 9.6e-22 77.0 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFH42368.1 - 2.4e-11 44.1 0.0 3.1e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFH42368.1 - 2.7e-07 30.0 0.0 5e-07 29.1 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KFH42368.1 - 0.0091 14.7 0.1 0.071 11.7 0.0 2.0 2 1 0 2 2 2 1 G-protein alpha subunit PduV-EutP PF10662.4 KFH42368.1 - 0.025 14.0 0.1 0.073 12.5 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 KFH42368.1 - 0.036 13.2 0.0 0.069 12.3 0.0 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Ribosomal_S15 PF00312.17 KFH42370.1 - 6.6e-15 54.6 0.4 6.6e-15 54.6 0.3 2.2 2 1 1 3 3 3 1 Ribosomal protein S15 U1snRNP70_N PF12220.3 KFH42370.1 - 0.032 14.5 1.1 0.032 14.5 0.8 2.9 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal PIG-H PF10181.4 KFH42371.1 - 4.5e-23 80.6 0.0 6.5e-23 80.1 0.0 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component CRM1_C PF08767.6 KFH42372.1 - 2.6e-131 437.2 2.0 2.6e-131 437.2 1.4 3.1 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 KFH42372.1 - 8.6e-42 142.5 10.7 2.9e-41 140.8 5.1 3.6 3 1 1 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 KFH42372.1 - 3e-11 43.0 0.0 1.2e-10 41.1 0.0 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.3 KFH42372.1 - 0.0028 17.5 1.7 0.17 11.8 0.0 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) HD_assoc PF13286.1 KFH42372.1 - 0.047 13.9 0.8 62 3.9 0.2 4.4 5 0 0 5 5 5 0 Phosphohydrolase-associated domain C8 PF08742.6 KFH42372.1 - 0.096 12.9 2.2 1.1 9.6 0.0 3.1 3 0 0 3 3 3 0 C8 domain Vac14_Fab1_bd PF12755.2 KFH42372.1 - 0.6 10.5 4.4 5.9 7.3 0.0 4.7 7 0 0 7 7 7 0 Vacuolar 14 Fab1-binding region Nop PF01798.13 KFH42373.1 - 8e-54 181.0 0.7 2e-53 179.7 0.3 1.9 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 KFH42373.1 - 5.7e-23 80.4 0.0 1e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KFH42373.1 - 1.9e-21 76.0 2.0 1.9e-21 76.0 1.4 2.7 2 0 0 2 2 2 1 NOP5NT (NUC127) domain Fringe PF02434.11 KFH42374.1 - 2.3e-06 27.0 0.7 4.3e-05 22.8 0.5 2.2 1 1 0 1 1 1 1 Fringe-like Inhibitor_I68 PF10468.4 KFH42374.1 - 0.22 11.7 4.9 0.15 12.2 1.0 2.3 2 0 0 2 2 2 0 Carboxypeptidase inhibitor I68 NAD_binding_1 PF00175.16 KFH42375.1 - 3.1e-20 72.7 0.0 5.7e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KFH42375.1 - 2.6e-17 62.7 0.0 5.3e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KFH42375.1 - 3.1e-05 23.9 0.0 0.0036 17.2 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KFH42375.1 - 0.00051 20.0 0.1 0.0027 17.6 0.0 2.1 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain APC10 PF03256.11 KFH42376.1 - 4.1e-46 157.0 0.0 6.1e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Nop14 PF04147.7 KFH42376.1 - 5.2 4.8 13.5 6.8 4.4 9.4 1.1 1 0 0 1 1 1 0 Nop14-like family ATP-grasp_2 PF08442.5 KFH42377.1 - 5e-77 257.8 1.1 6.3e-77 257.5 0.2 1.6 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 KFH42377.1 - 6.5e-28 97.2 0.4 1.3e-27 96.2 0.3 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 KFH42377.1 - 1e-08 34.6 0.0 2.3e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 KFH42377.1 - 4.4e-05 23.1 0.7 0.00086 18.9 0.1 2.5 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 KFH42377.1 - 0.0038 16.9 0.0 0.0066 16.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KFH42377.1 - 0.0081 15.6 0.0 0.18 11.2 0.0 2.6 1 1 1 2 2 2 1 RimK-like ATP-grasp domain OKR_DC_1_N PF03709.10 KFH42377.1 - 0.042 13.9 0.1 0.64 10.0 0.0 2.6 2 1 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain KxDL PF10241.4 KFH42378.1 - 5.3e-31 106.3 2.1 7.2e-31 105.9 1.4 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein Mating_C PF12737.2 KFH42378.1 - 0.00082 18.3 7.5 0.013 14.4 0.6 2.2 2 0 0 2 2 2 2 C-terminal domain of homeodomain 1 XylR_N PF06505.6 KFH42378.1 - 0.016 14.6 0.1 0.022 14.1 0.1 1.2 1 0 0 1 1 1 0 Activator of aromatic catabolism Syntaxin PF00804.20 KFH42378.1 - 0.041 14.0 0.9 0.31 11.2 0.0 2.2 1 1 1 2 2 2 0 Syntaxin DUF883 PF05957.8 KFH42378.1 - 1.6 9.1 6.0 3.4 8.1 2.0 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) CTP_transf_1 PF01148.15 KFH42379.1 - 1.4e-16 60.9 9.5 2.4e-14 53.6 2.9 2.1 1 1 1 2 2 2 2 Cytidylyltransferase family RPAP2_Rtr1 PF04181.8 KFH42381.1 - 2.5e-19 69.1 0.0 4e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Rtr1/RPAP2 family TrkA_C PF02080.16 KFH42381.1 - 0.054 13.0 0.0 0.53 9.9 0.0 2.3 1 1 1 2 2 2 0 TrkA-C domain JAB PF01398.16 KFH42382.1 - 3e-08 33.3 0.4 3.2e-07 30.0 0.3 2.2 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease TGT PF01702.13 KFH42384.1 - 4.2e-86 288.0 0.0 5.3e-86 287.7 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Transferase PF02458.10 KFH42385.1 - 0.0002 19.9 0.0 0.00058 18.4 0.0 1.8 1 1 0 1 1 1 1 Transferase family Spc97_Spc98 PF04130.8 KFH42386.1 - 1.9e-66 224.5 0.0 1.3e-65 221.7 0.0 2.1 2 1 0 2 2 2 1 Spc97 / Spc98 family DUF1158 PF06643.6 KFH42386.1 - 0.044 14.1 0.5 0.18 12.1 0.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1158) TRI12 PF06609.8 KFH42387.1 - 4.2e-45 154.0 19.6 5e-45 153.8 13.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KFH42387.1 - 5.9e-16 58.1 50.5 3.7e-15 55.5 32.2 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH42387.1 - 4.7e-07 28.7 8.5 4.7e-07 28.7 5.9 3.8 4 0 0 4 4 4 2 Sugar (and other) transporter EpuA PF11772.3 KFH42387.1 - 0.0015 17.9 0.6 0.0096 15.3 0.4 2.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase subunit beta MFS_1 PF07690.11 KFH42388.1 - 2.6e-31 108.6 33.1 2.6e-31 108.6 23.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH42388.1 - 5.2e-12 45.0 18.4 1.2e-11 43.8 12.7 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter ATG22 PF11700.3 KFH42388.1 - 2.8e-05 22.7 6.1 2.8e-05 22.7 4.2 2.1 2 1 1 3 3 3 1 Vacuole effluxer Atg22 like TRI12 PF06609.8 KFH42388.1 - 0.0015 16.8 0.4 0.0024 16.1 0.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FGE-sulfatase PF03781.11 KFH42389.1 - 7.9e-19 68.0 0.4 2.7e-17 62.9 0.3 2.6 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Methyltransf_33 PF10017.4 KFH42389.1 - 1e-16 60.9 0.0 1.9e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent DinB_2 PF12867.2 KFH42389.1 - 7.9e-10 39.1 4.6 1.4e-09 38.3 0.8 3.0 4 0 0 4 4 4 1 DinB superfamily DUF3431 PF11913.3 KFH42391.1 - 1.2e-82 276.6 0.0 1.5e-82 276.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) adh_short PF00106.20 KFH42392.1 - 2.3e-32 112.2 1.8 2.9e-32 111.9 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH42392.1 - 3.4e-27 95.7 0.0 4.1e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH42392.1 - 1.1e-16 60.9 0.5 1.6e-16 60.5 0.4 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KFH42392.1 - 0.0048 16.5 2.1 0.0075 15.9 1.4 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 KFH42392.1 - 0.02 13.9 0.2 0.033 13.2 0.2 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DFP PF04127.10 KFH42392.1 - 0.093 12.3 0.9 0.15 11.6 0.6 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Ribosomal_S21 PF01165.15 KFH42393.1 - 5.6e-12 44.9 6.5 9.2e-12 44.2 4.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 PAT1 PF09770.4 KFH42393.1 - 1.8 6.6 7.3 1.7 6.7 5.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 KFH42393.1 - 3.3 7.0 19.1 3.8 6.8 13.2 1.1 1 0 0 1 1 1 0 Vta1 like DUF1681 PF07933.9 KFH42394.1 - 9.7e-56 187.7 0.0 1.3e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) 2-Hacid_dh_C PF02826.14 KFH42395.1 - 2.2e-53 180.0 0.0 2.9e-53 179.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFH42395.1 - 3.1e-17 62.2 0.0 4.1e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KFH42395.1 - 0.00014 21.7 0.1 0.00023 21.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 KFH42395.1 - 0.0052 16.1 0.0 0.0084 15.4 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain DUF2324 PF10086.4 KFH42396.1 - 0.0035 16.5 1.3 0.0035 16.5 0.9 1.6 2 0 0 2 2 2 1 Putative membrane peptidase family (DUF2324) O-antigen_lig PF13425.1 KFH42396.1 - 0.12 12.3 6.9 0.45 10.4 0.5 2.7 3 0 0 3 3 3 0 O-antigen ligase like membrane protein DUF3375 PF11855.3 KFH42398.1 - 0.087 11.5 0.1 0.087 11.5 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3375) Zn_clus PF00172.13 KFH42399.1 - 0.015 15.2 15.7 0.024 14.5 10.9 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M43 PF05572.8 KFH42400.1 - 7.8e-18 64.5 0.0 1.4e-17 63.7 0.0 1.4 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 KFH42400.1 - 1.6e-05 24.9 0.1 2.6e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KFH42400.1 - 4.5e-05 23.5 0.1 6.5e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KFH42400.1 - 0.00024 21.6 0.2 0.00052 20.5 0.0 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KFH42400.1 - 0.0012 18.6 0.0 0.0015 18.2 0.0 1.4 1 1 0 1 1 1 1 Matrixin Reprolysin_4 PF13583.1 KFH42400.1 - 0.0029 17.1 0.5 0.0044 16.5 0.3 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.11 KFH42400.1 - 0.044 13.4 0.4 0.093 12.4 0.2 1.6 1 1 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M66 PF10462.4 KFH42400.1 - 0.056 12.3 0.4 0.086 11.7 0.2 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M54 PF07998.6 KFH42400.1 - 0.13 11.9 0.1 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 Mit_ribos_Mrp51 PF11709.3 KFH42401.1 - 1.3e-66 225.0 0.0 1.5e-66 224.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit AdoHcyase PF05221.12 KFH42402.1 - 2.1e-136 453.1 0.1 2.5e-136 452.8 0.1 1.1 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 KFH42402.1 - 6.1e-84 279.7 1.7 9.6e-84 279.1 1.2 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 KFH42402.1 - 4.6e-07 29.1 0.1 9.8e-07 28.0 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 KFH42402.1 - 0.0034 16.7 0.4 0.0062 15.9 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain ELFV_dehydrog PF00208.16 KFH42402.1 - 0.0073 15.9 0.1 0.014 15.0 0.1 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.13 KFH42402.1 - 0.04 13.9 0.0 0.085 12.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 KFH42402.1 - 0.043 13.4 0.5 0.082 12.5 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.20 KFH42402.1 - 0.06 13.2 0.8 6.4 6.6 0.1 2.6 2 0 0 2 2 2 0 short chain dehydrogenase SH3_1 PF00018.23 KFH42403.1 - 4.8e-10 38.6 0.2 4.8e-10 38.6 0.1 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KFH42403.1 - 2.1e-09 36.8 0.2 4.4e-09 35.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFH42403.1 - 1.1e-08 34.3 0.0 2.6e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Mu-transpos_C PF09299.6 KFH42403.1 - 0.39 10.6 0.3 0.76 9.6 0.2 1.3 1 0 0 1 1 1 0 Mu transposase, C-terminal Fungal_trans PF04082.13 KFH42404.1 - 3.8e-23 81.6 0.1 7e-23 80.8 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH42404.1 - 7.9e-06 25.6 6.5 1.6e-05 24.6 4.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mto2_bdg PF12808.2 KFH42404.1 - 0.06 13.4 1.8 0.19 11.8 1.3 1.8 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Arabinose_Iso_C PF11762.3 KFH42404.1 - 0.069 12.7 0.0 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 L-arabinose isomerase C-terminal domain UPF0147 PF03685.8 KFH42404.1 - 0.17 11.7 2.3 0.24 11.3 0.0 2.3 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0147) Zn_clus PF00172.13 KFH42406.1 - 1.4e-09 37.6 8.9 2.4e-09 36.9 6.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.8 KFH42407.1 - 2.8e-61 206.7 0.0 3.7e-61 206.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KFH42407.1 - 5.9e-10 38.4 0.1 1.3e-09 37.3 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 KFH42407.1 - 4e-05 23.5 0.1 7.8e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH42407.1 - 0.0007 19.3 0.0 0.00095 18.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFH42407.1 - 0.0025 17.0 0.0 0.64 9.2 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Med22 PF06179.7 KFH42408.1 - 0.00018 21.4 0.0 0.00024 21.0 0.0 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Abhydrolase_6 PF12697.2 KFH42409.1 - 8e-12 45.5 0.1 1.6e-11 44.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH42409.1 - 2e-09 37.3 0.0 3.7e-09 36.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KFH42409.1 - 0.072 12.9 0.1 0.18 11.6 0.1 1.7 1 1 0 1 1 1 0 Putative lysophospholipase DUF2305 PF10230.4 KFH42409.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Senescence PF06911.7 KFH42410.1 - 1.6e-45 154.9 4.3 3.1e-45 154.0 3.0 1.5 1 0 0 1 1 1 1 Senescence-associated protein adh_short PF00106.20 KFH42411.1 - 7.5e-18 65.0 1.7 1.4e-17 64.1 1.2 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH42411.1 - 3.4e-08 33.5 0.3 1.3e-07 31.6 0.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH42411.1 - 1.8e-06 27.7 0.4 4e-06 26.6 0.3 1.5 1 0 0 1 1 1 1 KR domain Methyltransf_25 PF13649.1 KFH42411.1 - 0.00029 21.1 0.0 0.001 19.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Epimerase PF01370.16 KFH42411.1 - 0.0024 17.3 0.1 0.0057 16.1 0.1 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.1 KFH42411.1 - 0.0036 17.3 0.4 0.0056 16.7 0.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFH42411.1 - 0.032 14.2 0.2 0.072 13.1 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 KFH42411.1 - 0.034 13.7 0.4 0.053 13.1 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.19 KFH42411.1 - 0.046 12.6 0.2 0.071 12.0 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFH42411.1 - 0.066 12.0 0.9 0.11 11.3 0.7 1.3 1 0 0 1 1 1 0 FAD binding domain UPF0146 PF03686.8 KFH42411.1 - 0.13 12.1 0.0 0.48 10.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) Bestrophin PF01062.16 KFH42412.1 - 3.6e-46 157.4 0.7 4e-28 98.2 0.1 2.0 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DUF651 PF04895.7 KFH42412.1 - 0.0092 15.5 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 1 Archaeal protein of unknown function (DUF651) VIT1 PF01988.14 KFH42412.1 - 0.011 15.2 1.5 0.014 14.9 0.0 1.9 2 1 0 2 2 2 0 VIT family IF-2B PF01008.12 KFH42413.1 - 8.7e-33 113.5 0.0 1.1e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Pyr_redox_3 PF13738.1 KFH42414.1 - 1.1e-20 74.5 0.0 4.8e-19 69.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFH42414.1 - 5.2e-17 61.2 0.9 4.6e-15 54.8 0.3 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KFH42414.1 - 5.7e-09 35.8 0.0 5.7e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KFH42414.1 - 2.3e-08 33.3 0.0 1.6e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KFH42414.1 - 8.8e-07 28.9 0.0 2.4e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFH42414.1 - 7.2e-05 22.6 0.0 0.0078 15.9 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Endonuc-dimeris PF09124.5 KFH42414.1 - 0.041 13.4 1.7 0.043 13.4 0.3 1.7 2 0 0 2 2 2 0 T4 recombination endonuclease VII, dimerisation Pyr_redox_3 PF13738.1 KFH42415.1 - 1.5e-17 64.3 0.0 2.7e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFH42415.1 - 9e-17 60.4 0.0 8.7e-16 57.2 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KFH42415.1 - 4.2e-11 42.6 0.0 1.6e-10 40.8 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KFH42415.1 - 8.5e-09 34.7 0.1 2.2e-05 23.5 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KFH42415.1 - 0.019 13.8 0.0 0.083 11.7 0.0 2.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase DUF1640 PF07798.6 KFH42416.1 - 6.4e-62 208.7 5.7 4.6e-52 176.6 2.4 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1640) Lzipper-MIP1 PF14389.1 KFH42416.1 - 0.014 15.5 3.7 2.1 8.5 0.0 2.6 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 cwf21 PF08312.7 KFH42416.1 - 0.03 14.1 5.8 0.38 10.6 2.8 2.8 2 1 0 2 2 2 0 cwf21 domain Syntaxin PF00804.20 KFH42416.1 - 1.4 9.1 7.2 12 6.0 5.0 2.2 1 1 0 1 1 1 0 Syntaxin WD40 PF00400.27 KFH42418.1 - 1.9e-56 186.0 25.4 7.5e-11 41.4 0.3 8.2 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 KFH42418.1 - 6e-12 45.1 1.7 1.2e-11 44.1 1.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFH42418.1 - 2.4e-11 42.9 1.5 5.7e-11 41.7 1.0 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 KFH42418.1 - 3.4e-09 35.3 3.4 0.084 10.9 0.0 4.2 2 1 2 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFH42418.1 - 0.0092 14.7 2.1 0.43 9.2 0.1 2.4 1 1 1 2 2 2 2 Nup133 N terminal like Abhydrolase_6 PF12697.2 KFH42419.1 - 3.1e-30 105.7 0.9 5e-30 105.0 0.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH42419.1 - 2.8e-11 43.3 0.0 7.5e-11 41.9 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFH42419.1 - 0.0062 16.1 0.0 0.0099 15.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFH42419.1 - 0.059 12.5 0.0 4.5 6.4 0.0 3.0 3 1 0 3 3 3 0 Prolyl oligopeptidase family DUF3089 PF11288.3 KFH42419.1 - 0.086 11.9 0.0 0.2 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) FSH1 PF03959.8 KFH42419.1 - 0.11 11.9 0.0 0.32 10.4 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) HAUS6_N PF14661.1 KFH42420.1 - 1.8e-59 201.0 3.5 3.4e-59 200.1 2.4 1.4 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus Ribosomal_S17e PF00833.13 KFH42421.1 - 1.5e-56 189.3 0.1 1.8e-56 189.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 KFH42421.1 - 0.018 15.7 0.0 0.026 15.2 0.0 1.2 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal DUF2196 PF09962.4 KFH42422.1 - 8.6e-23 79.8 1.7 1.3e-22 79.3 1.2 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) zf-Di19 PF05605.7 KFH42422.1 - 0.12 12.5 0.1 0.17 12.0 0.1 1.2 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding TCTP PF00838.12 KFH42423.1 - 2.6e-64 216.1 3.9 2.9e-64 216.0 2.7 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Mus7 PF09462.5 KFH42423.1 - 0.086 11.6 0.0 0.088 11.6 0.0 1.0 1 0 0 1 1 1 0 Mus7/MMS22 family NDUF_B4 PF07225.7 KFH42424.1 - 0.01 15.6 0.2 0.011 15.4 0.1 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) DUF2944 PF11161.3 KFH42424.1 - 0.11 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) SSrecog PF03531.9 KFH42425.1 - 1.5e-72 243.5 0.1 1.2e-71 240.5 0.1 2.1 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 KFH42425.1 - 1.2e-24 86.1 0.1 8.7e-24 83.3 0.0 2.3 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Cwf_Cwc_15 PF04889.7 KFH42425.1 - 0.96 9.1 16.5 2 8.0 11.5 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Mis12 PF05859.7 KFH42426.1 - 5.3e-31 107.3 0.0 9.9e-31 106.4 0.0 1.5 1 0 0 1 1 1 1 Mis12 protein YL1 PF05764.8 KFH42427.1 - 1.2e-59 201.8 31.5 1.2e-59 201.8 21.8 2.8 3 0 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.6 KFH42427.1 - 3.6e-14 52.0 0.2 6.3e-14 51.2 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain GST_N_2 PF13409.1 KFH42428.1 - 7.4e-07 29.0 0.0 1.6e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFH42428.1 - 2.2e-06 27.4 0.7 5.1e-06 26.2 0.5 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KFH42428.1 - 2.7e-06 27.4 0.0 4.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KFH42428.1 - 3.9e-06 26.9 0.1 1.6e-05 24.9 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFH42428.1 - 0.002 18.0 0.0 0.0039 17.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFH42428.1 - 0.0061 17.0 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PBD PF00786.23 KFH42429.1 - 0.00016 21.9 0.5 0.0028 18.0 0.0 2.8 2 0 0 2 2 2 1 P21-Rho-binding domain Alg6_Alg8 PF03155.10 KFH42430.1 - 1.2e-140 469.4 28.0 1.6e-140 469.0 19.4 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Mg_trans_NIPA PF05653.9 KFH42431.1 - 1.6e-59 201.3 5.2 5.1e-57 193.1 1.2 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 KFH42431.1 - 0.00031 20.9 0.4 0.00031 20.9 0.3 3.6 3 1 0 3 3 3 1 Multidrug resistance efflux transporter DUF4131 PF13567.1 KFH42431.1 - 0.0082 15.5 8.0 0.68 9.3 0.1 3.7 1 1 2 3 3 3 1 Domain of unknown function (DUF4131) LRR19-TM PF15176.1 KFH42431.1 - 0.076 12.7 0.0 0.54 9.9 0.0 2.4 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain YfhO PF09586.5 KFH42431.1 - 0.078 10.9 2.8 0.11 10.4 1.9 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO EamA PF00892.15 KFH42431.1 - 0.13 12.2 25.0 0.028 14.4 0.9 4.1 3 1 1 4 4 4 0 EamA-like transporter family DUF914 PF06027.7 KFH42431.1 - 0.38 9.5 5.6 0.21 10.3 0.5 2.2 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF914) Peptidase_M24 PF00557.19 KFH42432.1 - 8.8e-61 205.0 0.1 1.3e-60 204.5 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KFH42432.1 - 6.7e-19 67.6 0.0 1.2e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain RRM_1 PF00076.17 KFH42433.1 - 3.8e-64 212.2 0.1 3e-20 71.6 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH42433.1 - 2.9e-49 164.9 0.0 2.8e-16 59.2 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH42433.1 - 1.9e-21 75.6 0.0 6.9e-08 32.2 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4242 PF14026.1 KFH42433.1 - 0.051 13.6 0.0 1.2 9.2 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4242) Gti1_Pac2 PF09729.4 KFH42434.1 - 2.5e-54 183.6 0.0 3.6e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 Gti1/Pac2 family PRP4 PF08799.6 KFH42435.1 - 8.1e-12 44.1 0.5 8.1e-12 44.1 0.3 2.9 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like Prp18 PF02840.10 KFH42435.1 - 2.3e-07 30.7 0.1 2.3e-07 30.7 0.1 1.9 2 0 0 2 2 2 1 Prp18 domain CDC27 PF09507.5 KFH42435.1 - 0.096 11.8 14.0 0.14 11.3 9.7 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ycf1 PF05758.7 KFH42435.1 - 2.3 5.8 5.3 2.1 5.9 3.7 1.1 1 0 0 1 1 1 0 Ycf1 U79_P34 PF03064.11 KFH42435.1 - 6.1 6.2 12.9 11 5.4 8.9 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF694 PF05107.7 KFH42435.1 - 6.9 5.8 9.0 12 5.0 6.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF694) Phosphodiest PF01663.17 KFH42436.1 - 1e-13 51.3 1.4 4e-12 46.1 1.0 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KFH42436.1 - 2.4e-05 23.6 0.0 4.1e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 KFH42436.1 - 4.2e-05 23.0 0.0 7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF229 PF02995.12 KFH42436.1 - 0.035 12.5 0.1 0.05 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) PINIT PF14324.1 KFH42437.1 - 1.9e-40 138.2 0.1 3.2e-40 137.5 0.1 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 KFH42437.1 - 1.1e-20 72.8 3.1 1.1e-20 72.8 2.1 1.7 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KFH42437.1 - 9.4e-07 28.2 0.3 2.8e-06 26.7 0.2 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.22 KFH42437.1 - 1.7e-05 24.1 0.0 3.6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 SAP domain zf-Sec23_Sec24 PF04810.10 KFH42437.1 - 0.0059 16.1 0.9 0.014 14.9 0.1 2.0 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger PROCN PF08083.6 KFH42438.1 - 1.3e-221 735.2 7.2 2.1e-221 734.5 5.0 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 KFH42438.1 - 4e-125 415.7 1.3 7.1e-125 414.8 0.9 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 KFH42438.1 - 3.5e-92 305.9 0.8 7.4e-92 304.9 0.5 1.6 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 KFH42438.1 - 9e-77 255.9 4.0 1.5e-76 255.2 1.8 2.1 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 KFH42438.1 - 3.6e-66 220.8 0.1 7.7e-66 219.8 0.0 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 KFH42438.1 - 1.2e-43 147.7 0.2 3.2e-43 146.4 0.0 1.9 2 0 0 2 2 2 1 PROCT (NUC072) domain RRM_4 PF10598.4 KFH42438.1 - 1.3e-42 143.5 0.0 3.3e-42 142.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 DUF3753 PF12575.3 KFH42438.1 - 0.061 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) OCD_Mu_crystall PF02423.10 KFH42438.1 - 0.3 9.7 0.9 0.69 8.6 0.6 1.5 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Peptidase_S64 PF08192.6 KFH42439.1 - 7.7 4.7 7.3 10 4.3 5.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 PPR_2 PF13041.1 KFH42440.1 - 1.7e-16 59.8 0.0 4.4e-07 29.7 0.0 6.8 6 1 1 7 7 7 3 PPR repeat family PPR_3 PF13812.1 KFH42440.1 - 1.1e-06 28.3 1.0 1.9 8.9 0.0 6.2 6 0 0 6 6 6 1 Pentatricopeptide repeat domain PPR PF01535.15 KFH42440.1 - 1.2e-06 28.0 0.9 2.5 8.2 0.0 5.6 5 1 0 5 5 5 2 PPR repeat PPR_1 PF12854.2 KFH42440.1 - 0.023 14.1 0.6 3.2 7.3 0.0 4.0 4 0 0 4 4 4 0 PPR repeat BTAD PF03704.12 KFH42440.1 - 0.029 14.6 1.8 0.42 10.9 0.0 3.1 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TPR_14 PF13428.1 KFH42440.1 - 0.06 13.9 4.5 31 5.5 0.1 4.9 3 1 1 4 4 4 0 Tetratricopeptide repeat Pox_Ag35 PF03286.9 KFH42440.1 - 0.069 12.6 5.1 0.22 11.0 0.0 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein SAP18 PF06487.7 KFH42441.1 - 1.2e-16 60.5 0.0 1.5e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) FA_hydroxylase PF04116.8 KFH42442.1 - 4.5e-19 68.9 10.7 4.5e-19 68.9 7.4 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily WAC_Acf1_DNA_bd PF10537.4 KFH42443.1 - 4.5e-22 78.1 1.5 6.4e-22 77.6 0.0 2.2 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 KFH42443.1 - 1.5e-16 59.8 0.6 3e-16 58.9 0.4 1.5 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 KFH42443.1 - 7.2e-14 51.0 0.5 1.5e-13 50.0 0.3 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 KFH42443.1 - 8e-05 22.3 0.5 0.0004 20.1 0.4 2.2 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 WHIM1 PF15612.1 KFH42443.1 - 0.00011 21.9 1.9 0.00013 21.6 0.1 2.2 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 MFS_3 PF05977.8 KFH42443.1 - 0.35 8.9 0.2 0.6 8.1 0.2 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector Lipase_3 PF01764.20 KFH42444.1 - 7.9e-08 32.0 0.0 1.6e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KFH42444.1 - 0.03 14.0 0.0 0.056 13.1 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.7 KFH42444.1 - 0.065 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Lectin_leg-like PF03388.8 KFH42445.1 - 4.2e-24 84.9 0.0 7e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 Legume-like lectin family Med4 PF10018.4 KFH42445.1 - 0.015 14.7 1.3 0.026 13.9 0.7 1.5 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Syntaxin PF00804.20 KFH42445.1 - 0.015 15.4 3.8 0.028 14.6 2.6 1.4 1 0 0 1 1 1 0 Syntaxin FUSC PF04632.7 KFH42445.1 - 0.02 13.3 0.3 0.028 12.8 0.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family TMF_TATA_bd PF12325.3 KFH42445.1 - 0.03 14.0 4.3 0.029 14.1 1.7 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Macoilin PF09726.4 KFH42445.1 - 0.046 12.0 5.1 0.063 11.5 3.6 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF848 PF05852.6 KFH42445.1 - 0.068 13.0 2.2 0.11 12.2 1.6 1.3 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DivIC PF04977.10 KFH42445.1 - 0.073 12.5 3.1 1.1 8.7 2.1 2.6 1 1 0 1 1 1 0 Septum formation initiator DUF1319 PF07028.6 KFH42445.1 - 0.078 13.1 2.6 0.14 12.3 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) Spc7 PF08317.6 KFH42445.1 - 0.084 11.5 2.7 0.12 10.9 1.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Syntaxin-6_N PF09177.6 KFH42445.1 - 0.12 12.7 2.4 0.4 11.1 1.7 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF4391 PF14335.1 KFH42445.1 - 0.12 11.7 0.7 0.19 11.1 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) Ead_Ea22 PF13935.1 KFH42445.1 - 0.16 12.2 1.5 0.3 11.4 1.1 1.4 1 1 0 1 1 1 0 Ead/Ea22-like protein IncA PF04156.9 KFH42445.1 - 0.2 11.2 10.2 0.84 9.2 7.1 1.8 1 1 1 2 2 2 0 IncA protein Fib_alpha PF08702.5 KFH42445.1 - 0.51 10.4 4.2 1 9.4 2.9 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.7 KFH42445.1 - 0.67 9.7 2.9 1.3 8.8 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Occludin_ELL PF07303.8 KFH42445.1 - 0.91 10.2 6.2 4.7 7.9 3.4 2.2 1 1 1 2 2 2 0 Occludin homology domain Pox_A11 PF05061.8 KFH42445.1 - 0.99 8.4 3.6 1.4 7.8 2.5 1.1 1 0 0 1 1 1 0 Poxvirus A11 Protein DUF972 PF06156.8 KFH42445.1 - 1.2 9.4 4.2 2.3 8.6 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) ATG16 PF08614.6 KFH42445.1 - 1.4 8.7 10.1 6.3 6.5 7.0 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Pox_A_type_inc PF04508.7 KFH42445.1 - 1.9 8.5 5.6 0.82 9.6 0.6 2.7 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Striatin PF08232.7 KFH42445.1 - 5.3 7.3 10.2 0.59 10.4 2.8 2.1 1 1 1 2 2 2 0 Striatin family Fungal_trans PF04082.13 KFH42447.1 - 2.2e-32 111.9 0.7 3.4e-32 111.3 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH42447.1 - 8.5e-11 41.5 13.6 1.6e-10 40.7 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fer2 PF00111.22 KFH42447.1 - 0.17 11.6 2.2 1.7 8.4 0.0 2.4 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Galactosyl_T PF01762.16 KFH42448.1 - 0.13 11.8 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Galactosyltransferase DNA_pol3_tau_4 PF12168.3 KFH42449.1 - 0.011 16.0 0.6 0.028 14.8 0.4 1.6 1 0 0 1 1 1 0 DNA polymerase III subunits tau domain IV DnaB-binding TSA PF03249.8 KFH42449.1 - 1.6 7.1 5.2 2.5 6.5 3.6 1.3 1 0 0 1 1 1 0 Type specific antigen GARS_A PF01071.14 KFH42450.1 - 6.6e-83 277.0 0.0 1.1e-82 276.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 KFH42450.1 - 2.5e-36 124.1 0.0 1.2e-35 121.9 0.0 2.2 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 KFH42450.1 - 8.7e-29 100.5 0.0 2e-28 99.3 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 KFH42450.1 - 6.1e-24 84.0 0.1 2.9e-23 81.8 0.1 2.2 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 KFH42450.1 - 7.9e-17 61.2 1.7 2.9e-16 59.4 0.4 2.4 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 KFH42450.1 - 4.1e-09 36.4 0.0 1.2e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KFH42450.1 - 3.9e-08 32.4 0.0 7.7e-08 31.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KFH42450.1 - 0.00011 21.6 0.0 0.00026 20.4 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 KFH42450.1 - 0.00021 20.6 0.1 0.00042 19.6 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.9 KFH42450.1 - 0.045 13.6 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_2 PF08442.5 KFH42450.1 - 0.058 12.7 0.1 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain RPN7 PF10602.4 KFH42451.1 - 9.6e-48 161.8 0.0 2.1e-47 160.7 0.0 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 KFH42451.1 - 6.6e-17 61.7 3.3 1.4e-16 60.6 0.0 2.9 3 1 0 3 3 3 1 PCI domain TPR_2 PF07719.12 KFH42451.1 - 0.00014 21.5 2.4 2.6 8.1 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFH42451.1 - 0.098 12.3 0.1 19 5.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFH42451.1 - 0.11 13.2 1.3 17 6.2 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Cnd3 PF12719.2 KFH42452.1 - 8.1e-90 300.8 1.1 4e-89 298.5 0.1 2.6 3 1 1 4 4 4 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 KFH42452.1 - 1.2e-09 38.3 8.7 1.6e-05 25.0 0.3 5.4 3 2 2 5 5 5 3 HEAT repeats HEAT PF02985.17 KFH42452.1 - 3.7e-07 29.6 6.0 0.15 12.1 0.0 7.0 6 0 0 6 6 6 1 HEAT repeat MMS19_N PF14500.1 KFH42452.1 - 0.015 14.5 0.2 0.67 9.1 0.1 3.1 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.1 KFH42452.1 - 0.023 15.2 7.8 0.64 10.5 0.8 5.4 2 2 2 4 4 4 0 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KFH42452.1 - 0.052 13.9 0.0 0.39 11.1 0.0 2.5 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region DUF1546 PF07571.8 KFH42452.1 - 0.18 11.9 2.4 0.39 10.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1546) DUF2423 PF10338.4 KFH42453.1 - 4.4e-15 55.3 3.4 4.4e-15 55.3 2.3 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2423) FAD_binding_3 PF01494.14 KFH42454.1 - 2.5e-12 46.5 1.9 0.00014 21.0 0.2 3.1 3 0 0 3 3 3 3 FAD binding domain Pyr_redox PF00070.22 KFH42454.1 - 6.8e-06 26.4 0.3 1.8e-05 25.0 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFH42454.1 - 4.2e-05 23.4 0.2 0.00011 22.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KFH42454.1 - 8.3e-05 21.6 0.3 0.00021 20.2 0.2 1.6 1 1 1 2 2 2 1 FAD binding domain DAO PF01266.19 KFH42454.1 - 0.0001 21.3 0.8 0.00052 19.0 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KFH42454.1 - 0.0001 20.8 0.5 0.00016 20.2 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.19 KFH42454.1 - 0.0012 17.9 0.0 0.002 17.2 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 KFH42454.1 - 0.0037 17.1 0.1 0.01 15.6 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KFH42454.1 - 0.0075 15.3 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 KFH42454.1 - 0.03 13.3 0.2 0.26 10.3 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.1 KFH42454.1 - 0.038 14.0 0.0 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase BAR PF03114.13 KFH42455.1 - 4.3e-64 216.1 4.6 5.1e-64 215.9 3.2 1.1 1 0 0 1 1 1 1 BAR domain Pept_tRNA_hydro PF01195.14 KFH42456.1 - 7.4e-29 100.5 0.0 8.8e-29 100.2 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PLDc_2 PF13091.1 KFH42458.1 - 1.6e-17 63.4 0.0 1.6e-10 40.7 0.0 2.4 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KFH42458.1 - 0.00034 20.3 0.1 0.026 14.3 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Zn_clus PF00172.13 KFH42459.1 - 1.3e-10 40.9 10.9 2.1e-10 40.3 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFH42459.1 - 9.2e-10 37.8 1.2 3.2e-09 36.0 0.8 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain TauD PF02668.11 KFH42460.1 - 1.3e-53 182.3 0.2 1.6e-53 182.0 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Ribosomal_L13 PF00572.13 KFH42461.1 - 9.9e-28 96.7 0.0 1.9e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 DSBA PF01323.15 KFH42461.1 - 0.06 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 DSBA-like thioredoxin domain TauD PF02668.11 KFH42462.1 - 1.5e-27 96.9 0.6 1.9e-27 96.5 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KFH42462.1 - 0.019 13.8 0.1 0.032 13.1 0.1 1.3 1 0 0 1 1 1 0 CsiD 2OG-FeII_Oxy_3 PF13640.1 KFH42462.1 - 0.11 12.9 0.3 0.32 11.5 0.2 1.9 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DEC-1_N PF04625.8 KFH42463.1 - 6.7 5.2 9.1 1.4 7.5 3.0 1.9 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Adap_comp_sub PF00928.16 KFH42464.1 - 1.2e-84 283.5 0.0 1.6e-84 283.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KFH42464.1 - 2e-05 24.3 0.2 3.6e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF2305 PF10230.4 KFH42465.1 - 2.5e-60 204.1 0.0 2.9e-60 203.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 KFH42465.1 - 2.4e-06 27.6 3.5 3.2e-06 27.1 2.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KFH42465.1 - 0.005 16.4 0.1 0.01 15.4 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFH42465.1 - 0.02 14.6 0.0 0.036 13.8 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.11 KFH42466.1 - 2.5e-40 138.2 51.3 2.5e-40 138.2 35.6 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KFH42466.1 - 3e-16 58.7 12.8 5.1e-16 58.0 8.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KFH42466.1 - 6.8e-14 51.2 13.5 6.8e-14 51.2 9.4 4.2 2 2 0 4 4 4 1 Sugar (and other) transporter DUF2614 PF11023.3 KFH42466.1 - 1.8 8.3 5.4 0.27 11.0 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2614) BAR PF03114.13 KFH42468.1 - 1.8e-44 151.9 5.4 2.1e-44 151.7 3.8 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 KFH42468.1 - 1e-06 27.8 1.2 1.3e-06 27.6 0.8 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Myosin_tail_1 PF01576.14 KFH42468.1 - 0.0051 14.6 8.5 0.0076 14.0 5.9 1.1 1 0 0 1 1 1 1 Myosin tail DUF4378 PF14309.1 KFH42468.1 - 0.14 12.2 0.8 0.26 11.3 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) Arfaptin PF06456.8 KFH42468.1 - 0.3 10.4 6.3 0.81 8.9 2.8 2.3 2 1 0 2 2 2 0 Arfaptin-like domain Atg14 PF10186.4 KFH42468.1 - 0.34 9.7 2.0 0.45 9.4 1.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 KFH42468.1 - 6.2 5.7 8.1 10 5.0 5.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 KFH42468.1 - 9.4 5.7 8.5 4.2 6.9 4.2 1.5 2 0 0 2 2 2 0 IncA protein Exo_endo_phos PF03372.18 KFH42469.1 - 1.3e-18 67.8 2.4 2.4e-18 66.9 1.7 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ammonium_transp PF00909.16 KFH42470.1 - 1.3e-117 392.6 26.3 1.5e-117 392.4 18.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family EVC2_like PF12297.3 KFH42470.1 - 0.13 10.8 0.0 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Cyclin_N PF00134.18 KFH42471.1 - 0.0014 18.2 0.0 0.0025 17.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain 5_3_exonuc_N PF02739.11 KFH42471.1 - 0.1 11.9 0.1 0.76 9.1 0.0 2.0 2 0 0 2 2 2 0 5'-3' exonuclease, N-terminal resolvase-like domain Sugar_tr PF00083.19 KFH42472.1 - 5.3e-72 242.8 25.8 6.1e-72 242.6 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH42472.1 - 2.2e-21 76.0 30.7 5.7e-19 68.0 13.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 KFH42472.1 - 0.01 14.0 0.2 0.01 14.0 0.2 1.7 2 0 0 2 2 2 0 Transmembrane secretion effector Chalcone PF02431.10 KFH42473.1 - 2.2e-57 193.6 0.0 3e-57 193.2 0.0 1.2 1 0 0 1 1 1 1 Chalcone-flavanone isomerase TRF PF08558.5 KFH42473.1 - 0.049 12.9 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Telomere repeat binding factor (TRF) DUF4234 PF14018.1 KFH42473.1 - 0.07 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) GMC_oxred_N PF00732.14 KFH42474.1 - 2.1e-63 214.2 0.0 2.8e-63 213.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFH42474.1 - 2.7e-24 86.1 0.0 5.4e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KFH42474.1 - 2.2e-06 26.7 1.3 0.028 13.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KFH42474.1 - 2.1e-05 23.6 0.1 3.2e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KFH42474.1 - 0.00033 19.6 1.0 0.0066 15.4 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFH42474.1 - 0.0044 17.0 0.1 0.012 15.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFH42474.1 - 0.0066 16.3 0.0 0.053 13.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KFH42474.1 - 0.0075 14.9 0.1 0.011 14.3 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase FAD_binding_3 PF01494.14 KFH42474.1 - 0.051 12.6 0.2 1.3 7.9 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Mqo PF06039.10 KFH42474.1 - 0.052 11.7 0.0 0.72 7.9 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) DCP1 PF06058.8 KFH42475.1 - 1.4e-14 54.2 0.0 2.3e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family CMD PF02627.15 KFH42476.1 - 0.09 12.6 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family Abhydrolase_3 PF07859.8 KFH42477.1 - 4e-34 118.0 0.0 3.7e-33 114.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KFH42477.1 - 0.0018 16.9 0.0 0.0029 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 KFH42478.1 - 1.4e-37 129.7 0.1 1.6e-37 129.5 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH42478.1 - 4.1e-14 52.5 0.0 6e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFH42478.1 - 1.6e-12 47.4 0.0 1e-11 44.8 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KFH42478.1 - 0.00034 20.3 0.0 0.00065 19.5 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 KFH42478.1 - 0.11 10.9 0.0 0.18 10.2 0.0 1.4 1 0 0 1 1 1 0 Ndr family GST_C_2 PF13410.1 KFH42479.1 - 0.0032 17.3 0.2 0.0058 16.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFH42479.1 - 0.0096 15.8 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain BAG PF02179.11 KFH42481.1 - 2.9e-19 68.9 0.6 6e-19 67.9 0.4 1.5 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 KFH42481.1 - 9.5e-06 24.9 0.0 2.3e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family TPR_11 PF13414.1 KFH42482.1 - 1.1e-13 50.6 2.4 1.6e-09 37.2 1.3 2.2 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KFH42482.1 - 5.1e-11 41.6 6.0 0.00016 21.3 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KFH42482.1 - 7.9e-09 34.7 1.9 0.0086 15.6 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFH42482.1 - 2e-07 30.8 0.8 0.00025 20.9 0.0 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFH42482.1 - 2.3e-05 24.6 7.6 0.0026 18.2 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFH42482.1 - 2.9e-05 24.5 7.1 0.0011 19.6 0.2 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFH42482.1 - 3.4e-05 24.0 4.3 0.0005 20.3 0.0 3.0 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFH42482.1 - 0.00035 20.1 0.4 0.4 10.5 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 KFH42482.1 - 0.002 18.2 0.1 0.004 17.2 0.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KFH42482.1 - 0.0044 16.8 5.1 4.4 7.2 0.1 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFH42482.1 - 0.35 11.4 7.8 1.5 9.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 KFH42482.1 - 0.46 11.0 6.8 0.67 10.5 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat Zn_clus PF00172.13 KFH42485.1 - 0.092 12.6 5.6 0.21 11.4 3.9 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M28 PF04389.12 KFH42487.1 - 5.9e-33 114.1 0.1 7.5e-32 110.5 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 KFH42487.1 - 8.1e-05 22.2 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nic96 PF04097.9 KFH42487.1 - 0.14 10.2 0.0 0.21 9.6 0.0 1.1 1 0 0 1 1 1 0 Nup93/Nic96 Peptidase_M42 PF05343.9 KFH42487.1 - 0.22 10.2 0.0 0.36 9.5 0.0 1.2 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase zf-CCHC PF00098.18 KFH42488.1 - 1.4e-11 43.7 10.3 1.7e-05 24.5 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 KFH42488.1 - 9.2e-09 34.8 0.2 1.7e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 KFH42488.1 - 9e-07 28.5 5.9 0.00029 20.5 2.0 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_3 PF13014.1 KFH42488.1 - 9.6e-06 25.1 0.2 2.3e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_4 PF14392.1 KFH42488.1 - 0.00097 18.7 6.3 0.22 11.2 0.6 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 KFH42488.1 - 0.008 15.8 10.7 0.14 11.8 0.3 2.7 2 1 1 3 3 3 2 Zinc knuckle Lipase_3 PF01764.20 KFH42489.1 - 2.2e-18 66.2 0.0 4.2e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Glyco_hydro_88 PF07470.8 KFH42490.1 - 2e-12 46.8 0.1 6.4e-11 41.8 0.1 2.2 2 0 0 2 2 2 2 Glycosyl Hydrolase Family 88 F-box-like PF12937.2 KFH42491.1 - 1.1e-13 50.6 1.6 3.4e-13 49.0 0.8 2.1 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.1 KFH42491.1 - 2.7e-07 29.9 29.1 2.1 8.6 0.0 11.9 12 1 0 12 12 12 2 Leucine Rich repeat LRR_8 PF13855.1 KFH42491.1 - 8.3e-06 25.4 20.1 0.038 13.7 0.7 5.8 3 1 4 7 7 7 5 Leucine rich repeat F-box PF00646.28 KFH42491.1 - 0.00043 19.8 0.5 0.00043 19.8 0.3 2.7 2 1 0 2 2 2 1 F-box domain DUF1699 PF08004.6 KFH42491.1 - 0.034 13.6 1.6 2.4 7.6 0.0 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1699) LRR_1 PF00560.28 KFH42491.1 - 0.05 13.6 31.4 13 6.2 0.0 10.1 7 4 1 8 8 8 0 Leucine Rich Repeat Fungal_trans PF04082.13 KFH42493.1 - 6.6e-18 64.5 0.1 1.1e-17 63.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glutaredoxin PF00462.19 KFH42494.1 - 1.7e-20 72.7 0.0 2.8e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_9 PF14595.1 KFH42494.1 - 0.0014 18.2 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KFH42494.1 - 0.021 15.0 0.3 0.094 12.9 0.2 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain DUF836 PF05768.9 KFH42494.1 - 0.029 14.6 0.0 0.051 13.8 0.0 1.6 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Peptidase_M24 PF00557.19 KFH42495.1 - 1.9e-20 73.3 0.1 2.8e-20 72.7 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KFH42495.1 - 1e-16 61.6 0.0 2e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Snurportin1 PF11538.3 KFH42495.1 - 0.15 11.8 0.5 0.33 10.7 0.3 1.6 1 0 0 1 1 1 0 Snurportin1 LSM PF01423.17 KFH42496.1 - 3.7e-16 58.4 0.2 4.6e-16 58.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain Glutaminase PF04960.10 KFH42497.1 - 3.1e-101 338.1 0.1 3.8e-101 337.8 0.0 1.1 1 0 0 1 1 1 1 Glutaminase Zip PF02535.17 KFH42498.1 - 7.6e-53 179.5 0.4 9e-53 179.3 0.3 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Ferritin_2 PF13668.1 KFH42499.1 - 1.2e-07 31.7 0.0 1.9e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Ribosomal_S19e PF01090.14 KFH42500.1 - 8.8e-54 180.7 0.4 1.1e-53 180.4 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Citrate_synt PF00285.16 KFH42501.1 - 3.5e-115 384.5 0.0 4.6e-115 384.1 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Noelin-1 PF12308.3 KFH42501.1 - 0.16 11.8 0.2 5.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Neurogenesis glycoprotein Paf67 PF10255.4 KFH42502.1 - 3.6e-154 513.5 0.7 4.2e-154 513.2 0.5 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 KFH42502.1 - 0.033 14.1 0.0 0.16 11.9 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat PEX11 PF05648.9 KFH42503.1 - 4.5e-32 111.1 0.0 6.8e-32 110.5 0.0 1.2 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) CorA PF01544.13 KFH42504.1 - 1.1 8.2 14.7 21 4.0 10.2 2.6 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Fmp27 PF10344.4 KFH42505.1 - 1e-210 701.8 0.0 7e-210 699.0 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 KFH42505.1 - 1.4e-161 538.3 0.6 3.2e-161 537.2 0.4 1.7 1 0 0 1 1 1 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 KFH42505.1 - 5.3e-154 513.1 0.3 1.2e-153 512.0 0.0 1.7 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 KFH42505.1 - 1.6e-53 180.7 0.0 3.7e-53 179.6 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 KFH42505.1 - 1.2e-52 177.7 0.2 3e-52 176.5 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 KFH42505.1 - 3e-29 101.4 0.0 9.1e-29 99.9 0.0 1.9 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Dynamin_N PF00350.18 KFH42507.1 - 6.6e-30 104.1 0.0 1.4e-29 103.1 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KFH42507.1 - 2.3e-22 79.1 0.3 2.6e-19 69.1 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 KFH42507.1 - 0.0045 16.9 0.0 0.035 14.0 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RTX_C PF08339.5 KFH42507.1 - 0.025 14.2 0.1 0.055 13.1 0.1 1.5 1 0 0 1 1 1 0 RTX C-terminal domain Miro PF08477.8 KFH42507.1 - 0.027 14.9 0.0 0.084 13.3 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein ABA_GPCR PF12430.3 KFH42508.1 - 1.8e-42 144.7 1.1 3.1e-42 143.9 0.0 1.9 3 0 0 3 3 3 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 KFH42508.1 - 8.4e-19 67.3 0.0 2.4e-18 65.9 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3735) CagY_I PF14585.1 KFH42509.1 - 0.084 12.8 2.4 0.16 11.9 1.7 1.5 1 0 0 1 1 1 0 CagY type 1 repeat Fungal_trans_2 PF11951.3 KFH42511.1 - 7.9e-08 31.3 1.5 0.0017 17.0 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Beta_elim_lyase PF01212.16 KFH42513.1 - 3.3e-73 246.3 0.0 4.2e-73 246.0 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 KFH42513.1 - 0.033 12.4 0.0 0.05 11.8 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme EthD PF07110.6 KFH42514.1 - 3.4e-13 50.3 0.2 4.7e-13 49.8 0.1 1.2 1 0 0 1 1 1 1 EthD domain DUF4372 PF14294.1 KFH42514.1 - 0.12 12.2 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4372) JAB PF01398.16 KFH42515.1 - 4.6e-28 97.2 0.0 7.4e-28 96.5 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 KFH42515.1 - 3.6e-08 32.9 0.0 6.6e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain FAD_binding_4 PF01565.18 KFH42516.1 - 3e-18 65.6 1.8 1.2e-17 63.6 0.4 2.3 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KFH42516.1 - 1e-06 28.5 0.0 2.1e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like VGCC_alpha2 PF08473.6 KFH42516.1 - 0.024 14.3 0.0 0.053 13.2 0.0 1.5 1 0 0 1 1 1 0 Neuronal voltage-dependent calcium channel alpha 2acd KH_1 PF00013.24 KFH42517.1 - 3.6 7.3 7.8 7.9 6.2 0.0 4.3 4 0 0 4 4 4 0 KH domain FAD_binding_4 PF01565.18 KFH42518.1 - 2.9e-21 75.4 1.4 5.8e-21 74.4 1.0 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFH42518.1 - 4.2e-10 39.3 0.6 8.1e-10 38.4 0.4 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KFH42518.1 - 0.0012 18.0 0.0 0.0018 17.4 0.0 1.2 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding Secretin_N_2 PF07655.8 KFH42518.1 - 2.6 8.4 16.6 5.5 7.4 11.5 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain DUF912 PF06024.7 KFH42518.1 - 7 6.7 7.3 11 6.0 5.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) GTP_EFTU PF00009.22 KFH42519.1 - 3.7e-53 179.7 0.0 6.7e-53 178.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 KFH42519.1 - 4e-16 58.6 0.0 1e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KFH42519.1 - 2.3e-09 37.2 0.0 8.1e-09 35.4 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KFH42519.1 - 3.5e-07 29.9 0.0 8.3e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 KFH42519.1 - 5e-07 29.3 0.0 0.00027 20.5 0.0 2.8 3 0 0 3 3 3 2 Elongation factor G, domain IV MMR_HSR1 PF01926.18 KFH42519.1 - 0.0042 17.0 0.0 0.012 15.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase XLF PF09302.6 KFH42519.1 - 0.08 12.7 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 XLF (XRCC4-like factor) DUF952 PF06108.7 KFH42519.1 - 0.09 12.6 0.0 0.27 11.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF952) Abhydrolase_3 PF07859.8 KFH42520.1 - 6.2e-53 179.5 0.0 7.8e-53 179.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KFH42520.1 - 1.2e-07 30.8 0.0 2.5e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 KFH42520.1 - 5.1e-07 29.7 0.1 8.2e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH42520.1 - 9.9e-06 25.3 0.0 1.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFH42520.1 - 9.6e-05 21.7 0.0 0.00023 20.4 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 KFH42520.1 - 0.0027 17.0 0.1 0.11 11.8 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.7 KFH42520.1 - 0.019 13.4 0.1 0.031 12.7 0.1 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.4 KFH42520.1 - 0.042 13.0 0.0 0.082 12.1 0.0 1.5 1 0 0 1 1 1 0 Esterase PHB depolymerase CFEM PF05730.6 KFH42521.1 - 8e-05 22.3 5.6 0.00013 21.6 3.9 1.4 1 0 0 1 1 1 1 CFEM domain Plasmodium_Vir PF05795.6 KFH42521.1 - 0.095 11.8 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Glyco_hydro_61 PF03443.9 KFH42522.1 - 1.9e-66 223.9 0.1 2.2e-66 223.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 RRM_6 PF14259.1 KFH42523.1 - 1.7e-13 50.3 0.0 2.8e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFH42523.1 - 1.1e-12 47.4 0.0 1.9e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH42523.1 - 4.6e-06 26.3 0.0 7.8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spore_coat_CotO PF14153.1 KFH42523.1 - 4.5 6.6 13.3 8.4 5.7 9.2 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Usp PF00582.21 KFH42524.1 - 1.8e-11 44.4 6.0 7.9e-05 22.8 0.1 3.6 3 1 1 4 4 4 2 Universal stress protein family DUF4449 PF14613.1 KFH42525.1 - 1.4e-64 216.9 1.6 1.4e-64 216.9 1.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) adh_short PF00106.20 KFH42526.1 - 3e-25 89.0 2.1 3.5e-24 85.5 1.4 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH42526.1 - 2.6e-18 66.6 2.8 1.2e-17 64.4 2.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH42526.1 - 5.3e-10 39.2 1.8 8e-10 38.6 0.1 1.9 1 1 1 2 2 2 1 KR domain Shikimate_DH PF01488.15 KFH42526.1 - 0.00012 22.2 0.6 0.0003 20.9 0.4 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 KFH42526.1 - 0.0064 16.7 0.8 0.05 13.8 0.6 2.4 1 1 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox PF00070.22 KFH42526.1 - 0.0078 16.5 0.1 0.019 15.3 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.21 KFH42526.1 - 0.01 15.3 0.2 0.021 14.3 0.2 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Saccharop_dh PF03435.13 KFH42526.1 - 0.011 14.7 0.7 0.012 14.5 0.1 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase DUF162 PF02589.10 KFH42526.1 - 0.011 15.2 0.4 0.023 14.2 0.3 1.5 1 0 0 1 1 1 0 Uncharacterised ACR, YkgG family COG1556 NAD_binding_10 PF13460.1 KFH42526.1 - 0.015 15.3 3.5 0.28 11.1 2.4 2.3 1 1 0 1 1 1 0 NADH(P)-binding 3HCDH_N PF02737.13 KFH42526.1 - 0.023 14.3 0.9 0.058 13.0 0.2 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 KFH42526.1 - 0.053 12.4 0.1 0.13 11.1 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DUF1776 PF08643.5 KFH42526.1 - 0.062 12.4 0.0 0.13 11.4 0.0 1.7 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF2562 PF10814.3 KFH42526.1 - 0.066 13.1 0.9 0.13 12.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2562) Epimerase PF01370.16 KFH42526.1 - 0.079 12.3 0.4 0.84 9.0 0.0 2.5 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family HrpB7 PF09486.5 KFH42526.1 - 0.23 11.3 1.6 0.39 10.6 0.1 2.0 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) adh_short PF00106.20 KFH42527.1 - 1.7e-12 47.6 0.0 2.9e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH42527.1 - 0.00019 21.1 0.1 0.00036 20.2 0.0 1.5 2 0 0 2 2 2 1 KR domain DUF3940 PF13076.1 KFH42527.1 - 0.052 13.1 0.3 0.093 12.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3940) DUF3818 PF12825.2 KFH42528.1 - 1.6e-36 125.6 0.0 1.8e-26 92.6 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 KFH42528.1 - 5.8e-28 97.2 0.0 1.2e-27 96.1 0.0 1.6 1 0 0 1 1 1 1 PX-associated IL10 PF00726.12 KFH42528.1 - 0.12 11.7 0.0 0.27 10.5 0.0 1.5 1 0 0 1 1 1 0 Interleukin 10 TSP_1 PF00090.14 KFH42529.1 - 0.064 13.3 3.2 0.17 12.0 2.2 1.7 1 0 0 1 1 1 0 Thrombospondin type 1 domain Peptidase_M20 PF01546.23 KFH42530.1 - 2.2e-24 86.0 0.0 3.2e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KFH42530.1 - 3.3e-13 49.3 0.0 5.5e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KFH42530.1 - 0.099 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 DUF3722 PF12519.3 KFH42531.1 - 1.7e-79 266.7 0.0 2.2e-79 266.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 KFH42531.1 - 0.00065 19.0 0.0 0.048 12.9 0.1 2.4 2 0 0 2 2 2 2 Eukaryotic porin zf-3CxxC PF13695.1 KFH42532.1 - 9.3e-27 93.1 0.5 1.2e-26 92.7 0.4 1.1 1 0 0 1 1 1 1 Zinc-binding domain DUF905 PF06006.7 KFH42533.1 - 0.12 11.7 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF905) NADH-u_ox-rdase PF10785.4 KFH42533.1 - 0.49 10.6 2.5 14 6.0 0.1 3.0 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit OppC_N PF12911.2 KFH42533.1 - 1.2 8.5 4.4 4.3 6.7 0.0 3.4 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C adh_short PF00106.20 KFH42534.1 - 3.1e-25 89.0 1.4 4.6e-25 88.4 0.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH42534.1 - 7.5e-12 45.5 0.0 1.1e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH42534.1 - 1.5e-07 31.2 0.8 2.3e-07 30.6 0.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFH42534.1 - 2.9e-07 30.1 0.1 6.2e-07 29.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFH42534.1 - 2.4e-06 27.6 0.4 4.3e-06 26.8 0.3 1.4 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 KFH42534.1 - 0.0013 17.9 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.8 KFH42534.1 - 0.0082 15.4 0.2 0.014 14.6 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 KFH42534.1 - 0.11 11.3 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KFH42534.1 - 0.23 10.3 1.0 0.56 9.0 0.7 2.0 1 1 0 1 1 1 0 Male sterility protein Sterol_MT_C PF08498.5 KFH42535.1 - 8.5e-29 99.3 0.1 1.4e-28 98.6 0.1 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 KFH42535.1 - 5.1e-22 78.1 0.0 2.5e-21 75.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH42535.1 - 4.2e-18 65.3 0.0 7.5e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFH42535.1 - 7.1e-14 51.9 0.0 1.5e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH42535.1 - 8e-14 51.6 0.1 1.9e-13 50.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFH42535.1 - 5.9e-12 45.1 0.0 1.1e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KFH42535.1 - 1.3e-11 44.1 0.1 2e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 KFH42535.1 - 3.1e-11 43.6 0.0 1.5e-10 41.4 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH42535.1 - 1.2e-10 41.9 0.0 3.1e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFH42535.1 - 5.5e-10 39.2 0.0 2.1e-09 37.3 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KFH42535.1 - 2.4e-05 23.7 0.0 5.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.5 KFH42535.1 - 4e-05 23.2 0.0 6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 KFH42535.1 - 0.00034 19.8 0.1 0.0011 18.1 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 KFH42535.1 - 0.00053 19.5 0.0 0.001 18.6 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_29 PF03141.11 KFH42535.1 - 0.0042 15.4 0.0 0.007 14.7 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.7 KFH42535.1 - 0.0078 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.13 KFH42535.1 - 0.0083 15.3 0.2 0.02 14.0 0.0 1.7 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_32 PF13679.1 KFH42535.1 - 0.014 15.0 0.0 0.033 13.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 KFH42535.1 - 0.016 14.7 0.0 0.053 13.0 0.0 1.8 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_24 PF13578.1 KFH42535.1 - 0.019 15.7 0.1 0.21 12.4 0.0 2.5 3 0 0 3 3 3 0 Methyltransferase domain RrnaAD PF00398.15 KFH42535.1 - 0.02 13.9 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase ABC_membrane PF00664.18 KFH42537.1 - 7e-80 268.3 34.5 2.9e-41 141.7 10.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFH42537.1 - 1.5e-65 219.5 0.0 1.5e-31 109.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KFH42537.1 - 9.9e-12 44.5 0.2 0.00049 19.4 0.0 4.0 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFH42537.1 - 2.6e-11 44.0 0.0 0.046 13.6 0.0 4.6 4 0 0 4 4 4 4 AAA domain AAA_29 PF13555.1 KFH42537.1 - 1.5e-08 33.9 0.5 0.0013 18.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KFH42537.1 - 1.7e-08 33.8 0.1 0.00018 20.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 KFH42537.1 - 2.5e-07 30.8 3.0 7.4e-05 22.8 0.1 2.7 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.4 KFH42537.1 - 1e-06 27.6 0.6 0.04 12.4 0.0 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.1 KFH42537.1 - 1.6e-06 28.2 1.4 0.012 15.7 0.1 3.7 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KFH42537.1 - 8.6e-06 26.5 0.0 0.066 14.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 KFH42537.1 - 3e-05 23.8 0.3 0.17 11.8 0.0 3.8 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 KFH42537.1 - 0.00022 20.6 0.1 0.39 10.0 0.0 2.9 3 0 0 3 3 3 2 AAA domain G-alpha PF00503.15 KFH42537.1 - 0.00077 18.2 0.0 0.1 11.2 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA_33 PF13671.1 KFH42537.1 - 0.0021 17.9 0.0 1.4 8.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KFH42537.1 - 0.0029 17.9 0.1 3.8 7.8 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_23 PF13476.1 KFH42537.1 - 0.0038 17.5 0.0 1.2 9.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KFH42537.1 - 0.0078 16.1 0.9 0.63 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KFH42537.1 - 0.012 15.4 0.0 11 5.9 0.0 4.0 4 0 0 4 4 4 0 AAA domain AAA_5 PF07728.9 KFH42537.1 - 0.029 14.1 0.3 18 5.0 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 KFH42537.1 - 0.035 14.0 0.0 7.3 6.5 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase MobB PF03205.9 KFH42537.1 - 0.036 13.7 0.0 4 7.1 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 KFH42537.1 - 0.042 13.6 0.0 1.7 8.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_10 PF12846.2 KFH42537.1 - 0.048 13.0 0.8 13 5.0 0.1 3.4 3 0 0 3 3 3 0 AAA-like domain APS_kinase PF01583.15 KFH42537.1 - 0.12 12.0 0.1 22 4.6 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase RNA_helicase PF00910.17 KFH42537.1 - 0.17 12.1 0.2 5.5 7.2 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Complex1_LYR PF05347.10 KFH42539.1 - 2.8e-08 33.4 0.1 4e-08 32.9 0.1 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KFH42539.1 - 1.1e-06 28.6 0.4 1.9e-06 27.9 0.3 1.2 1 0 0 1 1 1 1 Complex1_LYR-like DUF924 PF06041.6 KFH42539.1 - 0.021 14.5 0.4 0.025 14.3 0.3 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF924) Complex1_LYR_2 PF13233.1 KFH42539.1 - 0.025 15.0 0.5 0.03 14.7 0.3 1.3 1 1 0 1 1 1 0 Complex1_LYR-like ADH_zinc_N PF00107.21 KFH42540.1 - 1.9e-22 79.2 1.2 2.8e-22 78.6 0.8 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFH42540.1 - 1.8e-21 75.9 0.1 5e-21 74.5 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KFH42540.1 - 2.9e-06 28.1 0.5 4.9e-06 27.4 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Diphtheria_C PF02763.9 KFH42540.1 - 0.043 13.2 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 Diphtheria toxin, C domain Swi3 PF07962.7 KFH42542.1 - 1.1e-26 92.2 0.0 1.8e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Amidase PF01425.16 KFH42543.1 - 2.4e-112 376.0 0.0 2.7e-112 375.8 0.0 1.0 1 0 0 1 1 1 1 Amidase HTH_13 PF11972.3 KFH42543.1 - 0.0063 16.3 0.1 0.015 15.1 0.1 1.6 1 0 0 1 1 1 1 HTH DNA binding domain zf-C2H2_jaz PF12171.3 KFH42544.1 - 1.9e-06 27.8 2.7 2.9e-06 27.2 1.9 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFH42544.1 - 0.00061 19.9 0.9 0.001 19.1 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 KFH42544.1 - 0.0082 16.4 0.1 0.016 15.5 0.1 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 KFH42544.1 - 0.03 14.6 1.1 0.058 13.7 0.8 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 KFH42544.1 - 0.12 12.5 0.2 0.17 11.9 0.1 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) F-box-like PF12937.2 KFH42545.1 - 8.4e-12 44.6 0.6 1.6e-11 43.6 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFH42545.1 - 5.5e-08 32.2 0.1 1.1e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 F-box domain Cadherin_C PF01049.12 KFH42545.1 - 0.039 13.9 2.6 0.074 13.0 1.8 1.4 1 0 0 1 1 1 0 Cadherin cytoplasmic region Ribonuclease_T2 PF00445.13 KFH42546.1 - 1.5e-46 158.3 0.6 2.3e-46 157.8 0.4 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family PEP_mutase PF13714.1 KFH42547.1 - 2.3e-55 187.3 0.3 2.8e-55 187.1 0.2 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 KFH42547.1 - 6.4e-13 47.7 0.3 1e-12 47.1 0.2 1.2 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.10 KFH42547.1 - 0.0075 15.4 0.0 0.04 13.0 0.0 1.9 2 0 0 2 2 2 1 Ketopantoate hydroxymethyltransferase p450 PF00067.17 KFH42548.1 - 2.5e-34 118.6 0.0 2.8e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GRIP PF01465.15 KFH42549.1 - 5.2e-16 57.8 0.0 1.2e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 GRIP domain IncA PF04156.9 KFH42549.1 - 4.3e-06 26.4 164.1 0.0094 15.5 14.6 8.7 2 2 5 8 8 8 6 IncA protein Myosin_tail_1 PF01576.14 KFH42549.1 - 1.8e-05 22.7 172.2 0.0002 19.2 47.5 5.3 2 2 2 4 4 4 3 Myosin tail Phage_GP20 PF06810.6 KFH42549.1 - 0.0007 19.0 6.4 0.0007 19.0 4.5 10.8 3 2 8 11 11 11 3 Phage minor structural protein GP20 YscO PF07321.7 KFH42549.1 - 0.0041 16.9 10.9 0.0041 16.9 7.5 10.3 3 2 6 10 10 9 3 Type III secretion protein YscO GAS PF13851.1 KFH42549.1 - 0.0046 16.1 11.9 0.0046 16.1 8.2 9.9 3 2 6 10 10 10 6 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 KFH42549.1 - 0.017 14.9 163.2 0.75 9.6 1.1 9.5 3 2 5 8 8 8 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 KFH42549.1 - 0.062 12.4 56.8 0.087 11.9 3.5 6.7 4 2 3 7 7 7 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 KFH42549.1 - 0.062 13.0 152.9 0.57 9.9 12.9 9.5 3 2 7 10 10 9 0 TPR/MLP1/MLP2-like protein EzrA PF06160.7 KFH42549.1 - 0.38 8.8 121.4 0.051 11.7 22.1 6.4 3 2 3 6 6 6 0 Septation ring formation regulator, EzrA Filament PF00038.16 KFH42549.1 - 0.9 8.9 143.9 0.62 9.4 32.4 7.7 1 1 3 4 4 3 0 Intermediate filament protein APG6 PF04111.7 KFH42549.1 - 2.9 6.8 148.2 0.31 10.0 13.5 7.6 3 2 4 7 7 7 0 Autophagy protein Apg6 TMF_DNA_bd PF12329.3 KFH42549.1 - 6.2 6.6 183.5 0.18 11.5 3.1 13.3 8 5 5 13 13 12 0 TATA element modulatory factor 1 DNA binding Methyltransf_2 PF00891.13 KFH42551.1 - 2.9e-23 82.3 0.1 2.8e-16 59.4 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase MarR_2 PF12802.2 KFH42551.1 - 0.0015 18.1 0.0 0.0038 16.8 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.1 KFH42551.1 - 0.0096 16.2 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 1 Winged helix DNA-binding domain Rrf2 PF02082.15 KFH42551.1 - 0.032 14.3 0.0 0.097 12.7 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator DSHCT PF08148.7 KFH42552.1 - 5.4e-60 201.7 0.2 9.6e-60 200.8 0.2 1.4 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 KFH42552.1 - 2.2e-20 72.8 0.2 8.1e-20 70.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFH42552.1 - 3e-06 27.0 1.0 5.6e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.1 KFH42552.1 - 9.1e-06 25.0 2.2 0.028 13.6 0.3 2.4 2 0 0 2 2 2 2 rRNA-processing arch domain Cut8_C PF08559.5 KFH42552.1 - 0.014 15.2 0.1 0.05 13.4 0.0 1.9 2 0 0 2 2 2 0 Cut8 six-helix bundle SWIRM PF04433.12 KFH42553.1 - 6.1e-16 58.3 0.0 4.2e-15 55.6 0.0 2.0 2 0 0 2 2 2 1 SWIRM domain Zn_clus PF00172.13 KFH42554.1 - 8.4e-05 22.4 8.8 0.00016 21.4 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFH42554.1 - 0.02 13.7 0.0 0.036 12.9 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain CRAL_TRIO PF00650.15 KFH42555.1 - 1.1e-29 103.0 0.0 1.2e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KFH42555.1 - 0.0016 18.3 0.0 0.0022 17.8 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RRM_5 PF13893.1 KFH42556.1 - 1.2e-08 34.6 0.0 2e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFH42556.1 - 1.3e-08 34.3 0.0 2.5e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH42556.1 - 2.2e-05 24.3 0.0 4.1e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFH42556.1 - 0.0013 18.4 0.1 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KFH42556.1 - 0.024 14.4 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif Transket_pyr PF02779.19 KFH42557.1 - 3e-46 157.1 0.1 6.3e-46 156.1 0.0 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KFH42557.1 - 2e-34 118.2 0.0 5.9e-34 116.6 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain DUF4478 PF14793.1 KFH42558.1 - 0.055 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4478) Phospholip_A2_3 PF09056.6 KFH42560.1 - 4.2e-44 149.3 0.3 5.4e-44 148.9 0.2 1.1 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 DnaJ PF00226.26 KFH42561.1 - 4.4e-21 74.3 1.2 4.4e-21 74.3 0.9 2.4 2 1 0 2 2 2 1 DnaJ domain DUF4551 PF15087.1 KFH42561.1 - 3.9 5.7 8.0 9 4.5 5.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) NADH_u_ox_C PF12853.2 KFH42562.1 - 9.5e-34 115.0 0.1 1.5e-33 114.3 0.1 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit NADH-u_ox-rdase PF10785.4 KFH42562.1 - 1.3e-23 83.0 0.4 2.6e-23 82.0 0.3 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Fungal_trans PF04082.13 KFH42563.1 - 4.1e-11 42.2 0.1 7e-11 41.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH42563.1 - 2.4e-08 33.7 12.4 2.4e-08 33.7 8.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_2 PF07716.10 KFH42564.1 - 9.7e-07 28.5 24.9 7e-05 22.5 17.2 2.4 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KFH42564.1 - 0.074 13.0 24.3 0.67 9.9 16.8 2.2 1 1 0 1 1 1 0 bZIP transcription factor bZIP_Maf PF03131.12 KFH42564.1 - 0.11 12.8 14.1 0.2 11.9 9.8 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor BBS2_C PF14782.1 KFH42564.1 - 0.11 11.0 0.8 0.16 10.4 0.6 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal APG6 PF04111.7 KFH42564.1 - 1.2 8.1 8.6 1.7 7.6 6.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 KFH42564.1 - 3.8 7.0 9.5 6.9 6.2 6.6 1.3 1 0 0 1 1 1 0 IncA protein DUF1691 PF07950.6 KFH42565.1 - 2.8e-39 133.4 4.2 1.5e-23 82.8 1.5 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Peptidase_M43 PF05572.8 KFH42567.1 - 7.4e-13 48.3 0.2 1.4e-12 47.4 0.1 1.5 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 KFH42567.1 - 0.015 15.8 0.1 0.16 12.5 0.0 2.4 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like MFS_1 PF07690.11 KFH42568.1 - 3.1e-29 101.7 22.4 3.1e-29 101.7 15.6 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KFH42568.1 - 0.97 9.2 6.5 0.13 12.0 0.5 2.5 3 0 0 3 3 3 0 MFS_1 like family p450 PF00067.17 KFH42569.1 - 9.8e-33 113.3 0.0 1.3e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Hemerythrin PF01814.18 KFH42569.1 - 0.017 15.2 2.8 0.04 14.0 2.0 1.6 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain DUF2296 PF10058.4 KFH42570.1 - 2.6e-18 65.4 0.1 4.3e-18 64.7 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) p450 PF00067.17 KFH42571.1 - 1e-48 166.0 0.0 2e-48 165.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Na_H_Exchanger PF00999.16 KFH42572.1 - 3e-64 216.9 43.5 4.3e-64 216.4 30.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Snf7 PF03357.16 KFH42573.1 - 1.8e-08 33.9 23.9 2.4e-08 33.5 16.6 1.3 1 0 0 1 1 1 1 Snf7 UPF0262 PF06793.7 KFH42573.1 - 0.0054 16.4 0.4 0.0089 15.7 0.3 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0262) Ist1 PF03398.9 KFH42573.1 - 0.034 13.5 5.2 0.065 12.6 3.6 1.5 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway DUF3962 PF13111.1 KFH42573.1 - 0.066 12.6 0.6 0.087 12.1 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3962) ASL_C PF08328.6 KFH42573.1 - 0.48 10.2 4.9 0.3 10.9 1.8 1.8 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminal DUF1451 PF07295.6 KFH42573.1 - 0.66 9.7 11.0 0.3 10.8 2.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) AAA_16 PF13191.1 KFH42573.1 - 3.2 7.7 9.3 3.3 7.6 2.2 2.1 1 1 1 2 2 2 0 AAA ATPase domain SATase_N PF06426.9 KFH42573.1 - 3.7 7.8 9.1 3.3 8.0 3.3 2.7 1 1 1 2 2 2 0 Serine acetyltransferase, N-terminal Mak16 PF04874.9 KFH42573.1 - 4.2 7.5 6.8 3.6 7.7 1.4 2.3 1 1 1 2 2 2 0 Mak16 protein C-terminal region Fungal_trans PF04082.13 KFH42574.1 - 4.1e-22 78.2 0.1 6.2e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH42574.1 - 4.3e-06 26.5 12.6 6.5e-06 25.9 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KFH42576.1 - 4.7e-41 140.6 42.5 7.2e-36 123.6 19.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH42576.1 - 6.1e-12 44.8 22.0 1.4e-11 43.6 15.3 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KFH42576.1 - 5.3e-05 21.6 1.1 5.3e-05 21.6 0.8 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Myb_DNA-binding PF00249.26 KFH42577.1 - 2.8e-13 49.6 2.2 1.5e-07 31.3 0.6 2.6 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFH42577.1 - 3.1e-11 43.1 2.3 3.3e-06 27.1 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain HTH_38 PF13936.1 KFH42577.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Myb_DNA-bind_6 PF13921.1 KFH42579.1 - 7.6e-06 25.9 0.4 0.0035 17.4 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KFH42579.1 - 0.011 15.7 0.2 0.24 11.5 0.1 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 KFH42579.1 - 0.048 13.8 0.1 0.81 9.9 0.0 2.4 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PX PF00787.19 KFH42580.1 - 7.1e-19 67.6 0.5 7.1e-19 67.6 0.3 2.0 2 0 0 2 2 2 1 PX domain PRCC PF10253.4 KFH42580.1 - 0.29 11.8 8.4 0.43 11.2 2.2 2.3 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Sporozoite_P67 PF05642.6 KFH42580.1 - 1.8 6.3 12.0 2.6 5.7 8.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SelP_N PF04592.9 KFH42580.1 - 6.4 6.0 11.8 11 5.3 8.2 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region MmgE_PrpD PF03972.9 KFH42581.1 - 1.6e-97 326.5 0.4 1.8e-97 326.3 0.3 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Glyco_transf_15 PF01793.11 KFH42582.1 - 8.5e-133 442.3 1.6 1.1e-132 442.0 1.1 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase FAR1 PF03101.10 KFH42583.1 - 3.5e-05 24.2 0.1 6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.6 KFH42583.1 - 0.0035 17.5 0.0 0.0052 16.9 0.0 1.4 1 0 0 1 1 1 1 Transcription factor AFT Matrilin_ccoil PF10393.4 KFH42583.1 - 0.011 15.0 1.4 0.23 10.8 0.1 2.7 3 1 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Tropomyosin_1 PF12718.2 KFH42583.1 - 0.056 13.2 0.0 0.082 12.7 0.0 1.2 1 0 0 1 1 1 0 Tropomyosin like Sugarporin_N PF11471.3 KFH42583.1 - 0.077 12.6 0.8 0.077 12.6 0.5 2.7 2 1 1 3 3 3 0 Maltoporin periplasmic N-terminal extension DUF1664 PF07889.7 KFH42583.1 - 0.078 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ORF6C PF10552.4 KFH42583.1 - 0.16 11.6 0.1 8.5 6.1 0.1 2.3 1 1 1 2 2 2 0 ORF6C domain Ribosomal_L34e PF01199.13 KFH42585.1 - 4.5e-38 129.3 4.4 5.9e-38 128.9 3.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Zn_ribbon_recom PF13408.1 KFH42585.1 - 0.03 14.5 0.9 0.03 14.5 0.7 1.8 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain FhuF_C PF11575.3 KFH42585.1 - 2.1 8.0 6.8 2.5 7.8 0.2 2.6 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain COX5B PF01215.14 KFH42586.1 - 1e-36 125.6 0.0 1.3e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb CTNNB1_binding PF08347.6 KFH42586.1 - 0.032 14.4 0.0 0.047 13.9 0.0 1.3 1 0 0 1 1 1 0 N-terminal CTNNB1 binding Zn-ribbon_8 PF09723.5 KFH42586.1 - 0.05 13.5 0.4 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 Zinc ribbon domain DUF1462 PF07315.6 KFH42586.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) Phage_sheath_1 PF04984.9 KFH42586.1 - 0.17 10.2 0.0 0.24 9.8 0.0 1.1 1 0 0 1 1 1 0 Phage tail sheath protein zf-RING_5 PF14634.1 KFH42587.1 - 0.00021 20.9 4.7 0.00067 19.3 2.8 2.1 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KFH42587.1 - 0.017 14.8 0.3 0.056 13.1 0.2 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 KFH42587.1 - 0.017 15.1 0.7 0.017 15.1 0.5 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFH42587.1 - 0.065 13.1 0.6 0.065 13.1 0.4 2.6 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KFH42587.1 - 0.079 12.8 0.3 0.079 12.8 0.2 2.4 3 0 0 3 3 2 0 Ring finger domain Rtf2 PF04641.7 KFH42587.1 - 0.086 12.0 0.2 0.086 12.0 0.1 1.7 2 0 0 2 2 2 0 Rtf2 RING-finger zf-C3HC4 PF00097.20 KFH42587.1 - 0.14 11.8 4.6 0.49 10.1 3.1 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_4 PF13717.1 KFH42587.1 - 0.25 11.0 0.2 0.25 11.0 0.1 2.0 2 0 0 2 2 2 0 zinc-ribbon domain zf-C3HC4_3 PF13920.1 KFH42587.1 - 0.48 10.1 6.0 0.6 9.8 0.7 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 KFH42587.1 - 0.69 9.8 4.7 1.9 8.4 1.0 2.3 2 0 0 2 2 2 0 FYVE zinc finger zf-RING_4 PF14570.1 KFH42587.1 - 1 9.0 8.4 0.66 9.6 1.9 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zinc_ribbon_5 PF13719.1 KFH42587.1 - 2.1 8.0 4.6 0.31 10.6 0.1 2.0 2 0 0 2 2 2 0 zinc-ribbon domain Abhydrolase_6 PF12697.2 KFH42588.1 - 4.6e-23 82.2 1.9 1.1e-22 81.0 1.3 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH42588.1 - 4.4e-14 52.4 0.0 1.6e-13 50.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DSPc PF00782.15 KFH42588.1 - 9.5e-11 41.4 0.0 1.7e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Abhydrolase_1 PF00561.15 KFH42588.1 - 4.2e-09 36.2 0.0 5.3e-08 32.6 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold PTPlike_phytase PF14566.1 KFH42588.1 - 7.5e-06 26.0 0.0 1.8e-05 24.8 0.0 1.6 2 0 0 2 2 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 KFH42588.1 - 5.4e-05 22.6 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Thioesterase PF00975.15 KFH42588.1 - 0.0008 19.7 0.0 0.0018 18.5 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 KFH42588.1 - 0.0021 17.6 0.1 0.022 14.3 0.1 2.1 1 1 0 1 1 1 1 PGAP1-like protein VirJ PF06057.6 KFH42588.1 - 0.019 14.7 0.0 0.07 12.9 0.0 1.8 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) Lipase_3 PF01764.20 KFH42588.1 - 0.021 14.4 0.0 0.046 13.3 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF2305 PF10230.4 KFH42588.1 - 0.041 13.2 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) LCAT PF02450.10 KFH42588.1 - 0.092 11.7 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF3089 PF11288.3 KFH42588.1 - 0.1 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF900 PF05990.7 KFH42588.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Glyco_trans_4_4 PF13579.1 KFH42588.1 - 0.66 10.1 6.2 2 8.5 0.6 3.4 2 1 1 3 3 3 0 Glycosyl transferase 4-like domain WD40 PF00400.27 KFH42589.1 - 4.4e-27 92.9 9.6 1.5e-09 37.3 0.1 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KFH42589.1 - 3.2e-18 65.3 0.0 7e-18 64.3 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex OHCU_decarbox PF09349.5 KFH42590.1 - 8.4e-42 143.1 0.0 9.4e-42 142.9 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase DUF294 PF03445.8 KFH42590.1 - 0.049 13.2 0.0 0.1 12.2 0.0 1.6 1 1 1 2 2 2 0 Putative nucleotidyltransferase DUF294 MLANA PF14991.1 KFH42591.1 - 0.017 15.1 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein melan-A LRR19-TM PF15176.1 KFH42591.1 - 0.032 13.9 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Myc_target_1 PF15179.1 KFH42591.1 - 0.034 13.7 0.3 0.048 13.2 0.2 1.1 1 0 0 1 1 1 0 Myc target protein 1 Adeno_E3_CR2 PF02439.10 KFH42591.1 - 8.3 6.0 11.8 39 3.9 8.2 1.8 1 1 0 1 1 1 0 Adenovirus E3 region protein CR2 Lactonase PF10282.4 KFH42592.1 - 8.2e-57 192.8 0.0 1e-56 192.4 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.11 KFH42592.1 - 0.0064 14.8 0.0 0.51 8.5 0.0 2.2 1 1 1 2 2 2 2 Cytochrome D1 heme domain CHRD PF07452.7 KFH42592.1 - 0.078 13.6 0.7 0.45 11.1 0.0 2.5 3 0 0 3 3 3 0 CHRD domain PQQ_3 PF13570.1 KFH42592.1 - 0.18 12.1 2.2 24 5.3 0.1 3.9 3 1 1 4 4 4 0 PQQ-like domain Prp19 PF08606.6 KFH42593.1 - 2.5e-31 107.2 1.0 4.9e-31 106.2 0.7 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 KFH42593.1 - 4.6e-11 42.1 0.0 0.0082 16.0 0.0 4.4 5 0 0 5 5 5 3 WD domain, G-beta repeat zf-Nse PF11789.3 KFH42593.1 - 0.00047 19.6 0.0 0.0012 18.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit T2SS-T3SS_pil_N PF13629.1 KFH42593.1 - 0.062 12.8 0.1 0.21 11.1 0.1 1.9 1 0 0 1 1 1 0 Pilus formation protein N terminal region Glyco_hydro_18 PF00704.23 KFH42595.1 - 0.0038 16.7 0.0 0.0042 16.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_16 PF00722.16 KFH42597.1 - 2.2e-44 150.9 0.9 3e-44 150.5 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 KFH42597.1 - 0.53 10.3 15.9 0.13 12.2 7.8 2.1 2 0 0 2 2 2 0 Chitin recognition protein Git3 PF11710.3 KFH42598.1 - 1.3e-18 67.3 5.2 1.3e-18 67.3 3.6 2.0 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 KFH42598.1 - 2.5e-13 49.7 7.9 2.5e-13 49.7 5.4 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Git3_C PF11970.3 KFH42598.1 - 0.00022 20.9 1.3 0.001 18.8 0.1 2.7 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.6 KFH42598.1 - 0.00039 19.4 4.4 0.00039 19.4 3.1 1.6 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor ILVD_EDD PF00920.16 KFH42600.1 - 1e-194 647.8 1.2 1.2e-194 647.6 0.8 1.0 1 0 0 1 1 1 1 Dehydratase family WD40 PF00400.27 KFH42601.1 - 8.7e-32 107.8 5.5 1.1e-09 37.7 0.0 8.3 8 0 0 8 8 8 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 KFH42601.1 - 0.086 12.6 0.0 3.7 7.3 0.0 3.4 4 1 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Ribosomal_L18e PF00828.14 KFH42603.1 - 4.9e-19 68.9 0.5 8.8e-19 68.1 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 DUF4604 PF15377.1 KFH42604.1 - 1.9e-25 89.9 5.1 2.2e-25 89.6 3.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) DUF498 PF04430.9 KFH42605.1 - 3.3e-25 87.7 0.0 4.5e-25 87.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) EVC2_like PF12297.3 KFH42607.1 - 0.0026 16.4 0.0 0.0031 16.2 0.0 1.1 1 0 0 1 1 1 1 Ellis van Creveld protein 2 like protein PepSY_TM_3 PF13706.1 KFH42607.1 - 0.0077 15.6 2.8 0.015 14.6 2.0 1.5 1 0 0 1 1 1 1 PepSY-associated TM helix FixQ PF05545.6 KFH42607.1 - 0.014 15.0 1.1 0.031 13.9 0.7 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ PgaD PF13994.1 KFH42607.1 - 0.016 14.6 2.5 0.037 13.5 1.7 1.7 1 1 0 1 1 1 0 PgaD-like protein MtrF PF09472.5 KFH42607.1 - 0.02 14.0 0.2 0.031 13.5 0.1 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) BatA PF07584.6 KFH42607.1 - 0.024 14.8 1.2 0.044 13.9 0.9 1.4 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal UPF0104 PF03706.8 KFH42607.1 - 0.028 13.7 0.1 0.034 13.4 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) MFS_1 PF07690.11 KFH42607.1 - 0.04 12.6 0.0 0.053 12.2 0.0 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF4328 PF14219.1 KFH42607.1 - 0.043 13.1 1.8 0.091 12.0 0.2 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4328) Ctr PF04145.10 KFH42607.1 - 0.078 13.0 0.2 0.1 12.6 0.1 1.3 1 1 0 1 1 1 0 Ctr copper transporter family DUF347 PF03988.7 KFH42607.1 - 0.096 12.5 0.7 0.18 11.7 0.5 1.4 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Sensor PF13796.1 KFH42607.1 - 0.11 12.0 1.1 0.21 11.1 0.7 1.4 1 0 0 1 1 1 0 Putative sensor DUF2500 PF10694.4 KFH42607.1 - 0.15 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) TT_ORF1 PF02956.9 KFH42607.1 - 0.18 10.2 13.8 0.25 9.7 9.5 1.2 1 0 0 1 1 1 0 TT viral orf 1 PepSY_TM_2 PF13703.1 KFH42607.1 - 1.4 9.1 3.9 4.8 7.4 2.7 1.9 1 1 0 1 1 1 0 PepSY-associated TM helix DUF4501 PF14946.1 KFH42607.1 - 2.2 7.7 5.9 0.2 11.1 0.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4501) DUF1049 PF06305.6 KFH42607.1 - 5.8 6.4 10.9 10 5.6 6.7 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1049) Thioredoxin PF00085.15 KFH42608.1 - 4e-21 74.6 0.0 5e-21 74.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KFH42608.1 - 7e-05 22.9 0.0 0.00081 19.5 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 KFH42608.1 - 0.0032 17.0 0.0 0.0054 16.3 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KFH42608.1 - 0.026 14.6 0.0 0.19 11.8 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_7 PF13899.1 KFH42608.1 - 0.14 12.2 0.0 0.24 11.4 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like eRF1_1 PF03463.10 KFH42609.1 - 9.5e-30 102.8 0.0 1.7e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 KFH42609.1 - 2.4e-21 76.4 0.0 3.6e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 KFH42609.1 - 4.1e-17 62.4 0.0 7.5e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 3 Aldo_ket_red PF00248.16 KFH42610.1 - 2.8e-45 154.3 0.0 3.7e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family F-box-like PF12937.2 KFH42611.1 - 0.00062 19.4 0.0 0.0034 17.0 0.0 2.4 1 1 0 1 1 1 1 F-box-like ADH_zinc_N PF00107.21 KFH42612.1 - 6.3e-14 51.6 0.0 1.3e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFH42612.1 - 8.6e-09 35.1 0.2 7.9e-08 32.0 0.1 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KFH42612.1 - 0.065 14.1 0.0 0.16 12.8 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 KFH42613.1 - 3.9e-12 46.5 0.0 2.8e-11 43.7 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding 4HBT_3 PF13622.1 KFH42614.1 - 1.4e-46 159.3 0.1 1.9e-46 158.8 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 KFH42614.1 - 7.6e-06 25.5 0.0 0.00054 19.5 0.0 2.9 2 1 0 2 2 2 1 Acyl-CoA thioesterase FAM53 PF15242.1 KFH42614.1 - 0.32 10.5 3.2 0.61 9.5 2.2 1.4 1 1 0 1 1 1 0 Family of FAM53 NAD_binding_10 PF13460.1 KFH42615.1 - 9.3e-08 32.2 0.0 2.2e-07 31.0 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 KFH42615.1 - 0.0027 17.0 0.0 0.0044 16.2 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KFH42615.1 - 0.071 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Aldo_ket_red PF00248.16 KFH42616.1 - 4.3e-72 242.3 0.0 4.8e-72 242.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AAA PF00004.24 KFH42618.1 - 7.5e-19 68.2 0.0 1.4e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFH42618.1 - 0.0015 18.6 0.1 0.0099 16.0 0.0 2.2 1 1 1 2 2 2 1 AAA domain Zot PF05707.7 KFH42618.1 - 0.0068 15.8 0.1 0.16 11.3 0.1 2.4 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_16 PF13191.1 KFH42618.1 - 0.0074 16.2 0.0 0.025 14.5 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 KFH42618.1 - 0.014 15.2 0.1 0.061 13.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KFH42618.1 - 0.018 15.8 0.0 0.17 12.7 0.0 2.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KFH42618.1 - 0.09 13.0 0.5 0.4 10.9 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 KFH42618.1 - 0.11 12.2 0.2 0.24 11.1 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain NB-ARC PF00931.17 KFH42618.1 - 0.16 10.7 0.1 0.35 9.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain MUG113 PF13455.1 KFH42621.1 - 1.6e-30 105.3 0.1 3.2e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 KFH42621.1 - 2.6e-21 75.8 0.0 5.5e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 T5orf172 domain Sugar_tr PF00083.19 KFH42623.1 - 9.4e-108 360.6 18.2 1.1e-107 360.4 12.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH42623.1 - 2.3e-33 115.3 27.7 3.2e-32 111.6 14.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFH42623.1 - 0.0024 16.1 0.7 0.0036 15.5 0.1 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) FA_desaturase PF00487.19 KFH42624.1 - 3.9e-38 131.3 24.6 5.5e-38 130.8 17.0 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KFH42624.1 - 1.9e-09 37.1 0.0 3.5e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Actin PF00022.14 KFH42625.1 - 1.6e-97 326.4 0.0 2e-97 326.1 0.0 1.0 1 0 0 1 1 1 1 Actin Cerato-platanin PF07249.7 KFH42628.1 - 6.5e-06 26.1 0.2 1.1e-05 25.4 0.2 1.4 1 0 0 1 1 1 1 Cerato-platanin Ferritin_2 PF13668.1 KFH42631.1 - 9.9e-15 54.6 0.0 1.5e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Glyco_hydro_16 PF00722.16 KFH42632.1 - 3.9e-21 75.1 0.1 6.5e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 KFH42632.1 - 2.8e-08 32.3 0.0 0.0029 15.8 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) ILVD_EDD PF00920.16 KFH42633.1 - 3.8e-210 698.7 0.1 4.5e-210 698.5 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family ArsB PF02040.10 KFH42636.1 - 5.5e-11 42.0 6.4 9.4e-10 38.0 2.9 2.4 2 0 0 2 2 2 2 Arsenical pump membrane protein DUF4634 PF15465.1 KFH42636.1 - 0.15 12.2 0.0 1.2 9.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4634) DUF89 PF01937.14 KFH42637.1 - 6.5e-130 433.0 0.1 7.5e-130 432.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Acyltransferase PF01553.16 KFH42638.1 - 6e-07 28.9 0.0 1.1e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase COesterase PF00135.23 KFH42639.1 - 6.6e-91 305.6 0.0 7.2e-83 279.1 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 KFH42639.1 - 1.8e-12 47.3 0.4 1.1e-11 44.7 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFH42639.1 - 0.014 15.1 0.0 0.066 12.9 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFH42639.1 - 0.23 10.6 1.1 0.33 10.1 0.1 1.8 2 1 0 2 2 2 0 Prolyl oligopeptidase family Exo_endo_phos PF03372.18 KFH42640.1 - 5.4e-17 62.5 2.5 7.6e-17 62.0 1.8 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KFH42640.1 - 0.00065 19.2 0.1 0.0042 16.6 0.0 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase He_PIG PF05345.7 KFH42640.1 - 0.0013 18.7 3.2 0.0034 17.3 2.2 1.8 1 0 0 1 1 1 1 Putative Ig domain Peptidase_C25_C PF03785.9 KFH42640.1 - 0.089 12.6 1.0 0.18 11.6 0.7 1.4 1 0 0 1 1 1 0 Peptidase family C25, C terminal ig-like domain Big_2 PF02368.13 KFH42640.1 - 0.21 11.4 7.0 0.42 10.5 3.5 2.2 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) RAI16-like PF10257.4 KFH42641.1 - 2.9e-78 263.2 0.8 5.2e-78 262.4 0.6 1.4 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein DUF2890 PF11081.3 KFH42641.1 - 9.3 6.2 21.6 1.6 8.7 5.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) TBPIP PF07106.8 KFH42643.1 - 2.8 7.4 21.0 1.8 8.0 2.8 3.2 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Bac_GDH PF05088.7 KFH42643.1 - 5.6 4.2 15.0 7.2 3.8 10.4 1.1 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase Abhydrolase_6 PF12697.2 KFH42645.1 - 2e-06 27.8 0.5 4.7e-06 26.6 0.3 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH42645.1 - 2.5e-05 24.0 0.3 0.00029 20.6 0.2 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KFH42645.1 - 8.8e-05 22.1 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 KFH42645.1 - 0.04 13.1 0.0 0.067 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF2305 PF10230.4 KFH42645.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Kinesin PF00225.18 KFH42646.1 - 3.7e-106 354.6 1.5 3.7e-106 354.6 1.1 2.1 2 1 0 2 2 2 1 Kinesin motor domain WEMBL PF05701.6 KFH42646.1 - 3.1e-05 22.6 44.3 0.00071 18.1 30.9 2.4 1 1 0 1 1 1 1 Weak chloroplast movement under blue light Reo_sigmaC PF04582.7 KFH42646.1 - 0.012 14.7 12.3 0.096 11.8 3.4 3.0 1 1 2 3 3 3 0 Reovirus sigma C capsid protein LPP PF04728.8 KFH42646.1 - 0.99 9.2 6.9 0.18 11.6 0.4 3.1 4 0 0 4 4 4 0 Lipoprotein leucine-zipper bZIP_1 PF00170.16 KFH42646.1 - 1.6 8.7 35.2 1.3 9.0 1.1 6.4 3 1 2 5 5 5 0 bZIP transcription factor EcKinase PF02958.15 KFH42647.1 - 1.3e-15 57.3 0.0 2.4e-15 56.4 0.0 1.3 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.18 KFH42647.1 - 4.4e-09 36.4 2.0 5.8e-09 36.0 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFH42647.1 - 0.037 13.6 0.0 0.28 10.7 0.0 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase Na_Ca_ex PF01699.19 KFH42648.1 - 2.3e-23 82.3 25.7 7.7e-16 57.9 3.9 3.2 3 2 1 4 4 4 2 Sodium/calcium exchanger protein DUF872 PF05915.7 KFH42648.1 - 0.2 11.5 4.1 6.8 6.5 0.1 3.0 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) Mannosyl_trans3 PF11051.3 KFH42649.1 - 4.9e-41 140.8 0.0 1.1e-40 139.7 0.0 1.6 2 0 0 2 2 2 1 Mannosyltransferase putative Glyco_hydro_61 PF03443.9 KFH42650.1 - 1.4e-68 231.0 0.3 1.6e-68 230.8 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DNA_pol_A_exo1 PF01612.15 KFH42651.1 - 0.05 13.0 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 3'-5' exonuclease Sod_Fe_C PF02777.13 KFH42652.1 - 1.2e-33 115.1 0.5 2.3e-33 114.2 0.1 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KFH42652.1 - 1.3e-33 115.0 8.9 2.5e-33 114.1 0.9 2.9 3 0 0 3 3 3 2 Iron/manganese superoxide dismutases, alpha-hairpin domain QueF_N PF14819.1 KFH42652.1 - 0.26 11.4 1.1 4.2 7.4 0.0 2.2 2 0 0 2 2 2 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term LIM PF00412.17 KFH42654.1 - 1.6e-23 82.5 25.6 3.2e-08 33.5 1.7 3.7 4 0 0 4 4 4 3 LIM domain DUF2321 PF10083.4 KFH42654.1 - 0.35 10.3 4.8 0.099 12.1 0.3 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Nudix_N_2 PF14803.1 KFH42654.1 - 1.2 8.9 16.0 3 7.6 0.6 5.5 5 0 0 5 5 5 0 Nudix N-terminal Nup84_Nup100 PF04121.8 KFH42655.1 - 1.4e-63 214.7 0.0 2.7e-63 213.7 0.0 1.5 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 Rep_4 PF05797.6 KFH42655.1 - 0.12 11.0 0.1 0.2 10.3 0.0 1.3 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) Mad3_BUB1_I PF08311.7 KFH42656.1 - 1.6e-43 147.4 0.2 3.4e-43 146.4 0.1 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 KFH42656.1 - 1.4e-12 47.2 0.0 2.6e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH42656.1 - 0.0011 18.1 0.0 0.0044 16.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase PI3K_1B_p101 PF10486.4 KFH42656.1 - 0.41 8.1 2.3 0.62 7.5 1.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Fungal_trans PF04082.13 KFH42657.1 - 1.7e-16 59.8 0.2 2.8e-16 59.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH42657.1 - 1.3e-07 31.4 11.1 2.1e-07 30.7 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.7 KFH42657.1 - 0.18 11.3 0.0 0.41 10.2 0.0 1.5 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Dynamin_M PF01031.15 KFH42659.1 - 3.3e-114 380.6 0.0 6.7e-114 379.6 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 KFH42659.1 - 1.4e-56 190.9 0.0 3.3e-56 189.7 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KFH42659.1 - 6.9e-30 102.8 2.1 6.9e-30 102.8 1.4 2.2 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KFH42659.1 - 0.0032 17.3 0.0 0.012 15.5 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFH42659.1 - 0.016 15.6 0.0 0.045 14.2 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein Ank_2 PF12796.2 KFH42661.1 - 1e-38 131.5 0.1 1.1e-12 48.0 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFH42661.1 - 1.2e-36 122.6 0.0 8.8e-06 25.2 0.0 6.4 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 KFH42661.1 - 2e-34 116.8 0.6 2.3e-10 40.3 0.0 4.4 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFH42661.1 - 5.8e-31 103.4 0.0 6.4e-05 22.8 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 KFH42661.1 - 1.8e-29 101.5 1.6 1.8e-10 41.0 0.0 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) SH3_9 PF14604.1 KFH42662.1 - 7.7e-26 89.4 3.1 5.5e-12 45.0 0.1 3.2 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.23 KFH42662.1 - 2.8e-21 74.6 5.0 3.6e-12 45.4 0.2 3.5 3 0 0 3 3 3 2 SH3 domain SH3_2 PF07653.12 KFH42662.1 - 1.3e-16 59.7 0.1 8.4e-09 34.7 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.15 KFH42662.1 - 5.8e-14 52.0 0.0 9.7e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein AOX PF01786.12 KFH42664.1 - 8.2e-87 289.9 0.0 9.9e-87 289.6 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase MDM31_MDM32 PF08118.6 KFH42665.1 - 9e-186 618.2 0.7 1.2e-185 617.7 0.5 1.1 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins SMN PF06003.7 KFH42665.1 - 0.06 12.4 0.9 0.11 11.6 0.6 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) 4HBT PF03061.17 KFH42666.1 - 1.9e-11 43.8 0.0 3.8e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily AP_endonuc_2 PF01261.19 KFH42667.1 - 3e-27 95.3 0.4 4.9e-27 94.6 0.3 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel V-ATPase_C PF03223.10 KFH42668.1 - 1.2e-111 373.1 0.0 1.4e-111 373.0 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C mRNA_cap_C PF03919.10 KFH42668.1 - 0.0022 18.2 0.5 0.02 15.1 0.0 2.3 2 0 0 2 2 2 1 mRNA capping enzyme, C-terminal domain Prefoldin PF02996.12 KFH42669.1 - 2.1e-27 95.1 1.1 3e-27 94.6 0.8 1.2 1 0 0 1 1 1 1 Prefoldin subunit Sec2p PF06428.6 KFH42669.1 - 0.001 18.8 5.1 0.16 11.8 0.1 2.3 2 0 0 2 2 2 2 GDP/GTP exchange factor Sec2p Prefoldin_2 PF01920.15 KFH42669.1 - 0.0014 18.3 5.5 0.069 12.9 0.5 2.1 2 0 0 2 2 2 2 Prefoldin subunit Fib_alpha PF08702.5 KFH42669.1 - 0.011 15.8 3.3 0.55 10.3 0.3 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TnpV PF14198.1 KFH42669.1 - 0.022 14.6 2.2 0.084 12.7 0.1 2.1 2 0 0 2 2 2 0 Transposon-encoded protein TnpV Syntaxin-6_N PF09177.6 KFH42669.1 - 0.07 13.5 2.4 2 8.8 0.2 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal NAAA-beta PF15508.1 KFH42669.1 - 0.073 13.4 0.2 0.96 9.8 0.0 2.1 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Cep57_MT_bd PF06657.8 KFH42669.1 - 0.085 12.8 0.6 0.085 12.8 0.4 1.8 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 FliG_M PF14841.1 KFH42669.1 - 0.12 12.3 1.8 13 5.9 0.1 2.3 2 0 0 2 2 2 0 FliG middle domain Rootletin PF15035.1 KFH42669.1 - 0.14 12.1 6.4 0.13 12.2 0.3 2.1 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion HSCB_C PF07743.8 KFH42669.1 - 0.18 12.2 2.9 0.25 11.8 0.2 2.1 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain TACC PF05010.9 KFH42669.1 - 0.27 10.9 4.3 2.2 7.9 0.1 2.0 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) Spc7 PF08317.6 KFH42669.1 - 0.41 9.2 5.1 1.5 7.3 3.5 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.4 KFH42669.1 - 0.43 10.4 6.2 3.1 7.6 0.5 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KxDL PF10241.4 KFH42669.1 - 0.46 10.4 4.4 8.6 6.3 0.2 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein CENP-Q PF13094.1 KFH42669.1 - 1.9 8.5 7.6 0.8 9.7 0.6 2.2 1 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit COG2 PF06148.6 KFH42669.1 - 2.4 8.0 5.8 2.7 7.8 0.2 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 SPX PF03105.14 KFH42669.1 - 8.4 6.0 6.7 4 7.1 1.4 1.9 1 1 1 2 2 2 0 SPX domain CBF PF03914.12 KFH42670.1 - 3.7e-46 156.5 0.7 1.1e-45 155.0 0.0 2.2 2 0 0 2 2 2 1 CBF/Mak21 family Rad60-SLD PF11976.3 KFH42671.1 - 1.6e-20 72.5 0.1 1.9e-20 72.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KFH42671.1 - 5.4e-08 32.1 0.1 6.5e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family AAA PF00004.24 KFH42672.1 - 1.4e-15 57.6 0.0 2.4e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFH42672.1 - 5.6e-11 42.7 0.0 1.2e-09 38.4 0.0 2.6 1 1 0 1 1 1 1 AAA ATPase domain BAH PF01426.13 KFH42672.1 - 5.3e-07 29.4 0.0 1.2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 BAH domain AAA_22 PF13401.1 KFH42672.1 - 1.1e-06 28.7 0.0 2.6e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFH42672.1 - 0.0004 20.0 0.1 0.0012 18.5 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 KFH42672.1 - 0.0036 16.9 0.0 0.0065 16.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_17 PF13207.1 KFH42672.1 - 0.0071 17.1 0.0 0.038 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KFH42672.1 - 0.0078 15.9 0.0 0.065 12.9 0.0 2.1 1 1 0 1 1 1 1 Archaeal ATPase AAA_18 PF13238.1 KFH42672.1 - 0.013 15.8 0.0 0.034 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 KFH42672.1 - 0.014 14.4 0.0 0.025 13.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 KFH42672.1 - 0.028 14.0 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zot PF05707.7 KFH42672.1 - 0.03 13.7 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_10 PF12846.2 KFH42672.1 - 0.045 13.1 0.1 1.4 8.2 0.0 2.3 1 1 1 2 2 2 0 AAA-like domain AAA_32 PF13654.1 KFH42672.1 - 0.26 9.8 0.0 0.42 9.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Mod_r PF07200.8 KFH42673.1 - 6.8e-06 26.0 5.2 6.8e-06 26.0 3.6 3.1 2 1 1 3 3 3 2 Modifier of rudimentary (Mod(r)) protein BAF1_ABF1 PF04684.8 KFH42673.1 - 0.14 10.9 9.2 0.18 10.6 6.4 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TFIIA PF03153.8 KFH42673.1 - 2.2 8.0 16.9 3.2 7.5 11.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FCP1_C PF09309.5 KFH42673.1 - 3.8 6.7 10.5 0.58 9.4 3.7 1.9 2 0 0 2 2 2 0 FCP1, C-terminal PHD_3 PF13922.1 KFH42673.1 - 5.4 7.3 7.2 16 5.7 5.0 1.8 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx F-box PF00646.28 KFH42674.1 - 1.2e-05 24.8 0.0 2.9e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KFH42674.1 - 0.00015 21.3 0.1 0.00015 21.3 0.1 1.8 2 0 0 2 2 2 1 F-box-like CHCH PF06747.8 KFH42676.1 - 8.6e-05 22.3 1.5 0.00018 21.2 1.1 1.6 1 1 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 KFH42676.1 - 0.041 13.9 2.8 0.42 10.6 2.2 1.9 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.8 KFH42676.1 - 0.22 11.5 3.6 2.6 8.1 0.3 2.3 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 KFH42676.1 - 0.33 10.7 2.9 0.8 9.5 2.0 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.7 KFH42676.1 - 0.49 10.2 2.1 7.1 6.5 1.5 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) TMF_TATA_bd PF12325.3 KFH42677.1 - 1.4e-39 134.5 7.9 1.4e-39 134.5 5.5 6.1 3 2 1 5 5 5 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 KFH42677.1 - 4.2e-18 64.9 11.2 4.2e-18 64.9 7.8 9.2 5 3 4 10 10 10 1 TATA element modulatory factor 1 DNA binding DUF4618 PF15397.1 KFH42677.1 - 0.0012 18.2 10.2 0.0012 18.2 7.1 5.6 4 2 1 5 5 5 1 Domain of unknown function (DUF4618) Rootletin PF15035.1 KFH42677.1 - 0.021 14.8 0.9 0.021 14.8 0.6 5.7 2 1 1 4 4 4 0 Ciliary rootlet component, centrosome cohesion NPV_P10 PF05531.7 KFH42677.1 - 0.49 10.6 23.9 2.8 8.2 0.2 6.6 5 1 0 5 5 5 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.6 KFH42677.1 - 0.69 9.8 37.7 0.23 11.3 1.7 8.2 8 0 0 8 8 8 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.7 KFH42677.1 - 0.97 9.2 27.4 8.8 6.1 0.0 6.9 4 1 4 8 8 8 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 KFH42677.1 - 2.3 7.2 30.7 0.24 10.5 1.8 4.9 2 1 3 5 5 5 0 Reovirus sigma C capsid protein GAS PF13851.1 KFH42677.1 - 4.1 6.5 87.7 0.012 14.7 14.7 5.3 3 1 2 5 5 5 0 Growth-arrest specific micro-tubule binding WD40 PF00400.27 KFH42678.1 - 1e-53 177.3 14.1 3.4e-09 36.2 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KFH42678.1 - 0.00051 18.3 4.0 3.4 5.6 0.0 4.3 1 1 4 5 5 5 4 Nucleoporin Nup120/160 Glutaredoxin PF00462.19 KFH42679.1 - 3.1e-17 62.2 0.0 1.5e-16 60.0 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 KFH42679.1 - 3.8e-14 52.2 0.0 8e-14 51.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KFH42679.1 - 0.016 15.3 0.0 0.96 9.6 0.0 2.4 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_3 PF13192.1 KFH42679.1 - 0.11 12.2 0.0 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin domain ArsC PF03960.10 KFH42679.1 - 0.11 12.5 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 ArsC family F-box PF00646.28 KFH42680.1 - 1.3e-08 34.2 0.4 3.3e-08 32.9 0.3 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KFH42680.1 - 4.3e-06 26.3 0.2 4.3e-06 26.3 0.2 2.1 2 0 0 2 2 2 1 F-box-like KH_1 PF00013.24 KFH42681.1 - 3.6e-05 23.3 0.9 6.9e-05 22.4 0.4 1.6 2 0 0 2 2 2 1 KH domain APS_kinase PF01583.15 KFH42682.1 - 1.8e-71 238.9 0.0 2.3e-71 238.5 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 KFH42682.1 - 5.4e-07 29.5 0.0 9.8e-07 28.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFH42682.1 - 1.8e-06 28.7 0.0 2.9e-06 28.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFH42682.1 - 1.2e-05 25.5 0.0 2.3e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 KFH42682.1 - 0.00012 21.3 0.0 0.00023 20.4 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 KFH42682.1 - 0.0073 15.4 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin PRK PF00485.13 KFH42682.1 - 0.018 14.6 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family 6PF2K PF01591.13 KFH42682.1 - 0.025 13.6 0.0 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_29 PF13555.1 KFH42682.1 - 0.026 14.0 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain CPT PF07931.7 KFH42682.1 - 0.028 14.0 0.2 0.11 12.0 0.1 2.1 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.1 KFH42682.1 - 0.031 14.2 0.3 0.071 13.0 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_26 PF13500.1 KFH42682.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Dicty_REP PF05086.7 KFH42683.1 - 0.75 7.4 3.9 1.3 6.7 2.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 KFH42683.1 - 5.5 6.7 12.5 0.31 10.7 3.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) eIF3_subunit PF08597.5 KFH42684.1 - 2.7e-71 239.9 15.9 3.1e-71 239.8 11.0 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit FNIP_N PF14636.1 KFH42684.1 - 0.95 9.9 5.3 0.65 10.4 0.8 2.2 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus PRP4 PF08799.6 KFH42684.1 - 1.2 8.5 5.6 2.5 7.4 3.9 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like NAM-associated PF14303.1 KFH42684.1 - 4.7 7.5 18.8 0.62 10.3 7.5 2.1 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain tRNA-synt_2b PF00587.20 KFH42685.1 - 6.6e-35 120.2 0.0 9.7e-35 119.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KFH42685.1 - 2.2e-13 49.9 0.0 4.4e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain zf-H2C2_2 PF13465.1 KFH42686.1 - 2.2e-14 52.9 8.5 4.9e-08 32.8 0.2 3.8 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KFH42686.1 - 9.4e-13 47.6 12.2 7.6e-06 25.9 1.6 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFH42686.1 - 4.7e-11 42.2 12.3 3.6e-05 23.7 1.8 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFH42686.1 - 5.2e-08 32.7 1.6 0.028 14.5 0.1 3.9 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFH42686.1 - 0.0019 18.3 8.3 0.013 15.6 0.2 3.7 5 0 0 5 5 5 2 Zinc-finger of C2H2 type Zn_ribbon_recom PF13408.1 KFH42686.1 - 0.18 12.0 0.7 0.53 10.5 0.5 1.8 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain LIM PF00412.17 KFH42686.1 - 0.71 9.9 3.9 6.2 6.9 2.7 2.2 1 1 1 2 2 2 0 LIM domain zf-C2H2_6 PF13912.1 KFH42686.1 - 1.6 8.7 10.2 10 6.1 0.4 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-PARP PF00645.13 KFH42689.1 - 1.7e-20 73.0 0.1 3.5e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region 4HBT_3 PF13622.1 KFH42690.1 - 3.5e-43 148.1 8.9 7e-43 147.2 6.1 1.5 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 KFH42690.1 - 4e-24 84.7 0.0 4.1e-10 39.4 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase Pyridox_oxidase PF01243.15 KFH42691.1 - 2.9e-11 43.2 0.0 5.7e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 KFH42691.1 - 0.011 15.6 0.1 0.052 13.3 0.0 1.9 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase Pirin PF02678.11 KFH42692.1 - 4.8e-24 84.2 0.7 1.4e-22 79.5 0.5 2.3 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.6 KFH42692.1 - 0.0063 15.9 1.9 0.56 9.7 0.2 3.1 2 1 0 2 2 2 2 Cupin domain Pkinase PF00069.20 KFH42693.1 - 1.2e-49 168.7 0.0 1.3e-46 158.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFH42693.1 - 1.2e-32 113.0 0.0 6.1e-32 110.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH42693.1 - 0.00013 21.0 0.0 0.0002 20.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KFH42693.1 - 0.00036 19.4 0.1 0.00073 18.4 0.1 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 KFH42693.1 - 0.053 12.3 0.0 0.081 11.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 KFH42693.1 - 0.13 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family MoaE PF02391.12 KFH42694.1 - 7.1e-32 109.6 0.0 9e-32 109.3 0.0 1.1 1 0 0 1 1 1 1 MoaE protein BPL_LplA_LipB PF03099.14 KFH42695.1 - 5.3e-07 29.6 0.0 9.3e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Asp PF00026.18 KFH42696.1 - 7.6e-61 206.0 0.2 9.3e-61 205.8 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFH42696.1 - 1.8e-07 31.2 0.0 3.4e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal RVP PF00077.15 KFH42696.1 - 0.00065 19.5 0.2 0.087 12.7 0.0 2.8 2 1 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KFH42696.1 - 0.0014 19.0 0.8 1.8 9.1 0.0 3.7 4 0 0 4 4 4 1 Aspartyl protease gag-asp_proteas PF13975.1 KFH42696.1 - 0.046 13.5 0.1 8.5 6.2 0.0 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease TAXi_C PF14541.1 KFH42696.1 - 0.058 12.9 0.0 0.18 11.3 0.0 1.8 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal DUF3433 PF11915.3 KFH42697.1 - 3.8e-24 84.6 17.0 1.5e-21 76.3 0.3 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) DUF4381 PF14316.1 KFH42697.1 - 0.068 13.2 2.8 3 7.9 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) CPSase_L_D2 PF02786.12 KFH42699.1 - 4.7e-72 241.6 0.0 8.2e-72 240.8 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 KFH42699.1 - 1.8e-35 121.1 0.0 3.8e-35 120.1 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 KFH42699.1 - 2.4e-33 114.5 0.0 5e-33 113.4 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 KFH42699.1 - 1.3e-17 64.1 0.1 2.6e-16 59.8 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KFH42699.1 - 2.6e-17 62.1 1.3 8.5e-17 60.5 0.9 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 KFH42699.1 - 2.8e-17 62.4 0.0 4.8e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 KFH42699.1 - 6.3e-11 41.7 0.0 9.2e-05 22.0 0.0 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 KFH42699.1 - 1.3e-07 31.2 0.0 4.3e-07 29.5 0.0 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KFH42699.1 - 1.7e-07 30.7 0.0 4e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 KFH42699.1 - 8.3e-06 26.1 0.2 0.32 11.3 0.0 3.7 3 1 0 3 3 3 2 HlyD family secretion protein HlyD PF00529.15 KFH42699.1 - 3.2e-05 23.3 0.0 0.22 10.7 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.9 KFH42699.1 - 3.8e-05 23.5 0.0 9.5e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_2 PF12700.2 KFH42699.1 - 0.0051 16.0 0.1 1.8 7.6 0.0 2.3 1 1 1 2 2 2 2 HlyD family secretion protein CoA_binding_2 PF13380.1 KFH42699.1 - 0.0066 16.6 0.2 6.2 7.0 0.1 3.7 3 2 0 3 3 2 1 CoA binding domain GCV_H PF01597.14 KFH42699.1 - 0.08 12.6 0.2 0.29 10.8 0.1 2.0 1 0 0 1 1 1 0 Glycine cleavage H-protein HTH_13 PF11972.3 KFH42700.1 - 0.17 11.7 1.3 0.33 10.8 0.3 1.8 2 0 0 2 2 2 0 HTH DNA binding domain p450 PF00067.17 KFH42702.1 - 1.9e-71 240.9 0.0 2.3e-71 240.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PI3_PI4_kinase PF00454.22 KFH42704.1 - 1.2e-46 159.1 0.0 2e-46 158.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 KFH42704.1 - 4.8e-36 124.4 5.1 8.8e-36 123.6 3.5 1.5 1 0 0 1 1 1 1 FAT domain UME PF08064.8 KFH42704.1 - 3.4e-27 94.5 0.0 3e-24 85.0 0.0 3.2 3 0 0 3 3 3 2 UME (NUC010) domain FATC PF02260.15 KFH42704.1 - 6.5e-16 57.4 0.0 1.6e-15 56.1 0.0 1.7 1 0 0 1 1 1 1 FATC domain TPR_19 PF14559.1 KFH42704.1 - 0.034 14.4 6.2 0.49 10.7 0.1 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat GDI PF00996.13 KFH42705.1 - 5e-35 120.6 0.0 9.5e-35 119.7 0.0 1.3 1 1 0 1 1 1 1 GDP dissociation inhibitor Rad21_Rec8_N PF04825.8 KFH42706.1 - 9.5e-31 106.0 0.0 1.5e-30 105.3 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein DUF3248 PF11609.3 KFH42707.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3248) Fungal_trans PF04082.13 KFH42708.1 - 2.5e-11 42.9 0.1 4.6e-11 42.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH42708.1 - 0.0085 15.9 5.7 0.018 14.9 3.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSP70 PF00012.15 KFH42709.1 - 5.7e-10 37.7 0.0 3.4e-09 35.1 0.0 1.8 2 0 0 2 2 2 2 Hsp70 protein AIG2 PF06094.7 KFH42710.1 - 4.3e-09 36.7 0.1 8.2e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family AIG2_2 PF13772.1 KFH42710.1 - 0.00012 22.1 0.9 0.0042 17.1 0.0 2.5 3 0 0 3 3 3 1 AIG2-like family Oxysterol_BP PF01237.13 KFH42711.1 - 1.4e-127 425.0 0.0 1.1e-126 422.1 0.0 2.1 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.2 KFH42711.1 - 8.5e-20 70.8 0.0 2e-13 50.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFH42711.1 - 2.1e-17 61.9 0.2 5e-07 29.2 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KFH42711.1 - 8.5e-17 61.1 0.2 2.1e-08 34.4 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFH42711.1 - 2.1e-15 55.2 1.0 7.2e-06 25.7 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KFH42711.1 - 7.8e-15 54.5 0.3 4.3e-08 33.1 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) PH PF00169.24 KFH42711.1 - 9.4e-13 48.2 0.7 1.9e-12 47.3 0.5 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 KFH42711.1 - 1e-07 31.9 0.8 2.2e-07 30.8 0.5 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain CMAS PF02353.15 KFH42712.1 - 4e-56 190.0 0.1 5e-56 189.7 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KFH42712.1 - 9.4e-12 44.9 0.0 1.6e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH42712.1 - 9.2e-07 29.4 0.0 2.9e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH42712.1 - 2.2e-06 28.0 0.0 4.3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH42712.1 - 2e-05 24.2 0.0 3.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 KFH42712.1 - 3.9e-05 23.0 0.0 6.3e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 KFH42712.1 - 6e-05 23.0 0.0 0.00065 19.7 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFH42712.1 - 0.00014 21.3 0.0 0.00022 20.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KFH42712.1 - 0.00031 21.0 0.0 0.00068 19.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH42712.1 - 0.0016 18.9 0.0 0.0027 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KFH42712.1 - 0.021 14.3 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FokI_C PF02980.11 KFH42712.1 - 0.025 14.2 0.0 0.46 10.1 0.0 2.2 2 0 0 2 2 2 0 Restriction endonuclease FokI, catalytic domain PrmA PF06325.8 KFH42712.1 - 0.099 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Mem_trans PF03547.13 KFH42713.1 - 1e-53 182.0 0.0 1.3e-53 181.6 0.0 1.1 1 0 0 1 1 1 1 Membrane transport protein G-patch PF01585.18 KFH42714.1 - 4.7e-11 42.2 2.0 1.1e-10 41.1 1.4 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KFH42714.1 - 4.8e-06 26.3 1.7 1.6e-05 24.6 1.2 1.9 1 0 0 1 1 1 1 DExH-box splicing factor binding site zf-RanBP PF00641.13 KFH42714.1 - 7.6e-06 24.9 3.1 1.8e-05 23.7 2.2 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_6 PF14259.1 KFH42714.1 - 0.0001 22.1 0.0 0.45 10.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFH42714.1 - 0.00016 21.1 0.0 0.065 12.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RED_N PF07808.8 KFH42714.1 - 0.009 15.2 1.9 0.023 13.9 1.3 1.7 1 0 0 1 1 1 1 RED-like protein N-terminal region zf-C2H2_2 PF12756.2 KFH42714.1 - 0.029 14.4 0.4 0.094 12.8 0.0 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) SUR7 PF06687.7 KFH42715.1 - 3.5e-29 101.8 4.2 4.2e-29 101.6 2.9 1.0 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 KFH42715.1 - 0.0012 18.6 8.6 0.0046 16.6 3.6 2.2 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Fig1 PF12351.3 KFH42715.1 - 0.75 9.6 7.1 0.047 13.5 1.7 1.4 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 ALO PF04030.9 KFH42718.1 - 7.4e-81 271.5 0.0 1e-80 271.1 0.0 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 KFH42718.1 - 8.4e-29 99.8 0.1 1.2e-28 99.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Ferric_reduct PF01794.14 KFH42719.1 - 7.4e-19 68.0 3.8 7.4e-19 68.0 2.6 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KFH42719.1 - 9.5e-15 54.3 0.1 2.8e-14 52.8 0.0 1.9 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.7 KFH42719.1 - 2.1e-13 50.4 0.0 5.9e-12 45.7 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 KFH42719.1 - 0.00036 21.0 0.0 0.041 14.4 0.0 2.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain TRI5 PF06330.6 KFH42720.1 - 6.2e-21 74.4 0.0 8.9e-21 73.9 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) SSF PF00474.12 KFH42721.1 - 2.2e-21 75.9 27.7 2.2e-21 75.9 19.2 1.7 2 0 0 2 2 2 1 Sodium:solute symporter family RNase_PH PF01138.16 KFH42722.1 - 2.5e-19 69.8 0.0 7e-19 68.4 0.0 1.8 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KFH42722.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Nucleoplasmin PF03066.10 KFH42722.1 - 0.063 12.7 0.2 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 Nucleoplasmin Rad21_Rec8 PF04824.11 KFH42723.1 - 3.2e-06 26.2 0.0 6.1e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 KFH42723.1 - 0.013 15.1 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 ScpA/B protein DUF2328 PF10090.4 KFH42723.1 - 0.084 12.0 0.1 0.18 10.9 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2328) Amidoligase_2 PF12224.3 KFH42724.1 - 8.6e-21 74.6 0.0 3.3e-20 72.7 0.0 1.7 2 0 0 2 2 2 1 Putative amidoligase enzyme Aminotran_1_2 PF00155.16 KFH42725.1 - 3.1e-47 161.2 0.0 3.7e-47 161.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KFH42725.1 - 0.0073 15.4 0.0 0.019 14.1 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 KFH42725.1 - 0.009 14.3 0.0 0.016 13.5 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme E2R135 PF11570.3 KFH42726.1 - 0.031 14.3 7.9 0.055 13.5 5.5 1.4 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 Atg14 PF10186.4 KFH42726.1 - 0.094 11.6 13.4 0.21 10.4 9.3 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TPR_MLP1_2 PF07926.7 KFH42726.1 - 0.4 10.4 21.1 0.83 9.4 14.6 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein RTBV_P46 PF06216.6 KFH42726.1 - 0.49 9.1 2.1 0.76 8.5 1.4 1.2 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein DUF812 PF05667.6 KFH42726.1 - 0.54 8.7 14.4 1 7.8 10.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) V_ATPase_I PF01496.14 KFH42726.1 - 1.5 6.5 8.7 2.6 5.7 6.0 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.6 KFH42726.1 - 1.9 7.0 17.7 0.9 8.1 10.8 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF3450 PF11932.3 KFH42726.1 - 2.2 7.4 16.4 4 6.6 11.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF342 PF03961.8 KFH42726.1 - 2.8 6.2 7.2 3.8 5.8 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF972 PF06156.8 KFH42726.1 - 8.4 6.7 12.2 3.6 7.9 6.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) GMC_oxred_N PF00732.14 KFH42728.1 - 1.7e-26 93.0 0.1 5.7e-26 91.3 0.0 1.9 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFH42728.1 - 8.2e-25 87.7 0.0 1.3e-24 87.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KFH42728.1 - 4e-09 35.8 0.2 4.6e-05 22.4 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFH42728.1 - 6.8e-09 35.0 0.8 0.00013 21.0 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 KFH42728.1 - 6.5e-05 23.0 0.0 0.02 14.9 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFH42728.1 - 7.9e-05 22.6 0.0 0.00037 20.4 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KFH42728.1 - 9.6e-05 21.6 0.6 0.0028 16.8 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KFH42728.1 - 0.00016 20.2 0.0 0.0004 18.9 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 KFH42728.1 - 0.0012 17.8 0.3 0.0022 16.9 0.1 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KFH42728.1 - 0.0022 17.9 0.0 0.0041 17.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFH42728.1 - 0.0035 17.7 0.1 0.2 12.0 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFH42728.1 - 0.009 15.1 0.2 0.015 14.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KFH42728.1 - 0.047 12.7 0.3 0.09 11.8 0.2 1.4 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.13 KFH42728.1 - 0.089 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain GIDA PF01134.17 KFH42728.1 - 0.1 11.4 0.5 0.56 8.9 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Adaptin_N PF01602.15 KFH42729.1 - 7.1e-113 377.6 0.9 9.7e-113 377.2 0.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 KFH42729.1 - 2.7e-57 192.8 3.1 6.1e-57 191.6 2.2 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 KFH42729.1 - 2.7e-13 50.0 0.7 0.00039 20.6 0.1 5.8 2 1 3 5 5 5 4 HEAT repeats CLASP_N PF12348.3 KFH42729.1 - 0.0017 17.7 3.0 0.0089 15.4 0.2 2.9 3 0 0 3 3 3 1 CLASP N terminal Alpha_adaptin_C PF02296.11 KFH42729.1 - 0.011 15.7 0.0 0.048 13.6 0.0 2.2 2 0 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain HEAT_PBS PF03130.11 KFH42729.1 - 0.056 13.9 0.0 61 4.5 0.0 4.2 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat HEAT PF02985.17 KFH42729.1 - 0.17 12.0 7.4 0.74 10.0 0.1 4.9 5 0 0 5 5 5 0 HEAT repeat Spc24 PF08286.6 KFH42730.1 - 3.6e-41 139.5 0.6 1.6e-39 134.2 0.0 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Myosin_tail_1 PF01576.14 KFH42730.1 - 0.0022 15.8 3.2 0.0025 15.6 2.2 1.0 1 0 0 1 1 1 1 Myosin tail DUF4164 PF13747.1 KFH42730.1 - 0.0091 16.1 9.7 0.011 15.7 4.3 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4164) Troponin PF00992.15 KFH42730.1 - 0.03 14.3 1.4 0.046 13.7 1.0 1.3 1 0 0 1 1 1 0 Troponin Myb_Cef PF11831.3 KFH42730.1 - 0.047 12.9 0.7 0.47 9.6 0.5 2.0 1 1 0 1 1 1 0 pre-mRNA splicing factor component DUF4518 PF15008.1 KFH42730.1 - 0.11 11.4 0.4 2.8 6.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) CENP-F_leu_zip PF10473.4 KFH42730.1 - 0.16 11.8 3.4 0.28 11.0 2.3 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Vps5 PF09325.5 KFH42730.1 - 0.18 11.0 4.1 0.44 9.7 2.8 1.6 1 1 0 1 1 1 0 Vps5 C terminal like FUSC PF04632.7 KFH42730.1 - 1.1 7.6 6.7 1.2 7.5 4.7 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family IncA PF04156.9 KFH42730.1 - 1.8 8.1 9.2 3 7.4 6.4 1.4 1 1 0 1 1 1 0 IncA protein AMP-binding PF00501.23 KFH42732.1 - 1.2e-76 257.7 0.0 1.5e-76 257.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFH42732.1 - 3.5e-13 50.2 0.4 1.2e-12 48.5 0.3 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2577 PF10844.3 KFH42732.1 - 0.005 16.8 0.0 0.016 15.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2577) Fungal_trans PF04082.13 KFH42733.1 - 1e-23 83.5 1.2 1.5e-23 82.9 0.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH42733.1 - 2.5e-08 33.6 9.1 4.3e-08 32.9 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATP12 PF07542.6 KFH42734.1 - 2.5e-29 101.7 0.1 6e-29 100.4 0.0 1.7 2 0 0 2 2 2 1 ATP12 chaperone protein UnbV_ASPIC PF07593.7 KFH42734.1 - 0.049 13.3 0.2 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 ASPIC and UnbV RRM_1 PF00076.17 KFH42735.1 - 1.8e-20 72.3 0.0 2.4e-12 46.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH42735.1 - 1.6e-12 47.2 0.0 6.4e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH42735.1 - 0.00064 19.5 0.0 0.26 11.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TatD_DNase PF01026.16 KFH42736.1 - 5.4e-32 110.9 0.0 9.2e-32 110.2 0.0 1.3 1 1 0 1 1 1 1 TatD related DNase Toxin_47 PF15527.1 KFH42736.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative toxin 47 Lactamase_B_2 PF12706.2 KFH42737.1 - 2e-11 43.7 0.0 4.7e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KFH42737.1 - 1.8e-05 24.4 0.0 4.8e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DRMBL PF07522.9 KFH42737.1 - 3.8e-05 23.6 0.0 9.4e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase RMMBL PF07521.7 KFH42737.1 - 0.14 12.0 0.0 0.42 10.4 0.0 1.8 2 0 0 2 2 2 0 RNA-metabolising metallo-beta-lactamase TPR_MLP1_2 PF07926.7 KFH42738.1 - 2.6e-31 108.0 27.5 2.6e-31 108.0 19.1 17.3 7 4 9 17 17 17 7 TPR/MLP1/MLP2-like protein DUF904 PF06005.7 KFH42738.1 - 0.00029 21.0 5.3 0.00029 21.0 3.7 25.5 12 9 4 17 17 17 2 Protein of unknown function (DUF904) TACC PF05010.9 KFH42738.1 - 0.00063 19.5 16.4 0.00063 19.5 11.4 9.8 3 3 5 9 9 9 1 Transforming acidic coiled-coil-containing protein (TACC) Rootletin PF15035.1 KFH42738.1 - 0.00088 19.2 9.5 0.00088 19.2 6.6 15.8 4 3 11 15 15 15 2 Ciliary rootlet component, centrosome cohesion Lambda_tail_I PF06805.7 KFH42738.1 - 0.05 13.4 0.0 0.21 11.4 0.0 2.1 1 0 0 1 1 1 0 Bacteriophage lambda tail assembly protein I zf-MYND PF01753.13 KFH42739.1 - 4.2e-06 26.5 11.5 0.0014 18.4 0.7 2.7 2 0 0 2 2 2 2 MYND finger Ecl1 PF12855.2 KFH42739.1 - 0.0084 15.3 7.7 0.16 11.3 0.6 2.8 2 0 0 2 2 2 2 Life-span regulatory factor PHD PF00628.24 KFH42739.1 - 0.026 14.2 0.3 0.026 14.2 0.2 3.1 2 1 1 3 3 3 0 PHD-finger RPAP2_Rtr1 PF04181.8 KFH42739.1 - 0.095 12.8 6.6 6.6 6.9 2.5 2.6 1 1 1 2 2 2 0 Rtr1/RPAP2 family DUF329 PF03884.9 KFH42739.1 - 1.1 8.8 11.1 0.41 10.2 0.7 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF329) SQS_PSY PF00494.14 KFH42740.1 - 2.3e-64 217.2 0.3 3.5e-64 216.6 0.2 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF1213 PF06740.7 KFH42741.1 - 0.21 11.6 0.1 0.21 11.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1213) MT0933_antitox PF14013.1 KFH42741.1 - 0.3 11.2 3.2 0.74 9.9 2.2 1.8 1 0 0 1 1 1 0 MT0933-like antitoxin protein Dehydrin PF00257.14 KFH42741.1 - 1.2 9.4 10.8 1.9 8.8 7.3 1.5 1 1 0 1 1 1 0 Dehydrin MFS_1 PF07690.11 KFH42742.1 - 1.9e-38 132.0 26.8 1.9e-38 132.0 18.6 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH42742.1 - 8.2e-08 31.2 6.4 8.2e-08 31.2 4.4 1.8 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KFH42742.1 - 0.0047 15.1 2.3 0.0084 14.3 1.6 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) 2-Hacid_dh_C PF02826.14 KFH42743.1 - 1.4e-44 151.3 0.0 9.9e-30 102.9 0.0 2.1 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KFH42743.1 - 0.16 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding FR47 PF08445.5 KFH42744.1 - 2.2e-06 27.3 0.0 1.3e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.1 KFH42744.1 - 6.6e-05 23.0 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFH42744.1 - 0.0038 17.2 0.0 0.01 15.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family SR-25 PF10500.4 KFH42745.1 - 2.9 7.2 15.3 6.3 6.1 10.6 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Zip PF02535.17 KFH42745.1 - 5.9 5.7 10.2 8.6 5.2 7.1 1.5 1 1 0 1 1 1 0 ZIP Zinc transporter Dabb PF07876.7 KFH42746.1 - 5.4e-23 81.2 0.0 9.7e-23 80.4 0.0 1.4 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain Sporozoite_P67 PF05642.6 KFH42747.1 - 0.039 11.8 10.6 0.05 11.4 7.3 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF966 PF06136.8 KFH42747.1 - 0.47 9.8 5.9 0.63 9.4 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) TSP9 PF11493.3 KFH42747.1 - 1.8 9.1 4.7 1.2 9.7 1.4 2.1 1 1 1 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 FAM176 PF14851.1 KFH42747.1 - 2.6 7.7 5.1 4.7 6.8 3.6 1.5 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.7 KFH42747.1 - 3.6 5.3 12.6 4.7 5.0 8.8 1.0 1 0 0 1 1 1 0 Nop14-like family Pyridox_oxase_2 PF12766.2 KFH42749.1 - 2.9e-20 72.4 0.0 4.6e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase CFEM PF05730.6 KFH42750.1 - 7.3e-05 22.5 1.5 0.00026 20.7 1.0 1.9 1 0 0 1 1 1 1 CFEM domain Ras PF00071.17 KFH42751.1 - 3.5e-31 107.7 0.0 6.1e-24 84.2 0.0 2.0 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KFH42751.1 - 1.1e-07 32.2 0.0 4.8e-07 30.2 0.0 1.9 3 0 0 3 3 3 1 Miro-like protein Arf PF00025.16 KFH42751.1 - 0.05 12.8 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family Asp PF00026.18 KFH42753.1 - 9.1e-52 176.2 0.0 1.1e-51 175.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFH42753.1 - 2.2e-06 27.6 0.0 1.2e-05 25.2 0.0 2.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KFH42753.1 - 0.00018 21.9 0.2 0.53 10.8 0.1 3.4 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.1 KFH42753.1 - 0.0052 16.3 0.1 0.19 11.2 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal SF3b10 PF07189.6 KFH42754.1 - 1.8e-43 146.2 0.0 2e-43 146.0 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) DEAD PF00270.24 KFH42755.1 - 1.1e-41 142.1 0.0 3.8e-41 140.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFH42755.1 - 1.4e-22 79.2 0.0 4.7e-22 77.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KFH42755.1 - 0.01 14.6 0.0 0.016 13.9 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain ResIII PF04851.10 KFH42755.1 - 0.015 15.1 0.1 0.041 13.7 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Zn_clus PF00172.13 KFH42756.1 - 0.0027 17.5 11.2 0.0044 16.8 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_7 PF03441.9 KFH42757.1 - 1.3e-55 188.5 0.1 1.9e-55 188.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KFH42757.1 - 4.3e-21 75.3 0.0 7e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase NAD_binding_8 PF13450.1 KFH42759.1 - 1e-15 57.4 0.2 3e-15 55.9 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFH42759.1 - 3e-13 49.4 0.3 1.4e-12 47.2 0.1 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KFH42759.1 - 3e-13 49.6 0.8 8.4e-13 48.1 0.1 2.0 2 1 1 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 KFH42759.1 - 9.9e-07 27.9 3.5 1.1e-05 24.5 2.5 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KFH42759.1 - 2.1e-06 26.4 0.2 0.00051 18.6 0.7 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 KFH42759.1 - 3.2e-06 27.1 0.0 9.2e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KFH42759.1 - 2.3e-05 23.6 0.0 0.00012 21.2 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KFH42759.1 - 3.3e-05 24.0 0.0 0.00014 21.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFH42759.1 - 0.00022 20.3 0.8 0.00045 19.3 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KFH42759.1 - 0.00023 21.4 1.8 0.0014 19.0 0.9 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFH42759.1 - 0.00082 18.5 0.3 0.0015 17.6 0.2 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 KFH42759.1 - 0.0013 18.5 1.0 0.024 14.4 0.3 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KFH42759.1 - 0.0019 17.2 0.6 0.0038 16.1 0.4 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein ApbA PF02558.11 KFH42759.1 - 0.0053 16.2 0.7 0.013 14.9 0.5 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 KFH42759.1 - 0.048 12.5 3.2 0.16 10.8 1.9 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 KFH42759.1 - 0.05 13.2 0.8 0.083 12.5 0.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.1 KFH42759.1 - 0.071 13.4 0.0 0.4 10.9 0.0 2.2 2 0 0 2 2 2 0 XdhC Rossmann domain F420_oxidored PF03807.12 KFH42759.1 - 0.075 13.4 0.9 0.53 10.7 0.6 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 KFH42759.1 - 0.09 12.7 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.9 KFH42759.1 - 0.15 10.6 1.1 5.9 5.3 1.1 2.2 2 0 0 2 2 2 0 Tryptophan halogenase GDI PF00996.13 KFH42759.1 - 0.16 10.2 0.1 6.1 5.0 0.0 2.1 2 0 0 2 2 2 0 GDP dissociation inhibitor ThiF PF00899.16 KFH42759.1 - 0.17 11.7 0.3 0.32 10.7 0.2 1.5 1 0 0 1 1 1 0 ThiF family NAD_Gly3P_dh_N PF01210.18 KFH42759.1 - 0.17 11.5 0.1 0.37 10.4 0.1 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SLS PF14611.1 KFH42760.1 - 5.4e-26 91.3 0.4 2.5e-25 89.1 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator MHC_I_C PF06623.6 KFH42760.1 - 0.1 12.0 0.0 0.82 9.1 0.0 2.3 2 0 0 2 2 2 0 MHC_I C-terminus GTP_EFTU PF00009.22 KFH42761.1 - 9.7e-57 191.4 0.1 1.4e-56 190.9 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KFH42761.1 - 1.1e-35 121.6 0.0 2.7e-35 120.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KFH42761.1 - 4.2e-17 62.0 0.4 4.2e-17 62.0 0.3 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 KFH42761.1 - 0.00047 19.7 0.1 0.0012 18.4 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 KFH42761.1 - 0.0009 19.1 0.2 0.0033 17.3 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ank_5 PF13857.1 KFH42762.1 - 4.1e-06 26.8 0.0 9.7e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 KFH42762.1 - 0.0028 17.3 0.3 0.0089 15.7 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 KFH42762.1 - 0.013 15.7 0.0 0.029 14.7 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KFH42762.1 - 0.1 12.8 0.0 0.28 11.5 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeat DUF1674 PF07896.7 KFH42764.1 - 1.1e-16 60.7 7.2 2.3e-16 59.7 5.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Sugar_tr PF00083.19 KFH42765.1 - 3.3e-94 315.9 25.0 4.1e-94 315.7 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH42765.1 - 2.2e-22 79.2 17.9 2.2e-22 79.2 12.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_transf_34 PF05637.7 KFH42766.1 - 2.5e-08 33.7 1.1 3.8e-08 33.1 0.8 1.3 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.11 KFH42766.1 - 1.6e-05 24.7 0.0 6e-05 22.9 0.0 1.8 1 1 1 2 2 2 1 Nucleotide-diphospho-sugar transferase DUF273 PF03314.9 KFH42766.1 - 0.0016 17.7 0.1 0.0033 16.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF273 Glyco_transf_8 PF01501.15 KFH42766.1 - 0.028 13.7 0.4 0.054 12.8 0.3 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 8 DUF427 PF04248.7 KFH42767.1 - 4e-38 128.9 0.6 3.7e-28 97.0 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF427) MFS_1 PF07690.11 KFH42769.1 - 1.1e-14 53.9 3.2 1.3e-14 53.6 2.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH42769.1 - 1.1e-07 30.8 0.0 1.1e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KFH42769.1 - 0.00039 18.7 0.0 0.00042 18.6 0.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 KFH42769.1 - 0.0067 16.1 0.4 0.013 15.2 0.1 1.5 1 1 0 1 1 1 1 MFS_1 like family ATG22 PF11700.3 KFH42769.1 - 0.057 11.8 0.1 0.062 11.7 0.1 1.2 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like MFS_2 PF13347.1 KFH42769.1 - 0.08 11.3 0.6 0.096 11.0 0.4 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein DUF647 PF04884.9 KFH42770.1 - 1.9e-87 292.6 1.5 2.7e-87 292.1 1.0 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Lactamase_B PF00753.22 KFH42771.1 - 0.00011 21.8 0.1 0.00017 21.2 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF607 PF04678.8 KFH42772.1 - 3.1e-40 138.0 0.7 2.1e-39 135.2 0.5 2.3 1 1 0 1 1 1 1 Protein of unknown function, DUF607 NmrA PF05368.8 KFH42775.1 - 2.1e-25 89.3 0.0 2.9e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFH42775.1 - 1.6e-14 54.3 0.1 2.1e-14 53.9 0.1 1.1 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KFH42775.1 - 9.4e-05 21.5 0.1 0.00016 20.7 0.0 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase Epimerase PF01370.16 KFH42775.1 - 0.00013 21.4 0.1 0.0007 19.1 0.1 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFH42775.1 - 0.00067 18.4 0.1 0.0018 17.0 0.1 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF2005 PF09407.5 KFH42775.1 - 0.044 12.5 0.1 1.4 7.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2005) Succ_CoA_lig PF13607.1 KFH42775.1 - 0.049 13.2 0.6 11 5.6 0.3 2.7 2 1 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain Semialdhyde_dh PF01118.19 KFH42775.1 - 0.11 12.8 0.1 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Pyrophosphatase PF00719.14 KFH42778.1 - 3.5e-29 101.2 0.4 1.2e-15 57.2 0.0 3.1 1 1 2 3 3 3 2 Inorganic pyrophosphatase Lac_bphage_repr PF06543.7 KFH42778.1 - 0.19 11.2 2.1 0.88 9.1 0.2 2.5 2 0 0 2 2 2 0 Lactococcus bacteriophage repressor PNK3P PF08645.6 KFH42779.1 - 4.5e-54 182.1 0.0 7.1e-54 181.5 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 KFH42779.1 - 2e-33 115.2 0.0 1e-32 113.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFH42779.1 - 0.00031 19.8 0.0 0.0046 16.0 0.0 2.1 1 1 1 2 2 2 1 Zeta toxin AAA_22 PF13401.1 KFH42779.1 - 0.00082 19.5 0.0 0.0023 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFH42779.1 - 0.0019 19.0 0.1 0.0093 16.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 KFH42779.1 - 0.0025 17.0 0.2 0.58 9.3 0.0 2.3 1 1 1 2 2 2 2 Chromatin associated protein KTI12 DUF3046 PF11248.3 KFH42779.1 - 0.0041 17.0 0.1 0.52 10.3 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3046) RNA_helicase PF00910.17 KFH42779.1 - 0.021 14.9 0.0 0.08 13.1 0.0 1.9 2 0 0 2 2 2 0 RNA helicase HAD_2 PF13419.1 KFH42779.1 - 0.033 14.4 0.2 23 5.1 0.0 3.2 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase Rad17 PF03215.10 KFH42779.1 - 0.047 12.3 0.0 0.066 11.8 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DNA_pol3_delta2 PF13177.1 KFH42779.1 - 0.055 13.1 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_29 PF13555.1 KFH42779.1 - 0.059 12.8 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 KFH42779.1 - 0.082 13.2 0.5 6.2 7.1 0.1 2.4 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.1 KFH42779.1 - 0.14 12.0 0.0 0.4 10.6 0.0 1.8 2 1 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 KFH42779.1 - 0.16 11.1 0.0 0.35 10.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Macro_2 PF14519.1 KFH42781.1 - 0.014 14.5 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Macro-like domain tRNA-synt_1c PF00749.16 KFH42782.1 - 1.1e-96 323.2 0.0 1.3e-96 322.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KFH42782.1 - 6.5e-39 133.3 0.0 9.9e-39 132.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.14 KFH42782.1 - 0.0028 16.8 0.9 0.005 16.0 0.4 1.4 1 1 1 2 2 2 1 tRNA synthetases class I (C) catalytic domain DUF3043 PF11241.3 KFH42783.1 - 0.15 11.6 1.7 0.28 10.7 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Glyco_hydro_10 PF00331.15 KFH42785.1 - 4.4e-97 324.9 0.0 4.9e-97 324.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 EBA-175_VI PF11556.3 KFH42786.1 - 5.5 7.1 6.5 1.2 9.3 1.7 2.0 2 0 0 2 2 2 0 Erythrocyte binding antigen 175 Hid1 PF12722.2 KFH42786.1 - 9 3.8 9.1 11 3.5 6.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PHO4 PF01384.15 KFH42788.1 - 4.3e-112 373.9 9.5 5.4e-112 373.6 6.6 1.1 1 0 0 1 1 1 1 Phosphate transporter family CLN3 PF02487.12 KFH42790.1 - 7.7e-107 357.5 12.3 8.7e-104 347.4 8.5 2.2 1 1 0 1 1 1 1 CLN3 protein MFS_1 PF07690.11 KFH42790.1 - 0.055 12.1 30.5 0.22 10.2 7.7 2.9 1 1 1 2 2 2 0 Major Facilitator Superfamily GST_N_3 PF13417.1 KFH42791.1 - 7.4e-07 29.3 0.0 1.5e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFH42791.1 - 0.0001 22.2 0.0 0.00018 21.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFH42791.1 - 0.00021 21.1 0.0 0.0004 20.2 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KFH42791.1 - 0.00031 20.8 0.0 0.0042 17.2 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFH42791.1 - 0.012 15.5 0.2 0.082 12.8 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Cyto_heme_lyase PF01265.12 KFH42792.1 - 3.5e-85 285.7 1.3 3.9e-85 285.5 0.9 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase MFS_1 PF07690.11 KFH42793.1 - 3.5e-15 55.5 24.7 1.7e-10 40.2 2.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MttA_Hcf106 PF02416.11 KFH42793.1 - 0.24 10.5 2.0 0.53 9.4 1.4 1.6 1 0 0 1 1 1 0 mttA/Hcf106 family DUF4191 PF13829.1 KFH42793.1 - 4.8 6.2 8.1 4.1 6.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) GHMP_kinases_N PF00288.21 KFH42794.1 - 6.7e-10 38.8 1.9 2.4e-09 37.1 1.0 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KFH42794.1 - 0.037 14.2 0.1 0.15 12.2 0.0 2.1 3 0 0 3 3 3 0 GHMP kinases C terminal Acetyltransf_8 PF13523.1 KFH42795.1 - 4.7e-33 114.2 0.0 7.2e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3292 PF11696.3 KFH42796.1 - 1.2e-223 743.6 0.0 1.5e-223 743.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) Rxt3 PF08642.5 KFH42797.1 - 1.4e-26 92.9 2.3 1.9e-26 92.5 0.0 2.4 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 KFH42797.1 - 3.3e-05 23.7 0.0 0.0048 16.8 0.0 2.5 2 0 0 2 2 2 2 LCCL domain zf-C2H2_4 PF13894.1 KFH42798.1 - 8.7e-10 38.2 7.3 7.4e-05 22.8 0.1 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KFH42798.1 - 3.4e-08 33.3 10.0 4.6e-05 23.5 0.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type Fungal_trans PF04082.13 KFH42798.1 - 0.00024 20.0 0.0 0.0041 16.0 0.0 2.2 1 1 1 2 2 2 1 Fungal specific transcription factor domain zf-C2H2_jaz PF12171.3 KFH42798.1 - 0.0035 17.4 0.9 0.11 12.6 0.0 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 KFH42798.1 - 0.0076 16.4 0.5 0.0076 16.4 0.3 3.4 4 0 0 4 4 4 1 Zinc-finger double domain DUF4234 PF14018.1 KFH42800.1 - 0.077 12.7 3.2 0.91 9.3 0.9 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4234) Med18 PF09637.5 KFH42801.1 - 6.3e-24 84.8 0.0 7.9e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Med18 protein Sugar_tr PF00083.19 KFH42802.1 - 8.7e-79 265.1 22.3 1.1e-78 264.8 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH42802.1 - 2.3e-18 66.0 60.0 4.3e-15 55.2 21.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MgtE PF01769.11 KFH42802.1 - 0.046 14.0 4.2 0.075 13.3 0.1 2.5 2 0 0 2 2 2 0 Divalent cation transporter Lactamase_B_2 PF12706.2 KFH42803.1 - 1.5e-14 53.9 0.1 2.1e-14 53.5 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KFH42803.1 - 4.7e-08 32.9 0.4 7.7e-08 32.2 0.3 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Amidohydro_2 PF04909.9 KFH42803.1 - 0.036 13.6 0.0 0.076 12.5 0.0 1.7 1 1 0 1 1 1 0 Amidohydrolase Amidohydro_1 PF01979.15 KFH42804.1 - 3.5e-27 95.9 0.3 6.4e-26 91.7 0.2 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KFH42804.1 - 4.9e-15 55.1 0.0 1.4e-14 53.6 0.0 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 KFH42804.1 - 1.8e-09 38.0 4.4 1.2e-05 25.4 0.2 2.5 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 KFH42804.1 - 1.5e-08 34.3 5.2 5.8e-06 25.7 0.0 2.9 2 1 0 2 2 2 2 Amidohydrolase family Dynamin_N PF00350.18 KFH42805.1 - 8.1e-29 100.5 0.3 2.1e-28 99.2 0.0 1.9 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 KFH42805.1 - 2.1e-17 62.8 0.0 1.9e-13 49.9 0.0 2.3 1 1 1 2 2 2 2 Dynamin central region GED PF02212.13 KFH42805.1 - 1.5e-07 31.1 1.2 3.6e-07 29.9 0.1 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KFH42805.1 - 1.2e-05 25.2 0.0 0.00025 20.9 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KFH42805.1 - 0.0018 18.7 0.0 0.0053 17.2 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_21 PF13304.1 KFH42805.1 - 0.0071 16.3 0.1 0.025 14.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain FeoB_N PF02421.13 KFH42805.1 - 0.013 14.7 0.0 1.1 8.5 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_23 PF13476.1 KFH42805.1 - 0.047 14.0 2.7 0.35 11.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain SMC_N PF02463.14 KFH42805.1 - 0.055 12.6 0.0 0.15 11.2 0.0 1.7 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain PhzC-PhzF PF02567.11 KFH42807.1 - 6.3e-39 133.8 0.0 2e-38 132.2 0.0 1.7 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein NARP1 PF12569.3 KFH42810.1 - 9e-199 661.5 30.0 2.2e-197 656.9 16.7 2.3 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.1 KFH42810.1 - 2.7e-21 75.6 30.8 7.1e-05 23.0 0.1 8.0 7 1 1 8 8 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 KFH42810.1 - 3.9e-21 73.6 23.9 0.00044 20.6 0.1 10.9 8 3 4 12 12 11 4 Tetratricopeptide repeat TPR_16 PF13432.1 KFH42810.1 - 1.8e-20 73.0 32.8 1.4e-05 25.6 5.1 8.6 8 2 2 10 10 8 5 Tetratricopeptide repeat TPR_11 PF13414.1 KFH42810.1 - 8.3e-20 70.2 31.0 1.4e-06 27.8 0.4 7.0 4 1 4 8 8 8 7 TPR repeat TPR_2 PF07719.12 KFH42810.1 - 2.1e-19 67.7 24.9 0.00014 21.5 0.2 9.7 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_1 PF00515.23 KFH42810.1 - 1.4e-16 59.2 20.6 1.6e-05 24.2 0.4 8.3 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.1 KFH42810.1 - 5e-12 45.0 14.0 0.0078 16.3 0.0 9.2 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.1 KFH42810.1 - 1.4e-11 44.0 12.8 0.00065 19.5 0.4 5.9 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFH42810.1 - 1.5e-10 40.8 29.5 0.0027 17.5 0.1 7.7 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 KFH42810.1 - 4.5e-05 22.9 23.5 0.0036 16.9 0.1 7.7 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFH42810.1 - 7.3e-05 22.2 15.7 3.4 7.6 0.0 7.2 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_15 PF13429.1 KFH42810.1 - 0.00018 20.6 20.2 0.035 13.1 2.8 4.7 3 1 1 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 KFH42810.1 - 0.00032 20.9 25.1 0.75 10.3 0.1 8.2 9 0 0 9 9 6 3 Tetratricopeptide repeat TPR_4 PF07721.9 KFH42810.1 - 0.00091 19.4 7.4 0.47 11.0 0.1 5.4 4 0 0 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.12 KFH42810.1 - 0.0088 16.3 2.1 0.0088 16.3 1.4 3.9 3 2 2 5 5 3 1 Bacterial transcriptional activator domain TPR_10 PF13374.1 KFH42810.1 - 0.0093 15.8 20.1 1.7 8.7 0.0 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat Sel1 PF08238.7 KFH42810.1 - 0.019 15.5 7.9 0.52 11.0 0.1 3.9 3 0 0 3 3 3 0 Sel1 repeat TPR_3 PF07720.7 KFH42810.1 - 0.14 11.9 0.2 0.14 11.9 0.1 4.8 6 0 0 6 6 5 0 Tetratricopeptide repeat CTV_P13 PF06922.6 KFH42811.1 - 0.17 11.7 0.6 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Citrus tristeza virus P13 protein RNA_lig_T4_1 PF09511.5 KFH42813.1 - 4.4e-80 268.3 0.0 7.9e-80 267.4 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.6 KFH42813.1 - 3.1e-74 249.4 0.1 4.5e-74 248.9 0.1 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.6 KFH42813.1 - 3.8e-55 186.3 0.0 9.5e-55 185.0 0.0 1.7 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_17 PF13207.1 KFH42813.1 - 0.016 15.9 0.0 0.28 12.0 0.0 2.8 2 2 0 2 2 2 0 AAA domain Ribosomal_S11 PF00411.14 KFH42814.1 - 2.3e-08 34.1 0.0 5.2e-08 33.0 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S11 Vac_ImportDeg PF09783.4 KFH42816.1 - 9.8e-70 233.6 1.1 1.4e-69 233.1 0.7 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Ribonuc_P_40 PF08584.6 KFH42817.1 - 4.1e-65 219.6 0.0 5.4e-65 219.2 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Cyt-b5 PF00173.23 KFH42819.1 - 6e-13 48.4 0.0 8.1e-13 47.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AA_permease PF00324.16 KFH42820.1 - 3.9e-117 391.5 40.8 4.4e-117 391.3 28.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFH42820.1 - 8e-30 103.7 45.8 1.1e-29 103.3 31.8 1.0 1 0 0 1 1 1 1 Amino acid permease Adaptin_N PF01602.15 KFH42821.1 - 4.8e-91 305.6 8.8 4.8e-91 305.6 6.1 1.5 2 0 0 2 2 2 1 Adaptin N terminal region Coatamer_beta_C PF07718.7 KFH42821.1 - 5.6e-63 210.7 1.1 1.2e-62 209.7 0.8 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.1 KFH42821.1 - 5.9e-63 210.3 0.0 1.9e-62 208.7 0.0 1.9 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform HEAT_2 PF13646.1 KFH42821.1 - 9.1e-11 41.8 7.6 5.2e-07 29.8 0.0 4.5 3 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.2 KFH42821.1 - 0.00011 22.0 5.8 0.01 15.6 0.0 4.1 2 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KFH42821.1 - 0.0019 18.1 0.3 0.78 9.9 0.0 4.2 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 KFH42821.1 - 0.0035 17.7 3.1 1.9 9.0 0.0 5.0 5 1 0 5 5 5 1 HEAT-like repeat Oxysterol_BP PF01237.13 KFH42822.1 - 6.1e-90 301.2 0.0 7.3e-90 301.0 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein AAA PF00004.24 KFH42823.1 - 9.6e-40 135.8 0.0 1.8e-39 134.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFH42823.1 - 0.00016 21.3 0.1 0.00077 19.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KFH42823.1 - 0.0002 21.4 0.1 0.012 15.5 0.0 2.6 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 KFH42823.1 - 0.0003 19.9 0.0 0.00064 18.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KFH42823.1 - 0.00043 20.4 0.1 0.019 15.1 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 KFH42823.1 - 0.0012 18.8 0.0 0.0089 15.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) PhoH PF02562.11 KFH42823.1 - 0.0051 16.0 0.3 0.044 13.0 0.1 2.1 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 KFH42823.1 - 0.0062 15.7 0.1 0.017 14.3 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 KFH42823.1 - 0.0073 15.2 0.0 0.016 14.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 KFH42823.1 - 0.012 15.5 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KFH42823.1 - 0.017 14.8 0.4 0.044 13.5 0.3 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 KFH42823.1 - 0.023 14.0 0.1 0.047 13.1 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 KFH42823.1 - 0.037 13.4 1.3 0.32 10.3 0.2 2.2 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 KFH42823.1 - 0.055 13.0 0.1 0.14 11.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KFH42823.1 - 0.087 13.6 2.6 0.089 13.6 0.1 2.4 2 2 0 2 2 2 0 AAA domain BCS1_N PF08740.6 KFH42824.1 - 3.2e-40 137.7 0.0 4.6e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KFH42824.1 - 1.4e-17 64.0 0.0 2.3e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KFH42824.1 - 1.1e-05 26.2 0.0 2.6e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KFH42824.1 - 3.8e-05 23.1 0.0 0.00024 20.5 0.0 2.2 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.1 KFH42824.1 - 0.001 18.9 0.0 0.0038 17.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KFH42824.1 - 0.0018 18.0 0.0 0.0038 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KFH42824.1 - 0.0024 16.9 0.0 0.0053 15.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 KFH42824.1 - 0.0033 16.9 0.0 0.0086 15.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KFH42824.1 - 0.0038 17.3 0.0 0.008 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 KFH42824.1 - 0.0057 15.6 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 KFH42824.1 - 0.011 15.9 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_21 PF13304.1 KFH42824.1 - 0.016 15.1 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KFH42824.1 - 0.016 15.1 0.1 0.11 12.4 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.7 KFH42824.1 - 0.02 13.9 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 KFH42824.1 - 0.024 14.9 0.0 0.052 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 KFH42824.1 - 0.03 14.8 0.0 0.059 13.8 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein DUF258 PF03193.11 KFH42824.1 - 0.038 13.1 0.0 0.086 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AFOR_C PF01314.13 KFH42824.1 - 0.039 12.6 0.0 0.059 12.0 0.0 1.1 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 MMR_HSR1 PF01926.18 KFH42824.1 - 0.064 13.2 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 KFH42824.1 - 0.08 13.1 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ATP_bind_1 PF03029.12 KFH42824.1 - 0.097 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein FMN_bind PF04205.9 KFH42824.1 - 0.14 12.3 0.0 0.42 10.8 0.0 1.8 2 0 0 2 2 1 0 FMN-binding domain GTSE1_N PF15259.1 KFH42824.1 - 0.21 11.5 0.0 0.34 10.8 0.0 1.2 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 p450 PF00067.17 KFH42825.1 - 1.7e-75 254.3 0.0 2.1e-75 254.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Lipase_GDSL_2 PF13472.1 KFH42826.1 - 2.1e-18 67.0 1.1 3.7e-18 66.2 0.7 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFH42826.1 - 2.5e-15 56.9 0.4 1.9e-14 54.0 0.3 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Aldolase_II PF00596.16 KFH42826.1 - 0.0032 17.0 0.0 0.016 14.8 0.0 1.9 2 0 0 2 2 2 1 Class II Aldolase and Adducin N-terminal domain Cro PF09048.5 KFH42828.1 - 0.073 12.7 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Cro Enolase_C PF00113.17 KFH42829.1 - 5.2e-154 511.5 0.1 6.7e-154 511.1 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 KFH42829.1 - 8.4e-58 194.0 0.2 1.3e-57 193.4 0.2 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.6 KFH42829.1 - 0.017 14.0 0.5 0.3 9.9 0.1 2.5 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus MR_MLE_C PF13378.1 KFH42829.1 - 0.021 14.8 0.0 0.057 13.3 0.0 1.7 2 0 0 2 2 2 0 Enolase C-terminal domain-like MR_MLE PF01188.16 KFH42829.1 - 0.059 13.9 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Peptidase_C97 PF05903.9 KFH42830.1 - 5.6e-31 107.3 0.0 7.4e-31 106.9 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 KFH42830.1 - 0.00012 22.0 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 Lecithin retinol acyltransferase DUF778 PF05608.7 KFH42830.1 - 0.12 12.2 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF778) Tim44 PF04280.10 KFH42831.1 - 6.2e-34 117.0 0.1 5.9e-33 113.9 0.0 2.3 2 0 0 2 2 2 1 Tim44-like domain DUF4369 PF14289.1 KFH42831.1 - 0.054 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4369) Daxx PF03344.10 KFH42831.1 - 1.7 7.0 17.4 2.5 6.5 12.0 1.2 1 0 0 1 1 1 0 Daxx Family Glyco_hydro_31 PF01055.21 KFH42832.1 - 6.9e-162 539.2 6.6 8.6e-162 538.9 4.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KFH42832.1 - 4.2e-11 42.5 0.2 1.7e-10 40.5 0.1 2.2 1 0 0 1 1 1 1 Galactose mutarotase-like Vps35 PF03635.12 KFH42834.1 - 1.3e-301 1002.3 0.0 1.6e-301 1002.1 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Tic20 PF09685.5 KFH42835.1 - 3.1e-07 30.3 5.3 4.7e-07 29.7 3.7 1.1 1 0 0 1 1 1 1 Tic20-like protein Reticulon PF02453.12 KFH42835.1 - 0.0052 16.4 0.3 0.0071 15.9 0.2 1.1 1 0 0 1 1 1 1 Reticulon UPF0020 PF01170.13 KFH42836.1 - 1.5e-10 40.9 0.0 2.4e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 KFH42836.1 - 1e-07 31.9 0.0 1.8e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KFH42836.1 - 0.057 13.0 0.0 0.19 11.2 0.0 1.8 2 0 0 2 2 2 0 Met-10+ like-protein Ank_5 PF13857.1 KFH42837.1 - 7.8e-11 41.8 0.1 2.7e-08 33.7 0.2 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFH42837.1 - 1.5e-07 31.6 0.0 2.6e-05 24.6 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFH42837.1 - 5.8e-05 22.9 2.0 0.0015 18.6 0.3 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.2 KFH42837.1 - 0.00016 21.9 0.4 0.0014 18.9 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFH42837.1 - 0.0021 17.7 0.4 0.026 14.3 0.2 2.4 2 0 0 2 2 2 1 Ankyrin repeat DALR_2 PF09190.6 KFH42837.1 - 0.013 15.7 0.0 0.059 13.6 0.0 2.1 2 1 0 2 2 2 0 DALR domain GCV_T PF01571.16 KFH42837.1 - 0.014 14.7 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain DAGK_cat PF00781.19 KFH42838.1 - 8.4e-29 99.6 0.1 1.4e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain SET PF00856.23 KFH42839.1 - 3.4e-23 82.7 0.0 2e-22 80.2 0.0 2.1 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 KFH42839.1 - 6.1e-06 26.4 2.3 5.4e-05 23.3 0.9 2.2 2 0 0 2 2 2 1 Pre-SET motif TFR_dimer PF04253.10 KFH42840.1 - 6e-20 71.0 0.1 4.6e-15 55.3 0.0 2.4 2 0 0 2 2 2 2 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 KFH42840.1 - 2.6e-16 59.8 0.0 1.5e-15 57.4 0.0 2.2 2 1 1 3 3 3 1 Peptidase family M28 PA PF02225.17 KFH42840.1 - 1.8e-07 30.7 0.1 4e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.10 KFH42840.1 - 0.027 13.7 0.0 0.065 12.4 0.0 1.6 1 0 0 1 1 1 0 Nicastrin Peptidase_M20 PF01546.23 KFH42840.1 - 0.083 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Mago_nashi PF02792.9 KFH42841.1 - 9.7e-71 236.0 0.2 1.1e-70 235.8 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein DUF2263 PF10021.4 KFH42842.1 - 2.9e-28 98.7 0.0 5.4e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Ribosomal_L10 PF00466.15 KFH42843.1 - 0.00075 19.3 0.0 0.0089 15.9 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L10 Cid2 PF09774.4 KFH42844.1 - 1.6e-47 161.4 0.0 1.8e-47 161.1 0.0 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Ish1 PF10281.4 KFH42845.1 - 1.8e-72 238.9 26.1 2.8e-13 49.6 0.1 8.5 8 0 0 8 8 8 8 Putative stress-responsive nuclear envelope protein SAP PF02037.22 KFH42845.1 - 7.6e-10 38.0 0.0 5 6.7 0.0 8.1 9 0 0 9 9 9 2 SAP domain Slx4 PF09494.5 KFH42845.1 - 1.2e-07 31.3 1.4 9.5 6.0 0.0 5.9 6 0 0 6 6 6 2 Slx4 endonuclease APC2 PF08672.6 KFH42845.1 - 8e-05 22.8 1.6 13 6.1 0.0 6.4 7 0 0 7 7 7 1 Anaphase promoting complex (APC) subunit 2 HeH PF12949.2 KFH42845.1 - 0.00024 20.5 0.0 4.6 6.8 0.0 5.2 6 0 0 6 6 6 1 HeH/LEM domain SAM_2 PF07647.12 KFH42845.1 - 0.071 12.9 0.4 2.1 8.2 0.0 3.3 4 0 0 4 4 4 0 SAM domain (Sterile alpha motif) LEA_4 PF02987.11 KFH42845.1 - 2.4 8.0 27.3 2.4 8.0 0.5 5.1 5 0 0 5 5 5 0 Late embryogenesis abundant protein F_bP_aldolase PF01116.15 KFH42846.1 - 2.4e-96 322.2 0.0 2.7e-96 322.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II VPS9 PF02204.13 KFH42847.1 - 2.4e-19 69.2 0.2 5.7e-19 68.0 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.1 KFH42847.1 - 7.5e-16 57.8 0.8 1.9e-11 43.8 0.0 5.2 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KFH42847.1 - 1.4e-12 47.7 0.0 3.9e-05 23.8 0.0 3.1 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KFH42847.1 - 6.4e-09 35.2 0.1 0.085 13.1 0.0 5.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 KFH42847.1 - 4.8e-08 33.2 0.2 0.0036 17.7 0.0 5.2 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank PF00023.25 KFH42847.1 - 2.7e-05 23.7 1.5 0.038 13.7 0.0 4.9 5 1 0 5 5 5 1 Ankyrin repeat PX PF00787.19 KFH42847.1 - 0.0044 16.7 0.5 0.01 15.6 0.0 1.9 2 0 0 2 2 2 1 PX domain BOP1NT PF08145.7 KFH42848.1 - 9.4e-107 356.5 5.9 1.3e-106 356.1 4.1 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 KFH42848.1 - 9.1e-28 95.1 6.8 1.5e-10 40.5 0.3 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat SAC3_GANP PF03399.11 KFH42849.1 - 0.00019 21.0 0.4 0.0048 16.4 0.2 2.1 1 1 0 2 2 2 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KFH42849.1 - 0.027 14.2 0.0 0.043 13.5 0.0 1.5 1 1 0 1 1 1 0 COP9 signalosome, subunit CSN8 Se-cys_synth_N PF12390.3 KFH42849.1 - 0.082 13.0 0.1 0.27 11.3 0.0 1.9 2 0 0 2 2 2 0 Selenocysteine synthase N terminal YchF-GTPase_C PF06071.8 KFH42850.1 - 1.5e-33 114.4 0.3 4.3e-33 112.9 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 KFH42850.1 - 7.1e-12 45.3 0.0 1.8e-11 43.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 KFH42850.1 - 2.7e-05 23.8 0.0 7.1e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 TGS domain AAA_18 PF13238.1 KFH42850.1 - 0.005 17.1 1.7 2.7 8.2 0.9 2.9 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 KFH42850.1 - 0.024 14.3 0.5 3.2 7.4 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FeoB_N PF02421.13 KFH42850.1 - 0.027 13.7 0.0 0.058 12.6 0.0 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B BetaGal_dom3 PF13363.1 KFH42850.1 - 0.035 13.4 0.0 0.073 12.4 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 Dynamin_N PF00350.18 KFH42850.1 - 0.044 13.6 0.5 3.3 7.5 0.0 3.0 1 1 1 3 3 3 0 Dynamin family AKAP95 PF04988.7 KFH42850.1 - 0.058 13.1 0.2 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) ABC_tran PF00005.22 KFH42850.1 - 0.082 13.2 0.9 1.7 8.9 0.0 2.5 2 1 0 2 2 2 0 ABC transporter AAA_23 PF13476.1 KFH42850.1 - 7.9 6.7 9.5 86 3.3 6.6 2.5 1 1 0 1 1 1 0 AAA domain zf-DHHC PF01529.15 KFH42851.1 - 3.8e-40 137.1 0.8 7e-40 136.2 0.6 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase CFEM PF05730.6 KFH42852.1 - 8.6e-09 35.0 4.5 1.2e-08 34.6 3.1 1.2 1 0 0 1 1 1 1 CFEM domain OB_NTP_bind PF07717.11 KFH42853.1 - 2.1e-29 101.6 0.0 1.1e-28 99.3 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KFH42853.1 - 4.1e-28 97.3 0.0 4.1e-28 97.3 0.0 2.7 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KFH42853.1 - 5.7e-12 45.3 0.0 1.3e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 KFH42853.1 - 8.5e-10 38.5 0.2 1.6e-09 37.7 0.2 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 KFH42853.1 - 6.9e-07 28.9 0.1 1.7e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KFH42853.1 - 1.3e-05 25.3 0.0 4.1e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KFH42853.1 - 4.1e-05 22.6 0.1 0.00015 20.7 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.1 KFH42853.1 - 0.001 18.7 0.1 0.004 16.8 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 KFH42853.1 - 0.018 14.9 0.2 0.21 11.4 0.1 2.3 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 KFH42853.1 - 0.021 14.8 0.0 0.13 12.2 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.22 KFH42853.1 - 0.078 13.2 0.0 0.38 11.0 0.0 2.3 1 0 0 1 1 1 0 ABC transporter Myosin_head PF00063.16 KFH42853.1 - 0.11 10.5 0.0 0.19 9.7 0.0 1.3 1 0 0 1 1 1 0 Myosin head (motor domain) Herpes_ori_bp PF02399.10 KFH42853.1 - 0.26 9.2 0.0 0.41 8.5 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein DUF1509 PF07420.6 KFH42853.1 - 1.2 8.3 13.5 2.3 7.4 9.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) TP_methylase PF00590.15 KFH42855.1 - 3.9e-42 144.3 0.2 6.4e-42 143.6 0.2 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 KFH42855.1 - 1.3e-12 47.8 0.0 2.8e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 KFH42855.1 - 8.8e-10 37.7 0.5 1e-05 24.6 0.0 3.1 3 0 0 3 3 3 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 KFH42855.1 - 2e-05 23.4 0.0 3.8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central DUF2325 PF10087.4 KFH42855.1 - 0.073 12.9 0.1 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) UPF0731 PF14982.1 KFH42856.1 - 0.094 12.6 0.2 0.094 12.6 0.2 1.1 1 0 0 1 1 1 0 UPF0731 family DUF619 PF04768.8 KFH42857.1 - 1.6e-43 148.0 0.0 2.9e-43 147.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF619) AA_kinase PF00696.23 KFH42857.1 - 2e-28 99.5 0.0 3.3e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family Zn_clus PF00172.13 KFH42859.1 - 2.9e-07 30.3 10.8 2.9e-07 30.3 7.5 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 KFH42860.1 - 0.06 13.2 6.6 0.11 12.4 4.6 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4606 PF15379.1 KFH42860.1 - 0.29 11.2 2.0 2.3 8.3 1.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4606) Dickkopf_N PF04706.7 KFH42860.1 - 1.9 8.7 7.9 0.14 12.3 2.0 1.7 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region E1-E2_ATPase PF00122.15 KFH42861.1 - 2e-47 161.1 8.8 3.6e-47 160.3 6.1 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KFH42861.1 - 2e-27 97.0 0.2 4e-27 96.0 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFH42861.1 - 4.1e-14 53.2 0.0 8.9e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KFH42861.1 - 0.00017 21.6 0.4 0.0011 19.0 0.0 2.4 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 KFH42861.1 - 0.0026 17.3 0.7 0.0096 15.5 0.2 2.0 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Clp1 PF06807.9 KFH42863.1 - 1.2e-23 83.8 0.0 2e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 KFH42863.1 - 3.6e-07 29.9 0.0 1.2e-06 28.2 0.0 1.9 1 1 1 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 KFH42863.1 - 2e-05 24.2 0.1 5.6e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 KFH42863.1 - 3.6e-05 23.8 0.0 0.00013 22.0 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.18 KFH42863.1 - 4e-05 23.5 0.0 0.00019 21.3 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase CbiA PF01656.18 KFH42863.1 - 0.0011 18.3 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.17 KFH42863.1 - 0.0019 17.6 0.0 0.21 11.0 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain KTI12 PF08433.5 KFH42863.1 - 0.0028 16.9 0.0 0.1 11.8 0.0 2.2 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 KFH42863.1 - 0.0028 18.4 0.0 0.01 16.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KFH42863.1 - 0.0058 16.0 0.0 0.65 9.3 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_31 PF13614.1 KFH42863.1 - 0.0092 15.9 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFH42863.1 - 0.014 15.7 0.0 0.065 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain NAD_binding_10 PF13460.1 KFH42863.1 - 0.019 14.9 0.6 0.066 13.2 0.1 2.0 2 0 0 2 2 2 0 NADH(P)-binding AAA_14 PF13173.1 KFH42863.1 - 0.028 14.3 0.0 0.084 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KFH42863.1 - 0.03 13.8 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.1 KFH42863.1 - 0.033 14.3 0.0 0.07 13.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain ArgK PF03308.11 KFH42863.1 - 0.037 12.7 0.0 0.08 11.7 0.0 1.5 1 0 0 1 1 1 0 ArgK protein ATP-synt_ab PF00006.20 KFH42863.1 - 0.058 12.8 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_10 PF12846.2 KFH42863.1 - 0.06 12.7 0.0 0.12 11.7 0.0 1.5 2 0 0 2 2 1 0 AAA-like domain ArsA_ATPase PF02374.10 KFH42863.1 - 0.062 12.3 0.0 0.099 11.6 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase Sigma54_activat PF00158.21 KFH42863.1 - 0.072 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.24 KFH42863.1 - 0.13 12.4 0.1 0.76 9.9 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DAP3 PF10236.4 KFH42863.1 - 0.16 10.8 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Arch_ATPase PF01637.13 KFH42863.1 - 0.16 11.6 0.0 2.2 7.9 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase RNA_helicase PF00910.17 KFH42863.1 - 0.18 12.0 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.1 KFH42863.1 - 0.25 10.8 1.4 0.33 10.5 0.1 1.8 2 0 0 2 2 2 0 AAA domain Glyco_hydro_76 PF03663.9 KFH42864.1 - 0.18 11.1 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 76 Thioredoxin PF00085.15 KFH42865.1 - 8e-27 92.9 0.1 1.8e-26 91.8 0.1 1.5 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 KFH42865.1 - 1.2e-06 28.5 0.0 1.8e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 KFH42865.1 - 5.5e-05 22.8 0.0 0.00016 21.3 0.0 1.6 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_2 PF13098.1 KFH42865.1 - 6.8e-05 23.0 0.1 0.0003 20.9 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 KFH42865.1 - 0.00033 20.2 0.1 0.00051 19.6 0.1 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.1 KFH42865.1 - 0.013 15.4 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.1 KFH42865.1 - 0.035 13.6 0.0 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Radical_SAM PF04055.16 KFH42866.1 - 9.4e-11 42.1 0.0 1.5e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer2_3 PF13085.1 KFH42867.1 - 3.3e-33 113.7 0.0 6.2e-33 112.9 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 KFH42867.1 - 1.7e-09 37.8 6.5 1.7e-09 37.8 4.5 2.5 3 0 0 3 3 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 KFH42867.1 - 2.4e-09 37.0 4.5 2.4e-09 37.0 3.1 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 KFH42867.1 - 3.7e-05 23.4 3.9 3.7e-05 23.4 2.7 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 KFH42867.1 - 4.2e-05 23.8 1.6 4.2e-05 23.8 1.1 2.8 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 KFH42867.1 - 6.8e-05 23.0 5.3 0.028 14.6 0.8 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.22 KFH42867.1 - 0.0021 17.7 3.6 0.003 17.2 0.3 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 KFH42867.1 - 0.0089 16.3 6.1 0.0089 16.3 4.2 2.5 2 1 1 3 3 3 2 4Fe-4S dicluster domain DNA_pol3_tau_4 PF12168.3 KFH42867.1 - 0.3 11.5 3.0 0.5 10.8 0.4 2.2 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Fer4_15 PF13459.1 KFH42867.1 - 3.8 8.1 6.7 1.3 9.6 0.1 2.6 3 0 0 3 3 2 0 4Fe-4S single cluster domain Fer4_2 PF12797.2 KFH42867.1 - 4 7.5 18.0 1.7 8.7 3.1 3.4 3 0 0 3 3 3 0 4Fe-4S binding domain PAPS_reduct PF01507.14 KFH42868.1 - 2.1e-38 131.8 0.0 2.8e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DUF1690 PF07956.6 KFH42869.1 - 2.9e-33 114.8 4.1 3.5e-33 114.5 2.9 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) HK97-gp10_like PF04883.7 KFH42869.1 - 0.0049 17.7 0.7 0.0049 17.7 0.5 2.0 2 0 0 2 2 2 1 Bacteriophage HK97-gp10, putative tail-component Myosin_head PF00063.16 KFH42869.1 - 0.04 11.9 0.3 0.049 11.6 0.2 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) DUF2317 PF10079.4 KFH42869.1 - 0.11 11.1 3.3 0.14 10.7 2.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) PAD_N PF08526.5 KFH42869.1 - 0.12 12.4 0.1 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) N-terminal domain DUF3708 PF12501.3 KFH42869.1 - 0.12 12.2 2.1 0.17 11.6 1.5 1.2 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter Syntaxin_2 PF14523.1 KFH42869.1 - 0.2 11.7 2.9 0.2 11.7 1.0 1.9 2 1 0 2 2 2 0 Syntaxin-like protein NAD_binding_5 PF07994.7 KFH42869.1 - 0.86 9.0 3.9 0.52 9.7 1.4 1.5 1 1 1 2 2 2 0 Myo-inositol-1-phosphate synthase FUSC PF04632.7 KFH42869.1 - 1.2 7.5 3.4 1.4 7.2 2.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-H PF05837.7 KFH42869.1 - 1.3 9.2 8.9 0.31 11.2 3.1 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Corona_nucleoca PF00937.13 KFH42869.1 - 1.9 7.3 6.6 2.3 7.0 4.6 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein YtxH PF12732.2 KFH42869.1 - 5.8 7.3 8.4 9.8 6.6 0.5 2.6 1 1 1 2 2 2 0 YtxH-like protein CDC37_N PF03234.9 KFH42869.1 - 6.5 7.0 8.9 1.3 9.2 2.2 2.2 1 1 0 2 2 2 0 Cdc37 N terminal kinase binding DUF4404 PF14357.1 KFH42869.1 - 8.6 6.8 8.1 6.5 7.2 3.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) ABC_tran PF00005.22 KFH42870.1 - 2.5e-49 167.0 0.0 3e-27 95.5 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KFH42870.1 - 3.3e-15 56.8 6.2 1.9e-06 28.0 0.6 4.0 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 KFH42870.1 - 1.5e-14 53.7 0.0 4.7e-06 25.9 0.0 3.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KFH42870.1 - 1.1e-07 32.4 0.6 0.0013 19.1 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 KFH42870.1 - 1.6e-07 30.7 0.5 0.0084 15.6 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.1 KFH42870.1 - 3.4e-07 29.6 0.0 0.096 11.7 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 KFH42870.1 - 5.1e-07 29.0 0.0 0.0017 17.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KFH42870.1 - 7.2e-07 29.1 0.0 0.017 15.0 0.0 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 KFH42870.1 - 1.9e-06 28.7 0.7 0.028 15.2 0.5 3.1 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KFH42870.1 - 6.8e-06 26.2 0.6 0.26 11.4 0.0 4.1 3 1 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 KFH42870.1 - 1.2e-05 25.0 0.0 0.3 11.0 0.0 3.1 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Miro PF08477.8 KFH42870.1 - 3.1e-05 24.4 0.0 0.06 13.8 0.0 3.0 2 0 0 2 2 2 1 Miro-like protein AAA_10 PF12846.2 KFH42870.1 - 9.7e-05 21.9 2.4 0.8 9.0 0.1 3.8 4 0 0 4 4 4 2 AAA-like domain MobB PF03205.9 KFH42870.1 - 0.00011 21.9 0.1 0.19 11.4 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Chromo PF00385.19 KFH42870.1 - 0.00012 21.6 0.4 0.00034 20.2 0.1 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain NACHT PF05729.7 KFH42870.1 - 0.00041 20.0 0.2 0.3 10.7 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 KFH42870.1 - 0.00044 20.1 0.0 0.76 9.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 KFH42870.1 - 0.00069 19.6 0.0 0.034 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KFH42870.1 - 0.00087 19.6 0.0 0.077 13.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KFH42870.1 - 0.00092 19.3 0.0 2.1 8.5 0.0 2.7 2 0 0 2 2 2 2 RNA helicase ArgK PF03308.11 KFH42870.1 - 0.001 17.9 0.4 0.26 10.0 0.1 2.5 2 0 0 2 2 2 1 ArgK protein AAA_30 PF13604.1 KFH42870.1 - 0.0011 18.6 0.1 1.4 8.4 0.0 3.2 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.12 KFH42870.1 - 0.0014 18.5 0.8 0.62 9.8 0.0 3.4 3 0 0 3 3 2 1 Domain of unknown function DUF87 AAA_25 PF13481.1 KFH42870.1 - 0.0018 17.6 0.0 1.3 8.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.1 KFH42870.1 - 0.0035 15.8 0.0 1.4 7.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 KFH42870.1 - 0.0053 16.9 0.0 4.5 7.4 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 KFH42870.1 - 0.0099 15.7 0.0 0.4 10.4 0.0 2.9 2 1 1 3 3 3 1 Dynamin family PduV-EutP PF10662.4 KFH42870.1 - 0.013 14.9 0.0 1.1 8.7 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.13 KFH42870.1 - 0.024 14.1 0.9 5.7 6.3 0.0 3.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family DUF815 PF05673.8 KFH42870.1 - 0.028 13.3 0.0 1.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_16 PF13191.1 KFH42870.1 - 0.044 13.7 3.3 4.8 7.1 0.1 3.9 3 0 0 3 3 3 0 AAA ATPase domain AAA_14 PF13173.1 KFH42870.1 - 0.051 13.4 0.0 6.3 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KFH42870.1 - 0.059 13.0 0.2 7.8 6.1 0.0 2.8 3 0 0 3 3 2 0 Archaeal ATPase MutS_V PF00488.16 KFH42870.1 - 0.066 12.6 0.1 5.9 6.2 0.0 2.4 2 0 0 2 2 2 0 MutS domain V DUF3584 PF12128.3 KFH42870.1 - 0.085 10.1 1.1 2.7 5.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) cobW PF02492.14 KFH42870.1 - 0.092 12.1 0.1 18 4.7 0.0 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ketoacyl-synt PF00109.21 KFH42871.1 - 4.8e-71 239.2 1.1 1.1e-70 238.0 0.8 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KFH42871.1 - 1.1e-56 192.4 0.5 1.7e-56 191.8 0.3 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KFH42871.1 - 1.3e-53 182.1 0.0 2.1e-53 181.4 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 KFH42871.1 - 5e-47 159.8 0.1 1.2e-46 158.6 0.1 1.6 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.17 KFH42871.1 - 3e-37 127.0 0.1 2.3e-36 124.2 0.0 2.7 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 KFH42871.1 - 4.9e-36 124.1 0.7 1.7e-35 122.4 0.1 2.4 2 0 0 2 2 1 1 short chain dehydrogenase ADH_zinc_N PF00107.21 KFH42871.1 - 1.1e-18 67.0 0.0 3.4e-18 65.4 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFH42871.1 - 1e-08 36.1 0.0 4.8e-08 33.9 0.0 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFH42871.1 - 2.1e-06 27.4 0.2 4.8e-06 26.2 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 KFH42871.1 - 0.00046 20.3 0.8 0.0013 19.0 0.2 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KFH42871.1 - 0.0015 17.6 1.5 0.0029 16.6 0.2 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain DUF3898 PF13037.1 KFH42871.1 - 0.071 12.9 0.0 0.24 11.2 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3898) B12D PF06522.6 KFH42872.1 - 0.018 14.6 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit RRM_1 PF00076.17 KFH42873.1 - 2.8e-16 58.8 0.0 3.9e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH42873.1 - 1.3e-11 44.2 0.0 2.1e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH42873.1 - 4.2e-08 32.9 0.0 6.4e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ferric_reduct PF01794.14 KFH42874.1 - 1.8e-22 79.7 7.5 4.8e-22 78.3 5.2 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KFH42874.1 - 2.2e-18 66.6 0.0 1.8e-16 60.4 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KFH42874.1 - 2.2e-09 37.1 0.0 9.9e-08 31.8 0.0 2.4 1 1 0 1 1 1 1 FAD-binding domain IPK PF03770.11 KFH42875.1 - 2e-47 161.4 0.0 2.6e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase Ribonuclease_3 PF00636.21 KFH42876.1 - 2e-49 166.7 0.2 2.6e-24 85.8 0.0 3.8 4 0 0 4 4 4 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KFH42876.1 - 3.5e-30 104.6 0.0 1.3e-12 47.7 0.0 3.6 3 0 0 3 3 3 3 Ribonuclease-III-like Helicase_C PF00271.26 KFH42876.1 - 5.6e-16 58.1 0.1 1.4e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.9 KFH42876.1 - 1.7e-15 56.5 1.0 3.4e-14 52.3 0.0 3.1 3 0 0 3 3 3 1 Dicer dimerisation domain DEAD PF00270.24 KFH42876.1 - 2.4e-09 36.9 0.1 5.5e-09 35.7 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KFH42876.1 - 2.6e-08 33.9 1.4 1.4e-07 31.4 0.4 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KFH42876.1 - 0.0071 15.3 0.0 0.016 14.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) dsrm PF00035.20 KFH42876.1 - 0.089 13.3 0.6 25 5.5 0.0 3.0 3 0 0 3 3 3 0 Double-stranded RNA binding motif Synaptobrevin PF00957.16 KFH42877.1 - 2e-27 94.6 0.4 2.5e-27 94.3 0.3 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF1705 PF08019.7 KFH42877.1 - 0.1 12.0 0.2 0.13 11.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1705) DUF1100 PF06500.6 KFH42877.1 - 0.13 10.8 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_C12 PF01088.16 KFH42878.1 - 1.5e-57 194.2 0.0 5.6e-33 113.9 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 Fungal_trans PF04082.13 KFH42879.1 - 6.4e-19 67.8 0.0 1.1e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain NUDIX PF00293.23 KFH42881.1 - 9.2e-12 44.7 0.0 1.2e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Iso_dh PF00180.15 KFH42882.1 - 1.9e-65 221.1 0.0 2.8e-65 220.5 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase zf-MYND PF01753.13 KFH42883.1 - 0.34 10.8 5.2 0.73 9.7 3.6 1.6 1 0 0 1 1 1 0 MYND finger NmrA PF05368.8 KFH42884.1 - 4.3e-29 101.4 0.0 5.1e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFH42884.1 - 1.7e-18 67.2 0.0 4.2e-18 66.0 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 KFH42884.1 - 4.1e-06 26.4 0.0 1.4e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KFH42884.1 - 4.2e-05 23.5 0.2 8.9e-05 22.4 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH42884.1 - 0.011 15.4 0.1 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.14 KFH42884.1 - 0.045 12.4 0.0 0.075 11.7 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Rsm22 PF09243.5 KFH42885.1 - 1.1e-29 103.2 0.1 9.9e-29 100.2 0.1 2.4 2 1 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_18 PF12847.2 KFH42885.1 - 0.014 15.9 0.1 0.054 14.0 0.1 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KFH42885.1 - 0.022 15.1 0.0 0.066 13.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Phosphodiest PF01663.17 KFH42886.1 - 9.2e-87 291.7 0.7 1.2e-86 291.3 0.5 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KFH42886.1 - 0.0012 18.0 0.0 0.12 11.5 0.0 2.3 1 1 1 2 2 2 2 Sulfatase PglZ PF08665.7 KFH42886.1 - 0.052 13.2 0.9 0.3 10.7 0.1 2.4 3 0 0 3 3 3 0 PglZ domain DUF3904 PF13044.1 KFH42886.1 - 0.054 11.9 0.0 0.081 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3904) zf-MYND PF01753.13 KFH42887.1 - 1.9e-05 24.4 2.1 2.6e-05 23.9 1.4 1.2 1 0 0 1 1 1 1 MYND finger HAD PF12710.2 KFH42888.1 - 1.3e-17 64.5 0.1 1.8e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFH42888.1 - 4.5e-09 37.0 1.6 1.7e-07 31.8 1.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFH42888.1 - 8.4e-09 35.3 1.2 5.2e-08 32.7 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF705 PF05152.7 KFH42888.1 - 0.00022 20.3 0.1 0.00032 19.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF705) HAD_2 PF13419.1 KFH42888.1 - 0.011 15.9 0.0 0.036 14.3 0.0 1.8 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 KFH42888.1 - 0.13 11.3 0.1 7.8 5.5 0.0 2.1 2 0 0 2 2 2 0 Putative Phosphatase Methyltrn_RNA_3 PF02598.12 KFH42889.1 - 2.1e-86 289.9 0.0 2.4e-86 289.7 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase Lyase_1 PF00206.15 KFH42890.1 - 1.3e-19 70.5 0.1 2.4e-19 69.6 0.0 1.5 2 0 0 2 2 2 1 Lyase ADSL_C PF10397.4 KFH42890.1 - 7e-13 48.4 0.1 9.6e-12 44.7 0.0 2.6 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus TYW3 PF02676.9 KFH42891.1 - 1.1e-65 220.6 0.0 1.3e-65 220.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 DUF3353 PF11833.3 KFH42893.1 - 0.76 9.1 3.2 0.79 9.1 0.2 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3353) EMG1 PF03587.9 KFH42895.1 - 2.8e-77 258.5 0.0 3.4e-77 258.3 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase SRP14 PF02290.10 KFH42896.1 - 3.1e-23 81.4 0.0 4.9e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle 14kD protein Cys_Met_Meta_PP PF01053.15 KFH42897.1 - 1.9e-38 131.7 0.0 2.7e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme COQ9 PF08511.6 KFH42898.1 - 2.1e-31 107.2 0.0 3.1e-31 106.7 0.0 1.3 1 0 0 1 1 1 1 COQ9 DnaJ PF00226.26 KFH42899.1 - 6.8e-26 89.7 0.9 1.8e-25 88.4 0.6 1.8 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 KFH42899.1 - 2.1e-09 37.2 4.9 4.6e-09 36.1 0.6 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFH42899.1 - 2.2e-08 33.9 8.3 4.9e-08 32.9 1.5 2.8 2 1 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KFH42899.1 - 2e-07 31.0 6.8 0.0015 18.5 0.9 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 KFH42899.1 - 3.6e-06 26.9 5.2 0.023 15.0 0.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFH42899.1 - 0.00011 22.2 2.6 0.059 13.7 0.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFH42899.1 - 0.00027 20.7 1.1 0.41 10.6 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger RPT PF13446.1 KFH42899.1 - 0.011 15.0 0.1 0.035 13.5 0.0 1.8 1 1 0 1 1 1 0 A repeated domain in UCH-protein zf-H2C2_2 PF13465.1 KFH42899.1 - 0.13 12.6 0.8 2 8.8 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double domain C1_4 PF07975.7 KFH42899.1 - 0.47 10.5 3.2 14 5.8 0.4 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain DUF2387 PF09526.5 KFH42899.1 - 0.54 10.2 5.8 0.19 11.6 1.1 2.4 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) SGT1 PF07093.6 KFH42900.1 - 2.3e-140 468.8 31.2 6.1e-139 464.1 21.6 2.0 1 1 0 1 1 1 1 SGT1 protein Peptidase_C54 PF03416.14 KFH42901.1 - 8e-61 205.6 0.0 1.2e-60 205.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C54 AAA PF00004.24 KFH42902.1 - 1.9e-37 128.4 0.0 3.2e-37 127.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 KFH42902.1 - 6.3e-07 29.1 0.4 2.2e-05 24.2 0.0 3.5 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 KFH42902.1 - 1.4e-05 25.2 0.6 0.00019 21.6 0.1 2.8 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KFH42902.1 - 0.00011 21.4 0.0 0.00019 20.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 KFH42902.1 - 0.0015 17.3 0.0 0.0023 16.6 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 KFH42902.1 - 0.0021 17.8 0.0 0.0059 16.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KFH42902.1 - 0.0021 17.5 0.0 0.0041 16.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 KFH42902.1 - 0.0027 17.6 0.0 0.005 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KFH42902.1 - 0.0039 17.1 2.2 0.0072 16.3 0.1 2.5 3 2 0 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.16 KFH42902.1 - 0.0043 16.2 0.1 0.0084 15.2 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KFH42902.1 - 0.0062 16.2 0.2 0.027 14.2 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_11 PF13086.1 KFH42902.1 - 0.009 15.6 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFH42902.1 - 0.016 16.0 0.5 0.14 13.0 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KFH42902.1 - 0.017 15.0 0.0 0.037 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 KFH42902.1 - 0.024 13.5 0.0 0.042 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 KFH42902.1 - 0.034 13.5 0.0 0.2 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KFH42902.1 - 0.046 13.3 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KFH42902.1 - 0.076 12.9 1.4 0.22 11.4 0.0 2.3 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.1 KFH42902.1 - 0.092 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KFH42902.1 - 0.13 11.9 0.0 0.31 10.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain DUF927 PF06048.6 KFH42902.1 - 0.14 11.3 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF927) Sigma54_activat PF00158.21 KFH42902.1 - 0.15 11.5 0.0 0.32 10.4 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 KFH42902.1 - 0.16 11.2 0.0 0.32 10.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein EIID-AGA PF03613.9 KFH42902.1 - 0.2 10.5 0.1 0.31 9.9 0.1 1.1 1 0 0 1 1 1 0 PTS system mannose/fructose/sorbose family IID component APG9 PF04109.11 KFH42903.1 - 6.8e-153 508.9 2.1 9.2e-153 508.5 1.4 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 FA_desaturase PF00487.19 KFH42904.1 - 9.1e-38 130.1 23.8 1.4e-37 129.5 16.5 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KFH42904.1 - 6.4e-12 45.1 0.1 1.2e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain R3H PF01424.17 KFH42905.1 - 4.7e-13 48.6 0.0 1e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 KFH42905.1 - 4.8e-10 39.0 2.2 1.2e-09 37.7 1.6 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KFH42905.1 - 0.0013 18.5 1.1 0.0013 18.5 0.7 2.7 3 0 0 3 3 3 1 DExH-box splicing factor binding site MIF4G PF02854.14 KFH42906.1 - 2e-24 86.1 0.0 6.7e-24 84.4 0.0 1.8 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 KFH42906.1 - 3e-07 30.1 0.0 1.5e-06 27.8 0.0 2.3 1 1 0 1 1 1 1 MA3 domain Histone PF00125.19 KFH42907.1 - 7.6e-26 90.0 0.0 1.1e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFH42907.1 - 8.4e-06 25.7 0.0 1.7e-05 24.7 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Mito_carr PF00153.22 KFH42908.1 - 3.3e-60 199.8 9.7 1.8e-23 82.0 0.0 3.9 2 2 1 3 3 3 3 Mitochondrial carrier protein Dor1 PF04124.7 KFH42910.1 - 0.02 13.3 0.5 0.033 12.6 0.3 1.3 1 0 0 1 1 1 0 Dor1-like family YlqD PF11068.3 KFH42910.1 - 0.11 12.5 0.4 0.33 10.9 0.1 1.9 2 0 0 2 2 2 0 YlqD protein bZIP_2 PF07716.10 KFH42910.1 - 0.23 11.2 2.5 2.5 7.9 0.2 2.8 2 0 0 2 2 2 0 Basic region leucine zipper HlyD PF00529.15 KFH42910.1 - 3.6 6.8 9.7 4.8 6.3 2.2 2.1 2 0 0 2 2 2 0 HlyD family secretion protein Ribosomal_S17 PF00366.15 KFH42911.1 - 4.5e-05 23.4 1.4 0.0002 21.3 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein S17 GTP_EFTU_D2 PF03144.20 KFH42911.1 - 0.072 13.2 0.1 0.82 9.8 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu domain 2 RelB PF04221.7 KFH42911.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 RelB antitoxin Podoplanin PF05808.6 KFH42913.1 - 0.033 13.7 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Podoplanin RRM_1 PF00076.17 KFH42915.1 - 4.5e-35 119.1 0.0 9.1e-17 60.4 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH42915.1 - 6.6e-30 102.9 0.0 4.9e-15 55.2 0.0 2.5 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH42915.1 - 2.3e-16 59.3 0.0 3.4e-06 26.8 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP-grasp_2 PF08442.5 KFH42915.1 - 0.00056 19.3 0.0 0.11 11.8 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Limkain-b1 PF11608.3 KFH42915.1 - 0.026 14.2 0.0 1.7 8.4 0.0 3.2 2 2 0 2 2 2 0 Limkain b1 SPX PF03105.14 KFH42916.1 - 1.3e-38 133.3 0.1 2.1e-38 132.6 0.1 1.3 1 0 0 1 1 1 1 SPX domain zf-C3HC4_4 PF15227.1 KFH42916.1 - 4.9e-08 32.7 9.5 4.9e-08 32.7 6.6 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KFH42916.1 - 7.5e-08 31.9 10.4 1.6e-07 30.8 7.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFH42916.1 - 4.6e-07 29.7 11.8 9.5e-07 28.7 8.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFH42916.1 - 3.1e-06 26.7 8.8 6e-06 25.8 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFH42916.1 - 9.2e-06 25.2 9.7 1.9e-05 24.2 6.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KFH42916.1 - 1.1e-05 25.1 11.3 2.6e-05 23.9 7.8 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 KFH42916.1 - 0.00016 21.3 7.4 0.00049 19.7 5.1 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 KFH42916.1 - 0.00083 19.4 3.1 0.0017 18.4 2.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger TerY-C PF15616.1 KFH42916.1 - 0.0031 17.4 1.6 0.0061 16.4 1.1 1.5 1 0 0 1 1 1 1 TerY-C metal binding domain zf-RING_4 PF14570.1 KFH42916.1 - 0.0098 15.4 4.7 0.0098 15.4 3.2 1.8 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 KFH42916.1 - 0.012 15.3 2.8 0.031 14.0 2.0 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 KFH42916.1 - 0.031 14.1 1.6 0.06 13.1 1.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Histone_HNS PF00816.16 KFH42916.1 - 0.14 12.6 0.8 2.3 8.7 0.0 2.9 3 1 0 3 3 2 0 H-NS histone family DZR PF12773.2 KFH42916.1 - 5.3 6.9 6.0 20 5.0 4.3 1.9 1 1 1 2 2 2 0 Double zinc ribbon RRM_1 PF00076.17 KFH42917.1 - 1.5e-05 24.4 0.0 2.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH42917.1 - 0.0056 16.6 0.0 0.0093 15.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Apis_Csd PF11671.3 KFH42917.1 - 0.016 15.0 5.9 0.021 14.6 4.1 1.2 1 0 0 1 1 1 0 Complementary sex determiner protein Nha1_C PF08619.5 KFH42917.1 - 0.076 12.2 8.5 0.087 12.0 5.9 1.0 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus COG6 PF06419.6 KFH42919.1 - 2.4e-204 679.9 1.1 2.8e-204 679.8 0.8 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 RmuC PF02646.11 KFH42919.1 - 0.027 13.3 0.3 0.16 10.7 0.1 2.4 2 0 0 2 2 2 0 RmuC family COG2 PF06148.6 KFH42919.1 - 0.04 13.7 0.3 0.04 13.7 0.2 3.0 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 ArsC PF03960.10 KFH42919.1 - 0.12 12.5 0.8 3.7 7.6 0.1 2.8 2 0 0 2 2 2 0 ArsC family TPR_MLP1_2 PF07926.7 KFH42919.1 - 0.18 11.5 5.1 5 6.8 0.5 3.0 2 2 0 2 2 2 0 TPR/MLP1/MLP2-like protein Histone PF00125.19 KFH42920.1 - 9.3e-22 76.9 0.2 1.3e-21 76.4 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFH42920.1 - 3.8e-05 23.6 0.0 9.9e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KFH42920.1 - 0.00021 21.5 0.0 0.00036 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Mitofilin PF09731.4 KFH42920.1 - 0.0037 15.9 2.2 0.0046 15.6 1.5 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein RP-C PF03428.8 KFH42920.1 - 0.0088 15.5 0.1 0.012 15.0 0.1 1.2 1 0 0 1 1 1 1 Replication protein C N-terminal domain DUF1018 PF06252.7 KFH42920.1 - 0.022 15.2 0.6 0.03 14.8 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Pyr_redox_dim PF02852.17 KFH42921.1 - 1.2e-39 134.7 0.1 1.1e-38 131.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 KFH42921.1 - 1.4e-38 132.7 13.0 1e-27 97.3 1.0 4.4 2 1 2 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFH42921.1 - 1.4e-24 86.3 11.5 2.5e-21 75.8 0.7 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFH42921.1 - 8.8e-11 41.6 4.6 3.7e-06 26.8 0.5 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KFH42921.1 - 8.4e-10 38.2 9.9 2e-09 37.0 0.3 2.7 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFH42921.1 - 3.2e-09 36.1 12.6 5.7e-07 28.7 3.1 3.3 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.19 KFH42921.1 - 9.5e-08 31.3 19.1 0.00019 20.4 1.9 3.9 3 1 0 4 4 4 3 FAD dependent oxidoreductase GIDA PF01134.17 KFH42921.1 - 2.1e-07 30.1 14.4 4.2e-06 25.8 3.6 3.1 2 2 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 KFH42921.1 - 9.4e-07 28.1 4.6 1.9e-05 23.9 0.3 2.3 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.9 KFH42921.1 - 1.4e-06 27.0 15.3 8.6e-05 21.1 1.6 4.0 4 0 0 4 4 4 3 HI0933-like protein Pyr_redox_3 PF13738.1 KFH42921.1 - 1.8e-05 24.8 5.5 0.001 19.1 1.2 2.9 1 1 2 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KFH42921.1 - 2.3e-05 24.0 1.9 0.076 12.5 0.1 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 KFH42921.1 - 0.00046 20.3 2.0 0.3 11.3 0.3 3.0 2 1 0 2 2 2 2 Putative NAD(P)-binding FAD_binding_3 PF01494.14 KFH42921.1 - 0.0016 17.5 9.1 0.14 11.2 0.7 2.4 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KFH42921.1 - 0.0018 17.2 2.2 0.017 14.0 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein 3HCDH_N PF02737.13 KFH42921.1 - 0.03 13.9 0.4 0.03 13.9 0.3 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.1 KFH42921.1 - 0.083 13.2 0.0 6.1 7.1 0.0 3.1 3 1 0 3 3 3 0 XdhC Rossmann domain FMO-like PF00743.14 KFH42921.1 - 0.18 9.9 1.6 0.19 9.8 0.5 1.4 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like Trp_halogenase PF04820.9 KFH42921.1 - 1.7 7.2 9.3 0.087 11.4 0.8 2.1 2 0 0 2 2 2 0 Tryptophan halogenase DnaJ PF00226.26 KFH42922.1 - 1.6e-24 85.4 3.1 1.6e-24 85.4 2.2 2.3 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.1 KFH42922.1 - 4e-23 80.8 5.9 6.3e-10 38.5 0.0 5.2 3 2 1 5 5 5 4 TPR repeat TPR_16 PF13432.1 KFH42922.1 - 2.1e-19 69.6 2.6 3.7e-05 24.2 0.0 5.5 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.23 KFH42922.1 - 8.4e-19 66.3 0.8 0.00014 21.2 0.0 5.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 KFH42922.1 - 8.2e-18 62.8 8.7 0.0015 18.2 0.1 7.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.1 KFH42922.1 - 7.7e-17 60.9 0.3 1.9e-05 24.4 0.0 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFH42922.1 - 2.2e-14 52.6 10.4 0.027 15.1 0.0 7.9 3 3 5 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFH42922.1 - 1.2e-13 49.7 0.4 0.011 15.4 0.1 6.1 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFH42922.1 - 2.5e-11 42.8 5.5 0.0098 16.0 0.0 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat Apc3 PF12895.2 KFH42922.1 - 5.5e-07 29.6 2.1 0.13 12.4 0.0 4.3 3 2 3 6 6 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KFH42922.1 - 2.9e-06 27.5 11.8 0.018 15.3 0.3 4.9 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 KFH42922.1 - 3.7e-06 27.0 8.0 3.5 8.2 0.0 6.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFH42922.1 - 3.7e-06 26.7 10.1 0.27 11.1 0.1 5.3 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFH42922.1 - 5.1e-06 25.8 5.7 0.13 12.1 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat DUF1217 PF06748.7 KFH42922.1 - 0.0026 17.8 0.4 0.015 15.4 0.3 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1217) PPTA PF01239.17 KFH42922.1 - 0.017 14.4 0.1 1.2 8.5 0.0 2.5 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat BTAD PF03704.12 KFH42922.1 - 0.21 11.9 8.0 41 4.4 0.9 4.4 2 1 3 5 5 5 0 Bacterial transcriptional activator domain TPR_4 PF07721.9 KFH42922.1 - 0.42 11.1 9.1 16 6.3 2.7 3.6 3 0 0 3 3 2 0 Tetratricopeptide repeat THUMP PF02926.12 KFH42923.1 - 3.3e-07 30.2 0.3 0.00033 20.5 0.1 2.3 2 0 0 2 2 2 2 THUMP domain Crust_neurohorm PF01147.12 KFH42924.1 - 0.024 13.9 3.0 0.042 13.1 2.1 1.4 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family Cas_Cas4 PF01930.12 KFH42924.1 - 0.065 13.1 1.8 0.097 12.5 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF83 Crisp PF08562.5 KFH42924.1 - 0.19 12.0 6.4 0.28 11.5 4.5 1.3 1 0 0 1 1 1 0 Crisp NDT80_PhoG PF05224.7 KFH42925.1 - 1.9e-41 142.0 0.0 2.9e-41 141.5 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family TSC21 PF15217.1 KFH42925.1 - 0.058 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 TSC21 family NMO PF03060.10 KFH42927.1 - 1.9e-73 247.5 0.2 2.3e-73 247.2 0.2 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KFH42927.1 - 6.8e-08 31.7 0.0 1.7e-06 27.1 0.0 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KFH42927.1 - 2.5e-05 23.2 3.4 4.2e-05 22.5 2.3 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 KFH42927.1 - 0.0039 16.1 0.2 0.0061 15.5 0.1 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.12 KFH42927.1 - 0.075 11.9 0.2 0.12 11.2 0.1 1.4 1 0 0 1 1 1 0 Conserved region in glutamate synthase NanE PF04131.9 KFH42927.1 - 0.076 11.9 0.1 0.21 10.5 0.1 1.7 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Abhydrolase_6 PF12697.2 KFH42929.1 - 5.6e-29 101.6 0.2 2.3e-28 99.6 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFH42929.1 - 3.4e-16 59.4 0.0 2.1e-15 56.8 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFH42929.1 - 4.8e-12 45.8 0.0 1.2e-10 41.2 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 KFH42929.1 - 0.0001 21.9 0.0 0.0002 21.0 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.15 KFH42929.1 - 0.00012 21.6 0.0 0.00023 20.6 0.0 1.5 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.6 KFH42929.1 - 0.00016 20.8 0.0 0.00047 19.3 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_3 PF07859.8 KFH42929.1 - 0.017 14.7 0.0 0.052 13.1 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KFH42929.1 - 0.019 14.4 0.0 4.4 6.6 0.0 2.5 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Thioesterase PF00975.15 KFH42929.1 - 0.032 14.4 0.1 0.099 12.8 0.1 2.0 1 1 0 1 1 1 0 Thioesterase domain Hydrolase_4 PF12146.3 KFH42929.1 - 0.043 13.6 0.0 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 Putative lysophospholipase PGAP1 PF07819.8 KFH42929.1 - 0.078 12.5 0.0 0.67 9.4 0.0 2.0 2 0 0 2 2 2 0 PGAP1-like protein DUF2305 PF10230.4 KFH42929.1 - 0.14 11.5 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Chlorophyllase2 PF12740.2 KFH42929.1 - 0.16 10.8 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme DAGK_cat PF00781.19 KFH42930.1 - 3.8e-07 29.5 0.0 8.5e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain eIF3g PF12353.3 KFH42933.1 - 2.4e-46 156.7 6.0 3.8e-46 156.1 4.1 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 KFH42933.1 - 2.3e-16 59.1 0.1 5.5e-16 57.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH42933.1 - 2.9e-12 46.3 0.1 5.3e-12 45.5 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH42933.1 - 7e-08 32.2 0.1 1.3e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Trypan_PARP PF05887.6 KFH42934.1 - 0.0013 18.5 4.5 0.0025 17.6 3.1 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Pol_alpha_B_N PF08418.5 KFH42934.1 - 2.4 7.6 6.0 3.3 7.1 4.2 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF3435 PF11917.3 KFH42935.1 - 1.6e-07 30.4 0.1 4.3e-06 25.7 0.0 1.9 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) TRM PF02005.11 KFH42936.1 - 3.2e-102 342.2 0.0 1.1e-91 307.5 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_26 PF13659.1 KFH42936.1 - 3.6e-05 23.7 0.1 9e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFH42936.1 - 0.013 14.9 0.0 0.049 12.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain zf-ribbon_3 PF13248.1 KFH42936.1 - 0.013 14.7 0.5 0.03 13.5 0.3 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zf-NADH-PPase PF09297.6 KFH42936.1 - 0.017 14.6 0.9 0.046 13.2 0.6 1.8 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.1 KFH42936.1 - 0.064 12.7 0.8 0.16 11.5 0.6 1.6 1 0 0 1 1 1 0 zinc-ribbon domain UPF0547 PF10571.4 KFH42936.1 - 0.14 11.9 1.0 0.28 10.9 0.7 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 TIM21 PF08294.6 KFH42937.1 - 6.3e-38 129.6 0.1 5.2e-36 123.4 0.0 2.1 1 1 0 1 1 1 1 TIM21 Coa1 PF08695.5 KFH42937.1 - 1.9e-05 24.1 0.0 4.3e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF2178 PF09946.4 KFH42937.1 - 0.065 12.9 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) zf-H2C2_2 PF13465.1 KFH42939.1 - 4.5e-10 39.3 16.5 3.7e-06 26.9 2.4 3.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFH42939.1 - 2.2e-07 30.8 13.6 0.0025 18.0 1.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFH42939.1 - 3.1e-06 27.1 12.7 0.0057 16.9 0.9 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger DUF2225 PF09986.4 KFH42939.1 - 0.42 10.0 0.9 0.88 8.9 0.6 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF676 PF05057.9 KFH42940.1 - 3.4e-43 147.4 0.0 5e-28 97.8 0.0 3.2 3 0 0 3 3 3 3 Putative serine esterase (DUF676) BSP_II PF05432.6 KFH42940.1 - 0.0014 17.9 3.0 0.0035 16.6 2.1 1.6 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) PGAP1 PF07819.8 KFH42940.1 - 0.036 13.6 0.1 0.063 12.8 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein CDC45 PF02724.9 KFH42940.1 - 0.43 8.5 6.2 0.7 7.8 4.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DTHCT PF08070.6 KFH42940.1 - 0.77 10.4 13.7 0.029 14.9 4.1 2.8 2 0 0 2 2 2 0 DTHCT (NUC029) region Lactonase PF10282.4 KFH42942.1 - 1.1e-82 277.9 0.0 1.3e-82 277.7 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller NUDIX_4 PF14815.1 KFH42942.1 - 0.2 11.1 0.0 0.45 9.9 0.0 1.6 1 0 0 1 1 1 0 NUDIX domain Pterin_bind PF00809.17 KFH42943.1 - 6.4e-65 218.4 0.0 1e-64 217.7 0.0 1.4 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 KFH42943.1 - 1.2e-41 141.3 0.0 2.2e-41 140.5 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) SPR1 PF15356.1 KFH42944.1 - 0.057 13.7 2.9 0.065 13.5 2.0 1.1 1 0 0 1 1 1 0 Psoriasis susceptibility locus 2 Ribosomal_L7Ae PF01248.21 KFH42945.1 - 3.2e-22 77.8 0.1 3.7e-22 77.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KFH42945.1 - 0.0049 16.7 0.0 0.0058 16.4 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 ArfGap PF01412.13 KFH42946.1 - 2.1e-36 124.2 0.4 3.7e-36 123.4 0.3 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF3275 PF11679.3 KFH42946.1 - 0.14 11.7 0.1 0.14 11.7 0.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3275) Pkinase PF00069.20 KFH42947.1 - 1.7e-31 109.3 0.0 6.8e-31 107.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH42947.1 - 3.9e-13 49.0 0.0 3.6e-05 22.9 0.0 3.1 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 KFH42947.1 - 0.0024 17.6 0.1 0.019 14.7 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KFH42947.1 - 0.0029 16.6 0.1 0.17 10.8 0.0 2.8 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.9 KFH42947.1 - 0.025 13.6 0.0 0.051 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC_tran PF00005.22 KFH42948.1 - 8.1e-45 152.4 3.4 1.2e-21 77.4 0.0 3.7 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 KFH42948.1 - 5.4e-15 56.1 3.6 0.00066 19.7 0.0 4.3 4 0 0 4 4 4 4 AAA domain ABC_tran_2 PF12848.2 KFH42948.1 - 1.3e-09 37.7 3.2 3.7e-09 36.2 2.2 1.8 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 KFH42948.1 - 2.6e-08 33.2 0.3 0.00021 20.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 KFH42948.1 - 4.1e-08 32.7 0.1 0.033 13.4 0.0 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KFH42948.1 - 6.3e-08 33.4 0.1 0.005 17.6 0.0 3.1 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KFH42948.1 - 5.9e-07 29.4 0.0 0.043 13.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 KFH42948.1 - 2.1e-06 27.9 0.5 0.22 11.6 0.0 3.7 3 1 0 3 3 3 2 AAA domain DUF258 PF03193.11 KFH42948.1 - 5e-06 25.7 0.1 0.048 12.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 KFH42948.1 - 5.2e-06 26.9 0.1 0.054 14.0 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein Dynamin_N PF00350.18 KFH42948.1 - 9.7e-06 25.4 0.6 0.048 13.4 0.0 3.1 4 0 0 4 4 3 2 Dynamin family AAA_16 PF13191.1 KFH42948.1 - 1.1e-05 25.5 4.3 0.063 13.2 0.1 3.2 3 0 0 3 3 3 2 AAA ATPase domain ArgK PF03308.11 KFH42948.1 - 1.3e-05 24.1 1.2 0.0075 15.0 0.0 2.3 2 0 0 2 2 2 2 ArgK protein AAA_28 PF13521.1 KFH42948.1 - 1.4e-05 25.1 0.3 0.0093 15.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KFH42948.1 - 1.9e-05 24.9 0.2 0.09 13.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KFH42948.1 - 5.6e-05 23.5 7.9 0.035 14.4 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_30 PF13604.1 KFH42948.1 - 6.7e-05 22.5 0.4 0.11 12.0 0.0 3.5 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.1 KFH42948.1 - 7.5e-05 22.6 0.0 0.5 10.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 KFH42948.1 - 0.00013 21.6 0.2 0.19 11.4 0.0 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 KFH42948.1 - 0.00038 20.6 0.1 0.063 13.4 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KFH42948.1 - 0.00042 19.9 0.1 0.058 13.0 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_15 PF13175.1 KFH42948.1 - 0.00044 19.4 0.0 0.2 10.6 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_10 PF12846.2 KFH42948.1 - 0.00078 18.9 0.3 0.88 8.9 0.1 2.5 2 0 0 2 2 2 2 AAA-like domain AAA_25 PF13481.1 KFH42948.1 - 0.00086 18.7 0.1 0.045 13.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 KFH42948.1 - 0.00092 19.0 5.4 0.22 11.3 0.0 3.1 4 0 0 4 4 3 2 Domain of unknown function DUF87 ATP-synt_ab PF00006.20 KFH42948.1 - 0.0017 17.8 0.0 1.9 7.9 0.0 2.3 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.8 KFH42948.1 - 0.003 16.5 0.2 0.44 9.4 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Thymidylate_kin PF02223.12 KFH42948.1 - 0.0058 16.0 0.4 0.91 8.8 0.0 2.6 2 0 0 2 2 2 1 Thymidylate kinase AAA_14 PF13173.1 KFH42948.1 - 0.0059 16.5 0.3 5.2 6.9 0.0 3.4 4 0 0 4 4 3 0 AAA domain Arf PF00025.16 KFH42948.1 - 0.0071 15.6 0.6 0.32 10.2 0.1 2.8 3 0 0 3 3 3 1 ADP-ribosylation factor family RNA_helicase PF00910.17 KFH42948.1 - 0.0075 16.4 0.1 0.78 9.9 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_13 PF13166.1 KFH42948.1 - 0.008 14.7 4.0 1.6 7.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 KFH42948.1 - 0.0086 15.8 0.4 2.1 8.0 0.0 2.6 2 0 0 2 2 2 1 Archaeal ATPase NB-ARC PF00931.17 KFH42948.1 - 0.039 12.8 1.9 0.81 8.4 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain NTPase_1 PF03266.10 KFH42948.1 - 0.041 13.5 2.4 1.8 8.2 0.0 2.7 3 0 0 3 3 2 0 NTPase cobW PF02492.14 KFH42948.1 - 0.043 13.2 0.7 6.1 6.2 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 KFH42948.1 - 0.05 13.3 0.4 0.54 10.0 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain AAA_5 PF07728.9 KFH42948.1 - 0.072 12.8 0.5 1.1 9.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.13 KFH42948.1 - 0.17 11.3 0.1 6.2 6.2 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ABC_ATPase PF09818.4 KFH42948.1 - 0.49 8.9 3.1 0.4 9.2 0.0 2.3 3 0 0 3 3 3 0 Predicted ATPase of the ABC class FtsK_SpoIIIE PF01580.13 KFH42948.1 - 2 7.8 5.9 1.5 8.2 0.1 3.1 4 0 0 4 4 3 0 FtsK/SpoIIIE family Spo7 PF03907.8 KFH42949.1 - 5.1e-67 225.5 0.0 7.1e-67 225.0 0.0 1.1 1 0 0 1 1 1 1 Spo7-like protein Macoilin PF09726.4 KFH42949.1 - 2.5 6.2 10.9 3.4 5.8 7.5 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF221 PF02714.10 KFH42950.1 - 9.4e-96 320.4 23.7 9.4e-96 320.4 16.4 2.1 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KFH42950.1 - 3.5e-40 137.1 2.4 3.5e-40 137.1 1.7 3.2 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KFH42950.1 - 9.3e-18 63.9 0.0 2.6e-17 62.4 0.0 1.8 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 KFH42950.1 - 7.3e-15 55.2 1.5 4.9e-06 26.9 0.7 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4463) DUF3040 PF11239.3 KFH42950.1 - 0.36 10.9 0.0 0.36 10.9 0.0 4.2 4 1 0 4 4 4 0 Protein of unknown function (DUF3040) DUF912 PF06024.7 KFH42950.1 - 0.94 9.5 11.8 2.5 8.1 0.0 4.6 4 0 0 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4501 PF14946.1 KFH42950.1 - 1.8 8.0 2.7 16 4.9 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4501) Bromodomain PF00439.20 KFH42951.1 - 6e-18 64.5 0.0 1.1e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Bromodomain BTB PF00651.26 KFH42951.1 - 1.9e-06 27.8 0.0 3.3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain CYSTM PF12734.2 KFH42952.1 - 0.99 9.5 47.6 1.5e+04 -4.0 33.0 4.3 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance Glyco_trans_1_2 PF13524.1 KFH42954.1 - 0.37 11.0 2.1 3.6 7.9 0.1 2.1 2 0 0 2 2 2 0 Glycosyl transferases group 1 DUF4398 PF14346.1 KFH42954.1 - 1.7 8.7 14.9 5.2 7.1 10.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4398) MARVEL PF01284.18 KFH42955.1 - 1.5e-06 28.1 11.2 1.5e-05 24.8 7.1 2.0 1 1 1 2 2 2 1 Membrane-associating domain Yip1 PF04893.12 KFH42955.1 - 0.0015 18.0 4.7 0.0021 17.5 3.3 1.1 1 0 0 1 1 1 1 Yip1 domain BMC PF00936.14 KFH42955.1 - 0.081 12.6 0.1 0.54 9.9 0.0 2.3 3 0 0 3 3 3 0 BMC domain DUF4234 PF14018.1 KFH42955.1 - 0.21 11.3 1.4 0.86 9.3 0.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) Pkinase PF00069.20 KFH42956.1 - 8.1e-30 103.8 0.0 4.3e-29 101.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH42956.1 - 3.9e-09 35.9 0.0 6e-05 22.2 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase DnaB_C PF03796.10 KFH42957.1 - 0.002 17.0 0.5 0.024 13.5 0.1 2.5 3 0 0 3 3 3 1 DnaB-like helicase C terminal domain Rad51 PF08423.6 KFH42957.1 - 0.0023 16.9 0.1 0.015 14.1 0.0 2.2 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KFH42957.1 - 0.0082 15.5 0.2 0.047 13.0 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KFH42957.1 - 0.011 15.9 0.0 0.028 14.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFH42957.1 - 0.02 15.0 0.0 0.064 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 KFH42957.1 - 0.036 13.1 0.9 0.045 12.8 0.1 1.5 2 0 0 2 2 2 0 KaiC AAA_11 PF13086.1 KFH42957.1 - 0.06 12.9 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFH42957.1 - 0.091 12.6 0.5 0.45 10.3 0.4 2.3 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KFH42957.1 - 0.13 11.9 0.7 0.37 10.5 0.5 1.8 1 1 0 1 1 1 0 Part of AAA domain Fringe PF02434.11 KFH42959.1 - 0.003 16.8 0.0 0.0056 15.9 0.0 1.4 1 0 0 1 1 1 1 Fringe-like Zn_clus PF00172.13 KFH42960.1 - 1.6e-09 37.5 8.4 1.6e-09 37.5 5.8 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFH42960.1 - 1.9e-07 30.2 0.1 3.2e-07 29.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PEMT PF04191.8 KFH42962.1 - 1.1e-56 189.4 8.7 1.4e-34 118.3 0.7 2.8 2 0 0 2 2 2 2 Phospholipid methyltransferase TBCA PF02970.11 KFH42963.1 - 1.4e-17 63.5 5.6 1.9e-17 63.0 3.7 1.3 1 1 0 1 1 1 1 Tubulin binding cofactor A Syntaxin PF00804.20 KFH42963.1 - 0.012 15.7 0.7 0.019 15.1 0.4 1.4 1 1 1 2 2 2 0 Syntaxin RRF_GI PF12614.3 KFH42963.1 - 0.021 14.6 0.6 0.024 14.4 0.4 1.1 1 0 0 1 1 1 0 Ribosome recycling factor Far-17a_AIG1 PF04750.9 KFH42964.1 - 6.3e-55 185.4 16.6 7.2e-55 185.2 11.5 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Claudin_2 PF13903.1 KFH42964.1 - 2.7 7.6 9.3 8.7 6.0 3.4 2.3 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Hexokinase_2 PF03727.11 KFH42965.1 - 1.9e-88 295.7 0.0 2.9e-88 295.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KFH42965.1 - 2.3e-75 252.4 0.0 1.2e-74 250.1 0.0 1.9 2 0 0 2 2 2 1 Hexokinase WD40 PF00400.27 KFH42968.1 - 4.9e-07 29.3 0.1 0.22 11.4 0.0 4.2 5 0 0 5 5 5 2 WD domain, G-beta repeat PD40 PF07676.7 KFH42968.1 - 0.0026 17.3 0.1 0.05 13.2 0.0 2.8 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat SR-25 PF10500.4 KFH42968.1 - 0.026 13.9 2.6 0.046 13.1 1.8 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.8 KFH42968.1 - 0.38 8.5 3.4 0.6 7.9 2.4 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein MCM PF00493.18 KFH42970.1 - 4.9e-138 459.4 0.0 6.8e-138 458.9 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KFH42970.1 - 2.5e-25 89.3 0.3 8.4e-25 87.6 0.2 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KFH42970.1 - 1.9e-05 23.8 0.0 0.00045 19.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KFH42970.1 - 3.2e-05 23.6 0.0 0.00013 21.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KFH42970.1 - 0.0032 17.0 0.0 0.011 15.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2201_N PF13203.1 KFH42971.1 - 7.5 5.6 5.6 11 5.0 3.9 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain CarboxypepD_reg PF13620.1 KFH42972.1 - 0.24 11.4 7.9 17 5.5 4.3 3.1 3 1 0 3 3 3 0 Carboxypeptidase regulatory-like domain Daxx PF03344.10 KFH42972.1 - 0.84 8.0 9.6 1.1 7.6 6.7 1.1 1 0 0 1 1 1 0 Daxx Family FGF-BP1 PF06473.7 KFH42972.1 - 0.87 9.1 9.4 1.2 8.6 6.5 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) NOA36 PF06524.7 KFH42972.1 - 1.2 8.3 5.6 1.5 8.0 3.9 1.1 1 0 0 1 1 1 0 NOA36 protein Mucin PF01456.12 KFH42972.1 - 2.6 7.8 38.0 2.8 7.6 25.8 1.5 1 1 0 1 1 1 0 Mucin-like glycoprotein CENP-B_dimeris PF09026.5 KFH42972.1 - 2.7 8.2 6.6 0.51 10.5 1.7 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain MRI PF15325.1 KFH42972.1 - 4.2 8.3 10.7 7 7.6 7.4 1.4 1 0 0 1 1 1 0 Modulator of retrovirus infection Macoilin PF09726.4 KFH42972.1 - 7.3 4.7 5.7 8.5 4.5 4.0 1.0 1 0 0 1 1 1 0 Transmembrane protein UPF0560 PF10577.4 KFH42972.1 - 9.2 4.3 10.0 11 4.0 6.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Dicty_REP PF05086.7 KFH42972.1 - 9.8 3.7 14.8 12 3.5 10.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein VTC PF09359.5 KFH42973.1 - 4.1e-101 337.7 0.1 6.5e-101 337.0 0.0 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 KFH42973.1 - 2.8e-27 96.2 1.7 4.3e-12 46.3 0.0 3.8 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 KFH42973.1 - 5e-11 42.6 1.1 5e-11 42.6 0.7 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Fe_dep_repress PF01325.14 KFH42973.1 - 0.0025 17.6 0.1 0.0051 16.7 0.1 1.5 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain TrmB PF01978.14 KFH42973.1 - 0.0026 17.4 0.1 0.01 15.5 0.1 2.0 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_29 PF13551.1 KFH42973.1 - 0.04 14.0 0.1 0.58 10.3 0.0 2.7 3 0 0 3 3 3 0 Winged helix-turn helix PBP1_TM PF14812.1 KFH42974.1 - 0.73 10.1 5.6 0.93 9.8 3.9 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Leo1 PF04004.8 KFH42975.1 - 5.9e-30 104.2 0.0 1.1e-29 103.3 0.0 1.4 1 0 0 1 1 1 1 Leo1-like protein DUF3042 PF11240.3 KFH42975.1 - 0.014 15.1 2.1 0.04 13.7 1.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Sua5_yciO_yrdC PF01300.13 KFH42976.1 - 2.2e-51 173.6 0.0 3.1e-51 173.1 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 KFH42976.1 - 1.9e-24 86.1 0.0 5.9e-24 84.5 0.0 1.9 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding F-box PF00646.28 KFH42978.1 - 0.00011 21.7 0.1 0.0002 20.8 0.1 1.4 1 0 0 1 1 1 1 F-box domain Aldedh PF00171.17 KFH42979.1 - 2.5e-133 444.7 0.1 3.4e-133 444.3 0.1 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KFH42979.1 - 0.093 11.4 0.0 0.16 10.6 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) MF_alpha_N PF05436.6 KFH42980.1 - 0.079 12.6 0.1 0.079 12.6 0.1 1.9 2 0 0 2 2 2 0 Mating factor alpha precursor N-terminus Apt1 PF10351.4 KFH42980.1 - 0.76 8.5 5.6 0.93 8.2 3.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Nop14 PF04147.7 KFH42980.1 - 2 6.2 14.3 2.1 6.1 9.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KFH42980.1 - 7.1 4.5 12.6 8 4.3 8.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.4 KFH42980.1 - 8.2 4.5 9.4 8.9 4.4 6.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Rad21_Rec8_N PF04825.8 KFH42981.1 - 1.6e-37 127.7 0.3 4.4e-37 126.4 0.0 1.9 2 0 0 2 2 2 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 KFH42981.1 - 1.2e-08 33.9 0.2 3.2e-08 32.6 0.1 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 KFH42981.1 - 0.049 13.2 1.2 0.078 12.5 0.0 1.9 3 0 0 3 3 3 0 ScpA/B protein Aldolase_II PF00596.16 KFH42982.1 - 3.8e-40 137.4 0.0 4.7e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain zf-H2C2_2 PF13465.1 KFH42983.1 - 3.8e-06 26.9 12.7 4.9e-06 26.5 0.9 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 KFH42983.1 - 6.1e-05 23.1 0.5 6.1e-05 23.1 0.4 3.4 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFH42983.1 - 0.00024 21.2 0.4 0.00024 21.2 0.3 2.8 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFH42983.1 - 0.33 11.1 5.5 1.3 9.2 0.5 2.8 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding COG4 PF08318.7 KFH42984.1 - 1.2e-94 316.7 0.0 1.7e-94 316.2 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein DUF294_C PF10335.4 KFH42984.1 - 0.12 12.0 0.7 0.28 10.8 0.5 1.6 1 0 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain MRP_L53 PF10780.4 KFH42985.1 - 1.1e-19 70.0 0.5 1.5e-19 69.6 0.3 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Sel1 PF08238.7 KFH42986.1 - 1.2e-16 60.7 14.6 4.6e-06 27.0 1.9 3.7 3 0 0 3 3 3 3 Sel1 repeat YppG PF14179.1 KFH42986.1 - 1.4 9.5 25.8 3.2 8.3 17.9 1.6 1 0 0 1 1 1 0 YppG-like protein Pil1 PF13805.1 KFH42987.1 - 3.1e-105 351.1 0.3 4.2e-105 350.7 0.2 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 DUF2508 PF10704.4 KFH42987.1 - 0.0017 18.4 0.9 0.031 14.4 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2508) Ank_2 PF12796.2 KFH42988.1 - 0.00013 22.2 0.0 0.0014 18.9 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFH42988.1 - 0.066 13.4 0.2 0.69 10.2 0.1 2.7 2 1 1 3 3 3 0 Ankyrin repeats (many copies) THOC7 PF05615.8 KFH42989.1 - 8.6e-35 120.0 4.5 8.6e-35 120.0 3.1 2.0 1 1 1 2 2 2 1 Tho complex subunit 7 FUSC PF04632.7 KFH42989.1 - 0.07 11.5 7.4 0.088 11.2 5.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family RTBV_P46 PF06216.6 KFH42989.1 - 0.49 9.1 6.9 0.15 10.8 1.9 1.8 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein Atg14 PF10186.4 KFH42989.1 - 7.4 5.4 13.5 0.77 8.6 4.6 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Pro_isomerase PF00160.16 KFH42990.1 - 9.8e-51 172.0 0.1 2.1e-50 170.9 0.1 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 KFH42990.1 - 5.7e-16 57.7 0.2 1.9e-07 30.6 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Ribophorin_I PF04597.9 KFH42991.1 - 3.2e-144 480.6 0.0 3.7e-144 480.4 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I Sld5 PF05916.6 KFH42992.1 - 3.5e-08 33.6 0.1 6.2e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 GINS complex protein DUF896 PF05979.7 KFH42992.1 - 0.047 13.2 0.2 0.11 12.1 0.0 1.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF896) Clat_adaptor_s PF01217.15 KFH42994.1 - 5.4e-17 61.8 0.8 5.3e-16 58.6 0.5 1.9 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Cys_Met_Meta_PP PF01053.15 KFH42996.1 - 2.1e-30 105.3 0.0 2.7e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KFH42996.1 - 4.5e-10 39.0 0.0 6.9e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Indigoidine_A PF04227.7 KFH42997.1 - 1.2e-103 346.3 0.5 1.7e-103 345.8 0.4 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 KFH42997.1 - 1.4e-19 70.3 0.0 2e-17 63.3 0.0 2.8 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Mob1_phocein PF03637.12 KFH42998.1 - 1.2e-30 106.4 2.1 3.2e-16 59.4 0.3 2.4 2 1 0 2 2 2 2 Mob1/phocein family DUF3336 PF11815.3 KFH42999.1 - 1e-37 128.8 1.0 4.4e-37 126.8 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KFH42999.1 - 7e-15 55.4 0.8 2.4e-14 53.7 0.1 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase NDUF_C2 PF06374.6 KFH43000.1 - 0.21 11.5 0.6 0.74 9.8 0.1 2.0 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) bZIP_1 PF00170.16 KFH43001.1 - 7.6e-09 35.4 13.6 1.4e-08 34.5 8.7 2.0 1 1 1 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.12 KFH43001.1 - 9.9e-06 25.7 12.8 2.8e-05 24.3 8.9 1.8 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.10 KFH43001.1 - 1.1e-05 25.1 13.5 3.2e-05 23.6 9.4 1.9 1 0 0 1 1 1 1 Basic region leucine zipper DUF342 PF03961.8 KFH43001.1 - 0.028 12.8 5.2 0.039 12.3 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) HeLo PF14479.1 KFH43001.1 - 0.035 13.8 7.3 0.058 13.1 5.0 1.3 1 0 0 1 1 1 0 Prion-inhibition and propagation DUF2968 PF11180.3 KFH43001.1 - 0.19 11.0 10.9 0.37 10.1 7.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) APG6 PF04111.7 KFH43001.1 - 3.5 6.5 12.4 6.1 5.7 8.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 KFH43001.1 - 6.6 6.2 12.6 13 5.3 8.7 1.5 1 0 0 1 1 1 0 IncA protein adh_short PF00106.20 KFH43002.1 - 1.8e-27 96.2 3.7 4.2e-27 95.1 2.5 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH43002.1 - 1.2e-12 48.1 0.0 1.6e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH43002.1 - 2.4e-09 37.0 6.1 3e-08 33.5 4.2 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KFH43002.1 - 2.5e-07 30.3 0.9 4.1e-07 29.6 0.1 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFH43002.1 - 1.6e-05 24.9 0.1 2.5e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KFH43002.1 - 0.00047 18.9 0.3 0.00066 18.4 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KFH43002.1 - 0.0015 17.4 0.1 0.0023 16.8 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 2-Hacid_dh_C PF02826.14 KFH43002.1 - 0.019 14.0 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Urocanase PF01175.13 KFH43002.1 - 0.028 12.4 0.0 0.047 11.7 0.0 1.3 1 0 0 1 1 1 0 Urocanase AlaDh_PNT_C PF01262.16 KFH43002.1 - 0.073 12.6 0.4 0.13 11.8 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PALP PF00291.20 KFH43002.1 - 0.095 11.9 0.1 0.92 8.6 0.0 2.0 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme ApbA PF02558.11 KFH43002.1 - 0.11 11.9 0.3 1 8.7 0.2 2.4 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Calreticulin PF00262.13 KFH43003.1 - 2.4e-161 536.4 21.2 3.6e-161 535.8 14.7 1.2 1 0 0 1 1 1 1 Calreticulin family OAD_gamma PF04277.8 KFH43003.1 - 0.24 11.7 4.3 0.16 12.3 0.3 2.7 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain E1-E2_ATPase PF00122.15 KFH43004.1 - 2.4e-72 242.7 0.0 4.1e-72 241.9 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFH43004.1 - 1.3e-42 145.4 1.5 2.5e-42 144.4 1.0 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFH43004.1 - 2.5e-29 103.2 0.0 2.1e-28 100.2 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFH43004.1 - 5.7e-19 67.3 0.0 1.1e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KFH43004.1 - 1.4e-14 54.7 0.0 2.9e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFH43004.1 - 2.4e-13 49.8 0.0 4.7e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFH43004.1 - 1.3e-05 24.9 1.1 0.00024 20.7 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Transport_MerF PF11431.3 KFH43004.1 - 0.075 12.6 2.8 2.2 7.9 0.2 2.6 2 0 0 2 2 2 0 Membrane transport protein MerF VWA_2 PF13519.1 KFH43004.1 - 0.079 13.0 3.5 0.27 11.3 0.0 3.1 3 1 0 3 3 3 0 von Willebrand factor type A domain adh_short PF00106.20 KFH43005.1 - 3.1e-25 89.0 0.3 4.2e-25 88.5 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH43005.1 - 3.5e-13 49.5 0.3 4.4e-13 49.2 0.2 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFH43005.1 - 2.5e-09 37.2 0.0 3.2e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF4439 PF14530.1 KFH43005.1 - 0.0038 17.7 0.1 0.0085 16.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4439) NmrA PF05368.8 KFH43005.1 - 0.061 12.5 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family DUF1776 PF08643.5 KFH43005.1 - 0.11 11.6 0.0 5.3 6.0 0.0 2.1 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Semialdhyde_dh PF01118.19 KFH43005.1 - 0.11 12.7 0.1 0.28 11.4 0.0 1.8 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Tannase PF07519.6 KFH43006.1 - 5e-101 338.7 1.2 6.2e-101 338.4 0.8 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 KFH43006.1 - 1.3e-08 34.6 0.0 7.4e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFH43006.1 - 6e-06 26.2 0.0 4.2e-05 23.5 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFH43006.1 - 0.0011 18.2 0.1 0.53 9.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KFH43006.1 - 0.0021 17.6 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Sec20 PF03908.8 KFH43007.1 - 3.5e-15 55.4 1.9 4.7e-15 55.0 0.3 1.9 2 0 0 2 2 2 1 Sec20 WXG100 PF06013.7 KFH43007.1 - 0.39 10.7 3.8 2.2 8.3 0.6 2.6 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DUF848 PF05852.6 KFH43007.1 - 1.2 9.0 6.6 0.5 10.2 0.1 2.8 2 1 0 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) T2SF PF00482.18 KFH43007.1 - 2.1 8.2 6.6 0.52 10.2 0.4 2.6 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F PEP-utilisers_N PF05524.8 KFH43007.1 - 3.4 7.4 9.2 4.1 7.2 1.2 3.1 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal DAHP_synth_1 PF00793.15 KFH43008.1 - 2e-98 328.4 0.1 2.3e-98 328.1 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family zf-CCCH PF00642.19 KFH43009.1 - 4.4e-12 45.3 30.2 1.2e-06 28.0 0.8 5.3 4 1 1 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pyrophosphatase PF00719.14 KFH43010.1 - 3.7e-52 175.9 0.1 4.7e-52 175.5 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase DUF2531 PF10748.4 KFH43010.1 - 0.13 11.5 0.0 17 4.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2531) p450 PF00067.17 KFH43011.1 - 1.8e-67 227.8 0.0 2.3e-67 227.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SLAIN PF15301.1 KFH43012.1 - 0.031 13.4 6.6 0.05 12.7 4.6 1.3 1 0 0 1 1 1 0 SLAIN motif-containing family Mucin PF01456.12 KFH43012.1 - 1.7 8.3 34.6 0.2 11.4 20.6 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein Med3 PF11593.3 KFH43012.1 - 4.3 6.4 15.1 5.9 6.0 10.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal M_domain PF12938.2 KFH43012.1 - 7.3 6.3 6.7 22 4.7 4.7 1.7 1 1 0 1 1 1 0 M domain of GW182 Mannitol_dh_C PF08125.8 KFH43014.1 - 1.1e-46 159.0 0.0 1.5e-46 158.5 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 KFH43014.1 - 1.9e-18 66.8 0.1 8e-18 64.8 0.0 1.9 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain UDPG_MGDP_dh_N PF03721.9 KFH43014.1 - 0.0027 17.1 1.1 0.012 15.0 0.1 2.3 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HPIP PF15226.1 KFH43015.1 - 0.098 12.7 0.4 0.16 12.0 0.2 1.4 1 1 0 1 1 1 0 HCF-1 beta-propeller-interacting protein family Pkinase_C PF00433.19 KFH43017.1 - 1.1e-12 48.2 1.0 3.3e-12 46.7 0.7 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Pkinase PF00069.20 KFH43018.1 - 2.8e-06 26.6 0.0 0.045 12.8 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain DUF221 PF02714.10 KFH43020.1 - 2.8e-104 348.5 25.9 6.6e-104 347.2 17.9 1.7 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KFH43020.1 - 8e-43 145.7 3.9 8e-43 145.7 2.7 3.7 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KFH43020.1 - 1.8e-32 111.1 0.2 3.8e-32 110.0 0.1 1.6 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 KFH43020.1 - 5.7e-21 74.8 0.6 8.9e-21 74.2 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) p450 PF00067.17 KFH43021.1 - 1.4e-60 205.1 0.0 1.8e-60 204.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Proteasome PF00227.21 KFH43023.1 - 3e-42 144.0 0.0 3.4e-42 143.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit PIRT PF15099.1 KFH43024.1 - 0.00066 18.9 0.0 0.0016 17.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family SKG6 PF08693.5 KFH43024.1 - 0.003 16.8 1.1 0.0073 15.6 0.8 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Herpes_gE PF02480.11 KFH43024.1 - 0.015 13.5 0.0 0.03 12.5 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Mito_fiss_reg PF05308.6 KFH43024.1 - 0.075 12.3 2.4 0.21 10.9 1.6 1.7 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF4381 PF14316.1 KFH43024.1 - 0.088 12.9 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DNA_pol_viral_N PF00242.12 KFH43024.1 - 5.4 5.9 6.9 0.17 10.8 0.3 1.7 2 0 0 2 2 2 0 DNA polymerase (viral) N-terminal domain adh_short PF00106.20 KFH43025.1 - 1.8e-26 93.0 4.7 2.4e-26 92.6 3.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH43025.1 - 5.5e-14 52.5 0.7 7.3e-14 52.1 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH43025.1 - 5.2e-08 32.7 2.9 8.1e-08 32.1 2.0 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KFH43025.1 - 0.017 14.7 0.5 0.033 13.8 0.4 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 KFH43025.1 - 0.12 12.4 0.6 0.37 10.8 0.3 2.0 1 1 1 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_10 PF13460.1 KFH43025.1 - 0.12 12.3 5.2 2.6 8.0 2.2 2.5 2 1 0 2 2 2 0 NADH(P)-binding Epimerase PF01370.16 KFH43025.1 - 0.21 11.0 1.2 0.54 9.6 0.8 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family WSC PF01822.14 KFH43026.1 - 1.2e-11 44.3 7.4 2.8e-11 43.2 5.1 1.6 1 0 0 1 1 1 1 WSC domain Podoplanin PF05808.6 KFH43026.1 - 0.0015 18.1 2.8 0.0027 17.2 1.9 1.4 1 0 0 1 1 1 1 Podoplanin P12 PF12669.2 KFH43026.1 - 0.02 15.0 0.1 0.077 13.2 0.1 2.0 1 0 0 1 1 1 0 Virus attachment protein p12 family SKG6 PF08693.5 KFH43026.1 - 0.044 13.1 5.8 0.12 11.6 4.0 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3042 PF11240.3 KFH43026.1 - 0.36 10.6 1.9 0.95 9.3 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Tyrosinase PF00264.15 KFH43027.1 - 2e-36 126.2 0.7 3.1e-36 125.6 0.5 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Abhydrolase_1 PF00561.15 KFH43028.1 - 1.1e-42 146.1 0.1 1.7e-41 142.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KFH43028.1 - 1.3e-13 51.3 1.4 7.2e-13 48.9 0.9 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH43028.1 - 0.00012 21.8 0.0 0.2 11.4 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KFH43028.1 - 0.051 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Arf PF00025.16 KFH43029.1 - 1.8e-42 144.5 0.0 2e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFH43029.1 - 2.2e-18 66.1 0.0 2.6e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFH43029.1 - 3.1e-10 40.5 0.0 2.1e-09 37.8 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 KFH43029.1 - 3.7e-07 29.5 0.0 4.6e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KFH43029.1 - 5.2e-06 25.4 0.1 7.7e-06 24.8 0.1 1.5 1 1 0 1 1 1 1 G-protein alpha subunit SRPRB PF09439.5 KFH43029.1 - 1e-05 24.8 0.0 1.2e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KFH43029.1 - 8e-05 22.5 0.0 0.00013 21.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFH43029.1 - 8.2e-05 22.1 0.0 0.00066 19.1 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KFH43029.1 - 0.0096 15.7 0.0 0.1 12.4 0.1 2.0 1 1 1 2 2 2 1 Dynamin family ATP_bind_1 PF03029.12 KFH43029.1 - 0.058 12.9 0.0 0.083 12.4 0.0 1.4 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein FeoB_N PF02421.13 KFH43029.1 - 0.065 12.5 0.7 0.18 11.1 0.5 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA PF00004.24 KFH43029.1 - 0.1 12.7 0.0 0.69 10.1 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 KFH43029.1 - 0.16 11.4 0.2 0.58 9.6 0.0 1.9 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MFS_1 PF07690.11 KFH43031.1 - 3.9e-13 48.8 47.9 2.6e-12 46.1 33.0 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Fst_toxin PF13955.1 KFH43031.1 - 0.8 9.4 8.9 0.47 10.1 1.6 3.2 2 0 0 2 2 2 0 Toxin Fst, type I toxin-antitoxin system Transferase PF02458.10 KFH43032.1 - 2.3e-27 95.5 0.0 1.8e-18 66.2 0.0 2.7 2 1 0 2 2 2 2 Transferase family Coatomer_WDAD PF04053.9 KFH43033.1 - 3.1e-172 573.3 0.0 5.4e-172 572.5 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 KFH43033.1 - 1.3e-47 158.0 11.8 2.6e-10 39.7 0.2 8.3 9 0 0 9 9 9 6 WD domain, G-beta repeat Nup160 PF11715.3 KFH43033.1 - 4.9e-05 21.6 4.4 0.026 12.6 2.6 4.2 1 1 1 2 2 2 1 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 KFH43033.1 - 0.0059 16.3 0.0 1.5 8.5 0.0 3.3 2 1 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Peripla_BP_6 PF13458.1 KFH43033.1 - 0.044 13.1 0.0 0.084 12.2 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein CBP PF12192.3 KFH43034.1 - 0.0059 16.5 2.0 0.0059 16.5 1.4 2.8 2 1 1 3 3 3 1 Fungal calcium binding protein Radical_SAM PF04055.16 KFH43035.1 - 1.1e-10 41.8 0.0 1.8e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 KFH43035.1 - 7.1e-06 26.1 0.0 1.2e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 KFH43035.1 - 0.0013 18.7 0.1 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain PGI PF00342.14 KFH43036.1 - 3.8e-208 691.8 0.1 4.3e-208 691.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase FTA2 PF13095.1 KFH43037.1 - 2.6e-27 95.8 0.0 3.4e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Aldedh PF00171.17 KFH43038.1 - 3.8e-145 483.7 0.0 4.3e-145 483.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Evr1_Alr PF04777.8 KFH43039.1 - 3e-27 94.3 0.0 4.3e-27 93.8 0.0 1.2 1 0 0 1 1 1 1 Erv1 / Alr family Prenyltrans_1 PF13243.1 KFH43040.1 - 5.8e-29 100.2 0.0 3.7e-10 39.7 0.0 6.2 4 2 2 6 6 6 5 Prenyltransferase-like Prenyltrans_2 PF13249.1 KFH43040.1 - 1.8e-28 99.1 1.1 1.2e-13 51.5 0.1 5.3 3 2 2 6 6 6 5 Prenyltransferase-like Prenyltrans PF00432.16 KFH43040.1 - 1.6e-24 85.1 5.8 7.7e-06 25.3 0.0 6.4 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.5 KFH43040.1 - 9.9e-07 28.2 0.2 0.012 14.7 0.0 4.4 5 1 1 6 6 6 2 Pectic acid lyase A2M_comp PF07678.9 KFH43040.1 - 0.00078 18.7 0.0 0.087 12.0 0.0 3.1 3 1 1 4 4 4 1 A-macroglobulin complement component Lipase_GDSL_2 PF13472.1 KFH43041.1 - 0.031 14.3 0.0 0.031 14.3 0.0 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family PI-PLC-X PF00388.14 KFH43042.1 - 1.1e-11 44.3 0.0 1.7e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain p450 PF00067.17 KFH43043.1 - 5.3e-68 229.6 0.0 6.5e-68 229.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tho2 PF11262.3 KFH43044.1 - 8.2e-73 245.0 0.0 1.3e-72 244.3 0.0 1.4 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 KFH43044.1 - 2.8e-26 91.0 0.1 5.9e-26 90.0 0.1 1.6 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Cyclin PF08613.6 KFH43045.1 - 3e-38 131.5 1.4 1.1e-22 81.0 0.1 2.5 2 0 0 2 2 2 2 Cyclin Sugar_tr PF00083.19 KFH43046.1 - 4.2e-48 164.0 0.3 7.6e-48 163.2 0.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH43046.1 - 2.1e-23 82.6 24.3 2.1e-23 82.6 16.8 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 KFH43046.1 - 5.1e-05 21.8 7.0 5.1e-05 21.8 4.9 2.5 2 1 1 3 3 3 1 MFS/sugar transport protein Usher PF00577.15 KFH43046.1 - 0.11 11.2 0.1 0.19 10.3 0.1 1.3 1 0 0 1 1 1 0 Outer membrane usher protein RNA_pol_Rpb2_6 PF00562.23 KFH43047.1 - 1.8e-114 382.5 0.0 2.3e-114 382.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KFH43047.1 - 7e-31 106.7 0.0 1.1e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KFH43047.1 - 1.6e-24 86.3 0.0 2.6e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 KFH43047.1 - 3.5e-24 84.3 0.0 1.2e-23 82.6 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 KFH43047.1 - 4.7e-23 80.8 0.0 1.1e-22 79.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 KFH43047.1 - 3.7e-15 55.9 0.0 1.9e-14 53.6 0.0 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 KFH43047.1 - 0.0034 17.3 0.0 0.0074 16.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Aldo_ket_red PF00248.16 KFH43048.1 - 2.5e-45 154.4 0.0 3e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family XH PF03469.9 KFH43048.1 - 0.056 13.1 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 XH domain CCDC144C PF14915.1 KFH43048.1 - 0.073 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Polysacc_deac_1 PF01522.16 KFH43049.1 - 7.9e-32 109.4 0.0 1.3e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 KFH43049.1 - 4e-07 29.8 14.0 7.2e-07 29.0 9.7 1.4 1 0 0 1 1 1 1 Chitin recognition protein Glyco_hydro_57 PF03065.10 KFH43049.1 - 0.061 12.2 0.0 0.084 11.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 CPSF_A PF03178.10 KFH43050.1 - 4e-62 210.1 0.0 6.7e-62 209.4 0.0 1.4 1 0 0 1 1 1 1 CPSF A subunit region Kinesin PF00225.18 KFH43051.1 - 5.3e-116 386.9 0.0 7.4e-116 386.5 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Herpes_UL14 PF03580.9 KFH43051.1 - 0.00074 19.3 2.4 0.0021 17.8 1.6 1.8 1 0 0 1 1 1 1 Herpesvirus UL14-like protein AAA_33 PF13671.1 KFH43051.1 - 0.023 14.5 0.1 0.13 12.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain adh_short_C2 PF13561.1 KFH43052.1 - 1.8e-30 106.4 0.3 2.1e-30 106.2 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFH43052.1 - 1.8e-26 93.0 0.7 2.3e-26 92.7 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH43052.1 - 1.6e-13 50.7 0.3 2.1e-13 50.3 0.2 1.1 1 0 0 1 1 1 1 KR domain ERO1 PF04137.10 KFH43053.1 - 4.2e-133 443.7 0.0 5.2e-133 443.4 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) HVSL PF09749.4 KFH43054.1 - 5.1e-66 222.1 0.0 6.1e-66 221.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein Mac PF12464.3 KFH43054.1 - 0.034 14.1 0.0 2.3 8.3 0.0 2.5 2 0 0 2 2 2 0 Maltose acetyltransferase ER_lumen_recept PF00810.13 KFH43056.1 - 4.8e-37 127.6 4.7 7.6e-37 127.0 3.3 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 KFH43056.1 - 0.4 10.2 0.0 0.4 10.2 0.0 3.2 3 1 0 3 3 3 0 PQ loop repeat IDO PF01231.13 KFH43057.1 - 1.2e-139 465.3 0.0 1.4e-139 465.1 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF605 PF04652.11 KFH43059.1 - 2.3e-92 310.3 20.0 2.6e-92 310.1 13.8 1.0 1 0 0 1 1 1 1 Vta1 like PAT1 PF09770.4 KFH43059.1 - 3.2 5.8 30.8 4.5 5.3 21.4 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ADK PF00406.17 KFH43060.1 - 5e-35 120.6 0.0 3.3e-20 72.4 0.1 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 KFH43060.1 - 9.4e-12 44.3 0.0 1.7e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 KFH43060.1 - 0.0011 19.7 0.0 0.0018 19.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFH43060.1 - 0.0016 18.7 0.1 0.012 15.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KFH43060.1 - 0.05 13.3 0.0 0.098 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KFH43060.1 - 0.063 13.1 0.1 0.37 10.6 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.1 KFH43060.1 - 0.11 12.5 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Metallophos PF00149.23 KFH43061.1 - 2.9e-10 39.8 3.0 2.7e-09 36.6 2.1 2.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Na_Ca_ex PF01699.19 KFH43061.1 - 0.14 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Sodium/calcium exchanger protein ADH_N PF08240.7 KFH43063.1 - 6.7e-29 99.8 0.7 6.7e-29 99.8 0.5 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFH43063.1 - 3.6e-19 68.5 0.2 5.3e-19 68.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFH43063.1 - 0.0016 19.3 0.0 0.0028 18.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 KFH43063.1 - 0.044 13.3 0.3 0.063 12.8 0.2 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase CGI-121 PF08617.5 KFH43064.1 - 1.6e-47 161.1 0.0 1.8e-47 161.0 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 DUF4149 PF13664.1 KFH43065.1 - 3.2e-21 75.2 2.2 3.3e-21 75.2 0.9 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) MFS_1 PF07690.11 KFH43067.1 - 1.2e-37 129.4 55.8 4e-36 124.4 34.8 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH43067.1 - 1.3e-05 23.9 7.5 1.3e-05 23.9 5.2 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter zf-C2H2 PF00096.21 KFH43069.1 - 3e-06 27.2 3.3 0.016 15.4 0.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFH43069.1 - 0.00017 21.6 1.9 0.038 14.3 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFH43069.1 - 0.0034 17.4 1.6 2 8.6 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFH43069.1 - 0.088 12.7 3.0 3 7.8 0.0 2.6 1 1 1 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.7 KFH43069.1 - 0.13 12.3 1.8 2.6 8.2 0.6 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 KFH43069.1 - 0.16 12.1 1.6 2.7 8.1 0.2 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Aminotran_5 PF00266.14 KFH43070.1 - 1e-08 34.3 0.0 3.2e-08 32.7 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KFH43070.1 - 0.044 12.8 0.0 0.079 11.9 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family NmrA PF05368.8 KFH43071.1 - 8.5e-34 116.8 0.0 1.4e-33 116.1 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFH43071.1 - 3.8e-12 46.6 0.0 5.7e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KFH43071.1 - 0.00067 19.6 0.4 0.0017 18.2 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase TrkA_N PF02254.13 KFH43071.1 - 0.0008 19.3 0.0 0.0018 18.2 0.0 1.6 2 0 0 2 2 2 1 TrkA-N domain Epimerase PF01370.16 KFH43071.1 - 0.001 18.5 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 KFH43071.1 - 0.0036 17.6 0.0 0.0083 16.5 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 KFH43071.1 - 0.0069 16.6 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 KFH43071.1 - 0.091 11.6 0.1 0.14 11.0 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain AA_permease PF00324.16 KFH43072.1 - 1.6e-119 399.3 27.2 1.8e-119 399.2 18.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFH43072.1 - 1.5e-33 116.0 33.4 1.7e-33 115.8 23.2 1.0 1 0 0 1 1 1 1 Amino acid permease Cellulase PF00150.13 KFH43073.1 - 4.7e-19 68.6 4.2 6.5e-19 68.1 2.9 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) LMBR1 PF04791.11 KFH43074.1 - 1.1e-13 50.5 14.6 1.1e-11 43.9 10.1 2.6 1 1 0 1 1 1 1 LMBR1-like membrane protein UPF0233 PF06781.7 KFH43074.1 - 0.091 12.3 0.1 0.091 12.3 0.1 3.2 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0233) 60KD_IMP PF02096.15 KFH43074.1 - 0.98 9.0 7.1 0.24 11.0 0.5 2.8 2 1 0 2 2 2 0 60Kd inner membrane protein Pal1 PF08316.6 KFH43075.1 - 9.7e-07 29.3 0.0 2.4e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Pal1 cell morphology protein CKS PF01111.14 KFH43076.1 - 3.5e-33 113.2 0.6 4.3e-33 112.9 0.4 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit HsbA PF12296.3 KFH43078.1 - 1.4e-20 73.3 5.0 2.3e-20 72.6 3.5 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A DUF1069 PF06370.6 KFH43078.1 - 0.06 12.7 0.2 0.095 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1069) Seryl_tRNA_N PF02403.17 KFH43078.1 - 0.082 12.9 0.0 0.19 11.7 0.0 1.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Epimerase PF01370.16 KFH43080.1 - 8e-17 61.4 0.0 1.1e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFH43080.1 - 3e-15 55.6 0.0 6.8e-15 54.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KFH43080.1 - 3.5e-11 42.4 0.0 6.4e-07 28.5 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 KFH43080.1 - 4.4e-10 39.8 0.2 9.1e-10 38.8 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KFH43080.1 - 7.5e-08 32.4 0.1 1.7e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 KFH43080.1 - 3e-06 26.6 0.1 4.4e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 KFH43080.1 - 0.00019 20.4 0.0 0.00033 19.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 KFH43080.1 - 0.01 15.4 1.5 0.18 11.4 1.1 2.5 1 1 0 1 1 1 0 KR domain RmlD_sub_bind PF04321.12 KFH43080.1 - 0.023 13.6 0.1 0.1 11.4 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain UCR_TM PF02921.9 KFH43080.1 - 0.13 12.4 0.5 0.82 9.9 0.1 2.1 2 0 0 2 2 2 0 Ubiquinol cytochrome reductase transmembrane region LETM1 PF07766.8 KFH43081.1 - 2.9e-107 357.6 1.6 6.1e-107 356.6 1.1 1.5 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.22 KFH43081.1 - 6.2e-06 25.5 0.5 0.0024 17.3 0.0 4.0 4 0 0 4 4 4 1 SAP domain Thioredoxin PF00085.15 KFH43082.1 - 4.1e-32 109.9 0.0 5.8e-26 90.1 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 KFH43082.1 - 2.6e-09 37.1 0.0 1.9e-08 34.3 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KFH43082.1 - 3.1e-06 27.3 3.5 0.0018 18.4 0.0 3.3 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KFH43082.1 - 9.9e-05 22.3 0.0 0.024 14.7 0.0 3.5 3 2 1 4 4 4 1 Thioredoxin-like Thioredoxin_7 PF13899.1 KFH43082.1 - 0.0067 16.4 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.1 KFH43082.1 - 0.81 9.1 0.0 0.81 9.1 0.0 3.6 4 0 0 4 4 4 0 F plasmid transfer operon protein FMN_bind_2 PF04299.7 KFH43083.1 - 3.7e-51 172.9 0.0 4.4e-51 172.7 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain NIF PF03031.13 KFH43084.1 - 5.4e-36 123.6 0.0 8.2e-36 123.0 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Pribosyltran_N PF13793.1 KFH43084.1 - 0.054 13.2 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of ribose phosphate pyrophosphokinase SOG2 PF10428.4 KFH43084.1 - 0.25 9.9 3.3 0.38 9.3 2.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein COX6A PF02046.10 KFH43085.1 - 1.1e-43 147.8 4.0 1.1e-43 147.7 2.8 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa RNase_PH PF01138.16 KFH43086.1 - 1.7e-34 118.9 0.1 3.3e-34 118.0 0.1 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Pro_dh PF01619.13 KFH43087.1 - 3.2e-38 131.4 0.0 5e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 Proline dehydrogenase Sporozoite_P67 PF05642.6 KFH43087.1 - 3.9 5.2 6.1 6.2 4.5 4.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.12 KFH43087.1 - 9.5 5.9 21.2 1.5 8.6 11.6 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein FAD_binding_4 PF01565.18 KFH43088.1 - 5.1e-21 74.6 0.1 9.3e-21 73.7 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain DUF2824 PF11039.3 KFH43088.1 - 0.11 12.2 0.1 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2824) DUF221 PF02714.10 KFH43090.1 - 1.3e-102 342.9 12.0 2.3e-102 342.2 8.3 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KFH43090.1 - 3.2e-37 127.5 2.0 4.3e-37 127.0 0.1 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KFH43090.1 - 4.5e-22 77.7 0.1 1.3e-21 76.3 0.0 1.8 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 KFH43090.1 - 8.2e-07 29.4 1.5 6.5e-06 26.5 1.1 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 KFH43090.1 - 0.035 14.0 0.0 0.085 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFH43090.1 - 0.038 13.6 0.0 0.095 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH43090.1 - 0.095 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans PF04082.13 KFH43091.1 - 2.8e-17 62.4 0.0 7.8e-17 61.0 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH43091.1 - 0.0014 18.5 1.8 0.0014 18.5 1.3 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OPT PF03169.10 KFH43092.1 - 9.2e-85 285.3 44.1 1.2e-84 284.9 30.6 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3093 PF11292.3 KFH43092.1 - 0.09 12.5 1.6 0.37 10.5 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) DUF3425 PF11905.3 KFH43094.1 - 1.2e-16 60.8 0.0 2.5e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) RNA_pol_Rpc4 PF05132.9 KFH43094.1 - 0.14 12.1 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Abi PF02517.11 KFH43095.1 - 3.7e-12 46.2 11.7 3.7e-12 46.2 8.1 2.4 1 1 1 2 2 2 1 CAAX protease self-immunity Sad1_UNC PF07738.8 KFH43096.1 - 7.7e-38 129.3 0.0 1.2e-37 128.6 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal F5_F8_type_C PF00754.20 KFH43096.1 - 0.019 14.7 0.0 0.053 13.3 0.0 1.7 1 0 0 1 1 1 0 F5/8 type C domain Sec1 PF00995.18 KFH43097.1 - 1.1e-154 516.2 0.0 1.3e-154 516.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family CDP-OH_P_transf PF01066.16 KFH43098.1 - 6.4e-17 61.7 5.7 6.4e-17 61.7 4.0 1.6 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Aa_trans PF01490.13 KFH43099.1 - 1.1e-63 215.1 25.9 1.5e-63 214.7 18.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Fcf2 PF08698.6 KFH43100.1 - 1.2e-24 86.1 0.2 2e-24 85.4 0.1 1.4 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing Sec15 PF04091.7 KFH43101.1 - 5.8e-111 370.7 6.5 6.2e-111 370.6 2.3 2.3 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like DUF4201 PF13870.1 KFH43101.1 - 0.00036 19.9 4.4 0.00044 19.7 1.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) Baculo_PEP_C PF04513.7 KFH43101.1 - 4.4 7.1 13.1 3.6 7.4 1.0 3.4 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Peptidase_M24 PF00557.19 KFH43102.1 - 1.6e-38 132.3 0.1 3.1e-37 128.1 0.1 2.3 1 1 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KFH43102.1 - 2.4e-22 79.8 0.0 9.5e-18 64.9 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain tRNA-synt_1b PF00579.20 KFH43103.1 - 1.3e-72 244.3 0.0 1.8e-72 243.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) HTH_Tnp_1 PF01527.15 KFH43103.1 - 0.083 12.8 0.1 2.5 8.1 0.0 3.1 3 0 0 3 3 3 0 Transposase DUF3321 PF11968.3 KFH43104.1 - 5.4e-85 284.4 0.0 7.1e-85 284.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 KFH43104.1 - 0.00033 20.4 0.0 0.00053 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF434 PF04256.7 KFH43104.1 - 0.0062 15.8 0.4 0.012 14.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF434) DER1 PF04511.10 KFH43105.1 - 1.8e-49 167.9 4.7 2.1e-49 167.7 3.2 1.0 1 0 0 1 1 1 1 Der1-like family Serpentine_r_xa PF03383.10 KFH43105.1 - 0.42 10.3 2.6 0.56 9.9 1.5 1.3 1 1 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa SPC12 PF06645.8 KFH43106.1 - 5e-26 90.3 0.0 5.4e-26 90.2 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF4440 PF14534.1 KFH43107.1 - 4.3e-09 36.5 0.0 5.4e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) DUF1856 PF08983.5 KFH43107.1 - 0.027 14.5 0.5 0.07 13.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1856) zf-Tim10_DDP PF02953.10 KFH43108.1 - 4.9e-21 73.7 5.1 5.9e-21 73.5 3.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Mu-like_Pro PF10123.4 KFH43108.1 - 0.05 13.0 0.1 0.05 13.0 0.0 1.0 1 0 0 1 1 1 0 Mu-like prophage I protein Spore_III_AB PF09548.5 KFH43108.1 - 0.091 12.5 0.1 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) PNRC PF15365.1 KFH43109.1 - 1.4e-07 31.3 13.6 0.00022 21.1 5.9 4.3 3 1 0 3 3 3 2 Proline-rich nuclear receptor coactivator DUF2015 PF09435.5 KFH43110.1 - 5.2e-46 155.5 0.0 5.8e-46 155.4 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) ARD PF03079.9 KFH43111.1 - 1.2e-46 158.4 0.1 1.5e-46 158.1 0.1 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 KFH43111.1 - 2.8e-08 33.1 0.1 4.5e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 KFH43111.1 - 6.3e-06 25.9 0.0 9.1e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 KFH43111.1 - 0.016 14.6 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Cupin WD40 PF00400.27 KFH43112.1 - 3.6e-70 229.5 14.3 1.2e-10 40.8 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 KFH43112.1 - 3.4e-21 75.1 7.5 6e-21 74.4 5.2 1.4 1 0 0 1 1 1 1 Tup N-terminal Nup160 PF11715.3 KFH43112.1 - 0.001 17.3 0.2 0.19 9.8 0.0 3.2 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFH43112.1 - 0.015 14.0 0.1 0.58 8.8 0.0 3.0 1 1 2 3 3 3 0 Nup133 N terminal like Cytochrom_D1 PF02239.11 KFH43112.1 - 0.053 11.8 0.1 1.6 6.9 0.1 2.6 2 1 1 3 3 3 0 Cytochrome D1 heme domain Nbas_N PF15492.1 KFH43112.1 - 0.054 12.5 0.0 4.8 6.2 0.0 2.9 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal LXG PF04740.7 KFH43112.1 - 0.069 12.9 0.4 0.1 12.3 0.3 1.2 1 0 0 1 1 1 0 LXG domain of WXG superfamily Macoilin PF09726.4 KFH43112.1 - 0.28 9.4 0.5 0.42 8.8 0.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Pkinase PF00069.20 KFH43113.1 - 3.9e-59 199.9 0.0 6.5e-59 199.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH43113.1 - 1.4e-34 119.3 0.0 2.1e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH43113.1 - 7.2e-16 57.9 0.0 6.3e-13 48.3 0.0 2.6 1 1 2 3 3 3 2 Kinase-like Kdo PF06293.9 KFH43113.1 - 0.0057 15.7 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family UAA PF08449.6 KFH43114.1 - 6.4e-11 41.7 12.3 6.4e-11 41.7 8.6 1.5 1 1 1 2 2 2 1 UAA transporter family TPT PF03151.11 KFH43114.1 - 1.3e-09 37.9 5.9 1.3e-09 37.9 4.1 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KFH43114.1 - 0.0023 17.9 4.9 0.0023 17.9 3.4 2.5 2 1 0 2 2 2 1 EamA-like transporter family Ldh_1_N PF00056.18 KFH43115.1 - 1.9e-42 144.4 0.1 2.8e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KFH43115.1 - 3.4e-42 144.1 0.0 5.4e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 KFH43115.1 - 0.00078 18.2 0.0 0.0011 17.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KFH43115.1 - 0.034 14.4 0.0 0.085 13.1 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 KFH43115.1 - 0.087 11.8 0.0 0.43 9.6 0.0 2.0 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF2404 PF10296.4 KFH43116.1 - 3.9e-08 33.3 0.0 7.1e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) GIDA PF01134.17 KFH43117.1 - 5.1e-155 516.1 0.0 6.3e-155 515.8 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 KFH43117.1 - 1.1e-16 60.5 0.1 2.9e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 GidA associated domain 3 FAD_oxidored PF12831.2 KFH43117.1 - 1.5e-07 30.8 0.0 2.8e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFH43117.1 - 4.8e-07 29.8 0.1 1.2e-06 28.5 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFH43117.1 - 0.00083 18.3 1.5 0.00083 18.3 1.1 1.8 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.16 KFH43117.1 - 0.002 17.7 0.1 0.0037 16.8 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.19 KFH43117.1 - 0.005 15.8 1.3 0.18 10.6 0.6 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KFH43117.1 - 0.0069 14.9 1.3 0.088 11.2 0.5 2.3 2 0 0 2 2 2 1 HI0933-like protein PA_decarbox PF05870.6 KFH43117.1 - 0.059 12.8 0.1 7.1 6.0 0.1 2.9 3 0 0 3 3 3 0 Phenolic acid decarboxylase (PAD) NAD_binding_7 PF13241.1 KFH43117.1 - 0.06 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.1 KFH43117.1 - 0.063 13.3 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFH43117.1 - 0.11 12.8 0.3 0.26 11.7 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFH43117.1 - 0.14 11.8 0.7 0.35 10.6 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding DJ-1_PfpI PF01965.19 KFH43117.1 - 0.16 11.3 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family K_oxygenase PF13434.1 KFH43117.1 - 0.17 10.7 0.0 0.33 9.8 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Tyr-DNA_phospho PF06087.7 KFH43118.1 - 4.6e-72 243.0 0.0 5.4e-72 242.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 KFH43118.1 - 5.3e-05 22.9 0.0 0.0038 16.9 0.0 2.8 2 1 0 2 2 2 1 PLD-like domain UIM PF02809.15 KFH43118.1 - 0.0055 16.1 0.9 0.0055 16.1 0.6 2.2 2 0 0 2 2 2 1 Ubiquitin interaction motif CBFD_NFYB_HMF PF00808.18 KFH43120.1 - 1.3e-19 69.9 0.6 1.9e-19 69.4 0.4 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFH43120.1 - 2.2e-12 46.9 0.1 3.3e-12 46.3 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 KFH43120.1 - 0.02 14.6 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Xpo1 PF08389.7 KFH43122.1 - 7e-08 32.4 0.0 7.4e-05 22.7 0.0 2.8 2 0 0 2 2 2 2 Exportin 1-like protein Ribosomal_L23eN PF03939.8 KFH43123.1 - 4.2e-19 68.3 14.8 4.2e-19 68.3 10.3 2.9 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 KFH43123.1 - 2.5e-17 62.5 0.8 5.6e-17 61.4 0.5 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 Med3 PF11593.3 KFH43123.1 - 0.016 14.4 0.2 0.017 14.3 0.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ribosomal_S10 PF00338.17 KFH43124.1 - 1.2e-23 82.7 0.0 1.8e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e HAD_2 PF13419.1 KFH43125.1 - 1e-32 113.7 0.0 1.2e-32 113.5 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 KFH43125.1 - 0.029 14.5 0.0 0.038 14.1 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase zf-rbx1 PF12678.2 KFH43126.1 - 5.6e-35 119.2 13.5 6.7e-35 119.0 9.3 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KFH43126.1 - 2.6e-17 62.4 9.8 3.3e-17 62.1 6.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KFH43126.1 - 6.2e-07 29.1 11.4 4e-06 26.5 7.9 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KFH43126.1 - 0.0012 18.4 11.1 0.021 14.4 7.7 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFH43126.1 - 0.0035 16.9 9.3 0.46 10.1 6.7 2.3 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFH43126.1 - 0.04 13.9 12.2 1 9.4 8.5 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KFH43126.1 - 0.7 9.8 9.3 4.1 7.4 6.5 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.1 KFH43126.1 - 1 9.4 10.3 4 7.4 7.1 1.9 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_UBOX PF13445.1 KFH43126.1 - 1.2 8.9 6.8 29 4.4 4.7 2.2 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.1 KFH43126.1 - 1.3 8.8 11.7 17 5.2 8.1 2.5 1 1 0 1 1 1 0 zinc-RING finger domain zf-HC5HC2H PF13771.1 KFH43126.1 - 1.6 8.9 11.1 79 3.5 7.2 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain Histone PF00125.19 KFH43127.1 - 3.9e-28 97.3 0.2 5.5e-28 96.8 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFH43127.1 - 0.029 14.4 0.1 0.051 13.6 0.1 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 KFH43127.1 - 0.13 12.4 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Kinetochore component CENP-S CorA PF01544.13 KFH43128.1 - 3.1e-44 151.1 0.0 6.4e-44 150.1 0.0 1.5 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein FA_hydroxylase PF04116.8 KFH43129.1 - 2.3e-14 53.7 26.4 5.2e-14 52.6 14.0 2.4 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily NAD_binding_8 PF13450.1 KFH43130.1 - 3.8e-13 49.2 0.3 1.9e-12 47.0 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFH43130.1 - 9.1e-08 31.3 0.0 1.8e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFH43130.1 - 7.7e-07 28.3 1.6 1.2e-06 27.6 1.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KFH43130.1 - 3.1e-06 27.2 0.1 9.5e-05 22.3 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFH43130.1 - 8.3e-06 26.1 0.3 0.0002 21.7 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFH43130.1 - 2.3e-05 23.6 0.7 6.6e-05 22.1 0.1 2.0 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 KFH43130.1 - 4.5e-05 22.0 1.7 0.00014 20.5 0.4 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 KFH43130.1 - 4.8e-05 22.6 0.8 0.00012 21.2 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KFH43130.1 - 5.5e-05 22.4 0.1 0.00013 21.2 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase K_oxygenase PF13434.1 KFH43130.1 - 9.1e-05 21.5 0.0 0.28 10.0 0.0 2.6 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KFH43130.1 - 0.00052 19.8 0.5 0.019 14.7 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KFH43130.1 - 0.00087 19.4 0.7 0.0021 18.1 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFH43130.1 - 0.0016 17.4 0.1 0.0026 16.7 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 KFH43130.1 - 0.008 15.2 0.5 0.39 9.7 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.9 KFH43130.1 - 0.012 14.3 0.4 0.012 14.3 0.3 1.6 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_7 PF13241.1 KFH43130.1 - 0.022 15.0 0.0 0.049 13.9 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Peptidase_S9 PF00326.16 KFH43130.1 - 0.036 13.2 0.1 0.086 12.0 0.1 1.7 1 0 0 1 1 1 0 Prolyl oligopeptidase family GIDA PF01134.17 KFH43130.1 - 0.078 11.8 1.3 0.15 10.8 0.9 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A adh_short PF00106.20 KFH43132.1 - 1.7e-18 67.0 0.0 2.5e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH43132.1 - 4.2e-09 36.3 0.0 6e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 KR domain TRAPP PF04051.11 KFH43133.1 - 1.9e-42 144.3 0.0 2.4e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Ribosomal_L28e PF01778.12 KFH43135.1 - 2.4e-37 127.9 0.8 2.9e-37 127.6 0.6 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Glyco_hydro_3 PF00933.16 KFH43136.1 - 5.7e-87 291.4 0.0 8.1e-87 290.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KFH43136.1 - 2.6e-57 193.9 0.3 5.1e-57 193.0 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KFH43136.1 - 1.3e-23 82.6 0.0 3e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Pro-kuma_activ PF09286.6 KFH43138.1 - 4.5e-24 85.1 0.1 9e-24 84.1 0.0 1.6 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KFH43138.1 - 4.3e-10 39.2 0.0 1.7e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 Subtilase family Antig_Caf1 PF09255.5 KFH43140.1 - 0.043 13.7 0.0 0.34 10.8 0.0 2.0 2 0 0 2 2 2 0 Caf1 Capsule antigen 4HBT_2 PF13279.1 KFH43141.1 - 1.5e-17 64.1 0.0 1.7e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 KFH43141.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Thioesterase superfamily MFS_1 PF07690.11 KFH43142.1 - 2e-23 82.6 26.0 2e-23 82.6 18.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Tmemb_9 PF05434.6 KFH43142.1 - 0.055 13.2 0.0 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 TMEM9 PTR2 PF00854.16 KFH43144.1 - 2.4e-40 138.4 9.1 2.9e-23 82.2 1.3 2.2 2 0 0 2 2 2 2 POT family MFS_1 PF07690.11 KFH43144.1 - 3.3e-05 22.7 20.4 8.5e-05 21.4 11.9 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily LacAB_rpiB PF02502.13 KFH43145.1 - 1.4e-42 144.6 0.4 1.6e-42 144.4 0.3 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Peptidase_M14 PF00246.19 KFH43146.1 - 4.2e-39 134.8 0.0 6.3e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Thi4 PF01946.12 KFH43147.1 - 2.1e-104 347.6 0.1 2.6e-104 347.3 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 KFH43147.1 - 6.2e-09 35.2 0.2 5.2e-08 32.1 0.4 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFH43147.1 - 1.2e-05 25.2 0.4 3e-05 23.9 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KFH43147.1 - 3.3e-05 23.7 0.2 0.00012 21.9 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KFH43147.1 - 6.1e-05 22.0 0.3 6.1e-05 22.0 0.2 1.8 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KFH43147.1 - 0.0018 17.1 2.7 0.051 12.4 0.4 2.9 2 1 1 3 3 3 1 FAD binding domain FAD_oxidored PF12831.2 KFH43147.1 - 0.0026 16.9 0.0 0.0038 16.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KFH43147.1 - 0.0031 17.6 0.2 0.0053 16.8 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFH43147.1 - 0.0051 16.7 0.1 0.0081 16.0 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFH43147.1 - 0.031 12.7 0.2 0.24 9.8 0.2 1.9 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.14 KFH43147.1 - 0.041 12.9 0.0 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 KFH43147.1 - 0.051 13.9 0.3 0.12 12.8 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.19 KFH43148.1 - 2.9e-30 105.2 35.5 1.7e-19 69.7 9.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KFH43148.1 - 7.3e-21 74.2 40.9 1.2e-14 53.8 19.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Transgly_assoc PF04226.8 KFH43148.1 - 1.2 9.2 14.7 0.41 10.7 0.1 5.1 4 0 0 4 4 4 0 Transglycosylase associated protein V-SNARE_C PF12352.3 KFH43149.1 - 5.6e-14 51.9 0.5 1.4e-13 50.6 0.3 1.7 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KFH43149.1 - 5e-06 26.1 0.4 2.6e-05 23.8 0.0 2.2 3 0 0 3 3 3 1 Sec20 TPR_MLP1_2 PF07926.7 KFH43149.1 - 0.037 13.7 3.5 0.094 12.4 0.3 2.3 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1804 PF08822.6 KFH43149.1 - 0.053 13.2 1.1 0.13 11.9 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1804) DivIC PF04977.10 KFH43149.1 - 0.19 11.2 3.2 0.76 9.3 0.1 3.0 3 1 0 3 3 3 0 Septum formation initiator Filament PF00038.16 KFH43149.1 - 0.35 10.3 3.4 0.16 11.4 0.2 1.8 2 0 0 2 2 2 0 Intermediate filament protein PspB PF06667.7 KFH43149.1 - 0.86 9.5 2.9 2.6 8.0 2.0 1.8 1 0 0 1 1 1 0 Phage shock protein B VIT1 PF01988.14 KFH43150.1 - 3.6e-38 131.1 0.1 4.4e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 VIT family CHCH PF06747.8 KFH43151.1 - 2.2e-06 27.3 5.0 3.6e-06 26.7 3.5 1.4 1 0 0 1 1 1 1 CHCH domain zf-C2HC5 PF06221.8 KFH43152.1 - 1.2e-20 73.0 5.3 1.8e-20 72.4 3.7 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type DUF3435 PF11917.3 KFH43152.1 - 0.21 10.2 2.9 0.31 9.6 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Glyco_hydro_45 PF02015.11 KFH43153.1 - 2.5e-87 292.1 14.9 2.9e-87 291.9 10.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 AhpC-TSA_2 PF13911.1 KFH43154.1 - 2.2e-18 66.2 0.0 4.6e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Fungal_trans PF04082.13 KFH43154.1 - 3.6e-12 45.7 0.0 6.8e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Whi5 PF08528.6 KFH43155.1 - 1.8e-11 43.3 0.0 3e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Whi5 like Aminotran_5 PF00266.14 KFH43156.1 - 1.6e-20 73.1 0.0 3.7e-20 71.9 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Pyridoxal_deC PF00282.14 KFH43156.1 - 0.11 10.8 0.0 0.17 10.3 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Ldh_1_C PF02866.13 KFH43157.1 - 9.3e-44 149.2 0.0 1.3e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 KFH43157.1 - 1.4e-41 141.6 0.0 5.9e-41 139.6 0.0 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KFH43157.1 - 0.0003 19.5 0.0 0.00042 19.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KFH43157.1 - 0.0098 16.1 0.4 0.054 13.8 0.0 2.3 3 0 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_16 PF00722.16 KFH43158.1 - 2.1e-18 66.2 0.1 3.1e-18 65.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 KFH43158.1 - 8.9e-05 20.8 1.4 0.075 11.1 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) NAD_binding_10 PF13460.1 KFH43159.1 - 3.1e-13 50.1 0.1 4.1e-13 49.7 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KFH43159.1 - 1.5e-11 43.9 0.0 2e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 KFH43159.1 - 0.013 15.4 0.2 0.022 14.7 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Fungal_trans PF04082.13 KFH43160.1 - 7.4e-15 54.5 0.8 7.4e-15 54.5 0.5 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH43160.1 - 3.8e-09 36.2 9.6 6.2e-09 35.6 6.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Myb_DNA-bind_3 PF12776.2 KFH43162.1 - 6.4e-19 68.3 0.8 1.2e-18 67.5 0.0 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain TFIIA PF03153.8 KFH43162.1 - 9.1 6.0 9.7 13 5.5 6.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Str_synth PF03088.11 KFH43163.1 - 0.03 14.3 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 Strictosidine synthase p450 PF00067.17 KFH43164.1 - 1.8e-53 181.6 0.0 2.5e-53 181.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MotA_ExbB PF01618.11 KFH43164.1 - 0.16 11.6 2.8 0.11 12.1 0.4 1.8 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family Dak1 PF02733.12 KFH43165.1 - 8.1e-106 353.2 0.0 1.1e-105 352.8 0.0 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 KFH43165.1 - 1.3e-40 138.9 2.8 1.3e-40 138.9 1.9 1.8 2 0 0 2 2 2 1 DAK2 domain Hydrolase PF00702.21 KFH43166.1 - 1.2e-23 84.6 0.7 2.9e-23 83.4 0.5 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFH43166.1 - 5.4e-21 75.6 0.1 1e-20 74.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KFH43166.1 - 5.6e-21 74.6 0.0 1.2e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KFH43166.1 - 0.00021 21.1 0.0 0.002 18.0 0.0 2.4 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFH43166.1 - 0.0026 17.3 0.1 0.037 13.5 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase F-box-like PF12937.2 KFH43167.1 - 1.7e-07 30.8 0.4 4.5e-07 29.4 0.1 2.0 2 0 0 2 2 2 1 F-box-like TIM PF00121.13 KFH43168.1 - 2e-55 187.5 0.0 2.2e-55 187.3 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase DUF3753 PF12575.3 KFH43168.1 - 0.0059 16.3 0.1 0.0099 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3753) TPK_catalytic PF04263.11 KFH43169.1 - 3.7e-23 81.4 0.0 5.6e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 KFH43169.1 - 1.2e-21 76.2 0.1 1.8e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Malate_synthase PF01274.17 KFH43170.1 - 2.4e-217 722.0 0.0 2.8e-217 721.8 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.9 KFH43170.1 - 0.017 14.0 0.0 0.03 13.2 0.0 1.4 1 1 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family HIG_1_N PF04588.8 KFH43171.1 - 0.00071 19.2 0.6 0.00071 19.2 0.4 2.1 2 0 0 2 2 2 1 Hypoxia induced protein conserved region Mtc PF03820.12 KFH43171.1 - 0.0085 14.7 0.1 0.92 8.1 0.0 2.1 2 0 0 2 2 2 2 Tricarboxylate carrier RNA_pol_Rpc4 PF05132.9 KFH43172.1 - 0.11 12.4 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF1469 PF07332.6 KFH43172.1 - 3.3 7.4 5.5 0.66 9.7 0.9 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) Adaptin_N PF01602.15 KFH43173.1 - 2.4e-129 432.0 9.1 3e-129 431.7 6.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KFH43173.1 - 8.8e-17 61.5 2.6 1.2e-16 61.0 0.1 2.4 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KFH43173.1 - 2.4e-15 56.5 7.9 6.6e-10 39.1 0.6 4.7 3 1 2 5 5 5 4 HEAT repeats HEAT PF02985.17 KFH43173.1 - 2.6e-11 42.6 3.6 0.0015 18.4 0.0 5.3 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 KFH43173.1 - 0.00038 20.8 12.7 1 9.9 0.0 6.2 4 2 2 6 6 6 2 HEAT-like repeat Atx10homo_assoc PF09759.4 KFH43173.1 - 0.00042 19.9 0.1 0.57 9.9 0.0 3.9 3 1 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain CLASP_N PF12348.3 KFH43173.1 - 0.0034 16.7 1.4 2.2 7.5 0.0 2.9 3 0 0 3 3 3 2 CLASP N terminal Arm PF00514.18 KFH43173.1 - 0.015 15.1 4.4 3.9 7.4 0.0 4.6 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat T_hemolysin PF12261.3 KFH43173.1 - 0.079 12.5 0.1 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Thermostable hemolysin Senescence PF06911.7 KFH43174.1 - 0.47 10.1 5.5 0.81 9.3 3.8 1.4 1 1 0 1 1 1 0 Senescence-associated protein Rad60-SLD_2 PF13881.1 KFH43175.1 - 5.3e-12 45.6 0.0 8.4e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KFH43175.1 - 8.4e-07 28.2 0.0 1.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 KFH43175.1 - 0.00013 22.1 0.0 0.00034 20.7 0.0 1.7 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain HET PF06985.6 KFH43176.1 - 1.2e-34 119.4 0.0 2e-34 118.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ABC_tran PF00005.22 KFH43177.1 - 1.8e-22 80.1 0.0 2.9e-10 40.5 0.0 3.7 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KFH43177.1 - 2.5e-08 34.2 0.1 0.051 13.5 0.0 3.7 4 0 0 4 4 4 2 AAA domain AAA_17 PF13207.1 KFH43177.1 - 2.3e-07 31.6 0.0 0.03 15.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 KFH43177.1 - 1.9e-06 27.7 0.0 0.0037 17.1 0.1 2.4 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 KFH43177.1 - 2.6e-05 24.2 0.5 0.011 15.6 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KFH43177.1 - 5.7e-05 22.5 0.0 0.076 12.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KFH43177.1 - 0.0002 21.7 0.0 0.069 13.4 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KFH43177.1 - 0.0014 18.7 0.0 1.2 9.3 0.0 3.2 4 0 0 4 4 3 1 AAA domain Miro PF08477.8 KFH43177.1 - 0.0053 17.2 0.0 0.41 11.1 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein AAA_18 PF13238.1 KFH43177.1 - 0.0066 16.7 0.0 5.1 7.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KFH43177.1 - 0.0068 16.2 0.0 3.5 7.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KFH43177.1 - 0.0098 15.6 0.1 5.1 6.8 0.0 2.7 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 KFH43177.1 - 0.012 15.0 0.1 4.3 6.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.1 KFH43177.1 - 0.013 15.4 0.0 5.1 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KFH43177.1 - 0.017 14.5 0.1 5 6.4 0.0 2.4 2 1 0 2 2 2 0 AAA-like domain RNA_helicase PF00910.17 KFH43177.1 - 0.025 14.7 0.0 2.1 8.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 KFH43177.1 - 0.026 14.7 0.2 0.76 9.9 0.0 3.0 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KFH43177.1 - 0.049 13.5 0.0 13 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 KFH43177.1 - 0.075 12.5 0.0 0.75 9.2 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 KFH43177.1 - 0.079 12.5 0.0 9.5 5.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 KFH43177.1 - 0.081 12.5 0.0 15 5.1 0.0 2.8 2 0 0 2 2 2 0 NACHT domain ATP_bind_1 PF03029.12 KFH43177.1 - 0.11 12.0 0.0 2.6 7.4 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 KFH43177.1 - 0.12 11.8 0.0 12 5.2 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF258 PF03193.11 KFH43177.1 - 0.19 10.8 0.0 21 4.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_15 PF13175.1 KFH43177.1 - 0.3 10.0 0.0 3.5 6.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_13 PF13166.1 KFH43177.1 - 0.32 9.4 0.1 0.49 8.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain NAD_binding_10 PF13460.1 KFH43178.1 - 4.3e-07 30.1 0.0 5.3e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KFH43178.1 - 0.00031 19.7 0.0 0.00037 19.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DapB_N PF01113.15 KFH43178.1 - 0.0068 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 KFH43178.1 - 0.018 15.3 0.0 0.032 14.5 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.11 KFH43178.1 - 0.027 15.0 0.0 0.068 13.7 0.0 1.7 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DNA_mis_repair PF01119.14 KFH43180.1 - 5.2e-34 116.2 0.0 1e-33 115.3 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KFH43180.1 - 4.1e-13 49.1 0.0 7.6e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KFH43180.1 - 7.1e-11 41.8 0.0 1.7e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GHMP_kinases_N PF00288.21 KFH43181.1 - 3.7e-15 55.7 3.0 1.1e-14 54.2 2.1 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KFH43181.1 - 2e-07 31.0 0.1 5.3e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 GHMP kinases C terminal Sugar_tr PF00083.19 KFH43183.1 - 4.5e-76 256.2 20.9 5.2e-76 256.0 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH43183.1 - 5.6e-27 94.3 26.6 1.7e-24 86.1 6.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFH43183.1 - 8.4e-06 24.4 3.9 8.4e-06 24.4 2.7 3.2 2 2 2 4 4 4 1 MFS/sugar transport protein Gate PF07670.9 KFH43183.1 - 3.8 7.4 7.4 2.2 8.2 0.1 3.3 2 1 1 3 3 3 0 Nucleoside recognition Syntaxin-18_N PF10496.4 KFH43184.1 - 1.7e-12 46.9 0.0 1.4e-11 44.0 0.0 2.4 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 KFH43184.1 - 5.1e-05 22.8 4.5 5.6e-05 22.7 1.8 2.1 2 0 0 2 2 2 1 SNARE domain Synaptobrevin PF00957.16 KFH43184.1 - 0.0065 16.0 0.2 0.09 12.3 0.1 2.4 2 0 0 2 2 2 1 Synaptobrevin G-patch_2 PF12656.2 KFH43184.1 - 0.076 12.8 0.3 0.2 11.5 0.2 1.7 1 0 0 1 1 1 0 DExH-box splicing factor binding site Histone_HNS PF00816.16 KFH43184.1 - 3.1 8.3 7.3 7.8 7.0 0.1 3.4 3 1 0 3 3 3 0 H-NS histone family BLOC1_2 PF10046.4 KFH43184.1 - 9.4 6.4 11.5 1.2 9.2 4.3 2.1 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HisG PF01634.13 KFH43185.1 - 1.8e-05 24.3 0.0 3.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 ATP phosphoribosyltransferase AAA_18 PF13238.1 KFH43185.1 - 0.024 14.9 1.3 1.7 8.9 0.1 3.1 2 1 0 2 2 2 0 AAA domain ketoacyl-synt PF00109.21 KFH43187.1 - 6e-64 215.9 0.0 1.1e-63 215.1 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KFH43187.1 - 4.2e-63 213.6 0.0 6.4e-63 213.0 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KFH43187.1 - 1.1e-56 192.1 0.0 1.8e-56 191.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 KFH43187.1 - 8.5e-52 175.4 0.2 2.5e-51 173.9 0.1 1.9 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KFH43187.1 - 1.6e-37 128.9 0.1 7.5e-37 126.8 0.1 2.3 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KFH43187.1 - 5e-32 110.2 0.1 1.3e-31 108.8 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KFH43187.1 - 2.5e-19 69.5 0.0 1.1e-18 67.5 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KFH43187.1 - 2.1e-16 59.6 0.2 3.2e-15 55.8 0.0 2.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFH43187.1 - 2.1e-11 44.8 0.0 8.2e-11 42.8 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 KFH43187.1 - 6e-11 42.1 0.0 2.8e-10 39.9 0.0 2.1 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH43187.1 - 8.3e-10 39.0 0.0 4.9e-09 36.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH43187.1 - 1e-09 38.9 0.0 4.1e-09 36.9 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH43187.1 - 1.4e-07 31.3 0.0 3.1e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 KFH43187.1 - 4.9e-07 29.4 0.1 1.3e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.13 KFH43187.1 - 2.7e-06 26.6 0.0 6.2e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.20 KFH43187.1 - 3.4e-06 27.2 0.1 1.1e-05 25.6 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KFH43187.1 - 0.0031 16.5 0.1 0.0058 15.6 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 KFH43187.1 - 0.017 14.7 0.3 0.067 12.8 0.2 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PCMT PF01135.14 KFH43187.1 - 0.03 13.8 0.1 7.1 6.1 0.0 2.4 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 3Beta_HSD PF01073.14 KFH43187.1 - 0.13 10.9 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Crystall_2 PF09076.5 KFH43188.1 - 0.00034 20.3 0.4 0.0006 19.5 0.3 1.4 1 0 0 1 1 1 1 Beta/Gamma crystallin GFO_IDH_MocA PF01408.17 KFH43189.1 - 3e-12 47.0 0.0 6.5e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KFH43189.1 - 0.004 16.9 0.0 0.0084 15.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 KFH43189.1 - 0.0082 16.4 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KFH43189.1 - 0.015 15.3 0.0 0.04 14.0 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF1077 PF06417.7 KFH43190.1 - 1.1e-53 179.9 3.6 1.3e-53 179.6 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) DEAD PF00270.24 KFH43191.1 - 1.9e-41 141.3 0.0 4.4e-41 140.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFH43191.1 - 2.3e-18 65.8 0.0 5.2e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KFH43191.1 - 7.8e-17 60.5 0.1 3e-16 58.6 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.10 KFH43191.1 - 0.046 13.5 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DEAD PF00270.24 KFH43193.1 - 2.9e-43 147.3 0.2 6e-42 142.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFH43193.1 - 1.1e-22 79.6 0.0 3.1e-22 78.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFH43193.1 - 7.7e-06 25.8 0.0 1.3e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KFH43193.1 - 0.00018 20.4 0.0 0.017 13.9 0.0 2.2 1 1 1 2 2 2 2 SNF2 family N-terminal domain AAA_30 PF13604.1 KFH43193.1 - 0.036 13.6 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.9 KFH43193.1 - 0.044 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Helicase HD_4 PF13328.1 KFH43193.1 - 0.059 13.0 0.1 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 HD domain AAA_22 PF13401.1 KFH43193.1 - 0.12 12.5 1.5 0.76 9.9 1.0 2.4 2 2 0 2 2 2 0 AAA domain SecA_DEAD PF07517.9 KFH43193.1 - 0.18 11.0 0.5 0.53 9.5 0.4 1.7 1 1 0 1 1 1 0 SecA DEAD-like domain UMP1 PF05348.6 KFH43194.1 - 7.8e-26 90.5 0.0 9.5e-26 90.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Aa_trans PF01490.13 KFH43195.1 - 2.6e-31 108.5 27.6 3e-31 108.3 19.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 KFH43195.1 - 2.4e-06 26.3 34.9 1.2e-05 24.1 16.0 2.8 1 1 1 2 2 2 2 Amino acid permease DUF2583 PF10762.4 KFH43195.1 - 0.65 10.1 4.4 0.48 10.5 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2583) BUD22 PF09073.5 KFH43196.1 - 0.042 12.9 4.9 0.069 12.2 3.4 1.3 1 0 0 1 1 1 0 BUD22 U79_P34 PF03064.11 KFH43196.1 - 0.047 13.2 0.3 0.28 10.6 0.1 2.0 2 0 0 2 2 2 0 HSV U79 / HCMV P34 Astro_capsid PF03115.9 KFH43196.1 - 0.048 11.9 0.7 0.072 11.3 0.5 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Daxx PF03344.10 KFH43196.1 - 0.19 10.1 6.0 0.3 9.5 4.2 1.2 1 0 0 1 1 1 0 Daxx Family DUF3306 PF11748.3 KFH43196.1 - 0.28 11.8 5.9 1.1 9.9 4.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) DUF202 PF02656.10 KFH43197.1 - 1.1e-16 60.7 0.1 1.8e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Aminotran_1_2 PF00155.16 KFH43199.1 - 2.8e-89 299.6 0.1 4.3e-89 298.9 0.0 1.3 2 0 0 2 2 2 1 Aminotransferase class I and II MFS_1 PF07690.11 KFH43200.1 - 1.1e-52 178.9 22.4 1.5e-52 178.5 13.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH43200.1 - 9.5e-09 34.3 10.2 9.5e-09 34.3 7.1 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 KFH43200.1 - 0.036 12.1 0.7 0.064 11.2 0.5 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family ABC2_membrane PF01061.19 KFH43201.1 - 4e-90 300.5 47.7 1.8e-47 161.2 10.1 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KFH43201.1 - 1.5e-39 135.4 0.0 5.3e-19 68.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KFH43201.1 - 1.4e-24 85.6 6.4 5.9e-24 83.6 0.0 3.0 3 0 0 3 3 2 1 CDR ABC transporter ABC2_membrane_3 PF12698.2 KFH43201.1 - 1.9e-19 69.9 18.1 1e-11 44.4 2.4 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 KFH43201.1 - 4.1e-05 23.0 0.3 0.0074 15.7 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KFH43201.1 - 8.9e-05 22.6 0.1 0.041 14.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KFH43201.1 - 0.00012 21.2 0.1 0.0068 15.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 KFH43201.1 - 0.00018 21.5 0.0 0.99 9.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain ABC_trans_N PF14510.1 KFH43201.1 - 0.00088 19.3 0.0 0.0019 18.2 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_28 PF13521.1 KFH43201.1 - 0.0034 17.3 1.8 0.45 10.4 0.5 2.5 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 KFH43201.1 - 0.0039 16.6 0.7 1.4 8.3 0.2 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 KFH43201.1 - 0.0045 17.0 0.2 0.29 11.1 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.14 KFH43201.1 - 0.0047 16.3 1.1 0.34 10.3 0.3 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 KFH43201.1 - 0.0097 16.7 0.0 1.1 10.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KFH43201.1 - 0.012 15.9 0.1 1.4 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KFH43201.1 - 0.015 14.7 0.5 0.079 12.5 0.1 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain UPF0079 PF02367.12 KFH43201.1 - 0.083 12.5 0.9 5.1 6.7 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 KFH43201.1 - 0.099 12.4 1.8 12 5.6 0.2 2.6 2 0 0 2 2 2 0 Part of AAA domain Miro PF08477.8 KFH43201.1 - 0.12 12.9 0.0 3.2 8.2 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA PF00004.24 KFH43201.1 - 0.17 12.1 0.1 34 4.6 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KFH43201.1 - 0.2 11.2 0.5 1.8 8.1 0.1 2.2 2 0 0 2 2 2 0 NACHT domain HsbA PF12296.3 KFH43202.1 - 1.2e-07 31.6 0.1 1.7e-07 31.1 0.0 1.3 1 1 0 1 1 1 1 Hydrophobic surface binding protein A Transpep_BrtH PF14399.1 KFH43202.1 - 0.063 12.5 0.1 0.18 11.0 0.0 1.6 2 0 0 2 2 2 0 NlpC/p60-like transpeptidase Sec8_exocyst PF04048.9 KFH43202.1 - 0.065 12.8 0.0 0.26 10.9 0.0 1.8 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain PilJ PF13675.1 KFH43202.1 - 0.16 12.2 1.1 1.7 9.0 0.3 2.5 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term HD PF01966.17 KFH43203.1 - 3.8e-05 23.6 0.4 7.5e-05 22.7 0.3 1.5 1 0 0 1 1 1 1 HD domain ARL6IP6 PF15062.1 KFH43204.1 - 0.01 15.7 0.1 0.045 13.6 0.0 2.1 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix GMP_synt_C PF00958.17 KFH43204.1 - 0.011 15.4 0.0 1.7 8.4 0.0 2.5 2 0 0 2 2 2 0 GMP synthase C terminal domain SMN PF06003.7 KFH43204.1 - 0.054 12.6 0.0 0.086 11.9 0.0 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) L31 PF09784.4 KFH43205.1 - 2.3e-45 152.9 1.3 2.5e-45 152.7 0.9 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 EthD PF07110.6 KFH43206.1 - 8.6e-22 77.8 0.8 1.1e-21 77.5 0.5 1.1 1 0 0 1 1 1 1 EthD domain Ras PF00071.17 KFH43207.1 - 5e-58 195.0 0.0 6.7e-58 194.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFH43207.1 - 2.9e-20 72.9 0.0 5e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFH43207.1 - 7.6e-14 51.3 0.0 1.4e-13 50.4 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFH43207.1 - 6.3e-06 25.7 0.0 1.6e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFH43207.1 - 6.3e-06 25.4 0.0 7.9e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFH43207.1 - 0.00013 21.9 0.0 0.00034 20.5 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KFH43207.1 - 0.0052 16.8 0.0 0.013 15.5 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFH43207.1 - 0.029 14.5 0.0 0.18 11.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain PI3_PI4_kinase PF00454.22 KFH43208.1 - 3.2e-43 147.8 0.0 6.4e-43 146.9 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 KFH43208.1 - 8.8e-39 132.7 0.2 8.8e-39 132.7 0.1 2.6 3 0 0 3 3 3 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 KFH43208.1 - 4.5e-10 38.7 1.0 1.3e-09 37.3 0.1 2.3 2 0 0 2 2 2 1 FATC domain CBFD_NFYB_HMF PF00808.18 KFH43209.1 - 2e-13 50.1 1.8 3.2e-13 49.5 1.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFH43209.1 - 5.7e-06 26.3 0.2 1e-05 25.5 0.2 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 zf-C3HC4_3 PF13920.1 KFH43210.1 - 9.4e-10 38.0 7.2 1.4e-09 37.4 5.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFH43210.1 - 2.2e-08 33.7 9.2 3.7e-08 33.0 6.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFH43210.1 - 7.1e-08 32.3 9.1 1.1e-07 31.6 6.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFH43210.1 - 2.2e-06 27.1 9.3 3.5e-06 26.5 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFH43210.1 - 2.2e-05 24.0 8.9 3.6e-05 23.3 6.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KFH43210.1 - 4.3e-05 23.2 3.7 7.5e-05 22.4 2.5 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 KFH43210.1 - 0.0028 17.1 3.5 0.0068 15.9 2.4 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 KFH43210.1 - 0.01 15.4 6.1 0.018 14.6 4.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KFH43210.1 - 0.029 14.2 8.5 0.054 13.3 5.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KFH43210.1 - 0.042 13.9 3.6 0.078 13.0 2.5 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KFH43210.1 - 0.059 13.1 3.3 0.2 11.4 2.3 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-MIZ PF02891.15 KFH43210.1 - 0.75 9.3 6.9 1.4 8.4 4.8 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger FANCL_C PF11793.3 KFH43210.1 - 7.7 6.5 8.2 4.8e+02 0.8 5.7 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain DNA_pol_A PF00476.15 KFH43211.1 - 5.7e-101 337.8 0.0 1.3e-100 336.7 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 KFH43211.1 - 0.45 9.9 2.6 7 6.0 0.6 3.2 2 1 0 2 2 2 0 3'-5' exonuclease DUF788 PF05620.6 KFH43212.1 - 1.2e-40 139.1 0.0 1.3e-40 139.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) HSA PF07529.8 KFH43213.1 - 1.5e-18 66.3 3.3 1.5e-18 66.3 2.3 3.7 3 0 0 3 3 3 2 HSA Myb_DNA-bind_6 PF13921.1 KFH43213.1 - 5.4e-14 52.0 0.3 1.7e-13 50.4 0.2 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain EFF-AFF PF14884.1 KFH43213.1 - 6.7 4.6 6.1 13 3.7 4.2 1.3 1 0 0 1 1 1 0 Type I membrane glycoproteins cell-cell fusogen Histone PF00125.19 KFH43214.1 - 1.6e-15 56.9 0.1 1.9e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 KFH43214.1 - 0.0001 22.1 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 KFH43214.1 - 0.00011 22.3 0.1 0.00016 21.8 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KFH43214.1 - 0.00014 21.7 0.2 0.00031 20.7 0.0 1.7 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KFH43214.1 - 0.017 14.8 0.0 0.021 14.5 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KFH43214.1 - 0.021 14.0 0.0 0.022 14.0 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Glyco_transf_28 PF03033.15 KFH43215.1 - 3.5e-17 62.4 0.0 8e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KFH43215.1 - 4.9e-06 25.3 0.0 9.3e-06 24.4 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KFH43215.1 - 0.26 10.9 0.0 0.49 10.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain FAD_binding_4 PF01565.18 KFH43217.1 - 1.2e-11 44.2 4.1 8.8e-06 25.2 1.3 2.7 2 1 1 3 3 3 2 FAD binding domain Arf PF00025.16 KFH43218.1 - 1.4e-39 135.1 0.0 1.8e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KFH43218.1 - 6.5e-12 44.8 0.0 2.8e-07 29.5 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 KFH43218.1 - 3e-09 36.4 0.0 8.2e-09 35.0 0.0 1.6 1 1 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KFH43218.1 - 1e-07 31.3 0.0 1.1e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KFH43218.1 - 2.9e-07 29.9 0.0 4.9e-07 29.1 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 KFH43218.1 - 6e-05 22.5 0.1 0.00016 21.1 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 KFH43218.1 - 0.00014 22.3 0.0 0.00046 20.6 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KFH43218.1 - 0.0068 16.3 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ArgK PF03308.11 KFH43218.1 - 0.086 11.6 0.0 0.19 10.4 0.1 1.5 2 0 0 2 2 2 0 ArgK protein Nup88 PF10168.4 KFH43220.1 - 0.0011 16.9 14.1 0.18 9.6 0.0 3.6 3 1 1 4 4 4 3 Nuclear pore component WD40 PF00400.27 KFH43220.1 - 0.0024 17.6 0.4 0.071 13.0 0.2 2.9 2 0 0 2 2 2 1 WD domain, G-beta repeat TMEM238 PF15125.1 KFH43220.1 - 0.16 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 TMEM238 protein family Nup54 PF13874.1 KFH43220.1 - 1.5 8.4 11.0 0.46 10.1 5.0 1.9 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF972 PF06156.8 KFH43220.1 - 2.2 8.6 6.9 2.6 8.4 1.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Syntaxin PF00804.20 KFH43220.1 - 3.9 7.6 7.8 1.3 9.2 2.2 2.3 1 1 1 2 2 2 0 Syntaxin IncA PF04156.9 KFH43220.1 - 6.9 6.2 15.8 1.5 8.3 4.1 2.3 1 1 1 2 2 2 0 IncA protein Cwf_Cwc_15 PF04889.7 KFH43221.1 - 9.6e-82 274.3 13.1 1.1e-81 274.1 9.1 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF1509 PF07420.6 KFH43221.1 - 0.0059 15.9 5.1 0.0071 15.6 3.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1509) GEMIN8 PF15348.1 KFH43221.1 - 0.028 14.4 6.6 0.033 14.2 4.6 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DUF2890 PF11081.3 KFH43221.1 - 0.16 12.0 9.8 0.27 11.2 6.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Nop14 PF04147.7 KFH43221.1 - 2.2 6.0 23.2 2.6 5.8 16.1 1.2 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.10 KFH43221.1 - 3.4 6.1 5.7 3.9 6.0 3.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.9 KFH43221.1 - 3.5 5.5 16.0 3.8 5.4 11.1 1.2 1 0 0 1 1 1 0 CDC45-like protein RNA_polI_A34 PF08208.6 KFH43221.1 - 4 7.0 10.2 5.7 6.5 7.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF1510 PF07423.6 KFH43221.1 - 8.2 5.7 13.1 11 5.2 9.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Med21 PF11221.3 KFH43221.1 - 9.4 6.1 8.0 24 4.9 5.6 1.6 1 0 0 1 1 1 0 Subunit 21 of Mediator complex EBP PF05241.7 KFH43222.1 - 3.5e-53 179.5 8.4 4.3e-53 179.2 5.8 1.0 1 0 0 1 1 1 1 Emopamil binding protein Sedlin_N PF04628.8 KFH43223.1 - 2.2e-40 137.5 0.0 2.7e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 KFH43223.1 - 0.004 16.8 0.2 0.11 12.2 0.0 2.1 1 1 1 2 2 2 1 Sybindin-like family Kri1_C PF12936.2 KFH43224.1 - 7.7e-26 89.8 0.0 7.7e-26 89.8 0.0 5.0 6 2 1 7 7 7 1 KRI1-like family C-terminal Kri1 PF05178.7 KFH43224.1 - 2.4e-25 88.7 22.9 2.4e-25 88.7 15.9 6.8 5 3 1 6 6 6 1 KRI1-like family DUF4381 PF14316.1 KFH43224.1 - 0.31 11.1 1.5 0.98 9.5 1.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Cullin PF00888.17 KFH43225.1 - 1.1e-116 390.7 0.0 1.6e-116 390.2 0.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KFH43225.1 - 2e-19 69.1 5.2 3.4e-17 62.0 0.3 3.0 3 0 0 3 3 3 2 Cullin protein neddylation domain Cation_efflux PF01545.16 KFH43226.1 - 1.7e-53 181.5 2.2 2.1e-53 181.2 1.5 1.1 1 0 0 1 1 1 1 Cation efflux family DUF3414 PF11894.3 KFH43227.1 - 0 1268.8 0.0 0 1268.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Kinetochor_Ybp2 PF08568.5 KFH43228.1 - 4.4e-96 322.5 0.0 4.8e-96 322.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin zf-C3HC4_3 PF13920.1 KFH43229.1 - 0.0014 18.2 11.6 0.0023 17.5 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KFH43229.1 - 0.025 14.3 7.1 0.038 13.7 4.9 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 KFH43229.1 - 0.78 9.5 13.0 1.2 8.8 9.0 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFH43229.1 - 2.1 8.4 13.5 3.3 7.8 9.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PI3_PI4_kinase PF00454.22 KFH43231.1 - 2.8e-31 108.8 0.0 4.5e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 KFH43231.1 - 3.3e-20 71.5 0.0 6.8e-20 70.5 0.0 1.6 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 Med3 PF11593.3 KFH43231.1 - 0.066 12.4 0.0 0.066 12.4 0.0 3.0 2 1 1 3 3 3 0 Mediator complex subunit 3 fungal PI3Ka PF00613.15 KFH43231.1 - 0.26 10.4 0.5 0.47 9.5 0.3 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Na_H_Exchanger PF00999.16 KFH43232.1 - 3.9e-68 229.7 41.4 4.9e-68 229.3 28.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Abhydrolase_3 PF07859.8 KFH43233.1 - 4.9e-20 72.0 0.0 6.4e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KFH43233.1 - 3.6e-13 48.8 0.0 1.3e-05 24.0 0.1 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KFH43233.1 - 0.0061 16.3 0.0 0.011 15.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family G-patch_2 PF12656.2 KFH43234.1 - 1e-22 79.7 0.1 1e-22 79.7 0.1 3.1 3 0 0 3 3 3 1 DExH-box splicing factor binding site G-patch PF01585.18 KFH43234.1 - 0.0026 17.4 0.8 0.0096 15.6 0.5 2.1 1 0 0 1 1 1 1 G-patch domain TPR_1 PF00515.23 KFH43235.1 - 5.4e-35 117.5 15.2 1.9e-06 27.2 0.0 7.9 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_11 PF13414.1 KFH43235.1 - 6.4e-35 118.6 21.3 9.5e-11 41.1 2.4 7.4 4 1 4 8 8 8 7 TPR repeat TPR_2 PF07719.12 KFH43235.1 - 3.7e-29 98.2 29.3 1.7e-05 24.3 0.0 9.7 11 0 0 11 11 11 7 Tetratricopeptide repeat Apc3 PF12895.2 KFH43235.1 - 1.7e-24 85.7 15.6 5.8e-18 64.7 0.0 4.8 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KFH43235.1 - 3.7e-22 76.3 0.5 0.0025 17.4 0.0 7.7 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 KFH43235.1 - 5.5e-21 74.2 17.1 5.7e-05 22.9 1.2 7.0 4 2 5 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.1 KFH43235.1 - 1e-20 73.8 29.7 3.2e-07 30.8 1.7 8.3 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.1 KFH43235.1 - 1.7e-18 64.8 7.2 0.024 14.4 0.0 7.3 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 KFH43235.1 - 8.9e-18 63.1 24.3 0.11 13.2 0.1 10.2 4 1 5 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.1 KFH43235.1 - 2e-15 56.8 15.0 0.00089 19.5 0.3 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 KFH43235.1 - 3.3e-14 51.8 9.0 0.17 12.1 0.1 9.1 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.1 KFH43235.1 - 4.7e-09 36.1 14.9 0.25 11.8 0.0 8.9 9 0 0 9 9 9 1 Tetratricopeptide repeat DUF2225 PF09986.4 KFH43235.1 - 0.044 13.2 1.1 4.7 6.6 0.4 3.2 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_20 PF14561.1 KFH43235.1 - 0.17 12.0 9.1 0.19 11.8 0.4 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 KFH43235.1 - 0.3 10.9 6.0 2 8.3 0.2 4.2 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain TPR_9 PF13371.1 KFH43235.1 - 0.94 9.3 12.7 19 5.1 0.1 5.2 4 2 2 6 6 6 0 Tetratricopeptide repeat APP_E2 PF12925.2 KFH43235.1 - 1.2 8.7 4.2 23 4.5 0.4 3.5 1 1 1 3 3 3 0 E2 domain of amyloid precursor protein PrpF PF04303.8 KFH43236.1 - 8.4e-86 288.0 0.0 9.7e-86 287.8 0.0 1.0 1 0 0 1 1 1 1 PrpF protein RNase_PH PF01138.16 KFH43237.1 - 9.6e-18 64.7 0.0 1.4e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KFH43237.1 - 2.4e-07 30.5 0.0 4.3e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Fungal_trans PF04082.13 KFH43238.1 - 5.4e-30 104.1 0.0 9.2e-30 103.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH43238.1 - 1.7e-09 37.4 10.9 2.7e-09 36.7 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2235 PF09994.4 KFH43239.1 - 3.6e-104 348.0 1.5 3.6e-104 348.0 1.0 2.1 2 0 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Peptidase_C50 PF03568.12 KFH43240.1 - 3.8e-111 371.4 0.0 7.3e-111 370.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.1 KFH43240.1 - 1.7e-12 47.1 12.8 0.0011 18.8 0.1 6.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 KFH43240.1 - 0.014 15.0 9.8 1.1 9.2 0.1 4.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFH43240.1 - 0.025 14.4 11.1 32 4.7 0.1 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFH43240.1 - 0.19 11.4 11.8 8.6 6.0 0.1 5.6 6 1 0 6 6 6 0 TPR repeat TPR_7 PF13176.1 KFH43240.1 - 9 6.3 7.7 7.5 6.6 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat RRM_1 PF00076.17 KFH43241.1 - 3.8e-16 58.4 0.0 5.8e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH43241.1 - 1.8e-11 43.8 0.0 2.8e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH43241.1 - 2.7e-08 33.5 0.0 4.3e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SIR2 PF02146.12 KFH43242.1 - 1.5e-30 106.2 0.0 2.5e-30 105.5 0.0 1.3 1 1 0 1 1 1 1 Sir2 family CENP-B_dimeris PF09026.5 KFH43243.1 - 0.015 15.5 0.5 0.03 14.5 0.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FGGY_C PF02782.11 KFH43244.1 - 1.1e-23 83.9 0.0 1.3e-22 80.3 0.0 2.2 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KFH43244.1 - 2.2e-21 76.2 0.0 3.9e-19 68.9 0.0 2.5 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain DUF3659 PF12396.3 KFH43244.1 - 0.25 11.0 1.9 0.75 9.5 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3659) Glyco_transf_41 PF13844.1 KFH43246.1 - 1.5e-95 319.9 0.1 1.6e-49 168.1 0.0 3.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_11 PF13414.1 KFH43246.1 - 3.5e-22 77.8 1.6 1.9e-05 24.2 0.1 5.6 4 1 1 5 5 5 4 TPR repeat TPR_1 PF00515.23 KFH43246.1 - 8.9e-22 75.7 0.0 0.00016 21.0 0.0 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 KFH43246.1 - 2.2e-19 67.7 0.1 0.011 15.6 0.0 6.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 KFH43246.1 - 3.5e-14 51.4 0.0 0.0043 16.7 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFH43246.1 - 2.3e-13 49.8 6.5 8.1e-06 25.6 0.1 4.9 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 KFH43246.1 - 1.1e-12 48.1 4.7 0.035 14.7 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFH43246.1 - 4.6e-12 45.4 3.7 0.016 15.7 0.0 6.1 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFH43246.1 - 1.2e-10 40.7 0.0 0.023 14.8 0.0 5.4 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 KFH43246.1 - 3.1e-08 33.2 2.7 0.28 11.1 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFH43246.1 - 9.6e-07 28.1 2.3 0.095 12.5 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFH43246.1 - 0.00017 21.7 0.5 43 4.8 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFH43246.1 - 0.00045 20.5 1.3 4.3 7.7 0.1 3.9 3 1 1 4 4 3 1 Tetratricopeptide repeat Apc3 PF12895.2 KFH43246.1 - 0.00069 19.7 0.1 0.36 10.9 0.0 3.3 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 KFH43246.1 - 0.019 14.0 0.0 1.6 7.7 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 KFH43246.1 - 0.024 14.4 3.6 1.9 8.3 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.12 KFH43246.1 - 0.032 14.5 0.4 15 5.8 0.2 2.8 2 0 0 2 2 2 0 Bacterial transcriptional activator domain NAD_binding_6 PF08030.7 KFH43247.1 - 3.8e-06 26.8 0.0 0.00088 19.2 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 KFH43247.1 - 8.8e-05 23.0 0.0 0.097 13.2 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain Sec23_trunk PF04811.10 KFH43248.1 - 3.8e-79 265.4 0.0 5.3e-79 265.0 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KFH43248.1 - 2.4e-34 116.8 0.2 6.2e-34 115.5 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KFH43248.1 - 2.5e-30 104.8 0.4 5.6e-30 103.7 0.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KFH43248.1 - 1.6e-16 59.5 6.4 3.3e-16 58.5 4.5 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KFH43248.1 - 3e-13 49.2 0.0 7.9e-13 47.9 0.0 1.8 2 0 0 2 2 2 1 Gelsolin repeat WD40 PF00400.27 KFH43249.1 - 9.4e-35 117.2 9.1 4.4e-07 29.5 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 KFH43249.1 - 2e-08 34.2 0.1 0.0003 20.5 0.0 3.0 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A PPR PF01535.15 KFH43250.1 - 0.19 11.7 0.1 17 5.6 0.0 3.6 4 0 0 4 4 4 0 PPR repeat Cation_efflux PF01545.16 KFH43251.1 - 7.7e-26 90.8 8.1 9.7e-26 90.4 5.6 1.1 1 0 0 1 1 1 1 Cation efflux family FA_desaturase PF00487.19 KFH43251.1 - 0.27 10.6 1.7 0.46 9.8 0.8 1.6 1 1 0 1 1 1 0 Fatty acid desaturase DUF4212 PF13937.1 KFH43251.1 - 5.4 7.0 6.6 1 9.3 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) DUF2414 PF10309.4 KFH43252.1 - 3.3e-20 71.5 0.0 5.5e-20 70.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) DNA_pol_lambd_f PF10391.4 KFH43254.1 - 2.6e-22 78.1 0.8 5.5e-22 77.0 0.6 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.1 KFH43254.1 - 2.1e-21 76.0 0.0 3.8e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 KFH43254.1 - 4.7e-20 71.0 0.1 9e-20 70.1 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.1 KFH43254.1 - 1.8e-11 44.0 0.0 3.7e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.1 KFH43254.1 - 0.0014 18.7 0.0 0.014 15.5 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 KFH43254.1 - 0.016 15.5 0.0 0.038 14.3 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain DUF2838 PF10998.3 KFH43255.1 - 3.3e-44 149.3 9.5 3.3e-44 149.3 6.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Apolipoprotein PF01442.13 KFH43255.1 - 0.0004 19.9 0.0 0.057 12.9 0.0 2.1 2 0 0 2 2 2 2 Apolipoprotein A1/A4/E domain IncA PF04156.9 KFH43255.1 - 0.019 14.5 1.0 0.04 13.5 0.7 1.4 1 0 0 1 1 1 0 IncA protein Eco57I PF07669.6 KFH43256.1 - 0.05 13.9 0.1 0.06 13.6 0.0 1.2 1 0 0 1 1 1 0 Eco57I restriction-modification methylase Bd3614_N PF14442.1 KFH43257.1 - 0.78 9.7 4.7 1.2 9.1 3.2 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal Adaptin_N PF01602.15 KFH43258.1 - 4.5e-141 470.7 4.6 5.3e-141 470.5 3.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 KFH43258.1 - 1.9e-14 53.9 0.1 1.9e-14 53.9 0.1 2.0 2 0 0 2 2 2 1 Adaptin C-terminal domain HEAT_2 PF13646.1 KFH43258.1 - 5.8e-07 29.7 0.6 0.098 12.9 0.0 4.5 3 2 0 3 3 3 2 HEAT repeats TIP120 PF08623.5 KFH43258.1 - 0.0044 16.6 0.3 0.044 13.3 0.0 2.7 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) HEAT_EZ PF13513.1 KFH43258.1 - 0.012 16.0 3.5 11 6.6 0.1 5.2 4 2 0 4 4 4 0 HEAT-like repeat RIX1 PF08167.7 KFH43258.1 - 0.027 14.1 0.2 0.62 9.7 0.0 2.9 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis HEAT PF02985.17 KFH43258.1 - 0.034 14.2 5.4 13 6.2 0.0 5.4 5 1 1 6 6 6 0 HEAT repeat Cnd1 PF12717.2 KFH43258.1 - 0.037 13.8 9.3 0.02 14.7 1.0 3.7 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 KFH43258.1 - 0.04 13.7 0.9 78 3.3 0.1 5.5 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat KAR9 PF08580.5 KFH43258.1 - 0.49 8.5 4.0 0.85 7.8 2.8 1.3 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Peptidase_M14 PF00246.19 KFH43259.1 - 2.1e-65 221.0 0.5 4.6e-65 219.9 0.0 1.7 2 0 0 2 2 2 1 Zinc carboxypeptidase APG6 PF04111.7 KFH43260.1 - 0.0083 15.2 2.1 0.012 14.6 1.5 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 IncA PF04156.9 KFH43260.1 - 0.022 14.3 3.3 0.038 13.5 2.3 1.3 1 0 0 1 1 1 0 IncA protein Tropomyosin_1 PF12718.2 KFH43260.1 - 0.31 10.8 8.8 0.57 10.0 6.1 1.4 1 0 0 1 1 1 0 Tropomyosin like DUF4407 PF14362.1 KFH43260.1 - 0.62 8.9 2.3 0.95 8.3 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OEP PF02321.13 KFH43260.1 - 8.9 5.8 13.2 0.12 11.9 4.1 1.5 2 0 0 2 2 2 0 Outer membrane efflux protein TFIIE_alpha PF02002.12 KFH43261.1 - 7.8e-14 51.0 0.3 1.6e-13 50.0 0.2 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit zf-CHY PF05495.7 KFH43261.1 - 0.042 14.0 1.6 0.086 13.0 1.1 1.5 1 0 0 1 1 1 0 CHY zinc finger DZR PF12773.2 KFH43261.1 - 0.16 11.8 0.7 0.36 10.6 0.5 1.5 1 0 0 1 1 1 0 Double zinc ribbon SMC_N PF02463.14 KFH43262.1 - 2e-51 174.3 25.9 1e-50 172.0 18.0 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KFH43262.1 - 6e-29 100.4 0.0 4.1e-28 97.7 0.0 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 KFH43262.1 - 5.1e-13 49.7 14.2 5.1e-13 49.7 9.8 6.5 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 KFH43262.1 - 3.3e-09 37.1 9.5 7.5e-05 22.8 1.4 3.3 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KFH43262.1 - 2.2e-08 33.4 0.0 4.5e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 KFH43262.1 - 2.5e-08 33.4 25.3 0.00028 20.1 1.2 4.9 3 2 2 6 6 6 5 Reovirus sigma C capsid protein AAA_13 PF13166.1 KFH43262.1 - 0.00012 20.7 27.2 0.00012 20.7 18.9 6.5 4 2 5 9 9 9 5 AAA domain SbcCD_C PF13558.1 KFH43262.1 - 0.0047 16.8 0.0 0.027 14.4 0.0 2.4 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit WEMBL PF05701.6 KFH43262.1 - 0.19 10.1 111.8 0.063 11.7 4.6 4.0 3 2 0 3 3 3 0 Weak chloroplast movement under blue light AAA_22 PF13401.1 KFH43262.1 - 6.2 6.9 8.0 9.9 6.3 0.0 4.5 5 0 0 5 5 5 0 AAA domain Ndufs5 PF10200.4 KFH43264.1 - 1.2e-05 25.1 0.0 1.4e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa COX6B PF02297.12 KFH43264.1 - 0.024 14.6 0.1 0.039 13.9 0.1 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb DUF3128 PF11326.3 KFH43264.1 - 0.03 14.4 0.3 0.063 13.4 0.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) TPR_16 PF13432.1 KFH43264.1 - 0.037 14.7 0.1 0.053 14.2 0.1 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat SNARE PF05739.14 KFH43265.1 - 1.6e-19 69.3 2.8 5e-19 67.7 1.9 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 KFH43265.1 - 2.6e-11 43.5 0.8 2.6e-11 43.5 0.5 2.5 2 1 0 2 2 2 1 Syntaxin DUF2173 PF09941.4 KFH43265.1 - 0.014 15.2 0.0 1.5 8.8 0.0 2.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2173) LRR19-TM PF15176.1 KFH43265.1 - 0.019 14.6 0.1 0.078 12.6 0.0 2.0 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain MCPsignal PF00015.16 KFH43265.1 - 0.025 14.0 10.0 0.048 13.2 1.2 2.5 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Cauli_DNA-bind PF03310.8 KFH43265.1 - 0.24 11.2 5.3 0.091 12.6 0.8 2.2 2 1 1 3 3 3 0 Caulimovirus DNA-binding protein SlyX PF04102.7 KFH43265.1 - 0.74 10.2 5.1 4.9 7.6 0.4 3.1 2 1 1 3 3 3 0 SlyX Bacillus_HBL PF05791.6 KFH43265.1 - 1.3 8.3 5.8 0.34 10.2 0.2 2.5 3 1 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) SRP72 PF08492.7 KFH43266.1 - 1.6e-15 57.1 8.3 1.6e-15 57.1 5.8 2.5 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_14 PF13428.1 KFH43266.1 - 0.00026 21.3 25.8 0.29 11.8 0.0 8.9 7 2 2 9 9 9 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFH43266.1 - 0.00063 20.0 20.8 0.19 12.0 0.1 6.8 4 3 1 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFH43266.1 - 0.0031 17.2 16.0 0.37 10.8 0.0 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFH43266.1 - 0.0044 16.5 1.9 3 7.5 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 KFH43266.1 - 0.0062 16.6 5.2 2 8.6 0.1 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 SPO22 PF08631.5 KFH43266.1 - 0.0089 15.1 0.1 0.054 12.5 0.0 2.2 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like TPR_7 PF13176.1 KFH43266.1 - 0.024 14.4 2.2 1.8 8.5 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFH43266.1 - 0.057 13.0 9.9 0.045 13.4 0.7 4.4 4 2 1 6 6 6 0 TPR repeat TPR_8 PF13181.1 KFH43266.1 - 0.12 12.1 0.6 1.9 8.4 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 KFH43266.1 - 0.14 12.1 14.0 0.025 14.4 1.2 5.0 4 2 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.15 KFH43266.1 - 0.15 12.0 0.0 3.6 7.7 0.0 2.8 2 0 0 2 2 2 0 PPR repeat TPR_6 PF13174.1 KFH43266.1 - 1.3 9.6 11.0 1.3 9.6 0.2 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFH43266.1 - 4 8.2 30.2 4 8.2 1.1 6.7 6 2 2 8 8 7 0 Tetratricopeptide repeat TPR_4 PF07721.9 KFH43266.1 - 5.5 7.7 14.4 5.2 7.8 0.2 5.5 7 0 0 7 7 5 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.26 KFH43268.1 - 9.7e-21 73.5 0.7 1.9e-11 43.8 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFH43268.1 - 1.2e-16 60.5 3.1 1.5e-12 47.4 0.0 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Sec39 PF08314.6 KFH43269.1 - 6.4e-184 612.8 0.1 7.4e-184 612.6 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 ABC_membrane PF00664.18 KFH43270.1 - 1.3e-41 142.8 12.3 1.8e-41 142.3 8.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KFH43270.1 - 2.5e-34 118.5 0.2 1.2e-33 116.3 0.0 2.1 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 KFH43270.1 - 2.1e-05 23.8 0.1 0.0005 19.3 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KFH43270.1 - 2.9e-05 24.1 1.6 7.1e-05 22.8 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 KFH43270.1 - 0.00023 21.2 0.5 0.57 10.0 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KFH43270.1 - 0.0021 18.8 0.0 0.0051 17.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KFH43270.1 - 0.0039 17.3 0.3 0.021 14.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KFH43270.1 - 0.0071 16.5 0.1 0.11 12.7 0.1 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 KFH43270.1 - 0.008 15.6 0.0 0.02 14.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.4 KFH43270.1 - 0.013 14.0 0.1 0.025 13.1 0.0 1.4 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_25 PF13481.1 KFH43270.1 - 0.019 14.4 0.5 0.11 11.8 0.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KFH43270.1 - 0.019 14.6 0.6 0.062 13.0 0.0 2.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 KFH43270.1 - 0.029 14.2 1.2 0.22 11.4 0.8 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 KFH43270.1 - 0.056 12.8 0.7 0.5 9.7 0.2 2.2 2 0 0 2 2 2 0 AAA-like domain IstB_IS21 PF01695.12 KFH43270.1 - 0.058 12.8 0.1 0.68 9.3 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein bPH_5 PF10882.3 KFH43270.1 - 0.14 11.9 0.1 0.96 9.2 0.0 2.4 2 0 0 2 2 2 0 Bacterial PH domain Ribosomal_L11_N PF03946.9 KFH43271.1 - 4e-18 64.6 0.1 6.3e-18 63.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 KFH43271.1 - 9.8e-12 44.8 0.3 1.6e-11 44.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain ATP_bind_3 PF01171.15 KFH43271.1 - 0.095 12.1 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 PP-loop family Sec7 PF01369.15 KFH43272.1 - 6.5e-38 130.3 0.0 1.1e-37 129.5 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 KFH43272.1 - 0.00013 22.0 0.0 0.00029 20.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KFH43272.1 - 0.00018 21.6 0.0 0.00059 19.9 0.0 2.0 1 0 0 1 1 1 1 PH domain Glyco_transf_8 PF01501.15 KFH43273.1 - 1.6e-38 132.4 0.0 3.1e-38 131.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 KFH43273.1 - 0.0012 18.3 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative RRM_1 PF00076.17 KFH43274.1 - 7.9e-21 73.4 0.0 1.1e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH43274.1 - 1.3e-16 60.3 0.0 1.8e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH43274.1 - 1.6e-11 43.8 0.0 2.2e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hydrolase_4 PF12146.3 KFH43275.1 - 2.9e-22 78.3 0.0 7.7e-21 73.7 0.0 2.4 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 KFH43275.1 - 2.6e-17 63.4 0.1 3.3e-17 63.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH43275.1 - 4.4e-17 62.1 0.0 6.2e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFH43275.1 - 0.00081 19.0 0.0 0.0015 18.1 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFH43275.1 - 0.0023 17.1 0.5 1.2 8.2 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 KFH43275.1 - 0.06 12.2 0.0 0.15 10.8 0.0 1.6 1 1 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.20 KFH43275.1 - 0.07 12.7 0.0 0.46 10.0 0.0 2.0 2 0 0 2 2 2 0 Lipase (class 3) DUF1749 PF08538.5 KFH43275.1 - 0.11 11.4 0.0 0.5 9.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) DUF4355 PF14265.1 KFH43276.1 - 0.31 11.0 4.8 2.2 8.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) LMP PF04778.7 KFH43276.1 - 0.37 10.5 3.6 0.17 11.5 0.8 1.6 2 0 0 2 2 2 0 LMP repeated region MAPEG PF01124.13 KFH43277.1 - 5e-25 87.5 2.9 5.7e-25 87.4 2.0 1.0 1 0 0 1 1 1 1 MAPEG family Acetyltransf_1 PF00583.19 KFH43278.1 - 9.2e-17 60.8 0.0 1.2e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFH43278.1 - 2e-07 31.0 0.1 4.1e-07 30.0 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFH43278.1 - 1.5e-06 28.3 0.0 2e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFH43278.1 - 7.3e-06 25.6 0.0 1.2e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 KFH43278.1 - 4.7e-05 23.3 0.0 6e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFH43278.1 - 0.00017 21.4 0.0 0.00033 20.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Clathrin_lg_ch PF01086.12 KFH43279.1 - 8.3e-71 238.4 5.3 9.3e-71 238.3 3.7 1.0 1 0 0 1 1 1 1 Clathrin light chain DUF1444 PF07285.6 KFH43279.1 - 0.0064 15.8 1.3 0.009 15.3 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1444) HisK_N PF09385.5 KFH43279.1 - 0.045 13.3 0.6 0.072 12.6 0.4 1.3 1 0 0 1 1 1 0 Histidine kinase N terminal Bcl-2 PF00452.14 KFH43279.1 - 0.096 12.8 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Apoptosis regulator proteins, Bcl-2 family DUF4407 PF14362.1 KFH43279.1 - 0.17 10.7 4.1 0.092 11.6 0.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Toxin_trans PF07952.7 KFH43279.1 - 0.18 10.6 1.7 0.24 10.2 1.2 1.1 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain ATP-synt_B PF00430.13 KFH43279.1 - 0.39 10.5 7.5 0.74 9.6 5.2 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) zf-rbx1 PF12678.2 KFH43281.1 - 2.3e-11 43.6 1.4 4.2e-11 42.7 1.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KFH43281.1 - 2.5e-11 43.1 4.0 4.6e-11 42.3 2.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFH43281.1 - 3.6e-07 29.7 6.4 4.9e-06 26.1 4.8 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFH43281.1 - 2.8e-06 26.8 2.3 5.1e-06 26.0 1.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFH43281.1 - 7.8e-06 25.5 1.5 1.6e-05 24.5 1.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFH43281.1 - 2.6e-05 24.1 3.6 0.00011 22.1 2.5 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFH43281.1 - 0.0011 18.7 0.6 0.0024 17.6 0.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KFH43281.1 - 0.0012 18.4 2.0 0.0036 16.9 1.4 1.9 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.1 KFH43281.1 - 0.03 13.8 0.3 0.061 12.8 0.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 ATP-synt_C PF00137.16 KFH43281.1 - 0.036 13.9 0.0 4 7.4 0.0 3.2 3 0 0 3 3 3 0 ATP synthase subunit C zf-C3HC4_4 PF15227.1 KFH43281.1 - 0.037 13.8 1.0 0.086 12.7 0.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KFH43281.1 - 0.1 12.2 2.8 0.081 12.5 0.4 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain TMP-TENI PF02581.12 KFH43281.1 - 0.16 11.0 1.4 0.3 10.1 0.9 1.3 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI FANCL_C PF11793.3 KFH43281.1 - 0.83 9.6 2.8 4.3 7.3 2.0 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain FCH PF00611.18 KFH43282.1 - 0.048 13.8 0.1 0.098 12.8 0.1 1.6 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain STAG PF08514.6 KFH43283.1 - 0.063 12.9 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 STAG domain CTD_bind PF04818.8 KFH43284.1 - 4.2e-20 71.7 0.6 8.4e-20 70.7 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CTK3 PF12243.3 KFH43284.1 - 0.026 14.1 0.0 0.061 12.9 0.0 1.7 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 DUF3277 PF11681.3 KFH43284.1 - 0.037 13.4 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) DIT1_PvcA PF05141.7 KFH43285.1 - 0.031 13.5 0.1 0.037 13.3 0.0 1.0 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein HAUS6_N PF14661.1 KFH43285.1 - 0.068 12.5 0.1 0.077 12.3 0.1 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus CENP-H PF05837.7 KFH43285.1 - 0.097 12.8 0.3 0.12 12.5 0.2 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) EF-hand_1 PF00036.27 KFH43286.1 - 3.8e-41 135.2 12.8 1.2e-09 36.7 0.6 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KFH43286.1 - 3.3e-36 123.2 6.5 7.2e-20 70.8 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KFH43286.1 - 9.7e-35 117.9 12.4 7.6e-16 57.4 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 KFH43286.1 - 1.5e-30 102.2 8.0 1.3e-09 37.1 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KFH43286.1 - 6.9e-26 88.4 9.7 1.5e-06 27.2 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 KFH43286.1 - 1.6e-15 56.7 0.3 2.4e-08 33.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KFH43286.1 - 4.1e-09 36.1 2.5 0.0007 19.3 0.1 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KFH43286.1 - 1.6e-08 34.5 0.1 0.0043 17.0 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 KFH43286.1 - 4.1e-08 32.7 0.1 0.024 14.2 0.0 3.2 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 KFH43286.1 - 5.5e-07 29.4 2.2 5.1e-06 26.3 0.2 2.4 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 KFH43286.1 - 0.00017 21.3 0.5 0.33 10.6 0.0 2.4 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 KFH43286.1 - 0.00029 20.4 0.2 0.083 12.4 0.0 2.7 1 1 1 3 3 3 1 Caleosin related protein Tenui_NCP PF04876.7 KFH43286.1 - 0.0026 17.3 0.1 0.14 11.7 0.0 2.3 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 KFH43286.1 - 0.003 17.5 0.7 1.4 8.9 0.0 2.6 3 0 0 3 3 3 2 RNA polymerase Rpb4 Toprim_2 PF13155.1 KFH43286.1 - 0.0075 16.5 1.4 2.1 8.7 0.0 2.5 1 1 1 2 2 2 2 Toprim-like DUF3349 PF11829.3 KFH43286.1 - 0.018 15.4 0.4 9.3 6.7 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) EF-hand_10 PF14788.1 KFH43286.1 - 0.27 10.9 3.2 0.91 9.2 0.1 3.2 1 1 3 4 4 4 0 EF hand RloB PF13707.1 KFH43286.1 - 0.31 10.6 4.1 1 8.9 1.0 2.3 1 1 1 2 2 2 0 RloB-like protein PB1 PF00564.19 KFH43286.1 - 0.47 10.1 2.5 36 4.1 0.0 3.3 2 1 1 3 3 3 0 PB1 domain CorA PF01544.13 KFH43287.1 - 5e-15 55.2 0.3 9.2e-15 54.4 0.2 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein POP1 PF06978.6 KFH43288.1 - 2.9e-61 206.4 8.9 2.9e-61 206.4 6.2 2.1 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 KFH43288.1 - 1.3e-29 101.8 0.0 5.2e-29 99.9 0.0 2.1 1 0 0 1 1 1 1 POPLD (NUC188) domain MFS_1 PF07690.11 KFH43289.1 - 2.1e-42 145.1 42.9 5.5e-40 137.1 20.5 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH43289.1 - 6.8e-17 61.1 6.4 6.8e-17 61.1 4.5 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KFH43289.1 - 3.6e-07 28.7 6.6 5.1e-07 28.2 4.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 KFH43289.1 - 0.0039 15.3 10.3 0.031 12.3 3.7 2.8 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Acatn PF13000.2 KFH43290.1 - 1e-151 506.2 20.1 1.9e-78 264.3 6.1 3.0 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 Yip1 PF04893.12 KFH43291.1 - 0.0034 16.8 0.4 0.0047 16.4 0.3 1.1 1 0 0 1 1 1 1 Yip1 domain 7tm_1 PF00001.16 KFH43291.1 - 0.0044 16.1 0.0 0.0055 15.8 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4199 PF13858.1 KFH43291.1 - 0.024 14.5 0.1 0.035 14.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) PepSY_TM_2 PF13703.1 KFH43291.1 - 0.87 9.8 4.4 1.9 8.7 3.0 1.6 1 1 0 1 1 1 0 PepSY-associated TM helix MFS_1 PF07690.11 KFH43293.1 - 2.3e-43 148.2 65.6 8.4e-39 133.2 29.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFH43293.1 - 1.6e-08 33.4 9.4 1.6e-08 33.4 6.5 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 KFH43293.1 - 8.5e-05 21.3 39.5 0.00014 20.5 7.4 3.1 2 1 0 3 3 3 2 Sugar (and other) transporter GATA PF00320.22 KFH43294.1 - 1.6e-16 59.3 1.9 3.3e-16 58.3 1.3 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 KFH43294.1 - 2.6e-12 46.0 0.2 4.7e-12 45.2 0.2 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) IDH PF03971.9 KFH43294.1 - 0.0099 14.2 0.0 0.014 13.7 0.0 1.1 1 0 0 1 1 1 1 Monomeric isocitrate dehydrogenase Histone_HNS PF00816.16 KFH43295.1 - 0.018 15.5 1.1 0.039 14.4 0.1 2.0 2 0 0 2 2 2 0 H-NS histone family Pyrid_oxidase_2 PF13883.1 KFH43296.1 - 8.3e-38 129.8 0.0 4.7e-36 124.1 0.0 2.1 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase BRCT PF00533.21 KFH43297.1 - 1.2e-11 44.5 0.0 2.4e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KFH43297.1 - 1.6e-11 43.9 0.0 3.2e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain fn3 PF00041.16 KFH43297.1 - 0.0033 17.5 0.0 0.012 15.7 0.0 2.0 1 1 0 1 1 1 1 Fibronectin type III domain Mitofilin PF09731.4 KFH43297.1 - 0.78 8.3 23.8 1 7.9 16.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SEN1_N PF12726.2 KFH43300.1 - 7.4e-126 421.0 0.3 9.5e-126 420.6 0.2 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 KFH43300.1 - 1.4e-70 237.5 0.2 1.4e-70 237.5 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.1 KFH43300.1 - 9.7e-64 214.4 0.0 1.8e-63 213.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFH43300.1 - 6e-12 45.1 0.6 3.5e-11 42.6 0.2 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KFH43300.1 - 9e-08 31.9 1.1 5.3e-05 22.8 0.1 3.3 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.13 KFH43300.1 - 0.00019 21.0 0.2 0.19 11.2 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 KFH43300.1 - 0.004 16.6 2.6 1.1 8.7 0.0 4.0 4 0 0 4 4 4 1 DEAD/DEAH box helicase AAA_25 PF13481.1 KFH43300.1 - 0.024 14.0 0.2 0.063 12.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KFH43300.1 - 0.028 14.5 0.1 1.4 9.1 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 KFH43300.1 - 2.6 8.3 9.0 0.94 9.7 0.8 2.9 2 1 0 2 2 2 0 AAA domain AAA_12 PF13087.1 KFH43301.1 - 2.9e-24 85.5 0.1 5.6e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KFH43301.1 - 6e-10 39.1 0.0 1.5e-09 37.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KFH43301.1 - 1.5e-08 34.4 0.0 8.1e-07 28.7 0.0 2.7 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 KFH43301.1 - 9.2e-08 32.1 0.1 2.1e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.1 KFH43301.1 - 0.0054 16.3 0.0 2.9 7.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 KFH43301.1 - 0.11 12.2 0.0 0.73 9.6 0.0 2.1 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Med12 PF09497.5 KFH43302.1 - 1.5e-27 95.3 0.7 2.2e-26 91.6 0.2 2.5 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.3 KFH43302.1 - 6.8e-06 24.8 0.4 0.0083 14.6 0.0 2.3 1 1 0 2 2 2 2 Eukaryotic Mediator 12 subunit domain Yae1_N PF09811.4 KFH43303.1 - 3.2e-13 48.9 4.0 5.8e-13 48.1 2.5 1.7 1 1 1 2 2 2 1 Essential protein Yae1, N terminal Sulfate_tra_GLY PF13792.1 KFH43306.1 - 0.006 16.2 3.9 0.0071 15.9 2.7 1.1 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif Phage_holin_1 PF04531.8 KFH43306.1 - 0.04 13.9 0.6 0.044 13.8 0.4 1.1 1 0 0 1 1 1 0 Bacteriophage holin Phageshock_PspG PF09583.5 KFH43306.1 - 0.27 11.3 5.2 0.33 11.0 3.6 1.2 1 0 0 1 1 1 0 Phage shock protein G (Phageshock_PspG) Glycoprotein_B PF00606.13 KFH43306.1 - 3.1 5.7 5.3 3 5.7 3.7 1.0 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B NT-C2 PF10358.4 KFH43307.1 - 2.5e-25 88.6 0.0 3.9e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Zip PF02535.17 KFH43307.1 - 0.015 14.3 1.1 0.02 13.9 0.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Macoilin PF09726.4 KFH43307.1 - 0.91 7.7 2.0 1.2 7.2 1.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Lyase_1 PF00206.15 KFH43308.1 - 3.4e-108 361.5 0.0 5e-108 360.9 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 KFH43308.1 - 4e-21 74.8 0.0 9.2e-21 73.6 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus BAF1_ABF1 PF04684.8 KFH43308.1 - 1.7 7.3 3.9 3 6.6 2.7 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor GFA PF04828.9 KFH43309.1 - 1.5e-15 56.8 1.7 2e-15 56.5 1.2 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DFP PF04127.10 KFH43310.1 - 2.2e-11 43.6 0.0 0.00011 21.8 0.0 3.2 3 0 0 3 3 3 3 DNA / pantothenate metabolism flavoprotein Menin PF05053.8 KFH43310.1 - 0.054 11.6 10.6 0.073 11.2 7.4 1.1 1 0 0 1 1 1 0 Menin LMBR1 PF04791.11 KFH43310.1 - 0.17 10.4 0.3 0.21 10.1 0.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Raftlin PF15250.1 KFH43310.1 - 5.6 5.3 7.5 8 4.8 5.2 1.1 1 0 0 1 1 1 0 Raftlin CENP-O PF09496.5 KFH43311.1 - 7.3e-21 74.2 0.0 1.6e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component DivIVA PF05103.8 KFH43311.1 - 0.024 14.7 0.4 0.047 13.7 0.3 1.6 1 0 0 1 1 1 0 DivIVA protein Thymidylat_synt PF00303.14 KFH43311.1 - 0.038 12.9 0.2 0.061 12.3 0.2 1.3 1 0 0 1 1 1 0 Thymidylate synthase DUF4140 PF13600.1 KFH43311.1 - 0.099 13.0 5.1 4.1 7.9 0.8 3.4 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) bZIP_2 PF07716.10 KFH43311.1 - 0.16 11.8 1.1 0.49 10.2 0.8 1.9 1 0 0 1 1 1 0 Basic region leucine zipper Lipase_2 PF01674.13 KFH43312.1 - 2.6e-09 36.7 0.0 3.9e-09 36.1 0.0 1.5 1 1 0 1 1 1 1 Lipase (class 2) Abhydrolase_5 PF12695.2 KFH43312.1 - 1e-05 25.2 0.2 1.7e-05 24.5 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFH43312.1 - 1.2e-05 25.3 0.1 1.5e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 KFH43312.1 - 0.0005 19.2 0.0 0.03 13.4 0.0 2.8 2 1 2 4 4 4 1 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.8 KFH43312.1 - 0.00066 19.3 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 KFH43312.1 - 0.0011 18.3 0.1 0.0021 17.3 0.1 1.4 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.15 KFH43312.1 - 0.0015 18.0 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.7 KFH43312.1 - 0.0045 16.3 0.0 0.0093 15.3 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_2 PF02230.11 KFH43312.1 - 0.019 14.4 0.0 2.1 7.7 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF2974 PF11187.3 KFH43312.1 - 0.038 13.3 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Thioesterase PF00975.15 KFH43312.1 - 0.12 12.5 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain zf-C2H2 PF00096.21 KFH43313.1 - 2.1e-08 34.0 20.8 0.0021 18.3 1.5 4.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFH43313.1 - 5.3e-06 26.3 26.6 0.00076 19.6 0.9 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger Wbp11 PF09429.5 KFH43314.1 - 4.3e-23 81.0 13.0 4.3e-23 81.0 9.0 2.6 2 1 1 3 3 3 1 WW domain binding protein 11 DUF2294 PF10057.4 KFH43314.1 - 0.0097 15.5 0.1 0.016 14.8 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2294) CCDC84 PF14968.1 KFH43314.1 - 0.24 10.8 2.3 1.3 8.5 0.5 2.1 2 0 0 2 2 2 0 Coiled coil protein 84 Lipoprotein_7 PF01540.11 KFH43314.1 - 2.3 7.2 10.6 0.053 12.5 2.5 1.6 2 0 0 2 2 2 0 Adhesin lipoprotein eIF-1a PF01176.14 KFH43315.1 - 1.7e-26 91.3 0.1 2.5e-26 90.8 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 IBR PF01485.16 KFH43316.1 - 7.8e-14 51.3 28.9 3.1e-07 30.1 4.2 3.6 3 0 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 KFH43316.1 - 0.00068 19.4 1.9 0.00068 19.4 1.3 3.3 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 KFH43316.1 - 0.0028 17.2 2.3 0.0028 17.2 1.6 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF4446 PF14584.1 KFH43316.1 - 4.4 7.1 16.5 1.4 8.7 1.5 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF4446) Pkinase PF00069.20 KFH43317.1 - 3.9e-58 196.6 0.0 2.8e-57 193.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH43317.1 - 9.4e-29 100.2 0.1 4.6e-20 71.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 KFH43317.1 - 1.4e-07 31.9 0.4 4.1e-07 30.4 0.3 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KFH43317.1 - 0.0003 19.8 0.4 0.0015 17.5 0.0 2.1 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 KFH43317.1 - 0.006 16.3 0.6 0.12 12.0 0.0 3.0 3 1 0 4 4 4 1 Phosphotransferase enzyme family Polysacc_lyase PF14099.1 KFH43318.1 - 3.4e-48 164.2 6.3 4.1e-48 163.9 4.4 1.0 1 0 0 1 1 1 1 Polysaccharide lyase adh_short PF00106.20 KFH43319.1 - 7.5e-08 32.4 0.0 3.8e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 KFH43319.1 - 0.00079 19.1 0.3 0.0026 17.4 0.0 1.8 2 0 0 2 2 2 1 KR domain Mito_fiss_reg PF05308.6 KFH43319.1 - 2.6 7.3 5.0 4.3 6.6 3.5 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 KFH43319.1 - 3.3 6.9 6.7 5.6 6.1 4.7 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RhoGAP PF00620.22 KFH43322.1 - 8e-47 158.6 0.1 2.4e-46 157.1 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 KFH43322.1 - 1.6e-13 50.6 1.4 2.2e-13 50.1 0.0 1.9 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DED PF01335.16 KFH43322.1 - 0.048 13.7 0.1 0.13 12.4 0.1 1.7 1 0 0 1 1 1 0 Death effector domain ERM PF00769.14 KFH43322.1 - 1.3 8.4 13.9 2.8 7.4 9.7 1.6 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DNA_methylase PF00145.12 KFH43323.1 - 2.7e-35 122.1 0.0 1.2e-26 93.6 0.0 2.2 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase DUF3328 PF11807.3 KFH43324.1 - 0.11 12.1 0.9 7.3 6.1 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) EAF PF09816.4 KFH43325.1 - 2.2e-17 62.9 0.0 5.9e-17 61.5 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor DUF4185 PF13810.1 KFH43326.1 - 5.4e-76 255.5 1.5 6.1e-76 255.3 1.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) WH1 PF00568.18 KFH43328.1 - 4.8e-26 90.6 0.2 6.6e-26 90.2 0.1 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 KFH43328.1 - 0.00023 20.6 0.2 0.00054 19.4 0.2 1.6 1 0 0 1 1 1 1 WH2 motif ERCC4 PF02732.10 KFH43329.1 - 9.6e-25 87.0 0.0 2.6e-24 85.5 0.0 1.8 1 0 0 1 1 1 1 ERCC4 domain HHH_2 PF12826.2 KFH43329.1 - 0.026 14.4 0.1 0.094 12.6 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif HHH_5 PF14520.1 KFH43329.1 - 0.088 12.9 0.0 0.27 11.4 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain HSP70 PF00012.15 KFH43330.1 - 9.9e-78 261.5 0.9 1.4e-77 261.0 0.6 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFH43330.1 - 1.1e-06 27.5 0.2 1.9e-06 26.7 0.1 1.4 1 1 0 1 1 1 1 MreB/Mbl protein JAB PF01398.16 KFH43332.1 - 4.6e-35 119.7 0.0 8.2e-35 118.9 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KFH43332.1 - 5.9e-25 87.5 3.1 6e-25 87.5 0.9 1.9 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 KFH43332.1 - 7.6e-08 31.8 0.0 1.3e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Fork_head PF00250.13 KFH43333.1 - 5e-17 61.7 0.0 5.5e-15 55.1 0.0 2.7 2 0 0 2 2 2 2 Fork head domain RNA_pol_Rpc34 PF05158.7 KFH43334.1 - 8.5e-95 317.6 0.0 1.1e-94 317.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.6 KFH43334.1 - 0.0015 18.8 0.6 0.056 13.8 0.0 3.1 3 1 0 3 3 3 1 Replication protein A C terminal ENTH PF01417.15 KFH43335.1 - 1.1e-46 157.8 0.1 1.5e-46 157.2 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 KFH43335.1 - 0.00085 18.1 0.0 0.0012 17.6 0.0 1.1 1 0 0 1 1 1 1 ANTH domain Cactin_mid PF10312.4 KFH43337.1 - 2.9e-59 199.5 6.4 4e-59 199.0 4.5 1.2 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 KFH43337.1 - 9.2e-50 167.4 1.8 1.6e-49 166.6 1.3 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein DUF1087 PF06465.8 KFH43337.1 - 0.032 14.1 0.1 0.095 12.6 0.1 1.9 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) Gal4_dimer PF03902.8 KFH43337.1 - 0.13 12.2 0.3 1 9.3 0.0 2.5 2 0 0 2 2 2 0 Gal4-like dimerisation domain DUF2404 PF10296.4 KFH43338.1 - 0.0022 18.0 0.0 0.018 15.1 0.0 2.1 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Glyco_hydro_35 PF01301.14 KFH43340.1 - 8.9e-88 294.6 0.1 1.2e-87 294.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 KFH43340.1 - 5.8e-51 171.4 0.0 5.3e-27 94.2 0.0 2.6 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 KFH43340.1 - 4.4e-49 166.3 1.3 7.3e-49 165.6 0.9 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 KFH43340.1 - 4.6e-21 74.0 0.0 1.1e-20 72.8 0.0 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cep57_CLD_2 PF14197.1 KFH43341.1 - 3e-31 107.1 69.7 2.2e-16 59.5 9.3 6.9 4 2 2 6 6 6 4 Centrosome localisation domain of PPC89 Cep57_MT_bd PF06657.8 KFH43341.1 - 1.3e-26 92.3 0.4 1.3e-26 92.3 0.3 5.8 5 1 0 5 5 5 1 Centrosome microtubule-binding domain of Cep57 HALZ PF02183.13 KFH43341.1 - 4.1e-05 23.1 58.3 0.0042 16.7 2.5 9.5 6 1 4 10 10 10 5 Homeobox associated leucine zipper WEMBL PF05701.6 KFH43341.1 - 0.00085 17.9 40.9 0.00085 17.9 28.4 2.0 3 0 0 3 3 3 1 Weak chloroplast movement under blue light CCDC155 PF14662.1 KFH43341.1 - 0.0017 18.0 60.2 0.0031 17.1 17.1 5.3 2 1 2 4 4 4 2 Coiled-coil region of CCDC155 APG6 PF04111.7 KFH43341.1 - 0.0056 15.7 10.1 0.0056 15.7 7.0 5.2 4 1 2 6 6 6 2 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 KFH43341.1 - 0.0092 15.7 4.3 0.0092 15.7 3.0 6.7 4 1 4 8 8 8 4 TPR/MLP1/MLP2-like protein Noc2 PF03715.8 KFH43343.1 - 1.2e-116 388.8 0.0 2.4e-116 387.7 0.0 1.6 1 0 0 1 1 1 1 Noc2p family DUF4050 PF13259.1 KFH43343.1 - 0.055 13.3 2.1 0.14 12.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) Cwf_Cwc_15 PF04889.7 KFH43343.1 - 0.67 9.6 42.4 0.12 12.0 5.3 3.3 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein Glyco_hydro_3 PF00933.16 KFH43344.1 - 1.7e-85 286.6 0.0 2.4e-85 286.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KFH43344.1 - 1e-68 231.2 0.2 3.6e-67 226.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KFH43344.1 - 2.9e-23 81.6 0.0 5.9e-23 80.5 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 KFH43344.1 - 3e-19 69.1 0.0 5.4e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Metallophos PF00149.23 KFH43345.1 - 8e-12 44.9 5.2 6.1e-11 42.0 3.6 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_S30 PF04758.9 KFH43346.1 - 2.1e-28 97.8 4.8 2.6e-28 97.5 3.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 XLF PF09302.6 KFH43347.1 - 4.4e-29 101.4 0.0 6.6e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 XLF (XRCC4-like factor) Pkinase PF00069.20 KFH43348.1 - 1e-71 241.1 0.0 1.6e-71 240.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH43348.1 - 1.4e-36 125.9 0.0 2.6e-36 125.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH43348.1 - 5.1e-05 22.3 0.1 0.14 11.1 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pox_ser-thr_kin PF05445.6 KFH43348.1 - 0.14 10.9 0.2 0.21 10.3 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF4095 PF13338.1 KFH43349.1 - 0.012 15.7 1.3 0.091 12.9 0.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4095) Hist_deacetyl PF00850.14 KFH43350.1 - 1.6e-71 241.2 0.1 2.7e-71 240.4 0.1 1.4 1 0 0 1 1 1 1 Histone deacetylase domain Pro_isomerase PF00160.16 KFH43351.1 - 1e-40 139.4 0.5 1.3e-40 139.1 0.4 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MARVEL PF01284.18 KFH43352.1 - 7.1e-07 29.1 8.3 1.6e-06 27.9 5.8 1.5 1 1 0 1 1 1 1 Membrane-associating domain DUF3021 PF11457.3 KFH43352.1 - 0.39 10.5 8.1 0.02 14.7 2.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) RDD PF06271.7 KFH43352.1 - 1.8 8.4 5.8 10 6.0 0.1 2.2 1 1 1 2 2 2 0 RDD family CbiQ PF02361.11 KFH43352.1 - 4.7 6.7 7.4 11 5.5 0.5 2.2 1 1 0 2 2 2 0 Cobalt transport protein Cupin_1 PF00190.17 KFH43353.1 - 8.5e-31 106.3 0.0 1.9e-14 53.2 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 KFH43353.1 - 8.5e-27 92.4 0.8 2.1e-12 46.3 0.2 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KFH43353.1 - 3.1e-09 36.0 0.0 0.00089 18.5 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 KFH43353.1 - 1.5e-07 31.1 0.2 0.00089 18.9 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain MannoseP_isomer PF01050.13 KFH43353.1 - 0.0017 17.9 0.0 0.39 10.3 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase ARD PF03079.9 KFH43353.1 - 0.012 15.5 0.3 0.96 9.3 0.0 2.3 2 0 0 2 2 2 0 ARD/ARD' family 3-HAO PF06052.7 KFH43353.1 - 0.043 13.2 0.0 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase Cupin_7 PF12973.2 KFH43353.1 - 0.097 12.5 0.0 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 ChrR Cupin-like domain PIP5K PF01504.13 KFH43354.1 - 4.8e-57 192.9 0.0 9.3e-57 192.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 KFH43354.1 - 6.1e-26 91.0 0.0 1e-25 90.3 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 KFH43354.1 - 6.1e-14 51.6 9.4 6.1e-14 51.6 6.5 2.0 2 0 0 2 2 2 1 FYVE zinc finger Fungal_trans_2 PF11951.3 KFH43355.1 - 1.2e-47 162.4 0.0 1.5e-47 162.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH43355.1 - 3.6e-06 26.7 8.2 3.6e-06 26.7 5.7 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BolA PF01722.13 KFH43356.1 - 1.7e-27 95.1 0.2 2.5e-27 94.6 0.1 1.2 1 0 0 1 1 1 1 BolA-like protein VPS28 PF03997.7 KFH43358.1 - 1e-55 188.2 1.0 1.2e-55 188.0 0.7 1.1 1 0 0 1 1 1 1 VPS28 protein GvpG PF05120.7 KFH43358.1 - 0.48 10.2 8.1 0.43 10.4 0.2 2.4 2 0 0 2 2 2 0 Gas vesicle protein G Cellulase PF00150.13 KFH43360.1 - 2.5e-16 59.7 0.1 3.1e-16 59.4 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 KFH43360.1 - 0.00089 18.4 0.9 0.0016 17.6 0.0 1.8 2 0 0 2 2 2 1 Beta-galactosidase DUF1275 PF06912.6 KFH43361.1 - 4.6e-37 127.2 13.5 5.5e-37 126.9 9.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) PIG-P PF08510.7 KFH43361.1 - 2.7 7.6 4.9 24 4.5 0.7 2.5 2 0 0 2 2 2 0 PIG-P IF4E PF01652.13 KFH43364.1 - 4.5e-60 201.9 0.1 5.6e-60 201.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E APC_CDC26 PF10471.4 KFH43365.1 - 9.3e-12 45.5 5.6 9.3e-12 45.5 3.8 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex APC subunit 1 Ribosomal_60s PF00428.14 KFH43365.1 - 0.25 11.7 5.7 0.32 11.4 3.9 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein Tad PF13400.1 KFH43365.1 - 0.39 10.7 4.4 0.74 9.8 3.1 1.5 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like FLO_LFY PF01698.11 KFH43365.1 - 1 8.1 8.3 1.1 7.9 5.8 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Chorion_2 PF03964.10 KFH43365.1 - 1.8 9.1 7.3 2.6 8.6 5.1 1.2 1 0 0 1 1 1 0 Chorion family 2 Suf PF05843.9 KFH43365.1 - 5.7 6.5 6.9 6 6.4 4.8 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RRM_1 PF00076.17 KFH43366.1 - 2.6e-14 52.6 0.0 4.1e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH43366.1 - 4.7e-11 42.5 0.0 7.1e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH43366.1 - 2e-08 33.9 0.0 2.9e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 KFH43367.1 - 1.5e-35 122.6 0.0 2.1e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH43367.1 - 7.7e-18 64.4 0.0 2e-17 63.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH43367.1 - 3.9e-06 26.0 0.0 8.4e-06 24.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KFH43367.1 - 0.0026 17.5 0.5 0.015 15.0 0.2 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KFH43367.1 - 0.033 13.2 0.0 0.066 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AMP-binding PF00501.23 KFH43369.1 - 1.4e-68 231.2 0.0 2.5e-68 230.4 0.0 1.3 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFH43369.1 - 3e-12 47.3 0.2 3e-12 47.3 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain L27 PF02828.11 KFH43370.1 - 0.046 13.4 0.9 0.084 12.5 0.1 1.9 2 0 0 2 2 2 0 L27 domain Cyt-b5 PF00173.23 KFH43371.1 - 5e-12 45.4 0.0 7.1e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Phage_P2_GpE PF06528.7 KFH43371.1 - 0.0033 16.8 2.0 0.0082 15.5 1.4 1.6 1 0 0 1 1 1 1 Phage P2 GpE SQS_PSY PF00494.14 KFH43371.1 - 0.014 14.7 0.1 0.029 13.6 0.1 1.5 2 0 0 2 2 2 0 Squalene/phytoene synthase NQR2_RnfD_RnfE PF03116.10 KFH43371.1 - 0.11 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 NQR2, RnfD, RnfE family Voltage_CLC PF00654.15 KFH43372.1 - 6.2e-90 301.7 29.0 1.1e-89 300.9 20.1 1.4 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.23 KFH43372.1 - 1e-11 44.4 0.1 2.4e-05 24.0 0.0 2.5 2 0 0 2 2 2 2 CBS domain Myb_DNA-bind_4 PF13837.1 KFH43373.1 - 0.12 12.5 0.1 1.2 9.2 0.0 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain BTB_2 PF02214.17 KFH43374.1 - 0.00015 21.8 0.1 0.0093 16.1 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain Ribosomal_L32p PF01783.18 KFH43375.1 - 6.4e-13 48.6 6.1 9.2e-13 48.1 4.2 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family ORC6 PF05460.8 KFH43376.1 - 0.0051 15.9 0.9 0.0065 15.6 0.6 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) PAP2 PF01569.16 KFH43377.1 - 1.3e-17 63.6 2.0 4.3e-17 62.0 1.4 1.9 1 0 0 1 1 1 1 PAP2 superfamily Pkinase PF00069.20 KFH43378.1 - 3.6e-23 82.0 0.0 5.8e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 KFH43378.1 - 5.2e-15 54.6 8.8 1.4e-07 31.1 0.0 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat HEAT PF02985.17 KFH43378.1 - 2.1e-10 39.8 6.0 0.14 12.3 0.0 6.7 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 KFH43378.1 - 5.6e-06 26.5 1.0 0.067 13.4 0.0 4.0 1 1 1 2 2 2 2 HEAT repeats Pkinase_Tyr PF07714.12 KFH43378.1 - 0.00019 20.5 0.0 0.00029 19.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH43378.1 - 0.0021 17.0 0.0 0.0043 16.0 0.0 1.5 1 1 0 1 1 1 1 Kinase-like HEAT_EZ PF13513.1 KFH43378.1 - 0.0032 17.9 5.0 0.12 12.9 0.1 4.1 4 1 1 5 5 5 1 HEAT-like repeat Adaptin_N PF01602.15 KFH43378.1 - 0.023 13.0 0.1 1.2 7.4 0.0 2.1 2 0 0 2 2 2 0 Adaptin N terminal region ThiF PF00899.16 KFH43379.1 - 7.5e-41 139.1 0.2 1.5e-40 138.1 0.1 1.5 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 KFH43379.1 - 3.3e-30 103.4 0.3 9.1e-30 102.0 0.2 1.8 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 KFH43379.1 - 4.3e-23 81.2 0.9 1.5e-21 76.2 0.1 2.5 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.4 KFH43379.1 - 9.8e-21 72.8 1.0 2.8e-20 71.4 0.7 1.9 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.1 KFH43379.1 - 0.0005 20.2 0.1 0.0017 18.5 0.0 1.9 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 KFH43379.1 - 0.00072 19.6 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Glyco_hydro_76 PF03663.9 KFH43380.1 - 1.8e-142 475.1 2.3 2.3e-142 474.7 1.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 CBFD_NFYB_HMF PF00808.18 KFH43381.1 - 1.1e-08 35.0 0.2 1.9e-08 34.2 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone EMP70 PF02990.11 KFH43382.1 - 2.8e-165 550.7 0.0 5e-165 549.9 0.0 1.4 1 1 0 1 1 1 1 Endomembrane protein 70 MFS_1 PF07690.11 KFH43382.1 - 8.1e-06 24.7 5.1 8.1e-06 24.7 3.5 2.7 1 1 0 2 2 2 1 Major Facilitator Superfamily MecA_N PF05223.6 KFH43382.1 - 0.074 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 NTF2-like N-terminal transpeptidase domain DUF3267 PF11667.3 KFH43382.1 - 1.9 8.7 15.2 0.092 12.9 0.6 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3267) adh_short PF00106.20 KFH43383.1 - 1.2e-29 103.3 0.5 2e-29 102.6 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH43383.1 - 1.9e-28 99.8 0.1 2.4e-28 99.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH43383.1 - 7.7e-12 45.2 0.3 1.2e-11 44.5 0.2 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KFH43383.1 - 0.00016 21.3 0.0 0.00037 20.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 KFH43383.1 - 0.0092 15.0 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.5 KFH43383.1 - 0.035 13.2 0.0 0.055 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Peptidase_C58 PF03543.9 KFH43383.1 - 0.089 12.2 2.6 0.13 11.7 1.8 1.3 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen OTCace PF00185.19 KFH43383.1 - 0.18 11.7 0.5 0.37 10.6 0.0 1.8 2 0 0 2 2 2 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 3HCDH_N PF02737.13 KFH43383.1 - 3.3 7.3 5.4 0.31 10.6 0.1 2.0 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_hydro_72 PF03198.9 KFH43384.1 - 2e-105 352.2 0.1 2.4e-105 351.9 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase FlgD_ig PF13860.1 KFH43384.1 - 0.079 12.7 0.5 1.8 8.3 0.4 2.5 2 0 0 2 2 2 0 FlgD Ig-like domain Fzo_mitofusin PF04799.8 KFH43386.1 - 0.043 13.2 0.3 0.043 13.2 0.2 4.2 3 1 0 4 4 4 0 fzo-like conserved region Reo_sigmaC PF04582.7 KFH43386.1 - 0.071 12.2 19.6 0.095 11.8 0.9 4.4 2 2 1 4 4 4 0 Reovirus sigma C capsid protein Beta-Casp PF10996.3 KFH43386.1 - 0.11 12.4 0.9 0.31 10.9 0.6 1.8 1 0 0 1 1 1 0 Beta-Casp domain Saccharop_dh_N PF04455.7 KFH43386.1 - 0.7 10.0 6.2 0.45 10.6 0.1 3.2 3 1 1 4 4 4 0 LOR/SDH bifunctional enzyme conserved region Guanylate_kin PF00625.16 KFH43387.1 - 2.9e-59 199.6 0.0 3.2e-59 199.4 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.1 KFH43387.1 - 1.2e-05 25.6 0.0 2.9e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFH43387.1 - 0.0001 23.0 0.0 0.00019 22.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFH43387.1 - 0.00025 20.9 0.1 0.0016 18.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KFH43387.1 - 0.0012 18.0 0.0 0.004 16.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KFH43387.1 - 0.002 18.1 0.0 0.0054 16.7 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFH43387.1 - 0.0021 18.1 0.0 0.01 16.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KFH43387.1 - 0.011 15.7 0.1 0.083 12.8 0.0 2.2 1 1 0 1 1 1 0 AAA domain DUF1895 PF08988.5 KFH43387.1 - 0.014 15.3 0.2 0.025 14.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1895) ADK PF00406.17 KFH43387.1 - 0.12 12.2 0.2 6 6.7 0.0 2.3 2 0 0 2 2 2 0 Adenylate kinase AAA_29 PF13555.1 KFH43387.1 - 0.14 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain DOCK-C2 PF14429.1 KFH43388.1 - 2.6e-21 76.0 0.0 4.6e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 KFH43388.1 - 4.1e-10 39.2 3.1 1.9e-09 37.0 0.0 2.8 3 0 0 3 3 3 1 Dedicator of cytokinesis SH3_1 PF00018.23 KFH43388.1 - 1.6e-05 24.1 0.0 3.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFH43388.1 - 0.00021 20.8 0.0 0.0012 18.4 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain Sigma70_ner PF04546.8 KFH43388.1 - 0.0017 18.0 4.7 0.0044 16.6 3.2 1.7 1 0 0 1 1 1 1 Sigma-70, non-essential region BSP_II PF05432.6 KFH43388.1 - 0.0025 17.1 7.6 0.0058 15.9 5.3 1.5 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Nucleoplasmin PF03066.10 KFH43388.1 - 0.0026 17.3 3.6 0.0053 16.2 2.5 1.5 1 0 0 1 1 1 1 Nucleoplasmin CENP-B_dimeris PF09026.5 KFH43388.1 - 0.0055 16.9 8.9 0.016 15.4 6.2 1.7 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Myc_N PF01056.13 KFH43388.1 - 0.019 14.1 6.7 0.038 13.1 4.7 1.4 1 0 0 1 1 1 0 Myc amino-terminal region SH3_2 PF07653.12 KFH43388.1 - 0.059 12.8 0.0 0.16 11.5 0.0 1.8 1 0 0 1 1 1 0 Variant SH3 domain FAM176 PF14851.1 KFH43388.1 - 0.11 12.1 7.3 0.29 10.8 5.0 1.6 1 0 0 1 1 1 0 FAM176 family RP-C_C PF11800.3 KFH43388.1 - 0.43 10.2 3.9 1.2 8.7 2.7 1.7 1 0 0 1 1 1 0 Replication protein C C-terminal region PBP1_TM PF14812.1 KFH43388.1 - 6.1 7.2 10.8 22 5.4 7.5 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WD40 PF00400.27 KFH43389.1 - 4.3e-26 89.7 13.4 4.1e-11 42.2 0.3 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KFH43389.1 - 0.00035 20.3 0.0 0.021 14.5 0.0 2.5 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 KFH43389.1 - 0.0028 16.4 0.0 1 8.0 0.0 2.8 1 1 3 4 4 4 3 Nup133 N terminal like Nup160 PF11715.3 KFH43389.1 - 0.0062 14.7 0.0 0.055 11.6 0.0 2.0 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Nbas_N PF15492.1 KFH43389.1 - 0.023 13.7 0.1 3.5 6.6 0.0 2.9 2 2 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal IceA2 PF05862.6 KFH43389.1 - 0.034 13.8 0.3 15 5.4 0.0 3.1 2 1 1 3 3 3 0 Helicobacter pylori IceA2 protein Hira PF07569.6 KFH43389.1 - 0.062 12.5 0.0 0.93 8.6 0.0 2.4 3 0 0 3 3 3 0 TUP1-like enhancer of split UFD1 PF03152.9 KFH43390.1 - 2e-67 225.7 0.0 2.5e-67 225.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 KFH43390.1 - 0.1 12.2 0.1 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 Bul1_N PF04425.7 KFH43391.1 - 7.8e-08 31.2 0.1 8.1e-06 24.6 0.1 2.6 1 1 1 2 2 2 1 Bul1 N terminus Bul1_C PF04426.7 KFH43391.1 - 6e-05 22.3 0.0 0.00037 19.7 0.0 1.9 2 0 0 2 2 2 1 Bul1 C terminus Mito_carr PF00153.22 KFH43392.1 - 1.3e-65 217.1 5.1 9.3e-24 82.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ATP-synt_C PF00137.16 KFH43393.1 - 7.7e-27 92.9 26.2 7.5e-16 57.7 6.1 2.4 2 0 0 2 2 2 2 ATP synthase subunit C Oxidored_q2 PF00420.19 KFH43393.1 - 3.8 7.1 10.4 3.9 7.1 4.0 2.9 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L EamA PF00892.15 KFH43394.1 - 0.00025 21.0 8.7 0.00025 21.0 6.0 1.7 1 1 1 2 2 2 1 EamA-like transporter family UPF0546 PF10639.4 KFH43394.1 - 0.0011 18.8 3.0 0.0014 18.4 2.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 EmrE PF13536.1 KFH43394.1 - 0.0068 16.5 10.5 0.0068 16.5 7.3 1.6 1 1 1 2 2 2 1 Multidrug resistance efflux transporter DUF2754 PF10953.3 KFH43394.1 - 0.07 13.2 3.3 0.6 10.2 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2754) Peptidase_U4 PF03419.8 KFH43394.1 - 0.33 9.9 4.3 0.41 9.6 3.0 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA TPT PF03151.11 KFH43394.1 - 1.3 8.6 11.8 0.38 10.3 4.7 1.9 1 1 1 2 2 2 0 Triose-phosphate Transporter family DUF2456 PF10445.4 KFH43394.1 - 1.9 8.4 5.3 1.4 8.9 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2456) Ribosomal_S7 PF00177.16 KFH43395.1 - 1.6e-41 141.3 0.9 1.9e-41 141.1 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Nucleoplasmin PF03066.10 KFH43396.1 - 0.0086 15.5 3.5 0.01 15.3 2.5 1.2 1 0 0 1 1 1 1 Nucleoplasmin CENP-B_dimeris PF09026.5 KFH43396.1 - 0.028 14.6 4.7 0.041 14.1 3.3 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RXT2_N PF08595.6 KFH43396.1 - 0.049 13.4 4.4 0.038 13.7 1.9 1.6 2 0 0 2 2 2 0 RXT2-like, N-terminal FAM176 PF14851.1 KFH43396.1 - 0.079 12.6 2.6 0.095 12.3 1.8 1.3 1 0 0 1 1 1 0 FAM176 family CRT10 PF08728.5 KFH43396.1 - 0.081 10.9 1.6 0.091 10.7 1.1 1.0 1 0 0 1 1 1 0 CRT10 TRAP_alpha PF03896.11 KFH43396.1 - 0.16 10.9 4.4 0.23 10.4 3.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nucleo_P87 PF07267.6 KFH43396.1 - 0.24 10.0 2.1 0.27 9.8 1.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 ORC6 PF05460.8 KFH43396.1 - 0.44 9.5 7.7 0.72 8.8 5.3 1.4 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Nop14 PF04147.7 KFH43396.1 - 0.52 8.1 11.1 0.58 8.0 7.7 1.0 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.7 KFH43396.1 - 1.2 8.9 6.9 1.4 8.7 4.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PBP1_TM PF14812.1 KFH43396.1 - 1.2 9.5 13.2 2.5 8.4 9.2 1.6 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_60s PF00428.14 KFH43396.1 - 4.9 7.6 9.2 12 6.3 6.4 1.8 1 1 0 1 1 1 0 60s Acidic ribosomal protein Trypan_PARP PF05887.6 KFH43399.1 - 0.00032 20.5 22.6 0.00032 20.5 15.6 3.5 3 0 0 3 3 3 1 Procyclic acidic repetitive protein (PARP) Glyco_hydro_17 PF00332.13 KFH43400.1 - 1.1e-05 24.6 0.0 1.6e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 WXG100 PF06013.7 KFH43400.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Proteins of 100 residues with WXG DUF605 PF04652.11 KFH43400.1 - 6.1 6.1 18.8 9 5.5 13.0 1.2 1 0 0 1 1 1 0 Vta1 like Rep_fac_C PF08542.6 KFH43402.1 - 1.8e-16 59.9 0.1 2.9e-15 55.9 0.0 2.4 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.24 KFH43402.1 - 1.5e-15 57.5 0.0 3.5e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KFH43402.1 - 1.8e-12 47.2 0.4 8.7e-12 44.9 0.0 2.3 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Rad17 PF03215.10 KFH43402.1 - 1.8e-11 43.4 0.0 1.5e-08 33.7 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein DNA_pol3_delta PF06144.8 KFH43402.1 - 5.3e-07 29.3 0.0 9.1e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.1 KFH43402.1 - 7.1e-07 29.4 0.1 1.5e-05 25.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 KFH43402.1 - 2.4e-06 26.5 0.0 0.005 15.6 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 KFH43402.1 - 2.5e-06 27.1 0.0 6.5e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KFH43402.1 - 7.9e-06 25.9 0.1 0.00022 21.2 0.0 2.8 1 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 KFH43402.1 - 9e-06 24.9 0.1 0.00013 21.1 0.0 2.4 2 1 1 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KFH43402.1 - 4.8e-05 23.2 0.0 8.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KFH43402.1 - 6.6e-05 22.5 0.0 0.0004 19.9 0.0 2.3 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 KFH43402.1 - 6.9e-05 22.5 0.1 0.00015 21.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFH43402.1 - 8e-05 22.3 0.1 0.00026 20.7 0.1 1.9 1 1 1 2 2 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 KFH43402.1 - 8.7e-05 22.1 0.0 0.00017 21.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 KFH43402.1 - 0.00031 19.7 0.0 0.00056 18.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.1 KFH43402.1 - 0.0019 17.7 0.1 0.0039 16.8 0.1 1.5 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KFH43402.1 - 0.0027 16.8 0.1 0.045 12.9 0.1 2.5 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI PhoH PF02562.11 KFH43402.1 - 0.0038 16.4 0.9 1.7 7.8 0.0 2.7 2 1 0 3 3 3 1 PhoH-like protein AAA_25 PF13481.1 KFH43402.1 - 0.0071 15.7 0.0 0.041 13.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KFH43402.1 - 0.012 15.0 0.0 0.087 12.2 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.1 KFH43402.1 - 0.02 15.7 0.0 0.046 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KFH43402.1 - 0.021 14.8 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KFH43402.1 - 0.023 14.1 0.0 0.32 10.4 0.0 2.5 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_10 PF12846.2 KFH43402.1 - 0.023 14.1 0.1 0.24 10.7 0.1 2.4 1 1 0 1 1 1 0 AAA-like domain AAA_18 PF13238.1 KFH43402.1 - 0.028 14.7 0.0 0.063 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain MCM PF00493.18 KFH43402.1 - 0.037 12.8 0.0 0.087 11.6 0.0 1.6 1 1 0 1 1 1 0 MCM2/3/5 family DEAD PF00270.24 KFH43402.1 - 0.05 13.0 0.0 0.88 9.0 0.0 2.2 1 1 0 2 2 2 0 DEAD/DEAH box helicase BLOC1_2 PF10046.4 KFH43402.1 - 0.052 13.6 0.0 0.18 11.9 0.0 1.9 2 0 0 2 2 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RNA_helicase PF00910.17 KFH43402.1 - 0.076 13.2 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase TAFII28 PF04719.9 KFH43402.1 - 0.078 12.7 0.0 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 hTAFII28-like protein conserved region DUF2075 PF09848.4 KFH43402.1 - 0.099 11.5 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 KFH43402.1 - 0.15 11.8 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KFH43402.1 - 0.16 10.6 0.0 4.9 5.8 0.0 2.1 2 0 0 2 2 2 0 SNF2 family N-terminal domain FoP_duplication PF13865.1 KFH43403.1 - 5.5 7.5 6.9 2.9 8.3 3.1 1.8 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 adh_short PF00106.20 KFH43404.1 - 1.4e-22 80.3 0.2 3.1e-22 79.2 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH43404.1 - 1.8e-13 50.8 0.2 8.1e-06 25.7 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH43404.1 - 1.5e-07 31.2 0.4 3.9e-07 29.9 0.3 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KFH43404.1 - 0.001 18.5 0.0 0.045 13.1 0.0 2.3 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFH43404.1 - 0.011 15.7 0.1 0.06 13.3 0.0 2.0 2 1 0 2 2 2 0 NADH(P)-binding NAD_binding_4 PF07993.7 KFH43404.1 - 0.049 12.5 0.2 0.063 12.2 0.1 1.4 1 1 0 1 1 1 0 Male sterility protein Semialdhyde_dh PF01118.19 KFH43404.1 - 0.058 13.6 0.9 5.2 7.3 0.1 3.0 2 1 1 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 KFH43404.1 - 0.079 12.6 0.1 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KFH43404.1 - 0.099 13.0 0.1 0.52 10.7 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent MoCF_biosynth PF00994.19 KFH43405.1 - 1.7e-55 186.3 0.7 8.1e-30 103.1 0.0 2.2 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 KFH43405.1 - 1.1e-36 125.6 3.0 1.6e-36 125.1 2.1 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 KFH43405.1 - 4.4e-13 48.9 0.0 1.4e-12 47.3 0.0 1.9 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) LRR_9 PF14580.1 KFH43406.1 - 1.9e-47 161.1 0.0 3e-47 160.4 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 KFH43406.1 - 1.5e-11 43.9 0.7 9.4e-10 38.1 0.1 3.3 4 0 0 4 4 4 1 Leucine rich repeat LRR_4 PF12799.2 KFH43406.1 - 6.6e-11 41.5 3.9 2.6e-07 30.1 0.3 3.8 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KFH43406.1 - 0.00062 19.5 1.2 1.8 9.1 0.1 4.8 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 KFH43406.1 - 0.00071 19.3 0.6 7.1 7.0 0.0 4.2 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.28 KFH43406.1 - 0.0042 16.9 3.6 59 4.2 0.1 5.3 5 0 0 5 5 5 0 Leucine Rich Repeat DUF4349 PF14257.1 KFH43406.1 - 4.8 6.3 10.2 0.06 12.5 2.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) DUF2419 PF10343.4 KFH43407.1 - 3.9e-128 426.7 0.1 4.6e-128 426.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) DUF1563 PF07599.6 KFH43407.1 - 0.076 12.9 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1563) cNMP_binding PF00027.24 KFH43409.1 - 3.4e-38 129.3 0.0 3.2e-18 65.3 0.0 4.8 4 1 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.17 KFH43409.1 - 2e-18 67.0 4.4 1.1e-17 64.6 2.4 2.7 2 1 0 2 2 2 1 Patatin-like phospholipase tRNA-synt_1d PF00750.14 KFH43410.1 - 5.5e-77 258.9 2.7 9e-77 258.2 1.8 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 KFH43410.1 - 1.4e-26 92.8 0.1 3.7e-26 91.4 0.1 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 KFH43410.1 - 0.00023 21.6 0.0 0.0005 20.5 0.0 1.6 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain DUF3484 PF11983.3 KFH43410.1 - 0.19 12.5 0.9 0.75 10.6 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3484) TFIIA_gamma_C PF02751.9 KFH43411.1 - 1.1e-25 89.2 0.8 1.4e-25 88.7 0.5 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 KFH43411.1 - 4.8e-25 86.8 0.3 6.9e-25 86.3 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TIP49 PF06068.8 KFH43412.1 - 8.1e-173 574.6 1.9 9.6e-173 574.4 1.3 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 KFH43412.1 - 4.4e-09 36.6 0.3 5.9e-06 26.5 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KFH43412.1 - 6.7e-09 35.1 0.5 3.3e-05 23.0 0.0 2.7 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KFH43412.1 - 2.6e-06 27.5 0.0 4e-05 23.6 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.10 KFH43412.1 - 4.5e-06 25.7 0.5 7.5e-06 25.0 0.3 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.1 KFH43412.1 - 0.00019 21.5 0.0 0.94 9.6 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KFH43412.1 - 0.0012 18.6 0.0 1.2 9.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 KFH43412.1 - 0.0015 17.7 1.0 0.019 14.1 0.2 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KFH43412.1 - 0.0017 17.7 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KFH43412.1 - 0.0062 16.5 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFH43412.1 - 0.029 14.1 0.3 0.1 12.3 0.2 1.9 1 1 0 1 1 1 0 Part of AAA domain Sigma54_activat PF00158.21 KFH43412.1 - 0.034 13.6 0.1 9.5 5.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.9 KFH43412.1 - 0.038 13.7 0.1 4.2 7.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 KFH43412.1 - 0.049 13.1 0.0 0.078 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KFH43412.1 - 0.056 13.7 0.1 0.35 11.1 0.0 2.4 2 2 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 KFH43412.1 - 0.075 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 KFH43412.1 - 0.091 12.2 0.8 2.2 7.6 0.0 2.6 2 1 0 2 2 2 0 FtsK/SpoIIIE family Parvo_NS1 PF01057.12 KFH43412.1 - 0.15 10.9 0.1 0.29 9.9 0.1 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DNA_pol_delta_4 PF04081.8 KFH43413.1 - 1.7e-31 109.0 5.7 6.5e-31 107.2 4.0 1.8 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 DUF4629 PF15442.1 KFH43413.1 - 0.63 10.1 3.8 0.93 9.6 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) ATP_bind_1 PF03029.12 KFH43414.1 - 7.1e-76 254.8 0.0 8.8e-76 254.5 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 KFH43414.1 - 0.0039 16.0 0.2 0.0081 14.9 0.0 1.5 2 0 0 2 2 2 1 ArgK protein AAA_29 PF13555.1 KFH43414.1 - 0.015 14.7 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 KFH43414.1 - 0.072 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 KFH43414.1 - 0.078 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KFH43414.1 - 0.14 11.2 0.2 0.42 9.6 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.1 KFH43414.1 - 1.7 9.4 5.9 0.46 11.2 0.5 2.6 2 2 0 2 2 2 0 AAA domain Zip PF02535.17 KFH43415.1 - 1.4e-57 195.1 5.4 1.8e-56 191.5 3.7 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter GYF PF02213.11 KFH43416.1 - 3e-11 42.7 1.0 7.1e-11 41.5 0.7 1.7 1 0 0 1 1 1 1 GYF domain Herpes_US9 PF06072.6 KFH43416.1 - 0.026 14.3 0.2 3 7.7 0.0 2.7 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 RNase_P_Rpp14 PF01900.14 KFH43417.1 - 5.4e-35 119.5 0.0 6.9e-35 119.2 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family PTS_IIA PF02255.11 KFH43417.1 - 0.093 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit Ribosomal_S25 PF03297.10 KFH43418.1 - 1.4e-39 134.3 3.4 1.5e-39 134.2 2.4 1.0 1 0 0 1 1 1 1 S25 ribosomal protein MarR_2 PF12802.2 KFH43418.1 - 0.02 14.5 0.1 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.15 KFH43418.1 - 0.038 14.0 0.0 0.056 13.5 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator Septin PF00735.13 KFH43419.1 - 4e-113 377.1 0.5 4.7e-113 376.8 0.3 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KFH43419.1 - 2e-06 27.7 0.0 3.3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 KFH43419.1 - 4.8e-06 25.8 0.0 8.3e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 KFH43419.1 - 8.3e-06 25.3 0.2 0.0021 17.5 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KFH43419.1 - 3.6e-05 23.0 0.0 6.4e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KFH43419.1 - 0.00097 18.9 0.2 1.1 9.0 0.1 2.5 1 1 1 2 2 2 2 Dynamin family AAA_10 PF12846.2 KFH43419.1 - 0.0043 16.5 0.1 0.0043 16.5 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain Gtr1_RagA PF04670.7 KFH43419.1 - 0.0065 15.6 0.1 0.1 11.7 0.0 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 KFH43419.1 - 0.0074 16.4 0.0 0.016 15.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KFH43419.1 - 0.0085 16.3 0.3 0.016 15.5 0.2 1.7 1 1 0 1 1 1 1 ABC transporter AAA_23 PF13476.1 KFH43419.1 - 0.018 15.3 0.0 0.03 14.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KFH43419.1 - 0.035 13.5 0.0 0.068 12.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family NB-ARC PF00931.17 KFH43419.1 - 0.035 12.9 0.0 0.056 12.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.1 KFH43419.1 - 0.042 13.8 0.0 0.061 13.2 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain T2SE PF00437.15 KFH43419.1 - 0.061 12.2 0.0 0.14 11.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Miro PF08477.8 KFH43419.1 - 0.13 12.7 0.0 0.42 11.1 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein AAA_29 PF13555.1 KFH43419.1 - 0.16 11.4 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Acetyltransf_1 PF00583.19 KFH43420.1 - 5.3e-06 26.3 0.0 1.2e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.1 KFH43420.1 - 6.3e-05 23.4 0.1 0.0066 16.9 0.0 2.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KFH43420.1 - 0.00031 20.8 0.0 0.00099 19.2 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain CENP-X PF09415.5 KFH43421.1 - 2.2e-24 85.0 1.3 5.8e-24 83.7 0.1 1.9 2 0 0 2 2 2 1 CENP-S associating Centromere protein X CBFD_NFYB_HMF PF00808.18 KFH43421.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2611 PF11022.3 KFH43422.1 - 8.2 6.5 6.3 6 7.0 2.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2611) HSF_DNA-bind PF00447.12 KFH43423.1 - 1.4e-34 118.3 0.5 2.2e-34 117.7 0.4 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding UNC45-central PF11701.3 KFH43425.1 - 3.7e-49 166.3 0.0 1.4e-48 164.5 0.0 2.1 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central HEAT_2 PF13646.1 KFH43425.1 - 0.0045 17.2 16.4 1.4 9.2 0.2 6.4 4 3 3 7 7 7 3 HEAT repeats CLASP_N PF12348.3 KFH43425.1 - 0.045 13.1 0.0 0.25 10.6 0.0 2.3 2 0 0 2 2 2 0 CLASP N terminal Arm PF00514.18 KFH43425.1 - 0.42 10.5 10.6 39 4.2 0.1 6.6 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat zf-CCCH PF00642.19 KFH43426.1 - 4.3e-06 26.2 0.9 4.3e-06 26.2 0.6 2.3 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PTPS PF01242.14 KFH43426.1 - 0.015 14.9 0.3 2.8 7.6 0.0 2.4 2 0 0 2 2 2 0 6-pyruvoyl tetrahydropterin synthase ARGLU PF15346.1 KFH43426.1 - 5.5 6.7 37.1 4.5 7.0 3.3 3.3 3 0 0 3 3 3 0 Arginine and glutamate-rich 1 Amino_oxidase PF01593.19 KFH43427.1 - 5.1e-16 58.7 0.2 4.1e-13 49.2 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KFH43427.1 - 5.3e-12 45.5 0.1 1.3e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFH43427.1 - 2.7e-08 33.1 0.0 0.0007 18.6 0.0 3.2 3 0 0 3 3 3 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KFH43427.1 - 5e-07 29.9 0.1 0.00031 20.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFH43427.1 - 0.00054 19.7 0.0 0.34 10.6 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KFH43427.1 - 0.00092 19.1 0.0 0.0045 16.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFH43427.1 - 0.0038 15.7 0.0 0.46 8.8 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 KFH43427.1 - 0.017 14.0 0.0 0.036 12.8 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 KFH43427.1 - 0.054 12.5 0.0 0.076 12.0 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 KFH43427.1 - 0.056 12.5 0.0 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.17 KFH43427.1 - 0.081 11.7 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.22 KFH43427.1 - 0.15 12.5 0.0 0.46 10.9 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Tcf25 PF04910.9 KFH43428.1 - 3.2e-70 236.8 0.0 5.3e-70 236.1 0.0 1.4 1 0 0 1 1 1 1 Transcriptional repressor TCF25 CS PF04969.11 KFH43429.1 - 4.2e-11 43.2 0.0 6.1e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 CS domain V-SNARE PF05008.10 KFH43430.1 - 2.2e-23 82.2 2.3 2.2e-23 82.2 1.6 2.1 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 KFH43430.1 - 9e-17 60.9 2.7 9e-17 60.9 1.8 2.7 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Fusion_gly PF00523.13 KFH43430.1 - 0.0028 15.8 1.6 0.039 12.0 0.2 2.1 2 0 0 2 2 2 1 Fusion glycoprotein F0 Sec20 PF03908.8 KFH43430.1 - 0.0093 15.6 1.5 0.015 14.9 0.3 2.0 2 2 0 2 2 2 1 Sec20 Prominin PF05478.6 KFH43430.1 - 0.043 11.3 2.5 0.99 6.8 0.2 2.0 2 0 0 2 2 2 0 Prominin YvbH_ext PF11724.3 KFH43430.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 YvbH-like oligomerisation region Laminin_I PF06008.9 KFH43430.1 - 0.46 9.7 6.4 0.11 11.7 0.6 2.4 2 2 1 3 3 3 0 Laminin Domain I Mnd1 PF03962.10 KFH43430.1 - 0.49 10.0 2.4 0.43 10.2 0.4 1.8 1 1 0 1 1 1 0 Mnd1 family Synaptobrevin PF00957.16 KFH43430.1 - 0.63 9.6 6.0 1 9.0 1.4 2.4 1 1 0 2 2 2 0 Synaptobrevin Cutinase PF01083.17 KFH43431.1 - 3e-49 167.1 0.0 3.8e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 KFH43431.1 - 6.5e-05 22.4 0.0 9.1e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.6 KFH43431.1 - 0.00046 20.0 0.0 0.00065 19.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) DUF3089 PF11288.3 KFH43431.1 - 0.015 14.4 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Abhydrolase_5 PF12695.2 KFH43431.1 - 0.1 12.3 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFH43431.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family 60KD_IMP PF02096.15 KFH43432.1 - 1.7e-13 50.6 0.0 2.5e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein CtaG_Cox11 PF04442.9 KFH43433.1 - 1.9e-57 193.2 0.1 2.3e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DUF4129 PF13559.1 KFH43434.1 - 0.016 15.2 2.5 0.045 13.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) NICE-3 PF07406.6 KFH43434.1 - 0.069 12.6 0.2 2.4 7.6 0.0 2.2 2 0 0 2 2 2 0 NICE-3 protein Thiolase_C PF02803.13 KFH43437.1 - 2e-10 40.1 0.9 4.9e-10 38.8 0.1 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KFH43437.1 - 1.2e-06 28.1 0.3 6.1e-05 22.5 0.1 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 KFH43437.1 - 0.00018 20.6 0.9 0.00041 19.4 0.0 2.1 3 0 0 3 3 3 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 KFH43437.1 - 0.0084 15.6 0.2 0.016 14.6 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.6 KFH43437.1 - 0.0096 14.4 0.6 0.045 12.1 0.1 2.0 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) Ketoacyl-synt_C PF02801.17 KFH43437.1 - 0.014 15.2 1.5 0.37 10.6 0.0 3.0 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain Mito_carr PF00153.22 KFH43438.1 - 6e-43 144.4 7.7 2.7e-16 59.0 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein AT_hook PF02178.14 KFH43439.1 - 0.012 15.2 20.6 0.027 14.1 2.0 3.5 3 0 0 3 3 3 0 AT hook motif tRNA_U5-meth_tr PF05958.6 KFH43440.1 - 2.9e-11 42.6 0.0 1.1e-09 37.4 0.0 2.4 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.5 KFH43440.1 - 3.7e-07 29.8 0.0 6.3e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.1 KFH43440.1 - 1.7e-06 27.7 0.0 2.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH43440.1 - 0.0019 18.7 0.0 0.0038 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 KFH43440.1 - 0.01 15.2 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 TRAM PF01938.15 KFH43440.1 - 0.022 14.5 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 TRAM domain MTS PF05175.9 KFH43440.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.7 KFH43440.1 - 0.15 12.5 0.0 0.43 11.0 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 KFH43440.1 - 0.16 11.1 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) VEK-30 PF12107.3 KFH43441.1 - 0.7 9.6 5.5 1.6 8.4 3.8 1.6 1 0 0 1 1 1 0 Plasminogen (Pg) ligand in fibrinolytic pathway Prefoldin_2 PF01920.15 KFH43442.1 - 3.3e-24 84.6 9.3 4.2e-24 84.3 6.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit THOC7 PF05615.8 KFH43442.1 - 0.029 14.6 0.4 0.029 14.6 0.3 2.0 2 0 0 2 2 2 0 Tho complex subunit 7 AAA_23 PF13476.1 KFH43442.1 - 0.14 12.4 7.5 0.17 12.2 5.2 1.0 1 0 0 1 1 1 0 AAA domain eIF-4B PF06273.6 KFH43442.1 - 0.76 8.4 6.2 0.93 8.1 4.3 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B XhlA PF10779.4 KFH43442.1 - 1.9 8.4 5.7 5.8 6.8 3.9 2.0 1 1 0 1 1 1 0 Haemolysin XhlA Rho_Binding PF08912.6 KFH43442.1 - 8.5 6.7 14.0 0.34 11.2 0.9 2.7 3 0 0 3 3 3 0 Rho Binding ADH_N PF08240.7 KFH43443.1 - 2.7e-29 101.1 0.5 4.8e-29 100.3 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFH43443.1 - 1.2e-23 83.0 0.2 2.2e-23 82.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF1967 PF09269.6 KFH43443.1 - 0.014 15.0 0.0 0.044 13.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) NAD_binding_10 PF13460.1 KFH43443.1 - 0.12 12.3 0.4 0.19 11.6 0.3 1.3 1 0 0 1 1 1 0 NADH(P)-binding UQ_con PF00179.21 KFH43444.1 - 2.8e-06 26.8 0.0 5.8e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Pkinase PF00069.20 KFH43445.1 - 5.2e-07 29.0 0.0 1e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KFH43445.1 - 0.0096 15.6 0.7 0.026 14.2 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KFH43445.1 - 0.07 12.1 0.0 0.19 10.7 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.27 KFH43446.1 - 2e-17 62.2 0.2 1.1e-08 34.6 0.0 6.3 6 0 0 6 6 6 2 WD domain, G-beta repeat DUF3639 PF12341.3 KFH43446.1 - 7.3e-11 41.8 1.4 7.3e-11 41.8 1.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3639) Coatomer_WDAD PF04053.9 KFH43446.1 - 0.00039 19.3 0.0 0.0006 18.7 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region eIF2A PF08662.6 KFH43446.1 - 0.0012 18.5 0.1 0.0035 17.0 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A GDE_N_bis PF14742.1 KFH43446.1 - 0.0076 15.6 0.1 8.4 5.7 0.0 3.7 4 0 0 4 4 4 1 N-terminal domain of (some) glycogen debranching enzymes Apc4_WD40 PF12894.2 KFH43446.1 - 0.011 15.2 0.0 4.3 6.9 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.7 KFH43446.1 - 0.1 10.3 0.1 0.18 9.5 0.1 1.4 1 0 0 1 1 1 0 IKI3 family RXT2_N PF08595.6 KFH43446.1 - 1.2 8.9 3.8 2.2 8.0 2.7 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Tfb4 PF03850.9 KFH43447.1 - 2.2e-93 312.4 0.0 2.7e-93 312.2 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 zf-C2HC5 PF06221.8 KFH43447.1 - 0.016 14.9 4.3 0.026 14.2 3.0 1.3 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type TerY-C PF15616.1 KFH43447.1 - 0.17 11.8 2.0 0.3 11.0 1.4 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain Ost4 PF10215.4 KFH43448.1 - 1.2e-16 59.8 0.9 1.6e-16 59.4 0.6 1.2 1 0 0 1 1 1 1 Oligosaccaryltransferase Syntaxin_2 PF14523.1 KFH43449.1 - 3.9e-24 84.6 8.1 3.9e-24 84.6 5.6 2.2 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 KFH43449.1 - 2.3e-16 59.2 6.2 3e-16 58.8 3.2 2.0 2 0 0 2 2 2 1 SNARE domain Synaptobrevin PF00957.16 KFH43449.1 - 0.0065 16.0 0.4 0.016 14.8 0.2 1.7 1 0 0 1 1 1 1 Synaptobrevin DUF883 PF05957.8 KFH43449.1 - 0.026 14.8 9.5 0.2 12.0 0.1 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) SPOB_ab PF14682.1 KFH43449.1 - 0.033 13.9 0.1 0.094 12.5 0.1 1.7 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal Vac_Fusion PF02346.11 KFH43449.1 - 0.035 13.5 0.0 0.11 11.9 0.0 1.8 1 0 0 1 1 1 0 Chordopoxvirus fusion protein TSKS PF15358.1 KFH43449.1 - 0.079 11.1 6.5 0.11 10.6 4.5 1.1 1 0 0 1 1 1 0 Testis-specific serine kinase substrate DUF1664 PF07889.7 KFH43449.1 - 0.12 12.1 5.8 5.1 6.9 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) MCPsignal PF00015.16 KFH43449.1 - 0.22 11.0 7.7 0.2 11.1 1.0 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF732 PF05305.9 KFH43449.1 - 0.26 11.3 3.3 2.7 8.1 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF732) T2SM_b PF10741.4 KFH43449.1 - 0.5 10.0 4.6 12 5.5 0.4 2.7 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b Syntaxin PF00804.20 KFH43449.1 - 1.1 9.4 9.5 0.17 12.0 1.7 2.5 2 2 0 2 2 2 0 Syntaxin RmuC PF02646.11 KFH43449.1 - 1.8 7.2 14.0 1.4 7.6 1.4 2.7 3 0 0 3 3 3 0 RmuC family Adaptin_binding PF10199.4 KFH43449.1 - 3.9 7.7 9.0 19 5.4 5.7 2.2 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Snf7 PF03357.16 KFH43450.1 - 2.8e-18 65.8 7.6 2.8e-18 65.8 5.3 2.1 2 0 0 2 2 2 1 Snf7 Ribosomal_60s PF00428.14 KFH43450.1 - 0.021 15.2 5.2 0.021 15.2 3.6 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein TPR_MLP1_2 PF07926.7 KFH43450.1 - 0.022 14.5 6.5 0.051 13.3 4.5 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Smr PF01713.16 KFH43450.1 - 0.2 11.8 0.8 0.5 10.5 0.1 2.0 2 0 0 2 2 2 0 Smr domain GAS PF13851.1 KFH43450.1 - 1.4 8.0 8.2 0.11 11.6 2.1 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Siah-Interact_N PF09032.6 KFH43450.1 - 4.7 7.3 11.8 8.4 6.5 2.0 2.6 2 0 0 2 2 2 0 Siah interacting protein, N terminal Cutinase PF01083.17 KFH43451.1 - 8.7e-33 113.5 0.0 1.1e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 Cutinase VirJ PF06057.6 KFH43451.1 - 0.00053 19.8 0.0 0.00075 19.3 0.0 1.1 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Abhydrolase_6 PF12697.2 KFH43451.1 - 0.0015 18.4 0.1 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH43451.1 - 0.0022 17.7 0.0 0.0027 17.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 KFH43451.1 - 0.0032 16.8 0.0 0.0043 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Lipase_3 PF01764.20 KFH43451.1 - 0.0061 16.1 0.0 0.0078 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.15 KFH43451.1 - 0.018 14.5 0.0 0.025 14.1 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_8 PF06259.7 KFH43451.1 - 0.022 14.2 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase Thioesterase PF00975.15 KFH43451.1 - 0.033 14.4 0.0 0.043 14.0 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain FSH1 PF03959.8 KFH43451.1 - 0.065 12.6 0.0 0.08 12.3 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase (FSH1) RRM_1 PF00076.17 KFH43452.1 - 7.1e-17 60.8 0.0 1.2e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH43452.1 - 7e-14 51.5 0.0 1e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH43452.1 - 1.5e-06 27.9 0.0 2.7e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.10 KFH43452.1 - 0.0028 17.6 0.0 0.0058 16.6 0.0 1.5 1 1 0 1 1 1 1 Smg-4/UPF3 family FoP_duplication PF13865.1 KFH43452.1 - 0.004 17.5 1.3 0.004 17.5 0.9 3.0 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Ribosomal_60s PF00428.14 KFH43454.1 - 0.023 15.0 0.3 0.023 15.0 0.2 4.3 2 1 2 4 4 4 0 60s Acidic ribosomal protein vMSA PF00695.14 KFH43454.1 - 0.43 9.7 2.0 0.68 9.0 1.4 1.3 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Adeno_terminal PF02459.10 KFH43454.1 - 1.7 6.6 16.7 0.2 9.7 2.9 2.1 2 0 0 2 2 2 0 Adenoviral DNA terminal protein SET PF00856.23 KFH43455.1 - 0.042 14.1 0.0 0.16 12.2 0.0 1.9 2 0 0 2 2 2 0 SET domain DUF4407 PF14362.1 KFH43455.1 - 0.1 11.5 4.4 0.13 11.2 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) WD40 PF00400.27 KFH43456.1 - 2.2e-22 78.0 11.1 6.3e-06 25.8 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat CHASE2 PF05226.6 KFH43456.1 - 0.00099 18.4 0.1 0.077 12.2 0.0 2.2 2 0 0 2 2 2 2 CHASE2 domain DUF627 PF04781.7 KFH43456.1 - 0.034 13.7 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF627) PQQ_2 PF13360.1 KFH43456.1 - 0.062 12.7 0.8 3.1 7.2 0.1 2.4 1 1 1 2 2 2 0 PQQ-like domain Sigma70_r1_2 PF00140.15 KFH43456.1 - 0.071 12.8 1.0 0.16 11.6 0.7 1.6 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 Nup160 PF11715.3 KFH43456.1 - 0.096 10.7 0.1 0.2 9.7 0.0 1.6 1 1 0 1 1 1 0 Nucleoporin Nup120/160 BSP_II PF05432.6 KFH43457.1 - 0.00089 18.6 7.0 0.00089 18.6 4.9 2.9 1 1 0 2 2 2 1 Bone sialoprotein II (BSP-II) TMEM154 PF15102.1 KFH43457.1 - 0.03 14.0 4.4 0.078 12.6 3.1 1.7 1 0 0 1 1 1 0 TMEM154 protein family Nop14 PF04147.7 KFH43457.1 - 0.38 8.6 41.1 0.032 12.1 7.0 2.1 2 0 0 2 2 2 0 Nop14-like family BUD22 PF09073.5 KFH43457.1 - 0.98 8.4 35.1 1.8 7.5 6.9 2.1 2 0 0 2 2 2 0 BUD22 Spore_coat_CotO PF14153.1 KFH43457.1 - 4.8 6.5 13.9 3.5 7.0 5.8 2.2 2 0 0 2 2 2 0 Spore coat protein CotO SDA1 PF05285.7 KFH43457.1 - 6 6.0 41.4 0.15 11.3 6.8 2.1 2 0 0 2 2 2 0 SDA1 CENP-T PF15511.1 KFH43457.1 - 9.3 5.3 28.8 33 3.5 19.9 1.7 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Thr_synth_N PF14821.1 KFH43458.1 - 1.3e-28 98.8 0.0 1.3e-27 95.6 0.0 2.3 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.20 KFH43458.1 - 1.3e-19 70.5 0.0 6.4e-19 68.3 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Glycos_transf_1 PF00534.15 KFH43459.1 - 9.1e-21 74.0 0.0 1.4e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KFH43459.1 - 1.1e-10 41.7 0.1 1.7e-09 37.9 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KFH43459.1 - 0.0037 17.0 0.0 0.0074 16.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Meth_synt_2 PF01717.13 KFH43460.1 - 8.4e-143 475.1 0.0 6.8e-137 455.7 0.0 2.5 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KFH43460.1 - 2.3e-124 414.6 0.0 4.4e-112 374.3 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain Bac_small_YrzI PF09501.5 KFH43460.1 - 0.15 12.0 2.7 0.23 11.4 0.6 2.3 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) SHOCT PF09851.4 KFH43460.1 - 8.5 6.0 7.1 0.35 10.3 0.1 2.4 3 0 0 3 3 3 0 Short C-terminal domain LSM14 PF12701.2 KFH43461.1 - 2.8e-34 116.8 0.0 5.3e-34 115.9 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 KFH43461.1 - 8.3e-22 77.7 0.8 8.3e-22 77.7 0.6 1.7 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.1 KFH43461.1 - 1.5e-05 24.8 0.0 2.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain TFIIA PF03153.8 KFH43461.1 - 2.6 7.8 13.8 3.8 7.3 9.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MFS_1 PF07690.11 KFH43462.1 - 5.8e-39 133.7 40.1 5.8e-39 133.7 27.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH43462.1 - 2.5e-15 55.9 15.3 1.9e-14 53.1 7.0 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter PTR2 PF00854.16 KFH43462.1 - 0.0088 14.8 1.1 0.0088 14.8 0.8 2.1 2 0 0 2 2 2 1 POT family HMA PF00403.21 KFH43463.1 - 1e-12 47.9 1.0 1e-05 25.5 0.1 2.2 2 0 0 2 2 2 2 Heavy-metal-associated domain G_glu_transpept PF01019.16 KFH43464.1 - 3.1e-154 514.2 0.3 1.8e-153 511.6 0.2 1.8 1 1 0 1 1 1 1 Gamma-glutamyltranspeptidase CBFD_NFYB_HMF PF00808.18 KFH43465.1 - 5.6e-05 23.1 0.1 7.5e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.1 KFH43465.1 - 0.055 13.4 0.2 0.13 12.2 0.1 1.7 1 1 0 1 1 1 0 Centromere kinetochore component W Ndc1_Nup PF09531.5 KFH43466.1 - 5.8e-128 427.9 0.0 6.8e-128 427.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Actin PF00022.14 KFH43467.1 - 1.1e-89 300.5 0.0 2.1e-89 299.7 0.0 1.4 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KFH43467.1 - 0.016 13.8 0.0 1.2 7.6 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein Asparaginase_2 PF01112.13 KFH43468.1 - 3e-36 124.7 2.0 3.4e-20 72.0 0.0 2.2 2 0 0 2 2 2 2 Asparaginase Period_C PF12114.3 KFH43469.1 - 3.4 7.2 7.9 4.5 6.8 5.5 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Acetyltransf_1 PF00583.19 KFH43471.1 - 2.3e-14 53.1 0.0 3.8e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFH43471.1 - 3.6e-08 33.4 0.0 6.1e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFH43471.1 - 4.2e-06 26.4 0.0 7.5e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KFH43471.1 - 5.3e-06 26.5 0.0 1e-05 25.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KFH43471.1 - 1.4e-05 25.2 0.0 3.3e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KFH43471.1 - 0.0013 18.7 0.0 0.0025 17.7 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KFH43471.1 - 0.0097 15.7 0.0 0.031 14.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFH43471.1 - 0.011 15.6 0.0 0.035 13.9 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain YflT PF11181.3 KFH43471.1 - 0.13 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Heat induced stress protein YflT TFIIA PF03153.8 KFH43472.1 - 1.8e-78 265.0 17.0 2.5e-78 264.6 11.8 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 KFH43472.1 - 0.15 10.2 42.5 0.25 9.5 29.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 KFH43472.1 - 1.5 8.0 30.9 2.5 7.3 21.4 1.3 1 0 0 1 1 1 0 Vta1 like SOG2 PF10428.4 KFH43472.1 - 2.7 6.5 9.5 3.4 6.2 6.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4407 PF14362.1 KFH43472.1 - 3.4 6.5 10.9 4.7 6.0 7.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3138 PF11336.3 KFH43472.1 - 4.6 5.3 10.9 6.7 4.7 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF1223 PF06764.6 KFH43473.1 - 0.042 13.6 0.1 0.059 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) DUF972 PF06156.8 KFH43473.1 - 0.54 10.6 4.1 0.18 12.1 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Kelch_4 PF13418.1 KFH43474.1 - 6.3e-30 102.6 7.6 1.2e-08 34.5 0.0 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 KFH43474.1 - 2.4e-25 87.9 2.5 6.7e-07 29.1 0.0 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 KFH43474.1 - 3.3e-25 87.1 2.3 5.1e-05 23.2 0.0 5.3 4 1 1 5 5 5 4 Kelch motif Kelch_3 PF13415.1 KFH43474.1 - 2.9e-23 81.4 7.5 3.5e-07 30.2 0.0 5.8 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.20 KFH43474.1 - 3.7e-22 77.5 0.2 3.9e-05 23.0 0.0 4.7 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 KFH43474.1 - 6.3e-22 76.4 1.8 4.7e-06 26.1 0.0 4.7 4 0 0 4 4 4 4 Kelch motif BTB PF00651.26 KFH43474.1 - 4.7e-09 36.2 0.0 8e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Rax2 PF12768.2 KFH43474.1 - 0.11 11.6 0.0 0.84 8.7 0.0 2.1 1 1 1 2 2 2 0 Cortical protein marker for cell polarity PH_6 PF15406.1 KFH43475.1 - 7.9e-40 135.4 1.7 7.9e-40 135.4 1.2 3.7 4 0 0 4 4 4 1 Pleckstrin homology domain PH PF00169.24 KFH43475.1 - 0.0058 16.8 0.0 0.017 15.2 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_4 PF15404.1 KFH43475.1 - 0.72 9.3 0.0 0.72 9.3 0.0 3.3 4 1 0 4 4 4 0 Pleckstrin homology domain SUR7 PF06687.7 KFH43476.1 - 5e-29 101.4 0.6 6e-29 101.1 0.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family HATPase_c PF02518.21 KFH43477.1 - 7e-24 83.6 0.1 1.4e-23 82.7 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KFH43477.1 - 7.4e-22 77.4 0.3 2.2e-21 75.9 0.2 1.9 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 KFH43477.1 - 1.3e-10 41.6 0.0 1.1e-09 38.5 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 KFH43477.1 - 4.1e-08 33.2 0.0 0.00012 22.0 0.0 2.9 2 0 0 2 2 2 2 PAS fold HisKA PF00512.20 KFH43477.1 - 1.5e-07 31.3 1.0 2.9e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.1 KFH43477.1 - 1.5e-05 25.4 0.0 0.023 15.1 0.0 2.6 2 0 0 2 2 2 2 GAF domain PAS PF00989.19 KFH43477.1 - 5.9e-05 22.8 0.0 0.0016 18.2 0.0 3.0 3 0 0 3 3 3 1 PAS fold GAF_3 PF13492.1 KFH43477.1 - 0.0017 18.4 0.0 0.14 12.2 0.0 2.5 2 0 0 2 2 2 1 GAF domain PAS_3 PF08447.6 KFH43477.1 - 0.0018 18.3 0.4 0.0062 16.6 0.0 2.1 2 0 0 2 2 2 1 PAS fold HATPase_c_3 PF13589.1 KFH43477.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_L36 PF00444.13 KFH43478.1 - 1.4e-21 76.1 14.4 2.6e-21 75.3 10.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L36 Molybdopterin PF00384.17 KFH43478.1 - 0.04 12.6 0.0 0.048 12.4 0.0 1.0 1 0 0 1 1 1 0 Molybdopterin oxidoreductase ADH_N PF08240.7 KFH43479.1 - 3.9e-27 94.1 2.2 6.9e-27 93.3 1.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFH43479.1 - 8.3e-16 57.7 0.0 1.3e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase S1-like PF14444.1 KFH43479.1 - 0.012 15.3 0.1 0.42 10.3 0.0 2.4 2 0 0 2 2 2 0 S1-like UDPGP PF01704.13 KFH43480.1 - 9.1e-55 185.8 0.0 1.2e-54 185.4 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 KFH43480.1 - 0.045 13.8 0.0 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 MobA-like NTP transferase domain Fer4_20 PF14691.1 KFH43480.1 - 0.07 12.7 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster fn3 PF00041.16 KFH43481.1 - 7.3e-08 32.4 0.0 2.2e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain T2SF PF00482.18 KFH43481.1 - 4.2 7.2 5.6 5.4 6.9 2.2 2.3 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F YniB PF14002.1 KFH43481.1 - 5.7 6.3 3.7 9 5.7 0.1 2.3 2 0 0 2 2 2 0 YniB-like protein DUF812 PF05667.6 KFH43481.1 - 6.2 5.1 32.7 10 4.4 22.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Filament PF00038.16 KFH43481.1 - 7 6.0 43.6 1.9 7.8 16.7 2.3 1 1 1 2 2 2 0 Intermediate filament protein RRF PF01765.14 KFH43483.1 - 1e-26 93.3 0.6 1.4e-26 92.9 0.4 1.2 1 0 0 1 1 1 1 Ribosome recycling factor ATP-synt_B PF00430.13 KFH43483.1 - 0.22 11.3 6.8 0.32 10.8 4.7 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DSPc PF00782.15 KFH43484.1 - 6.2e-15 54.9 0.0 1.8e-11 43.7 0.0 2.1 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFH43484.1 - 0.087 12.1 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Histidinol_dh PF00815.15 KFH43485.1 - 3.1e-180 599.2 4.7 4.4e-180 598.7 3.2 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 KFH43485.1 - 2.5e-24 84.6 0.0 5.7e-24 83.5 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 KFH43485.1 - 6.3e-10 39.2 0.2 1.9e-09 37.6 0.1 1.9 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase WD40 PF00400.27 KFH43488.1 - 3.7e-25 86.8 16.7 1.7e-06 27.6 0.1 7.1 6 1 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KFH43488.1 - 4e-06 26.6 0.6 0.00053 19.7 0.1 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 KFH43488.1 - 0.052 13.0 0.0 0.55 9.7 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain zf-C2H2_4 PF13894.1 KFH43490.1 - 0.00012 22.1 9.0 0.45 10.9 0.2 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFH43490.1 - 0.0016 18.5 3.0 0.054 13.6 0.1 3.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 KFH43490.1 - 0.0019 18.4 13.4 0.41 11.0 0.3 4.3 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFH43490.1 - 0.016 15.4 0.5 0.016 15.4 0.4 3.1 3 0 0 3 3 3 0 Zinc-finger double domain IMPDH PF00478.20 KFH43491.1 - 3.9e-132 440.4 1.0 4.8e-132 440.1 0.7 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 KFH43491.1 - 5.5e-19 67.6 0.1 2.8e-09 36.6 0.0 2.4 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 KFH43491.1 - 6.7e-08 31.7 1.4 5.9e-07 28.6 0.4 2.2 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 KFH43491.1 - 1e-06 28.1 4.3 0.027 13.6 3.1 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.16 KFH43491.1 - 0.0028 16.9 2.1 0.063 12.5 1.5 2.2 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.9 KFH43491.1 - 0.092 11.8 1.4 0.15 11.1 0.2 1.8 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG WD40 PF00400.27 KFH43492.1 - 7.8e-21 73.1 4.7 1.1e-08 34.6 0.0 8.2 7 0 0 7 7 7 4 WD domain, G-beta repeat GSDH PF07995.6 KFH43492.1 - 0.082 11.9 0.0 0.6 9.1 0.0 2.5 2 0 0 2 2 2 0 Glucose / Sorbosone dehydrogenase Nucleoporin_N PF08801.6 KFH43492.1 - 0.18 10.4 0.2 4 6.0 0.0 3.0 3 1 0 3 3 3 0 Nup133 N terminal like FA_hydroxylase PF04116.8 KFH43493.1 - 1e-15 58.1 13.6 1e-15 58.1 9.4 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Calmodulin_bind PF07887.6 KFH43494.1 - 0.1 11.6 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Calmodulin binding protein-like zf-CCHC_4 PF14392.1 KFH43494.1 - 0.15 11.7 0.1 0.15 11.7 0.1 1.9 2 0 0 2 2 2 0 Zinc knuckle ATP-synt_G PF04718.10 KFH43495.1 - 5e-30 104.1 1.0 1.3e-29 102.8 0.1 1.8 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit Complex1_LYR_1 PF13232.1 KFH43497.1 - 7.8e-20 70.8 0.2 1.1e-19 70.3 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KFH43497.1 - 4.7e-19 67.9 0.2 7.6e-19 67.2 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 KFH43497.1 - 0.018 15.5 0.3 0.03 14.7 0.0 1.5 2 0 0 2 2 2 0 Complex1_LYR-like Trypsin PF00089.21 KFH43498.1 - 1.3e-66 224.3 2.4 1.5e-66 224.1 1.6 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 KFH43498.1 - 8.1e-07 29.0 1.3 2.5e-06 27.4 0.9 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S32 PF05579.8 KFH43498.1 - 0.029 13.3 3.3 0.076 11.9 0.5 2.2 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 Aldedh PF00171.17 KFH43499.1 - 1.1e-165 551.4 0.1 1.2e-165 551.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KFH43499.1 - 0.019 14.2 0.0 0.1 11.8 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) ADP_ribosyl_GH PF03747.9 KFH43499.1 - 0.69 9.6 6.2 0.048 13.4 0.4 1.9 2 1 0 2 2 2 0 ADP-ribosylglycohydrolase LNS2 PF08235.8 KFH43500.1 - 8.8e-71 236.5 0.1 1.6e-70 235.6 0.1 1.5 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 KFH43500.1 - 3.6e-41 139.3 0.0 1.9e-40 136.9 0.0 2.2 3 0 0 3 3 3 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 KFH43500.1 - 0.0012 18.2 0.0 0.072 12.4 0.0 2.4 2 0 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) AF1Q PF15017.1 KFH43500.1 - 0.014 15.2 0.3 0.014 15.2 0.2 3.1 3 0 0 3 3 3 0 Drug resistance and apoptosis regulator PMT PF02366.13 KFH43500.1 - 0.27 10.5 0.0 0.41 9.9 0.0 1.1 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase zf-MYND PF01753.13 KFH43501.1 - 1e-07 31.7 3.1 1.8e-07 30.9 2.2 1.4 1 0 0 1 1 1 1 MYND finger Metallophos PF00149.23 KFH43502.1 - 3.5e-39 134.2 0.2 4.6e-39 133.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TFIID-31kDa PF02291.10 KFH43503.1 - 2.9e-28 98.2 0.0 4.9e-27 94.2 0.0 2.1 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Mucin PF01456.12 KFH43503.1 - 0.69 9.6 9.9 0.27 10.9 2.8 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein Pkinase PF00069.20 KFH43505.1 - 1.4e-08 34.2 0.0 1.7e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH43505.1 - 1.8e-06 27.1 0.0 3.1e-06 26.4 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH43505.1 - 0.0024 16.8 0.0 0.003 16.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFH43505.1 - 0.0069 16.1 1.0 0.027 14.2 0.1 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Complex1_LYR_1 PF13232.1 KFH43505.1 - 0.045 13.9 0.1 0.095 12.9 0.1 1.5 1 0 0 1 1 1 0 Complex1_LYR-like Complex1_LYR PF05347.10 KFH43505.1 - 0.11 12.2 0.2 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Pyr_redox_2 PF07992.9 KFH43506.1 - 1.9e-16 60.5 0.0 2.7e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFH43506.1 - 5.7e-08 32.6 0.1 0.00025 20.8 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KFH43506.1 - 4.5e-07 30.1 0.3 0.025 14.6 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KFH43506.1 - 1.2e-06 27.7 0.6 0.0016 17.4 0.1 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.17 KFH43506.1 - 1.5e-06 27.3 0.3 0.011 14.5 0.0 2.2 1 1 1 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.9 KFH43506.1 - 2.1e-05 23.2 0.1 0.0048 15.4 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein K_oxygenase PF13434.1 KFH43506.1 - 0.00021 20.3 0.2 0.00089 18.2 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 KFH43506.1 - 0.0014 17.5 0.2 0.015 14.1 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KFH43506.1 - 0.003 17.5 0.2 0.0068 16.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KFH43506.1 - 0.0041 16.0 0.0 0.097 11.5 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 KFH43506.1 - 0.08 12.0 0.1 0.13 11.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pkinase PF00069.20 KFH43507.1 - 6.6e-23 81.1 0.0 8.3e-11 41.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFH43507.1 - 1.7e-06 27.3 0.0 0.017 14.1 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 KFH43507.1 - 0.012 15.3 0.0 0.085 12.5 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KFH43507.1 - 0.034 13.0 0.0 4.9 6.0 0.0 2.5 3 0 0 3 3 3 0 Kinase-like adh_short_C2 PF13561.1 KFH43508.1 - 2.4e-29 102.8 0.0 2.9e-29 102.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFH43508.1 - 5.7e-23 81.6 0.1 7.1e-23 81.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH43508.1 - 5e-07 29.5 0.0 9.1e-07 28.7 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KFH43508.1 - 0.0042 16.5 0.0 0.006 16.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family MFS_1 PF07690.11 KFH43509.1 - 1.7e-33 115.8 46.8 8.5e-22 77.3 15.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH43509.1 - 1.3e-12 47.0 30.8 1.4e-06 27.2 8.3 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 KFH43509.1 - 7.2e-07 27.9 14.2 7.2e-07 27.9 9.8 2.2 1 1 2 3 3 3 1 MFS/sugar transport protein MFS_1_like PF12832.2 KFH43509.1 - 0.00039 20.1 2.7 0.041 13.6 0.1 3.0 3 0 0 3 3 3 2 MFS_1 like family Arif-1 PF06770.6 KFH43509.1 - 2.8 7.2 4.8 5.9 6.2 3.3 1.5 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) Acyltransferase PF01553.16 KFH43511.1 - 1.6e-17 63.1 0.0 3.2e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DUF559 PF04480.7 KFH43511.1 - 0.078 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF559) DUF1308 PF07000.6 KFH43512.1 - 3.1e-29 101.7 0.1 4.6e-29 101.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) GYF PF02213.11 KFH43513.1 - 8.8e-18 63.6 0.0 1.7e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 GYF domain LMBR1 PF04791.11 KFH43513.1 - 1.3 7.5 0.2 1.8 7.0 0.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein AA_permease PF00324.16 KFH43514.1 - 2.7e-91 306.3 35.2 3.3e-91 306.0 24.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFH43514.1 - 3.8e-24 85.0 41.2 4.5e-24 84.7 28.5 1.0 1 0 0 1 1 1 1 Amino acid permease GMC_oxred_N PF00732.14 KFH43515.1 - 3.4e-30 105.2 0.0 7.2e-17 61.4 0.0 3.2 2 1 1 3 3 3 3 GMC oxidoreductase GMC_oxred_C PF05199.8 KFH43515.1 - 1.4e-27 96.7 0.0 2.7e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KFH43515.1 - 0.00014 21.8 0.9 0.00045 20.1 0.7 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFH43515.1 - 0.0028 16.6 0.7 0.013 14.4 0.4 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase ApbA PF02558.11 KFH43515.1 - 0.0041 16.5 0.4 0.0082 15.5 0.3 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 KFH43515.1 - 0.0079 16.0 0.0 0.031 14.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFH43515.1 - 0.027 13.3 0.5 0.047 12.5 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 KFH43515.1 - 0.11 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 KFH43515.1 - 0.17 10.2 0.1 0.26 9.7 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.13 KFH43515.1 - 0.21 11.2 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Macro PF01661.16 KFH43517.1 - 3e-39 133.5 0.1 4.4e-39 133.0 0.0 1.3 1 0 0 1 1 1 1 Macro domain DUF3138 PF11336.3 KFH43517.1 - 0.85 7.7 4.0 0.59 8.2 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) MMS1_N PF10433.4 KFH43518.1 - 1.9e-81 273.7 0.0 9.3e-81 271.4 0.0 1.8 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 KFH43518.1 - 4.7e-58 196.7 0.0 1.8e-57 194.8 0.0 2.1 3 0 0 3 3 3 1 CPSF A subunit region Beta_propel PF09826.4 KFH43518.1 - 0.17 10.2 0.0 0.3 9.3 0.0 1.3 1 0 0 1 1 1 0 Beta propeller domain tRNA-synt_1c PF00749.16 KFH43521.1 - 9.8e-98 326.6 0.0 9.8e-98 326.6 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KFH43521.1 - 2.1e-31 108.9 0.0 5.2e-31 107.6 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Zn_Tnp_IS1 PF03811.8 KFH43521.1 - 0.13 11.8 3.3 0.25 10.8 2.3 1.5 1 0 0 1 1 1 0 InsA N-terminal domain WD40 PF00400.27 KFH43522.1 - 2e-20 71.8 2.7 0.00069 19.4 0.0 6.0 5 1 0 5 5 5 5 WD domain, G-beta repeat HAD_2 PF13419.1 KFH43523.1 - 6.5e-12 46.0 0.0 7.8e-06 26.2 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFH43523.1 - 3.4e-05 24.3 0.0 0.013 15.8 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFH43523.1 - 4.9e-05 22.9 0.0 0.00014 21.5 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Exo_endo_phos PF03372.18 KFH43525.1 - 7.2e-10 39.2 2.0 9.1e-10 38.8 1.4 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HOASN PF14515.1 KFH43525.1 - 0.11 12.8 0.3 0.27 11.6 0.2 1.6 1 0 0 1 1 1 0 Haem-oxygenase-associated N-terminal helices DUF4467 PF14729.1 KFH43526.1 - 0.038 14.3 0.2 0.068 13.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function with cystatin-like fold (DUF4467) Acyl_transf_1 PF00698.16 KFH43527.1 - 5.8e-89 298.5 1.0 9.9e-89 297.7 0.7 1.4 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 KFH43527.1 - 2.2e-83 279.6 0.1 5e-83 278.4 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KFH43527.1 - 5.3e-59 198.9 1.5 2e-58 197.0 0.3 2.3 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KFH43527.1 - 3.9e-49 166.7 1.8 1.9e-48 164.5 0.4 2.6 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KFH43527.1 - 1.4e-42 144.2 0.8 5.1e-42 142.4 0.2 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 KFH43527.1 - 4.5e-20 71.9 0.1 8.1e-20 71.1 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 KFH43527.1 - 4.7e-13 49.2 0.0 1.1e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KFH43527.1 - 1e-05 24.6 1.6 5e-05 22.4 0.1 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain tRNA-synt_2b PF00587.20 KFH43528.1 - 3.2e-21 75.6 0.0 9.3e-21 74.1 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.6 KFH43528.1 - 4.3e-20 71.4 0.3 9.9e-20 70.2 0.2 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.15 KFH43528.1 - 1.8e-18 66.2 0.0 5.2e-18 64.7 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain Glyco_hydro_61 PF03443.9 KFH43529.1 - 4.3e-63 213.0 0.0 5.2e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 UCR_TM PF02921.9 KFH43530.1 - 4.9e-19 68.3 0.2 8.7e-19 67.5 0.1 1.4 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 KFH43530.1 - 2.5e-17 62.2 0.0 4.2e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain WD40 PF00400.27 KFH43531.1 - 0.0058 16.4 12.4 2.2 8.2 1.2 5.7 6 0 0 6 6 6 2 WD domain, G-beta repeat Leu_leader PF08054.6 KFH43531.1 - 0.06 12.9 0.2 0.13 11.9 0.2 1.6 1 0 0 1 1 1 0 Leucine operon leader peptide Cpn60_TCP1 PF00118.19 KFH43532.1 - 1.8e-146 488.5 8.0 2.1e-146 488.4 5.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Peroxidase_2 PF01328.12 KFH43533.1 - 2.9e-10 39.3 0.0 4.4e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Pantoate_ligase PF02569.10 KFH43534.1 - 1.6e-78 263.3 0.0 2.8e-78 262.5 0.0 1.4 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase Ion_trans PF00520.26 KFH43535.1 - 3.9e-07 29.5 20.3 2.6e-06 26.8 11.7 2.9 2 1 0 2 2 2 2 Ion transport protein PQ-loop PF04193.9 KFH43536.1 - 1.9e-20 72.1 7.6 1.1e-11 44.0 1.4 3.1 3 1 0 3 3 3 2 PQ loop repeat YiiD_Cterm PF09500.5 KFH43536.1 - 0.061 12.8 0.0 0.09 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative thioesterase (yiiD_Cterm) MtN3_slv PF03083.11 KFH43536.1 - 0.56 10.1 3.7 1.9 8.4 0.1 2.9 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange UPF0086 PF01868.11 KFH43537.1 - 6.7e-23 80.1 0.1 1e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function UPF0086 AMP-binding PF00501.23 KFH43538.1 - 2.7e-65 220.3 0.0 3.6e-65 219.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFH43538.1 - 2.2e-12 47.7 0.2 6.4e-12 46.2 0.2 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TPR_11 PF13414.1 KFH43539.1 - 1.2e-11 44.0 10.2 4.4e-10 39.0 0.0 5.8 6 1 1 7 7 7 1 TPR repeat TPR_2 PF07719.12 KFH43539.1 - 2.1e-09 36.5 7.5 0.0047 16.7 0.0 5.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFH43539.1 - 2.5e-09 37.5 0.2 2.5e-09 37.5 0.1 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFH43539.1 - 3.7e-09 35.8 0.7 0.011 15.2 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFH43539.1 - 9.2e-06 25.9 1.9 0.18 12.1 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFH43539.1 - 1.8e-05 24.9 1.2 0.00032 21.0 0.3 6.2 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFH43539.1 - 2.8e-05 23.5 1.5 0.11 12.2 0.0 4.7 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFH43539.1 - 4e-05 23.0 9.0 0.13 12.1 0.0 4.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFH43539.1 - 0.00047 20.0 15.1 0.1 12.5 0.0 4.8 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFH43539.1 - 0.0072 16.4 0.1 0.21 11.8 0.0 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 KFH43539.1 - 0.018 14.2 0.0 0.04 13.1 0.0 1.6 1 0 0 1 1 1 0 SHNi-TPR DUF849 PF05853.7 KFH43539.1 - 0.17 10.7 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic protein of unknown function (DUF849) Coatomer_WDAD PF04053.9 KFH43539.1 - 0.27 9.9 0.0 0.45 9.2 0.0 1.3 1 0 0 1 1 1 0 Coatomer WD associated region CFEM PF05730.6 KFH43540.1 - 2.3e-13 49.7 10.8 3.7e-13 49.1 7.5 1.3 1 0 0 1 1 1 1 CFEM domain PsbH PF00737.15 KFH43540.1 - 1.5 8.4 7.6 0.39 10.3 2.4 2.3 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein PKD_channel PF08016.7 KFH43541.1 - 5.4e-06 25.0 17.8 9.5e-05 20.9 12.3 2.1 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 KFH43541.1 - 0.0019 17.5 24.6 0.059 12.6 17.1 2.4 1 1 0 1 1 1 1 Ion transport protein COX2-transmemb PF09125.5 KFH43541.1 - 0.2 11.2 1.9 0.82 9.2 1.3 2.1 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane SR-25 PF10500.4 KFH43542.1 - 1.8 7.9 5.1 2.7 7.4 3.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cyt-b5 PF00173.23 KFH43543.1 - 1.9e-15 56.4 0.3 1.1e-05 25.0 0.0 3.6 3 0 0 3 3 3 3 Cytochrome b5-like Heme/Steroid binding domain Cellulase PF00150.13 KFH43545.1 - 2.3e-11 43.4 0.2 1.7e-07 30.7 0.1 2.5 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) MFS_1 PF07690.11 KFH43546.1 - 3.1e-41 141.2 53.5 3.1e-41 141.2 37.1 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KFH43546.1 - 3.7e-14 51.8 19.1 1.3e-13 50.0 13.2 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Renin_r PF07850.9 KFH43546.1 - 0.017 15.4 0.2 0.15 12.4 0.0 2.4 2 0 0 2 2 2 0 Renin receptor-like protein DUF4131 PF13567.1 KFH43546.1 - 5.2 6.4 20.1 0.1 11.9 1.1 4.4 1 1 4 5 5 5 0 Domain of unknown function (DUF4131) Peptidase_U4 PF03419.8 KFH43546.1 - 7.4 5.5 6.8 2.5 7.1 1.6 2.3 1 1 0 2 2 2 0 Sporulation factor SpoIIGA TPR_11 PF13414.1 KFH43547.1 - 3.3e-09 36.2 1.2 7.8e-09 35.0 0.8 1.6 1 0 0 1 1 1 1 TPR repeat TPR_12 PF13424.1 KFH43547.1 - 0.037 13.9 2.8 0.047 13.6 0.4 2.2 2 1 0 2 2 2 0 Tetratricopeptide repeat FadA PF09403.5 KFH43547.1 - 0.75 9.8 7.1 0.58 10.1 0.1 2.6 3 0 0 3 3 3 0 Adhesion protein FadA ABC_tran PF00005.22 KFH43548.1 - 2.3e-47 160.7 0.1 6.8e-24 84.7 0.0 3.5 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KFH43548.1 - 4.4e-18 66.2 0.0 0.0007 19.6 0.0 4.4 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 KFH43548.1 - 2.2e-16 59.7 0.1 1.5e-05 24.3 0.0 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KFH43548.1 - 3.8e-10 39.1 0.0 0.0012 18.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KFH43548.1 - 4e-10 40.3 1.9 0.00013 22.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 KFH43548.1 - 4.2e-08 34.0 0.0 0.0058 17.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KFH43548.1 - 5.8e-08 32.9 0.0 0.00077 19.6 0.0 3.2 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 KFH43548.1 - 5.8e-08 32.0 0.0 0.00051 19.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_28 PF13521.1 KFH43548.1 - 5e-07 29.8 0.1 0.017 15.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KFH43548.1 - 7.4e-07 29.1 0.0 0.0056 16.6 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_10 PF12846.2 KFH43548.1 - 2.6e-06 27.1 0.1 0.26 10.7 0.0 3.4 3 0 0 3 3 3 2 AAA-like domain AAA_33 PF13671.1 KFH43548.1 - 3.6e-06 26.9 0.0 0.13 12.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 KFH43548.1 - 5.3e-06 26.3 0.0 0.0016 18.2 0.0 2.9 2 0 0 2 2 2 1 Dynamin family AAA_15 PF13175.1 KFH43548.1 - 8.2e-06 25.1 9.2 0.11 11.5 0.0 5.0 4 1 1 5 5 5 2 AAA ATPase domain Miro PF08477.8 KFH43548.1 - 9.9e-06 26.0 0.0 0.045 14.2 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_18 PF13238.1 KFH43548.1 - 1.2e-05 25.6 4.2 0.16 12.2 0.0 4.8 6 0 0 6 6 4 2 AAA domain SbcCD_C PF13558.1 KFH43548.1 - 1.2e-05 25.1 0.0 0.04 13.8 0.0 3.4 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA PF00004.24 KFH43548.1 - 1.3e-05 25.3 0.0 0.26 11.4 0.0 4.2 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 KFH43548.1 - 1.6e-05 23.8 0.1 0.15 10.8 0.0 2.4 2 0 0 2 2 2 2 ArgK protein MobB PF03205.9 KFH43548.1 - 2.9e-05 23.7 0.0 0.34 10.5 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KFH43548.1 - 4.6e-05 23.4 0.2 0.91 9.4 0.0 4.1 4 0 0 4 4 4 1 AAA ATPase domain PduV-EutP PF10662.4 KFH43548.1 - 6.1e-05 22.5 0.1 0.11 11.9 0.0 3.2 3 1 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation HEAT_2 PF13646.1 KFH43548.1 - 6.2e-05 23.1 3.8 0.13 12.5 2.9 3.0 1 1 1 2 2 2 1 HEAT repeats RNA_helicase PF00910.17 KFH43548.1 - 7.5e-05 22.8 0.0 0.66 10.1 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_13 PF13166.1 KFH43548.1 - 9e-05 21.1 0.2 1.3 7.3 0.0 3.6 3 1 0 3 3 3 2 AAA domain NACHT PF05729.7 KFH43548.1 - 0.00018 21.2 0.0 0.098 12.3 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.1 KFH43548.1 - 0.00021 21.2 0.0 1.5 8.7 0.0 3.5 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 KFH43548.1 - 0.00024 20.9 0.0 0.8 9.3 0.0 2.9 2 0 0 2 2 2 2 Archaeal ATPase DUF87 PF01935.12 KFH43548.1 - 0.0013 18.5 0.0 0.9 9.3 0.0 3.4 3 0 0 3 3 2 1 Domain of unknown function DUF87 Cnd1 PF12717.2 KFH43548.1 - 0.0015 18.4 0.1 0.01 15.7 0.0 2.2 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Septin PF00735.13 KFH43548.1 - 0.002 17.1 0.7 0.75 8.7 0.0 2.9 3 0 0 3 3 3 1 Septin cobW PF02492.14 KFH43548.1 - 0.0022 17.4 0.0 2.3 7.6 0.0 3.1 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.20 KFH43548.1 - 0.0032 17.0 0.0 2.1 7.8 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.1 KFH43548.1 - 0.004 16.7 0.0 5.9 6.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain CLASP_N PF12348.3 KFH43548.1 - 0.0056 16.0 0.0 0.024 14.0 0.0 2.0 1 1 1 2 2 2 1 CLASP N terminal AAA_25 PF13481.1 KFH43548.1 - 0.0063 15.9 0.0 5.5 6.3 0.0 3.1 3 0 0 3 3 2 0 AAA domain HEAT PF02985.17 KFH43548.1 - 0.0069 16.3 0.7 9.4 6.6 0.1 4.0 3 0 0 3 3 3 0 HEAT repeat MutS_V PF00488.16 KFH43548.1 - 0.0076 15.6 0.1 0.76 9.1 0.0 2.4 2 0 0 2 2 2 1 MutS domain V ATP_bind_1 PF03029.12 KFH43548.1 - 0.0099 15.4 0.2 7.1 6.0 0.0 3.1 4 0 0 4 4 2 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.7 KFH43548.1 - 0.027 13.5 0.0 6 5.9 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin T2SE PF00437.15 KFH43548.1 - 0.031 13.1 0.1 3 6.6 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein PRK PF00485.13 KFH43548.1 - 0.033 13.7 0.0 1 8.8 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family FtsK_SpoIIIE PF01580.13 KFH43548.1 - 0.035 13.5 0.1 4.9 6.5 0.0 2.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family NB-ARC PF00931.17 KFH43548.1 - 0.046 12.5 0.0 0.5 9.1 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Mg_chelatase PF01078.16 KFH43548.1 - 0.047 12.8 0.0 3.2 6.8 0.0 2.7 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.10 KFH43548.1 - 0.048 12.3 0.0 4.1 5.9 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Transglut_prok PF09017.5 KFH43548.1 - 0.059 12.4 0.1 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Microbial transglutaminase AAA_19 PF13245.1 KFH43548.1 - 0.11 12.2 0.0 6.1 6.6 0.0 2.8 2 0 0 2 2 2 0 Part of AAA domain HEAT_EZ PF13513.1 KFH43548.1 - 0.15 12.6 7.6 0.77 10.3 0.0 5.0 5 2 2 7 7 5 0 HEAT-like repeat G-alpha PF00503.15 KFH43548.1 - 0.64 8.6 5.7 1.1 7.8 0.0 2.6 3 0 0 3 3 2 0 G-protein alpha subunit ApbA PF02558.11 KFH43549.1 - 5e-24 84.4 0.0 7.2e-24 83.9 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 KFH43549.1 - 1.5e-21 76.6 0.0 2.4e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Myb_DNA-bind_6 PF13921.1 KFH43550.1 - 2.5e-05 24.3 0.1 5.9e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KFH43550.1 - 0.022 14.8 0.1 0.039 13.9 0.1 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain OPT PF03169.10 KFH43551.1 - 5.1e-182 606.5 51.3 5.9e-182 606.3 35.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Ribosomal_S4e PF00900.15 KFH43552.1 - 9.4e-32 108.5 0.2 2.1e-31 107.3 0.1 1.6 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 KFH43552.1 - 5.3e-18 64.5 1.8 1e-17 63.6 1.2 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 KFH43552.1 - 7.6e-06 25.2 0.0 1.4e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 KFH43552.1 - 0.0023 17.5 1.0 0.0023 17.5 0.7 3.2 4 0 0 4 4 4 1 KOW motif ADH_zinc_N PF00107.21 KFH43553.1 - 2e-25 88.8 0.5 3.1e-25 88.1 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFH43553.1 - 2.9e-16 59.1 0.7 7.3e-16 57.8 0.5 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 KFH43553.1 - 2.5e-05 23.9 0.6 6.6e-05 22.5 0.3 1.7 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 KFH43553.1 - 3.4e-05 23.8 0.1 5.5e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.14 KFH43553.1 - 0.0014 17.8 0.1 0.0025 17.0 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CMAS PF02353.15 KFH43553.1 - 0.002 17.2 0.0 0.003 16.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase SIMPL PF04402.9 KFH43553.1 - 0.005 16.7 0.1 0.26 11.1 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF541) ELFV_dehydrog PF00208.16 KFH43553.1 - 0.007 15.9 0.3 0.011 15.3 0.2 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 3HCDH_N PF02737.13 KFH43553.1 - 0.01 15.4 0.7 0.017 14.7 0.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_11 PF08241.7 KFH43553.1 - 0.015 15.8 0.2 0.038 14.4 0.2 1.8 1 1 0 1 1 1 0 Methyltransferase domain Cellsynth_D PF03500.8 KFH43553.1 - 0.028 14.0 0.1 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 Cellulose synthase subunit D B12-binding PF02310.14 KFH43553.1 - 0.032 14.1 0.1 0.061 13.1 0.1 1.4 1 0 0 1 1 1 0 B12 binding domain Methyltransf_25 PF13649.1 KFH43553.1 - 0.04 14.2 0.0 0.084 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_2 PF03446.10 KFH43553.1 - 0.064 13.1 0.5 0.16 11.7 0.3 1.6 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase RdRP PF05183.7 KFH43554.1 - 1.7e-178 594.9 0.0 2.3e-178 594.5 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase SnoaL PF07366.7 KFH43556.1 - 0.00018 21.1 0.0 0.00022 20.8 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase EthD PF07110.6 KFH43557.1 - 1.2e-18 67.8 2.2 1.7e-18 67.2 1.5 1.2 1 0 0 1 1 1 1 EthD domain Raptor_N PF14538.1 KFH43558.1 - 2.5e-65 219.0 0.0 5.7e-65 217.8 0.0 1.7 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 KFH43558.1 - 1.4e-10 40.6 1.3 0.61 10.0 0.0 6.5 6 0 0 6 6 6 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 KFH43558.1 - 9.1e-06 25.4 0.2 0.046 13.4 0.1 2.6 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region HEAT PF02985.17 KFH43558.1 - 0.0028 17.5 1.1 1.4 9.1 0.0 4.8 6 0 0 6 6 6 1 HEAT repeat Atx10homo_assoc PF09759.4 KFH43558.1 - 0.019 14.7 0.1 0.037 13.7 0.1 1.5 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain Nup160 PF11715.3 KFH43558.1 - 0.02 13.0 0.5 0.054 11.6 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 DUF1900 PF08954.6 KFH43558.1 - 0.06 12.8 0.0 11 5.5 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1900) CDP-OH_P_transf PF01066.16 KFH43559.1 - 8.2e-17 61.3 1.1 8.2e-17 61.3 0.8 2.4 3 0 0 3 3 3 1 CDP-alcohol phosphatidyltransferase FAD-oxidase_C PF02913.14 KFH43560.1 - 6.1e-61 205.8 0.1 1.4e-59 201.4 0.0 2.2 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KFH43560.1 - 3.4e-34 117.2 0.0 6.6e-34 116.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain SLA_LP_auto_ag PF05889.8 KFH43560.1 - 0.015 13.7 0.1 0.025 13.0 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) SUR7 PF06687.7 KFH43561.1 - 8.3e-09 35.3 16.0 1e-08 35.0 11.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family NfeD PF01957.13 KFH43561.1 - 0.0022 18.1 1.5 0.0022 18.1 1.0 1.8 1 1 1 2 2 2 1 NfeD-like C-terminal, partner-binding 2TM PF13239.1 KFH43561.1 - 0.18 11.8 0.6 0.33 11.0 0.2 1.5 1 1 0 1 1 1 0 2TM domain Pox_P21 PF05313.7 KFH43561.1 - 1.1 8.4 9.3 2 7.6 6.5 1.3 1 0 0 1 1 1 0 Poxvirus P21 membrane protein Peptidase_U4 PF03419.8 KFH43561.1 - 1.1 8.2 6.7 1.5 7.8 4.6 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA MARVEL PF01284.18 KFH43561.1 - 3.9 7.2 13.8 12 5.6 9.8 1.4 1 1 0 1 1 1 0 Membrane-associating domain ABC1 PF03109.11 KFH43562.1 - 1.8e-18 66.6 0.0 3.7e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 KFH43562.1 - 0.067 12.9 0.1 0.55 9.9 0.0 2.3 3 0 0 3 3 3 0 Phosphotransferase enzyme family DUF2348 PF09807.4 KFH43563.1 - 4.9e-06 25.8 0.0 1.9e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2348) KaiC PF06745.8 KFH43563.1 - 0.034 13.2 0.0 0.059 12.4 0.0 1.3 1 1 0 1 1 1 0 KaiC Thioredoxin PF00085.15 KFH43564.1 - 9.5e-09 34.8 0.0 1.4e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KFH43564.1 - 9.7e-06 25.6 0.0 0.083 13.0 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 KFH43564.1 - 0.00063 19.9 0.0 0.0049 17.0 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KFH43564.1 - 0.002 18.1 0.1 0.004 17.1 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 KFH43564.1 - 0.0064 16.1 0.0 0.0094 15.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family DUF953 PF06110.6 KFH43564.1 - 0.017 14.5 0.0 0.13 11.6 0.0 2.0 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Redoxin PF08534.5 KFH43564.1 - 0.075 12.5 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Redoxin Thioredoxin_9 PF14595.1 KFH43564.1 - 0.11 12.0 0.0 0.32 10.5 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin NAC PF01849.13 KFH43567.1 - 4.8e-21 74.0 1.0 5.8e-21 73.7 0.1 1.6 2 0 0 2 2 2 1 NAC domain Ribosomal_L24e PF01246.15 KFH43568.1 - 4.8e-30 103.2 0.4 4.8e-30 103.2 0.3 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e Glyco_hydro_25 PF01183.15 KFH43569.1 - 7.5e-44 149.7 1.9 8.7e-44 149.5 1.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Myb_DNA-binding PF00249.26 KFH43570.1 - 6.1e-13 48.6 0.8 3.8e-07 30.0 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFH43570.1 - 7.6e-12 45.1 0.1 0.00015 21.8 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.5 KFH43570.1 - 0.019 14.6 0.7 1.2 8.8 0.1 2.5 2 1 0 2 2 2 0 SLIDE SMC_N PF02463.14 KFH43571.1 - 1.3e-26 93.1 0.0 2.2e-26 92.4 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KFH43571.1 - 2e-15 57.6 38.1 1.4e-13 51.6 8.5 4.8 3 1 0 3 3 3 2 AAA domain AAA_21 PF13304.1 KFH43571.1 - 3.5e-08 33.7 0.2 0.0007 19.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain Baculo_PEP_C PF04513.7 KFH43571.1 - 0.00021 21.1 11.8 1.1 9.0 0.1 5.2 4 1 1 5 5 5 1 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 KFH43571.1 - 0.00061 19.0 9.4 0.045 12.9 0.2 4.0 2 2 2 4 4 4 1 Reovirus sigma C capsid protein AAA_25 PF13481.1 KFH43571.1 - 0.0013 18.2 0.5 0.19 11.0 0.0 3.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KFH43571.1 - 0.0045 16.4 0.0 0.0088 15.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain BLOC1_2 PF10046.4 KFH43571.1 - 0.0047 17.0 0.9 0.0047 17.0 0.7 6.3 6 1 0 6 6 6 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 HAUS6_N PF14661.1 KFH43571.1 - 0.0063 15.8 7.6 0.0063 15.8 5.3 5.8 3 2 3 6 6 5 2 HAUS augmin-like complex subunit 6 N-terminus DivIC PF04977.10 KFH43571.1 - 0.0076 15.7 4.9 0.0076 15.7 3.4 8.7 6 3 2 8 8 8 1 Septum formation initiator UCR_hinge PF02320.11 KFH43571.1 - 0.035 14.0 2.7 0.8 9.6 0.4 3.3 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase hinge protein Spc7 PF08317.6 KFH43571.1 - 0.22 10.1 64.7 0.29 9.7 11.6 4.8 2 2 3 5 5 5 0 Spc7 kinetochore protein AAA_13 PF13166.1 KFH43571.1 - 1.4 7.3 55.4 0.97 7.8 11.3 4.3 3 2 1 4 4 4 0 AAA domain NPV_P10 PF05531.7 KFH43571.1 - 6.5 7.0 14.3 11 6.4 0.2 6.0 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF1943 PF09172.6 KFH43571.1 - 7.6 5.3 7.6 0.87 8.3 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) Ribosomal_L37e PF01907.14 KFH43572.1 - 9.6e-27 92.5 11.4 1.5e-26 91.9 7.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 KFH43572.1 - 0.0079 15.9 1.9 0.013 15.3 1.3 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.1 KFH43572.1 - 0.26 10.8 2.2 11 5.6 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 KFH43572.1 - 0.49 9.6 2.7 2.1 7.6 1.8 1.9 1 1 2 3 3 3 0 zinc-ribbon domain GATA PF00320.22 KFH43572.1 - 0.54 9.6 5.0 4.3 6.7 0.1 2.3 1 1 1 2 2 2 0 GATA zinc finger zf-C3HC4 PF00097.20 KFH43572.1 - 1.1 8.9 4.9 1.8 8.2 3.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_S14 PF00253.16 KFH43572.1 - 3.7 6.9 8.9 7.3 6.0 0.1 2.5 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e Cyclin PF08613.6 KFH43573.1 - 1.3e-15 58.1 0.0 3.4e-15 56.7 0.0 1.8 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KFH43573.1 - 0.00054 19.5 0.0 0.0013 18.2 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain 2OG-FeII_Oxy_3 PF13640.1 KFH43574.1 - 9.2e-09 35.7 0.0 1.7e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KFH43574.1 - 0.12 12.7 0.0 0.3 11.3 0.0 1.7 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Kelch_5 PF13854.1 KFH43575.1 - 8.5e-34 114.9 4.9 4.3e-08 32.9 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.1 KFH43575.1 - 7.1e-33 112.1 10.4 1.8e-07 30.8 0.0 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.20 KFH43575.1 - 2.8e-30 103.5 4.1 3.5e-10 39.2 0.5 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.1 KFH43575.1 - 4.4e-30 103.1 19.0 1.5e-08 34.5 0.2 6.6 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_6 PF13964.1 KFH43575.1 - 9e-28 95.2 4.1 2.7e-07 30.4 0.2 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.10 KFH43575.1 - 3.2e-21 74.2 7.1 7.3e-07 28.7 0.2 6.4 6 0 0 6 6 6 5 Kelch motif Tropomyosin_1 PF12718.2 KFH43575.1 - 4.8e-05 23.2 12.2 4.8e-05 23.2 8.5 7.5 3 2 5 8 8 8 2 Tropomyosin like RAG2 PF03089.9 KFH43575.1 - 0.067 11.9 0.0 2.2 6.9 0.0 3.0 4 0 0 4 4 4 0 Recombination activating protein 2 DEAD PF00270.24 KFH43576.1 - 3.9e-36 124.0 0.0 6.5e-36 123.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFH43576.1 - 2.1e-24 85.1 0.1 3.4e-23 81.2 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFH43576.1 - 2.2e-05 24.3 0.0 6.6e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 KFH43576.1 - 0.033 13.2 0.0 0.21 10.6 0.0 2.1 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit bZIP_1 PF00170.16 KFH43577.1 - 7.1e-08 32.3 17.5 1.3e-07 31.4 12.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor FlaC_arch PF05377.6 KFH43577.1 - 0.017 14.9 2.1 0.029 14.2 1.5 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) CCDC155 PF14662.1 KFH43577.1 - 0.022 14.3 8.8 0.031 13.8 6.1 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 bZIP_Maf PF03131.12 KFH43577.1 - 0.025 14.8 10.3 0.04 14.1 7.1 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor ADIP PF11559.3 KFH43577.1 - 0.059 13.2 10.5 0.091 12.6 7.3 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF966 PF06136.8 KFH43577.1 - 0.12 11.7 4.7 0.16 11.3 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) V_ATPase_I PF01496.14 KFH43577.1 - 0.15 9.8 0.8 0.18 9.6 0.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 KFH43577.1 - 0.44 10.9 4.4 0.51 10.7 2.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF972) APG6 PF04111.7 KFH43577.1 - 1.2 8.0 6.1 1.7 7.5 4.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 M PF02370.11 KFH43577.1 - 2.2 8.8 8.7 1.8 9.1 2.1 3.0 1 1 0 2 2 2 0 M protein repeat bZIP_2 PF07716.10 KFH43577.1 - 2.6 7.9 19.1 8 6.3 13.3 1.8 1 1 0 1 1 1 0 Basic region leucine zipper PAT1 PF09770.4 KFH43577.1 - 4.2 5.4 19.6 5.5 5.1 13.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Acyl-CoA_dh_1 PF00441.19 KFH43579.1 - 1.4e-33 116.1 0.1 2.2e-33 115.4 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFH43579.1 - 6.8e-18 63.9 0.9 1.3e-17 63.0 0.6 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KFH43579.1 - 2e-11 44.4 0.4 4.7e-10 40.0 0.1 2.9 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KFH43579.1 - 4.2e-07 30.2 0.0 9e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Rpr2 PF04032.11 KFH43580.1 - 1.2e-22 79.5 0.1 2e-22 78.8 0.1 1.4 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain N-SET PF11764.3 KFH43580.1 - 1.1 9.1 5.4 0.16 11.8 1.0 1.5 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component N MFS_1 PF07690.11 KFH43581.1 - 8.6e-36 123.3 25.5 5.7e-27 94.3 3.6 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH43581.1 - 1.8e-09 36.7 8.6 1.8e-09 36.7 6.0 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KFH43581.1 - 0.00025 19.3 1.4 0.00049 18.4 1.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) eIF_4EBP PF05456.6 KFH43581.1 - 0.017 14.7 0.5 0.043 13.5 0.4 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Septin PF00735.13 KFH43582.1 - 1.8e-30 105.9 0.2 1.4e-11 43.9 0.0 3.1 3 0 0 3 3 3 3 Septin AAA_23 PF13476.1 KFH43582.1 - 0.0025 18.1 2.4 0.0075 16.6 1.7 1.8 1 1 0 1 1 1 1 AAA domain Miro PF08477.8 KFH43582.1 - 0.0062 17.0 0.1 0.076 13.5 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 KFH43582.1 - 0.021 14.7 0.0 0.068 13.1 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 KFH43582.1 - 0.035 13.9 0.3 0.67 9.7 0.0 2.5 2 0 0 2 2 2 0 Dynamin family FtsK_SpoIIIE PF01580.13 KFH43582.1 - 0.08 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Fumble PF03630.9 KFH43583.1 - 1.8e-131 438.0 0.0 1.9e-130 434.6 0.0 2.0 1 1 0 1 1 1 1 Fumble PT PF04886.7 KFH43583.1 - 0.046 13.0 4.6 0.095 12.0 3.2 1.5 1 0 0 1 1 1 0 PT repeat Sel1 PF08238.7 KFH43584.1 - 1.6e-44 149.3 20.9 2e-06 28.2 0.0 8.0 7 0 0 7 7 7 7 Sel1 repeat TPR_17 PF13431.1 KFH43584.1 - 0.0025 17.8 0.2 0.83 10.0 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFH43584.1 - 0.016 14.8 3.3 1.3 8.7 0.1 4.2 3 1 1 4 4 4 0 TPR repeat TPR_6 PF13174.1 KFH43584.1 - 0.02 15.3 8.0 11 6.6 0.0 6.3 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFH43584.1 - 0.024 15.2 14.4 0.24 12.1 0.2 5.6 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFH43584.1 - 0.025 15.2 10.5 2.8 8.7 0.0 5.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 KFH43584.1 - 0.12 12.5 0.9 0.53 10.4 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFH43584.1 - 1.1 9.6 13.5 4.7 7.6 0.0 6.1 7 1 0 7 7 7 0 Tetratricopeptide repeat CBP4 PF07960.6 KFH43585.1 - 4.1e-32 110.4 0.5 4.8e-32 110.2 0.4 1.1 1 0 0 1 1 1 1 CBP4 DUF4207 PF13904.1 KFH43585.1 - 0.63 9.3 9.1 0.77 9.0 6.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4207) DASH_Hsk3 PF08227.6 KFH43586.1 - 7.7e-22 77.2 5.1 9.8e-22 76.8 3.5 1.1 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like Mating_C PF12737.2 KFH43586.1 - 0.0052 15.7 0.8 0.0058 15.5 0.6 1.1 1 0 0 1 1 1 1 C-terminal domain of homeodomain 1 MRP-L28 PF09812.4 KFH43586.1 - 0.08 12.7 0.1 0.085 12.6 0.1 1.0 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 YPEB PF14620.1 KFH43586.1 - 0.11 11.4 0.1 0.12 11.4 0.1 1.0 1 0 0 1 1 1 0 YpeB sporulation A_deamin PF02137.13 KFH43587.1 - 7.8e-58 196.4 0.0 9.6e-58 196.1 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain TRI12 PF06609.8 KFH43588.1 - 1.5e-45 155.5 14.7 1.8e-45 155.2 10.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KFH43588.1 - 4.1e-19 68.5 38.2 4.1e-19 68.5 26.5 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH43588.1 - 8.8e-06 24.5 8.2 8.8e-06 24.5 5.7 3.3 2 1 1 3 3 3 2 Sugar (and other) transporter Peptidase_M24 PF00557.19 KFH43589.1 - 1.1e-44 152.5 0.1 1.4e-44 152.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Band_7 PF01145.20 KFH43590.1 - 3.4e-24 85.7 3.1 4.7e-24 85.2 2.1 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family E_Pc_C PF06752.7 KFH43590.1 - 0.004 16.6 0.1 0.0063 16.0 0.1 1.4 1 0 0 1 1 1 1 Enhancer of Polycomb C-terminus Methyltransf_31 PF13847.1 KFH43591.1 - 1.3e-10 41.0 0.1 2e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFH43591.1 - 1.5e-10 40.6 0.0 2.3e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PRMT5 PF05185.11 KFH43591.1 - 1.9e-10 40.2 0.1 2.4e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_18 PF12847.2 KFH43591.1 - 1.2e-07 32.2 0.0 2.5e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFH43591.1 - 3.5e-07 30.2 0.0 7.2e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH43591.1 - 1.3e-06 28.7 0.0 2.5e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KFH43591.1 - 1.8e-06 26.9 0.1 2.7e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 KFH43591.1 - 7.8e-06 26.1 0.0 2.8e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH43591.1 - 0.00016 21.4 0.0 0.00027 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFH43591.1 - 0.00023 20.5 0.5 0.0005 19.4 0.1 1.6 1 1 1 2 2 2 1 Methyltransferase small domain CMAS PF02353.15 KFH43591.1 - 0.00059 19.0 0.0 0.00083 18.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 KFH43591.1 - 0.0021 18.5 0.0 0.0045 17.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KFH43591.1 - 0.012 15.3 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 KFH43591.1 - 0.091 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PCMT PF01135.14 KFH43591.1 - 0.11 12.0 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TPT PF03151.11 KFH43592.1 - 2e-30 105.4 9.2 2e-30 105.4 6.4 2.3 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KFH43592.1 - 1.8e-05 23.8 15.0 1.8e-05 23.8 10.4 1.6 2 0 0 2 2 2 1 UAA transporter family EamA PF00892.15 KFH43592.1 - 0.0033 17.4 4.2 0.0033 17.4 2.9 3.3 3 1 0 3 3 3 2 EamA-like transporter family Ribosomal_S6e PF01092.14 KFH43592.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S6e Myc_N PF01056.13 KFH43592.1 - 1.7 7.7 5.9 0.14 11.2 0.4 1.9 2 0 0 2 2 2 0 Myc amino-terminal region ELH PF02323.10 KFH43593.1 - 0.12 11.5 1.0 0.13 11.3 0.7 1.0 1 0 0 1 1 1 0 Egg-laying hormone precursor HLH PF00010.21 KFH43594.1 - 2e-13 49.8 0.6 4.5e-13 48.6 0.4 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SUI1 PF01253.17 KFH43596.1 - 1.4e-18 66.4 0.7 2.7e-18 65.5 0.3 1.7 1 1 0 1 1 1 1 Translation initiation factor SUI1 Pkinase PF00069.20 KFH43597.1 - 1e-43 149.3 0.0 1.6e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH43597.1 - 2e-18 66.3 0.0 3.1e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH43597.1 - 0.0012 17.9 0.0 0.0043 16.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 KFH43597.1 - 0.11 11.8 0.1 0.41 9.9 0.0 1.9 1 1 1 2 2 2 0 RIO1 family DUF1765 PF08578.5 KFH43598.1 - 2.9e-46 156.6 4.1 6.4e-46 155.5 2.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) DUF1180 PF06679.7 KFH43599.1 - 0.0021 17.9 0.2 0.0021 17.9 0.1 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF1180) DUF1191 PF06697.7 KFH43599.1 - 0.032 13.0 0.0 0.046 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) EphA2_TM PF14575.1 KFH43599.1 - 0.055 13.8 0.0 0.096 13.0 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.5 KFH43599.1 - 0.72 9.2 2.9 2 7.7 2.0 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Zn_clus PF00172.13 KFH43600.1 - 0.014 15.2 7.9 0.014 15.2 5.5 2.5 2 1 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain 4HBT PF03061.17 KFH43601.1 - 7.3e-07 29.2 0.0 1.8e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Thioesterase superfamily DUF2413 PF10310.4 KFH43601.1 - 0.026 13.3 0.6 0.044 12.5 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF479 PF04336.7 KFH43601.1 - 0.08 13.0 1.7 0.79 9.8 0.3 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF479 VWA_2 PF13519.1 KFH43602.1 - 9.9e-15 55.0 0.0 1.4e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 KFH43602.1 - 7.6e-09 35.4 0.0 1.1e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.23 KFH43602.1 - 9.4e-09 35.2 0.2 1.3e-08 34.7 0.2 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 KFH43602.1 - 0.0018 17.6 2.0 0.0018 17.6 1.4 2.3 2 0 0 2 2 2 1 Ubiquitin interaction motif DUF243 PF03103.12 KFH43602.1 - 0.013 15.5 0.3 0.013 15.5 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF243) Dynein_heavy PF03028.10 KFH43602.1 - 0.061 11.3 0.1 0.095 10.7 0.0 1.3 1 0 0 1 1 1 0 Dynein heavy chain and region D6 of dynein motor ERCC4 PF02732.10 KFH43603.1 - 1.3e-31 109.2 0.1 2.1e-31 108.6 0.1 1.3 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 KFH43603.1 - 0.00019 21.5 0.0 0.00047 20.2 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.1 KFH43603.1 - 0.0043 17.1 0.0 0.015 15.4 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain Peptidase_M15_3 PF08291.6 KFH43604.1 - 3.7e-27 94.2 0.0 5.2e-27 93.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase M15 PG_binding_1 PF01471.13 KFH43604.1 - 1.1e-13 50.8 0.2 1.8e-13 50.2 0.2 1.4 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Peptidase_M15_2 PF05951.8 KFH43604.1 - 0.015 14.7 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) Extensin-like_C PF06904.7 KFH43604.1 - 0.047 13.4 1.4 4.2 7.0 0.6 2.2 1 1 1 2 2 2 0 Extensin-like protein C-terminus Peptidase_M15_4 PF13539.1 KFH43604.1 - 0.071 13.5 0.2 0.22 11.9 0.1 1.9 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase VanY PF02557.12 KFH43604.1 - 0.082 12.7 0.2 0.7 9.7 0.1 2.1 1 1 1 2 2 2 0 D-alanyl-D-alanine carboxypeptidase PG_binding_3 PF09374.5 KFH43604.1 - 0.22 11.5 1.3 0.87 9.6 0.1 2.2 1 1 1 2 2 2 0 Predicted Peptidoglycan domain Lum_binding PF00677.12 KFH43605.1 - 3.3e-40 135.8 0.5 6.2e-21 74.1 0.1 2.1 2 0 0 2 2 2 2 Lumazine binding domain Bromo_TP PF07524.8 KFH43606.1 - 1.2e-07 31.3 0.0 4.3e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 Bromodomain associated HlyIII PF03006.15 KFH43607.1 - 5.2e-30 104.5 19.1 7.3e-30 104.0 13.2 1.2 1 0 0 1 1 1 1 Haemolysin-III related DUF4149 PF13664.1 KFH43607.1 - 0.023 14.7 2.7 0.071 13.1 1.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) RWD PF05773.17 KFH43608.1 - 1.9e-24 85.7 0.2 3.1e-24 85.0 0.1 1.3 1 0 0 1 1 1 1 RWD domain UQ_con PF00179.21 KFH43608.1 - 0.0036 16.7 0.3 0.0054 16.1 0.2 1.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFH43608.1 - 0.034 13.8 0.2 0.095 12.4 0.1 1.9 1 1 0 1 1 1 0 Prokaryotic E2 family B KfrA_N PF11740.3 KFH43608.1 - 0.69 10.3 10.0 4.1 7.8 3.3 2.4 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term RTC PF01137.16 KFH43609.1 - 4.5e-32 110.6 0.1 6.3e-32 110.1 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 KFH43609.1 - 2.4e-30 104.5 0.1 4.3e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain G-patch PF01585.18 KFH43610.1 - 1.9e-05 24.3 0.0 5e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 G-patch domain DUF4604 PF15377.1 KFH43610.1 - 0.0047 17.1 17.8 0.0047 17.1 12.3 3.3 1 1 2 3 3 3 1 Domain of unknown function (DUF4604) MIP-T3 PF10243.4 KFH43610.1 - 1.2 7.5 72.3 1.6 7.0 50.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF3439 PF11921.3 KFH43610.1 - 1.3 8.7 12.2 2.4 7.9 7.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3439) DUF936 PF06075.7 KFH43610.1 - 1.9 7.2 34.7 2.4 6.9 24.1 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Peptidase_S9 PF00326.16 KFH43611.1 - 3.7e-58 196.2 0.1 1.2e-57 194.6 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFH43611.1 - 9.8e-14 51.3 0.0 1.7e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFH43611.1 - 2.2e-11 44.0 0.1 5e-11 42.9 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family PD40 PF07676.7 KFH43611.1 - 0.00014 21.4 0.0 0.00081 18.9 0.0 2.4 1 0 0 1 1 1 1 WD40-like Beta Propeller Repeat AXE1 PF05448.7 KFH43611.1 - 0.0094 14.4 0.0 0.15 10.5 0.0 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 KFH43611.1 - 0.052 13.1 0.0 0.43 10.1 0.0 2.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF2920 PF11144.3 KFH43611.1 - 0.19 10.7 0.0 6.1 5.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) SWI-SNF_Ssr4 PF08549.5 KFH43612.1 - 9e-180 599.2 19.2 1.6e-179 598.4 13.3 1.4 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1750) Metal_resist PF13801.1 KFH43612.1 - 0.0014 18.5 1.6 0.024 14.6 0.0 2.6 2 0 0 2 2 2 1 Heavy-metal resistance PhoD PF09423.5 KFH43613.1 - 1.2e-08 34.0 0.1 1.2e-06 27.4 0.1 2.3 2 1 0 2 2 2 2 PhoD-like phosphatase DUF4187 PF13821.1 KFH43614.1 - 2.6e-22 78.1 0.1 7e-22 76.7 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) DUF3546 PF12066.3 KFH43614.1 - 4.9e-21 74.8 2.9 4.9e-21 74.8 2.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 KFH43614.1 - 2.1e-12 47.7 0.5 5.4e-12 46.3 0.3 1.7 1 0 0 1 1 1 1 Arsenite-resistance protein 2 Ribosomal_L21p PF00829.16 KFH43615.1 - 0.1 12.7 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal prokaryotic L21 protein HAD PF12710.2 KFH43616.1 - 2.4e-17 63.7 0.0 3.1e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KFH43616.1 - 0.0079 16.4 0.5 0.023 14.9 0.2 1.9 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Ribosomal_S8e PF01201.17 KFH43617.1 - 3e-29 101.8 4.6 1.9e-28 99.2 3.2 1.9 1 1 0 1 1 1 1 Ribosomal protein S8e DUF2390 PF09523.5 KFH43617.1 - 7.8 6.7 6.9 15 5.7 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) Elongin_A PF06881.6 KFH43618.1 - 1.8e-17 63.6 0.6 2.9e-17 63.0 0.4 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A MOSC_N PF03476.11 KFH43619.1 - 9.6e-22 76.9 0.0 1.8e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 KFH43619.1 - 1.9e-21 75.9 0.0 3.5e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 MOSC domain Aminotran_5 PF00266.14 KFH43619.1 - 3.6e-16 58.8 0.0 2.9e-15 55.8 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Aldedh PF00171.17 KFH43620.1 - 7e-105 351.0 0.0 8.8e-105 350.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KFH43620.1 - 0.094 11.4 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) RRM_1 PF00076.17 KFH43621.1 - 8.7e-19 66.9 0.0 1.4e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH43621.1 - 9.6e-12 44.7 0.0 1.6e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH43621.1 - 4.3e-06 26.4 0.0 6.4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tafi-CsgC PF10610.4 KFH43621.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Thin aggregative fimbriae synthesis protein Methyltransf_11 PF08241.7 KFH43622.1 - 1.8e-12 47.5 0.0 4.8e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH43622.1 - 4.2e-05 23.3 0.0 9.9e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFH43622.1 - 0.01 16.2 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KFH43622.1 - 0.018 15.5 0.0 0.076 13.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.13 KFH43622.1 - 0.18 10.9 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Per1 PF04080.8 KFH43623.1 - 7.5e-108 359.9 10.9 9.1e-108 359.7 7.6 1.1 1 0 0 1 1 1 1 Per1-like DUF3522 PF12036.3 KFH43623.1 - 5.8 6.6 12.8 60 3.3 8.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3522) Glyco_hydro_15 PF00723.16 KFH43624.1 - 5.5e-47 160.3 0.0 6.7e-43 146.8 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 CorA PF01544.13 KFH43625.1 - 3.7e-05 22.9 0.0 0.00017 20.7 0.0 2.1 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein RNA_pol_Rpb4 PF03874.11 KFH43626.1 - 1.5e-28 99.1 4.1 1.8e-28 98.8 2.8 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Spexin PF15171.1 KFH43626.1 - 0.0079 16.1 0.3 0.02 14.8 0.2 1.6 1 0 0 1 1 1 1 Neuropeptide secretory protein family, NPQ, spexin GFA PF04828.9 KFH43627.1 - 6.6e-13 48.4 1.7 1.3e-06 28.2 0.5 2.2 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Nbl1_Borealin_N PF10444.4 KFH43628.1 - 1.4e-19 69.1 8.4 1.6e-19 68.9 4.2 2.0 2 0 0 2 2 2 1 Nbl1 / Borealin N terminal Coleoptericin PF06286.6 KFH43628.1 - 5 7.0 7.4 0.35 10.7 0.3 2.4 1 1 0 2 2 2 0 Coleoptericin PGM_PMM_I PF02878.11 KFH43629.1 - 7.9e-18 64.2 0.0 4.3e-08 32.7 0.0 2.7 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.15 KFH43629.1 - 2.6e-12 46.5 0.2 8.8e-12 44.8 0.1 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.11 KFH43629.1 - 1.3e-09 38.3 0.0 5.2e-09 36.3 0.0 2.1 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II HTH_31 PF13560.1 KFH43629.1 - 0.021 15.0 0.1 0.1 12.8 0.0 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain PGM_PMM_III PF02880.11 KFH43629.1 - 0.035 14.1 0.0 0.083 12.9 0.0 1.7 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DUF3632 PF12311.3 KFH43630.1 - 5.8e-14 52.3 0.1 9.5e-10 38.5 0.2 2.8 1 1 1 2 2 2 2 Protein of unknown function (DUF3632) DUF1049 PF06305.6 KFH43631.1 - 0.16 11.5 0.4 0.54 9.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) TPR_12 PF13424.1 KFH43632.1 - 1.2e-16 60.3 0.0 2e-09 37.2 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFH43632.1 - 6.6e-13 48.9 3.2 5e-06 27.0 0.0 4.1 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFH43632.1 - 1.3e-12 46.6 0.1 0.00021 20.9 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFH43632.1 - 2.9e-12 46.7 1.0 1.6e-05 25.1 0.0 3.9 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFH43632.1 - 8.9e-12 44.4 0.1 3.7e-05 23.2 0.0 3.8 3 1 2 5 5 5 3 TPR repeat TPR_14 PF13428.1 KFH43632.1 - 2.2e-10 40.2 10.4 0.046 14.3 0.0 5.7 5 2 1 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFH43632.1 - 3e-10 39.0 1.1 0.001 18.6 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 KFH43632.1 - 1.3e-08 34.4 4.1 0.0099 15.7 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 KFH43632.1 - 1.4e-08 33.9 0.0 0.01 15.4 0.0 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.1 KFH43632.1 - 0.00024 21.3 5.7 2.4 8.7 0.0 5.4 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFH43632.1 - 0.00028 20.4 0.0 0.16 11.8 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFH43632.1 - 0.0031 17.5 0.0 52 4.4 0.0 4.8 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 KFH43632.1 - 0.0035 17.1 2.1 5.6 6.8 0.0 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 KFH43632.1 - 0.0055 16.8 0.0 3 8.0 0.0 2.9 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 PapC_C PF13953.1 KFH43632.1 - 0.053 13.1 0.1 3.6 7.3 0.0 2.7 2 1 0 2 2 2 0 PapC C-terminal domain Med11 PF10280.4 KFH43632.1 - 0.054 13.5 0.1 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Mediator complex protein ChAPs PF09295.5 KFH43632.1 - 0.34 9.6 1.8 3.4 6.3 0.2 2.2 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_21 PF09976.4 KFH43632.1 - 0.66 9.9 7.8 7.7 6.4 0.0 3.4 3 1 1 4 4 3 0 Tetratricopeptide repeat DUF4363 PF14276.1 KFH43632.1 - 2.3 7.9 4.0 25 4.6 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) TPR_4 PF07721.9 KFH43632.1 - 4.6 7.9 12.1 3 8.5 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF1746 PF08508.5 KFH43634.1 - 1.4e-25 89.5 0.4 5.2e-24 84.4 0.1 2.2 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1746) CPL PF08144.6 KFH43635.1 - 7.5e-18 64.7 0.2 2.1e-16 60.0 0.0 3.1 2 1 1 3 3 3 1 CPL (NUC119) domain RasGAP PF00616.14 KFH43635.1 - 0.057 13.0 0.3 2.5 7.7 0.0 2.7 3 0 0 3 3 3 0 GTPase-activator protein for Ras-like GTPase PPR_2 PF13041.1 KFH43636.1 - 1.4e-12 47.3 0.3 5.1e-08 32.7 0.0 5.0 5 0 0 5 5 5 1 PPR repeat family PPR PF01535.15 KFH43636.1 - 0.00015 21.4 0.3 2 8.5 0.0 4.6 4 0 0 4 4 4 1 PPR repeat PPR_3 PF13812.1 KFH43636.1 - 0.00057 19.9 5.3 95 3.6 0.0 7.1 7 0 0 7 7 7 0 Pentatricopeptide repeat domain TPR_19 PF14559.1 KFH43636.1 - 0.0096 16.2 1.2 3 8.2 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFH43636.1 - 0.038 14.6 2.8 20 6.1 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR_1 PF12854.2 KFH43636.1 - 0.1 12.0 2.1 30 4.1 0.1 4.2 5 0 0 5 5 5 0 PPR repeat TPR_6 PF13174.1 KFH43636.1 - 3.1 8.4 4.9 16 6.2 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2949 PF11165.3 KFH43637.1 - 0.098 12.8 0.1 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2949) Lambda_Kil PF06301.6 KFH43637.1 - 0.12 11.8 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage lambda Kil protein tRNA-synt_2d PF01409.15 KFH43638.1 - 4e-85 284.9 0.0 5.3e-85 284.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 KFH43638.1 - 9.7e-06 24.5 0.2 0.00029 19.7 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 KFH43638.1 - 0.0004 20.0 0.0 0.0041 16.7 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) 6PGD PF00393.14 KFH43639.1 - 7e-135 448.8 0.0 8.8e-135 448.5 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KFH43639.1 - 6e-51 172.5 0.0 9e-51 171.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KFH43639.1 - 0.074 13.1 0.0 0.24 11.4 0.0 1.9 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 KFH43639.1 - 0.12 12.4 0.1 0.35 10.9 0.0 1.8 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 KFH43639.1 - 0.17 11.5 0.5 12 5.5 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TFIIF_beta PF02270.10 KFH43642.1 - 3.4e-66 223.8 0.4 4.3e-66 223.5 0.3 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit CENP-B_dimeris PF09026.5 KFH43642.1 - 5 7.4 8.4 1.9e+02 2.3 6.2 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain GCV_H PF01597.14 KFH43643.1 - 8.1e-33 112.6 1.2 9.7e-33 112.4 0.8 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 KFH43643.1 - 0.086 12.4 0.1 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Biotin-requiring enzyme PLDc_2 PF13091.1 KFH43644.1 - 2.3e-14 53.2 0.0 1.3e-07 31.3 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KFH43644.1 - 4.8e-08 32.5 0.2 0.00063 19.4 0.0 2.8 2 1 0 2 2 2 2 Phospholipase D Active site motif FA PF08736.6 KFH43644.1 - 0.11 12.3 0.1 0.6 9.9 0.0 2.2 2 0 0 2 2 2 0 FERM adjacent (FA) CRAL_TRIO PF00650.15 KFH43645.1 - 6.3e-38 129.7 0.0 8e-38 129.4 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KFH43645.1 - 8.5e-11 41.8 0.1 2.1e-10 40.5 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KFH43645.1 - 0.026 14.4 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain PNTB PF02233.11 KFH43646.1 - 2.6e-167 557.2 22.5 2.6e-167 557.2 15.6 1.5 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 KFH43646.1 - 1.5e-52 177.5 0.6 3.2e-52 176.4 0.4 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 KFH43646.1 - 5.4e-50 168.9 0.2 1.2e-49 167.7 0.1 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 KFH43646.1 - 2.4e-31 107.7 3.0 2.4e-31 107.7 2.0 4.8 4 2 3 7 7 6 1 Domain of unknown function (DUF3814) ADH_zinc_N PF00107.21 KFH43646.1 - 0.00065 19.2 0.3 0.0025 17.3 0.2 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KFH43646.1 - 0.00076 18.6 0.0 0.74 8.9 0.0 2.7 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 KFH43646.1 - 0.0042 17.6 0.0 0.042 14.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Pyr_redox_2 PF07992.9 KFH43646.1 - 0.0084 16.0 0.1 0.028 14.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fumerase PF05681.9 KFH43646.1 - 0.033 13.2 0.0 0.059 12.4 0.0 1.3 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) CP_ATPgrasp_1 PF04174.8 KFH43646.1 - 0.071 11.7 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 A circularly permuted ATPgrasp Methyltransf_31 PF13847.1 KFH43646.1 - 0.072 12.6 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Git3 PF11710.3 KFH43646.1 - 0.17 11.4 0.1 0.35 10.3 0.1 1.4 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 NAD_binding_8 PF13450.1 KFH43646.1 - 1 9.4 8.0 0.11 12.4 0.2 3.0 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Peptidase_S24 PF00717.18 KFH43647.1 - 2.6e-08 33.3 0.0 3.9e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 KFH43647.1 - 1.1e-05 25.0 0.0 0.00013 21.5 0.0 2.3 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Alpha-L-AF_C PF06964.7 KFH43648.1 - 1.4e-26 93.3 0.0 2e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Orn_Arg_deC_N PF02784.11 KFH43649.1 - 2.3e-77 259.5 0.0 3.1e-77 259.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 KFH43649.1 - 3.5e-30 104.0 0.0 6e-30 103.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Arm PF00514.18 KFH43650.1 - 2e-71 233.5 33.3 1.5e-13 50.0 0.1 11.0 11 0 0 11 11 11 10 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFH43650.1 - 6.1e-24 84.1 12.3 1.8e-07 31.3 0.2 7.6 2 2 3 6 6 6 5 HEAT repeats HEAT PF02985.17 KFH43650.1 - 9.5e-19 65.7 16.3 0.016 15.2 0.0 9.5 10 0 0 10 10 10 5 HEAT repeat HEAT_EZ PF13513.1 KFH43650.1 - 2e-16 59.9 13.0 0.00025 21.4 0.2 8.6 5 1 4 9 9 9 4 HEAT-like repeat Adaptin_N PF01602.15 KFH43650.1 - 7.6e-13 47.6 6.9 1.8e-07 29.8 0.2 2.4 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.8 KFH43650.1 - 2e-11 43.5 8.1 0.00073 18.7 0.6 3.4 2 1 1 3 3 3 3 Armadillo-like V-ATPase_H_N PF03224.9 KFH43650.1 - 2.4e-09 36.7 1.8 5.8e-05 22.3 0.6 3.6 2 1 1 3 3 3 2 V-ATPase subunit H KAP PF05804.7 KFH43650.1 - 2.5e-09 35.6 1.4 4.9e-09 34.6 1.0 1.5 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) DUF908 PF06012.7 KFH43650.1 - 0.00028 20.3 2.3 0.84 8.8 0.1 3.9 2 1 0 3 3 3 2 Domain of Unknown Function (DUF908) DUF2454 PF10521.4 KFH43650.1 - 0.0008 18.4 0.5 0.0089 15.0 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2454) PUL PF08324.6 KFH43650.1 - 0.012 14.4 0.5 0.048 12.4 0.4 2.1 1 0 0 1 1 1 0 PUL domain HEAT_PBS PF03130.11 KFH43650.1 - 0.016 15.6 7.7 28 5.5 0.1 6.8 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.2 KFH43650.1 - 0.031 14.6 0.2 3.8 7.9 0.0 3.5 2 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region PI-PLC-X PF00388.14 KFH43651.1 - 1.1e-54 183.7 0.0 2.1e-54 182.8 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KFH43651.1 - 1.7e-38 131.2 0.1 3.8e-38 130.0 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KFH43651.1 - 4.1e-05 23.5 0.1 0.0031 17.4 0.0 2.7 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_7 PF13499.1 KFH43651.1 - 0.029 14.4 0.1 0.33 11.1 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_8 PF13833.1 KFH43651.1 - 0.13 11.8 0.1 11 5.7 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair DUF3375 PF11855.3 KFH43651.1 - 0.57 8.8 4.7 0.091 11.4 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3375) Peptidase_M48 PF01435.13 KFH43653.1 - 1e-48 165.8 0.0 1.6e-48 165.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 ClpS PF02617.12 KFH43653.1 - 0.0089 15.7 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Peptidase_M56 PF05569.6 KFH43653.1 - 0.095 11.6 0.0 0.23 10.4 0.0 1.7 2 0 0 2 2 2 0 BlaR1 peptidase M56 DUF2201_N PF13203.1 KFH43653.1 - 0.3 10.2 0.5 0.65 9.1 0.1 1.7 2 0 0 2 2 2 0 Putative metallopeptidase domain p450 PF00067.17 KFH43654.1 - 1.8e-22 79.5 0.4 2.9e-22 78.8 0.2 1.3 1 1 1 2 2 2 1 Cytochrome P450 CBS PF00571.23 KFH43655.1 - 4.8e-32 109.4 6.8 1.2e-12 47.3 0.1 4.3 4 0 0 4 4 4 4 CBS domain B56 PF01603.15 KFH43656.1 - 4e-174 579.0 4.9 4.8e-174 578.7 3.4 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.2 KFH43656.1 - 0.013 14.9 1.5 1.2 8.5 0.2 2.7 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal TRAPP PF04051.11 KFH43657.1 - 4.9e-39 133.2 0.0 5.7e-39 133.0 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Tau95 PF09734.4 KFH43658.1 - 8.1e-66 222.4 0.0 1e-65 222.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH_32 PF13565.1 KFH43658.1 - 0.072 13.8 0.0 0.28 12.0 0.0 2.0 1 0 0 1 1 1 0 Homeodomain-like domain Zn_clus PF00172.13 KFH43659.1 - 0.1 12.5 14.7 0.41 10.5 10.2 2.0 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KFH43660.1 - 3.7e-21 75.2 9.4 4.1e-21 75.0 6.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.8 KFH43660.1 - 7.3e-05 21.0 2.2 7.5e-05 21.0 1.5 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector Sugar_tr PF00083.19 KFH43660.1 - 0.00066 18.3 3.9 0.00069 18.3 2.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 KFH43660.1 - 0.022 12.8 0.6 0.024 12.7 0.4 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Lebercilin PF15619.1 KFH43661.1 - 0.0045 16.4 1.5 0.0076 15.6 1.0 1.3 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease DUF4546 PF15079.1 KFH43661.1 - 0.036 13.2 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4546) Kinetocho_Slk19 PF12709.2 KFH43661.1 - 0.061 13.3 0.1 0.15 12.1 0.1 1.7 1 0 0 1 1 1 0 Central kinetochore-associated Bap31 PF05529.7 KFH43661.1 - 0.26 10.7 0.8 0.43 10.0 0.6 1.4 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like TPR_MLP1_2 PF07926.7 KFH43661.1 - 0.35 10.6 4.5 0.65 9.7 3.1 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein CTD_bind PF04818.8 KFH43662.1 - 8e-09 35.6 0.0 1.6e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF4407 PF14362.1 KFH43662.1 - 0.44 9.4 2.1 0.8 8.6 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) p450 PF00067.17 KFH43663.1 - 0.00042 18.9 0.0 0.00042 18.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MtrF PF09472.5 KFH43665.1 - 0.00042 19.4 0.2 0.0007 18.7 0.1 1.4 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Podoplanin PF05808.6 KFH43665.1 - 0.019 14.5 4.5 1.9 8.0 0.0 2.2 1 1 1 2 2 2 0 Podoplanin DUF1191 PF06697.7 KFH43665.1 - 0.032 13.0 0.1 0.037 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Shisa PF13908.1 KFH43665.1 - 0.095 12.8 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator APH PF01636.18 KFH43666.1 - 2.1e-16 60.4 0.4 7.7e-16 58.5 0.3 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 KFH43666.1 - 0.054 12.4 0.0 0.11 11.4 0.0 1.5 2 0 0 2 2 2 0 Fructosamine kinase Ras PF00071.17 KFH43667.1 - 1.1e-31 109.3 0.1 1.4e-31 109.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFH43667.1 - 3.4e-21 75.9 0.1 2.1e-20 73.3 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFH43667.1 - 1.2e-06 27.8 0.0 1.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFH43667.1 - 8.5e-05 21.7 0.1 0.00011 21.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFH43667.1 - 0.052 13.4 0.0 0.095 12.6 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.15 KFH43667.1 - 0.082 11.5 0.0 0.12 10.9 0.0 1.5 1 0 0 1 1 1 0 G-protein alpha subunit Apc13p PF05839.6 KFH43668.1 - 1.2e-29 102.0 0.1 1.4e-29 101.9 0.1 1.0 1 0 0 1 1 1 1 Apc13p protein Porphobil_deam PF01379.15 KFH43669.1 - 3.6e-75 251.5 0.0 5.4e-75 250.9 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 KFH43669.1 - 2e-20 72.6 0.2 4.2e-20 71.6 0.1 1.6 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain BCS1_N PF08740.6 KFH43670.1 - 2e-43 148.1 5.5 2e-43 148.1 3.8 2.3 2 0 0 2 2 1 1 BCS1 N terminal AAA PF00004.24 KFH43670.1 - 2.8e-17 63.1 0.0 1.4e-08 34.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) SR-25 PF10500.4 KFH43670.1 - 2.5e-05 23.8 29.2 6.6e-05 22.4 20.2 1.7 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein AAA_17 PF13207.1 KFH43670.1 - 0.0002 22.1 0.7 0.00075 20.3 0.1 2.4 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KFH43670.1 - 0.0022 17.1 0.0 0.0037 16.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 KFH43670.1 - 0.0069 15.8 0.0 0.016 14.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFH43670.1 - 0.022 14.6 0.0 0.084 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 KFH43670.1 - 0.11 11.6 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.1 KFH43670.1 - 0.16 11.7 1.0 1.4 8.7 0.1 2.4 2 0 0 2 2 2 0 Part of AAA domain FAM60A PF15396.1 KFH43670.1 - 0.36 10.5 16.5 0.83 9.3 11.5 1.6 1 0 0 1 1 1 0 Protein Family FAM60A Cwf_Cwc_15 PF04889.7 KFH43670.1 - 0.62 9.7 25.8 1.7 8.3 17.9 1.7 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3827 PF12877.2 KFH43670.1 - 5.9 4.8 16.5 9 4.2 11.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Macoilin PF09726.4 KFH43670.1 - 9.1 4.4 18.5 14 3.7 12.8 1.2 1 0 0 1 1 1 0 Transmembrane protein NDUFA12 PF05071.11 KFH43671.1 - 1.7e-21 76.6 0.0 2e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PBP1_TM PF14812.1 KFH43672.1 - 0.015 15.5 10.9 0.078 13.2 1.6 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 KFH43672.1 - 0.87 9.0 7.5 1.2 8.6 0.1 2.2 2 0 0 2 2 2 0 Nucleoplasmin DUF4611 PF15387.1 KFH43672.1 - 0.97 9.6 11.9 6 7.0 1.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Nucleo_P87 PF07267.6 KFH43672.1 - 2.6 6.6 5.9 4.2 5.9 4.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF3246 PF11596.3 KFH43672.1 - 5.3 6.2 17.0 1.9 7.7 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3246) zf-DHHC PF01529.15 KFH43674.1 - 1.2e-43 148.5 6.1 1.2e-43 148.5 4.2 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase DZR PF12773.2 KFH43674.1 - 0.075 12.8 6.3 0.14 11.9 4.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon Zw10 PF06248.8 KFH43675.1 - 4.2e-14 51.6 2.0 7.3e-10 37.6 0.3 2.9 2 1 1 3 3 3 2 Centromere/kinetochore Zw10 MutS_III PF05192.13 KFH43675.1 - 0.051 13.3 0.1 0.55 9.9 0.0 2.6 1 1 0 1 1 1 0 MutS domain III TetR_C_2 PF08361.6 KFH43675.1 - 0.091 12.6 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 MAATS-type transcriptional repressor, C-terminal region Dsl1_C PF11989.3 KFH43675.1 - 0.59 9.2 5.2 3.1 6.8 0.0 3.2 3 0 0 3 3 3 0 Retrograde transport protein Dsl1 C terminal Nop14 PF04147.7 KFH43675.1 - 0.62 7.9 10.4 1.1 7.1 7.2 1.3 1 0 0 1 1 1 0 Nop14-like family Zn_clus PF00172.13 KFH43676.1 - 0.00014 21.6 4.7 0.00034 20.4 3.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DSHCT PF08148.7 KFH43676.1 - 0.024 13.8 0.0 0.085 12.0 0.0 1.9 2 0 0 2 2 2 0 DSHCT (NUC185) domain Taxilin PF09728.4 KFH43677.1 - 7.6e-84 281.4 56.0 7.6e-84 281.4 38.8 1.3 2 0 0 2 2 2 1 Myosin-like coiled-coil protein DUF904 PF06005.7 KFH43677.1 - 0.024 14.9 9.0 0.024 14.9 6.3 5.4 3 1 1 4 4 4 0 Protein of unknown function (DUF904) NPV_P10 PF05531.7 KFH43677.1 - 2.9 8.2 8.7 5.3 7.3 0.9 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Rep_fac-A_3 PF08661.6 KFH43678.1 - 1.3e-19 70.0 0.0 1.5e-16 60.2 0.0 2.0 1 1 1 2 2 2 2 Replication factor A protein 3 Herpes_gI PF01688.12 KFH43678.1 - 0.016 14.3 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein I zf-C2H2 PF00096.21 KFH43679.1 - 4.2e-13 48.7 12.6 0.0026 18.0 0.0 5.5 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFH43679.1 - 2.2e-10 40.0 9.8 0.16 12.3 0.2 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFH43679.1 - 5.6e-07 29.2 10.6 0.0024 17.7 0.1 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFH43679.1 - 1e-06 28.7 4.9 0.38 10.9 0.1 4.7 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 KFH43679.1 - 0.00014 21.9 11.3 0.095 12.8 0.2 4.6 4 1 0 4 4 4 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 KFH43679.1 - 0.0002 21.4 7.5 0.45 10.6 0.0 4.4 2 2 1 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KFH43679.1 - 0.00032 20.7 6.8 0.2 11.8 0.3 4.1 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 KFH43679.1 - 0.0066 16.6 1.2 0.0066 16.6 0.8 5.5 5 0 0 5 5 5 1 Zinc-finger double domain Elf1 PF05129.8 KFH43679.1 - 0.32 10.7 10.9 0.27 10.9 0.7 3.8 3 1 1 4 4 4 0 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.5 KFH43679.1 - 3.5 7.6 17.0 1.4 8.9 0.1 4.7 4 1 0 4 4 4 0 Zinc ribbon domain Exo_endo_phos PF03372.18 KFH43681.1 - 3.3e-27 96.0 0.2 5.6e-27 95.2 0.2 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 KFH43681.1 - 0.00031 20.4 0.0 0.0012 18.6 0.0 2.2 1 0 0 1 1 1 1 WD domain, G-beta repeat MRF_C1 PF13887.1 KFH43681.1 - 0.19 10.7 0.0 0.49 9.4 0.0 1.6 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 bZIP_1 PF00170.16 KFH43682.1 - 9.8e-12 44.6 11.6 1.7e-11 43.8 8.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFH43682.1 - 2.8e-07 30.2 11.0 2.8e-07 30.2 7.6 2.1 2 1 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFH43682.1 - 5.5e-05 23.3 6.0 5.5e-05 23.3 4.2 2.3 1 1 1 2 2 2 1 bZIP Maf transcription factor Lectin_N PF03954.9 KFH43682.1 - 0.0064 15.9 0.1 0.012 14.9 0.1 1.4 1 0 0 1 1 1 1 Hepatic lectin, N-terminal domain Prefoldin_2 PF01920.15 KFH43682.1 - 0.0092 15.7 1.5 0.018 14.8 1.0 1.4 1 0 0 1 1 1 1 Prefoldin subunit DivIC PF04977.10 KFH43682.1 - 0.14 11.6 2.2 0.31 10.5 1.5 1.5 1 0 0 1 1 1 0 Septum formation initiator CAF-1_p150 PF11600.3 KFH43682.1 - 0.31 10.3 15.7 0.57 9.5 10.9 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3720 PF12517.3 KFH43682.1 - 0.41 11.3 8.3 0.078 13.6 3.1 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF3720) Jnk-SapK_ap_N PF09744.4 KFH43682.1 - 0.51 10.3 9.2 0.78 9.7 6.4 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Uso1_p115_C PF04871.8 KFH43682.1 - 2 8.3 11.5 1.2 9.0 6.7 1.6 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3682 PF12446.3 KFH43682.1 - 3.8 7.8 21.2 0.039 14.2 8.8 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3682) RR_TM4-6 PF06459.7 KFH43682.1 - 6.3 6.6 8.6 9.2 6.0 6.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ribosomal_L4 PF00573.17 KFH43685.1 - 1.3e-45 155.2 0.0 1.8e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Pec_lyase_N PF04431.8 KFH43686.1 - 0.13 12.3 1.0 1.4 9.0 0.1 2.5 3 0 0 3 3 3 0 Pectate lyase, N terminus PBP PF01161.15 KFH43687.1 - 7.4e-10 38.8 0.0 1.2e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF1049 PF06305.6 KFH43688.1 - 0.033 13.6 0.4 0.056 12.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) ADH_zinc_N PF00107.21 KFH43689.1 - 7.6e-19 67.5 0.6 1.2e-18 66.9 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFH43689.1 - 2.8e-08 34.6 0.6 1e-07 32.8 0.0 2.1 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFH43689.1 - 1e-05 25.2 0.0 2.2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 KFH43689.1 - 0.018 15.0 0.3 0.03 14.3 0.2 1.3 1 0 0 1 1 1 0 NADH(P)-binding Glyco_hydro_61 PF03443.9 KFH43691.1 - 1.3e-40 139.5 0.0 1.5e-40 139.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Ribonuc_L-PSP PF01042.16 KFH43693.1 - 1.8e-25 89.0 0.0 2e-25 88.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP ETF_alpha PF00766.14 KFH43693.1 - 0.05 13.2 0.1 0.13 11.9 0.0 1.6 1 1 0 1 1 1 0 Electron transfer flavoprotein FAD-binding domain ORC4_C PF14629.1 KFH43694.1 - 1.6e-56 190.9 0.0 2.3e-56 190.4 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 KFH43694.1 - 5.8e-15 55.7 0.0 9.6e-14 51.7 0.1 2.7 2 1 0 2 2 1 1 AAA ATPase domain PHD_2 PF13831.1 KFH43694.1 - 8.5e-12 44.1 3.9 8.5e-12 44.1 2.7 1.7 2 0 0 2 2 1 1 PHD-finger PHD PF00628.24 KFH43694.1 - 3.6e-10 39.3 7.6 6e-10 38.6 5.3 1.4 1 0 0 1 1 1 1 PHD-finger NACHT PF05729.7 KFH43694.1 - 5.3e-08 32.6 0.0 1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KFH43694.1 - 6.8e-08 32.7 0.0 1.3e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KFH43694.1 - 1.4e-06 28.5 0.0 3.7e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KFH43694.1 - 0.00058 19.6 0.0 0.0015 18.3 0.0 1.6 1 1 0 1 1 1 1 Archaeal ATPase KAP_NTPase PF07693.9 KFH43694.1 - 0.00071 18.6 0.0 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain AAA_14 PF13173.1 KFH43694.1 - 0.00085 19.2 0.0 0.0027 17.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KFH43694.1 - 0.0014 18.0 0.0 0.0032 16.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain C1_1 PF00130.17 KFH43694.1 - 0.0017 18.0 0.8 0.0038 16.9 0.5 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.11 KFH43694.1 - 0.0018 18.1 0.6 0.0034 17.2 0.4 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger DUF815 PF05673.8 KFH43694.1 - 0.0033 16.3 0.0 0.0052 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) cobW PF02492.14 KFH43694.1 - 0.0041 16.5 0.0 0.0069 15.8 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 KFH43694.1 - 0.0043 15.9 0.0 0.006 15.4 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain FtsK_SpoIIIE PF01580.13 KFH43694.1 - 0.0071 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_10 PF12846.2 KFH43694.1 - 0.0075 15.7 0.0 0.42 9.9 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain AAA_19 PF13245.1 KFH43694.1 - 0.015 15.0 0.0 0.039 13.6 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain G-alpha PF00503.15 KFH43694.1 - 0.016 13.9 1.2 0.025 13.2 0.0 1.9 2 1 0 2 2 1 0 G-protein alpha subunit AAA_25 PF13481.1 KFH43694.1 - 0.017 14.5 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 KFH43694.1 - 0.017 14.0 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.22 KFH43694.1 - 0.022 15.0 0.0 0.046 14.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.1 KFH43694.1 - 0.026 14.1 0.0 0.083 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KFH43694.1 - 0.039 14.7 0.0 0.093 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 KFH43694.1 - 0.043 13.5 0.0 0.088 12.5 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.16 KFH43694.1 - 0.052 12.7 0.0 0.096 11.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ORC2 PF04084.9 KFH43694.1 - 0.053 12.3 0.2 0.31 9.8 0.0 1.9 2 0 0 2 2 2 0 Origin recognition complex subunit 2 Pox_A32 PF04665.7 KFH43694.1 - 0.097 11.9 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_33 PF13671.1 KFH43694.1 - 0.11 12.4 0.0 0.36 10.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain TrwB_AAD_bind PF10412.4 KFH43694.1 - 0.11 11.1 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain PIF1 PF05970.9 KFH43694.1 - 0.11 11.3 0.0 0.22 10.4 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase Bac_DnaA PF00308.13 KFH43694.1 - 0.18 11.4 0.0 11 5.6 0.0 2.1 2 0 0 2 2 2 0 Bacterial dnaA protein DUF4611 PF15387.1 KFH43694.1 - 0.44 10.7 3.4 1.4 9.1 2.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DZR PF12773.2 KFH43694.1 - 1.9 8.3 5.5 11 5.9 3.8 2.1 1 1 1 2 2 2 0 Double zinc ribbon MFS_1 PF07690.11 KFH43696.1 - 7.3e-29 100.5 30.1 9.3e-29 100.2 20.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Neurensin PF14927.1 KFH43696.1 - 0.075 12.4 0.0 0.33 10.3 0.0 2.1 2 0 0 2 2 2 0 Neurensin NfeD PF01957.13 KFH43696.1 - 8.1 6.5 14.9 3.4 7.7 0.0 4.1 3 1 2 5 5 5 0 NfeD-like C-terminal, partner-binding LtrA PF06772.6 KFH43697.1 - 3.6e-15 55.7 20.7 6.4e-15 54.9 14.3 1.3 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Sulf_transp PF04143.9 KFH43698.1 - 5.9e-16 58.2 28.3 1.1e-09 38.1 6.0 4.6 4 1 1 5 5 5 2 Sulphur transport DUF4341 PF14241.1 KFH43698.1 - 0.0059 16.2 6.1 0.0059 16.2 4.2 4.9 5 1 0 5 5 5 1 Domain of unknown function (DUF4341) AAA PF00004.24 KFH43699.1 - 6.7e-50 168.6 0.0 1.7e-39 135.0 0.0 2.6 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFH43699.1 - 2.5e-07 30.8 0.0 0.0011 19.0 0.0 3.6 3 1 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 KFH43699.1 - 2.5e-06 27.6 5.8 0.45 10.6 0.0 4.8 3 2 1 4 4 4 3 AAA domain AAA_5 PF07728.9 KFH43699.1 - 4.1e-06 26.5 0.0 0.18 11.5 0.0 3.5 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KFH43699.1 - 2.5e-05 23.9 0.4 0.029 14.1 0.0 4.0 5 1 0 5 5 5 1 Part of AAA domain NACHT PF05729.7 KFH43699.1 - 4.1e-05 23.2 0.5 0.37 10.4 0.1 3.9 3 2 2 5 5 4 1 NACHT domain AAA_25 PF13481.1 KFH43699.1 - 6e-05 22.5 1.7 0.39 10.0 0.0 3.9 2 2 1 3 3 3 1 AAA domain AAA_14 PF13173.1 KFH43699.1 - 9.5e-05 22.3 0.0 0.46 10.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 KFH43699.1 - 0.00026 20.9 0.0 0.0062 16.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KFH43699.1 - 0.00068 18.7 0.0 0.0039 16.2 0.0 2.3 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 KFH43699.1 - 0.0013 18.9 0.0 2.4 8.3 0.0 3.1 3 0 0 3 3 3 2 RNA helicase IstB_IS21 PF01695.12 KFH43699.1 - 0.036 13.4 0.2 3.6 6.9 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.1 KFH43699.1 - 0.068 13.9 0.0 0.42 11.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain Holin_LLH PF09682.5 KFH43699.1 - 0.077 13.1 0.1 0.22 11.6 0.0 1.8 2 0 0 2 2 2 0 Phage holin protein (Holin_LLH) Sigma54_activ_2 PF14532.1 KFH43699.1 - 0.1 12.6 0.0 9.8 6.2 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 KFH43699.1 - 0.12 11.5 0.2 1.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF383 PF04063.9 KFH43700.1 - 3.4e-67 225.7 0.1 1e-66 224.1 0.0 1.9 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.8 KFH43700.1 - 9e-24 82.8 0.6 2.5e-23 81.3 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF384) F-box-like PF12937.2 KFH43701.1 - 2e-06 27.4 0.3 4.5e-06 26.3 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFH43701.1 - 0.0012 18.3 1.4 0.0018 17.9 0.3 1.8 2 0 0 2 2 2 1 F-box domain Acetyltransf_1 PF00583.19 KFH43702.1 - 1.1e-20 73.4 1.2 2.7e-14 52.9 0.1 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KFH43702.1 - 8.2e-10 38.8 0.1 1.8e-05 24.8 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KFH43702.1 - 9.4e-09 35.3 0.0 4.8e-06 26.6 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFH43702.1 - 1.2e-08 34.6 0.2 0.0001 21.9 0.0 2.9 3 1 0 3 3 3 2 FR47-like protein Acetyltransf_3 PF13302.1 KFH43702.1 - 1.4e-07 31.8 1.1 1e-05 25.7 0.1 2.4 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KFH43702.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFH43702.1 - 0.016 15.1 0.1 4.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KFH43702.1 - 0.13 12.1 0.0 0.99 9.2 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KFH43702.1 - 0.15 11.9 0.1 11 6.0 0.0 2.3 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Peptidase_S24 PF00717.18 KFH43704.1 - 0.00024 20.6 0.3 0.00055 19.5 0.2 1.6 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 KFH43704.1 - 0.0037 16.7 0.0 0.11 12.0 0.0 2.3 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 PrgH PF09480.5 KFH43705.1 - 0.11 11.3 0.0 0.14 11.0 0.0 1.0 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) WD40 PF00400.27 KFH43706.1 - 2.6e-20 71.4 4.6 2.7e-05 23.8 0.1 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat FG-GAP PF01839.18 KFH43706.1 - 1.2 8.9 0.0 1.2 8.9 0.0 2.6 2 1 0 2 2 2 0 FG-GAP repeat EF-hand_7 PF13499.1 KFH43707.1 - 3.9e-14 52.5 0.2 1.1e-09 38.2 0.1 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KFH43707.1 - 3.5e-11 42.0 0.6 0.00089 18.9 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_9 PF14658.1 KFH43707.1 - 7.2e-11 41.8 0.0 2.8e-05 23.9 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 KFH43707.1 - 3.5e-09 35.2 0.8 0.012 14.9 0.0 3.8 4 1 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 KFH43707.1 - 1.6e-06 27.6 1.2 0.00085 18.8 0.1 3.5 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 KFH43707.1 - 0.27 10.6 2.5 2.2 7.7 0.7 2.7 2 0 0 2 2 2 0 EF hand Cpn10 PF00166.16 KFH43708.1 - 3.4e-28 97.4 0.0 3.7e-28 97.2 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit CoA_binding_2 PF13380.1 KFH43709.1 - 3.7e-27 94.7 0.1 4.7e-27 94.4 0.1 1.1 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.14 KFH43709.1 - 0.041 14.3 0.0 0.063 13.7 0.0 1.3 1 0 0 1 1 1 0 CoA binding domain MT-A70 PF05063.9 KFH43710.1 - 3.4e-34 117.9 0.0 4.5e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 MT-A70 Methyltransf_26 PF13659.1 KFH43710.1 - 0.00011 22.1 0.1 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Zn_clus PF00172.13 KFH43712.1 - 1.5e-06 27.9 8.4 2.7e-06 27.1 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFH43712.1 - 0.0025 16.7 0.1 0.0048 15.8 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Med3 PF11593.3 KFH43712.1 - 0.29 10.3 2.2 0.45 9.7 1.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pkinase PF00069.20 KFH43713.1 - 2.9e-59 200.3 0.0 5.5e-59 199.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH43713.1 - 1.3e-22 80.0 0.0 2.5e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFH43713.1 - 0.005 16.5 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KFH43713.1 - 0.15 11.0 0.0 0.27 10.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like CDC73 PF05179.9 KFH43714.1 - 2.5e-46 158.2 0.0 5.2e-46 157.1 0.0 1.5 1 1 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family DUF3678 PF12435.3 KFH43714.1 - 0.085 12.4 0.2 0.085 12.4 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3678) Pfg27 PF09216.5 KFH43715.1 - 0.0062 16.1 0.1 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Pfg27 KH_1 PF00013.24 KFH43715.1 - 0.03 13.9 0.0 0.083 12.5 0.0 1.7 2 0 0 2 2 2 0 KH domain KH_3 PF13014.1 KFH43715.1 - 0.053 13.1 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 KH domain RGS PF00615.14 KFH43716.1 - 6.5e-38 129.4 0.4 1.9e-37 127.9 0.1 2.0 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.16 KFH43716.1 - 3.5e-22 77.9 0.0 2.5e-18 65.5 0.0 3.1 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) TIP_N PF12457.3 KFH43717.1 - 0.11 12.6 0.4 0.17 11.9 0.3 1.2 1 0 0 1 1 1 0 Tuftelin interacting protein N terminal Glycos_transf_2 PF00535.21 KFH43718.1 - 2.8e-24 85.6 0.0 1e-23 83.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KFH43718.1 - 3.3e-10 40.1 0.5 1.3e-06 28.3 0.1 3.1 3 0 0 3 3 3 2 Glycosyltransferase like family 2 YqeY PF09424.5 KFH43719.1 - 8.3e-15 54.8 7.5 1e-14 54.6 5.2 1.1 1 0 0 1 1 1 1 Yqey-like protein PACT_coil_coil PF10495.4 KFH43719.1 - 0.071 13.0 0.4 0.14 12.1 0.2 1.5 1 0 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein Trypsin PF00089.21 KFH43720.1 - 1.1e-12 48.0 0.0 1.7e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 KFH43720.1 - 1.6e-05 24.8 0.0 3.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Methyltransf_23 PF13489.1 KFH43721.1 - 6.2e-17 61.7 0.0 9.2e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH43721.1 - 3.9e-12 46.5 0.0 9.2e-12 45.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH43721.1 - 5.7e-12 45.9 0.0 1e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH43721.1 - 5e-11 42.4 0.0 1e-10 41.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH43721.1 - 5.1e-09 36.7 0.0 1.1e-08 35.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFH43721.1 - 1e-07 32.2 0.0 2.1e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFH43721.1 - 3.5e-07 29.5 0.0 1.2e-05 24.4 0.0 2.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 KFH43721.1 - 1.7e-05 23.9 0.0 3.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 KFH43721.1 - 2.6e-05 24.2 0.0 0.00013 22.0 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 KFH43721.1 - 0.0019 17.3 0.0 0.0062 15.6 0.0 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 KFH43721.1 - 0.0043 16.4 0.0 0.0076 15.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 KFH43721.1 - 0.011 15.6 0.0 0.045 13.7 0.0 1.9 2 0 0 2 2 2 0 FtsJ-like methyltransferase FmrO PF07091.6 KFH43721.1 - 0.02 13.9 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_8 PF05148.10 KFH43721.1 - 0.051 13.1 0.0 0.84 9.2 0.0 2.2 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_PK PF05891.7 KFH43721.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Peptidase_M3 PF01432.15 KFH43722.1 - 4.6e-145 484.1 0.0 5.8e-145 483.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.1 KFH43722.1 - 0.011 15.8 0.1 0.071 13.1 0.0 2.1 2 0 0 2 2 2 0 Effector protein SMK-1 PF04802.10 KFH43724.1 - 2.5e-78 262.0 2.2 2.5e-78 262.0 1.5 2.2 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 RNase_H2-Ydr279 PF09468.5 KFH43724.1 - 0.56 9.3 5.5 1.5 7.9 2.3 2.4 2 1 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) Ras PF00071.17 KFH43725.1 - 8.3e-65 217.0 0.0 1e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFH43725.1 - 1.2e-19 70.9 0.0 2.1e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFH43725.1 - 4.8e-13 48.7 0.0 5.3e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFH43725.1 - 2.8e-06 26.8 0.0 5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFH43725.1 - 6.7e-06 25.4 0.0 8.8e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFH43725.1 - 0.0046 16.8 0.0 0.0064 16.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KFH43725.1 - 0.024 13.8 0.0 0.029 13.5 0.0 1.2 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA PF00004.24 KFH43725.1 - 0.025 14.7 0.0 4.8 7.3 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 KFH43725.1 - 0.053 12.7 0.0 0.14 11.3 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 FeoB_N PF02421.13 KFH43725.1 - 0.062 12.5 0.0 0.3 10.3 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B G-alpha PF00503.15 KFH43725.1 - 0.064 11.9 0.4 11 4.6 0.1 2.7 1 1 1 2 2 2 0 G-protein alpha subunit AAA_29 PF13555.1 KFH43725.1 - 0.091 12.2 0.0 0.28 10.7 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KFH43725.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain SE PF08491.5 KFH43726.1 - 1.9e-85 286.0 0.0 2.6e-85 285.6 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 KFH43726.1 - 1.8e-09 37.1 0.7 1.3e-08 34.2 0.5 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFH43726.1 - 2.3e-09 36.6 0.5 2.3e-07 30.0 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 KFH43726.1 - 0.00014 20.8 0.4 0.0049 15.7 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 KFH43726.1 - 0.00025 20.2 0.0 0.00045 19.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 KFH43726.1 - 0.00028 20.8 0.1 0.00086 19.2 0.1 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFH43726.1 - 0.0006 19.7 0.0 0.0028 17.5 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFH43726.1 - 0.0007 18.5 0.8 0.0024 16.7 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain ApbA PF02558.11 KFH43726.1 - 0.0028 17.1 0.1 0.0046 16.4 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 KFH43726.1 - 0.0044 17.3 0.5 0.041 14.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFH43726.1 - 0.0068 15.3 0.0 0.16 10.8 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein 3HCDH_N PF02737.13 KFH43726.1 - 0.0078 15.8 0.1 0.018 14.6 0.1 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 KFH43726.1 - 0.0092 15.1 1.8 0.018 14.1 1.2 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 KFH43726.1 - 0.016 15.2 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Reticulon PF02453.12 KFH43726.1 - 0.025 14.1 0.0 0.067 12.7 0.0 1.7 1 0 0 1 1 1 0 Reticulon NAD_Gly3P_dh_N PF01210.18 KFH43726.1 - 0.037 13.7 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GDI PF00996.13 KFH43726.1 - 0.11 10.8 0.0 0.16 10.2 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor ThiF PF00899.16 KFH43726.1 - 0.19 11.5 1.0 0.51 10.1 0.2 2.1 3 0 0 3 3 2 0 ThiF family Bystin PF05291.6 KFH43727.1 - 8.6e-127 422.2 0.0 1.2e-126 421.7 0.0 1.1 1 0 0 1 1 1 1 Bystin DUF397 PF04149.7 KFH43728.1 - 0.11 12.1 1.0 0.25 10.9 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF397) 7tm_2 PF00002.19 KFH43729.1 - 1.1e-05 24.6 8.3 1.1e-05 24.6 5.8 1.9 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.16 KFH43729.1 - 1.7e-05 24.0 0.4 4.6e-05 22.6 0.3 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.6 KFH43729.1 - 0.00017 20.5 9.3 0.00017 20.5 6.5 1.7 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.3 KFH43729.1 - 0.0025 17.4 9.9 0.0045 16.5 6.8 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 DUF1705 PF08019.7 KFH43729.1 - 0.065 12.7 0.4 0.065 12.7 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1705) EIF_2_alpha PF07541.7 KFH43730.1 - 1.4e-39 134.3 0.0 2.9e-39 133.3 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 KFH43730.1 - 4.4e-13 49.1 0.7 9.6e-13 48.0 0.5 1.6 1 0 0 1 1 1 1 S1 RNA binding domain YqzE PF14038.1 KFH43731.1 - 0.85 9.4 2.6 1.2 8.9 1.8 1.2 1 0 0 1 1 1 0 YqzE-like protein Kelch_5 PF13854.1 KFH43733.1 - 9.9e-13 47.7 4.0 5.7e-12 45.3 1.4 3.2 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 KFH43733.1 - 0.00014 21.9 5.3 0.00033 20.7 0.3 4.0 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_6 PF13964.1 KFH43733.1 - 0.0049 16.9 4.0 0.079 13.1 0.3 4.0 4 1 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 KFH43733.1 - 0.1 12.1 2.6 3.3 7.3 0.0 2.8 2 0 0 2 2 2 0 Kelch motif Kelch_4 PF13418.1 KFH43733.1 - 0.59 9.9 7.9 0.66 9.7 0.3 4.6 6 1 0 6 6 6 0 Galactose oxidase, central domain SKG6 PF08693.5 KFH43733.1 - 5.4 6.4 11.4 0.056 12.7 2.2 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Ribosomal_L23 PF00276.15 KFH43734.1 - 9.8e-14 51.0 0.0 1.6e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L23 MRP-S26 PF14943.1 KFH43734.1 - 0.0026 17.3 3.9 0.0039 16.7 2.4 1.5 1 1 0 1 1 1 1 Mitochondrial ribosome subunit S26 Toxin_8 PF07365.7 KFH43735.1 - 0.016 15.1 0.4 0.022 14.7 0.3 1.3 1 0 0 1 1 1 0 Alpha conotoxin precursor Glyco_hydro_61 PF03443.9 KFH43736.1 - 6.5e-43 147.0 0.0 9.5e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 BIR PF00653.16 KFH43737.1 - 1.1e-40 137.9 5.2 3.9e-20 72.0 0.2 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Mito_carr PF00153.22 KFH43738.1 - 3.8e-61 202.8 0.8 1.6e-19 69.3 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.22 KFH43739.1 - 8.5e-61 201.7 1.9 2.9e-21 74.9 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Ectatomin PF06457.6 KFH43739.1 - 0.035 13.8 0.0 0.069 12.8 0.0 1.5 1 0 0 1 1 1 0 Ectatomin Ribosomal_L11_N PF03946.9 KFH43740.1 - 2.3e-26 91.0 0.1 1.1e-25 88.8 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 KFH43740.1 - 1.1e-22 79.9 0.3 1.8e-22 79.2 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain DUF1917 PF08939.5 KFH43742.1 - 3.2e-64 217.0 1.9 8e-64 215.6 1.3 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1917) DUF2828 PF11443.3 KFH43742.1 - 0.023 12.8 0.2 0.027 12.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) CDP-OH_P_transf PF01066.16 KFH43743.1 - 4e-15 55.9 3.8 6.8e-15 55.2 2.6 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase PH PF00169.24 KFH43744.1 - 6.6e-12 45.5 0.0 1.5e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 PH domain Prominin PF05478.6 KFH43744.1 - 0.0023 15.5 0.5 0.0035 14.9 0.4 1.2 1 0 0 1 1 1 1 Prominin p450 PF00067.17 KFH43745.1 - 5.9e-11 41.5 0.0 7.4e-11 41.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Chordopox_A13L PF05961.6 KFH43746.1 - 0.015 15.2 1.4 0.034 14.0 0.3 1.9 2 0 0 2 2 2 0 Chordopoxvirus A13L protein DUF1183 PF06682.7 KFH43746.1 - 0.035 13.6 0.0 0.035 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Methyltransf_23 PF13489.1 KFH43747.1 - 1e-23 83.8 0.0 1.4e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH43747.1 - 3.2e-11 43.5 0.0 6.5e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH43747.1 - 5.3e-09 36.6 0.0 7.9e-08 32.8 0.0 2.5 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH43747.1 - 2.9e-08 34.0 0.0 2.5e-07 31.0 0.0 2.5 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH43747.1 - 7e-07 28.9 0.0 8.6e-06 25.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFH43747.1 - 5.2e-06 26.7 0.0 1.3e-05 25.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFH43747.1 - 0.00069 18.7 0.0 0.018 14.1 0.0 2.3 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 KFH43747.1 - 0.00092 18.4 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 KFH43747.1 - 0.006 16.6 0.0 0.025 14.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KFH43747.1 - 0.0064 15.5 0.0 0.014 14.4 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_16 PF10294.4 KFH43747.1 - 0.014 14.8 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase DUF938 PF06080.7 KFH43747.1 - 0.026 14.0 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FtsJ PF01728.14 KFH43747.1 - 0.035 14.0 0.0 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 FtsJ-like methyltransferase MTS PF05175.9 KFH43747.1 - 0.08 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Pkinase PF00069.20 KFH43748.1 - 3.2e-74 249.3 0.0 4.4e-74 248.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH43748.1 - 1.5e-31 109.4 0.0 2e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH43748.1 - 0.00062 18.8 0.0 0.0012 17.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFH43748.1 - 0.0017 17.4 0.1 0.0029 16.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFH43748.1 - 0.0089 15.7 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KFH43748.1 - 0.062 12.1 0.0 0.096 11.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Gag_p6 PF08705.6 KFH43748.1 - 0.085 12.8 0.1 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Gag protein p6 S_100 PF01023.14 KFH43748.1 - 0.12 11.7 0.3 0.4 10.0 0.2 1.9 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain RPAP1_C PF08620.5 KFH43750.1 - 8.1e-30 102.4 0.0 1.4e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 KFH43750.1 - 2.5e-13 49.3 3.3 5.2e-13 48.3 2.3 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal GIDA_assoc_3 PF13932.1 KFH43750.1 - 0.00031 20.7 0.0 0.00062 19.7 0.0 1.5 1 0 0 1 1 1 1 GidA associated domain 3 LCAT PF02450.10 KFH43751.1 - 6.4e-98 328.2 0.1 8.5e-98 327.8 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Whi5 PF08528.6 KFH43752.1 - 2e-11 43.2 0.1 3.3e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Whi5 like DUF601 PF04642.7 KFH43752.1 - 0.16 11.3 1.8 0.24 10.7 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF601 GTP_EFTU PF00009.22 KFH43754.1 - 1.7e-38 131.9 3.2 7.9e-38 129.7 2.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KFH43754.1 - 1.2e-23 83.0 1.9 3e-23 81.7 1.3 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KFH43754.1 - 1.1e-11 44.6 1.9 4.4e-07 29.9 0.0 2.8 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KFH43754.1 - 8.6e-08 32.1 0.1 2.3e-07 30.7 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFH43754.1 - 2e-06 28.2 0.2 7.7e-06 26.3 0.1 2.0 2 0 0 2 2 1 1 Miro-like protein SRPRB PF09439.5 KFH43754.1 - 4.2e-05 22.8 0.2 0.00016 20.9 0.1 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 KFH43754.1 - 5.7e-05 22.4 0.1 0.0001 21.5 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.13 KFH43754.1 - 0.00014 21.1 0.3 0.0004 19.7 0.2 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.4 KFH43754.1 - 0.00047 19.6 0.2 0.0012 18.3 0.1 1.7 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation IF2_N PF04760.10 KFH43754.1 - 0.00054 19.5 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Ras PF00071.17 KFH43754.1 - 0.01 15.2 0.1 0.02 14.2 0.1 1.5 1 0 0 1 1 1 0 Ras family ATP_bind_1 PF03029.12 KFH43754.1 - 0.01 15.4 0.0 0.029 13.9 0.0 1.7 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.18 KFH43754.1 - 0.045 13.5 0.1 7.9 6.2 0.3 2.8 1 1 1 2 2 2 0 Dynamin family Fungal_trans_2 PF11951.3 KFH43755.1 - 1.5e-11 43.5 0.1 5.2e-11 41.7 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH43755.1 - 1e-06 28.5 13.1 2e-06 27.5 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transglut_core2 PF13369.1 KFH43756.1 - 2e-18 66.3 0.0 3.9e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily YccV-like PF08755.6 KFH43756.1 - 2.2e-06 27.5 0.0 1.3e-05 25.0 0.0 2.3 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like F-box-like PF12937.2 KFH43756.1 - 2.5e-05 23.9 0.6 8.6e-05 22.1 0.4 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFH43756.1 - 0.00089 18.8 0.1 0.0021 17.6 0.1 1.7 1 0 0 1 1 1 1 F-box domain VHS PF00790.14 KFH43757.1 - 1.8e-45 154.0 0.0 4.6e-45 152.7 0.0 1.7 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 KFH43757.1 - 1.1e-24 86.3 0.1 2.6e-24 85.1 0.1 1.6 1 0 0 1 1 1 1 GAT domain Alpha_adaptinC2 PF02883.15 KFH43757.1 - 2e-18 66.7 0.0 6.9e-18 65.0 0.0 1.9 2 0 0 2 2 2 1 Adaptin C-terminal domain DUF1918 PF08940.6 KFH43758.1 - 0.0018 17.5 3.1 6 6.2 0.0 5.1 4 0 0 4 4 4 2 Domain of unknown function (DUF1918) I-set PF07679.11 KFH43758.1 - 0.0097 15.7 0.5 0.75 9.6 0.2 3.4 3 0 0 3 3 3 1 Immunoglobulin I-set domain SURF6 PF04935.7 KFH43759.1 - 5e-49 166.4 31.3 5e-49 166.4 21.7 4.8 2 1 2 4 4 4 1 Surfeit locus protein 6 RRP14 PF15459.1 KFH43759.1 - 1.5e-19 69.7 0.4 1.5e-19 69.7 0.3 7.1 7 1 0 7 7 7 1 60S ribosome biogenesis protein Rrp14 CoA_trans PF01144.18 KFH43760.1 - 1.7e-98 328.0 0.5 3.3e-59 199.7 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 KFH43760.1 - 0.0041 16.7 0.0 0.008 15.8 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain SET PF00856.23 KFH43761.1 - 2.8e-15 57.0 0.0 5.2e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 SET domain Pribosyl_synth PF14572.1 KFH43761.1 - 0.037 13.7 0.0 0.055 13.2 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain SAF PF08666.7 KFH43761.1 - 0.066 13.6 0.2 2.4 8.6 0.0 2.6 3 0 0 3 3 3 0 SAF domain PP28 PF10252.4 KFH43763.1 - 8e-27 93.0 15.1 8e-27 93.0 10.5 3.3 2 2 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 CENP-B_dimeris PF09026.5 KFH43763.1 - 3.1 8.0 36.1 0.39 10.9 12.0 3.0 3 0 0 3 3 3 0 Centromere protein B dimerisation domain DUF2013 PF09431.5 KFH43764.1 - 2.1e-51 173.3 1.2 2.1e-51 173.3 0.8 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) DUF2170 PF09938.4 KFH43764.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2170) Acetyltransf_1 PF00583.19 KFH43765.1 - 2.9e-18 65.6 0.0 4.3e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFH43765.1 - 3.9e-10 39.7 0.0 5.5e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFH43765.1 - 2.7e-09 36.6 0.0 3.6e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KFH43765.1 - 4.8e-09 36.3 0.0 7.2e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KFH43765.1 - 1.3e-07 31.8 0.0 1.8e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KFH43765.1 - 4.9e-07 29.7 0.0 6e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFH43765.1 - 9.5e-07 28.7 0.0 1.6e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KFH43765.1 - 0.009 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KFH43765.1 - 0.016 15.0 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Sec23_trunk PF04811.10 KFH43766.1 - 8.6e-70 234.8 0.0 1.3e-69 234.2 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KFH43766.1 - 7.7e-23 79.8 0.0 1.8e-21 75.4 0.0 2.4 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 KFH43766.1 - 5e-18 64.3 5.4 8.6e-18 63.6 3.7 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 KFH43766.1 - 1.1e-17 64.2 0.0 2.3e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 KFH43766.1 - 3.1e-09 36.4 0.0 7.3e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Metallopep PF12044.3 KFH43767.1 - 2.3e-164 546.8 0.0 3.2e-164 546.4 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 KFH43767.1 - 0.00018 21.4 0.0 0.00076 19.3 0.0 2.1 1 1 0 1 1 1 1 Jacalin-like lectin domain Reprolysin_4 PF13583.1 KFH43767.1 - 0.091 12.2 0.9 0.18 11.3 0.6 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFH43767.1 - 0.11 12.5 0.7 0.19 11.7 0.5 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Gar1 PF04410.9 KFH43768.1 - 1.4e-44 151.2 0.1 1.4e-44 151.2 0.0 1.8 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region 2-oxoacid_dh PF00198.18 KFH43769.1 - 4.3e-80 268.3 0.3 5.8e-80 267.8 0.2 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KFH43769.1 - 8.7e-16 57.3 2.0 1.8e-15 56.2 1.4 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 KFH43769.1 - 0.043 13.4 0.3 0.23 11.1 0.1 2.1 1 1 1 2 2 2 0 Biotin-lipoyl like YL1 PF05764.8 KFH43769.1 - 0.16 11.5 11.1 0.21 11.1 7.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Trypan_PARP PF05887.6 KFH43769.1 - 0.23 11.2 23.1 0.39 10.5 16.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Neisseria_TspB PF05616.8 KFH43769.1 - 0.28 9.4 7.8 0.45 8.8 5.4 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DUF3614 PF12267.3 KFH43769.1 - 0.33 11.2 0.0 0.33 11.2 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3614) DUF1180 PF06679.7 KFH43769.1 - 4.6 7.1 8.1 8 6.3 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) p450 PF00067.17 KFH43770.1 - 2.4e-48 164.8 0.0 2.8e-48 164.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SWM_repeat PF13753.1 KFH43770.1 - 0.016 14.2 0.0 0.021 13.8 0.0 1.1 1 0 0 1 1 1 0 Putative flagellar system-associated repeat eIF2A PF08662.6 KFH43771.1 - 2.1e-77 259.2 0.0 4.2e-76 254.9 0.0 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 KFH43771.1 - 9.4e-08 31.6 0.4 0.28 11.1 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat CDV3 PF15359.1 KFH43771.1 - 0.039 14.0 0.3 0.039 14.0 0.2 3.1 4 0 0 4 4 4 0 Carnitine deficiency-associated protein 3 TLD PF07534.11 KFH43772.1 - 3.8e-27 94.9 0.0 9.1e-15 54.8 0.0 2.3 2 0 0 2 2 2 2 TLD CP2 PF04516.10 KFH43773.1 - 1e-82 276.7 0.0 1.6e-82 276.1 0.0 1.3 1 0 0 1 1 1 1 CP2 transcription factor Phage_G PF02306.10 KFH43773.1 - 0.089 12.4 0.1 0.089 12.4 0.0 2.0 2 0 0 2 2 2 0 Major spike protein (G protein) Syndecan PF01034.15 KFH43774.1 - 0.0011 18.6 0.1 0.002 17.7 0.1 1.3 1 0 0 1 1 1 1 Syndecan domain Herpes_gE PF02480.11 KFH43774.1 - 0.16 10.1 0.0 0.31 9.2 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E FTR1 PF03239.9 KFH43774.1 - 0.27 10.1 0.2 0.41 9.5 0.1 1.1 1 0 0 1 1 1 0 Iron permease FTR1 family DUF367 PF04034.8 KFH43775.1 - 4.6e-47 158.7 0.0 6.2e-47 158.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 KFH43775.1 - 1.6e-12 46.7 0.6 3e-12 45.9 0.4 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Daxx PF03344.10 KFH43775.1 - 0.001 17.6 22.2 0.0014 17.1 15.4 1.1 1 0 0 1 1 1 1 Daxx Family Microtub_assoc PF07989.6 KFH43776.1 - 4.8e-28 96.7 3.8 4.8e-28 96.7 2.6 10.5 9 4 3 13 13 13 1 Microtubule associated IncA PF04156.9 KFH43776.1 - 6.9e-13 48.6 158.4 5.9e-05 22.7 16.4 8.6 1 1 7 8 8 8 6 IncA protein AAA_13 PF13166.1 KFH43776.1 - 1.4e-10 40.3 91.9 3e-06 26.0 16.2 4.6 1 1 3 4 4 4 4 AAA domain PACT_coil_coil PF10495.4 KFH43776.1 - 1.6e-09 37.5 0.7 4.3e-09 36.1 0.5 1.8 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Reo_sigmaC PF04582.7 KFH43776.1 - 6.6e-08 32.0 44.3 0.11 11.6 0.3 7.4 1 1 7 8 8 8 6 Reovirus sigma C capsid protein Spc7 PF08317.6 KFH43776.1 - 6.7e-08 31.5 124.2 0.0006 18.5 14.6 7.7 1 1 8 9 9 9 7 Spc7 kinetochore protein WEMBL PF05701.6 KFH43776.1 - 3.8e-05 22.3 18.9 3.8e-05 22.3 13.1 4.7 1 1 4 5 5 4 2 Weak chloroplast movement under blue light TMF_DNA_bd PF12329.3 KFH43776.1 - 0.0012 18.6 12.7 0.0012 18.6 8.8 12.9 6 3 6 12 12 12 6 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.4 KFH43776.1 - 0.0039 17.0 19.4 0.0039 17.0 13.4 9.4 2 1 8 10 10 10 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 KFH43776.1 - 0.0051 16.5 12.9 0.0051 16.5 9.0 10.4 1 1 8 10 10 10 1 TPR/MLP1/MLP2-like protein MscS_porin PF12795.2 KFH43776.1 - 0.03 13.6 133.4 0.022 14.0 9.5 8.1 2 1 6 8 8 8 0 Mechanosensitive ion channel porin domain ATG_C PF09333.6 KFH43776.1 - 0.036 14.2 2.1 0.2 11.8 0.1 3.5 2 0 0 2 2 2 0 ATG C terminal domain ATG16 PF08614.6 KFH43776.1 - 1.1 9.0 157.4 0.094 12.5 8.9 9.8 1 1 9 10 10 10 0 Autophagy protein 16 (ATG16) GAS PF13851.1 KFH43776.1 - 2.8 7.0 132.2 0.09 11.9 19.0 9.0 1 1 8 9 9 9 0 Growth-arrest specific micro-tubule binding HUN PF08729.5 KFH43777.1 - 2.2e-12 46.6 0.2 5.4e-12 45.4 0.1 1.7 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Peptidase_C12 PF01088.16 KFH43778.1 - 1.6e-53 181.0 0.1 9.7e-53 178.5 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Topoisom_I_N PF02919.10 KFH43778.1 - 0.087 12.1 0.1 0.18 11.0 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment GPP34 PF05719.6 KFH43779.1 - 4.2e-66 222.9 0.5 5.6e-66 222.5 0.3 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Nrap PF03813.9 KFH43780.1 - 3.1e-299 994.8 0.0 4.3e-299 994.3 0.0 1.2 1 0 0 1 1 1 1 Nrap protein WD40 PF00400.27 KFH43782.1 - 1.7e-07 30.8 3.2 0.46 10.4 0.0 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat Methyltransf_PK PF05891.7 KFH43784.1 - 4.1e-72 242.0 0.0 4.8e-72 241.8 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.2 KFH43784.1 - 8.7e-05 23.0 0.0 0.00035 21.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH43784.1 - 0.00011 21.9 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KFH43784.1 - 0.012 14.8 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Acetyltransf_1 PF00583.19 KFH43785.1 - 2.2e-10 40.4 0.0 3e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFH43785.1 - 1.6e-09 37.7 0.0 2.2e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Aldo_ket_red PF00248.16 KFH43786.1 - 1.9e-48 164.7 0.0 2.2e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family NmrA PF05368.8 KFH43786.1 - 0.12 11.5 0.0 0.25 10.5 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family Beta-lactamase PF00144.19 KFH43787.1 - 4e-46 157.5 0.0 7.4e-46 156.6 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase Glyco_tranf_2_4 PF13704.1 KFH43787.1 - 0.081 13.2 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 Phosphoesterase PF04185.9 KFH43789.1 - 0.0001 21.6 0.0 0.00011 21.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoesterase family GMC_oxred_N PF00732.14 KFH43790.1 - 4e-55 187.0 0.0 5.3e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFH43790.1 - 4.9e-30 104.7 0.0 8.4e-30 103.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KFH43790.1 - 2.3e-05 23.4 0.5 0.073 11.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KFH43790.1 - 5.6e-05 22.2 0.2 9.2e-05 21.5 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KFH43790.1 - 0.00022 20.2 0.1 0.055 12.3 0.1 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KFH43790.1 - 0.035 13.1 0.5 4 6.3 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.9 KFH43790.1 - 0.038 12.6 0.1 0.055 12.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_8 PF13450.1 KFH43790.1 - 0.05 13.6 0.1 0.14 12.1 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFH43790.1 - 0.056 13.3 0.0 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFH43790.1 - 0.13 11.3 0.1 0.27 10.2 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Lipase_3 PF01764.20 KFH43791.1 - 7.7e-16 57.9 0.0 3e-15 56.0 0.0 1.9 1 1 0 1 1 1 1 Lipase (class 3) adh_short PF00106.20 KFH43792.1 - 3.5e-30 105.1 0.2 6.2e-30 104.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH43792.1 - 2.1e-21 76.7 0.0 2.9e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH43792.1 - 7.7e-13 48.4 0.2 1.3e-12 47.7 0.1 1.5 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KFH43792.1 - 0.00091 18.9 0.7 0.0017 18.1 0.5 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KFH43792.1 - 0.016 14.6 0.0 0.023 14.1 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 KFH43792.1 - 0.11 12.9 1.0 1.5 9.3 0.2 2.5 2 1 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent ADH_zinc_N PF00107.21 KFH43792.1 - 0.11 12.0 0.2 0.23 11.0 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 KFH43792.1 - 0.37 10.7 3.0 0.42 10.5 0.5 2.2 2 1 0 2 2 2 0 NADH(P)-binding Response_reg PF00072.19 KFH43793.1 - 1.6e-21 76.4 0.0 1.8e-14 53.6 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain DUF2052 PF09747.4 KFH43794.1 - 8.9e-28 97.4 0.1 1.2e-27 97.0 0.0 1.2 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Mito_carr PF00153.22 KFH43795.1 - 2.4e-75 248.3 2.2 1.3e-24 85.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Dioxygenase_N PF04444.9 KFH43795.1 - 0.098 12.6 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Catechol dioxygenase N terminus CRF PF00473.12 KFH43795.1 - 0.1 12.7 0.3 0.64 10.1 0.1 2.3 2 0 0 2 2 2 0 Corticotropin-releasing factor family 3-dmu-9_3-mt PF06983.8 KFH43796.1 - 1.8e-45 154.0 0.4 2.6e-45 153.5 0.2 1.3 2 0 0 2 2 2 1 3-demethylubiquinone-9 3-methyltransferase AvrRpt-cleavage PF05627.6 KFH43796.1 - 0.017 14.1 0.7 0.03 13.3 0.1 1.7 2 0 0 2 2 2 0 Cleavage site for pathogenic type III effector avirulence factor Avr PRP21_like_P PF12230.3 KFH43797.1 - 6.7e-60 202.4 19.0 9.9e-60 201.8 12.1 2.0 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 KFH43797.1 - 1.8e-40 136.3 0.7 2e-19 68.9 0.0 2.4 2 0 0 2 2 2 2 Surp module DUF2956 PF11169.3 KFH43797.1 - 3.6 7.5 10.0 0.11 12.4 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) DUF2439 PF10382.4 KFH43799.1 - 9.3e-22 77.0 0.0 1.9e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) dCMP_cyt_deam_1 PF00383.17 KFH43800.1 - 3.2e-20 71.6 0.0 1.1e-19 69.9 0.0 1.9 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 KFH43800.1 - 0.0049 16.7 0.1 0.056 13.2 0.0 2.7 3 0 0 3 3 3 1 Bd3614-like deaminase PMT PF02366.13 KFH43802.1 - 2.2e-78 263.0 17.0 4.6e-78 261.9 11.8 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KFH43802.1 - 5.6e-54 182.5 0.0 9.8e-54 181.7 0.0 1.4 1 0 0 1 1 1 1 MIR domain Phosphoesterase PF04185.9 KFH43804.1 - 1.9e-08 33.9 0.1 1.6e-07 30.9 0.1 1.9 1 1 0 1 1 1 1 Phosphoesterase family Glyco_hydro_61 PF03443.9 KFH43806.1 - 1.4e-79 266.9 0.0 1.6e-79 266.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ADH_N PF08240.7 KFH43807.1 - 7.5e-28 96.4 1.5 1.7e-27 95.3 0.1 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFH43807.1 - 2.2e-17 62.7 1.2 3.8e-17 62.0 0.9 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_2 PF00890.19 KFH43807.1 - 0.0027 16.6 4.6 0.0037 16.1 3.2 1.2 1 0 0 1 1 1 1 FAD binding domain UDPG_MGDP_dh_N PF03721.9 KFH43807.1 - 0.0079 15.5 1.3 0.017 14.5 0.5 1.9 1 1 1 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.16 KFH43807.1 - 0.018 14.6 0.5 0.039 13.5 0.3 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 KFH43807.1 - 0.02 15.0 0.4 0.051 13.6 0.3 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 KFH43807.1 - 0.031 14.5 0.3 0.067 13.4 0.2 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 KFH43807.1 - 0.049 12.7 0.0 0.089 11.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 KFH43807.1 - 0.082 12.9 0.3 0.13 12.3 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFH43807.1 - 0.084 11.9 0.2 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KFH43807.1 - 0.091 11.2 1.2 0.13 10.6 0.9 1.2 1 0 0 1 1 1 0 HI0933-like protein YdfZ PF14001.1 KFH43807.1 - 0.091 13.0 0.1 0.32 11.2 0.0 1.9 2 0 0 2 2 2 0 YdfZ protein 3HCDH_N PF02737.13 KFH43807.1 - 0.21 11.2 1.9 0.34 10.5 1.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SET PF00856.23 KFH43808.1 - 5.1e-18 65.8 0.0 1.5e-17 64.4 0.0 1.7 2 0 0 2 2 2 1 SET domain SNARE PF05739.14 KFH43810.1 - 6.6e-18 64.1 0.4 6.6e-18 64.1 0.3 3.1 4 0 0 4 4 4 1 SNARE domain Syntaxin PF00804.20 KFH43810.1 - 4.4e-16 58.9 0.5 4.4e-16 58.9 0.4 3.4 3 1 0 3 3 3 1 Syntaxin MCPsignal PF00015.16 KFH43810.1 - 0.0043 16.6 0.7 0.0043 16.6 0.5 2.7 3 0 0 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain zf-C4H2 PF10146.4 KFH43810.1 - 0.012 15.6 2.6 0.79 9.7 0.1 2.3 1 1 1 2 2 2 0 Zinc finger-containing protein Sed5p PF11416.3 KFH43810.1 - 0.016 14.6 0.0 0.045 13.1 0.0 1.7 1 0 0 1 1 1 0 Integral membrane protein Sed5p Syntaxin-18_N PF10496.4 KFH43810.1 - 0.03 14.1 1.8 0.28 11.0 0.2 2.6 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus SF-assemblin PF06705.6 KFH43810.1 - 0.099 11.7 6.0 0.34 10.0 1.2 2.4 2 0 0 2 2 2 0 SF-assemblin/beta giardin Spc7 PF08317.6 KFH43810.1 - 0.16 10.5 6.4 0.091 11.4 1.3 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein NPV_P10 PF05531.7 KFH43810.1 - 0.26 11.5 4.8 40 4.5 1.3 3.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.4 KFH43810.1 - 0.49 9.2 12.0 0.52 9.2 0.2 3.0 2 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Syntaxin-6_N PF09177.6 KFH43810.1 - 1.6 9.2 11.1 1.8 9.0 0.1 3.9 4 0 0 4 4 4 0 Syntaxin 6, N-terminal Prominin PF05478.6 KFH43810.1 - 2.5 5.5 7.4 16 2.8 4.3 1.9 1 1 1 2 2 2 0 Prominin ApoLp-III PF07464.6 KFH43810.1 - 8.5 6.3 9.9 3 7.8 1.5 2.7 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) RTA1 PF04479.8 KFH43811.1 - 1.2e-56 191.7 8.5 1.9e-56 191.1 5.9 1.2 1 0 0 1 1 1 1 RTA1 like protein Kei1 PF08552.6 KFH43811.1 - 0.0069 16.0 0.1 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Caveolin PF01146.12 KFH43811.1 - 0.12 11.9 1.1 0.31 10.5 0.7 1.6 1 0 0 1 1 1 0 Caveolin Glyco_hydro_43 PF04616.9 KFH43812.1 - 2.4e-32 112.1 4.8 5e-31 107.8 3.3 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 RC-P840_PscD PF10657.4 KFH43812.1 - 0.14 12.0 0.0 0.39 10.5 0.0 1.6 1 1 1 2 2 2 0 Photosystem P840 reaction centre protein PscD Cu-oxidase_3 PF07732.10 KFH43813.1 - 4e-35 120.0 0.1 4.9e-34 116.5 0.1 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 KFH43813.1 - 4.8e-24 85.0 0.0 9.4e-23 80.8 0.0 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KFH43813.1 - 2.2e-14 53.1 8.8 1.4e-12 47.2 1.4 4.2 3 2 0 3 3 3 2 Multicopper oxidase KorB_C PF06613.6 KFH43813.1 - 0.11 12.0 0.0 0.28 10.6 0.0 1.7 1 0 0 1 1 1 0 KorB C-terminal beta-barrel domain SnoaL_4 PF13577.1 KFH43814.1 - 1.2e-10 41.3 0.3 1.6e-10 40.9 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain PknH_C PF14032.1 KFH43814.1 - 0.15 11.6 0.1 0.23 10.9 0.1 1.2 1 0 0 1 1 1 0 PknH-like extracellular domain Bot1p PF12298.3 KFH43815.1 - 4e-49 166.8 6.6 5.8e-49 166.3 4.6 1.3 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein Fungal_trans_2 PF11951.3 KFH43816.1 - 1.5e-08 33.6 0.1 2.1e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH43816.1 - 0.24 11.3 5.5 0.43 10.5 3.8 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MARVEL PF01284.18 KFH43818.1 - 3.1e-06 27.0 7.8 3.1e-06 27.0 5.4 2.1 1 1 1 2 2 2 2 Membrane-associating domain ABC2_membrane_5 PF13346.1 KFH43818.1 - 0.0016 17.7 0.5 0.002 17.4 0.3 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein FAD_binding_4 PF01565.18 KFH43819.1 - 2.1e-20 72.5 3.6 1.3e-19 70.0 2.5 2.2 1 1 0 1 1 1 1 FAD binding domain PX PF00787.19 KFH43820.1 - 8.7e-24 83.4 0.0 1.1e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 PX domain Zn_clus PF00172.13 KFH43821.1 - 0.2 11.5 12.3 0.42 10.5 8.5 1.6 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Na_H_Exchanger PF00999.16 KFH43823.1 - 7.9e-26 90.4 23.0 1.1e-25 89.9 15.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family EmrE PF13536.1 KFH43823.1 - 7.2 6.8 15.1 4 7.6 4.7 2.7 1 1 2 3 3 3 0 Multidrug resistance efflux transporter Sec2p PF06428.6 KFH43824.1 - 3.3e-23 81.4 11.8 3.3e-23 81.4 8.2 2.3 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p zf-ZPR1 PF03367.8 KFH43824.1 - 0.55 9.3 3.8 0.37 9.9 0.5 2.0 1 1 1 2 2 2 0 ZPR1 zinc-finger domain DUF3584 PF12128.3 KFH43824.1 - 0.97 6.6 22.0 1.4 6.1 15.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HrpA_pilin PF09589.5 KFH43824.1 - 6.1 7.2 10.9 1.9e+02 2.4 7.6 2.7 1 1 0 1 1 1 0 HrpA pilus formation protein KR PF08659.5 KFH43827.1 - 0.05 13.2 0.0 0.076 12.6 0.0 1.2 1 0 0 1 1 1 0 KR domain Pescadillo_N PF06732.6 KFH43829.1 - 1.2e-114 382.3 1.1 1.2e-114 382.3 0.8 1.7 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 KFH43829.1 - 3e-10 40.1 0.0 8.7e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Kelch_4 PF13418.1 KFH43830.1 - 1.8e-43 146.0 22.8 1.2e-10 41.0 0.2 6.7 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 KFH43830.1 - 2.9e-40 135.6 12.5 7e-07 29.0 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 KFH43830.1 - 4.4e-40 134.9 15.1 4.1e-08 32.6 0.2 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 KFH43830.1 - 1.8e-39 132.9 34.1 1.2e-08 34.8 0.3 7.6 9 0 0 9 9 9 5 Galactose oxidase, central domain Kelch_6 PF13964.1 KFH43830.1 - 7.1e-35 117.7 16.2 2e-06 27.7 0.0 6.3 3 2 3 6 6 6 6 Kelch motif Kelch_2 PF07646.10 KFH43830.1 - 3.6e-31 105.7 14.7 3.5e-06 26.5 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Glyco_tranf_2_3 PF13641.1 KFH43831.1 - 4.4e-18 65.9 0.1 6.4e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KFH43831.1 - 1.3e-09 37.5 0.0 4.1e-09 35.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KFH43831.1 - 1.9e-07 30.9 0.0 5.3e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Ribosomal_S17 PF00366.15 KFH43833.1 - 1e-28 99.1 0.7 1.6e-28 98.5 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 DUF676 PF05057.9 KFH43834.1 - 4.1e-06 26.2 0.0 6.3e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KFH43834.1 - 4.2e-06 26.5 0.0 1.2e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KFH43834.1 - 0.011 15.5 0.0 0.023 14.4 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFH43834.1 - 0.017 15.0 0.0 0.045 13.6 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family PDZ_1 PF12812.2 KFH43834.1 - 0.019 14.8 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 PDZ-like domain Abhydrolase_8 PF06259.7 KFH43834.1 - 0.026 14.0 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Spt4 PF06093.8 KFH43834.1 - 0.13 12.1 0.0 0.42 10.5 0.0 1.9 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger GWT1 PF06423.7 KFH43835.1 - 7e-42 142.7 3.8 7e-42 142.7 2.6 2.0 2 0 0 2 2 2 1 GWT1 Prefoldin_3 PF13758.1 KFH43836.1 - 3.7e-31 106.8 1.1 9.3e-31 105.5 0.8 1.7 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.2 KFH43836.1 - 2.4e-12 47.6 0.1 2.4e-12 47.6 0.1 5.4 6 2 0 6 6 6 1 Domain of unknown function (DUF3835) Prefoldin PF02996.12 KFH43836.1 - 0.011 15.3 1.6 0.22 11.1 0.2 2.4 2 0 0 2 2 2 0 Prefoldin subunit Prefoldin_2 PF01920.15 KFH43836.1 - 0.022 14.5 4.4 0.22 11.2 0.1 2.8 3 0 0 3 3 3 0 Prefoldin subunit FlxA PF14282.1 KFH43836.1 - 0.023 14.6 1.4 0.86 9.5 0.1 3.3 3 0 0 3 3 3 0 FlxA-like protein FliJ PF02050.11 KFH43836.1 - 0.049 13.6 3.0 0.23 11.5 0.1 2.5 2 0 0 2 2 2 0 Flagellar FliJ protein MFS_1 PF07690.11 KFH43837.1 - 2.5e-51 174.4 46.8 2.5e-51 174.4 32.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KFH43837.1 - 4.1e-23 81.4 11.8 5.1e-23 81.1 6.8 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KFH43837.1 - 4.5e-17 61.7 3.4 4.5e-17 61.7 2.4 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter DUF3357 PF11837.3 KFH43837.1 - 0.00093 19.0 0.4 0.62 9.9 0.0 3.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3357) Trypan_PARP PF05887.6 KFH43837.1 - 0.04 13.7 5.0 0.096 12.5 3.5 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) YrhC PF14143.1 KFH43837.1 - 2.3 8.2 4.6 45 4.0 0.1 3.6 3 0 0 3 3 3 0 YrhC-like protein Mur_ligase_C PF02875.16 KFH43838.1 - 0.00011 22.1 0.1 0.00059 19.8 0.0 2.2 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Mur_ligase_M PF08245.7 KFH43838.1 - 0.0066 16.5 0.0 5.5 6.9 0.0 2.6 2 1 0 2 2 2 2 Mur ligase middle domain Mut7-C PF01927.11 KFH43838.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Mut7-C RNAse domain Ribosomal_S30 PF04758.9 KFH43839.1 - 0.1 12.3 0.5 0.22 11.2 0.1 1.7 2 0 0 2 2 2 0 Ribosomal protein S30 FH2 PF02181.18 KFH43839.1 - 0.1 11.4 3.4 0.61 8.9 1.1 2.0 1 1 1 2 2 2 0 Formin Homology 2 Domain DUF488 PF04343.8 KFH43839.1 - 0.52 10.6 5.1 0.61 10.4 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF488 TPR_2 PF07719.12 KFH43839.1 - 0.68 9.9 2.6 2 8.5 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFH43839.1 - 2.9 7.9 5.7 2.1 8.3 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ABC_tran_2 PF12848.2 KFH43839.1 - 5.7 6.8 10.4 10 6.0 1.4 2.2 1 1 1 2 2 2 0 ABC transporter Kinesin PF00225.18 KFH43840.1 - 1.4e-109 365.8 0.9 1.4e-109 365.8 0.6 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bind PF13931.1 KFH43840.1 - 1.7e-05 24.9 1.4 1.7e-05 24.9 0.9 5.6 3 2 2 5 5 5 1 Kinesin-associated microtubule-binding LigD_N PF13298.1 KFH43842.1 - 8.8e-27 93.2 0.0 2.1e-26 92.0 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase Ligase (LigD) Pkinase PF00069.20 KFH43844.1 - 3e-59 200.3 0.1 3.4e-59 200.0 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH43844.1 - 3.4e-19 68.9 0.0 4.8e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFH43844.1 - 6.5e-09 35.8 0.0 5.7e-06 26.2 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFH43844.1 - 0.0096 15.5 0.1 0.025 14.1 0.1 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 KFH43844.1 - 0.026 13.5 0.0 0.037 12.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 KFH43844.1 - 0.069 12.2 0.1 0.15 11.1 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Dus PF01207.12 KFH43845.1 - 7.7e-39 133.3 0.0 1.2e-27 96.5 0.0 2.5 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 KFH43845.1 - 0.016 14.8 2.2 2.3 7.9 0.3 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Tom37_C PF11801.3 KFH43846.1 - 8.9e-22 77.7 0.0 1.2e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 KFH43846.1 - 9.8e-21 73.8 0.7 3.3e-19 68.9 0.0 2.8 3 0 0 3 3 3 1 Outer mitochondrial membrane transport complex protein GST_C_3 PF14497.1 KFH43846.1 - 0.0011 19.3 0.1 0.0028 18.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Oxygenase-NA PF09859.4 KFH43846.1 - 0.18 11.1 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA APG6 PF04111.7 KFH43847.1 - 1.6e-126 421.6 0.0 1.9e-126 421.3 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 zf-C4H2 PF10146.4 KFH43847.1 - 0.017 15.1 7.6 0.036 14.1 5.3 1.5 1 0 0 1 1 1 0 Zinc finger-containing protein DUF342 PF03961.8 KFH43847.1 - 0.018 13.4 3.2 0.024 13.0 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2252 PF10009.4 KFH43847.1 - 0.035 13.0 4.4 0.05 12.5 3.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) TMF_TATA_bd PF12325.3 KFH43847.1 - 0.05 13.3 11.1 0.049 13.3 5.8 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1732 PF08340.6 KFH43847.1 - 0.12 12.2 3.7 0.25 11.1 2.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) ERM PF00769.14 KFH43847.1 - 0.18 11.2 18.2 0.31 10.5 12.6 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Suppressor_APC PF11414.3 KFH43847.1 - 0.81 9.5 9.8 12 5.7 0.1 2.5 1 1 1 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein IncA PF04156.9 KFH43847.1 - 1.1 8.7 10.0 2.2 7.8 6.9 1.4 1 0 0 1 1 1 0 IncA protein DUF4140 PF13600.1 KFH43847.1 - 2 8.8 9.1 2 8.8 5.0 2.0 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) OmpH PF03938.9 KFH43847.1 - 7.5 6.4 17.0 11 5.9 4.8 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Ras PF00071.17 KFH43848.1 - 2.3e-58 196.1 0.1 2.7e-58 195.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFH43848.1 - 3.5e-19 69.4 0.1 6e-19 68.6 0.0 1.4 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 KFH43848.1 - 8.4e-15 54.4 0.0 1.1e-14 54.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFH43848.1 - 5.1e-08 32.3 0.0 6e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFH43848.1 - 1e-07 31.6 0.0 1.4e-07 31.1 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFH43848.1 - 1.3e-05 25.0 0.0 1.8e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KFH43848.1 - 0.051 12.7 0.3 0.21 10.7 0.0 2.0 2 1 0 3 3 3 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 KFH43848.1 - 0.054 13.6 0.1 4.3 7.4 0.0 2.5 1 1 1 2 2 2 0 AAA domain Amidase02_C PF12123.3 KFH43848.1 - 0.097 12.3 0.0 0.81 9.3 0.0 2.2 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase G-alpha PF00503.15 KFH43848.1 - 0.14 10.7 0.2 5.5 5.5 0.0 2.2 1 1 1 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.1 KFH43848.1 - 0.15 12.0 0.4 0.39 10.6 0.3 1.9 1 1 0 1 1 1 0 AAA ATPase domain DUF1719 PF08224.6 KFH43849.1 - 0.061 12.4 0.0 0.096 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) Cmc1 PF08583.5 KFH43849.1 - 0.16 11.7 5.0 0.37 10.5 3.5 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Bcr-Abl_Oligo PF09036.5 KFH43849.1 - 0.17 11.8 3.1 0.43 10.5 0.4 2.4 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DUF4376 PF14301.1 KFH43849.1 - 0.55 10.3 4.1 0.98 9.5 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4376) ABC_tran PF00005.22 KFH43850.1 - 2.8e-49 166.9 0.0 2.9e-29 102.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KFH43850.1 - 1.9e-28 99.6 22.7 6.9e-22 78.1 1.6 2.8 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 KFH43850.1 - 1e-08 34.7 0.0 0.0018 17.5 0.0 4.0 2 2 1 4 4 4 1 RecF/RecN/SMC N terminal domain T2SE PF00437.15 KFH43850.1 - 0.00049 19.0 0.0 0.18 10.6 0.0 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 KFH43850.1 - 0.00071 19.6 1.0 0.2 11.6 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 KFH43850.1 - 0.0016 17.8 0.4 0.24 10.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_21 PF13304.1 KFH43850.1 - 0.0018 18.3 0.1 5 6.9 0.0 3.6 4 0 0 4 4 4 1 AAA domain DUF258 PF03193.11 KFH43850.1 - 0.002 17.3 0.3 0.88 8.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 KFH43850.1 - 0.0021 17.5 2.1 1.1 8.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KFH43850.1 - 0.003 17.8 0.3 0.14 12.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KFH43850.1 - 0.005 17.3 0.1 5.9 7.4 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 KFH43850.1 - 0.0053 16.6 0.2 0.56 10.1 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KFH43850.1 - 0.0077 16.3 0.4 11 6.1 0.0 3.3 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.12 KFH43850.1 - 0.021 14.6 2.4 0.34 10.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF2075 PF09848.4 KFH43850.1 - 0.024 13.6 0.1 0.3 10.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.13 KFH43850.1 - 0.041 13.3 0.0 8.2 5.8 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family SbcCD_C PF13558.1 KFH43850.1 - 0.063 13.1 0.0 11 6.0 0.0 3.5 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit CbiA PF01656.18 KFH43850.1 - 0.064 12.6 0.3 4.7 6.5 0.0 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.1 KFH43850.1 - 0.083 12.4 0.1 14 5.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain TrwB_AAD_bind PF10412.4 KFH43850.1 - 0.24 9.9 0.7 6.9 5.1 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain PIG-U PF06728.8 KFH43852.1 - 3.7e-99 332.1 23.1 4.4e-99 331.9 16.0 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U HIG_1_N PF04588.8 KFH43855.1 - 3e-07 30.0 9.4 8.8e-07 28.5 2.2 2.5 2 0 0 2 2 2 2 Hypoxia induced protein conserved region Romo1 PF10247.4 KFH43855.1 - 0.05 13.8 2.0 0.096 12.8 1.4 1.5 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 GFA PF04828.9 KFH43856.1 - 1.2e-18 66.7 7.8 1.2e-09 37.9 1.1 2.4 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Pkinase PF00069.20 KFH43857.1 - 1e-64 218.1 0.0 1.7e-64 217.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH43857.1 - 1.7e-36 125.6 0.0 1.6e-31 109.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KFH43857.1 - 1.7e-05 23.9 0.0 0.01 14.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KFH43857.1 - 0.00023 20.9 0.1 0.00068 19.4 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KFH43857.1 - 0.062 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFH43857.1 - 0.069 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Mur_ligase_C PF02875.16 KFH43858.1 - 0.00081 19.3 0.0 0.0022 18.0 0.0 1.7 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Mur_ligase_M PF08245.7 KFH43858.1 - 0.0011 19.0 0.0 0.21 11.6 0.0 2.5 2 1 0 2 2 2 2 Mur ligase middle domain Atg14 PF10186.4 KFH43859.1 - 1.2e-76 257.6 0.0 1.4e-76 257.3 0.0 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 UBN_AB PF14075.1 KFH43859.1 - 0.028 14.0 1.4 0.045 13.4 1.0 1.2 1 0 0 1 1 1 0 Ubinuclein conserved middle domain Cluap1 PF10234.4 KFH43859.1 - 0.061 12.5 3.4 0.09 11.9 2.3 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Spc7 PF08317.6 KFH43859.1 - 0.14 10.7 4.0 0.21 10.2 2.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Esterase_phd PF10503.4 KFH43860.1 - 1.6e-25 89.6 1.0 2.5e-25 89.0 0.7 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KFH43860.1 - 6.2e-11 41.9 2.0 9e-11 41.3 1.4 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFH43860.1 - 6.5e-07 29.1 0.1 8.8e-07 28.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFH43860.1 - 0.001 19.0 0.1 0.0015 18.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KFH43860.1 - 0.0024 17.3 1.0 0.0054 16.1 0.7 1.5 1 1 0 1 1 1 1 Putative esterase Spc7_N PF15402.1 KFH43861.1 - 1.8e-228 760.9 68.1 5.3e-209 696.5 41.6 2.1 1 1 1 2 2 2 2 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 KFH43861.1 - 8.2e-114 379.6 4.3 1.4e-113 378.9 3.0 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.1 KFH43861.1 - 2.5e-20 71.8 0.2 4.5e-20 71.0 0.2 1.4 1 0 0 1 1 1 1 Spc7_C2 RTC_insert PF05189.8 KFH43861.1 - 0.015 15.3 0.0 0.065 13.2 0.0 2.1 1 0 0 1 1 1 0 RNA 3'-terminal phosphate cyclase (RTC), insert domain DivIC PF04977.10 KFH43861.1 - 0.022 14.2 1.6 0.078 12.4 1.1 1.9 1 0 0 1 1 1 0 Septum formation initiator GAS PF13851.1 KFH43861.1 - 0.067 12.3 3.8 0.17 11.0 2.6 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 KFH43861.1 - 3.2 7.3 15.7 0.21 11.1 6.5 2.3 2 0 0 2 2 2 0 IncA protein RRN9 PF10680.4 KFH43862.1 - 1.2e-14 53.8 0.2 5.1e-14 51.7 0.2 2.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor zf-C2H2_4 PF13894.1 KFH43862.1 - 0.083 13.2 0.6 0.24 11.8 0.4 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KFH43862.1 - 0.15 12.4 0.4 0.42 11.0 0.3 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type tRNA-synt_1 PF00133.17 KFH43863.1 - 1.4e-158 528.6 0.0 1.9e-158 528.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KFH43863.1 - 7.2e-24 84.1 0.1 5.5e-14 51.6 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KFH43863.1 - 5.5e-19 68.4 0.0 9.4e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.9 KFH43863.1 - 4.8e-05 22.8 2.4 9.4e-05 21.9 1.7 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.1 KFH43863.1 - 0.0092 15.2 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 KFH43863.1 - 0.14 11.2 0.2 8.3 5.4 0.0 2.5 2 1 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain DUF3807 PF12720.2 KFH43864.1 - 1.1e-34 120.1 0.4 1.3e-34 119.8 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) Spt5_N PF11942.3 KFH43864.1 - 0.0015 19.0 2.9 0.0031 18.0 2.0 1.5 1 0 0 1 1 1 1 Spt5 transcription elongation factor, acidic N-terminal WD40 PF00400.27 KFH43865.1 - 4e-28 96.2 10.9 3.1e-07 30.0 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KFH43865.1 - 0.00015 21.5 0.1 0.082 12.6 0.0 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 KFH43865.1 - 0.12 12.0 3.3 8.9 6.1 0.2 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Peroxin-13_N PF04088.8 KFH43866.1 - 2.9e-56 189.8 0.1 4.9e-56 189.0 0.0 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 KFH43866.1 - 2.2e-09 36.6 0.0 3.6e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFH43866.1 - 6.5e-08 31.8 0.0 1.1e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFH43866.1 - 3.2e-07 29.8 0.1 5.4e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Mitofilin PF09731.4 KFH43867.1 - 6.3e-147 490.7 8.3 9.4e-147 490.1 5.8 1.2 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Cas_DxTHG PF09455.5 KFH43867.1 - 0.25 10.4 2.9 0.43 9.6 2.0 1.3 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family Scm3 PF10384.4 KFH43868.1 - 1.9e-19 68.8 0.0 3.2e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Centromere protein Scm3 MSP1_C PF07462.6 KFH43868.1 - 1.1 7.5 3.3 1.6 6.9 2.3 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Syja_N PF02383.13 KFH43869.1 - 1e-88 297.1 0.2 1.3e-88 296.8 0.1 1.1 1 0 0 1 1 1 1 SacI homology domain AAA PF00004.24 KFH43870.1 - 9.9e-12 45.1 0.0 2e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFH43870.1 - 0.00057 19.9 0.1 0.0015 18.5 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFH43870.1 - 0.0038 17.3 0.1 0.021 14.9 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 KFH43870.1 - 0.013 15.2 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 KFH43870.1 - 0.021 14.5 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CPT PF07931.7 KFH43870.1 - 0.11 12.1 0.0 0.43 10.1 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein TIP49 PF06068.8 KFH43870.1 - 0.16 10.6 0.0 0.25 10.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus HSP20 PF00011.16 KFH43871.1 - 3.4e-17 62.1 0.1 3.4e-11 42.8 0.0 2.1 1 1 0 2 2 2 2 Hsp20/alpha crystallin family dCMP_cyt_deam_1 PF00383.17 KFH43872.1 - 2.7e-25 87.9 1.0 4.3e-25 87.3 0.7 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_18 PF13238.1 KFH43872.1 - 4e-05 23.9 0.2 0.068 13.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KFH43872.1 - 0.00012 22.9 0.2 0.0065 17.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain CoaE PF01121.15 KFH43872.1 - 0.034 13.5 0.1 0.1 11.9 0.0 1.8 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_33 PF13671.1 KFH43872.1 - 0.067 13.0 0.5 2.9 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF399 PF04187.8 KFH43873.1 - 0.046 13.2 0.2 0.11 11.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF399 PPR_2 PF13041.1 KFH43874.1 - 6.3e-06 26.0 0.0 0.0063 16.4 0.0 2.6 2 0 0 2 2 2 2 PPR repeat family PPR_3 PF13812.1 KFH43874.1 - 0.006 16.7 0.3 0.1 12.9 0.0 3.2 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR PF01535.15 KFH43874.1 - 0.029 14.3 0.1 1.3 9.1 0.0 2.7 2 0 0 2 2 2 0 PPR repeat FAD_binding_4 PF01565.18 KFH43875.1 - 1.8e-20 72.8 0.9 3.9e-20 71.7 0.6 1.6 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFH43875.1 - 0.0015 18.4 0.7 0.0033 17.2 0.5 1.7 1 0 0 1 1 1 1 Berberine and berberine like He_PIG PF05345.7 KFH43876.1 - 2.2e-11 43.5 6.1 0.00046 20.1 0.2 4.9 5 0 0 5 5 5 3 Putative Ig domain TMEM154 PF15102.1 KFH43876.1 - 1e-05 25.2 0.1 2.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.1 KFH43876.1 - 0.00022 20.7 0.0 0.0061 16.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) AJAP1_PANP_C PF15298.1 KFH43876.1 - 0.027 14.3 0.2 0.027 14.3 0.2 2.2 2 0 0 2 2 2 0 AJAP1/PANP C-terminus SKG6 PF08693.5 KFH43876.1 - 0.037 13.3 2.3 0.076 12.3 1.6 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3394 PF11874.3 KFH43876.1 - 0.083 12.4 0.7 0.33 10.4 0.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3394) RSN1_TM PF13967.1 KFH43876.1 - 0.1 12.1 0.2 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport Sarcoglycan_2 PF05510.8 KFH43876.1 - 0.1 10.8 0.0 0.22 9.7 0.0 1.5 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon DUF912 PF06024.7 KFH43876.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Herpes_gE PF02480.11 KFH43876.1 - 0.23 9.6 0.0 0.34 9.1 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Hum_adeno_E3A PF05393.6 KFH43876.1 - 0.29 10.8 1.4 0.62 9.7 1.0 1.5 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein Aconitase PF00330.15 KFH43877.1 - 3.7e-145 483.9 0.1 3e-144 480.9 0.1 1.9 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KFH43877.1 - 3.1e-41 140.5 0.0 5e-41 139.8 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain DPBB_1 PF03330.13 KFH43878.1 - 0.00072 19.5 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Orbi_VP6 PF01516.11 KFH43878.1 - 0.8 8.6 6.1 1.2 8.1 4.2 1.2 1 0 0 1 1 1 0 Orbivirus helicase VP6 PAT1 PF09770.4 KFH43878.1 - 4.2 5.4 11.9 5.2 5.1 8.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 4HBT_2 PF13279.1 KFH43879.1 - 0.00027 21.3 0.0 0.00044 20.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF3662 PF12401.3 KFH43880.1 - 0.069 13.3 0.0 0.075 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2662) Amino_oxidase PF01593.19 KFH43881.1 - 6.7e-45 153.9 0.1 2.6e-44 152.0 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KFH43881.1 - 3.9e-14 52.4 0.0 8.2e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KFH43881.1 - 9.1e-06 25.8 0.0 6.4e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFH43881.1 - 1.6e-05 24.7 0.7 0.012 15.3 0.0 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.19 KFH43881.1 - 3.1e-05 23.0 0.0 0.0021 17.0 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFH43881.1 - 3.3e-05 24.2 0.1 0.00012 22.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFH43881.1 - 4.9e-05 21.9 0.0 0.0023 16.4 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 KFH43881.1 - 0.00059 18.8 0.1 0.0012 17.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 KFH43881.1 - 0.004 16.2 0.1 0.0058 15.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KFH43881.1 - 0.0055 15.8 0.0 0.0091 15.1 0.0 1.2 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.13 KFH43881.1 - 0.0076 15.9 0.1 0.019 14.6 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KFH43881.1 - 0.011 15.7 0.1 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Pyr_redox_2 PF07992.9 KFH43881.1 - 0.016 15.1 0.0 0.043 13.7 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 KFH43881.1 - 0.21 10.9 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glyco_transf_8 PF01501.15 KFH43882.1 - 3.2e-26 92.1 0.0 6.3e-26 91.2 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 BAALC_N PF06989.7 KFH43882.1 - 0.3 11.4 2.6 3.7 7.9 0.0 2.5 2 0 0 2 2 2 0 BAALC N-terminus SAE2 PF08573.5 KFH43883.1 - 9.1e-26 90.3 0.2 9.1e-26 90.3 0.1 2.5 3 0 0 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Mito_carr PF00153.22 KFH43884.1 - 1.7e-69 229.5 0.0 3.9e-24 84.1 0.0 3.3 2 1 1 3 3 3 3 Mitochondrial carrier protein Acyl-CoA_dh_1 PF00441.19 KFH43885.1 - 9.2e-33 113.4 0.3 1.3e-32 112.9 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFH43885.1 - 1.7e-19 69.0 0.2 3.2e-19 68.1 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 KFH43885.1 - 2e-18 65.9 0.0 4.5e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 KFH43885.1 - 3.9e-06 27.4 0.2 1e-05 26.0 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KFH43885.1 - 0.00014 22.1 0.0 0.00025 21.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Pkinase PF00069.20 KFH43886.1 - 8.8e-41 139.7 0.0 2.3e-40 138.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH43886.1 - 1.5e-25 89.7 0.0 2.7e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH43886.1 - 0.032 13.2 0.0 0.055 12.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 KFH43886.1 - 0.19 10.8 0.0 1.1 8.2 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family ketoacyl-synt PF00109.21 KFH43887.1 - 6.4e-77 258.4 0.0 1.5e-76 257.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KFH43887.1 - 4.2e-58 197.1 1.9 5.5e-58 196.7 0.8 1.6 2 0 0 2 2 2 1 Acyl transferase domain KR PF08659.5 KFH43887.1 - 7.4e-51 172.3 0.1 2.5e-50 170.6 0.1 2.0 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 KFH43887.1 - 1.5e-44 152.3 0.0 3.1e-44 151.3 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KFH43887.1 - 2e-38 131.9 2.1 2.8e-38 131.4 0.3 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KFH43887.1 - 5e-38 129.5 0.1 9.8e-37 125.4 0.0 2.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KFH43887.1 - 1e-08 34.8 0.1 3.9e-08 32.9 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 KFH43887.1 - 0.0038 17.4 0.0 0.01 16.0 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KFH43887.1 - 0.023 13.6 0.3 0.061 12.3 0.1 1.7 2 0 0 2 2 2 0 Thiolase, N-terminal domain Zn_clus PF00172.13 KFH43888.1 - 6.4e-10 38.7 8.0 1.7e-09 37.4 5.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_23 PF13489.1 KFH43889.1 - 0.095 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain WD40 PF00400.27 KFH43890.1 - 1.9e-29 100.4 6.3 2.5e-07 30.3 0.2 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat Ank_2 PF12796.2 KFH43891.1 - 7.6e-56 186.4 13.9 1.4e-17 63.8 0.0 7.5 3 2 7 10 10 10 9 Ankyrin repeats (3 copies) Ank PF00023.25 KFH43891.1 - 2.8e-45 149.9 22.1 2.4e-08 33.3 0.0 13.8 13 2 0 13 13 13 11 Ankyrin repeat Ank_4 PF13637.1 KFH43891.1 - 4e-36 122.7 8.2 9.3e-08 32.3 0.0 11.6 7 3 5 13 13 13 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFH43891.1 - 4.7e-33 109.9 3.1 4.1e-05 23.4 0.0 13.6 14 1 1 15 15 15 6 Ankyrin repeat Ank_5 PF13857.1 KFH43891.1 - 3.5e-21 74.7 17.0 4.3e-07 29.9 0.1 11.2 7 3 8 15 15 15 8 Ankyrin repeats (many copies) DUF106 PF01956.11 KFH43892.1 - 0.12 11.9 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 adh_short PF00106.20 KFH43893.1 - 7.9e-27 94.2 0.0 1e-26 93.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH43893.1 - 7.1e-22 78.3 0.0 8.4e-22 78.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH43893.1 - 1.1e-07 31.7 0.0 1.6e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KFH43893.1 - 0.015 15.0 0.1 0.094 12.5 0.0 2.2 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KFH43893.1 - 0.028 13.8 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF2974 PF11187.3 KFH43893.1 - 0.033 13.5 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) UDPG_MGDP_dh_N PF03721.9 KFH43893.1 - 0.086 12.2 0.1 0.23 10.8 0.1 1.7 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF829 PF05705.9 KFH43894.1 - 3.2e-45 154.7 0.0 4.9e-45 154.0 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.2 KFH43894.1 - 0.0011 18.8 0.2 0.0067 16.3 0.0 1.9 1 1 0 2 2 2 1 Alpha/beta hydrolase family Complex1_LYR_2 PF13233.1 KFH43896.1 - 1.9e-18 66.8 0.0 2.3e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KFH43896.1 - 0.00083 19.1 0.2 0.0014 18.3 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Hormone_3 PF00159.13 KFH43896.1 - 0.23 11.4 1.9 0.31 11.1 0.5 1.8 2 0 0 2 2 2 0 Pancreatic hormone peptide Complex1_LYR_1 PF13232.1 KFH43896.1 - 0.37 11.0 3.7 0.57 10.4 2.6 1.6 1 1 0 1 1 1 0 Complex1_LYR-like Methyltransf_6 PF03737.10 KFH43897.1 - 2e-30 105.7 0.0 2.6e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase Adaptin_binding PF10199.4 KFH43898.1 - 0.018 15.2 0.3 0.076 13.2 0.0 2.1 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 MutS_III PF05192.13 KFH43898.1 - 0.24 11.1 3.3 0.36 10.5 2.3 1.2 1 0 0 1 1 1 0 MutS domain III CFEM PF05730.6 KFH43899.1 - 1.4e-09 37.6 8.7 2.3e-09 36.9 6.0 1.4 1 0 0 1 1 1 1 CFEM domain UL73_N PF12522.3 KFH43899.1 - 0.9 9.1 10.3 2 8.0 7.1 1.6 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal PP2C PF00481.16 KFH43900.1 - 4e-84 281.9 0.0 6.4e-84 281.3 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KFH43900.1 - 0.00038 19.9 0.0 0.0087 15.4 0.0 2.4 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.7 KFH43900.1 - 0.03 14.0 0.4 0.39 10.3 0.0 2.6 2 1 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) CDC45 PF02724.9 KFH43900.1 - 2.1 6.2 7.0 2.7 5.9 4.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DAO PF01266.19 KFH43901.1 - 4.6e-56 190.2 3.1 6.1e-56 189.8 2.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KFH43901.1 - 8.5e-05 22.6 0.0 0.077 13.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFH43901.1 - 0.00019 21.3 0.1 0.00042 20.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KFH43901.1 - 0.00061 18.3 0.1 0.047 12.1 0.0 2.6 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.14 KFH43901.1 - 0.00062 18.9 0.4 0.00092 18.3 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 KFH43901.1 - 0.00095 18.1 0.0 0.0016 17.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KFH43901.1 - 0.0013 18.6 0.0 0.011 15.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFH43901.1 - 0.0017 17.5 0.0 0.0028 16.8 0.0 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 KFH43901.1 - 0.19 11.4 1.5 3.1 7.5 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding E1-E2_ATPase PF00122.15 KFH43902.1 - 3.6e-70 235.5 6.6 6.3e-70 234.7 0.1 3.3 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 KFH43902.1 - 6.7e-22 78.9 0.0 2.6e-21 77.0 0.0 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFH43902.1 - 3.4e-12 46.9 0.0 7.2e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFH43902.1 - 3.7e-10 39.1 0.2 2.5e-09 36.4 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KFH43902.1 - 0.00096 18.7 0.1 0.0023 17.5 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase FGGY_C PF02782.11 KFH43902.1 - 0.024 14.2 0.3 0.047 13.3 0.2 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Hydrolase_like2 PF13246.1 KFH43902.1 - 0.048 13.6 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Methyltransf_16 PF10294.4 KFH43903.1 - 7.5e-43 145.9 0.0 9.7e-43 145.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 KFH43903.1 - 0.0037 16.8 0.0 0.0052 16.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFH43903.1 - 0.023 14.0 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.1 KFH43903.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF1712 PF08217.6 KFH43904.1 - 1.4e-10 40.1 0.0 1.4e-09 36.7 0.0 2.3 2 1 0 2 2 2 1 Fungal domain of unknown function (DUF1712) PAP1 PF08601.5 KFH43904.1 - 0.087 12.4 10.7 0.15 11.7 7.4 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 SAM_1 PF00536.25 KFH43904.1 - 0.12 12.5 0.1 0.46 10.6 0.0 1.9 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) GET2 PF08690.5 KFH43904.1 - 5.8 6.0 5.7 13 4.8 4.0 1.5 1 0 0 1 1 1 0 GET complex subunit GET2 NmrA PF05368.8 KFH43905.1 - 9.8e-16 57.7 0.0 1.4e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFH43905.1 - 4.5e-14 52.8 0.2 8e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KFH43905.1 - 4.7e-08 32.4 0.1 5.9e-08 32.0 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase F420_oxidored PF03807.12 KFH43905.1 - 0.00013 22.3 0.1 0.00027 21.3 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 KFH43905.1 - 0.00035 20.8 0.4 0.0012 19.1 0.2 1.9 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 KFH43905.1 - 0.00046 19.7 0.0 0.00064 19.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KFH43905.1 - 0.0033 17.3 0.5 0.0068 16.3 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KFH43905.1 - 0.0053 16.4 0.1 0.0092 15.6 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 KFH43905.1 - 0.0056 15.6 0.0 0.038 12.9 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein TrkA_N PF02254.13 KFH43905.1 - 0.082 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 KFH43905.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DapB_N PF01113.15 KFH43905.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ATG2_CAD PF13329.1 KFH43906.1 - 1.2e-48 164.6 0.1 2.4e-48 163.6 0.1 1.5 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 KFH43906.1 - 6.2e-25 87.2 0.2 2.5e-24 85.2 0.0 2.3 2 0 0 2 2 2 1 ATG C terminal domain UCH PF00443.24 KFH43907.1 - 2.8e-47 161.0 0.0 6.9e-47 159.8 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFH43907.1 - 3.6e-19 69.3 0.0 7e-19 68.3 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RRP7 PF12923.2 KFH43907.1 - 1.8 8.6 6.5 0.27 11.2 0.7 2.4 3 0 0 3 3 3 0 Ribosomal RNA-processing protein 7 (RRP7) UCR_14kD PF02271.11 KFH43908.1 - 4.7e-43 145.2 1.7 5.3e-43 145.0 1.2 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Angiomotin_C PF12240.3 KFH43908.1 - 0.0085 15.6 0.6 0.011 15.2 0.4 1.0 1 0 0 1 1 1 1 Angiomotin C terminal ASL_C PF08328.6 KFH43908.1 - 0.045 13.5 0.2 0.064 13.0 0.1 1.4 1 1 0 1 1 1 0 Adenylosuccinate lyase C-terminal She9_MDM33 PF05546.6 KFH43908.1 - 0.075 12.5 0.3 0.084 12.4 0.2 1.1 1 0 0 1 1 1 0 She9 / Mdm33 family LRR19-TM PF15176.1 KFH43908.1 - 0.093 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain zf-CCHC PF00098.18 KFH43909.1 - 8.1e-27 91.8 48.6 5.5e-08 32.3 2.3 6.1 5 1 0 5 5 5 4 Zinc knuckle zf-CCHC_4 PF14392.1 KFH43909.1 - 9.8e-07 28.3 28.2 0.0029 17.2 0.2 4.8 5 0 0 5 5 5 4 Zinc knuckle zf-CCHC_3 PF13917.1 KFH43909.1 - 0.00012 21.7 25.0 0.11 12.2 1.1 4.5 3 2 1 4 4 4 3 Zinc knuckle zf-CCHC_6 PF15288.1 KFH43909.1 - 0.081 12.6 38.6 0.45 10.2 0.6 5.3 3 2 2 5 5 5 0 Zinc knuckle zf-CCHC_5 PF14787.1 KFH43909.1 - 2.2 7.8 19.8 0.46 10.0 1.4 3.5 3 1 0 3 3 3 0 GAG-polyprotein viral zinc-finger bZIP_1 PF00170.16 KFH43910.1 - 5.5e-09 35.8 5.1 5.5e-09 35.8 3.5 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KFH43910.1 - 0.0002 21.0 6.5 0.0002 21.0 4.5 2.0 2 0 0 2 2 2 1 Basic region leucine zipper SNAPc19 PF15497.1 KFH43910.1 - 0.00053 20.1 1.2 0.00069 19.7 0.1 1.8 2 0 0 2 2 2 1 snRNA-activating protein complex subunit 19, SNAPc subunit 19 bZIP_Maf PF03131.12 KFH43910.1 - 0.15 12.3 7.7 0.058 13.6 3.2 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor DivIC PF04977.10 KFH43910.1 - 0.32 10.5 1.9 0.75 9.3 1.3 1.6 1 0 0 1 1 1 0 Septum formation initiator Macoilin PF09726.4 KFH43910.1 - 1.5 7.0 8.3 1.8 6.7 5.8 1.0 1 0 0 1 1 1 0 Transmembrane protein NAM-associated PF14303.1 KFH43910.1 - 6 7.1 11.8 13 6.1 8.1 1.5 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain PGA2 PF07543.7 KFH43910.1 - 7.8 6.2 8.3 11 5.7 5.7 1.4 1 1 0 1 1 1 0 Protein trafficking PGA2 Abhydrolase_6 PF12697.2 KFH43911.1 - 9.2e-31 107.4 0.1 1.3e-30 106.9 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH43911.1 - 3.2e-14 52.9 0.0 6.2e-14 51.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFH43911.1 - 0.00035 20.1 0.0 0.00059 19.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 KFH43911.1 - 0.064 12.6 0.0 0.15 11.5 0.0 1.6 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DUF3089 PF11288.3 KFH43911.1 - 0.2 10.7 0.6 0.31 10.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) Shisa PF13908.1 KFH43912.1 - 0.061 13.4 2.7 2.1 8.4 0.6 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator ADH_N PF08240.7 KFH43913.1 - 2.2e-23 82.0 4.4 3.6e-23 81.3 3.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFH43913.1 - 9.2e-16 57.5 0.0 3.5e-15 55.7 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFH43913.1 - 0.00068 20.5 0.0 0.0014 19.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KFH43913.1 - 0.0095 15.1 0.1 0.019 14.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HAD_2 PF13419.1 KFH43914.1 - 7.1e-27 94.7 0.0 9.6e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase TilS PF09179.6 KFH43914.1 - 0.12 12.3 0.7 0.49 10.4 0.0 2.2 3 0 0 3 3 3 0 TilS substrate binding domain MNNL PF07657.8 KFH43915.1 - 0.0012 18.7 0.7 0.0018 18.1 0.5 1.3 1 0 0 1 1 1 1 N terminus of Notch ligand DHODB_Fe-S_bind PF10418.4 KFH43915.1 - 0.43 10.1 5.5 3.4 7.2 0.1 2.5 2 0 0 2 2 2 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Cupin_1 PF00190.17 KFH43916.1 - 1.8e-08 33.9 0.3 2.4e-08 33.5 0.2 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 KFH43916.1 - 4.7e-07 29.2 0.9 8.4e-07 28.3 0.6 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 KFH43916.1 - 0.00024 20.7 0.2 0.00031 20.4 0.1 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 KFH43916.1 - 0.0079 15.8 0.2 0.012 15.2 0.1 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain DEAD PF00270.24 KFH43917.1 - 5.8e-46 156.0 0.0 9.4e-44 148.8 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KFH43917.1 - 8.8e-29 99.2 0.0 1.8e-28 98.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFH43917.1 - 9.6e-05 22.2 0.0 0.00031 20.6 0.0 1.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 KFH43917.1 - 0.00056 18.4 0.0 0.03 12.7 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1253) Helicase_C_2 PF13307.1 KFH43917.1 - 0.003 17.5 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain DUF2443 PF10398.4 KFH43917.1 - 0.011 15.4 0.7 0.024 14.4 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) Glyoxalase_3 PF13468.1 KFH43917.1 - 0.098 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Glyoxalase-like domain AAA_22 PF13401.1 KFH43917.1 - 0.27 11.3 0.8 4.7 7.3 0.1 2.8 1 1 1 2 2 2 0 AAA domain His_Phos_1 PF00300.17 KFH43918.1 - 1.7e-20 73.7 0.1 2e-20 73.4 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) tRNA-synt_1c PF00749.16 KFH43919.1 - 9.4e-87 290.5 0.0 1.2e-86 290.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Herpes_gE PF02480.11 KFH43920.1 - 0.014 13.7 1.2 0.11 10.7 0.0 2.4 3 0 0 3 3 3 0 Alphaherpesvirus glycoprotein E DUF3382 PF11862.3 KFH43920.1 - 0.13 12.1 0.1 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) PP2C PF00481.16 KFH43922.1 - 9.8e-59 198.8 0.9 2.7e-48 164.6 0.4 3.1 2 1 1 3 3 3 2 Protein phosphatase 2C Ribosomal_60s PF00428.14 KFH43922.1 - 0.016 15.5 5.0 0.016 15.5 3.4 3.5 4 0 0 4 4 4 0 60s Acidic ribosomal protein DnaJ PF00226.26 KFH43923.1 - 3.6e-24 84.2 4.6 7.7e-24 83.2 3.2 1.6 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KFH43923.1 - 5.3e-19 67.8 0.1 5.9e-17 61.3 0.0 2.9 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KFH43923.1 - 2.4e-13 49.9 17.8 4.2e-13 49.1 12.3 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KFH43923.1 - 0.015 14.9 6.5 0.13 11.9 0.7 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Malate_DH PF12434.3 KFH43923.1 - 0.05 13.3 0.2 0.12 12.1 0.1 1.7 1 0 0 1 1 1 0 Malate dehydrogenase enzyme UreE_N PF02814.10 KFH43923.1 - 0.12 11.9 0.1 0.29 10.6 0.0 1.7 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain zf-CHY PF05495.7 KFH43923.1 - 1.5 9.0 6.7 2.3 8.4 0.4 2.4 2 0 0 2 2 2 0 CHY zinc finger DUF1356 PF07092.7 KFH43923.1 - 4 6.5 6.6 2.9 7.0 0.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1356) PDH PF02153.12 KFH43924.1 - 1.1e-15 57.1 0.0 1.6e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.12 KFH43924.1 - 5.7e-07 29.8 0.0 1.4e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 KFH43924.1 - 2.4e-06 27.4 0.0 4.6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 KFH43924.1 - 4e-05 22.8 0.0 6.5e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 KFH43924.1 - 0.002 17.6 0.0 0.0036 16.7 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 KFH43924.1 - 0.009 15.6 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 KFH43924.1 - 0.014 15.3 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.15 KFH43924.1 - 0.086 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sod_Cu PF00080.15 KFH43925.1 - 3.4e-11 43.4 0.0 5.5e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.21 KFH43925.1 - 6.3e-11 42.2 0.1 1.1e-10 41.4 0.1 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain Glyco_hydro_47 PF01532.15 KFH43926.1 - 2.4e-156 520.9 0.0 2.8e-156 520.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 SH3_1 PF00018.23 KFH43927.1 - 1.8e-05 24.0 0.0 3.4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFH43927.1 - 0.0068 15.9 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Uricase PF01014.13 KFH43928.1 - 6.9e-87 288.5 1.3 8.7e-47 158.6 0.4 2.0 2 0 0 2 2 2 2 Uricase Ribosomal_L32e PF01655.13 KFH43931.1 - 1.1e-49 167.1 1.1 1.1e-49 167.1 0.8 1.3 2 0 0 2 2 2 1 Ribosomal protein L32 Rad9 PF04139.8 KFH43932.1 - 1.9e-60 204.0 0.0 2.3e-60 203.8 0.0 1.1 1 0 0 1 1 1 1 Rad9 MCPVI PF02993.9 KFH43932.1 - 4.3 7.4 6.1 6.8 6.7 4.2 1.3 1 0 0 1 1 1 0 Minor capsid protein VI AMP-binding PF00501.23 KFH43933.1 - 2.4e-52 177.7 0.0 3.1e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFH43933.1 - 9.5e-06 26.4 0.1 4.5e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF2244 PF10003.4 KFH43933.1 - 0.37 10.1 1.6 0.74 9.1 1.1 1.4 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Ran_BP1 PF00638.13 KFH43934.1 - 1e-49 167.6 0.7 1.6e-49 166.9 0.5 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 KFH43934.1 - 0.0045 16.6 0.1 0.014 15.1 0.1 1.7 1 1 0 1 1 1 1 WH1 domain CDC27 PF09507.5 KFH43934.1 - 0.25 10.5 17.8 0.36 10.0 12.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 EAP30 PF04157.11 KFH43935.1 - 7.8e-63 211.6 0.0 9e-63 211.4 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Zn_clus PF00172.13 KFH43936.1 - 4.5e-07 29.6 12.0 7.3e-07 28.9 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Chitin_synth_2 PF03142.10 KFH43937.1 - 3.4e-38 131.3 5.0 3.9e-30 104.7 1.3 2.2 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KFH43937.1 - 3.1e-09 36.8 10.2 3.1e-09 36.8 3.4 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 KFH43937.1 - 7.5e-08 32.2 0.0 0.00054 19.6 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KFH43937.1 - 0.00023 21.0 0.4 0.0071 16.1 0.1 2.8 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Phosducin PF02114.11 KFH43938.1 - 2.2e-07 29.9 0.0 6e-06 25.1 0.0 2.2 1 1 1 2 2 2 2 Phosducin DUF2847 PF11009.3 KFH43938.1 - 0.018 14.5 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) AAR2 PF05282.6 KFH43939.1 - 2e-47 161.8 0.0 3e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 AAR2 protein Baculo_p74_N PF08404.5 KFH43939.1 - 0.02 13.6 0.0 0.031 13.0 0.0 1.2 1 0 0 1 1 1 0 Baculoviridae P74 N-terminal Tom22 PF04281.8 KFH43940.1 - 1.9e-46 157.0 0.1 2.3e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Aminotran_1_2 PF00155.16 KFH43941.1 - 2.7e-55 187.7 0.0 3.8e-55 187.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KFH43941.1 - 0.05 12.6 0.0 0.094 11.7 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family CSS-motif PF12792.2 KFH43941.1 - 0.053 12.8 0.0 0.12 11.6 0.0 1.6 1 0 0 1 1 1 0 CSS motif domain associated with EAL Phos_pyr_kin PF08543.7 KFH43942.1 - 1.4e-83 279.8 0.1 2e-83 279.4 0.1 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 KFH43942.1 - 2.5e-43 148.2 0.3 3.3e-43 147.9 0.2 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 KFH43942.1 - 2.8e-07 29.9 0.1 4.9e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase CbiX PF01903.12 KFH43942.1 - 0.12 12.5 0.2 0.63 10.1 0.1 2.3 2 1 0 2 2 2 0 CbiX UDPG_MGDP_dh_N PF03721.9 KFH43943.1 - 3.6e-22 78.6 0.0 3.9e-20 72.0 0.0 2.2 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 KFH43943.1 - 2.6e-18 66.0 0.0 4.8e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.10 KFH43943.1 - 0.0036 17.1 0.0 0.0059 16.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 KFH43943.1 - 0.017 15.0 0.0 0.052 13.5 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain UDPG_MGDP_dh_C PF03720.10 KFH43943.1 - 0.094 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain ELFV_dehydrog PF00208.16 KFH43944.1 - 4.3e-58 196.7 0.0 7e-58 196.0 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 KFH43944.1 - 1.3e-22 79.1 0.0 3.6e-17 61.1 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 KFH43944.1 - 0.00023 20.7 0.0 0.00079 19.0 0.0 1.9 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Dynamin_N PF00350.18 KFH43946.1 - 3.5e-17 62.7 0.7 6.1e-17 61.9 0.0 1.8 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 KFH43946.1 - 9.4e-10 38.4 0.0 3.5e-09 36.6 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFH43946.1 - 2.9e-06 26.8 0.4 3.4e-05 23.3 0.3 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 KFH43946.1 - 0.0045 17.2 0.0 0.013 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 KFH43946.1 - 0.029 13.8 0.0 0.071 12.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.1 KFH43946.1 - 0.043 13.3 0.0 0.043 13.3 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain FlgN PF05130.7 KFH43946.1 - 0.057 13.6 1.7 0.21 11.8 1.2 1.9 1 0 0 1 1 1 0 FlgN protein TPR_1 PF00515.23 KFH43947.1 - 6.1e-17 60.4 2.5 5.3e-08 32.1 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFH43947.1 - 3.3e-16 58.6 2.1 5.2e-11 42.0 0.1 3.3 1 1 2 3 3 3 2 TPR repeat TPR_2 PF07719.12 KFH43947.1 - 8.7e-16 56.5 3.3 3.5e-06 26.5 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFH43947.1 - 2.1e-13 50.0 0.4 6.1e-08 32.4 0.0 2.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFH43947.1 - 6.1e-12 44.4 0.6 3.7e-05 23.1 0.0 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFH43947.1 - 8.6e-09 34.5 0.4 6.8e-07 28.6 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFH43947.1 - 9.9e-09 35.0 0.2 0.21 12.1 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat PB1 PF00564.19 KFH43947.1 - 5.3e-07 29.2 0.1 9.2e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 PB1 domain TPR_17 PF13431.1 KFH43947.1 - 2.5e-06 27.2 0.2 0.018 15.2 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFH43947.1 - 3.1e-06 27.7 1.8 0.00085 19.9 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFH43947.1 - 9.1e-05 22.7 0.8 0.029 14.9 0.0 3.6 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFH43947.1 - 0.00041 20.1 0.2 0.47 10.3 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_4 PF07721.9 KFH43947.1 - 0.0067 16.7 0.2 37 5.1 0.0 4.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 KFH43947.1 - 0.049 13.5 0.4 2 8.4 0.0 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 KFH43947.1 - 0.073 13.2 0.3 0.073 13.2 0.2 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 RCC1 PF00415.13 KFH43948.1 - 1.6e-23 82.6 19.0 3.8e-10 39.8 0.0 6.8 6 1 1 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KFH43948.1 - 4.8e-21 73.8 23.5 2.9e-07 29.8 0.5 5.6 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat IRS PF02174.12 KFH43948.1 - 0.073 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 PTB domain (IRS-1 type) Ribosomal_L13 PF00572.13 KFH43949.1 - 2.3e-41 140.8 0.0 3.1e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Rod-binding PF10135.4 KFH43950.1 - 0.022 14.7 0.0 0.074 13.0 0.0 1.8 2 0 0 2 2 2 0 Rod binding protein Ribosomal_S9 PF00380.14 KFH43951.1 - 4.6e-40 136.6 0.2 5.2e-40 136.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Nckap1 PF09735.4 KFH43951.1 - 0.02 12.4 0.0 0.023 12.2 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein RICTOR_N PF14664.1 KFH43952.1 - 3.6e-139 463.4 0.2 7.6e-138 459.1 0.1 2.4 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 KFH43952.1 - 3.4e-90 301.0 0.0 2.5e-89 298.1 0.0 2.3 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 KFH43952.1 - 7.7e-42 141.8 0.0 2.7e-40 136.8 0.0 3.0 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 KFH43952.1 - 7e-29 99.5 0.1 2e-26 91.7 0.0 4.0 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 KFH43952.1 - 1.3e-12 47.3 4.2 2.7e-12 46.2 2.9 1.6 1 0 0 1 1 1 1 Hr1 repeat Uds1 PF15456.1 KFH43952.1 - 0.0016 18.4 6.6 0.0049 16.8 4.5 1.8 1 0 0 1 1 1 1 Up-regulated During Septation HEAT_2 PF13646.1 KFH43952.1 - 0.024 14.9 5.8 2.3 8.5 0.0 5.1 6 0 0 6 6 6 0 HEAT repeats SlyX PF04102.7 KFH43952.1 - 0.36 11.2 3.6 0.32 11.3 1.0 2.2 2 0 0 2 2 2 0 SlyX DUF1183 PF06682.7 KFH43952.1 - 7.4 6.0 8.8 17 4.8 6.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) WD40 PF00400.27 KFH43953.1 - 1.9e-47 157.5 20.9 1.3e-09 37.5 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KFH43953.1 - 0.00013 21.7 0.0 0.089 12.4 0.0 2.8 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Glyco_hydro_18 PF00704.23 KFH43954.1 - 1.8e-72 244.6 0.0 2.1e-72 244.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GHL6 PF14871.1 KFH43954.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 YEATS PF03366.11 KFH43955.1 - 2.9e-20 71.7 0.1 5.9e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 YEATS family Med10 PF09748.4 KFH43955.1 - 0.026 14.3 0.1 0.075 12.8 0.1 1.8 1 1 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex Snf7 PF03357.16 KFH43957.1 - 3.9e-36 124.0 19.9 3.9e-36 124.0 13.8 1.3 2 0 0 2 2 2 1 Snf7 V_ATPase_I PF01496.14 KFH43957.1 - 0.0044 14.9 2.8 0.0053 14.6 1.9 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CaMBD PF02888.11 KFH43957.1 - 0.032 14.0 3.0 0.032 14.0 2.1 2.1 1 1 1 2 2 2 0 Calmodulin binding domain Ist1 PF03398.9 KFH43957.1 - 0.14 11.5 7.0 0.22 10.9 4.8 1.3 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway PspA_IM30 PF04012.7 KFH43957.1 - 0.87 8.8 16.4 1.4 8.1 3.7 2.1 1 1 0 2 2 2 0 PspA/IM30 family Mpv17_PMP22 PF04117.7 KFH43959.1 - 1.8e-12 46.6 2.1 1.1e-11 44.1 1.4 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family Serinc PF03348.10 KFH43959.1 - 0.054 12.2 2.3 0.074 11.7 1.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Pyr_redox_2 PF07992.9 KFH43960.1 - 1.5e-25 90.2 0.0 1.1e-24 87.4 0.0 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFH43960.1 - 1.2e-14 54.4 0.0 3.5e-12 46.5 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFH43960.1 - 0.0013 18.8 0.2 1.6 8.7 0.1 3.0 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KFH43960.1 - 0.002 18.3 0.1 1.5 9.1 0.0 2.9 3 0 0 3 3 3 2 Putative NAD(P)-binding ketoacyl-synt PF00109.21 KFH43961.1 - 3.5e-60 203.6 0.2 6.6e-60 202.7 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KFH43961.1 - 6.1e-60 201.9 0.5 6.1e-60 201.9 0.4 2.6 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.16 KFH43961.1 - 1.1e-53 182.6 0.0 1.9e-53 181.8 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KFH43961.1 - 1.7e-47 161.9 0.0 3.1e-47 161.1 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KFH43961.1 - 4.7e-45 153.5 0.3 4.7e-45 153.5 0.2 3.3 4 0 0 4 4 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KFH43961.1 - 2.8e-38 130.4 0.3 7.5e-38 129.0 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KFH43961.1 - 7.8e-23 80.4 0.0 2.9e-22 78.6 0.0 2.1 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KFH43961.1 - 4.5e-17 62.3 0.0 1.7e-16 60.5 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH43961.1 - 1.6e-14 53.9 0.0 4.5e-14 52.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH43961.1 - 1.7e-11 44.4 0.0 5.5e-11 42.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 KFH43961.1 - 7.8e-10 38.4 0.2 2.1e-09 37.1 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_31 PF13847.1 KFH43961.1 - 7.2e-09 35.3 0.0 2.2e-08 33.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KFH43961.1 - 8.8e-09 36.3 0.0 6.4e-08 33.5 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 KFH43961.1 - 2.6e-08 34.4 0.0 1.8e-07 31.7 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 KFH43961.1 - 0.0004 20.5 0.0 0.00092 19.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.13 KFH43961.1 - 0.00099 18.2 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 KFH43961.1 - 0.0082 15.6 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase SPOC PF07744.8 KFH43962.1 - 4.3e-20 72.3 0.0 9.2e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.9 KFH43962.1 - 5.3e-15 55.4 0.1 5.3e-15 55.4 0.1 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.24 KFH43962.1 - 1e-08 34.7 9.8 1.9e-08 33.8 6.8 1.5 1 0 0 1 1 1 1 PHD-finger ECIST_Cterm PF14784.1 KFH43962.1 - 0.051 13.5 0.7 0.15 12.0 0.5 1.8 1 0 0 1 1 1 0 C-terminal domain of the ECSIT protein ADH_N PF08240.7 KFH43963.1 - 1.4e-23 82.6 0.3 1.4e-23 82.6 0.2 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFH43963.1 - 1.8e-19 69.5 0.0 2.7e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KFH43963.1 - 0.035 13.2 0.1 0.058 12.5 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 KFH43963.1 - 0.053 13.1 0.2 0.074 12.6 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans PF04082.13 KFH43964.1 - 3.9e-16 58.7 0.0 6.7e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SP_C-Propep PF08999.5 KFH43964.1 - 0.025 14.0 2.4 0.056 12.9 1.7 1.5 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide zf-C2H2_jaz PF12171.3 KFH43965.1 - 0.0002 21.3 0.4 0.00035 20.6 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding V_ATPase_I PF01496.14 KFH43965.1 - 0.54 8.0 1.9 0.73 7.6 1.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3439 PF11921.3 KFH43965.1 - 0.67 9.7 7.1 1.7 8.3 4.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) IncA PF04156.9 KFH43965.1 - 5.2 6.6 7.7 11 5.5 5.4 1.5 1 0 0 1 1 1 0 IncA protein DUF3408 PF11888.3 KFH43966.1 - 0.005 16.7 0.1 0.0052 16.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3408) LAMTOR PF15454.1 KFH43967.1 - 2e-12 47.1 0.0 3.2e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Sugar_tr PF00083.19 KFH43968.1 - 4.2e-85 286.0 13.0 4.8e-85 285.8 9.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH43968.1 - 2.5e-31 108.7 16.5 3.3e-31 108.2 11.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KFH43968.1 - 2.6e-08 32.5 4.1 5.4e-08 31.4 1.5 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 KFH43968.1 - 2.5e-05 22.8 1.2 2.5e-05 22.8 0.8 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein Cas1_AcylT PF07779.7 KFH43969.1 - 1.1e-110 370.3 18.8 4.4e-109 365.1 13.0 2.6 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.1 KFH43969.1 - 1.1e-14 54.9 0.0 6.2e-14 52.4 0.0 2.0 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p SLT PF01464.15 KFH43970.1 - 0.0054 16.2 0.9 0.038 13.4 0.6 2.1 1 1 0 1 1 1 1 Transglycosylase SLT domain SLT_2 PF13406.1 KFH43970.1 - 0.045 12.6 0.0 0.075 11.9 0.0 1.2 1 0 0 1 1 1 0 Transglycosylase SLT domain Lysozyme_like PF13702.1 KFH43970.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Lysozyme-like Hydrophobin_2 PF06766.6 KFH43971.1 - 1.4e-26 91.9 9.6 1.7e-26 91.6 6.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin K_oxygenase PF13434.1 KFH43972.1 - 2.1e-108 362.2 0.0 2.5e-108 362.0 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KFH43972.1 - 1.3e-09 38.4 0.0 4.2e-08 33.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFH43972.1 - 1.6e-08 34.4 0.0 1.9e-06 27.7 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KFH43972.1 - 6.8e-06 26.1 0.0 9.8e-05 22.3 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DUF4147 PF13660.1 KFH43972.1 - 0.038 13.1 0.0 4.8 6.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) Glyco_hydro_43 PF04616.9 KFH43973.1 - 0.0023 17.0 0.3 0.0047 16.0 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 BNR PF02012.15 KFH43973.1 - 0.0096 15.5 0.1 8.3 6.7 0.0 3.3 2 0 0 2 2 2 2 BNR/Asp-box repeat Trypan_PARP PF05887.6 KFH43974.1 - 0.15 11.8 3.0 0.27 11.0 2.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Glyco_transf_15 PF01793.11 KFH43975.1 - 3.1e-39 134.8 0.0 3.9e-23 81.9 0.0 2.5 2 1 1 3 3 3 2 Glycolipid 2-alpha-mannosyltransferase AMP-binding PF00501.23 KFH43976.1 - 1.9e-240 797.3 0.0 9.3e-87 291.1 0.0 3.5 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 KFH43976.1 - 8.6e-166 550.1 0.0 2.3e-34 118.6 0.0 7.6 7 0 0 7 7 7 7 Condensation domain PP-binding PF00550.20 KFH43976.1 - 2.5e-55 184.6 7.1 2.2e-10 40.6 0.0 7.1 7 0 0 7 7 7 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KFH43976.1 - 4.6e-21 75.5 0.0 3e-07 31.2 0.0 4.1 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain Transferase PF02458.10 KFH43976.1 - 8.7e-07 27.7 0.0 0.38 9.1 0.0 4.7 5 0 0 5 5 5 2 Transferase family WES_acyltransf PF03007.11 KFH43976.1 - 3e-05 23.7 0.6 1.2 8.6 0.0 4.6 5 0 0 5 5 5 2 Wax ester synthase-like Acyl-CoA acyltransferase domain GMP_synt_C PF00958.17 KFH43976.1 - 0.02 14.5 0.0 1.6 8.4 0.0 2.7 2 0 0 2 2 2 0 GMP synthase C terminal domain AATase PF07247.7 KFH43976.1 - 0.037 12.5 0.3 16 3.8 0.0 4.2 6 0 0 6 6 6 0 Alcohol acetyltransferase TFIIE_alpha PF02002.12 KFH43976.1 - 3.2 7.3 0.7 19 4.8 0.1 2.3 1 1 1 2 2 2 0 TFIIE alpha subunit HET PF06985.6 KFH43977.1 - 2e-19 70.1 7.1 8.5e-18 64.8 0.2 2.8 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) GMC_oxred_N PF00732.14 KFH43978.1 - 2.8e-52 177.7 0.0 3.6e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFH43978.1 - 5.5e-38 130.4 0.0 9.2e-38 129.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KFH43978.1 - 6e-05 22.1 0.1 9e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KFH43978.1 - 0.00011 22.1 0.1 0.0003 20.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KFH43978.1 - 0.00033 19.6 0.0 0.13 11.0 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KFH43978.1 - 0.00037 19.5 0.2 0.0027 16.6 0.0 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KFH43978.1 - 0.016 13.8 0.0 0.023 13.3 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.9 KFH43978.1 - 0.041 12.3 0.0 0.099 11.0 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.22 KFH43978.1 - 0.099 13.0 0.1 1.2 9.5 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFH43978.1 - 0.099 12.5 0.0 0.29 11.0 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.20 KFH43979.1 - 5.2e-12 45.4 0.0 6e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH43979.1 - 0.00097 18.2 0.0 0.0012 17.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Cyclase PF04199.8 KFH43981.1 - 7.2e-19 68.1 2.8 1.1e-18 67.5 1.8 1.3 1 1 0 1 1 1 1 Putative cyclase Proteasome PF00227.21 KFH43982.1 - 3.6e-61 205.7 0.1 4.3e-61 205.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KFH43982.1 - 3e-14 52.0 0.2 6.9e-14 50.8 0.1 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.9 KFH43982.1 - 0.16 11.2 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Med7 PF05983.6 KFH43983.1 - 3e-46 157.1 0.0 3.6e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 MED7 protein FAD_binding_2 PF00890.19 KFH43984.1 - 8.6e-71 238.9 0.0 1.3e-70 238.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KFH43984.1 - 1e-08 34.6 0.3 1.7e-08 33.9 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KFH43984.1 - 2.8e-05 22.7 0.1 4.1e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 KFH43984.1 - 8.2e-05 22.5 0.5 0.00025 20.9 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFH43984.1 - 0.00028 20.8 0.0 0.0017 18.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KFH43984.1 - 0.0012 17.8 3.2 0.0043 16.0 2.0 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 KFH43984.1 - 0.003 16.6 0.1 0.0058 15.7 0.1 1.4 1 0 0 1 1 1 1 Thi4 family F-box PF00646.28 KFH43985.1 - 7.4e-08 31.8 0.2 7.4e-08 31.8 0.1 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KFH43985.1 - 4.5e-07 29.4 0.3 4.5e-07 29.4 0.2 2.2 2 0 0 2 2 2 1 F-box-like RPEL PF02755.10 KFH43985.1 - 0.01 15.1 0.0 0.048 13.0 0.0 2.1 2 0 0 2 2 2 0 RPEL repeat Taxilin PF09728.4 KFH43986.1 - 0.064 12.3 0.7 0.082 11.9 0.5 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein GlgS PF08971.6 KFH43986.1 - 0.4 10.6 4.0 1.5 8.8 0.0 2.2 2 0 0 2 2 2 0 Glycogen synthesis protein Aldedh PF00171.17 KFH43988.1 - 1.8e-149 498.0 0.0 2.1e-149 497.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MFS_1 PF07690.11 KFH43989.1 - 1.2e-16 60.3 49.0 1.2e-16 60.3 34.0 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KFH43989.1 - 1.2e-05 23.7 23.4 2.2e-05 22.9 16.2 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) NTP_transferase PF00483.18 KFH43990.1 - 2.1e-29 102.5 0.0 3e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 KFH43990.1 - 1.2e-11 43.5 4.1 8.1e-05 21.9 0.0 3.7 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KFH43990.1 - 7.3e-07 29.4 0.0 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 KFH43990.1 - 0.039 13.4 0.0 0.091 12.2 0.0 1.5 2 0 0 2 2 2 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase FF PF01846.14 KFH43991.1 - 3e-12 46.3 6.6 2.2e-09 37.0 0.2 2.8 2 0 0 2 2 2 2 FF domain WW PF00397.21 KFH43991.1 - 9.7e-09 34.9 4.6 9.7e-09 34.9 3.2 2.0 2 0 0 2 2 2 1 WW domain Nuc_sug_transp PF04142.10 KFH43992.1 - 3e-79 265.5 0.9 4.1e-79 265.1 0.6 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 KFH43992.1 - 1e-10 41.4 21.5 2.4e-06 27.2 2.5 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 KFH43992.1 - 2.9e-09 36.2 4.3 1e-08 34.5 3.0 1.7 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KFH43992.1 - 3.9e-07 30.1 21.4 2.4e-06 27.6 2.1 3.1 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 KFH43992.1 - 0.00013 22.1 1.9 0.00013 22.1 1.3 2.7 2 1 0 2 2 2 1 Multidrug resistance efflux transporter DUF1479 PF07350.7 KFH43993.1 - 1.2e-146 488.5 0.0 1.9e-146 487.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) bZIP_1 PF00170.16 KFH43994.1 - 5e-05 23.1 13.5 0.00025 20.9 0.2 3.5 3 1 0 3 3 3 2 bZIP transcription factor ATG16 PF08614.6 KFH43994.1 - 0.00079 19.3 16.9 0.014 15.2 5.9 2.1 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) Myosin_tail_1 PF01576.14 KFH43994.1 - 0.0014 16.5 16.8 0.002 15.9 11.7 1.1 1 0 0 1 1 1 1 Myosin tail IncA PF04156.9 KFH43994.1 - 0.0092 15.6 21.7 0.021 14.4 14.7 1.7 1 1 0 1 1 1 1 IncA protein bZIP_2 PF07716.10 KFH43994.1 - 0.01 15.6 0.2 0.01 15.6 0.1 4.3 2 1 3 5 5 5 0 Basic region leucine zipper Reo_sigmaC PF04582.7 KFH43994.1 - 0.047 12.8 0.8 7.2 5.6 0.3 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 KFH43994.1 - 0.047 12.1 6.6 0.065 11.6 4.6 1.2 1 0 0 1 1 1 0 AAA domain DUF972 PF06156.8 KFH43994.1 - 0.048 14.0 0.7 0.048 14.0 0.5 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Alpha-2-MRAP_C PF06401.6 KFH43994.1 - 0.062 13.1 6.1 0.15 11.9 4.2 1.6 1 1 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain V_ATPase_I PF01496.14 KFH43994.1 - 0.076 10.8 8.4 0.12 10.2 5.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mnd1 PF03962.10 KFH43994.1 - 0.077 12.6 9.8 0.13 11.8 6.6 1.5 1 1 0 1 1 1 0 Mnd1 family Transposase_22 PF02994.9 KFH43994.1 - 0.1 11.0 6.9 0.21 10.0 4.8 1.5 1 1 0 1 1 1 0 L1 transposable element DUF1664 PF07889.7 KFH43994.1 - 0.15 11.8 3.2 0.26 11.1 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4559 PF15112.1 KFH43994.1 - 0.22 10.6 9.6 0.19 10.8 5.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) CENP-F_leu_zip PF10473.4 KFH43994.1 - 0.23 11.3 20.1 0.026 14.3 1.8 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.6 KFH43994.1 - 0.25 11.2 3.9 1.5 8.7 1.1 2.6 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) TPR_MLP1_2 PF07926.7 KFH43994.1 - 0.3 10.8 19.6 0.037 13.7 2.7 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.7 KFH43994.1 - 0.32 10.8 8.6 7.5 6.3 3.4 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ERM PF00769.14 KFH43994.1 - 0.93 8.9 17.0 0.79 9.2 11.0 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Spc7 PF08317.6 KFH43994.1 - 0.96 8.0 12.4 0.28 9.7 0.2 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Prominin PF05478.6 KFH43994.1 - 1 6.7 3.8 1.4 6.3 2.6 1.2 1 0 0 1 1 1 0 Prominin TMF_TATA_bd PF12325.3 KFH43994.1 - 1.2 8.8 20.3 2.5 7.8 5.8 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding TBPIP PF07106.8 KFH43994.1 - 1.3 8.5 13.3 9.9 5.6 4.7 2.5 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3080 PF11279.3 KFH43994.1 - 1.3 8.1 9.1 2 7.4 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) ADIP PF11559.3 KFH43994.1 - 1.3 8.8 18.9 0.6 9.9 0.6 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Kinesin-relat_1 PF12711.2 KFH43994.1 - 1.4 9.3 18.3 1.9 8.9 0.2 3.1 2 1 1 3 3 3 0 Kinesin motor Atg14 PF10186.4 KFH43994.1 - 1.6 7.6 13.9 4.4 6.1 9.7 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 MAD PF05557.8 KFH43994.1 - 1.9 6.4 17.8 0.06 11.4 5.8 1.9 1 1 1 2 2 2 0 Mitotic checkpoint protein Fib_alpha PF08702.5 KFH43994.1 - 2.4 8.2 6.2 3.8 7.6 1.6 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family HAUS-augmin3 PF14932.1 KFH43994.1 - 2.9 7.0 14.7 3.7 6.6 9.6 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 Scaffolding_pro PF11418.3 KFH43994.1 - 3.1 8.1 10.2 3.4 8.0 0.2 3.1 1 1 2 3 3 3 0 Phi29 scaffolding protein Macoilin PF09726.4 KFH43994.1 - 3.4 5.8 9.0 1.4 7.0 2.0 1.9 1 1 1 2 2 2 0 Transmembrane protein DUF1640 PF07798.6 KFH43994.1 - 4.5 7.2 9.3 17 5.4 6.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Laminin_II PF06009.7 KFH43994.1 - 6.2 6.5 7.1 7.4 6.3 3.6 2.0 1 1 1 2 2 2 0 Laminin Domain II Mod_r PF07200.8 KFH43994.1 - 6.5 6.6 15.6 6.9 6.5 4.1 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein APG6 PF04111.7 KFH43994.1 - 7.3 5.5 20.8 2.9 6.8 1.3 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 Phage_GPO PF05929.6 KFH43994.1 - 8.8 5.4 12.0 2.5 7.2 2.3 2.1 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Nup54 PF13874.1 KFH43994.1 - 9.8 5.8 16.9 1.1 8.9 3.5 2.6 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Dynamin_N PF00350.18 KFH43995.1 - 1.2e-21 77.2 0.0 7e-21 74.7 0.0 2.3 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KFH43995.1 - 1.2e-07 30.7 0.2 3e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region GED PF02212.13 KFH43995.1 - 4e-07 29.8 0.9 2.3e-06 27.4 0.0 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain Amidase02_C PF12123.3 KFH43995.1 - 0.037 13.6 0.0 0.11 12.1 0.0 1.9 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase ABC_tran PF00005.22 KFH43995.1 - 0.11 12.8 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter PAP2 PF01569.16 KFH43996.1 - 1e-21 76.9 0.5 1e-21 76.9 0.3 1.8 2 1 0 2 2 2 1 PAP2 superfamily Hira PF07569.6 KFH43997.1 - 3.3e-83 278.2 0.0 1.1e-82 276.5 0.0 1.9 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.27 KFH43997.1 - 8.7e-40 133.2 21.0 4.4e-07 29.5 0.1 8.6 8 0 0 8 8 8 7 WD domain, G-beta repeat HIRA_B PF09453.5 KFH43997.1 - 4.9e-09 35.4 0.5 1.5e-08 33.9 0.4 2.0 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 KFH43997.1 - 3.7e-05 23.2 0.2 12 5.7 0.0 5.2 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat IKI3 PF04762.7 KFH43997.1 - 0.082 10.7 0.0 0.79 7.4 0.0 2.3 3 0 0 3 3 3 0 IKI3 family NUDIX PF00293.23 KFH43998.1 - 9e-14 51.2 0.1 1.4e-13 50.6 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain Metallophos PF00149.23 KFH44000.1 - 2e-11 43.6 2.8 5.5e-11 42.2 1.9 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KFH44000.1 - 0.00037 20.3 0.1 0.001 18.9 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Cupin_5 PF06172.6 KFH44001.1 - 2.4e-41 140.9 0.0 2.8e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) polyprenyl_synt PF00348.12 KFH44002.1 - 2.7e-38 131.2 0.0 8.2e-38 129.7 0.0 1.7 2 0 0 2 2 2 1 Polyprenyl synthetase Transferase PF02458.10 KFH44003.1 - 1e-06 27.5 0.0 2.9e-06 26.0 0.0 1.6 1 1 0 1 1 1 1 Transferase family GPP34 PF05719.6 KFH44003.1 - 0.081 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) p450 PF00067.17 KFH44004.1 - 1.3e-16 60.1 0.4 1.3e-16 60.1 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 DnaJ PF00226.26 KFH44005.1 - 4e-13 48.8 0.7 4e-13 48.8 0.5 2.3 3 0 0 3 3 3 1 DnaJ domain Fungal_trans PF04082.13 KFH44006.1 - 4.2e-61 206.1 0.1 6e-61 205.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KFH44006.1 - 1.1e-07 31.7 13.1 0.00043 20.4 0.6 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFH44006.1 - 3.9e-07 29.9 7.5 0.0022 18.2 0.6 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFH44006.1 - 0.99 9.8 13.4 1.6 9.1 2.8 3.6 3 0 0 3 3 3 0 Zinc-finger double domain p450 PF00067.17 KFH44007.1 - 3.4e-06 25.8 0.0 5.4e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 HEAT_2 PF13646.1 KFH44008.1 - 4.9e-35 119.6 5.5 4.7e-17 62.0 0.1 3.9 2 2 2 4 4 4 4 HEAT repeats HEAT_PBS PF03130.11 KFH44008.1 - 2e-20 71.1 6.5 0.0019 18.5 0.1 6.7 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 KFH44008.1 - 1.8e-08 34.5 10.7 0.00016 22.0 0.1 5.3 3 2 2 5 5 5 2 HEAT-like repeat HEAT PF02985.17 KFH44008.1 - 9.5e-07 28.4 8.5 0.043 13.8 0.0 6.6 8 0 0 8 8 8 2 HEAT repeat Arm PF00514.18 KFH44008.1 - 0.0037 17.0 0.4 2.1 8.3 0.0 2.9 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat ParA PF10609.4 KFH44009.1 - 3.1e-33 113.4 0.0 5.9e-33 112.5 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KFH44009.1 - 8.7e-14 51.3 0.0 1.2e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KFH44009.1 - 3.8e-05 23.6 0.0 0.00012 22.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 KFH44009.1 - 0.0009 18.3 0.8 0.0037 16.3 0.2 2.0 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 KFH44009.1 - 0.0022 17.3 0.0 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain MipZ PF09140.6 KFH44009.1 - 0.0025 16.9 0.0 0.0086 15.1 0.0 1.8 1 1 0 1 1 1 1 ATPase MipZ DUF258 PF03193.11 KFH44009.1 - 0.014 14.6 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_26 PF13500.1 KFH44009.1 - 0.033 13.7 0.0 4.3 6.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KFH44009.1 - 0.067 13.3 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Fer4_NifH PF00142.13 KFH44009.1 - 0.12 11.5 0.0 0.95 8.5 0.0 2.0 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_19 PF13245.1 KFH44009.1 - 0.13 12.0 0.2 1.2 8.9 0.1 2.2 2 0 0 2 2 2 0 Part of AAA domain SRP54 PF00448.17 KFH44009.1 - 0.14 11.5 0.0 0.56 9.6 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_30 PF13604.1 KFH44009.1 - 0.16 11.5 0.0 0.34 10.4 0.0 1.5 2 0 0 2 2 2 0 AAA domain 4HBT PF03061.17 KFH44010.1 - 2.5e-11 43.5 0.0 3.5e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 KFH44010.1 - 0.00052 19.8 0.4 0.00076 19.2 0.1 1.4 1 1 0 1 1 1 1 Thioesterase-like superfamily 4HBT_2 PF13279.1 KFH44010.1 - 0.042 14.3 0.0 0.053 13.9 0.0 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily Cyt-b5 PF00173.23 KFH44011.1 - 2.7e-16 59.1 0.1 1.3e-15 56.8 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 KFH44011.1 - 1.4e-15 57.4 11.8 1.4e-15 57.4 8.2 1.6 1 1 1 2 2 2 1 Fatty acid desaturase TFIIB PF00382.14 KFH44012.1 - 0.00063 19.5 0.0 0.17 11.6 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat DUF3439 PF11921.3 KFH44013.1 - 0.04 13.6 2.8 0.063 13.0 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF605 PF04652.11 KFH44013.1 - 0.3 10.4 23.8 0.33 10.2 16.5 1.0 1 0 0 1 1 1 0 Vta1 like Vfa1 PF08432.5 KFH44013.1 - 1.5 8.7 14.8 3 7.8 3.0 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 PEX11 PF05648.9 KFH44013.1 - 2.9 7.0 4.3 0.72 9.0 0.9 1.4 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) ATP-synt_10 PF05176.9 KFH44013.1 - 4.3 6.5 9.8 0.42 9.8 1.5 2.0 2 0 0 2 2 2 0 ATP10 protein Totivirus_coat PF05518.6 KFH44013.1 - 8.1 4.1 7.9 11 3.7 5.5 1.1 1 0 0 1 1 1 0 Totivirus coat protein PC_rep PF01851.17 KFH44014.1 - 2.2e-17 62.2 18.9 1.7e-05 24.8 0.1 8.8 8 0 0 8 8 8 3 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KFH44014.1 - 4.5e-08 33.2 0.2 0.15 12.3 0.0 4.5 3 2 1 4 4 4 3 HEAT repeats Ras PF00071.17 KFH44016.1 - 1.4e-59 200.0 0.1 1.7e-59 199.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFH44016.1 - 1.5e-19 70.6 0.0 2.1e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFH44016.1 - 1.7e-09 37.1 0.0 1.9e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFH44016.1 - 3.7e-07 29.7 0.1 2.1e-06 27.3 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFH44016.1 - 0.00057 19.8 0.0 0.00082 19.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFH44016.1 - 0.0017 17.5 0.1 0.0024 17.0 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 KFH44016.1 - 0.018 14.2 0.0 0.036 13.3 0.0 1.5 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF258 PF03193.11 KFH44016.1 - 0.034 13.3 0.0 0.063 12.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 KFH44016.1 - 0.058 12.9 0.6 3 7.3 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein VGCC_beta4Aa_N PF12052.3 KFH44016.1 - 0.12 12.2 0.5 0.33 10.8 0.3 1.8 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal RRM_1 PF00076.17 KFH44017.1 - 7.5e-23 79.9 0.0 2.9e-11 42.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH44017.1 - 1.6e-13 50.4 0.0 4.8e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH44017.1 - 0.021 14.6 0.0 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2034 PF10356.4 KFH44018.1 - 2.9e-31 108.0 0.0 1.5e-17 63.3 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 KFH44018.1 - 8.2e-09 35.2 0.0 1.5e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease FAD_binding_1 PF00667.15 KFH44019.1 - 3.9e-61 206.2 0.0 6.4e-61 205.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KFH44019.1 - 1e-32 113.0 1.5 2.3e-32 111.9 1.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KFH44019.1 - 5.3e-22 78.4 0.0 5e-21 75.3 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KFH44019.1 - 0.036 14.0 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 Flavodoxin domain NTPase_I-T PF01931.13 KFH44020.1 - 8.8e-48 162.2 0.0 9.9e-48 162.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 F-box PF00646.28 KFH44022.1 - 5.3e-07 29.1 0.5 1.6e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KFH44022.1 - 2.2e-06 27.2 0.9 4e-06 26.4 0.1 1.9 2 0 0 2 2 2 1 F-box-like p450 PF00067.17 KFH44023.1 - 6.4e-68 229.3 0.0 8.6e-68 228.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MOR2-PAG1_N PF14222.1 KFH44024.1 - 1.5e-216 720.4 0.0 2.2e-216 719.8 0.0 1.3 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 KFH44024.1 - 3.7e-91 305.5 0.9 5.9e-91 304.8 0.0 1.9 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 KFH44024.1 - 2.8e-32 111.3 6.4 3e-12 45.0 0.1 3.3 2 1 1 3 3 3 3 Cell morphogenesis central region HEAT_2 PF13646.1 KFH44024.1 - 0.00023 21.3 0.0 1.7 9.0 0.0 5.8 5 1 1 6 6 6 1 HEAT repeats HEAT PF02985.17 KFH44024.1 - 0.011 15.7 3.9 2.9 8.2 0.0 5.3 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.1 KFH44024.1 - 0.21 12.0 1.8 1.9 9.0 0.0 3.6 3 0 0 3 3 3 0 HEAT-like repeat DUF3608 PF12257.3 KFH44025.1 - 3.3e-69 232.9 0.0 6.5e-69 231.9 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 KFH44025.1 - 2.7e-27 94.2 0.1 5.7e-27 93.2 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Mito_fiss_reg PF05308.6 KFH44025.1 - 0.068 12.5 12.9 0.22 10.8 8.9 1.8 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 KFH44025.1 - 4.1 6.5 11.6 10 5.3 8.1 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal p450 PF00067.17 KFH44026.1 - 1e-31 109.9 0.0 1.4e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FNIP_N PF14636.1 KFH44027.1 - 9.8e-28 97.2 0.4 9.8e-28 97.2 0.3 3.8 2 1 0 2 2 2 1 Folliculin-interacting protein N-terminus Nipped-B_C PF12830.2 KFH44028.1 - 3.7e-49 166.9 5.3 2.5e-47 160.9 0.1 3.4 4 0 0 4 4 4 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 KFH44028.1 - 3.7e-08 33.1 4.2 4.9e-08 32.7 0.8 2.8 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 KFH44028.1 - 5.2e-06 26.0 4.1 2.6 8.3 0.0 5.4 5 0 0 5 5 5 3 HEAT repeat Adaptin_N PF01602.15 KFH44028.1 - 0.00045 18.6 0.2 0.0082 14.5 0.1 2.7 3 0 0 3 3 3 1 Adaptin N terminal region HEAT_2 PF13646.1 KFH44028.1 - 0.0022 18.2 6.6 0.084 13.1 0.8 4.4 3 1 1 4 4 4 2 HEAT repeats TFIIS_C PF01096.13 KFH44029.1 - 6.4e-12 44.9 1.2 6.4e-12 44.9 0.8 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KFH44029.1 - 1.2e-06 28.0 5.4 2.1e-06 27.2 0.5 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit DZR PF12773.2 KFH44029.1 - 0.00035 20.3 3.7 0.038 13.8 0.5 2.4 2 0 0 2 2 2 2 Double zinc ribbon OrfB_Zn_ribbon PF07282.6 KFH44029.1 - 0.0051 16.4 9.6 0.04 13.5 2.0 2.4 2 1 0 2 2 2 2 Putative transposase DNA-binding domain zinc_ribbon_2 PF13240.1 KFH44029.1 - 0.0095 15.4 5.4 3.6 7.2 1.4 3.3 2 1 1 3 3 3 2 zinc-ribbon domain Cytochrom_c3_2 PF14537.1 KFH44029.1 - 0.016 15.5 1.9 0.025 14.9 1.3 1.3 1 0 0 1 1 1 0 Cytochrome c3 zf-ribbon_3 PF13248.1 KFH44029.1 - 0.016 14.4 4.5 3 7.1 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain NOB1_Zn_bind PF08772.6 KFH44029.1 - 0.016 15.0 5.1 1.5 8.6 0.4 3.2 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like ArfGap PF01412.13 KFH44029.1 - 0.022 14.5 4.1 0.35 10.6 0.1 2.1 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf C1_1 PF00130.17 KFH44029.1 - 0.067 12.9 6.0 0.076 12.7 0.2 2.4 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-CHY PF05495.7 KFH44029.1 - 0.069 13.3 4.4 3.7 7.7 0.5 2.3 2 0 0 2 2 2 0 CHY zinc finger Zn-ribbon_8 PF09723.5 KFH44029.1 - 0.098 12.6 5.5 4.3 7.3 0.9 2.7 2 1 0 2 2 2 0 Zinc ribbon domain IBR PF01485.16 KFH44029.1 - 0.14 12.0 0.2 0.14 12.0 0.2 3.0 2 1 0 2 2 2 0 IBR domain Zn_ribbon_recom PF13408.1 KFH44029.1 - 0.23 11.7 5.3 1.2 9.4 0.3 2.7 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain PADR1 PF08063.7 KFH44029.1 - 0.36 10.2 3.1 1.1 8.7 0.3 2.3 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-UBR PF02207.15 KFH44029.1 - 0.4 10.4 9.8 5 6.9 0.1 3.0 2 1 1 3 3 3 0 Putative zinc finger in N-recognin (UBR box) zf-MYND PF01753.13 KFH44029.1 - 0.47 10.3 4.3 5.8 6.8 0.7 2.3 2 0 0 2 2 2 0 MYND finger GFA PF04828.9 KFH44029.1 - 0.52 10.2 7.7 13 5.8 0.6 2.4 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme DUF1922 PF09082.5 KFH44029.1 - 0.75 9.9 6.9 13 5.9 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1922) TF_Zn_Ribbon PF08271.7 KFH44029.1 - 0.81 9.0 6.0 3.5 7.0 0.2 3.1 2 1 1 3 3 3 0 TFIIB zinc-binding A2L_zn_ribbon PF08792.5 KFH44029.1 - 0.86 9.1 11.3 3 7.3 0.1 3.9 4 0 0 4 4 4 0 A2L zinc ribbon domain zf-C2HC5 PF06221.8 KFH44029.1 - 0.89 9.3 6.1 3.4 7.5 0.4 2.9 3 0 0 3 3 3 0 Putative zinc finger motif, C2HC5-type zf-trcl PF13451.1 KFH44029.1 - 1.9 8.1 5.5 25 4.6 0.1 3.3 3 0 0 3 3 3 0 Probable zinc-binding domain Ribosomal_L37ae PF01780.14 KFH44029.1 - 2 8.3 4.8 1.8 8.5 0.5 2.1 1 1 1 2 2 2 0 Ribosomal L37ae protein family zf-HYPF PF07503.7 KFH44029.1 - 3.4 7.1 6.1 11 5.5 0.0 3.2 3 0 0 3 3 3 0 HypF finger zf-RING_4 PF14570.1 KFH44029.1 - 5.6 6.6 6.1 11 5.7 0.0 3.1 4 0 0 4 4 4 0 RING/Ubox like zinc-binding domain Nudix_N_2 PF14803.1 KFH44029.1 - 6.9 6.4 7.5 37 4.1 0.1 3.0 2 1 0 2 2 2 0 Nudix N-terminal FYVE PF01363.16 KFH44029.1 - 8.3 6.3 7.7 68 3.4 5.3 2.2 1 1 0 1 1 1 0 FYVE zinc finger p450 PF00067.17 KFH44030.1 - 1.2e-11 43.8 0.0 1.3e-11 43.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CTDII PF01556.13 KFH44031.1 - 4.1e-28 97.1 0.2 2e-21 75.6 0.0 3.2 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 KFH44031.1 - 3.1e-25 87.6 1.1 5.3e-25 86.9 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KFH44031.1 - 4.1e-11 42.7 20.6 7.9e-11 41.8 14.3 1.5 1 0 0 1 1 1 1 DnaJ central domain WSC PF01822.14 KFH44032.1 - 2.9e-10 39.9 9.3 2.9e-10 39.9 6.5 2.5 2 0 0 2 2 2 1 WSC domain Glyco_hydro_16 PF00722.16 KFH44032.1 - 4.3e-07 29.3 0.2 1.4e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Trypan_PARP PF05887.6 KFH44032.1 - 0.015 15.1 9.5 0.015 15.1 6.6 2.0 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) RIO1 PF01163.17 KFH44033.1 - 8.8e-42 142.5 0.1 3.5e-41 140.6 0.1 1.8 1 1 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 KFH44033.1 - 1.3e-32 111.6 0.0 2.8e-32 110.6 0.0 1.5 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 KFH44033.1 - 7.1e-07 29.1 0.0 0.0016 18.2 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KFH44033.1 - 3.6e-06 26.1 0.0 0.0047 16.0 0.0 2.5 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family DDHD PF02862.12 KFH44033.1 - 0.077 12.7 1.1 0.11 12.2 0.8 1.2 1 0 0 1 1 1 0 DDHD domain Daxx PF03344.10 KFH44033.1 - 0.16 10.4 23.7 0.21 10.0 16.4 1.1 1 0 0 1 1 1 0 Daxx Family CENP-T PF15511.1 KFH44033.1 - 0.33 10.1 16.9 0.46 9.6 11.7 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CDC45 PF02724.9 KFH44033.1 - 1.1 7.2 15.8 1.4 6.8 11.0 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.7 KFH44033.1 - 5.1 6.1 26.8 7.8 5.5 18.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Mpp10 PF04006.7 KFH44033.1 - 8.9 4.5 26.3 12 4.0 18.3 1.1 1 0 0 1 1 1 0 Mpp10 protein SAP30_Sin3_bdg PF13867.1 KFH44034.1 - 9e-14 51.0 1.0 3.7e-12 45.9 0.1 2.7 3 0 0 3 3 3 1 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF4286 PF14114.1 KFH44034.1 - 0.017 15.4 0.0 0.045 14.0 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4286) Xpo1 PF08389.7 KFH44036.1 - 2e-26 92.6 1.2 1.4e-25 89.9 0.2 3.1 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 KFH44036.1 - 7e-07 29.0 0.1 1.9e-06 27.6 0.1 1.8 1 0 0 1 1 1 1 Importin-beta N-terminal domain Adaptin_N PF01602.15 KFH44036.1 - 0.015 13.6 0.2 0.47 8.7 0.1 2.5 2 0 0 2 2 2 0 Adaptin N terminal region PI3Ka PF00613.15 KFH44036.1 - 0.048 12.8 0.1 0.92 8.6 0.0 2.3 2 0 0 2 2 2 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Pkinase PF00069.20 KFH44037.1 - 5.9e-11 42.0 0.0 6.4e-10 38.6 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH44037.1 - 3e-09 36.3 0.0 2.1e-08 33.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.27 KFH44038.1 - 3.5e-16 58.3 3.7 0.00011 21.9 0.0 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat Period_C PF12114.3 KFH44038.1 - 0.02 14.5 1.2 0.03 13.9 0.8 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Serglycin PF04360.7 KFH44038.1 - 0.053 13.2 1.8 0.1 12.3 1.3 1.4 1 0 0 1 1 1 0 Serglycin BNR PF02012.15 KFH44038.1 - 0.07 12.9 0.4 0.44 10.5 0.3 2.5 1 0 0 1 1 1 0 BNR/Asp-box repeat Pex2_Pex12 PF04757.9 KFH44039.1 - 7.8e-59 198.8 4.2 1e-58 198.4 2.9 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 KFH44039.1 - 9.8e-05 22.2 3.2 0.00017 21.5 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFH44039.1 - 0.0023 17.7 2.1 0.0036 17.0 1.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 KFH44039.1 - 0.0073 16.1 2.8 0.013 15.3 1.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KFH44039.1 - 0.2 11.3 2.1 0.37 10.5 1.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 KFH44039.1 - 0.94 9.5 4.9 0.49 10.4 0.2 2.3 2 0 0 2 2 2 0 zinc-finger GST_C PF00043.20 KFH44040.1 - 1.1e-12 47.7 0.1 2.2e-12 46.8 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KFH44040.1 - 1.7e-12 47.4 0.0 6.3e-12 45.5 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFH44040.1 - 6.7e-11 42.0 0.0 1.3e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFH44040.1 - 8.2e-11 41.6 0.0 2.2e-10 40.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KFH44040.1 - 1.7e-09 37.6 0.0 6.4e-07 29.4 0.0 2.7 3 0 0 3 3 3 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KFH44040.1 - 1.1e-07 32.1 0.1 1.7e-07 31.6 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain OPT PF03169.10 KFH44041.1 - 2.5e-207 690.1 35.9 2.9e-207 689.9 24.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TFIIA PF03153.8 KFH44041.1 - 1.6 8.5 14.5 2.5 7.9 10.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit 5-FTHF_cyc-lig PF01812.15 KFH44042.1 - 3.1e-29 102.0 0.0 4e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Lon_C PF05362.8 KFH44043.1 - 7.2e-64 214.8 0.0 1.4e-63 213.9 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 KFH44043.1 - 5.7e-35 120.8 0.2 1.6e-34 119.3 0.1 1.8 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 KFH44043.1 - 2.2e-21 76.4 0.0 5.8e-21 75.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 KFH44043.1 - 4e-08 32.7 0.0 9.4e-08 31.6 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 KFH44043.1 - 1.2e-06 28.3 0.0 3.8e-06 26.6 0.0 1.9 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KFH44043.1 - 2.4e-06 27.5 0.0 9.3e-06 25.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KFH44043.1 - 5.1e-05 23.4 0.0 0.001 19.2 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 KFH44043.1 - 5.2e-05 22.1 0.0 0.0001 21.1 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_17 PF13207.1 KFH44043.1 - 6.8e-05 23.6 0.0 0.00031 21.5 0.0 2.2 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KFH44043.1 - 0.00021 20.4 0.0 0.0012 18.0 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KFH44043.1 - 0.00027 20.9 0.3 0.0039 17.1 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 KFH44043.1 - 0.012 15.5 0.0 0.033 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain ClpB_D2-small PF10431.4 KFH44043.1 - 0.021 14.7 0.4 0.021 14.7 0.3 3.1 3 0 0 3 3 3 0 C-terminal, D2-small domain, of ClpB protein MobB PF03205.9 KFH44043.1 - 0.023 14.4 0.0 0.067 12.8 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 KFH44043.1 - 0.027 13.9 0.0 0.066 12.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 KFH44043.1 - 0.028 14.5 0.0 0.088 12.9 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 KFH44043.1 - 0.029 14.6 0.0 0.029 14.6 0.0 2.6 3 0 0 3 3 2 0 AAA domain DUF258 PF03193.11 KFH44043.1 - 0.042 13.0 0.0 0.095 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 KFH44043.1 - 0.075 12.4 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFH44043.1 - 0.093 12.6 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KFH44043.1 - 0.59 10.4 5.6 0.73 10.1 0.0 3.0 3 0 0 3 3 3 0 ABC transporter MoCF_biosynth PF00994.19 KFH44044.1 - 1.2e-34 118.8 0.0 1.9e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain ANF_receptor PF01094.23 KFH44044.1 - 0.093 11.5 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 Receptor family ligand binding region DIM1 PF02966.11 KFH44045.1 - 1.1e-69 232.0 0.1 1.3e-69 231.8 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 KFH44045.1 - 0.00094 18.8 0.0 0.0012 18.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KFH44045.1 - 0.0013 18.8 0.5 0.002 18.1 0.3 1.4 1 1 0 1 1 1 1 Thioredoxin-like DEAD PF00270.24 KFH44046.1 - 2.4e-44 150.7 0.0 1.3e-43 148.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFH44046.1 - 1.4e-22 79.3 0.1 1.2e-21 76.3 0.1 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 KFH44046.1 - 1.3e-18 66.4 1.9 3.7e-18 65.0 1.3 1.8 1 0 0 1 1 1 1 DBP10CT (NUC160) domain DNA_pol_phi PF04931.8 KFH44046.1 - 6.8 4.3 11.4 13 3.3 7.9 1.3 1 0 0 1 1 1 0 DNA polymerase phi AMP-binding PF00501.23 KFH44047.1 - 8.8e-78 261.5 0.0 1.5e-77 260.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme KR PF08659.5 KFH44047.1 - 3.5e-48 163.6 1.8 3.4e-47 160.4 0.0 2.9 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.16 KFH44047.1 - 4.9e-45 154.2 0.0 8.9e-45 153.3 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Condensation PF00668.15 KFH44047.1 - 7.6e-43 146.4 0.0 1.2e-42 145.8 0.0 1.3 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.1 KFH44047.1 - 1.7e-42 145.5 0.1 3.7e-42 144.4 0.1 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KFH44047.1 - 2.6e-42 144.5 2.7 1.7e-40 138.6 0.0 3.7 3 0 0 3 3 3 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KFH44047.1 - 1.5e-38 132.1 0.0 2.6e-38 131.3 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KFH44047.1 - 1.8e-21 76.6 0.0 1.5e-17 63.8 0.0 2.6 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KFH44047.1 - 5.7e-21 74.5 0.1 5.8e-11 42.4 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 KFH44047.1 - 3.1e-15 56.2 0.0 8e-15 54.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH44047.1 - 1.7e-14 54.0 0.0 1e-13 51.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH44047.1 - 2.4e-11 43.9 0.0 1.8e-10 41.1 0.0 2.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH44047.1 - 9.5e-10 38.2 0.0 2.8e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.14 KFH44047.1 - 4.9e-08 32.0 0.0 2.2e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family HxxPF_rpt PF13745.1 KFH44047.1 - 7.4e-08 32.5 0.0 4.3e-07 30.1 0.0 2.4 2 0 0 2 2 1 1 HxxPF-repeated domain Methyltransf_18 PF12847.2 KFH44047.1 - 1.5e-06 28.7 0.0 9.3e-06 26.1 0.0 2.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFH44047.1 - 2.1e-06 27.7 0.1 2.1e-05 24.5 0.0 2.9 2 0 0 2 2 1 1 Methyltransferase domain PCMT PF01135.14 KFH44047.1 - 0.085 12.3 0.0 0.43 10.0 0.0 2.2 3 0 0 3 3 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NmrA PF05368.8 KFH44047.1 - 0.16 11.2 0.0 3.4 6.8 0.0 2.3 2 0 0 2 2 2 0 NmrA-like family Methyltransf_16 PF10294.4 KFH44047.1 - 0.45 9.9 0.0 0.94 8.9 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase p450 PF00067.17 KFH44048.1 - 2.1e-24 85.9 0.0 2.8e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KFH44049.1 - 4.7e-39 134.0 25.9 4.7e-39 134.0 17.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily zf-CCCH PF00642.19 KFH44051.1 - 1.8e-08 33.8 13.6 1.1e-05 24.9 0.4 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KFH44051.1 - 10 6.3 15.6 0.19 11.8 2.9 3.5 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type DUF4406 PF14359.1 KFH44052.1 - 0.035 14.1 0.0 0.24 11.5 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4406) TMF_TATA_bd PF12325.3 KFH44052.1 - 0.38 10.4 3.9 0.24 11.1 0.7 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding PRKCSH-like PF12999.2 KFH44053.1 - 2.2e-39 134.8 14.0 1.9e-23 82.9 0.3 3.8 5 0 0 5 5 5 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 KFH44053.1 - 4.1e-32 110.7 2.3 4.7e-32 110.6 0.4 1.9 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 KFH44053.1 - 8.7e-12 45.6 1.1 3.8e-11 43.6 0.8 2.2 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein DUF4407 PF14362.1 KFH44053.1 - 0.015 14.2 7.4 0.14 11.0 3.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FlxA PF14282.1 KFH44053.1 - 0.032 14.1 1.9 0.58 10.1 0.1 2.7 3 0 0 3 3 3 0 FlxA-like protein DFF-C PF09033.5 KFH44053.1 - 0.04 13.7 1.2 0.055 13.3 0.0 1.8 2 0 0 2 2 2 0 DNA Fragmentation factor 45kDa, C terminal domain Mig-14 PF07395.6 KFH44053.1 - 0.042 12.8 1.3 0.078 11.9 0.9 1.4 1 0 0 1 1 1 0 Mig-14 CASP_C PF08172.7 KFH44053.1 - 0.063 12.2 8.1 0.092 11.7 2.9 2.1 2 0 0 2 2 2 0 CASP C terminal Snapin_Pallidin PF14712.1 KFH44053.1 - 0.14 12.4 0.0 0.14 12.4 0.0 2.7 3 0 0 3 3 3 0 Snapin/Pallidin OmpH PF03938.9 KFH44053.1 - 0.32 10.9 7.3 7 6.5 2.7 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) TPR_MLP1_2 PF07926.7 KFH44053.1 - 0.36 10.5 15.5 7.2 6.3 6.4 3.1 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF3086 PF11285.3 KFH44053.1 - 0.46 9.2 6.9 0.32 9.7 0.0 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF3086) Striatin PF08232.7 KFH44053.1 - 0.77 10.0 15.0 0.8 10.0 0.1 3.3 3 1 0 3 3 3 0 Striatin family DivIC PF04977.10 KFH44053.1 - 1.2 8.6 14.1 2.9 7.4 0.1 3.6 3 1 0 3 3 3 0 Septum formation initiator Dppa2_A PF14049.1 KFH44053.1 - 2.8 7.8 7.9 2.1 8.2 0.2 2.6 1 1 1 2 2 2 0 Dppa2/4 conserved region in higher vertebrates IncA PF04156.9 KFH44053.1 - 4.4 6.8 16.1 25 4.3 0.6 3.2 2 1 1 3 3 3 0 IncA protein GAS PF13851.1 KFH44053.1 - 6 6.0 18.7 5.4 6.1 6.2 3.0 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding adh_short_C2 PF13561.1 KFH44055.1 - 1.3e-18 67.6 0.4 1.1e-09 38.4 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFH44055.1 - 9.5e-15 54.8 3.8 1.7e-14 54.0 2.6 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH44055.1 - 1.4e-08 34.5 5.0 2.5e-08 33.8 3.2 1.7 1 1 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 KFH44055.1 - 2.1e-05 23.6 0.6 3.4e-05 23.0 0.4 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3HCDH_N PF02737.13 KFH44055.1 - 0.00015 21.4 1.6 0.00015 21.4 1.1 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KFH44055.1 - 0.00055 20.3 0.7 0.0012 19.2 0.5 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 KFH44055.1 - 0.00085 18.0 0.2 0.0012 17.6 0.2 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_25 PF13649.1 KFH44055.1 - 0.0024 18.1 0.0 0.0046 17.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_4 PF07993.7 KFH44055.1 - 0.0031 16.4 0.0 0.004 16.1 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein TrkA_N PF02254.13 KFH44055.1 - 0.0059 16.6 0.3 0.018 15.0 0.1 2.0 1 1 1 2 2 2 1 TrkA-N domain Shikimate_DH PF01488.15 KFH44055.1 - 0.01 15.9 0.2 0.018 15.1 0.2 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase B12-binding PF02310.14 KFH44055.1 - 0.02 14.7 0.5 0.048 13.5 0.3 1.7 1 1 0 1 1 1 0 B12 binding domain NAD_binding_2 PF03446.10 KFH44055.1 - 0.023 14.5 0.1 0.052 13.3 0.1 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 KFH44055.1 - 0.091 12.4 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Zn_clus PF00172.13 KFH44056.1 - 4.6e-07 29.6 10.4 7.8e-07 28.8 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_7 PF00840.15 KFH44057.1 - 5e-181 601.8 8.5 6e-181 601.5 5.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Yip1 PF04893.12 KFH44058.1 - 4.2e-05 23.1 18.7 0.00081 18.9 12.9 2.3 1 1 0 1 1 1 1 Yip1 domain MFS_1 PF07690.11 KFH44059.1 - 3.3e-35 121.4 24.2 1.6e-34 119.1 17.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Cupin_2 PF07883.6 KFH44060.1 - 2.4e-14 52.6 0.2 5.3e-14 51.4 0.0 1.6 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.7 KFH44060.1 - 8.7e-07 28.2 0.0 1.2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_6 PF12852.2 KFH44060.1 - 2.8e-05 23.8 0.0 3.2e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_1 PF00190.17 KFH44060.1 - 0.002 17.5 0.0 0.0031 16.9 0.0 1.3 1 1 0 1 1 1 1 Cupin 3-HAO PF06052.7 KFH44060.1 - 0.0048 16.3 0.0 0.0053 16.1 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase HgmA PF04209.8 KFH44060.1 - 0.017 13.4 0.0 0.019 13.3 0.0 1.1 1 0 0 1 1 1 0 homogentisate 1,2-dioxygenase cNMP_binding PF00027.24 KFH44060.1 - 0.023 14.5 0.0 0.044 13.6 0.0 1.5 1 1 0 1 1 1 0 Cyclic nucleotide-binding domain EutQ PF06249.7 KFH44060.1 - 0.034 13.6 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ AraC_binding PF02311.14 KFH44060.1 - 0.082 12.5 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 AraC-like ligand binding domain FAD_binding_3 PF01494.14 KFH44061.1 - 1.9e-16 60.0 0.6 1.4e-15 57.2 0.4 2.2 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KFH44061.1 - 6.5e-09 35.6 0.8 1.6e-08 34.4 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFH44061.1 - 7.7e-08 31.6 4.3 6.8e-07 28.5 2.0 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KFH44061.1 - 3.2e-05 23.1 0.0 0.0048 16.0 0.1 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 KFH44061.1 - 6.9e-05 23.1 1.9 7.7e-05 23.0 0.3 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFH44061.1 - 7.9e-05 22.6 0.0 0.00019 21.3 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFH44061.1 - 0.00033 19.6 2.1 0.0017 17.2 1.1 2.0 1 1 1 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 KFH44061.1 - 0.0015 17.6 0.1 0.0025 16.9 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KFH44061.1 - 0.0021 17.0 0.1 0.0033 16.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 KFH44061.1 - 0.037 12.8 1.3 0.059 12.2 0.9 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KFH44061.1 - 0.041 13.9 1.6 0.083 12.9 1.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KFH44061.1 - 0.096 12.3 1.5 0.18 11.4 1.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF815 PF05673.8 KFH44061.1 - 0.099 11.5 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NAD_Gly3P_dh_N PF01210.18 KFH44061.1 - 0.12 12.1 0.4 0.22 11.2 0.2 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Rossmann-like PF10727.4 KFH44061.1 - 0.12 12.1 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 Rossmann-like domain ApbA PF02558.11 KFH44061.1 - 0.41 10.0 2.7 0.57 9.6 0.5 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 KFH44061.1 - 0.44 8.9 1.8 0.75 8.1 1.3 1.3 1 0 0 1 1 1 0 HI0933-like protein NABP PF07990.7 KFH44062.1 - 0.13 11.4 3.1 0.15 11.3 2.1 1.0 1 0 0 1 1 1 0 Nucleic acid binding protein NABP VSG_B PF13206.1 KFH44062.1 - 0.35 9.9 3.7 0.4 9.7 2.6 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain Med15 PF09606.5 KFH44062.1 - 0.64 8.1 13.7 0.7 8.0 9.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 KFH44062.1 - 1.5 6.9 14.0 1.6 6.8 9.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PHD_3 PF13922.1 KFH44062.1 - 4.1 7.7 6.0 2.6 8.3 2.4 1.8 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx PAP_assoc PF03828.14 KFH44063.1 - 4.1e-11 42.6 0.1 7.7e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KFH44063.1 - 1.1e-07 32.0 0.0 2.5e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain p450 PF00067.17 KFH44065.1 - 2.5e-70 237.2 0.0 3e-70 237.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GFO_IDH_MocA PF01408.17 KFH44066.1 - 3.8e-26 91.9 0.0 5.8e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KFH44066.1 - 5.7e-14 51.8 0.0 9.6e-14 51.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 KFH44066.1 - 6.2e-05 23.3 0.1 0.00011 22.5 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 KFH44066.1 - 0.016 15.5 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 KFH44066.1 - 0.022 13.7 0.1 0.033 13.1 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Trp_DMAT PF11991.3 KFH44067.1 - 4.9e-84 282.6 0.0 7e-84 282.1 0.0 1.2 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase p450 PF00067.17 KFH44067.1 - 5.6e-27 94.3 0.0 8.8e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF1674 PF07896.7 KFH44068.1 - 0.052 13.7 1.1 0.4 10.9 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1674) ketoacyl-synt PF00109.21 KFH44069.1 - 2.2e-52 178.0 0.0 2.9e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Cation_efflux PF01545.16 KFH44069.1 - 0.089 11.8 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Cation efflux family NmrA PF05368.8 KFH44070.1 - 3.6e-16 59.1 0.0 5.1e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFH44070.1 - 7.9e-14 52.0 0.0 1.2e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KFH44070.1 - 1.1e-09 37.8 0.0 1.4e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 KFH44070.1 - 0.00012 21.1 0.1 0.0029 16.5 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.16 KFH44070.1 - 0.00014 21.3 0.0 0.00021 20.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KFH44070.1 - 0.00023 21.4 0.2 0.0013 19.0 0.1 2.1 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KFH44070.1 - 0.0047 16.8 0.0 0.0098 15.8 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.13 KFH44070.1 - 0.0051 16.7 0.0 0.0089 16.0 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.20 KFH44070.1 - 0.0068 16.3 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase F420_oxidored PF03807.12 KFH44070.1 - 0.0071 16.7 0.2 0.022 15.1 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.5 KFH44070.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.14 KFH44070.1 - 0.015 14.0 0.0 0.024 13.3 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_kinase PF01513.16 KFH44071.1 - 5e-43 146.9 0.0 1.9e-42 144.9 0.0 1.6 1 1 0 1 1 1 1 ATP-NAD kinase MFS_1 PF07690.11 KFH44072.1 - 4.6e-22 78.2 26.2 6.1e-22 77.8 18.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily CoA_transf_3 PF02515.12 KFH44073.1 - 3.7e-28 98.0 0.1 1.1e-27 96.5 0.0 1.7 2 0 0 2 2 2 1 CoA-transferase family III KR PF08659.5 KFH44074.1 - 1.5e-52 177.8 0.0 4.5e-52 176.3 0.0 1.9 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 KFH44074.1 - 4.4e-45 154.4 0.0 3.4e-44 151.4 0.0 2.4 1 1 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 KFH44074.1 - 9.6e-41 139.4 0.1 5.9e-40 136.9 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 KFH44074.1 - 1.3e-33 116.4 0.0 2.3e-33 115.6 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KFH44074.1 - 1.7e-33 114.9 0.0 3.7e-33 113.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KFH44074.1 - 2e-16 60.2 0.0 5.3e-16 58.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH44074.1 - 3.3e-13 49.6 0.0 1.1e-12 47.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain ketoacyl-synt PF00109.21 KFH44074.1 - 2.7e-11 43.4 0.0 5.7e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Methyltransf_31 PF13847.1 KFH44074.1 - 1.3e-08 34.5 0.0 3.2e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH44074.1 - 9.5e-08 32.4 0.0 3.3e-07 30.7 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH44074.1 - 1e-07 32.4 0.0 2.5e-06 28.0 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 KFH44074.1 - 1.2e-05 25.5 0.0 2.8e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.13 KFH44074.1 - 7.4e-05 21.9 0.0 0.00015 20.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KFH44074.1 - 0.0036 17.6 0.0 0.011 16.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Acyltransferase PF01553.16 KFH44075.1 - 3.6e-29 100.8 0.0 5.4e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase ESPR PF13018.1 KFH44075.1 - 0.024 14.2 1.7 0.054 13.1 1.2 1.6 1 0 0 1 1 1 0 Extended Signal Peptide of Type V secretion system F-box-like PF12937.2 KFH44076.1 - 0.18 11.5 3.0 0.19 11.4 0.0 2.6 3 0 0 3 3 3 0 F-box-like UFD1 PF03152.9 KFH44077.1 - 1.4e-23 82.9 0.0 7.5e-19 67.5 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 zf-C2H2_4 PF13894.1 KFH44077.1 - 0.2 12.0 13.4 0.64 10.4 0.4 4.2 3 0 0 3 3 3 0 C2H2-type zinc finger TF_Zn_Ribbon PF08271.7 KFH44077.1 - 0.21 10.9 0.1 0.21 10.9 0.1 2.6 4 0 0 4 4 4 0 TFIIB zinc-binding NblA PF04485.7 KFH44077.1 - 0.4 10.5 1.0 6.3 6.7 0.1 2.7 3 0 0 3 3 3 0 Phycobilisome degradation protein nblA DUF3505 PF12013.3 KFH44077.1 - 3.3 8.0 10.8 6.4 7.0 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3505) RCC1 PF00415.13 KFH44078.1 - 9.8e-61 201.7 11.2 1.8e-11 44.0 0.1 7.6 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KFH44078.1 - 1.3e-38 129.7 29.2 3.5e-11 42.3 0.3 7.0 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 KFH44078.1 - 0.065 12.7 0.8 6 6.4 0.0 2.6 2 0 0 2 2 2 0 Putative carbohydrate binding domain MFS_1 PF07690.11 KFH44080.1 - 2e-35 122.1 30.8 2.6e-35 121.7 21.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily GCIP PF13324.1 KFH44081.1 - 3.8e-06 26.3 0.8 7.7e-06 25.3 0.2 1.7 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting DUF4484 PF14831.1 KFH44081.1 - 0.04 14.0 0.6 0.07 13.2 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) DUF1470 PF07336.6 KFH44081.1 - 3.4 8.0 7.7 0.24 11.7 0.9 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1470) Dioxygenase_C PF00775.16 KFH44082.1 - 4.8e-46 156.3 0.0 1.1e-33 116.0 0.0 2.1 2 0 0 2 2 2 2 Dioxygenase Dioxygenase_N PF04444.9 KFH44082.1 - 9.3e-11 41.5 0.0 1.9e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 KFH44082.1 - 6.9e-05 22.8 0.0 0.048 13.7 0.0 2.5 2 0 0 2 2 2 2 Carboxypeptidase regulatory-like domain DUF2824 PF11039.3 KFH44082.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2824) Colipase-like PF15083.1 KFH44083.1 - 0.02 14.8 4.8 0.92 9.4 0.5 2.2 2 0 0 2 2 2 0 Colipase-like WAP PF00095.16 KFH44083.1 - 2.2 8.3 14.0 3.9 7.5 1.4 2.6 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Gamma-thionin PF00304.15 KFH44083.1 - 2.3 8.2 12.8 3.4 7.7 2.1 2.4 2 0 0 2 2 2 0 Gamma-thionin family Colipase PF01114.13 KFH44083.1 - 5.6 6.5 14.5 5.4 6.5 1.2 2.4 2 0 0 2 2 2 0 Colipase, N-terminal domain ACI44 PF15270.1 KFH44083.1 - 6.1 6.9 9.1 8.2 6.4 0.7 2.3 2 0 0 2 2 2 0 Metallo-carboxypeptidase inhibitor Squash PF00299.13 KFH44083.1 - 6.3 6.7 11.9 5.8 6.8 1.6 2.4 2 0 0 2 2 2 0 Squash family serine protease inhibitor 5_nucleotid_C PF02872.13 KFH44086.1 - 7.2e-35 120.2 0.1 1.2e-34 119.5 0.1 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 KFH44086.1 - 8.3e-14 51.4 1.6 2.9e-13 49.6 1.4 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase PGA_cap PF09587.5 KFH44086.1 - 0.0028 17.0 0.0 0.0065 15.8 0.0 1.7 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap YmdB PF13277.1 KFH44086.1 - 0.0055 15.7 0.0 0.0097 14.9 0.0 1.3 1 0 0 1 1 1 1 YmdB-like protein zf-C3HC4_3 PF13920.1 KFH44087.1 - 1.4 8.6 7.1 4.5 7.0 4.9 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) EthD PF07110.6 KFH44088.1 - 7.4e-15 55.6 0.0 9.3e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 EthD domain Ribonuc_L-PSP PF01042.16 KFH44089.1 - 1.4e-15 57.1 0.0 1.5e-14 53.8 0.0 1.9 1 1 0 1 1 1 1 Endoribonuclease L-PSP polyprenyl_synt PF00348.12 KFH44090.1 - 1.4e-14 53.5 0.3 3.2e-14 52.4 0.2 1.5 1 1 0 1 1 1 1 Polyprenyl synthetase DNA_pol3_a_NII PF11490.3 KFH44090.1 - 0.074 12.6 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II PLA2_B PF01735.13 KFH44091.1 - 2.5e-182 606.4 0.5 3e-182 606.2 0.3 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain SnoaL_4 PF13577.1 KFH44092.1 - 0.0023 17.8 0.0 0.0024 17.7 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Abhydrolase_6 PF12697.2 KFH44093.1 - 2.6e-26 92.8 0.0 3.3e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH44093.1 - 1.6e-17 63.5 0.1 4.7e-17 62.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KFH44093.1 - 3.1e-06 26.9 0.0 5.5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 KFH44093.1 - 4.6e-06 26.3 0.0 8.7e-05 22.1 0.0 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KFH44093.1 - 0.00023 20.6 0.0 0.055 12.9 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase PAF-AH_p_II PF03403.8 KFH44093.1 - 0.0019 16.5 1.4 0.021 13.1 0.1 2.2 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II PGAP1 PF07819.8 KFH44093.1 - 0.0037 16.8 0.2 0.015 14.9 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein Ser_hydrolase PF06821.8 KFH44093.1 - 0.04 13.5 0.0 0.24 10.9 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase Lipase PF00151.14 KFH44093.1 - 0.056 12.6 0.0 0.082 12.1 0.0 1.2 1 0 0 1 1 1 0 Lipase DUF1057 PF06342.7 KFH44093.1 - 0.061 12.1 0.0 0.082 11.7 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) CFEM PF05730.6 KFH44094.1 - 4e-14 52.1 8.5 5.4e-14 51.7 5.9 1.2 1 0 0 1 1 1 1 CFEM domain PT PF04886.7 KFH44094.1 - 0.00016 20.9 24.5 0.00016 20.9 17.0 2.7 1 1 1 2 2 2 1 PT repeat Trypan_PARP PF05887.6 KFH44094.1 - 0.17 11.6 16.5 0.25 11.1 11.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MCPVI PF02993.9 KFH44094.1 - 0.32 11.1 1.4 0.4 10.8 1.0 1.1 1 0 0 1 1 1 0 Minor capsid protein VI FAD_binding_3 PF01494.14 KFH44095.1 - 2.1e-12 46.7 0.0 4.3e-07 29.3 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain PulS_OutS PF09691.5 KFH44095.1 - 0.12 12.4 0.2 0.39 10.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial chaperone lipoprotein (PulS_OutS) ketoacyl-synt PF00109.21 KFH44096.1 - 2.9e-79 266.1 0.0 5.5e-79 265.2 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KFH44096.1 - 4e-31 107.3 0.0 1.6e-30 105.3 0.0 2.0 1 1 1 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 KFH44096.1 - 4.7e-05 22.4 0.0 8.7e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 KFH44096.1 - 0.048 13.3 1.2 0.18 11.4 0.5 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Astro_capsid PF03115.9 KFH44097.1 - 3.9 5.6 8.8 4.7 5.3 6.1 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Fmp27 PF10344.4 KFH44097.1 - 4.4 4.8 9.4 6.3 4.3 6.5 1.3 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 AHS1 PF02682.11 KFH44097.1 - 7.1 6.0 11.2 11 5.3 7.8 1.3 1 0 0 1 1 1 0 Allophanate hydrolase subunit 1 p450 PF00067.17 KFH44098.1 - 2.2e-37 128.6 0.0 3.2e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 KFH44098.1 - 2.1e-14 53.3 0.1 1.1e-13 51.0 0.0 1.9 1 1 1 2 2 2 1 FAD binding domain FBPase_glpX PF03320.8 KFH44098.1 - 0.26 9.9 0.6 0.44 9.1 0.4 1.3 1 0 0 1 1 1 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded Amidohydro_2 PF04909.9 KFH44099.1 - 2.5e-42 145.3 0.2 3.1e-42 145.0 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase FtsJ PF01728.14 KFH44101.1 - 8e-60 201.9 0.0 1e-59 201.5 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase MFS_1 PF07690.11 KFH44102.1 - 4.3e-32 111.1 23.3 4.3e-32 111.1 16.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily FSH1 PF03959.8 KFH44103.1 - 3.7e-21 75.5 0.0 4.3e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KFH44103.1 - 0.081 12.6 0.0 0.098 12.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family FBPase PF00316.15 KFH44104.1 - 8.2e-122 406.0 0.0 9.4e-122 405.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase CIA30 PF08547.7 KFH44105.1 - 2.2e-25 89.3 0.0 3e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Polyketide_cyc2 PF10604.4 KFH44105.1 - 0.064 13.4 0.5 0.11 12.6 0.2 1.7 1 1 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport Amidohydro_2 PF04909.9 KFH44107.1 - 9.6e-17 61.4 0.0 1e-16 61.3 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase UDP-g_GGTase PF06427.6 KFH44107.1 - 0.1 11.8 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 UDP-glucose:Glycoprotein Glucosyltransferase Caps_synth PF05704.7 KFH44108.1 - 3.9e-13 49.2 0.0 6.7e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Methyltransf_31 PF13847.1 KFH44108.1 - 4e-06 26.4 0.0 8.4e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Gly_transf_sug PF04488.10 KFH44108.1 - 1e-05 25.8 0.0 2.6e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Methyltransf_23 PF13489.1 KFH44108.1 - 5.1e-05 23.0 0.0 9.5e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH44108.1 - 0.0002 21.9 0.0 0.00055 20.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFH44108.1 - 0.059 13.7 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 KFH44108.1 - 0.12 11.4 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF3425 PF11905.3 KFH44109.1 - 2.5e-22 79.2 0.2 4.5e-22 78.4 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) SP2 PF03014.9 KFH44109.1 - 0.42 8.4 5.4 0.58 7.9 3.7 1.1 1 0 0 1 1 1 0 Structural protein 2 TFIIA PF03153.8 KFH44109.1 - 4.7 7.0 9.9 6.1 6.6 6.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glyco_hydro_16 PF00722.16 KFH44110.1 - 3.2e-41 140.6 2.5 5.1e-41 140.0 1.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Sporozoite_P67 PF05642.6 KFH44110.1 - 0.28 8.9 12.4 0.43 8.3 8.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.7 KFH44110.1 - 3.4 5.4 12.3 4.5 5.0 8.5 1.0 1 0 0 1 1 1 0 Nop14-like family GST_N_3 PF13417.1 KFH44111.1 - 1.3e-18 67.0 0.0 2.2e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFH44111.1 - 9.3e-14 51.1 0.0 1.6e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KFH44111.1 - 5.4e-11 42.5 0.0 9.2e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFH44111.1 - 0.00027 20.7 0.1 0.00056 19.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 KFH44111.1 - 0.00081 19.3 0.0 0.002 18.1 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin SIR2 PF02146.12 KFH44112.1 - 4.8e-36 124.1 0.0 9.2e-36 123.2 0.0 1.4 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 KFH44112.1 - 0.015 15.0 0.1 0.16 11.6 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Zn-ribbon_8 PF09723.5 KFH44112.1 - 0.025 14.5 0.1 0.025 14.5 0.1 1.7 2 0 0 2 2 2 0 Zinc ribbon domain Peripla_BP_4 PF13407.1 KFH44112.1 - 0.032 13.5 0.1 0.047 13.0 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein domain CHASE2 PF05226.6 KFH44112.1 - 0.096 11.9 0.0 0.45 9.6 0.0 1.9 2 0 0 2 2 2 0 CHASE2 domain zf-ribbon_3 PF13248.1 KFH44112.1 - 1.3 8.3 5.5 11 5.3 0.0 2.8 3 0 0 3 3 3 0 zinc-ribbon domain DUF946 PF06101.6 KFH44113.1 - 1.4e-09 36.5 0.3 2e-09 36.0 0.2 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) Cytochrom_B_N PF00033.14 KFH44114.1 - 0.17 11.2 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB DUF3040 PF11239.3 KFH44114.1 - 0.18 11.8 0.1 0.44 10.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Glyco_hydro_43 PF04616.9 KFH44115.1 - 5.7e-36 124.0 5.4 6.5e-36 123.8 3.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Fungal_trans PF04082.13 KFH44116.1 - 1.6e-22 79.6 0.0 3.4e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rcd1 PF04078.8 KFH44118.1 - 6.1e-113 376.0 3.8 6.8e-113 375.8 2.6 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like PEX11 PF05648.9 KFH44119.1 - 2.2e-72 242.9 0.9 2.4e-72 242.8 0.6 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Pec_lyase_C PF00544.14 KFH44120.1 - 4.7e-46 156.8 3.6 6.7e-46 156.2 2.5 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 KFH44120.1 - 0.00012 21.8 11.1 0.0023 17.7 7.7 2.3 1 1 0 1 1 1 1 Right handed beta helix region NAD_binding_10 PF13460.1 KFH44121.1 - 9.6e-11 42.0 0.1 1.3e-10 41.5 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KFH44121.1 - 4.6e-06 25.7 0.1 0.0018 17.2 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein Epimerase PF01370.16 KFH44121.1 - 1.6e-05 24.4 0.0 2.5e-05 23.8 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFH44121.1 - 7e-05 21.6 0.0 0.0001 21.1 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KFH44121.1 - 0.0033 16.7 0.0 0.0049 16.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family DapB_N PF01113.15 KFH44121.1 - 0.0063 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Head_binding PF09008.5 KFH44121.1 - 0.01 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Head binding adh_short PF00106.20 KFH44121.1 - 0.095 12.6 0.4 0.41 10.5 0.3 1.9 1 1 0 1 1 1 0 short chain dehydrogenase PXA PF02194.10 KFH44122.1 - 8.5e-53 178.6 0.9 3.3e-52 176.7 0.0 2.4 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 KFH44122.1 - 4.7e-29 100.7 0.0 1.7e-28 98.9 0.0 2.1 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.19 KFH44122.1 - 8.6e-20 70.6 0.6 2.3e-19 69.2 0.4 1.8 1 0 0 1 1 1 1 PX domain RGS PF00615.14 KFH44122.1 - 8.6e-13 48.4 0.2 2.4e-12 46.9 0.1 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain Lamp PF01299.12 KFH44122.1 - 0.33 10.0 1.1 0.7 8.9 0.7 1.5 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Homoserine_dh PF00742.14 KFH44123.1 - 6.7e-52 175.7 0.0 8.7e-52 175.3 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 KFH44123.1 - 5.9e-17 62.1 0.0 9.6e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain IGPS PF00218.16 KFH44123.1 - 0.096 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase DUF2791 PF10923.3 KFH44123.1 - 0.12 10.9 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) DUF1604 PF07713.8 KFH44124.1 - 2.8e-39 132.7 1.5 8.9e-39 131.1 1.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.18 KFH44124.1 - 3.3e-06 26.7 0.4 3.3e-06 26.7 0.2 2.6 4 0 0 4 4 4 1 G-patch domain G-patch_2 PF12656.2 KFH44124.1 - 0.00084 19.1 4.6 0.00092 19.0 0.1 3.4 3 0 0 3 3 3 1 DExH-box splicing factor binding site HMG_CoA_synt_C PF08540.5 KFH44125.1 - 5.3e-70 236.1 0.0 6.7e-70 235.7 0.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KFH44125.1 - 6.1e-22 77.9 0.0 9.9e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal bZIP_1 PF00170.16 KFH44126.1 - 1.2e-12 47.5 3.0 1.2e-12 47.5 2.1 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KFH44126.1 - 1.7e-06 27.7 6.1 1.7e-06 27.7 4.2 2.2 2 0 0 2 2 2 1 Basic region leucine zipper TTKRSYEDQ PF10212.4 KFH44126.1 - 0.025 13.5 0.1 0.038 12.9 0.1 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein bZIP_Maf PF03131.12 KFH44126.1 - 0.52 10.6 14.3 0.51 10.6 1.9 2.3 2 0 0 2 2 2 0 bZIP Maf transcription factor FNIP_N PF14636.1 KFH44126.1 - 1.1 9.7 12.2 0.32 11.4 5.0 2.5 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus Macoilin PF09726.4 KFH44126.1 - 1.4 7.0 12.8 2.2 6.4 5.1 2.1 2 0 0 2 2 2 0 Transmembrane protein Methyltransf_11 PF08241.7 KFH44127.1 - 1.3e-12 48.0 0.0 3e-12 46.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH44127.1 - 1.9e-09 37.9 0.0 2.9e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH44127.1 - 9.1e-07 28.5 0.0 1.4e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFH44127.1 - 6.3e-06 26.4 0.0 1.1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH44127.1 - 9.2e-06 26.2 0.0 1.5e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH44127.1 - 0.0003 20.5 0.0 0.00049 19.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFH44127.1 - 0.0019 17.6 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KFH44127.1 - 0.03 14.3 0.1 0.076 13.0 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 KFH44127.1 - 0.045 12.8 0.0 0.07 12.2 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.10 KFH44127.1 - 0.064 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Acetyltransf_1 PF00583.19 KFH44128.1 - 3e-09 36.7 0.0 5e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFH44128.1 - 1e-07 31.9 0.0 2.1e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFH44128.1 - 0.0021 18.1 0.0 0.0031 17.5 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFH44128.1 - 0.0031 17.2 0.0 0.0075 16.0 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 KFH44128.1 - 0.0072 16.1 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Beta-lactamase PF00144.19 KFH44129.1 - 2e-41 142.1 0.0 2.7e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Fungal_trans_2 PF11951.3 KFH44130.1 - 5.9e-44 150.2 0.5 7.3e-44 149.9 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH44130.1 - 2.6e-09 36.8 7.0 4.9e-09 35.9 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box PF00646.28 KFH44131.1 - 5.6 6.7 9.2 0.78 9.4 0.1 3.4 3 0 0 3 3 3 0 F-box domain FAD_binding_2 PF00890.19 KFH44132.1 - 1.8e-43 148.9 2.5 3.5e-42 144.7 1.7 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFH44132.1 - 4.9e-12 45.4 2.2 6.9e-12 44.9 0.8 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KFH44132.1 - 5.6e-08 32.2 0.5 5.6e-08 32.2 0.4 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KFH44132.1 - 1.3e-05 23.8 2.1 0.0073 14.8 0.2 3.0 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_2 PF07992.9 KFH44132.1 - 1.3e-05 25.1 0.0 0.0073 16.2 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFH44132.1 - 2e-05 24.7 0.2 0.015 15.3 0.2 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KFH44132.1 - 0.00056 18.8 0.6 0.0028 16.5 0.4 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 KFH44132.1 - 0.0013 18.6 1.1 0.0055 16.7 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KFH44132.1 - 0.0014 17.5 0.3 0.67 8.8 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_3 PF01494.14 KFH44132.1 - 0.0031 16.6 2.8 0.19 10.7 0.1 2.6 3 0 0 3 3 3 2 FAD binding domain ADH_zinc_N PF00107.21 KFH44134.1 - 2.3e-23 82.1 0.0 3.6e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFH44134.1 - 4.2e-23 81.1 3.2 4.2e-23 81.1 2.2 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KFH44134.1 - 3.6e-05 24.6 0.0 6.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KFH44134.1 - 0.00065 18.8 0.5 0.0011 18.1 0.4 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain WD40 PF00400.27 KFH44137.1 - 5.6e-50 165.5 15.8 5e-12 45.2 0.0 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 KFH44137.1 - 3e-08 33.5 8.8 0.048 13.3 0.4 4.3 2 2 2 4 4 4 3 Transcription factor IIIC subunit delta N-term IKI3 PF04762.7 KFH44137.1 - 0.22 9.2 2.2 1.9 6.1 0.7 2.2 2 1 0 2 2 2 0 IKI3 family Ndc80_HEC PF03801.8 KFH44139.1 - 2.1e-62 209.2 0.1 2.1e-62 209.2 0.1 1.9 2 0 0 2 2 2 1 HEC/Ndc80p family FliJ PF02050.11 KFH44139.1 - 0.00088 19.3 24.3 0.065 13.2 4.3 3.2 2 1 1 3 3 3 2 Flagellar FliJ protein Synaphin PF05835.7 KFH44139.1 - 0.0015 18.6 10.3 0.0015 18.6 7.1 3.9 3 2 1 4 4 3 1 Synaphin protein DUF1664 PF07889.7 KFH44139.1 - 0.011 15.5 0.5 0.011 15.5 0.4 4.4 4 2 1 5 5 5 0 Protein of unknown function (DUF1664) TetR_C PF02909.12 KFH44139.1 - 0.013 15.1 0.1 0.049 13.2 0.1 2.0 1 0 0 1 1 1 0 Tetracyclin repressor, C-terminal all-alpha domain Tropomyosin PF00261.15 KFH44139.1 - 0.16 11.0 48.2 0.074 12.1 8.8 3.3 2 1 1 3 3 3 0 Tropomyosin Filament PF00038.16 KFH44139.1 - 0.21 11.0 44.0 0.47 9.8 14.0 2.4 2 1 0 2 2 2 0 Intermediate filament protein WASH_WAHD PF11945.3 KFH44139.1 - 0.51 9.5 8.6 0.024 13.9 1.6 1.8 2 0 0 2 2 2 0 WAHD domain of WASH complex TPR_MLP1_2 PF07926.7 KFH44139.1 - 1.6 8.4 38.2 3.1 7.5 8.0 3.6 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.7 KFH44139.1 - 1.8 8.8 12.2 1.5 9.1 0.9 3.5 3 1 1 4 4 3 0 Nucleopolyhedrovirus P10 protein Cluap1 PF10234.4 KFH44139.1 - 2.9 7.0 28.6 7.1 5.7 0.0 3.5 3 1 0 3 3 3 0 Clusterin-associated protein-1 GAS PF13851.1 KFH44139.1 - 4.1 6.5 41.0 0.3 10.2 8.8 3.2 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.1 KFH44139.1 - 5 5.9 27.9 0.77 8.6 5.3 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4407) DUF4510 PF14971.1 KFH44139.1 - 5.9 7.0 10.9 0.41 10.8 2.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4510) TMP_2 PF06791.8 KFH44139.1 - 8 6.0 9.2 2.9 7.4 0.6 2.6 3 0 0 3 3 3 0 Prophage tail length tape measure protein BCS1_N PF08740.6 KFH44140.1 - 3.1e-53 180.1 2.1 3.1e-53 180.1 1.5 2.1 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 KFH44140.1 - 7.6e-17 61.7 0.0 1.7e-08 34.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KFH44140.1 - 0.00029 20.2 0.0 0.00059 19.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFH44140.1 - 0.00037 20.2 0.0 0.0023 17.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KFH44140.1 - 0.00065 20.5 3.3 0.0079 17.0 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 KFH44140.1 - 0.0011 18.9 0.2 0.0095 15.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain TFIIF_alpha PF05793.7 KFH44140.1 - 0.0018 16.7 29.9 0.0018 16.7 20.7 2.2 2 0 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) AAA_PrkA PF08298.6 KFH44140.1 - 0.026 13.2 0.0 0.04 12.5 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain RuvB_N PF05496.7 KFH44140.1 - 0.026 13.5 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 KFH44140.1 - 0.036 13.6 7.3 4.5 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 KFH44140.1 - 0.077 12.9 1.7 0.23 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain DDRGK PF09756.4 KFH44140.1 - 5.1 6.4 37.3 14 4.9 0.0 2.5 2 0 0 2 2 2 0 DDRGK domain Apt1 PF10351.4 KFH44140.1 - 9 5.0 18.9 0.74 8.6 0.1 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain RRM_1 PF00076.17 KFH44141.1 - 5.2e-23 80.4 0.0 2e-10 40.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH44141.1 - 3.9e-18 65.1 0.0 4.7e-08 32.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH44141.1 - 1.5e-11 43.9 0.0 2.4e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ketoacyl-synt PF00109.21 KFH44143.1 - 1.9e-76 256.9 0.7 3.7e-76 255.9 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KFH44143.1 - 6.5e-66 221.4 0.4 1.6e-65 220.1 0.3 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 KFH44143.1 - 9.5e-64 215.7 1.1 1.7e-63 214.8 0.8 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 KFH44143.1 - 1.2e-51 174.9 1.1 5.9e-51 172.6 0.1 2.6 3 0 0 3 3 3 1 short chain dehydrogenase PS-DH PF14765.1 KFH44143.1 - 3.9e-43 147.7 0.0 6.7e-43 146.9 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KFH44143.1 - 9.3e-41 138.4 0.4 3.1e-40 136.7 0.1 2.2 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KFH44143.1 - 4.4e-21 74.7 0.8 1.1e-20 73.4 0.1 2.2 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFH44143.1 - 1.9e-11 44.9 0.0 7.2e-11 43.0 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFH44143.1 - 6.7e-08 32.2 0.2 1.9e-07 30.8 0.2 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 KFH44143.1 - 4.2e-06 26.9 0.1 1.1e-05 25.6 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 KFH44143.1 - 1.2e-05 24.8 0.0 2.5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KFH44143.1 - 1.7e-05 24.6 0.1 6.1e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 KFH44143.1 - 0.00047 19.1 0.0 0.0012 17.8 0.0 1.7 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Thiolase_N PF00108.18 KFH44143.1 - 0.00048 19.1 0.0 0.00099 18.1 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain 3Beta_HSD PF01073.14 KFH44143.1 - 0.001 17.8 0.0 0.002 16.9 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.15 KFH44143.1 - 0.012 15.6 0.0 0.039 14.0 0.0 1.8 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Abhydrolase_6 PF12697.2 KFH44143.1 - 0.012 15.4 0.1 0.029 14.2 0.1 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF4589 PF15252.1 KFH44143.1 - 0.024 14.4 0.1 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4589) NmrA PF05368.8 KFH44143.1 - 0.031 13.5 0.0 0.075 12.2 0.0 1.6 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.1 KFH44143.1 - 0.053 13.5 2.2 0.17 11.9 0.0 2.9 3 0 0 3 3 3 0 NADH(P)-binding F420_oxidored PF03807.12 KFH44143.1 - 0.18 12.2 2.0 0.46 10.9 0.0 2.8 4 0 0 4 4 1 0 NADP oxidoreductase coenzyme F420-dependent BAF1_ABF1 PF04684.8 KFH44143.1 - 1.3 7.7 6.4 2 7.1 4.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor bZIP_1 PF00170.16 KFH44144.1 - 6.8e-05 22.7 5.5 6.8e-05 22.7 3.8 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KFH44144.1 - 0.0043 16.8 7.2 0.0043 16.8 5.0 2.1 2 0 0 2 2 2 1 Basic region leucine zipper Stm1_N PF09598.5 KFH44144.1 - 8.8 7.1 10.6 4.8 7.9 5.6 1.9 2 0 0 2 2 2 0 Stm1 Abhydrolase_3 PF07859.8 KFH44145.1 - 2.6e-41 141.5 0.0 1e-40 139.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KFH44145.1 - 0.00085 18.0 0.0 0.0058 15.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KFH44145.1 - 0.0014 18.4 0.0 0.0027 17.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF4078 PF13300.1 KFH44147.1 - 3.3e-29 100.8 18.4 3.3e-29 100.8 12.7 3.3 2 1 0 3 3 3 1 Domain of unknown function (DUF4078) Pkinase PF00069.20 KFH44148.1 - 2.2e-77 259.7 0.0 3.9e-77 258.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH44148.1 - 2.1e-39 135.1 0.0 7.6e-39 133.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 KFH44148.1 - 8.1e-19 66.8 0.1 1.3e-18 66.1 0.1 1.3 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 KFH44148.1 - 3.8e-06 26.0 0.0 6.7e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFH44148.1 - 1.4e-05 24.2 0.0 2.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFH44148.1 - 0.01 15.2 0.1 0.026 13.8 0.0 1.6 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.4 KFH44148.1 - 0.04 13.2 0.0 0.04 13.2 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL FAD_binding_4 PF01565.18 KFH44149.1 - 1.4e-15 56.9 0.0 2.7e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain MHC_II_alpha PF00993.15 KFH44149.1 - 0.068 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Class II histocompatibility antigen, alpha domain p450 PF00067.17 KFH44150.1 - 2.3e-39 135.2 0.0 3.1e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 EnY2 PF10163.4 KFH44150.1 - 0.05 13.5 0.1 0.15 12.0 0.1 1.7 1 0 0 1 1 1 0 Transcription factor e(y)2 GSDH PF07995.6 KFH44151.1 - 2.7e-06 26.7 0.0 0.0066 15.5 0.0 2.4 2 0 0 2 2 2 2 Glucose / Sorbosone dehydrogenase NHL PF01436.16 KFH44151.1 - 0.0042 16.9 1.9 3.4 7.8 0.0 4.4 4 0 0 4 4 4 2 NHL repeat Reg_prop PF07494.6 KFH44151.1 - 0.041 13.8 0.0 0.53 10.4 0.0 2.9 2 0 0 2 2 2 0 Two component regulator propeller Transferase PF02458.10 KFH44153.1 - 1.9e-24 85.9 0.0 3.7e-24 84.9 0.0 1.4 1 1 0 1 1 1 1 Transferase family Pex14_N PF04695.8 KFH44155.1 - 1.4e-36 125.4 0.6 1.3e-35 122.4 0.0 2.6 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IncA PF04156.9 KFH44155.1 - 2.2e-05 24.1 1.7 3.2e-05 23.6 1.2 1.2 1 0 0 1 1 1 1 IncA protein zf-C4H2 PF10146.4 KFH44155.1 - 0.00039 20.5 1.0 0.00082 19.4 0.7 1.6 1 0 0 1 1 1 1 Zinc finger-containing protein HLH PF00010.21 KFH44155.1 - 0.0015 18.2 2.2 1.9 8.2 0.0 3.3 1 1 2 3 3 3 1 Helix-loop-helix DNA-binding domain CR6_interact PF10147.4 KFH44155.1 - 0.0052 16.1 0.2 0.0081 15.5 0.1 1.4 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Mnd1 PF03962.10 KFH44155.1 - 0.01 15.5 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 0 Mnd1 family Prominin PF05478.6 KFH44155.1 - 0.025 12.1 0.8 0.033 11.7 0.6 1.1 1 0 0 1 1 1 0 Prominin Myosin_tail_1 PF01576.14 KFH44155.1 - 0.031 12.0 12.1 0.042 11.5 8.4 1.0 1 0 0 1 1 1 0 Myosin tail DUF3584 PF12128.3 KFH44155.1 - 0.039 11.3 10.5 0.051 10.9 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.7 KFH44155.1 - 0.084 12.6 4.4 0.52 10.1 1.4 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.1 KFH44155.1 - 0.12 10.8 1.7 0.17 10.3 1.2 1.1 1 0 0 1 1 1 0 AAA domain DUF1043 PF06295.7 KFH44155.1 - 0.13 11.8 1.4 0.22 11.1 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) IFT57 PF10498.4 KFH44155.1 - 0.2 10.3 5.1 0.31 9.7 3.5 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 FH2 PF02181.18 KFH44155.1 - 0.2 10.4 3.6 0.32 9.8 2.5 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain Syntaxin-6_N PF09177.6 KFH44155.1 - 0.48 10.8 4.5 1 9.8 2.5 1.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF848 PF05852.6 KFH44155.1 - 0.51 10.1 7.1 0.91 9.3 4.9 1.4 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Spc7 PF08317.6 KFH44155.1 - 1.3 7.5 8.4 2 7.0 5.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein GAS PF13851.1 KFH44155.1 - 1.5 7.9 8.7 2.4 7.3 6.0 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TMPIT PF07851.8 KFH44155.1 - 1.6 7.7 4.4 2.8 6.9 3.0 1.3 1 0 0 1 1 1 0 TMPIT-like protein NPV_P10 PF05531.7 KFH44155.1 - 2 8.7 6.5 1.6 9.0 0.3 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Spectrin PF00435.16 KFH44155.1 - 3.3 8.0 8.4 5.7 7.2 4.2 2.3 2 1 0 2 2 1 0 Spectrin repeat TBPIP PF07106.8 KFH44155.1 - 4.8 6.7 7.9 1.6 8.2 1.7 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Glyco_hydro_16 PF00722.16 KFH44156.1 - 1.5e-11 43.8 0.0 2.1e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Fungal_trans_2 PF11951.3 KFH44157.1 - 4.8e-12 45.1 0.0 1.2e-08 33.9 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH44157.1 - 7.8e-08 32.1 13.0 1.7e-07 31.0 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Flu_M1_C PF08289.6 KFH44157.1 - 0.12 12.3 0.7 0.62 10.1 0.0 2.4 3 0 0 3 3 3 0 Influenza Matrix protein (M1) C-terminal domain RRM_1 PF00076.17 KFH44159.1 - 5.5e-60 198.9 0.0 4.5e-21 74.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH44159.1 - 1.1e-43 147.1 0.0 1.1e-14 54.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH44159.1 - 1.5e-30 104.7 0.0 8.9e-11 41.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFH44159.1 - 1.4e-05 24.7 0.0 0.0082 15.8 0.0 3.3 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 KFH44159.1 - 0.00092 19.1 0.0 0.84 9.6 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_3 PF08777.6 KFH44159.1 - 0.073 12.9 0.0 0.9 9.4 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif Lipase_GDSL_2 PF13472.1 KFH44160.1 - 1.6e-14 54.4 0.0 3e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Ribosomal_L29e PF01779.12 KFH44161.1 - 4.9e-22 77.5 8.5 8.3e-22 76.7 5.9 1.4 1 0 0 1 1 1 1 Ribosomal L29e protein family Cellulase PF00150.13 KFH44162.1 - 1e-13 51.1 0.2 1.9e-13 50.2 0.1 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RasGEF PF00617.14 KFH44163.1 - 2.3e-61 206.7 0.1 3.9e-61 206.0 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KFH44163.1 - 5.6e-26 90.6 0.2 1.6e-25 89.2 0.1 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 KFH44163.1 - 6.2e-16 57.5 0.1 1.4e-15 56.3 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFH44163.1 - 2.2e-14 52.7 0.2 4.6e-14 51.7 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFH44163.1 - 3.7e-13 48.7 0.1 1.1e-12 47.2 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 KFH44163.1 - 0.058 13.2 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 WW domain RRM_1 PF00076.17 KFH44164.1 - 0.0017 17.9 0.0 0.0029 17.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.5 KFH44164.1 - 0.004 17.2 0.5 0.0075 16.3 0.2 1.7 1 1 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding B-block_TFIIIC PF04182.7 KFH44164.1 - 0.048 13.4 0.0 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC RRM_5 PF13893.1 KFH44164.1 - 0.056 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.13 KFH44165.1 - 2.1e-09 37.1 10.9 4e-09 36.2 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ferric_reduct PF01794.14 KFH44166.1 - 9e-20 71.0 10.1 2.7e-19 69.4 7.0 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KFH44166.1 - 9.2e-19 67.8 0.0 5.4e-16 58.8 0.0 2.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KFH44166.1 - 1.1e-17 63.7 0.0 6.4e-17 61.3 0.0 2.1 1 1 0 1 1 1 1 FAD-binding domain DUF4405 PF14358.1 KFH44166.1 - 6.6 6.9 11.7 3.6 7.8 0.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) zf-C3HC4_2 PF13923.1 KFH44167.1 - 1.2e-09 38.0 15.2 0.0001 22.2 5.0 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFH44167.1 - 8.4e-06 25.5 14.2 0.0098 15.7 4.7 2.6 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KFH44167.1 - 1.6e-05 24.5 6.3 1.6e-05 24.5 4.3 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 KFH44167.1 - 3.3e-05 23.6 19.1 8.8e-05 22.2 4.5 2.8 3 1 0 3 3 2 2 Ring finger domain FYVE PF01363.16 KFH44167.1 - 8.6e-05 22.3 10.7 0.00012 21.8 3.1 2.5 2 0 0 2 2 2 1 FYVE zinc finger zf-RING_UBOX PF13445.1 KFH44167.1 - 0.00014 21.5 5.3 0.00014 21.5 3.7 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.20 KFH44167.1 - 0.00017 21.1 12.8 0.0018 17.9 4.0 3.0 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFH44167.1 - 0.00022 20.8 18.1 0.0085 15.7 7.5 3.2 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 KFH44167.1 - 0.0061 15.7 2.3 0.0061 15.7 1.6 2.7 2 1 1 3 3 2 1 Rtf2 RING-finger Herpes_US12 PF05363.7 KFH44167.1 - 0.063 13.7 0.0 0.063 13.7 0.0 2.2 2 0 0 2 2 2 0 Herpesvirus US12 family DUF3133 PF11331.3 KFH44167.1 - 0.39 10.3 8.3 5.5 6.6 1.7 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3133) zf-rbx1 PF12678.2 KFH44167.1 - 1.5 9.0 8.8 0.94 9.6 3.4 2.4 2 1 0 2 2 2 0 RING-H2 zinc finger zinc_ribbon_4 PF13717.1 KFH44167.1 - 2.6 7.8 8.2 14 5.5 2.1 3.6 2 1 0 2 2 2 0 zinc-ribbon domain zf-RING_6 PF14835.1 KFH44167.1 - 3.8 7.3 12.8 0.56 10.0 0.6 2.5 3 0 0 3 3 2 0 zf-RING of BARD1-type protein DUF326 PF03860.11 KFH44167.1 - 9.2 6.2 8.8 6.1 6.8 1.7 2.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF326) DUF2392 PF10288.4 KFH44168.1 - 1.2e-17 64.2 0.0 2.6e-17 63.0 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) Pkinase PF00069.20 KFH44169.1 - 4.9e-53 179.9 0.0 9.3e-53 179.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH44169.1 - 1.5e-23 83.2 0.0 2.9e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFH44169.1 - 0.00013 21.7 1.2 0.0005 19.8 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFH44169.1 - 0.0039 16.5 0.2 0.013 14.8 0.1 1.7 1 1 0 1 1 1 1 RIO1 family DUF4430 PF14478.1 KFH44169.1 - 0.091 12.8 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) SRP9-21 PF05486.7 KFH44170.1 - 3.5e-15 55.5 0.0 5e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Nuc_sug_transp PF04142.10 KFH44171.1 - 9.8e-09 34.6 0.4 1.8e-08 33.7 0.3 1.5 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 KFH44171.1 - 7.6e-07 29.2 20.7 0.0003 20.8 3.4 3.5 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 KFH44171.1 - 0.00072 18.5 4.9 0.0076 15.2 3.4 2.0 1 1 0 1 1 1 1 UAA transporter family DUF3353 PF11833.3 KFH44171.1 - 0.021 14.2 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) SUD-M PF11633.3 KFH44171.1 - 0.16 11.2 0.1 0.29 10.3 0.1 1.3 1 0 0 1 1 1 0 Single-stranded poly(A) binding domain TPT PF03151.11 KFH44171.1 - 0.57 9.8 20.4 0.096 12.3 0.9 3.2 3 1 0 3 3 3 0 Triose-phosphate Transporter family TrbC PF04956.8 KFH44171.1 - 7 6.7 12.2 1.3 9.0 1.6 3.4 3 0 0 3 3 3 0 TrbC/VIRB2 family Mito_carr PF00153.22 KFH44172.1 - 1.8e-46 155.7 0.1 1.9e-17 62.7 0.0 3.4 2 2 1 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 KFH44172.1 - 0.63 10.0 3.5 3.9 7.5 0.0 2.8 3 0 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family DCP2 PF05026.8 KFH44173.1 - 6.8e-37 125.2 0.9 1.5e-36 124.1 0.6 1.6 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 KFH44173.1 - 2.1e-16 59.7 0.0 4.1e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Fork_head PF00250.13 KFH44174.1 - 1.6e-31 108.1 0.3 3e-31 107.3 0.2 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 KFH44174.1 - 1.3e-08 34.8 0.1 3.2e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 FHA domain Acyltransferase PF01553.16 KFH44175.1 - 3.6e-13 49.0 0.0 5.3e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Yippee-Mis18 PF03226.9 KFH44177.1 - 9.7e-23 80.0 0.1 1.1e-22 79.8 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Endonuclease_7 PF02945.10 KFH44177.1 - 0.0041 16.8 1.2 0.0094 15.6 0.9 1.6 1 1 0 1 1 1 1 Recombination endonuclease VII HNH_5 PF14279.1 KFH44177.1 - 0.012 15.5 0.1 0.15 12.1 0.0 2.1 2 0 0 2 2 2 0 HNH endonuclease DUF2039 PF10217.4 KFH44177.1 - 0.026 14.5 0.6 0.097 12.6 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) zf-CHY PF05495.7 KFH44177.1 - 0.028 14.5 0.7 6.5 6.9 0.1 2.2 2 0 0 2 2 2 0 CHY zinc finger RIG-I_C-RD PF11648.3 KFH44177.1 - 0.065 13.1 0.8 0.12 12.2 0.5 1.5 1 1 0 1 1 1 0 C-terminal domain of RIG-I GFA PF04828.9 KFH44177.1 - 0.073 13.0 0.8 0.71 9.8 0.1 2.0 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme WD40 PF00400.27 KFH44178.1 - 2.8e-19 68.1 1.1 9.1e-12 44.3 0.1 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KFH44178.1 - 0.0057 15.4 0.3 1.8 7.2 0.1 2.3 2 1 1 3 3 3 2 Nup133 N terminal like Methyltransf_28 PF02636.12 KFH44179.1 - 1.4e-79 267.0 0.0 1.8e-79 266.6 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF4112 PF13430.1 KFH44180.1 - 1.7e-33 114.6 0.9 2.2e-33 114.3 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) zf-C2H2_4 PF13894.1 KFH44181.1 - 6.6e-08 32.3 9.6 0.00055 20.0 1.6 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KFH44181.1 - 1.1e-06 28.5 9.5 0.0053 17.0 1.2 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFH44181.1 - 0.0014 18.7 9.3 0.9 9.9 0.2 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-Di19 PF05605.7 KFH44181.1 - 0.59 10.2 6.8 0.26 11.4 0.5 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PPR_2 PF13041.1 KFH44183.1 - 6.9e-24 83.5 0.0 6.6e-16 58.0 0.0 3.3 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.1 KFH44183.1 - 9.8e-10 37.9 4.9 0.14 12.5 0.0 5.9 6 0 0 6 6 6 3 Pentatricopeptide repeat domain PPR PF01535.15 KFH44183.1 - 3.1e-06 26.7 2.1 0.049 13.6 0.0 5.6 7 0 0 7 7 7 1 PPR repeat PPR_1 PF12854.2 KFH44183.1 - 0.00014 21.2 0.1 5.1 6.6 0.0 4.4 4 0 0 4 4 4 2 PPR repeat MNE1 PF13762.1 KFH44183.1 - 0.04 13.9 1.0 0.11 12.6 0.1 2.1 3 0 0 3 3 3 0 Mitochondrial splicing apparatus component TPR_19 PF14559.1 KFH44183.1 - 0.046 14.0 0.2 0.3 11.4 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat YodL PF14191.1 KFH44183.1 - 0.13 12.7 0.2 1 9.9 0.1 2.3 2 0 0 2 2 2 0 YodL-like Pro_isomerase PF00160.16 KFH44184.1 - 4e-46 157.0 0.0 7.2e-46 156.2 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.10 KFH44184.1 - 0.00013 21.8 0.1 0.00072 19.4 0.0 2.3 3 0 0 3 3 3 1 U-box domain PAP_central PF04928.12 KFH44186.1 - 5.4e-103 343.2 0.0 9.6e-103 342.4 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 KFH44186.1 - 6.7e-46 155.6 0.0 3.4e-45 153.3 0.0 2.2 2 1 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 KFH44186.1 - 2.2e-08 34.3 0.1 5.5e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap PF03813.9 KFH44186.1 - 0.091 10.2 0.0 0.16 9.4 0.0 1.3 1 0 0 1 1 1 0 Nrap protein DNA_pol_B_palm PF14792.1 KFH44186.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase beta palm Ribonuc_red_sm PF00268.16 KFH44187.1 - 5.9e-118 392.9 3.1 7.3e-118 392.6 2.1 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Fungal_trans PF04082.13 KFH44189.1 - 2.3e-16 59.4 0.7 4.2e-16 58.6 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 KFH44189.1 - 3.3e-07 30.2 12.4 0.0001 22.3 4.0 3.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFH44189.1 - 0.00051 20.1 15.2 0.039 14.2 4.9 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KFH44189.1 - 0.0011 19.1 16.7 0.19 12.1 5.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-CHY PF05495.7 KFH44189.1 - 0.041 14.0 2.2 0.11 12.6 1.6 1.6 1 0 0 1 1 1 0 CHY zinc finger Cytochrome_C7 PF14522.1 KFH44189.1 - 0.23 11.1 3.7 0.29 10.7 1.4 1.9 2 0 0 2 2 2 0 Cytochrome c7 Mito_carr PF00153.22 KFH44190.1 - 2.2e-53 177.9 3.0 1.4e-18 66.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein PH PF00169.24 KFH44191.1 - 3.9e-26 91.2 0.2 1.2e-12 47.8 0.1 2.3 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 KFH44191.1 - 1.8e-14 53.9 3.9 1.4e-08 34.9 0.0 3.6 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 KFH44191.1 - 3.4e-08 33.6 1.3 0.00024 21.2 0.2 3.8 2 2 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.1 KFH44191.1 - 0.00064 19.5 0.0 0.006 16.4 0.0 2.2 2 0 0 2 2 2 1 PH domain PH_8 PF15409.1 KFH44191.1 - 0.00065 19.7 0.1 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain SCA7 PF08313.7 KFH44192.1 - 8.2e-35 118.2 0.9 2.6e-34 116.6 0.7 1.9 1 0 0 1 1 1 1 SCA7, zinc-binding domain Omega-toxin PF06357.6 KFH44192.1 - 0.11 12.0 0.1 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 Omega-atracotoxin CDC45 PF02724.9 KFH44192.1 - 1.2 7.0 9.0 1.5 6.7 6.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Menin PF05053.8 KFH44192.1 - 1.5 6.9 10.2 2 6.4 7.1 1.2 1 0 0 1 1 1 0 Menin DUF2985 PF11204.3 KFH44193.1 - 7.4e-19 67.2 0.0 7.4e-19 67.2 0.0 2.1 2 1 1 3 3 3 1 Protein of unknown function (DUF2985) Bax1-I PF01027.15 KFH44193.1 - 0.1 12.1 0.9 0.22 11.1 0.6 1.5 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Cytochrom_B_N_2 PF13631.1 KFH44193.1 - 0.16 11.7 1.9 0.25 11.1 1.3 1.2 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB PepSY_TM PF03929.11 KFH44193.1 - 0.68 10.4 4.9 0.69 10.4 0.7 2.7 2 0 0 2 2 2 0 PepSY-associated TM helix SAM_2 PF07647.12 KFH44194.1 - 6.7e-11 41.8 0.1 1.2e-10 41.0 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFH44194.1 - 1.1e-06 28.6 0.2 2.3e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.5 KFH44194.1 - 0.21 11.5 0.2 0.55 10.1 0.1 1.6 1 0 0 1 1 1 0 IGR protein motif Tubulin_3 PF14881.1 KFH44195.1 - 5.6e-73 244.2 0.1 9.9e-73 243.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 KFH44195.1 - 1.4e-23 83.1 0.0 3.1e-23 82.0 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 KFH44195.1 - 0.0093 15.8 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Mito_carr PF00153.22 KFH44196.1 - 7.8e-59 195.4 2.1 5.3e-19 67.7 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein AhpC-TSA_2 PF13911.1 KFH44197.1 - 2.6e-12 46.6 0.0 3.4e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 KFH44197.1 - 0.062 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family RRM_6 PF14259.1 KFH44198.1 - 0.039 13.9 0.0 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) K_oxygenase PF13434.1 KFH44198.1 - 0.045 12.6 0.2 0.064 12.1 0.1 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pkinase PF00069.20 KFH44199.1 - 7.6e-59 198.9 0.0 1.2e-58 198.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH44199.1 - 5e-26 91.3 0.0 9.1e-26 90.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH44199.1 - 0.0041 16.1 0.0 0.0069 15.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFH44199.1 - 0.23 11.1 0.0 0.23 11.1 0.0 2.9 2 1 0 3 3 3 0 Phosphotransferase enzyme family Mnd1 PF03962.10 KFH44199.1 - 3.9 7.0 8.9 4.8 6.7 5.3 1.7 2 0 0 2 2 2 0 Mnd1 family CLU PF13236.1 KFH44200.1 - 3.3e-80 268.6 0.0 5.3e-80 267.9 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 KFH44200.1 - 1e-51 175.2 0.0 6e-51 172.7 0.0 2.2 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 KFH44200.1 - 8.1e-22 77.1 0.0 1.8e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 KFH44200.1 - 3.4e-21 74.9 10.7 2.4e-10 40.1 0.1 3.7 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 KFH44200.1 - 2.4e-14 52.6 11.7 2.8e-05 23.8 0.1 5.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFH44200.1 - 5.7e-06 25.8 9.2 0.038 13.6 1.0 3.9 3 1 0 4 4 4 2 TPR repeat TPR_8 PF13181.1 KFH44200.1 - 0.0029 17.2 4.6 0.14 11.9 0.4 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFH44200.1 - 0.015 15.2 0.2 0.015 15.2 0.1 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF727 PF05303.7 KFH44200.1 - 0.1 12.3 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF727) ubiquitin PF00240.18 KFH44200.1 - 0.12 11.7 0.0 0.28 10.6 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family TPR_17 PF13431.1 KFH44200.1 - 0.32 11.3 4.6 33 5.0 0.0 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFH44200.1 - 0.75 10.5 8.2 2.4 8.9 0.8 3.9 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFH44200.1 - 4.3 8.0 5.5 33 5.2 0.1 3.6 2 1 0 2 2 2 0 Tetratricopeptide repeat Septin PF00735.13 KFH44201.1 - 4.4e-13 48.8 0.1 5.3e-10 38.7 0.0 2.1 2 0 0 2 2 2 2 Septin AAA_16 PF13191.1 KFH44201.1 - 0.0002 21.4 0.0 0.00049 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.1 KFH44201.1 - 0.016 14.8 0.0 0.06 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KFH44201.1 - 0.022 15.2 0.0 0.042 14.3 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein DUF258 PF03193.11 KFH44201.1 - 0.024 13.8 0.0 0.056 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA PF00004.24 KFH44201.1 - 0.027 14.6 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KFH44201.1 - 0.031 15.0 0.1 0.065 14.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 KFH44201.1 - 0.034 13.7 0.2 0.1 12.2 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.1 KFH44201.1 - 0.038 13.5 0.1 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 KFH44201.1 - 0.079 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 KFH44201.1 - 0.1 12.8 0.0 0.27 11.5 0.0 1.7 2 0 0 2 2 2 0 ABC transporter AAA_22 PF13401.1 KFH44201.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 KFH44201.1 - 0.17 11.4 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ORC6 PF05460.8 KFH44201.1 - 0.23 10.5 2.9 0.35 9.9 2.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Lung_7-TM_R PF06814.8 KFH44202.1 - 1e-70 238.0 14.5 1.2e-70 237.8 10.0 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF4492 PF14899.1 KFH44202.1 - 0.066 12.7 2.0 0.19 11.2 1.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) PrgI PF12666.2 KFH44202.1 - 1.6 8.9 19.4 1 9.5 2.0 3.5 1 1 1 3 3 3 0 PrgI family protein Sen15 PF09631.5 KFH44203.1 - 1.6e-28 98.9 0.0 1.8e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Sen15 protein Pkinase PF00069.20 KFH44204.1 - 2e-77 259.8 0.0 2.7e-77 259.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH44204.1 - 2.3e-38 131.7 0.0 3.5e-38 131.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_C2 PF00648.16 KFH44205.1 - 7.2e-21 74.4 0.0 1.1e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 KFH44205.1 - 5.4e-16 58.5 0.0 2.5e-15 56.3 0.0 2.1 2 1 0 2 2 2 1 Calpain large subunit, domain III MIT PF04212.13 KFH44205.1 - 0.024 14.4 0.4 0.044 13.6 0.3 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain adh_short PF00106.20 KFH44206.1 - 2.4e-30 105.6 2.6 3.1e-30 105.3 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH44206.1 - 2.2e-25 89.8 0.0 2.6e-25 89.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH44206.1 - 9.2e-14 51.5 1.4 1.4e-13 50.9 1.0 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KFH44206.1 - 0.0023 17.6 1.0 0.0037 16.9 0.7 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.18 KFH44206.1 - 0.12 12.2 0.7 0.99 9.2 0.5 2.1 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Herpes_gE PF02480.11 KFH44207.1 - 0.074 11.3 0.0 0.083 11.1 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E MFS_1 PF07690.11 KFH44208.1 - 1.5e-27 96.2 41.0 2e-27 95.8 28.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DDHD PF02862.12 KFH44209.1 - 1.6e-37 129.5 0.1 3.1e-19 69.7 0.0 2.9 2 1 0 3 3 3 2 DDHD domain Abhydrolase_6 PF12697.2 KFH44209.1 - 0.00084 19.2 1.0 0.0018 18.1 0.1 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF2305 PF10230.4 KFH44209.1 - 0.047 13.1 0.0 0.092 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) SH3_3 PF08239.6 KFH44210.1 - 0.0001 22.3 0.2 0.00022 21.3 0.1 1.5 1 1 0 1 1 1 1 Bacterial SH3 domain DUF2424 PF10340.4 KFH44211.1 - 4.8e-25 87.9 0.0 6.8e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 KFH44211.1 - 8.7e-25 87.5 0.2 1.1e-24 87.2 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFH44211.1 - 0.009 15.7 0.1 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 KFH44211.1 - 0.018 14.4 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Peptidase_S9 PF00326.16 KFH44211.1 - 0.044 12.9 0.0 0.13 11.4 0.0 1.7 1 1 1 2 2 2 0 Prolyl oligopeptidase family BAAT_C PF08840.6 KFH44211.1 - 0.069 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal COesterase PF00135.23 KFH44211.1 - 0.14 10.8 0.3 1.5 7.4 0.0 2.0 2 0 0 2 2 2 0 Carboxylesterase family Mus7 PF09462.5 KFH44212.1 - 6.3e-131 438.2 0.0 9.9e-131 437.5 0.0 1.3 1 0 0 1 1 1 1 Mus7/MMS22 family Peptidase_C48 PF02902.14 KFH44213.1 - 9.3e-20 71.1 0.0 1.6e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain PTR2 PF00854.16 KFH44214.1 - 5.1e-15 55.1 1.8 2.6e-12 46.2 0.1 2.0 2 0 0 2 2 2 2 POT family BPD_transp_2 PF02653.11 KFH44214.1 - 0.02 13.8 0.7 0.024 13.5 0.5 1.1 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component Peptidase_S8 PF00082.17 KFH44216.1 - 2.2e-47 161.5 18.2 3.1e-47 161.0 12.6 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KFH44216.1 - 7.6e-19 68.0 0.1 1.4e-18 67.1 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Zn_clus PF00172.13 KFH44217.1 - 3.2e-09 36.5 8.6 5.7e-09 35.7 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFH44217.1 - 7.6e-08 31.3 0.0 7.9e-07 27.9 0.0 2.2 1 1 2 3 3 3 1 Fungal specific transcription factor domain DUF3712 PF12505.3 KFH44220.1 - 3.8e-23 81.8 0.0 7.2e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) OppC_N PF12911.2 KFH44220.1 - 0.29 10.5 3.4 0.54 9.6 2.4 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C ATP-synt_ab PF00006.20 KFH44221.1 - 1.5e-60 204.3 0.0 2.2e-60 203.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KFH44221.1 - 7.9e-27 93.9 0.6 1.7e-26 92.8 0.4 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KFH44221.1 - 1.2e-23 83.0 0.5 3.8e-23 81.4 0.3 1.9 2 0 0 2 2 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_22 PF13401.1 KFH44221.1 - 0.006 16.7 0.0 0.03 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KFH44221.1 - 0.006 16.3 0.0 0.018 14.7 0.0 1.7 2 0 0 2 2 2 1 Archaeal ATPase AAA_25 PF13481.1 KFH44221.1 - 0.011 15.1 0.1 0.046 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KFH44221.1 - 0.022 14.4 0.2 1.1 8.9 0.0 2.7 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KFH44221.1 - 0.025 14.2 0.1 0.065 12.8 0.0 1.8 2 0 0 2 2 2 0 NACHT domain DUF258 PF03193.11 KFH44221.1 - 0.031 13.4 0.1 0.056 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 KFH44221.1 - 0.044 13.7 0.2 0.4 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 KFH44221.1 - 0.048 13.8 0.2 4.4 7.5 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 KFH44221.1 - 0.049 12.7 0.1 0.08 12.0 0.1 1.4 1 0 0 1 1 1 0 KaiC RNA_helicase PF00910.17 KFH44221.1 - 0.07 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 KFH44221.1 - 0.13 11.0 0.8 0.69 8.7 0.1 2.1 2 0 0 2 2 2 0 NB-ARC domain Cupin_8 PF13621.1 KFH44222.1 - 4.6e-34 118.0 0.0 7.3e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.9 KFH44222.1 - 6.6e-15 55.1 0.0 3.1e-14 52.9 0.0 1.9 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.1 KFH44222.1 - 1.1e-06 28.2 0.3 0.00025 20.7 0.1 3.3 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_3 PF13415.1 KFH44222.1 - 6.3e-06 26.1 1.7 0.0036 17.4 0.1 3.7 3 0 0 3 3 3 1 Galactose oxidase, central domain Cupin_4 PF08007.7 KFH44222.1 - 0.0022 17.2 0.1 0.004 16.4 0.1 1.3 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_5 PF13854.1 KFH44222.1 - 0.015 15.2 0.0 2.2 8.2 0.0 2.6 2 0 0 2 2 2 0 Kelch motif COX4 PF02936.9 KFH44223.1 - 4.8e-50 168.9 0.1 5.6e-50 168.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1104 PF06518.6 KFH44223.1 - 0.15 12.2 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) DSPc PF00782.15 KFH44224.1 - 4.7e-25 87.7 0.0 3.4e-21 75.2 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFH44224.1 - 0.00037 19.9 0.0 0.0014 18.0 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Pyr_redox_3 PF13738.1 KFH44225.1 - 1.9e-23 83.5 0.0 2.8e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFH44225.1 - 5.3e-10 39.1 0.0 4.7e-08 32.9 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 KFH44225.1 - 1.6e-09 36.5 0.0 2.9e-08 32.3 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Thi4 PF01946.12 KFH44225.1 - 3.6e-06 26.2 0.0 0.00021 20.4 0.0 2.2 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.1 KFH44225.1 - 7e-05 21.8 0.0 0.00085 18.3 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KFH44225.1 - 9.9e-05 21.3 0.0 0.0044 15.9 0.0 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFH44225.1 - 0.00046 20.5 0.0 0.23 11.8 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFH44225.1 - 0.0039 17.0 0.1 2.2 8.0 0.2 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFH44225.1 - 0.024 14.4 0.1 0.8 9.4 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KFH44225.1 - 0.049 12.4 0.1 0.37 9.5 0.0 2.3 3 0 0 3 3 3 0 FAD binding domain Lycopene_cycl PF05834.7 KFH44225.1 - 0.054 12.4 0.1 0.55 9.0 0.0 2.3 3 0 0 3 3 3 0 Lycopene cyclase protein Shikimate_DH PF01488.15 KFH44225.1 - 0.066 13.3 0.0 1.5 8.9 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase AAA_2 PF07724.9 KFH44226.1 - 3.9e-33 114.7 0.0 1.3e-32 113.1 0.0 1.9 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KFH44226.1 - 2.9e-13 50.1 0.2 6.6e-13 49.0 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KFH44226.1 - 5e-09 35.9 0.0 1.1e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 KFH44226.1 - 2.3e-07 30.6 0.0 5.9e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KFH44226.1 - 9.9e-05 22.4 0.0 0.0062 16.5 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KFH44226.1 - 0.00015 22.6 0.8 0.00038 21.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KFH44226.1 - 0.00041 20.2 0.0 0.00079 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain MCM PF00493.18 KFH44226.1 - 0.00055 18.8 0.9 0.0013 17.6 0.0 1.8 2 0 0 2 2 2 1 MCM2/3/5 family AAA_22 PF13401.1 KFH44226.1 - 0.00073 19.6 0.6 0.0028 17.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KFH44226.1 - 0.0038 16.6 0.0 0.0083 15.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein T2SE PF00437.15 KFH44226.1 - 0.011 14.6 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein ATP-synt_ab PF00006.20 KFH44226.1 - 0.075 12.5 0.1 2.7 7.4 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.1 KFH44226.1 - 0.079 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 KFH44226.1 - 0.092 13.0 1.1 0.2 11.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KFH44226.1 - 0.098 12.2 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KFH44226.1 - 0.15 12.3 0.9 0.21 11.8 0.0 1.7 2 0 0 2 2 2 0 ABC transporter AAA PF00004.24 KFH44227.1 - 6.1e-39 133.2 0.0 1.5e-37 128.7 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFH44227.1 - 1.9e-06 27.9 0.0 0.0031 17.5 0.0 3.3 1 1 1 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 KFH44227.1 - 4e-06 26.9 0.1 0.0032 17.5 0.1 3.2 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KFH44227.1 - 5.2e-06 25.6 0.0 1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KFH44227.1 - 5.3e-05 23.1 0.0 0.01 15.7 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 KFH44227.1 - 0.00023 21.9 0.1 0.00082 20.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KFH44227.1 - 0.00068 19.5 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFH44227.1 - 0.0032 17.2 0.1 0.0076 15.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KFH44227.1 - 0.0042 16.2 0.0 0.015 14.4 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KFH44227.1 - 0.0047 16.3 0.0 0.0087 15.4 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 KFH44227.1 - 0.0088 15.7 0.1 0.027 14.2 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 KFH44227.1 - 0.01 15.2 0.3 0.23 10.8 0.1 2.3 1 1 1 2 2 2 0 AAA domain TIP49 PF06068.8 KFH44227.1 - 0.013 14.2 0.0 0.022 13.4 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus DUF815 PF05673.8 KFH44227.1 - 0.02 13.8 0.0 0.038 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 KFH44227.1 - 0.031 14.5 0.0 0.097 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KFH44227.1 - 0.043 13.9 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 KFH44227.1 - 0.046 13.2 0.3 0.1 12.1 0.2 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KFH44227.1 - 0.055 12.5 0.6 0.15 11.1 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.1 KFH44227.1 - 0.068 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 KFH44227.1 - 0.08 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.7 KFH44227.1 - 0.097 12.3 0.1 0.26 10.9 0.0 1.7 2 0 0 2 2 1 0 NACHT domain AAA_10 PF12846.2 KFH44227.1 - 0.11 11.8 0.2 14 5.0 0.0 2.7 2 1 0 3 3 3 0 AAA-like domain ABC_tran PF00005.22 KFH44227.1 - 0.15 12.4 0.0 0.55 10.5 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Sigma54_activ_2 PF14532.1 KFH44227.1 - 0.2 11.6 0.0 0.49 10.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.1 KFH44227.1 - 0.22 11.0 0.1 0.39 10.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 KFH44227.1 - 0.22 11.4 0.0 0.42 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) PhoH PF02562.11 KFH44227.1 - 0.35 10.0 0.2 0.83 8.8 0.1 1.6 1 1 1 2 2 2 0 PhoH-like protein Transket_pyr PF02779.19 KFH44228.1 - 7.2e-62 208.0 0.0 1.2e-61 207.3 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 KFH44228.1 - 3.9e-55 186.6 0.0 5.4e-55 186.2 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component MFS_1 PF07690.11 KFH44229.1 - 1.9e-23 82.7 70.5 9.4e-18 64.0 24.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Spore_YtfJ PF09579.5 KFH44229.1 - 0.16 11.8 0.8 2 8.3 0.0 2.6 2 0 0 2 2 2 0 Sporulation protein YtfJ (Spore_YtfJ) adh_short PF00106.20 KFH44231.1 - 1.1e-29 103.5 0.3 2.1e-29 102.6 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH44231.1 - 1.6e-11 44.1 1.0 5.9e-11 42.3 0.7 1.9 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFH44231.1 - 6.8e-08 32.5 0.0 3.6e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 KFH44231.1 - 5.9e-05 21.9 0.0 8.7e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 2-Hacid_dh_C PF02826.14 KFH44231.1 - 0.0048 16.0 0.0 0.0074 15.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.16 KFH44231.1 - 0.0054 16.2 0.0 0.0094 15.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family EthD PF07110.6 KFH44232.1 - 1.9e-23 83.1 0.0 6.9e-23 81.4 0.0 1.7 2 0 0 2 2 2 1 EthD domain DUF1227 PF06777.6 KFH44233.1 - 1e-62 210.1 1.6 1.3e-62 209.8 0.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 KFH44233.1 - 2.8e-50 170.0 0.3 5e-50 169.2 0.2 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 KFH44233.1 - 2.5e-44 151.1 0.0 7.1e-44 149.6 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain SNF2_N PF00176.18 KFH44233.1 - 7.3e-05 21.7 0.0 0.00037 19.3 0.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 KFH44233.1 - 0.0016 17.9 0.0 0.29 10.6 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KFH44233.1 - 0.031 14.0 0.2 0.16 11.8 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KFH44233.1 - 0.055 13.6 0.1 3.4 7.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 KFH44233.1 - 0.056 12.6 0.1 2.8 7.1 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein DUF1996 PF09362.5 KFH44234.1 - 2.6e-90 302.2 0.2 3.2e-90 301.8 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) PTR2 PF00854.16 KFH44235.1 - 0.046 12.4 0.1 0.063 12.0 0.1 1.2 1 0 0 1 1 1 0 POT family p450 PF00067.17 KFH44236.1 - 4.4e-78 262.8 0.0 5.5e-78 262.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Transferase PF02458.10 KFH44237.1 - 4.1e-07 28.8 0.0 1.8e-06 26.7 0.0 1.9 2 1 0 2 2 2 1 Transferase family Dicty_CAR PF05462.6 KFH44238.1 - 6.1e-09 35.1 9.7 1.1e-08 34.3 6.7 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.16 KFH44238.1 - 2.6e-07 30.0 3.5 3.6e-07 29.5 2.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.3 KFH44238.1 - 2.6e-06 27.1 11.2 5.8e-06 26.0 7.7 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7TM_GPCR_Srsx PF10320.4 KFH44238.1 - 0.00099 18.3 8.0 0.0014 17.8 5.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx FAD_binding_3 PF01494.14 KFH44239.1 - 1.4e-73 247.9 0.0 2.1e-73 247.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KFH44239.1 - 2.2e-38 131.5 0.1 3.4e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox PF00070.22 KFH44239.1 - 0.00041 20.6 0.0 0.0047 17.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFH44239.1 - 0.01 15.8 0.0 0.028 14.4 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFH44239.1 - 0.024 14.5 0.0 0.088 12.6 0.0 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.1 KFH44239.1 - 0.039 14.2 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain DAO PF01266.19 KFH44239.1 - 0.061 12.2 0.0 0.31 9.9 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pkinase PF00069.20 KFH44240.1 - 1.4e-29 103.0 0.0 1.7e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH44240.1 - 3.3e-09 36.2 0.1 5.3e-08 32.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase FAD_binding_4 PF01565.18 KFH44241.1 - 1.4e-25 89.3 5.7 8e-25 86.9 4.3 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KFH44241.1 - 1.3e-12 47.3 0.1 2.5e-12 46.4 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like RGS PF00615.14 KFH44242.1 - 4.4e-12 46.1 0.0 6.8e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Abhydrolase_3 PF07859.8 KFH44243.1 - 1.3e-25 90.1 0.1 1.7e-25 89.8 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KFH44243.1 - 3.4e-09 35.8 0.0 6.6e-09 34.8 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KFH44243.1 - 0.00033 20.4 0.3 0.00051 19.8 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DHC_N1 PF08385.7 KFH44244.1 - 1.5e-11 43.3 4.2 0.00016 20.1 0.1 4.9 3 1 2 5 5 5 3 Dynein heavy chain, N-terminal region 1 RPW8 PF05659.6 KFH44244.1 - 0.0028 17.2 10.4 1.1 8.7 0.1 6.0 4 1 3 7 7 7 2 Arabidopsis broad-spectrum mildew resistance protein RPW8 Proteasom_Rpn13 PF04683.8 KFH44244.1 - 0.0081 16.2 0.0 1.8 8.7 0.0 3.2 3 0 0 3 3 3 1 Proteasome complex subunit Rpn13 ubiquitin receptor Ret_tiss PF10044.4 KFH44244.1 - 0.015 15.8 0.5 2.2e+02 2.4 0.0 5.8 2 2 4 7 7 7 0 Retinal tissue protein Glutaredoxin2_C PF04399.8 KFH44244.1 - 0.13 11.8 9.4 25 4.4 0.1 5.7 5 0 0 5 5 5 0 Glutaredoxin 2, C terminal domain CHMI PF02962.10 KFH44244.1 - 0.14 12.2 1.4 7 6.7 0.0 3.6 3 2 0 3 3 3 0 5-carboxymethyl-2-hydroxymuconate isomerase DUF2664 PF10867.3 KFH44244.1 - 0.16 12.5 6.9 19 5.9 0.0 5.1 7 0 0 7 7 7 0 Protein of unknown function (DUF2664) DUF4175 PF13779.1 KFH44244.1 - 1.1 6.8 6.7 1.7 6.2 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4477 PF14780.1 KFH44244.1 - 1.6 8.0 4.4 96 2.2 0.0 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF4477) DAO PF01266.19 KFH44246.1 - 5e-51 173.6 0.0 7.3e-51 173.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFH44246.1 - 3e-07 29.6 0.6 1e-06 27.8 0.4 1.8 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KFH44246.1 - 3e-07 29.8 0.0 9.7e-06 24.9 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFH44246.1 - 0.00053 19.9 0.0 0.0033 17.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFH44246.1 - 0.011 15.7 0.2 0.034 14.1 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 KFH44246.1 - 0.015 14.9 0.1 0.029 14.0 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 KFH44246.1 - 0.018 14.1 0.0 0.82 8.6 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 KFH44246.1 - 0.023 13.1 0.3 0.036 12.5 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 KFH44246.1 - 0.026 13.3 0.1 0.06 12.2 0.1 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.22 KFH44246.1 - 0.029 14.7 0.2 0.14 12.5 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFH44246.1 - 0.045 12.6 0.0 0.45 9.3 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein CRAL_TRIO PF00650.15 KFH44247.1 - 2.9e-41 140.5 0.0 4.9e-41 139.8 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KFH44247.1 - 1.8e-12 47.2 1.0 6e-12 45.5 0.0 2.4 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KFH44247.1 - 1.7e-10 41.0 0.0 2.7e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF1843 PF08898.5 KFH44247.1 - 0.0042 17.1 0.6 0.01 15.8 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1843) DUF3189 PF11385.3 KFH44247.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3189) CUE PF02845.11 KFH44247.1 - 0.12 11.8 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 CUE domain MFS_1 PF07690.11 KFH44248.1 - 8.1e-48 162.9 35.4 8.1e-48 162.9 24.6 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH44248.1 - 2.2e-17 62.7 5.3 2.2e-17 62.7 3.7 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter BT1 PF03092.11 KFH44248.1 - 0.0025 16.5 3.0 0.027 13.1 0.0 2.2 2 0 0 2 2 2 2 BT1 family PTR2 PF00854.16 KFH44248.1 - 0.24 10.1 8.2 0.048 12.4 0.2 2.8 2 1 1 3 3 3 0 POT family WD40 PF00400.27 KFH44249.1 - 4.9e-06 26.2 3.0 0.0014 18.3 0.0 3.6 4 0 0 4 4 4 2 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KFH44249.1 - 0.012 15.0 0.2 2.1 7.8 0.0 3.2 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.9 KFH44249.1 - 0.013 14.3 0.0 0.11 11.3 0.0 2.0 2 0 0 2 2 2 0 Coatomer WD associated region Hira PF07569.6 KFH44249.1 - 0.072 12.2 0.0 0.2 10.8 0.0 1.7 2 0 0 2 2 2 0 TUP1-like enhancer of split Alpha-amylase_C PF02806.13 KFH44250.1 - 4.7e-27 93.9 0.1 1.2e-26 92.6 0.1 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 KFH44250.1 - 7.6e-19 68.2 0.3 7.7e-15 55.0 0.2 2.6 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 KFH44250.1 - 7e-16 58.0 0.0 1.7e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) hDGE_amylase PF14701.1 KFH44250.1 - 0.083 11.7 0.1 0.14 11.0 0.1 1.2 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Zn_clus PF00172.13 KFH44252.1 - 1.3e-07 31.3 13.8 1.3e-07 31.3 9.5 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFH44252.1 - 0.00033 19.3 0.1 0.00048 18.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain BSD PF03909.12 KFH44253.1 - 5e-25 87.0 3.9 1.6e-13 50.1 0.0 3.1 3 0 0 3 3 3 2 BSD domain TFIIH_BTF_p62_N PF08567.6 KFH44253.1 - 4.8e-24 83.7 0.0 1.2e-23 82.5 0.0 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain WD40 PF00400.27 KFH44254.1 - 4.1e-42 140.5 23.5 4.6e-11 42.1 0.5 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KFH44254.1 - 0.00063 19.1 0.2 6.4 6.3 0.0 4.8 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Rick_17kDa_Anti PF05433.10 KFH44255.1 - 0.0013 18.3 5.3 0.36 10.5 0.4 2.2 2 0 0 2 2 2 2 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.1 KFH44255.1 - 0.015 14.7 2.5 0.029 13.8 1.7 1.5 1 1 0 1 1 1 0 YMGG-like Gly-zipper DUF4235 PF14019.1 KFH44255.1 - 0.1 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) PQ-loop PF04193.9 KFH44256.1 - 1.1e-17 63.2 2.5 9.2e-12 44.3 0.2 2.6 2 0 0 2 2 2 2 PQ loop repeat WSC PF01822.14 KFH44257.1 - 2.2e-12 46.7 6.0 2.2e-12 46.7 4.2 2.3 3 0 0 3 3 3 1 WSC domain SSP160 PF06933.6 KFH44257.1 - 5.7 4.7 7.6 11 3.9 5.3 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Glyco_hydro_18 PF00704.23 KFH44258.1 - 1.7e-53 182.3 3.3 2.6e-53 181.6 2.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 KFH44258.1 - 2.7e-20 71.9 0.1 2.8e-08 33.5 0.0 3.6 3 0 0 3 3 3 3 LysM domain Chitin_bind_1 PF00187.14 KFH44258.1 - 4.1e-05 23.4 3.0 4.1e-05 23.4 2.1 4.0 3 0 0 3 3 3 1 Chitin recognition protein Mito_fiss_reg PF05308.6 KFH44259.1 - 8.5 5.6 6.9 13 5.0 4.8 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Fungal_trans PF04082.13 KFH44261.1 - 2.3e-13 49.6 0.1 1.5e-10 40.3 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH44261.1 - 1.8e-07 30.9 11.6 3.1e-07 30.2 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_18 PF00704.23 KFH44262.1 - 2e-49 168.8 0.0 2.4e-49 168.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 NAD_binding_11 PF14833.1 KFH44263.1 - 3.5e-37 127.1 0.1 1e-25 90.1 0.0 2.5 2 1 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 KFH44263.1 - 5.2e-37 127.2 0.1 8.5e-37 126.5 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KFH44263.1 - 7.8e-05 23.0 0.0 0.00031 21.0 0.0 2.1 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 KFH44263.1 - 0.00021 20.9 0.0 0.0004 20.1 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KFH44263.1 - 0.039 13.3 0.0 1.1 8.6 0.0 2.7 2 1 1 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 KFH44263.1 - 0.044 13.2 0.0 0.16 11.4 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Glyco_hydro_1 PF00232.13 KFH44264.1 - 6e-152 505.9 0.0 6.8e-152 505.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_cc PF11790.3 KFH44264.1 - 0.0007 19.0 0.0 0.0021 17.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase catalytic core Sugar_tr PF00083.19 KFH44265.1 - 5.8e-107 358.0 17.9 6.8e-107 357.8 12.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH44265.1 - 3.5e-20 72.0 39.8 2.2e-16 59.5 9.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Aa_trans PF01490.13 KFH44266.1 - 1.4e-45 155.4 31.8 1.6e-45 155.3 22.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PLDc_2 PF13091.1 KFH44268.1 - 6.4e-19 67.9 0.0 2.3e-09 37.0 0.0 2.1 2 0 0 2 2 2 2 PLD-like domain PQ-loop PF04193.9 KFH44269.1 - 4.6e-31 106.1 8.4 4.5e-15 54.9 2.8 2.5 2 0 0 2 2 2 2 PQ loop repeat Form_Nir_trans PF01226.12 KFH44269.1 - 0.22 10.4 2.1 0.37 9.6 0.2 1.9 2 0 0 2 2 2 0 Formate/nitrite transporter Cyt-b5 PF00173.23 KFH44270.1 - 1.2e-13 50.6 0.0 2.7e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IDO PF01231.13 KFH44270.1 - 1.3e-10 40.2 0.0 5.6e-10 38.2 0.0 1.9 2 0 0 2 2 2 1 Indoleamine 2,3-dioxygenase FAD_binding_1 PF00667.15 KFH44270.1 - 4.6e-10 39.3 0.0 1.2e-09 37.9 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KFH44270.1 - 1.3e-08 35.4 0.0 2.9e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain SecA_SW PF07516.8 KFH44270.1 - 0.31 10.7 0.0 0.75 9.5 0.0 1.6 1 0 0 1 1 1 0 SecA Wing and Scaffold domain Dynamin_N PF00350.18 KFH44271.1 - 0.028 14.2 0.0 0.041 13.7 0.0 1.2 1 0 0 1 1 1 0 Dynamin family CwfJ_C_1 PF04677.10 KFH44275.1 - 1.9e-25 88.8 0.0 3.1e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 KFH44275.1 - 1.1e-20 73.9 0.0 3.7e-20 72.2 0.0 2.0 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Zn_clus PF00172.13 KFH44276.1 - 4.2e-08 32.9 9.4 1e-07 31.7 6.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFH44276.1 - 0.00021 19.9 0.0 0.00052 18.7 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3808 PF10300.4 KFH44277.1 - 1.6e-114 383.0 0.0 2.2e-114 382.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_16 PF13432.1 KFH44277.1 - 0.13 12.9 11.6 3.7 8.3 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFH44277.1 - 1.1 9.8 4.1 1.1e+02 3.6 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Acetyltransf_1 PF00583.19 KFH44278.1 - 0.0044 17.0 0.0 0.012 15.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Mpv17_PMP22 PF04117.7 KFH44279.1 - 5.6e-23 80.3 0.3 1.9e-22 78.6 0.1 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family IDO PF01231.13 KFH44280.1 - 1.4e-115 386.1 0.0 1.6e-115 385.9 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.6 KFH44280.1 - 0.033 12.7 0.0 0.1 11.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1864) Amidohydro_2 PF04909.9 KFH44280.1 - 0.044 13.3 0.0 0.066 12.7 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase peroxidase PF00141.18 KFH44281.1 - 1.1e-86 290.1 0.0 3.7e-47 160.7 0.0 2.2 2 0 0 2 2 2 2 Peroxidase tRNA-synt_1 PF00133.17 KFH44282.1 - 1.3e-53 181.9 0.0 2.1e-30 105.3 0.0 6.1 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 KFH44282.1 - 3.7e-42 143.7 0.0 7.8e-42 142.6 0.0 1.6 1 1 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 KFH44282.1 - 1.5e-32 112.7 0.0 3.5e-23 81.8 0.0 4.3 4 1 0 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KFH44282.1 - 2.5e-11 43.5 0.0 4.7e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 KFH44282.1 - 0.019 14.1 0.0 3.3 6.7 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 KFH44282.1 - 0.15 10.8 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (R) Cyclin_N PF00134.18 KFH44283.1 - 2.1e-41 140.4 0.0 4.2e-41 139.4 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFH44283.1 - 6.6e-35 119.5 0.2 1.3e-34 118.5 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Pkinase PF00069.20 KFH44285.1 - 2e-05 23.9 0.0 3e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KFH44285.1 - 0.012 15.4 0.2 0.027 14.1 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 KFH44285.1 - 0.091 12.0 0.0 0.33 10.2 0.0 1.8 2 0 0 2 2 2 0 RIO1 family TFIIB PF00382.14 KFH44288.1 - 2.9e-30 103.8 0.7 7.8e-19 67.2 0.1 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 KFH44288.1 - 2.9e-21 75.4 3.0 4.6e-21 74.8 0.7 2.5 2 0 0 2 2 2 1 Brf1-like TBP-binding domain Cyclin_N PF00134.18 KFH44288.1 - 2.5e-06 27.0 0.3 0.012 15.1 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Noc2 PF03715.8 KFH44288.1 - 0.048 12.5 0.1 0.076 11.8 0.1 1.2 1 0 0 1 1 1 0 Noc2p family Sugar_tr PF00083.19 KFH44290.1 - 2.2e-72 244.0 21.9 2.6e-72 243.8 15.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH44290.1 - 6.9e-29 100.6 46.3 6.8e-25 87.5 13.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFH44290.1 - 1.3e-06 26.9 1.1 1.3e-06 26.9 0.8 2.3 2 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) ACT_3 PF10000.4 KFH44291.1 - 2.1e-20 72.2 0.0 3.7e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 ACT domain ACT_7 PF13840.1 KFH44291.1 - 1.1e-08 34.4 0.0 1.7e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 ACT domain Cerato-platanin PF07249.7 KFH44292.1 - 0.0002 21.3 0.0 0.00036 20.5 0.0 1.4 1 0 0 1 1 1 1 Cerato-platanin OTT_1508_deam PF14441.1 KFH44293.1 - 4.6e-07 29.7 0.0 9.5e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase zf-MYND PF01753.13 KFH44293.1 - 0.002 17.9 16.6 0.0041 16.9 11.5 1.6 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KFH44293.1 - 1.7 8.5 7.0 4.7 7.1 4.8 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DPPIV_N PF00930.16 KFH44294.1 - 3.3e-103 344.9 2.0 4.6e-103 344.5 1.4 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 KFH44294.1 - 3.3e-39 134.3 1.6 5.8e-39 133.5 1.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFH44294.1 - 1.2e-06 28.3 0.0 3e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFH44294.1 - 3.8e-06 26.9 0.2 1.8e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Mito_carr PF00153.22 KFH44296.1 - 2.1e-72 238.8 0.6 5e-25 87.0 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_8 PF13833.1 KFH44296.1 - 2.7e-15 55.7 0.5 0.0072 15.9 0.1 5.4 5 0 0 5 5 5 4 EF-hand domain pair EF-hand_6 PF13405.1 KFH44296.1 - 2.3e-13 48.8 0.2 4.2e-05 23.0 0.0 5.4 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.27 KFH44296.1 - 1.6e-12 45.7 5.7 1.1e-06 27.4 0.0 4.6 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.1 KFH44296.1 - 2.1e-12 46.9 1.4 1.6e-05 24.9 0.0 3.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KFH44296.1 - 1.1e-09 37.1 1.7 1.1e-05 24.4 0.0 3.8 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 KFH44296.1 - 0.026 14.4 0.1 11 6.0 0.0 3.8 4 0 0 4 4 4 0 EF-hand domain F_bP_aldolase PF01116.15 KFH44298.1 - 1.1e-85 287.2 0.3 1.2e-85 287.0 0.2 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II APH PF01636.18 KFH44299.1 - 7.4e-33 114.2 1.3 1.4e-32 113.3 0.9 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Peptidase_S24 PF00717.18 KFH44299.1 - 8.9e-06 25.2 0.1 1.8e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like Choline_kinase PF01633.15 KFH44299.1 - 0.0065 16.0 0.0 0.0099 15.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Indigoidine_A PF04227.7 KFH44300.1 - 0.067 12.4 2.1 0.096 11.8 1.5 1.3 1 0 0 1 1 1 0 Indigoidine synthase A like protein DUF4098 PF13345.1 KFH44300.1 - 0.19 11.7 1.8 2.4 8.1 1.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4098) DUF1349 PF07081.6 KFH44301.1 - 1.5e-18 66.8 0.1 2.2e-18 66.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) DUF2442 PF10387.4 KFH44301.1 - 0.13 12.3 0.1 0.3 11.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2442) VCBS PF13517.1 KFH44301.1 - 0.13 12.6 0.2 0.32 11.3 0.1 1.7 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Flocculin PF00624.13 KFH44301.1 - 0.87 9.4 6.0 1.7 8.5 1.5 2.4 2 0 0 2 2 2 0 Flocculin repeat AhpC-TSA_2 PF13911.1 KFH44302.1 - 2.3e-15 56.5 0.0 6.2e-15 55.1 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 KFH44302.1 - 5.5e-07 29.3 0.0 8.8e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KFH44302.1 - 1.8e-06 27.5 0.0 3.4e-06 26.6 0.0 1.3 1 1 0 1 1 1 1 Redoxin Kinesin PF00225.18 KFH44303.1 - 3.2e-56 190.4 0.0 7.5e-56 189.2 0.0 1.6 1 1 0 1 1 1 1 Kinesin motor domain Exonuc_VII_L PF02601.10 KFH44303.1 - 0.2 10.8 1.1 0.31 10.1 0.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Herpes_BLRF2 PF05812.7 KFH44303.1 - 1.2 8.9 5.7 0.46 10.3 0.2 2.4 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein Abhydrolase_6 PF12697.2 KFH44304.1 - 9.3e-22 78.0 0.3 9.3e-21 74.7 0.2 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH44304.1 - 5.3e-09 35.9 0.1 0.0025 17.5 0.0 2.8 3 0 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFH44304.1 - 1.9e-07 30.9 0.0 3.5e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold FA_hydroxylase PF04116.8 KFH44305.1 - 1.5e-06 28.5 1.2 1.5e-06 28.5 0.8 2.7 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily PSII_BNR PF14870.1 KFH44306.1 - 4e-08 32.6 4.9 8.8e-06 24.9 0.1 3.4 2 2 1 3 3 3 3 Photosynthesis system II assembly factor YCF48 BNR PF02012.15 KFH44306.1 - 3.9e-06 25.8 23.6 0.13 12.1 0.1 6.5 6 0 0 6 6 6 4 BNR/Asp-box repeat BNR_2 PF13088.1 KFH44306.1 - 0.00026 20.3 1.3 0.076 12.2 0.1 2.6 1 1 1 2 2 2 2 BNR repeat-like domain DSS1_SEM1 PF05160.8 KFH44307.1 - 2.2e-21 75.3 16.7 3.2e-21 74.8 11.6 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family Cwf_Cwc_15 PF04889.7 KFH44307.1 - 0.16 11.6 6.6 0.17 11.5 4.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Glycoamylase PF10091.4 KFH44308.1 - 0.018 14.1 0.0 0.041 12.9 0.0 1.6 2 0 0 2 2 2 0 Putative glucoamylase Zn_clus PF00172.13 KFH44309.1 - 0.00043 20.1 11.6 0.00083 19.2 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.5 KFH44309.1 - 0.005 16.0 0.5 0.06 12.5 0.0 2.4 2 0 0 2 2 2 1 Histone chaperone domain CHZ DUF1908 PF08926.6 KFH44309.1 - 0.073 11.8 0.7 0.14 10.8 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) FAM176 PF14851.1 KFH44310.1 - 0.013 15.2 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 FAM176 family Paf1 PF03985.8 KFH44310.1 - 0.12 11.0 1.8 0.17 10.6 1.3 1.1 1 0 0 1 1 1 0 Paf1 Nucleoplasmin PF03066.10 KFH44310.1 - 0.13 11.8 3.8 0.18 11.2 2.7 1.2 1 0 0 1 1 1 0 Nucleoplasmin Ctr PF04145.10 KFH44310.1 - 0.16 12.0 0.6 0.47 10.5 0.4 1.8 1 1 1 2 2 2 0 Ctr copper transporter family PBP1_TM PF14812.1 KFH44310.1 - 0.6 10.4 9.1 1.1 9.5 6.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_hydro_18 PF00704.23 KFH44311.1 - 2.2e-102 343.0 3.8 2.5e-102 342.8 2.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 SNARE PF05739.14 KFH44313.1 - 9.9e-14 50.7 3.9 9.9e-14 50.7 2.7 1.8 2 0 0 2 2 2 1 SNARE domain Fusion_gly PF00523.13 KFH44313.1 - 0.021 12.9 0.6 0.033 12.2 0.4 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 HXXSHH PF07586.6 KFH44313.1 - 0.036 12.9 1.3 0.15 10.9 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1552) Phage_GP20 PF06810.6 KFH44313.1 - 0.086 12.2 3.3 0.41 10.0 0.5 2.4 2 1 0 2 2 2 0 Phage minor structural protein GP20 Allexi_40kDa PF05549.6 KFH44313.1 - 0.11 11.8 0.1 0.11 11.8 0.1 1.9 2 0 0 2 2 2 0 Allexivirus 40kDa protein HOOK PF05622.7 KFH44313.1 - 0.14 9.9 8.2 0.23 9.2 0.1 2.0 2 0 0 2 2 2 0 HOOK protein FliJ PF02050.11 KFH44313.1 - 0.34 10.9 7.7 4.9 7.2 1.8 3.7 2 2 2 4 4 4 0 Flagellar FliJ protein DUF4164 PF13747.1 KFH44313.1 - 3.9 7.6 7.8 9.5 6.4 1.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) Trp_syntA PF00290.15 KFH44314.1 - 3.1e-94 314.3 0.0 5.3e-94 313.5 0.0 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 KFH44314.1 - 2.4e-45 155.0 0.8 4.3e-45 154.2 0.5 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme STN PF07660.9 KFH44314.1 - 0.14 11.7 0.2 22 4.6 0.0 2.6 2 0 0 2 2 2 0 Secretin and TonB N terminus short domain SWIM PF04434.12 KFH44315.1 - 8.5e-05 21.9 1.1 0.066 12.6 0.0 2.3 2 0 0 2 2 2 2 SWIM zinc finger Ribosom_S12_S23 PF00164.20 KFH44316.1 - 3.6e-41 139.4 0.4 4.1e-41 139.2 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 ICAP-1_inte_bdg PF10480.4 KFH44317.1 - 3 7.5 6.5 6.7 6.4 4.5 1.5 1 0 0 1 1 1 0 Beta-1 integrin binding protein Ribosomal_L28 PF00830.14 KFH44319.1 - 3.5e-17 61.9 0.7 7.3e-17 60.9 0.5 1.5 1 0 0 1 1 1 1 Ribosomal L28 family Atg8 PF02991.11 KFH44320.1 - 2.1e-51 172.2 0.2 2.4e-51 172.0 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 KFH44320.1 - 3.2e-06 27.2 0.0 3.9e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 ADK PF00406.17 KFH44321.1 - 3.4e-54 182.8 0.0 5.3e-54 182.1 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KFH44321.1 - 1.1e-14 53.7 0.0 2.9e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 KFH44321.1 - 5.8e-06 27.1 0.0 1.2e-05 26.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFH44321.1 - 0.00011 22.5 0.1 0.0051 17.1 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 KFH44321.1 - 0.00017 21.4 0.0 0.001 18.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFH44321.1 - 0.035 13.1 0.0 0.059 12.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF1741 PF08427.5 KFH44322.1 - 1.1e-85 286.9 0.0 2e-85 286.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) PrmA PF06325.8 KFH44323.1 - 7.4e-11 41.7 0.0 1.2e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 KFH44323.1 - 2.8e-10 40.5 0.0 6.9e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH44323.1 - 4.1e-10 39.4 0.0 6.9e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH44323.1 - 5.7e-10 39.7 0.0 1.2e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 KFH44323.1 - 1.6e-08 33.9 0.0 2.2e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_23 PF13489.1 KFH44323.1 - 1.2e-07 31.5 0.0 2.6e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFH44323.1 - 2.7e-07 30.6 0.0 4.7e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFH44323.1 - 1.5e-06 27.6 0.2 3.3e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KFH44323.1 - 6.4e-06 26.4 0.0 2.4e-05 24.6 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH44323.1 - 1.7e-05 25.1 0.0 5.1e-05 23.6 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Met_10 PF02475.11 KFH44323.1 - 0.00023 20.7 0.2 0.00039 20.0 0.1 1.2 1 0 0 1 1 1 1 Met-10+ like-protein CMAS PF02353.15 KFH44323.1 - 0.00032 19.8 0.0 0.00044 19.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.6 KFH44323.1 - 0.00041 19.1 0.0 0.00064 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.9 KFH44323.1 - 0.00063 18.9 1.4 0.0018 17.5 1.0 1.7 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_16 PF10294.4 KFH44323.1 - 0.00096 18.6 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 KFH44323.1 - 0.0083 16.1 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.14 KFH44323.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 KFH44323.1 - 0.013 14.6 0.1 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 KFH44323.1 - 0.03 13.3 0.0 0.05 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.12 KFH44323.1 - 0.049 12.6 0.0 0.083 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_24 PF13578.1 KFH44323.1 - 0.11 13.3 0.0 0.33 11.7 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 KFH44323.1 - 0.12 11.9 0.2 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.10 KFH44323.1 - 0.14 11.5 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Inhibitor_I9 PF05922.11 KFH44324.1 - 0.00065 20.2 0.1 0.00098 19.6 0.1 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF762 PF05555.6 KFH44324.1 - 0.019 14.1 0.0 0.021 14.0 0.0 1.0 1 0 0 1 1 1 0 Coxiella burnetii protein of unknown function (DUF762) Adipogenin PF15202.1 KFH44326.1 - 1.3 8.9 5.2 1.7 8.5 3.6 1.2 1 0 0 1 1 1 0 Adipogenin Troponin-I_N PF11636.3 KFH44326.1 - 2 8.1 5.6 5.9 6.6 3.9 1.8 1 1 0 1 1 1 0 Troponin I residues 1-32 UbiA PF01040.13 KFH44327.1 - 1.5e-30 106.2 20.3 1.9e-30 105.9 14.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family MFS_1 PF07690.11 KFH44328.1 - 2.4e-22 79.1 37.8 2.8e-19 69.0 19.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH44328.1 - 2.9e-16 59.0 23.7 6e-16 58.0 16.4 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter LacAB_rpiB PF02502.13 KFH44328.1 - 0.045 13.4 0.4 0.081 12.5 0.3 1.3 1 0 0 1 1 1 0 Ribose/Galactose Isomerase DUF3611 PF12263.3 KFH44328.1 - 0.25 10.7 5.3 0.26 10.6 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) DUF2183 PF09949.4 KFH44329.1 - 1.8e-29 101.6 0.0 3.1e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) DUF1992 PF09350.5 KFH44330.1 - 2.7e-24 84.7 0.6 7.1e-24 83.4 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) CCDC66 PF15236.1 KFH44330.1 - 1.7 8.2 8.5 13 5.3 6.1 2.3 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 66 Aminotran_3 PF00202.16 KFH44331.1 - 7.6e-87 291.3 0.1 9e-87 291.0 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III XRN_N PF03159.13 KFH44332.1 - 7.3e-108 359.4 0.0 1.6e-107 358.3 0.0 1.6 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.18 KFH44332.1 - 0.37 10.7 4.8 0.73 9.8 3.3 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF3357 PF11837.3 KFH44334.1 - 0.059 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Aminotran_1_2 PF00155.16 KFH44336.1 - 4e-88 295.8 0.0 4.9e-88 295.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Antibiotic_NAT PF02522.9 KFH44336.1 - 0.15 11.2 0.0 0.29 10.3 0.0 1.5 1 0 0 1 1 1 0 Aminoglycoside 3-N-acetyltransferase WD40 PF00400.27 KFH44337.1 - 3.8e-09 36.0 8.9 0.00044 20.0 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat Mo25 PF08569.6 KFH44338.1 - 2.5e-122 408.1 0.0 2.8e-122 407.9 0.0 1.0 1 0 0 1 1 1 1 Mo25-like RepA_N PF06970.6 KFH44338.1 - 0.072 12.8 0.2 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 Replication initiator protein A (RepA) N-terminus Sugar_tr PF00083.19 KFH44339.1 - 3.8e-77 259.7 19.6 4.7e-77 259.4 13.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH44339.1 - 1.8e-18 66.3 30.3 1e-15 57.3 16.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Acyl_transf_3 PF01757.17 KFH44339.1 - 1.3 7.7 26.0 0.0094 14.8 7.1 2.5 2 1 0 2 2 2 0 Acyltransferase family SWIB PF02201.13 KFH44340.1 - 7.5e-13 47.9 0.0 1.4e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain SAPS PF04499.10 KFH44341.1 - 0.18 10.3 1.3 0.31 9.6 0.9 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein His_Phos_2 PF00328.17 KFH44342.1 - 2.3e-06 27.1 0.0 2.3e-05 23.8 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) tRNA-synt_1 PF00133.17 KFH44343.1 - 1.7e-223 743.0 0.0 3.6e-223 741.9 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KFH44343.1 - 5.2e-26 91.2 0.0 1.4e-25 89.7 0.0 1.7 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KFH44343.1 - 3.1e-18 65.6 0.1 1.7e-07 30.2 0.0 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 KFH44343.1 - 0.011 14.8 0.0 0.031 13.4 0.0 1.7 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Pkinase PF00069.20 KFH44344.1 - 1.1e-65 221.3 0.0 1.5e-65 220.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH44344.1 - 3.1e-31 108.4 0.0 2.1e-30 105.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFH44344.1 - 0.00028 20.0 0.0 0.00045 19.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFH44344.1 - 0.004 16.9 0.1 0.011 15.5 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KFH44344.1 - 0.01 14.8 0.1 0.06 12.2 0.0 2.2 2 1 0 2 2 2 1 Kinase-like Baculo_PEP_C PF04513.7 KFH44345.1 - 0.019 14.7 0.1 0.55 10.0 0.0 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Gly_transf_sug PF04488.10 KFH44345.1 - 0.022 15.1 0.0 0.058 13.7 0.0 1.7 1 0 0 1 1 1 0 Glycosyltransferase sugar-binding region containing DXD motif Coprogen_oxidas PF01218.13 KFH44346.1 - 8.6e-134 444.7 0.1 1e-133 444.4 0.1 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase OPT PF03169.10 KFH44347.1 - 7e-146 487.2 27.2 8.8e-146 486.8 18.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MscL PF01741.13 KFH44347.1 - 4.6 7.3 9.3 15 5.7 0.0 3.8 5 0 0 5 5 5 0 Large-conductance mechanosensitive channel, MscL Sfi1 PF08457.5 KFH44348.1 - 3.2e-15 55.5 21.8 3.2e-15 55.5 15.1 3.0 2 1 1 3 3 3 3 Sfi1 spindle body protein MitMem_reg PF13012.1 KFH44349.1 - 6e-39 132.7 0.0 1.4e-38 131.4 0.0 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 KFH44349.1 - 3.1e-28 97.8 0.0 7.4e-28 96.5 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF1682 PF07946.9 KFH44349.1 - 2 7.1 8.6 3.1 6.5 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) AA_permease PF00324.16 KFH44350.1 - 1.8e-137 458.6 43.2 2e-137 458.3 29.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFH44350.1 - 6.7e-36 123.7 47.2 9.2e-36 123.2 32.7 1.1 1 0 0 1 1 1 1 Amino acid permease Rav1p_C PF12234.3 KFH44351.1 - 2.2e-245 815.6 0.1 6.8e-131 437.4 0.0 2.1 2 0 0 2 2 2 2 RAVE protein 1 C terminal HOOK PF05622.7 KFH44352.1 - 1.7e-11 42.6 49.7 1.7e-11 42.6 34.5 3.4 3 1 0 3 3 3 3 HOOK protein CH PF00307.26 KFH44352.1 - 0.0046 16.9 0.1 0.021 14.8 0.0 2.1 2 0 0 2 2 2 1 Calponin homology (CH) domain DNA_pol_B_palm PF14792.1 KFH44352.1 - 1.5 8.9 6.1 23 5.0 0.1 4.0 3 1 0 3 3 3 0 DNA polymerase beta palm DUF2638 PF10937.3 KFH44353.1 - 2.1e-35 122.1 1.0 2.7e-35 121.7 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) RasGAP PF00616.14 KFH44354.1 - 3.9e-45 153.9 0.0 7.5e-45 153.0 0.0 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase JmjC PF02373.17 KFH44356.1 - 1.9e-09 37.7 0.0 5.5e-09 36.2 0.0 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 KFH44356.1 - 8.8e-06 25.8 11.4 8.8e-06 25.8 7.9 2.8 3 0 0 3 3 3 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 KFH44356.1 - 0.017 14.6 0.0 0.038 13.4 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Fungal_trans PF04082.13 KFH44357.1 - 1.1e-13 50.7 0.0 1.7e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH44357.1 - 0.00014 21.7 9.8 0.00023 20.9 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Uso1_p115_head PF04869.9 KFH44358.1 - 8.4e-102 340.1 0.0 1.6e-101 339.2 0.0 1.5 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 KFH44358.1 - 1e-10 41.6 28.0 1e-10 41.6 19.4 3.9 1 1 2 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4200 PF13863.1 KFH44358.1 - 0.0018 18.2 20.3 0.0018 18.2 14.1 4.2 2 1 3 5 5 5 1 Domain of unknown function (DUF4200) Filament PF00038.16 KFH44358.1 - 0.074 12.5 56.1 0.011 15.1 33.0 2.3 1 1 1 2 2 2 0 Intermediate filament protein HEAT PF02985.17 KFH44358.1 - 0.27 11.4 2.2 13 6.2 0.0 3.7 4 0 0 4 4 4 0 HEAT repeat Baculo_PEP_C PF04513.7 KFH44358.1 - 3.5 7.4 20.9 0.28 11.0 3.3 4.4 2 1 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus PPTA PF01239.17 KFH44360.1 - 1.9e-39 131.3 13.5 1.7e-08 33.4 0.0 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat ketoacyl-synt PF00109.21 KFH44362.1 - 1.3e-66 224.6 0.0 6.5e-66 222.4 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KFH44362.1 - 3e-35 122.0 0.0 6.1e-35 121.0 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KFH44362.1 - 1e-33 115.6 0.0 2.1e-33 114.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 KFH44362.1 - 1.6e-23 82.9 0.0 3.1e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.7 KFH44362.1 - 4.5e-15 55.9 0.0 1.7e-14 54.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH44362.1 - 1.6e-10 40.9 0.0 7.2e-10 38.8 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH44362.1 - 1.6e-07 31.6 0.0 3.6e-06 27.3 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH44362.1 - 2.1e-07 30.6 0.0 4.8e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KFH44362.1 - 5.4e-07 29.7 0.9 1.3e-06 28.5 0.6 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 KFH44362.1 - 0.00014 21.4 0.0 0.00077 18.9 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_18 PF12847.2 KFH44362.1 - 0.00052 20.5 0.0 0.0079 16.7 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain adh_short PF00106.20 KFH44362.1 - 0.0013 18.6 0.0 0.0036 17.2 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase RrnaAD PF00398.15 KFH44362.1 - 0.002 17.1 0.0 0.004 16.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Thiolase_N PF00108.18 KFH44362.1 - 0.0027 16.7 0.0 0.0062 15.5 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_26 PF13659.1 KFH44362.1 - 0.0049 16.8 0.0 0.016 15.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ACP_syn_III PF08545.5 KFH44362.1 - 0.0055 16.3 0.2 0.019 14.5 0.2 2.0 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III NodS PF05401.6 KFH44362.1 - 0.044 13.1 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 Nodulation protein S (NodS) 3Beta_HSD PF01073.14 KFH44362.1 - 0.092 11.4 0.0 0.86 8.2 0.0 2.2 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KFH44362.1 - 0.11 11.3 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 4HBT PF03061.17 KFH44363.1 - 7.9e-06 25.9 0.0 1.2e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Abhydrolase_3 PF07859.8 KFH44364.1 - 0.0012 18.5 0.0 0.0032 17.0 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF459 PF04311.8 KFH44364.1 - 0.1 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF459) Pox_RNA_pol PF03293.9 KFH44364.1 - 0.14 11.6 0.1 0.3 10.5 0.1 1.5 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Pyr_redox_2 PF07992.9 KFH44365.1 - 1e-24 87.5 1.8 1.7e-24 86.8 1.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFH44365.1 - 1.3e-10 41.4 7.0 2.2e-10 40.7 1.8 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 KFH44365.1 - 1.6e-08 34.0 0.0 1.3e-07 31.1 0.0 2.3 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 KFH44365.1 - 8.8e-07 29.1 0.0 0.00014 22.0 0.0 3.1 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 KFH44365.1 - 1.2e-06 28.7 0.1 3.5e-06 27.2 0.1 1.8 1 0 0 1 1 1 1 Reductase C-terminal NAD_binding_9 PF13454.1 KFH44365.1 - 0.00088 19.0 0.3 3.6 7.3 0.0 3.3 2 1 1 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 KFH44365.1 - 0.0014 17.6 0.1 1.4 7.7 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DUF2767 PF10965.3 KFH44365.1 - 0.045 13.5 0.2 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2767) NAD_binding_7 PF13241.1 KFH44365.1 - 0.07 13.4 0.9 2.6 8.3 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Hydrolase_6 PF13344.1 KFH44366.1 - 5.1e-15 55.1 0.0 8.4e-15 54.5 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFH44366.1 - 0.001 19.5 0.0 0.0034 17.8 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KFH44366.1 - 0.0057 16.9 1.3 0.076 13.2 0.0 2.5 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFH44366.1 - 0.0065 16.1 0.0 0.056 13.1 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_3 PF08282.7 KFH44366.1 - 0.012 15.1 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Glyco_hydro_2 PF00703.16 KFH44367.1 - 4.6e-10 39.9 0.0 1.8e-09 37.9 0.0 2.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 KFH44367.1 - 3.8e-08 33.0 0.0 8.4e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain AATase PF07247.7 KFH44368.1 - 2.8e-15 55.8 0.0 1.5e-12 46.8 0.0 2.1 2 0 0 2 2 2 2 Alcohol acetyltransferase Condensation PF00668.15 KFH44368.1 - 0.014 14.2 0.0 0.11 11.3 0.0 1.9 1 1 0 1 1 1 0 Condensation domain BTG PF07742.7 KFH44368.1 - 0.074 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 BTG family Acyl_transf_3 PF01757.17 KFH44369.1 - 2e-19 69.6 21.5 2e-19 69.6 14.9 1.5 1 1 1 2 2 2 1 Acyltransferase family ATP-synt_ab_N PF02874.18 KFH44370.1 - 0.038 14.2 0.0 0.077 13.2 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, beta-barrel domain DNA_pol_alpha_N PF12254.3 KFH44370.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal Glyco_hydro_1 PF00232.13 KFH44371.1 - 1.2e-74 251.1 0.5 1.3e-72 244.4 0.3 2.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Sec3_C PF09763.4 KFH44372.1 - 0.09 10.8 14.1 0.15 10.1 9.7 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec3 DivIVA PF05103.8 KFH44372.1 - 0.44 10.5 30.2 2.4 8.2 0.0 4.0 3 1 1 4 4 4 0 DivIVA protein IncA PF04156.9 KFH44372.1 - 9.1 5.8 39.3 1.9 8.0 9.1 3.4 1 1 1 3 3 3 0 IncA protein DEAD PF00270.24 KFH44373.1 - 1e-46 158.5 0.0 5.8e-45 152.8 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFH44373.1 - 2.5e-28 97.7 0.0 2e-27 94.8 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 KFH44373.1 - 0.0021 16.5 0.0 0.0021 16.5 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1253) MIP-T3 PF10243.4 KFH44373.1 - 0.41 9.0 40.8 0.56 8.6 28.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1675 PF07897.6 KFH44373.1 - 4.9 6.9 20.2 8.4 6.1 14.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) adh_short PF00106.20 KFH44374.1 - 5e-11 42.8 0.2 6.1e-11 42.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KFH44374.1 - 2.2e-06 27.7 0.7 1.7e-05 24.8 0.5 1.9 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KFH44374.1 - 0.0033 17.0 0.2 0.0044 16.7 0.1 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KFH44374.1 - 0.089 11.9 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) FAD_binding_4 PF01565.18 KFH44377.1 - 7.4e-17 61.1 1.9 4e-16 58.7 1.7 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KFH44377.1 - 2.1e-10 40.3 0.1 5.4e-10 39.0 0.1 1.8 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.5 KFH44377.1 - 0.065 12.3 0.0 0.098 11.7 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding PseudoU_synth_2 PF00849.17 KFH44378.1 - 2.1e-29 102.4 0.0 3e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 KFH44378.1 - 0.012 14.9 0.2 0.027 13.8 0.1 1.5 1 0 0 1 1 1 0 S4 domain Ub-Mut7C PF14451.1 KFH44378.1 - 0.097 12.2 0.0 0.27 10.7 0.0 1.7 1 0 0 1 1 1 0 Mut7-C ubiquitin Auto_anti-p27 PF06677.7 KFH44378.1 - 0.18 11.5 0.1 0.44 10.3 0.1 1.6 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) ATP-grasp_2 PF08442.5 KFH44379.1 - 1.9e-45 154.7 0.2 1.6e-38 132.1 0.0 2.2 1 1 1 2 2 2 2 ATP-grasp domain Ligase_CoA PF00549.14 KFH44379.1 - 7.5e-16 58.0 1.6 7.5e-16 58.0 1.1 2.1 2 2 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.1 KFH44379.1 - 0.015 14.4 0.2 0.24 10.6 0.0 2.6 2 1 0 2 2 2 0 ATP-grasp domain FAD_binding_4 PF01565.18 KFH44380.1 - 1.1e-33 115.6 4.4 2.8e-33 114.3 3.1 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFH44380.1 - 2.1e-08 33.9 0.1 3.8e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 Berberine and berberine like Melibiase PF02065.13 KFH44382.1 - 4.3e-161 536.0 0.0 5.4e-161 535.6 0.0 1.1 1 0 0 1 1 1 1 Melibiase DUF187 PF02638.10 KFH44382.1 - 0.027 13.3 0.0 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase like GH101 GFO_IDH_MocA PF01408.17 KFH44383.1 - 8.2e-16 58.6 0.0 1.8e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KFH44383.1 - 0.00063 19.5 0.2 0.0012 18.5 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain adh_short PF00106.20 KFH44384.1 - 2.4e-25 89.3 0.8 2.4e-25 89.3 0.6 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH44384.1 - 1.2e-09 38.2 0.2 1.6e-09 37.9 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH44384.1 - 1.7e-08 34.3 1.0 3.7e-08 33.2 0.7 1.5 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 KFH44384.1 - 5.7e-05 21.9 0.4 8.1e-05 21.4 0.3 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KFH44384.1 - 0.00084 19.3 0.6 0.0022 18.0 0.4 1.6 1 1 0 1 1 1 1 NADH(P)-binding 2-Hacid_dh_C PF02826.14 KFH44384.1 - 0.069 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.16 KFH44384.1 - 0.074 12.4 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.11 KFH44385.1 - 1.2e-38 132.7 43.2 1.2e-38 132.7 30.0 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH44385.1 - 0.21 10.1 33.8 2.8 6.4 22.9 2.7 1 1 1 2 2 2 0 Sugar (and other) transporter Glyco_tranf_2_3 PF13641.1 KFH44386.1 - 3.1e-17 63.1 0.1 5e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KFH44386.1 - 2.6e-05 23.9 0.0 5.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KFH44386.1 - 0.00024 20.4 0.2 0.13 11.5 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glyco_hydro_88 PF07470.8 KFH44387.1 - 1.7e-71 241.0 3.0 2.2e-71 240.6 2.1 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Fungal_trans_2 PF11951.3 KFH44388.1 - 0.019 13.5 0.0 0.034 12.7 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain Fungal_trans_2 PF11951.3 KFH44389.1 - 7.5e-06 24.7 0.2 3e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain STIL_N PF15253.1 KFH44389.1 - 0.22 10.1 0.1 0.36 9.4 0.1 1.2 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus FSH1 PF03959.8 KFH44390.1 - 8.8e-28 97.1 0.0 1.1e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KFH44390.1 - 0.01 15.5 0.1 0.024 14.4 0.1 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KFH44390.1 - 0.026 13.9 0.0 0.073 12.4 0.0 1.8 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 KFH44390.1 - 0.08 12.5 0.3 0.18 11.3 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold RGS PF00615.14 KFH44391.1 - 2.4e-07 30.8 0.0 2.3e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain FAD_binding_3 PF01494.14 KFH44392.1 - 6.1e-17 61.7 8.9 4.4e-11 42.4 0.1 3.1 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KFH44392.1 - 2.6e-05 24.1 0.6 8.1e-05 22.5 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFH44392.1 - 0.0002 20.4 0.5 0.0002 20.4 0.4 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KFH44392.1 - 0.011 15.5 0.4 0.033 13.9 0.3 1.9 1 1 0 1 1 1 0 FAD-NAD(P)-binding SE PF08491.5 KFH44392.1 - 0.02 13.7 0.0 0.081 11.7 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox PF00070.22 KFH44392.1 - 0.036 14.4 0.5 0.036 14.4 0.3 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFH44392.1 - 0.056 13.4 3.2 0.13 12.2 0.5 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFH44392.1 - 0.068 13.0 0.3 0.25 11.1 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mac PF12464.3 KFH44393.1 - 1.8e-21 75.8 0.1 2.8e-21 75.2 0.1 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.19 KFH44393.1 - 1.7e-14 52.5 10.2 6.3e-13 47.6 3.1 3.8 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KFH44393.1 - 3.8e-14 51.9 8.3 2.1e-13 49.5 2.2 3.2 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Fungal_trans PF04082.13 KFH44394.1 - 3.9e-16 58.7 0.1 6.8e-16 57.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2706 PF10913.3 KFH44394.1 - 0.03 13.9 0.1 0.1 12.2 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2706) Herpes_capsid PF06112.6 KFH44394.1 - 1.3 9.1 6.7 3 7.8 4.6 1.6 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Pyr_redox_3 PF13738.1 KFH44395.1 - 2.3e-23 83.3 0.0 3.3e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFH44395.1 - 1.2e-09 38.0 0.0 3.3e-08 33.4 0.0 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 KFH44395.1 - 2e-09 36.2 0.0 9.5e-09 33.9 0.0 1.9 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KFH44395.1 - 4.1e-07 29.2 0.0 2.7e-05 23.2 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KFH44395.1 - 6.7e-07 28.5 0.1 1.6e-05 23.9 0.1 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFH44395.1 - 4.4e-06 26.9 0.0 0.14 12.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFH44395.1 - 1.9e-05 23.8 0.0 0.0008 18.5 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 KFH44395.1 - 5.1e-05 23.2 0.0 0.0021 17.9 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KFH44395.1 - 0.00018 20.7 0.0 0.0063 15.6 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 KFH44395.1 - 0.0015 17.7 0.0 0.043 12.8 0.0 2.4 2 0 0 2 2 2 1 FAD binding domain Mqo PF06039.10 KFH44395.1 - 0.0042 15.3 0.0 0.22 9.6 0.0 2.4 2 1 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) FAD_binding_2 PF00890.19 KFH44395.1 - 0.0098 14.7 0.0 0.65 8.7 0.0 2.6 3 0 0 3 3 3 1 FAD binding domain Shikimate_DH PF01488.15 KFH44395.1 - 0.019 15.0 0.0 3.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 KFH44395.1 - 0.063 13.0 0.1 1.8 8.2 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KFH44395.1 - 0.15 10.9 0.0 2.4 6.9 0.0 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein ketoacyl-synt PF00109.21 KFH44396.1 - 8.8e-68 228.5 0.3 4.8e-67 226.1 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KFH44396.1 - 1.3e-55 187.8 0.9 3.5e-55 186.4 0.6 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 KFH44396.1 - 1.7e-53 181.7 0.4 4e-53 180.5 0.3 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KFH44396.1 - 4e-49 167.6 0.5 8.1e-49 166.6 0.4 1.5 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 KFH44396.1 - 3.8e-46 157.0 2.7 8.4e-46 155.9 0.6 2.7 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KFH44396.1 - 9.7e-38 128.6 0.8 4.1e-37 126.6 0.0 2.6 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KFH44396.1 - 1.2e-16 60.4 0.0 9.1e-15 54.3 0.0 3.4 3 1 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KFH44396.1 - 3.1e-11 43.6 0.0 1.8e-10 41.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH44396.1 - 1.3e-09 37.9 0.0 3.1e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH44396.1 - 1.5e-06 28.5 0.0 0.00013 22.4 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH44396.1 - 8.2e-06 26.3 0.0 6.1e-05 23.5 0.0 2.6 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KFH44396.1 - 1.2e-05 25.5 0.7 3.5e-05 23.9 0.5 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KFH44396.1 - 3.8e-05 22.8 0.1 9.6e-05 21.4 0.0 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_26 PF13659.1 KFH44396.1 - 0.00047 20.1 0.1 0.0028 17.6 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH44396.1 - 0.00062 19.3 0.0 0.0014 18.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Shikimate_DH PF01488.15 KFH44396.1 - 0.075 13.1 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Methyltransf_16 PF10294.4 KFH44396.1 - 0.21 11.0 0.0 1.5 8.2 0.0 2.3 2 1 0 2 2 2 0 Putative methyltransferase ADH_N PF08240.7 KFH44396.1 - 0.22 11.3 0.0 0.73 9.6 0.0 1.8 2 0 0 2 2 1 0 Alcohol dehydrogenase GroES-like domain Polysacc_synt_2 PF02719.10 KFH44396.1 - 0.26 10.1 0.0 0.54 9.1 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein CoA_binding PF02629.14 KFH44397.1 - 5.6e-22 78.0 1.0 5.6e-22 78.0 0.7 2.2 2 1 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 KFH44397.1 - 2.5e-18 66.1 1.6 5.6e-18 64.9 1.1 1.6 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 KFH44397.1 - 4.4e-09 36.0 0.2 9.9e-09 34.9 0.1 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain DUF2122 PF09895.4 KFH44397.1 - 0.061 13.5 0.1 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 RecB-family nuclease (DUF2122) Fungal_trans PF04082.13 KFH44399.1 - 6.5e-21 74.3 0.0 9.6e-21 73.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH44399.1 - 4.7e-08 32.7 8.2 8.9e-08 31.9 5.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-UDP PF14569.1 KFH44399.1 - 1.9 8.3 4.6 2.4 7.9 0.9 2.3 2 0 0 2 2 2 0 Zinc-binding RING-finger ATP1G1_PLM_MAT8 PF02038.11 KFH44400.1 - 0.32 10.0 3.6 0.95 8.5 0.1 2.5 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family DUF2909 PF11137.3 KFH44400.1 - 0.35 10.6 6.0 0.14 11.9 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2909) DUF4064 PF13273.1 KFH44400.1 - 8 6.6 9.4 1.4e+03 -0.6 5.9 3.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Fungal_trans PF04082.13 KFH44401.1 - 1.5e-15 56.8 0.0 4.8e-15 55.1 0.0 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH44401.1 - 1.3e-08 34.6 10.0 2.2e-08 33.8 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clusterin PF01093.12 KFH44401.1 - 2 7.1 3.4 2.9 6.6 2.3 1.1 1 0 0 1 1 1 0 Clusterin Sulfatase PF00884.18 KFH44402.1 - 7.3e-14 51.6 0.5 3.5e-13 49.4 0.4 2.0 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KFH44402.1 - 8.9e-05 21.9 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KFH44402.1 - 0.04 12.3 0.0 0.058 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Acetyltransf_1 PF00583.19 KFH44403.1 - 5.2e-08 32.8 0.0 7.5e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFH44403.1 - 1.2e-06 28.5 0.0 2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFH44403.1 - 1.5e-05 25.1 0.2 1.9e-05 24.7 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KFH44403.1 - 0.029 14.3 0.0 0.042 13.7 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain NUDIX PF00293.23 KFH44404.1 - 2.7e-11 43.2 0.2 4e-11 42.6 0.1 1.3 1 1 0 1 1 1 1 NUDIX domain Rft-1 PF04506.8 KFH44405.1 - 3.7e-93 312.7 3.9 4.3e-93 312.5 2.7 1.0 1 0 0 1 1 1 1 Rft protein Pro_CA PF00484.14 KFH44406.1 - 4.7e-25 88.3 0.0 7.2e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 Carbonic anhydrase MFS_1 PF07690.11 KFH44407.1 - 1e-27 96.7 58.2 1.3e-21 76.6 23.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KFH44407.1 - 0.12 12.3 11.8 0.47 10.4 0.7 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1228) Ldr_toxin PF13940.1 KFH44407.1 - 0.22 11.3 2.8 0.35 10.6 0.5 2.4 2 0 0 2 2 2 0 Toxin Ldr, type I toxin-antitoxin system DUF3591 PF12157.3 KFH44409.1 - 3.2e-181 602.7 0.4 3.2e-181 602.7 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.18 KFH44409.1 - 0.014 15.3 0.9 0.029 14.3 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.1 KFH44409.1 - 0.019 14.6 0.4 0.019 14.6 0.3 1.9 2 0 0 2 2 2 0 Zinc knuckle DUF3844 PF12955.2 KFH44410.1 - 1.5e-32 111.7 3.0 2.4e-32 111.0 2.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.8 KFH44410.1 - 0.025 14.7 9.8 0.068 13.3 6.8 1.8 1 1 0 1 1 1 0 EGF-like domain EGF_3 PF12947.2 KFH44410.1 - 1.4 8.9 9.0 3.3 7.7 6.2 1.6 1 0 0 1 1 1 0 EGF domain ANTH PF07651.11 KFH44411.1 - 3.7e-67 225.9 0.5 8.1e-67 224.8 0.1 1.7 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.15 KFH44411.1 - 5.7e-07 29.4 0.0 2e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 ENTH domain Ribosomal_S13_N PF08069.7 KFH44411.1 - 0.17 11.7 1.1 12 5.7 0.0 3.5 3 0 0 3 3 3 0 Ribosomal S13/S15 N-terminal domain Mito_carr PF00153.22 KFH44412.1 - 9.8e-44 146.9 0.3 1.2e-21 76.2 0.0 2.7 2 1 0 2 2 2 2 Mitochondrial carrier protein F-box-like PF12937.2 KFH44413.1 - 4.5e-11 42.2 0.3 1e-10 41.1 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFH44413.1 - 0.00081 18.9 0.8 0.0018 17.8 0.5 1.6 1 0 0 1 1 1 1 F-box domain Zip PF02535.17 KFH44413.1 - 0.0014 17.7 0.4 0.0015 17.6 0.3 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Innate_immun PF12782.2 KFH44413.1 - 0.089 11.9 6.4 0.17 11.0 4.5 1.4 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family CS PF04969.11 KFH44414.1 - 4e-14 52.9 0.0 7.8e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 CS domain Rhodanese PF00581.15 KFH44415.1 - 3.9e-30 104.5 0.0 2.3e-08 34.3 0.0 4.8 4 2 0 4 4 4 4 Rhodanese-like domain Pyr_redox_3 PF13738.1 KFH44416.1 - 5.5e-26 91.9 0.0 8.6e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFH44416.1 - 1.3e-12 46.6 0.0 2.8e-12 45.6 0.0 1.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KFH44416.1 - 6.3e-09 35.7 0.0 1.3e-07 31.5 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KFH44416.1 - 1.7e-08 33.7 0.0 3.4e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KFH44416.1 - 2.3e-08 33.3 0.0 0.0047 15.8 0.0 3.5 3 1 1 4 4 4 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KFH44416.1 - 2e-05 23.8 0.0 0.005 15.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.22 KFH44416.1 - 0.0012 19.1 0.1 0.9 9.9 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFH44416.1 - 0.0036 16.4 0.0 0.027 13.5 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 KFH44416.1 - 0.0067 15.3 0.0 0.12 11.2 0.0 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 KFH44416.1 - 0.013 15.2 0.6 1.5 8.5 0.0 3.1 4 0 0 4 4 4 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KFH44416.1 - 0.029 13.2 0.0 0.067 12.0 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.15 KFH44416.1 - 0.045 13.8 0.0 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.2 KFH44416.1 - 0.067 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Malic_M PF03949.10 KFH44416.1 - 0.14 11.6 0.0 16 4.9 0.0 2.5 2 1 0 2 2 2 0 Malic enzyme, NAD binding domain Pyr_redox_2 PF07992.9 KFH44416.1 - 0.16 11.8 0.0 0.74 9.6 0.0 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFH44416.1 - 0.18 10.2 0.0 2.2 6.6 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Glyco_hydro_3 PF00933.16 KFH44417.1 - 1.6e-69 234.1 0.0 2.9e-69 233.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KFH44417.1 - 2.3e-41 141.8 0.1 1.9e-40 138.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KFH44417.1 - 3.5e-26 90.9 0.2 6.7e-26 90.0 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Utp11 PF03998.8 KFH44418.1 - 6.2e-54 183.3 18.1 7.8e-54 183.0 12.5 1.1 1 0 0 1 1 1 1 Utp11 protein FRG1 PF06229.7 KFH44419.1 - 1.1e-57 194.5 0.0 1.5e-57 194.1 0.0 1.2 1 0 0 1 1 1 1 FRG1-like family Fascin PF06268.8 KFH44419.1 - 0.0025 17.8 0.0 0.0056 16.7 0.0 1.7 1 0 0 1 1 1 1 Fascin domain GNVR PF13807.1 KFH44420.1 - 0.0025 17.5 0.0 0.0061 16.2 0.0 1.6 1 0 0 1 1 1 1 G-rich domain on putative tyrosine kinase DUF948 PF06103.6 KFH44421.1 - 0.13 12.0 0.1 0.89 9.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) zf-DHHC PF01529.15 KFH44421.1 - 1.3 8.3 7.0 1.4e+02 1.7 4.9 2.5 1 1 0 1 1 1 0 DHHC palmitoyltransferase Cmc1 PF08583.5 KFH44422.1 - 1.5e-16 59.9 2.3 1.5e-16 59.9 1.6 1.7 3 0 0 3 3 3 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 KFH44422.1 - 0.021 14.7 0.6 5.6 7.0 0.0 2.4 2 0 0 2 2 2 0 CHCH domain NR_Repeat PF14046.1 KFH44422.1 - 1.5 8.6 3.8 15 5.3 0.2 2.9 2 1 1 3 3 3 0 Nuclear receptor repeat ADH_N PF08240.7 KFH44423.1 - 1.3e-30 105.3 1.5 1.5e-30 105.1 0.2 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFH44423.1 - 8.1e-25 86.8 0.5 1.5e-24 86.0 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFH44423.1 - 9.2e-07 29.8 0.2 2.6e-06 28.3 0.1 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 KFH44423.1 - 0.0025 18.3 0.1 0.0058 17.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Pyr_redox PF00070.22 KFH44423.1 - 0.0075 16.6 0.1 0.25 11.7 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFH44423.1 - 0.012 14.1 0.4 0.019 13.4 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.9 KFH44423.1 - 0.02 14.2 0.1 0.032 13.6 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 KFH44423.1 - 0.071 12.7 0.6 0.12 11.9 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thiolase_N PF00108.18 KFH44424.1 - 1.4e-95 319.2 0.0 2.1e-95 318.6 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KFH44424.1 - 6.1e-46 154.8 0.5 6.5e-45 151.5 0.2 2.2 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KFH44424.1 - 2.3e-06 27.2 2.0 0.00013 21.5 0.6 2.6 1 1 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain LSM PF01423.17 KFH44425.1 - 2.6e-19 68.5 0.6 2.9e-19 68.3 0.4 1.0 1 0 0 1 1 1 1 LSM domain Pex2_Pex12 PF04757.9 KFH44426.1 - 2.4e-41 141.6 1.4 3.6e-41 141.0 1.0 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 KFH44426.1 - 0.00044 20.0 4.0 0.00093 19.0 2.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KFH44426.1 - 0.01 15.4 1.2 0.024 14.3 0.8 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFH44426.1 - 0.012 15.3 1.2 0.067 12.9 0.1 2.2 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 KFH44426.1 - 0.033 14.2 9.1 0.037 14.0 2.8 2.6 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFH44426.1 - 1.2 8.9 7.3 9.5 5.9 3.0 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFH44426.1 - 1.9 8.4 8.7 24 4.8 0.1 2.6 2 1 0 2 2 2 0 Ring finger domain Sulfotransfer_3 PF13469.1 KFH44427.1 - 8e-05 23.6 4.4 0.00018 22.4 0.2 2.1 1 1 1 2 2 2 1 Sulfotransferase family Sugar_tr PF00083.19 KFH44428.1 - 1.2e-123 413.0 22.4 1.4e-123 412.8 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH44428.1 - 9.7e-22 77.1 33.2 3.4e-15 55.6 6.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Zip PF02535.17 KFH44429.1 - 1.5e-53 181.8 0.8 1.9e-53 181.5 0.6 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Sdh_cyt PF01127.17 KFH44429.1 - 0.066 13.0 0.2 0.066 13.0 0.1 3.0 3 1 0 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit IMS_C PF11799.3 KFH44430.1 - 0.032 14.1 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 impB/mucB/samB family C-terminal domain Fungal_trans PF04082.13 KFH44431.1 - 4.2e-13 48.7 0.0 6e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH44431.1 - 1.6e-06 27.9 9.9 1.6e-06 27.9 6.9 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1446 PF07287.6 KFH44432.1 - 1.2e-109 366.0 0.0 1.6e-109 365.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) IQ PF00612.22 KFH44433.1 - 0.0001 21.5 0.2 0.00029 20.1 0.1 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Aldolase_II PF00596.16 KFH44434.1 - 7.4e-41 139.7 2.5 1e-40 139.3 1.7 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Peptidase_M1 PF01433.15 KFH44435.1 - 9.7e-13 47.9 0.0 0.00046 19.3 0.0 3.3 3 0 0 3 3 3 3 Peptidase family M1 HEAT_2 PF13646.1 KFH44435.1 - 0.002 18.3 0.0 0.15 12.3 0.0 3.3 3 0 0 3 3 3 1 HEAT repeats D-ser_dehydrat PF14031.1 KFH44437.1 - 3.4e-21 75.2 0.0 8.8e-21 73.9 0.0 1.7 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 KFH44437.1 - 2e-09 37.3 0.0 3.8e-09 36.4 0.0 1.4 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain PQ-loop PF04193.9 KFH44438.1 - 7.1e-27 92.7 2.2 4.7e-18 64.4 0.1 2.7 2 1 0 2 2 2 2 PQ loop repeat Cation_efflux PF01545.16 KFH44438.1 - 0.043 12.8 2.1 0.054 12.5 1.4 1.1 1 0 0 1 1 1 0 Cation efflux family Herpes_UL43 PF05072.8 KFH44438.1 - 0.098 11.3 1.5 2.8 6.6 0.1 2.1 1 1 1 2 2 2 0 Herpesvirus UL43 protein OTT_1508_deam PF14441.1 KFH44439.1 - 2.7e-24 85.6 0.0 4.6e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 OTT_1508-like deaminase SRF-TF PF00319.13 KFH44440.1 - 8.1e-23 79.4 0.1 1.2e-22 78.8 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) FAD_binding_2 PF00890.19 KFH44441.1 - 1.2e-85 287.9 1.0 1.5e-85 287.6 0.7 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 KFH44441.1 - 5.9e-22 77.2 0.7 5.8e-20 70.8 0.0 3.3 4 0 0 4 4 4 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 KFH44441.1 - 8.1e-14 51.2 2.8 5.5e-13 48.5 1.9 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KFH44441.1 - 2.8e-10 39.8 0.5 1.1e-09 37.9 0.3 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFH44441.1 - 1.5e-09 37.6 4.0 6.4e-08 32.5 0.4 3.6 2 1 2 4 4 4 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFH44441.1 - 3.2e-08 33.6 0.0 3.3e-06 27.1 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFH44441.1 - 2e-06 26.5 1.5 0.0051 15.3 0.2 3.3 3 0 0 3 3 3 2 HI0933-like protein Thi4 PF01946.12 KFH44441.1 - 8.1e-05 21.8 1.2 0.018 14.1 0.2 2.6 2 0 0 2 2 2 2 Thi4 family Amino_oxidase PF01593.19 KFH44441.1 - 0.00013 21.1 0.9 0.063 12.3 0.1 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 KFH44441.1 - 0.00046 19.9 0.2 0.0026 17.5 0.1 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KFH44441.1 - 0.00094 18.3 3.2 0.0034 16.4 2.2 1.8 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.17 KFH44441.1 - 0.0017 17.3 2.7 0.17 10.7 1.0 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox PF00070.22 KFH44441.1 - 0.016 15.5 2.4 0.2 12.0 0.3 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFH44441.1 - 0.14 12.2 1.8 0.3 11.1 0.6 2.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MAT1 PF06391.8 KFH44442.1 - 2.4e-27 95.8 6.6 3.4e-27 95.3 4.5 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 KFH44442.1 - 0.00012 21.6 6.3 0.00033 20.2 4.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFH44442.1 - 0.00017 21.2 8.2 0.00033 20.2 5.7 1.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFH44442.1 - 0.0014 18.5 8.8 0.004 17.1 6.2 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) MRP-S26 PF14943.1 KFH44442.1 - 0.018 14.6 11.1 0.029 13.9 7.7 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 zf-RING_2 PF13639.1 KFH44442.1 - 0.022 14.5 8.9 0.07 12.9 6.3 1.8 1 1 1 2 2 2 0 Ring finger domain zf-RING_5 PF14634.1 KFH44442.1 - 0.097 12.4 11.0 0.91 9.3 7.8 2.1 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.1 KFH44442.1 - 0.12 12.0 12.8 4.1 7.0 9.2 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.1 KFH44442.1 - 0.61 9.8 8.5 3.7 7.3 5.9 2.1 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_4 PF15227.1 KFH44442.1 - 0.62 9.9 3.9 1.5 8.7 2.7 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING APG6 PF04111.7 KFH44445.1 - 2.2 7.2 8.4 3.5 6.5 5.7 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 tRNA-synt_2 PF00152.15 KFH44447.1 - 4.4e-86 288.6 0.0 6.5e-86 288.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 KFH44447.1 - 0.11 11.6 0.0 1.5 7.9 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 KFH44447.1 - 0.12 11.9 0.0 0.59 9.6 0.0 1.9 1 1 1 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) TPR_11 PF13414.1 KFH44448.1 - 1.6e-56 187.8 22.3 2.1e-16 59.3 0.5 6.6 4 2 3 7 7 7 7 TPR repeat TPR_1 PF00515.23 KFH44448.1 - 6.8e-39 129.9 18.3 3.2e-06 26.4 0.1 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 KFH44448.1 - 4.6e-36 119.8 15.3 0.00015 21.3 0.0 9.8 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.1 KFH44448.1 - 9.6e-21 73.5 4.3 1.6e-11 43.9 0.3 5.7 3 3 2 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 KFH44448.1 - 1.3e-18 65.7 7.5 0.083 13.5 0.0 9.2 5 3 4 9 9 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 KFH44448.1 - 8.2e-15 55.0 17.8 5.6e-05 23.7 0.1 6.9 4 3 4 8 8 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 KFH44448.1 - 1.2e-14 53.2 8.8 0.064 13.4 0.1 8.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFH44448.1 - 1.3e-13 49.6 19.6 0.001 18.6 0.0 8.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFH44448.1 - 2.5e-13 48.7 6.7 0.00088 18.8 0.1 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFH44448.1 - 7.9e-09 35.2 0.7 0.041 13.7 0.0 4.8 5 2 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFH44448.1 - 2.1e-08 34.3 16.0 0.0032 17.7 0.0 7.1 6 2 1 8 8 7 3 Tetratricopeptide repeat Apc3 PF12895.2 KFH44448.1 - 2.7e-05 24.2 7.0 0.0009 19.3 0.5 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KFH44448.1 - 0.00011 22.4 15.0 2 9.0 0.0 7.7 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_10 PF13374.1 KFH44448.1 - 0.0012 18.7 0.5 0.095 12.6 0.0 4.1 5 0 0 5 5 4 1 Tetratricopeptide repeat DUF968 PF06147.6 KFH44448.1 - 0.0086 15.9 2.6 0.21 11.4 0.4 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF968) MxiH PF09392.5 KFH44448.1 - 0.057 13.9 0.0 1.6 9.3 0.0 2.9 2 2 0 2 2 2 0 Type III secretion needle MxiH like bZIP_1 PF00170.16 KFH44451.1 - 0.041 13.8 0.3 0.075 13.0 0.2 1.4 1 0 0 1 1 1 0 bZIP transcription factor Rhodanese PF00581.15 KFH44452.1 - 3.6e-09 36.9 0.0 5.6e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Mito_carr PF00153.22 KFH44453.1 - 3.2e-66 219.0 2.3 1.9e-22 78.7 0.0 4.2 4 0 0 4 4 4 4 Mitochondrial carrier protein MBOAT PF03062.14 KFH44454.1 - 7.5e-44 150.1 25.0 8.9e-44 149.9 12.1 2.3 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family PufQ PF05398.6 KFH44454.1 - 0.35 10.9 2.4 1 9.4 0.2 2.7 3 0 0 3 3 3 0 PufQ cytochrome subunit PrgI PF12666.2 KFH44454.1 - 0.45 10.6 7.0 1.5 8.9 1.0 3.5 3 0 0 3 3 3 0 PrgI family protein NTR2 PF15458.1 KFH44456.1 - 7.4e-70 235.0 20.6 1.1e-69 234.5 14.3 1.3 1 0 0 1 1 1 1 Nineteen complex-related protein 2 DUF4527 PF15030.1 KFH44456.1 - 0.028 13.7 0.3 0.05 12.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) Atg14 PF10186.4 KFH44456.1 - 0.34 9.8 8.5 1.7 7.4 0.7 2.5 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 2OG-FeII_Oxy PF03171.15 KFH44457.1 - 0.0034 17.6 0.0 0.013 15.8 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GTP_EFTU PF00009.22 KFH44458.1 - 2.1e-41 141.4 0.0 3.5e-41 140.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KFH44458.1 - 2.6e-27 94.7 0.0 6.9e-27 93.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 KFH44458.1 - 9.7e-13 47.8 0.0 2.3e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KFH44458.1 - 7.1e-09 35.6 2.0 1.3e-08 34.7 0.0 2.5 3 0 0 3 3 3 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KFH44458.1 - 1.5e-06 27.9 0.1 1.2e-05 25.0 0.0 2.3 2 0 0 2 2 2 1 Elongation Factor G, domain II Miro PF08477.8 KFH44458.1 - 0.091 13.2 0.0 0.26 11.7 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein MARVEL PF01284.18 KFH44459.1 - 0.00015 21.5 17.8 0.002 17.9 12.4 2.2 1 1 0 1 1 1 1 Membrane-associating domain Thioredoxin_4 PF13462.1 KFH44462.1 - 0.007 16.3 0.0 0.021 14.8 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.15 KFH44462.1 - 0.03 13.8 1.3 1 8.8 0.1 2.6 2 1 0 2 2 2 0 DSBA-like thioredoxin domain Hemerythrin PF01814.18 KFH44464.1 - 1.8e-09 37.8 0.5 2.4e-09 37.4 0.4 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Chromate_transp PF02417.10 KFH44465.1 - 6.1e-49 165.8 35.2 1e-27 96.8 10.8 2.5 3 0 0 3 3 3 2 Chromate transporter DUF2955 PF11168.3 KFH44465.1 - 0.0034 17.0 10.9 0.29 10.8 2.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF2955) NADHdh-2_N PF12155.3 KFH44465.1 - 0.075 13.2 2.2 0.16 12.1 0.6 2.2 1 1 1 2 2 2 0 NADH dehydrogenase subunit 2 N-terminal Cation_ATPase_C PF00689.16 KFH44465.1 - 0.28 10.6 5.4 0.74 9.3 0.1 3.1 3 0 0 3 3 3 0 Cation transporting ATPase, C-terminus zf-C2H2 PF00096.21 KFH44466.1 - 5.3e-05 23.3 0.8 5.3e-05 23.3 0.6 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFH44466.1 - 0.00016 21.7 6.9 0.0053 17.0 0.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFH44466.1 - 0.021 14.7 0.5 0.06 13.2 0.4 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_3 PF13878.1 KFH44466.1 - 0.19 11.3 0.2 0.19 11.3 0.1 1.8 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO DUF59 PF01883.14 KFH44467.1 - 0.00014 21.7 0.0 0.00035 20.5 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function DUF59 DUF2236 PF09995.4 KFH44468.1 - 7.1e-51 172.8 1.0 1e-50 172.3 0.7 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) SAS4 PF15460.1 KFH44469.1 - 8.4e-36 121.8 0.2 2.1e-35 120.6 0.1 1.7 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 PI3K_1B_p101 PF10486.4 KFH44469.1 - 0.13 9.7 0.9 0.17 9.3 0.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit BTV_NS2 PF04514.7 KFH44469.1 - 0.75 8.6 6.6 1.5 7.6 4.5 1.5 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Adaptin_binding PF10199.4 KFH44469.1 - 0.8 9.9 11.8 0.16 12.2 5.2 2.0 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 CDC45 PF02724.9 KFH44469.1 - 1.3 6.9 7.3 1.8 6.4 5.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Fasciclin PF02469.17 KFH44470.1 - 0.0047 16.9 0.0 0.0073 16.3 0.0 1.4 1 1 0 1 1 1 1 Fasciclin domain PAH PF02671.16 KFH44471.1 - 3e-43 145.2 1.7 7.9e-18 63.8 0.5 3.6 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 KFH44471.1 - 5.4e-39 132.0 0.2 1.9e-38 130.2 0.0 2.1 2 0 0 2 2 2 1 Sin3 family co-repressor MtrG PF04210.8 KFH44471.1 - 0.25 11.0 0.0 0.6 9.8 0.0 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G WD40 PF00400.27 KFH44472.1 - 1.4e-09 37.4 7.2 0.0012 18.6 0.4 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat LicD PF04991.8 KFH44473.1 - 4.2e-31 108.6 8.6 1.9e-29 103.2 5.9 2.1 1 1 0 1 1 1 1 LicD family Pkinase PF00069.20 KFH44474.1 - 5.7e-25 87.9 0.0 3.8e-24 85.2 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH44474.1 - 0.00032 19.8 0.3 0.036 13.1 0.0 2.8 2 1 0 2 2 2 1 Protein tyrosine kinase Zip PF02535.17 KFH44475.1 - 8.1e-48 163.0 0.2 1.1e-47 162.6 0.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Alpha-amylase PF00128.19 KFH44476.1 - 5.4e-104 347.9 0.4 1e-103 347.0 0.3 1.4 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 KFH44476.1 - 0.0072 16.4 0.0 0.026 14.6 0.0 2.1 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain hDGE_amylase PF14701.1 KFH44476.1 - 0.0073 15.2 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme DUF3459 PF11941.3 KFH44476.1 - 0.098 12.7 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) Glyco_transf_22 PF03901.12 KFH44477.1 - 3.3e-42 144.9 17.5 4.4e-42 144.5 12.1 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF962 PF06127.6 KFH44479.1 - 5.8e-28 96.6 2.0 8.2e-28 96.1 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF962) MARVEL PF01284.18 KFH44479.1 - 0.35 10.6 5.7 0.19 11.5 1.0 2.0 1 1 1 2 2 2 0 Membrane-associating domain UCH PF00443.24 KFH44480.1 - 1.2e-61 208.2 0.0 1.2e-61 208.2 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFH44480.1 - 7e-27 94.6 8.1 1.3e-22 80.6 0.0 2.9 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 KFH44480.1 - 0.24 10.6 4.4 11 5.2 3.1 2.7 1 1 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF809 PF05663.6 KFH44480.1 - 0.43 10.4 5.2 0.91 9.4 3.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF809) AAA PF00004.24 KFH44481.1 - 5.3e-16 59.0 0.0 1.8e-15 57.2 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KFH44481.1 - 3.4e-12 46.3 0.0 1.1e-11 44.6 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 KFH44481.1 - 6.2e-12 45.3 0.1 2e-11 43.7 0.0 1.9 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA_22 PF13401.1 KFH44481.1 - 3.6e-07 30.3 0.0 6.6e-06 26.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.10 KFH44481.1 - 9e-07 27.9 0.9 0.09 11.4 0.2 3.1 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 KFH44481.1 - 1.7e-05 24.5 0.0 5.1e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 KFH44481.1 - 1.9e-05 24.3 0.0 3.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFH44481.1 - 4.5e-05 23.5 0.0 0.0025 17.8 0.0 2.9 2 1 0 3 3 3 1 AAA ATPase domain DNA_pol3_delta PF06144.8 KFH44481.1 - 6.2e-05 22.5 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 KFH44481.1 - 0.00016 21.5 0.0 0.0003 20.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 KFH44481.1 - 0.00064 18.7 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.16 KFH44481.1 - 0.00083 18.5 0.0 0.041 13.0 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 KFH44481.1 - 0.00092 18.3 0.0 0.0032 16.5 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 KFH44481.1 - 0.0033 17.0 0.4 0.0074 15.8 0.3 1.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KFH44481.1 - 0.0039 16.6 0.0 0.016 14.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFH44481.1 - 0.0045 17.7 0.0 0.01 16.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFH44481.1 - 0.0098 15.6 0.1 0.042 13.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 KFH44481.1 - 0.01 15.7 0.0 0.025 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KFH44481.1 - 0.014 14.9 0.0 0.12 11.9 0.0 2.4 2 2 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KFH44481.1 - 0.016 14.6 0.1 0.34 10.2 0.0 2.5 1 1 0 2 2 2 0 AAA-like domain TIP49 PF06068.8 KFH44481.1 - 0.022 13.4 0.0 2 7.0 0.0 2.3 2 0 0 2 2 2 0 TIP49 C-terminus AAA_33 PF13671.1 KFH44481.1 - 0.028 14.3 0.0 0.052 13.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KFH44481.1 - 0.033 13.6 0.0 0.11 11.9 0.0 1.9 2 1 0 2 2 2 0 FtsK/SpoIIIE family AAA_18 PF13238.1 KFH44481.1 - 0.041 14.1 0.0 0.11 12.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 KFH44481.1 - 0.047 12.5 0.0 0.081 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_3 PF07726.6 KFH44481.1 - 0.06 12.9 0.0 0.42 10.2 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SNF2_N PF00176.18 KFH44481.1 - 0.077 11.7 0.0 1.6 7.4 0.0 2.1 1 1 0 2 2 2 0 SNF2 family N-terminal domain RNA_helicase PF00910.17 KFH44481.1 - 0.096 12.8 0.0 0.2 11.8 0.0 1.7 1 1 0 1 1 1 0 RNA helicase DEAD PF00270.24 KFH44481.1 - 0.12 11.8 0.2 1.9 7.9 0.0 2.4 1 1 0 2 2 2 0 DEAD/DEAH box helicase ResIII PF04851.10 KFH44481.1 - 0.13 12.0 0.0 0.59 9.9 0.0 1.9 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_23 PF13476.1 KFH44481.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain Sec63 PF02889.11 KFH44482.1 - 3.5e-189 627.6 0.3 2.7e-106 355.3 0.0 3.0 2 1 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KFH44482.1 - 2e-55 186.8 0.7 5.7e-32 110.5 0.0 4.4 5 0 0 5 5 5 2 DEAD/DEAH box helicase ResIII PF04851.10 KFH44482.1 - 2.2e-17 63.4 0.5 9.5e-09 35.3 0.0 3.2 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KFH44482.1 - 2.1e-10 40.3 0.0 1.8e-09 37.3 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KFH44482.1 - 2.1e-07 31.1 0.0 0.0059 16.7 0.0 3.2 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 KFH44482.1 - 0.00014 21.1 0.0 0.039 13.1 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_19 PF13245.1 KFH44482.1 - 0.003 17.2 0.0 0.59 9.9 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain T2SE PF00437.15 KFH44482.1 - 0.0042 16.0 0.0 1.3 7.8 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_10 PF12846.2 KFH44482.1 - 0.008 15.6 0.2 2 7.7 0.0 3.9 4 1 0 4 4 4 1 AAA-like domain AAA_23 PF13476.1 KFH44482.1 - 9.6 6.4 7.7 15 5.8 0.1 3.8 4 0 0 4 4 4 0 AAA domain zf-HIT PF04438.11 KFH44483.1 - 1.1e-09 37.7 4.4 1.6e-09 37.2 3.0 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-B_box PF00643.19 KFH44483.1 - 8.4 6.3 8.0 92 3.0 0.1 2.1 1 1 1 2 2 2 0 B-box zinc finger WD40 PF00400.27 KFH44484.1 - 8e-08 31.8 0.1 6.1e-07 29.0 0.0 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF2415 PF10313.4 KFH44484.1 - 9.4e-05 22.0 0.0 0.0004 20.0 0.0 2.1 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) Fungal_trans_2 PF11951.3 KFH44485.1 - 1.6e-10 40.1 0.7 3.4e-08 32.5 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain MFS_1 PF07690.11 KFH44486.1 - 5.6e-32 110.8 22.8 5.6e-32 110.8 15.8 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sec66 PF09802.4 KFH44487.1 - 3.5e-78 261.3 0.2 4.1e-78 261.1 0.1 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF4456 PF14644.1 KFH44487.1 - 0.038 13.2 1.2 0.067 12.4 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) Duffy_binding PF05424.6 KFH44487.1 - 1.1 9.0 6.5 4.1 7.1 4.5 1.8 1 1 0 1 1 1 0 Duffy binding domain RNB PF00773.14 KFH44488.1 - 4.2e-51 174.1 0.0 5.9e-51 173.6 0.0 1.2 1 0 0 1 1 1 1 RNB domain PWWP PF00855.12 KFH44489.1 - 8.1e-13 48.3 0.3 6.2e-12 45.5 0.0 2.7 2 0 0 2 2 2 1 PWWP domain ORC3_N PF07034.6 KFH44490.1 - 9.5e-38 129.9 0.2 2.7e-37 128.4 0.1 1.7 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus Met_10 PF02475.11 KFH44491.1 - 7e-71 237.9 0.0 9e-71 237.5 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 KFH44491.1 - 0.021 15.3 0.0 0.058 13.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KFH44491.1 - 0.044 13.1 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 KFH44491.1 - 0.091 12.7 0.0 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Complex1_LYR PF05347.10 KFH44492.1 - 3e-13 49.3 0.4 2.4e-05 24.0 0.0 2.0 2 0 0 2 2 2 2 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KFH44492.1 - 1.1e-11 44.7 0.2 1.5e-11 44.3 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Cu_amine_oxidN2 PF02727.11 KFH44493.1 - 0.0048 16.9 0.0 0.0058 16.6 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DUF836 PF05768.9 KFH44494.1 - 1.1e-13 51.2 0.0 1.3e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.1 KFH44494.1 - 0.0092 16.1 0.0 0.014 15.5 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin-like domain Glutaredoxin PF00462.19 KFH44494.1 - 0.011 15.7 0.0 0.025 14.5 0.0 1.7 2 0 0 2 2 2 0 Glutaredoxin Dus PF01207.12 KFH44495.1 - 2.4e-31 108.7 0.0 2.2e-26 92.4 0.0 2.4 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) DUF3602 PF12223.3 KFH44496.1 - 1.8e-13 50.6 13.8 2.5e-12 46.9 4.8 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) FAA_hydrolase PF01557.13 KFH44497.1 - 5e-63 212.4 0.0 7.8e-63 211.8 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family BAH PF01426.13 KFH44498.1 - 0.0012 18.5 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 KFH44498.1 - 0.021 14.5 3.2 0.021 14.5 2.2 1.9 2 0 0 2 2 2 0 PHD-finger Thioredoxin PF00085.15 KFH44499.1 - 2.9e-64 213.2 4.9 5.8e-31 106.2 0.0 3.9 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 KFH44499.1 - 4.5e-53 179.8 0.3 1.3e-37 129.3 0.1 3.9 2 2 2 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KFH44499.1 - 1.6e-12 47.3 0.1 0.00041 20.4 0.0 4.5 4 1 1 5 5 5 2 Thioredoxin-like Thioredoxin_7 PF13899.1 KFH44499.1 - 6.8e-11 42.0 0.1 0.0002 21.3 0.0 3.5 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.1 KFH44499.1 - 6.6e-10 39.1 2.2 0.00068 19.8 0.1 3.8 3 2 1 4 4 4 2 Thioredoxin-like domain Calsequestrin PF01216.12 KFH44499.1 - 2.8e-09 36.2 0.5 2.8e-09 36.2 0.3 2.1 2 1 0 2 2 2 1 Calsequestrin AhpC-TSA PF00578.16 KFH44499.1 - 4.4e-07 29.6 0.8 0.036 13.7 0.0 3.2 3 1 1 4 4 4 2 AhpC/TSA family Redoxin PF08534.5 KFH44499.1 - 1.4e-05 24.6 2.0 0.019 14.5 0.0 3.4 3 1 1 4 4 4 2 Redoxin Thioredoxin_4 PF13462.1 KFH44499.1 - 0.00031 20.8 2.4 0.28 11.1 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_3 PF13192.1 KFH44499.1 - 0.0078 15.9 0.3 0.044 13.5 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin domain DSBA PF01323.15 KFH44499.1 - 0.074 12.5 0.2 20 4.6 0.0 3.0 2 1 1 3 3 3 0 DSBA-like thioredoxin domain ICL PF00463.16 KFH44500.1 - 2e-121 405.8 1.2 2.4e-121 405.5 0.8 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KFH44500.1 - 3.1e-07 29.8 0.0 6.2e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase TFIIA PF03153.8 KFH44501.1 - 0.57 10.0 4.9 0.6 9.9 3.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 KFH44501.1 - 1.6 6.8 8.4 2 6.5 5.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PRCC PF10253.4 KFH44501.1 - 2 9.1 6.3 3.6 8.2 4.4 1.5 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Dicty_REP PF05086.7 KFH44501.1 - 2.5 5.7 3.5 2.9 5.5 2.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Prenyltransf PF01255.14 KFH44502.1 - 2.8e-13 49.5 0.0 1.6e-12 47.0 0.0 1.9 2 0 0 2 2 2 1 Putative undecaprenyl diphosphate synthase RTC4 PF14474.1 KFH44503.1 - 2.2e-29 101.9 0.0 3.9e-29 101.0 0.0 1.5 1 0 0 1 1 1 1 RTC4-like domain DUF1648 PF07853.6 KFH44503.1 - 0.024 14.1 0.1 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1648) 2OG-FeII_Oxy_2 PF13532.1 KFH44504.1 - 9.7e-30 103.8 0.0 1.3e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KFH44504.1 - 5.7e-06 26.5 0.0 1.4e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily APH PF01636.18 KFH44505.1 - 1e-46 159.5 0.0 2.2e-46 158.5 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KFH44505.1 - 1.4e-07 30.9 0.1 3.3e-07 29.7 0.1 1.7 1 1 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 KFH44505.1 - 6.8e-06 25.8 0.0 1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KFH44505.1 - 0.0058 16.0 0.0 0.37 10.1 0.0 2.2 2 0 0 2 2 2 1 RIO1 family DUF1679 PF07914.6 KFH44505.1 - 0.0078 14.8 0.0 0.033 12.8 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) PP2C PF00481.16 KFH44506.1 - 8e-56 189.2 0.0 1.4e-55 188.4 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 KFH44506.1 - 1.6e-54 180.7 58.7 5.3e-07 29.1 0.0 12.7 8 4 5 13 13 13 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFH44506.1 - 1.4e-38 130.3 55.0 1.7e-08 34.0 1.2 9.8 3 2 10 13 13 13 11 Leucine rich repeat Guanylate_cyc PF00211.15 KFH44506.1 - 2.1e-30 105.4 0.0 4.9e-30 104.2 0.0 1.5 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 KFH44506.1 - 8.2e-25 83.0 58.6 0.23 11.6 0.0 20.2 19 2 1 20 20 20 9 Leucine Rich Repeat LRR_7 PF13504.1 KFH44506.1 - 5.8e-15 52.8 49.9 0.44 10.9 0.1 17.3 18 0 0 18 18 17 4 Leucine rich repeat Ad_cyc_g-alpha PF08509.6 KFH44506.1 - 1.2e-14 53.3 1.0 1.2e-14 53.3 0.7 2.3 2 0 0 2 2 2 1 Adenylate cyclase G-alpha binding domain LRR_6 PF13516.1 KFH44506.1 - 8.7e-08 31.4 48.8 0.6 10.3 0.1 16.1 17 2 0 17 17 17 2 Leucine Rich repeat RA PF00788.18 KFH44506.1 - 2.1e-07 31.3 0.0 9.2e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain DUF3708 PF12501.3 KFH44506.1 - 0.25 11.1 0.2 6.8 6.5 0.0 2.5 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter DUF2065 PF09838.4 KFH44506.1 - 0.45 10.2 0.1 1.1 9.0 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2065) Yos1 PF08571.5 KFH44507.1 - 1.1e-27 95.8 0.2 1.3e-27 95.7 0.2 1.0 1 0 0 1 1 1 1 Yos1-like PsbL PF02419.12 KFH44507.1 - 0.057 12.8 0.2 0.14 11.6 0.2 1.6 1 0 0 1 1 1 0 PsbL protein Hydantoinase_B PF02538.9 KFH44508.1 - 2.9e-184 613.1 0.0 3.8e-184 612.8 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KFH44508.1 - 1e-87 293.9 1.6 1.6e-87 293.3 0.1 2.0 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KFH44508.1 - 6.4e-54 182.1 0.0 5e-52 175.9 0.0 2.3 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Proteasome_A_N PF10584.4 KFH44508.1 - 0.014 14.6 0.0 0.031 13.5 0.0 1.5 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature SHS2_Rpb7-N PF03876.12 KFH44509.1 - 9.3e-16 57.7 0.0 1.5e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 KFH44509.1 - 5.7e-15 55.1 0.0 8.5e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 KFH44509.1 - 0.029 14.5 0.0 0.088 13.0 0.0 1.8 1 1 0 1 1 1 0 RNA polymerase III subunit Rpc25 DUF2526 PF10735.4 KFH44510.1 - 0.27 11.2 1.6 0.65 10.0 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2526) Mito_carr PF00153.22 KFH44511.1 - 2.8e-51 171.1 8.4 8.8e-19 67.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UQ_con PF00179.21 KFH44512.1 - 1e-38 131.9 0.0 4.6e-25 87.6 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFH44512.1 - 3.6e-06 26.7 0.0 0.055 13.2 0.0 2.4 2 0 0 2 2 2 2 Prokaryotic E2 family B RWD PF05773.17 KFH44512.1 - 0.0019 18.0 0.0 0.96 9.3 0.0 2.5 2 1 0 2 2 2 2 RWD domain DUF4333 PF14230.1 KFH44512.1 - 0.12 12.3 0.1 5.6 6.9 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4333) tRNA-synt_2b PF00587.20 KFH44513.1 - 1.7e-42 144.9 0.1 3.2e-42 144.0 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KFH44513.1 - 2.3e-17 62.7 0.1 4.9e-17 61.6 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 KFH44513.1 - 2.4e-11 43.3 0.0 8.2e-11 41.6 0.0 2.0 1 1 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 KFH44513.1 - 3.5e-10 39.5 0.0 8.4e-10 38.3 0.0 1.7 1 0 0 1 1 1 1 TGS domain NPL4 PF05021.10 KFH44516.1 - 3.7e-128 426.9 0.0 4.7e-128 426.6 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 KFH44516.1 - 9.1e-69 229.7 0.0 1.4e-68 229.1 0.0 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 KFH44516.1 - 0.0013 18.9 0.0 0.0029 17.8 0.0 1.6 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 Trypan_PARP PF05887.6 KFH44517.1 - 0.24 11.2 42.2 1.6 8.5 19.2 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF2457 PF10446.4 KFH44518.1 - 0.0021 16.8 3.8 0.0028 16.4 2.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Ribosomal_S4 PF00163.14 KFH44518.1 - 1.9 8.9 5.0 1 9.8 1.7 1.9 2 0 0 2 2 2 0 Ribosomal protein S4/S9 N-terminal domain DUF1752 PF08550.5 KFH44519.1 - 5.5e-10 38.6 3.2 1.2e-09 37.5 2.2 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Exonuc_VII_S PF02609.11 KFH44520.1 - 0.02 14.6 1.1 0.077 12.7 0.5 2.2 2 0 0 2 2 2 0 Exonuclease VII small subunit ThiS PF02597.15 KFH44521.1 - 3.3e-09 37.0 0.0 1.2e-08 35.2 0.0 1.7 1 1 0 1 1 1 1 ThiS family CAF-1_p150 PF11600.3 KFH44522.1 - 0.0026 17.1 15.8 0.0026 17.1 10.9 3.0 3 0 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1777 PF08648.7 KFH44522.1 - 0.0085 15.8 40.1 0.0085 15.8 27.8 3.6 3 1 0 3 3 3 1 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 KFH44522.1 - 0.081 11.3 48.8 0.48 8.8 12.8 2.2 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 CPSase_L_D2 PF02786.12 KFH44523.1 - 5e-112 372.3 0.1 2.6e-85 284.9 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 KFH44523.1 - 1.9e-41 140.6 0.0 4.9e-41 139.3 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 KFH44523.1 - 1.5e-39 135.6 0.8 2.2e-22 79.6 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp domain CPSase_L_chain PF00289.17 KFH44523.1 - 1.1e-34 118.7 0.0 5.8e-16 58.5 0.0 2.7 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 KFH44523.1 - 3.9e-26 91.5 0.0 3.7e-11 42.3 0.0 3.7 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KFH44523.1 - 7.9e-23 80.6 0.2 4.2e-11 42.4 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KFH44523.1 - 1.2e-18 67.2 1.3 1.4e-09 37.6 0.2 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 KFH44523.1 - 6.3e-09 35.5 0.0 9.7e-06 25.1 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 KFH44523.1 - 7.2e-07 29.2 1.2 0.042 13.7 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain GARS_A PF01071.14 KFH44523.1 - 8.5e-07 28.7 0.6 0.043 13.3 0.0 2.7 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.1 KFH44523.1 - 4.3e-05 22.8 0.1 0.13 11.4 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain Sec10 PF07393.6 KFH44524.1 - 5e-226 752.2 4.3 6e-226 751.9 3.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 HpcH_HpaI PF03328.9 KFH44525.1 - 7.9e-37 126.2 0.1 1e-36 125.9 0.1 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP_mutase PF13714.1 KFH44525.1 - 0.00024 20.3 0.4 0.1 11.8 0.0 3.1 1 1 2 4 4 4 2 Phosphoenolpyruvate phosphomutase IBR PF01485.16 KFH44526.1 - 1.1e-08 34.7 34.2 1.1e-06 28.3 9.9 3.1 3 0 0 3 3 3 2 IBR domain Aromatic_hydrox PF11723.3 KFH44526.1 - 0.062 12.5 1.3 0.12 11.6 0.9 1.4 1 0 0 1 1 1 0 Homotrimeric ring hydroxylase CHORD PF04968.7 KFH44527.1 - 2.1e-50 168.8 17.1 2.9e-25 88.2 2.9 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.11 KFH44527.1 - 3.9e-15 56.1 0.0 5.7e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 CS domain ATG22 PF11700.3 KFH44529.1 - 2.4e-194 646.2 14.7 2.8e-194 646.0 10.2 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like DUF1469 PF07332.6 KFH44529.1 - 3.1 7.5 12.0 3.7 7.3 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Fungal_trans PF04082.13 KFH44530.1 - 1.2e-17 63.6 3.9 1.2e-17 63.6 2.7 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH44530.1 - 6.2e-08 32.4 11.4 1.2e-07 31.5 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F_actin_cap_B PF01115.12 KFH44531.1 - 1.1e-106 355.4 0.0 1.2e-106 355.2 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit P3A PF08727.6 KFH44531.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Poliovirus 3A protein like CBS PF00571.23 KFH44532.1 - 0.00082 19.1 0.0 0.15 11.8 0.0 2.6 2 1 1 3 3 3 2 CBS domain Aminotran_1_2 PF00155.16 KFH44533.1 - 3.9e-15 55.6 0.0 7.1e-15 54.8 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KFH44533.1 - 0.0067 15.0 0.0 0.012 14.2 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Acyl-CoA_dh_1 PF00441.19 KFH44534.1 - 1.8e-34 119.0 0.7 3.2e-34 118.2 0.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFH44534.1 - 1.1e-11 44.0 0.3 2.1e-11 43.1 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KFH44534.1 - 2.4e-11 44.0 0.3 5e-11 42.9 0.2 1.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFH44534.1 - 2.5e-07 31.2 0.0 5.3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.3 KFH44534.1 - 0.047 13.0 0.0 0.12 11.6 0.0 1.6 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Dynamitin PF04912.9 KFH44535.1 - 1.4e-37 129.4 2.4 5.6e-36 124.1 1.6 2.2 1 1 0 1 1 1 1 Dynamitin FH2 PF02181.18 KFH44535.1 - 0.004 16.0 3.7 1.2 7.9 0.0 2.9 3 0 0 3 3 3 2 Formin Homology 2 Domain Spore_III_AB PF09548.5 KFH44535.1 - 0.0099 15.6 2.0 0.11 12.2 0.0 2.8 3 0 0 3 3 3 1 Stage III sporulation protein AB (spore_III_AB) Phage_GP20 PF06810.6 KFH44535.1 - 0.039 13.4 0.3 0.039 13.4 0.2 3.1 3 0 0 3 3 3 0 Phage minor structural protein GP20 Snapin_Pallidin PF14712.1 KFH44535.1 - 0.058 13.7 8.5 0.91 9.8 0.2 4.3 3 2 1 4 4 4 0 Snapin/Pallidin DivIC PF04977.10 KFH44535.1 - 0.084 12.3 15.0 1.9 8.0 0.4 3.5 3 0 0 3 3 3 0 Septum formation initiator FAM222A PF15258.1 KFH44535.1 - 0.086 12.0 0.9 1.9 7.5 0.0 2.4 2 1 0 3 3 3 0 Protein family of FAM222A Laminin_II PF06009.7 KFH44535.1 - 0.1 12.3 9.6 0.14 11.8 0.3 3.7 3 1 1 4 4 4 0 Laminin Domain II Baculo_PEP_C PF04513.7 KFH44535.1 - 0.12 12.2 0.2 5.6 6.7 0.1 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATP-synt_E PF05680.7 KFH44535.1 - 0.17 11.8 0.1 0.17 11.8 0.1 3.0 3 1 0 3 3 3 0 ATP synthase E chain DUF812 PF05667.6 KFH44535.1 - 0.17 10.3 7.8 1 7.8 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF812) DUF3287 PF11690.3 KFH44535.1 - 0.2 11.7 1.3 15 5.6 0.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3287) AAA_13 PF13166.1 KFH44535.1 - 0.31 9.4 1.4 1.4 7.2 0.3 2.1 2 1 0 2 2 2 0 AAA domain GrpE PF01025.14 KFH44535.1 - 0.34 10.4 11.4 2.1 7.8 1.1 3.5 2 1 1 3 3 3 0 GrpE Cluap1 PF10234.4 KFH44535.1 - 0.43 9.7 8.5 1 8.4 0.1 3.0 3 0 0 3 3 3 0 Clusterin-associated protein-1 HWE_HK PF07536.9 KFH44535.1 - 0.44 11.0 3.5 0.48 10.9 0.5 2.5 2 0 0 2 2 2 0 HWE histidine kinase Flagellin_N PF00669.15 KFH44535.1 - 0.55 10.0 5.2 0.3 10.8 0.3 2.7 3 0 0 3 3 3 0 Bacterial flagellin N-terminal helical region CENP-Q PF13094.1 KFH44535.1 - 0.72 9.8 12.9 3.6 7.5 0.6 3.3 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Sipho_Gp157 PF05565.6 KFH44535.1 - 1.1 8.7 7.1 7 6.2 0.0 2.7 3 0 0 3 3 3 0 Siphovirus Gp157 COG2 PF06148.6 KFH44535.1 - 1.3 8.8 6.0 15 5.4 0.2 3.2 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc24 PF08286.6 KFH44535.1 - 1.5 8.5 9.0 4.5 7.0 0.2 3.2 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 BRE1 PF08647.6 KFH44535.1 - 1.6 8.7 9.4 14 5.7 0.2 3.4 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase ADIP PF11559.3 KFH44535.1 - 2.7 7.8 13.0 6 6.7 0.3 3.2 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding BLOC1_2 PF10046.4 KFH44535.1 - 2.9 8.0 8.0 15 5.7 0.2 3.9 3 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prefoldin_2 PF01920.15 KFH44535.1 - 3.1 7.6 10.2 10 5.9 0.1 4.0 3 1 1 4 4 4 0 Prefoldin subunit Chitin_synth_2 PF03142.10 KFH44536.1 - 9.2e-233 773.4 0.0 1.3e-232 772.9 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 KFH44536.1 - 4e-56 190.4 0.0 1.5e-55 188.5 0.0 1.9 1 1 0 1 1 1 1 Myosin head (motor domain) Glyco_trans_2_3 PF13632.1 KFH44536.1 - 4.4e-18 65.6 1.7 4.4e-18 65.6 1.2 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KFH44536.1 - 6.6e-17 62.0 0.0 5e-14 52.6 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 KFH44536.1 - 4.4e-14 52.0 1.6 1.8e-10 40.4 0.1 2.6 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 KFH44536.1 - 1.5e-12 47.0 3.2 1.2e-11 44.2 2.0 2.4 2 0 0 2 2 2 1 DEK C terminal domain Glyco_transf_21 PF13506.1 KFH44536.1 - 1.1e-06 28.0 0.0 3.4e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KFH44536.1 - 0.00075 19.2 0.0 0.063 12.9 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 HSP70 PF00012.15 KFH44537.1 - 2.8e-168 560.5 6.2 2.8e-168 560.5 4.3 1.8 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFH44537.1 - 4e-13 48.6 0.0 3.1e-12 45.7 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 KFH44537.1 - 4e-06 26.6 1.1 0.11 12.2 0.0 3.6 2 1 0 2 2 2 2 Cell division protein FtsA Fungal_trans PF04082.13 KFH44538.1 - 2.6e-25 88.7 0.0 2.2e-24 85.7 0.0 2.4 2 2 1 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH44538.1 - 1.8e-08 34.1 9.0 3.2e-08 33.3 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4306 PF14154.1 KFH44538.1 - 0.0083 16.0 0.3 0.015 15.2 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4306) AflR PF08493.5 KFH44538.1 - 0.024 13.7 0.1 0.024 13.7 0.0 1.9 2 0 0 2 2 2 0 Aflatoxin regulatory protein Fungal_trans_2 PF11951.3 KFH44538.1 - 0.054 12.0 0.1 0.29 9.6 0.0 1.9 2 0 0 2 2 2 0 Fungal specific transcription factor domain His_Phos_2 PF00328.17 KFH44539.1 - 1.4e-50 172.6 0.0 1.5e-50 172.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) MIF4G PF02854.14 KFH44540.1 - 2.7e-57 193.5 0.0 1e-25 90.3 0.0 4.4 5 0 0 5 5 5 3 MIF4G domain Upf2 PF04050.9 KFH44540.1 - 2.4e-54 183.6 18.6 2.4e-54 183.6 12.9 2.0 2 0 0 2 2 2 1 Up-frameshift suppressor 2 SDP_N PF12278.3 KFH44540.1 - 0.061 12.9 7.1 1.4 8.5 0.3 2.9 2 0 0 2 2 2 0 Sex determination protein N terminal TCTP PF00838.12 KFH44540.1 - 1.8 8.5 8.1 0.69 9.8 0.1 3.1 3 0 0 3 3 3 0 Translationally controlled tumour protein Ran_BP1 PF00638.13 KFH44541.1 - 3.5e-13 49.6 0.1 1.3e-05 25.2 0.0 2.3 2 0 0 2 2 2 2 RanBP1 domain MARVEL PF01284.18 KFH44542.1 - 7.3e-06 25.8 20.3 1.1e-05 25.2 14.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain Shisa PF13908.1 KFH44542.1 - 0.0049 17.0 2.7 0.0087 16.2 1.9 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Npa1 PF11707.3 KFH44543.1 - 1.9e-76 257.1 0.0 3.1e-76 256.4 0.0 1.4 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal Arm PF00514.18 KFH44543.1 - 0.081 12.7 1.0 2.3 8.1 0.0 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Acyl_transf_1 PF00698.16 KFH44544.1 - 6e-81 272.2 0.0 3.9e-79 266.2 0.0 3.0 3 0 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.14 KFH44544.1 - 1.2e-37 128.0 0.0 2.8e-37 126.8 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 KFH44544.1 - 1.3e-29 101.7 1.1 3.7e-29 100.2 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 KFH44544.1 - 4.1e-23 81.6 0.1 2.3e-22 79.2 0.0 2.5 3 0 0 3 3 3 1 N-terminal half of MaoC dehydratase NMO PF03060.10 KFH44544.1 - 0.00073 18.7 0.1 0.018 14.1 0.1 2.4 2 0 0 2 2 2 1 Nitronate monooxygenase EcoEI_R_C PF08463.5 KFH44544.1 - 0.28 11.0 0.1 0.59 9.9 0.0 1.5 1 0 0 1 1 1 0 EcoEI R protein C-terminal PLA2_B PF01735.13 KFH44545.1 - 3.4e-29 101.3 0.0 5.4e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain RE_NgoPII PF09521.5 KFH44545.1 - 0.01 14.6 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 NgoPII restriction endonuclease LSM PF01423.17 KFH44546.1 - 3.6e-16 58.4 0.0 5.5e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KFH44546.1 - 0.085 12.7 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain GTP_EFTU PF00009.22 KFH44547.1 - 2.2e-32 112.0 0.0 1.1e-31 109.7 0.0 2.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KFH44547.1 - 2.2e-18 66.1 0.0 5.9e-18 64.7 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KFH44547.1 - 2.4e-11 43.5 5.6 7.6e-08 32.3 0.0 3.2 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KFH44547.1 - 3.9e-06 26.7 0.1 1.9e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase TrkA_C PF02080.16 KFH44547.1 - 0.004 16.7 0.3 1.5 8.4 0.0 3.3 3 0 0 3 3 3 1 TrkA-C domain GTP_EFTU_D4 PF14578.1 KFH44547.1 - 0.0043 16.6 0.1 0.011 15.3 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 AAA_16 PF13191.1 KFH44547.1 - 0.08 12.9 0.0 0.08 12.9 0.0 3.4 1 1 1 2 2 2 0 AAA ATPase domain Miro PF08477.8 KFH44547.1 - 0.15 12.5 0.0 0.15 12.5 0.0 3.2 4 0 0 4 4 4 0 Miro-like protein Inositol_P PF00459.20 KFH44548.1 - 4.5e-60 203.2 0.0 5.4e-60 202.9 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family WD40 PF00400.27 KFH44549.1 - 7.2e-15 54.2 16.4 6.3e-05 22.6 0.1 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat MMS1_N PF10433.4 KFH44550.1 - 1.3e-76 257.8 0.0 3.1e-76 256.5 0.0 1.6 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 KFH44550.1 - 0.0014 17.7 0.0 0.0038 16.3 0.0 1.6 1 1 0 1 1 1 1 CPSF A subunit region Vps52 PF04129.7 KFH44551.1 - 4.2e-122 408.2 0.1 5.3e-122 407.9 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 KFH44551.1 - 9.3e-07 27.3 0.9 1.6e-06 26.6 0.6 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec3 Exo70 PF03081.10 KFH44551.1 - 0.021 13.6 0.1 0.18 10.5 0.0 2.4 3 0 0 3 3 3 0 Exo70 exocyst complex subunit Mer2 PF09074.5 KFH44551.1 - 0.044 13.7 0.7 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 Mer2 DUF1664 PF07889.7 KFH44551.1 - 0.059 13.1 0.1 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ETC_C1_NDUFA5 PF04716.9 KFH44552.1 - 4.2e-21 74.2 0.7 2.6e-20 71.7 0.0 2.3 2 0 0 2 2 2 1 ETC complex I subunit conserved region zf-RING_2 PF13639.1 KFH44553.1 - 2.9e-14 52.6 16.2 6.1e-14 51.5 4.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFH44553.1 - 1.3e-12 47.1 9.1 2.7e-10 39.7 2.0 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFH44553.1 - 2.8e-08 33.6 15.4 1.3e-07 31.4 4.5 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFH44553.1 - 6.2e-08 32.1 14.3 5e-07 29.2 3.9 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFH44553.1 - 9.4e-07 28.4 10.4 1.1e-06 28.2 2.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 KFH44553.1 - 1.3e-06 28.3 4.4 1.3e-06 28.3 3.1 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger Prok-RING_4 PF14447.1 KFH44553.1 - 0.00073 19.0 3.9 0.0019 17.6 2.7 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 KFH44553.1 - 0.0049 16.6 2.3 0.0049 16.6 1.6 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_3 PF14369.1 KFH44553.1 - 0.008 16.1 6.2 0.015 15.2 1.9 2.5 2 0 0 2 2 2 1 zinc-finger HypA PF01155.14 KFH44553.1 - 0.0088 15.7 0.1 0.0088 15.7 0.0 1.6 2 0 0 2 2 1 1 Hydrogenase expression/synthesis hypA family DUF1272 PF06906.6 KFH44553.1 - 0.016 15.0 8.4 0.023 14.5 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) ATG11 PF10377.4 KFH44553.1 - 0.039 13.8 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 Autophagy-related protein 11 PHD PF00628.24 KFH44553.1 - 0.065 12.9 12.4 0.047 13.3 3.5 2.6 2 0 0 2 2 2 0 PHD-finger PhnA_Zn_Ribbon PF08274.7 KFH44553.1 - 0.098 12.4 4.6 0.69 9.7 0.2 2.5 1 1 1 2 2 2 0 PhnA Zinc-Ribbon Rad50_zn_hook PF04423.9 KFH44553.1 - 0.18 11.3 1.0 0.93 9.0 0.1 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif RINGv PF12906.2 KFH44553.1 - 0.2 11.7 15.0 0.048 13.7 5.1 2.4 2 0 0 2 2 2 0 RING-variant domain zf-FPG_IleRS PF06827.9 KFH44553.1 - 0.26 10.9 3.5 6.2 6.5 0.2 3.1 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS zf-RING_4 PF14570.1 KFH44553.1 - 0.41 10.2 13.4 0.41 10.2 2.8 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.1 KFH44553.1 - 0.47 10.2 11.5 6.3 6.6 0.4 3.0 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zinc-ribbons_6 PF07191.7 KFH44553.1 - 0.57 10.0 7.4 3.4 7.5 0.2 3.0 3 0 0 3 3 3 0 zinc-ribbons Baculo_RING PF05883.6 KFH44553.1 - 0.66 9.8 6.2 0.17 11.7 1.3 2.0 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain TF_Zn_Ribbon PF08271.7 KFH44553.1 - 0.86 8.9 4.1 0.79 9.0 0.3 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding zf-RING_6 PF14835.1 KFH44553.1 - 2.3 8.0 6.2 0.47 10.2 0.7 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DZR PF12773.2 KFH44553.1 - 2.8 7.8 7.1 2.2 8.1 0.2 2.5 2 1 0 2 2 2 0 Double zinc ribbon RRN7 PF11781.3 KFH44554.1 - 5.8e-05 22.4 2.3 0.00011 21.6 1.6 1.4 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 Rhodanese PF00581.15 KFH44555.1 - 5.1e-15 55.8 0.0 8.1e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Fungal_trans PF04082.13 KFH44556.1 - 3.6e-41 140.7 0.0 5.9e-41 140.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH44556.1 - 3.6e-08 33.1 6.9 8e-08 32.0 4.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RabGAP-TBC PF00566.13 KFH44557.1 - 7.2e-18 64.8 0.0 1.1e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Inhibitor_I9 PF05922.11 KFH44558.1 - 5.6e-13 49.2 0.4 6.3e-13 49.1 0.3 1.0 1 0 0 1 1 1 1 Peptidase inhibitor I9 DEAD PF00270.24 KFH44559.1 - 3.8e-25 88.3 0.0 6.3e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.5 KFH44559.1 - 2.4e-14 53.6 0.2 6.8e-14 52.2 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 KFH44559.1 - 5.4e-09 35.7 0.0 1.8e-08 34.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CDT1 PF08839.6 KFH44559.1 - 0.00061 19.7 0.0 0.0016 18.3 0.0 1.7 2 0 0 2 2 2 1 DNA replication factor CDT1 like AAA PF00004.24 KFH44560.1 - 2.2e-10 40.8 0.0 4.8e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFH44560.1 - 1.4e-06 28.4 0.0 3.8e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFH44560.1 - 3e-05 23.7 0.0 5.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KFH44560.1 - 6.6e-05 22.0 0.0 0.00013 21.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KFH44560.1 - 0.00011 21.9 0.1 0.00044 19.9 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain Rad17 PF03215.10 KFH44560.1 - 0.00015 20.6 0.0 0.00023 20.0 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_33 PF13671.1 KFH44560.1 - 0.00024 20.9 0.5 0.00083 19.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KFH44560.1 - 0.00062 20.5 0.0 0.0028 18.4 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 KFH44560.1 - 0.00089 19.1 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFH44560.1 - 0.0018 18.2 1.5 0.024 14.6 0.0 3.1 2 2 1 3 3 3 1 AAA ATPase domain DUF258 PF03193.11 KFH44560.1 - 0.014 14.5 0.1 0.036 13.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 GLTSCR1 PF15249.1 KFH44560.1 - 0.023 14.8 0.0 0.16 12.0 0.0 2.4 2 0 0 2 2 2 0 Glioma tumor suppressor candidate region NTPase_1 PF03266.10 KFH44560.1 - 0.025 14.2 0.0 0.067 12.8 0.0 1.8 1 0 0 1 1 1 0 NTPase AAA_30 PF13604.1 KFH44560.1 - 0.025 14.1 0.0 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KFH44560.1 - 0.026 14.8 0.0 0.06 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KFH44560.1 - 0.027 13.5 0.0 0.061 12.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.17 KFH44560.1 - 0.081 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain IstB_IS21 PF01695.12 KFH44560.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 KFH44560.1 - 0.12 12.0 0.0 0.67 9.6 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase BRO1 PF03097.13 KFH44561.1 - 5.8e-133 443.2 3.3 5.8e-133 443.2 2.3 2.3 2 1 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 KFH44561.1 - 1e-91 307.0 18.8 2.3e-91 305.8 13.1 1.6 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV COG2 PF06148.6 KFH44561.1 - 0.029 14.2 0.6 0.029 14.2 0.4 3.1 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4407 PF14362.1 KFH44561.1 - 2.3 7.1 24.8 0.014 14.4 5.8 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) DUF3012 PF11216.3 KFH44561.1 - 7.4 6.3 6.5 1.1 8.9 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3012) GLTP PF08718.6 KFH44562.1 - 9.1e-46 155.5 0.0 1.4e-45 154.9 0.0 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Virul_fac_BrkB PF03631.10 KFH44562.1 - 0.026 13.8 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Virulence factor BrkB Chitin_synth_2 PF03142.10 KFH44563.1 - 6.7e-254 843.1 0.6 9.1e-254 842.7 0.4 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 KFH44563.1 - 4.3e-165 550.5 0.0 5.5e-165 550.2 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.6 KFH44563.1 - 2.4e-17 62.4 0.2 2.9e-16 58.9 0.1 2.4 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.23 KFH44563.1 - 3.8e-14 52.2 0.1 5.8e-09 35.6 0.0 2.8 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 KFH44563.1 - 4.4e-14 52.6 7.4 4.4e-14 52.6 5.1 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KFH44563.1 - 8.5e-14 51.9 0.3 7.6e-11 42.2 0.1 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KFH44563.1 - 1e-05 25.2 0.0 0.00072 19.2 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF258 PF03193.11 KFH44563.1 - 0.002 17.3 0.0 0.0071 15.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KFH44563.1 - 0.0036 17.3 0.1 0.017 15.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 KFH44563.1 - 0.0052 16.7 0.0 1.1 9.2 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Glyco_transf_21 PF13506.1 KFH44563.1 - 0.0069 15.6 0.2 0.019 14.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 21 ABC_tran PF00005.22 KFH44563.1 - 0.031 14.5 0.0 0.088 13.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.1 KFH44563.1 - 0.048 13.8 0.1 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KFH44563.1 - 0.081 12.4 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2592 PF10766.4 KFH44563.1 - 0.13 11.5 0.6 0.42 9.9 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2592) Chitin_synth_2 PF03142.10 KFH44564.1 - 3.3e-20 71.9 0.5 4.7e-20 71.4 0.4 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 KFH44564.1 - 7e-15 55.2 7.5 1.3e-14 54.3 5.2 1.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KFH44564.1 - 1.7e-10 41.1 0.3 2.9e-10 40.3 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Abhydrolase_3 PF07859.8 KFH44565.1 - 1.9e-43 148.5 0.0 3.1e-43 147.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KFH44565.1 - 2.6e-07 29.7 0.0 7.3e-07 28.2 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 KFH44565.1 - 9.1e-07 28.3 0.0 0.016 14.4 0.0 2.8 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFH44565.1 - 1.2e-05 25.0 0.0 1.7e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KFH44565.1 - 0.014 14.7 0.0 0.15 11.4 0.0 2.4 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Esterase_phd PF10503.4 KFH44565.1 - 0.037 13.2 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase PPR_3 PF13812.1 KFH44567.1 - 2.4e-11 42.9 4.3 0.00021 21.3 0.0 6.7 7 0 0 7 7 7 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 KFH44567.1 - 1.7e-05 24.6 0.5 7.8 6.5 0.0 5.7 6 0 0 6 6 6 3 PPR repeat family PPR PF01535.15 KFH44567.1 - 5.3e-05 22.9 2.0 1.1 9.3 0.0 6.0 6 0 0 6 6 6 1 PPR repeat RNA_pol_I_TF PF04090.7 KFH44568.1 - 0.00024 20.4 0.0 0.001 18.4 0.0 1.8 2 1 0 2 2 2 1 RNA polymerase I specific initiation factor TPR_6 PF13174.1 KFH44568.1 - 0.46 11.0 1.9 7.5 7.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Draxin PF15550.1 KFH44571.1 - 3 7.4 15.1 0.52 9.9 6.4 2.1 2 0 0 2 2 2 0 Draxin Rib_5-P_isom_A PF06026.9 KFH44572.1 - 2.3e-38 131.2 0.0 5e-36 123.6 0.0 2.1 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) dsrm PF00035.20 KFH44573.1 - 4.2e-07 30.4 0.0 8.8e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.1 KFH44573.1 - 4.5e-05 23.4 0.0 0.32 10.9 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KFH44573.1 - 0.0023 18.3 0.0 0.0056 17.1 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease III domain Alpha_GJ PF03229.8 KFH44573.1 - 0.52 10.6 9.1 1.5 9.1 6.3 1.7 1 0 0 1 1 1 0 Alphavirus glycoprotein J Amidohydro_1 PF01979.15 KFH44574.1 - 4.1e-44 151.5 0.0 5.2e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KFH44574.1 - 6.4e-07 28.9 5.3 1e-05 25.0 0.2 2.8 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KFH44574.1 - 1.7e-05 24.5 0.0 5e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 KFH44574.1 - 0.00038 20.5 0.1 0.015 15.3 0.1 2.8 1 1 0 1 1 1 1 Amidohydrolase BSP_II PF05432.6 KFH44574.1 - 0.13 11.5 4.0 0.22 10.7 2.7 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Serglycin PF04360.7 KFH44574.1 - 0.18 11.5 2.3 0.37 10.4 1.6 1.5 1 0 0 1 1 1 0 Serglycin La PF05383.12 KFH44575.1 - 9.2e-13 47.7 0.0 1.7e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 KFH44575.1 - 5.1e-10 38.8 0.2 1e-09 37.9 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH44575.1 - 1.8e-08 34.2 0.0 3.1e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH44575.1 - 2.2e-05 24.1 0.0 4.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FXR1P_C PF12235.3 KFH44575.1 - 4.4 7.3 23.8 0.091 12.8 11.5 1.9 2 0 0 2 2 2 0 Fragile X-related 1 protein C terminal Yip1 PF04893.12 KFH44576.1 - 6.5e-12 45.2 12.9 9.9e-12 44.6 8.9 1.5 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 KFH44576.1 - 0.002 17.7 4.4 0.0032 17.1 3.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) NAD_binding_2 PF03446.10 KFH44577.1 - 5.4e-28 97.8 0.2 7.9e-28 97.3 0.1 1.3 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KFH44577.1 - 5.5e-10 39.3 0.6 9.4e-10 38.6 0.4 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 KFH44577.1 - 5.1e-08 33.2 0.1 1.6e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 KFH44577.1 - 1.7e-07 31.4 0.0 3.2e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_3 PF03447.11 KFH44577.1 - 0.0015 18.9 0.0 0.0038 17.6 0.0 1.7 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 KFH44577.1 - 0.013 15.7 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 KFH44577.1 - 0.018 15.0 0.1 0.075 13.0 0.0 2.0 2 1 0 2 2 2 0 TrkA-N domain adh_short_C2 PF13561.1 KFH44578.1 - 2.3e-21 76.6 0.0 9.9e-21 74.6 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ketoacyl-synt PF00109.21 KFH44578.1 - 2.3e-21 76.4 0.0 5.4e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 KFH44578.1 - 6.8e-18 64.5 0.0 1.6e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 KFH44578.1 - 5.5e-11 42.3 0.5 1.6e-10 40.8 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 KFH44578.1 - 3.7e-06 26.9 0.0 1e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH44578.1 - 0.00041 20.0 0.1 0.0017 18.0 0.0 2.1 2 0 0 2 2 2 1 KR domain DUF619 PF04768.8 KFH44579.1 - 2.4e-51 173.5 0.0 8.5e-51 171.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Mo-co_dimer PF03404.11 KFH44580.1 - 1.5e-56 189.6 0.0 5.5e-56 187.7 0.0 1.9 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 KFH44580.1 - 2.4e-51 173.5 0.0 1.7e-50 170.7 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.19 KFH44580.1 - 4.2e-29 100.5 0.0 8.7e-29 99.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KFH44580.1 - 4.2e-27 94.8 0.0 8.6e-27 93.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 KFH44580.1 - 1.5e-21 75.9 0.0 3.1e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 KFH44580.1 - 0.0027 17.6 0.0 0.04 13.8 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain DUF2173 PF09941.4 KFH44581.1 - 0.24 11.3 2.2 0.26 11.2 0.2 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2173) eIF-5a PF01287.15 KFH44582.1 - 4.8e-21 74.4 1.5 1.1e-20 73.3 1.1 1.6 1 1 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 KFH44582.1 - 0.00036 20.1 0.6 0.00036 20.1 0.4 1.9 2 0 0 2 2 2 1 KOW motif EFP_N PF08207.7 KFH44582.1 - 0.053 13.3 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Yip1 PF04893.12 KFH44583.1 - 1.7e-12 47.1 16.4 1.7e-12 47.1 11.3 1.4 1 1 0 1 1 1 1 Yip1 domain BAR_2 PF10455.4 KFH44584.1 - 4e-57 193.3 0.3 6.1e-57 192.7 0.2 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 KFH44584.1 - 2.5e-17 63.1 0.7 2.2e-16 60.0 0.5 2.2 1 1 0 1 1 1 1 BAR domain MCPVI PF02993.9 KFH44584.1 - 0.0087 16.2 0.6 0.0087 16.2 0.4 1.8 1 1 1 2 2 2 1 Minor capsid protein VI p450 PF00067.17 KFH44585.1 - 3e-52 177.6 0.0 4.5e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 S4 PF01479.20 KFH44586.1 - 1.5e-16 59.5 0.0 2.5e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 KFH44586.1 - 0.057 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 S4 domain DUF1455 PF07306.6 KFH44586.1 - 0.059 13.4 0.2 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1455) BCDHK_Adom3 PF10436.4 KFH44587.1 - 4.3e-42 143.4 0.0 6e-42 142.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KFH44587.1 - 5.6e-15 55.0 0.0 9.5e-14 51.0 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 KFH44587.1 - 0.083 12.6 0.0 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.1 KFH44587.1 - 0.13 11.9 0.0 0.38 10.3 0.0 1.8 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FMN_dh PF01070.13 KFH44588.1 - 5.6e-120 400.4 0.0 7.1e-120 400.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KFH44588.1 - 1.1e-22 79.6 0.0 2.3e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KFH44588.1 - 1.3e-07 30.8 0.0 2.1e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KFH44588.1 - 0.0036 16.2 0.1 0.0073 15.2 0.0 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 KFH44588.1 - 0.0037 16.4 0.1 0.0056 15.8 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 KFH44588.1 - 0.02 14.1 0.5 0.69 9.1 0.0 2.4 1 1 0 2 2 2 0 Histidine biosynthesis protein PLDc PF00614.17 KFH44589.1 - 5.8e-12 44.9 9.5 1.9e-07 30.6 0.1 3.1 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KFH44589.1 - 6.5e-11 42.0 0.0 4.6e-05 23.1 0.0 3.6 3 0 0 3 3 3 3 PLD-like domain tRNA-synt_2 PF00152.15 KFH44591.1 - 1.3e-74 251.0 0.0 2e-74 250.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 KFH44591.1 - 1.1e-13 50.6 0.3 2.2e-13 49.7 0.1 1.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 KFH44591.1 - 1.8e-05 24.5 0.0 3.7e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KFH44591.1 - 0.0055 15.9 0.0 0.42 9.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Peptidase_S8 PF00082.17 KFH44592.1 - 1.6e-46 158.7 6.2 1.7e-46 158.6 3.8 1.4 2 0 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.11 KFH44592.1 - 1.9e-14 53.9 0.1 3.4e-14 53.1 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 adh_short PF00106.20 KFH44593.1 - 3.1e-34 118.3 0.2 4.9e-34 117.6 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH44593.1 - 1.3e-24 87.2 1.2 2.1e-24 86.6 0.8 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH44593.1 - 3.8e-17 62.5 0.1 5.6e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KFH44593.1 - 0.0044 16.7 0.8 0.0072 15.9 0.6 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 KFH44593.1 - 0.03 14.1 1.1 0.051 13.4 0.5 1.5 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KFH44593.1 - 0.057 12.7 0.2 0.098 12.0 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Gly_rich_SFCGS PF14272.1 KFH44593.1 - 0.059 13.2 1.3 0.12 12.2 0.9 1.5 1 0 0 1 1 1 0 Glycine-rich SFCGS MFS_1 PF07690.11 KFH44594.1 - 3.9e-41 140.9 54.6 1.6e-40 138.9 37.8 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1418 PF07214.7 KFH44594.1 - 0.86 9.2 3.7 1.3 8.7 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1418) AT_hook PF02178.14 KFH44595.1 - 9.3e-06 24.7 111.9 0.065 12.9 2.2 12.2 11 0 0 11 11 11 9 AT hook motif Sulfotransfer_3 PF13469.1 KFH44596.1 - 3.8e-06 27.9 0.9 7.3e-06 26.9 0.5 1.6 1 1 0 1 1 1 1 Sulfotransferase family SPX PF03105.14 KFH44597.1 - 0.054 13.2 3.7 0.12 12.1 2.1 1.8 1 1 1 2 2 2 0 SPX domain IncA PF04156.9 KFH44597.1 - 0.061 12.9 11.8 0.19 11.3 0.9 2.2 2 0 0 2 2 2 0 IncA protein Vps5 PF09325.5 KFH44597.1 - 0.4 9.9 13.5 0.52 9.5 0.1 2.9 2 1 1 3 3 3 0 Vps5 C terminal like FimP PF09766.4 KFH44597.1 - 2.5 7.0 10.8 4.4 6.2 7.5 1.3 1 0 0 1 1 1 0 Fms-interacting protein AATase PF07247.7 KFH44598.1 - 2.7e-22 78.9 0.0 1.3e-21 76.7 0.0 1.8 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 KFH44598.1 - 0.00019 20.4 0.3 0.00039 19.3 0.2 1.5 1 1 0 1 1 1 1 Condensation domain DUF2267 PF10025.4 KFH44598.1 - 0.071 13.1 0.1 0.25 11.3 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) MRP-L28 PF09812.4 KFH44599.1 - 0.0061 16.3 0.2 0.013 15.3 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 NST1 PF13945.1 KFH44600.1 - 2.4e-55 187.5 7.3 2.4e-55 187.5 5.1 5.2 2 2 3 5 5 5 1 Salt tolerance down-regulator TPP_enzyme_N PF02776.13 KFH44601.1 - 5.2e-54 182.3 0.0 1.7e-52 177.3 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KFH44601.1 - 2.6e-50 169.9 0.0 7.9e-49 165.1 0.0 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KFH44601.1 - 1.5e-37 128.3 0.3 1.1e-36 125.6 0.1 2.3 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain DUF1680 PF07944.7 KFH44602.1 - 8.2e-138 459.9 1.4 9.4e-138 459.7 0.9 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) C5-epim_C PF06662.8 KFH44602.1 - 0.022 14.0 0.1 7.1 5.8 0.0 2.7 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus Fungal_trans PF04082.13 KFH44604.1 - 5.7e-13 48.3 0.0 1.5e-12 46.9 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH44604.1 - 3.3e-07 30.0 11.1 3.3e-07 30.0 7.7 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 KFH44605.1 - 1.7e-57 194.5 0.0 2.2e-57 194.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH44605.1 - 6.2e-30 104.1 0.0 7.8e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH44605.1 - 3.1e-06 26.3 0.0 0.00021 20.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFH44605.1 - 0.0014 17.7 0.0 0.0022 17.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFH44605.1 - 0.0018 18.0 0.0 0.0033 17.1 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFH44605.1 - 0.023 13.5 0.0 0.04 12.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase UL11 PF11094.3 KFH44605.1 - 0.05 13.4 0.1 0.28 11.0 0.0 2.1 2 0 0 2 2 2 0 Membrane-associated tegument protein DUF4139 PF13598.1 KFH44606.1 - 4.3e-52 177.3 19.0 2.6e-39 135.4 0.3 4.1 2 1 0 3 3 3 2 Domain of unknown function (DUF4139) DUF4140 PF13600.1 KFH44606.1 - 5.7e-10 39.5 5.5 5.7e-10 39.5 3.8 5.2 3 2 1 4 4 4 1 N-terminal domain of unknown function (DUF4140) SET PF00856.23 KFH44608.1 - 2.7e-12 47.2 0.0 9.1e-10 39.0 0.0 2.3 2 0 0 2 2 2 2 SET domain zf-MYND PF01753.13 KFH44608.1 - 0.021 14.6 13.5 0.021 14.6 9.4 2.3 3 0 0 3 3 3 0 MYND finger Pkinase PF00069.20 KFH44609.1 - 1e-52 178.9 0.0 1.6e-52 178.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH44609.1 - 2.2e-23 82.6 0.0 4.7e-23 81.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KFH44609.1 - 0.015 14.0 0.0 0.024 13.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 KFH44609.1 - 0.016 14.1 0.0 0.035 13.0 0.0 1.5 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 KFH44609.1 - 0.037 13.3 0.0 0.11 11.8 0.0 1.8 1 0 0 1 1 1 0 RIO1 family HlyIII PF03006.15 KFH44610.1 - 2.1e-61 207.1 14.5 2.5e-61 206.9 10.1 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.6 KFH44610.1 - 0.045 13.6 0.3 0.25 11.2 0.2 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF962) DUF4231 PF14015.1 KFH44610.1 - 0.14 12.1 3.7 8.7 6.3 0.6 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) DUF3325 PF11804.3 KFH44610.1 - 1.6 8.7 9.1 0.091 12.7 1.0 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3325) Cation_ATPase_C PF00689.16 KFH44610.1 - 5.7 6.4 8.2 1.2 8.6 2.1 2.2 1 1 0 2 2 2 0 Cation transporting ATPase, C-terminus adh_short_C2 PF13561.1 KFH44611.1 - 5.4e-25 88.5 0.0 7.1e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFH44611.1 - 2.2e-23 83.0 1.1 3.1e-23 82.5 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH44611.1 - 2.5e-10 40.3 0.2 4.7e-10 39.4 0.2 1.4 1 1 0 1 1 1 1 KR domain ThiF PF00899.16 KFH44611.1 - 0.018 14.8 0.1 1.1 9.0 0.0 2.3 1 1 0 1 1 1 0 ThiF family Peptidase_M14 PF00246.19 KFH44612.1 - 2.2e-71 240.7 0.0 2.6e-71 240.4 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Apc3 PF12895.2 KFH44613.1 - 0.00044 20.3 0.2 0.0011 19.0 0.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KFH44613.1 - 0.026 14.8 0.3 15 6.0 0.2 2.8 1 1 0 2 2 2 0 Tetratricopeptide repeat Shisa PF13908.1 KFH44614.1 - 0.0007 19.8 0.5 0.0012 19.0 0.3 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator FOLN PF09289.5 KFH44614.1 - 0.037 13.8 0.1 0.11 12.3 0.1 1.8 1 0 0 1 1 1 0 Follistatin/Osteonectin-like EGF domain Tweety PF04906.8 KFH44614.1 - 0.072 11.5 0.1 0.1 11.0 0.1 1.1 1 0 0 1 1 1 0 Tweety Adeno_E3_CR2 PF02439.10 KFH44614.1 - 0.11 12.0 0.4 0.27 10.7 0.3 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF3669 PF12417.3 KFH44615.1 - 5.8e-22 77.2 0.0 1e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Zinc finger protein Lipocalin_2 PF08212.7 KFH44617.1 - 1.1e-18 67.4 0.0 1.3e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain DUF221 PF02714.10 KFH44618.1 - 1.3e-94 316.6 15.5 1.9e-94 316.1 10.7 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KFH44618.1 - 1e-36 125.8 2.2 1e-36 125.8 1.5 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KFH44618.1 - 3e-17 62.8 1.4 4.2e-17 62.4 0.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4463) Sugar_tr PF00083.19 KFH44619.1 - 7.6e-112 374.1 29.2 1e-111 373.7 20.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH44619.1 - 4.9e-24 84.6 44.7 4.9e-15 55.1 12.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glycos_transf_2 PF00535.21 KFH44620.1 - 1e-33 116.3 0.0 1.3e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KFH44620.1 - 4.7e-13 49.4 0.0 7.8e-13 48.7 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 KFH44620.1 - 6.9e-09 35.1 0.0 9.5e-09 34.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KFH44620.1 - 4.7e-07 29.2 0.0 7.3e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.1 KFH44620.1 - 0.087 13.1 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 GalKase_gal_bdg PF10509.4 KFH44621.1 - 6.4e-21 73.3 0.0 1.4e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 KFH44621.1 - 3.8e-13 49.3 2.1 3.8e-13 49.3 1.5 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KFH44621.1 - 1.4e-12 47.5 0.0 5e-12 45.8 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal Sigma70_r4_2 PF08281.7 KFH44621.1 - 0.089 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Cutinase PF01083.17 KFH44622.1 - 4.5e-40 137.2 0.0 6.2e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 KFH44622.1 - 7.5e-08 32.0 0.0 1.1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain DUF3079 PF11278.3 KFH44622.1 - 0.0086 15.5 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3079) MFS_1 PF07690.11 KFH44625.1 - 9.9e-13 47.5 37.5 9.9e-13 47.5 26.0 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily PUA PF01472.15 KFH44626.1 - 1.2e-10 40.9 0.2 1e-05 25.1 0.0 2.2 2 0 0 2 2 2 2 PUA domain p450 PF00067.17 KFH44627.1 - 8.9e-44 149.7 0.0 1.5e-43 149.0 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Ras PF00071.17 KFH44632.1 - 1.2e-44 151.5 0.0 4.9e-37 126.8 0.0 2.0 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KFH44632.1 - 1.8e-15 57.4 0.0 2.8e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 KFH44632.1 - 0.051 13.0 0.1 2.9 7.3 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.1 KFH44632.1 - 0.079 12.9 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain RRM_1 PF00076.17 KFH44633.1 - 0.0092 15.5 0.0 0.082 12.5 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.10 KFH44633.1 - 0.13 12.1 0.1 0.28 11.1 0.0 1.5 2 0 0 2 2 2 0 Smg-4/UPF3 family Inhibitor_I78 PF11720.3 KFH44638.1 - 2e-11 43.4 0.0 2.6e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 KFH44638.1 - 7.4e-05 22.8 0.3 9.9e-05 22.4 0.2 1.4 1 1 0 1 1 1 1 Potato inhibitor I family Thiol-ester_cl PF10569.4 KFH44639.1 - 0.52 9.5 4.5 4.6 6.5 0.2 2.4 2 0 0 2 2 2 0 Alpha-macro-globulin thiol-ester bond-forming region TMA7 PF09072.5 KFH44641.1 - 8.8e-25 86.9 19.2 9.7e-25 86.8 13.3 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 ADH_zinc_N PF00107.21 KFH44642.1 - 5.8e-19 67.9 1.8 7e-19 67.6 0.2 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFH44642.1 - 5.6e-18 64.6 0.0 1.1e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.14 KFH44642.1 - 0.003 16.7 0.0 0.0057 15.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain WD40 PF00400.27 KFH44643.1 - 7.6e-06 25.6 3.4 1.6 8.7 0.1 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat zf-C2H2_4 PF13894.1 KFH44644.1 - 0.056 13.7 0.6 0.056 13.7 0.4 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KFH44644.1 - 1.6 9.1 15.6 0.31 11.4 1.0 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type AA_permease PF00324.16 KFH44645.1 - 4.4e-54 183.6 18.7 2e-53 181.4 13.0 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFH44645.1 - 1.1e-22 80.1 18.8 1.7e-22 79.5 13.1 1.2 1 0 0 1 1 1 1 Amino acid permease Na_H_Exchanger PF00999.16 KFH44646.1 - 6.9e-31 107.1 14.2 9.1e-31 106.7 9.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 KFH44646.1 - 0.003 17.4 0.9 0.012 15.5 0.1 2.5 2 0 0 2 2 2 1 YrhC-like protein HeH PF12949.2 KFH44647.1 - 0.11 12.0 0.1 14 5.2 0.0 2.5 2 0 0 2 2 2 0 HeH/LEM domain AIM24 PF01987.12 KFH44648.1 - 3.3e-43 147.6 0.6 3.7e-43 147.4 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 RR_TM4-6 PF06459.7 KFH44649.1 - 0.39 10.5 7.8 0.52 10.1 5.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Velvet PF11754.3 KFH44650.1 - 5.5e-63 212.2 0.0 9.3e-63 211.5 0.0 1.4 1 0 0 1 1 1 1 Velvet factor Peptidase_C12 PF01088.16 KFH44651.1 - 3.5e-56 189.7 0.0 4.3e-56 189.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Arylsulfotran_2 PF14269.1 KFH44652.1 - 8.7e-51 172.8 0.5 1.2e-50 172.3 0.3 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KFH44652.1 - 3.6e-15 55.4 0.1 9.3e-15 54.0 0.0 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) FGGY_C PF02782.11 KFH44653.1 - 7.7e-49 166.0 0.5 1.1e-48 165.4 0.3 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KFH44653.1 - 7.1e-25 87.7 3.7 4.6e-23 81.8 0.3 3.7 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 KFH44653.1 - 0.001 18.4 0.5 0.027 13.7 0.0 2.2 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family MOZART1 PF12554.3 KFH44654.1 - 4.9e-26 89.9 0.9 5.8e-26 89.6 0.6 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated MOZART2 PF12926.2 KFH44654.1 - 0.03 13.8 0.0 0.033 13.7 0.0 1.1 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated WXG100 PF06013.7 KFH44654.1 - 0.098 12.6 1.7 0.6 10.1 0.2 2.0 2 0 0 2 2 2 0 Proteins of 100 residues with WXG HTH_3 PF01381.17 KFH44654.1 - 0.11 12.3 2.1 33 4.4 0.5 3.0 3 0 0 3 3 3 0 Helix-turn-helix HTH_26 PF13443.1 KFH44654.1 - 0.14 12.3 0.2 7.3 6.8 0.1 2.1 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain UPF0181 PF03701.9 KFH44654.1 - 0.85 8.9 4.8 1.5 8.2 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) PMT PF02366.13 KFH44656.1 - 2.8e-84 282.3 15.5 2.8e-84 282.3 10.8 2.3 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KFH44656.1 - 2.7e-37 128.1 0.6 3.7e-37 127.7 0.4 1.2 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.1 KFH44656.1 - 2e-06 27.7 9.0 2e-06 27.7 6.2 2.5 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Shugoshin_C PF07557.6 KFH44657.1 - 4.7e-10 38.7 5.1 4.7e-10 38.7 3.5 2.7 2 0 0 2 2 2 1 Shugoshin C terminus Shugoshin_N PF07558.6 KFH44657.1 - 1e-08 34.7 5.4 1e-08 34.7 3.8 2.0 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region AKNA PF12443.3 KFH44657.1 - 0.005 16.8 0.3 0.018 15.0 0.2 1.9 1 0 0 1 1 1 1 AT-hook-containing transcription factor Mod_r PF07200.8 KFH44657.1 - 0.016 15.1 1.9 0.016 15.1 1.3 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein OB_NTP_bind PF07717.11 KFH44659.1 - 3.2e-24 84.9 0.0 6.1e-24 84.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KFH44659.1 - 1.8e-20 72.8 0.5 4.3e-20 71.6 0.0 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KFH44659.1 - 3.3e-11 42.8 0.0 8e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KFH44659.1 - 0.00044 20.3 0.0 0.0014 18.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 KFH44659.1 - 0.02 14.3 1.2 0.19 11.2 0.9 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase cobW PF02492.14 KFH44659.1 - 0.026 13.9 0.3 0.91 8.9 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 KFH44659.1 - 0.038 12.9 0.0 0.074 11.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 KFH44659.1 - 0.11 11.6 2.5 0.47 9.5 0.0 2.8 2 1 1 3 3 3 0 Zeta toxin AAA_29 PF13555.1 KFH44659.1 - 0.14 11.6 0.0 0.41 10.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 KFH44659.1 - 0.69 10.2 5.1 0.35 11.1 0.4 2.3 2 1 0 2 2 2 0 AAA domain TetR_C_7 PF14246.1 KFH44660.1 - 0.016 15.4 0.1 0.034 14.3 0.1 1.5 1 0 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal region F-box PF00646.28 KFH44660.1 - 0.033 13.8 0.0 0.3 10.7 0.0 2.4 2 0 0 2 2 2 0 F-box domain CUE PF02845.11 KFH44661.1 - 1.3e-13 50.0 0.0 2.4e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 CUE domain Mcm10 PF09332.6 KFH44661.1 - 0.096 12.0 8.6 0.042 13.1 0.8 2.3 2 0 0 2 2 2 0 Mcm10 replication factor YtxH PF12732.2 KFH44661.1 - 0.36 11.2 4.5 51 4.3 3.7 2.4 2 0 0 2 2 2 0 YtxH-like protein TPPK_C PF12555.3 KFH44662.1 - 8.3 6.2 7.3 6.1 6.6 0.3 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal PITH PF06201.8 KFH44664.1 - 7.7e-45 152.3 0.0 9.3e-45 152.1 0.0 1.1 1 0 0 1 1 1 1 PITH domain SNARE PF05739.14 KFH44665.1 - 4.5e-10 39.0 1.2 6.3e-10 38.6 0.8 1.2 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 KFH44665.1 - 0.0008 18.9 0.0 0.0008 18.9 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF4131 PF13567.1 KFH44666.1 - 8.6 5.7 9.3 1.5 8.2 2.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Ribosomal_L3 PF00297.17 KFH44667.1 - 1.8e-33 116.0 1.7 1e-32 113.6 1.2 2.0 1 1 0 1 1 1 1 Ribosomal protein L3 Glu_synthase PF01645.12 KFH44668.1 - 8.4e-159 528.3 0.0 1.6e-158 527.4 0.0 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase GATase_2 PF00310.16 KFH44668.1 - 6.5e-137 456.0 0.0 9e-137 455.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 KFH44668.1 - 1.9e-114 381.7 0.0 3.4e-114 380.9 0.0 1.3 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 KFH44668.1 - 1e-66 223.8 1.8 2e-66 222.8 1.3 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 KFH44668.1 - 1.9e-22 78.9 0.0 6.8e-22 77.1 0.0 2.0 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 KFH44668.1 - 1.1e-16 61.3 0.0 3.4e-16 59.7 0.0 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFH44668.1 - 3.4e-10 40.3 0.3 0.00088 19.3 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFH44668.1 - 4.7e-09 36.1 0.0 1.9e-08 34.2 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KFH44668.1 - 1.4e-08 34.9 0.0 6.6e-05 23.2 0.0 3.0 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KFH44668.1 - 1.4e-06 27.7 0.1 2.9e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 KFH44668.1 - 7.7e-06 25.0 0.6 8e-05 21.6 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KFH44668.1 - 1.2e-05 24.0 0.1 2.7e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 KFH44668.1 - 0.00016 20.6 0.1 0.0004 19.3 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 KFH44668.1 - 0.00018 20.7 0.1 0.00034 19.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KFH44668.1 - 0.0009 19.4 1.0 1.1 9.5 0.1 2.8 2 0 0 2 2 2 2 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 KFH44668.1 - 0.0016 18.0 0.1 0.051 13.1 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 KFH44668.1 - 0.0029 16.7 0.0 0.006 15.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FMO-like PF00743.14 KFH44668.1 - 0.0049 15.1 0.2 1.2 7.1 0.0 2.8 2 1 1 3 3 3 1 Flavin-binding monooxygenase-like Thi4 PF01946.12 KFH44668.1 - 0.0069 15.4 0.0 0.023 13.8 0.0 1.9 1 0 0 1 1 1 1 Thi4 family NAD_Gly3P_dh_N PF01210.18 KFH44668.1 - 0.0094 15.6 0.1 0.032 13.9 0.0 1.9 2 0 0 2 2 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GATase_6 PF13522.1 KFH44668.1 - 0.05 13.5 0.1 0.94 9.4 0.0 2.4 2 0 0 2 2 2 0 Glutamine amidotransferase domain F420_oxidored PF03807.12 KFH44668.1 - 0.073 13.5 0.0 1.1 9.7 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_9 PF13454.1 KFH44668.1 - 0.11 12.2 0.0 0.4 10.4 0.0 2.0 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KFH44668.1 - 0.12 11.3 0.1 1.3 7.8 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.14 KFH44668.1 - 0.13 11.4 0.1 3.7 6.6 0.0 2.7 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 KFH44668.1 - 0.13 11.6 0.1 0.5 9.7 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA AdoHcyase_NAD PF00670.16 KFH44668.1 - 0.16 11.8 0.9 35 4.1 0.1 3.1 2 1 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GIDA PF01134.17 KFH44668.1 - 0.25 10.1 2.4 0.22 10.3 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 KFH44668.1 - 0.49 10.0 1.8 0.48 10.0 0.0 1.9 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain His_Phos_2 PF00328.17 KFH44669.1 - 6.9e-16 58.4 0.2 4.4e-14 52.5 0.0 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) DUF3425 PF11905.3 KFH44671.1 - 4.1e-33 114.1 1.2 4.1e-33 114.1 0.8 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) Med3 PF11593.3 KFH44671.1 - 0.0073 15.5 1.9 15 4.6 4.2 2.4 2 1 0 2 2 2 2 Mediator complex subunit 3 fungal bZIP_1 PF00170.16 KFH44671.1 - 0.019 14.9 14.0 0.091 12.7 9.7 2.1 1 1 0 1 1 1 0 bZIP transcription factor Rrn6 PF10214.4 KFH44672.1 - 3e-50 171.1 0.0 2e-49 168.4 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor E1-E2_ATPase PF00122.15 KFH44673.1 - 9.3e-64 214.5 4.7 2.1e-63 213.4 3.3 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KFH44673.1 - 4.7e-23 82.7 0.0 9.3e-23 81.7 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFH44673.1 - 3.6e-13 50.0 0.0 1e-12 48.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFH44673.1 - 9.1e-10 37.8 0.0 2.2e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KFH44673.1 - 0.0088 15.6 0.3 0.018 14.6 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFH44673.1 - 0.017 15.0 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit DUF2614 PF11023.3 KFH44673.1 - 4.7 7.0 8.6 0.25 11.1 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2614) DUF2012 PF09430.5 KFH44674.1 - 3e-20 72.2 0.0 3.9e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) SKG6 PF08693.5 KFH44675.1 - 1.5e-06 27.4 2.9 1.5e-06 27.4 2.0 1.7 2 0 0 2 2 2 1 Transmembrane alpha-helix domain TMEM154 PF15102.1 KFH44675.1 - 0.0042 16.8 0.0 0.014 15.0 0.0 1.9 1 1 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.1 KFH44675.1 - 0.017 14.5 0.0 0.041 13.3 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) DUF1191 PF06697.7 KFH44675.1 - 0.14 10.9 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) CcmD PF04995.9 KFH44675.1 - 0.17 11.6 0.4 0.29 10.9 0.3 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF1049 PF06305.6 KFH44675.1 - 0.17 11.3 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) MARVEL PF01284.18 KFH44676.1 - 9.1e-11 41.7 10.1 1.2e-10 41.4 7.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain zinc_ribbon_6 PF14599.1 KFH44677.1 - 4.8e-26 90.3 0.1 4.8e-26 90.3 0.1 4.0 4 1 0 5 5 5 1 Zinc-ribbon zf-CHY PF05495.7 KFH44677.1 - 3.4e-18 65.5 18.9 3.4e-18 65.5 13.1 4.3 3 1 1 4 4 4 1 CHY zinc finger zf-RING_2 PF13639.1 KFH44677.1 - 9.2e-09 34.9 9.7 9.2e-09 34.9 6.7 4.6 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFH44677.1 - 9.8e-08 31.9 8.2 9.8e-08 31.9 5.7 5.5 4 2 2 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFH44677.1 - 2.6e-07 30.1 9.3 2.6e-07 30.1 6.4 5.8 2 2 3 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFH44677.1 - 5.7e-07 29.1 9.1 5.7e-07 29.1 6.3 6.2 2 1 4 6 6 6 1 zinc-RING finger domain WD40 PF00400.27 KFH44679.1 - 1.4e-08 34.2 12.4 0.046 13.6 0.1 6.7 7 0 0 7 7 7 3 WD domain, G-beta repeat Nup160 PF11715.3 KFH44679.1 - 0.00055 18.2 1.0 1 7.3 0.0 2.9 2 1 1 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.6 KFH44679.1 - 0.028 14.1 0.4 3.5 7.2 0.0 3.0 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Metallophos_2 PF12850.2 KFH44680.1 - 5e-13 49.1 0.0 6.3e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KFH44680.1 - 0.027 13.8 0.1 0.15 11.4 0.0 2.0 1 1 1 2 2 2 0 Calcineurin-like phosphoesterase NUC173 PF08161.7 KFH44681.1 - 2.3e-78 262.1 0.2 3.1e-76 255.1 0.0 3.4 3 0 0 3 3 3 1 NUC173 domain HEAT PF02985.17 KFH44681.1 - 0.0029 17.5 1.4 0.83 9.9 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.1 KFH44681.1 - 0.015 15.5 7.5 2 8.7 0.4 4.9 5 1 0 5 5 5 0 HEAT repeats Vac14_Fab1_bd PF12755.2 KFH44681.1 - 0.032 14.5 0.3 27 5.2 0.0 3.8 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Rsbr_N PF08678.5 KFH44681.1 - 0.067 13.0 1.1 7.2 6.5 0.0 3.3 3 0 0 3 3 3 0 Rsbr N terminal COesterase PF00135.23 KFH44682.1 - 1.9e-67 228.1 0.0 3.3e-67 227.4 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFH44682.1 - 1.5e-05 24.6 3.1 2.7e-05 23.8 0.2 2.6 2 2 0 2 2 2 1 alpha/beta hydrolase fold Nic96 PF04097.9 KFH44683.1 - 1e-192 641.5 0.0 1.3e-192 641.2 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.1 KFH44683.1 - 2.4e-11 43.8 110.3 6.2e-06 26.4 54.3 4.5 2 1 1 3 3 3 2 Nucleoporin FG repeat region DASH_Dad2 PF08654.5 KFH44684.1 - 1.1e-33 115.2 0.3 1.8e-33 114.5 0.2 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad2 Seryl_tRNA_N PF02403.17 KFH44684.1 - 0.082 12.9 0.3 0.082 12.9 0.2 1.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FH2 PF02181.18 KFH44684.1 - 0.083 11.7 0.2 0.1 11.4 0.1 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain RRM_1 PF00076.17 KFH44685.1 - 7.9e-07 28.6 0.0 1.4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH44685.1 - 1.4e-06 28.0 0.0 2.4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH44685.1 - 1.2e-05 25.2 0.0 2.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 KFH44685.1 - 0.00021 21.4 0.0 0.00079 19.6 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase II-binding domain. Ras PF00071.17 KFH44686.1 - 7.2e-51 171.7 0.0 1.5e-39 134.9 0.0 2.0 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KFH44686.1 - 1.1e-16 61.4 0.0 4.2e-16 59.5 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFH44686.1 - 1.3e-11 44.0 0.0 4.5e-11 42.3 0.1 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFH44686.1 - 6.1e-07 29.0 0.0 3.3e-06 26.6 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFH44686.1 - 1.2e-06 27.8 0.0 2.4e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFH44686.1 - 6.3e-05 22.9 0.0 0.00013 21.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KFH44686.1 - 0.007 16.5 0.0 0.02 15.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFH44686.1 - 0.063 13.2 0.1 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.1 KFH44686.1 - 0.066 12.6 0.1 7.1 5.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 KFH44686.1 - 0.071 12.5 0.0 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 KFH44686.1 - 0.094 12.1 0.0 0.35 10.2 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain ABC_tran PF00005.22 KFH44686.1 - 0.12 12.6 0.1 0.74 10.1 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Mito_carr PF00153.22 KFH44687.1 - 2.5e-29 100.8 5.2 5.8e-13 48.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2293 PF10056.4 KFH44688.1 - 6.3e-24 83.7 0.7 2e-23 82.1 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) CHZ PF09649.5 KFH44689.1 - 2.2e-15 55.5 0.6 2.2e-15 55.5 0.4 2.4 3 0 0 3 3 3 1 Histone chaperone domain CHZ Ank_2 PF12796.2 KFH44690.1 - 1.4e-50 169.5 9.0 1.8e-16 60.2 0.4 5.0 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFH44690.1 - 6.9e-33 112.4 9.0 3.4e-10 40.1 0.0 6.5 3 2 5 8 8 8 6 Ankyrin repeats (many copies) SPX PF03105.14 KFH44690.1 - 3.7e-30 105.6 10.8 1e-16 61.5 2.4 2.4 1 1 1 2 2 2 2 SPX domain Ank PF00023.25 KFH44690.1 - 6.7e-29 98.2 14.4 1.6e-06 27.5 0.0 7.9 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.1 KFH44690.1 - 2e-25 88.2 14.0 5.3e-07 29.6 0.2 7.6 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFH44690.1 - 7.8e-21 72.0 10.9 9.7e-05 22.2 0.0 8.0 9 0 0 9 9 9 4 Ankyrin repeat GDPD PF03009.12 KFH44690.1 - 1.8e-07 30.9 0.0 8.8e-07 28.6 0.0 2.2 2 1 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Apc15p PF05841.6 KFH44691.1 - 3.4e-21 76.2 1.4 3.4e-20 73.0 0.9 2.3 1 1 0 1 1 1 1 Apc15p protein Coa1 PF08695.5 KFH44692.1 - 3e-40 136.3 0.0 3.8e-40 136.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Cyclin PF08613.6 KFH44693.1 - 3.9e-28 98.7 0.0 6.9e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KFH44693.1 - 0.00034 20.1 0.0 0.00055 19.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain VTC PF09359.5 KFH44694.1 - 2.1e-92 309.1 1.2 3.6e-92 308.3 0.8 1.4 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 KFH44694.1 - 2.3e-17 63.6 17.5 4.1e-09 36.6 2.3 3.7 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 KFH44694.1 - 1.5e-08 34.7 2.2 1.5e-08 34.7 1.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Cob_adeno_trans PF01923.13 KFH44694.1 - 0.0018 18.1 0.3 1.4 8.7 0.1 2.6 2 0 0 2 2 2 2 Cobalamin adenosyltransferase Bax1-I PF01027.15 KFH44694.1 - 0.038 13.5 1.1 0.059 12.9 0.8 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Spindle_Spc25 PF08234.7 KFH44695.1 - 2.1e-22 78.8 0.1 4.1e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 TMV_coat PF00721.16 KFH44695.1 - 0.016 15.1 2.3 0.033 14.1 1.6 1.6 1 0 0 1 1 1 0 Virus coat protein (TMV like) UDPG_MGDP_dh_N PF03721.9 KFH44695.1 - 0.075 12.4 0.2 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Atg14 PF10186.4 KFH44695.1 - 0.12 11.2 8.5 0.22 10.4 5.9 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF848 PF05852.6 KFH44695.1 - 1.5 8.6 12.4 0.31 10.8 5.5 2.1 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) AAA_23 PF13476.1 KFH44695.1 - 1.7 8.9 6.1 1.1 9.5 3.1 1.4 2 0 0 2 2 2 0 AAA domain FUSC PF04632.7 KFH44695.1 - 2 6.7 6.1 2.4 6.4 4.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DegS PF05384.6 KFH44695.1 - 3.9 6.6 16.1 0.53 9.4 6.5 2.5 2 1 1 3 3 3 0 Sensor protein DegS DUF4140 PF13600.1 KFH44695.1 - 5.7 7.4 11.1 1.5 9.3 4.7 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Arm PF00514.18 KFH44696.1 - 3.1e-09 36.2 8.7 0.0045 16.7 0.0 6.4 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 KFH44696.1 - 0.00029 20.6 16.3 0.12 12.5 0.1 7.1 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.1 KFH44696.1 - 0.01 16.1 15.4 0.32 11.3 0.0 6.3 6 2 1 7 7 7 3 HEAT repeats HEAT_EZ PF13513.1 KFH44696.1 - 6.9 7.3 25.3 2.2 8.9 0.0 7.6 8 2 1 9 9 9 0 HEAT-like repeat Acetyltransf_1 PF00583.19 KFH44698.1 - 3.1e-17 62.3 0.2 5e-17 61.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KFH44698.1 - 2.6e-08 33.9 0.2 5.1e-08 33.0 0.1 1.7 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KFH44698.1 - 2.1e-07 31.0 0.0 3.2e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFH44698.1 - 2.3e-07 30.4 0.0 3.8e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 KFH44698.1 - 0.0013 18.8 0.0 0.0017 18.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFH44698.1 - 0.011 15.6 0.0 0.03 14.1 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KFH44698.1 - 0.02 14.7 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase MOZ_SAS PF01853.13 KFH44698.1 - 0.034 13.3 0.0 0.056 12.6 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family Acetyltransf_4 PF13420.1 KFH44698.1 - 0.054 13.4 0.0 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MatE PF01554.13 KFH44699.1 - 1.4e-05 24.8 13.5 0.0015 18.1 0.5 3.4 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 KFH44699.1 - 0.0035 17.1 0.4 0.0035 17.1 0.3 4.1 4 1 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain TIG PF01833.19 KFH44700.1 - 1.2e-13 50.8 1.0 3.1e-13 49.5 0.7 1.8 1 0 0 1 1 1 1 IPT/TIG domain Ank PF00023.25 KFH44700.1 - 3.3e-12 45.5 1.4 3.6e-05 23.3 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KFH44700.1 - 1.1e-11 44.9 0.1 2.3e-11 43.8 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFH44700.1 - 3e-10 39.9 2.0 4e-08 33.2 0.1 3.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFH44700.1 - 3.1e-08 33.8 0.6 3.4e-06 27.4 0.2 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFH44700.1 - 1.6e-07 30.8 0.4 0.037 14.2 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat DUF3317 PF11779.3 KFH44700.1 - 0.83 9.1 2.3 2.5 7.5 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3317) Cys_Met_Meta_PP PF01053.15 KFH44701.1 - 2.3e-150 500.2 0.0 2.6e-150 500.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KFH44701.1 - 3.4e-13 49.3 0.9 4.8e-13 48.8 0.1 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 KFH44701.1 - 1.7e-09 37.1 0.0 3.7e-09 36.0 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KFH44701.1 - 2.3e-07 29.8 0.2 3.5e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KFH44701.1 - 1.1e-06 27.9 0.0 2.5e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 KFH44701.1 - 0.00014 20.3 0.2 0.00019 19.8 0.1 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase SLA_LP_auto_ag PF05889.8 KFH44701.1 - 0.031 12.7 0.0 0.044 12.2 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) GDC-P PF02347.11 KFH44701.1 - 0.083 11.5 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein AMP-binding PF00501.23 KFH44702.1 - 1.7e-77 260.5 0.0 2.1e-77 260.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Citrate_synt PF00285.16 KFH44704.1 - 1.5e-102 342.9 0.0 1.8e-102 342.6 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 KFH44704.1 - 0.013 14.9 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 Eclosion hormone Choline_transpo PF04515.7 KFH44705.1 - 5.1e-17 61.6 30.8 3e-15 55.8 11.9 3.2 3 0 0 3 3 3 2 Plasma-membrane choline transporter Rad52_Rad22 PF04098.10 KFH44706.1 - 2.4e-59 199.4 0.0 3.4e-59 198.9 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein DSBA PF01323.15 KFH44708.1 - 7.1e-15 55.0 0.8 5.2e-14 52.2 0.0 1.9 2 0 0 2 2 2 1 DSBA-like thioredoxin domain Cyt-b5 PF00173.23 KFH44709.1 - 5.5e-15 54.9 0.0 6.4e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain UQ_con PF00179.21 KFH44710.1 - 1.5e-46 157.2 0.0 1.7e-46 157.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFH44710.1 - 0.0019 17.9 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFH44710.1 - 0.04 13.8 0.3 0.066 13.1 0.2 1.6 1 1 0 1 1 1 0 RWD domain Ribosomal_L44 PF00935.14 KFH44711.1 - 3.7e-34 116.5 13.6 5.2e-34 116.0 9.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 GFA PF04828.9 KFH44712.1 - 5.5e-23 80.7 0.0 8e-23 80.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 KFH44712.1 - 0.12 12.0 0.1 0.12 12.0 0.0 2.6 3 0 0 3 3 3 0 Nudix N-terminal zf-C2H2_4 PF13894.1 KFH44713.1 - 1.3e-08 34.5 22.8 0.00017 21.6 2.4 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KFH44713.1 - 6.4e-07 29.3 21.9 0.002 18.3 3.4 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFH44713.1 - 1.1 9.6 22.1 1.2 9.5 1.9 4.4 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFH44713.1 - 7.8 6.7 14.9 6 7.1 2.6 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFH44713.1 - 9.2 6.6 17.2 0.75 10.0 0.1 4.2 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Porin_3 PF01459.17 KFH44714.1 - 5.3e-60 203.0 2.9 2.1e-59 201.0 2.0 1.8 1 1 0 1 1 1 1 Eukaryotic porin PRNT PF15174.1 KFH44715.1 - 0.058 13.0 0.3 0.08 12.6 0.2 1.2 1 0 0 1 1 1 0 Prion-related protein testis-specific DivIC PF04977.10 KFH44716.1 - 0.00092 18.6 0.5 0.0021 17.5 0.3 1.6 1 0 0 1 1 1 1 Septum formation initiator TPR_2 PF07719.12 KFH44716.1 - 0.039 13.8 0.0 0.15 12.0 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat DASH_Spc19 PF08287.6 KFH44716.1 - 0.12 12.0 2.0 1.7 8.2 0.7 2.3 2 0 0 2 2 2 0 Spc19 Phosphoprotein PF00922.12 KFH44717.1 - 0.037 13.2 0.1 0.074 12.2 0.0 1.4 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein zf-LYAR PF08790.6 KFH44717.1 - 0.081 12.6 1.4 15 5.4 0.0 3.7 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-C2H2_4 PF13894.1 KFH44717.1 - 0.41 11.0 22.6 0.29 11.5 0.5 4.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KFH44717.1 - 2.4 8.7 15.0 16 6.1 0.3 4.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type AIM24 PF01987.12 KFH44718.1 - 8.6e-46 156.1 0.1 1e-45 155.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Ten1 PF12658.2 KFH44719.1 - 2.9e-31 107.8 0.0 3.2e-31 107.6 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.1 KFH44719.1 - 1.6e-05 24.4 0.0 2.1e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit DUF3433 PF11915.3 KFH44720.1 - 1.6e-46 156.4 7.9 1.4e-26 92.5 1.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) MarR PF01047.17 KFH44722.1 - 0.046 13.4 2.2 0.072 12.8 1.5 1.3 1 0 0 1 1 1 0 MarR family Ureidogly_hydro PF04115.7 KFH44723.1 - 2.1e-49 167.0 0.0 2.6e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate hydrolase DUF3186 PF11382.3 KFH44725.1 - 0.018 14.1 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) Tubulin_C PF03953.12 KFH44725.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Tubulin C-terminal domain ORMDL PF04061.9 KFH44727.1 - 5e-60 200.9 5.2 6e-60 200.7 3.6 1.1 1 0 0 1 1 1 1 ORMDL family Cytochrom_B561 PF03188.11 KFH44730.1 - 1.9e-08 34.2 11.6 1.9e-08 34.2 8.0 1.8 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 KFH44730.1 - 2.7e-05 23.7 4.4 2.7e-05 23.7 3.1 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Acyl_transf_3 PF01757.17 KFH44730.1 - 0.88 8.3 19.7 12 4.6 13.2 2.1 1 1 0 1 1 1 0 Acyltransferase family DoxX_3 PF13781.1 KFH44730.1 - 1.1 9.7 9.0 0.25 11.7 0.8 2.6 2 0 0 2 2 2 0 DoxX-like family MFS_1 PF07690.11 KFH44731.1 - 7.8e-33 113.6 55.4 1.8e-28 99.3 25.7 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH44731.1 - 9.1e-16 57.4 29.7 3.2e-15 55.6 20.6 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3278 PF11683.3 KFH44731.1 - 0.039 13.9 5.3 1.6 8.7 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) DUF3951 PF13131.1 KFH44731.1 - 2.9 7.7 7.5 0.68 9.7 2.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) zf-PHD-like PF15446.1 KFH44732.1 - 2.7e-70 235.1 10.7 5.3e-70 234.2 7.4 1.5 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 KFH44732.1 - 2.2e-54 184.2 0.0 3.7e-54 183.5 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFH44732.1 - 4.4e-15 55.3 0.0 3.2e-14 52.5 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KFH44732.1 - 5e-10 38.6 0.6 1.1e-09 37.5 0.4 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.19 KFH44732.1 - 2.1e-08 33.6 1.2 1.1e-05 25.0 0.2 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 KFH44732.1 - 1.3e-06 27.9 8.9 1.3e-06 27.9 6.1 3.0 3 0 0 3 3 3 2 PHD-finger DEAD PF00270.24 KFH44732.1 - 0.00011 21.7 0.0 0.00023 20.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KFH44732.1 - 0.00012 22.0 0.0 0.00028 20.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PHD_2 PF13831.1 KFH44732.1 - 0.41 10.0 11.4 0.03 13.6 3.7 2.3 2 0 0 2 2 2 0 PHD-finger Formyl_trans_N PF00551.14 KFH44733.1 - 1.9e-17 63.3 0.0 2.7e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Kinesin PF00225.18 KFH44735.1 - 3.8e-112 374.3 0.1 3.8e-112 374.3 0.1 1.6 2 0 0 2 2 2 1 Kinesin motor domain DUF3694 PF12473.3 KFH44735.1 - 6.9e-44 148.9 1.0 1.3e-43 147.9 0.0 2.0 2 0 0 2 2 2 1 Kinesin protein FHA PF00498.21 KFH44735.1 - 9.2e-05 22.4 0.0 0.0012 18.9 0.0 2.9 3 0 0 3 3 3 1 FHA domain KIF1B PF12423.3 KFH44735.1 - 9.2e-05 22.3 0.4 0.00026 20.9 0.3 1.9 1 0 0 1 1 1 1 Kinesin protein 1B PH PF00169.24 KFH44735.1 - 0.00016 21.8 0.0 0.00046 20.3 0.0 1.9 1 0 0 1 1 1 1 PH domain Ribosomal_S2 PF00318.15 KFH44735.1 - 3.5 6.8 6.2 0.33 10.1 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein S2 LIM PF00412.17 KFH44736.1 - 1.9e-20 72.6 22.1 4.4e-11 42.6 2.5 3.0 3 0 0 3 3 3 2 LIM domain AMP-binding PF00501.23 KFH44736.1 - 0.14 10.5 0.0 0.2 9.9 0.0 1.1 1 0 0 1 1 1 0 AMP-binding enzyme Cyt-b5 PF00173.23 KFH44738.1 - 4e-20 71.3 0.2 4.4e-20 71.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.3 KFH44738.1 - 0.062 13.2 0.0 0.075 12.9 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit H MRC1 PF09444.5 KFH44739.1 - 1.1e-40 139.2 19.1 1.1e-40 139.2 13.3 7.9 5 3 3 9 9 9 1 MRC1-like domain Cut8_C PF08559.5 KFH44740.1 - 6.2e-44 149.2 0.0 8.5e-44 148.8 0.0 1.2 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 KFH44740.1 - 6.6e-17 61.0 1.3 1.7e-16 59.6 0.9 1.8 1 0 0 1 1 1 1 Cut8 dimerisation domain Cut8_N PF14482.1 KFH44740.1 - 2e-06 27.7 2.5 3.7e-06 26.8 1.8 1.5 1 0 0 1 1 1 1 Cut8 proteasome-binding domain Exo_endo_phos_2 PF14529.1 KFH44740.1 - 0.098 12.2 0.2 0.19 11.3 0.2 1.5 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase ABC1 PF03109.11 KFH44741.1 - 2.2e-31 108.3 0.1 4e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 ABC1 family UCR_Fe-S_N PF10399.4 KFH44741.1 - 0.004 16.2 1.1 0.013 14.6 0.8 1.8 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal RRM_6 PF14259.1 KFH44742.1 - 9.1e-20 70.4 0.0 6.1e-10 38.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFH44742.1 - 3.9e-19 68.0 0.6 1.2e-11 44.0 0.1 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH44742.1 - 0.0011 18.8 0.1 0.39 10.6 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFH44742.1 - 0.0046 16.7 0.3 0.0046 16.7 0.2 2.6 3 0 0 3 3 3 1 RNA binding motif Glypican PF01153.14 KFH44742.1 - 0.016 13.8 0.1 0.039 12.5 0.1 1.5 1 0 0 1 1 1 0 Glypican Nup35_RRM_2 PF14605.1 KFH44742.1 - 0.052 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif TPR_12 PF13424.1 KFH44743.1 - 6.3e-07 29.2 0.2 0.046 13.6 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFH44743.1 - 1.3e-06 27.9 1.1 0.16 11.6 0.2 3.7 3 1 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 KFH44743.1 - 0.0003 20.4 4.5 0.0056 16.4 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFH44743.1 - 0.00048 19.6 0.2 0.42 10.3 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat Pex19 PF04614.7 KFH44744.1 - 5.4e-73 245.6 9.7 5.4e-73 245.6 6.7 2.0 1 1 1 2 2 2 1 Pex19 protein family TraB PF01963.12 KFH44744.1 - 0.033 13.6 1.4 0.056 12.8 0.7 1.7 1 1 0 1 1 1 0 TraB family DUF236 PF03057.9 KFH44744.1 - 9.8 6.1 14.1 1.2 9.0 4.7 2.5 1 1 0 2 2 2 0 Protein of unknown function Peptidase_M48 PF01435.13 KFH44746.1 - 1.5e-37 129.3 0.0 1.9e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M48 Dickkopf_N PF04706.7 KFH44747.1 - 0.12 12.5 4.4 0.2 11.8 3.0 1.4 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Toxin_25 PF08095.6 KFH44747.1 - 0.13 12.0 2.3 0.43 10.3 1.6 2.0 1 1 0 1 1 1 0 Hefutoxin family Opy2 PF09463.5 KFH44747.1 - 0.32 11.1 2.8 0.25 11.4 0.8 1.8 2 0 0 2 2 2 0 Opy2 protein Asn_synthase PF00733.16 KFH44748.1 - 2.8e-68 230.1 0.0 3.9e-68 229.6 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KFH44748.1 - 6.7e-36 122.7 0.0 1.1e-35 122.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KFH44748.1 - 4.5e-28 97.8 0.0 1.5e-27 96.1 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KFH44748.1 - 1.5e-09 37.4 0.0 2.5e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 KFH44748.1 - 0.00041 19.3 0.0 0.001 18.0 0.0 1.6 1 1 0 1 1 1 1 NAD synthase GATase_2 PF00310.16 KFH44748.1 - 0.0049 15.6 0.0 0.53 8.9 0.0 2.7 1 1 2 3 3 3 1 Glutamine amidotransferases class-II PXA PF02194.10 KFH44751.1 - 1.1e-34 119.5 0.0 2.8e-34 118.3 0.0 1.7 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.7 KFH44751.1 - 5.6e-20 71.5 0.1 1.4e-19 70.2 0.0 1.7 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.19 KFH44751.1 - 3.5e-07 29.9 0.0 1.3e-06 28.1 0.0 2.0 1 0 0 1 1 1 1 PX domain Coatomer_E PF04733.9 KFH44753.1 - 1.7e-63 214.5 1.8 2e-63 214.3 1.2 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 KFH44753.1 - 1.4e-08 34.9 13.4 0.00023 21.4 0.7 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFH44753.1 - 9.6e-06 25.8 15.4 0.0013 19.2 0.6 6.0 5 3 1 7 7 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 KFH44753.1 - 9.7e-06 24.8 1.1 0.0078 15.3 0.1 2.5 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFH44753.1 - 3.9e-05 23.0 0.4 0.018 14.6 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFH44753.1 - 5.4e-05 22.6 0.0 0.02 14.6 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFH44753.1 - 7.3e-05 22.3 1.8 0.0027 17.3 0.0 3.8 3 1 0 4 4 4 1 TPR repeat Apc3 PF12895.2 KFH44753.1 - 7.6e-05 22.7 0.3 0.49 10.5 0.1 3.6 2 1 2 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 Type_III_YscG PF09477.5 KFH44753.1 - 0.00012 22.1 4.0 0.23 11.5 0.0 3.7 1 1 3 4 4 4 1 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_16 PF13432.1 KFH44753.1 - 0.00014 22.3 11.8 0.0015 19.1 0.3 4.6 4 2 0 4 4 4 1 Tetratricopeptide repeat TPR_5 PF12688.2 KFH44753.1 - 0.00015 21.7 2.2 0.15 12.0 0.0 2.6 2 1 0 2 2 2 2 Tetratrico peptide repeat TPR_6 PF13174.1 KFH44753.1 - 0.0002 21.6 1.9 0.14 12.6 0.0 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFH44753.1 - 0.00063 19.6 6.9 0.041 13.8 0.3 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFH44753.1 - 0.0022 17.7 0.3 0.0022 17.7 0.2 5.6 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_10 PF13374.1 KFH44753.1 - 0.0023 17.8 1.3 5.5 7.0 0.1 4.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFH44753.1 - 0.0047 17.0 0.3 13 6.2 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 KFH44753.1 - 0.0092 16.3 19.6 0.12 12.8 0.2 5.8 8 0 0 8 8 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFH44753.1 - 0.01 15.5 6.8 1.4 8.8 0.1 5.3 6 1 1 7 7 6 0 Tetratricopeptide repeat NARP1 PF12569.3 KFH44753.1 - 0.019 13.7 1.7 0.89 8.2 0.1 2.3 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 SNAP PF14938.1 KFH44753.1 - 0.023 13.8 2.2 0.34 10.0 0.1 2.4 1 1 1 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_20 PF14561.1 KFH44753.1 - 0.052 13.6 0.3 4.9 7.3 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Clathrin PF00637.15 KFH44753.1 - 0.08 12.5 0.1 0.82 9.2 0.1 2.2 2 0 0 2 2 2 0 Region in Clathrin and VPS TPR_9 PF13371.1 KFH44753.1 - 0.12 12.2 6.1 0.18 11.6 0.3 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat RE_HaeIII PF09556.5 KFH44753.1 - 0.12 11.2 0.0 0.47 9.2 0.0 1.7 1 1 1 2 2 2 0 HaeIII restriction endonuclease YlqD PF11068.3 KFH44754.1 - 1.3 9.0 4.9 3.9 7.5 3.4 1.8 1 1 0 1 1 1 0 YlqD protein MBF1 PF08523.5 KFH44755.1 - 3.7e-25 87.7 0.7 6.8e-25 86.8 0.5 1.4 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 KFH44755.1 - 9.9e-10 38.1 0.0 1.9e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 KFH44755.1 - 0.00093 19.1 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 KFH44755.1 - 0.0076 16.4 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.1 KFH44755.1 - 0.069 12.5 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Med1 PF10744.4 KFH44756.1 - 2.7e-28 98.8 0.0 1.1e-27 96.7 0.0 1.9 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 DUF952 PF06108.7 KFH44757.1 - 8.3e-21 73.6 0.0 1.2e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF952) TRP PF06011.7 KFH44758.1 - 1.2e-145 485.4 31.1 1.5e-145 485.1 21.6 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KFH44758.1 - 1.4e-38 132.1 1.1 2.5e-38 131.3 0.7 1.4 1 0 0 1 1 1 1 ML-like domain VirB3 PF05101.8 KFH44758.1 - 1.8 8.6 10.2 1.5 8.8 0.1 3.2 3 0 0 3 3 3 0 Type IV secretory pathway, VirB3-like protein SUR7 PF06687.7 KFH44759.1 - 2e-18 66.7 2.0 2e-18 66.7 1.4 1.8 1 1 1 2 2 2 1 SUR7/PalI family Claudin_2 PF13903.1 KFH44759.1 - 0.0007 19.3 3.4 0.0007 19.3 2.4 2.1 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction ABC2_membrane_4 PF12730.2 KFH44759.1 - 0.18 10.9 9.9 0.44 9.6 1.3 2.2 1 1 1 2 2 2 0 ABC-2 family transporter protein Adeno_E3_CR2 PF02439.10 KFH44759.1 - 0.29 10.7 0.0 0.29 10.7 0.0 3.5 3 1 0 3 3 3 0 Adenovirus E3 region protein CR2 DUF2723 PF11028.3 KFH44759.1 - 0.48 9.8 8.3 0.087 12.3 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2723) Orbi_NS3 PF01616.11 KFH44759.1 - 0.65 8.9 2.6 0.46 9.4 0.0 1.8 2 0 0 2 2 2 0 Orbivirus NS3 Claudin_3 PF06653.6 KFH44759.1 - 6.4 6.4 11.2 1.6 8.4 3.1 2.4 2 1 0 2 2 2 0 Tight junction protein, Claudin-like PC4 PF02229.11 KFH44760.1 - 2.4e-19 68.3 3.3 2e-14 52.5 0.7 2.3 2 0 0 2 2 2 2 Transcriptional Coactivator p15 (PC4) Stm1_N PF09598.5 KFH44760.1 - 0.0008 20.0 6.8 0.021 15.4 1.2 2.4 2 0 0 2 2 2 2 Stm1 DUF4611 PF15387.1 KFH44761.1 - 6.6 6.9 6.0 24 5.1 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) zf-CCHC PF00098.18 KFH44762.1 - 1.5 8.8 33.5 0.49 10.4 0.4 5.8 5 1 0 5 5 5 0 Zinc knuckle SUR7 PF06687.7 KFH44763.1 - 9.4e-32 110.2 13.4 1.3e-31 109.8 9.3 1.2 1 0 0 1 1 1 1 SUR7/PalI family Peptidase_M1 PF01433.15 KFH44766.1 - 1.7e-70 238.1 0.0 2.2e-70 237.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 KFH44766.1 - 1.1e-46 157.9 0.0 1.9e-46 157.2 0.0 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 KFH44766.1 - 1.4e-19 70.3 0.4 2.7e-19 69.4 0.3 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 KFH44766.1 - 0.49 10.3 4.3 0.94 9.4 1.7 2.4 2 1 0 2 2 2 0 M61 glycyl aminopeptidase Chorion_2 PF03964.10 KFH44767.1 - 0.36 11.3 3.4 0.66 10.5 2.4 1.4 1 0 0 1 1 1 0 Chorion family 2 DnaJ PF00226.26 KFH44768.1 - 6.9e-16 57.7 0.1 1.1e-15 57.0 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain SpoU_methylase PF00588.14 KFH44769.1 - 4.1e-26 91.5 0.0 6.4e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 KFH44769.1 - 4.1e-10 39.6 0.0 7.4e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Dynactin_p22 PF07426.6 KFH44769.1 - 0.15 11.3 0.5 0.24 10.6 0.3 1.3 1 0 0 1 1 1 0 Dynactin subunit p22 DUF3405 PF11885.3 KFH44770.1 - 7e-179 595.1 1.2 1e-178 594.6 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Uds1 PF15456.1 KFH44771.1 - 3.6e-24 85.1 6.5 5.8e-22 77.9 1.4 4.0 5 0 0 5 5 5 2 Up-regulated During Septation NAD_binding_5 PF07994.7 KFH44772.1 - 2.5e-114 381.7 0.4 3e-114 381.4 0.3 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 KFH44772.1 - 6.6e-46 154.7 0.7 1.4e-45 153.6 0.5 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase FNIP_C PF14638.1 KFH44772.1 - 0.038 13.3 0.0 0.12 11.7 0.0 1.8 1 0 0 1 1 1 0 Folliculin-interacting protein C-terminus FERM_N PF09379.5 KFH44773.1 - 0.097 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 FERM N-terminal domain Sec6 PF06046.8 KFH44774.1 - 3e-159 530.7 2.6 3.7e-159 530.4 1.8 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.7 KFH44774.1 - 0.013 14.3 0.5 0.013 14.3 0.4 2.5 2 2 2 4 4 4 0 Vps53-like, N-terminal OmdA PF13376.1 KFH44774.1 - 0.047 13.3 1.4 0.1 12.2 0.0 2.4 3 0 0 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated DENN PF02141.16 KFH44775.1 - 4.4e-41 140.6 0.1 7.8e-41 139.8 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 KFH44775.1 - 0.00044 20.1 0.0 0.0014 18.5 0.0 2.0 1 0 0 1 1 1 1 uDENN domain Elongin_A PF06881.6 KFH44775.1 - 0.0067 16.7 5.6 0.0067 16.7 3.9 2.2 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A PCRF PF03462.13 KFH44775.1 - 0.065 12.9 2.9 0.43 10.2 0.2 2.4 2 0 0 2 2 2 0 PCRF domain DUF2570 PF10828.3 KFH44775.1 - 0.72 9.4 13.8 0.4 10.2 7.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) CFEM PF05730.6 KFH44776.1 - 1.1e-12 47.5 4.7 2.2e-12 46.6 3.2 1.5 1 0 0 1 1 1 1 CFEM domain DNA_pol_viral_N PF00242.12 KFH44776.1 - 1.9 7.4 7.4 2.1 7.3 5.1 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Macoilin PF09726.4 KFH44776.1 - 2 6.6 15.9 2.3 6.3 11.0 1.0 1 0 0 1 1 1 0 Transmembrane protein DDHD PF02862.12 KFH44776.1 - 4 7.1 7.3 5.3 6.7 5.0 1.2 1 0 0 1 1 1 0 DDHD domain MCLC PF05934.6 KFH44776.1 - 8.4 4.5 9.7 11 4.2 6.7 1.3 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) DUF2264 PF10022.4 KFH44777.1 - 1.9e-117 391.9 0.2 2.5e-117 391.5 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) DUF600 PF04634.7 KFH44777.1 - 0.065 13.2 0.2 0.11 12.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF600 Peptidase_C36 PF05415.6 KFH44777.1 - 0.08 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Beet necrotic yellow vein furovirus-type papain-like endopeptidase Perilipin PF03036.11 KFH44778.1 - 0.00028 19.8 0.0 0.00031 19.7 0.0 1.1 1 0 0 1 1 1 1 Perilipin family Myosin_tail_1 PF01576.14 KFH44779.1 - 0.0014 16.5 10.1 0.0014 16.5 7.0 1.3 1 1 0 1 1 1 1 Myosin tail DUF1664 PF07889.7 KFH44779.1 - 0.53 10.0 8.4 0.14 11.9 0.6 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) AATF-Che1 PF13339.1 KFH44779.1 - 0.59 10.2 7.3 0.36 10.9 2.4 2.4 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor GrpE PF01025.14 KFH44779.1 - 0.69 9.4 10.1 0.32 10.5 4.9 1.9 1 1 1 2 2 2 0 GrpE V_ATPase_I PF01496.14 KFH44779.1 - 1.9 6.2 5.3 2.7 5.7 3.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Laminin_II PF06009.7 KFH44779.1 - 2.2 8.0 11.2 6.7 6.4 4.8 3.2 2 1 2 4 4 4 0 Laminin Domain II zf-C4H2 PF10146.4 KFH44779.1 - 3.4 7.6 12.6 0.72 9.8 5.5 2.1 1 1 1 2 2 2 0 Zinc finger-containing protein Mnd1 PF03962.10 KFH44779.1 - 4.1 7.0 10.7 1.6 8.3 5.1 2.0 1 1 1 2 2 2 0 Mnd1 family DUF4600 PF15372.1 KFH44779.1 - 6 7.0 12.0 0.67 10.1 3.8 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4600) APG6 PF04111.7 KFH44779.1 - 6.7 5.6 12.3 3.7 6.4 7.0 1.6 1 1 0 1 1 1 0 Autophagy protein Apg6 Fib_alpha PF08702.5 KFH44779.1 - 6.7 6.8 6.9 1.9 8.5 1.2 2.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Atg14 PF10186.4 KFH44779.1 - 7.1 5.4 7.1 4.4 6.1 0.1 2.3 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-Q PF13094.1 KFH44779.1 - 9.7 6.1 14.2 5.1 7.0 5.7 2.5 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit TPR_MLP1_2 PF07926.7 KFH44779.1 - 9.9 5.9 13.2 4.2 7.1 6.2 2.4 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Fungal_trans PF04082.13 KFH44780.1 - 9.4e-09 34.5 0.0 1.6e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH44780.1 - 5.9e-05 22.8 12.5 9.7e-05 22.1 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GATase PF00117.23 KFH44781.1 - 4.9e-12 45.6 0.0 6.4e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KFH44781.1 - 0.00011 21.7 2.1 0.0019 17.7 1.4 2.3 1 1 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.9 KFH44781.1 - 0.05 13.2 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain VirJ PF06057.6 KFH44781.1 - 0.12 12.1 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Het-C PF07217.6 KFH44782.1 - 3.4e-279 927.2 0.0 4.2e-279 926.8 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C BTB PF00651.26 KFH44783.1 - 0.067 13.1 0.0 20 5.1 0.0 2.6 2 0 0 2 2 2 0 BTB/POZ domain His_Phos_1 PF00300.17 KFH44784.1 - 6.6e-34 117.2 0.0 6.6e-34 117.2 0.0 2.1 3 0 0 3 3 3 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 KFH44784.1 - 1.9e-05 24.2 0.0 3.8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) BTV_NS2 PF04514.7 KFH44784.1 - 1.9 7.2 11.6 0.61 8.9 4.3 2.1 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 VWA_2 PF13519.1 KFH44785.1 - 3.6e-08 33.7 0.0 6.8e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KFH44785.1 - 4.8e-08 32.9 0.0 1.1e-07 31.7 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 KFH44785.1 - 0.0011 18.8 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus Decorin_bind PF02352.10 KFH44785.1 - 0.037 14.0 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 Decorin binding protein VWA_3 PF13768.1 KFH44785.1 - 0.068 12.8 0.0 0.21 11.2 0.0 1.8 1 1 0 1 1 1 0 von Willebrand factor type A domain DUF4013 PF13197.1 KFH44786.1 - 0.0001 21.7 0.9 0.00016 21.0 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4013) EamA PF00892.15 KFH44787.1 - 2.5e-18 66.3 23.7 5.2e-10 39.4 5.5 2.4 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 KFH44787.1 - 0.0011 19.2 25.8 0.0029 17.7 4.8 3.5 2 1 0 3 3 3 2 Multidrug resistance efflux transporter PIRT PF15099.1 KFH44787.1 - 0.15 11.2 4.5 0.96 8.6 0.7 2.6 3 0 0 3 3 3 0 Phosphoinositide-interacting protein family RRM_1 PF00076.17 KFH44788.1 - 8e-45 150.3 1.2 5.5e-21 73.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH44788.1 - 2.7e-35 120.1 0.2 3.5e-17 62.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 KFH44788.1 - 5.6e-28 97.0 0.1 1.2e-27 95.9 0.1 1.6 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 KFH44788.1 - 6.3e-22 77.1 0.0 3.1e-08 33.3 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFH44788.1 - 0.0028 17.3 0.0 1 9.2 0.0 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KFH44788.1 - 0.0032 17.2 0.2 0.085 12.7 0.0 2.7 2 1 0 2 2 2 1 RNA binding motif HMG_box PF00505.14 KFH44789.1 - 1.9e-18 66.4 0.3 3.7e-18 65.5 0.2 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFH44789.1 - 0.0053 17.0 0.3 0.011 16.1 0.2 1.5 1 0 0 1 1 1 1 HMG-box domain DUF1289 PF06945.8 KFH44789.1 - 0.029 13.8 1.8 0.16 11.4 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) Glyco_hydro_2_C PF02836.12 KFH44790.1 - 1.4e-92 309.8 0.0 1.9e-92 309.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 KFH44790.1 - 1e-56 192.0 0.0 1.8e-56 191.1 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 KFH44790.1 - 2.6e-56 189.7 6.3 4.2e-56 189.0 2.2 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KFH44790.1 - 4.4e-10 39.9 0.0 9.9e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_72 PF03198.9 KFH44790.1 - 1.3e-05 24.3 0.1 0.00037 19.5 0.0 2.4 3 0 0 3 3 3 1 Glucanosyltransferase HYLS1_C PF15311.1 KFH44790.1 - 3.9 7.7 5.6 85 3.4 0.1 4.0 4 0 0 4 4 4 0 Hydrolethalus syndrome protein 1 C-terminus Tcp11 PF05794.8 KFH44791.1 - 1.9e-82 277.3 0.0 7.4e-78 262.2 0.0 2.1 2 0 0 2 2 2 2 T-complex protein 11 TatD_DNase PF01026.16 KFH44792.1 - 9.2e-46 156.1 0.0 2.5e-45 154.6 0.0 1.6 1 1 0 1 1 1 1 TatD related DNase MSA-2c PF12238.3 KFH44792.1 - 0.054 13.1 1.7 1.2 8.8 0.5 2.1 2 0 0 2 2 2 0 Merozoite surface antigen 2c Ecl1 PF12855.2 KFH44793.1 - 1.4e-10 40.2 1.1 2.9e-10 39.2 0.8 1.5 1 0 0 1 1 1 1 Life-span regulatory factor DUF329 PF03884.9 KFH44793.1 - 0.11 12.0 0.9 0.27 10.8 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF329) zf-ribbon_3 PF13248.1 KFH44793.1 - 0.14 11.3 0.3 0.22 10.7 0.2 1.3 1 0 0 1 1 1 0 zinc-ribbon domain DUF2116 PF09889.4 KFH44793.1 - 2.2 8.1 6.2 0.25 11.1 0.3 2.1 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF1242 PF06842.7 KFH44794.1 - 1.5e-16 59.5 0.1 2.4e-16 58.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Aminotran_1_2 PF00155.16 KFH44795.1 - 3.6e-32 111.7 0.0 4.7e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1330 PF07045.6 KFH44796.1 - 5.8e-17 61.3 0.0 8.7e-17 60.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1330) YCII PF03795.9 KFH44796.1 - 0.063 13.4 0.0 0.12 12.6 0.0 1.7 1 1 0 1 1 1 0 YCII-related domain GMC_oxred_N PF00732.14 KFH44797.1 - 1.8e-40 138.9 0.3 3.2e-40 138.1 0.2 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFH44797.1 - 1.1e-27 97.0 1.4 7.6e-26 91.1 0.1 2.7 2 1 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 KFH44797.1 - 9.7e-06 24.7 2.7 0.0034 16.3 0.5 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFH44797.1 - 2.2e-05 23.5 4.2 4e-05 22.6 2.9 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KFH44797.1 - 5.5e-05 23.1 0.2 0.00032 20.6 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFH44797.1 - 0.00032 19.8 0.3 0.0008 18.5 0.2 1.6 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 KFH44797.1 - 0.00059 18.9 0.4 0.00087 18.4 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KFH44797.1 - 0.015 15.3 5.1 0.017 15.1 1.7 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KFH44797.1 - 0.057 11.8 1.4 0.09 11.2 1.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.2 KFH44797.1 - 0.086 11.8 4.1 0.13 11.3 2.9 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KFH44797.1 - 0.12 11.2 0.1 0.2 10.5 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 KFH44797.1 - 0.21 10.4 1.8 0.54 9.0 0.8 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A NMT1 PF09084.6 KFH44798.1 - 2.6e-76 255.9 0.0 3.2e-76 255.7 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 KFH44798.1 - 6.3e-09 35.5 0.1 0.015 14.6 0.0 3.1 3 0 0 3 3 3 3 NMT1-like family Phosphonate-bd PF12974.2 KFH44798.1 - 0.00073 18.9 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein PBP_like PF12727.2 KFH44798.1 - 0.093 11.6 0.0 1.7 7.5 0.0 2.1 2 0 0 2 2 2 0 PBP superfamily domain SRP19 PF01922.12 KFH44799.1 - 2.9e-28 98.3 0.0 6.1e-28 97.2 0.0 1.6 1 0 0 1 1 1 1 SRP19 protein AAA PF00004.24 KFH44801.1 - 7.7e-37 126.4 0.0 6.3e-12 45.8 0.0 4.2 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFH44801.1 - 6.8e-13 48.9 10.5 0.0017 18.4 0.7 6.8 4 3 0 4 4 4 3 AAA domain AAA_19 PF13245.1 KFH44801.1 - 1.4e-11 43.9 0.4 0.015 15.0 0.0 3.7 3 0 0 3 3 3 3 Part of AAA domain AAA_5 PF07728.9 KFH44801.1 - 2.2e-10 40.4 0.4 0.02 14.6 0.0 4.0 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KFH44801.1 - 1.8e-09 38.4 7.3 0.034 14.9 0.0 4.6 4 1 0 4 4 4 3 AAA domain AAA_16 PF13191.1 KFH44801.1 - 2.4e-09 37.4 6.1 0.021 14.7 0.0 4.8 4 1 0 4 4 4 3 AAA ATPase domain AAA_11 PF13086.1 KFH44801.1 - 3.8e-07 29.9 0.2 0.014 15.0 0.0 4.0 3 1 0 3 3 3 1 AAA domain Mg_chelatase PF01078.16 KFH44801.1 - 3.9e-07 29.4 0.1 0.2 10.7 0.0 3.6 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 KFH44801.1 - 4.6e-07 29.1 0.0 0.083 11.9 0.0 3.7 4 0 0 4 4 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KFH44801.1 - 5.9e-07 29.4 0.8 0.45 10.3 0.0 4.0 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.1 KFH44801.1 - 7.6e-07 28.9 1.4 1.2 8.7 0.0 5.0 4 2 0 4 4 4 3 AAA domain RNA_helicase PF00910.17 KFH44801.1 - 1.9e-06 27.9 0.0 0.6 10.3 0.0 3.7 3 0 0 3 3 3 2 RNA helicase IstB_IS21 PF01695.12 KFH44801.1 - 1.4e-05 24.5 0.0 0.54 9.6 0.0 3.6 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_18 PF13238.1 KFH44801.1 - 7.5e-05 23.0 9.1 0.99 9.7 0.0 4.4 4 0 0 4 4 3 3 AAA domain AAA_25 PF13481.1 KFH44801.1 - 0.00018 20.9 0.7 4.2 6.7 0.0 4.7 3 1 0 4 4 4 1 AAA domain AAA_24 PF13479.1 KFH44801.1 - 0.00018 21.1 7.6 0.96 8.9 0.2 4.0 2 1 1 3 3 3 2 AAA domain Sigma54_activat PF00158.21 KFH44801.1 - 0.00031 20.2 0.5 9.3 5.6 0.0 4.4 4 1 0 4 4 4 0 Sigma-54 interaction domain Torsin PF06309.6 KFH44801.1 - 0.00043 20.1 0.0 3.1 7.6 0.0 3.8 3 0 0 3 3 3 1 Torsin Viral_helicase1 PF01443.13 KFH44801.1 - 0.001 18.6 0.9 0.24 10.8 0.0 3.4 3 1 0 3 3 3 1 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 KFH44801.1 - 0.0013 18.4 1.5 6.8 6.3 0.0 3.9 3 0 0 3 3 3 0 NTPase AAA_29 PF13555.1 KFH44801.1 - 0.0032 16.9 0.3 3.7 7.1 0.0 3.4 3 0 0 3 3 3 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KFH44801.1 - 0.0032 17.7 2.1 11 6.3 0.0 3.8 3 0 0 3 3 3 0 ABC transporter ADK PF00406.17 KFH44801.1 - 0.0046 16.8 2.0 9.5 6.0 0.1 4.1 4 0 0 4 4 3 0 Adenylate kinase Zeta_toxin PF06414.7 KFH44801.1 - 0.0064 15.6 0.1 7.9 5.5 0.0 3.4 3 0 0 3 3 3 0 Zeta toxin MobB PF03205.9 KFH44801.1 - 0.0085 15.8 1.0 5.3 6.7 0.0 3.4 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 KFH44801.1 - 0.015 14.2 0.0 9.6 4.9 0.0 3.5 3 0 0 3 3 3 0 NB-ARC domain SRP54 PF00448.17 KFH44801.1 - 0.023 14.1 1.4 1.4 8.3 0.0 3.5 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain ArgK PF03308.11 KFH44801.1 - 0.025 13.3 8.9 0.95 8.1 0.0 4.1 4 0 0 4 4 4 0 ArgK protein AAA_10 PF12846.2 KFH44801.1 - 0.082 12.3 12.7 3.9 6.8 0.2 5.7 4 2 2 6 6 6 0 AAA-like domain DUF2075 PF09848.4 KFH44801.1 - 0.27 10.1 6.3 29 3.5 0.4 4.5 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 KFH44801.1 - 0.36 9.8 2.3 20 4.2 0.0 3.3 3 0 0 3 3 3 0 KaiC AAA_28 PF13521.1 KFH44801.1 - 0.58 10.1 13.9 8.5 6.3 0.0 4.3 4 1 0 4 4 3 0 AAA domain KTI12 PF08433.5 KFH44801.1 - 2.3 7.3 10.6 18 4.4 0.0 4.4 4 1 1 5 5 5 0 Chromatin associated protein KTI12 bZIP_2 PF07716.10 KFH44803.1 - 1.7e-12 46.9 10.2 1.7e-12 46.9 7.1 1.6 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 KFH44803.1 - 0.00026 20.8 13.4 0.001 19.0 9.3 1.9 1 1 0 1 1 1 1 bZIP transcription factor IncA PF04156.9 KFH44803.1 - 0.02 14.5 5.3 0.028 14.0 3.7 1.2 1 0 0 1 1 1 0 IncA protein PRESAN PF09687.5 KFH44803.1 - 0.027 14.5 0.1 0.047 13.7 0.1 1.3 1 0 0 1 1 1 0 Plasmodium RESA N-terminal TSC22 PF01166.13 KFH44803.1 - 0.032 14.1 0.3 0.069 13.1 0.2 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family Shugoshin_N PF07558.6 KFH44803.1 - 0.063 12.9 0.7 0.13 11.9 0.5 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Lzipper-MIP1 PF14389.1 KFH44803.1 - 0.076 13.1 1.5 2.8 8.1 1.1 2.2 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 XhlA PF10779.4 KFH44803.1 - 0.3 11.0 2.4 0.54 10.2 1.6 1.4 1 0 0 1 1 1 0 Haemolysin XhlA HSP70 PF00012.15 KFH44803.1 - 1.6 6.5 6.7 2.1 6.1 4.7 1.1 1 0 0 1 1 1 0 Hsp70 protein Seryl_tRNA_N PF02403.17 KFH44803.1 - 1.9 8.5 7.4 1.8 8.6 4.3 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain V_ATPase_I PF01496.14 KFH44803.1 - 3.4 5.4 4.9 4.1 5.1 3.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Macoilin PF09726.4 KFH44803.1 - 3.5 5.7 11.2 4.3 5.5 7.8 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF972 PF06156.8 KFH44803.1 - 5.8 7.3 7.1 4.1 7.8 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) OMPdecase PF00215.19 KFH44804.1 - 3.6e-104 347.0 0.0 4.3e-104 346.8 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family zf-CCCH PF00642.19 KFH44805.1 - 0.0019 17.8 2.9 0.0019 17.8 2.0 2.1 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1917 PF08939.5 KFH44805.1 - 0.032 13.9 0.1 0.47 10.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1917) Mod_r PF07200.8 KFH44805.1 - 0.046 13.6 2.8 0.091 12.6 1.9 1.5 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein ACDC PF14733.1 KFH44805.1 - 0.075 13.1 0.3 0.15 12.2 0.2 1.4 1 0 0 1 1 1 0 AP2-coincident C-terminal Med3 PF11593.3 KFH44805.1 - 0.93 8.6 16.9 1.3 8.1 11.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TFIIA PF03153.8 KFH44805.1 - 1.1 9.0 4.6 1.8 8.3 3.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Apc15p PF05841.6 KFH44805.1 - 1.3 9.8 5.2 2.6 8.8 3.2 1.9 2 0 0 2 2 2 0 Apc15p protein Pirin PF02678.11 KFH44806.1 - 3e-32 110.6 2.7 1.3e-31 108.5 0.0 2.8 3 0 0 3 3 3 1 Pirin Pirin_C PF05726.8 KFH44806.1 - 5.4e-25 87.4 0.0 1.9e-23 82.4 0.0 2.3 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 KFH44806.1 - 6.4e-06 25.5 2.7 9e-05 21.8 0.3 3.5 3 0 0 3 3 3 2 Cupin domain Zip PF02535.17 KFH44806.1 - 0.036 13.0 2.4 0.051 12.5 1.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 KFH44806.1 - 0.068 12.5 8.1 0.1 11.9 5.6 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Cupin_3 PF05899.7 KFH44806.1 - 0.079 12.3 0.9 4.3 6.8 0.0 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF861) DUF2547 PF10818.3 KFH44806.1 - 0.13 12.8 4.5 0.28 11.8 3.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2547) PP2C PF00481.16 KFH44807.1 - 6.5e-38 130.5 0.0 6.8e-32 110.8 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 KFH44807.1 - 7.5e-06 25.4 0.0 1.9e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C CDP-OH_P_transf PF01066.16 KFH44808.1 - 1.1e-16 60.9 5.7 1.1e-16 60.9 3.9 1.8 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase ESR1_C PF12743.2 KFH44808.1 - 4.3 6.9 6.8 0.63 9.6 0.9 2.3 2 0 0 2 2 2 0 Oestrogen-type nuclear receptor final C-terminal Response_reg PF00072.19 KFH44809.1 - 4.2e-22 78.2 0.2 1.1e-21 76.9 0.0 1.8 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 KFH44809.1 - 1.4e-21 76.2 0.2 3.7e-21 74.9 0.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KFH44809.1 - 5.9e-21 74.2 1.5 1e-20 73.4 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 KFH44809.1 - 4.2e-20 71.6 0.9 1e-10 41.5 0.2 3.6 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.1 KFH44809.1 - 1.2e-14 54.5 0.0 1.6e-07 31.6 0.0 3.4 2 1 0 2 2 2 2 PAS domain PAS_4 PF08448.5 KFH44809.1 - 5.5e-07 29.6 0.0 2.4e-05 24.3 0.0 3.0 2 0 0 2 2 2 1 PAS fold PAS PF00989.19 KFH44809.1 - 2.7e-05 23.9 0.0 0.25 11.1 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.1 KFH44809.1 - 0.073 12.9 0.0 2 8.4 0.0 2.6 2 0 0 2 2 2 0 PAS domain FA_hydroxylase PF04116.8 KFH44810.1 - 1.5e-15 57.5 11.7 1.5e-15 57.5 8.1 2.3 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily DUF1168 PF06658.7 KFH44811.1 - 1.8e-42 144.2 13.7 2.4e-42 143.7 9.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Transformer PF06495.6 KFH44811.1 - 0.0059 16.5 6.4 0.011 15.6 4.4 1.5 1 0 0 1 1 1 1 Fruit fly transformer protein RNA_polI_A34 PF08208.6 KFH44811.1 - 0.16 11.6 11.9 0.2 11.3 7.9 1.4 1 1 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 eIF-3_zeta PF05091.7 KFH44811.1 - 0.26 9.8 2.7 0.28 9.7 1.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Hex_IIIa PF02455.11 KFH44811.1 - 0.57 8.7 3.0 0.7 8.5 2.1 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) U79_P34 PF03064.11 KFH44811.1 - 1.5 8.3 14.0 2.2 7.7 9.7 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 ATP11 PF06644.6 KFH44811.1 - 2.1 7.7 4.7 3 7.2 3.3 1.2 1 0 0 1 1 1 0 ATP11 protein RNase_H2-Ydr279 PF09468.5 KFH44811.1 - 4.7 6.3 5.6 6.7 5.8 3.9 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) D-ser_dehydrat PF14031.1 KFH44812.1 - 0.00015 21.8 1.1 0.00022 21.3 0.0 1.7 2 0 0 2 2 2 1 Putative serine dehydratase domain Cyt-b5 PF00173.23 KFH44813.1 - 3.5e-21 74.7 0.3 1.4e-20 72.8 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 KFH44813.1 - 5.9e-07 29.8 22.5 5.9e-07 29.8 15.6 1.8 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily COX14 PF14880.1 KFH44813.1 - 0.17 11.4 3.5 0.85 9.2 0.3 2.5 2 0 0 2 2 2 0 Cytochrome oxidase c assembly EF-hand_4 PF12763.2 KFH44814.1 - 3.6e-17 61.9 0.0 4.3e-06 26.4 0.0 3.5 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand UBA PF00627.26 KFH44814.1 - 1.6e-05 24.5 0.0 4.3e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain DUF4239 PF14023.1 KFH44814.1 - 3 7.1 3.5 3.8 6.7 1.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) Reo_sigmaC PF04582.7 KFH44814.1 - 3.2 6.8 8.0 0.33 10.0 0.6 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein zf-C4H2 PF10146.4 KFH44814.1 - 4 7.4 21.6 0.03 14.3 7.5 3.0 2 1 0 2 2 2 0 Zinc finger-containing protein TFIID-18kDa PF02269.11 KFH44815.1 - 2.1e-18 65.8 0.1 3.3e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 KFH44815.1 - 0.0039 16.8 0.0 0.0064 16.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.19 KFH44815.1 - 0.0079 16.3 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFH44815.1 - 0.1 12.6 0.5 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TIP49 PF06068.8 KFH44816.1 - 4.8e-187 621.5 0.1 5.6e-187 621.3 0.1 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 KFH44816.1 - 2.8e-10 40.4 0.2 1.6e-06 28.3 0.1 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KFH44816.1 - 2.1e-09 36.7 0.3 1.8e-06 27.2 0.0 3.1 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KFH44816.1 - 1.5e-05 24.6 0.3 7.3e-05 22.4 0.1 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 KFH44816.1 - 0.0001 22.4 0.2 0.51 10.4 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 KFH44816.1 - 0.0003 20.8 0.0 0.071 13.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.1 KFH44816.1 - 0.0013 18.7 0.1 0.0027 17.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KFH44816.1 - 0.0032 16.9 0.0 0.015 14.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KFH44816.1 - 0.0047 16.0 0.2 0.014 14.5 0.1 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_5 PF07728.9 KFH44816.1 - 0.0057 16.3 0.2 0.12 12.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KFH44816.1 - 0.01 15.2 0.1 0.023 14.1 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.4 KFH44816.1 - 0.025 13.5 0.1 0.082 11.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.21 KFH44816.1 - 0.027 13.9 0.0 1.4 8.3 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.1 KFH44816.1 - 0.027 14.7 0.1 0.074 13.3 0.1 1.9 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KFH44816.1 - 0.033 13.3 0.1 0.67 9.0 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DnaB_C PF03796.10 KFH44816.1 - 0.034 13.0 0.0 0.063 12.1 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_33 PF13671.1 KFH44816.1 - 0.067 13.0 0.0 0.91 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KFH44816.1 - 0.079 13.7 0.1 0.19 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain MinE PF03776.9 KFH44816.1 - 0.081 12.4 0.1 0.2 11.1 0.1 1.6 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE Uds1 PF15456.1 KFH44817.1 - 4.9e-44 149.2 4.0 4.9e-44 149.2 2.8 6.5 4 1 3 7 7 7 2 Up-regulated During Septation Reo_sigmaC PF04582.7 KFH44817.1 - 0.069 12.3 9.6 0.15 11.2 0.9 3.4 2 1 1 3 3 3 0 Reovirus sigma C capsid protein WEMBL PF05701.6 KFH44817.1 - 1.9 6.8 69.5 0.15 10.4 40.0 4.2 3 1 0 3 3 3 0 Weak chloroplast movement under blue light Cpn60_TCP1 PF00118.19 KFH44818.1 - 7.6e-162 539.2 0.4 8.6e-162 539.1 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SDA1 PF05285.7 KFH44820.1 - 0.00067 19.0 1.1 0.00083 18.7 0.8 1.0 1 0 0 1 1 1 1 SDA1 BAF1_ABF1 PF04684.8 KFH44820.1 - 0.018 13.8 5.0 0.015 14.1 3.4 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor FimP PF09766.4 KFH44820.1 - 0.023 13.7 4.9 0.032 13.3 3.4 1.2 1 0 0 1 1 1 0 Fms-interacting protein CENP-B_dimeris PF09026.5 KFH44820.1 - 0.055 13.7 0.9 0.11 12.7 0.3 1.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain FAM176 PF14851.1 KFH44820.1 - 0.15 11.7 1.2 0.25 11.0 0.9 1.3 1 0 0 1 1 1 0 FAM176 family TMEM51 PF15345.1 KFH44820.1 - 0.22 11.2 3.5 0.26 10.9 2.4 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Suf PF05843.9 KFH44820.1 - 0.32 10.6 3.0 0.37 10.4 2.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TraH PF06122.6 KFH44820.1 - 0.47 9.2 4.2 0.61 8.8 2.9 1.1 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein DUF788 PF05620.6 KFH44820.1 - 0.5 10.2 4.3 0.81 9.5 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF788) Borrelia_P83 PF05262.6 KFH44820.1 - 0.68 8.1 5.4 0.75 8.0 3.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4660 PF15559.1 KFH44820.1 - 5.4 7.1 8.1 8.8 6.4 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4660) Pyr_redox_2 PF07992.9 KFH44822.1 - 2.7e-39 135.1 0.0 6e-39 134.0 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KFH44822.1 - 2.5e-34 117.5 1.1 1.6e-33 115.0 0.3 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KFH44822.1 - 9.8e-20 70.7 3.1 1.8e-18 66.7 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFH44822.1 - 3.1e-11 43.7 0.6 4e-08 33.5 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFH44822.1 - 3.4e-07 29.5 0.0 0.00078 18.4 0.0 2.2 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 KFH44822.1 - 0.0002 19.9 1.1 0.053 11.9 0.0 3.0 3 0 0 3 3 3 1 HI0933-like protein AlaDh_PNT_C PF01262.16 KFH44822.1 - 0.00032 20.3 0.2 0.48 9.9 0.0 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 KFH44822.1 - 0.0007 18.5 0.1 0.008 15.0 0.1 2.4 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 KFH44822.1 - 0.0027 16.8 0.2 0.013 14.6 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KFH44822.1 - 0.043 12.9 0.0 0.089 11.8 0.0 1.6 1 0 0 1 1 1 0 Thi4 family DUF2673 PF10880.3 KFH44822.1 - 0.043 13.8 0.4 4 7.5 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2673) Toxin_62 PF15540.1 KFH44822.1 - 0.12 12.5 0.6 0.36 10.9 0.0 2.1 3 0 0 3 3 3 0 Putative toxin 62 3HCDH_N PF02737.13 KFH44822.1 - 0.15 11.6 0.0 0.15 11.6 0.0 2.4 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KFH44822.1 - 0.16 11.1 1.5 0.84 8.7 0.0 2.7 4 0 0 4 4 4 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ribonuc_red_lgC PF02867.10 KFH44823.1 - 1e-223 743.7 0.0 1.4e-223 743.3 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 KFH44823.1 - 5.4e-25 87.0 0.0 1.4e-24 85.6 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 KFH44823.1 - 2.1e-16 60.1 0.1 9.8e-16 57.9 0.0 2.3 2 0 0 2 2 2 1 ATP cone domain CENP-N PF05238.8 KFH44825.1 - 3.8e-114 381.8 0.0 4.9e-114 381.4 0.0 1.1 1 0 0 1 1 1 1 Kinetochore protein CHL4 like WD40 PF00400.27 KFH44826.1 - 4.8e-40 134.0 19.3 2.5e-09 36.6 0.0 10.5 11 0 0 11 11 11 6 WD domain, G-beta repeat NACHT PF05729.7 KFH44826.1 - 3e-14 53.0 0.0 5.7e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.7 KFH44826.1 - 1.2e-07 31.1 10.9 13 5.5 0.1 10.9 12 0 0 12 12 12 1 WD40-like Beta Propeller Repeat AAA_16 PF13191.1 KFH44826.1 - 0.0017 18.3 0.1 0.0052 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Apc4_WD40 PF12894.2 KFH44826.1 - 0.0086 15.5 0.0 8.2 6.0 0.0 4.6 6 0 0 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain AAA_19 PF13245.1 KFH44826.1 - 0.095 12.4 0.0 0.57 9.9 0.0 2.4 1 0 0 1 1 1 0 Part of AAA domain Arch_ATPase PF01637.13 KFH44826.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_22 PF13401.1 KFH44826.1 - 0.15 12.2 0.0 0.44 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 KFH44826.1 - 0.39 9.5 0.0 0.7 8.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain zf-HIT PF04438.11 KFH44827.1 - 2e-08 33.7 10.8 3e-08 33.1 7.5 1.3 1 0 0 1 1 1 1 HIT zinc finger ZZ PF00569.12 KFH44828.1 - 1.4e-10 40.5 7.7 2.5e-10 39.7 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.27 KFH44828.1 - 1e-08 33.8 19.3 0.0001 21.3 0.1 4.6 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.1 KFH44828.1 - 2.2e-07 30.8 8.2 0.0045 17.0 0.2 4.6 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.1 KFH44828.1 - 6e-07 28.8 14.7 0.00034 20.2 0.1 4.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 KFH44828.1 - 3.9e-05 23.1 3.4 0.13 11.9 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 KFH44828.1 - 0.0015 17.7 17.1 0.16 11.3 0.0 4.9 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.2 KFH44828.1 - 0.12 12.1 0.0 0.54 10.0 0.0 2.1 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand C1_3 PF07649.7 KFH44828.1 - 9.3 6.3 13.5 1 9.4 6.4 1.7 2 0 0 2 2 2 0 C1-like domain MFS_1 PF07690.11 KFH44829.1 - 1.5e-30 106.1 21.3 1.5e-30 106.1 14.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH44829.1 - 5.1e-10 38.5 13.3 3.8e-05 22.4 0.1 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 KFH44829.1 - 1.8e-06 26.6 3.0 1.8e-06 26.6 2.1 2.2 2 1 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.2 KFH44829.1 - 6.4e-05 22.6 1.1 0.36 10.6 0.0 2.9 3 0 0 3 3 3 2 MFS_1 like family Nop14 PF04147.7 KFH44831.1 - 0.043 11.7 16.6 0.056 11.3 11.5 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1656 PF07869.7 KFH44831.1 - 0.21 11.3 1.2 0.44 10.3 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) CENP-T PF15511.1 KFH44831.1 - 0.45 9.6 9.0 0.65 9.1 6.3 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Pkinase PF00069.20 KFH44832.1 - 2e-17 63.2 0.1 2.7e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH44832.1 - 9.3e-08 31.4 0.0 1.2e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFH44832.1 - 1.5e-05 24.8 0.1 3.1e-05 23.8 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KFH44832.1 - 2.5e-05 23.4 0.0 3.7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFH44832.1 - 0.00027 20.3 0.0 0.00043 19.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 KFH44832.1 - 0.00065 18.7 0.0 0.00081 18.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 KFH44832.1 - 0.00084 18.9 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Translin PF01997.11 KFH44834.1 - 7.2e-48 162.8 0.0 8.7e-48 162.5 0.0 1.1 1 0 0 1 1 1 1 Translin family Hemerythrin PF01814.18 KFH44834.1 - 0.0051 16.9 0.6 0.01 15.9 0.2 1.6 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain Baculo_p24 PF05073.7 KFH44834.1 - 0.15 11.5 0.1 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Baculovirus P24 capsid protein Glyco_hyd_65N_2 PF14498.1 KFH44835.1 - 8.5e-59 199.0 0.0 1.3e-58 198.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain adh_short_C2 PF13561.1 KFH44836.1 - 5.7e-25 88.4 0.0 7e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFH44836.1 - 4.7e-24 85.1 5.6 1.1e-23 83.9 3.9 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH44836.1 - 7.8e-11 41.9 1.3 7.8e-11 41.9 0.9 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KFH44836.1 - 1.1e-05 24.9 0.2 0.00019 20.9 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFH44836.1 - 0.00021 21.3 1.7 0.00053 20.0 1.1 1.6 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KFH44836.1 - 0.02 13.7 0.1 0.039 12.8 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KFH44836.1 - 0.073 11.7 0.1 0.12 11.0 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Abhydrolase_6 PF12697.2 KFH44837.1 - 1.2e-26 94.0 0.1 1.5e-26 93.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFH44837.1 - 2.7e-14 53.2 0.0 1.1e-12 48.0 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFH44837.1 - 1.5e-11 44.1 0.0 3e-11 43.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KFH44837.1 - 0.0043 16.9 0.0 0.0083 15.9 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.16 KFH44837.1 - 0.0047 16.1 0.1 2.8 7.1 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 KFH44837.1 - 0.0076 16.0 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 KFH44837.1 - 0.027 14.7 0.0 0.046 13.9 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF2048 PF09752.4 KFH44837.1 - 0.029 13.2 0.1 0.047 12.5 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) DUF1100 PF06500.6 KFH44837.1 - 0.047 12.2 0.0 0.067 11.7 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Esterase_phd PF10503.4 KFH44837.1 - 0.078 12.2 0.1 2.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase FMN_red PF03358.10 KFH44838.1 - 2e-24 85.8 0.0 2.8e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Rad1 PF02144.11 KFH44839.1 - 4.6e-81 271.6 0.0 5.4e-81 271.3 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Abhydrolase_6 PF12697.2 KFH44840.1 - 2e-14 54.0 0.4 3.2e-14 53.3 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH44840.1 - 8.2e-14 51.5 0.1 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFH44840.1 - 9e-10 38.4 0.0 1.8e-09 37.4 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KFH44840.1 - 1.1e-06 28.3 0.1 1.8e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 KFH44840.1 - 0.00062 19.2 0.0 0.00076 18.9 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 KFH44840.1 - 0.0016 18.2 0.2 0.0061 16.3 0.1 1.9 1 1 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 KFH44840.1 - 0.0021 17.2 0.1 0.024 13.8 0.1 2.2 2 1 0 2 2 2 1 Prolyl oligopeptidase family Cutinase PF01083.17 KFH44840.1 - 0.0033 17.1 0.0 0.005 16.5 0.0 1.2 1 0 0 1 1 1 1 Cutinase PQ-loop PF04193.9 KFH44841.1 - 6.2e-24 83.3 4.2 1.2e-14 53.5 0.4 2.7 2 0 0 2 2 2 2 PQ loop repeat FHA PF00498.21 KFH44844.1 - 1.5e-10 41.0 0.1 2.9e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 FHA domain BRCT PF00533.21 KFH44844.1 - 0.00035 20.6 0.1 0.0048 17.0 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Beta_elim_lyase PF01212.16 KFH44845.1 - 1.2e-42 146.0 0.0 1.5e-42 145.7 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KFH44845.1 - 0.00016 20.7 0.0 0.00023 20.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.16 KFH44845.1 - 0.00062 18.7 0.1 0.32 9.8 0.0 2.4 2 1 0 2 2 2 2 Aminotransferase class-III Capsid_NCLDV PF04451.7 KFH44846.1 - 0.2 10.6 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Large eukaryotic DNA virus major capsid protein DNA_pol_B PF00136.16 KFH44847.1 - 0.00018 20.4 0.1 0.00019 20.3 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase family B Nucleoplasmin PF03066.10 KFH44847.1 - 0.00062 19.3 3.7 0.00064 19.2 2.6 1.1 1 0 0 1 1 1 1 Nucleoplasmin DUF4611 PF15387.1 KFH44847.1 - 0.01 15.9 5.3 0.012 15.6 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Voldacs PF03517.8 KFH44847.1 - 0.02 14.7 0.5 0.02 14.7 0.3 1.1 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling RXT2_N PF08595.6 KFH44847.1 - 0.064 13.0 3.9 0.071 12.9 2.7 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal Sigma70_ner PF04546.8 KFH44847.1 - 0.068 12.7 5.2 0.072 12.6 3.6 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DNA_pol_B_2 PF03175.8 KFH44847.1 - 0.074 11.7 0.0 0.078 11.6 0.0 1.0 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral PBP1_TM PF14812.1 KFH44847.1 - 0.1 12.8 13.4 0.13 12.5 9.3 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TFIIF_alpha PF05793.7 KFH44847.1 - 0.32 9.3 7.6 0.35 9.1 5.2 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FAM176 PF14851.1 KFH44847.1 - 0.45 10.1 1.6 0.47 10.1 1.1 1.1 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.9 KFH44847.1 - 0.51 8.2 3.7 0.56 8.1 2.6 1.0 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 KFH44847.1 - 0.56 9.4 6.3 0.55 9.4 4.4 1.0 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 KFH44847.1 - 3.5 5.4 6.8 3.8 5.3 4.7 1.0 1 0 0 1 1 1 0 Nop14-like family Dicty_REP PF05086.7 KFH44847.1 - 3.8 5.1 4.9 3.9 5.1 3.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Cwf_Cwc_15 PF04889.7 KFH44847.1 - 4.6 6.8 10.6 5.2 6.7 7.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Tom22 PF04281.8 KFH44847.1 - 5 6.6 5.9 5.9 6.4 4.1 1.1 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 DUF2457 PF10446.4 KFH44847.1 - 5.4 5.6 18.2 6.6 5.3 12.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TLD PF07534.11 KFH44848.1 - 2.8e-30 105.1 0.0 5.5e-30 104.1 0.0 1.5 1 1 0 1 1 1 1 TLD MUG2_C PF08593.5 KFH44848.1 - 0.0033 17.6 3.1 0.023 14.9 2.1 2.5 1 1 0 1 1 1 1 Meiotically up-regulated glycoproteins C-terminal BSP_II PF05432.6 KFH44848.1 - 1.3 8.2 6.7 2.2 7.4 4.7 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Abhydrolase_2 PF02230.11 KFH44849.1 - 1.2e-05 24.8 0.0 1.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KFH44849.1 - 0.00018 21.2 0.1 0.00041 20.1 0.1 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFH44849.1 - 0.00021 20.5 0.2 0.00038 19.7 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 KFH44849.1 - 0.0045 16.2 1.2 0.0066 15.7 0.2 1.7 2 0 0 2 2 2 1 Esterase PHB depolymerase AXE1 PF05448.7 KFH44849.1 - 0.064 11.7 0.1 0.089 11.2 0.1 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.2 KFH44849.1 - 0.075 12.8 2.2 0.067 13.0 0.3 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family MFS_1 PF07690.11 KFH44850.1 - 4e-25 88.2 60.8 1.5e-16 60.1 20.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFH44850.1 - 4.9e-08 31.7 29.8 2.1e-07 29.7 10.5 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein ADH_N PF08240.7 KFH44851.1 - 6.3e-08 32.3 0.1 1.1e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KFH44851.1 - 4e-05 24.5 0.0 9.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Zn_clus PF00172.13 KFH44852.1 - 6.6e-09 35.5 10.7 1.1e-08 34.8 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFH44852.1 - 1.7e-06 26.9 1.5 1.7e-06 26.9 1.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Peptidase_S8 PF00082.17 KFH44853.1 - 2.9e-48 164.4 5.9 4.5e-48 163.8 4.1 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KFH44853.1 - 0.03 14.8 0.3 0.07 13.6 0.2 1.7 1 0 0 1 1 1 0 Peptidase inhibitor I9 DASH_Spc34 PF08657.5 KFH44854.1 - 0.0044 16.7 2.9 0.006 16.2 2.0 1.3 1 1 0 1 1 1 1 DASH complex subunit Spc34 IncA PF04156.9 KFH44854.1 - 0.0095 15.5 1.9 0.013 15.0 1.3 1.3 1 0 0 1 1 1 1 IncA protein Mod_r PF07200.8 KFH44854.1 - 0.014 15.3 1.5 0.022 14.6 1.0 1.4 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein YPEB PF14620.1 KFH44854.1 - 0.044 12.7 0.4 0.052 12.5 0.3 1.1 1 0 0 1 1 1 0 YpeB sporulation SPX PF03105.14 KFH44854.1 - 0.17 11.6 0.6 0.23 11.2 0.4 1.1 1 0 0 1 1 1 0 SPX domain TBPIP PF07106.8 KFH44854.1 - 0.25 10.8 3.7 1 8.8 1.3 2.4 1 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Pkinase PF00069.20 KFH44855.1 - 5.2e-36 124.1 0.0 1e-35 123.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH44855.1 - 1.4e-22 80.0 0.0 2e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH44855.1 - 0.024 13.5 0.0 0.04 12.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KFH44855.1 - 0.093 12.4 0.1 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family LSM PF01423.17 KFH44858.1 - 1e-16 60.2 0.1 1.3e-16 59.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain Rad4 PF03835.10 KFH44860.1 - 2.3e-15 56.2 3.3 4e-15 55.4 2.3 1.3 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 KFH44860.1 - 3.5e-10 40.0 3.1 7.9e-10 38.9 2.1 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Peptidase_M28 PF04389.12 KFH44861.1 - 1e-37 129.6 0.1 1.5e-37 129.0 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KFH44861.1 - 8.4e-16 57.5 0.0 2.2e-15 56.1 0.0 1.8 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 KFH44861.1 - 8.8e-08 31.8 0.0 1.6e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 KFH44861.1 - 0.033 12.9 0.0 0.054 12.2 0.0 1.3 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase MFS_1 PF07690.11 KFH44862.1 - 2.2e-34 118.7 24.5 2.4e-33 115.3 18.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH44862.1 - 0.0002 20.0 27.1 0.0028 16.3 18.6 2.6 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KFH44863.1 - 6.7e-44 150.0 57.4 5.8e-43 146.9 24.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KFH44863.1 - 0.017 14.8 1.2 0.12 12.2 0.0 2.9 3 0 0 3 3 3 0 MFS_1 like family DUF2235 PF09994.4 KFH44864.1 - 3.6e-57 193.8 0.0 6e-57 193.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DTW PF03942.10 KFH44864.1 - 0.0029 16.8 0.0 0.0059 15.8 0.0 1.5 1 0 0 1 1 1 1 DTW domain DnaJ-X PF14308.1 KFH44865.1 - 8.1e-72 240.7 0.2 8.1e-72 240.7 0.1 2.7 3 2 1 4 4 4 1 X-domain of DnaJ-containing DnaJ PF00226.26 KFH44865.1 - 1.9e-26 91.5 1.0 6.7e-26 89.8 0.7 2.0 1 0 0 1 1 1 1 DnaJ domain Herpes_LP PF03363.8 KFH44865.1 - 0.028 14.0 5.1 0.062 12.8 3.5 1.5 1 0 0 1 1 1 0 Herpesvirus leader protein WD40 PF00400.27 KFH44867.1 - 2.2e-12 46.3 1.4 0.026 14.4 0.0 7.1 6 1 0 6 6 6 3 WD domain, G-beta repeat PQQ_2 PF13360.1 KFH44867.1 - 0.00023 20.6 0.8 0.0015 18.0 0.4 2.3 1 1 1 2 2 2 1 PQQ-like domain Ada_Zn_binding PF02805.11 KFH44868.1 - 7.8e-32 108.6 7.5 1.2e-31 108.0 5.2 1.3 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_18 PF12833.2 KFH44868.1 - 3.9e-06 26.8 0.4 9.2e-06 25.6 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.18 KFH44868.1 - 5.6e-06 26.0 0.0 1.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family ketoacyl-synt PF00109.21 KFH44869.1 - 4.4e-62 209.8 0.0 1e-61 208.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KFH44869.1 - 8.7e-57 191.6 0.0 3e-56 189.9 0.0 2.0 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 KFH44869.1 - 4e-55 187.0 3.2 3e-54 184.1 0.7 2.9 3 0 0 3 3 3 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KFH44869.1 - 8.4e-53 179.7 0.5 6.2e-43 147.3 0.1 2.5 2 0 0 2 2 2 2 Acyl transferase domain adh_short PF00106.20 KFH44869.1 - 2.9e-44 150.9 0.0 2.9e-44 150.9 0.0 3.5 6 0 0 6 6 6 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KFH44869.1 - 2.3e-33 114.5 0.0 6e-33 113.2 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KFH44869.1 - 8.8e-18 64.1 0.0 4.5e-17 61.8 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFH44869.1 - 1.3e-06 28.1 0.1 3e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 KFH44869.1 - 1.4e-05 25.2 0.1 3.3e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 KFH44869.1 - 0.18 10.4 0.0 0.37 9.4 0.0 1.5 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Mannosyl_trans PF05007.8 KFH44870.1 - 8.1e-78 261.6 14.0 1.1e-77 261.2 9.7 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 KFH44870.1 - 8.6e-10 38.0 15.1 1.4e-08 34.0 10.5 2.2 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 KFH44870.1 - 5e-07 29.4 19.2 5e-07 29.4 13.3 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF2029) Bromodomain PF00439.20 KFH44871.1 - 5.1e-26 90.4 0.6 1.2e-25 89.2 0.4 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 KFH44871.1 - 1.3e-09 38.1 0.3 3.6e-09 36.6 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFH44871.1 - 5.5e-09 35.9 0.2 2e-08 34.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family DUF3353 PF11833.3 KFH44872.1 - 0.11 11.9 0.1 0.27 10.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) NMT_C PF02799.10 KFH44873.1 - 2.8e-74 248.6 0.1 4.2e-74 248.0 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 KFH44873.1 - 7.2e-71 237.0 0.0 1.2e-70 236.3 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.1 KFH44873.1 - 4.6e-06 26.5 0.0 0.0003 20.6 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KFH44873.1 - 0.022 14.9 0.0 0.21 11.7 0.0 2.4 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain DUF328 PF03883.9 KFH44873.1 - 0.17 11.1 1.9 0.34 10.1 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF328) DUF4407 PF14362.1 KFH44873.1 - 0.38 9.6 7.8 0.57 9.0 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HSP90 PF00183.13 KFH44873.1 - 1.2 7.4 5.6 1.7 6.9 3.9 1.2 1 0 0 1 1 1 0 Hsp90 protein DUF2201_N PF13203.1 KFH44873.1 - 1.3 8.1 7.6 1.9 7.5 5.3 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain PGA2 PF07543.7 KFH44873.1 - 6.4 6.5 11.3 2.9 7.6 5.9 1.8 2 0 0 2 2 2 0 Protein trafficking PGA2 UPF0197 PF05251.7 KFH44874.1 - 0.059 13.6 7.1 0.38 11.0 4.9 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0197) DUF2627 PF11118.3 KFH44874.1 - 1.3 9.1 4.4 0.69 10.0 1.7 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2627) Tri3 PF07428.6 KFH44875.1 - 0.00026 19.8 0.0 0.22 10.2 0.0 2.1 1 1 1 2 2 2 2 15-O-acetyltransferase Tri3 AATase PF07247.7 KFH44875.1 - 0.006 15.1 0.0 0.0089 14.6 0.0 1.2 1 0 0 1 1 1 1 Alcohol acetyltransferase Nop14 PF04147.7 KFH44878.1 - 0.074 10.9 5.1 0.069 11.0 3.5 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KFH44878.1 - 0.12 10.3 5.7 0.14 10.1 4.0 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 KFH44878.1 - 0.45 9.5 4.0 0.48 9.4 2.7 1.1 1 0 0 1 1 1 0 BUD22 Sigma70_ner PF04546.8 KFH44878.1 - 0.45 10.0 5.0 0.59 9.7 3.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.7 KFH44878.1 - 5.9 6.0 13.6 7.1 5.7 9.4 1.1 1 0 0 1 1 1 0 NOA36 protein Cyt-b5 PF00173.23 KFH44880.1 - 5.3e-15 54.9 0.0 1e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AA_permease PF00324.16 KFH44881.1 - 4.7e-94 315.3 36.4 5.6e-94 315.1 25.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFH44881.1 - 5.9e-24 84.3 37.4 7.8e-24 83.9 25.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 KFH44881.1 - 0.028 14.1 13.5 1.7 8.3 0.7 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF1772) ILVD_EDD PF00920.16 KFH44882.1 - 2.7e-142 474.8 0.0 9.1e-118 393.9 0.0 2.0 2 0 0 2 2 2 2 Dehydratase family HTH_38 PF13936.1 KFH44884.1 - 0.054 13.0 0.3 0.47 10.0 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Taeniidae_ag PF05596.6 KFH44884.1 - 0.11 12.3 0.0 4.1 7.2 0.0 2.4 2 0 0 2 2 2 0 Taeniidae antigen GIIM PF08388.6 KFH44884.1 - 0.14 12.0 0.1 13 5.6 0.0 2.4 2 0 0 2 2 2 0 Group II intron, maturase-specific domain Grp1_Fun34_YaaH PF01184.14 KFH44886.1 - 1.2e-84 282.8 12.7 1.4e-84 282.6 8.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family HIG_1_N PF04588.8 KFH44887.1 - 5e-20 70.9 0.6 1.4e-19 69.5 0.1 2.0 2 0 0 2 2 2 1 Hypoxia induced protein conserved region DUF2637 PF10935.3 KFH44887.1 - 0.052 13.4 0.4 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2637) DUF4407 PF14362.1 KFH44887.1 - 0.093 11.6 13.3 0.15 10.9 9.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Rifin_STEVOR PF02009.11 KFH44887.1 - 0.9 9.1 7.6 1.3 8.6 5.3 1.2 1 0 0 1 1 1 0 Rifin/stevor family DUF2514 PF10721.4 KFH44887.1 - 1.1 8.9 20.7 1.8 8.2 6.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) SHR3_chaperone PF08229.6 KFH44887.1 - 3.9 6.3 9.7 7.9 5.3 2.0 2.5 2 1 0 2 2 2 0 ER membrane protein SH3 ATP-synt_E PF05680.7 KFH44887.1 - 5.4 7.0 18.1 0.35 10.8 1.7 2.5 2 0 0 2 2 2 0 ATP synthase E chain zf-RanBP PF00641.13 KFH44888.1 - 0.041 13.0 1.5 0.041 13.0 1.0 2.5 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others IBR PF01485.16 KFH44888.1 - 0.25 11.2 8.0 0.72 9.7 5.6 1.8 1 1 0 1 1 1 0 IBR domain DZR PF12773.2 KFH44888.1 - 0.38 10.6 6.7 9 6.1 4.6 2.5 1 1 0 1 1 1 0 Double zinc ribbon C6_DPF PF10170.4 KFH44888.1 - 0.43 10.6 4.2 0.99 9.5 2.9 1.5 1 0 0 1 1 1 0 Cysteine-rich domain Zn-ribbon_8 PF09723.5 KFH44888.1 - 0.66 9.9 9.5 7.3 6.6 3.4 2.4 2 0 0 2 2 2 0 Zinc ribbon domain NAPRTase PF04095.11 KFH44889.1 - 9.9e-50 169.0 0.0 1.6e-49 168.4 0.0 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family DUF4013 PF13197.1 KFH44891.1 - 1.9e-05 24.0 1.8 2.7e-05 23.5 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4013) Ribophorin_II PF05817.9 KFH44892.1 - 7.6e-18 64.0 0.4 1.1e-17 63.4 0.2 1.3 1 1 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II DAO PF01266.19 KFH44893.1 - 3.7e-27 95.1 2.2 3.9e-26 91.8 1.6 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFH44893.1 - 0.00025 21.0 0.1 0.00081 19.3 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KFH44893.1 - 0.00035 19.5 0.2 0.00041 19.3 0.1 1.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KFH44893.1 - 0.0045 17.3 0.2 0.0097 16.2 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFH44893.1 - 0.02 13.9 0.1 0.036 13.1 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 KFH44893.1 - 0.065 12.3 1.4 0.11 11.5 0.1 2.0 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.9 KFH44893.1 - 0.068 13.0 0.3 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MT0933_antitox PF14013.1 KFH44895.1 - 0.0093 16.0 0.1 0.038 14.0 0.1 2.1 1 0 0 1 1 1 1 MT0933-like antitoxin protein F-box-like PF12937.2 KFH44896.1 - 0.002 17.8 1.2 0.0053 16.4 0.0 2.4 2 0 0 2 2 2 1 F-box-like DHDPS PF00701.17 KFH44897.1 - 3e-41 140.9 0.0 3.5e-41 140.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family zf-RING_2 PF13639.1 KFH44898.1 - 1.2e-10 41.0 5.5 5.6e-10 38.8 2.3 2.5 2 0 0 2 2 2 1 Ring finger domain zf-Apc11 PF12861.2 KFH44898.1 - 4e-06 26.5 1.9 4e-06 26.5 1.3 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 KFH44898.1 - 9.1e-05 22.4 1.4 9.1e-05 22.4 1.0 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KFH44898.1 - 9.5e-05 22.3 4.4 9.5e-05 22.3 3.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SWIM PF04434.12 KFH44898.1 - 0.00039 19.8 0.2 0.00076 18.9 0.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger zf-RING_5 PF14634.1 KFH44898.1 - 0.00043 19.9 3.1 0.00043 19.9 2.2 2.7 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_4 PF14570.1 KFH44898.1 - 0.00098 18.6 4.5 0.00098 18.6 3.1 1.7 2 0 0 2 2 1 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 KFH44898.1 - 0.0019 18.1 5.7 0.0019 18.1 3.9 2.3 2 1 0 2 2 2 1 FANCL C-terminal domain PHD PF00628.24 KFH44898.1 - 0.0027 17.3 5.3 0.0049 16.5 3.7 1.5 1 0 0 1 1 1 1 PHD-finger zf-C3HC4_3 PF13920.1 KFH44898.1 - 0.0038 16.8 1.7 0.0038 16.8 1.2 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 KFH44898.1 - 0.015 15.0 5.6 0.15 11.8 1.0 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 C1_1 PF00130.17 KFH44898.1 - 0.024 14.3 1.9 0.03 14.0 0.5 1.8 2 0 0 2 2 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RINGv PF12906.2 KFH44898.1 - 2.5 8.2 10.4 0.3 11.1 4.2 1.7 2 0 0 2 2 2 0 RING-variant domain ATAD4 PF15321.1 KFH44899.1 - 0.048 14.6 8.6 0.12 13.3 0.2 3.9 4 0 0 4 4 4 0 ATPase family AAA domain containing 4 3Beta_HSD PF01073.14 KFH44900.1 - 1.7e-13 49.9 0.0 5.5e-13 48.2 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KFH44900.1 - 1.4e-11 44.3 0.0 1.8e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KFH44900.1 - 2.3e-09 36.5 0.1 3.7e-07 29.3 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 KFH44900.1 - 1.8e-08 34.6 0.0 7.8e-08 32.5 0.0 2.0 2 1 0 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KFH44900.1 - 0.0002 20.3 0.0 0.00031 19.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 KFH44900.1 - 0.00034 19.9 0.1 0.00075 18.8 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 KFH44900.1 - 0.0037 17.1 0.1 0.035 14.0 0.1 2.3 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 KFH44900.1 - 0.054 12.3 0.0 0.15 10.9 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain KR PF08659.5 KFH44900.1 - 0.13 11.9 0.4 14 5.2 0.0 2.3 2 0 0 2 2 2 0 KR domain Glyco_hydro_12 PF01670.11 KFH44902.1 - 2.1e-10 40.5 0.6 3.3e-10 39.9 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 SQS_PSY PF00494.14 KFH44903.1 - 2.7e-40 138.3 0.0 3.9e-40 137.8 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase Sds3 PF08598.6 KFH44905.1 - 0.008 15.7 0.1 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 Sds3-like HLH PF00010.21 KFH44907.1 - 6.5e-12 44.9 0.4 1.4e-11 43.8 0.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3543 PF12063.3 KFH44908.1 - 7.1e-87 290.5 0.5 1.1e-86 289.8 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 KFH44908.1 - 7.6e-61 205.5 0.0 1.3e-60 204.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH44908.1 - 4.1e-41 140.7 0.0 8.3e-41 139.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KFH44908.1 - 0.22 10.2 0.0 0.35 9.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 KFH44909.1 - 1e-53 182.1 0.0 1.4e-53 181.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH44909.1 - 2.3e-23 82.5 0.0 3.4e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KFH44909.1 - 4.8e-11 42.6 0.0 1.1e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 KFH44909.1 - 4.8e-05 22.4 0.0 0.0029 16.6 0.0 2.2 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.9 KFH44909.1 - 0.042 12.9 0.0 0.089 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Acyl-CoA_dh_1 PF00441.19 KFH44910.1 - 7.4e-33 113.7 5.0 1.5e-32 112.7 3.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFH44910.1 - 1.1e-19 71.0 0.2 3.1e-19 69.6 0.2 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KFH44910.1 - 2.5e-14 53.6 4.7 2.5e-14 53.6 3.3 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFH44910.1 - 1.1e-13 50.4 0.6 3.3e-13 48.9 0.4 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain CLTH PF10607.4 KFH44912.1 - 3.2e-28 98.2 0.0 5.3e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 KFH44912.1 - 0.001 18.7 0.1 0.0049 16.5 0.0 2.2 2 0 0 2 2 2 1 LisH AcetylCoA_hydro PF02550.10 KFH44913.1 - 1.8e-47 161.6 0.0 2.8e-47 161.0 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 KFH44913.1 - 6.8e-39 133.0 0.0 1e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain RNA_pol_I_A49 PF06870.7 KFH44914.1 - 3.4e-74 249.7 1.2 3.8e-74 249.5 0.8 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor NDUF_B12 PF08122.7 KFH44915.1 - 5.8e-14 51.5 0.5 9.1e-14 50.9 0.4 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Chitin_bind_3 PF03067.10 KFH44916.1 - 8.5e-08 32.6 0.0 9.6e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Chitin binding domain Pribosyltran PF00156.22 KFH44917.1 - 1.5e-09 37.6 0.1 7.8e-09 35.3 0.1 1.9 1 1 0 1 1 1 1 Phosphoribosyl transferase domain PCNP PF15473.1 KFH44918.1 - 0.93 9.7 4.0 0.64 10.3 0.1 2.5 2 1 0 2 2 2 0 PEST, proteolytic signal-containing nuclear protein family 2OG-FeII_Oxy PF03171.15 KFH44919.1 - 4.7e-15 55.6 0.0 6.9e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KFH44919.1 - 1.2e-08 35.4 0.0 2.1e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal dCMP_cyt_deam_1 PF00383.17 KFH44920.1 - 1.8e-06 27.5 0.0 2.4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DUF2431 PF10354.4 KFH44922.1 - 4.1e-45 153.7 0.0 3.4e-30 105.2 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF2431) Mito_fiss_reg PF05308.6 KFH44922.1 - 0.0052 16.1 2.9 0.0052 16.1 2.0 1.6 2 0 0 2 2 2 1 Mitochondrial fission regulator Nop14 PF04147.7 KFH44922.1 - 0.052 11.4 5.4 0.094 10.6 3.7 1.3 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 KFH44922.1 - 0.081 12.5 5.3 0.16 11.5 3.7 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 KFH44922.1 - 0.16 11.5 5.0 0.26 10.8 3.4 1.4 1 0 0 1 1 1 0 Nucleoplasmin CAP_N PF01213.14 KFH44922.1 - 1.4 8.1 9.7 2.6 7.2 6.7 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal NOA36 PF06524.7 KFH44922.1 - 4.6 6.3 11.2 11 5.2 7.8 1.6 1 0 0 1 1 1 0 NOA36 protein TRAP_alpha PF03896.11 KFH44922.1 - 6.7 5.6 7.0 11 4.9 4.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit GCR1_C PF12550.3 KFH44923.1 - 1.1e-12 47.6 0.2 1.9e-12 46.8 0.1 1.4 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Leu_zip PF15294.1 KFH44923.1 - 0.017 14.2 0.4 0.03 13.4 0.3 1.3 1 0 0 1 1 1 0 Leucine zipper Herpes_BLRF2 PF05812.7 KFH44923.1 - 0.054 13.3 0.6 6.6 6.5 0.7 3.2 1 1 2 3 3 3 0 Herpesvirus BLRF2 protein DUF904 PF06005.7 KFH44923.1 - 0.12 12.6 3.5 3.2 8.0 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF904) IncA PF04156.9 KFH44923.1 - 0.23 11.0 3.3 0.53 9.8 2.3 1.5 1 0 0 1 1 1 0 IncA protein DivIVA PF05103.8 KFH44923.1 - 0.29 11.1 2.2 0.43 10.6 0.9 1.8 2 0 0 2 2 2 0 DivIVA protein ADIP PF11559.3 KFH44923.1 - 0.29 11.0 7.2 4.3 7.2 0.2 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TSC22 PF01166.13 KFH44923.1 - 0.44 10.5 4.0 59 3.7 0.1 3.9 2 2 2 4 4 4 0 TSC-22/dip/bun family DivIC PF04977.10 KFH44923.1 - 5.4 6.5 6.9 4.3 6.8 0.6 2.7 3 0 0 3 3 3 0 Septum formation initiator Vps51 PF08700.6 KFH44924.1 - 2.1e-12 46.7 0.0 6.8e-12 45.0 0.0 1.9 1 0 0 1 1 1 1 Vps51/Vps67 Abhydrolase_1 PF00561.15 KFH44925.1 - 1.2e-29 103.4 0.0 3.1e-28 98.8 0.0 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KFH44925.1 - 6.6e-16 58.8 0.0 9.4e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KFH44925.1 - 0.002 18.0 0.0 0.0051 16.6 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_5 PF12695.2 KFH44925.1 - 0.0037 17.0 0.0 0.014 15.1 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family ketoacyl-synt PF00109.21 KFH44926.1 - 1.9e-64 217.6 0.0 2.3e-64 217.3 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.18 KFH44926.1 - 1.1e-05 24.6 0.0 1.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 KFH44926.1 - 0.0005 19.6 0.2 0.001 18.7 0.1 1.5 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Voltage_CLC PF00654.15 KFH44927.1 - 2e-91 306.6 20.6 2e-91 306.6 14.3 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel TAT_signal PF10518.4 KFH44927.1 - 0.013 15.4 3.4 0.013 15.4 2.4 2.4 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence p450 PF00067.17 KFH44928.1 - 1.1e-51 175.7 0.0 1.5e-51 175.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KFH44930.1 - 7.4e-56 189.5 0.0 9.4e-56 189.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ThiF PF00899.16 KFH44931.1 - 1.4e-11 44.3 0.0 2.2e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 ThiF family Cornichon PF03311.9 KFH44931.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Cornichon protein Lin-8 PF03353.10 KFH44932.1 - 0.03 13.6 3.8 0.048 12.9 2.6 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist GSIII_N PF12437.3 KFH44932.1 - 0.088 12.1 0.1 0.81 9.0 0.0 2.1 2 0 0 2 2 2 0 Glutamine synthetase type III N terminal GSDH PF07995.6 KFH44933.1 - 0.00086 18.4 0.1 0.002 17.3 0.0 1.5 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase AMP-binding PF00501.23 KFH44934.1 - 2.1e-67 227.3 0.0 2.8e-67 226.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 KFH44934.1 - 7.5e-07 28.2 2.1 1.3e-06 27.5 1.5 1.2 1 0 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.1 KFH44934.1 - 1e-05 26.3 0.1 2.4e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FAD_binding_3 PF01494.14 KFH44935.1 - 1.7e-07 30.6 2.4 0.054 12.5 0.1 3.2 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 KFH44935.1 - 0.0027 17.7 0.8 0.017 15.1 0.1 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_Gly3P_dh_N PF01210.18 KFH44935.1 - 0.09 12.5 0.2 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus MFS_1 PF07690.11 KFH44936.1 - 2.3e-06 26.6 35.0 2.5e-05 23.1 21.3 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_16 PF00722.16 KFH44937.1 - 9.8e-10 38.0 0.0 2.2e-09 36.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 G0-G1_switch_2 PF15103.1 KFH44938.1 - 0.027 14.7 0.1 0.079 13.2 0.0 1.7 2 0 0 2 2 2 0 G0/G1 switch protein 2 Zn_clus PF00172.13 KFH44939.1 - 0.47 10.3 7.9 1.2 9.1 5.5 1.7 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain APH PF01636.18 KFH44940.1 - 2.3e-16 60.2 0.0 3.6e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFH44940.1 - 0.022 14.3 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase CENP-P PF13096.1 KFH44941.1 - 0.073 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P FdhE PF04216.7 KFH44941.1 - 0.15 11.7 0.7 0.3 10.7 0.5 1.4 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Fungal_trans PF04082.13 KFH44942.1 - 6.1e-34 117.0 0.0 1.3e-33 116.0 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH44942.1 - 4e-06 26.6 7.2 7.8e-06 25.6 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.2 KFH44943.1 - 8.5e-06 25.4 0.9 1.3e-05 24.8 0.1 1.8 2 0 0 2 2 2 1 F-box-like CAF1 PF04857.15 KFH44944.1 - 1.9e-69 233.9 0.0 2.4e-69 233.5 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease RFX_DNA_binding PF02257.10 KFH44944.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain APH PF01636.18 KFH44945.1 - 1e-13 51.5 0.1 1.8e-13 50.8 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Beta_helix PF13229.1 KFH44945.1 - 0.00061 19.5 15.5 0.001 18.8 10.7 1.3 1 0 0 1 1 1 1 Right handed beta helix region Fructosamin_kin PF03881.9 KFH44945.1 - 0.15 11.0 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase ECH PF00378.15 KFH44946.1 - 4.3e-21 75.1 0.0 4.7e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family WD-3 PF09765.4 KFH44947.1 - 0.16 11.1 0.7 0.26 10.5 0.5 1.2 1 0 0 1 1 1 0 WD-repeat region Oxidored-like PF09791.4 KFH44948.1 - 6.4e-25 86.3 3.7 6.4e-25 86.3 2.6 2.5 3 0 0 3 3 3 1 Oxidoreductase-like protein, N-terminal LZ_Tnp_IS66 PF13007.2 KFH44948.1 - 9.3 6.9 9.0 19 5.9 4.3 2.7 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain Acetyltransf_2 PF00797.12 KFH44949.1 - 1.6e-30 106.4 0.0 1.9e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase DUF2427 PF10348.4 KFH44950.1 - 7e-09 35.2 1.4 1.6e-08 34.0 1.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.11 KFH44950.1 - 7.5e-06 25.8 12.1 1.4e-05 24.9 8.4 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.12 KFH44950.1 - 5.6e-05 23.0 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 DOMON domain DUF2306 PF10067.4 KFH44950.1 - 0.25 11.5 14.2 0.48 10.5 1.9 2.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2306) CoA_binding_3 PF13727.1 KFH44950.1 - 0.91 9.3 5.4 0.69 9.7 0.1 2.2 1 1 1 2 2 2 0 CoA-binding domain SRI PF08236.6 KFH44952.1 - 4.8e-24 84.1 5.8 1.1e-23 82.9 4.1 1.7 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.23 KFH44952.1 - 2.4e-21 76.7 0.3 2.4e-21 76.7 0.2 3.2 3 2 0 3 3 3 1 SET domain Med26 PF08711.6 KFH44952.1 - 3.9e-06 26.2 0.2 9.1e-06 25.0 0.1 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain WW PF00397.21 KFH44952.1 - 5.3e-05 22.9 2.3 0.00012 21.8 1.6 1.7 1 0 0 1 1 1 1 WW domain Myb_DNA-binding PF00249.26 KFH44953.1 - 0.0048 16.9 2.2 0.055 13.5 1.1 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain DPM3 PF08285.6 KFH44954.1 - 5.3e-32 109.5 0.0 5.8e-32 109.3 0.0 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Cytochrom_B_N PF00033.14 KFH44954.1 - 0.054 12.8 0.1 0.062 12.6 0.1 1.1 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB 2OG-FeII_Oxy PF03171.15 KFH44955.1 - 2.4e-07 30.9 0.0 5.4e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KFH44955.1 - 0.00013 22.4 0.0 0.00022 21.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal p450 PF00067.17 KFH44956.1 - 4.3e-53 180.4 0.0 5.7e-53 180.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF59 PF01883.14 KFH44956.1 - 0.083 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF59 E1-E2_ATPase PF00122.15 KFH44958.1 - 3.7e-59 199.5 3.3 4.4e-59 199.3 1.2 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFH44958.1 - 1.7e-45 154.7 6.3 1.7e-45 154.7 4.4 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFH44958.1 - 2.3e-32 113.1 0.0 6e-32 111.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFH44958.1 - 7.3e-19 67.5 0.1 1.6e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KFH44958.1 - 2.1e-14 54.1 0.0 4.2e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFH44958.1 - 5.3e-12 45.0 0.0 1.2e-09 37.4 0.0 2.7 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KFH44958.1 - 0.00037 20.1 0.8 0.00058 19.5 0.1 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase YjgP_YjgQ PF03739.9 KFH44958.1 - 0.0034 16.1 1.7 0.0066 15.2 1.2 1.4 1 0 0 1 1 1 1 Predicted permease YjgP/YjgQ family Transferase PF02458.10 KFH44959.1 - 1.3e-12 46.9 0.0 1.7e-11 43.2 0.0 2.5 2 1 0 2 2 2 1 Transferase family Sas10 PF09368.5 KFH44960.1 - 2.9e-28 97.8 7.1 2.9e-28 97.8 4.9 2.6 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 KFH44960.1 - 1.4e-10 41.2 0.0 4.6e-10 39.5 0.0 1.9 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Carn_acyltransf PF00755.15 KFH44962.1 - 1.8e-78 264.1 0.0 2.6e-78 263.6 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Acyl_transf_1 PF00698.16 KFH44962.1 - 1e-54 186.0 0.8 2.2e-54 184.9 0.5 1.6 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KFH44962.1 - 7.5e-46 156.6 0.0 2e-45 155.2 0.0 1.8 1 1 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 KFH44962.1 - 1.7e-39 135.3 0.0 6.8e-39 133.3 0.0 2.1 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.17 KFH44962.1 - 6e-37 126.1 0.1 2.7e-36 123.9 0.0 2.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 KFH44962.1 - 4.4e-33 114.5 0.1 4.4e-33 114.5 0.0 3.6 5 0 0 5 5 3 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.1 KFH44962.1 - 3.6e-08 34.3 0.0 3e-07 31.3 0.0 2.8 2 0 0 2 2 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 KFH44962.1 - 5.9e-08 32.8 0.8 1.6e-07 31.4 0.5 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N PF00107.21 KFH44962.1 - 1.5e-07 31.0 0.1 6.3e-07 28.9 0.1 2.1 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ketoacyl-synt PF00109.21 KFH44962.1 - 1.4e-05 24.7 0.1 3.7e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ADH_N PF08240.7 KFH44962.1 - 0.0026 17.4 0.3 0.006 16.3 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Polysacc_synt_2 PF02719.10 KFH44962.1 - 0.0028 16.6 0.0 0.0064 15.4 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_12 PF08242.7 KFH44962.1 - 0.0038 17.6 0.0 0.031 14.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH44962.1 - 0.18 11.3 0.0 0.45 10.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Dpy19 PF10034.4 KFH44962.1 - 4.6 5.2 0.0 6.8 4.7 0.0 1.1 1 0 0 1 1 1 0 Q-cell neuroblast polarisation Aminotran_3 PF00202.16 KFH44963.1 - 1.7e-94 316.4 0.0 2.1e-94 316.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KFH44963.1 - 0.012 14.6 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Lsr2 PF11774.3 KFH44964.1 - 0.0024 17.8 0.1 0.0034 17.2 0.1 1.3 1 0 0 1 1 1 1 Lsr2 Aida_N PF08910.5 KFH44964.1 - 0.0094 16.1 0.5 0.0094 16.1 0.3 1.8 2 0 0 2 2 2 1 Aida N-terminus tRNA-synt_1c PF00749.16 KFH44964.1 - 0.048 12.3 0.8 0.062 11.9 0.6 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain FAD_binding_4 PF01565.18 KFH44965.1 - 1.5e-19 69.8 3.3 2.8e-19 68.9 2.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFH44965.1 - 3.7e-10 39.5 0.6 8.1e-10 38.4 0.4 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KFH44965.1 - 0.06 12.4 0.0 0.092 11.8 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Aldo_ket_red PF00248.16 KFH44966.1 - 2.7e-52 177.3 0.0 3.3e-52 177.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Mob1_phocein PF03637.12 KFH44967.1 - 3.4e-37 127.7 1.3 7.7e-21 74.5 0.0 2.1 2 0 0 2 2 2 2 Mob1/phocein family ATP-synt_10 PF05176.9 KFH44968.1 - 1e-86 290.3 0.0 1.3e-86 290.0 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein V-SNARE_C PF12352.3 KFH44969.1 - 3.1e-10 39.9 0.2 3.1e-10 39.9 0.1 2.9 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus P16-Arc PF04699.9 KFH44969.1 - 0.041 13.9 1.3 0.076 13.0 0.9 1.4 1 0 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) TAP35_44 PF07265.6 KFH44969.1 - 0.071 12.8 0.2 0.21 11.3 0.0 1.9 2 0 0 2 2 2 0 Tapetum specific protein TAP35/TAP44 CorA PF01544.13 KFH44969.1 - 0.074 12.0 10.6 0.16 10.9 5.9 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Surfac_D-trimer PF09006.6 KFH44969.1 - 0.11 12.2 0.1 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation IncA PF04156.9 KFH44969.1 - 2.1 7.8 13.0 1.9 8.0 7.7 1.7 1 1 1 2 2 2 0 IncA protein APG6 PF04111.7 KFH44969.1 - 4.1 6.3 8.4 2.2 7.2 4.5 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 FUSC PF04632.7 KFH44969.1 - 7.7 4.8 6.2 11 4.3 4.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3712 PF12505.3 KFH44970.1 - 8.8e-24 83.9 4.2 1.1e-23 83.6 1.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) Prominin PF05478.6 KFH44970.1 - 0.007 13.9 0.0 0.013 13.1 0.0 1.5 1 0 0 1 1 1 1 Prominin Baculo_11_kDa PF06143.6 KFH44970.1 - 0.024 13.9 0.6 0.053 12.8 0.4 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF805 PF05656.9 KFH44970.1 - 0.039 13.7 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF805) RED_N PF07808.8 KFH44971.1 - 1.3e-09 37.6 8.1 1.3e-09 37.6 5.6 2.1 2 0 0 2 2 2 1 RED-like protein N-terminal region Cyt_c_ox_IV PF12270.3 KFH44971.1 - 3.4 7.4 7.9 1.1 9.0 0.1 2.9 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV Stk19 PF10494.4 KFH44972.1 - 4.1e-38 131.2 0.0 5.4e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 MarR_2 PF12802.2 KFH44972.1 - 0.0016 18.0 0.7 0.007 16.0 0.5 2.1 2 0 0 2 2 2 1 MarR family Mito_fiss_reg PF05308.6 KFH44972.1 - 0.036 13.4 5.7 0.063 12.6 4.0 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator SAGA-Tad1 PF12767.2 KFH44972.1 - 0.85 9.2 4.1 1.5 8.4 2.8 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit ORC6 PF05460.8 KFH44972.1 - 6.2 5.8 8.6 11 5.0 5.9 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Arf PF00025.16 KFH44973.1 - 2.6e-56 189.5 0.5 2.4e-38 131.1 0.0 2.0 1 1 1 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.5 KFH44973.1 - 4e-09 35.9 0.1 0.00031 20.0 0.0 2.1 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit Ras PF00071.17 KFH44973.1 - 0.00042 19.7 0.0 0.11 11.8 0.0 2.0 2 0 0 2 2 2 2 Ras family G-alpha PF00503.15 KFH44973.1 - 0.00081 18.1 0.1 0.25 9.9 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KFH44973.1 - 0.00083 18.5 0.2 0.019 14.0 0.0 2.0 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KFH44973.1 - 0.0013 19.2 0.2 0.3 11.5 0.0 2.2 1 1 1 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 KFH44973.1 - 0.032 14.2 0.4 0.41 10.6 0.2 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase 6PF2K PF01591.13 KFH44973.1 - 0.045 12.8 0.6 0.1 11.6 0.0 1.7 2 0 0 2 2 2 0 6-phosphofructo-2-kinase AAA_33 PF13671.1 KFH44973.1 - 0.054 13.3 0.2 0.14 12.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 KFH44973.1 - 0.071 12.5 0.1 0.72 9.2 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Mito_carr PF00153.22 KFH44974.1 - 2.5e-61 203.4 0.1 2.3e-20 72.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-C2H2_4 PF13894.1 KFH44975.1 - 0.0016 18.6 4.8 0.27 11.6 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KFH44975.1 - 0.0018 18.5 4.1 0.23 11.8 0.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFH44975.1 - 0.05 13.9 0.6 0.12 12.7 0.0 2.0 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 KFH44975.1 - 0.21 11.5 2.8 11 6.0 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Ribosomal_L6e PF01159.14 KFH44976.1 - 1.6e-35 121.5 0.3 3e-35 120.7 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L6e AAA_22 PF13401.1 KFH44977.1 - 1e-13 51.5 0.1 2.9e-13 50.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 KFH44977.1 - 1.2e-11 45.0 1.0 1.4e-10 41.4 0.1 2.8 2 2 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 KFH44977.1 - 5.7e-10 39.5 0.0 3.5e-09 36.9 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.6 KFH44977.1 - 4.4e-05 23.1 0.1 0.00023 20.8 0.0 2.2 2 0 0 2 2 2 1 CDC6, C terminal NB-ARC PF00931.17 KFH44977.1 - 0.0007 18.5 0.0 0.0026 16.6 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain AAA_35 PF14516.1 KFH44977.1 - 0.0016 17.1 0.0 0.0027 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_14 PF13173.1 KFH44977.1 - 0.0016 18.3 0.0 0.0042 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 KFH44977.1 - 0.0029 16.6 0.0 0.0043 16.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 KFH44977.1 - 0.0061 16.2 0.0 0.028 14.1 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 KFH44977.1 - 0.0093 15.5 1.6 0.035 13.6 1.1 1.9 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KFH44977.1 - 0.0093 15.6 0.0 0.026 14.2 0.0 1.8 1 1 0 1 1 1 1 Archaeal ATPase AAA_32 PF13654.1 KFH44977.1 - 0.014 14.0 0.3 0.03 13.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KFH44977.1 - 0.025 14.7 0.0 0.068 13.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.1 KFH44977.1 - 0.032 13.8 1.3 0.17 11.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA12 PF10443.4 KFH44977.1 - 0.085 11.3 0.1 0.35 9.3 0.0 2.0 2 1 0 2 2 2 0 RNA12 protein AAA_5 PF07728.9 KFH44977.1 - 0.088 12.5 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Rrf2 PF02082.15 KFH44977.1 - 0.093 12.8 0.1 0.95 9.6 0.0 2.5 3 0 0 3 3 3 0 Transcriptional regulator KAP_NTPase PF07693.9 KFH44977.1 - 0.096 11.6 0.0 0.2 10.6 0.0 1.7 1 1 0 1 1 1 0 KAP family P-loop domain Torsin PF06309.6 KFH44977.1 - 0.099 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Torsin NTPase_1 PF03266.10 KFH44977.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 NTPase p450 PF00067.17 KFH44978.1 - 1.6e-76 257.7 0.0 2e-76 257.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HSCB_C PF07743.8 KFH44979.1 - 6.9e-17 61.6 7.2 6.9e-17 61.6 5.0 1.7 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 KFH44979.1 - 1.6e-08 34.1 0.0 3.1e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Ribosomal_L29 PF00831.18 KFH44980.1 - 5.4e-18 64.4 0.6 5.4e-18 64.4 0.4 1.8 2 1 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 KFH44980.1 - 0.032 14.4 1.5 0.039 14.1 1.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S9/S16 DUF2450 PF10475.4 KFH44980.1 - 0.081 11.8 1.0 0.091 11.6 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) SPATA24 PF15175.1 KFH44980.1 - 0.086 12.5 2.0 0.1 12.2 1.4 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 E1-E2_ATPase PF00122.15 KFH44981.1 - 4.9e-48 163.1 4.1 4.9e-48 163.1 2.9 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KFH44981.1 - 8.5e-24 85.1 4.5 1.4e-23 84.4 3.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFH44981.1 - 2.9e-13 50.3 0.0 5.5e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFH44981.1 - 0.11 12.0 0.3 3.7 7.0 0.1 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase DUF3405 PF11885.3 KFH44982.1 - 4e-205 681.7 0.1 2.3e-203 675.9 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) FancD2 PF14631.1 KFH44982.1 - 0.052 10.6 5.3 0.071 10.2 3.7 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease RR_TM4-6 PF06459.7 KFH44982.1 - 1.7 8.4 8.8 2.9 7.6 6.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RRM_1 PF00076.17 KFH44984.1 - 6.3e-14 51.3 0.2 1.6e-05 24.4 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH44984.1 - 2e-12 46.8 0.1 5.1e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH44984.1 - 5.9e-09 35.6 0.0 6e-08 32.4 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sulfate_transp PF00916.15 KFH44985.1 - 9.8e-33 113.3 0.2 2.2e-32 112.2 0.0 1.7 1 1 0 1 1 1 1 Sulfate transporter family cNMP_binding PF00027.24 KFH44985.1 - 4.9e-18 64.7 0.0 1e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 KFH44985.1 - 1.4e-10 40.6 0.0 2.6e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 STAS domain Proteasom_Rpn13 PF04683.8 KFH44987.1 - 8.1e-27 93.1 0.0 1.2e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor L27_2 PF09045.5 KFH44987.1 - 0.00091 18.7 0.2 0.0017 17.8 0.1 1.4 1 0 0 1 1 1 1 L27_2 CobT PF06213.7 KFH44987.1 - 1.2 8.1 8.0 1.8 7.6 5.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF3074 PF11274.3 KFH44990.1 - 7.9e-37 126.6 0.6 1.7e-36 125.5 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) DUF3829 PF12889.2 KFH44991.1 - 0.035 13.2 0.7 0.066 12.3 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3829) Img2 PF05046.9 KFH44991.1 - 0.061 13.5 0.6 0.26 11.5 0.4 2.2 1 1 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) DUF724 PF05266.9 KFH44991.1 - 0.54 9.8 11.2 0.2 11.2 4.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF724) DUF2315 PF10231.4 KFH44991.1 - 0.56 10.0 4.8 3.6 7.4 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2315) DUF1770 PF08589.5 KFH44991.1 - 0.74 10.4 6.4 3.3 8.3 4.4 2.4 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF1770) DUF2408 PF10303.4 KFH44991.1 - 0.88 9.6 8.4 1.8 8.6 2.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) AATF-Che1 PF13339.1 KFH44991.1 - 1.5 8.9 10.9 10 6.3 6.6 2.7 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Tup_N PF08581.5 KFH44991.1 - 1.8 8.8 7.6 15 5.8 4.1 3.0 1 1 1 2 2 2 0 Tup N-terminal IncA PF04156.9 KFH44991.1 - 1.8 8.1 11.3 5.4 6.5 7.5 2.0 1 1 0 1 1 1 0 IncA protein APG6 PF04111.7 KFH44991.1 - 2.3 7.2 12.4 0.25 10.3 5.4 1.7 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF972 PF06156.8 KFH44991.1 - 3.4 8.0 9.9 4.9 7.5 4.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF2968 PF11180.3 KFH44991.1 - 3.7 6.8 15.4 0.13 11.6 5.1 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF2968) FlxA PF14282.1 KFH44991.1 - 5.1 7.1 11.0 0.19 11.6 2.3 2.6 2 1 0 2 2 2 0 FlxA-like protein Mito_carr PF00153.22 KFH44992.1 - 3.2e-67 222.2 0.2 1.5e-21 75.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Zn_clus PF00172.13 KFH44993.1 - 1.6e-05 24.6 9.4 3.2e-05 23.7 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.1 KFH44994.1 - 1.1e-18 66.4 51.8 7.8e-07 29.0 0.2 7.8 8 1 0 8 8 8 4 Zinc-finger double domain zf-C2H2 PF00096.21 KFH44994.1 - 1.3e-12 47.2 56.6 0.00044 20.4 0.4 7.7 8 0 0 8 8 8 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFH44994.1 - 2.6e-07 30.4 56.3 0.048 13.9 0.1 8.0 8 0 0 8 8 8 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFH44994.1 - 5.5e-06 26.3 22.7 0.0017 18.4 1.7 5.5 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFH44994.1 - 0.00037 20.2 0.0 0.00037 20.2 0.0 5.0 6 0 0 6 6 6 2 C2H2-type zinc finger zf-met PF12874.2 KFH44994.1 - 0.0084 16.2 0.8 0.0084 16.2 0.5 4.8 4 0 0 4 4 4 1 Zinc-finger of C2H2 type GAGA PF09237.6 KFH44994.1 - 0.16 11.6 3.9 2.3 7.8 0.1 3.0 2 0 0 2 2 2 0 GAGA factor zf-C2HC_2 PF13913.1 KFH44994.1 - 0.73 9.5 9.8 2.1 8.1 0.2 3.9 4 0 0 4 4 4 0 zinc-finger of a C2HC-type EF1_GNE PF00736.14 KFH44995.1 - 3.6e-32 109.9 2.3 6.2e-32 109.1 1.6 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 KFH44995.1 - 1.5e-12 47.3 12.0 1.5e-12 47.3 8.3 2.2 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 KFH44995.1 - 2e-05 24.9 0.2 5.5e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFH44995.1 - 7.8e-05 22.5 0.3 0.00042 20.2 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain SART-1 PF03343.8 KFH44995.1 - 0.0056 15.0 0.7 0.0056 15.0 0.5 1.3 2 0 0 2 2 2 1 SART-1 family DUF3752 PF12572.3 KFH44995.1 - 0.089 12.9 5.1 0.14 12.2 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) YL1 PF05764.8 KFH44995.1 - 0.17 11.4 5.9 0.25 10.9 4.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein DNA_pol3_a_NII PF11490.3 KFH44995.1 - 4.4 6.9 5.6 18 4.9 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II Glyco_hydro_10 PF00331.15 KFH44996.1 - 2.9e-103 345.2 0.0 3.3e-103 345.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DUF4339 PF14237.1 KFH44996.1 - 0.051 13.1 0.1 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4339) EMP24_GP25L PF01105.19 KFH44997.1 - 4.9e-40 137.2 0.2 5.6e-40 137.0 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SHR3_chaperone PF08229.6 KFH44998.1 - 2.5e-59 199.5 0.0 3.2e-59 199.2 0.0 1.2 1 0 0 1 1 1 1 ER membrane protein SH3 FMN_dh PF01070.13 KFH44999.1 - 3.2e-103 345.3 0.0 3.8e-103 345.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KFH44999.1 - 3e-21 74.9 0.0 1e-20 73.2 0.0 2.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 KFH44999.1 - 3.6e-08 32.6 0.2 7.6e-05 21.7 0.1 2.3 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KFH44999.1 - 2.6e-07 29.9 0.1 4.8e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.16 KFH44999.1 - 0.0021 17.0 0.0 0.0031 16.5 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.16 KFH44999.1 - 0.0079 15.4 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.10 KFH44999.1 - 0.033 13.3 1.4 0.035 13.2 0.2 1.6 2 0 0 2 2 2 0 Nitronate monooxygenase Ribul_P_3_epim PF00834.14 KFH44999.1 - 0.098 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family TspO_MBR PF03073.10 KFH45000.1 - 7.6e-44 148.8 8.7 1e-43 148.4 6.0 1.2 1 0 0 1 1 1 1 TspO/MBR family IMS PF00817.15 KFH45001.1 - 1.7e-39 135.0 0.0 3.3e-39 134.0 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KFH45001.1 - 7.4e-18 64.7 0.0 1.5e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 KFH45001.1 - 2.2e-14 53.2 4.2 5.2e-07 29.5 0.1 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF4414) BRCT PF00533.21 KFH45001.1 - 0.00016 21.7 0.0 0.00034 20.6 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain HHH_5 PF14520.1 KFH45001.1 - 0.0029 17.7 0.1 0.0085 16.2 0.1 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain DUF1805 PF08827.6 KFH45001.1 - 0.041 13.6 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) MgtE_N PF03448.12 KFH45001.1 - 0.043 14.1 6.0 1.8 8.8 0.0 4.3 5 0 0 5 5 5 0 MgtE intracellular N domain IMS_HHH PF11798.3 KFH45001.1 - 0.053 13.5 0.4 0.31 11.1 0.0 2.6 2 0 0 2 2 2 0 IMS family HHH motif FliG_M PF14841.1 KFH45001.1 - 0.072 13.1 0.5 28 4.8 0.0 3.6 4 0 0 4 4 4 0 FliG middle domain Herpes_pp38 PF04846.8 KFH45002.1 - 0.07 12.4 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein Cullin PF00888.17 KFH45003.1 - 1.5e-46 159.1 0.0 2.6e-46 158.3 0.0 1.3 1 0 0 1 1 1 1 Cullin family APC2 PF08672.6 KFH45003.1 - 4.8e-19 68.3 0.0 9.9e-19 67.3 0.0 1.6 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 Peptidase_M49 PF03571.10 KFH45004.1 - 8.5e-226 750.2 0.0 1e-225 750.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 Arrestin_N PF00339.24 KFH45005.1 - 3.2e-18 65.9 0.1 1.9e-15 56.9 0.0 3.1 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain HCNGP PF07818.8 KFH45007.1 - 4.2e-30 103.6 0.0 5.5e-30 103.2 0.0 1.1 1 0 0 1 1 1 1 HCNGP-like protein Sld5 PF05916.6 KFH45008.1 - 1.5e-13 50.9 0.0 2.3e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Pkr1 PF08636.5 KFH45009.1 - 2.6e-33 113.8 3.9 3.3e-33 113.5 2.7 1.1 1 0 0 1 1 1 1 ER protein Pkr1 FHIPEP PF00771.15 KFH45009.1 - 0.017 13.4 0.0 0.021 13.2 0.0 1.0 1 0 0 1 1 1 0 FHIPEP family Trp_oprn_chp PF09534.5 KFH45009.1 - 0.042 13.4 0.1 0.053 13.1 0.1 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) AAA_33 PF13671.1 KFH45010.1 - 1.4e-14 54.1 0.0 1.9e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFH45010.1 - 6.1e-14 52.8 0.1 9.7e-14 52.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 KFH45010.1 - 6e-13 48.9 0.0 8e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.1 KFH45010.1 - 3.3e-11 43.6 0.0 7.4e-11 42.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KFH45010.1 - 1.9e-07 31.3 0.0 6.6e-07 29.5 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 KFH45010.1 - 9.4e-07 27.8 0.0 1.4e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_28 PF13521.1 KFH45010.1 - 8.5e-06 25.8 0.0 1.2e-05 25.3 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KFH45010.1 - 6.9e-05 23.0 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFH45010.1 - 0.00022 21.2 0.0 0.00056 19.9 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 KFH45010.1 - 0.00057 19.7 0.0 0.0012 18.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 KFH45010.1 - 0.00058 19.8 0.0 0.0024 17.7 0.0 2.1 1 1 0 1 1 1 1 Cytidylate kinase-like family RNA_helicase PF00910.17 KFH45010.1 - 0.00075 19.6 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 RNA helicase APS_kinase PF01583.15 KFH45010.1 - 0.00096 18.8 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_5 PF07728.9 KFH45010.1 - 0.0012 18.6 0.0 0.0023 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) PRK PF00485.13 KFH45010.1 - 0.0018 17.8 0.0 0.0037 16.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.7 KFH45010.1 - 0.0018 17.4 0.1 0.0045 16.1 0.0 1.7 1 1 0 1 1 1 1 Zeta toxin NACHT PF05729.7 KFH45010.1 - 0.0023 17.5 0.0 0.004 16.8 0.0 1.3 1 0 0 1 1 1 1 NACHT domain CobU PF02283.11 KFH45010.1 - 0.0024 17.2 0.0 0.0067 15.8 0.0 1.7 1 0 0 1 1 1 1 Cobinamide kinase / cobinamide phosphate guanyltransferase ABC_tran PF00005.22 KFH45010.1 - 0.003 17.8 0.0 0.0083 16.4 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_19 PF13245.1 KFH45010.1 - 0.0033 17.1 0.0 0.011 15.4 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain CoaE PF01121.15 KFH45010.1 - 0.0057 16.0 0.0 0.016 14.6 0.0 1.7 2 0 0 2 2 2 1 Dephospho-CoA kinase DNA_pol3_delta2 PF13177.1 KFH45010.1 - 0.0058 16.2 0.0 0.011 15.4 0.0 1.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit ADK PF00406.17 KFH45010.1 - 0.0091 15.8 0.1 1.1 9.1 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase Thymidylate_kin PF02223.12 KFH45010.1 - 0.01 15.2 0.0 0.97 8.7 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase Arch_ATPase PF01637.13 KFH45010.1 - 0.012 15.3 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Viral_helicase1 PF01443.13 KFH45010.1 - 0.019 14.5 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 KFH45010.1 - 0.022 13.7 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RuvB_N PF05496.7 KFH45010.1 - 0.025 13.6 0.3 0.049 12.6 0.0 1.6 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 KFH45010.1 - 0.036 13.2 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 KFH45010.1 - 0.039 13.4 0.0 0.077 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.10 KFH45010.1 - 0.042 13.5 0.0 0.075 12.7 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_PrkA PF08298.6 KFH45010.1 - 0.044 12.4 0.0 0.07 11.8 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain MobB PF03205.9 KFH45010.1 - 0.052 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 KFH45010.1 - 0.062 12.4 0.0 0.095 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 T2SE PF00437.15 KFH45010.1 - 0.068 12.0 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 KFH45010.1 - 0.09 12.3 0.1 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain RhoGEF PF00621.15 KFH45011.1 - 8.3e-34 117.0 0.0 1.5e-33 116.1 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.13 KFH45011.1 - 8.1e-12 45.1 0.5 8.1e-12 45.1 0.4 2.1 3 0 0 3 3 3 1 BAR domain Kinesin PF00225.18 KFH45012.1 - 1.1e-95 320.1 0.0 1.1e-95 320.1 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Spore_coat_CotO PF14153.1 KFH45012.1 - 0.075 12.4 5.5 0.16 11.4 3.8 1.5 1 0 0 1 1 1 0 Spore coat protein CotO ECIST_Cterm PF14784.1 KFH45012.1 - 0.089 12.7 0.2 17 5.3 0.0 2.4 2 0 0 2 2 2 0 C-terminal domain of the ECSIT protein TAFII55_N PF04658.8 KFH45013.1 - 3.4e-50 169.7 0.9 4.4e-50 169.3 0.0 1.6 2 0 0 2 2 2 1 TAFII55 protein conserved region Myc_N PF01056.13 KFH45013.1 - 0.2 10.7 19.2 0.94 8.5 0.9 3.2 3 0 0 3 3 3 0 Myc amino-terminal region Cwf_Cwc_15 PF04889.7 KFH45013.1 - 0.6 9.7 30.5 1.4 8.5 4.6 3.4 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.6 KFH45013.1 - 4.1 6.8 28.3 0.012 15.1 3.5 3.1 3 0 0 3 3 3 0 PPP4R2 Nucleoplasmin PF03066.10 KFH45013.1 - 5.8 6.4 37.1 1.8 8.0 5.5 3.4 3 0 0 3 3 3 0 Nucleoplasmin IU_nuc_hydro PF01156.14 KFH45014.1 - 7.6e-83 278.2 0.0 8.7e-83 278.1 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase MBOAT_2 PF13813.1 KFH45015.1 - 3.3e-14 52.7 6.5 8.6e-14 51.3 4.5 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Halogen_Hydrol PF10112.4 KFH45016.1 - 3.3 7.0 1.0 36 3.6 0.1 2.4 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein TMPIT PF07851.8 KFH45016.1 - 8.7 5.3 1.0 19 4.1 0.7 1.6 1 0 0 1 1 1 0 TMPIT-like protein DEAD PF00270.24 KFH45017.1 - 1.9e-44 151.1 0.0 2e-43 147.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFH45017.1 - 1.8e-24 85.3 0.0 6e-24 83.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AF1Q PF15017.1 KFH45018.1 - 0.88 9.5 6.3 0.38 10.7 1.8 2.2 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator TFIIA PF03153.8 KFH45018.1 - 2.9 7.7 17.1 3.9 7.2 11.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_2 PF07724.9 KFH45019.1 - 2.3e-44 151.2 0.2 4.1e-43 147.2 0.0 2.8 3 1 0 3 3 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 KFH45019.1 - 2.2e-24 85.1 0.2 2.2e-24 85.1 0.1 2.2 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 KFH45019.1 - 4.2e-19 69.0 0.0 1.3e-10 41.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFH45019.1 - 2.4e-13 50.0 0.2 4.5e-09 36.1 0.0 3.5 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KFH45019.1 - 2.8e-11 43.7 8.9 0.00053 20.0 0.0 5.0 3 3 2 5 5 5 3 AAA ATPase domain AAA_22 PF13401.1 KFH45019.1 - 1.4e-10 41.4 0.5 0.0004 20.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.21 KFH45019.1 - 3.3e-07 29.9 0.1 0.00032 20.2 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain Arch_ATPase PF01637.13 KFH45019.1 - 4.7e-06 26.4 8.1 0.035 13.7 0.2 4.8 3 2 0 3 3 3 1 Archaeal ATPase NACHT PF05729.7 KFH45019.1 - 5.2e-06 26.2 0.1 0.16 11.6 0.0 2.8 2 1 0 2 2 2 2 NACHT domain AAA_14 PF13173.1 KFH45019.1 - 5.6e-06 26.2 0.0 0.08 12.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KFH45019.1 - 6.9e-06 26.8 6.4 0.0062 17.3 0.0 4.1 4 1 0 4 4 3 1 AAA domain AAA_18 PF13238.1 KFH45019.1 - 7.2e-05 23.1 7.9 0.051 13.8 0.0 3.9 4 0 0 4 4 3 2 AAA domain AAA_19 PF13245.1 KFH45019.1 - 0.00014 21.4 0.0 0.054 13.2 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain IstB_IS21 PF01695.12 KFH45019.1 - 0.00016 21.1 0.0 0.29 10.5 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein MobB PF03205.9 KFH45019.1 - 0.00084 19.0 0.0 0.1 12.3 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KFH45019.1 - 0.003 17.8 0.9 0.97 9.7 0.0 3.4 3 0 0 3 3 3 1 ABC transporter RNA_helicase PF00910.17 KFH45019.1 - 0.0031 17.6 0.0 0.43 10.7 0.0 3.0 2 1 0 2 2 2 1 RNA helicase AAA_28 PF13521.1 KFH45019.1 - 0.0037 17.2 0.4 5.7 6.8 0.0 3.3 3 1 0 3 3 3 0 AAA domain IncA PF04156.9 KFH45019.1 - 0.0039 16.8 6.3 0.0039 16.8 4.3 1.8 2 0 0 2 2 1 1 IncA protein Mg_chelatase PF01078.16 KFH45019.1 - 0.0049 16.0 0.0 1.5 7.9 0.0 3.0 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KFH45019.1 - 0.0056 16.0 0.0 1.7 7.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain SRP54 PF00448.17 KFH45019.1 - 0.0058 16.0 0.0 0.21 11.0 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_15 PF13175.1 KFH45019.1 - 0.006 15.6 3.6 0.069 12.1 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 KFH45019.1 - 0.006 16.0 0.1 0.31 10.4 0.0 3.4 2 2 0 2 2 2 1 AAA-like domain DUF258 PF03193.11 KFH45019.1 - 0.0085 15.2 0.0 2.3 7.4 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 PhoH PF02562.11 KFH45019.1 - 0.013 14.7 0.1 0.46 9.6 0.0 2.6 3 0 0 3 3 2 0 PhoH-like protein TrwB_AAD_bind PF10412.4 KFH45019.1 - 0.016 13.8 0.0 3.2 6.2 0.0 2.6 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.10 KFH45019.1 - 0.023 14.5 4.2 8.1 6.2 0.0 3.8 3 1 0 4 4 4 0 Type III restriction enzyme, res subunit AAA_33 PF13671.1 KFH45019.1 - 0.027 14.3 0.0 4.3 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KFH45019.1 - 0.031 13.8 0.4 1.2 8.6 0.0 3.1 3 1 0 4 4 2 0 AAA domain UvrD-helicase PF00580.16 KFH45019.1 - 0.037 13.3 3.1 0.75 9.0 0.0 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_24 PF13479.1 KFH45019.1 - 0.039 13.5 0.0 0.94 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Mnd1 PF03962.10 KFH45019.1 - 0.05 13.2 12.8 0.1 12.2 8.9 1.5 1 0 0 1 1 1 0 Mnd1 family Cob_adeno_trans PF01923.13 KFH45019.1 - 0.058 13.1 4.2 9 6.0 3.4 3.0 2 1 0 2 2 2 0 Cobalamin adenosyltransferase APG6 PF04111.7 KFH45019.1 - 0.064 12.2 8.3 0.11 11.5 5.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 PduV-EutP PF10662.4 KFH45019.1 - 0.067 12.6 0.0 2.1 7.8 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 KFH45019.1 - 0.071 12.6 0.0 4.1 6.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Med2 PF11214.3 KFH45019.1 - 0.072 13.1 6.9 0.26 11.3 3.7 2.4 2 0 0 2 2 2 0 Mediator complex subunit 2 ATP_bind_1 PF03029.12 KFH45019.1 - 0.077 12.5 0.0 0.56 9.7 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Miro PF08477.8 KFH45019.1 - 0.077 13.4 0.0 2.7 8.5 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein UPF0079 PF02367.12 KFH45019.1 - 0.083 12.5 0.0 15 5.2 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 OEP PF02321.13 KFH45019.1 - 0.092 12.3 4.1 0.19 11.3 2.8 1.4 1 0 0 1 1 1 0 Outer membrane efflux protein DNA_topoisoIV PF00521.15 KFH45019.1 - 0.12 11.1 4.2 0.22 10.3 2.9 1.3 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Atg14 PF10186.4 KFH45019.1 - 0.13 11.2 9.2 0.26 10.2 6.4 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TcdA_TcdB PF12919.2 KFH45019.1 - 0.37 9.2 4.9 0.64 8.4 3.4 1.3 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Seryl_tRNA_N PF02403.17 KFH45019.1 - 0.62 10.1 15.0 1.5 8.8 9.0 2.9 2 1 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain V_ATPase_I PF01496.14 KFH45019.1 - 0.63 7.8 6.0 0.89 7.3 4.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.1 KFH45019.1 - 0.96 9.7 20.8 1.9e+02 2.2 0.0 3.4 2 1 0 2 2 2 0 AAA domain FlxA PF14282.1 KFH45019.1 - 1.3 9.0 9.7 3.9 7.4 0.5 2.4 1 1 1 2 2 2 0 FlxA-like protein GrpE PF01025.14 KFH45019.1 - 4.2 6.8 13.1 8.6 5.8 7.9 2.4 2 0 0 2 2 2 0 GrpE 2-oxoacid_dh PF00198.18 KFH45020.1 - 6.7e-78 261.1 0.0 9.1e-78 260.6 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KFH45020.1 - 5.2e-17 61.2 0.1 9.8e-17 60.3 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KFH45020.1 - 1.4e-10 40.6 0.1 3.2e-10 39.4 0.1 1.7 1 0 0 1 1 1 1 e3 binding domain DUF3597 PF12200.3 KFH45020.1 - 1.6 9.1 6.0 1.1 9.6 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) Ribosomal_60s PF00428.14 KFH45021.1 - 0.035 14.4 7.2 0.053 13.9 5.0 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Myc_N PF01056.13 KFH45021.1 - 0.12 11.4 1.0 0.12 11.4 0.7 1.1 1 0 0 1 1 1 0 Myc amino-terminal region DUF3682 PF12446.3 KFH45021.1 - 0.23 11.7 6.0 0.35 11.1 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Nucleoplasmin PF03066.10 KFH45021.1 - 0.51 9.8 6.1 0.51 9.8 4.2 1.1 1 0 0 1 1 1 0 Nucleoplasmin MFS_2 PF13347.1 KFH45022.1 - 2.6e-11 42.5 13.3 2.6e-11 42.5 9.2 2.4 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 KFH45022.1 - 0.013 15.2 0.9 0.25 11.1 0.0 3.1 2 0 0 2 2 2 0 MFS_1 like family Cep57_MT_bd PF06657.8 KFH45023.1 - 0.0035 17.2 0.0 0.0035 17.2 0.0 4.8 3 1 3 6 6 6 1 Centrosome microtubule-binding domain of Cep57 Filament PF00038.16 KFH45023.1 - 0.0036 16.8 20.1 0.0036 16.8 13.9 4.9 2 1 2 4 4 4 1 Intermediate filament protein Reo_sigmaC PF04582.7 KFH45023.1 - 0.0064 15.7 13.3 0.3 10.2 3.3 2.3 1 1 1 2 2 2 2 Reovirus sigma C capsid protein ATG16 PF08614.6 KFH45023.1 - 0.014 15.2 7.3 0.014 15.2 5.1 5.1 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) HOOK PF05622.7 KFH45023.1 - 0.072 10.8 51.7 0.04 11.7 20.0 3.3 3 0 0 3 3 3 0 HOOK protein CCDC92 PF14916.1 KFH45023.1 - 0.29 10.7 7.4 0.37 10.4 0.0 4.2 5 0 0 5 5 5 0 Coiled-coil domain of unknown function NPV_P10 PF05531.7 KFH45023.1 - 1.1 9.5 9.7 11 6.3 1.0 4.3 2 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 KFH45023.1 - 1.6 8.2 66.8 0.03 13.9 12.2 4.5 2 1 2 4 4 4 0 IncA protein DUF2408 PF10303.4 KFH45024.1 - 1.3e-42 145.0 3.5 2.8e-24 85.7 0.0 5.1 2 2 3 5 5 5 3 Protein of unknown function (DUF2408) Snapin_Pallidin PF14712.1 KFH45024.1 - 0.025 14.9 1.4 0.71 10.2 0.7 3.1 2 1 0 2 2 2 0 Snapin/Pallidin DUF4200 PF13863.1 KFH45024.1 - 0.027 14.4 0.3 0.1 12.5 0.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Spc7 PF08317.6 KFH45024.1 - 0.031 12.9 2.0 0.062 11.9 1.4 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3336 PF11815.3 KFH45024.1 - 0.037 13.5 0.7 0.081 12.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3336) DUF1539 PF07560.6 KFH45024.1 - 0.053 13.3 0.3 0.14 12.0 0.1 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) Ino80_Iec3 PF14612.1 KFH45025.1 - 8.7e-54 183.0 2.9 1.4e-33 116.9 0.3 2.1 1 1 1 2 2 2 2 IEC3 subunit of the Ino80 complex, chromatin re-modelling zf-CCCH PF00642.19 KFH45026.1 - 7.3e-05 22.3 2.9 0.00014 21.4 2.0 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KFH45026.1 - 1 9.4 3.4 1.7 8.7 2.3 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Pkinase PF00069.20 KFH45027.1 - 8.7e-64 215.1 0.0 1.5e-63 214.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH45027.1 - 1.2e-43 149.0 0.0 2.1e-43 148.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH45027.1 - 0.00033 19.7 0.0 0.0013 17.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Sugar_tr PF00083.19 KFH45028.1 - 1.2e-96 324.0 23.8 1.4e-96 323.8 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH45028.1 - 2.4e-24 85.6 28.9 6.7e-24 84.2 14.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily YrhK PF14145.1 KFH45028.1 - 0.28 10.8 7.3 0.37 10.4 0.1 3.5 3 0 0 3 3 3 0 YrhK-like protein Pro-kuma_activ PF09286.6 KFH45029.1 - 2.5e-17 63.2 0.0 6.3e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KFH45029.1 - 2e-11 43.5 0.1 3.3e-11 42.8 0.1 1.2 1 0 0 1 1 1 1 Subtilase family Abhydrolase_6 PF12697.2 KFH45030.1 - 3.8e-27 95.6 0.1 4.6e-27 95.3 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFH45030.1 - 7.3e-15 55.1 0.1 2.1e-12 47.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFH45030.1 - 7e-08 32.3 0.1 1.5e-07 31.3 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KFH45030.1 - 1.6e-07 31.0 0.0 4.5e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 Putative lysophospholipase Ndr PF03096.9 KFH45030.1 - 1.9e-06 26.6 0.0 2.2e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Ndr family BAAT_C PF08840.6 KFH45030.1 - 0.0038 16.9 0.0 0.42 10.2 0.0 2.2 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal zf-C2H2 PF00096.21 KFH45031.1 - 5.7e-05 23.2 14.3 0.095 13.0 1.6 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFH45031.1 - 0.00015 21.8 14.0 0.14 12.5 1.3 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger HAP1_N PF04849.8 KFH45031.1 - 0.0005 19.1 3.5 0.00073 18.5 2.4 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region bZIP_1 PF00170.16 KFH45031.1 - 0.019 14.8 0.5 0.039 13.8 0.4 1.5 1 0 0 1 1 1 0 bZIP transcription factor CCDC155 PF14662.1 KFH45031.1 - 0.021 14.4 1.7 0.033 13.7 1.2 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 Rab5-bind PF09311.6 KFH45031.1 - 0.022 14.6 3.7 0.043 13.7 2.6 1.4 1 0 0 1 1 1 0 Rabaptin-like protein Herpes_BLRF2 PF05812.7 KFH45031.1 - 0.031 14.0 1.2 0.082 12.7 0.8 1.7 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein TSC22 PF01166.13 KFH45031.1 - 0.042 13.8 0.9 0.094 12.6 0.6 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF3450 PF11932.3 KFH45031.1 - 0.046 12.9 0.9 0.065 12.4 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) APG6 PF04111.7 KFH45031.1 - 0.047 12.7 3.1 0.071 12.1 2.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 HALZ PF02183.13 KFH45031.1 - 0.082 12.6 3.0 0.09 12.5 0.8 1.9 1 1 1 2 2 2 0 Homeobox associated leucine zipper DivIC PF04977.10 KFH45031.1 - 0.1 12.0 3.4 0.22 11.0 2.2 1.7 1 1 0 1 1 1 0 Septum formation initiator K-box PF01486.12 KFH45031.1 - 0.1 12.3 2.6 7.2 6.4 0.2 2.4 1 1 1 2 2 2 0 K-box region zf-H2C2_2 PF13465.1 KFH45031.1 - 0.1 12.9 15.7 4.4 7.7 0.1 4.3 4 0 0 4 4 4 0 Zinc-finger double domain DUF904 PF06005.7 KFH45031.1 - 0.14 12.4 2.5 0.33 11.2 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF904) zf-RAG1 PF10426.4 KFH45031.1 - 0.25 11.3 0.2 0.25 11.3 0.1 3.2 4 0 0 4 4 4 0 Recombination-activating protein 1 zinc-finger domain bZIP_2 PF07716.10 KFH45031.1 - 0.26 11.1 3.9 0.28 11.0 1.1 2.2 1 1 1 2 2 2 0 Basic region leucine zipper HAUS6_N PF14661.1 KFH45031.1 - 0.26 10.5 1.8 0.52 9.6 1.2 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus GET2 PF08690.5 KFH45031.1 - 0.27 10.4 1.1 0.39 9.9 0.7 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 DUF972 PF06156.8 KFH45031.1 - 0.4 11.0 2.6 0.55 10.5 0.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 KFH45031.1 - 0.41 10.2 3.4 0.64 9.5 2.3 1.2 1 0 0 1 1 1 0 IncA protein OB_NTP_bind PF07717.11 KFH45032.1 - 5.5e-30 103.5 0.0 1.4e-29 102.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KFH45032.1 - 5e-23 81.0 0.1 5e-23 81.0 0.0 3.0 4 0 0 4 4 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KFH45032.1 - 3.4e-13 49.2 0.0 9.7e-13 47.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KFH45032.1 - 6.8e-06 26.2 0.0 2.6e-05 24.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 KFH45032.1 - 1.6e-05 24.4 0.0 4e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 KFH45032.1 - 0.00046 19.1 0.0 0.0011 17.9 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.17 KFH45032.1 - 0.0025 17.3 0.5 0.0092 15.4 0.0 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Trypan_PARP PF05887.6 KFH45032.1 - 0.03 14.1 11.8 0.078 12.7 8.2 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ABC_tran PF00005.22 KFH45032.1 - 0.067 13.4 0.1 0.25 11.6 0.0 2.1 2 0 0 2 2 1 0 ABC transporter cobW PF02492.14 KFH45032.1 - 0.084 12.3 0.2 0.84 9.0 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 KFH45032.1 - 0.095 12.6 1.3 0.66 9.8 0.1 2.8 2 1 0 2 2 2 0 AAA domain NACHT PF05729.7 KFH45032.1 - 0.12 12.0 1.9 2.2 7.9 0.1 3.4 3 1 0 3 3 3 0 NACHT domain Sugar_tr PF00083.19 KFH45033.1 - 1e-55 189.1 22.5 1.3e-55 188.8 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH45033.1 - 6.4e-19 67.8 36.5 6.6e-19 67.8 22.5 2.3 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 KFH45033.1 - 2.3e-07 29.6 6.5 2.3e-07 29.6 4.5 3.3 1 1 0 3 3 3 3 MFS/sugar transport protein DUF2207 PF09972.4 KFH45033.1 - 0.027 13.0 8.1 0.045 12.3 0.0 3.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Epimerase PF01370.16 KFH45034.1 - 0.036 13.5 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.13 KFH45036.1 - 6.1e-19 67.9 0.0 1.1e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH45036.1 - 0.069 13.0 1.3 0.14 12.0 0.9 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_transf_90 PF05686.7 KFH45037.1 - 5.1e-14 51.7 0.1 2e-10 39.9 0.0 3.4 3 0 0 3 3 3 3 Glycosyl transferase family 90 Reo_sigmaC PF04582.7 KFH45038.1 - 5.6e-05 22.4 7.0 9.2e-05 21.7 4.8 1.3 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Cast PF10174.4 KFH45038.1 - 7.5e-05 20.9 19.8 0.00014 20.0 13.7 1.4 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone IncA PF04156.9 KFH45038.1 - 0.00039 20.0 22.4 0.00039 20.0 15.5 2.5 2 1 1 3 3 3 1 IncA protein AAA_13 PF13166.1 KFH45038.1 - 0.00041 18.9 15.1 0.00041 18.9 10.5 1.6 2 0 0 2 2 2 1 AAA domain Macoilin PF09726.4 KFH45038.1 - 0.0011 17.3 12.7 0.0011 17.3 8.8 2.2 2 0 0 2 2 2 1 Transmembrane protein EzrA PF06160.7 KFH45038.1 - 0.049 11.8 19.9 0.0098 14.1 8.6 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA LMBR1 PF04791.11 KFH45038.1 - 0.071 11.6 3.4 0.1 11.1 2.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein FUSC PF04632.7 KFH45038.1 - 0.23 9.8 1.9 0.31 9.4 1.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-F_leu_zip PF10473.4 KFH45038.1 - 0.33 10.7 28.9 0.033 14.0 9.0 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.6 KFH45038.1 - 0.37 9.3 31.0 0.19 10.3 8.5 2.5 2 1 1 3 3 3 0 Spc7 kinetochore protein BRE1 PF08647.6 KFH45038.1 - 0.42 10.6 25.0 1.4 8.8 7.8 2.8 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Atg14 PF10186.4 KFH45038.1 - 0.6 8.9 23.2 0.058 12.3 11.7 2.3 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 BLOC1_2 PF10046.4 KFH45038.1 - 0.63 10.2 19.0 0.18 11.9 4.1 3.3 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ADIP PF11559.3 KFH45038.1 - 0.86 9.4 34.2 0.069 13.0 8.5 3.0 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.14 KFH45038.1 - 1.3 6.7 11.9 1.9 6.2 8.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Allexi_40kDa PF05549.6 KFH45038.1 - 1.4 8.1 11.1 4 6.6 6.6 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein Spectrin PF00435.16 KFH45038.1 - 2.2 8.5 22.7 9.6 6.5 4.3 3.3 1 1 2 3 3 3 0 Spectrin repeat GAS PF13851.1 KFH45038.1 - 2.2 7.4 27.7 13 4.8 19.3 2.1 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.5 KFH45038.1 - 3.7 7.6 16.8 3.4 7.7 6.7 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Syntaxin-6_N PF09177.6 KFH45038.1 - 4.2 7.8 11.1 2.7 8.4 5.2 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal GLE1 PF07817.8 KFH45038.1 - 4.5 6.1 13.5 5.1 5.9 0.8 2.2 2 0 0 2 2 2 0 GLE1-like protein MAD PF05557.8 KFH45038.1 - 4.6 5.2 34.1 0.29 9.1 19.4 2.0 2 1 1 3 3 3 0 Mitotic checkpoint protein USP8_interact PF08941.5 KFH45038.1 - 5.8 6.2 7.1 3.1 7.0 0.2 2.4 1 1 0 2 2 2 0 USP8 interacting Seryl_tRNA_N PF02403.17 KFH45038.1 - 5.8 6.9 30.4 0.11 12.5 9.5 3.1 3 1 1 4 4 2 0 Seryl-tRNA synthetase N-terminal domain ATG16 PF08614.6 KFH45038.1 - 6.2 6.5 38.5 0.21 11.3 9.9 3.3 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) Tox-SGS PF15651.1 KFH45039.1 - 0.048 13.4 0.0 0.061 13.0 0.0 1.1 1 0 0 1 1 1 0 Salivary glad secreted protein domain toxin p450 PF00067.17 KFH45040.1 - 2e-60 204.6 0.0 2.2e-60 204.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 YvrJ PF12841.2 KFH45040.1 - 0.41 9.9 3.5 1.5 8.1 0.1 3.3 4 0 0 4 4 4 0 YvrJ protein family UBX PF00789.15 KFH45042.1 - 0.00027 20.9 0.3 0.0007 19.6 0.0 1.9 2 0 0 2 2 2 1 UBX domain UBA PF00627.26 KFH45042.1 - 0.0005 19.8 0.0 0.0014 18.4 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain zf-C2H2_2 PF12756.2 KFH45042.1 - 0.019 15.0 1.6 0.022 14.8 0.4 1.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Evr1_Alr PF04777.8 KFH45042.1 - 0.68 9.8 3.5 0.29 11.0 0.3 2.0 2 0 0 2 2 2 0 Erv1 / Alr family CpXC PF14353.1 KFH45042.1 - 2 8.3 10.3 1.5 8.7 5.8 1.8 1 1 0 1 1 1 0 CpXC protein SOBP PF15279.1 KFH45042.1 - 7.3 6.8 10.1 9.2 6.5 7.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein RasGAP PF00616.14 KFH45043.1 - 1.5e-37 129.1 0.0 3e-37 128.1 0.0 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 KFH45043.1 - 0.0031 17.3 0.0 0.0082 15.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain Bac_luciferase PF00296.15 KFH45044.1 - 8.2e-61 205.7 1.1 1.1e-60 205.3 0.7 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase MRP-L20 PF12824.2 KFH45045.1 - 1.7e-46 158.1 4.7 2e-46 157.9 3.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.6 KFH45045.1 - 0.0013 18.5 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 Neugrin Unstab_antitox PF09720.5 KFH45045.1 - 0.037 13.7 0.3 0.078 12.6 0.2 1.5 1 0 0 1 1 1 0 Putative addiction module component HTH_11 PF08279.7 KFH45045.1 - 0.094 12.3 0.0 0.31 10.7 0.0 1.9 2 1 0 2 2 2 0 HTH domain Glyco_hydro_12 PF01670.11 KFH45046.1 - 4.1e-51 172.8 0.1 4.1e-51 172.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 12 JSRP PF15312.1 KFH45046.1 - 0.16 11.9 0.1 0.28 11.1 0.1 1.4 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein TraW_N PF12477.3 KFH45046.1 - 0.84 9.6 3.9 0.93 9.5 0.1 2.3 2 0 0 2 2 2 0 Sex factor F TraW protein N terminal FMN_dh PF01070.13 KFH45047.1 - 4.2e-124 413.9 0.0 4.9e-124 413.7 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 KFH45047.1 - 7.2e-05 22.0 3.1 0.00011 21.4 2.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KFH45047.1 - 0.00017 20.6 0.9 0.0033 16.3 0.4 2.1 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 KFH45047.1 - 0.00051 19.2 0.8 0.06 12.4 0.3 2.2 1 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 KFH45047.1 - 0.0033 16.4 0.3 0.0047 15.8 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IGPS PF00218.16 KFH45047.1 - 0.083 11.9 0.3 0.21 10.5 0.2 1.6 1 1 0 1 1 1 0 Indole-3-glycerol phosphate synthase Mur_ligase_M PF08245.7 KFH45048.1 - 0.00015 21.8 0.0 0.00046 20.2 0.0 1.8 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 KFH45048.1 - 0.014 15.3 0.0 0.032 14.2 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain RasGAP_C PF03836.10 KFH45048.1 - 0.048 13.3 0.2 1.2 8.8 0.1 2.3 1 1 1 2 2 2 0 RasGAP C-terminus DUF3508 PF12018.3 KFH45048.1 - 0.1 11.5 0.6 0.16 10.9 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3508) EzrA PF06160.7 KFH45048.1 - 0.19 9.8 0.6 0.28 9.2 0.4 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Abhydrolase_5 PF12695.2 KFH45050.1 - 5.7e-09 35.8 0.0 8.9e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFH45050.1 - 2.4e-08 34.1 0.3 3.7e-08 33.5 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFH45050.1 - 5.1e-06 25.8 0.0 6.8e-05 22.1 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KFH45050.1 - 0.0053 16.2 0.0 0.0074 15.7 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.13 KFH45050.1 - 0.044 13.0 0.0 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family Tyr_Deacylase PF02580.11 KFH45051.1 - 3.1e-47 160.1 0.1 3.6e-47 159.9 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase HypA PF01155.14 KFH45053.1 - 0.61 9.7 4.6 0.97 9.1 3.2 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-C2H2_4 PF13894.1 KFH45053.1 - 4.3 7.8 26.2 1.8 9.0 0.3 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KFH45054.1 - 2.6e-06 27.4 11.1 0.00034 20.7 1.5 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFH45054.1 - 5.8e-06 26.3 0.3 5.8e-06 26.3 0.2 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFH45054.1 - 0.0016 18.6 13.1 0.051 13.9 0.6 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFH45054.1 - 0.032 14.3 5.8 0.058 13.5 0.5 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFH45054.1 - 0.033 14.3 1.5 0.033 14.3 1.0 2.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 KFH45054.1 - 0.25 11.3 2.1 6.8 6.7 0.2 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-BED PF02892.10 KFH45054.1 - 1.7 8.4 6.1 10 6.0 0.4 2.4 1 1 0 2 2 2 0 BED zinc finger CRAL_TRIO PF00650.15 KFH45055.1 - 2.5e-39 134.3 0.0 4.4e-39 133.5 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KFH45055.1 - 2.4e-14 53.1 0.1 9.9e-14 51.2 0.1 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KFH45055.1 - 1.3e-09 38.1 0.0 2e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Pro_isomerase PF00160.16 KFH45056.1 - 6.3e-47 159.6 0.1 9e-47 159.1 0.1 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 KFH45056.1 - 5e-10 38.8 7.0 5.3e-06 25.9 0.2 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KFH45056.1 - 2.2e-08 33.4 2.9 0.0003 20.4 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFH45056.1 - 4.7e-05 23.9 6.0 0.0058 17.2 1.6 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFH45056.1 - 6e-05 22.4 0.9 0.027 14.0 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFH45056.1 - 0.0005 19.9 1.3 0.037 13.9 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFH45056.1 - 0.0046 16.7 0.2 0.011 15.5 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFH45056.1 - 0.041 14.5 7.2 0.7 10.6 1.3 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Iso_dh PF00180.15 KFH45057.1 - 7.5e-73 245.4 0.0 9e-73 245.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase OCIA PF07051.6 KFH45057.1 - 0.12 11.7 0.0 0.51 9.7 0.0 1.9 2 0 0 2 2 2 0 Ovarian carcinoma immunoreactive antigen (OCIA) MFS_1 PF07690.11 KFH45058.1 - 2e-31 109.0 34.4 3.3e-31 108.2 23.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH45058.1 - 0.0026 16.3 20.6 0.013 14.1 2.4 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter UNC-93 PF05978.11 KFH45058.1 - 0.32 10.4 8.1 0.02 14.4 1.8 1.8 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 Sec1 PF00995.18 KFH45059.1 - 4.6e-147 491.0 0.0 5.5e-147 490.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family FCH PF00611.18 KFH45060.1 - 1.7e-20 73.0 3.7 2.3e-20 72.5 0.0 2.9 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 KFH45060.1 - 6.2e-19 67.3 0.2 5.7e-11 41.8 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KFH45060.1 - 5.8e-16 57.6 0.1 2.3e-07 30.0 0.0 2.4 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.17 KFH45060.1 - 3e-14 52.4 5.3 4.7e-14 51.8 3.6 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_2 PF07653.12 KFH45060.1 - 4.3e-06 26.1 0.1 0.015 14.7 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.6 KFH45060.1 - 0.0028 17.7 0.2 1.4 9.1 0.0 2.7 2 0 0 2 2 2 2 Bacterial SH3 domain Allexi_40kDa PF05549.6 KFH45060.1 - 0.049 12.9 0.1 0.049 12.9 0.0 2.4 3 0 0 3 3 3 0 Allexivirus 40kDa protein Atg14 PF10186.4 KFH45060.1 - 0.27 10.1 9.0 0.33 9.8 0.2 2.5 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 C1_2 PF03107.11 KFH45060.1 - 0.57 10.3 7.8 0.96 9.6 5.4 1.3 1 0 0 1 1 1 0 C1 domain Not3 PF04065.10 KFH45061.1 - 2.8e-97 324.6 27.0 4.4e-97 323.9 18.7 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 KFH45061.1 - 2.3e-42 144.0 5.5 7.5e-42 142.3 3.8 1.9 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Snapin_Pallidin PF14712.1 KFH45061.1 - 0.0022 18.2 0.9 0.0022 18.2 0.6 2.7 2 0 0 2 2 2 1 Snapin/Pallidin DUF2373 PF10180.4 KFH45061.1 - 0.0087 15.5 3.1 0.019 14.5 2.1 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) DUF1192 PF06698.6 KFH45061.1 - 0.61 9.9 6.3 0.33 10.7 1.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) DUF904 PF06005.7 KFH45061.1 - 1.4 9.3 15.0 0.24 11.7 0.9 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Poty_PP PF08440.5 KFH45061.1 - 1.4 7.9 7.6 0.32 10.0 2.4 1.8 1 1 1 2 2 2 0 Potyviridae polyprotein DivIC PF04977.10 KFH45061.1 - 2.5 7.6 15.7 0.78 9.2 0.5 3.0 2 1 0 2 2 2 0 Septum formation initiator Translin PF01997.11 KFH45062.1 - 1.2e-44 152.3 0.0 1.3e-44 152.1 0.0 1.0 1 0 0 1 1 1 1 Translin family Ferritin PF00210.19 KFH45062.1 - 0.017 14.9 0.2 0.78 9.4 0.2 2.5 2 1 0 2 2 2 0 Ferritin-like domain GMP_synt_C PF00958.17 KFH45062.1 - 0.053 13.2 0.2 0.17 11.5 0.1 2.0 1 1 0 1 1 1 0 GMP synthase C terminal domain Prefoldin PF02996.12 KFH45062.1 - 0.17 11.5 0.8 0.46 10.1 0.2 2.0 2 0 0 2 2 2 0 Prefoldin subunit Pyr_redox_3 PF13738.1 KFH45063.1 - 7.3e-22 78.4 0.0 2.4e-21 76.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFH45063.1 - 1.5e-15 56.3 0.0 3.3e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KFH45063.1 - 2.1e-10 40.4 0.0 2.1e-09 37.2 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KFH45063.1 - 1.8e-07 30.3 0.0 6.9e-06 25.2 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KFH45063.1 - 0.00014 21.8 0.0 0.001 19.0 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFH45063.1 - 0.00079 19.2 0.3 0.74 9.5 0.0 3.1 2 2 1 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.19 KFH45063.1 - 0.0015 17.4 0.0 0.059 12.2 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFH45063.1 - 0.016 15.6 0.1 7.1 7.1 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFH45063.1 - 0.12 11.4 0.0 0.46 9.5 0.0 1.8 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 KFH45063.1 - 0.14 10.6 0.2 1.1 7.6 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein DUF1793 PF08760.6 KFH45064.1 - 1e-62 211.0 0.3 1.9e-62 210.1 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF3530 PF12048.3 KFH45065.1 - 0.11 11.4 1.7 0.11 11.4 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) MFS_1 PF07690.11 KFH45066.1 - 0.011 14.4 1.9 0.017 13.8 1.3 1.3 1 0 0 1 1 1 0 Major Facilitator Superfamily Sulfatase PF00884.18 KFH45067.1 - 4.2e-50 170.6 0.0 2.1e-48 165.0 0.0 2.4 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 KFH45067.1 - 1.2e-07 31.3 0.0 5.9e-06 25.8 0.0 2.4 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.7 KFH45067.1 - 0.00041 19.3 0.0 0.00069 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) Sulfatase_C PF14707.1 KFH45067.1 - 0.036 14.3 0.0 0.085 13.1 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF229 PF02995.12 KFH45067.1 - 0.037 12.4 0.0 0.048 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Motile_Sperm PF00635.21 KFH45068.1 - 1.9e-17 62.8 0.0 8.4e-17 60.7 0.0 2.0 1 1 1 2 2 2 1 MSP (Major sperm protein) domain I_LWEQ PF01608.12 KFH45068.1 - 0.39 10.6 3.1 0.59 10.0 2.2 1.2 1 0 0 1 1 1 0 I/LWEQ domain Cu-oxidase_3 PF07732.10 KFH45069.1 - 1.8e-41 140.5 0.2 1.8e-41 140.5 0.2 2.3 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KFH45069.1 - 2.5e-30 104.7 7.6 5.6e-26 90.6 0.2 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KFH45069.1 - 7.1e-13 48.7 0.0 6.3e-12 45.6 0.0 2.4 2 1 0 2 2 2 1 Multicopper oxidase YlbE PF14003.1 KFH45069.1 - 0.09 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 YlbE-like protein 7tm_2 PF00002.19 KFH45070.1 - 1.3e-07 30.9 10.5 1.3e-07 30.9 7.3 1.8 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 KFH45070.1 - 1.4e-07 30.7 2.8 3.2e-07 29.5 1.9 1.5 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor tRNA-synt_1b PF00579.20 KFH45071.1 - 1.4e-56 191.8 0.0 1.7e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF3470 PF11953.3 KFH45071.1 - 1.7 8.2 5.6 3.5 7.2 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3470) FAD_binding_6 PF00970.19 KFH45072.1 - 1.2e-07 31.7 0.0 2.1e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.17 KFH45072.1 - 1.1e-06 28.8 0.0 1.9e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.16 KFH45072.1 - 1.9e-05 25.1 0.0 3.2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KFH45072.1 - 0.01 15.7 0.0 0.42 10.5 0.0 2.8 3 0 0 3 3 3 0 Ferric reductase NAD binding domain Protoglobin PF11563.3 KFH45072.1 - 0.16 11.6 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Protoglobin DUF998 PF06197.8 KFH45073.1 - 0.064 12.5 5.7 0.13 11.6 4.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF998) Bac_Ubq_Cox PF01654.12 KFH45073.1 - 0.43 8.9 6.2 0.16 10.3 2.0 1.7 1 1 1 2 2 2 0 Bacterial Cytochrome Ubiquinol Oxidase HTH_OrfB_IS605 PF12323.3 KFH45073.1 - 1.4 8.3 3.9 0.29 10.4 0.3 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain zf-LITAF-like PF10601.4 KFH45074.1 - 4.9e-05 23.1 2.8 0.0011 18.8 1.9 2.1 1 1 0 1 1 1 1 LITAF-like zinc ribbon domain Zn_Tnp_IS1 PF03811.8 KFH45074.1 - 0.0039 16.6 5.6 0.015 14.7 0.2 2.6 3 0 0 3 3 3 1 InsA N-terminal domain zf-ISL3 PF14690.1 KFH45074.1 - 0.023 14.7 1.3 0.42 10.6 0.1 2.2 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Sgf11 PF08209.6 KFH45074.1 - 0.073 12.3 1.6 0.16 11.2 0.2 2.1 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Rubredoxin PF00301.15 KFH45074.1 - 0.078 12.8 1.6 7 6.6 0.1 2.5 2 0 0 2 2 2 0 Rubredoxin Terminase_GpA PF05876.7 KFH45074.1 - 0.084 11.2 1.0 0.1 10.8 0.7 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) GFA PF04828.9 KFH45074.1 - 0.35 10.8 2.0 3 7.8 1.4 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 KFH45074.1 - 0.6 9.3 2.9 6.4 6.1 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Ank_2 PF12796.2 KFH45075.1 - 4.4e-97 318.5 12.1 1.7e-16 60.3 0.1 10.8 2 2 7 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 KFH45075.1 - 3.8e-87 282.0 20.4 6e-09 35.2 0.2 17.2 17 0 0 17 17 17 14 Ankyrin repeat Ank_4 PF13637.1 KFH45075.1 - 2.1e-74 244.6 15.6 2.5e-08 34.2 0.0 14.0 7 4 9 16 16 16 14 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFH45075.1 - 2.4e-63 208.7 25.2 1.2e-08 34.9 0.1 13.0 5 4 7 13 13 13 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFH45075.1 - 3.2e-53 172.3 7.1 0.00023 21.1 0.1 17.7 19 0 0 19 19 19 10 Ankyrin repeat CorA PF01544.13 KFH45075.1 - 6.9e-11 41.7 3.0 1.7e-10 40.4 2.1 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Nitro_FeMo-Co PF02579.12 KFH45075.1 - 0.02 14.9 0.0 48 4.1 0.0 3.5 3 0 0 3 3 3 0 Dinitrogenase iron-molybdenum cofactor Calici_MSP PF05752.6 KFH45075.1 - 0.065 12.8 0.1 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Calicivirus minor structural protein FA_desaturase PF00487.19 KFH45076.1 - 2.7e-32 112.2 15.7 3.8e-32 111.7 10.9 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 KFH45076.1 - 4.3e-20 70.6 0.8 6.4e-20 70.1 0.1 1.7 2 0 0 2 2 2 1 Sphingolipid Delta4-desaturase (DES) Pkinase PF00069.20 KFH45077.1 - 1.1e-12 47.6 0.0 2.4e-05 23.6 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFH45077.1 - 1.1e-09 37.7 0.0 4.7e-06 25.8 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase DnaJ PF00226.26 KFH45078.1 - 3.2e-27 94.0 1.3 4.9e-27 93.4 0.9 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KFH45078.1 - 1.1e-16 60.6 16.0 1.7e-16 60.0 11.1 1.3 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 KFH45078.1 - 4.3e-12 45.7 0.0 4.6e-10 39.2 0.0 2.4 2 0 0 2 2 2 1 DnaJ C terminal domain HypA PF01155.14 KFH45078.1 - 0.012 15.2 4.9 0.59 9.8 0.1 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 KFH45078.1 - 0.12 12.2 7.7 1.5 8.6 0.8 2.3 2 0 0 2 2 2 0 Double zinc ribbon AMP-binding PF00501.23 KFH45079.1 - 8.5e-86 287.9 0.0 1e-85 287.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFH45079.1 - 6.6e-16 59.0 0.2 3.3e-15 56.7 0.1 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 KFH45079.1 - 0.0025 16.3 0.0 0.028 12.9 0.0 2.1 2 0 0 2 2 2 1 GH3 auxin-responsive promoter Ribosomal_60s PF00428.14 KFH45081.1 - 1.3e-24 86.3 7.4 1.6e-24 86.1 5.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein FYVE PF01363.16 KFH45082.1 - 0.0028 17.4 4.3 0.0028 17.4 3.0 2.6 3 1 0 3 3 3 1 FYVE zinc finger MacB_PCD PF12704.2 KFH45083.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 MacB-like periplasmic core domain Alpha_GJ PF03229.8 KFH45083.1 - 4.8 7.5 8.4 0.44 10.8 1.0 2.3 2 1 0 2 2 2 0 Alphavirus glycoprotein J DUF218 PF02698.12 KFH45084.1 - 7.2e-10 38.5 0.0 1.1e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain MFS_1 PF07690.11 KFH45085.1 - 5.3e-10 38.5 31.8 9.6e-10 37.6 21.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 KFH45085.1 - 2.2e-05 23.9 4.0 2.2e-05 23.9 2.8 2.5 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Glyco_hydro_43 PF04616.9 KFH45088.1 - 1.8e-45 155.2 4.9 2.3e-45 154.8 3.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_6 PF03422.10 KFH45088.1 - 4.7e-40 136.6 0.2 1e-39 135.5 0.2 1.6 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) DUF596 PF04591.7 KFH45088.1 - 0.053 13.4 0.1 0.86 9.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF596 Glyco_hydro_32N PF00251.15 KFH45088.1 - 0.23 10.7 4.4 0.8 8.9 3.1 1.8 1 1 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain ICE2 PF08426.5 KFH45089.1 - 1.3e-138 462.0 10.4 1.6e-138 461.8 7.2 1.0 1 0 0 1 1 1 1 ICE2 Fungal_trans_2 PF11951.3 KFH45090.1 - 1.2e-23 83.3 0.1 1.9e-23 82.7 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH45090.1 - 4.7e-06 26.3 8.1 6.9e-06 25.8 5.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CoA_transf_3 PF02515.12 KFH45091.1 - 2.5e-57 193.2 0.0 3.5e-57 192.7 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III YCII PF03795.9 KFH45094.1 - 3.5e-08 33.5 0.0 5.7e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain Cyclin PF08613.6 KFH45095.1 - 4.9e-37 127.6 0.1 1.1e-36 126.5 0.0 1.6 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 KFH45095.1 - 0.019 14.5 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain SR-25 PF10500.4 KFH45095.1 - 0.083 12.3 7.6 0.12 11.7 5.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NUDE_C PF04880.8 KFH45096.1 - 4.9e-21 75.8 6.1 4.9e-21 75.8 4.2 5.0 2 2 3 5 5 5 1 NUDE protein, C-terminal conserved region WEMBL PF05701.6 KFH45096.1 - 0.0051 15.3 31.0 0.0078 14.7 21.5 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Filament PF00038.16 KFH45096.1 - 0.36 10.2 33.7 1.6 8.0 9.9 2.7 2 1 1 3 3 3 0 Intermediate filament protein IncA PF04156.9 KFH45096.1 - 0.4 10.2 36.1 0.44 10.1 12.9 2.7 2 1 1 3 3 3 0 IncA protein CENP-F_leu_zip PF10473.4 KFH45096.1 - 0.68 9.7 36.5 2.5 7.9 7.0 3.6 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF745 PF05335.8 KFH45096.1 - 3.8 6.9 16.7 0.081 12.4 5.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Tho2 PF11262.3 KFH45096.1 - 4.1 6.3 14.0 0.8 8.6 3.4 2.2 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Tropomyosin_1 PF12718.2 KFH45096.1 - 4.9 6.9 36.9 20 5.0 5.9 3.8 2 1 1 3 3 3 0 Tropomyosin like AAA_13 PF13166.1 KFH45096.1 - 5.2 5.3 23.7 8 4.7 16.5 1.2 1 0 0 1 1 1 0 AAA domain DUF2353 PF09789.4 KFH45096.1 - 8.7 5.5 23.3 49 3.0 15.7 2.1 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) FAD_binding_4 PF01565.18 KFH45097.1 - 3.6e-31 107.4 0.5 6e-31 106.7 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFH45097.1 - 1.1e-12 47.5 0.0 2.2e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like AA_permease PF00324.16 KFH45099.1 - 3.7e-105 352.0 41.7 7.8e-105 350.9 28.9 1.5 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFH45099.1 - 2.1e-18 66.1 40.0 2.6e-18 65.7 27.7 1.1 1 0 0 1 1 1 1 Amino acid permease Aldo_ket_red PF00248.16 KFH45100.1 - 1.2e-64 217.8 0.0 1.4e-64 217.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AMP-binding PF00501.23 KFH45101.1 - 1.4e-61 208.2 0.0 2.6e-60 203.9 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 KFH45101.1 - 9e-10 39.3 0.4 2.8e-09 37.7 0.1 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ketoacyl-synt PF00109.21 KFH45102.1 - 8.7e-72 241.6 0.1 1.7e-71 240.7 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KFH45102.1 - 6.4e-62 208.4 0.1 2e-61 206.8 0.1 1.9 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 KFH45102.1 - 8.4e-51 173.1 0.0 1.7e-50 172.1 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KFH45102.1 - 2.9e-48 164.5 0.0 5.1e-48 163.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KFH45102.1 - 7.2e-48 162.6 0.0 2.3e-47 161.0 0.0 2.0 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KFH45102.1 - 7.8e-40 135.4 0.6 3e-39 133.5 0.4 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KFH45102.1 - 1.8e-19 69.5 0.0 7.4e-19 67.5 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KFH45102.1 - 3.4e-17 62.7 0.0 8.2e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KFH45102.1 - 1.1e-13 52.2 0.0 6.2e-13 49.7 0.0 2.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KFH45102.1 - 9.3e-11 41.7 0.0 2.2e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KFH45102.1 - 1.2e-09 38.2 0.1 1.4e-08 34.9 0.0 2.7 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.1 KFH45102.1 - 2.9e-09 36.6 0.0 7.3e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH45102.1 - 1.9e-08 34.8 0.0 7e-08 33.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH45102.1 - 5.6e-07 29.9 0.0 1.4e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFH45102.1 - 0.0014 17.7 0.0 0.003 16.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.12 KFH45102.1 - 0.021 14.2 0.0 0.049 13.0 0.0 1.6 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_16 PF10294.4 KFH45102.1 - 0.053 12.9 0.0 0.19 11.1 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase ACC_central PF08326.7 KFH45103.1 - 1.2e-251 836.8 0.0 1.8e-251 836.2 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 KFH45103.1 - 3.9e-175 582.9 0.0 5.4e-175 582.4 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 KFH45103.1 - 3.8e-52 176.6 0.0 7e-52 175.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KFH45103.1 - 7.8e-24 83.9 0.1 1.6e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KFH45103.1 - 6.4e-23 80.7 0.0 1.1e-19 70.3 0.0 3.6 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 KFH45103.1 - 5.2e-15 54.8 0.1 1.2e-14 53.6 0.1 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 KFH45103.1 - 8.1e-11 41.9 0.0 2.1e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KFH45103.1 - 0.0029 16.9 0.0 0.0069 15.7 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 KFH45103.1 - 0.011 15.5 0.0 0.034 14.0 0.0 1.8 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp PF02222.17 KFH45103.1 - 0.055 12.8 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 KFH45103.1 - 0.068 12.8 0.0 0.23 11.1 0.0 1.8 1 0 0 1 1 1 0 Biotin-lipoyl like Fiji_64_capsid PF05880.6 KFH45103.1 - 0.12 10.7 0.2 0.18 10.0 0.1 1.2 1 0 0 1 1 1 0 Fijivirus 64 kDa capsid protein ABC_tran PF00005.22 KFH45104.1 - 1.1e-42 145.5 0.0 7.2e-28 97.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KFH45104.1 - 5.8e-23 81.6 4.9 4e-14 52.7 1.9 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 KFH45104.1 - 8.6e-13 48.0 0.1 0.00028 20.1 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KFH45104.1 - 1.2e-06 27.9 0.6 0.0033 16.9 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 KFH45104.1 - 1.3e-06 28.6 0.1 0.076 12.9 0.0 4.1 2 2 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KFH45104.1 - 4e-06 26.9 0.2 0.011 15.6 0.1 3.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 KFH45104.1 - 1.4e-05 25.4 0.1 0.21 11.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 KFH45104.1 - 3.9e-05 23.4 0.0 0.52 10.2 0.0 2.9 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 KFH45104.1 - 0.0004 20.0 0.2 0.69 9.7 0.0 3.3 2 0 0 2 2 2 1 Part of AAA domain MMR_HSR1 PF01926.18 KFH45104.1 - 0.00049 20.0 0.0 0.014 15.3 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 KFH45104.1 - 0.00064 19.2 0.0 0.11 11.9 0.0 2.5 2 0 0 2 2 2 1 AAA-like domain DUF258 PF03193.11 KFH45104.1 - 0.00073 18.7 0.0 0.22 10.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KFH45104.1 - 0.0017 18.5 0.3 0.88 9.7 0.3 3.0 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KFH45104.1 - 0.0018 17.7 0.0 0.82 9.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KFH45104.1 - 0.003 17.0 0.8 0.029 13.8 0.0 2.5 2 1 0 2 2 2 1 FtsK/SpoIIIE family Dynamin_N PF00350.18 KFH45104.1 - 0.003 17.4 0.5 0.074 12.8 0.1 2.3 2 0 0 2 2 2 1 Dynamin family T2SE PF00437.15 KFH45104.1 - 0.0031 16.4 0.5 0.76 8.6 0.4 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF87 PF01935.12 KFH45104.1 - 0.006 16.4 0.5 0.012 15.4 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_17 PF13207.1 KFH45104.1 - 0.012 16.3 0.0 0.26 12.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 KFH45104.1 - 0.018 14.5 0.0 0.76 9.2 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase cobW PF02492.14 KFH45104.1 - 0.029 13.8 0.0 2.2 7.6 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 KFH45104.1 - 0.03 13.9 0.8 21 4.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 KFH45104.1 - 0.07 13.4 0.4 1.5 9.1 0.1 2.8 3 0 0 3 3 2 0 AAA domain Miro PF08477.8 KFH45104.1 - 0.087 13.3 0.0 23 5.4 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein DUF2075 PF09848.4 KFH45104.1 - 0.17 10.7 0.0 12 4.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AIG1 PF04548.11 KFH45104.1 - 0.2 10.7 0.7 1.2 8.1 0.3 2.4 3 0 0 3 3 3 0 AIG1 family Arch_ATPase PF01637.13 KFH45104.1 - 0.27 10.9 0.0 5.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase NACHT PF05729.7 KFH45104.1 - 0.33 10.5 1.5 12 5.5 0.1 2.8 3 0 0 3 3 2 0 NACHT domain Aminotran_3 PF00202.16 KFH45105.1 - 1.9e-80 270.2 0.5 2.3e-80 269.9 0.4 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Glyco_hydro_43 PF04616.9 KFH45106.1 - 1.9e-56 191.3 11.7 8.7e-50 169.4 4.2 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 KFH45106.1 - 9.1e-07 28.5 1.1 0.0037 16.6 0.0 2.7 2 1 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Pyr_redox_3 PF13738.1 KFH45108.1 - 2.7e-19 70.0 0.1 8.7e-19 68.3 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFH45108.1 - 1.4e-12 46.6 0.0 7e-06 24.5 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KFH45108.1 - 4e-11 43.1 0.0 1.5e-07 31.4 0.2 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFH45108.1 - 2.9e-08 33.5 1.3 1.6e-07 31.1 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFH45108.1 - 1.3e-07 30.8 0.5 2.8e-07 29.7 0.0 1.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFH45108.1 - 6.6e-07 29.6 3.5 0.028 14.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFH45108.1 - 2.8e-06 26.5 0.0 0.00042 19.3 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 KFH45108.1 - 0.00017 21.6 0.4 0.42 10.6 0.0 2.6 3 0 0 3 3 2 2 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 KFH45108.1 - 0.0012 18.5 0.1 0.002 17.8 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 KFH45108.1 - 0.0012 18.5 2.7 0.0081 15.9 0.1 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 KFH45108.1 - 0.0041 16.7 0.7 0.66 9.5 0.1 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 KFH45108.1 - 0.026 13.6 0.1 3.5 6.7 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 KFH45108.1 - 0.028 13.2 0.9 0.056 12.2 0.7 1.5 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KFH45108.1 - 0.12 10.7 3.2 0.082 11.3 0.3 1.8 2 0 0 2 2 2 0 HI0933-like protein Amino_oxidase PF01593.19 KFH45108.1 - 0.13 11.2 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 KFH45108.1 - 0.15 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 KFH45108.1 - 0.16 11.6 0.5 0.29 10.8 0.0 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.17 KFH45108.1 - 0.22 10.3 1.0 0.27 10.0 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.9 KFH45108.1 - 0.48 9.7 2.0 0.41 9.9 0.1 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain G-alpha PF00503.15 KFH45109.1 - 1.2e-21 76.8 0.0 1.5e-20 73.2 0.0 2.0 1 1 0 1 1 1 1 G-protein alpha subunit PAZ_siRNAbind PF12212.3 KFH45109.1 - 0.15 11.6 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Piwi/Argonaute/Zwille siRNA-binding domain RINGv PF12906.2 KFH45111.1 - 2.1e-15 56.4 8.4 3.4e-15 55.7 5.8 1.4 1 0 0 1 1 1 1 RING-variant domain Baculo_11_kDa PF06143.6 KFH45111.1 - 0.0048 16.2 3.7 0.078 12.3 1.3 2.6 2 0 0 2 2 2 1 Baculovirus 11 kDa family zf-Apc11 PF12861.2 KFH45111.1 - 0.086 12.6 3.0 0.21 11.4 2.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KFH45111.1 - 0.43 10.4 8.4 0.76 9.6 5.8 1.4 1 0 0 1 1 1 0 Ring finger domain TRI12 PF06609.8 KFH45113.1 - 2.7e-53 181.1 21.5 3.2e-53 180.8 14.9 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KFH45113.1 - 1.9e-20 72.8 47.6 1.9e-20 72.8 33.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH45113.1 - 1.3e-09 37.1 3.2 1.3e-09 37.1 2.2 3.1 3 1 0 3 3 3 2 Sugar (and other) transporter GMC_oxred_N PF00732.14 KFH45115.1 - 4.7e-45 154.0 0.0 8.9e-44 149.8 0.0 2.1 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFH45115.1 - 2.7e-34 118.5 0.0 4.9e-34 117.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KFH45115.1 - 2.1e-05 23.5 0.1 3.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFH45115.1 - 8.8e-05 22.4 0.4 0.00042 20.2 0.4 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KFH45115.1 - 0.00068 18.5 0.2 0.027 13.3 0.1 2.6 3 0 0 3 3 3 1 FAD binding domain GDI PF00996.13 KFH45115.1 - 0.0032 15.8 0.0 0.0048 15.2 0.0 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor FAD_binding_3 PF01494.14 KFH45115.1 - 0.042 12.8 0.2 0.066 12.2 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 KFH45115.1 - 0.17 10.7 0.4 0.32 9.8 0.3 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein BolA PF01722.13 KFH45116.1 - 4.7e-13 48.8 0.0 6.5e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein p450 PF00067.17 KFH45117.1 - 1.2e-17 63.5 1.8 1.2e-11 43.8 0.0 2.5 1 1 1 2 2 2 2 Cytochrome P450 adh_short PF00106.20 KFH45119.1 - 2.2e-13 50.4 0.0 2.5e-08 34.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KFH45119.1 - 7e-08 32.5 0.1 2.5e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 KFH45119.1 - 0.0001 21.1 0.0 0.00014 20.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KFH45119.1 - 0.00026 20.5 0.1 0.00048 19.6 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KFH45119.1 - 0.011 15.3 1.0 0.026 14.1 0.1 2.0 2 1 0 2 2 2 0 KR domain DOMON PF03351.12 KFH45120.1 - 0.061 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 DOMON domain TPP_enzyme_N PF02776.13 KFH45121.1 - 4.4e-39 133.7 0.1 7.3e-38 129.7 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KFH45121.1 - 1e-21 77.1 0.0 2.3e-21 75.9 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KFH45121.1 - 3.8e-19 68.8 0.0 1.8e-18 66.6 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain NTP_transf_3 PF12804.2 KFH45121.1 - 0.0079 16.2 0.6 0.32 11.0 0.2 3.2 2 1 0 2 2 2 1 MobA-like NTP transferase domain Ank_2 PF12796.2 KFH45122.1 - 1.2e-37 128.0 0.0 4.8e-18 65.2 0.0 3.1 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFH45122.1 - 7e-37 123.4 0.9 3.1e-09 36.1 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat zf-DHHC PF01529.15 KFH45122.1 - 1.7e-33 115.4 14.4 1.7e-33 115.4 10.0 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_4 PF13637.1 KFH45122.1 - 1.7e-26 92.1 4.5 2.3e-08 34.3 0.1 4.9 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFH45122.1 - 1.8e-26 91.5 1.0 8.7e-07 28.9 0.0 4.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFH45122.1 - 2.2e-24 83.0 1.0 3e-08 33.1 0.0 6.2 7 0 0 7 7 7 4 Ankyrin repeat AMP-binding PF00501.23 KFH45123.1 - 0 1579.1 3.5 5.6e-84 281.9 0.1 6.2 6 0 0 6 6 6 6 AMP-binding enzyme Condensation PF00668.15 KFH45123.1 - 1.5e-252 835.0 0.0 3e-44 151.0 0.0 8.5 8 0 0 8 8 8 8 Condensation domain PP-binding PF00550.20 KFH45123.1 - 2.2e-78 258.4 3.4 1.5e-12 47.6 0.0 7.0 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KFH45123.1 - 4.7e-39 133.1 19.6 0.00017 22.4 0.1 9.2 8 0 0 8 8 8 8 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 KFH45123.1 - 7.8e-15 54.9 0.1 3.1e-05 24.1 0.1 6.4 6 0 0 6 6 6 3 HxxPF-repeated domain Methyltransf_31 PF13847.1 KFH45123.1 - 3.6e-14 52.6 0.0 1.2e-06 28.1 0.0 2.9 3 0 0 3 3 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 KFH45123.1 - 8.6e-14 51.7 0.0 3e-05 24.2 0.0 3.9 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_18 PF12847.2 KFH45123.1 - 3.5e-12 46.8 0.0 0.00018 22.0 0.0 3.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 KFH45123.1 - 8e-11 42.0 0.0 0.00037 20.5 0.0 4.2 3 1 0 3 3 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 KFH45123.1 - 3.6e-08 33.7 0.0 0.01 16.3 0.0 3.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 KFH45123.1 - 5.2e-08 32.7 0.0 0.013 15.2 0.0 3.6 3 0 0 3 3 3 2 Methyltransferase domain MTS PF05175.9 KFH45123.1 - 0.00058 19.2 0.1 0.3 10.4 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_9 PF08003.6 KFH45123.1 - 0.0033 16.1 0.0 2.1 6.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1698) AATase PF07247.7 KFH45123.1 - 0.0039 15.8 0.6 0.65 8.4 0.0 2.9 3 0 0 3 3 3 1 Alcohol acetyltransferase Csm1 PF12539.3 KFH45123.1 - 0.025 15.0 1.1 59 4.2 0.0 5.0 6 0 0 6 6 6 0 Chromosome segregation protein Csm1/Pcs1 Methyltransf_16 PF10294.4 KFH45123.1 - 0.085 12.3 0.0 14 5.0 0.0 2.4 2 0 0 2 2 2 0 Putative methyltransferase GH3 PF03321.8 KFH45123.1 - 0.21 10.0 2.9 1.8 6.9 0.0 3.9 6 0 0 6 6 6 0 GH3 auxin-responsive promoter PrmA PF06325.8 KFH45123.1 - 0.49 9.4 0.0 23 3.9 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) MHYT PF03707.11 KFH45124.1 - 3.6e-07 30.2 23.8 2.3e-05 24.4 0.7 3.9 4 0 0 4 4 4 2 Bacterial signalling protein N terminal repeat DUF4328 PF14219.1 KFH45124.1 - 0.023 13.9 0.1 0.023 13.9 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4328) Peptidase_U4 PF03419.8 KFH45124.1 - 3.2 6.7 6.2 3.2 6.7 3.3 1.7 1 1 0 1 1 1 0 Sporulation factor SpoIIGA p450 PF00067.17 KFH45125.1 - 2e-24 85.9 0.0 4e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 ABM PF03992.11 KFH45126.1 - 3.8e-05 23.6 0.0 0.007 16.3 0.0 2.2 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase SRPRB PF09439.5 KFH45127.1 - 1.1e-27 96.4 0.0 2e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 KFH45127.1 - 9.6e-07 28.2 0.0 1.1e-05 24.7 0.0 2.3 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFH45127.1 - 4.7e-06 26.5 0.0 7e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFH45127.1 - 3.9e-05 23.1 0.2 9.4e-05 21.9 0.2 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 KFH45127.1 - 0.0013 18.7 0.2 0.003 17.5 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain Gtr1_RagA PF04670.7 KFH45127.1 - 0.0043 16.2 0.0 0.0094 15.1 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KFH45127.1 - 0.0061 17.0 0.0 0.036 14.5 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Septin PF00735.13 KFH45127.1 - 0.0075 15.3 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Septin cobW PF02492.14 KFH45127.1 - 0.0081 15.6 0.3 3.1 7.1 0.0 2.2 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 KFH45127.1 - 0.031 14.5 0.0 0.049 13.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Ras PF00071.17 KFH45127.1 - 0.052 12.9 0.0 0.17 11.2 0.0 1.9 1 1 0 1 1 1 0 Ras family SRP54 PF00448.17 KFH45127.1 - 0.07 12.5 0.6 6.1 6.2 0.1 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.1 KFH45127.1 - 0.07 12.6 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KFH45127.1 - 0.089 11.9 0.2 0.17 11.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 KFH45127.1 - 0.12 11.4 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.1 KFH45127.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 KFH45127.1 - 0.13 11.7 0.0 0.68 9.4 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Amidohydro_2 PF04909.9 KFH45128.1 - 6.2e-20 71.8 3.2 8.9e-20 71.3 2.2 1.3 1 1 0 1 1 1 1 Amidohydrolase AMP-binding PF00501.23 KFH45129.1 - 9.6e-251 831.2 0.2 2.8e-89 299.4 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 KFH45129.1 - 2.3e-147 489.6 0.0 5e-45 153.6 0.0 5.7 5 1 0 5 5 5 5 Condensation domain PP-binding PF00550.20 KFH45129.1 - 3.1e-36 123.4 2.1 4.1e-11 42.9 0.0 5.7 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KFH45129.1 - 1.4e-20 73.9 0.0 1.1e-05 26.2 0.0 3.8 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain HTH_Tnp_1 PF01527.15 KFH45129.1 - 0.0094 15.8 0.4 8.8 6.3 0.0 3.0 3 0 0 3 3 3 2 Transposase HxxPF_rpt PF13745.1 KFH45129.1 - 0.021 15.1 0.0 1.3 9.3 0.0 3.5 4 0 0 4 4 4 0 HxxPF-repeated domain AATase PF07247.7 KFH45129.1 - 0.022 13.3 0.0 1.5 7.3 0.0 3.3 4 0 0 4 4 4 0 Alcohol acetyltransferase GH3 PF03321.8 KFH45129.1 - 2.3 6.6 0.1 32 2.8 0.0 2.3 2 0 0 2 2 2 0 GH3 auxin-responsive promoter Herpes_gE PF02480.11 KFH45130.1 - 0.0056 14.9 0.0 0.0073 14.6 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 KFH45130.1 - 0.049 14.0 0.0 0.079 13.3 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LRR19-TM PF15176.1 KFH45130.1 - 0.051 13.2 0.1 0.065 12.9 0.1 1.3 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Mid2 PF04478.7 KFH45130.1 - 0.13 11.6 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Shisa PF13908.1 KFH45130.1 - 0.14 12.3 0.1 0.19 11.8 0.1 1.4 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Rick_17kDa_Anti PF05433.10 KFH45130.1 - 0.24 11.0 1.5 0.42 10.3 1.0 1.3 1 0 0 1 1 1 0 Glycine zipper 2TM domain Dabb PF07876.7 KFH45131.1 - 1.3e-08 35.2 0.0 1.4e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain PALP PF00291.20 KFH45133.1 - 8.4e-59 199.2 0.4 2.4e-58 197.8 0.1 1.7 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 KFH45133.1 - 2.1e-11 43.4 0.0 3.5e-08 33.1 0.0 2.7 2 0 0 2 2 2 2 CBS domain Pribosyltran PF00156.22 KFH45133.1 - 0.097 12.4 0.4 5.5 6.7 0.0 2.5 2 0 0 2 2 2 0 Phosphoribosyl transferase domain Peptidase_M28 PF04389.12 KFH45134.1 - 3.3e-38 131.2 0.1 5.3e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KFH45134.1 - 1.3e-12 47.2 0.1 3e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 KFH45134.1 - 0.00017 21.1 0.0 0.0003 20.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF2172 PF09940.4 KFH45134.1 - 0.0029 16.0 0.0 0.0046 15.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2172) YebO PF13974.1 KFH45136.1 - 0.12 12.1 0.6 0.42 10.4 0.0 1.9 2 0 0 2 2 2 0 YebO-like protein p450 PF00067.17 KFH45139.1 - 2.9e-26 92.0 0.6 4e-26 91.5 0.4 1.2 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_24 PF13578.1 KFH45139.1 - 0.035 14.9 0.7 2.7 8.8 0.1 3.1 3 0 0 3 3 3 0 Methyltransferase domain EAP30 PF04157.11 KFH45140.1 - 5.7e-55 185.9 0.0 7.5e-55 185.5 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 KFH45140.1 - 1.2e-26 92.2 0.0 2e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.13 KFH45140.1 - 0.0003 19.8 1.0 0.0003 19.8 0.7 2.7 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others GRAM PF02893.15 KFH45140.1 - 0.0013 18.1 0.0 0.0028 17.1 0.0 1.4 1 0 0 1 1 1 1 GRAM domain zf-Sec23_Sec24 PF04810.10 KFH45140.1 - 0.0073 15.8 6.3 0.012 15.1 0.2 2.5 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger DZR PF12773.2 KFH45140.1 - 0.71 9.7 6.7 0.079 12.7 0.4 2.2 2 1 0 2 2 2 0 Double zinc ribbon IBN_N PF03810.14 KFH45141.1 - 1.4e-14 53.7 1.7 8.3e-14 51.2 0.1 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KFH45141.1 - 0.0034 17.2 0.0 0.026 14.4 0.0 2.6 2 1 0 2 2 2 1 Exportin 1-like protein Methyltransf_11 PF08241.7 KFH45142.1 - 3.5e-16 59.4 0.1 6.3e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH45142.1 - 1.5e-14 54.5 0.2 3.2e-14 53.4 0.1 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH45142.1 - 1.5e-10 41.0 0.0 1.8e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH45142.1 - 3e-10 39.9 0.0 5.1e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH45142.1 - 3.4e-09 37.0 0.1 6.2e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFH45142.1 - 2.6e-08 34.1 0.0 6.4e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFH45142.1 - 7.5e-07 29.1 0.4 2.1e-06 27.7 0.3 1.9 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFH45142.1 - 7.8e-07 28.4 0.2 1e-06 28.0 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 KFH45142.1 - 1.2e-06 27.8 0.0 1.5e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ADH_zinc_N PF00107.21 KFH45142.1 - 6.5e-05 22.4 0.9 0.00037 20.0 0.4 2.3 2 1 0 2 2 2 1 Zinc-binding dehydrogenase MTS PF05175.9 KFH45142.1 - 0.00012 21.4 0.1 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 KFH45142.1 - 0.00046 19.6 0.0 0.00065 19.1 0.0 1.1 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.14 KFH45142.1 - 0.0028 17.2 0.1 0.0033 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TPMT PF05724.6 KFH45142.1 - 0.0083 15.5 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.15 KFH45142.1 - 0.038 13.0 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.4 KFH45142.1 - 0.052 12.9 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase AdoMet_MTase PF07757.8 KFH45142.1 - 0.062 13.4 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase HAD PF12710.2 KFH45143.1 - 1.3e-12 48.3 0.1 1.7e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 KFH45143.1 - 0.00027 20.3 0.0 0.00065 19.0 0.0 1.6 1 1 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.1 KFH45143.1 - 0.0004 20.6 0.0 0.001 19.3 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 KFH45143.1 - 0.013 14.6 0.1 0.25 10.4 0.0 2.1 2 0 0 2 2 2 0 Putative Phosphatase Hydrolase PF00702.21 KFH45143.1 - 0.021 15.2 0.1 0.2 12.0 0.0 2.3 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF2611 PF11022.3 KFH45144.1 - 1.4e-26 92.3 0.0 1.5e-26 92.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) eIF-1a PF01176.14 KFH45145.1 - 9e-13 47.4 0.0 1.4e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 MFS_1 PF07690.11 KFH45146.1 - 1.2e-42 145.8 43.5 1e-38 132.9 29.6 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH45146.1 - 1.7e-16 59.8 7.6 1.7e-16 59.8 5.3 3.7 3 1 1 4 4 4 2 Sugar (and other) transporter TRI12 PF06609.8 KFH45146.1 - 2.7e-15 55.6 25.8 3.8e-15 55.1 17.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 KFH45146.1 - 4.5e-09 35.2 26.3 8.6e-08 30.9 0.8 3.5 2 1 1 3 3 3 3 MFS/sugar transport protein DUF1228 PF06779.9 KFH45146.1 - 0.0082 16.1 1.4 0.26 11.3 0.7 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1228) DUF3357 PF11837.3 KFH45146.1 - 0.26 11.1 0.6 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) DAO PF01266.19 KFH45148.1 - 5.8e-29 101.0 2.9 2e-28 99.3 2.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFH45148.1 - 0.0012 17.7 0.0 0.0018 17.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KFH45148.1 - 0.0023 17.9 1.2 0.0037 17.2 0.2 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KFH45148.1 - 0.019 14.0 0.4 0.019 14.0 0.3 1.8 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.14 KFH45148.1 - 0.05 12.6 0.7 0.11 11.5 0.5 1.5 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 KFH45148.1 - 0.067 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFH45148.1 - 0.075 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFH45148.1 - 0.09 13.1 0.2 0.24 11.7 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KFH45148.1 - 0.22 10.3 0.5 0.33 9.7 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Glyco_hydro_31 PF01055.21 KFH45150.1 - 2.1e-88 297.0 6.6 3.3e-88 296.4 4.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DEC-1_N PF04625.8 KFH45151.1 - 0.0029 16.3 1.3 0.0038 15.9 0.9 1.1 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region CBFB_NFYA PF02045.10 KFH45151.1 - 0.98 10.0 6.2 0.34 11.4 1.7 2.1 2 0 0 2 2 2 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Sas10_Utp3 PF04000.10 KFH45152.1 - 2.7e-17 62.7 1.3 5.5e-17 61.7 0.9 1.5 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Herpes_LMP2 PF07415.6 KFH45152.1 - 9.8 4.6 6.6 14 4.1 4.6 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein DUF2036 PF09724.4 KFH45154.1 - 6e-08 32.1 0.0 6.6e-08 32.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) DUF4147 PF13660.1 KFH45154.1 - 0.1 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) PAT1 PF09770.4 KFH45155.1 - 0.012 13.9 30.0 0.013 13.8 20.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SR-25 PF10500.4 KFH45155.1 - 0.028 13.8 14.4 0.043 13.2 10.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BLVR PF06375.6 KFH45155.1 - 2.7 7.8 12.0 4.6 7.0 8.3 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Cupin_7 PF12973.2 KFH45156.1 - 0.073 12.9 0.0 0.18 11.6 0.0 1.7 1 1 0 1 1 1 0 ChrR Cupin-like domain RhoGEF PF00621.15 KFH45157.1 - 1.2e-26 93.7 0.1 2.8e-26 92.5 0.0 1.7 2 0 0 2 2 2 1 RhoGEF domain DUF3507 PF12015.3 KFH45157.1 - 0.00034 20.1 0.0 0.00071 19.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) Reo_sigmaC PF04582.7 KFH45157.1 - 0.16 11.1 2.6 0.22 10.6 0.1 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Syntaxin_2 PF14523.1 KFH45157.1 - 1.9 8.5 9.8 12 5.9 0.5 3.8 2 1 2 4 4 4 0 Syntaxin-like protein RTA1 PF04479.8 KFH45159.1 - 2.9e-38 131.5 0.2 4.1e-38 131.1 0.1 1.1 1 0 0 1 1 1 1 RTA1 like protein MnhB PF04039.8 KFH45159.1 - 0.01 15.8 2.4 0.01 15.8 1.7 2.4 3 1 0 3 3 3 0 Domain related to MnhB subunit of Na+/H+ antiporter DUF218 PF02698.12 KFH45160.1 - 2.1e-20 72.7 0.0 5.8e-18 64.8 0.0 2.1 1 1 0 1 1 1 1 DUF218 domain Sin_N PF04801.8 KFH45161.1 - 2e-20 73.0 0.0 1e-19 70.7 0.0 1.9 1 1 0 1 1 1 1 Sin-like protein conserved region Fungal_trans_2 PF11951.3 KFH45162.1 - 1.2e-30 106.4 0.1 1.6e-30 105.9 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH45162.1 - 8.2e-06 25.6 9.2 1.3e-05 24.9 6.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 KFH45162.1 - 3.3 7.9 9.0 5.3 7.2 6.3 1.3 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Rho_GDI PF02115.12 KFH45163.1 - 4.5e-59 199.2 0.3 5e-59 199.0 0.2 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor NAD_binding_2 PF03446.10 KFH45165.1 - 4.3e-39 133.9 0.0 6.5e-39 133.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KFH45165.1 - 2.4e-31 108.3 0.1 4.6e-31 107.4 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 KFH45165.1 - 2.3e-07 31.1 0.0 9.2e-07 29.2 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Ldh_1_N PF00056.18 KFH45165.1 - 0.00017 21.4 0.0 0.00046 20.0 0.0 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.10 KFH45165.1 - 0.00022 20.1 0.0 0.00037 19.3 0.0 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family TrkA_N PF02254.13 KFH45165.1 - 0.0021 18.0 0.0 0.004 17.1 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain GFO_IDH_MocA PF01408.17 KFH45165.1 - 0.0059 17.1 0.0 0.018 15.5 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding PF02629.14 KFH45165.1 - 0.0076 16.7 0.0 0.018 15.5 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain Semialdhyde_dh PF01118.19 KFH45165.1 - 0.025 14.8 0.0 0.056 13.7 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KFH45165.1 - 0.032 13.9 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 KFH45165.1 - 0.097 12.3 0.3 0.32 10.6 0.0 2.1 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.11 KFH45167.1 - 2.2e-28 98.9 36.8 4.6e-28 97.9 25.5 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KFH45167.1 - 9.1e-12 43.9 8.8 9.1e-12 43.9 6.1 1.7 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) SH3_1 PF00018.23 KFH45168.1 - 1.6e-26 91.4 0.0 1.1e-13 50.3 0.0 2.7 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.1 KFH45168.1 - 7.6e-19 67.0 0.0 9.2e-10 37.9 0.0 2.8 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 KFH45168.1 - 4.7e-14 52.1 0.0 8.8e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.12 KFH45168.1 - 3.9e-13 48.6 0.0 4.1e-07 29.3 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.19 KFH45168.1 - 5.7e-08 32.3 0.1 1.1e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 PB1 domain GST_N_3 PF13417.1 KFH45169.1 - 8e-24 83.6 0.1 4.4e-23 81.2 0.0 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFH45169.1 - 1.7e-17 63.1 0.3 2.5e-16 59.4 0.0 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFH45169.1 - 3.7e-09 36.3 0.2 8.2e-09 35.2 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KFH45169.1 - 2.8e-06 27.4 0.0 5.2e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFH45169.1 - 0.00023 21.0 0.0 0.00054 19.8 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFH45169.1 - 0.0015 18.9 0.1 0.0029 18.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain IBR PF01485.16 KFH45170.1 - 4.8e-07 29.5 20.1 9.5e-07 28.6 3.0 4.1 3 1 0 3 3 3 2 IBR domain LAT PF15234.1 KFH45170.1 - 0.018 14.5 1.6 0.04 13.3 1.1 1.5 1 0 0 1 1 1 0 Linker for activation of T-cells TSA PF03249.8 KFH45170.1 - 2.6 6.5 10.7 3.8 5.9 7.4 1.2 1 0 0 1 1 1 0 Type specific antigen TFIIA PF03153.8 KFH45170.1 - 8.7 6.1 21.7 13 5.5 15.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Fungal_trans PF04082.13 KFH45171.1 - 3.7e-16 58.7 0.0 6.3e-16 58.0 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH45171.1 - 1.4e-07 31.2 7.0 2.3e-07 30.6 4.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_10 PF05971.7 KFH45172.1 - 2.6e-60 204.0 0.0 3.6e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_26 PF13659.1 KFH45172.1 - 0.00011 22.2 0.0 0.00019 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFH45172.1 - 0.0025 17.2 0.0 0.0042 16.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.13 KFH45172.1 - 0.0056 16.2 0.0 0.009 15.6 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.2 KFH45172.1 - 0.022 15.3 0.0 0.042 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 KFH45172.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein PrmA PF06325.8 KFH45172.1 - 0.12 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 KFH45172.1 - 0.17 11.4 0.0 0.45 10.1 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain She9_MDM33 PF05546.6 KFH45173.1 - 1.3e-78 263.3 5.3 1.9e-78 262.8 3.7 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family BCAS2 PF05700.6 KFH45173.1 - 0.28 10.5 5.2 0.19 11.1 2.3 1.7 2 0 0 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) DUF4140 PF13600.1 KFH45173.1 - 6.9 7.1 11.2 1.7 9.1 0.8 3.2 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Tropomyosin PF00261.15 KFH45173.1 - 7 5.6 14.7 1.2 8.1 0.9 3.2 2 1 1 3 3 3 0 Tropomyosin SAC3_GANP PF03399.11 KFH45174.1 - 8.7e-65 218.1 0.1 1.1e-64 217.7 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KFH45174.1 - 7.2e-05 22.5 0.2 0.00089 19.0 0.0 2.2 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 Cellulase PF00150.13 KFH45175.1 - 2.2e-10 40.2 0.0 3.3e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) HTH_Tnp_Tc5 PF03221.11 KFH45176.1 - 4.1e-06 26.4 0.0 1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Acyl-CoA_dh_1 PF00441.19 KFH45177.1 - 4.8e-42 143.6 4.3 9.4e-42 142.6 3.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFH45177.1 - 2.3e-28 99.0 1.2 1.3e-27 96.6 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KFH45177.1 - 7.2e-17 61.8 1.7 7.2e-17 61.8 1.2 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFH45177.1 - 9.4e-16 57.0 0.1 1.8e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain HpaB_N PF11794.3 KFH45177.1 - 0.00034 20.1 0.1 0.0016 17.8 0.1 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal DUF3184 PF11380.3 KFH45177.1 - 0.079 10.8 0.1 0.12 10.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3184) Fungal_trans PF04082.13 KFH45178.1 - 1.6e-10 40.3 2.6 2.6e-10 39.6 1.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH45178.1 - 4e-07 29.8 11.4 8.7e-07 28.7 7.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFH45180.1 - 2.3e-13 49.6 0.0 3.6e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH45180.1 - 4.3e-06 26.5 6.6 8.9e-06 25.5 4.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PI31_Prot_N PF11566.3 KFH45181.1 - 6.2e-17 61.6 0.0 8.2e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 KFH45181.1 - 7.8e-17 61.6 20.6 7.8e-17 61.6 14.2 3.4 3 0 0 3 3 3 1 PI31 proteasome regulator HR1 PF02185.11 KFH45182.1 - 1.7e-29 101.3 12.8 1.3e-15 56.8 2.0 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 KFH45182.1 - 3.4e-19 68.2 28.6 3.6e-11 42.6 7.3 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase PF00069.20 KFH45182.1 - 1e-14 54.3 0.1 1.8e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH45182.1 - 6.7e-09 35.1 0.1 1.2e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PHD PF00628.24 KFH45182.1 - 9.1 6.0 25.2 0.064 12.9 5.8 2.4 2 0 0 2 2 2 0 PHD-finger ALG3 PF05208.8 KFH45183.1 - 2.6e-137 457.9 17.8 3.1e-137 457.7 12.4 1.0 1 0 0 1 1 1 1 ALG3 protein PAT1 PF09770.4 KFH45184.1 - 3.3e-219 730.1 36.4 6.2e-218 725.9 25.3 2.1 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Transp_cyt_pur PF02133.10 KFH45185.1 - 1.1e-150 502.1 36.7 1.2e-150 501.9 25.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PALP PF00291.20 KFH45186.1 - 2.3e-27 96.0 0.0 4.1e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.15 KFH45186.1 - 2.2e-08 34.4 0.0 8.5e-08 32.5 0.0 1.9 1 1 0 1 1 1 1 Rhodanese-like domain Thioredoxin PF00085.15 KFH45188.1 - 1.2e-26 92.3 0.0 1.6e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KFH45188.1 - 2.1e-08 34.3 0.4 1.2e-07 31.9 0.3 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KFH45188.1 - 1.7e-05 24.8 0.1 0.00019 21.4 0.1 2.0 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 KFH45188.1 - 0.00013 21.4 0.0 0.00016 21.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 KFH45188.1 - 0.00033 20.6 0.0 0.00051 20.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 KFH45188.1 - 0.0061 16.1 0.2 0.053 13.0 0.2 2.0 1 1 0 1 1 1 1 Redoxin Glutaredoxin PF00462.19 KFH45188.1 - 0.033 14.1 0.1 0.072 13.0 0.0 1.6 1 1 0 1 1 1 0 Glutaredoxin HyaE PF07449.6 KFH45188.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.3 1 1 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Nuf2 PF03800.9 KFH45189.1 - 9.7e-45 152.1 3.4 4e-44 150.1 0.0 2.5 2 0 0 2 2 2 1 Nuf2 family Bacillus_HBL PF05791.6 KFH45189.1 - 0.037 13.3 24.0 0.032 13.6 1.6 3.8 2 2 2 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) MFS_1 PF07690.11 KFH45190.1 - 3.9e-25 88.3 51.6 3.6e-14 52.2 17.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_transf_15 PF01793.11 KFH45191.1 - 8.7e-140 465.3 6.2 1e-139 465.1 4.3 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase CDI PF02234.14 KFH45191.1 - 0.025 14.3 0.8 0.094 12.5 0.4 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor DUF89 PF01937.14 KFH45192.1 - 1.4e-126 422.1 0.0 1.6e-126 421.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Adaptin_N PF01602.15 KFH45193.1 - 1.7e-104 350.0 0.0 2.1e-104 349.7 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 KFH45193.1 - 4.3e-12 46.1 5.0 0.00024 21.3 0.0 4.8 4 1 1 5 5 5 3 HEAT repeats HEAT PF02985.17 KFH45193.1 - 4.3e-07 29.4 1.3 0.042 13.9 0.0 5.5 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.1 KFH45193.1 - 8.9e-07 29.2 5.7 0.027 14.9 0.0 5.2 5 0 0 5 5 5 1 HEAT-like repeat Cohesin_HEAT PF12765.2 KFH45193.1 - 5.5e-05 23.0 0.7 0.078 12.9 0.0 3.6 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 KFH45193.1 - 0.045 13.5 0.1 2.9 7.7 0.0 3.0 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 KFH45193.1 - 0.057 12.7 0.2 4 6.7 0.0 3.0 2 1 0 2 2 2 0 CLASP N terminal DUF1980 PF09323.5 KFH45193.1 - 0.72 9.5 3.2 1.4 8.6 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DDHD PF02862.12 KFH45193.1 - 1.1 9.0 9.5 2.3 7.9 6.6 1.5 1 0 0 1 1 1 0 DDHD domain Nop14 PF04147.7 KFH45193.1 - 2 6.2 33.6 3.1 5.6 23.3 1.2 1 0 0 1 1 1 0 Nop14-like family Spore_coat_CotO PF14153.1 KFH45193.1 - 8.6 5.7 17.9 19 4.6 12.4 1.5 1 0 0 1 1 1 0 Spore coat protein CotO zf-MYND PF01753.13 KFH45194.1 - 1.5e-10 40.7 13.7 2.8e-10 39.8 9.5 1.4 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 KFH45194.1 - 5.6 6.3 7.4 14 5.1 5.2 1.7 1 1 0 1 1 1 0 Life-span regulatory factor zf-CCHC PF00098.18 KFH45195.1 - 4.2e-06 26.4 1.3 6.8e-06 25.7 0.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 KFH45195.1 - 0.041 13.6 0.2 0.041 13.6 0.1 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 KFH45195.1 - 0.14 11.8 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-AN1 PF01428.11 KFH45196.1 - 2.9e-25 87.8 21.5 7.9e-13 48.0 6.3 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 KFH45196.1 - 0.0018 18.4 14.6 0.059 13.5 4.1 2.4 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain IBR PF01485.16 KFH45196.1 - 0.011 15.6 19.6 0.014 15.2 1.8 2.6 2 1 0 2 2 2 0 IBR domain C1_4 PF07975.7 KFH45196.1 - 5.1 7.1 17.8 8.2 6.5 0.9 2.8 2 1 0 2 2 2 0 TFIIH C1-like domain Rad4 PF03835.10 KFH45197.1 - 6.9e-31 106.5 0.1 6.9e-31 106.5 0.0 2.2 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 KFH45197.1 - 2.4e-25 88.0 0.1 4.4e-25 87.1 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 KFH45197.1 - 3.1e-18 65.0 0.5 8.1e-18 63.7 0.4 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 KFH45197.1 - 3.1e-15 56.2 0.1 3.1e-15 56.2 0.1 3.7 4 0 0 4 4 4 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 KFH45197.1 - 0.0028 17.8 0.0 0.014 15.5 0.0 2.3 1 1 0 1 1 1 1 Transglutaminase-like superfamily Ribosom_S12_S23 PF00164.20 KFH45198.1 - 3.1e-41 139.6 0.7 4.4e-41 139.1 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 XAP5 PF04921.9 KFH45199.1 - 7.3e-78 261.4 0.2 1.3e-77 260.6 0.0 1.4 2 0 0 2 2 2 1 XAP5, circadian clock regulator DUF4604 PF15377.1 KFH45199.1 - 0.012 15.7 10.4 0.012 15.7 7.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4604) FLO_LFY PF01698.11 KFH45199.1 - 1.3 7.7 8.9 2 7.1 6.2 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein SR-25 PF10500.4 KFH45199.1 - 1.4 8.3 16.0 1.9 7.9 11.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Nucleo_P87 PF07267.6 KFH45199.1 - 3.2 6.3 7.8 4.9 5.7 5.4 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TATR PF03430.8 KFH45199.1 - 8 4.9 8.1 6.6 5.2 4.8 1.4 1 1 0 1 1 1 0 Trans-activating transcriptional regulator NAM-associated PF14303.1 KFH45199.1 - 8.5 6.6 12.6 14 5.9 8.7 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain AAA_10 PF12846.2 KFH45200.1 - 9.5e-09 35.0 0.0 0.00015 21.2 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain Zot PF05707.7 KFH45200.1 - 0.00068 19.1 0.0 0.01 15.2 0.0 2.4 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_22 PF13401.1 KFH45200.1 - 0.024 14.7 0.0 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KFH45200.1 - 0.025 14.0 0.0 0.068 12.6 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 KFH45200.1 - 0.051 12.6 0.0 0.12 11.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DUF87 PF01935.12 KFH45200.1 - 0.073 12.8 0.2 0.93 9.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 TrwB_AAD_bind PF10412.4 KFH45200.1 - 0.076 11.6 0.0 0.46 9.0 0.0 2.0 2 1 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain KilA-N PF04383.8 KFH45201.1 - 0.0056 16.2 0.5 0.031 13.8 0.0 2.5 2 1 0 2 2 2 1 KilA-N domain DUF1993 PF09351.5 KFH45201.1 - 2.7 7.8 5.1 2.3 8.0 2.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) UPF0075 PF03702.9 KFH45202.1 - 2.8e-84 283.1 0.0 3.2e-84 282.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) Glyco_hydro_12 PF01670.11 KFH45203.1 - 4e-27 94.9 0.1 4.7e-26 91.4 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 HORMA PF02301.13 KFH45204.1 - 1.3e-16 60.6 0.0 1.8e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 HORMA domain Sugar_tr PF00083.19 KFH45205.1 - 4.6e-60 203.4 12.3 5.2e-60 203.3 8.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH45205.1 - 6.8e-18 64.4 21.5 9.4e-18 64.0 14.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KFH45205.1 - 0.0011 17.5 1.2 0.0011 17.5 0.8 3.1 2 2 1 3 3 3 1 MFS/sugar transport protein Tim17 PF02466.14 KFH45205.1 - 0.16 12.0 10.5 0.25 11.4 0.1 3.4 3 0 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family MFS_1 PF07690.11 KFH45206.1 - 3.4e-31 108.2 32.8 3.4e-31 108.2 22.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH45206.1 - 6.4e-11 41.4 5.5 6.4e-11 41.4 3.8 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KFH45206.1 - 1.9e-08 33.0 1.7 3.1e-08 32.2 1.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GP41 PF00517.12 KFH45206.1 - 0.17 11.4 0.0 0.92 9.0 0.0 1.9 2 0 0 2 2 2 0 Retroviral envelope protein MFS_1 PF07690.11 KFH45207.1 - 3.6e-25 88.4 22.2 5.4e-20 71.4 12.8 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_P21 PF05313.7 KFH45207.1 - 0.12 11.6 1.0 0.23 10.7 0.7 1.4 1 0 0 1 1 1 0 Poxvirus P21 membrane protein MTP18 PF10558.4 KFH45208.1 - 1.7e-67 225.9 0.1 2.1e-67 225.6 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) AA_permease_2 PF13520.1 KFH45210.1 - 7.7e-87 291.5 33.7 9.6e-87 291.2 23.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFH45210.1 - 4.4e-15 54.9 29.7 8.2e-15 54.1 20.6 1.4 1 1 0 1 1 1 1 Amino acid permease HhH-GPD PF00730.20 KFH45211.1 - 3.4e-15 56.2 0.0 6.4e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF566 PF04484.7 KFH45211.1 - 5.3 6.4 8.7 10 5.5 6.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF566) GCS PF03074.11 KFH45212.1 - 1.4e-156 521.1 0.0 1.9e-156 520.7 0.0 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase Corona_I PF03187.9 KFH45212.1 - 0.22 10.6 0.0 0.37 9.9 0.0 1.2 1 0 0 1 1 1 0 Corona nucleocapsid I protein Clat_adaptor_s PF01217.15 KFH45214.1 - 4.6e-47 159.3 1.4 6.7e-47 158.7 0.3 1.6 2 0 0 2 2 2 1 Clathrin adaptor complex small chain DUF3287 PF11690.3 KFH45216.1 - 0.02 14.9 0.5 0.02 14.9 0.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) BicD PF09730.4 KFH45216.1 - 0.041 12.2 0.4 0.042 12.2 0.2 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D ORC6 PF05460.8 KFH45216.1 - 0.14 11.2 2.9 0.15 11.0 2.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) PBP1_TM PF14812.1 KFH45216.1 - 0.47 10.7 3.8 0.96 9.8 2.7 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3518 PF12031.3 KFH45216.1 - 0.66 8.7 2.5 1.1 8.0 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3518) HATPase_c PF02518.21 KFH45217.1 - 2e-29 101.5 0.0 6.4e-29 99.9 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KFH45217.1 - 4.9e-26 90.9 0.1 8.7e-26 90.1 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KFH45217.1 - 2.1e-13 50.0 0.0 4.8e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 KFH45217.1 - 6.2e-05 23.0 0.4 0.047 13.8 0.0 3.3 3 0 0 3 3 3 2 HAMP domain ZZ PF00569.12 KFH45218.1 - 1.5e-18 66.0 52.8 9.4e-06 25.0 5.2 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type Anp1 PF03452.9 KFH45220.1 - 4.3e-99 331.0 0.2 1.3e-98 329.4 0.1 1.6 1 1 0 1 1 1 1 Anp1 FHA PF00498.21 KFH45221.1 - 2.8e-09 36.9 0.0 4.8e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 FHA domain Gln-synt_C PF00120.19 KFH45222.1 - 3.4e-58 196.8 0.0 4.1e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 KFH45222.1 - 4.7e-19 67.7 0.0 7.6e-19 67.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain FAD_binding_2 PF00890.19 KFH45222.1 - 0.0025 16.7 0.0 0.0034 16.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain UPF0160 PF03690.8 KFH45223.1 - 8.9e-121 403.1 0.0 1e-120 402.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Tubulin PF00091.20 KFH45225.1 - 1.6e-67 227.4 0.1 7.9e-47 159.8 0.0 2.2 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFH45225.1 - 1.1e-45 154.7 0.3 2e-45 153.8 0.0 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KFH45225.1 - 4.8e-08 33.0 0.0 1.1e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KFH45225.1 - 0.064 12.7 0.0 0.22 10.9 0.0 1.9 2 0 0 2 2 2 0 Tubulin domain DUF2373 PF10180.4 KFH45226.1 - 1.9e-20 72.1 0.2 3.8e-20 71.1 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) DUF3482 PF11981.3 KFH45226.1 - 0.31 10.2 3.2 0.93 8.6 2.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Proteasome PF00227.21 KFH45227.1 - 1.4e-48 164.7 0.1 1.8e-48 164.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KFH45227.1 - 7e-10 38.0 0.1 7e-10 38.0 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature SCP2 PF02036.12 KFH45227.1 - 0.11 12.7 0.0 0.29 11.4 0.0 1.7 2 0 0 2 2 2 0 SCP-2 sterol transfer family DUF1602 PF07673.9 KFH45227.1 - 0.25 10.8 0.9 0.52 9.8 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1602) zf-B_box PF00643.19 KFH45228.1 - 0.059 13.2 1.0 0.8 9.6 0.1 2.2 2 0 0 2 2 2 0 B-box zinc finger zinc_ribbon_5 PF13719.1 KFH45228.1 - 0.31 10.6 3.4 1.5 8.5 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KFH45228.1 - 0.32 10.7 3.6 1.7 8.4 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.8 KFH45228.1 - 0.61 9.6 5.7 0.8 9.2 0.2 2.5 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.2 KFH45228.1 - 1.2 9.0 5.4 4.5 7.1 3.7 1.9 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 KFH45228.1 - 2.1 8.3 5.9 4.4 7.3 0.6 2.4 1 1 1 2 2 2 0 Zinc ribbon domain zinc_ribbon_6 PF14599.1 KFH45228.1 - 2.5 7.9 9.3 0.68 9.7 1.9 2.1 1 1 1 2 2 2 0 Zinc-ribbon TNFR_c6 PF00020.13 KFH45228.1 - 4.3 7.4 7.9 3.6 7.7 1.0 2.5 1 1 1 2 2 2 0 TNFR/NGFR cysteine-rich region Ribosomal_S27e PF01667.12 KFH45228.1 - 4.8 6.8 10.6 0.3 10.6 2.6 2.0 1 1 1 2 2 2 0 Ribosomal protein S27 UPF0546 PF10639.4 KFH45229.1 - 3.8e-35 120.1 0.2 4.9e-35 119.7 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 DUF1211 PF06736.6 KFH45229.1 - 0.075 13.1 0.1 0.26 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1211) EamA PF00892.15 KFH45229.1 - 0.078 13.0 8.6 0.062 13.3 2.5 2.4 3 0 0 3 3 3 0 EamA-like transporter family TPT PF03151.11 KFH45229.1 - 0.11 12.0 4.5 0.067 12.8 1.6 1.7 1 1 0 2 2 2 0 Triose-phosphate Transporter family F-box PF00646.28 KFH45230.1 - 3.4e-05 23.3 0.8 9.9e-05 21.8 0.5 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KFH45230.1 - 0.0035 17.0 1.6 0.013 15.1 0.3 2.3 2 0 0 2 2 2 1 F-box-like KorB_C PF06613.6 KFH45230.1 - 0.0046 16.3 0.1 2 7.9 0.0 3.1 4 0 0 4 4 4 2 KorB C-terminal beta-barrel domain PhyH PF05721.8 KFH45231.1 - 4.8e-63 213.0 0.0 5.6e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Aminotran_5 PF00266.14 KFH45232.1 - 5.9e-94 314.8 0.0 7.1e-94 314.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KFH45232.1 - 2.5e-07 30.1 0.0 3.6e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KFH45232.1 - 9.8e-05 21.5 0.0 0.00021 20.4 0.0 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 KFH45232.1 - 0.014 13.8 0.0 0.021 13.2 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Lactamase_B_2 PF12706.2 KFH45232.1 - 0.055 13.0 0.0 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain DUF92 PF01940.11 KFH45233.1 - 1.3e-67 227.2 0.9 1.6e-67 226.9 0.6 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 MFS_1 PF07690.11 KFH45234.1 - 2.3e-23 82.4 43.1 1.3e-22 80.0 29.1 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily ADIP PF11559.3 KFH45235.1 - 4e-40 137.1 3.1 4e-40 137.1 2.2 2.8 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding Phostensin_N PF13916.1 KFH45235.1 - 0.0036 17.2 3.8 0.012 15.6 1.9 2.4 2 0 0 2 2 2 1 PP1-regulatory protein, Phostensin N-terminal PhoU PF01895.14 KFH45235.1 - 1.8 9.0 5.9 39 4.7 0.1 3.6 2 1 1 3 3 3 0 PhoU domain TMF_DNA_bd PF12329.3 KFH45235.1 - 9.9 6.0 15.0 0.54 10.1 2.0 3.7 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding GATA PF00320.22 KFH45236.1 - 8.2e-15 53.8 3.4 1.5e-14 53.0 2.4 1.4 1 0 0 1 1 1 1 GATA zinc finger SnAC PF14619.1 KFH45236.1 - 0.15 12.2 2.0 0.37 11.0 1.4 1.7 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex DUF2011 PF09428.5 KFH45237.1 - 0.027 14.3 0.0 0.072 12.9 0.0 1.8 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF2011) DEAD PF00270.24 KFH45238.1 - 7.8e-34 116.5 0.0 2.8e-33 114.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFH45238.1 - 1.9e-21 75.7 0.0 3.6e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KFH45238.1 - 7.1e-05 22.4 1.5 0.003 17.2 0.0 2.9 2 1 1 3 3 3 1 Part of AAA domain CMS1 PF14617.1 KFH45238.1 - 0.00055 19.0 0.0 0.0011 18.1 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.10 KFH45238.1 - 0.0088 15.8 0.0 0.058 13.2 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 KFH45238.1 - 0.023 14.6 0.0 0.059 13.3 0.0 1.6 2 0 0 2 2 2 0 Helicase C-terminal domain AAA_22 PF13401.1 KFH45238.1 - 0.055 13.5 0.1 0.8 9.8 0.0 2.6 2 1 0 2 2 2 0 AAA domain Zn_clus PF00172.13 KFH45239.1 - 2.1e-08 33.9 4.8 3.1e-08 33.3 3.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2076 PF09849.4 KFH45239.1 - 1.3 9.0 8.2 3 7.8 5.7 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Syja_N PF02383.13 KFH45240.1 - 1.9e-94 316.0 0.0 2.6e-94 315.5 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 KFH45240.1 - 6e-34 115.8 0.0 1.1e-33 115.0 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase LRR_8 PF13855.1 KFH45241.1 - 0.0042 16.8 6.2 4.1 7.2 0.0 4.0 4 0 0 4 4 4 2 Leucine rich repeat DUF4522 PF15022.1 KFH45241.1 - 0.0098 15.5 0.2 2.3 7.9 0.0 2.7 1 1 0 2 2 2 2 Protein of unknown function (DUF4522) Recep_L_domain PF01030.19 KFH45241.1 - 0.032 14.2 8.7 0.38 10.7 0.0 3.8 2 2 1 3 3 3 0 Receptor L domain LRR_4 PF12799.2 KFH45241.1 - 0.19 11.3 11.7 8.4 6.1 1.3 4.6 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFH45241.1 - 0.29 11.3 3.4 3.1 8.1 0.3 3.6 3 0 0 3 3 3 0 Leucine Rich Repeat WD40 PF00400.27 KFH45242.1 - 5.3e-42 140.2 12.5 1.1e-11 44.1 0.0 6.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 KFH45242.1 - 4.8e-06 25.0 3.5 0.14 10.2 0.1 3.9 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFH45242.1 - 0.015 14.1 0.2 0.44 9.2 0.0 2.6 1 1 1 2 2 2 0 Nup133 N terminal like DUF3312 PF11768.3 KFH45242.1 - 0.062 11.5 0.0 0.09 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) PSCyt3 PF07627.6 KFH45243.1 - 0.069 13.0 0.0 0.08 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1588) p450 PF00067.17 KFH45244.1 - 3.4e-10 39.0 0.0 3.4e-07 29.1 0.0 2.4 3 0 0 3 3 3 2 Cytochrome P450 Transketolase_N PF00456.16 KFH45245.1 - 2.6e-152 506.4 0.0 3.3e-152 506.1 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KFH45245.1 - 1.9e-44 151.2 0.0 3.3e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KFH45245.1 - 3.2e-12 46.4 0.0 6.9e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 KFH45245.1 - 3.4e-07 29.4 0.0 0.00017 20.6 0.0 2.2 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase Mur_ligase_C PF02875.16 KFH45245.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain DUF1264 PF06884.6 KFH45246.1 - 6.3e-59 198.2 0.2 6.9e-59 198.1 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) Maf1 PF09174.5 KFH45247.1 - 6.8e-53 179.1 0.0 9.6e-53 178.6 0.0 1.2 1 0 0 1 1 1 1 Maf1 regulator Btz PF09405.5 KFH45248.1 - 1.9e-26 92.6 3.4 1.9e-26 92.6 2.3 1.8 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding Gln-synt_C PF00120.19 KFH45249.1 - 4.9e-49 166.8 0.0 9.7e-49 165.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.9 KFH45249.1 - 1.7e-28 99.9 0.2 3.6e-28 98.9 0.2 1.6 1 0 0 1 1 1 1 Amidohydrolase Ran_BP1 PF00638.13 KFH45250.1 - 1.4e-11 44.4 0.2 2.9e-11 43.4 0.1 1.5 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 KFH45250.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 WH1 domain Endosulfine PF04667.12 KFH45252.1 - 8.8e-21 73.6 0.0 1.3e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region CN_hydrolase PF00795.17 KFH45253.1 - 2.1e-32 111.9 0.0 4.8e-32 110.7 0.0 1.5 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase CsbD PF05532.7 KFH45255.1 - 2.7e-17 62.1 22.9 3.4e-07 29.8 0.1 4.9 4 1 0 4 4 4 4 CsbD-like Toxin_11 PF07473.6 KFH45256.1 - 0.0041 16.9 0.7 0.0075 16.0 0.5 1.5 1 0 0 1 1 1 1 Spasmodic peptide gm9a Spermine_synth PF01564.12 KFH45257.1 - 3.3e-90 301.3 0.1 1.4e-79 266.5 0.0 2.1 2 0 0 2 2 2 2 Spermine/spermidine synthase Methyltransf_18 PF12847.2 KFH45257.1 - 0.00025 21.5 0.0 0.00044 20.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.11 KFH45257.1 - 0.0029 16.6 0.0 0.0045 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_31 PF13847.1 KFH45257.1 - 0.0043 16.6 0.0 0.0073 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH45257.1 - 0.013 15.9 0.3 0.093 13.2 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_2 PF00891.13 KFH45257.1 - 0.14 11.2 0.1 0.57 9.3 0.1 1.9 1 1 1 2 2 2 0 O-methyltransferase RRP7 PF12923.2 KFH45258.1 - 2.7e-31 108.2 13.9 2.7e-31 108.2 9.6 2.1 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_6 PF14259.1 KFH45258.1 - 0.018 15.0 0.0 2.4 8.2 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Claudin_2 PF13903.1 KFH45259.1 - 0.00031 20.5 5.2 0.00064 19.4 3.6 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction SUR7 PF06687.7 KFH45259.1 - 0.019 14.5 0.9 1.2 8.6 0.2 2.1 1 1 1 2 2 2 0 SUR7/PalI family DUF3112 PF11309.3 KFH45259.1 - 0.027 14.2 0.6 0.027 14.2 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) MARVEL PF01284.18 KFH45259.1 - 0.036 13.9 13.9 0.39 10.5 9.5 2.3 1 1 0 1 1 1 0 Membrane-associating domain 5TM-5TMR_LYT PF07694.7 KFH45259.1 - 0.44 9.8 9.6 0.25 10.6 2.7 2.1 2 0 0 2 2 2 0 5TMR of 5TMR-LYT DUF4149 PF13664.1 KFH45259.1 - 0.66 10.0 5.8 2.3 8.3 0.9 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) DUF3816 PF12822.2 KFH45259.1 - 6.2 6.6 11.4 57 3.5 7.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) DUF3995 PF13160.1 KFH45259.1 - 6.4 6.8 10.2 0.99 9.4 1.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3995) BAR PF03114.13 KFH45260.1 - 1.2e-66 224.5 7.5 1.5e-66 224.1 5.2 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 KFH45260.1 - 1.1e-14 53.4 0.1 2.1e-14 52.6 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFH45260.1 - 1.2e-13 50.4 0.1 2e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFH45260.1 - 1.3e-08 34.2 0.0 2.6e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF533 PF04391.7 KFH45260.1 - 0.35 10.2 2.6 0.2 11.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF533) GMC_oxred_N PF00732.14 KFH45261.1 - 1.9e-43 148.6 0.0 9.6e-30 103.7 0.0 3.1 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 KFH45261.1 - 2.9e-36 124.8 0.1 5e-36 124.1 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KFH45261.1 - 2.9e-07 29.7 0.2 6.1e-05 22.0 0.1 3.4 3 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFH45261.1 - 5.6e-06 25.4 0.0 0.0041 16.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 KFH45261.1 - 5.1e-05 23.2 0.0 0.00014 21.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFH45261.1 - 0.00063 19.7 0.1 0.0019 18.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KFH45261.1 - 0.0045 15.9 0.0 0.0073 15.2 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 KFH45261.1 - 0.041 12.5 0.0 0.058 12.0 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 KFH45261.1 - 0.08 12.7 0.0 1 9.1 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 KFH45261.1 - 0.11 11.6 0.1 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FTHFS PF01268.14 KFH45262.1 - 1.1e-257 855.4 0.2 1.1e-257 855.4 0.1 1.5 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 KFH45262.1 - 1.9e-67 225.3 0.7 1.9e-67 225.3 0.5 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 KFH45262.1 - 1.2e-28 99.5 0.3 2.8e-28 98.2 0.2 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GTP_EFTU PF00009.22 KFH45262.1 - 0.025 14.0 0.3 0.06 12.7 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Zn_clus PF00172.13 KFH45263.1 - 1.8e-06 27.7 10.9 1.8e-06 27.7 7.5 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain G-alpha PF00503.15 KFH45264.1 - 2.6e-120 401.7 0.2 3.2e-120 401.4 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFH45264.1 - 3.4e-14 52.4 0.6 3.3e-08 32.9 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFH45264.1 - 0.00039 19.6 0.1 0.24 10.5 0.0 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.13 KFH45264.1 - 0.019 14.4 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 KFH45264.1 - 0.024 14.1 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 KFH45264.1 - 0.03 13.7 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain IFRD PF05004.8 KFH45265.1 - 4.6e-12 45.6 0.0 6.8e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Cnd3 PF12719.2 KFH45265.1 - 0.0017 17.3 0.0 0.0047 15.9 0.0 1.7 1 1 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain DUF765 PF05570.6 KFH45265.1 - 0.032 14.1 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF765) Adaptin_N PF01602.15 KFH45265.1 - 0.046 12.0 0.0 0.077 11.3 0.0 1.2 1 0 0 1 1 1 0 Adaptin N terminal region ATP-synt_C PF00137.16 KFH45266.1 - 1.6e-28 98.4 26.9 1.3e-18 66.6 8.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Terpene_synth_C PF03936.11 KFH45267.1 - 0.00093 18.5 1.3 0.17 11.1 0.3 2.6 2 1 0 2 2 2 2 Terpene synthase family, metal binding domain Penicillinase_R PF03965.11 KFH45267.1 - 0.045 13.8 0.2 0.15 12.2 0.1 1.9 1 0 0 1 1 1 0 Penicillinase repressor G-patch PF01585.18 KFH45268.1 - 2.1e-13 49.8 0.1 5.8e-13 48.4 0.0 1.8 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.1 KFH45268.1 - 1.3e-06 28.1 0.1 2.7e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFH45268.1 - 0.00012 21.5 0.1 0.00027 20.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH45268.1 - 0.0031 17.4 0.0 0.0072 16.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3115 PF11312.3 KFH45270.1 - 2e-81 273.2 0.0 4.3e-81 272.2 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3115) SNF2_N PF00176.18 KFH45271.1 - 4.5e-71 239.0 0.3 4.5e-71 239.0 0.2 1.9 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFH45271.1 - 6.6e-17 61.1 0.0 2.2e-16 59.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFH45271.1 - 5.4e-07 29.6 0.0 5.4e-07 29.6 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 KFH45271.1 - 0.0004 19.2 0.0 0.0017 17.2 0.0 2.0 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 TFIIA PF03153.8 KFH45271.1 - 0.17 11.7 13.1 0.014 15.3 2.5 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit AT_hook PF02178.14 KFH45271.1 - 0.55 10.0 7.9 3.1 7.7 5.5 2.4 1 0 0 1 1 1 0 AT hook motif tRNA_bind PF01588.15 KFH45272.1 - 8.5e-22 76.8 0.2 3.9e-21 74.7 0.1 2.0 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 KFH45272.1 - 2.7e-07 30.9 0.1 1.3e-06 28.7 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFH45272.1 - 9.2e-05 22.2 0.0 0.00029 20.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFH45272.1 - 0.00069 19.5 0.1 0.0026 17.6 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain NAM-associated PF14303.1 KFH45272.1 - 0.091 13.0 4.6 0.15 12.3 3.2 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Chitin_synth_1 PF01644.12 KFH45273.1 - 9.6e-71 236.8 0.0 1.4e-70 236.2 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 KFH45273.1 - 1.6e-30 106.0 0.0 4.3e-25 88.0 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 KFH45273.1 - 2.3e-25 88.0 0.2 5.1e-25 86.9 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 KFH45273.1 - 2.3e-12 47.0 7.1 2.1e-11 43.9 4.9 2.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KFH45273.1 - 3.4e-09 36.8 0.0 8.4e-09 35.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Oligomerisation PF02410.10 KFH45274.1 - 1.8e-05 24.6 0.0 0.00028 20.8 0.0 2.5 1 1 0 1 1 1 1 Oligomerisation domain Iso_dh PF00180.15 KFH45275.1 - 3.5e-85 286.0 0.0 3.9e-85 285.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ribosomal_L1 PF00687.16 KFH45276.1 - 5.6e-61 205.6 0.1 5.6e-61 205.6 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family bZIP_1 PF00170.16 KFH45278.1 - 1.2e-05 25.1 6.1 3.3e-05 23.7 4.2 1.8 1 0 0 1 1 1 1 bZIP transcription factor 23S_rRNA_IVP PF05635.6 KFH45278.1 - 0.093 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 23S rRNA-intervening sequence protein bZIP_2 PF07716.10 KFH45278.1 - 1.1 9.1 10.3 0.085 12.6 3.7 1.9 2 0 0 2 2 2 0 Basic region leucine zipper CRAL_TRIO PF00650.15 KFH45279.1 - 1.1e-25 89.9 0.0 1.7e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KFH45279.1 - 9.4e-10 38.4 0.0 2.1e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain PHP PF02811.14 KFH45280.1 - 8.2e-08 32.2 0.0 2.4e-07 30.6 0.0 1.8 1 1 0 1 1 1 1 PHP domain Glyco_tranf_2_4 PF13704.1 KFH45280.1 - 0.071 13.4 0.0 13 6.1 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 adh_short PF00106.20 KFH45281.1 - 7.7e-19 68.2 0.3 1.4e-18 67.4 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH45281.1 - 1.8e-09 37.5 0.3 3.1e-09 36.7 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFH45281.1 - 5.9e-09 35.7 0.0 7.7e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFH45281.1 - 1.1e-08 35.2 0.2 1.6e-08 34.7 0.2 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 KFH45281.1 - 7e-06 25.9 0.1 2.1e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Glyco_transf_4 PF13439.1 KFH45281.1 - 0.0048 16.6 0.0 0.015 14.9 0.0 1.7 1 1 1 2 2 2 1 Glycosyltransferase Family 4 Eno-Rase_NADH_b PF12242.3 KFH45281.1 - 0.011 15.5 0.5 0.78 9.5 0.0 2.4 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TrkA_N PF02254.13 KFH45281.1 - 0.023 14.7 0.1 0.041 13.8 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain DUF1771 PF08590.5 KFH45281.1 - 0.027 14.4 1.6 0.089 12.8 1.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) 3HCDH_N PF02737.13 KFH45281.1 - 0.03 13.9 0.2 0.047 13.3 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 KFH45281.1 - 0.039 13.3 0.1 0.059 12.8 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Flavodoxin_5 PF12724.2 KFH45281.1 - 0.14 12.1 0.2 3.6 7.5 0.0 2.3 1 1 1 2 2 2 0 Flavodoxin domain GalP_UDP_transf PF01087.17 KFH45282.1 - 2.6e-69 232.9 0.1 7.9e-67 224.8 0.0 2.2 2 0 0 2 2 2 2 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 KFH45282.1 - 4.8e-55 185.6 0.0 1.4e-54 184.1 0.0 1.7 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 KFH45282.1 - 0.025 15.1 0.0 0.09 13.3 0.0 2.0 2 0 0 2 2 2 0 HIT domain PWI PF01480.12 KFH45283.1 - 4.1e-10 39.6 0.1 9.9e-10 38.3 0.1 1.7 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.17 KFH45283.1 - 0.065 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH45283.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) adh_short PF00106.20 KFH45284.1 - 2.8e-20 72.9 0.0 3.9e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH45284.1 - 1.4e-11 44.6 0.0 2e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH45284.1 - 3.6e-06 26.7 0.0 6.5e-06 25.9 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFH45284.1 - 0.00056 19.9 0.1 0.0025 17.8 0.1 2.1 2 1 0 2 2 2 1 NADH(P)-binding Shikimate_DH PF01488.15 KFH45284.1 - 0.0039 17.2 0.0 0.0083 16.2 0.0 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 KFH45284.1 - 0.0057 16.3 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 KFH45284.1 - 0.0087 14.9 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 KFH45284.1 - 0.017 14.0 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_2 PF03446.10 KFH45284.1 - 0.027 14.3 0.0 0.071 12.9 0.0 1.7 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Epimerase PF01370.16 KFH45284.1 - 0.074 12.4 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Zn_clus PF00172.13 KFH45287.1 - 0.0059 16.4 5.8 0.01 15.6 4.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 KFH45288.1 - 1.5e-33 116.0 0.0 1.9e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH45288.1 - 2.5e-11 43.1 0.0 4.3e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFH45288.1 - 0.015 15.0 0.0 0.42 10.3 0.0 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KFH45288.1 - 0.062 12.2 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 KFH45288.1 - 0.078 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mmp37 PF09139.6 KFH45289.1 - 2.8e-126 421.0 0.0 3.5e-126 420.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 SH3BGR PF04908.10 KFH45290.1 - 0.00044 20.1 0.3 0.0025 17.7 0.0 2.4 2 1 1 3 3 3 1 SH3-binding, glutamic acid-rich protein CDC27 PF09507.5 KFH45290.1 - 2.3 7.3 30.9 2.9 6.9 21.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Borrelia_P83 PF05262.6 KFH45290.1 - 5.4 5.1 17.7 6.5 4.9 12.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DPPIV_N PF00930.16 KFH45291.1 - 1.5e-104 349.3 0.2 2.1e-104 348.9 0.1 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 KFH45291.1 - 7e-53 179.0 1.3 1e-52 178.4 0.4 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFH45291.1 - 7.7e-11 41.9 0.5 2.2e-10 40.4 0.2 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFH45291.1 - 4.3e-07 30.0 6.9 1.4e-06 28.3 2.8 2.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KFH45291.1 - 0.0041 16.5 0.3 0.029 13.7 0.1 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Apc4_WD40 PF12894.2 KFH45291.1 - 0.0073 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain UPF0121 PF03661.8 KFH45292.1 - 4.2e-13 49.0 0.6 5.8e-13 48.6 0.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) YGGT PF02325.12 KFH45292.1 - 0.49 10.3 6.0 0.53 10.2 0.1 2.7 2 1 0 2 2 2 0 YGGT family Phosphodiest PF01663.17 KFH45294.1 - 6.7e-13 48.6 0.8 1.6e-12 47.4 0.1 1.8 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 KFH45294.1 - 0.00015 21.2 0.1 0.00024 20.5 0.1 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 KFH45294.1 - 0.00042 19.6 0.0 0.00093 18.4 0.0 1.5 1 1 0 1 1 1 1 Sulfatase Epimerase PF01370.16 KFH45295.1 - 7e-46 156.5 0.0 1.1e-45 155.9 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 KFH45295.1 - 6.9e-23 80.3 0.1 1.4e-22 79.3 0.1 1.6 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 KFH45295.1 - 1.4e-16 60.0 0.0 6.2e-16 57.9 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KFH45295.1 - 5.5e-14 51.7 0.0 7.5e-12 44.7 0.0 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KFH45295.1 - 7.7e-14 51.2 0.0 1.2e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 KFH45295.1 - 7.4e-12 45.5 0.0 1.2e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KFH45295.1 - 3.4e-09 36.0 0.0 1.7e-08 33.7 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 KFH45295.1 - 7.2e-09 35.5 0.0 1.4e-08 34.6 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFH45295.1 - 8.4e-09 35.6 0.0 1.6e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding UDPG_MGDP_dh_N PF03721.9 KFH45295.1 - 0.0013 18.1 0.1 0.0025 17.2 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NmrA PF05368.8 KFH45295.1 - 0.0034 16.6 0.0 0.026 13.7 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family adh_short_C2 PF13561.1 KFH45295.1 - 0.012 15.4 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DAO PF01266.19 KFH45295.1 - 0.08 11.8 0.3 0.13 11.1 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Rhodanese PF00581.15 KFH45296.1 - 1.5e-16 60.7 0.0 1.9e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain DUF1957 PF09210.6 KFH45296.1 - 0.047 13.7 0.0 0.098 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1957) Ank_2 PF12796.2 KFH45298.1 - 1.1e-67 224.4 14.7 2.2e-10 40.7 0.0 15.2 8 5 5 13 13 13 13 Ankyrin repeats (3 copies) Ank PF00023.25 KFH45298.1 - 1.8e-31 106.3 29.7 4.8e-06 26.1 0.0 19.6 19 2 0 19 19 19 8 Ankyrin repeat Ank_3 PF13606.1 KFH45298.1 - 1.5e-24 83.5 19.7 0.0002 21.2 0.0 19.6 20 2 2 22 22 22 5 Ankyrin repeat Ank_5 PF13857.1 KFH45298.1 - 3.8e-21 74.6 19.8 3.6e-08 33.3 0.0 14.8 14 2 2 16 16 16 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFH45298.1 - 1.7e-19 69.8 21.4 0.17 12.4 0.0 17.1 15 4 3 18 18 17 6 Ankyrin repeats (many copies) RNA_pol PF00940.14 KFH45300.1 - 7.8e-159 528.4 0.0 1.2e-158 527.9 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 KFH45300.1 - 4.5e-72 243.0 0.3 6.8e-72 242.4 0.2 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal DHHA2 PF02833.9 KFH45302.1 - 1.1e-25 90.3 0.0 1.7e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 KFH45302.1 - 1.6e-08 34.3 0.0 2.7e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 DHH family DUF1769 PF08588.5 KFH45303.1 - 0.042 13.8 0.1 0.056 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) DEAD PF00270.24 KFH45304.1 - 2.9e-44 150.5 0.0 5.1e-44 149.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KFH45304.1 - 1.9e-24 84.9 0.1 4.3e-24 83.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KFH45304.1 - 3.6e-22 78.0 0.0 8.4e-22 76.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFH45304.1 - 0.00055 19.8 2.1 0.0018 18.1 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Trehalase PF01204.13 KFH45305.1 - 1.1e-124 416.9 0.3 1.1e-123 413.5 0.2 2.0 1 1 0 1 1 1 1 Trehalase GDE_C PF06202.9 KFH45305.1 - 4.3e-05 22.3 0.0 0.00078 18.2 0.0 2.1 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase Cytochrom_B561 PF03188.11 KFH45306.1 - 6.3e-05 22.8 10.5 6.3e-05 22.8 7.3 1.6 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 YbjQ_1 PF01906.12 KFH45307.1 - 2.5e-24 85.7 0.0 3.2e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Putative heavy-metal-binding MaoC_dehydratas PF01575.14 KFH45308.1 - 0.002 17.4 0.1 0.0044 16.4 0.1 1.5 1 0 0 1 1 1 1 MaoC like domain TauD PF02668.11 KFH45309.1 - 0.00026 20.7 0.0 0.00027 20.7 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family QRPTase_C PF01729.14 KFH45310.1 - 1.1e-53 181.1 0.1 1.4e-53 180.8 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 KFH45310.1 - 1.7e-20 72.6 0.1 7.9e-20 70.4 0.0 2.1 2 1 1 3 3 3 1 Quinolinate phosphoribosyl transferase, N-terminal domain PRAI PF00697.17 KFH45310.1 - 0.014 14.9 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Palm_thioest PF02089.10 KFH45311.1 - 6.1e-54 182.8 0.0 7.4e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.6 KFH45311.1 - 0.0027 16.8 0.0 0.0042 16.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_5 PF12695.2 KFH45311.1 - 0.074 12.7 0.0 5.3 6.7 0.0 2.3 1 1 1 2 2 2 0 Alpha/beta hydrolase family SurE PF01975.12 KFH45312.1 - 4e-40 137.2 0.0 7.3e-40 136.3 0.0 1.4 2 0 0 2 2 2 1 Survival protein SurE Erg28 PF03694.8 KFH45313.1 - 9.9e-42 141.4 0.2 1.2e-41 141.1 0.1 1.1 1 0 0 1 1 1 1 Erg28 like protein ABC_tran PF00005.22 KFH45314.1 - 2e-47 160.9 0.2 2.3e-24 86.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 KFH45314.1 - 4.3e-26 91.7 32.0 8.1e-20 71.1 12.6 2.4 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 KFH45314.1 - 3.3e-22 79.7 0.5 7.5e-05 22.8 0.0 4.4 3 1 0 4 4 4 4 AAA domain AAA_29 PF13555.1 KFH45314.1 - 1.7e-10 40.2 0.8 7.3e-05 22.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KFH45314.1 - 1.5e-07 31.9 2.2 0.0063 16.8 0.1 2.4 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KFH45314.1 - 1.5e-07 30.8 1.7 0.16 11.1 0.1 3.9 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KFH45314.1 - 1.7e-05 24.0 0.0 0.083 11.9 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 KFH45314.1 - 2.9e-05 23.3 0.4 0.2 10.8 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 KFH45314.1 - 0.00021 21.3 0.1 0.51 10.2 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.1 KFH45314.1 - 0.007 15.9 0.3 2 7.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KFH45314.1 - 0.0076 16.3 0.2 2.5 8.2 0.1 3.1 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KFH45314.1 - 0.028 13.7 0.1 6.8 6.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KFH45314.1 - 0.034 13.2 0.2 4.6 6.2 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.1 KFH45314.1 - 0.075 12.8 2.5 17 5.2 0.0 3.5 3 0 0 3 3 3 0 Part of AAA domain SRP54 PF00448.17 KFH45314.1 - 0.088 12.2 0.3 13 5.2 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_28 PF13521.1 KFH45314.1 - 0.15 12.0 0.1 15 5.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KFH45314.1 - 0.17 11.7 0.2 27 4.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 KFH45314.1 - 0.18 11.7 2.0 30 4.6 0.0 3.9 3 2 0 3 3 3 0 Putative exonuclease SbcCD, C subunit G-alpha PF00503.15 KFH45314.1 - 0.49 9.0 0.0 1.8 7.1 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit AAA_13 PF13166.1 KFH45314.1 - 2.1 6.6 0.2 27 3.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain 4HBT_3 PF13622.1 KFH45315.1 - 6.7e-39 134.1 0.8 8.4e-39 133.8 0.6 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 KFH45315.1 - 0.046 13.3 0.0 0.5 9.9 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA thioesterase Nucleoporin_C PF03177.9 KFH45316.1 - 3.2e-131 438.7 0.9 4e-131 438.3 0.6 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 KFH45316.1 - 1.7e-82 277.4 1.0 2.2e-82 277.0 0.7 1.1 1 0 0 1 1 1 1 Nup133 N terminal like Hist_deacetyl PF00850.14 KFH45317.1 - 7.8e-58 196.2 0.1 1.2e-57 195.5 0.1 1.3 1 0 0 1 1 1 1 Histone deacetylase domain DUF999 PF06198.6 KFH45317.1 - 0.072 12.8 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF999) DUF2781 PF10914.3 KFH45318.1 - 1e-19 70.8 7.5 1.2e-19 70.6 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Clathrin PF00637.15 KFH45319.1 - 2e-206 675.9 39.9 6.2e-34 116.6 1.2 7.3 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.15 KFH45319.1 - 4.7e-30 101.7 0.9 7.1e-05 22.8 0.0 7.8 7 0 0 7 7 7 7 Clathrin propeller repeat Clathrin_H_link PF13838.1 KFH45319.1 - 6.4e-30 102.8 2.1 9.6e-30 102.2 0.3 2.4 2 0 0 2 2 2 1 Clathrin-H-link TPR_12 PF13424.1 KFH45319.1 - 7.6e-06 25.7 1.9 1.6 8.6 0.0 6.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFH45319.1 - 0.00071 19.8 4.0 7.1 7.0 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFH45319.1 - 0.0009 19.6 9.5 17 6.3 0.0 8.4 9 1 1 10 10 10 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFH45319.1 - 0.0047 16.6 11.2 2.2 8.3 0.0 6.7 8 0 0 8 8 8 1 Tetratricopeptide repeat PPR PF01535.15 KFH45319.1 - 0.022 14.7 0.6 83 3.4 0.0 5.4 6 0 0 6 6 6 0 PPR repeat TPR_2 PF07719.12 KFH45319.1 - 1.5 8.9 9.9 13 6.0 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFH45319.1 - 3.6 7.3 8.8 9.7 5.9 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat KIAA1328 PF15369.1 KFH45321.1 - 5.3 6.7 9.7 25 4.5 3.8 2.2 2 0 0 2 2 2 0 Uncharacterised protein KIAA1328 zf-RING_2 PF13639.1 KFH45322.1 - 1.3e-09 37.7 7.3 3.7e-09 36.2 5.1 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFH45322.1 - 1.6e-07 31.2 2.7 3.9e-07 30.0 1.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 KFH45322.1 - 1.6e-05 24.7 8.0 4.5e-05 23.3 5.6 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 KFH45322.1 - 0.00016 21.4 3.0 0.00048 19.9 2.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 KFH45322.1 - 0.001 19.0 8.0 0.0022 17.9 5.5 1.6 1 0 0 1 1 1 1 RING-variant domain C1_1 PF00130.17 KFH45322.1 - 0.0016 18.1 2.5 0.0016 18.1 1.7 1.8 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4 PF00097.20 KFH45322.1 - 0.0023 17.5 9.8 0.0023 17.5 6.8 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFH45322.1 - 0.0047 16.5 4.7 0.0047 16.5 3.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFH45322.1 - 0.0061 16.5 8.8 0.0061 16.5 6.1 2.1 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFH45322.1 - 0.11 12.2 8.7 0.22 11.3 6.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING-like PF08746.6 KFH45322.1 - 0.12 12.3 7.7 0.24 11.4 5.3 1.5 1 0 0 1 1 1 0 RING-like domain Baculo_RING PF05883.6 KFH45322.1 - 0.22 11.3 1.4 0.47 10.2 1.0 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_4 PF14570.1 KFH45322.1 - 3.9 7.1 7.3 74 3.0 5.1 2.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 KFH45322.1 - 5 6.9 6.8 9.8 5.9 4.7 1.5 1 0 0 1 1 1 0 PHD-finger AAA PF00004.24 KFH45323.1 - 4.2e-51 172.6 0.0 1.3e-43 148.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KFH45323.1 - 5.6e-05 23.9 0.0 0.00044 21.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KFH45323.1 - 9.1e-05 21.9 0.1 0.0011 18.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KFH45323.1 - 0.00025 20.1 0.0 0.00064 18.8 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KFH45323.1 - 0.00051 20.0 0.9 0.025 14.5 0.0 3.4 3 1 0 4 4 3 1 AAA ATPase domain AAA_22 PF13401.1 KFH45323.1 - 0.00067 19.8 0.0 0.0036 17.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.12 KFH45323.1 - 0.00086 18.2 0.0 0.0017 17.2 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_19 PF13245.1 KFH45323.1 - 0.00089 18.9 0.0 0.017 14.8 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain IstB_IS21 PF01695.12 KFH45323.1 - 0.0011 18.4 0.0 0.0023 17.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 KFH45323.1 - 0.003 17.4 0.0 0.0071 16.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 KFH45323.1 - 0.0089 16.1 0.0 0.033 14.3 0.0 2.0 2 0 0 2 2 1 1 RNA helicase TIP49 PF06068.8 KFH45323.1 - 0.011 14.5 0.0 0.017 13.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_5 PF07728.9 KFH45323.1 - 0.016 14.9 0.0 0.078 12.7 0.0 2.3 2 1 0 2 2 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KFH45323.1 - 0.022 13.9 0.1 0.047 12.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 KFH45323.1 - 0.033 13.2 0.0 0.067 12.2 0.0 1.4 1 0 0 1 1 1 0 KaiC PhoH PF02562.11 KFH45323.1 - 0.035 13.3 0.0 0.094 11.9 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein AAA_14 PF13173.1 KFH45323.1 - 0.045 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KFH45323.1 - 0.047 13.6 0.0 0.14 12.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.1 KFH45323.1 - 0.069 13.0 0.1 0.23 11.3 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 KFH45323.1 - 0.07 13.4 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KFH45323.1 - 0.16 11.5 0.2 0.28 10.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.12 KFH45323.1 - 0.51 8.8 0.0 0.83 8.1 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase Daxx PF03344.10 KFH45323.1 - 2 6.8 4.3 4.3 5.7 3.0 1.4 1 0 0 1 1 1 0 Daxx Family Acid_PPase PF12689.2 KFH45324.1 - 1.7e-57 193.7 0.0 2.6e-57 193.1 0.0 1.3 1 1 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.1 KFH45324.1 - 0.081 13.1 0.1 7.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase muHD PF10291.4 KFH45325.1 - 8.1e-61 205.4 0.0 1.2e-60 204.8 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 KFH45325.1 - 1.5e-08 34.7 0.2 3.7e-08 33.4 0.1 1.7 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Vps5 PF09325.5 KFH45325.1 - 0.0014 17.9 0.3 0.0029 16.8 0.2 1.5 1 0 0 1 1 1 1 Vps5 C terminal like Muted PF14942.1 KFH45325.1 - 0.097 12.5 5.3 0.034 14.0 1.4 1.8 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Prominin PF05478.6 KFH45325.1 - 2.3 5.6 2.8 9.3 3.6 0.1 1.9 1 1 1 2 2 2 0 Prominin DUF605 PF04652.11 KFH45326.1 - 4.3 6.6 20.1 5 6.4 14.0 1.0 1 0 0 1 1 1 0 Vta1 like NUC153 PF08159.7 KFH45328.1 - 4e-13 48.6 2.1 4e-13 48.6 1.4 3.5 3 1 0 3 3 3 2 NUC153 domain DSPc PF00782.15 KFH45329.1 - 6.8e-11 41.8 0.0 1.4e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFH45329.1 - 0.00065 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KFH45329.1 - 0.021 15.1 0.0 0.057 13.6 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family MAD PF05557.8 KFH45330.1 - 6.3e-57 193.1 57.9 7.8e-57 192.8 40.1 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein GAS PF13851.1 KFH45330.1 - 0.9 8.6 81.5 0.28 10.3 7.7 5.4 4 2 1 5 5 5 0 Growth-arrest specific micro-tubule binding HALZ PF02183.13 KFH45330.1 - 4.4 7.0 36.8 0.65 9.7 0.7 8.2 9 0 0 9 9 9 0 Homeobox associated leucine zipper Sad1_UNC PF07738.8 KFH45331.1 - 3.9e-06 26.7 0.0 0.00092 19.0 0.0 2.4 1 1 0 2 2 2 2 Sad1 / UNC-like C-terminal DUF445 PF04286.7 KFH45331.1 - 0.0048 16.4 0.4 0.0048 16.4 0.3 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF445) PROCN PF08083.6 KFH45331.1 - 0.23 9.8 0.0 0.36 9.2 0.0 1.2 1 0 0 1 1 1 0 PROCN (NUC071) domain HD_3 PF13023.1 KFH45332.1 - 4.9e-47 159.7 0.0 6.5e-47 159.3 0.0 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.2 KFH45332.1 - 0.014 15.1 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme SWIRM PF04433.12 KFH45333.1 - 1.9e-13 50.3 0.0 7.8e-13 48.3 0.0 2.1 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 KFH45333.1 - 7.1e-09 35.0 5.5 1.3e-08 34.2 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 KFH45333.1 - 2.5e-07 30.6 0.1 9.9e-07 28.7 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFH45333.1 - 1e-05 25.5 0.0 2.7e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain ECH PF00378.15 KFH45334.1 - 1.1e-48 165.4 0.0 1.5e-48 165.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ADH_zinc_N PF00107.21 KFH45335.1 - 2e-29 101.7 1.0 3.9e-29 100.8 0.1 1.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFH45335.1 - 9.2e-17 62.1 0.0 2e-16 61.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFH45335.1 - 3.8e-11 42.7 0.0 7.9e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ApbA PF02558.11 KFH45335.1 - 0.053 12.9 0.1 0.2 11.0 0.1 1.9 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 KFH45335.1 - 0.056 13.4 0.2 0.12 12.3 0.2 1.5 1 0 0 1 1 1 0 NADH(P)-binding Methyltransf_18 PF12847.2 KFH45335.1 - 0.12 12.9 0.1 0.25 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 KFH45335.1 - 0.31 10.9 2.5 0.49 10.2 0.6 2.1 3 0 0 3 3 3 0 short chain dehydrogenase CoA_binding PF02629.14 KFH45336.1 - 3.3e-26 91.6 2.9 2.6e-25 88.7 0.1 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 KFH45336.1 - 4.2e-25 88.1 0.7 6e-25 87.6 0.5 1.2 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 KFH45336.1 - 7.2e-09 35.3 0.1 1.2e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 KFH45336.1 - 0.011 15.9 0.4 0.044 13.9 0.0 2.1 2 1 0 2 2 2 0 CoA binding domain FBPase_glpX PF03320.8 KFH45336.1 - 0.042 12.5 0.1 6.1 5.3 0.1 2.1 2 0 0 2 2 2 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded Cutinase PF01083.17 KFH45337.1 - 4e-26 91.8 0.0 9.2e-26 90.6 0.0 1.6 2 0 0 2 2 2 1 Cutinase C8 PF08742.6 KFH45337.1 - 0.00075 19.7 0.1 0.0015 18.7 0.0 1.5 1 0 0 1 1 1 1 C8 domain Prefoldin PF02996.12 KFH45337.1 - 0.019 14.5 0.2 0.039 13.6 0.2 1.4 1 0 0 1 1 1 0 Prefoldin subunit FlxA PF14282.1 KFH45337.1 - 0.02 14.8 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 FlxA-like protein PE-PPE PF08237.6 KFH45337.1 - 0.02 14.3 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain Phage_GP20 PF06810.6 KFH45337.1 - 0.023 14.1 0.1 0.038 13.4 0.1 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Abhydrolase_9 PF10081.4 KFH45337.1 - 0.027 13.1 0.0 0.043 12.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family DUF2580 PF10824.3 KFH45337.1 - 0.28 11.5 5.1 0.13 12.5 0.7 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2580) DUF2838 PF10998.3 KFH45338.1 - 0.024 14.5 0.0 0.86 9.5 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2838) MFS_1 PF07690.11 KFH45339.1 - 6.6e-09 34.9 27.5 6.6e-09 34.9 19.0 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 KFH45339.1 - 2e-07 30.6 2.6 2e-07 30.6 1.8 2.0 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 YqzM PF14141.1 KFH45339.1 - 0.063 13.0 0.2 12 5.7 0.0 2.9 2 0 0 2 2 2 0 YqzM-like protein Sulfatase PF00884.18 KFH45341.1 - 2e-57 194.7 1.5 2.5e-57 194.4 1.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KFH45341.1 - 0.055 12.7 1.4 0.12 11.7 1.0 1.8 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KFH45341.1 - 0.11 10.8 0.4 0.3 9.4 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF229) MFS_1 PF07690.11 KFH45343.1 - 3.4e-39 134.5 51.2 1.1e-32 113.1 18.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH45343.1 - 2e-09 36.5 8.9 2e-09 36.5 6.1 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 KFH45343.1 - 7.1e-07 27.9 20.2 0.0015 16.9 4.2 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 KFH45343.1 - 0.0013 18.4 0.7 0.0047 16.6 0.1 2.3 2 0 0 2 2 2 1 MFS_1 like family MFS_3 PF05977.8 KFH45343.1 - 0.25 9.4 9.0 0.005 15.0 1.2 1.8 2 0 0 2 2 2 0 Transmembrane secretion effector DUF500 PF04366.7 KFH45344.1 - 3.1e-38 130.0 0.1 8.1e-38 128.7 0.1 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF500) DUF924 PF06041.6 KFH45345.1 - 3.1e-53 180.3 0.0 7.5e-53 179.0 0.0 1.6 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Thioesterase PF00975.15 KFH45346.1 - 2.6e-18 67.0 0.0 6.3e-18 65.8 0.0 1.5 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 KFH45346.1 - 8.1e-08 32.4 0.6 9.5e-08 32.1 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH45346.1 - 0.00046 19.9 0.0 0.00057 19.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KFH45346.1 - 0.00094 18.8 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold SNF2_N PF00176.18 KFH45347.1 - 1.9e-71 240.3 1.7 3.4e-71 239.5 1.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 KFH45347.1 - 6.3e-50 168.8 16.6 6.3e-50 168.8 11.5 4.3 5 0 0 5 5 5 1 DNA-binding domain Helicase_C PF00271.26 KFH45347.1 - 7.9e-16 57.6 0.0 1.7e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ribosomal_S7e PF01251.13 KFH45348.1 - 3.2e-83 277.8 0.7 3.6e-83 277.7 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e ABC2_membrane PF01061.19 KFH45349.1 - 7.5e-88 293.1 66.9 1.8e-45 154.6 17.6 3.5 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 KFH45349.1 - 3.3e-34 118.1 0.0 1e-17 64.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KFH45349.1 - 3.2e-33 113.4 11.3 1.3e-29 101.8 0.0 3.0 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 KFH45349.1 - 7.5e-18 64.4 0.0 2.2e-17 62.8 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KFH45349.1 - 3.2e-07 29.9 0.1 0.00033 20.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KFH45349.1 - 7e-06 26.1 0.3 0.00081 19.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain ABC2_membrane_3 PF12698.2 KFH45349.1 - 1e-05 24.7 54.1 0.0035 16.4 19.1 3.4 2 2 0 2 2 2 2 ABC-2 family transporter protein DUF258 PF03193.11 KFH45349.1 - 2.7e-05 23.4 0.0 0.0029 16.7 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 KFH45349.1 - 4.5e-05 23.3 0.1 0.0028 17.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KFH45349.1 - 6.5e-05 22.3 0.4 0.02 14.4 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 KFH45349.1 - 0.00036 20.0 2.8 0.0024 17.3 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 KFH45349.1 - 0.0049 17.0 0.0 0.57 10.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KFH45349.1 - 0.017 14.7 0.5 2.3 7.8 0.2 2.7 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 KFH45349.1 - 0.025 14.8 0.0 0.37 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KFH45349.1 - 0.038 13.7 0.6 11 5.8 0.3 2.9 2 0 0 2 2 2 0 Part of AAA domain AAA_17 PF13207.1 KFH45349.1 - 0.068 13.9 0.0 1.2 10.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KFH45349.1 - 0.07 13.4 0.2 0.43 10.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 KFH45349.1 - 0.12 12.2 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 KFH45349.1 - 0.13 11.5 0.0 1.4 8.0 0.0 2.5 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain Peptidase_C39_2 PF13529.1 KFH45349.1 - 0.17 12.2 0.0 13 6.0 0.0 2.5 2 0 0 2 2 2 0 Peptidase_C39 like family MMR_HSR1 PF01926.18 KFH45349.1 - 0.19 11.6 0.0 22 5.0 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_10 PF12846.2 KFH45349.1 - 0.25 10.7 1.4 16 4.8 0.0 2.9 3 0 0 3 3 3 0 AAA-like domain UPF0079 PF02367.12 KFH45349.1 - 0.32 10.6 1.0 1.7 8.3 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Pkinase PF00069.20 KFH45350.1 - 0.0003 20.0 0.0 0.00044 19.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KFH45350.1 - 0.0024 17.6 0.3 0.01 15.5 0.0 2.1 3 0 0 3 3 3 1 Phosphotransferase enzyme family SR-25 PF10500.4 KFH45350.1 - 2.6 7.4 9.8 3.9 6.8 6.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein UPF0052 PF01933.13 KFH45351.1 - 1.2e-54 185.6 0.0 1.5e-54 185.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 RNase_T PF00929.19 KFH45353.1 - 0.00049 20.4 0.1 0.0021 18.3 0.0 1.8 1 1 1 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.15 KFH45353.1 - 0.055 12.9 0.0 0.091 12.2 0.0 1.4 1 0 0 1 1 1 0 3'-5' exonuclease MFS_1 PF07690.11 KFH45354.1 - 4e-37 127.7 51.8 3e-36 124.8 33.7 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KFH45354.1 - 2.5e-10 39.2 30.5 3.5e-10 38.7 21.2 1.2 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Cofilin_ADF PF00241.15 KFH45355.1 - 5.4e-24 84.4 0.0 1.1e-11 44.7 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein P3A PF08727.6 KFH45355.1 - 0.04 13.2 0.2 0.083 12.2 0.1 1.4 1 0 0 1 1 1 0 Poliovirus 3A protein like PAP2 PF01569.16 KFH45356.1 - 4.9e-17 61.8 4.4 4.9e-17 61.8 3.0 1.6 2 0 0 2 2 2 1 PAP2 superfamily AMP-binding PF00501.23 KFH45357.1 - 0 1123.7 0.0 6.6e-88 294.8 0.0 4.3 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 KFH45357.1 - 1.2e-172 572.6 0.0 1.1e-47 162.3 0.0 5.4 5 0 0 5 5 5 4 Condensation domain PP-binding PF00550.20 KFH45357.1 - 3e-49 165.1 1.8 5.2e-13 49.0 0.0 5.7 5 0 0 5 5 5 4 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KFH45357.1 - 1.7e-13 51.3 6.2 0.00019 22.3 0.0 5.8 5 1 0 5 5 5 3 AMP-binding enzyme C-terminal domain AATase PF07247.7 KFH45357.1 - 0.36 9.3 0.3 5.3 5.4 0.0 2.6 3 0 0 3 3 3 0 Alcohol acetyltransferase UPF0128 PF03673.8 KFH45357.1 - 2.7 7.2 0.0 6.7 5.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0128) AAA PF00004.24 KFH45359.1 - 4.5e-41 140.1 0.0 8.1e-41 139.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFH45359.1 - 1e-06 28.9 0.1 0.0003 20.9 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KFH45359.1 - 2.7e-06 27.3 0.0 5.9e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KFH45359.1 - 1.3e-05 24.2 0.0 2.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 KFH45359.1 - 8.2e-05 22.3 0.1 0.00033 20.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KFH45359.1 - 0.00017 21.6 0.5 0.0012 18.8 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 KFH45359.1 - 0.00037 19.6 0.0 0.0007 18.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KFH45359.1 - 0.00099 19.1 0.2 0.0046 16.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KFH45359.1 - 0.0038 17.1 0.0 0.0071 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFH45359.1 - 0.0056 17.5 0.7 0.013 16.3 0.1 2.0 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KFH45359.1 - 0.0062 16.2 0.3 0.016 14.9 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KFH45359.1 - 0.0077 15.6 0.1 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.7 KFH45359.1 - 0.0099 15.5 0.1 0.33 10.5 0.0 2.7 2 1 1 3 3 3 1 NACHT domain Zeta_toxin PF06414.7 KFH45359.1 - 0.01 14.9 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 KFH45359.1 - 0.011 15.6 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KFH45359.1 - 0.011 16.0 0.0 0.029 14.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KFH45359.1 - 0.013 15.1 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 KFH45359.1 - 0.014 14.1 0.1 0.038 12.7 0.0 1.7 2 0 0 2 2 2 0 TIP49 C-terminus PhoH PF02562.11 KFH45359.1 - 0.018 14.2 1.9 0.2 10.8 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.17 KFH45359.1 - 0.044 13.9 0.0 0.084 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 KFH45359.1 - 0.047 13.2 0.2 0.14 11.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KFH45359.1 - 0.047 12.5 0.0 0.075 11.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Mg_chelatase PF01078.16 KFH45359.1 - 0.052 12.6 0.1 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 KFH45359.1 - 0.058 12.4 0.1 0.44 9.6 0.1 2.1 1 1 1 2 2 2 0 KaiC AAA_25 PF13481.1 KFH45359.1 - 0.098 12.0 3.3 0.19 11.1 0.2 2.5 2 1 1 3 3 3 0 AAA domain DUF2075 PF09848.4 KFH45359.1 - 0.13 11.1 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CtIP_N PF10482.4 KFH45359.1 - 0.33 10.7 3.3 0.33 10.7 0.2 2.2 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain MASE1 PF05231.9 KFH45360.1 - 0.021 13.8 3.0 0.023 13.7 2.1 1.0 1 0 0 1 1 1 0 MASE1 UPF0233 PF06781.7 KFH45360.1 - 0.6 9.7 5.2 0.55 9.8 3.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0233) DUF3262 PF11660.3 KFH45360.1 - 3.4 7.8 9.7 78 3.4 6.8 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3262) FAP PF07174.6 KFH45361.1 - 0.011 15.1 2.4 0.011 14.9 1.7 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) zf-FPG_IleRS PF06827.9 KFH45361.1 - 0.05 13.2 0.4 0.05 13.2 0.3 2.1 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Mito_carr PF00153.22 KFH45362.1 - 9.4e-16 57.3 1.2 1.4e-09 37.5 0.0 3.3 2 1 0 2 2 2 2 Mitochondrial carrier protein FYVE PF01363.16 KFH45363.1 - 0.0028 17.5 9.1 0.0035 17.2 6.3 1.1 1 0 0 1 1 1 1 FYVE zinc finger zf-H2C2_2 PF13465.1 KFH45363.1 - 0.0072 16.5 0.7 0.0072 16.5 0.5 2.4 2 1 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFH45363.1 - 0.042 14.1 2.7 0.042 14.1 1.8 2.1 2 1 0 2 2 2 0 C2H2-type zinc finger VSP PF03302.8 KFH45363.1 - 0.082 11.5 3.4 0.081 11.5 2.4 1.0 1 0 0 1 1 1 0 Giardia variant-specific surface protein zf-met PF12874.2 KFH45363.1 - 0.093 12.9 3.4 0.25 11.5 2.4 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Coronavirus_5 PF05528.6 KFH45363.1 - 0.29 10.9 2.1 0.43 10.4 0.2 2.1 1 1 1 2 2 2 0 Coronavirus gene 5 protein DUF2225 PF09986.4 KFH45363.1 - 0.75 9.2 3.1 0.4 10.1 1.3 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) Cytochrome_C7 PF14522.1 KFH45363.1 - 0.88 9.2 14.6 1.6 8.4 10.1 1.5 1 1 0 1 1 1 0 Cytochrome c7 zf-C2H2 PF00096.21 KFH45363.1 - 3.6 8.1 9.6 0.38 11.1 2.8 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C3HC4_3 PF13920.1 KFH45363.1 - 6.6 6.4 10.9 2.4 7.9 0.4 2.7 1 1 2 3 3 3 0 Zinc finger, C3HC4 type (RING finger) ketoacyl-synt PF00109.21 KFH45364.1 - 1.6e-75 253.8 0.1 4.4e-75 252.4 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.23 KFH45364.1 - 2.8e-75 253.3 0.1 6.3e-75 252.1 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme Acyl_transf_1 PF00698.16 KFH45364.1 - 2.1e-61 208.0 0.0 4e-61 207.0 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KFH45364.1 - 1.4e-54 184.4 1.2 1.4e-54 184.4 0.8 3.2 4 0 0 4 4 4 1 KR domain Condensation PF00668.15 KFH45364.1 - 3.8e-48 163.8 0.1 6.1e-48 163.2 0.0 1.2 1 0 0 1 1 1 1 Condensation domain adh_short PF00106.20 KFH45364.1 - 2.1e-46 157.9 8.8 4.8e-46 156.7 0.8 4.1 4 0 0 4 4 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KFH45364.1 - 1.3e-39 134.7 2.8 2.1e-39 134.0 0.7 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 KFH45364.1 - 4.4e-23 81.4 0.0 5.9e-22 77.8 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.20 KFH45364.1 - 1.9e-19 69.6 0.1 5.5e-11 42.5 0.1 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 KFH45364.1 - 6.2e-12 45.6 1.2 1.4e-11 44.5 0.3 2.1 2 0 0 2 2 2 1 HxxPF-repeated domain Thiolase_N PF00108.18 KFH45364.1 - 0.037 13.0 0.1 0.073 12.0 0.0 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain DNA_gyraseB_C PF00986.16 KFH45364.1 - 0.63 9.8 0.0 1.7 8.4 0.0 1.7 1 0 0 1 1 1 0 DNA gyrase B subunit, carboxyl terminus 3Beta_HSD PF01073.14 KFH45364.1 - 1.1 7.9 0.0 2.2 6.9 0.0 1.5 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF2945 PF11160.3 KFH45366.1 - 6.5e-22 77.1 0.1 8.4e-22 76.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2945) UQ_con PF00179.21 KFH45367.1 - 9.1e-42 141.8 0.0 1.8e-41 140.8 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFH45367.1 - 1.1e-08 34.8 0.0 1.7e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UBA_3 PF09288.5 KFH45367.1 - 0.0089 15.6 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Chitin_bind_3 PF03067.10 KFH45368.1 - 3.9e-09 37.0 0.0 6.3e-07 29.8 0.0 2.2 1 1 0 1 1 1 1 Chitin binding domain TcdB_N PF12918.2 KFH45370.1 - 0.19 11.8 0.6 0.27 11.3 0.1 1.5 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain adh_short PF00106.20 KFH45371.1 - 8.7e-29 100.5 0.4 8.7e-29 100.5 0.3 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KFH45371.1 - 5.8e-15 55.4 0.2 1.1e-14 54.5 0.2 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFH45371.1 - 7.1e-08 32.5 0.0 1.1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase CopC PF04234.7 KFH45371.1 - 0.022 15.3 0.0 3.5 8.3 0.0 2.7 2 0 0 2 2 2 0 CopC domain Eno-Rase_NADH_b PF12242.3 KFH45371.1 - 0.052 13.3 0.3 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KFH45371.1 - 0.067 12.6 0.1 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFH45371.1 - 0.082 12.9 0.1 0.23 11.4 0.0 1.7 1 1 0 1 1 1 0 NADH(P)-binding p450 PF00067.17 KFH45372.1 - 4.4e-63 213.4 0.0 5.6e-63 213.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3185 PF11381.3 KFH45373.1 - 0.079 12.7 0.2 3.3 7.5 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) DUF4419 PF14388.1 KFH45374.1 - 2.1e-94 316.1 0.0 2.7e-94 315.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) EBP PF05241.7 KFH45375.1 - 0.31 10.0 5.5 0.58 9.1 3.3 1.9 1 1 0 1 1 1 0 Emopamil binding protein ATP-grasp_4 PF13535.1 KFH45378.1 - 1.7e-09 37.6 0.0 3.8e-09 36.5 0.0 1.5 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KFH45378.1 - 1.6e-06 28.0 0.0 2.7e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KFH45378.1 - 0.051 12.3 0.0 2.8 6.6 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon GMC_oxred_N PF00732.14 KFH45380.1 - 2.7e-49 167.9 0.0 3.5e-49 167.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFH45380.1 - 1.6e-33 116.0 0.0 2.4e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KFH45380.1 - 3.3e-06 27.0 0.5 3.4e-05 23.7 0.1 2.8 3 1 1 4 4 4 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFH45380.1 - 1.1e-05 24.4 5.0 0.0021 17.0 3.5 2.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KFH45380.1 - 2.7e-05 23.2 0.0 0.00087 18.3 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 KFH45380.1 - 0.00026 21.3 0.1 0.15 12.4 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFH45380.1 - 0.002 18.2 0.0 0.53 10.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFH45380.1 - 0.0027 17.6 0.0 0.088 12.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFH45380.1 - 0.0053 15.6 0.2 0.035 12.9 0.0 2.2 3 0 0 3 3 3 1 FAD binding domain Trp_halogenase PF04820.9 KFH45380.1 - 0.032 12.8 0.1 0.074 11.6 0.0 1.6 2 0 0 2 2 2 0 Tryptophan halogenase Dynactin_p62 PF05502.8 KFH45381.1 - 7.1e-154 513.1 0.0 8.9e-154 512.8 0.0 1.1 1 0 0 1 1 1 1 Dynactin p62 family p450 PF00067.17 KFH45382.1 - 7.8e-69 232.3 0.0 1e-68 231.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABC_tran PF00005.22 KFH45384.1 - 2.7e-45 154.0 0.0 1.7e-22 80.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KFH45384.1 - 1.1e-20 74.7 0.2 8.5e-05 22.6 0.0 4.3 3 1 0 4 4 4 4 AAA domain ABC_tran_2 PF12848.2 KFH45384.1 - 4.3e-19 68.1 0.6 4.3e-19 68.1 0.4 2.7 3 0 0 3 3 2 1 ABC transporter SMC_N PF02463.14 KFH45384.1 - 1.5e-10 40.7 0.2 0.0013 18.0 0.1 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KFH45384.1 - 4.7e-08 32.4 0.5 0.00091 18.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KFH45384.1 - 1.5e-07 31.9 2.3 0.038 14.3 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_17 PF13207.1 KFH45384.1 - 2.2e-06 28.4 0.3 0.032 15.0 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 KFH45384.1 - 9.2e-06 25.8 0.1 0.25 11.4 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KFH45384.1 - 1.5e-05 25.2 0.0 0.044 14.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 KFH45384.1 - 1.8e-05 24.4 0.1 0.13 11.8 0.0 2.7 2 0 0 2 2 2 2 NACHT domain DUF258 PF03193.11 KFH45384.1 - 1.9e-05 23.9 0.0 0.0043 16.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 KFH45384.1 - 2e-05 25.0 0.0 0.048 14.1 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA PF00004.24 KFH45384.1 - 3.3e-05 24.0 0.0 0.38 10.9 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KFH45384.1 - 3.5e-05 23.7 0.0 0.37 10.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.1 KFH45384.1 - 0.0001 21.7 0.0 0.27 10.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 KFH45384.1 - 0.00016 21.5 0.3 0.099 12.6 0.1 3.1 3 1 0 3 3 3 1 50S ribosome-binding GTPase AAA_5 PF07728.9 KFH45384.1 - 0.00027 20.6 0.2 1.1 8.9 0.1 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_15 PF13175.1 KFH45384.1 - 0.00035 19.7 0.0 3.4 6.6 0.0 3.8 4 0 0 4 4 4 1 AAA ATPase domain RNA_helicase PF00910.17 KFH45384.1 - 0.00036 20.6 0.9 1 9.5 0.0 3.0 3 0 0 3 3 2 2 RNA helicase AAA_10 PF12846.2 KFH45384.1 - 0.00062 19.3 1.4 0.44 9.9 0.2 2.7 3 0 0 3 3 2 2 AAA-like domain SbcCD_C PF13558.1 KFH45384.1 - 0.00063 19.6 0.6 0.58 10.1 0.1 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 KFH45384.1 - 0.00064 19.7 2.9 0.2 11.6 0.1 3.4 2 2 1 3 3 3 1 AAA ATPase domain Dynamin_N PF00350.18 KFH45384.1 - 0.00082 19.2 0.2 1.4 8.7 0.0 3.3 4 0 0 4 4 3 1 Dynamin family MobB PF03205.9 KFH45384.1 - 0.0013 18.4 0.2 0.051 13.2 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 KFH45384.1 - 0.0015 18.5 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KFH45384.1 - 0.0021 17.9 0.0 2.1 8.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KFH45384.1 - 0.0029 17.3 0.0 1.4 8.5 0.0 2.6 2 0 0 2 2 2 1 Archaeal ATPase ATP-synt_ab PF00006.20 KFH45384.1 - 0.011 15.2 0.0 1 8.7 0.0 3.0 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain MCM PF00493.18 KFH45384.1 - 0.02 13.7 0.1 2.4 6.8 0.0 2.3 2 0 0 2 2 2 0 MCM2/3/5 family VirE PF05272.6 KFH45384.1 - 0.024 14.1 0.1 5.1 6.5 0.0 2.9 3 0 0 3 3 3 0 Virulence-associated protein E DAP3 PF10236.4 KFH45384.1 - 0.036 12.9 0.1 6.4 5.6 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 NB-ARC PF00931.17 KFH45384.1 - 0.052 12.3 0.0 5.9 5.6 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain DUF87 PF01935.12 KFH45384.1 - 0.066 13.0 0.2 14 5.4 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 NTPase_1 PF03266.10 KFH45384.1 - 0.072 12.7 0.3 4.8 6.8 0.2 2.6 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.1 KFH45384.1 - 0.096 12.2 0.9 10 5.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain GFA PF04828.9 KFH45385.1 - 5.3e-09 35.8 0.6 5.3e-09 35.8 0.4 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Lar_restr_allev PF14354.1 KFH45385.1 - 0.0071 16.6 4.1 0.5 10.6 0.4 2.3 1 1 1 2 2 2 2 Restriction alleviation protein Lar Glyco_hydro_72 PF03198.9 KFH45386.1 - 4.6e-119 397.0 2.5 5.9e-119 396.7 1.7 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 KFH45386.1 - 7e-23 80.9 1.6 2.1e-22 79.4 1.1 1.9 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.12 KFH45386.1 - 1.7e-08 33.7 0.2 3e-08 32.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 KFH45386.1 - 0.00021 20.5 0.4 0.0053 15.9 0.3 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Mito_carr PF00153.22 KFH45387.1 - 4.2e-71 234.7 2.5 3.2e-23 81.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein p450 PF00067.17 KFH45388.1 - 4.7e-50 170.4 0.0 6.1e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Amidohydro_1 PF01979.15 KFH45389.1 - 1.7e-35 123.2 0.0 2.6e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KFH45389.1 - 4.1e-09 36.1 1.6 4.8e-07 29.3 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_4 PF13147.1 KFH45389.1 - 5.9e-09 36.3 1.3 1.5e-05 25.2 0.1 2.5 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 KFH45389.1 - 0.00026 20.7 2.1 0.00042 20.0 0.2 2.3 1 1 1 2 2 2 1 Amidohydrolase A_deaminase PF00962.17 KFH45389.1 - 0.069 12.0 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Adenosine/AMP deaminase Bcl-2_3 PF15286.1 KFH45390.1 - 0.076 13.4 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like Op_neuropeptide PF08035.6 KFH45390.1 - 0.14 11.7 0.0 0.33 10.5 0.0 1.6 1 0 0 1 1 1 0 Opioids neuropeptide YopE_N PF09020.5 KFH45391.1 - 0.35 10.9 2.1 0.29 11.1 0.6 1.5 2 0 0 2 2 2 0 YopE, N terminal ADH_zinc_N PF00107.21 KFH45392.1 - 1.7e-30 105.2 0.1 2.9e-30 104.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFH45392.1 - 2e-16 61.0 0.0 1.3e-15 58.4 0.0 2.2 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFH45392.1 - 7.6e-09 35.3 0.1 1.5e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 KFH45392.1 - 0.0022 18.0 0.0 0.0045 16.9 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Acyl_transf_1 PF00698.16 KFH45393.1 - 2.8e-68 230.6 0.8 5.6e-68 229.6 0.6 1.5 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 KFH45393.1 - 2.6e-65 220.4 0.1 3.1e-64 216.8 0.0 2.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 KFH45393.1 - 2.6e-56 190.9 0.0 4.9e-56 190.0 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 KFH45393.1 - 2.5e-55 186.9 2.9 9.4e-55 185.0 2.0 2.0 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KFH45393.1 - 3e-43 147.6 1.4 1.6e-42 145.2 1.0 2.4 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KFH45393.1 - 1.2e-32 112.2 0.2 3.3e-32 110.8 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KFH45393.1 - 4.6e-19 68.7 0.0 1.7e-18 66.9 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KFH45393.1 - 6.9e-16 57.9 0.1 1.9e-15 56.5 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFH45393.1 - 1.7e-12 48.3 0.0 8.3e-12 46.1 0.0 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KFH45393.1 - 8.3e-11 41.8 0.0 3.2e-10 39.9 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH45393.1 - 6.8e-10 38.7 0.0 1.6e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KFH45393.1 - 1.7e-09 37.7 0.2 5.9e-09 36.0 0.1 2.0 2 0 0 2 2 1 1 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 KFH45393.1 - 3.5e-08 33.9 0.0 1.1e-07 32.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH45393.1 - 1e-07 32.3 0.0 2.5e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 KFH45393.1 - 1.9e-06 27.5 0.2 7.1e-06 25.7 0.1 2.1 2 0 0 2 2 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_25 PF13649.1 KFH45393.1 - 3e-06 27.5 0.0 8.5e-06 26.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 KFH45393.1 - 1.5e-05 24.1 0.3 0.0018 17.2 0.0 2.3 2 0 0 2 2 2 1 Thiolase, N-terminal domain NodS PF05401.6 KFH45393.1 - 3.7e-05 23.2 0.0 7.2e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.13 KFH45393.1 - 0.00027 20.1 0.0 0.00053 19.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.12 KFH45393.1 - 0.0031 16.9 0.0 0.0058 16.0 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase ACP_syn_III PF08545.5 KFH45393.1 - 0.0033 17.0 0.2 0.0085 15.7 0.2 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_16 PF10294.4 KFH45393.1 - 0.017 14.5 0.0 0.044 13.2 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase RrnaAD PF00398.15 KFH45393.1 - 0.36 9.8 0.0 0.65 8.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DREV PF05219.7 KFH45393.1 - 0.41 9.4 0.0 0.84 8.4 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase zf-UDP PF14569.1 KFH45394.1 - 0.66 9.7 4.1 1.2 8.9 2.8 1.4 1 1 0 1 1 1 0 Zinc-binding RING-finger MFS_1 PF07690.11 KFH45395.1 - 5.6e-25 87.7 28.1 5.6e-25 87.7 19.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 KFH45396.1 - 1.8e-10 39.9 1.0 2.2e-07 29.8 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH45396.1 - 8.7e-06 25.5 8.9 1.4e-05 24.8 6.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APH PF01636.18 KFH45397.1 - 4.9e-13 49.3 0.0 1.1e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF2706 PF10913.3 KFH45397.1 - 0.19 11.3 0.3 7.1 6.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2706) Chromo_shadow PF01393.14 KFH45398.1 - 6.5e-13 48.3 0.3 2.9e-11 43.0 0.0 2.3 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.19 KFH45398.1 - 4.3e-11 42.3 6.0 9.2e-11 41.2 0.7 2.7 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain AT_hook PF02178.14 KFH45398.1 - 0.12 12.0 5.0 0.5 10.1 3.5 2.1 1 0 0 1 1 1 0 AT hook motif ABC1 PF03109.11 KFH45399.1 - 1.2e-24 86.5 0.0 2.1e-15 56.7 0.0 2.7 1 1 1 2 2 2 2 ABC1 family APH PF01636.18 KFH45399.1 - 0.019 14.6 0.0 0.046 13.4 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF2204 PF09970.4 KFH45401.1 - 0.00016 21.2 0.0 0.0002 20.9 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF2204) UQ_con PF00179.21 KFH45402.1 - 1.5e-26 92.4 0.1 2.1e-26 92.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Response_reg PF00072.19 KFH45403.1 - 2.2e-16 59.8 0.0 5.1e-16 58.6 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KFH45403.1 - 1.3e-07 31.4 0.0 6.8e-07 29.1 0.0 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.21 KFH45403.1 - 0.042 13.5 0.0 0.094 12.4 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Spermine_synth PF01564.12 KFH45403.1 - 0.2 10.5 0.0 0.35 9.7 0.0 1.3 1 0 0 1 1 1 0 Spermine/spermidine synthase FliE PF02049.13 KFH45403.1 - 0.22 11.5 1.6 1.7 8.7 0.0 3.2 3 1 1 4 4 4 0 Flagellar hook-basal body complex protein FliE RRM_5 PF13893.1 KFH45404.1 - 0.0064 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 KFH45404.1 - 0.034 13.8 0.0 0.072 12.7 0.0 1.6 1 0 0 1 1 1 0 DbpA RNA binding domain Cast PF10174.4 KFH45405.1 - 0.042 11.9 5.0 0.27 9.2 0.8 2.1 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone Phage_lysis PF03245.8 KFH45405.1 - 0.33 10.9 5.1 0.11 12.4 0.4 2.3 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein DUF2216 PF10226.4 KFH45405.1 - 1.4 8.3 6.8 0.28 10.6 0.3 2.3 2 1 0 2 2 2 0 Uncharacterized conserved proteins (DUF2216) ATG16 PF08614.6 KFH45405.1 - 9.4 6.0 12.4 1.5 8.6 0.2 2.9 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Acetyltransf_1 PF00583.19 KFH45407.1 - 1.8e-06 27.9 0.0 2.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 KFH45407.1 - 0.00016 21.5 0.0 0.00025 20.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KFH45407.1 - 0.0007 19.7 0.0 0.0031 17.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFH45407.1 - 0.03 14.4 0.0 0.3 11.2 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KFH45407.1 - 0.031 14.2 0.0 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFH45407.1 - 0.037 13.7 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein SKG6 PF08693.5 KFH45408.1 - 0.0023 17.2 5.8 0.0044 16.2 4.0 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CFEM PF05730.6 KFH45408.1 - 0.16 11.7 18.2 0.46 10.3 2.2 3.3 3 0 0 3 3 3 0 CFEM domain DUF3188 PF11384.3 KFH45408.1 - 0.63 9.6 3.4 1.3 8.6 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) ABC2_membrane PF01061.19 KFH45409.1 - 2.9e-95 317.3 55.2 3.9e-50 169.9 16.2 3.4 4 0 0 4 4 3 2 ABC-2 type transporter PDR_CDR PF06422.7 KFH45409.1 - 1.9e-39 133.4 0.1 1.4e-34 117.8 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 KFH45409.1 - 1.4e-32 112.8 0.0 1.2e-16 61.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 KFH45409.1 - 2e-24 85.4 0.0 4e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_16 PF13191.1 KFH45409.1 - 2.9e-08 33.9 0.0 2.9e-06 27.3 0.1 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 KFH45409.1 - 2.9e-07 30.0 0.1 0.0015 17.9 0.1 2.8 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 KFH45409.1 - 1.8e-05 24.0 0.0 0.0011 18.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 KFH45409.1 - 2.7e-05 24.0 0.1 0.051 13.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain cobW PF02492.14 KFH45409.1 - 7.7e-05 22.2 0.3 0.002 17.5 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 KFH45409.1 - 8.2e-05 22.0 0.3 0.024 14.1 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KFH45409.1 - 0.00076 19.6 0.0 0.3 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 KFH45409.1 - 0.0011 18.1 16.9 0.0011 18.1 11.7 3.7 2 2 1 3 3 2 1 ABC-2 family transporter protein AAA_17 PF13207.1 KFH45409.1 - 0.0025 18.6 0.0 1.5 9.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KFH45409.1 - 0.0034 17.0 0.1 1.8 8.1 0.2 2.5 2 0 0 2 2 2 1 NACHT domain AAA_21 PF13304.1 KFH45409.1 - 0.0068 16.4 0.0 1.4 8.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KFH45409.1 - 0.0071 16.0 0.1 5 6.9 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 KFH45409.1 - 0.015 15.5 0.0 1.2 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KFH45409.1 - 0.036 14.2 0.1 6 7.0 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 KFH45409.1 - 0.041 13.4 0.2 3.7 7.1 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 KFH45409.1 - 0.072 13.0 0.0 0.67 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KFH45409.1 - 0.072 13.2 0.1 3.5 7.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase SMC_N PF02463.14 KFH45409.1 - 0.076 12.2 0.0 8.6 5.5 0.0 3.2 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain Miro PF08477.8 KFH45409.1 - 0.099 13.1 0.0 14 6.1 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_23 PF13476.1 KFH45409.1 - 0.15 12.3 0.0 0.53 10.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_10 PF12846.2 KFH45409.1 - 0.26 10.6 1.4 7.1 5.9 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain T2SE PF00437.15 KFH45409.1 - 0.3 9.9 0.0 3.1 6.6 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_15 PF13175.1 KFH45409.1 - 1.6 7.6 0.0 2.6 6.9 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Choline_kinase PF01633.15 KFH45410.1 - 0.13 11.7 0.0 0.28 10.7 0.0 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase adh_short PF00106.20 KFH45411.1 - 3.3e-27 95.4 0.3 4.3e-27 95.0 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH45411.1 - 5.3e-25 88.5 0.0 6.3e-25 88.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH45411.1 - 1.3e-11 44.5 0.1 1.8e-11 44.0 0.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFH45411.1 - 0.038 13.9 0.2 0.29 11.1 0.1 2.0 2 0 0 2 2 2 0 NADH(P)-binding Epimerase PF01370.16 KFH45411.1 - 0.073 12.4 0.2 0.28 10.5 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family dCMP_cyt_deam_1 PF00383.17 KFH45412.1 - 1.6e-11 43.7 0.1 2.2e-11 43.3 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APH PF01636.18 KFH45413.1 - 5.8e-07 29.4 0.0 5.3e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family HD PF01966.17 KFH45414.1 - 8.2e-07 29.0 0.2 1.4e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 HD domain INCA1 PF15142.1 KFH45414.1 - 0.14 11.8 0.0 1.2 8.9 0.0 2.0 2 0 0 2 2 2 0 INCA1 Stn1 PF10451.4 KFH45415.1 - 8e-12 44.5 2.6 1.4e-05 24.0 0.1 2.2 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.20 KFH45415.1 - 0.00031 20.5 0.1 0.014 15.2 0.0 2.3 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Pex14_N PF04695.8 KFH45415.1 - 8.2 6.4 9.7 2.8 8.0 1.8 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Na_Ca_ex PF01699.19 KFH45419.1 - 8.7e-46 155.0 31.0 5.2e-23 81.1 9.0 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Zn_clus PF00172.13 KFH45420.1 - 1.8e-09 37.3 8.7 3.2e-09 36.5 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFH45420.1 - 3.1e-06 26.2 0.0 5.7e-06 25.3 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Mito_carr PF00153.22 KFH45421.1 - 1.7e-55 184.6 4.7 8.8e-20 70.2 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein COX15-CtaA PF02628.10 KFH45422.1 - 6.1e-95 317.5 9.0 7.7e-95 317.2 6.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein PQ-loop PF04193.9 KFH45422.1 - 0.09 12.3 1.2 7.5 6.1 0.1 2.8 2 0 0 2 2 2 0 PQ loop repeat DUF3439 PF11921.3 KFH45422.1 - 0.22 11.3 6.5 0.54 10.0 4.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Glyco_hydro_67M PF07488.7 KFH45423.1 - 2e-151 503.5 0.0 2.6e-151 503.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.7 KFH45423.1 - 1.3e-89 299.4 2.0 2.1e-89 298.7 1.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.9 KFH45423.1 - 4.2e-28 97.8 0.0 7.5e-28 97.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.10 KFH45423.1 - 0.0012 19.4 0.1 0.0031 18.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 RRM_1 PF00076.17 KFH45424.1 - 1.2e-07 31.1 0.1 2.3e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH45424.1 - 4.2e-06 26.6 0.0 8.4e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFH45424.1 - 0.00052 19.7 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF1886 PF09171.5 KFH45424.1 - 0.066 12.2 0.1 0.1 11.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1886) DUF1680 PF07944.7 KFH45425.1 - 0.13 10.5 0.0 0.21 9.8 0.0 1.4 2 0 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) BUD22 PF09073.5 KFH45426.1 - 2.8e-82 277.1 28.4 3.3e-82 276.8 19.7 1.1 1 0 0 1 1 1 1 BUD22 CCDC-167 PF15188.1 KFH45426.1 - 0.052 13.5 2.0 0.45 10.5 0.7 2.7 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Nop14 PF04147.7 KFH45426.1 - 6.2 4.5 28.1 12 3.6 19.5 1.4 1 0 0 1 1 1 0 Nop14-like family ETX_MTX2 PF03318.8 KFH45427.1 - 0.0033 17.0 4.2 0.0065 16.0 2.9 1.5 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 FA_hydroxylase PF04116.8 KFH45428.1 - 4.9e-17 62.3 17.1 4.9e-17 62.3 11.9 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily PapC_C PF13953.1 KFH45428.1 - 0.15 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 PapC C-terminal domain ParA PF10609.4 KFH45429.1 - 3.9e-32 109.9 0.2 7.6e-32 109.0 0.2 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KFH45429.1 - 6e-15 55.1 0.1 8.4e-15 54.6 0.1 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KFH45429.1 - 1.9e-08 34.4 0.0 1.7e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 KFH45429.1 - 0.00022 20.4 0.0 0.00029 19.9 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.13 KFH45429.1 - 0.0011 18.2 0.0 0.12 11.5 0.0 2.3 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.1 KFH45429.1 - 0.0026 17.3 0.1 0.21 11.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 KFH45429.1 - 0.0034 16.4 0.3 0.043 12.8 0.1 2.2 2 0 0 2 2 2 1 Anion-transporting ATPase YhjQ PF06564.7 KFH45429.1 - 0.033 13.5 0.6 0.1 11.9 0.2 1.8 2 0 0 2 2 2 0 YhjQ protein AAA_25 PF13481.1 KFH45429.1 - 0.046 13.1 1.3 0.14 11.5 0.9 1.9 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KFH45429.1 - 0.13 11.9 1.5 4.3 7.1 0.1 2.8 2 0 0 2 2 2 0 Part of AAA domain Zn_Tnp_IS1595 PF12760.2 KFH45429.1 - 0.15 11.8 0.2 0.3 10.9 0.2 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Ribosomal_S27e PF01667.12 KFH45429.1 - 0.15 11.6 0.2 0.36 10.4 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein S27 Syntaxin-6_N PF09177.6 KFH45432.1 - 0.12 12.8 0.4 5.9 7.3 0.3 2.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Cyto_heme_lyase PF01265.12 KFH45433.1 - 3.2e-76 256.3 0.0 3.7e-76 256.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Fungal_trans PF04082.13 KFH45434.1 - 3.1e-16 59.0 0.3 6.1e-16 58.0 0.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH45434.1 - 1.2e-06 28.3 7.2 2.1e-06 27.4 5.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ASL_C2 PF14698.1 KFH45434.1 - 0.13 12.3 0.1 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Argininosuccinate lyase C-terminal Bac_surface_Ag PF01103.18 KFH45435.1 - 2.3e-35 122.6 0.1 2.9e-35 122.2 0.1 1.1 1 0 0 1 1 1 1 Surface antigen Peptidase_M28 PF04389.12 KFH45436.1 - 1.3e-30 106.4 0.0 2.3e-30 105.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KFH45436.1 - 5e-12 45.3 0.1 1e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 KFH45436.1 - 1.5e-06 27.8 0.0 2.6e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF2680 PF10925.3 KFH45436.1 - 0.029 14.2 0.1 0.061 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) HgmA PF04209.8 KFH45438.1 - 4.5e-174 578.8 0.0 5.2e-174 578.5 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Vint PF14623.1 KFH45439.1 - 4.3e-48 162.8 0.0 7.7e-48 162.0 0.0 1.4 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.1 KFH45439.1 - 8.8e-30 102.6 0.0 1.5e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA PF00092.23 KFH45439.1 - 8.6e-20 71.1 0.0 2.3e-19 69.8 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 KFH45439.1 - 6.3e-19 68.7 0.0 1.2e-18 67.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 KFH45439.1 - 2.2e-14 53.4 0.0 2e-12 47.0 0.0 2.7 3 0 0 3 3 3 1 von Willebrand factor type A domain Hint PF01079.15 KFH45439.1 - 0.2 10.8 0.0 0.53 9.4 0.0 1.6 1 0 0 1 1 1 0 Hint module LRR_4 PF12799.2 KFH45440.1 - 1.9e-30 103.9 41.2 3.4e-05 23.3 0.0 10.4 3 2 9 13 13 13 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFH45440.1 - 4.1e-27 93.7 36.3 2.7e-06 27.0 0.1 7.7 4 2 5 10 10 10 9 Leucine rich repeat LRR_1 PF00560.28 KFH45440.1 - 1.3e-13 48.9 37.6 0.2 11.8 0.1 14.7 15 2 1 16 16 16 3 Leucine Rich Repeat LRR_7 PF13504.1 KFH45440.1 - 4e-07 29.1 31.9 1.1 9.7 0.0 13.4 15 0 0 15 15 15 3 Leucine rich repeat LRR_6 PF13516.1 KFH45440.1 - 0.00014 21.5 25.5 3.6 7.9 0.0 10.5 12 1 1 13 13 13 2 Leucine Rich repeat LRR_9 PF14580.1 KFH45440.1 - 0.025 14.1 6.8 2.7 7.5 0.3 3.8 2 2 1 3 3 3 0 Leucine-rich repeat Aminotran_3 PF00202.16 KFH45441.1 - 4.5e-90 301.9 0.0 6e-90 301.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III HET PF06985.6 KFH45443.1 - 2.3e-29 102.3 2.9 3.6e-29 101.7 2.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3329 PF11808.3 KFH45443.1 - 0.039 14.0 0.7 0.1 12.6 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3329) APH PF01636.18 KFH45444.1 - 1.6e-15 57.4 0.1 3.4e-15 56.4 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family bPH_4 PF06713.6 KFH45444.1 - 0.00039 20.2 0.0 0.00066 19.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial PH domain Choline_kinase PF01633.15 KFH45444.1 - 0.0037 16.8 0.0 0.0064 16.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DnaJ PF00226.26 KFH45446.1 - 5e-24 83.8 3.9 5e-24 83.8 2.7 2.3 2 0 0 2 2 2 1 DnaJ domain PNPase PF03726.9 KFH45446.1 - 1 9.6 9.9 5.8 7.2 0.1 3.7 4 0 0 4 4 4 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain DUF2293 PF10056.4 KFH45447.1 - 3.9e-24 84.4 0.1 8.8e-24 83.3 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) Glyco_hydro_81 PF03639.8 KFH45449.1 - 1.7e-202 674.2 0.1 1.9e-202 674.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 CsbD PF05532.7 KFH45449.1 - 0.04 13.5 0.1 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 CsbD-like Gag_p10 PF02337.12 KFH45449.1 - 0.065 12.9 0.0 13 5.6 0.0 2.6 2 0 0 2 2 2 0 Retroviral GAG p10 protein DEC-1_N PF04625.8 KFH45450.1 - 6.1 5.4 15.9 9.1 4.8 11.0 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Utp14 PF04615.8 KFH45451.1 - 6.7e-168 560.1 69.9 6.7e-168 560.1 48.5 2.4 1 1 1 2 2 2 1 Utp14 protein Mlo PF03094.10 KFH45451.1 - 0.89 7.5 1.5 2 6.4 0.1 2.0 2 0 0 2 2 2 0 Mlo family adh_short PF00106.20 KFH45454.1 - 9.8e-22 77.6 0.3 1.5e-20 73.8 0.2 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH45454.1 - 1.1e-19 71.2 0.0 6.4e-19 68.6 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH45454.1 - 1.3e-09 37.9 0.1 1.1e-08 34.9 0.0 2.0 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 KFH45454.1 - 0.0046 17.0 0.1 0.0078 16.3 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 KFH45454.1 - 0.0054 15.7 0.1 0.0078 15.2 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 KFH45454.1 - 0.025 14.6 0.2 0.049 13.6 0.1 1.5 2 0 0 2 2 2 0 NADH(P)-binding 3Beta_HSD PF01073.14 KFH45454.1 - 0.033 12.9 0.0 0.047 12.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Pyr_redox PF00070.22 KFH45454.1 - 0.051 13.9 0.2 0.092 13.1 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.16 KFH45454.1 - 0.073 12.4 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family zf-Di19 PF05605.7 KFH45455.1 - 0.0094 16.0 0.1 0.023 14.8 0.0 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding HALZ PF02183.13 KFH45455.1 - 0.033 13.8 6.0 0.036 13.7 1.7 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF972 PF06156.8 KFH45455.1 - 0.045 14.1 0.3 0.045 14.1 0.2 2.5 4 0 0 4 4 4 0 Protein of unknown function (DUF972) zf-C2HC_2 PF13913.1 KFH45455.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-ribbon_3 PF13248.1 KFH45455.1 - 0.11 11.6 0.4 0.23 10.6 0.3 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-C2H2 PF00096.21 KFH45455.1 - 0.12 12.8 0.1 0.28 11.5 0.1 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type Fungal_trans PF04082.13 KFH45456.1 - 7.1e-13 48.0 0.1 1.3e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH45456.1 - 7e-05 22.6 10.9 0.00012 21.8 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Vac_ImportDeg PF09783.4 KFH45456.1 - 0.076 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Vacuolar import and degradation protein TRAUB PF08164.7 KFH45457.1 - 3.6e-30 103.8 2.8 4.1e-30 103.7 0.1 2.5 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 KFH45457.1 - 2.5e-29 102.0 0.6 2.5e-29 102.0 0.4 3.6 5 0 0 5 5 5 1 Apoptosis antagonizing transcription factor Use1 PF09753.4 KFH45457.1 - 0.16 11.3 6.0 0.47 9.8 4.1 1.7 1 0 0 1 1 1 0 Membrane fusion protein Use1 DUF4013 PF13197.1 KFH45459.1 - 0.0077 15.5 7.0 0.0088 15.3 4.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4013) MrpF_PhaF PF04066.8 KFH45459.1 - 2 8.7 6.2 10 6.4 0.4 2.4 2 0 0 2 2 2 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) LBR_tudor PF09465.5 KFH45460.1 - 0.017 14.7 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain DUF4537 PF15057.1 KFH45460.1 - 0.028 14.2 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) IL6 PF00489.12 KFH45460.1 - 0.04 13.5 0.1 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family Rad9_Rad53_bind PF08605.5 KFH45460.1 - 0.063 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Fungal Rad9-like Rad53-binding Med21 PF11221.3 KFH45460.1 - 0.1 12.5 0.2 0.1 12.5 0.1 2.2 3 1 0 3 3 3 0 Subunit 21 of Mediator complex SH3_1 PF00018.23 KFH45461.1 - 4.9e-09 35.4 0.0 8.9e-09 34.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFH45461.1 - 9e-09 34.7 0.1 1.8e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFH45461.1 - 4.5e-06 26.0 0.1 3.6e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain MARVEL PF01284.18 KFH45462.1 - 0.00014 21.6 25.6 0.0013 18.5 17.4 2.1 1 1 1 2 2 2 1 Membrane-associating domain PulG PF11773.3 KFH45462.1 - 0.24 11.1 0.9 4.3 7.1 0.0 2.9 3 0 0 3 3 3 0 Type II secretory pathway pseudopilin CD20 PF04103.10 KFH45462.1 - 0.48 10.3 17.1 0.16 11.9 10.0 1.6 2 0 0 2 2 2 0 CD20-like family FixP_N PF14715.1 KFH45462.1 - 0.68 9.3 4.7 1.7 8.0 3.2 1.7 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP NADHdh_A3 PF14987.1 KFH45462.1 - 1.9 8.4 4.6 5.6 6.9 3.2 1.8 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 DUF2593 PF10767.4 KFH45462.1 - 3.1 7.4 8.2 6.1 6.5 5.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2593) DUF1479 PF07350.7 KFH45463.1 - 2e-126 421.8 0.0 2.3e-126 421.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) DUF1658 PF07871.6 KFH45463.1 - 0.099 12.2 0.6 0.25 11.0 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1658) tRNA-synt_2c PF01411.14 KFH45464.1 - 5.6e-210 698.3 0.0 8.1e-210 697.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KFH45464.1 - 8e-18 64.0 0.1 3.1e-17 62.1 0.1 2.1 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 KFH45464.1 - 0.0079 15.8 0.5 0.021 14.4 0.4 1.8 1 0 0 1 1 1 1 DHHA1 domain TFIIS_M PF07500.9 KFH45465.1 - 1.1e-26 93.1 1.0 2.7e-26 91.8 0.7 1.7 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 KFH45465.1 - 1e-16 60.2 8.1 1.7e-16 59.5 5.6 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 KFH45465.1 - 4e-14 51.8 0.4 9.8e-14 50.6 0.3 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Hus1 PF04005.7 KFH45465.1 - 0.0088 15.0 0.5 0.015 14.3 0.4 1.3 1 0 0 1 1 1 1 Hus1-like protein Cytochrom_NNT PF03264.9 KFH45465.1 - 0.027 13.8 3.4 0.066 12.6 2.4 1.6 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region UCR_UQCRX_QCR9 PF05365.7 KFH45465.1 - 0.11 12.1 0.0 13 5.5 0.0 2.4 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Evr1_Alr PF04777.8 KFH45465.1 - 0.26 11.2 1.9 0.61 10.0 1.0 1.8 2 0 0 2 2 2 0 Erv1 / Alr family CDC37_N PF03234.9 KFH45465.1 - 0.34 11.2 6.6 0.066 13.5 0.4 2.4 2 1 1 3 3 3 0 Cdc37 N terminal kinase binding Sgf11 PF08209.6 KFH45465.1 - 1.6 8.0 6.7 1.2 8.4 1.3 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Dynein_light PF01221.13 KFH45466.1 - 1.5e-37 127.4 0.5 2.1e-37 126.9 0.4 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 Imm28 PF15574.1 KFH45466.1 - 0.048 13.2 0.1 0.063 12.8 0.1 1.2 1 0 0 1 1 1 0 Immunity protein 28 DUF2939 PF11159.3 KFH45466.1 - 0.082 13.0 0.4 0.11 12.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) GIT_SHD PF08518.6 KFH45467.1 - 1e-21 75.9 6.4 1e-13 50.3 0.5 2.5 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT DUF1843 PF08898.5 KFH45467.1 - 0.0012 18.8 0.5 0.0012 18.8 0.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1843) CENP-K PF11802.3 KFH45467.1 - 0.083 12.1 16.9 0.021 14.0 9.0 1.8 1 1 1 2 2 2 0 Centromere-associated protein K HAUS6_N PF14661.1 KFH45467.1 - 0.87 8.8 24.6 2.4 7.4 8.0 2.9 2 1 1 3 3 3 0 HAUS augmin-like complex subunit 6 N-terminus FUSC PF04632.7 KFH45467.1 - 1.7 7.0 6.0 2.9 6.2 4.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family ERM PF00769.14 KFH45467.1 - 3.3 7.1 40.1 0.2 11.1 11.0 2.5 1 1 1 2 2 2 0 Ezrin/radixin/moesin family FlaC_arch PF05377.6 KFH45467.1 - 7.8 6.4 17.3 7.1 6.6 0.2 4.6 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Ribosomal_L37 PF08561.5 KFH45468.1 - 0.024 14.1 0.3 0.068 12.7 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L37 Mito_fiss_reg PF05308.6 KFH45468.1 - 0.35 10.2 10.2 0.97 8.7 7.1 1.8 1 0 0 1 1 1 0 Mitochondrial fission regulator LSM PF01423.17 KFH45469.1 - 6.6e-11 41.5 0.0 8e-11 41.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KFH45469.1 - 0.005 16.7 0.0 0.0067 16.3 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain ADH_N PF08240.7 KFH45470.1 - 4.7e-23 81.0 0.7 1e-22 79.9 0.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 KFH45470.1 - 4.2e-08 32.6 0.2 4.2e-08 32.6 0.2 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.21 KFH45470.1 - 9.3e-07 28.4 0.0 0.00017 21.1 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase HDC PF02329.11 KFH45470.1 - 0.04 12.5 0.0 0.07 11.7 0.0 1.3 1 0 0 1 1 1 0 Histidine carboxylase PI chain APH PF01636.18 KFH45472.1 - 0.088 12.5 1.0 0.72 9.5 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family UDG PF03167.14 KFH45473.1 - 3.1e-25 88.4 0.0 5.3e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily SET PF00856.23 KFH45474.1 - 2.5e-18 66.9 3.8 1.2e-17 64.7 0.2 3.4 3 1 0 3 3 3 1 SET domain DUF1713 PF08213.6 KFH45475.1 - 1.2e-11 44.0 21.3 1.2e-11 44.0 14.7 1.8 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.5 KFH45475.1 - 0.022 14.7 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial protein Pet20 HHH PF00633.18 KFH45477.1 - 0.011 15.3 0.1 0.031 13.9 0.1 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF726 PF05277.7 KFH45478.1 - 6.6e-107 357.3 0.1 8.7e-107 356.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.15 KFH45478.1 - 0.00046 20.4 0.1 0.0013 19.0 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 KFH45478.1 - 0.0014 18.5 0.3 0.0014 18.5 0.2 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Cutinase PF01083.17 KFH45478.1 - 0.018 14.8 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Cutinase Abhydrolase_5 PF12695.2 KFH45478.1 - 0.028 14.1 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Gly-zipper_OmpA PF13436.1 KFH45478.1 - 0.74 9.4 7.0 7.8 6.1 1.7 2.5 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Glyco_hydro_92 PF07971.7 KFH45479.1 - 3.7e-167 556.9 0.0 4.7e-167 556.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Abhydrolase_5 PF12695.2 KFH45480.1 - 6e-18 64.9 0.4 1e-17 64.2 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFH45480.1 - 3e-06 27.2 7.0 6.8e-05 22.8 4.1 2.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 KFH45480.1 - 5.7e-05 21.5 0.0 0.0026 16.1 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Peptidase_S9 PF00326.16 KFH45480.1 - 0.028 13.6 0.1 0.071 12.3 0.1 1.8 1 1 0 1 1 1 0 Prolyl oligopeptidase family FSH1 PF03959.8 KFH45480.1 - 0.082 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Thg1C PF14413.1 KFH45481.1 - 1.7e-52 176.2 0.3 2.4e-52 175.7 0.2 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 KFH45481.1 - 2.8e-23 82.0 0.0 4.8e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase MFS_1 PF07690.11 KFH45482.1 - 4.3e-40 137.4 29.1 2.2e-28 98.9 3.2 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH45482.1 - 2.6e-09 36.1 6.4 2.6e-09 36.1 4.5 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter DUF4448 PF14610.1 KFH45483.1 - 3.9e-30 104.7 0.0 5.3e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) WD40 PF00400.27 KFH45484.1 - 6.9e-09 35.2 3.4 0.0031 17.3 0.0 4.4 5 0 0 5 5 5 3 WD domain, G-beta repeat PQQ PF01011.16 KFH45484.1 - 0.17 11.4 1.3 5.6 6.6 0.0 3.6 3 0 0 3 3 3 0 PQQ enzyme repeat DHDPS PF00701.17 KFH45485.1 - 7.3e-43 146.2 0.0 8.7e-43 145.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PALP PF00291.20 KFH45486.1 - 3.2e-56 190.8 0.5 3.9e-56 190.5 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme rve PF00665.21 KFH45486.1 - 0.02 14.9 0.2 2.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Integrase core domain APH PF01636.18 KFH45487.1 - 8e-16 58.4 0.0 1.6e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFH45487.1 - 0.0012 18.4 0.0 0.0025 17.4 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.17 KFH45487.1 - 0.0096 15.2 0.0 0.11 11.7 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.20 KFH45487.1 - 0.094 11.8 0.0 3.3 6.7 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain HSP70 PF00012.15 KFH45490.1 - 5.9e-192 638.7 3.2 6.6e-192 638.6 2.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFH45490.1 - 4.7e-15 54.9 0.2 8.5e-15 54.1 0.1 1.3 1 0 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.11 KFH45490.1 - 0.0034 17.0 0.0 0.0064 16.1 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FAD_binding_4 PF01565.18 KFH45492.1 - 1.9e-32 111.6 2.4 4e-32 110.5 1.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFH45492.1 - 1.6e-10 40.7 0.1 3e-10 39.8 0.1 1.4 1 0 0 1 1 1 1 Berberine and berberine like Glyco_hydro_12 PF01670.11 KFH45494.1 - 1.9e-15 56.9 0.1 2e-15 56.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 adh_short PF00106.20 KFH45495.1 - 7.5e-30 104.0 0.4 9.4e-30 103.7 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH45495.1 - 3.8e-26 92.3 0.0 4.6e-26 92.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH45495.1 - 2.7e-19 69.5 0.2 3.6e-19 69.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFH45495.1 - 2.1e-05 24.0 0.0 3.1e-05 23.5 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KFH45495.1 - 0.013 14.3 0.1 0.019 13.8 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain 3Beta_HSD PF01073.14 KFH45495.1 - 0.037 12.7 0.0 0.077 11.6 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF4644 PF15486.1 KFH45496.1 - 0.00078 19.4 0.0 0.37 10.7 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4644) RNA_pol_Rpb1_1 PF04997.7 KFH45497.1 - 3.9e-115 384.6 0.0 6e-115 384.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 KFH45497.1 - 9.3e-101 336.7 0.0 1.5e-100 336.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KFH45497.1 - 1.8e-70 236.2 0.0 3.5e-70 235.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 KFH45497.1 - 1.2e-54 184.8 0.8 2.1e-54 184.1 0.6 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 KFH45497.1 - 2.4e-46 157.3 0.0 5.4e-46 156.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 KFH45497.1 - 7.7e-45 151.9 7.4 2.3e-44 150.3 5.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 KFH45497.1 - 6.6e-36 122.3 0.1 1.6e-35 121.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 KFH45497.1 - 7.8 6.8 192.4 0.025 14.6 6.6 12.4 9 2 4 14 14 14 0 RNA polymerase Rpb1 C-terminal repeat RRM_1 PF00076.17 KFH45498.1 - 3.7e-73 241.1 0.7 2.1e-19 68.9 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH45498.1 - 4.6e-65 215.5 0.1 1.6e-15 56.7 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH45498.1 - 1e-37 127.7 0.0 1.1e-09 38.0 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFH45498.1 - 2.8e-06 27.1 0.6 1.3 8.9 0.0 4.6 4 1 1 5 5 5 2 RNA binding motif Nup35_RRM_2 PF14605.1 KFH45498.1 - 6e-06 25.9 0.0 2 8.2 0.0 4.0 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 KFH45498.1 - 2.8e-05 23.7 0.4 1.7 8.4 0.0 4.8 4 1 0 4 4 4 2 Limkain b1 5-nucleotidase PF06189.7 KFH45498.1 - 0.032 13.0 0.1 0.058 12.2 0.0 1.3 1 0 0 1 1 1 0 5'-nucleotidase NAD_binding_1 PF00175.16 KFH45499.1 - 1.3e-30 106.1 0.0 3.8e-30 104.6 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KFH45499.1 - 6.3e-22 77.5 0.0 1.4e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KFH45499.1 - 1e-08 35.2 0.0 0.00046 20.1 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KFH45499.1 - 0.0059 16.5 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain Ribosomal_60s PF00428.14 KFH45499.1 - 4.8 7.6 7.3 11 6.4 5.1 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Peptidase_M28 PF04389.12 KFH45502.1 - 9.1e-16 58.1 0.0 1.5e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 KFH45502.1 - 5.5e-14 51.8 0.0 1.1e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 KFH45502.1 - 1.1e-06 28.1 0.8 4.2e-06 26.3 0.1 2.2 2 0 0 2 2 2 1 PA domain Nicastrin PF05450.10 KFH45502.1 - 0.019 14.2 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 Nicastrin Sel1 PF08238.7 KFH45503.1 - 1.1e-37 127.5 42.8 0.00031 21.2 0.1 13.2 12 1 0 12 12 12 11 Sel1 repeat TPR_11 PF13414.1 KFH45503.1 - 0.022 14.3 0.2 0.022 14.3 0.2 5.3 6 1 1 7 7 7 0 TPR repeat XPG_N PF00752.12 KFH45504.1 - 1.5e-32 111.8 0.0 3.3e-32 110.7 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 KFH45504.1 - 1.1e-26 92.7 0.0 3.1e-26 91.2 0.0 1.9 1 0 0 1 1 1 1 XPG I-region Ssu72 PF04722.8 KFH45505.1 - 1.1e-84 282.7 0.0 1.2e-84 282.4 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Pil1 PF13805.1 KFH45506.1 - 1.7e-154 512.7 0.5 2.1e-154 512.4 0.3 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 KFH45506.1 - 0.0068 15.7 2.5 0.015 14.6 1.7 1.6 1 0 0 1 1 1 1 FAM92 protein DUF1708 PF08101.6 KFH45507.1 - 9.3e-156 518.8 0.0 1.3e-155 518.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) Drc1-Sld2 PF11719.3 KFH45511.1 - 0.012 14.7 24.3 0.014 14.5 16.9 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein SR-25 PF10500.4 KFH45511.1 - 1.5 8.2 52.1 9.2 5.6 18.4 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein SOBP PF15279.1 KFH45511.1 - 6.2 7.1 8.4 7.5 6.8 5.8 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Zip PF02535.17 KFH45511.1 - 9.9 5.0 5.8 18 4.2 4.0 1.5 1 1 0 1 1 1 0 ZIP Zinc transporter Mpv17_PMP22 PF04117.7 KFH45512.1 - 6.3e-27 93.0 6.4 1.3e-26 92.0 4.4 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Acetyltransf_1 PF00583.19 KFH45513.1 - 4.5e-13 49.0 0.2 7.2e-13 48.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 KFH45513.1 - 0.00025 20.9 0.1 0.00032 20.6 0.1 1.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KFH45513.1 - 0.0012 18.9 0.0 0.0018 18.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFH45513.1 - 0.0013 18.8 0.1 0.0031 17.6 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFH45513.1 - 0.0013 18.4 0.2 0.0031 17.2 0.1 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 KFH45513.1 - 0.0024 17.7 0.1 0.0046 16.8 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 KFH45513.1 - 0.0041 16.9 0.1 0.0081 16.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.1 KFH45513.1 - 0.023 15.2 0.0 0.038 14.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SRP54 PF00448.17 KFH45513.1 - 0.03 13.7 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain zf-met2 PF12907.2 KFH45514.1 - 9.5e-18 63.8 4.9 1.5e-17 63.2 3.4 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 KFH45514.1 - 1.4e-08 35.2 10.6 1.4e-08 35.2 7.3 1.9 2 0 0 2 2 2 1 4F5 protein family HypA PF01155.14 KFH45514.1 - 0.015 15.0 0.2 0.017 14.8 0.1 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DUF1644 PF07800.7 KFH45514.1 - 0.1 12.4 1.5 0.13 12.1 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) Katanin_con80 PF13925.1 KFH45514.1 - 0.31 10.7 2.8 0.35 10.5 2.0 1.1 1 0 0 1 1 1 0 con80 domain of Katanin Ribosomal_L44 PF00935.14 KFH45514.1 - 2.9 7.9 5.9 13 5.8 4.1 1.9 1 1 0 1 1 1 0 Ribosomal protein L44 JmjC PF02373.17 KFH45515.1 - 5e-19 68.6 0.0 9e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase WD40 PF00400.27 KFH45516.1 - 1.7e-09 37.2 3.6 0.016 15.0 0.4 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF1191 PF06697.7 KFH45516.1 - 0.15 10.8 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) RNA_pol_N PF01194.12 KFH45517.1 - 1e-28 99.0 1.0 1.3e-28 98.7 0.7 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 KFH45517.1 - 0.048 13.7 0.2 0.077 13.1 0.1 1.3 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Mqo PF06039.10 KFH45517.1 - 0.083 11.0 0.0 0.096 10.8 0.0 1.0 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) SprT-like PF10263.4 KFH45518.1 - 7.1e-12 45.2 0.0 7.1e-12 45.2 0.0 1.6 2 0 0 2 2 2 1 SprT-like family PAS_4 PF08448.5 KFH45519.1 - 0.0021 18.0 0.3 0.72 9.9 0.0 2.1 2 0 0 2 2 2 2 PAS fold DIOX_N PF14226.1 KFH45520.1 - 7e-28 97.4 0.1 6e-27 94.4 0.0 2.1 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KFH45520.1 - 4.3e-15 55.8 0.0 7.6e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Brucella_OMP2 PF05244.6 KFH45520.1 - 0.13 11.4 0.3 0.22 10.6 0.2 1.4 1 1 0 1 1 1 0 Brucella outer membrane protein 2 Methyltransf_28 PF02636.12 KFH45521.1 - 6.1e-37 127.3 0.0 1.1e-36 126.5 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.11 KFH45521.1 - 0.0094 14.9 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_16 PF10294.4 KFH45523.1 - 3.3e-17 62.4 0.0 5.3e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 KFH45523.1 - 0.044 13.1 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain F-box-like PF12937.2 KFH45524.1 - 3.4e-08 33.0 0.6 8.2e-08 31.8 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFH45524.1 - 2.9e-07 29.9 0.5 6.2e-07 28.9 0.3 1.6 1 0 0 1 1 1 1 F-box domain Epimerase PF01370.16 KFH45525.1 - 2.7e-09 36.8 0.0 0.0021 17.5 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFH45525.1 - 3.3e-05 23.9 0.0 6.2e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KFH45525.1 - 0.01 16.1 0.1 0.035 14.4 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_trans_1_4 PF13692.1 KFH45525.1 - 0.022 14.9 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Saccharop_dh PF03435.13 KFH45525.1 - 0.03 13.2 0.0 0.046 12.6 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KFH45525.1 - 0.041 13.9 0.0 0.069 13.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.8 KFH45525.1 - 0.096 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family 3Beta_HSD PF01073.14 KFH45525.1 - 0.13 10.8 0.0 0.26 9.9 0.0 1.5 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Bap31 PF05529.7 KFH45526.1 - 2.1e-63 213.2 4.8 2.5e-63 213.0 3.3 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like CCDC-167 PF15188.1 KFH45526.1 - 0.0094 15.8 1.7 0.021 14.7 1.2 1.6 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 Mod_r PF07200.8 KFH45526.1 - 0.028 14.3 1.6 0.041 13.7 1.1 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF192 PF02643.10 KFH45526.1 - 0.029 14.0 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized ACR, COG1430 TMF_DNA_bd PF12329.3 KFH45526.1 - 0.035 13.8 6.8 0.041 13.6 4.0 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Prefoldin_2 PF01920.15 KFH45526.1 - 0.056 13.2 0.9 0.056 13.2 0.6 1.6 2 0 0 2 2 2 0 Prefoldin subunit PEP-utilisers_N PF05524.8 KFH45526.1 - 0.073 12.8 0.4 0.12 12.1 0.3 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Spc7 PF08317.6 KFH45526.1 - 0.081 11.5 2.2 0.1 11.2 1.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 KFH45526.1 - 0.12 11.9 1.9 0.19 11.3 1.3 1.4 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 KFH45526.1 - 0.22 11.0 5.4 0.15 11.5 0.6 2.8 3 1 1 4 4 4 0 Septum formation initiator TBPIP PF07106.8 KFH45526.1 - 0.24 10.9 4.2 1.6 8.2 0.9 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) bZIP_1 PF00170.16 KFH45526.1 - 3.9 7.4 7.2 3.1 7.8 1.3 2.5 2 0 0 2 2 2 0 bZIP transcription factor Pro_isomerase PF00160.16 KFH45530.1 - 1e-48 165.4 0.2 1.2e-48 165.1 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.1 KFH45530.1 - 0.057 13.2 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain TEA PF01285.13 KFH45532.1 - 1.3e-16 60.8 0.0 1e-12 47.9 0.0 2.6 2 0 0 2 2 2 2 TEA/ATTS domain family BAF1_ABF1 PF04684.8 KFH45532.1 - 2.7 6.7 8.5 5.8 5.6 5.9 1.5 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor NmrA PF05368.8 KFH45533.1 - 1.9e-18 66.5 0.0 2.1e-18 66.4 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family Shikimate_DH PF01488.15 KFH45533.1 - 2.7e-05 24.2 0.0 0.053 13.6 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 KFH45533.1 - 0.019 13.9 0.0 0.032 13.2 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase GRA6 PF05084.8 KFH45534.1 - 0.041 13.3 0.0 0.084 12.3 0.0 1.5 1 0 0 1 1 1 0 Granule antigen protein (GRA6) RdRP PF05183.7 KFH45535.1 - 3.1e-85 287.0 0.0 3e-76 257.3 0.0 2.2 2 0 0 2 2 2 2 RNA dependent RNA polymerase Pyr_redox_2 PF07992.9 KFH45536.1 - 6.9e-18 65.2 0.1 8.6e-18 64.9 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFH45536.1 - 1.3e-05 24.2 1.2 0.00084 18.2 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KFH45536.1 - 0.00023 20.1 2.3 0.00023 20.1 0.4 1.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KFH45536.1 - 0.00028 20.0 0.1 0.00088 18.4 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KFH45536.1 - 0.00083 17.9 0.1 0.0013 17.3 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 KFH45536.1 - 0.0011 18.9 0.0 0.0025 17.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KFH45536.1 - 0.0024 16.8 0.0 0.0033 16.4 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KFH45536.1 - 0.003 17.6 0.2 0.0069 16.4 0.1 1.6 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFH45536.1 - 0.035 13.0 0.1 1.1 8.1 0.0 2.2 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 KFH45536.1 - 0.036 13.1 0.1 0.11 11.5 0.0 1.8 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.1 KFH45536.1 - 0.05 13.3 0.9 0.11 12.2 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.17 KFH45536.1 - 0.63 8.8 3.4 1.1 8.0 0.4 2.6 2 2 1 3 3 3 0 Glucose inhibited division protein A adh_short PF00106.20 KFH45537.1 - 1.1e-27 97.0 3.2 1.4e-27 96.6 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH45537.1 - 4e-17 62.7 0.0 5.1e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH45537.1 - 1.8e-08 34.2 1.8 2.7e-08 33.6 1.2 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KFH45537.1 - 0.00025 20.7 0.2 0.00041 20.0 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 KFH45537.1 - 0.0052 16.2 0.1 0.0086 15.5 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_18 PF12847.2 KFH45537.1 - 0.023 15.2 0.1 0.055 14.0 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain THF_DHG_CYH_C PF02882.14 KFH45537.1 - 0.063 12.3 0.0 0.16 11.0 0.0 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.10 KFH45537.1 - 0.07 12.0 0.0 0.096 11.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 KFH45537.1 - 0.32 10.8 2.1 0.95 9.2 0.4 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_hydro_10 PF00331.15 KFH45538.1 - 1.5e-87 293.6 0.0 1.7e-87 293.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CWC25 PF12542.3 KFH45539.1 - 9.6e-25 86.8 0.1 9.6e-25 86.8 0.1 3.5 4 1 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 KFH45539.1 - 3.2e-13 49.4 3.4 3.2e-13 49.4 2.4 3.9 4 0 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR Methyltransf_23 PF13489.1 KFH45540.1 - 1.1e-12 47.9 0.0 1.6e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH45540.1 - 7.4e-09 36.1 0.0 5.6e-08 33.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH45540.1 - 3.9e-08 33.6 0.0 7.4e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH45540.1 - 2.7e-07 30.2 0.0 5.7e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH45540.1 - 1.4e-06 28.7 0.0 2.9e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFH45540.1 - 0.00025 20.4 0.0 0.0012 18.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KFH45540.1 - 0.00062 20.0 0.0 0.0015 18.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KFH45540.1 - 0.00071 18.6 0.0 0.0021 17.1 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 KFH45540.1 - 0.0063 16.5 0.1 0.018 15.0 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFH45540.1 - 0.051 12.6 0.0 0.98 8.4 0.0 2.0 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family FAM220 PF15487.1 KFH45541.1 - 0.2 10.9 0.9 0.34 10.2 0.7 1.4 1 0 0 1 1 1 0 FAM220 family MutS_IV PF05190.13 KFH45542.1 - 0.11 12.6 0.2 0.17 12.0 0.1 1.2 1 0 0 1 1 1 0 MutS family domain IV DUF4110 PF13422.1 KFH45542.1 - 0.32 10.8 3.6 0.52 10.1 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) Neisseria_TspB PF05616.8 KFH45542.1 - 0.52 8.6 6.7 0.71 8.1 4.7 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Trypan_PARP PF05887.6 KFH45542.1 - 6.8 6.5 14.5 3.6 7.4 8.2 1.8 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Abhydro_lipase PF04083.11 KFH45543.1 - 8.7e-18 63.4 0.0 1.7e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 KFH45543.1 - 4.6e-07 29.9 0.1 9.5e-07 28.9 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH45543.1 - 0.0064 16.2 0.0 0.013 15.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFH45543.1 - 0.016 14.8 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold TauD PF02668.11 KFH45544.1 - 6.2e-28 98.1 0.1 1e-27 97.4 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Citrate_synt PF00285.16 KFH45545.1 - 3e-101 338.6 0.0 3.6e-101 338.4 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase APG17 PF04108.7 KFH45546.1 - 8.1e-91 304.8 0.0 9.4e-91 304.6 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 AMP-binding PF00501.23 KFH45547.1 - 2.6e-82 276.4 0.0 4.2e-82 275.7 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KFH45547.1 - 2e-62 210.3 0.0 1e-61 208.0 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 KFH45547.1 - 6.3e-36 123.8 8.5 2.2e-33 115.5 2.0 3.5 3 1 0 3 3 3 2 short chain dehydrogenase KR PF08659.5 KFH45547.1 - 4.5e-21 75.3 5.4 2.7e-17 62.9 1.3 2.8 2 0 0 2 2 2 2 KR domain Epimerase PF01370.16 KFH45547.1 - 1.2e-19 70.6 0.1 2.4e-12 46.7 0.0 3.2 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KFH45547.1 - 5.3e-19 68.9 0.3 1.4e-18 67.5 0.2 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.20 KFH45547.1 - 1.4e-11 44.5 0.0 3.3e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.1 KFH45547.1 - 2.2e-09 37.5 0.9 0.0019 18.1 0.7 4.0 2 2 0 2 2 2 2 NADH(P)-binding AMP-binding_C PF13193.1 KFH45547.1 - 3.7e-09 37.3 0.6 2.1e-08 34.9 0.4 2.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 KFH45547.1 - 6.7e-09 34.8 0.0 0.00049 18.8 0.0 2.8 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KFH45547.1 - 1.1e-08 34.3 0.7 2.6e-05 23.2 0.0 3.4 2 1 0 2 2 2 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KFH45547.1 - 9.2e-06 24.7 0.5 0.14 11.0 0.0 2.8 3 1 0 3 3 3 2 Polysaccharide biosynthesis protein NmrA PF05368.8 KFH45547.1 - 0.16 11.1 0.7 30 3.7 0.9 2.6 2 0 0 2 2 2 0 NmrA-like family Eno-Rase_NADH_b PF12242.3 KFH45547.1 - 0.26 11.0 3.3 0.9 9.3 2.3 1.9 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Alpha-amylase PF00128.19 KFH45548.1 - 5.8e-99 331.4 0.0 9.4e-99 330.7 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 KFH45548.1 - 0.0039 16.1 0.0 0.008 15.1 0.0 1.4 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Ank_2 PF12796.2 KFH45549.1 - 2.3e-35 120.7 0.2 2.6e-08 34.0 0.0 7.3 4 2 3 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KFH45549.1 - 6.4e-23 79.3 13.8 0.00071 19.2 0.0 11.9 13 0 0 13 13 13 4 Ankyrin repeat Ank_5 PF13857.1 KFH45549.1 - 7.9e-20 70.4 12.4 1.8e-06 27.9 0.1 9.7 10 1 1 11 11 11 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFH45549.1 - 1.2e-19 68.4 2.2 0.64 10.4 0.0 11.6 12 0 0 12 12 12 5 Ankyrin repeat Ank_4 PF13637.1 KFH45549.1 - 4.7e-18 65.1 5.4 0.14 12.6 0.0 10.3 9 2 2 11 11 11 5 Ankyrin repeats (many copies) Shigella_OspC PF06128.6 KFH45549.1 - 0.056 12.9 0.0 1.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Shigella flexneri OspC protein APH PF01636.18 KFH45550.1 - 0.017 14.8 0.1 0.047 13.4 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family EcKinase PF02958.15 KFH45550.1 - 0.037 13.1 0.0 0.062 12.4 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.15 KFH45551.1 - 1.7e-09 37.5 0.2 2.1e-09 37.2 0.2 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 KFH45551.1 - 4.9e-09 36.2 0.0 6.5e-09 35.8 0.0 1.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KFH45551.1 - 0.019 13.6 0.0 0.023 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) DUF1579 PF07617.6 KFH45553.1 - 0.033 13.8 0.0 0.04 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1579) NicO PF03824.11 KFH45554.1 - 2e-63 214.3 4.3 2e-63 214.3 3.0 1.5 2 0 0 2 2 2 1 High-affinity nickel-transport protein Herpes_gE PF02480.11 KFH45554.1 - 0.00068 18.0 0.0 0.0031 15.8 0.0 2.0 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E MFS_Mycoplasma PF07672.8 KFH45554.1 - 0.02 14.0 0.0 0.82 8.7 1.7 2.1 2 0 0 2 2 2 0 Mycoplasma MFS transporter HAMP PF00672.20 KFH45554.1 - 0.076 13.2 0.0 0.076 13.2 0.0 4.0 4 0 0 4 4 4 0 HAMP domain DUF3632 PF12311.3 KFH45555.1 - 8.8e-12 45.1 0.1 3e-11 43.4 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3632) 4HBT PF03061.17 KFH45557.1 - 3.5e-10 39.8 1.1 5.9e-10 39.1 0.8 1.4 1 0 0 1 1 1 1 Thioesterase superfamily MFS_1 PF07690.11 KFH45558.1 - 6.6e-33 113.8 17.9 6.6e-33 113.8 12.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH45558.1 - 2.3e-08 33.0 5.2 2.3e-08 33.0 3.6 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.8 KFH45558.1 - 0.0021 16.2 3.1 0.0021 16.2 2.1 2.4 3 0 0 3 3 3 1 Transmembrane secretion effector MFS_2 PF13347.1 KFH45558.1 - 0.026 12.9 20.2 0.011 14.1 2.6 3.4 2 2 0 3 3 3 0 MFS/sugar transport protein Mito_carr PF00153.22 KFH45559.1 - 6.9e-48 160.3 3.5 5.2e-20 70.9 0.2 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein CAP_GLY PF01302.20 KFH45562.1 - 0.095 12.4 0.0 0.19 11.4 0.0 1.5 2 0 0 2 2 2 0 CAP-Gly domain MFS_1 PF07690.11 KFH45563.1 - 8.9e-37 126.6 27.8 8.9e-37 126.6 19.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily RskA PF10099.4 KFH45563.1 - 0.19 11.4 1.5 3.6 7.2 0.0 2.6 2 0 0 2 2 2 0 Anti-sigma-K factor rskA PALP PF00291.20 KFH45565.1 - 1.5e-27 96.6 0.1 1.9e-27 96.3 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LMSTEN PF07988.7 KFH45565.1 - 0.067 12.5 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 LMSTEN motif DUF212 PF02681.9 KFH45565.1 - 0.1 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Divergent PAP2 family EGF_3 PF12947.2 KFH45566.1 - 1.3e-05 25.0 39.1 0.65 10.0 0.7 7.0 4 3 0 4 4 4 4 EGF domain Fungal_trans PF04082.13 KFH45567.1 - 1.5e-17 63.3 0.6 2.7e-17 62.5 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH45567.1 - 2.5e-08 33.6 13.0 6e-08 32.4 9.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LGT PF01790.13 KFH45568.1 - 0.082 11.8 0.1 3.8 6.3 0.0 2.0 2 0 0 2 2 2 0 Prolipoprotein diacylglyceryl transferase DUF2484 PF10658.4 KFH45568.1 - 0.099 12.7 1.9 0.13 12.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2484) Claudin_2 PF13903.1 KFH45568.1 - 0.11 12.1 2.5 4.9 6.8 1.7 2.2 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF202 PF02656.10 KFH45568.1 - 0.48 10.6 4.0 3.3 7.9 1.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Asp PF00026.18 KFH45569.1 - 8.8e-67 225.5 0.5 1e-66 225.3 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFH45569.1 - 3.7e-06 26.9 0.0 2.1e-05 24.5 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KFH45569.1 - 0.0081 15.7 0.0 0.026 14.0 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Glyco_hydro_92 PF07971.7 KFH45570.1 - 1.2e-147 492.6 2.4 1.4e-147 492.3 1.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 SpoIIE PF07228.7 KFH45571.1 - 2.8e-12 46.7 0.4 9.5e-12 45.0 0.3 1.8 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KFH45571.1 - 4.3e-11 42.6 0.1 7.3e-11 41.8 0.1 1.3 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 KFH45571.1 - 0.0012 18.3 0.0 0.0092 15.3 0.0 2.1 2 0 0 2 2 2 1 Protein phosphatase 2C Ribosomal_S14 PF00253.16 KFH45573.1 - 1e-16 60.0 1.6 4.1e-16 58.0 0.2 2.0 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e Arylsulfotran_2 PF14269.1 KFH45574.1 - 3.2e-61 207.0 0.5 4.4e-61 206.6 0.3 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KFH45574.1 - 3.7e-20 71.8 0.1 6.7e-20 71.0 0.1 1.4 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Kelch_3 PF13415.1 KFH45574.1 - 0.057 13.6 0.8 1.6 8.9 0.1 3.5 5 0 0 5 5 5 0 Galactose oxidase, central domain Choline_transpo PF04515.7 KFH45575.1 - 2e-106 355.5 13.4 2e-106 355.5 9.3 2.0 2 0 0 2 2 2 1 Plasma-membrane choline transporter ICL PF00463.16 KFH45576.1 - 8.5e-200 664.4 0.0 9.8e-200 664.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KFH45576.1 - 1.8e-12 46.9 0.1 6.1e-10 38.7 0.0 2.3 2 0 0 2 2 2 2 Phosphoenolpyruvate phosphomutase Gln-synt_C PF00120.19 KFH45577.1 - 3.3e-61 206.7 0.0 4.3e-61 206.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain DUF2580 PF10824.3 KFH45577.1 - 0.18 12.1 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2580) E1-E2_ATPase PF00122.15 KFH45578.1 - 7.3e-59 198.5 9.4 7.3e-59 198.5 6.5 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KFH45578.1 - 2e-30 106.8 0.0 6.3e-29 101.9 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 KFH45578.1 - 2.6e-29 102.0 0.9 2.6e-29 102.0 0.6 2.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.21 KFH45578.1 - 1e-16 60.1 0.0 2.7e-16 58.7 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KFH45578.1 - 3.6e-14 52.4 0.1 9.9e-14 51.0 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KFH45578.1 - 1.6e-13 51.2 0.2 1.7e-12 47.8 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFH45578.1 - 1e-05 25.2 0.3 0.00017 21.2 0.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3650 PF12368.3 KFH45578.1 - 0.28 10.7 0.0 0.58 9.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3650) Ras PF00071.17 KFH45580.1 - 7.5e-53 178.2 0.0 8.7e-53 178.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFH45580.1 - 9.7e-16 58.3 0.0 1.3e-15 57.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFH45580.1 - 5.8e-09 35.4 0.0 1.1e-08 34.5 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFH45580.1 - 0.00014 21.0 0.0 0.00017 20.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFH45580.1 - 0.0032 17.3 0.0 0.0044 16.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KFH45580.1 - 0.0043 16.2 0.0 0.0057 15.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KFH45580.1 - 0.0059 15.3 0.0 0.012 14.3 0.0 1.5 1 1 0 1 1 1 1 G-protein alpha subunit GTP_EFTU PF00009.22 KFH45580.1 - 0.016 14.6 0.0 0.078 12.3 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Glyco_hydro_16 PF00722.16 KFH45581.1 - 1.6e-39 135.1 1.0 2.6e-39 134.4 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Laminin_G_3 PF13385.1 KFH45581.1 - 0.056 13.6 1.5 0.12 12.5 1.1 1.7 1 1 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily DUF3258 PF11646.3 KFH45581.1 - 0.1 12.8 0.1 0.18 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF3258 SGL PF08450.7 KFH45582.1 - 0.0062 15.9 0.0 0.024 14.0 0.0 1.8 1 1 1 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Kelch_3 PF13415.1 KFH45582.1 - 0.023 14.8 1.5 0.1 12.7 0.0 2.8 3 0 0 3 3 3 0 Galactose oxidase, central domain Glyco_hydro_62 PF03664.8 KFH45583.1 - 2.9e-133 443.0 3.0 3.3e-133 442.8 2.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Zn_clus PF00172.13 KFH45584.1 - 1.6e-09 37.5 9.8 3.2e-09 36.5 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease PF00324.16 KFH45585.1 - 7.2e-134 446.7 46.4 8.8e-134 446.4 32.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFH45585.1 - 9.8e-35 119.8 51.0 1.2e-34 119.5 35.4 1.0 1 0 0 1 1 1 1 Amino acid permease Sugar_tr PF00083.19 KFH45586.1 - 1.1e-88 297.7 17.0 1.4e-88 297.5 11.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH45586.1 - 5.1e-22 78.0 19.8 4.5e-14 51.9 6.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFH45586.1 - 7.3e-06 24.6 29.1 0.0015 16.9 0.9 3.8 2 2 2 4 4 4 3 MFS/sugar transport protein Peptidase_C65 PF10275.4 KFH45587.1 - 1.7e-49 168.4 0.0 6.6e-49 166.4 0.0 1.7 1 1 0 1 1 1 1 Peptidase C65 Otubain Peptidase_C2 PF00648.16 KFH45588.1 - 7.9e-50 169.5 10.7 5.6e-36 124.0 0.2 3.2 3 0 0 3 3 3 2 Calpain family cysteine protease Amidohydro_5 PF13594.1 KFH45588.1 - 0.14 11.9 0.4 0.53 10.1 0.0 2.1 2 0 0 2 2 2 0 Amidohydrolase Ldh_2 PF02615.9 KFH45589.1 - 1.1e-93 313.6 0.0 1.3e-93 313.4 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase SLR1-BP PF07333.7 KFH45590.1 - 0.00052 20.1 4.0 0.00078 19.6 2.8 1.2 1 0 0 1 1 1 1 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) Gamma-thionin PF00304.15 KFH45590.1 - 0.0092 15.9 5.2 0.014 15.3 3.6 1.2 1 0 0 1 1 1 1 Gamma-thionin family Defensin_2 PF01097.13 KFH45590.1 - 0.013 15.2 6.9 0.02 14.6 4.8 1.3 1 0 0 1 1 1 0 Arthropod defensin Metallothi_Euk2 PF12809.2 KFH45590.1 - 0.053 13.9 3.0 0.078 13.3 2.1 1.2 1 0 0 1 1 1 0 Eukaryotic metallothionein Toxin_31 PF08119.6 KFH45590.1 - 0.25 10.8 4.8 0.43 10.1 3.3 1.3 1 0 0 1 1 1 0 Scorpion acidic alpha-KTx toxin family Myticin-prepro PF10690.4 KFH45590.1 - 0.55 10.2 4.7 0.8 9.7 3.3 1.3 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel EGF_2 PF07974.8 KFH45590.1 - 3.7 7.7 7.5 11 6.2 5.2 1.9 1 1 0 1 1 1 0 EGF-like domain Zn_clus PF00172.13 KFH45591.1 - 2.3e-09 37.0 8.0 4e-09 36.2 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFH45591.1 - 1e-05 24.5 0.1 1.8e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PCI PF01399.22 KFH45592.1 - 9.7e-19 67.6 0.1 3.7e-18 65.7 0.0 2.1 2 1 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 KFH45592.1 - 4.6e-08 32.9 0.1 1.1e-07 31.7 0.1 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 DUF4423 PF14394.1 KFH45592.1 - 0.017 14.7 0.0 0.054 13.0 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) FeoC PF09012.5 KFH45592.1 - 0.033 13.8 0.0 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 FeoC like transcriptional regulator GPAT_N PF14829.1 KFH45592.1 - 0.083 12.5 0.1 0.26 11.0 0.1 1.8 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal Pkinase PF00069.20 KFH45593.1 - 6.5e-17 61.5 0.0 8.9e-17 61.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH45593.1 - 0.0098 14.9 0.0 0.17 10.9 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase GTPase_binding PF09027.5 KFH45594.1 - 0.089 12.3 0.0 0.29 10.7 0.0 1.9 2 0 0 2 2 2 0 GTPase binding Mito_carr PF00153.22 KFH45597.1 - 8e-43 144.0 0.5 2.6e-19 68.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.11 KFH45598.1 - 5.1e-19 68.2 34.1 1.1e-18 67.1 23.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_88 PF07470.8 KFH45599.1 - 5.2e-85 285.4 1.2 6e-85 285.2 0.8 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.9 KFH45599.1 - 0.019 14.3 5.7 0.049 13.0 0.6 2.5 1 1 1 2 2 2 0 Glycosyl hydrolase family 76 DUF1680 PF07944.7 KFH45599.1 - 0.037 12.3 0.2 0.075 11.2 0.1 1.5 1 1 0 1 1 1 0 Putative glycosyl hydrolase of unknown function (DUF1680) MiaE PF06175.6 KFH45599.1 - 0.13 11.6 0.1 0.27 10.5 0.0 1.5 2 0 0 2 2 2 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) CoA_trans PF01144.18 KFH45600.1 - 1.8e-91 305.1 2.4 5.3e-52 176.1 0.1 2.4 2 1 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 KFH45600.1 - 0.0044 16.7 0.1 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain RIO1 PF01163.17 KFH45602.1 - 3.3e-67 225.4 0.2 7.1e-67 224.4 0.0 1.6 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 KFH45602.1 - 0.00049 19.8 0.1 0.19 11.4 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KFH45602.1 - 0.015 14.3 0.0 0.093 11.7 0.0 2.1 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1115 PF06544.7 KFH45603.1 - 1.1e-20 73.5 0.0 2.1e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) MFS_1 PF07690.11 KFH45604.1 - 1.1e-22 80.3 53.2 3.9e-14 52.1 16.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Rieske PF00355.21 KFH45605.1 - 6.5e-10 38.4 0.0 9.8e-10 37.8 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 KFH45605.1 - 1.3e-06 28.0 0.0 2.1e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Cnd1_N PF12922.2 KFH45606.1 - 5.6e-56 188.8 0.0 4.3e-55 185.9 0.0 2.4 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.2 KFH45606.1 - 1.1e-53 181.6 1.4 4.2e-49 166.8 0.0 3.0 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KFH45606.1 - 6.9e-11 42.2 4.6 8.8e-06 25.9 0.1 5.6 4 2 0 4 4 4 2 HEAT repeats HEAT PF02985.17 KFH45606.1 - 3.2e-07 29.8 9.7 0.03 14.4 0.0 5.8 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 KFH45606.1 - 1.9e-05 24.9 4.9 0.071 13.6 0.1 5.2 4 0 0 4 4 4 1 HEAT-like repeat DUF2435 PF10363.4 KFH45606.1 - 0.022 14.6 0.0 2 8.3 0.0 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2435) Cnd3 PF12719.2 KFH45606.1 - 0.024 13.6 3.2 0.069 12.1 0.2 3.1 2 1 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain Cohesin_HEAT PF12765.2 KFH45606.1 - 0.28 11.1 5.8 13 5.8 0.1 3.9 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion GRIM-19 PF06212.7 KFH45607.1 - 2.3e-24 85.5 0.1 3.4e-24 84.9 0.1 1.2 1 1 0 1 1 1 1 GRIM-19 protein Ribosomal_L18e PF00828.14 KFH45608.1 - 4.5e-33 114.3 0.0 5.5e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 NmrA PF05368.8 KFH45610.1 - 1.7e-17 63.4 0.0 2.4e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFH45610.1 - 1.5e-14 54.4 0.1 1.1e-13 51.6 0.0 2.1 1 1 1 2 2 2 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KFH45610.1 - 0.088 11.6 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Semialdhyde_dh PF01118.19 KFH45610.1 - 0.11 12.7 0.0 0.36 11.1 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Abhydrolase_1 PF00561.15 KFH45611.1 - 1.1e-19 70.9 0.0 9.4e-19 67.8 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KFH45611.1 - 7.4e-11 42.3 3.0 6.5e-10 39.2 2.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KFH45611.1 - 0.0011 18.4 0.0 0.0021 17.5 0.0 1.5 1 0 0 1 1 1 1 Putative esterase ORC6 PF05460.8 KFH45611.1 - 0.013 14.6 0.3 0.013 14.6 0.2 1.8 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) DUF2167 PF09935.4 KFH45614.1 - 0.11 11.3 0.2 0.3 9.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2167) Ric8 PF10165.4 KFH45616.1 - 0.066 12.0 0.1 0.1 11.3 0.1 1.2 1 0 0 1 1 1 0 Guanine nucleotide exchange factor synembryn Chorismate_bind PF00425.13 KFH45617.1 - 2.3e-68 230.3 0.0 9.1e-68 228.3 0.0 1.9 1 1 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 KFH45617.1 - 2.1e-27 95.8 0.0 3.7e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 KFH45617.1 - 7.2e-18 64.9 0.0 1.7e-17 63.7 0.0 1.7 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 KFH45617.1 - 0.00083 18.8 0.0 0.072 12.5 0.0 2.4 2 0 0 2 2 2 2 Peptidase C26 HMGL-like PF00682.14 KFH45618.1 - 2.2e-50 171.5 0.6 2.5e-48 164.8 0.4 2.4 1 1 0 1 1 1 1 HMGL-like Peptidase_M14 PF00246.19 KFH45619.1 - 6.9e-38 130.8 0.0 9.9e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase NUDIX PF00293.23 KFH45620.1 - 8.7e-09 35.1 0.0 1.4e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Aldo_ket_red PF00248.16 KFH45621.1 - 3e-45 154.2 0.0 3.8e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Mito_carr PF00153.22 KFH45622.1 - 1e-56 188.6 5.3 1.8e-24 85.2 0.2 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein PP-binding PF00550.20 KFH45623.1 - 1.7e-10 40.9 0.1 2.4e-10 40.5 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 KFH45623.1 - 0.00011 22.2 0.3 0.00015 21.7 0.2 1.4 1 1 0 1 1 1 1 Acyl-carrier Peptidase_M28 PF04389.12 KFH45625.1 - 3.3e-34 118.1 0.0 6.9e-34 117.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KFH45625.1 - 1.5e-19 69.5 0.2 4.1e-19 68.1 0.1 1.8 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 KFH45625.1 - 1.4e-06 28.0 0.0 2.4e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Fungal_trans PF04082.13 KFH45626.1 - 8.8e-12 44.4 0.3 1.4e-11 43.7 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH45626.1 - 1.1e-05 25.2 9.2 2.5e-05 24.0 6.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 KFH45626.1 - 5.6e-05 23.1 3.3 5.6e-05 23.1 2.3 3.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KFH45626.1 - 0.00015 21.9 20.1 0.0011 19.1 2.8 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KFH45626.1 - 0.095 12.8 0.2 0.095 12.8 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 KFH45626.1 - 1 9.7 14.5 0.99 9.8 0.1 4.0 3 1 0 3 3 3 0 Zinc-finger double domain DUF2370 PF10176.4 KFH45629.1 - 1.2e-83 280.0 1.1 3.6e-83 278.5 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2370) TFIIF_alpha PF05793.7 KFH45629.1 - 0.7 8.1 3.7 1 7.6 2.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PQQ_3 PF13570.1 KFH45629.1 - 3.4 8.0 7.3 2.7 8.3 1.0 2.9 3 0 0 3 3 3 0 PQQ-like domain Beta-lactamase PF00144.19 KFH45631.1 - 4.7e-40 137.6 0.1 6.9e-40 137.0 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase ATP-grasp_4 PF13535.1 KFH45632.1 - 4.9e-05 23.1 0.0 0.00012 21.8 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KFH45632.1 - 0.0085 14.8 0.0 0.042 12.6 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Aldedh PF00171.17 KFH45633.1 - 4.3e-136 453.9 1.6 5.1e-136 453.6 1.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KFH45633.1 - 0.00038 19.2 0.0 0.00057 18.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) SNF2_N PF00176.18 KFH45634.1 - 5.1e-50 169.9 0.0 7.7e-50 169.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KFH45634.1 - 1.6e-09 37.8 0.0 4.2e-09 36.5 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KFH45634.1 - 2.6e-07 30.3 0.1 2.1e-06 27.3 0.0 2.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase DUF966 PF06136.8 KFH45635.1 - 0.11 11.9 1.5 0.16 11.3 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Ribosomal_60s PF00428.14 KFH45635.1 - 0.13 12.7 7.6 0.38 11.1 5.3 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein RRN9 PF10680.4 KFH45636.1 - 0.05 13.3 0.1 0.079 12.6 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor Helicase_C_2 PF13307.1 KFH45638.1 - 2.5e-59 199.9 0.0 5.2e-59 198.9 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 KFH45638.1 - 7.5e-40 136.1 0.0 1.3e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.10 KFH45638.1 - 0.006 16.4 0.1 0.53 10.0 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KFH45638.1 - 0.048 13.1 0.1 0.31 10.5 0.0 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase bZIP_1 PF00170.16 KFH45641.1 - 6.4e-10 38.8 6.3 1.1e-09 38.0 4.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFH45641.1 - 5.1e-07 29.4 11.7 1.1e-06 28.3 8.1 1.6 1 0 0 1 1 1 1 Basic region leucine zipper TPD52 PF04201.10 KFH45641.1 - 0.028 14.1 1.1 0.057 13.1 0.8 1.5 1 0 0 1 1 1 0 Tumour protein D52 family Macoilin PF09726.4 KFH45641.1 - 0.24 9.6 4.2 0.3 9.3 2.9 1.1 1 0 0 1 1 1 0 Transmembrane protein PRCC PF10253.4 KFH45641.1 - 0.39 11.3 12.3 0.17 12.5 3.9 2.1 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting CAF-1_p150 PF11600.3 KFH45641.1 - 0.52 9.6 11.5 0.044 13.1 4.5 1.7 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Mucin PF01456.12 KFH45641.1 - 0.58 9.9 19.6 0.97 9.2 13.6 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein MSP1_C PF07462.6 KFH45641.1 - 0.61 8.4 2.9 0.73 8.1 2.0 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus bZIP_Maf PF03131.12 KFH45641.1 - 5.2 7.4 13.3 0.088 13.1 3.8 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor Beach PF02138.13 KFH45642.1 - 5.6e-108 360.4 0.0 1.3e-107 359.3 0.0 1.7 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 KFH45642.1 - 2.8e-12 46.4 0.1 5.7e-12 45.4 0.1 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.1 KFH45642.1 - 1.2e-10 41.8 0.1 2.6e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.27 KFH45642.1 - 3e-08 33.2 6.3 0.012 15.4 0.2 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Ubiquitin_2 PF14560.1 KFH45643.1 - 0.00045 20.4 0.0 4.2 7.7 0.0 3.3 3 0 0 3 3 3 2 Ubiquitin-like domain CK2S PF15011.1 KFH45643.1 - 0.04 13.7 0.0 0.08 12.7 0.0 1.5 1 0 0 1 1 1 0 Casein Kinase 2 substrate DUF3407 PF11887.3 KFH45643.1 - 0.046 13.0 0.1 0.046 13.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3407) NPV_P10 PF05531.7 KFH45643.1 - 0.063 13.5 3.0 43 4.4 0.0 4.3 5 1 0 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF1799 PF08809.6 KFH45643.1 - 0.17 11.7 0.1 32 4.4 0.0 3.0 2 1 1 3 3 3 0 Phage related hypothetical protein (DUF1799) NIF PF03031.13 KFH45644.1 - 5.7e-29 100.8 0.6 1.2e-28 99.8 0.0 1.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 KFH45644.1 - 1.3e-09 37.8 0.2 4.1e-09 36.1 0.0 2.0 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 KFH45644.1 - 8.2e-09 35.5 0.0 4.5e-08 33.1 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Biotin_lipoyl PF00364.17 KFH45644.1 - 0.033 13.8 0.0 0.95 9.1 0.0 2.4 2 0 0 2 2 2 0 Biotin-requiring enzyme Ribosomal_S2 PF00318.15 KFH45644.1 - 0.083 12.0 0.0 0.21 10.7 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein S2 DDOST_48kD PF03345.9 KFH45645.1 - 2.1e-157 523.9 0.0 2.4e-157 523.8 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta adh_short PF00106.20 KFH45646.1 - 1.6e-13 50.8 0.1 3.1e-13 49.9 0.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KFH45646.1 - 2.3e-07 30.6 0.0 1e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 KFH45646.1 - 5.2e-07 29.8 0.0 1.2e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 KFH45646.1 - 2.7e-06 26.9 0.0 4.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KFH45646.1 - 8.9e-05 21.5 0.0 0.046 12.6 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein Saccharop_dh PF03435.13 KFH45646.1 - 0.0076 15.2 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 KFH45646.1 - 0.017 14.0 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 KFH45646.1 - 0.035 13.8 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Semialdhyde_dh PF01118.19 KFH45646.1 - 0.11 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Pkinase PF00069.20 KFH45647.1 - 6.2e-40 136.9 0.0 2.4e-38 131.7 0.0 3.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH45647.1 - 5.6e-13 48.5 0.0 5.6e-08 32.1 0.0 3.2 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KFH45647.1 - 0.0025 17.6 0.1 0.02 14.6 0.1 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Actino_peptide PF14408.1 KFH45647.1 - 0.016 15.0 0.0 0.064 13.1 0.0 2.0 1 0 0 1 1 1 0 Ribosomally synthesized peptide in actinomycetes Kinase-like PF14531.1 KFH45647.1 - 0.023 13.6 0.0 0.53 9.1 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Pox_Ag35 PF03286.9 KFH45647.1 - 1.2 8.5 6.3 2.3 7.6 4.4 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.9 KFH45647.1 - 1.4 6.8 5.2 1.8 6.4 3.6 1.1 1 0 0 1 1 1 0 CDC45-like protein MIP PF00230.15 KFH45649.1 - 1.5e-47 162.0 12.5 1.8e-47 161.7 8.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein Kinocilin PF15033.1 KFH45649.1 - 0.37 10.3 2.0 1.8 8.0 0.3 2.5 2 1 1 3 3 3 0 Kinocilin protein Siva PF05458.7 KFH45651.1 - 2.2 7.8 11.3 2.1 7.8 7.4 1.3 1 1 0 1 1 1 0 Cd27 binding protein (Siva) zf-rbx1 PF12678.2 KFH45652.1 - 1.4e-06 28.3 0.8 1.4e-06 28.3 0.6 2.1 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KFH45652.1 - 2.6e-05 23.9 7.3 2.6e-05 23.9 5.0 3.3 2 2 0 2 2 2 1 Ring finger domain zf-Apc11 PF12861.2 KFH45652.1 - 0.00025 20.8 1.3 0.00025 20.8 0.9 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 KFH45652.1 - 0.00041 19.9 0.3 0.00041 19.9 0.2 3.4 2 2 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFH45652.1 - 0.00097 18.8 2.1 0.00097 18.8 1.5 3.0 2 2 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFH45652.1 - 0.0057 16.6 3.6 0.0057 16.6 2.5 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFH45652.1 - 0.013 15.1 1.4 0.013 15.1 1.0 2.7 2 1 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFH45652.1 - 0.014 15.2 0.9 0.014 15.2 0.7 3.1 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING Pkinase PF00069.20 KFH45653.1 - 0.0068 15.5 0.0 0.0076 15.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Fer4 PF00037.22 KFH45654.1 - 3.7e-14 51.6 16.4 5.2e-08 32.1 2.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 KFH45654.1 - 3.5e-12 46.5 11.0 5.9e-12 45.7 7.6 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 KFH45654.1 - 1.9e-10 41.3 6.8 0.0002 22.0 0.2 2.5 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 KFH45654.1 - 6.8e-10 38.6 21.9 2.4e-08 33.6 8.4 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 KFH45654.1 - 8.8e-10 38.7 11.0 1.6e-09 37.8 7.7 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 KFH45654.1 - 1.7e-09 37.4 32.5 5.4e-06 26.1 8.8 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_8 PF13183.1 KFH45654.1 - 9.2e-09 35.2 31.4 8.3e-06 25.7 8.5 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 KFH45654.1 - 3.4e-08 32.9 15.0 0.00042 20.0 1.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 KFH45654.1 - 9.6e-08 31.5 17.0 0.0005 19.8 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 KFH45654.1 - 3.6e-06 27.2 10.1 0.00035 20.8 7.7 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_4 PF12800.2 KFH45654.1 - 3.9e-06 26.7 13.1 0.00043 20.3 2.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 KFH45654.1 - 1.1e-05 25.7 9.8 0.0031 17.9 0.6 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 KFH45654.1 - 0.0097 16.2 14.9 0.31 11.4 2.9 2.7 2 1 1 3 3 3 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 KFH45654.1 - 0.014 15.9 12.9 0.31 11.6 1.2 2.9 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.2 KFH45654.1 - 0.035 14.6 17.7 0.15 12.6 2.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 KFH45654.1 - 0.11 12.6 4.9 0.28 11.3 0.1 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain NUDIX PF00293.23 KFH45655.1 - 2.9e-17 62.5 0.2 6.2e-17 61.5 0.0 1.5 2 0 0 2 2 2 1 NUDIX domain p450 PF00067.17 KFH45656.1 - 1e-77 261.6 0.0 1.3e-77 261.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.27 KFH45657.1 - 5.8e-13 48.1 5.9 0.0003 20.5 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat DpnD-PcfM PF14207.1 KFH45657.1 - 0.023 14.4 0.1 0.051 13.3 0.1 1.6 1 0 0 1 1 1 0 DpnD/PcfM-like protein zf-CCCH PF00642.19 KFH45661.1 - 3.8e-10 39.2 8.1 7.5e-05 22.3 1.5 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) OCC1 PF15506.1 KFH45661.1 - 0.065 13.1 1.5 0.69 9.8 0.9 2.5 2 0 0 2 2 2 0 OCC1 family zf-CCCH_2 PF14608.1 KFH45661.1 - 0.12 12.3 17.5 0.22 11.5 3.4 2.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Isy1 PF06246.7 KFH45662.1 - 1.5e-88 296.5 1.9 2e-88 296.0 1.3 1.2 1 0 0 1 1 1 1 Isy1-like splicing family PCMT PF01135.14 KFH45663.1 - 4.1e-55 186.5 0.0 5e-55 186.2 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 KFH45663.1 - 4.8e-07 30.3 0.0 7.7e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH45663.1 - 2.5e-06 27.1 0.0 6.4e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 KFH45663.1 - 2.4e-05 24.0 0.0 4.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFH45663.1 - 0.0002 21.3 0.0 0.00044 20.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 KFH45663.1 - 0.00021 20.4 0.0 0.0003 19.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_11 PF08241.7 KFH45663.1 - 0.0026 18.2 0.0 0.0048 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH45663.1 - 0.0034 17.1 0.0 0.0052 16.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFH45663.1 - 0.014 14.5 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 KFH45663.1 - 0.039 13.9 0.0 0.81 9.6 0.0 2.2 2 0 0 2 2 2 0 FtsJ-like methyltransferase MTS PF05175.9 KFH45663.1 - 0.065 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_9 PF08003.6 KFH45663.1 - 0.097 11.3 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) RrnaAD PF00398.15 KFH45663.1 - 0.18 10.8 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase COesterase PF00135.23 KFH45664.1 - 7.9e-96 321.8 0.0 9.6e-96 321.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFH45664.1 - 6e-08 32.5 0.0 1.5e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFH45664.1 - 8.1e-07 28.4 0.5 1.4e-06 27.7 0.3 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFH45664.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Glyco_hydro_61 PF03443.9 KFH45665.1 - 1.4e-75 253.8 0.4 1.6e-75 253.6 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Aminotran_3 PF00202.16 KFH45666.1 - 3.2e-40 138.0 0.0 1.2e-21 76.9 0.0 2.9 3 1 0 3 3 3 2 Aminotransferase class-III AAA_26 PF13500.1 KFH45666.1 - 4.9e-31 107.8 0.0 8.4e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain PALP PF00291.20 KFH45667.1 - 3.8e-36 124.8 0.5 4.6e-36 124.6 0.4 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Pacs-1 PF10254.4 KFH45668.1 - 0.56 8.7 5.6 0.93 8.0 3.9 1.3 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein Aminotran_1_2 PF00155.16 KFH45670.1 - 3.1e-37 128.3 0.0 3.6e-37 128.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.15 KFH45670.1 - 0.12 10.9 0.0 0.2 10.1 0.0 1.5 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Helicase_C PF00271.26 KFH45671.1 - 4.4e-10 39.2 0.0 7.4e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_4 PF13871.1 KFH45671.1 - 0.033 13.6 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Helicase_C-like Cutinase PF01083.17 KFH45672.1 - 1.4e-43 148.6 0.1 1.8e-43 148.3 0.1 1.1 1 0 0 1 1 1 1 Cutinase Thioesterase PF00975.15 KFH45672.1 - 1.1e-05 25.7 0.0 1.5e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.2 KFH45672.1 - 0.00011 22.0 0.0 0.00016 21.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 KFH45672.1 - 0.0012 18.5 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PE-PPE PF08237.6 KFH45672.1 - 0.0015 18.0 0.1 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.11 KFH45672.1 - 0.0019 17.7 0.0 0.0037 16.7 0.0 1.5 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase PGAP1 PF07819.8 KFH45672.1 - 0.0046 16.5 0.1 0.0066 16.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KFH45672.1 - 0.02 14.7 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.3 KFH45672.1 - 0.024 14.0 0.2 0.034 13.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_9 PF10081.4 KFH45672.1 - 0.028 13.1 0.0 0.037 12.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family DUF676 PF05057.9 KFH45672.1 - 0.092 12.0 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.15 KFH45672.1 - 0.14 11.6 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold ADH_N PF08240.7 KFH45674.1 - 5.3e-22 77.6 0.3 9.7e-22 76.8 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFH45674.1 - 8.2e-21 73.9 0.1 1.6e-20 73.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 KFH45674.1 - 0.0039 16.7 0.1 0.0066 16.0 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_18 PF12847.2 KFH45674.1 - 0.039 14.5 0.0 0.079 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Redoxin PF08534.5 KFH45674.1 - 0.065 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Redoxin zf-4CXXC_R1 PF10497.4 KFH45675.1 - 0.023 14.8 0.4 0.044 13.9 0.3 1.4 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 DUF349 PF03993.7 KFH45675.1 - 0.053 13.6 0.8 0.053 13.6 0.5 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) CN_hydrolase PF00795.17 KFH45676.1 - 1.8e-22 79.6 0.0 2.4e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PAF-AH_p_II PF03403.8 KFH45677.1 - 3e-34 117.9 0.0 1.6e-30 105.6 0.0 2.2 1 1 1 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 KFH45677.1 - 8.1e-09 35.3 0.0 2.5e-08 33.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KFH45677.1 - 4.3e-06 25.8 0.0 0.00012 21.1 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 KFH45677.1 - 3.2e-05 23.9 1.4 3.2e-05 23.9 1.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 KFH45677.1 - 0.0012 17.7 0.0 0.0033 16.2 0.0 1.6 2 0 0 2 2 2 1 Chlorophyllase Hydrolase_4 PF12146.3 KFH45677.1 - 0.013 15.3 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase adh_short_C2 PF13561.1 KFH45678.1 - 2.3e-32 112.6 0.3 2.6e-32 112.4 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFH45678.1 - 6.2e-24 84.7 1.4 8.1e-24 84.4 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH45678.1 - 6.8e-08 32.3 0.3 9.6e-08 31.8 0.2 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KFH45678.1 - 0.024 14.2 0.3 0.037 13.6 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YjeF_N PF03853.10 KFH45678.1 - 0.042 13.4 0.1 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus Transp_cyt_pur PF02133.10 KFH45679.1 - 3.8e-32 111.3 32.7 4e-30 104.7 22.7 2.1 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Peptidase_S8 PF00082.17 KFH45680.1 - 2.7e-51 174.3 7.9 3.9e-51 173.8 5.5 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KFH45680.1 - 1.9e-19 70.0 0.1 4.9e-19 68.6 0.1 1.8 1 0 0 1 1 1 1 Peptidase inhibitor I9 GRAM PF02893.15 KFH45681.1 - 6e-27 92.9 0.3 4e-14 51.8 0.0 3.4 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.15 KFH45681.1 - 6.7e-25 87.4 0.0 1.5e-24 86.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.24 KFH45681.1 - 4.8e-12 46.0 0.0 1.5e-11 44.4 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 KFH45681.1 - 4.5e-06 26.6 0.1 0.00012 22.0 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain UDPGT PF00201.13 KFH45681.1 - 5.9e-05 21.8 0.0 9.9e-05 21.0 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_11 PF15413.1 KFH45681.1 - 0.00044 20.4 0.1 0.0018 18.5 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.1 KFH45681.1 - 0.0021 17.8 0.0 0.0053 16.6 0.0 1.6 1 0 0 1 1 1 1 PH domain AMP-binding PF00501.23 KFH45682.1 - 3.7e-79 266.0 0.1 5.5e-79 265.5 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFH45682.1 - 5.6e-05 24.0 0.0 0.00017 22.4 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ABC_membrane PF00664.18 KFH45683.1 - 1.1e-73 248.0 31.9 7.6e-38 130.4 10.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFH45683.1 - 2.3e-69 231.9 0.0 2.8e-33 115.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KFH45683.1 - 2.3e-13 49.8 3.5 3.2e-05 23.2 0.0 4.1 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFH45683.1 - 3.6e-12 46.8 0.0 0.14 12.0 0.0 4.4 4 0 0 4 4 4 4 AAA domain AAA_29 PF13555.1 KFH45683.1 - 7.4e-10 38.2 0.4 0.00024 20.5 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 KFH45683.1 - 6.9e-09 34.8 2.7 0.0056 15.3 0.0 3.8 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 KFH45683.1 - 1.8e-08 34.5 3.6 0.00014 21.8 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 KFH45683.1 - 3.5e-08 32.7 0.1 0.0042 16.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 KFH45683.1 - 7.7e-08 31.6 0.2 0.00048 19.2 0.0 3.2 3 0 0 3 3 3 2 Zeta toxin AAA_22 PF13401.1 KFH45683.1 - 1.2e-07 31.8 0.1 0.025 14.7 0.0 4.0 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 KFH45683.1 - 5.8e-06 25.8 0.2 0.14 11.5 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KFH45683.1 - 4.7e-05 24.1 0.0 0.58 10.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KFH45683.1 - 0.00017 21.4 0.0 0.48 10.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 KFH45683.1 - 0.0002 21.2 0.1 2.6 8.0 0.0 4.0 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 KFH45683.1 - 0.00025 20.6 2.2 2.2 7.8 0.3 4.1 3 1 0 3 3 3 1 AAA domain G-alpha PF00503.15 KFH45683.1 - 0.00027 19.7 0.0 0.38 9.3 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_14 PF13173.1 KFH45683.1 - 0.0009 19.1 0.0 1.1 9.1 0.0 3.7 4 0 0 4 4 4 1 AAA domain APS_kinase PF01583.15 KFH45683.1 - 0.0031 17.1 0.0 2.1 7.9 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_10 PF12846.2 KFH45683.1 - 0.0033 16.9 0.9 2.2 7.6 0.0 3.6 4 0 0 4 4 4 1 AAA-like domain AAA_23 PF13476.1 KFH45683.1 - 0.0041 17.4 0.0 0.6 10.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KFH45683.1 - 0.0051 16.5 0.5 6.7 6.4 0.0 3.3 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KFH45683.1 - 0.0081 15.8 0.0 1.3 8.8 0.0 3.1 2 0 0 2 2 2 1 Part of AAA domain DUF815 PF05673.8 KFH45683.1 - 0.01 14.8 0.0 1.1 8.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) DUF87 PF01935.12 KFH45683.1 - 0.023 14.4 0.3 1.4 8.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 MobB PF03205.9 KFH45683.1 - 0.04 13.6 0.3 15 5.3 0.0 2.9 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 KFH45683.1 - 0.052 13.8 0.0 12 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KFH45683.1 - 0.079 13.4 0.1 18 5.8 0.0 3.3 3 0 0 3 3 3 0 Miro-like protein NACHT PF05729.7 KFH45683.1 - 0.079 12.6 0.5 13 5.3 0.1 2.5 2 0 0 2 2 2 0 NACHT domain VirE PF05272.6 KFH45683.1 - 0.089 12.2 0.0 26 4.2 0.0 3.0 4 0 0 4 4 3 0 Virulence-associated protein E NB-ARC PF00931.17 KFH45683.1 - 0.1 11.4 0.4 7.3 5.3 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain MMR_HSR1 PF01926.18 KFH45683.1 - 0.12 12.3 0.0 14 5.6 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 KFH45683.1 - 0.13 12.4 0.2 7.1 6.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.10 KFH45683.1 - 0.15 10.7 0.0 0.29 9.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_15 PF13175.1 KFH45683.1 - 0.23 10.4 0.0 14 4.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Pkinase PF00069.20 KFH45684.1 - 2.4e-13 49.8 0.0 4.2e-07 29.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFH45684.1 - 0.00011 21.3 0.0 0.03 13.3 0.0 2.9 3 1 0 3 3 3 2 Protein tyrosine kinase Methyltransf_23 PF13489.1 KFH45686.1 - 2.3e-12 46.9 0.0 3.2e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH45686.1 - 3.4e-11 42.9 0.0 4.6e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH45686.1 - 8.9e-10 38.9 0.0 1.5e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFH45686.1 - 3.9e-09 36.5 0.0 6.6e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH45686.1 - 3.6e-08 33.9 0.0 6.1e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH45686.1 - 1.3e-07 31.9 0.0 2e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFH45686.1 - 6.1e-06 25.5 0.0 8.2e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KFH45686.1 - 0.00013 22.2 0.0 0.0002 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 KFH45686.1 - 0.00086 20.1 0.0 0.0019 19.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 KFH45686.1 - 0.0069 15.3 0.0 0.0095 14.8 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PCMT PF01135.14 KFH45686.1 - 0.014 14.9 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_21 PF05050.7 KFH45686.1 - 0.047 13.6 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase FkbM domain FtsJ PF01728.14 KFH45686.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Pkinase PF00069.20 KFH45687.1 - 5.5e-64 215.8 0.0 8.3e-64 215.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH45687.1 - 5.9e-47 159.9 0.0 9.1e-47 159.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH45687.1 - 6e-08 31.9 0.0 5.5e-07 28.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFH45687.1 - 0.0039 16.2 0.0 0.0074 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFH45687.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Nucleos_tra2_C PF07662.8 KFH45688.1 - 1.9e-66 223.5 1.7 1.9e-66 223.5 1.2 2.5 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 KFH45688.1 - 4.5e-23 81.3 0.5 4.5e-23 81.3 0.3 2.5 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus DUF3681 PF12442.3 KFH45688.1 - 0.15 12.2 2.2 0.3 11.2 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3681) Gate PF07670.9 KFH45688.1 - 4.7 7.1 19.3 0.035 14.0 4.3 3.4 4 1 0 4 4 4 0 Nucleoside recognition Ribosomal_S2 PF00318.15 KFH45689.1 - 3.3e-47 160.4 0.0 1.2e-46 158.5 0.0 2.0 2 1 0 2 2 2 1 Ribosomal protein S2 MMtag PF10159.4 KFH45689.1 - 6.2 6.9 11.4 6.9 6.7 0.1 2.9 3 0 0 3 3 3 0 Kinase phosphorylation protein PalH PF08733.5 KFH45690.1 - 0.16 10.8 1.2 0.26 10.1 0.8 1.2 1 0 0 1 1 1 0 PalH/RIM21 GFA PF04828.9 KFH45691.1 - 1.1e-14 54.0 1.8 1.9e-14 53.3 1.3 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF1446 PF07287.6 KFH45693.1 - 1e-123 412.3 0.1 1.2e-123 412.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) LYTB PF02401.13 KFH45693.1 - 0.0082 15.0 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 LytB protein zf-C2H2_jaz PF12171.3 KFH45694.1 - 1.9e-09 37.3 0.3 3.2e-09 36.6 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFH45694.1 - 0.002 18.2 0.1 0.0039 17.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFH45694.1 - 0.0096 15.7 0.8 0.015 15.2 0.0 1.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KFH45694.1 - 0.023 14.8 0.1 0.029 14.4 0.1 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Glycolipid_bind PF06475.6 KFH45694.1 - 0.023 13.8 0.1 0.027 13.6 0.0 1.1 1 0 0 1 1 1 0 Putative glycolipid-binding zf-U1 PF06220.7 KFH45694.1 - 0.063 12.8 0.1 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 U1 zinc finger zf-C2H2_4 PF13894.1 KFH45694.1 - 0.12 12.7 0.2 0.26 11.7 0.2 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger Transferase PF02458.10 KFH45695.1 - 8e-15 54.2 0.0 1.3e-10 40.2 0.0 2.1 2 0 0 2 2 2 2 Transferase family SAPS PF04499.10 KFH45696.1 - 4.7e-192 638.8 0.0 7e-191 634.9 0.0 2.7 3 1 0 3 3 3 1 SIT4 phosphatase-associated protein MFS_1 PF07690.11 KFH45697.1 - 9.8e-16 57.3 55.1 2.7e-14 52.6 30.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GCFC PF07842.7 KFH45698.1 - 6.7e-70 235.5 6.0 7.3e-70 235.4 3.7 1.4 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 KFH45698.1 - 1.9e-13 49.9 4.2 4.3e-13 48.8 2.9 1.7 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.3 KFH45698.1 - 5.4e-11 42.5 10.5 5.4e-11 42.5 7.3 2.4 2 0 0 2 2 2 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.2 KFH45698.1 - 2.5e-08 33.6 5.6 4.6e-07 29.5 1.7 3.5 3 0 0 3 3 3 1 DExH-box splicing factor binding site Sel1 PF08238.7 KFH45699.1 - 1.1e-16 60.8 27.6 8.2e-08 32.6 0.2 7.4 7 0 0 7 7 7 5 Sel1 repeat TPR_1 PF00515.23 KFH45699.1 - 0.12 12.0 0.7 0.71 9.5 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFH45699.1 - 0.18 11.4 2.8 0.83 9.3 0.1 3.0 3 0 0 3 3 3 0 TPR repeat Cellulase PF00150.13 KFH45700.1 - 3e-11 43.0 3.7 1.3e-07 31.0 1.1 2.6 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.14 KFH45700.1 - 0.018 14.4 0.1 0.031 13.6 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 DUF3429 PF11911.3 KFH45701.1 - 1.1e-33 116.1 9.3 1.5e-33 115.7 6.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Ycf1 PF05758.7 KFH45701.1 - 0.013 13.2 3.9 0.019 12.7 2.7 1.2 1 0 0 1 1 1 0 Ycf1 Peptidase_S49_N PF08496.5 KFH45701.1 - 0.04 13.7 5.5 0.074 12.8 3.8 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Herpes_gE PF02480.11 KFH45701.1 - 0.061 11.5 0.2 0.12 10.6 0.1 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Neur_chan_memb PF02932.11 KFH45701.1 - 8.5 6.1 6.0 1.8 8.4 0.9 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region ketoacyl-synt PF00109.21 KFH45702.1 - 4.6e-59 199.9 0.3 1.1e-45 156.1 0.1 2.6 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KFH45702.1 - 4.2e-50 169.9 0.6 4.2e-50 169.9 0.4 2.3 2 0 0 2 2 1 1 KR domain PS-DH PF14765.1 KFH45702.1 - 2.5e-44 151.6 4.1 5.2e-44 150.5 2.8 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KFH45702.1 - 8.9e-43 146.8 0.0 1.4e-41 142.9 0.0 2.4 1 1 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 KFH45702.1 - 3.2e-39 134.5 1.0 3.2e-39 134.5 0.7 3.3 3 0 0 3 3 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KFH45702.1 - 1.5e-33 115.1 0.0 5.1e-33 113.4 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KFH45702.1 - 1e-14 54.8 0.0 3.7e-14 52.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH45702.1 - 2e-11 44.4 0.0 7.3e-09 36.2 0.0 3.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH45702.1 - 4e-11 42.7 0.0 1e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KFH45702.1 - 5.1e-11 42.2 0.1 9.6e-10 38.1 0.0 2.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.7 KFH45702.1 - 2.9e-10 40.5 0.0 1.3e-09 38.4 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KFH45702.1 - 4.8e-10 40.4 0.0 8.2e-09 36.4 0.0 3.3 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KFH45702.1 - 3.9e-09 36.4 0.0 2.2e-08 33.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFH45702.1 - 1.7e-08 33.8 0.0 3.8e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.20 KFH45702.1 - 3.6e-08 33.5 0.1 1.5e-07 31.5 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_26 PF13659.1 KFH45702.1 - 8.9e-06 25.7 1.0 0.0007 19.6 0.0 3.9 4 1 0 4 4 4 1 Methyltransferase domain Methyltransf_16 PF10294.4 KFH45702.1 - 0.00027 20.4 0.0 0.00067 19.1 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase ADH_N PF08240.7 KFH45702.1 - 0.0027 17.4 0.0 0.0066 16.1 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_28 PF02636.12 KFH45702.1 - 0.0049 16.3 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_24 PF13578.1 KFH45702.1 - 0.014 16.2 0.2 0.11 13.3 0.0 2.8 2 0 0 2 2 1 0 Methyltransferase domain Nucleoporin_C PF03177.9 KFH45702.1 - 0.42 9.0 0.1 0.65 8.4 0.0 1.1 1 0 0 1 1 1 0 Non-repetitive/WGA-negative nucleoporin C-terminal Coatomer_WDAD PF04053.9 KFH45703.1 - 3.4e-148 494.1 0.0 5.3e-148 493.4 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 KFH45703.1 - 7.8e-86 288.2 0.0 1.1e-85 287.7 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 KFH45703.1 - 2.7e-50 166.5 11.2 1.8e-09 37.1 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 KFH45703.1 - 0.0047 15.1 5.5 0.13 10.3 0.0 3.7 2 1 2 4 4 4 2 Nucleoporin Nup120/160 PAS_9 PF13426.1 KFH45704.1 - 1.1e-32 112.5 0.8 2.5e-19 69.5 0.0 3.8 4 0 0 4 4 4 3 PAS domain PAS_3 PF08447.6 KFH45704.1 - 4.8e-19 68.2 0.0 1.2e-11 44.5 0.0 3.7 3 0 0 3 3 3 3 PAS fold PAS PF00989.19 KFH45704.1 - 5.7e-18 64.7 0.7 3.7e-06 26.7 0.0 4.7 4 1 0 4 4 4 3 PAS fold GATA PF00320.22 KFH45704.1 - 6.5e-15 54.1 9.1 1.3e-14 53.1 6.3 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_11 PF14598.1 KFH45704.1 - 7.4e-10 38.7 2.2 0.00069 19.5 0.0 3.4 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.5 KFH45704.1 - 1e-05 25.5 0.9 0.18 11.8 0.0 3.7 4 0 0 4 4 4 2 PAS fold Pro-rich_19 PF15455.1 KFH45704.1 - 0.0019 17.2 0.2 0.0019 17.2 0.2 2.4 2 0 0 2 2 2 1 Proline-rich 19 ATP-synt_E PF05680.7 KFH45704.1 - 2.6 8.0 8.8 6.4 6.8 6.1 1.7 1 0 0 1 1 1 0 ATP synthase E chain DUF1767 PF08585.7 KFH45707.1 - 3.3e-06 27.2 0.1 5.2e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) CBS PF00571.23 KFH45708.1 - 1.6e-20 72.6 2.5 1.6e-06 27.7 0.1 5.6 5 0 0 5 5 5 5 CBS domain AIM24 PF01987.12 KFH45709.1 - 5.1e-48 163.3 0.0 6.5e-48 163.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF4402 PF14352.1 KFH45709.1 - 0.095 13.1 0.3 0.28 11.6 0.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4402) DUF563 PF04577.9 KFH45710.1 - 7.4e-25 88.0 0.0 1.2e-24 87.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) CRAL_TRIO PF00650.15 KFH45711.1 - 1.1e-45 154.9 0.0 6.1e-45 152.5 0.0 1.9 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KFH45711.1 - 1.8e-14 53.6 0.0 1.8e-14 53.6 0.0 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KFH45711.1 - 4.4e-13 49.3 0.0 7.5e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Adaptin_N PF01602.15 KFH45714.1 - 4.9e-146 487.1 2.8 6.9e-146 486.6 2.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KFH45714.1 - 3.5e-26 92.1 0.1 2.3e-25 89.4 0.0 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KFH45714.1 - 5.7e-17 61.7 0.8 5.9e-09 36.0 0.0 5.0 2 1 3 6 6 6 4 HEAT repeats HEAT PF02985.17 KFH45714.1 - 8.8e-12 44.0 4.5 0.012 15.6 0.0 5.7 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 KFH45714.1 - 8.3e-06 26.1 1.8 0.92 10.0 0.0 5.6 5 1 1 6 6 6 1 HEAT-like repeat UNC45-central PF11701.3 KFH45714.1 - 6.2e-05 22.6 0.1 0.17 11.5 0.0 2.6 2 1 0 2 2 2 2 Myosin-binding striated muscle assembly central Arm PF00514.18 KFH45714.1 - 0.023 14.5 0.8 2.6 7.9 0.0 4.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat RasGEF_N_2 PF14663.1 KFH45714.1 - 0.059 13.3 0.1 1.5 8.8 0.0 3.1 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain CLASP_N PF12348.3 KFH45714.1 - 0.07 12.4 0.0 2 7.7 0.0 2.9 2 1 1 3 3 3 0 CLASP N terminal Utp12 PF04003.7 KFH45714.1 - 0.5 10.2 2.8 4.7 7.1 0.1 3.1 3 0 0 3 3 3 0 Dip2/Utp12 Family Glucan_synthase PF02364.10 KFH45715.1 - 0 1453.9 0.0 0 1453.2 0.0 1.4 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 KFH45715.1 - 1.2e-40 138.0 0.2 2.7e-40 136.9 0.1 1.6 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 NIF3 PF01784.13 KFH45716.1 - 3.3e-56 190.5 0.0 4.2e-56 190.2 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) DUF2434 PF10361.4 KFH45717.1 - 3.9e-115 383.9 7.3 4.9e-115 383.6 5.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) Acetyltransf_1 PF00583.19 KFH45718.1 - 1.1e-08 35.0 0.0 1.9e-08 34.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KFH45718.1 - 9.7e-08 31.9 0.0 0.0019 18.0 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KFH45718.1 - 8.8e-07 29.0 0.0 2.8e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFH45718.1 - 1.5e-06 28.3 0.0 1.4e-05 25.1 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFH45718.1 - 0.0027 17.4 0.0 0.0046 16.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein DUF3749 PF12568.3 KFH45718.1 - 0.0029 17.1 0.0 0.0044 16.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KFH45718.1 - 0.0084 15.9 0.0 0.02 14.8 0.0 1.6 1 1 1 2 2 2 1 GCN5-related N-acetyl-transferase DUF2656 PF10847.3 KFH45718.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2656) PCI_Csn8 PF10075.4 KFH45719.1 - 8.5e-35 119.6 0.0 1.2e-34 119.1 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 KFH45719.1 - 4.8e-19 68.7 0.1 6.7e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Cpn60_TCP1 PF00118.19 KFH45722.1 - 2.1e-146 488.3 0.6 2.5e-146 488.0 0.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PDCD2_C PF04194.8 KFH45722.1 - 1.5e-50 170.9 0.7 2.9e-50 170.0 0.0 1.8 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain Fer4_12 PF13353.1 KFH45722.1 - 0.078 13.1 0.0 12 6.0 0.0 2.7 2 0 0 2 2 2 0 4Fe-4S single cluster domain Exo_endo_phos PF03372.18 KFH45724.1 - 4.9e-13 49.5 0.4 5.9e-13 49.3 0.2 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KFH45724.1 - 0.004 16.7 0.0 0.0074 15.8 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF2985 PF11204.3 KFH45725.1 - 2.6e-28 97.5 4.4 4.6e-28 96.7 3.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) zf-H2C2 PF09337.5 KFH45726.1 - 5.3e-23 80.1 3.9 1.4e-22 78.8 2.7 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_4 PF13420.1 KFH45726.1 - 0.00026 20.9 0.0 0.00051 20.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFH45726.1 - 0.0092 15.9 0.0 0.024 14.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Zip PF02535.17 KFH45726.1 - 1.7 7.6 15.6 2.8 6.8 10.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter PAT1 PF09770.4 KFH45726.1 - 6.8 4.7 15.3 11 4.1 10.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Gelsolin PF00626.17 KFH45728.1 - 4.9e-31 106.2 0.1 1.6e-11 43.7 0.0 3.2 3 0 0 3 3 3 3 Gelsolin repeat Cpn60_TCP1 PF00118.19 KFH45729.1 - 3.7e-141 471.0 4.1 4.2e-141 470.8 2.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DASH_Dam1 PF08653.5 KFH45730.1 - 1.4e-28 98.4 1.9 1.8e-28 98.0 1.3 1.1 1 0 0 1 1 1 1 DASH complex subunit Dam1 RHIM PF12721.2 KFH45730.1 - 0.37 11.2 0.1 0.37 11.2 0.1 2.3 2 1 1 3 3 3 0 RIP homotypic interaction motif Thioesterase PF00975.15 KFH45731.1 - 1.5e-11 44.9 0.1 5.3e-08 33.3 0.0 2.7 2 1 0 2 2 2 2 Thioesterase domain Abhydrolase_6 PF12697.2 KFH45731.1 - 0.00014 21.8 0.1 0.00016 21.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH45731.1 - 0.00063 19.5 0.0 0.00085 19.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KFH45731.1 - 0.023 14.2 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KFH45731.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Aconitase PF00330.15 KFH45732.1 - 3e-172 573.3 0.0 9.2e-172 571.6 0.0 1.7 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KFH45732.1 - 7.9e-45 152.1 0.0 1.3e-44 151.4 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain I-set PF07679.11 KFH45732.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain Propep_M14 PF02244.11 KFH45732.1 - 0.14 11.8 0.0 0.51 10.0 0.0 2.0 1 0 0 1 1 1 0 Carboxypeptidase activation peptide GFA PF04828.9 KFH45733.1 - 0.00065 19.5 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Peptidase_S8 PF00082.17 KFH45734.1 - 1e-17 64.2 3.1 1.1e-10 41.0 0.5 3.1 1 1 2 3 3 3 3 Subtilase family Inhibitor_I9 PF05922.11 KFH45734.1 - 6e-05 23.5 0.0 0.00058 20.3 0.0 2.4 2 1 0 2 2 2 1 Peptidase inhibitor I9 p450 PF00067.17 KFH45735.1 - 1.4e-57 195.2 0.0 2e-57 194.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 HEAT_2 PF13646.1 KFH45736.1 - 1.3e-06 28.6 0.1 0.023 14.9 0.0 3.9 3 2 0 3 3 3 2 HEAT repeats CLASP_N PF12348.3 KFH45736.1 - 1.7e-06 27.6 0.0 1.4e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 CLASP N terminal HEAT PF02985.17 KFH45736.1 - 0.00063 19.6 0.0 0.51 10.5 0.0 4.6 6 0 0 6 6 6 1 HEAT repeat TPR_MLP1_2 PF07926.7 KFH45736.1 - 0.0065 16.2 1.2 0.0065 16.2 0.8 2.1 3 0 0 3 3 3 1 TPR/MLP1/MLP2-like protein IncA PF04156.9 KFH45736.1 - 0.013 15.1 2.4 0.037 13.6 1.7 1.7 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 KFH45736.1 - 0.027 13.5 8.1 0.057 12.4 5.6 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Cnd1 PF12717.2 KFH45736.1 - 0.037 13.8 0.0 0.096 12.5 0.0 1.6 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 MAP65_ASE1 PF03999.7 KFH45736.1 - 0.038 12.5 4.4 0.06 11.9 3.1 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) TAN PF11640.3 KFH45736.1 - 0.088 12.5 0.0 0.7 9.6 0.0 2.3 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair Baculo_PEP_C PF04513.7 KFH45736.1 - 0.93 9.3 4.5 16 5.2 1.4 3.2 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF972 PF06156.8 KFH45736.1 - 1.1 9.6 6.2 13 6.2 4.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) HALZ PF02183.13 KFH45736.1 - 1.4 8.6 7.2 4.1 7.1 0.9 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper TBPIP PF07106.8 KFH45736.1 - 4.5 6.8 8.8 4.7 6.7 4.6 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) UDP-g_GGTase PF06427.6 KFH45737.1 - 2e-58 197.1 0.0 4.4e-58 196.0 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 KFH45737.1 - 7.8e-05 22.1 0.8 0.00024 20.5 0.5 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 8 DUF1162 PF06650.7 KFH45738.1 - 2.5e-89 299.1 0.2 3.7e-87 292.0 0.0 3.4 3 1 0 3 3 3 1 Protein of unknown function (DUF1162) Chorein_N PF12624.2 KFH45738.1 - 5.5e-42 142.0 0.1 1.9e-41 140.3 0.0 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 KFH45738.1 - 1.6e-05 24.9 0.1 7.8e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 ATG C terminal domain TPR_11 PF13414.1 KFH45739.1 - 5.3e-41 138.1 43.7 1.2e-06 28.0 0.0 12.3 9 3 1 12 12 12 8 TPR repeat TPR_16 PF13432.1 KFH45739.1 - 2.7e-30 104.3 54.5 0.00064 20.3 0.0 14.1 10 4 3 14 14 14 7 Tetratricopeptide repeat TPR_14 PF13428.1 KFH45739.1 - 2.5e-26 89.7 37.3 0.014 15.9 0.1 15.5 13 4 4 17 17 15 8 Tetratricopeptide repeat TPR_17 PF13431.1 KFH45739.1 - 4.5e-26 88.8 15.3 0.067 13.4 0.0 16.2 18 0 0 18 18 18 5 Tetratricopeptide repeat TPR_1 PF00515.23 KFH45739.1 - 4.5e-24 83.0 27.8 0.00033 20.1 0.0 13.3 14 0 0 14 14 14 7 Tetratricopeptide repeat TPR_2 PF07719.12 KFH45739.1 - 3.2e-22 76.6 53.2 0.013 15.4 0.3 15.4 17 0 0 17 17 15 7 Tetratricopeptide repeat TPR_19 PF14559.1 KFH45739.1 - 8.1e-22 77.3 30.0 0.0022 18.2 0.1 11.7 9 5 3 12 12 12 6 Tetratricopeptide repeat TPR_8 PF13181.1 KFH45739.1 - 5.9e-16 56.9 14.4 0.2 11.4 0.0 11.6 10 1 1 11 11 11 4 Tetratricopeptide repeat TPR_12 PF13424.1 KFH45739.1 - 2.6e-15 56.1 49.6 0.00041 20.2 0.0 12.3 7 5 8 15 15 14 8 Tetratricopeptide repeat TPR_7 PF13176.1 KFH45739.1 - 2.4e-12 45.6 26.8 0.11 12.3 0.2 12.1 12 1 1 13 13 12 4 Tetratricopeptide repeat TPR_9 PF13371.1 KFH45739.1 - 6.1e-09 35.6 11.3 0.00083 19.1 0.3 6.4 6 1 0 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 KFH45739.1 - 3e-08 33.6 20.2 0.031 14.3 0.0 6.9 6 1 0 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 KFH45739.1 - 0.00093 19.2 13.6 8.3 6.6 0.3 6.6 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFH45739.1 - 0.0032 17.8 31.1 16 6.2 0.0 13.7 16 0 0 16 16 16 0 Tetratricopeptide repeat HemY_N PF07219.8 KFH45739.1 - 0.018 14.6 11.3 0.067 12.7 0.0 5.2 5 0 0 5 5 5 0 HemY protein N-terminus HEAT PF02985.17 KFH45740.1 - 1.1e-15 56.1 20.5 0.01 15.8 0.0 11.8 14 0 0 14 14 10 4 HEAT repeat HEAT_2 PF13646.1 KFH45740.1 - 2.7e-14 53.2 21.2 3e-07 30.6 0.1 8.5 6 3 3 9 9 8 4 HEAT repeats HEAT_EZ PF13513.1 KFH45740.1 - 2e-13 50.3 19.4 1.3e-07 31.8 0.3 9.4 6 2 2 9 9 9 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KFH45740.1 - 8.3e-11 42.1 0.9 0.076 13.4 0.0 7.6 3 3 5 9 9 9 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 KFH45740.1 - 1.1e-08 34.1 1.0 3e-06 26.2 0.1 4.2 3 1 1 4 4 4 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.3 KFH45740.1 - 3.1e-08 33.2 3.8 0.054 12.8 0.1 6.1 4 2 1 5 5 5 1 CLASP N terminal RIX1 PF08167.7 KFH45740.1 - 3.4e-08 33.3 0.5 0.002 17.8 0.0 5.4 3 2 2 5 5 5 1 rRNA processing/ribosome biogenesis CAS_CSE1 PF03378.10 KFH45740.1 - 0.00018 19.9 1.3 1.7 6.8 0.0 4.2 4 1 0 4 4 4 2 CAS/CSE protein, C-terminus SEN1_N PF12726.2 KFH45740.1 - 0.00031 18.9 0.4 0.017 13.1 0.0 2.6 2 0 0 2 2 2 1 SEN1 N terminal Cnd1 PF12717.2 KFH45740.1 - 0.0039 17.0 3.1 5.7 6.7 0.0 5.0 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_N PF03224.9 KFH45740.1 - 0.0094 15.0 7.6 0.2 10.7 0.1 3.3 2 1 0 3 3 3 2 V-ATPase subunit H IBN_N PF03810.14 KFH45740.1 - 0.014 15.3 0.5 0.18 11.7 0.1 3.2 1 1 1 2 2 2 0 Importin-beta N-terminal domain TFCD_C PF12612.3 KFH45740.1 - 0.016 14.6 1.5 0.28 10.5 0.0 3.7 4 1 1 5 5 5 0 Tubulin folding cofactor D C terminal DRIM PF07539.7 KFH45740.1 - 0.062 12.7 1.8 0.26 10.6 0.5 2.6 3 0 0 3 3 3 0 Down-regulated in metastasis FdhE PF04216.7 KFH45740.1 - 2 8.0 18.3 0.056 13.1 0.7 4.2 4 2 0 4 4 4 0 Protein involved in formate dehydrogenase formation CBS PF00571.23 KFH45741.1 - 6.5e-40 134.6 13.0 4.5e-11 42.3 0.0 5.3 6 0 0 6 6 6 4 CBS domain PB1 PF00564.19 KFH45741.1 - 3.7e-09 36.1 0.0 1.2e-08 34.4 0.0 1.9 2 0 0 2 2 2 1 PB1 domain Nha1_C PF08619.5 KFH45741.1 - 0.0092 15.2 5.4 0.061 12.5 0.0 2.2 2 0 0 2 2 2 2 Alkali metal cation/H+ antiporter Nha1 C terminus Sugar_tr PF00083.19 KFH45742.1 - 1.7e-68 231.2 11.8 2.3e-68 230.8 8.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH45742.1 - 1.5e-14 53.5 29.2 1.5e-14 53.5 20.3 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily HxlR PF01638.12 KFH45743.1 - 0.012 15.2 0.1 20 4.9 0.0 3.2 3 0 0 3 3 3 0 HxlR-like helix-turn-helix Kinesin PF00225.18 KFH45744.1 - 2.3e-82 276.3 0.0 3.5e-82 275.8 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain zf-H2C2_2 PF13465.1 KFH45745.1 - 5.9e-11 42.0 8.8 5.4e-05 23.2 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFH45745.1 - 2e-08 34.1 18.7 0.0016 18.6 1.9 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFH45745.1 - 0.004 17.3 14.5 0.29 11.5 0.2 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFH45745.1 - 0.026 14.4 6.3 1.2 9.1 0.5 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger BolA PF01722.13 KFH45746.1 - 1.3e-21 76.3 0.0 1.5e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein Aminotran_1_2 PF00155.16 KFH45747.1 - 1.5e-33 116.3 0.0 1.7e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KFH45747.1 - 0.013 13.7 0.0 0.022 13.0 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Mog1 PF04603.7 KFH45748.1 - 1.3e-18 67.2 0.0 2.2e-18 66.5 0.0 1.3 1 1 0 1 1 1 1 Ran-interacting Mog1 protein Vps51 PF08700.6 KFH45749.1 - 3e-29 100.6 0.0 5.5e-29 99.8 0.0 1.4 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.4 KFH45749.1 - 0.0028 17.6 0.1 0.0044 16.9 0.1 1.3 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Dor1 PF04124.7 KFH45749.1 - 0.003 16.0 0.1 0.0039 15.7 0.1 1.1 1 0 0 1 1 1 1 Dor1-like family Vps53_N PF04100.7 KFH45749.1 - 0.28 9.9 0.0 0.28 9.9 0.0 1.4 2 0 0 2 2 2 0 Vps53-like, N-terminal DUF4106 PF13388.1 KFH45749.1 - 3.7 6.3 5.6 5.5 5.8 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) CAP_N PF01213.14 KFH45749.1 - 9.2 5.4 8.2 17 4.5 5.7 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SprT-like PF10263.4 KFH45750.1 - 1.3e-52 177.5 5.2 2.2e-52 176.8 3.6 1.3 1 0 0 1 1 1 1 SprT-like family HMG_box PF00505.14 KFH45750.1 - 0.00015 21.9 0.1 0.00046 20.4 0.1 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box Zn-ribbon_8 PF09723.5 KFH45750.1 - 0.004 17.0 1.7 0.0096 15.8 1.2 1.6 1 0 0 1 1 1 1 Zinc ribbon domain YABBY PF04690.8 KFH45750.1 - 0.0047 17.1 2.5 0.008 16.4 0.1 2.4 2 0 0 2 2 2 1 YABBY protein CHDNT PF08073.7 KFH45750.1 - 0.022 14.4 0.1 0.051 13.2 0.0 1.6 1 0 0 1 1 1 0 CHDNT (NUC034) domain XFP_N PF09364.5 KFH45751.1 - 4.8e-174 578.3 0.0 6.4e-174 577.9 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.5 KFH45751.1 - 3.6e-82 274.7 0.0 5.2e-82 274.1 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.10 KFH45751.1 - 3.6e-80 267.7 0.0 8.6e-80 266.5 0.0 1.7 2 0 0 2 2 2 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase DUF2962 PF11176.3 KFH45751.1 - 0.12 11.9 0.0 0.3 10.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2962) DNA_ligase_A_M PF01068.16 KFH45752.1 - 5e-49 166.4 0.1 1.7e-46 158.1 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KFH45752.1 - 7.6e-40 136.5 0.0 1.3e-39 135.7 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KFH45752.1 - 6e-20 71.4 0.2 3.6e-19 68.9 0.0 2.5 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region SAC3_GANP PF03399.11 KFH45753.1 - 7.7e-26 90.9 0.0 1.1e-25 90.4 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KFH45753.1 - 1.9e-21 76.3 0.0 5.2e-21 74.9 0.0 1.7 2 1 1 3 3 3 1 COP9 signalosome, subunit CSN8 COG5 PF10392.4 KFH45754.1 - 3.8e-37 127.1 2.0 8.4e-37 126.0 0.2 2.4 3 0 0 3 3 3 1 Golgi transport complex subunit 5 SPX PF03105.14 KFH45754.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 SPX domain DUF4470 PF14737.1 KFH45756.1 - 2.6e-20 72.0 0.0 5.8e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 KFH45756.1 - 4.8e-12 45.5 13.6 1.1e-11 44.4 9.4 1.6 1 0 0 1 1 1 1 MYND finger PAP2 PF01569.16 KFH45757.1 - 6.6e-18 64.6 0.3 6.6e-18 64.6 0.2 2.3 2 2 0 2 2 2 1 PAP2 superfamily AIRC PF00731.15 KFH45758.1 - 3.4e-59 198.4 1.1 7.1e-59 197.3 0.7 1.6 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 KFH45758.1 - 3.4e-50 169.7 0.0 5.3e-50 169.1 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 KFH45758.1 - 3.7e-13 49.6 0.1 7.9e-13 48.5 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KFH45758.1 - 0.00016 21.1 0.0 0.00059 19.2 0.0 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus XdhC_C PF13478.1 KFH45758.1 - 0.0006 20.1 0.1 0.26 11.5 0.0 2.7 2 1 0 2 2 2 2 XdhC Rossmann domain ATPgrasp_Ter PF15632.1 KFH45758.1 - 0.0067 15.2 0.0 0.03 13.0 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon 2-Hacid_dh_C PF02826.14 KFH45758.1 - 0.047 12.8 0.0 0.094 11.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain zf-C2H2_4 PF13894.1 KFH45760.1 - 3.8e-06 26.8 7.8 0.00031 20.8 0.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KFH45760.1 - 0.0004 20.5 12.3 0.0034 17.6 0.3 2.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFH45760.1 - 0.0028 17.8 1.5 0.0028 17.8 1.0 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.2 KFH45760.1 - 0.028 14.6 5.6 0.41 10.9 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-TRAF PF02176.13 KFH45760.1 - 0.26 11.6 4.3 0.75 10.2 0.3 2.3 1 1 1 2 2 2 0 TRAF-type zinc finger Choline_kinase PF01633.15 KFH45761.1 - 7.5e-50 169.4 0.0 4.2e-49 166.9 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 KFH45761.1 - 7.6e-13 48.7 1.8 7.6e-13 48.7 1.2 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 KFH45761.1 - 0.00059 19.0 0.0 0.0017 17.5 0.0 1.7 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 KFH45761.1 - 0.00094 17.9 0.0 0.0012 17.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) 14-3-3 PF00244.15 KFH45762.1 - 1.6e-113 377.6 2.2 2.1e-113 377.2 1.5 1.1 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 KFH45762.1 - 0.015 15.2 1.0 6.9 6.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat SYCE1 PF15233.1 KFH45762.1 - 0.084 12.8 1.0 0.31 10.9 0.1 2.1 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 Fungal_trans PF04082.13 KFH45763.1 - 4.5e-22 78.1 0.3 6.9e-22 77.5 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH45763.1 - 7.2e-09 35.4 8.9 1.9e-08 34.1 6.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 KFH45764.1 - 0.015 15.5 0.1 0.015 15.5 0.0 7.4 7 0 0 7 7 7 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KFH45764.1 - 8.9 6.8 35.5 0.91 10.0 0.1 7.1 7 0 0 7 7 7 0 Zinc finger, C2H2 type SBDS PF01172.13 KFH45765.1 - 1.3e-23 82.5 0.0 1.5e-23 82.3 0.0 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein MbtH PF03621.8 KFH45765.1 - 0.032 13.6 0.0 0.061 12.6 0.0 1.4 1 0 0 1 1 1 0 MbtH-like protein Glyoxalase_2 PF12681.2 KFH45765.1 - 0.096 13.3 0.1 0.27 11.8 0.0 1.7 1 1 1 2 2 2 0 Glyoxalase-like domain SYF2 PF08231.7 KFH45765.1 - 0.13 12.3 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 SYF2 splicing factor Pkinase PF00069.20 KFH45766.1 - 6.1e-61 205.8 0.0 3.7e-39 134.4 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFH45766.1 - 3.9e-27 94.9 0.0 1.8e-20 73.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 KFH45766.1 - 8.6e-14 51.5 0.0 1.8e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 KFH45766.1 - 1.5e-07 30.6 0.1 2.3e-05 23.5 0.0 2.5 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 KFH45766.1 - 5.4e-06 26.3 0.0 0.0041 16.8 0.1 2.8 1 1 0 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KFH45766.1 - 0.02 13.7 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 KFH45766.1 - 0.025 13.6 0.0 0.053 12.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L35Ae PF01247.13 KFH45767.1 - 2.3e-40 136.2 0.4 2.9e-40 135.9 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 KFH45767.1 - 8.7e-05 22.3 0.1 0.041 13.8 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain Acetate_kinase PF00871.12 KFH45768.1 - 4.3e-90 302.0 0.0 5.1e-90 301.8 0.0 1.1 1 0 0 1 1 1 1 Acetokinase family RIC1 PF07064.8 KFH45769.1 - 6.2e-84 281.4 0.2 8.6e-84 281.0 0.2 1.2 1 0 0 1 1 1 1 RIC1 WD40 PF00400.27 KFH45769.1 - 0.00018 21.2 0.7 3.4 7.7 0.0 4.4 5 0 0 5 5 5 2 WD domain, G-beta repeat Ubiq-Cytc-red_N PF09165.5 KFH45769.1 - 0.066 13.5 2.6 24 5.3 0.1 3.6 3 0 0 3 3 3 0 Ubiquinol-cytochrome c reductase 8 kDa, N-terminal Coatomer_WDAD PF04053.9 KFH45769.1 - 0.11 11.2 0.0 0.19 10.4 0.0 1.3 1 0 0 1 1 1 0 Coatomer WD associated region Med14 PF08638.6 KFH45770.1 - 5.7e-69 231.2 0.0 9.5e-69 230.5 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 Lin-8 PF03353.10 KFH45770.1 - 1 8.5 6.6 1.7 7.8 4.6 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist zf-CCCH_2 PF14608.1 KFH45771.1 - 2.6e-09 36.6 60.5 7.9e-06 25.6 8.8 5.4 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type Nab2 PF11517.3 KFH45771.1 - 0.0044 17.0 0.0 0.008 16.2 0.0 1.3 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Sporozoite_P67 PF05642.6 KFH45771.1 - 0.0092 13.9 0.0 0.02 12.7 0.0 1.4 1 1 0 1 1 1 1 Sporozoite P67 surface antigen Pkinase PF00069.20 KFH45772.1 - 5.6e-60 202.6 0.0 1.5e-59 201.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH45772.1 - 4.5e-35 120.9 0.0 7.3e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH45772.1 - 9.7e-06 24.7 0.0 1.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like POLO_box PF00659.13 KFH45772.1 - 0.00029 20.7 0.1 0.28 11.1 0.0 2.9 2 0 0 2 2 2 2 POLO box duplicated region Kdo PF06293.9 KFH45772.1 - 0.0014 17.6 0.0 0.0029 16.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Proteasome PF00227.21 KFH45773.1 - 3.9e-39 133.9 0.0 4.7e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit SH3_3 PF08239.6 KFH45774.1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial SH3 domain Aminotran_1_2 PF00155.16 KFH45775.1 - 3.1e-16 59.2 0.0 4.1e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KFH45775.1 - 4.6e-07 28.7 0.0 8e-07 27.9 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.12 KFH45775.1 - 0.042 12.8 0.0 0.38 9.7 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Ribosomal_L36e PF01158.13 KFH45776.1 - 3e-40 136.1 5.3 3.4e-40 135.9 3.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e LemA PF04011.7 KFH45776.1 - 0.018 14.1 0.1 0.021 13.9 0.1 1.1 1 0 0 1 1 1 0 LemA family PRA-PH PF01503.12 KFH45776.1 - 0.056 13.7 0.0 0.85 9.9 0.0 2.0 1 1 1 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase La PF05383.12 KFH45777.1 - 1.6e-14 53.4 0.0 2.4e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 La domain Lipase_3 PF01764.20 KFH45778.1 - 5.7e-32 110.2 0.0 7.7e-32 109.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 KFH45778.1 - 6.5e-05 22.9 0.0 9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH45778.1 - 8e-05 22.4 0.0 9.8e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KFH45778.1 - 0.00019 21.7 0.0 0.00032 20.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.15 KFH45778.1 - 0.0014 18.2 0.0 0.0099 15.4 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2974 PF11187.3 KFH45778.1 - 0.003 16.9 0.0 0.064 12.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Esterase PF00756.15 KFH45778.1 - 0.02 14.3 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase PGAP1 PF07819.8 KFH45778.1 - 0.055 13.0 0.0 0.084 12.4 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF900 PF05990.7 KFH45778.1 - 0.17 11.1 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Cutinase PF01083.17 KFH45778.1 - 0.17 11.6 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Cutinase DUF533 PF04391.7 KFH45779.1 - 0.78 9.0 22.1 1.8 7.9 0.6 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF533) SR-25 PF10500.4 KFH45780.1 - 0.0017 17.8 2.4 0.0028 17.1 1.6 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Dehydrin PF00257.14 KFH45780.1 - 0.016 15.5 0.0 0.022 15.0 0.0 1.2 1 0 0 1 1 1 0 Dehydrin CAF-1_p60_C PF15512.1 KFH45780.1 - 0.42 11.0 8.2 0.61 10.5 5.7 1.2 1 0 0 1 1 1 0 Chromatin assembly factor complex 1 subunit p60, C-terminal Equine_IAV_S2 PF06502.6 KFH45780.1 - 0.72 9.7 2.4 1.6 8.6 1.6 1.5 1 0 0 1 1 1 0 Equine infectious anaemia virus S2 protein ADH_N PF08240.7 KFH45781.1 - 1.3e-26 92.4 0.7 2.5e-26 91.5 0.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFH45781.1 - 4.8e-15 55.2 0.1 1.2e-14 54.0 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFH45781.1 - 3.5e-05 24.7 0.0 7.1e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 3HCDH_N PF02737.13 KFH45781.1 - 0.014 15.0 0.1 0.021 14.4 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain D-ser_dehydrat PF14031.1 KFH45781.1 - 0.06 13.5 0.2 0.17 12.0 0.1 1.9 2 1 0 2 2 2 0 Putative serine dehydratase domain Pyr_redox PF00070.22 KFH45781.1 - 0.43 11.0 2.6 6 7.3 1.1 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Suf PF05843.9 KFH45782.1 - 0.0019 18.0 5.6 0.006 16.3 0.1 2.9 3 1 0 3 3 3 1 Suppressor of forked protein (Suf) TPR_16 PF13432.1 KFH45782.1 - 0.016 15.8 0.0 0.016 15.8 0.0 4.5 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFH45782.1 - 0.21 12.3 11.5 20 6.2 0.0 6.6 7 2 2 9 9 9 0 Tetratricopeptide repeat VMA21 PF09446.5 KFH45783.1 - 8.5e-14 51.2 7.6 1.2e-13 50.7 5.3 1.2 1 0 0 1 1 1 1 VMA21-like domain DUF4282 PF14110.1 KFH45783.1 - 0.2 11.8 5.8 0.26 11.4 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) Fungal_trans PF04082.13 KFH45784.1 - 2e-11 43.2 0.8 3.2e-11 42.5 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH45784.1 - 2.4e-10 40.1 10.0 5e-10 39.1 6.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain peroxidase PF00141.18 KFH45785.1 - 2.1e-51 174.6 0.0 3.3e-51 173.9 0.0 1.3 1 0 0 1 1 1 1 Peroxidase E1-E2_ATPase PF00122.15 KFH45786.1 - 1e-63 214.4 5.8 1.7e-62 210.5 3.7 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFH45786.1 - 4.3e-45 153.4 4.6 4.3e-45 153.4 3.2 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFH45786.1 - 7.3e-31 108.2 0.0 1.2e-29 104.2 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFH45786.1 - 2.3e-21 75.0 0.0 5.4e-21 73.8 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KFH45786.1 - 1.2e-20 73.1 0.0 2.6e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KFH45786.1 - 5.3e-16 59.3 0.1 2.7e-15 57.0 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFH45786.1 - 3.5e-07 30.0 1.1 5.8e-06 26.0 0.5 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase 2TM PF13239.1 KFH45786.1 - 1.5 8.9 5.6 14 5.8 0.1 3.3 3 0 0 3 3 3 0 2TM domain eIF-3_zeta PF05091.7 KFH45787.1 - 1.1e-194 647.8 0.0 1.4e-194 647.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.8 KFH45787.1 - 0.041 13.3 0.0 0.11 11.8 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF569) CDC48_2 PF02933.12 KFH45787.1 - 0.11 12.0 0.0 0.97 9.1 0.0 2.3 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 Ribosomal_L2_C PF03947.13 KFH45788.1 - 1.2e-44 151.2 4.2 8.1e-44 148.5 2.9 2.2 1 1 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KFH45788.1 - 3.2e-26 91.1 0.1 6.7e-26 90.0 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain PEP-utilizers PF00391.18 KFH45788.1 - 0.062 12.8 0.2 0.15 11.6 0.1 1.6 1 0 0 1 1 1 0 PEP-utilising enzyme, mobile domain NPR3 PF03666.8 KFH45789.1 - 1.9e-131 438.7 0.4 2.4e-131 438.3 0.3 1.1 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Chitin_synth_2 PF03142.10 KFH45790.1 - 1.2e-292 971.0 0.1 1.5e-292 970.7 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 KFH45790.1 - 7.9e-18 64.8 0.2 1.9e-17 63.6 0.1 1.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.23 KFH45790.1 - 4.4e-13 48.8 0.1 4.8e-11 42.2 0.0 2.5 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 KFH45790.1 - 3.3e-12 46.7 0.0 2.5e-11 43.8 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KFH45790.1 - 4.5e-05 22.8 0.0 0.00082 18.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KFH45790.1 - 0.017 14.7 0.0 0.12 12.0 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 2 OPA3 PF07047.7 KFH45791.1 - 8.1e-41 138.9 0.6 1.1e-40 138.4 0.4 1.2 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Wbp11 PF09429.5 KFH45791.1 - 0.02 14.8 13.6 0.45 10.5 4.3 2.3 2 0 0 2 2 2 0 WW domain binding protein 11 IncA PF04156.9 KFH45791.1 - 0.034 13.7 5.8 0.073 12.6 4.0 1.5 1 0 0 1 1 1 0 IncA protein Snapin_Pallidin PF14712.1 KFH45791.1 - 0.096 13.0 2.8 0.19 12.0 1.9 1.5 1 0 0 1 1 1 0 Snapin/Pallidin Nbl1_Borealin_N PF10444.4 KFH45791.1 - 0.36 10.2 5.6 5 6.5 2.2 2.3 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal CAF-1_p150 PF11600.3 KFH45791.1 - 0.4 10.0 18.7 1.9 7.8 0.5 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF607 PF04678.8 KFH45791.1 - 0.6 10.0 4.0 0.56 10.0 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF607 FimP PF09766.4 KFH45791.1 - 1.9 7.4 7.8 0.17 10.9 2.1 1.6 2 0 0 2 2 2 0 Fms-interacting protein APG6 PF04111.7 KFH45791.1 - 3.3 6.6 6.2 6 5.8 4.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Med21 PF11221.3 KFH45791.1 - 4 7.3 10.2 1.3 9.0 4.6 1.8 2 0 0 2 2 2 0 Subunit 21 of Mediator complex CK_II_beta PF01214.13 KFH45792.1 - 8e-73 243.8 0.1 9.6e-73 243.6 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Prp31_C PF09785.4 KFH45794.1 - 1.1e-43 148.5 0.6 1.1e-43 148.5 0.4 1.9 2 0 0 2 2 2 1 Prp31 C terminal domain Nop PF01798.13 KFH45794.1 - 6.6e-35 119.6 0.1 1.4e-34 118.5 0.0 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KFH45794.1 - 5.3e-20 70.9 0.0 9.1e-20 70.2 0.0 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain Sugar_tr PF00083.19 KFH45795.1 - 9.4e-21 73.9 21.1 2.6e-14 52.6 4.4 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter DUF3611 PF12263.3 KFH45795.1 - 0.0091 15.4 0.1 0.022 14.1 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3611) RhoGEF PF00621.15 KFH45796.1 - 1.5e-20 73.8 0.0 2.8e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain WD40 PF00400.27 KFH45797.1 - 2.3e-30 103.3 7.8 5.8e-08 32.3 0.1 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 KFH45797.1 - 3.3e-06 25.5 0.3 0.0049 15.0 0.0 3.1 3 0 0 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.6 KFH45797.1 - 0.0004 20.1 0.2 0.24 11.1 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A DUF1513 PF07433.6 KFH45797.1 - 0.0032 16.4 0.0 0.16 10.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1513) PQQ_2 PF13360.1 KFH45797.1 - 0.0085 15.5 0.2 0.075 12.4 0.1 2.4 1 1 2 3 3 3 1 PQQ-like domain Coatomer_WDAD PF04053.9 KFH45797.1 - 0.01 14.6 0.0 0.02 13.7 0.0 1.5 1 0 0 1 1 1 0 Coatomer WD associated region Apc4_WD40 PF12894.2 KFH45797.1 - 0.04 13.4 0.0 0.64 9.5 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.11 KFH45797.1 - 0.072 11.3 0.0 1.4 7.1 0.0 2.1 1 1 1 2 2 2 0 Cytochrome D1 heme domain DUF2406 PF10295.4 KFH45800.1 - 9.7e-21 74.0 0.3 9.7e-21 74.0 0.2 4.1 4 1 0 4 4 4 1 Uncharacterised protein (DUF2406) Gal_mutarotas_2 PF13802.1 KFH45800.1 - 0.062 13.1 0.6 0.14 12.0 0.1 1.8 2 0 0 2 2 2 0 Galactose mutarotase-like G6PD_C PF02781.11 KFH45801.1 - 1.2e-133 444.4 0.0 1.8e-133 443.9 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 KFH45801.1 - 1.7e-50 171.8 0.1 1.6e-29 103.4 0.0 2.4 2 0 0 2 2 2 2 Glucose-6-phosphate dehydrogenase, NAD binding domain IDO PF01231.13 KFH45801.1 - 0.022 13.1 0.1 0.031 12.7 0.0 1.1 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase GST_N_3 PF13417.1 KFH45802.1 - 1.6e-19 69.9 0.0 3.1e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFH45802.1 - 2.2e-12 46.7 0.0 4.1e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFH45802.1 - 7.7e-05 22.5 1.4 0.00015 21.5 0.2 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFH45802.1 - 0.02 14.8 0.2 0.12 12.3 0.0 2.4 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain DUF759 PF05537.6 KFH45803.1 - 0.0015 17.4 0.3 0.0022 16.8 0.2 1.2 1 0 0 1 1 1 1 Borrelia burgdorferi protein of unknown function (DUF759) DUF4646 PF15496.1 KFH45803.1 - 0.016 15.2 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) Sel1 PF08238.7 KFH45804.1 - 3.7e-37 125.9 30.8 2.7e-06 27.7 0.0 7.5 7 0 0 7 7 7 7 Sel1 repeat Noggin PF05806.7 KFH45804.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Noggin Amino_oxidase PF01593.19 KFH45805.1 - 4.4e-13 49.1 0.1 9e-13 48.0 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KFH45805.1 - 1.2e-09 38.0 0.1 3.6e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFH45805.1 - 5.5e-08 32.1 0.2 2.2e-06 26.8 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFH45805.1 - 0.0036 17.1 0.0 0.023 14.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFH45805.1 - 0.02 13.9 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 KFH45805.1 - 0.048 14.0 0.1 1.9 8.9 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFH45805.1 - 0.11 12.5 0.1 0.25 11.3 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFH45805.1 - 0.15 11.8 0.3 0.52 10.0 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding HLH PF00010.21 KFH45806.1 - 2.8e-11 42.9 0.0 6.9e-11 41.6 0.0 1.7 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain p450 PF00067.17 KFH45807.1 - 2e-65 221.1 0.0 2.9e-65 220.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TUG-UBL1 PF11470.3 KFH45808.1 - 5.2e-24 83.9 0.0 1.1e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 GLUT4 regulating protein TUG DUF4294 PF14127.1 KFH45808.1 - 0.022 14.3 0.2 0.041 13.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4294) RBD PF02196.10 KFH45808.1 - 0.031 14.0 0.2 0.18 11.6 0.1 2.0 2 0 0 2 2 2 0 Raf-like Ras-binding domain Rad60-SLD PF11976.3 KFH45808.1 - 0.048 13.3 0.1 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like E_Pc_C PF06752.7 KFH45810.1 - 0.096 12.1 1.0 1.2 8.5 0.0 2.1 2 0 0 2 2 2 0 Enhancer of Polycomb C-terminus Got1 PF04178.7 KFH45811.1 - 3.1e-31 107.9 17.7 3.8e-31 107.6 12.3 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Peptidase_M50 PF02163.17 KFH45811.1 - 0.019 13.8 0.3 0.03 13.2 0.2 1.5 1 1 0 1 1 1 0 Peptidase family M50 SUR7 PF06687.7 KFH45811.1 - 2.7 7.4 9.1 6.1 6.3 6.3 1.5 1 1 0 1 1 1 0 SUR7/PalI family Podoplanin PF05808.6 KFH45812.1 - 0.56 9.7 9.1 0.71 9.4 6.3 1.2 1 0 0 1 1 1 0 Podoplanin Syja_N PF02383.13 KFH45813.1 - 2.5e-81 272.9 0.0 4.2e-81 272.1 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 KFH45813.1 - 4.1e-26 92.4 0.0 7.2e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Metallophos PF00149.23 KFH45813.1 - 0.071 12.4 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase SNF2_N PF00176.18 KFH45814.1 - 7.1e-55 185.9 0.0 9.8e-55 185.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFH45814.1 - 1.7e-12 46.9 0.1 6.9e-12 45.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UBA PF00627.26 KFH45814.1 - 1e-05 25.1 0.2 3.2e-05 23.6 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain ResIII PF04851.10 KFH45814.1 - 0.003 17.4 0.0 0.017 14.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UBA_4 PF14555.1 KFH45814.1 - 0.0081 15.6 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain HHH_3 PF12836.2 KFH45814.1 - 0.077 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF3890 PF13029.1 KFH45814.1 - 0.2 11.7 0.4 0.61 10.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3890) bZIP_1 PF00170.16 KFH45815.1 - 0.0086 16.0 11.6 0.02 14.8 8.0 1.6 1 1 0 1 1 1 1 bZIP transcription factor DUF972 PF06156.8 KFH45815.1 - 0.08 13.2 0.6 0.16 12.3 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) HeH PF12949.2 KFH45815.1 - 0.15 11.6 0.0 0.86 9.2 0.0 2.2 3 0 0 3 3 3 0 HeH/LEM domain PAP1 PF08601.5 KFH45815.1 - 0.47 10.0 6.2 2.1 7.9 0.0 2.9 3 0 0 3 3 3 0 Transcription factor PAP1 DUF904 PF06005.7 KFH45815.1 - 2 8.7 7.8 0.26 11.5 1.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF904) NYD-SP28_assoc PF14775.1 KFH45815.1 - 3 7.6 7.3 12 5.6 5.1 2.0 1 1 0 1 1 1 0 Sperm tail C-terminal domain bZIP_2 PF07716.10 KFH45815.1 - 3.8 7.3 14.3 26 4.7 9.9 2.2 1 1 0 1 1 1 0 Basic region leucine zipper 7TMR-DISM_7TM PF07695.6 KFH45816.1 - 1.5 8.4 8.8 2.7 7.6 6.1 1.5 1 1 0 1 1 1 0 7TM diverse intracellular signalling Pyr_redox_3 PF13738.1 KFH45817.1 - 2.8e-22 79.7 0.0 8.6e-22 78.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFH45817.1 - 1.6e-13 50.3 0.0 1.1e-09 37.6 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 KFH45817.1 - 3.8e-13 48.4 0.0 4.2e-09 35.1 0.0 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KFH45817.1 - 8.9e-09 35.5 0.0 2.2e-08 34.2 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFH45817.1 - 3.2e-06 27.0 0.0 1.4e-05 25.0 0.0 2.2 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KFH45817.1 - 5.9e-06 25.5 0.2 0.00015 20.9 0.7 2.1 1 1 1 2 2 2 1 FAD binding domain DAO PF01266.19 KFH45817.1 - 6e-06 25.4 2.1 0.0011 17.9 0.1 2.8 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFH45817.1 - 2.4e-05 24.6 0.7 0.017 15.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KFH45817.1 - 0.00012 22.1 0.0 0.15 12.1 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 KFH45817.1 - 0.00063 19.5 0.3 0.15 11.8 0.0 3.2 2 1 1 3 3 3 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 KFH45817.1 - 0.00077 18.6 0.1 0.009 15.1 0.0 2.3 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 KFH45817.1 - 0.0011 17.9 4.4 0.0016 17.4 0.5 2.6 2 1 1 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.7 KFH45817.1 - 0.0021 17.0 0.0 0.005 15.8 0.0 1.6 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_10 PF13460.1 KFH45817.1 - 0.0028 17.6 0.0 0.073 13.0 0.0 2.3 2 0 0 2 2 2 1 NADH(P)-binding HI0933_like PF03486.9 KFH45817.1 - 0.0045 15.5 0.3 0.011 14.2 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_7 PF13241.1 KFH45817.1 - 0.0049 17.0 0.0 1.4 9.1 0.0 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding Amino_oxidase PF01593.19 KFH45817.1 - 0.0088 15.1 0.1 0.02 13.9 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase F420_oxidored PF03807.12 KFH45817.1 - 0.012 16.0 0.0 2.2 8.7 0.0 3.4 4 0 0 4 4 3 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 KFH45817.1 - 0.015 15.3 0.0 0.043 13.8 0.0 1.8 2 0 0 2 2 1 0 TrkA-N domain GIDA PF01134.17 KFH45817.1 - 0.017 13.9 0.1 0.21 10.4 0.1 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A CPSase_L_chain PF00289.17 KFH45817.1 - 0.017 15.1 0.0 0.74 9.9 0.0 2.2 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Thi4 PF01946.12 KFH45817.1 - 0.031 13.3 0.0 0.085 11.9 0.0 1.7 1 0 0 1 1 1 0 Thi4 family ThiF PF00899.16 KFH45817.1 - 0.032 14.0 0.6 2.9 7.7 0.0 2.4 2 0 0 2 2 2 0 ThiF family ApbA PF02558.11 KFH45817.1 - 0.058 12.8 0.2 0.5 9.7 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA ELFV_dehydrog PF00208.16 KFH45817.1 - 0.082 12.4 0.5 0.34 10.4 0.3 1.8 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.16 KFH45817.1 - 0.14 11.7 0.7 1.7 8.1 0.0 2.5 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Cyclin_N PF00134.18 KFH45819.1 - 8.6e-43 144.9 0.0 2.2e-42 143.6 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFH45819.1 - 2.1e-33 114.7 0.0 4.2e-33 113.7 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Erythro_esteras PF05139.9 KFH45820.1 - 7.5e-134 446.2 0.2 1.1e-133 445.7 0.1 1.3 1 0 0 1 1 1 1 Erythromycin esterase PSP PF04046.11 KFH45820.1 - 0.043 13.2 0.3 0.35 10.2 0.0 2.3 2 0 0 2 2 2 0 PSP Rho_N PF07498.7 KFH45821.1 - 0.021 14.5 0.1 0.036 13.8 0.1 1.4 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain ICL PF00463.16 KFH45822.1 - 1.8e-280 930.5 1.1 2.1e-280 930.4 0.8 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KFH45822.1 - 1.8e-11 43.7 0.1 4.8e-11 42.3 0.0 1.8 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Pkinase PF00069.20 KFH45823.1 - 2.2e-59 200.7 0.0 2.8e-59 200.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH45823.1 - 1.8e-38 132.1 0.0 2.3e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH45823.1 - 5.6e-07 28.8 0.0 9.3e-07 28.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like CDC45 PF02724.9 KFH45824.1 - 0.15 10.0 7.1 0.2 9.6 4.9 1.1 1 0 0 1 1 1 0 CDC45-like protein GEMIN8 PF15348.1 KFH45824.1 - 0.15 12.0 3.3 0.32 11.0 2.3 1.5 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Sec3_C PF09763.4 KFH45824.1 - 0.26 9.3 4.2 0.29 9.1 2.9 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 Senescence_reg PF04520.8 KFH45824.1 - 1.3 9.5 10.8 0.31 11.5 5.0 1.8 2 0 0 2 2 2 0 Senescence regulator Pex14_N PF04695.8 KFH45824.1 - 3.7 7.5 11.5 6.9 6.7 5.0 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Polyoma_lg_T_C PF06431.6 KFH45824.1 - 7.4 5.1 6.3 13 4.3 4.4 1.3 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus FUSC_2 PF13515.1 KFH45825.1 - 1.5e-22 79.8 8.7 1.5e-22 79.8 6.1 2.7 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.7 KFH45825.1 - 2.8e-12 45.9 3.3 8e-10 37.7 0.6 2.5 2 0 0 2 2 2 2 Fusaric acid resistance protein family ALMT PF11744.3 KFH45825.1 - 2e-05 23.4 11.8 0.0068 15.1 5.9 3.6 3 1 0 3 3 3 2 Aluminium activated malate transporter DUF2422 PF10337.4 KFH45825.1 - 7.9e-05 21.6 0.1 7.9e-05 21.6 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 KFH45825.1 - 0.02 14.5 0.1 0.11 12.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2421) FUSC-like PF12805.2 KFH45825.1 - 0.05 12.5 7.8 1 8.2 0.1 2.5 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS Amidohydro_2 PF04909.9 KFH45826.1 - 3.5e-20 72.6 0.0 3.5e-19 69.4 0.0 2.3 2 1 0 2 2 2 1 Amidohydrolase Snf7 PF03357.16 KFH45827.1 - 2e-32 111.9 20.0 2e-32 111.9 13.9 2.0 1 1 1 2 2 2 1 Snf7 Rhamno_transf PF11316.3 KFH45827.1 - 0.024 13.8 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative rhamnosyl transferase Allexi_40kDa PF05549.6 KFH45827.1 - 0.58 9.3 6.5 0.99 8.6 4.5 1.6 1 1 0 1 1 1 0 Allexivirus 40kDa protein DUF2937 PF11157.3 KFH45827.1 - 0.66 9.2 6.8 0.24 10.7 2.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) MutS_III PF05192.13 KFH45827.1 - 3.6 7.3 6.8 2.8 7.6 3.8 1.5 1 1 0 1 1 1 0 MutS domain III HK97-gp10_like PF04883.7 KFH45827.1 - 5.6 7.9 5.9 1.1 10.2 0.2 2.5 3 0 0 3 3 3 0 Bacteriophage HK97-gp10, putative tail-component CMD PF02627.15 KFH45828.1 - 4.2e-10 39.3 0.3 5.9e-09 35.6 0.1 2.1 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family KilA-N PF04383.8 KFH45829.1 - 0.00018 21.0 0.0 0.0029 17.2 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain CDC50 PF03381.10 KFH45830.1 - 2.8e-99 331.7 0.0 3.5e-99 331.4 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family 60KD_IMP PF02096.15 KFH45830.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 60Kd inner membrane protein PTCB-BRCT PF12738.2 KFH45832.1 - 4e-05 23.3 0.0 7.8e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 KFH45832.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain RAM PF15320.1 KFH45832.1 - 6.6 7.0 6.9 2.9 8.2 2.3 2.2 2 0 0 2 2 2 0 mRNA cap methylation, RNMT-activating mini protein Pneumo_att_G PF05539.6 KFH45834.1 - 0.2 10.9 8.0 0.18 11.1 5.5 1.2 1 1 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Lipid_DES PF08557.5 KFH45834.1 - 1.2 8.4 3.7 6.3 6.1 0.3 2.5 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) Flocculin_t3 PF13928.1 KFH45835.1 - 0.076 13.1 7.1 0.076 13.1 4.9 2.6 2 1 1 3 3 3 0 Flocculin type 3 repeat CFEM PF05730.6 KFH45836.1 - 0.048 13.4 2.0 0.084 12.7 1.4 1.4 1 0 0 1 1 1 0 CFEM domain Pex24p PF06398.6 KFH45837.1 - 1.4e-96 323.4 0.2 1.7e-96 323.1 0.1 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Reticulon PF02453.12 KFH45837.1 - 0.0097 15.5 0.7 0.029 14.0 0.2 1.9 1 1 1 2 2 2 1 Reticulon Metal_resist PF13801.1 KFH45837.1 - 0.024 14.6 0.5 0.055 13.4 0.0 1.9 2 0 0 2 2 2 0 Heavy-metal resistance DUF3292 PF11696.3 KFH45837.1 - 0.12 10.2 0.3 0.32 8.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) ArsA_ATPase PF02374.10 KFH45838.1 - 2.7e-108 361.6 0.0 3.3e-108 361.3 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 KFH45838.1 - 2.1e-15 56.6 0.1 4.2e-15 55.6 0.1 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KFH45838.1 - 7.5e-10 38.9 0.0 8.5e-09 35.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 KFH45838.1 - 5.3e-06 25.8 0.0 1.1e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 KFH45838.1 - 0.00016 21.1 0.0 0.0021 17.5 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_10 PF12846.2 KFH45838.1 - 0.0024 17.3 0.0 0.0031 17.0 0.0 1.1 1 0 0 1 1 1 1 AAA-like domain AAA_19 PF13245.1 KFH45838.1 - 0.0041 16.8 0.0 0.013 15.1 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 KFH45838.1 - 0.0085 15.5 0.1 0.021 14.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain YhjQ PF06564.7 KFH45838.1 - 0.01 15.2 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 YhjQ protein IstB_IS21 PF01695.12 KFH45838.1 - 0.017 14.5 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein MipZ PF09140.6 KFH45838.1 - 0.028 13.4 0.0 0.051 12.6 0.0 1.4 1 0 0 1 1 1 0 ATPase MipZ AAA_18 PF13238.1 KFH45838.1 - 0.035 14.4 0.0 0.075 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KFH45838.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Rep_fac-A_C PF08646.5 KFH45839.1 - 3e-52 176.2 0.9 4e-51 172.5 0.4 2.3 2 0 0 2 2 2 1 Replication factor-A C terminal domain Rep-A_N PF04057.7 KFH45839.1 - 1.8e-21 75.7 0.0 3.5e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 KFH45839.1 - 2.1e-14 53.1 0.2 3.5e-10 39.6 0.0 3.2 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain zf-like PF04071.7 KFH45839.1 - 0.01 15.5 0.2 0.029 14.0 0.1 1.8 1 0 0 1 1 1 0 Cysteine-rich small domain Chitin_synth_1N PF08407.6 KFH45839.1 - 0.092 12.4 0.5 0.26 11.0 0.1 1.9 2 0 0 2 2 2 0 Chitin synthase N-terminal ADH_zinc_N PF00107.21 KFH45840.1 - 7.1e-26 90.2 0.0 1.4e-25 89.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFH45840.1 - 4.5e-22 79.2 0.0 9e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFH45840.1 - 3e-10 39.8 0.0 8e-09 35.2 0.0 2.3 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain SH2_2 PF14633.1 KFH45841.1 - 8.8e-78 260.3 0.0 2.5e-77 258.9 0.0 1.8 1 0 0 1 1 1 1 SH2 domain DLD PF14878.1 KFH45841.1 - 2.1e-35 121.2 3.2 2.1e-35 121.2 2.2 4.7 4 0 0 4 4 4 1 Death-like domain of SPT6 YqgF PF14639.1 KFH45841.1 - 6.1e-30 103.7 0.0 2.2e-29 101.9 0.0 2.1 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.1 KFH45841.1 - 4.8e-29 100.5 0.0 1e-28 99.4 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.1 KFH45841.1 - 3e-22 78.8 0.5 1.6e-21 76.5 0.4 2.3 1 1 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.1 KFH45841.1 - 4.3e-22 78.0 32.1 4.3e-22 78.0 22.2 5.9 5 1 1 6 6 6 1 Acidic N-terminal SPT6 SH2 PF00017.19 KFH45841.1 - 0.0003 20.5 0.0 0.00071 19.3 0.0 1.7 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.2 KFH45841.1 - 0.023 14.6 0.0 0.095 12.6 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif Peptidase_M20 PF01546.23 KFH45842.1 - 1e-32 113.1 0.1 1.7e-32 112.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KFH45842.1 - 6.9e-13 48.3 0.0 1.1e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF761 PF05553.6 KFH45842.1 - 0.15 11.4 0.1 0.38 10.1 0.0 1.6 1 0 0 1 1 1 0 Cotton fibre expressed protein zf-U1 PF06220.7 KFH45843.1 - 1.1e-17 63.2 3.1 1.8e-17 62.5 2.1 1.3 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 KFH45843.1 - 0.098 12.8 2.3 0.25 11.5 1.6 1.6 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding APH PF01636.18 KFH45844.1 - 2.5e-08 33.9 2.4 6.8e-06 25.9 0.7 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 KFH45844.1 - 2.6e-07 30.0 0.0 3.9e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KFH45844.1 - 1.1e-06 27.9 0.0 0.0011 18.0 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFH45844.1 - 0.00015 21.1 0.0 0.00026 20.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.12 KFH45844.1 - 0.035 13.1 0.0 0.053 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Peptidase_S10 PF00450.17 KFH45845.1 - 4e-114 382.0 0.0 5.1e-114 381.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KFH45845.1 - 0.00012 22.0 0.0 0.00033 20.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Act-Frag_cataly PF09192.5 KFH45845.1 - 0.057 12.3 0.0 0.093 11.6 0.0 1.2 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic Rifin_STEVOR PF02009.11 KFH45845.1 - 0.23 11.0 0.0 0.38 10.3 0.0 1.3 1 0 0 1 1 1 0 Rifin/stevor family DUF3708 PF12501.3 KFH45845.1 - 1.2 8.9 3.0 0.77 9.5 0.1 1.9 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter Chitin_synth_1 PF01644.12 KFH45846.1 - 4.6e-69 231.3 0.0 6.8e-69 230.8 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 KFH45846.1 - 1.6e-28 99.4 0.0 2.4e-23 82.3 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 KFH45846.1 - 1.9e-26 91.5 0.0 3.6e-26 90.6 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 KFH45846.1 - 1e-11 44.9 0.1 3.2e-11 43.2 0.1 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KFH45846.1 - 6.1e-10 39.2 0.0 4.6e-09 36.4 0.0 2.3 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Spc97_Spc98 PF04130.8 KFH45847.1 - 2.8e-120 402.2 0.0 3.3e-120 401.9 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family UQ_con PF00179.21 KFH45848.1 - 1.2e-34 118.7 0.0 1.8e-34 118.1 0.0 1.2 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Tantalus PF15386.1 KFH45848.1 - 0.049 13.3 0.0 0.099 12.4 0.0 1.5 1 0 0 1 1 1 0 Drosophila Tantalus-like Prok-E2_B PF14461.1 KFH45848.1 - 0.096 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Lipase_GDSL_2 PF13472.1 KFH45849.1 - 5.8e-20 72.1 0.0 7e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFH45849.1 - 2.6e-17 63.4 0.0 3.1e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 KFH45849.1 - 0.00093 18.9 0.1 0.0035 17.1 0.1 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family WWbp PF10349.4 KFH45850.1 - 0.48 11.3 13.3 0.57 11.0 9.2 1.2 1 0 0 1 1 1 0 WW-domain ligand protein Yippee-Mis18 PF03226.9 KFH45852.1 - 1.4e-19 69.8 0.0 2e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 KFH45852.1 - 0.0014 18.5 0.1 0.028 14.2 0.0 2.0 2 0 0 2 2 2 1 C-terminal domain of RIG-I PALP PF00291.20 KFH45853.1 - 6.8e-64 216.0 1.6 9.7e-64 215.5 1.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KFH45853.1 - 0.069 12.1 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family SAICAR_synt PF01259.13 KFH45854.1 - 6.4e-77 258.0 0.0 7.6e-77 257.7 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Aldo_ket_red PF00248.16 KFH45855.1 - 1.5e-09 37.0 0.0 2.2e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 KFH45856.1 - 2.3e-44 151.5 30.0 2.3e-44 151.5 20.8 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH45856.1 - 3.7e-09 35.6 10.3 3.7e-09 35.6 7.1 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter DUF3405 PF11885.3 KFH45857.1 - 4.8e-179 595.7 0.5 9.5e-179 594.7 0.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) Sdh5 PF03937.11 KFH45858.1 - 7.1e-24 83.2 0.0 1.4e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase cNMP_binding PF00027.24 KFH45859.1 - 3.3e-40 135.7 0.0 1.7e-20 72.5 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase PF00069.20 KFH45860.1 - 6e-76 255.0 0.0 9.7e-76 254.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH45860.1 - 1.1e-37 129.4 0.0 1.9e-37 128.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 KFH45860.1 - 2.9e-15 56.1 0.2 6.4e-15 55.0 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 KFH45860.1 - 4.7e-07 29.0 0.0 1.6e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 KFH45860.1 - 0.00028 20.2 0.1 0.00057 19.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 KFH45860.1 - 0.0029 16.2 0.3 0.0058 15.2 0.0 1.5 2 0 0 2 2 2 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.18 KFH45860.1 - 0.063 13.0 0.2 0.32 10.6 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF3439 PF11921.3 KFH45860.1 - 0.53 10.0 15.3 0.5 10.1 9.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 KFH45860.1 - 7.4 4.4 19.4 12 3.6 13.4 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Opy2 PF09463.5 KFH45861.1 - 0.00034 20.6 18.4 0.00054 19.9 12.8 1.3 1 0 0 1 1 1 1 Opy2 protein Syndecan PF01034.15 KFH45861.1 - 0.18 11.4 0.2 0.35 10.5 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain P12 PF12669.2 KFH45861.1 - 0.24 11.6 0.0 0.24 11.6 0.0 2.6 2 1 0 2 2 2 0 Virus attachment protein p12 family Trehalase PF01204.13 KFH45862.1 - 8.6e-187 621.8 0.0 1e-186 621.5 0.0 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 KFH45862.1 - 2.3e-16 58.7 0.6 3.7e-16 58.1 0.4 1.3 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain HAD_2 PF13419.1 KFH45863.1 - 3.6e-15 56.6 0.0 2e-13 50.9 0.0 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFH45863.1 - 1.5e-10 41.8 0.0 5.7e-06 26.9 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFH45863.1 - 1.1e-08 34.6 0.1 2.4e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 KFH45863.1 - 1.6e-05 25.1 0.0 2.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 KFH45863.1 - 0.016 14.6 0.0 1.3 8.3 0.0 2.6 3 1 0 3 3 3 0 Mitochondrial PGP phosphatase Acid_PPase PF12689.2 KFH45863.1 - 0.076 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Acid Phosphatase HD PF01966.17 KFH45864.1 - 2e-05 24.5 1.0 4.4e-05 23.4 0.2 1.9 2 0 0 2 2 2 1 HD domain DNA_pol_E_B PF04042.11 KFH45865.1 - 4.5e-62 209.0 0.0 6.6e-62 208.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Kinetocho_Slk19 PF12709.2 KFH45867.1 - 1e-22 80.0 3.3 1e-22 80.0 2.3 4.7 4 1 0 5 5 5 2 Central kinetochore-associated DUF1180 PF06679.7 KFH45867.1 - 0.027 14.3 5.8 0.024 14.5 1.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) bZIP_1 PF00170.16 KFH45867.1 - 0.03 14.2 0.5 0.03 14.2 0.3 4.8 4 0 0 4 4 4 0 bZIP transcription factor Shugoshin_N PF07558.6 KFH45867.1 - 0.065 12.9 1.2 0.1 12.3 0.1 2.0 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF2605 PF10792.4 KFH45867.1 - 0.069 12.8 1.4 0.15 11.7 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) TMF_DNA_bd PF12329.3 KFH45867.1 - 0.095 12.5 39.5 0.52 10.1 1.0 4.7 3 2 1 4 4 4 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.5 KFH45867.1 - 0.12 12.4 11.9 3.6 7.7 3.7 3.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.6 KFH45867.1 - 0.24 11.3 21.8 0.077 12.9 0.7 5.4 6 0 0 6 6 6 0 Flagella accessory protein C (FlaC) DUF745 PF05335.8 KFH45867.1 - 4.7 6.6 28.9 0.039 13.4 9.4 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF745) DUF2570 PF10828.3 KFH45867.1 - 5.5 6.6 12.0 1.3 8.6 0.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) DUF2205 PF10224.4 KFH45867.1 - 6 6.5 16.9 0.14 11.7 0.3 3.5 3 1 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) SPT16 PF08644.6 KFH45868.1 - 4.9e-56 188.8 0.2 4.9e-56 188.8 0.1 2.7 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 KFH45868.1 - 1e-51 174.7 0.2 1e-51 174.7 0.2 2.0 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Rtt106 PF08512.7 KFH45868.1 - 1.2e-22 79.7 0.1 3.6e-22 78.1 0.1 1.9 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Peptidase_M24 PF00557.19 KFH45868.1 - 1.1e-20 74.1 0.0 2.2e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP-binding PF00501.23 KFH45870.1 - 3.7e-79 266.0 0.0 4.4e-79 265.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFH45870.1 - 3.1e-15 56.8 0.0 6.9e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Transthyretin PF00576.16 KFH45871.1 - 2.8e-25 88.3 0.5 1.1e-14 54.2 0.3 2.1 1 1 1 2 2 2 2 HIUase/Transthyretin family Aft1_HRA PF11786.3 KFH45872.1 - 1.6e-28 98.7 9.5 1.6e-28 98.7 6.6 3.2 3 0 0 3 3 3 1 Aft1 HRA domain Aft1_HRR PF11787.3 KFH45872.1 - 2.1e-13 51.0 32.2 1.7e-10 41.8 1.3 5.8 5 2 1 6 6 6 2 Aft1 HRR domain bZIP_1 PF00170.16 KFH45872.1 - 5.1e-13 48.7 6.3 1.1e-12 47.7 4.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor Aft1_OSA PF11785.3 KFH45872.1 - 1.3e-08 35.1 33.0 1.3e-08 35.1 22.9 5.8 4 2 0 4 4 4 1 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.10 KFH45872.1 - 1.3e-05 24.9 6.2 1.3e-05 24.9 4.3 3.1 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFH45872.1 - 0.0022 18.2 3.0 0.0022 18.2 2.1 3.3 3 0 0 3 3 3 1 bZIP Maf transcription factor Spt20 PF12090.3 KFH45872.1 - 2.7 7.3 25.1 4.1 6.7 5.9 2.5 2 0 0 2 2 2 0 Spt20 family Dala_Dala_lig_N PF01820.16 KFH45872.1 - 8 6.8 10.9 1.2 9.4 0.3 3.1 3 0 0 3 3 3 0 D-ala D-ala ligase N-terminus FimP PF09766.4 KFH45872.1 - 9.4 5.1 38.1 0.22 10.5 6.8 3.2 3 0 0 3 3 3 0 Fms-interacting protein HABP4_PAI-RBP1 PF04774.10 KFH45873.1 - 0.00013 22.3 0.2 0.00023 21.6 0.1 1.4 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family RNA_Me_trans PF04252.8 KFH45874.1 - 2.6e-46 157.4 0.0 3e-46 157.3 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase DWNN PF08783.6 KFH45875.1 - 6.5e-30 102.9 0.1 1.2e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 KFH45875.1 - 2.9e-05 23.4 3.0 8e-05 22.0 2.1 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 KFH45875.1 - 0.00035 20.3 2.0 0.00081 19.2 1.4 1.6 1 0 0 1 1 1 1 Zinc knuckle U-box PF04564.10 KFH45875.1 - 0.0009 19.1 0.1 0.0029 17.5 0.0 1.9 2 0 0 2 2 1 1 U-box domain zf-CCHC_3 PF13917.1 KFH45875.1 - 0.0077 15.9 0.4 0.027 14.1 0.3 2.0 1 0 0 1 1 1 1 Zinc knuckle zf-RING_6 PF14835.1 KFH45875.1 - 0.02 14.6 1.3 0.037 13.8 0.9 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 KFH45875.1 - 0.043 13.3 5.5 0.096 12.2 3.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FYVE_2 PF02318.11 KFH45875.1 - 0.18 11.7 4.5 0.063 13.1 1.1 1.7 2 0 0 2 2 1 0 FYVE-type zinc finger zf-Nse PF11789.3 KFH45875.1 - 0.25 10.8 6.3 0.46 10.0 3.4 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.20 KFH45875.1 - 0.34 10.6 8.6 0.73 9.5 6.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFH45875.1 - 0.36 10.9 13.7 0.039 13.9 5.5 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFH45875.1 - 0.4 10.4 13.6 0.033 13.9 5.3 2.0 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFH45875.1 - 1.9 8.4 8.1 6 6.8 5.6 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KFH45875.1 - 2.1 8.2 12.3 0.072 12.9 4.3 1.7 2 0 0 2 2 2 0 Ring finger domain DLH PF01738.13 KFH45877.1 - 4.7e-20 71.8 0.1 1.8e-18 66.6 0.1 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KFH45877.1 - 1.4e-07 31.3 0.0 2.1e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Pkinase PF00069.20 KFH45878.1 - 5.6e-56 189.5 0.0 5.6e-56 189.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH45878.1 - 1.4e-20 73.5 0.0 3.6e-20 72.1 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFH45878.1 - 0.024 14.3 0.0 0.024 14.3 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family BAF1_ABF1 PF04684.8 KFH45878.1 - 0.18 10.6 13.4 0.33 9.7 9.3 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor FimP PF09766.4 KFH45878.1 - 0.79 8.7 14.0 1.5 7.7 9.7 1.4 1 0 0 1 1 1 0 Fms-interacting protein MFS_1 PF07690.11 KFH45879.1 - 9.7e-47 159.3 40.9 3.5e-42 144.3 17.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Aldedh PF00171.17 KFH45880.1 - 2.7e-16 58.9 11.9 5.2e-10 38.2 6.7 2.7 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Mito_fiss_reg PF05308.6 KFH45881.1 - 2.5 7.3 5.5 2.7 7.3 3.8 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator zf-CCHC PF00098.18 KFH45882.1 - 1.5e-43 144.6 99.8 6.8e-07 28.9 0.7 12.2 12 0 0 12 12 12 11 Zinc knuckle zf-CCHC_4 PF14392.1 KFH45882.1 - 0.0028 17.3 81.6 0.14 11.8 1.4 10.7 11 1 1 12 12 12 8 Zinc knuckle zf-CCHC_2 PF13696.1 KFH45882.1 - 0.0087 15.5 1.2 0.0087 15.5 0.8 9.0 7 3 4 11 11 11 5 Zinc knuckle zf-CCHC_3 PF13917.1 KFH45882.1 - 0.022 14.4 2.7 0.022 14.4 1.9 10.6 5 3 6 11 11 11 0 Zinc knuckle IlvN PF07991.7 KFH45884.1 - 4.9e-46 156.1 0.0 6.9e-46 155.6 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 KFH45884.1 - 2.8e-44 150.5 0.0 4e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 KFH45884.1 - 0.02 15.2 0.1 0.065 13.6 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent MIS13 PF08202.6 KFH45885.1 - 1.4e-58 198.3 0.0 2.2e-58 197.7 0.0 1.3 1 0 0 1 1 1 1 Mis12-Mtw1 protein family Tektin PF03148.9 KFH45885.1 - 0.37 9.2 7.3 0.053 12.0 1.2 1.9 2 0 0 2 2 2 0 Tektin family DivIC PF04977.10 KFH45885.1 - 0.59 9.6 2.9 4.8 6.7 0.2 2.4 2 0 0 2 2 2 0 Septum formation initiator BCAS2 PF05700.6 KFH45886.1 - 1.3e-45 155.6 0.2 1.5e-45 155.4 0.1 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) TMF_TATA_bd PF12325.3 KFH45886.1 - 0.00074 19.2 3.5 0.0013 18.4 2.4 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding EMP24_GP25L PF01105.19 KFH45887.1 - 3.6e-41 140.9 0.0 4.3e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SAGA-Tad1 PF12767.2 KFH45888.1 - 7.1e-46 156.9 0.0 9.4e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TTL PF03133.10 KFH45890.1 - 1.8e-56 191.2 0.0 2.6e-56 190.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 KFH45890.1 - 1.8e-45 154.6 0.0 2.9e-45 154.0 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.1 KFH45890.1 - 5e-05 22.2 0.0 0.0002 20.2 0.0 1.8 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 KFH45890.1 - 8e-05 22.4 0.0 0.016 14.9 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KFH45890.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ThiF PF00899.16 KFH45891.1 - 6.3e-34 116.7 0.0 1.2e-33 115.8 0.0 1.4 1 0 0 1 1 1 1 ThiF family Glyco_hydro_17 PF00332.13 KFH45891.1 - 0.0012 18.0 0.0 0.0017 17.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 TrkA_N PF02254.13 KFH45891.1 - 0.0052 16.7 1.7 0.033 14.2 0.1 2.8 3 0 0 3 3 3 1 TrkA-N domain NAD_binding_7 PF13241.1 KFH45891.1 - 0.0057 16.8 0.0 0.022 15.0 0.0 1.9 2 0 0 2 2 2 1 Putative NAD(P)-binding ApbA PF02558.11 KFH45891.1 - 0.011 15.1 0.1 0.021 14.2 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DAO PF01266.19 KFH45891.1 - 0.012 14.5 0.1 0.025 13.4 0.1 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase AA_kinase PF00696.23 KFH45891.1 - 0.03 13.8 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 Amino acid kinase family Ldh_1_N PF00056.18 KFH45891.1 - 0.035 13.9 0.1 0.076 12.8 0.1 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KFH45891.1 - 0.043 13.1 0.2 0.078 12.3 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 KFH45891.1 - 0.046 13.3 0.1 0.099 12.2 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Coatomer_E PF04733.9 KFH45891.1 - 0.094 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Coatomer epsilon subunit Pyr_redox PF00070.22 KFH45891.1 - 0.11 12.9 0.2 0.33 11.3 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Saccharop_dh PF03435.13 KFH45891.1 - 0.15 10.9 0.2 0.55 9.1 0.2 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase Acyl-CoA_dh_2 PF08028.6 KFH45892.1 - 1.8e-18 67.0 0.3 1.8e-18 67.0 0.2 1.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFH45892.1 - 1.8e-06 28.5 0.0 3.2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 KFH45892.1 - 0.00043 20.4 1.6 0.0017 18.4 0.1 2.5 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DUF2190 PF09956.4 KFH45892.1 - 0.018 14.7 0.4 0.057 13.2 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2190) Gly_transf_sug PF04488.10 KFH45893.1 - 1.6e-13 50.8 0.0 4.7e-13 49.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif ETRAMP PF09716.5 KFH45893.1 - 0.17 11.8 0.1 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Methyltransf_23 PF13489.1 KFH45894.1 - 1.8e-12 47.2 0.0 3.7e-12 46.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH45894.1 - 5.8e-06 26.8 0.0 0.0001 22.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH45894.1 - 1.8e-05 25.1 0.0 3.4e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFH45894.1 - 1.9e-05 24.6 0.0 5.1e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH45894.1 - 3.1e-05 24.3 0.0 0.00011 22.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH45894.1 - 0.00078 19.0 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFH45894.1 - 0.022 13.8 0.0 0.032 13.3 0.0 1.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.12 KFH45894.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_8 PF05148.10 KFH45894.1 - 0.15 11.6 0.0 0.35 10.4 0.0 1.5 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_25 PF13649.1 KFH45894.1 - 0.16 12.3 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain AMP-binding PF00501.23 KFH45895.1 - 7.2e-80 268.4 0.2 9.2e-80 268.0 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFH45895.1 - 9.6e-10 39.2 0.9 2.5e-09 37.9 0.6 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TRAM_LAG1_CLN8 PF03798.11 KFH45896.1 - 9.1e-43 146.1 17.4 1.5e-42 145.3 12.1 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 KFH45896.1 - 1.6e-18 65.9 0.2 3.7e-18 64.7 0.2 1.7 1 0 0 1 1 1 1 TRAM1-like protein SIR2 PF02146.12 KFH45897.1 - 4.9e-57 192.5 0.0 7.7e-57 191.8 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 KFH45897.1 - 0.00037 20.0 0.0 0.0007 19.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 KFH45897.1 - 0.002 17.9 0.1 1.6 8.5 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain S4 PF01479.20 KFH45898.1 - 1.5e-12 46.7 0.0 4.2e-12 45.3 0.0 1.7 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.14 KFH45898.1 - 2.4e-12 47.0 0.7 3.8e-12 46.4 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain GHMP_kinases_N PF00288.21 KFH45899.1 - 5.7e-12 45.5 0.1 1.2e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KFH45899.1 - 3e-06 27.3 0.8 9.2e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases C terminal Kelch_3 PF13415.1 KFH45900.1 - 1.3e-28 98.4 19.7 3.2e-10 39.8 0.2 8.8 8 2 0 8 8 8 5 Galactose oxidase, central domain Kelch_4 PF13418.1 KFH45900.1 - 1.1e-23 82.7 20.5 2.8e-08 33.4 0.1 8.0 9 1 0 9 9 9 5 Galactose oxidase, central domain Kelch_6 PF13964.1 KFH45900.1 - 7.8e-20 70.1 1.6 1e-07 31.8 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 KFH45900.1 - 1.3e-16 59.8 3.8 5.3e-07 29.0 0.0 5.6 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.1 KFH45900.1 - 2.2e-16 59.4 7.0 9.5e-05 22.2 0.0 6.8 7 1 0 7 7 7 3 Kelch motif Kelch_2 PF07646.10 KFH45900.1 - 3.6e-16 58.1 1.6 1.4e-07 31.0 0.0 5.4 5 0 0 5 5 5 3 Kelch motif FAD_binding_4 PF01565.18 KFH45901.1 - 2.4e-13 49.7 0.0 3.8e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DUF4263 PF14082.1 KFH45901.1 - 0.042 13.8 0.0 0.15 11.9 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4263) Septin PF00735.13 KFH45902.1 - 8.6e-103 343.2 0.1 1.6e-102 342.3 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KFH45902.1 - 0.0004 20.3 0.0 0.0008 19.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KFH45902.1 - 0.0017 17.5 0.2 0.0054 15.9 0.2 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KFH45902.1 - 0.011 15.5 5.3 1.4 8.6 0.0 3.0 2 1 1 3 3 3 0 Dynamin family GTP_EFTU PF00009.22 KFH45902.1 - 0.023 14.1 0.1 0.064 12.6 0.0 1.7 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 KFH45902.1 - 0.029 14.2 0.0 0.068 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KFH45902.1 - 0.036 13.5 0.0 0.087 12.2 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family Miro PF08477.8 KFH45902.1 - 0.049 14.1 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_17 PF13207.1 KFH45902.1 - 0.058 14.2 4.2 0.19 12.5 0.1 3.0 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.1 KFH45902.1 - 0.065 13.3 0.0 0.23 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain IIGP PF05049.8 KFH45902.1 - 0.087 11.6 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.1 KFH45902.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain FMN_bind PF04205.9 KFH45902.1 - 0.16 12.1 0.3 0.84 9.8 0.0 2.3 3 0 0 3 3 3 0 FMN-binding domain PPR_3 PF13812.1 KFH45903.1 - 3.3e-12 45.6 1.1 0.023 14.9 0.0 7.7 8 0 0 8 8 8 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 KFH45903.1 - 1.5e-10 40.8 0.0 0.75 9.8 0.0 6.2 6 0 0 6 6 6 3 PPR repeat family PPR PF01535.15 KFH45903.1 - 7.7e-09 34.9 0.1 2 8.5 0.0 5.8 5 0 0 5 5 5 4 PPR repeat PPR_1 PF12854.2 KFH45903.1 - 0.067 12.6 0.0 12 5.5 0.0 3.2 3 0 0 3 3 3 0 PPR repeat RRM_1 PF00076.17 KFH45905.1 - 6e-16 57.8 0.1 6.1e-15 54.6 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH45905.1 - 7e-10 38.7 0.0 1.4e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH45905.1 - 9.7e-06 25.3 0.0 2e-05 24.3 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EamA PF00892.15 KFH45906.1 - 5.2e-11 42.6 31.2 1e-06 28.7 0.3 3.0 3 2 1 4 4 4 2 EamA-like transporter family EmrE PF13536.1 KFH45906.1 - 1.7e-05 24.9 0.9 1.7e-05 24.9 0.7 2.9 3 1 0 3 3 3 1 Multidrug resistance efflux transporter DUF1673 PF07895.6 KFH45906.1 - 0.024 14.1 5.7 0.049 13.1 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) TPT PF03151.11 KFH45906.1 - 0.053 13.1 22.4 0.072 12.7 7.3 3.6 3 1 0 3 3 3 0 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 KFH45906.1 - 0.18 10.8 3.2 0.19 10.8 0.0 2.1 2 0 0 2 2 2 0 Nucleotide-sugar transporter Peptidase_A24 PF01478.13 KFH45906.1 - 3.5 7.8 16.9 0.1 12.7 4.6 2.9 3 1 0 3 3 3 0 Type IV leader peptidase family Alpha-amylase PF00128.19 KFH45907.1 - 4.9e-96 321.8 0.0 7.9e-96 321.1 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 KFH45907.1 - 0.0098 14.8 0.1 0.021 13.7 0.0 1.5 2 0 0 2 2 2 1 glucanotransferase domain of human glycogen debranching enzyme TPR_12 PF13424.1 KFH45908.1 - 0.0016 18.3 0.1 0.23 11.4 0.0 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFH45908.1 - 0.0038 17.8 0.3 1.3 9.8 0.2 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFH45908.1 - 0.036 14.2 0.1 0.18 12.1 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 KFH45908.1 - 0.041 13.8 1.6 0.43 10.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Thioredox_DsbH PF03190.10 KFH45909.1 - 7.6e-56 188.3 0.0 1.4e-55 187.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 KFH45909.1 - 1.6e-06 27.9 0.0 4.4e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like HTH_10 PF04967.7 KFH45909.1 - 0.058 12.9 0.2 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 HTH DNA binding domain DUF608 PF04685.8 KFH45909.1 - 0.087 11.5 0.1 0.16 10.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF608 Thioredoxin_2 PF13098.1 KFH45909.1 - 0.15 12.2 0.2 0.71 10.0 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain Cerato-platanin PF07249.7 KFH45910.1 - 2.3e-50 169.5 0.9 2.7e-50 169.3 0.6 1.0 1 0 0 1 1 1 1 Cerato-platanin Tubulin PF00091.20 KFH45911.1 - 1.1e-70 237.8 0.0 2.1e-70 236.9 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFH45911.1 - 7.6e-49 164.9 0.1 1.2e-48 164.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KFH45911.1 - 7e-06 26.0 0.0 1.5e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KFH45911.1 - 0.0056 16.1 0.0 0.0093 15.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Pmp3 PF01679.12 KFH45915.1 - 1.4e-26 91.9 5.4 1.5e-26 91.7 3.8 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator MR_MLE_C PF13378.1 KFH45916.1 - 3.4e-34 117.1 0.4 7.9e-34 115.9 0.1 1.7 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 KFH45916.1 - 1.6e-13 50.6 0.1 6.4e-13 48.7 0.1 2.0 1 1 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 KFH45916.1 - 6.3e-10 39.4 0.0 1.6e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Inositol_P PF00459.20 KFH45917.1 - 1.4e-52 178.6 0.8 2.1e-52 178.1 0.6 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family Aminotran_4 PF01063.14 KFH45918.1 - 6.6e-30 104.2 0.0 1e-29 103.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV DUF3210 PF11489.3 KFH45919.1 - 1.4e-181 605.8 89.6 1.4e-181 605.8 62.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3210) Cupin_2 PF07883.6 KFH45920.1 - 0.00011 21.6 1.3 0.19 11.2 0.0 3.6 4 0 0 4 4 4 2 Cupin domain Cupin_6 PF12852.2 KFH45920.1 - 0.0035 16.9 0.4 0.019 14.6 0.0 2.2 3 0 0 3 3 3 1 Cupin AraC_binding PF02311.14 KFH45920.1 - 0.0037 16.9 0.1 4.9 6.8 0.0 2.8 3 0 0 3 3 3 2 AraC-like ligand binding domain PMI_typeI PF01238.16 KFH45920.1 - 0.017 14.1 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Phosphomannose isomerase type I Cupin_3 PF05899.7 KFH45920.1 - 0.031 13.6 0.2 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF861) JmjC PF02373.17 KFH45920.1 - 0.036 14.3 0.0 0.079 13.2 0.0 1.6 1 0 0 1 1 1 0 JmjC domain, hydroxylase MFS_1 PF07690.11 KFH45921.1 - 2e-23 82.6 29.5 2.3e-21 75.9 17.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH45921.1 - 1.3e-05 23.9 22.0 0.0075 14.8 4.2 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter DHDPS PF00701.17 KFH45922.1 - 5.7e-37 126.8 0.0 7e-37 126.5 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family COQ9 PF08511.6 KFH45922.1 - 0.013 15.0 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 COQ9 Toxin_ToxA PF11584.3 KFH45922.1 - 0.092 12.5 0.0 0.77 9.6 0.0 2.1 2 0 0 2 2 2 0 Proteinaceous host-selective toxin ToxA Acetyltransf_7 PF13508.1 KFH45923.1 - 1.2e-07 31.7 0.0 2e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFH45923.1 - 3e-07 30.5 0.1 1.8e-05 24.8 0.0 2.3 1 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFH45923.1 - 4.4e-06 26.6 0.0 9.1e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KFH45923.1 - 0.0013 18.4 0.0 0.0037 16.9 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.1 KFH45923.1 - 0.0043 16.8 0.0 0.0074 16.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KFH45923.1 - 0.013 15.4 0.1 0.064 13.1 0.0 2.0 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 KFH45923.1 - 0.021 14.7 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Cg6151-P PF10233.4 KFH45924.1 - 8e-35 119.2 14.2 9.5e-35 118.9 9.8 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Cytochrom_B558a PF05038.8 KFH45924.1 - 0.42 10.2 5.6 0.76 9.3 3.9 1.5 1 1 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit BAGE PF08180.6 KFH45924.1 - 3 7.6 5.2 0.53 10.0 0.6 1.9 2 0 0 2 2 2 0 B melanoma antigen family RNase_H2-Ydr279 PF09468.5 KFH45925.1 - 1.6e-90 303.3 1.4 2.1e-90 303.0 1.0 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) VIT1 PF01988.14 KFH45925.1 - 0.58 9.6 2.3 1.2 8.5 1.6 1.4 1 0 0 1 1 1 0 VIT family ADH_zinc_N PF00107.21 KFH45926.1 - 7.8e-07 28.6 0.0 1.4e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFH45926.1 - 0.0072 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KFH45926.1 - 0.097 13.5 0.1 0.27 12.1 0.0 1.8 1 0 0 1 1 1 0 Zinc-binding dehydrogenase SNF2_N PF00176.18 KFH45928.1 - 2.2e-51 174.4 0.0 3.8e-51 173.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 KFH45928.1 - 6.3e-26 90.0 0.9 1.8e-25 88.5 0.6 1.9 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 KFH45928.1 - 1.3e-13 50.6 0.0 3.3e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFH45928.1 - 5.3e-05 23.1 0.2 0.0013 18.5 0.0 3.4 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit 2Fe-2S_thioredx PF01257.14 KFH45929.1 - 8e-60 200.6 0.0 1e-59 200.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin AMP-binding PF00501.23 KFH45930.1 - 1.2e-82 277.6 0.1 1.5e-82 277.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFH45930.1 - 4.7e-16 59.5 0.2 1.5e-15 57.9 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PhnI PF05861.7 KFH45930.1 - 0.062 11.8 0.0 0.095 11.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnI) Fungal_trans PF04082.13 KFH45931.1 - 3e-21 75.4 0.0 5e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain E1-E2_ATPase PF00122.15 KFH45932.1 - 9.7e-60 201.4 0.5 1.7e-59 200.6 0.3 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFH45932.1 - 7.3e-41 139.6 2.0 7.3e-41 139.6 1.4 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFH45932.1 - 1.7e-28 100.5 0.0 5.9e-28 98.7 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFH45932.1 - 9.5e-21 73.5 0.0 1.8e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KFH45932.1 - 2.2e-16 60.5 0.0 4.8e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFH45932.1 - 7.5e-05 22.1 0.7 0.0017 17.7 0.0 3.1 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KFH45932.1 - 0.0001 21.9 0.7 0.00015 21.4 0.1 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF202 PF02656.10 KFH45932.1 - 0.64 10.2 0.0 0.64 10.2 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF202) Abhydrolase_3 PF07859.8 KFH45933.1 - 3e-51 173.9 0.1 1.9e-50 171.3 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KFH45933.1 - 3.1e-08 32.8 0.5 7.8e-08 31.4 0.4 1.6 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 KFH45933.1 - 9.7e-05 21.6 0.0 0.056 12.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family CorA PF01544.13 KFH45934.1 - 0.0003 19.9 0.3 0.00074 18.6 0.2 1.7 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Ribosomal_L37 PF08561.5 KFH45934.1 - 0.00074 19.0 0.0 0.057 12.9 0.0 2.5 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L37 SBP PF03110.9 KFH45934.1 - 0.11 12.7 1.1 0.31 11.2 0.3 1.9 2 0 0 2 2 2 0 SBP domain Dna2 PF08696.6 KFH45935.1 - 2.4e-71 239.3 0.5 7.5e-71 237.7 0.0 2.0 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_12 PF13087.1 KFH45935.1 - 1.4e-51 174.7 0.0 2.5e-51 173.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KFH45935.1 - 8.9e-40 136.7 0.3 1.8e-18 67.0 0.0 2.8 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 KFH45935.1 - 4.8e-15 55.6 0.0 1.5e-14 54.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.12 KFH45935.1 - 2.4e-11 43.8 0.2 7.5e-10 38.9 0.1 2.9 3 0 0 3 3 3 1 Domain of unknown function DUF83 AAA_19 PF13245.1 KFH45935.1 - 2.3e-10 40.0 0.2 5.7e-10 38.8 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain PDDEXK_1 PF12705.2 KFH45935.1 - 1.2e-07 31.3 0.0 2.7e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.13 KFH45935.1 - 6.5e-06 25.8 0.2 0.28 10.6 0.1 3.5 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase MobB PF03205.9 KFH45935.1 - 9e-05 22.1 0.1 0.00032 20.4 0.0 1.9 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B Helicase_RecD PF05127.9 KFH45935.1 - 0.0003 20.4 0.0 0.0012 18.5 0.0 2.0 1 1 0 1 1 1 1 Helicase PIF1 PF05970.9 KFH45935.1 - 0.00038 19.4 0.0 0.036 13.0 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase CbiA PF01656.18 KFH45935.1 - 0.00092 18.6 0.0 0.0043 16.4 0.0 2.0 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.17 KFH45935.1 - 0.00096 18.6 0.2 0.0018 17.7 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain UvrD-helicase PF00580.16 KFH45935.1 - 0.002 17.4 0.3 0.0081 15.4 0.1 2.1 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_25 PF13481.1 KFH45935.1 - 0.004 16.5 0.0 0.081 12.3 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KFH45935.1 - 0.0059 16.6 0.2 0.02 14.9 0.0 1.9 2 0 0 2 2 1 1 AAA ATPase domain DUF911 PF06023.7 KFH45935.1 - 0.0078 15.4 0.0 0.025 13.7 0.0 1.8 1 1 0 1 1 1 1 Archaeal protein of unknown function (DUF911) AAA_22 PF13401.1 KFH45935.1 - 0.0091 16.1 0.0 0.25 11.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KFH45935.1 - 0.016 14.0 0.1 0.034 13.0 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.4 KFH45935.1 - 0.021 13.8 0.0 0.038 12.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Miro PF08477.8 KFH45935.1 - 0.03 14.7 0.0 0.15 12.5 0.0 2.2 2 0 0 2 2 1 0 Miro-like protein AAA_33 PF13671.1 KFH45935.1 - 0.043 13.6 0.1 0.28 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KFH45935.1 - 0.064 12.9 0.1 0.26 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ArgK PF03308.11 KFH45935.1 - 0.072 11.8 0.1 0.16 10.7 0.0 1.5 1 0 0 1 1 1 0 ArgK protein NTPase_1 PF03266.10 KFH45935.1 - 0.077 12.6 0.5 0.23 11.1 0.2 1.9 2 0 0 2 2 1 0 NTPase ResIII PF04851.10 KFH45935.1 - 0.078 12.8 0.0 0.29 10.9 0.0 1.9 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.24 KFH45935.1 - 0.1 12.8 0.1 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 KFH45935.1 - 0.12 11.8 0.0 0.33 10.3 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Bax1-I PF01027.15 KFH45936.1 - 7.8e-50 169.3 29.6 9.1e-50 169.1 20.5 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF4366 PF14283.1 KFH45937.1 - 0.048 13.0 0.3 9 5.6 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4366) DUF533 PF04391.7 KFH45937.1 - 0.43 9.9 14.3 0.056 12.8 2.0 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF533) DUF2910 PF11139.3 KFH45937.1 - 7.1 5.7 7.7 4.2 6.4 1.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2910) Ribosomal_S18 PF01084.15 KFH45938.1 - 1.9e-10 40.4 0.0 4.3e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S18 ORC6 PF05460.8 KFH45938.1 - 0.001 18.2 2.3 0.0013 17.9 1.6 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) TraF PF13728.1 KFH45938.1 - 0.071 12.5 0.5 0.12 11.8 0.4 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein Fungal_trans PF04082.13 KFH45939.1 - 0.055 12.3 0.0 0.12 11.2 0.0 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain WD40 PF00400.27 KFH45940.1 - 1.3e-06 28.0 4.6 0.0092 15.8 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat Nbas_N PF15492.1 KFH45940.1 - 0.017 14.2 0.0 0.088 11.9 0.0 2.1 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.7 KFH45940.1 - 0.037 11.8 0.0 0.05 11.4 0.0 1.1 1 0 0 1 1 1 0 IKI3 family Lipase_3 PF01764.20 KFH45941.1 - 2.2e-34 118.0 0.0 3.1e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.11 KFH45941.1 - 9e-05 22.2 0.0 0.00019 21.1 0.0 1.5 1 0 0 1 1 1 1 Lipase 3 N-terminal region Abhydrolase_5 PF12695.2 KFH45941.1 - 0.001 18.8 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFH45941.1 - 0.0024 17.7 0.5 0.0046 16.8 0.1 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family BCSC_C PF05420.6 KFH45941.1 - 0.0096 15.0 1.0 0.16 11.0 0.4 2.2 2 0 0 2 2 2 1 Cellulose synthase operon protein C C-terminus (BCSC_C) Thioesterase PF00975.15 KFH45941.1 - 0.018 15.2 0.1 0.029 14.5 0.1 1.2 1 0 0 1 1 1 0 Thioesterase domain DUF2974 PF11187.3 KFH45941.1 - 0.019 14.3 0.3 0.032 13.5 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Cutinase PF01083.17 KFH45941.1 - 0.031 14.0 0.3 0.078 12.7 0.2 1.6 1 1 0 1 1 1 0 Cutinase PE-PPE PF08237.6 KFH45941.1 - 0.1 12.0 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 PE-PPE domain Aldo_ket_red PF00248.16 KFH45942.1 - 5.8e-48 163.1 0.0 7.6e-48 162.7 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family DLIC PF05783.6 KFH45943.1 - 3.2e-30 105.2 0.0 6e-28 97.7 0.0 3.0 3 0 0 3 3 3 3 Dynein light intermediate chain (DLIC) Pyridox_ox_2 PF12900.2 KFH45944.1 - 8.7e-37 126.1 0.0 1.2e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase F-box-like PF12937.2 KFH45945.1 - 7.8e-11 41.5 0.6 7.4e-08 32.0 0.0 3.0 2 1 0 2 2 2 2 F-box-like F-box PF00646.28 KFH45945.1 - 0.006 16.2 5.2 0.27 10.9 0.1 3.1 3 0 0 3 3 3 2 F-box domain Stanniocalcin PF03298.8 KFH45946.1 - 0.0038 16.2 0.0 0.0056 15.7 0.0 1.3 1 1 0 1 1 1 1 Stanniocalcin family ABC_tran PF00005.22 KFH45947.1 - 6.1e-49 165.8 0.6 7.1e-23 81.4 0.0 3.3 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 KFH45947.1 - 1.7e-20 72.6 5.9 1.7e-20 72.6 4.1 3.8 4 1 1 5 5 3 1 ABC transporter AAA_21 PF13304.1 KFH45947.1 - 1.8e-18 67.5 0.5 7.5e-05 22.8 0.0 4.5 3 1 0 4 4 4 3 AAA domain SMC_N PF02463.14 KFH45947.1 - 1.5e-11 44.0 0.7 0.0037 16.5 0.0 4.4 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KFH45947.1 - 2.3e-08 34.8 1.0 0.015 16.1 0.1 3.1 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.1 KFH45947.1 - 8.5e-07 28.3 5.2 0.33 9.9 0.0 4.6 4 2 0 4 4 4 2 AAA ATPase domain Miro PF08477.8 KFH45947.1 - 1.5e-06 28.7 1.0 0.0081 16.6 0.0 2.9 3 0 0 3 3 2 2 Miro-like protein AAA_29 PF13555.1 KFH45947.1 - 3e-06 26.6 0.2 0.061 12.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KFH45947.1 - 9.3e-06 25.5 0.0 0.045 13.7 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase MobB PF03205.9 KFH45947.1 - 1.4e-05 24.7 1.8 0.24 11.0 0.1 3.4 2 1 1 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KFH45947.1 - 1.7e-05 24.9 0.5 0.023 14.6 0.1 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.1 KFH45947.1 - 2e-05 24.8 3.5 0.13 12.6 0.0 3.5 5 0 0 5 5 3 2 AAA domain DUF258 PF03193.11 KFH45947.1 - 4.6e-05 22.6 0.0 0.12 11.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KFH45947.1 - 5.8e-05 23.2 0.4 0.82 9.8 0.1 3.5 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KFH45947.1 - 8.2e-05 22.5 0.0 0.52 10.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 KFH45947.1 - 0.00012 22.0 3.5 0.02 14.8 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA PF00004.24 KFH45947.1 - 0.00016 21.8 0.1 0.39 10.9 0.1 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 KFH45947.1 - 0.00036 20.9 0.7 0.0065 16.8 0.0 4.7 5 0 0 5 5 5 2 AAA domain NACHT PF05729.7 KFH45947.1 - 0.00066 19.3 0.5 0.84 9.2 0.0 2.6 2 0 0 2 2 2 2 NACHT domain ArgK PF03308.11 KFH45947.1 - 0.00068 18.4 0.3 0.86 8.3 0.0 2.5 2 0 0 2 2 2 2 ArgK protein NTPase_1 PF03266.10 KFH45947.1 - 0.0013 18.4 0.1 0.31 10.7 0.0 2.9 2 0 0 2 2 2 1 NTPase SbcCD_C PF13558.1 KFH45947.1 - 0.0014 18.4 0.3 1.9 8.4 0.2 3.6 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.20 KFH45947.1 - 0.0016 18.0 0.0 0.58 9.6 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.1 KFH45947.1 - 0.0016 18.3 0.0 0.82 9.5 0.0 3.1 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.17 KFH45947.1 - 0.0063 16.6 0.0 4 7.6 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Dynamin_N PF00350.18 KFH45947.1 - 0.0066 16.2 8.7 1.3 8.7 0.0 3.8 3 1 0 3 3 3 2 Dynamin family AAA_10 PF12846.2 KFH45947.1 - 0.0082 15.6 0.0 3.6 6.9 0.1 3.1 3 0 0 3 3 3 1 AAA-like domain T2SE PF00437.15 KFH45947.1 - 0.0084 15.0 0.1 0.13 11.0 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.1 KFH45947.1 - 0.01 15.2 0.0 5.7 6.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 KFH45947.1 - 0.012 14.4 0.0 3.7 6.3 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.14 KFH45947.1 - 0.014 14.8 0.7 1.7 8.0 0.4 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 KFH45947.1 - 0.019 14.5 0.1 6.5 6.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KFH45947.1 - 0.029 14.1 0.3 7.6 6.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 KFH45947.1 - 0.069 12.6 0.1 14 5.1 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 KFH45947.1 - 0.83 9.4 8.7 0.65 9.7 0.1 3.6 4 0 0 4 4 4 0 Domain of unknown function DUF87 TPR_11 PF13414.1 KFH45948.1 - 1.8e-09 37.1 4.1 3.9e-07 29.6 0.2 4.2 3 1 1 4 4 4 1 TPR repeat TPR_2 PF07719.12 KFH45948.1 - 2e-09 36.6 5.6 0.00011 21.8 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFH45948.1 - 4e-07 29.8 9.7 0.0037 17.1 0.1 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFH45948.1 - 4.9e-07 29.9 1.2 0.048 14.0 0.0 4.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFH45948.1 - 5.9e-07 28.8 0.6 0.0019 17.7 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFH45948.1 - 1.6e-06 28.5 17.5 0.011 16.3 0.1 7.2 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFH45948.1 - 2.3e-05 24.2 2.0 33 5.0 0.0 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFH45948.1 - 0.0034 17.8 22.3 1.1 10.0 0.0 8.4 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFH45948.1 - 0.69 9.8 4.6 1.9 8.4 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Arb2 PF09757.4 KFH45949.1 - 1.2e-17 63.9 0.0 1.7e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Arb2 domain ESSS PF10183.4 KFH45951.1 - 1.4e-19 70.3 0.2 1.7e-19 70.1 0.2 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ThiF PF00899.16 KFH45952.1 - 3.6e-28 98.0 0.0 5.8e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 KFH45952.1 - 0.063 13.3 0.0 0.23 11.5 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pkinase PF00069.20 KFH45953.1 - 3.6e-18 65.6 0.0 7.8e-18 64.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH45953.1 - 4.5e-10 39.0 0.0 2e-09 36.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase EST1_DNA_bind PF10373.4 KFH45954.1 - 1.4e-14 53.9 0.0 1.5e-12 47.3 0.0 2.4 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain SQS_PSY PF00494.14 KFH45954.1 - 0.041 13.1 0.2 0.086 12.1 0.1 1.5 1 0 0 1 1 1 0 Squalene/phytoene synthase DUF605 PF04652.11 KFH45954.1 - 5 6.4 15.6 7.1 5.9 10.8 1.2 1 0 0 1 1 1 0 Vta1 like Ribosomal_L6 PF00347.18 KFH45956.1 - 1.1e-23 83.4 0.0 2.5e-11 43.9 0.0 3.2 3 1 0 3 3 3 2 Ribosomal protein L6 Cu_amine_oxid PF01179.15 KFH45957.1 - 7.6e-140 466.2 0.0 4.4e-139 463.7 0.0 1.8 1 1 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 KFH45957.1 - 3.8e-07 30.1 0.3 1e-06 28.7 0.1 1.9 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 KFH45957.1 - 2.8e-06 27.2 0.0 6.6e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain FUSC_2 PF13515.1 KFH45958.1 - 1.2e-13 51.0 32.7 5.1e-10 39.3 6.0 3.2 2 1 1 3 3 3 3 Fusaric acid resistance protein-like DUF2422 PF10337.4 KFH45958.1 - 6.9e-10 38.2 3.2 6.9e-10 38.2 2.2 3.3 2 1 1 3 3 3 2 Protein of unknown function (DUF2422) ALMT PF11744.3 KFH45958.1 - 0.00024 19.9 7.7 0.00024 19.9 5.3 2.4 2 0 0 2 2 2 1 Aluminium activated malate transporter Wzy_C PF04932.10 KFH45958.1 - 5.9 6.6 14.7 1.1 9.0 0.5 3.3 3 0 0 3 3 3 0 O-Antigen ligase Sugar_tr PF00083.19 KFH45959.1 - 5.8e-78 262.4 23.9 7.3e-78 262.1 16.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH45959.1 - 8.9e-17 60.8 47.8 4.2e-16 58.6 19.4 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily PIG-F PF06699.6 KFH45960.1 - 5.5e-55 186.2 2.1 6.7e-55 186.0 1.5 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F MnhB PF04039.8 KFH45960.1 - 0.36 10.8 9.3 0.27 11.3 0.5 2.5 2 1 1 3 3 3 0 Domain related to MnhB subunit of Na+/H+ antiporter Bacteriocin_IIc PF10439.4 KFH45960.1 - 0.86 9.7 6.8 0.76 9.9 1.4 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide zf-primase PF09329.6 KFH45961.1 - 1.4e-18 66.1 0.6 2.7e-18 65.2 0.4 1.5 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.20 KFH45961.1 - 0.047 13.5 0.0 0.098 12.5 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Bac_luciferase PF00296.15 KFH45962.1 - 3.4e-58 197.1 0.3 4.8e-58 196.7 0.2 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase HDV_ag PF01517.13 KFH45962.1 - 0.034 13.8 0.1 0.056 13.1 0.1 1.2 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen DASH_Duo1 PF08651.5 KFH45963.1 - 6.4e-27 92.9 0.2 9.6e-27 92.3 0.2 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 DinB PF05163.7 KFH45963.1 - 0.023 14.3 0.5 0.032 13.9 0.3 1.3 1 0 0 1 1 1 0 DinB family DUF4355 PF14265.1 KFH45963.1 - 0.078 12.9 11.4 0.11 12.4 7.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) DUF1682 PF07946.9 KFH45963.1 - 0.24 10.1 5.0 0.32 9.8 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Spermine_synth PF01564.12 KFH45964.1 - 5.8e-06 25.4 0.0 8.4e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_23 PF13489.1 KFH45964.1 - 0.0049 16.5 0.0 0.015 15.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ribosomal_S26e PF01283.14 KFH45965.1 - 1.9e-50 169.8 9.7 2.1e-50 169.7 6.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.2 KFH45965.1 - 0.037 14.4 1.0 1.1 9.6 0.4 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain Zn_ribbon_2 PF12674.2 KFH45965.1 - 0.081 13.2 0.5 6.4 7.1 0.0 2.2 1 1 1 2 2 2 0 Putative zinc ribbon domain DUF1918 PF08940.6 KFH45965.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) GFA PF04828.9 KFH45967.1 - 2.6e-12 46.4 5.5 1.9e-06 27.6 0.0 2.8 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.6 KFH45967.1 - 0.0003 20.5 0.1 0.33 10.8 0.0 2.8 2 0 0 2 2 2 2 Nin one binding (NOB1) Zn-ribbon like Nudix_N_2 PF14803.1 KFH45967.1 - 0.095 12.4 3.4 6.6 6.5 0.1 3.4 3 0 0 3 3 3 0 Nudix N-terminal zf-ribbon_3 PF13248.1 KFH45967.1 - 0.14 11.4 7.9 1 8.6 0.0 4.1 4 0 0 4 4 4 0 zinc-ribbon domain T2SI PF02501.12 KFH45967.1 - 0.16 11.9 0.4 8.1 6.4 0.0 2.3 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein I Ogr_Delta PF04606.7 KFH45967.1 - 0.25 11.0 8.3 0.12 12.0 1.0 3.2 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger Methyltransf_2 PF00891.13 KFH45968.1 - 1.1e-31 109.8 0.0 1.6e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.1 KFH45968.1 - 5.8e-05 22.7 0.0 0.0001 21.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH45968.1 - 0.014 15.9 0.0 0.026 15.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 KFH45968.1 - 0.093 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase DUF1614 PF07758.6 KFH45968.1 - 0.16 11.6 0.2 0.27 10.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1614) Cu_amine_oxid PF01179.15 KFH45969.1 - 2.8e-162 540.1 0.0 3.4e-162 539.9 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 KFH45969.1 - 5.9e-10 39.0 0.0 1.1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 KFH45969.1 - 0.011 15.7 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 Copper amine oxidase, N3 domain Glyco_hydro_2_C PF02836.12 KFH45971.1 - 1.8e-96 322.5 0.1 2.5e-96 322.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 KFH45971.1 - 6.7e-61 205.7 0.1 1.2e-60 204.9 0.1 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 KFH45971.1 - 2.5e-50 170.2 0.2 5.6e-50 169.1 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KFH45971.1 - 1.9e-10 41.1 0.4 1e-09 38.8 0.0 2.4 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Mpv17_PMP22 PF04117.7 KFH45972.1 - 7e-15 54.4 0.4 1.3e-14 53.5 0.2 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family MFS_1 PF07690.11 KFH45973.1 - 9.2e-29 100.2 20.5 1.9e-28 99.1 14.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1700 PF08006.6 KFH45973.1 - 0.29 10.4 1.4 1.3 8.3 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) PolyA_pol_RNAbd PF12627.2 KFH45974.1 - 0.00017 21.0 0.1 0.027 14.0 0.0 2.2 2 0 0 2 2 2 2 Probable RNA and SrmB- binding site of polymerase A Syntaxin_2 PF14523.1 KFH45974.1 - 0.0053 16.7 0.8 0.42 10.6 0.3 2.1 2 0 0 2 2 2 2 Syntaxin-like protein TilS PF09179.6 KFH45974.1 - 2.4 8.2 7.0 1.3 9.1 0.3 2.7 2 1 0 2 2 2 0 TilS substrate binding domain CENP-B_dimeris PF09026.5 KFH45975.1 - 1 9.6 5.8 1.4 9.2 4.0 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain BATS PF06968.8 KFH45976.1 - 1.2e-29 101.9 0.0 3.2e-29 100.6 0.0 1.7 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 KFH45976.1 - 3.5e-16 59.8 0.1 9.5e-16 58.4 0.1 1.8 2 0 0 2 2 2 1 Radical SAM superfamily ADH_zinc_N PF00107.21 KFH45977.1 - 3.3e-20 71.9 0.1 5.8e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFH45977.1 - 0.00018 22.3 0.1 0.00073 20.4 0.0 2.1 3 1 0 3 3 3 1 Zinc-binding dehydrogenase VRR_NUC PF08774.6 KFH45977.1 - 0.15 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 VRR-NUC domain Ribosomal_S10 PF00338.17 KFH45978.1 - 9.1e-29 99.1 0.5 1.1e-28 98.8 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Fibrillarin_2 PF10113.4 KFH45978.1 - 0.053 11.8 0.0 0.06 11.6 0.0 1.1 1 0 0 1 1 1 0 Fibrillarin-like archaeal protein AAA PF00004.24 KFH45979.1 - 3.4e-42 143.7 0.0 8.9e-42 142.4 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 KFH45979.1 - 4e-25 87.4 0.5 4.5e-24 84.1 0.2 2.7 2 1 1 3 3 3 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 KFH45979.1 - 4.7e-18 64.8 5.2 1.3e-17 63.3 3.2 2.1 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain RuvB_N PF05496.7 KFH45979.1 - 1.8e-06 27.1 0.0 2.8e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KFH45979.1 - 2.2e-06 28.4 0.1 1.4e-05 25.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 KFH45979.1 - 5.5e-06 25.3 0.0 1.2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_22 PF13401.1 KFH45979.1 - 1.6e-05 25.0 0.1 0.0065 16.6 0.0 2.7 2 1 1 3 3 2 1 AAA domain AAA_14 PF13173.1 KFH45979.1 - 1.7e-05 24.6 0.0 6.2e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFH45979.1 - 1.8e-05 24.4 0.0 0.00014 21.6 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KFH45979.1 - 2e-05 24.0 0.0 4.9e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 KFH45979.1 - 3.9e-05 23.7 0.0 0.0081 16.3 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_16 PF13191.1 KFH45979.1 - 8.9e-05 22.5 0.0 0.0031 17.5 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 KFH45979.1 - 0.00024 20.1 0.1 0.0012 17.8 0.0 2.2 2 1 1 3 3 3 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 KFH45979.1 - 0.00057 19.7 0.0 0.002 17.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain PrkA PF06798.7 KFH45979.1 - 0.00065 19.0 1.1 0.0014 17.9 0.7 1.6 1 1 0 1 1 1 1 PrkA serine protein kinase C-terminal domain AAA_25 PF13481.1 KFH45979.1 - 0.00085 18.7 0.1 0.21 10.9 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 KFH45979.1 - 0.0021 18.0 0.0 0.0069 16.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.1 KFH45979.1 - 0.0055 16.3 0.4 0.024 14.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KFH45979.1 - 0.0091 15.1 0.0 0.076 12.1 0.0 2.2 1 1 1 2 2 2 1 Zeta toxin AAA_18 PF13238.1 KFH45979.1 - 0.0092 16.2 0.0 0.026 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KFH45979.1 - 0.019 14.1 0.0 0.062 12.4 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KFH45979.1 - 0.022 14.5 0.0 0.073 12.8 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_21 PF13304.1 KFH45979.1 - 0.026 14.4 0.2 2.5 7.9 0.0 2.3 1 1 1 2 2 2 0 AAA domain NACHT PF05729.7 KFH45979.1 - 0.028 14.0 0.0 0.63 9.6 0.0 2.4 1 1 0 2 2 2 0 NACHT domain PhoH PF02562.11 KFH45979.1 - 0.03 13.5 0.4 0.085 12.0 0.1 1.8 2 0 0 2 2 2 0 PhoH-like protein Arch_ATPase PF01637.13 KFH45979.1 - 0.063 12.9 0.5 0.68 9.5 0.0 2.6 2 2 1 3 3 3 0 Archaeal ATPase Parvo_NS1 PF01057.12 KFH45979.1 - 0.089 11.6 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Torsin PF06309.6 KFH45979.1 - 0.091 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Torsin Sigma54_activ_2 PF14532.1 KFH45979.1 - 0.092 12.7 0.3 0.43 10.6 0.0 2.2 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.1 KFH45979.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain MAPEG PF01124.13 KFH45980.1 - 4e-11 42.6 4.4 6.4e-11 41.9 2.9 1.5 1 1 1 2 2 2 1 MAPEG family COX8 PF02285.10 KFH45980.1 - 0.062 12.8 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIII Na_H_Exchanger PF00999.16 KFH45981.1 - 9.9e-37 126.3 13.0 1.5e-36 125.7 9.0 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 KFH45981.1 - 0.048 13.5 0.1 0.048 13.5 0.1 3.0 3 0 0 3 3 3 0 YrhC-like protein DUF3267 PF11667.3 KFH45981.1 - 0.056 13.6 2.4 0.21 11.8 1.7 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3267) Phage_lysozyme PF00959.14 KFH45982.1 - 4.7e-06 26.8 0.0 5.8e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Phage lysozyme Prefoldin_2 PF01920.15 KFH45983.1 - 2e-19 69.2 10.2 4.1e-15 55.4 1.6 2.0 2 0 0 2 2 2 2 Prefoldin subunit Prefoldin PF02996.12 KFH45983.1 - 0.0031 17.1 5.4 0.011 15.4 0.7 2.2 2 0 0 2 2 2 1 Prefoldin subunit COG5 PF10392.4 KFH45983.1 - 0.0031 17.4 0.4 0.076 12.9 0.0 2.1 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Fez1 PF06818.10 KFH45983.1 - 0.0061 16.6 3.2 0.008 16.2 0.2 2.0 2 0 0 2 2 2 1 Fez1 Prefoldin_3 PF13758.1 KFH45983.1 - 0.016 14.9 1.1 0.062 13.0 0.8 2.0 1 1 0 1 1 1 0 Prefoldin subunit DivIC PF04977.10 KFH45983.1 - 0.022 14.2 10.3 0.59 9.6 0.7 3.2 3 0 0 3 3 3 0 Septum formation initiator Macoilin PF09726.4 KFH45983.1 - 0.022 13.0 4.0 0.029 12.6 2.7 1.1 1 0 0 1 1 1 0 Transmembrane protein IncA PF04156.9 KFH45983.1 - 0.035 13.7 9.9 0.12 11.9 1.0 2.1 1 1 1 2 2 2 0 IncA protein ADIP PF11559.3 KFH45983.1 - 0.036 13.9 3.9 0.18 11.6 0.2 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Spc24 PF08286.6 KFH45983.1 - 0.076 12.7 3.4 3.9 7.1 0.2 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 TPR_MLP1_2 PF07926.7 KFH45983.1 - 0.18 11.5 7.5 0.74 9.5 5.1 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.2 KFH45983.1 - 0.29 10.9 9.8 1.5 8.6 1.5 2.2 1 1 0 2 2 2 0 Tropomyosin like DUF3375 PF11855.3 KFH45983.1 - 0.3 9.7 0.1 0.3 9.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3375) DUF4164 PF13747.1 KFH45983.1 - 0.39 10.8 5.6 4.9 7.3 0.2 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF4164) Sas10_Utp3 PF04000.10 KFH45983.1 - 0.43 10.8 2.8 1.9 8.7 0.2 2.4 3 0 0 3 3 2 0 Sas10/Utp3/C1D family DUF4201 PF13870.1 KFH45983.1 - 0.44 9.9 5.8 1.3 8.3 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) zf-C4H2 PF10146.4 KFH45983.1 - 0.48 10.4 3.1 0.38 10.7 1.1 1.6 1 1 0 1 1 1 0 Zinc finger-containing protein NPV_P10 PF05531.7 KFH45983.1 - 0.48 10.6 4.3 3.7 7.8 0.6 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein MutS_IV PF05190.13 KFH45983.1 - 0.49 10.6 2.9 4.1 7.6 0.1 2.8 2 1 1 3 3 3 0 MutS family domain IV V-ATPase_C PF03223.10 KFH45983.1 - 0.5 9.2 3.1 2 7.2 2.1 1.9 1 1 0 1 1 1 0 V-ATPase subunit C Mnd1 PF03962.10 KFH45983.1 - 0.52 9.9 6.8 5.1 6.7 0.5 2.1 1 1 1 2 2 2 0 Mnd1 family HALZ PF02183.13 KFH45983.1 - 0.58 9.9 10.3 3.3 7.5 0.1 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF1978 PF09321.5 KFH45983.1 - 0.61 9.4 4.9 0.78 9.1 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) YgaB PF14182.1 KFH45983.1 - 0.65 10.2 8.5 0.24 11.6 2.3 2.1 2 0 0 2 2 2 0 YgaB-like protein Filament PF00038.16 KFH45983.1 - 0.68 9.3 6.4 19 4.6 4.5 2.0 1 1 0 1 1 1 0 Intermediate filament protein DUF2968 PF11180.3 KFH45983.1 - 0.71 9.2 8.1 0.29 10.5 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Lzipper-MIP1 PF14389.1 KFH45983.1 - 0.86 9.7 5.1 1.9 8.6 0.8 2.2 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Rootletin PF15035.1 KFH45983.1 - 1.4 8.8 6.0 15 5.5 4.2 2.1 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion FlxA PF14282.1 KFH45983.1 - 1.5 8.8 9.6 6.4 6.7 1.0 2.6 3 0 0 3 3 2 0 FlxA-like protein TBPIP PF07106.8 KFH45983.1 - 1.5 8.3 8.1 4.7 6.7 1.0 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Cep57_MT_bd PF06657.8 KFH45983.1 - 1.7 8.6 7.0 8.9 6.3 0.7 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 FliJ PF02050.11 KFH45983.1 - 1.8 8.6 8.5 7.1 6.6 0.9 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein DUF342 PF03961.8 KFH45983.1 - 1.9 6.8 8.0 15 3.8 5.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Tup_N PF08581.5 KFH45983.1 - 2 8.6 6.2 55 4.0 1.2 3.1 2 1 0 2 2 2 0 Tup N-terminal DUF964 PF06133.6 KFH45983.1 - 2.1 8.3 8.7 0.98 9.4 0.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF964) Spectrin PF00435.16 KFH45983.1 - 2.5 8.4 7.3 5 7.4 0.1 2.4 1 1 1 3 3 3 0 Spectrin repeat Spc7 PF08317.6 KFH45983.1 - 3.3 6.2 8.3 15 4.0 5.8 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.4 KFH45983.1 - 9.5 5.0 8.2 22 3.8 5.7 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FAD_binding_3 PF01494.14 KFH45984.1 - 3.3e-17 62.5 0.3 1e-09 37.9 0.0 2.3 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KFH45984.1 - 0.0012 18.8 0.0 0.0029 17.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFH45984.1 - 0.0026 16.7 1.5 0.014 14.2 0.2 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KFH45984.1 - 0.0053 16.8 0.1 0.027 14.5 0.1 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KFH45984.1 - 0.01 15.2 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 KFH45984.1 - 0.011 16.1 0.0 0.048 14.0 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KFH45984.1 - 0.037 13.6 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 KFH45984.1 - 0.059 13.2 0.0 0.094 12.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.19 KFH45985.1 - 1.9e-13 49.8 7.7 2.1e-13 49.6 5.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH45985.1 - 0.0032 16.2 0.1 0.0046 15.7 0.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1129 PF06570.6 KFH45985.1 - 0.15 11.3 2.6 0.2 10.9 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) GWT1 PF06423.7 KFH45985.1 - 0.19 11.8 3.3 0.053 13.6 0.4 1.4 2 0 0 2 2 2 0 GWT1 An_peroxidase PF03098.10 KFH45986.1 - 7.8e-96 321.5 0.0 1.4e-93 314.0 0.0 2.3 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 KFH45986.1 - 3.5e-06 25.8 0.1 6.3e-05 21.6 0.0 2.2 2 0 0 2 2 2 1 Cytochrome P450 TRI12 PF06609.8 KFH45987.1 - 3.1e-59 200.7 21.2 4.1e-59 200.3 14.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KFH45987.1 - 7e-20 71.0 55.1 3.1e-19 68.9 34.7 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Fig1 PF12351.3 KFH45988.1 - 1e-57 195.0 4.1 1e-57 195.0 2.8 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 KFH45988.1 - 2.7e-10 40.1 5.9 4.3e-10 39.5 4.1 1.3 1 1 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.8 KFH45988.1 - 3.3e-05 22.9 8.1 3.3e-05 22.9 5.6 1.9 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) MLTD_N PF06474.7 KFH45988.1 - 0.74 10.0 3.4 3.4 7.9 2.4 2.2 1 0 0 1 1 1 0 MltD lipid attachment motif LPAM_2 PF13627.1 KFH45988.1 - 1.3 8.7 6.3 9.6 6.0 4.4 2.6 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site DUF202 PF02656.10 KFH45988.1 - 6.1 7.1 13.0 7.1 6.9 2.9 3.6 1 1 1 2 2 2 0 Domain of unknown function (DUF202) DUF1993 PF09351.5 KFH45989.1 - 5.7e-43 146.6 0.0 6.4e-43 146.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) HMG_CoA_synt_C PF08540.5 KFH45989.1 - 0.028 13.9 0.0 0.034 13.6 0.0 1.1 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase C terminal Borrelia_P13 PF05628.7 KFH45989.1 - 0.059 13.1 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 Borrelia membrane protein P13 JAB PF01398.16 KFH45990.1 - 1.6e-13 50.3 0.0 2.9e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 KFH45990.1 - 1.7e-07 31.1 0.0 3.6e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.1 KFH45990.1 - 3.3e-06 26.5 0.0 9.8e-06 25.0 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Fungal_trans PF04082.13 KFH45991.1 - 0.00073 18.4 1.7 0.0042 15.9 1.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH45991.1 - 0.0084 15.9 10.3 0.014 15.3 7.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.22 KFH45992.1 - 5.1e-60 199.2 3.2 2e-21 75.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.13 KFH45994.1 - 1.2e-13 50.5 0.3 2.1e-13 49.7 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH45994.1 - 3.9e-07 29.8 8.8 8.4e-07 28.7 6.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_A_type_inc PF04508.7 KFH45994.1 - 0.14 12.0 0.6 0.48 10.3 0.4 2.0 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DUF2039 PF10217.4 KFH45994.1 - 1.3 9.1 5.9 2.5 8.1 4.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) MFS_1 PF07690.11 KFH45995.1 - 2.4e-37 128.4 35.8 2.4e-37 128.4 24.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 KFH45995.1 - 0.43 8.5 0.0 0.43 8.5 0.0 3.1 4 0 0 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family DUF751 PF05421.6 KFH45995.1 - 0.58 10.4 0.1 0.58 10.4 0.1 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF751) Sugar_tr PF00083.19 KFH45996.1 - 2.3e-35 122.0 6.1 3.1e-35 121.6 4.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH45996.1 - 1.6e-17 63.2 14.4 2.1e-17 62.9 10.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KFH45996.1 - 0.00029 19.1 3.5 0.0004 18.7 2.1 1.4 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 KFH45996.1 - 0.0072 14.7 0.6 0.0072 14.7 0.4 2.0 2 0 0 2 2 2 1 MFS/sugar transport protein Polysacc_synt_C PF14667.1 KFH45996.1 - 0.057 13.2 4.2 0.05 13.4 1.3 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain DUF2583 PF10762.4 KFH45996.1 - 0.62 10.2 2.5 0.36 10.9 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) adh_short PF00106.20 KFH45997.1 - 1.6e-08 34.6 0.0 2.7e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Glyoxalase_2 PF12681.2 KFH45998.1 - 5.9e-12 46.1 0.0 7.2e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KFH45998.1 - 3.5e-07 30.2 0.0 4.9e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MFS_1 PF07690.11 KFH45999.1 - 2.2e-10 39.7 37.5 4.2e-10 38.8 26.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 KFH45999.1 - 1.8e-07 30.7 5.7 1.8e-07 30.7 4.0 3.2 3 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 zf-FPG_IleRS PF06827.9 KFH46001.1 - 0.014 15.0 3.1 0.027 14.1 2.1 1.5 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS SMC_N PF02463.14 KFH46002.1 - 1.3e-70 237.0 31.3 4e-70 235.4 21.7 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KFH46002.1 - 1.4e-27 96.0 0.0 4.9e-27 94.2 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KFH46002.1 - 1.4e-13 51.5 4.3 1.7e-05 24.9 0.0 3.5 2 1 0 2 2 2 2 AAA domain TPR_MLP1_2 PF07926.7 KFH46002.1 - 7.8e-05 22.4 3.7 7.8e-05 22.4 2.6 8.6 3 3 5 8 8 8 3 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.2 KFH46002.1 - 0.00011 22.0 14.1 0.00011 22.0 9.8 7.5 3 3 3 7 7 7 1 Tropomyosin like AAA_29 PF13555.1 KFH46002.1 - 0.00019 20.8 0.0 0.00044 19.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 KFH46002.1 - 0.19 10.8 30.3 0.1 11.7 0.4 4.8 3 2 2 5 5 5 0 Reovirus sigma C capsid protein IncA PF04156.9 KFH46002.1 - 9.3 5.7 130.5 0.023 14.3 9.0 7.9 3 2 5 8 8 8 0 IncA protein Alpha-amylase PF00128.19 KFH46003.1 - 8.2e-98 327.6 0.0 1.2e-97 327.1 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF4434 PF14488.1 KFH46003.1 - 0.0051 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4434) hDGE_amylase PF14701.1 KFH46003.1 - 0.014 14.2 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme DUF2204 PF09970.4 KFH46004.1 - 0.023 14.1 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) Glyco_hydro_81 PF03639.8 KFH46005.1 - 1.9e-73 247.6 1.7 2.1e-73 247.5 1.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Abhydrolase_3 PF07859.8 KFH46006.1 - 4.4e-52 176.7 0.3 6e-52 176.2 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KFH46006.1 - 2.9e-08 33.8 3.9 4e-08 33.4 2.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KFH46006.1 - 8.9e-07 27.9 0.2 2.2e-06 26.6 0.2 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KFH46006.1 - 0.00049 19.8 0.2 0.0017 18.1 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KFH46006.1 - 0.022 13.2 0.1 1.3 7.4 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 KFH46006.1 - 0.056 12.6 0.0 0.49 9.5 0.0 2.1 1 1 0 1 1 1 0 Prolyl oligopeptidase family BAAT_C PF08840.6 KFH46006.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal APH PF01636.18 KFH46007.1 - 9e-16 58.3 0.0 4.1e-15 56.1 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family PrpR_N PF06506.6 KFH46007.1 - 0.12 11.8 0.0 0.41 10.0 0.0 1.7 2 0 0 2 2 2 0 Propionate catabolism activator Glyco_hydro_18 PF00704.23 KFH46008.1 - 1.2e-96 324.2 0.9 1.3e-96 324.0 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF2274 PF10038.4 KFH46008.1 - 0.12 12.5 0.1 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2274) Sec34 PF04136.10 KFH46009.1 - 6.8e-31 107.1 1.2 1.3e-30 106.1 0.2 2.0 2 0 0 2 2 2 1 Sec34-like family DUF948 PF06103.6 KFH46009.1 - 0.094 12.5 1.4 6.5 6.6 0.1 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Epimerase PF01370.16 KFH46010.1 - 1.1e-23 83.9 0.0 2.5e-23 82.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFH46010.1 - 7.5e-11 42.3 0.0 1.6e-10 41.3 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KFH46010.1 - 5.6e-09 35.2 0.0 1.6e-08 33.7 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 KFH46010.1 - 4.9e-08 32.0 0.0 1e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KFH46010.1 - 1.4e-06 28.3 1.2 3.3e-06 27.1 0.8 1.7 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 KFH46010.1 - 0.0054 15.6 0.2 0.015 14.2 0.2 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 KFH46010.1 - 0.0069 16.0 0.7 0.013 15.1 0.5 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 KFH46010.1 - 0.012 14.9 0.0 0.03 13.5 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family SEEK1 PF15357.1 KFH46010.1 - 0.027 14.3 0.1 0.053 13.4 0.1 1.4 1 0 0 1 1 1 0 Psoriasis susceptibility 1 candidate 1 Polysacc_synt_2 PF02719.10 KFH46010.1 - 0.18 10.6 0.1 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein p450 PF00067.17 KFH46011.1 - 2.9e-62 210.6 0.0 3.9e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ubiquitin PF00240.18 KFH46012.1 - 1.7e-34 117.0 0.9 2.7e-34 116.3 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 KFH46012.1 - 7.6e-26 89.6 0.7 1.6e-25 88.6 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 KFH46012.1 - 6.1e-20 70.6 0.7 1e-19 69.9 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KFH46012.1 - 9.3e-06 25.8 0.2 3.9e-05 23.8 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KFH46012.1 - 0.00012 21.8 0.1 0.00019 21.1 0.0 1.3 1 1 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 KFH46012.1 - 0.00072 19.4 0.7 0.0015 18.4 0.5 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KFH46012.1 - 0.0036 17.4 0.5 0.0049 17.0 0.3 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Terminase_GpA PF05876.7 KFH46012.1 - 0.046 12.0 0.1 0.045 12.0 0.1 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) DUF2870 PF11069.3 KFH46012.1 - 0.066 13.2 0.7 0.11 12.4 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 KFH46012.1 - 0.067 11.4 2.3 1.9 6.7 0.1 2.1 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain DUF971 PF06155.7 KFH46012.1 - 0.13 12.6 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF971) Amidase PF01425.16 KFH46014.1 - 1.2e-50 172.6 0.1 5.9e-50 170.4 0.1 1.9 1 1 0 1 1 1 1 Amidase DUF1237 PF06824.6 KFH46015.1 - 5.1e-19 68.1 0.0 3e-18 65.6 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1237) TMF_DNA_bd PF12329.3 KFH46016.1 - 0.00085 19.0 33.4 0.0098 15.6 0.0 6.9 5 2 2 7 7 7 1 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.1 KFH46016.1 - 0.00088 17.8 13.2 0.0066 14.9 4.1 3.5 2 1 1 3 3 3 1 AAA domain DUF603 PF04645.7 KFH46016.1 - 0.0095 15.8 1.2 0.0095 15.8 0.9 3.1 2 1 1 3 3 3 1 Protein of unknown function, DUF603 Spc7 PF08317.6 KFH46016.1 - 0.039 12.6 23.8 0.17 10.5 1.4 4.3 3 1 1 4 4 4 0 Spc7 kinetochore protein Tropomyosin_1 PF12718.2 KFH46016.1 - 0.12 12.1 30.9 1.5 8.6 1.0 4.5 3 1 1 4 4 4 0 Tropomyosin like Reo_sigmaC PF04582.7 KFH46016.1 - 0.13 11.3 12.7 0.075 12.1 0.5 3.9 2 1 1 4 4 4 0 Reovirus sigma C capsid protein Phage_GP20 PF06810.6 KFH46016.1 - 0.17 11.3 19.7 0.12 11.7 1.2 5.3 4 1 2 6 6 6 0 Phage minor structural protein GP20 APG6 PF04111.7 KFH46016.1 - 0.19 10.7 25.7 0.49 9.3 3.9 4.0 3 1 1 4 4 4 0 Autophagy protein Apg6 FlaC_arch PF05377.6 KFH46016.1 - 0.29 11.0 17.6 0.69 9.8 0.1 6.3 8 1 0 8 8 6 0 Flagella accessory protein C (FlaC) IncA PF04156.9 KFH46016.1 - 0.38 10.3 40.5 0.039 13.5 0.6 4.9 3 2 1 4 4 4 0 IncA protein MscS_porin PF12795.2 KFH46016.1 - 0.44 9.8 30.7 0.038 13.3 0.6 4.1 3 1 0 3 3 3 0 Mechanosensitive ion channel porin domain Gp58 PF07902.6 KFH46016.1 - 0.47 8.6 13.1 0.63 8.1 0.6 3.1 3 0 0 3 3 3 0 gp58-like protein TBPIP PF07106.8 KFH46016.1 - 0.61 9.6 19.3 4.5 6.7 0.7 4.9 3 1 2 5 5 5 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FlxA PF14282.1 KFH46016.1 - 0.85 9.5 13.6 0.086 12.7 0.3 3.6 3 1 0 3 3 3 0 FlxA-like protein DUF1664 PF07889.7 KFH46016.1 - 1.2 8.8 16.8 5.5 6.7 0.1 5.1 4 2 2 6 6 6 0 Protein of unknown function (DUF1664) FemAB PF02388.11 KFH46016.1 - 1.9 7.0 6.4 0.91 8.1 0.8 2.6 2 0 0 2 2 2 0 FemAB family Prefoldin PF02996.12 KFH46016.1 - 2.1 7.9 20.0 3 7.4 0.1 6.5 6 2 0 7 7 6 0 Prefoldin subunit Atg14 PF10186.4 KFH46016.1 - 7.8 5.3 30.7 0.46 9.3 0.1 4.1 3 1 1 4 4 4 0 UV radiation resistance protein and autophagy-related subunit 14 YPEB PF14620.1 KFH46016.1 - 9.4 5.1 9.8 3.2 6.6 0.3 3.6 3 1 1 4 4 4 0 YpeB sporulation CAP PF00188.21 KFH46018.1 - 6.4e-13 49.2 0.5 8.7e-13 48.8 0.3 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family MFS_1 PF07690.11 KFH46019.1 - 4.5e-30 104.5 24.2 4.5e-30 104.5 16.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily RPAP1_N PF08621.5 KFH46019.1 - 0.0096 15.4 0.2 0.022 14.3 0.1 1.6 1 0 0 1 1 1 1 RPAP1-like, N-terminal MARVEL PF01284.18 KFH46021.1 - 7.8e-06 25.7 14.2 3.2e-05 23.7 9.8 2.1 1 1 0 1 1 1 1 Membrane-associating domain Clc-like PF07062.7 KFH46021.1 - 6.6 5.9 10.7 0.16 11.1 1.8 2.1 2 1 0 2 2 2 0 Clc-like Glyco_hydro_43 PF04616.9 KFH46022.1 - 6.6e-106 353.5 0.2 1.1e-105 352.8 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF3330 PF11809.3 KFH46022.1 - 0.064 13.1 0.4 0.4 10.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3330) RCC1 PF00415.13 KFH46023.1 - 2.1e-27 95.0 5.2 3.1e-05 24.0 0.0 7.1 6 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KFH46023.1 - 3.1e-09 36.1 2.2 9.1e-07 28.3 0.0 7.8 9 1 0 9 9 9 3 Regulator of chromosome condensation (RCC1) repeat WSC PF01822.14 KFH46025.1 - 2.7e-10 40.0 6.1 2.7e-10 40.0 4.2 2.3 2 0 0 2 2 2 1 WSC domain Trypan_PARP PF05887.6 KFH46025.1 - 4.4e-05 23.3 55.7 4.4e-05 23.3 38.6 4.5 3 1 1 4 4 4 1 Procyclic acidic repetitive protein (PARP) Peptidase_S8 PF00082.17 KFH46026.1 - 1.4e-43 149.1 6.9 1.9e-43 148.6 4.8 1.1 1 0 0 1 1 1 1 Subtilase family AlaDh_PNT_N PF05222.10 KFH46027.1 - 3.9e-19 68.9 0.0 7.1e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 KFH46027.1 - 1e-06 28.4 0.0 1.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Fungal_trans PF04082.13 KFH46028.1 - 3.8e-28 98.0 1.9 6.7e-28 97.2 1.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Arginase PF00491.16 KFH46029.1 - 2.2e-75 253.5 0.3 2.6e-75 253.2 0.2 1.0 1 0 0 1 1 1 1 Arginase family Sugar_tr PF00083.19 KFH46030.1 - 3.2e-73 246.8 17.8 4.6e-73 246.3 12.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH46030.1 - 8.6e-19 67.4 60.5 7.9e-12 44.5 16.9 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily Folate_carrier PF01770.13 KFH46030.1 - 1.5e-05 23.7 0.0 2.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Reduced folate carrier MFS_2 PF13347.1 KFH46030.1 - 2.5e-05 22.8 21.0 0.0019 16.6 0.4 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein Ftsk_gamma PF09397.5 KFH46032.1 - 0.097 12.3 0.2 0.28 10.9 0.0 1.8 2 0 0 2 2 2 0 Ftsk gamma domain 4HBT PF03061.17 KFH46033.1 - 9.6e-06 25.6 0.4 0.014 15.4 0.1 2.5 2 0 0 2 2 2 2 Thioesterase superfamily bZIP_1 PF00170.16 KFH46034.1 - 0.0069 16.3 5.9 0.013 15.4 4.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFH46034.1 - 0.0089 15.8 8.1 0.016 15.0 5.6 1.3 1 0 0 1 1 1 1 Basic region leucine zipper RINT1_TIP1 PF04437.8 KFH46035.1 - 6.9e-84 282.1 0.0 2.3e-83 280.4 0.0 1.8 1 1 0 1 1 1 1 RINT-1 / TIP-1 family DUF2939 PF11159.3 KFH46035.1 - 0.037 14.2 1.3 2.1 8.6 0.0 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) FUSC PF04632.7 KFH46035.1 - 3.3 6.0 10.0 6.7 5.0 6.9 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4164 PF13747.1 KFH46035.1 - 6 7.0 13.6 1.6 8.9 4.6 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DUF3562 PF12085.3 KFH46035.1 - 8 6.3 9.5 1.7 8.5 0.4 4.0 3 2 2 5 5 5 0 Protein of unknown function (DUF3562) Microtub_assoc PF07989.6 KFH46036.1 - 1e-19 70.0 8.9 1e-19 70.0 6.1 7.8 7 2 0 8 8 8 1 Microtubule associated Mto2_bdg PF12808.2 KFH46036.1 - 1.2e-11 44.5 10.5 1.2e-11 44.5 7.2 13.1 13 3 1 14 14 14 1 Micro-tubular organiser Mto1 C-term Mto2-binding region Reo_sigmaC PF04582.7 KFH46036.1 - 0.036 13.2 41.3 0.011 14.8 2.8 5.4 5 1 1 6 6 6 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 KFH46036.1 - 0.041 14.1 0.4 0.041 14.1 0.3 6.2 4 1 1 6 6 6 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 KFH46036.1 - 1.6 8.5 41.5 0.54 10.0 0.3 5.8 3 1 3 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.5 KFH46036.1 - 2.7 8.0 74.1 0.38 10.8 7.5 7.3 5 2 2 7 7 7 0 Fibrinogen alpha/beta chain family BcrAD_BadFG PF01869.15 KFH46037.1 - 1.1e-20 74.0 0.4 1.1e-19 70.8 0.1 2.5 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family SIS_2 PF13580.1 KFH46037.1 - 0.00012 21.7 0.0 0.0016 18.1 0.0 2.6 1 1 0 1 1 1 1 SIS domain SIS PF01380.17 KFH46037.1 - 0.019 14.5 0.1 0.24 10.9 0.0 2.4 2 0 0 2 2 2 0 SIS domain zf-CCCH PF00642.19 KFH46038.1 - 2.6e-06 26.9 2.0 4.8e-06 26.1 1.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nucleoporin_FG PF13634.1 KFH46038.1 - 5.6e-05 23.3 174.4 31 4.8 37.0 5.6 2 1 2 4 4 4 1 Nucleoporin FG repeat region HisKA_3 PF07730.8 KFH46038.1 - 0.43 10.9 1.3 0.79 10.1 0.9 1.4 1 0 0 1 1 1 0 Histidine kinase Cyclase PF04199.8 KFH46039.1 - 2.2e-14 53.5 0.0 2.9e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Fungal_trans PF04082.13 KFH46040.1 - 0.00054 18.9 0.0 0.001 18.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH46040.1 - 3.5 7.6 11.4 0.24 11.3 4.3 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain ELYS PF13934.1 KFH46042.1 - 8.2e-64 215.4 0.9 9.5e-64 215.2 0.6 1.0 1 0 0 1 1 1 1 Nuclear pore complex assembly LVIVD PF08309.6 KFH46043.1 - 9.8e-10 37.2 0.0 0.0055 15.6 0.0 4.0 3 0 0 3 3 3 3 LVIVD repeat DUF4245 PF14030.1 KFH46043.1 - 0.057 13.1 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) CUE PF02845.11 KFH46044.1 - 4.1e-09 35.7 0.0 8.7e-09 34.7 0.0 1.6 1 0 0 1 1 1 1 CUE domain PAF-AH_p_II PF03403.8 KFH46045.1 - 3e-10 38.9 0.0 0.00011 20.6 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 KFH46045.1 - 9e-10 38.4 0.1 1.5e-09 37.8 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFH46045.1 - 3.7e-07 30.2 0.7 5.3e-07 29.7 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFH46045.1 - 0.0069 15.9 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KFH46045.1 - 0.036 13.9 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase K1 PF02960.9 KFH46046.1 - 0.0079 16.2 0.0 0.024 14.6 0.0 1.8 1 0 0 1 1 1 1 K1 glycoprotein JCAD PF15351.1 KFH46047.1 - 0.21 9.1 2.5 0.14 9.6 0.1 1.7 2 0 0 2 2 2 0 Junctional protein associated with coronary artery disease Glyco_transf_90 PF05686.7 KFH46050.1 - 1.9e-12 46.6 7.0 2.1e-10 39.8 0.0 3.2 3 0 0 3 3 3 3 Glycosyl transferase family 90 Nop PF01798.13 KFH46051.1 - 2.5e-49 166.4 0.1 4.6e-49 165.5 0.1 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOP5NT PF08156.8 KFH46051.1 - 3e-19 68.9 0.2 3e-19 68.9 0.1 2.5 2 0 0 2 2 2 1 NOP5NT (NUC127) domain NOSIC PF08060.8 KFH46051.1 - 7.3e-19 67.3 0.3 1.3e-18 66.5 0.2 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain RNA_polI_A34 PF08208.6 KFH46051.1 - 0.017 14.7 27.3 0.032 13.9 18.9 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 GAGA_bind PF06217.7 KFH46051.1 - 1.1 9.1 13.3 2.3 8.1 9.2 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Fungal_trans_2 PF11951.3 KFH46052.1 - 7.7e-57 192.6 0.1 1.3e-56 191.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH46052.1 - 1.2e-09 37.8 31.2 7.1e-05 22.6 5.8 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.4 KFH46052.1 - 0.12 10.5 29.1 0.17 10.0 20.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 vMSA PF00695.14 KFH46052.1 - 4.6 6.3 14.7 12 5.0 10.2 1.6 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Cellulase PF00150.13 KFH46053.1 - 6.6e-17 61.6 2.0 2.2e-16 59.8 1.4 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AAA_33 PF13671.1 KFH46054.1 - 1.7 8.4 4.7 31 4.4 1.9 2.1 1 1 1 2 2 2 0 AAA domain HECT PF00632.20 KFH46055.1 - 6.3e-72 242.3 0.0 8.8e-72 241.9 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Gpi16 PF04113.9 KFH46057.1 - 1.8e-231 769.0 0.0 2.3e-231 768.7 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component DUF4185 PF13810.1 KFH46058.1 - 9.2e-08 31.3 3.0 1.5e-07 30.6 0.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4185) zf-U1 PF06220.7 KFH46059.1 - 2.4e-08 33.3 0.6 4e-08 32.6 0.4 1.4 1 0 0 1 1 1 1 U1 zinc finger TetR_C_6 PF13977.1 KFH46059.1 - 0.05 13.6 1.7 0.092 12.7 0.4 2.0 2 0 0 2 2 2 0 Bacterial transcriptional repressor SRP-alpha_N PF04086.8 KFH46059.1 - 2.2 7.5 15.4 4.3 6.6 10.4 1.6 1 1 1 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal ERM PF00769.14 KFH46059.1 - 2.8 7.4 14.3 0.13 11.8 5.6 1.7 1 1 1 2 2 2 0 Ezrin/radixin/moesin family bZIP_1 PF00170.16 KFH46060.1 - 5.7e-06 26.1 2.5 1.1e-05 25.2 1.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor Filament PF00038.16 KFH46060.1 - 0.37 10.2 9.0 0.43 10.0 5.7 1.4 1 1 0 1 1 1 0 Intermediate filament protein DDRGK PF09756.4 KFH46060.1 - 8.5 5.7 11.0 19 4.6 7.6 1.5 1 0 0 1 1 1 0 DDRGK domain TAS2R PF05296.8 KFH46061.1 - 0.0044 15.9 0.2 0.005 15.7 0.1 1.1 1 0 0 1 1 1 1 Mammalian taste receptor protein (TAS2R) Peptidase_M36 PF02128.10 KFH46062.1 - 2.7e-149 497.1 1.2 3.6e-149 496.7 0.9 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 KFH46062.1 - 1.4e-08 34.0 4.3 1.4e-08 34.0 3.0 1.8 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.10 KFH46062.1 - 5.8e-06 26.1 0.0 1.8e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Sec3_C PF09763.4 KFH46063.1 - 1.3e-227 757.3 0.0 1.7e-227 756.9 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 KFH46063.1 - 2.7e-28 97.6 0.0 5.1e-28 96.7 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.1 KFH46063.1 - 0.047 13.8 0.2 0.24 11.5 0.0 2.1 2 0 0 2 2 2 0 Sec3 exocyst complex subunit Vps52 PF04129.7 KFH46063.1 - 0.087 11.3 0.8 0.26 9.7 0.1 1.9 2 0 0 2 2 2 0 Vps52 / Sac2 family HEAT_EZ PF13513.1 KFH46064.1 - 2.8e-22 78.5 7.1 1.6e-07 31.5 0.0 9.2 11 0 0 11 11 11 3 HEAT-like repeat HEAT_2 PF13646.1 KFH46064.1 - 1.1e-18 67.2 10.6 0.014 15.6 0.2 7.6 4 3 3 7 7 7 5 HEAT repeats HEAT PF02985.17 KFH46064.1 - 4.7e-18 63.5 3.4 0.00037 20.3 0.0 8.4 8 0 0 8 8 8 4 HEAT repeat Adaptin_N PF01602.15 KFH46064.1 - 2.2e-09 36.1 0.0 0.0025 16.2 0.0 4.3 2 1 1 3 3 3 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 KFH46064.1 - 3.7e-08 33.6 0.0 0.0069 16.7 0.0 4.8 3 1 1 4 4 4 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 KFH46064.1 - 1.7e-07 31.2 0.1 0.069 12.9 0.0 4.7 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 KFH46064.1 - 1.9e-06 27.4 0.0 0.029 13.7 0.0 3.8 3 0 0 3 3 3 1 CLASP N terminal IBN_N PF03810.14 KFH46064.1 - 1.9e-06 27.6 0.3 4.5e-05 23.2 0.1 3.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain Arm PF00514.18 KFH46064.1 - 4.9e-06 26.1 1.1 0.25 11.2 0.0 5.8 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.2 KFH46064.1 - 0.0032 17.3 0.1 4.5 7.3 0.0 3.9 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion DUF2454 PF10521.4 KFH46064.1 - 0.018 14.0 0.0 0.098 11.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2454) V-ATPase_H_N PF03224.9 KFH46064.1 - 0.12 11.5 0.1 46 2.9 0.0 3.8 1 1 0 3 3 3 0 V-ATPase subunit H MMS19_C PF12460.3 KFH46064.1 - 0.32 9.6 3.8 3 6.4 0.1 4.0 5 0 0 5 5 5 0 RNAPII transcription regulator C-terminal Filament PF00038.16 KFH46066.1 - 4.6e-06 26.3 41.6 4.6e-06 26.3 28.8 7.4 1 1 5 6 6 6 3 Intermediate filament protein GAS PF13851.1 KFH46066.1 - 0.0024 17.1 19.5 0.0024 17.1 13.5 8.1 1 1 7 8 8 8 2 Growth-arrest specific micro-tubule binding HrpB7 PF09486.5 KFH46066.1 - 0.007 16.2 14.7 0.007 16.2 10.2 10.2 2 2 9 11 11 11 1 Bacterial type III secretion protein (HrpB7) Bap31 PF05529.7 KFH46066.1 - 0.009 15.4 1.3 0.009 15.4 0.9 12.1 2 1 3 6 6 6 1 B-cell receptor-associated protein 31-like DUF641 PF04859.7 KFH46066.1 - 0.0092 15.7 5.2 0.0092 15.7 3.6 12.0 1 1 10 12 12 12 2 Plant protein of unknown function (DUF641) Reo_sigmaC PF04582.7 KFH46066.1 - 0.02 14.1 86.7 0.017 14.2 2.4 8.5 1 1 4 8 8 8 0 Reovirus sigma C capsid protein Fib_alpha PF08702.5 KFH46066.1 - 2.1 8.4 77.5 0.25 11.4 0.3 9.4 1 1 6 9 9 9 0 Fibrinogen alpha/beta chain family N2227 PF07942.7 KFH46067.1 - 4e-61 206.3 0.0 6.1e-61 205.7 0.0 1.3 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 KFH46067.1 - 2e-05 24.3 0.1 6.8e-05 22.6 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH46067.1 - 0.0015 18.9 0.0 0.026 15.0 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH46067.1 - 0.025 15.0 0.0 0.32 11.5 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain WD40 PF00400.27 KFH46068.1 - 2.2e-53 176.3 16.7 2.8e-09 36.4 0.2 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 KFH46068.1 - 1.1e-12 47.4 0.8 2.9e-12 46.0 0.5 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFH46068.1 - 1.2e-12 47.1 1.5 1.5e-12 46.7 0.1 1.9 2 0 0 2 2 2 1 F-box domain PQQ_2 PF13360.1 KFH46068.1 - 0.0093 15.4 0.4 2.6 7.4 0.0 2.8 3 0 0 3 3 3 2 PQQ-like domain PRANC PF09372.5 KFH46068.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 PRANC domain Fe-ADH PF00465.14 KFH46069.1 - 2.4e-103 345.6 0.0 2.9e-103 345.3 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KFH46069.1 - 4.4e-14 52.3 0.0 1.9e-11 43.7 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 KFH46069.1 - 0.036 13.4 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein Complex1_51K PF01512.12 KFH46070.1 - 2.5e-47 160.3 0.0 3.8e-47 159.7 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 KFH46070.1 - 2.9e-17 61.5 2.3 2.9e-17 61.5 1.6 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 KFH46070.1 - 3e-09 36.6 0.0 1e-08 34.9 0.0 2.0 2 0 0 2 2 2 1 SLBB domain Zn_clus PF00172.13 KFH46071.1 - 7.3e-07 28.9 8.8 1.6e-06 27.9 6.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ycf15 PF10705.4 KFH46071.1 - 0.029 14.3 0.1 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 Chloroplast protein precursor Ycf15 putative Smr PF01713.16 KFH46072.1 - 1.7e-10 40.9 0.1 4.7e-10 39.5 0.1 1.8 1 0 0 1 1 1 1 Smr domain Acetyltransf_1 PF00583.19 KFH46073.1 - 2.1e-06 27.6 0.0 3.5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KFH46073.1 - 1.2e-05 25.3 0.0 2.5e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KFH46073.1 - 2.9e-05 24.1 0.0 4.3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFH46073.1 - 0.0061 16.2 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Herpes_capsid PF06112.6 KFH46073.1 - 3.5 7.6 6.9 12 5.8 5.1 1.6 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein SR-25 PF10500.4 KFH46073.1 - 4.7 6.6 7.4 7 6.0 5.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Abhydrolase_3 PF07859.8 KFH46074.1 - 6.8e-40 136.9 0.3 8.5e-40 136.5 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KFH46074.1 - 7.7e-05 21.5 0.0 0.00014 20.7 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KFH46074.1 - 0.00014 21.6 0.1 0.00022 21.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family HET PF06985.6 KFH46076.1 - 1.4e-24 86.8 0.0 3.9e-24 85.4 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) LUC7 PF03194.10 KFH46077.1 - 1.9e-70 237.2 2.1 2.3e-70 237.0 1.4 1.0 1 0 0 1 1 1 1 LUC7 N_terminus MCPsignal PF00015.16 KFH46077.1 - 0.0065 16.0 0.1 0.0092 15.5 0.0 1.2 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF869 PF05911.6 KFH46077.1 - 0.037 12.2 0.4 0.041 12.1 0.3 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) AAA_13 PF13166.1 KFH46077.1 - 0.056 11.9 0.2 0.076 11.4 0.1 1.2 1 0 0 1 1 1 0 AAA domain zf-C4H2 PF10146.4 KFH46077.1 - 0.11 12.4 0.6 0.17 11.8 0.4 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein DUF1241 PF06840.6 KFH46077.1 - 0.13 11.5 0.1 0.83 8.8 0.0 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1241) Fungal_trans PF04082.13 KFH46079.1 - 5.9e-19 67.9 0.2 8.7e-19 67.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH46079.1 - 2.7e-08 33.5 10.2 5.3e-08 32.6 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_47 PF01532.15 KFH46080.1 - 1.2e-161 538.3 0.0 1.4e-161 538.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 MIP PF00230.15 KFH46082.1 - 1.2e-44 152.4 6.2 3.2e-44 151.0 4.3 1.6 1 1 0 1 1 1 1 Major intrinsic protein Asparaginase_2 PF01112.13 KFH46083.1 - 3.9e-45 153.9 0.4 9.6e-24 83.6 0.0 3.2 2 1 1 3 3 3 3 Asparaginase Sporozoite_P67 PF05642.6 KFH46083.1 - 0.17 9.6 5.7 0.22 9.3 3.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen HECT PF00632.20 KFH46084.1 - 2.1e-78 263.6 0.0 3.1e-78 263.1 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.18 KFH46084.1 - 0.00022 20.9 3.5 2.6 7.9 0.0 6.2 5 1 1 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT PF02985.17 KFH46084.1 - 0.014 15.4 2.3 3.4 8.0 0.1 4.4 4 0 0 4 4 4 0 HEAT repeat RRN3 PF05327.6 KFH46084.1 - 0.015 13.4 10.7 0.034 12.2 7.4 1.6 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Adenylsucc_synt PF00709.16 KFH46085.1 - 1e-141 472.4 0.0 1.2e-141 472.1 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase PaaX_C PF08223.6 KFH46085.1 - 0.022 14.4 0.0 0.093 12.4 0.0 1.9 2 0 0 2 2 2 0 PaaX-like protein C-terminal domain Ubie_methyltran PF01209.13 KFH46086.1 - 3.4e-78 261.9 0.0 4.2e-78 261.6 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 KFH46086.1 - 2e-16 59.9 0.0 2.9e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH46086.1 - 4.3e-14 52.7 0.0 1.4e-13 51.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH46086.1 - 2.1e-11 44.1 0.0 3.4e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH46086.1 - 1.5e-10 41.0 0.0 2.3e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFH46086.1 - 2.4e-10 40.6 0.0 3.9e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFH46086.1 - 8.8e-10 38.6 0.0 2e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH46086.1 - 6.9e-09 36.2 0.0 1.3e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFH46086.1 - 0.047 13.0 0.0 0.21 10.9 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase small domain Methyltransf_8 PF05148.10 KFH46086.1 - 0.057 13.0 0.0 0.2 11.2 0.0 1.9 2 0 0 2 2 2 0 Hypothetical methyltransferase DUF3437 PF11919.3 KFH46087.1 - 1.2e-32 111.4 0.0 3.8e-32 109.8 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.17 KFH46087.1 - 0.0034 17.3 0.2 2.6 8.3 0.0 4.8 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 KFH46087.1 - 0.059 13.8 0.9 63 4.2 0.0 4.7 4 0 0 4 4 4 0 HEAT-like repeat Complex1_30kDa PF00329.14 KFH46088.1 - 1.7e-35 121.3 0.0 2.9e-35 120.5 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit DUF2157 PF09925.4 KFH46089.1 - 0.0015 18.1 1.1 0.49 9.9 0.0 2.6 3 0 0 3 3 3 2 Predicted membrane protein (DUF2157) zf-C3HC PF07967.8 KFH46091.1 - 9.3e-40 135.4 0.1 7.2e-35 119.6 0.2 2.2 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 KFH46091.1 - 2.6e-27 94.5 2.7 7.7e-26 89.7 0.0 2.8 3 0 0 3 3 3 2 Rsm1-like BIR PF00653.16 KFH46091.1 - 1.1e-05 25.7 0.1 0.0018 18.6 0.0 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain DUF3176 PF11374.3 KFH46092.1 - 0.026 14.3 0.0 0.05 13.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) Sugar_tr PF00083.19 KFH46093.1 - 5.3e-77 259.2 23.5 9.6e-77 258.4 16.3 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH46093.1 - 4.6e-42 143.9 43.6 8.7e-32 110.1 15.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFH46093.1 - 0.00039 18.7 1.5 0.00039 18.7 1.0 2.3 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF3154 PF11351.3 KFH46093.1 - 1.1 9.0 4.6 0.83 9.4 0.1 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3154) 2OG-FeII_Oxy_2 PF13532.1 KFH46094.1 - 4.7e-31 108.1 0.0 7.4e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KFH46094.1 - 0.0062 17.0 0.0 0.014 15.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.13 KFH46096.1 - 9.9e-21 73.7 0.2 1.7e-20 72.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF747 PF05346.6 KFH46097.1 - 3.3e-131 437.2 4.3 4.2e-131 436.9 2.9 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family zf-C2H2_2 PF12756.2 KFH46098.1 - 2.4e-35 120.6 7.2 1.1e-29 102.5 0.4 3.4 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KFH46098.1 - 1.4e-09 37.8 14.8 9e-07 28.8 0.9 4.1 4 1 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFH46098.1 - 2.2e-07 30.8 0.5 2.2e-07 30.8 0.3 3.0 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-DBF PF07535.7 KFH46098.1 - 0.0078 15.8 6.7 0.35 10.5 0.3 4.1 4 0 0 4 4 4 1 DBF zinc finger DUF629 PF04780.7 KFH46098.1 - 0.011 14.2 0.0 0.019 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF629) AKAP95 PF04988.7 KFH46098.1 - 0.62 9.8 4.2 8.1 6.1 0.0 2.8 2 1 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2 PF00096.21 KFH46098.1 - 2.4 8.6 18.8 13 6.3 0.2 4.8 4 1 0 4 4 4 0 Zinc finger, C2H2 type A2L_zn_ribbon PF08792.5 KFH46098.1 - 5.4 6.6 6.0 22 4.6 0.2 3.3 3 0 0 3 3 3 0 A2L zinc ribbon domain adh_short PF00106.20 KFH46100.1 - 1.4e-25 90.1 0.9 1.8e-25 89.8 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH46100.1 - 7.3e-14 52.1 0.1 9.7e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KFH46100.1 - 0.0021 18.1 0.2 0.0046 16.9 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding ApbA PF02558.11 KFH46100.1 - 0.0058 16.0 0.1 0.0099 15.3 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA YdfZ PF14001.1 KFH46100.1 - 0.011 15.9 1.3 3.1 8.1 0.0 3.2 4 0 0 4 4 4 0 YdfZ protein TrkA_N PF02254.13 KFH46100.1 - 0.015 15.2 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain DUF1776 PF08643.5 KFH46100.1 - 0.027 13.6 0.0 0.25 10.4 0.0 2.0 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) 2-Hacid_dh_C PF02826.14 KFH46100.1 - 0.032 13.3 0.1 0.092 11.8 0.1 1.7 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NmrA PF05368.8 KFH46100.1 - 0.037 13.2 0.1 0.063 12.5 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family ADH_zinc_N PF00107.21 KFH46100.1 - 0.083 12.4 0.7 0.18 11.3 0.2 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase NAD_binding_2 PF03446.10 KFH46100.1 - 0.1 12.4 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Tim17 PF02466.14 KFH46102.1 - 1.1e-32 112.7 7.4 1.4e-32 112.4 5.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family adh_short_C2 PF13561.1 KFH46104.1 - 2.5e-31 109.2 0.0 3.1e-31 108.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFH46104.1 - 1.1e-29 103.4 0.0 1.6e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH46104.1 - 4.4e-10 39.5 0.0 6.7e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFH46104.1 - 3.1e-05 23.5 0.0 0.00014 21.3 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Melibiase PF02065.13 KFH46105.1 - 6.8e-11 41.4 0.0 3.9e-09 35.6 0.0 2.3 2 0 0 2 2 2 2 Melibiase LysM PF01476.15 KFH46107.1 - 7.2e-13 48.2 0.0 1.3e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 LysM domain DUF3357 PF11837.3 KFH46107.1 - 0.1 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) SKG6 PF08693.5 KFH46109.1 - 0.00045 19.4 0.1 0.0012 18.1 0.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CFEM PF05730.6 KFH46109.1 - 0.00046 19.9 2.7 0.00075 19.2 1.9 1.3 1 0 0 1 1 1 1 CFEM domain Podoplanin PF05808.6 KFH46109.1 - 0.0016 17.9 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 Podoplanin DUF4448 PF14610.1 KFH46109.1 - 0.086 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF4229 PF14012.1 KFH46109.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Peptidase_M20 PF01546.23 KFH46110.1 - 6.8e-22 77.8 0.0 1.2e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 KFH46110.1 - 8.8e-17 60.2 4.3 0.0008 19.1 0.0 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat M20_dimer PF07687.9 KFH46110.1 - 2.4e-06 27.2 0.0 4.4e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Cation_efflux PF01545.16 KFH46110.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Cation efflux family Peptidase_M42 PF05343.9 KFH46110.1 - 0.23 10.2 0.0 0.73 8.5 0.0 1.8 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase Stm1_N PF09598.5 KFH46111.1 - 5.8 7.6 11.2 51 4.6 4.1 3.0 2 0 0 2 2 2 0 Stm1 FAD_binding_3 PF01494.14 KFH46112.1 - 1.2e-27 96.9 0.1 4.8e-27 94.9 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 KFH46112.1 - 1.6e-06 27.4 0.5 0.026 13.6 0.0 3.1 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 KFH46112.1 - 5.3e-05 22.3 0.4 0.071 12.0 0.0 2.9 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.19 KFH46112.1 - 8e-05 21.6 5.2 0.003 16.5 0.4 3.0 2 1 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 KFH46112.1 - 0.00082 17.9 0.2 0.064 11.7 0.1 2.7 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.1 KFH46112.1 - 0.0011 18.9 0.2 0.003 17.5 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KFH46112.1 - 0.0019 18.5 0.4 0.057 13.8 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFH46112.1 - 0.0076 15.3 0.1 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 KFH46112.1 - 0.025 13.4 0.3 0.045 12.5 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 KFH46112.1 - 0.028 14.3 0.1 0.055 13.3 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KFH46112.1 - 0.042 12.4 0.1 0.042 12.4 0.1 1.9 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 KFH46112.1 - 0.077 13.0 1.3 0.36 10.8 0.3 2.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PTPA PF03095.10 KFH46113.1 - 3.2e-109 364.7 0.0 3.8e-109 364.4 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Peptidase_S58 PF03576.9 KFH46115.1 - 4.8e-101 338.1 5.3 2.4e-100 335.8 3.7 1.8 1 1 0 1 1 1 1 Peptidase family S58 Ribosomal_60s PF00428.14 KFH46115.1 - 0.013 15.8 2.1 0.017 15.4 0.5 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Hexapep PF00132.19 KFH46116.1 - 1.8e-07 30.3 9.6 0.0015 17.9 0.5 4.4 3 1 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KFH46116.1 - 0.0044 16.5 13.5 1.2 8.7 0.1 4.0 2 1 2 4 4 4 3 Hexapeptide repeat of succinyl-transferase Peptidase_S9 PF00326.16 KFH46117.1 - 1.8e-05 24.1 0.0 2.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 KFH46117.1 - 3.8e-05 23.0 4.8 0.00082 18.6 0.1 3.2 2 1 0 2 2 2 2 Esterase PHB depolymerase adh_short PF00106.20 KFH46118.1 - 3e-20 72.7 0.4 5.1e-20 72.0 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH46118.1 - 2.3e-09 37.3 0.0 3.1e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH46118.1 - 1.2e-06 28.3 0.0 1.8e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KFH46118.1 - 0.00013 21.2 0.0 0.00019 20.6 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KFH46118.1 - 0.00041 20.3 0.4 0.00086 19.3 0.2 1.5 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_2 PF03446.10 KFH46118.1 - 0.06 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase PEX11 PF05648.9 KFH46119.1 - 2.3e-21 76.0 2.3 2.9e-20 72.5 1.6 2.2 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Phage_Gp23 PF10669.4 KFH46119.1 - 0.22 11.6 1.1 0.45 10.6 0.8 1.5 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) CDC27 PF09507.5 KFH46120.1 - 0.00029 20.1 19.8 0.00043 19.6 13.7 1.3 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 TFIIA PF03153.8 KFH46120.1 - 0.11 12.3 10.8 0.17 11.7 7.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IncA PF04156.9 KFH46120.1 - 1.8 8.1 4.7 2.2 7.8 3.3 1.2 1 0 0 1 1 1 0 IncA protein Hex_IIIa PF02455.11 KFH46120.1 - 3 6.4 8.7 3.9 6.0 6.0 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) MMR1 PF08505.5 KFH46120.1 - 8.4 6.3 11.4 1.8 8.5 4.2 2.1 1 1 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein TRAP-gamma PF07074.7 KFH46121.1 - 0.98 8.9 3.0 0.73 9.3 0.2 2.0 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF4175 PF13779.1 KFH46121.1 - 5.8 4.4 9.5 1 6.9 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) 3HCDH_N PF02737.13 KFH46122.1 - 1.8e-23 83.1 0.0 3.7e-23 82.0 0.0 1.5 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KFH46122.1 - 2.1e-22 79.3 0.0 5.6e-22 77.9 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 KFH46122.1 - 0.00044 19.9 0.0 0.00072 19.3 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 KFH46122.1 - 0.005 16.6 0.0 0.0082 15.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 KFH46122.1 - 0.0082 15.5 0.0 0.029 13.8 0.0 2.0 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Fasciclin PF02469.17 KFH46123.1 - 4.1e-44 149.6 0.0 1.5e-25 89.6 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain Complex1_LYR_1 PF13232.1 KFH46124.1 - 9e-09 35.4 0.2 3e-08 33.7 0.0 2.1 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR PF05347.10 KFH46124.1 - 7.6e-08 32.0 0.1 3.9e-07 29.7 0.0 2.2 2 0 0 2 2 2 1 Complex 1 protein (LYR family) E1_dh PF00676.15 KFH46126.1 - 2.5e-82 276.0 0.0 2.9e-82 275.7 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 KFH46126.1 - 0.00053 19.5 0.0 0.007 15.9 0.0 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 KFH46126.1 - 0.13 11.1 0.0 0.68 8.8 0.0 1.9 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase FGGY_C PF02782.11 KFH46127.1 - 9.5e-73 244.0 1.2 1.5e-72 243.4 0.8 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KFH46127.1 - 1.4e-66 224.3 0.0 1.9e-66 223.8 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 KFH46127.1 - 0.062 12.5 0.3 5.8 6.1 0.0 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Asparaginase_2 PF01112.13 KFH46128.1 - 2.3e-77 259.8 0.0 3e-77 259.4 0.0 1.1 1 0 0 1 1 1 1 Asparaginase DUF2433 PF10360.4 KFH46129.1 - 2e-54 183.4 0.0 4e-54 182.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Zds_C PF08632.5 KFH46129.1 - 1.4e-29 101.2 0.5 2.4e-29 100.4 0.3 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF2360 PF10152.4 KFH46129.1 - 0.0034 17.6 0.8 0.0034 17.6 0.6 5.7 4 1 0 4 4 4 1 Predicted coiled-coil domain-containing protein (DUF2360) Metallophos_2 PF12850.2 KFH46129.1 - 0.014 15.2 0.0 0.031 14.1 0.0 1.6 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KFH46129.1 - 0.02 14.2 0.0 0.038 13.3 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase DAO PF01266.19 KFH46131.1 - 3.8e-49 167.5 0.1 5.2e-49 167.0 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFH46131.1 - 5.3e-08 32.1 1.4 0.002 17.0 0.4 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 KFH46131.1 - 3.2e-06 26.4 1.4 4.1e-05 22.8 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFH46131.1 - 0.0023 17.8 0.0 0.0054 16.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KFH46131.1 - 0.0083 15.8 0.0 0.036 13.7 0.0 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 KFH46131.1 - 0.034 13.0 0.4 0.73 8.6 0.2 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.9 KFH46131.1 - 0.054 11.9 0.1 0.08 11.4 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 KFH46131.1 - 0.11 12.8 0.3 0.38 11.1 0.2 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KFH46131.1 - 0.16 10.8 0.2 0.91 8.3 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_8 PF13450.1 KFH46131.1 - 1.9 8.5 8.1 0.17 11.9 0.1 3.3 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain zf-RING_4 PF14570.1 KFH46132.1 - 3.1e-19 68.2 12.2 6.1e-19 67.3 8.5 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 KFH46132.1 - 4e-08 32.7 0.0 2.2e-07 30.3 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH46132.1 - 4.6e-07 29.7 0.0 1.5e-06 28.0 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 KFH46132.1 - 2.7e-06 26.9 6.6 4.9e-06 26.1 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 KFH46132.1 - 2.7e-05 23.4 2.1 2.7e-05 23.4 1.5 2.9 3 0 0 3 3 2 1 Rtf2 RING-finger RRM_5 PF13893.1 KFH46132.1 - 0.001 18.8 0.0 0.0024 17.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.3 KFH46132.1 - 0.0057 15.9 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated Baculo_IE-1 PF05290.6 KFH46132.1 - 0.075 12.7 5.0 0.13 11.9 3.5 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-UDP PF14569.1 KFH46132.1 - 0.077 12.7 3.1 0.21 11.3 2.1 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4 PF00097.20 KFH46132.1 - 0.083 12.5 10.3 0.22 11.1 7.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Nup35_RRM_2 PF14605.1 KFH46132.1 - 0.1 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif FYVE PF01363.16 KFH46132.1 - 0.16 11.8 4.7 0.38 10.6 3.2 1.5 1 0 0 1 1 1 0 FYVE zinc finger zf-C3HC4_2 PF13923.1 KFH46132.1 - 1 9.4 10.8 1.9 8.5 7.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.11 KFH46132.1 - 2.6 7.9 17.6 0.012 15.5 2.6 2.4 1 1 1 2 2 2 0 FYVE-type zinc finger Prok-RING_4 PF14447.1 KFH46132.1 - 5.5 6.6 9.7 1.4 8.5 3.3 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 A_deaminase PF00962.17 KFH46134.1 - 2.6e-43 148.2 0.0 3.8e-42 144.4 0.0 2.1 1 1 0 1 1 1 1 Adenosine/AMP deaminase Ion_trans_2 PF07885.11 KFH46135.1 - 2.2e-34 116.9 25.6 3.2e-19 68.3 3.3 2.8 3 0 0 3 3 3 2 Ion channel DUF1513 PF07433.6 KFH46135.1 - 0.029 13.2 0.0 0.045 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) Ion_trans PF00520.26 KFH46135.1 - 0.044 13.0 13.1 0.028 13.6 1.6 2.7 2 1 0 2 2 2 0 Ion transport protein SieB PF14163.1 KFH46135.1 - 0.089 12.3 2.9 1.8 8.1 0.0 3.1 3 1 1 4 4 4 0 Superinfection exclusion protein B SRP40_C PF05022.7 KFH46136.1 - 5.7e-21 74.8 0.6 5.7e-21 74.8 0.4 2.3 2 0 0 2 2 2 1 SRP40, C-terminal domain MMR_HSR1 PF01926.18 KFH46138.1 - 2.6e-17 62.8 0.0 4.2e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KFH46138.1 - 1.8e-09 37.6 0.0 0.0022 17.8 0.0 2.3 1 1 0 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 KFH46138.1 - 3e-06 26.7 0.0 4.8e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 KFH46138.1 - 0.016 14.7 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Septin PF00735.13 KFH46138.1 - 0.027 13.5 0.0 0.05 12.6 0.0 1.4 1 1 0 1 1 1 0 Septin Miro PF08477.8 KFH46138.1 - 0.043 14.3 0.0 0.078 13.4 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein AAA_33 PF13671.1 KFH46138.1 - 0.043 13.7 0.0 0.11 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 KFH46138.1 - 0.051 12.7 0.3 0.2 10.8 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AIG1 PF04548.11 KFH46138.1 - 0.058 12.5 0.0 0.13 11.3 0.0 1.6 1 1 0 1 1 1 0 AIG1 family FeoB_N PF02421.13 KFH46138.1 - 0.092 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B CNH PF00780.17 KFH46139.1 - 3.7e-75 252.8 0.0 1.1e-74 251.3 0.0 1.7 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 KFH46139.1 - 8.2e-42 142.3 0.0 2e-41 141.0 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 KFH46139.1 - 2.5e-34 118.7 0.0 4.4e-34 117.9 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 KFH46139.1 - 5.1e-15 54.9 0.1 9.6e-15 54.0 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ADH_zinc_N PF00107.21 KFH46142.1 - 2.2e-11 43.4 0.0 4.5e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFH46142.1 - 0.063 13.0 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 KFH46143.1 - 8.3e-17 61.5 0.0 2.2e-15 56.9 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH46143.1 - 0.00021 21.1 0.0 0.0057 16.4 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH46143.1 - 0.0038 16.9 0.0 0.027 14.1 0.0 2.0 2 0 0 2 2 2 1 KR domain Ank PF00023.25 KFH46143.1 - 0.027 14.2 0.0 9.9 6.1 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat eIF-5a PF01287.15 KFH46144.1 - 4.5e-07 29.7 0.1 1.2e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold NmrA PF05368.8 KFH46145.1 - 1.3e-25 90.0 0.0 1.7e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFH46145.1 - 1.2e-10 41.6 0.5 3.3e-10 40.2 0.2 2.0 2 1 0 2 2 2 1 NADH(P)-binding DapB_N PF01113.15 KFH46145.1 - 0.1 12.5 0.1 0.52 10.2 0.0 2.2 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Fungal_trans PF04082.13 KFH46146.1 - 1.7e-11 43.5 0.1 3e-11 42.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH46146.1 - 0.00079 19.2 2.3 0.00079 19.2 1.6 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_2_N PF02837.13 KFH46147.1 - 2.6e-05 23.8 0.0 4.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain GATase_7 PF13537.1 KFH46148.1 - 1.4e-12 47.4 0.0 2.3e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 KFH46148.1 - 6.5e-11 42.0 0.2 2.6e-10 40.1 0.1 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain GATase_6 PF13522.1 KFH46148.1 - 8.2e-10 38.7 0.0 1.7e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 KFH46148.1 - 3.6e-09 35.8 0.0 5.7e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II NAD_binding_10 PF13460.1 KFH46149.1 - 1.1e-11 45.0 0.0 1.6e-11 44.5 0.0 1.3 1 1 0 1 1 1 1 NADH(P)-binding Auxin_inducible PF02519.9 KFH46149.1 - 0.0093 16.0 0.0 0.13 12.3 0.0 2.2 2 0 0 2 2 2 1 Auxin responsive protein Glyco_hydro_81 PF03639.8 KFH46150.1 - 1.6e-191 637.9 10.7 1.9e-191 637.7 7.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Glyco_hydro_2_C PF02836.12 KFH46151.1 - 6.2e-98 327.3 0.4 8.6e-98 326.9 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 KFH46151.1 - 2.5e-60 203.8 0.0 4.4e-60 203.0 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 KFH46151.1 - 2e-53 180.3 0.4 3.2e-53 179.6 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KFH46151.1 - 8.4e-06 26.1 0.1 5.9e-05 23.4 0.0 2.6 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Exo_endo_phos PF03372.18 KFH46152.1 - 4.2e-16 59.6 3.6 1.6e-15 57.7 2.5 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Acetyltransf_1 PF00583.19 KFH46154.1 - 1.8e-12 47.1 0.3 8.9e-12 44.8 0.1 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFH46154.1 - 1.6e-05 25.0 0.0 2.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFH46154.1 - 4.8e-05 23.4 0.1 6.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KFH46154.1 - 0.00029 21.0 0.0 0.00051 20.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KFH46154.1 - 0.002 18.0 0.0 0.0025 17.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 KFH46156.1 - 1.1e-13 50.6 24.2 5.2e-09 35.2 2.1 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily DIM PF08194.7 KFH46157.1 - 0.063 13.2 0.1 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 DIM protein CBM_19 PF03427.8 KFH46157.1 - 0.37 10.5 8.3 0.67 9.7 5.8 1.5 1 1 0 1 1 1 0 Carbohydrate binding domain (family 19) RabGAP-TBC PF00566.13 KFH46158.1 - 3.6e-47 160.6 0.0 7.1e-47 159.6 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.1 KFH46158.1 - 1.5e-07 30.7 0.5 0.057 13.3 0.2 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 KFH46158.1 - 5.1e-06 26.5 0.1 6.4e-05 23.0 0.2 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KFH46158.1 - 1.2e-05 24.2 0.2 0.11 11.8 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 KFH46158.1 - 0.002 17.3 0.7 0.5 9.7 0.3 3.1 2 0 0 2 2 2 1 EF hand GRAM PF02893.15 KFH46158.1 - 0.031 13.7 0.0 0.072 12.6 0.0 1.7 1 0 0 1 1 1 0 GRAM domain Ribosomal_L7Ae PF01248.21 KFH46159.1 - 4e-22 77.5 0.2 1.9e-21 75.3 0.1 2.1 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Cytadhesin_P30 PF07271.6 KFH46159.1 - 0.036 13.3 0.9 0.046 13.0 0.6 1.3 1 0 0 1 1 1 0 Cytadhesin P30/P32 Ycf1 PF05758.7 KFH46159.1 - 0.42 8.2 3.5 0.38 8.4 2.5 1.2 1 0 0 1 1 1 0 Ycf1 Spore_coat_CotO PF14153.1 KFH46159.1 - 7.9 5.8 14.1 1.6 8.1 7.5 1.5 2 0 0 2 2 2 0 Spore coat protein CotO NPR3 PF03666.8 KFH46159.1 - 9.1 4.6 8.0 14 4.0 5.5 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.9 KFH46160.1 - 2.8 5.8 7.1 4.1 5.3 4.9 1.1 1 0 0 1 1 1 0 CDC45-like protein NIF PF03031.13 KFH46161.1 - 3.4e-40 137.3 0.0 5.2e-40 136.7 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ABC2_membrane PF01061.19 KFH46163.1 - 1.7e-86 288.7 54.3 3.3e-45 153.8 13.2 2.9 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 KFH46163.1 - 6.6e-34 117.1 3.1 1.9e-16 60.6 0.0 2.9 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 KFH46163.1 - 1.7e-29 101.4 6.5 6.8e-24 83.5 0.0 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 KFH46163.1 - 3.3e-07 30.2 0.0 8.6e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal cobW PF02492.14 KFH46163.1 - 2.2e-06 27.2 0.2 0.00084 18.8 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KFH46163.1 - 2.9e-06 27.2 0.1 0.0012 18.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KFH46163.1 - 5.7e-06 26.4 0.1 0.023 14.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 KFH46163.1 - 9.8e-06 24.8 0.6 0.00044 19.4 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KFH46163.1 - 1.4e-05 24.6 0.0 0.07 12.5 0.0 3.3 3 1 0 3 3 3 2 AAA domain AAA_22 PF13401.1 KFH46163.1 - 4.4e-05 23.6 0.1 0.11 12.6 0.0 3.4 4 1 0 4 4 2 1 AAA domain AAA_29 PF13555.1 KFH46163.1 - 6.9e-05 22.2 2.7 0.15 11.6 0.1 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KFH46163.1 - 0.00058 19.7 0.0 0.37 10.7 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 KFH46163.1 - 0.00075 19.0 0.0 0.47 9.8 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_28 PF13521.1 KFH46163.1 - 0.0011 18.9 0.4 0.0027 17.6 0.1 1.8 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 KFH46163.1 - 0.0018 18.2 1.0 0.1 12.5 0.3 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KFH46163.1 - 0.0021 18.8 0.0 0.042 14.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 KFH46163.1 - 0.0027 17.3 0.6 0.052 13.1 0.2 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 SMC_N PF02463.14 KFH46163.1 - 0.0057 15.9 3.7 0.12 11.6 0.0 3.6 4 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 KFH46163.1 - 0.0062 16.8 0.0 0.1 12.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KFH46163.1 - 0.012 15.3 0.2 0.31 10.6 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_10 PF12846.2 KFH46163.1 - 0.014 14.8 0.1 2.7 7.3 0.1 2.7 3 0 0 3 3 2 0 AAA-like domain AAA_15 PF13175.1 KFH46163.1 - 0.016 14.2 0.0 1.4 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.17 KFH46163.1 - 0.019 13.8 0.3 2.5 6.8 0.1 2.5 3 0 0 3 3 2 0 NB-ARC domain Miro PF08477.8 KFH46163.1 - 0.029 14.8 0.1 1.2 9.6 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_24 PF13479.1 KFH46163.1 - 0.034 13.7 0.4 0.34 10.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 KFH46163.1 - 0.041 12.8 0.1 0.29 10.1 0.1 2.2 2 0 0 2 2 2 0 Septin Arch_ATPase PF01637.13 KFH46163.1 - 0.058 13.0 0.0 20 4.8 0.0 3.0 3 0 0 3 3 3 0 Archaeal ATPase GBP PF02263.14 KFH46163.1 - 0.061 12.3 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain AAA PF00004.24 KFH46163.1 - 0.073 13.2 0.7 9.8 6.3 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 KFH46163.1 - 0.15 11.7 0.1 0.37 10.4 0.1 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase Dynamin_N PF00350.18 KFH46163.1 - 0.17 11.7 2.5 1.6 8.5 0.0 3.0 4 0 0 4 4 2 0 Dynamin family AAA_19 PF13245.1 KFH46163.1 - 0.17 11.6 1.3 13 5.6 0.2 3.0 3 0 0 3 3 3 0 Part of AAA domain PduV-EutP PF10662.4 KFH46163.1 - 0.19 11.1 0.6 0.46 9.9 0.2 1.7 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation ABC2_membrane_3 PF12698.2 KFH46163.1 - 7.2 5.5 52.6 0.008 15.2 9.6 3.7 4 0 0 4 4 4 0 ABC-2 family transporter protein DUF605 PF04652.11 KFH46164.1 - 6.4 6.0 18.0 8.4 5.6 12.5 1.2 1 0 0 1 1 1 0 Vta1 like Nse4_C PF08743.5 KFH46166.1 - 3.9e-30 103.7 0.0 8.3e-30 102.6 0.0 1.6 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 KFH46166.1 - 3.6e-19 68.3 0.2 1.6e-18 66.2 0.1 2.2 1 1 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE HAUS-augmin3 PF14932.1 KFH46166.1 - 0.053 12.6 0.2 2.5 7.2 0.0 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DinB_2 PF12867.2 KFH46166.1 - 0.076 13.3 1.5 9.4 6.5 0.0 2.6 3 0 0 3 3 3 0 DinB superfamily DUF3326 PF11805.3 KFH46166.1 - 0.18 10.4 0.0 0.28 9.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3326) Nucleo_P87 PF07267.6 KFH46166.1 - 6.1 5.3 10.5 1.8 7.1 1.7 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 HET PF06985.6 KFH46167.1 - 4.2e-23 82.0 0.0 8.9e-23 80.9 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PQQ_2 PF13360.1 KFH46167.1 - 0.035 13.5 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 PQQ-like domain DUF3703 PF12487.3 KFH46167.1 - 0.17 11.5 0.0 0.38 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3703) UcrQ PF02939.11 KFH46168.1 - 2.5e-28 97.6 0.3 3.2e-28 97.3 0.2 1.1 1 0 0 1 1 1 1 UcrQ family Pkinase PF00069.20 KFH46169.1 - 3.2e-12 46.1 0.0 3.9e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH46169.1 - 3.7e-06 26.2 0.0 4.6e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase CST-I PF06002.7 KFH46169.1 - 0.039 13.2 0.2 0.049 12.9 0.1 1.1 1 0 0 1 1 1 0 Alpha-2,3-sialyltransferase (CST-I) Yae1_N PF09811.4 KFH46170.1 - 8.1e-10 38.0 5.9 1.3e-09 37.4 4.1 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal AAA_17 PF13207.1 KFH46171.1 - 2.3e-11 44.5 0.7 6.1e-11 43.2 0.4 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFH46171.1 - 4.4e-08 33.5 0.1 1.3e-07 31.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 KFH46171.1 - 1.2e-05 24.9 0.0 1.5e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 KFH46171.1 - 4.9e-05 23.2 0.1 0.00013 21.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KFH46171.1 - 7.2e-05 22.9 0.0 0.00016 21.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KFH46171.1 - 9.8e-05 21.3 0.0 0.00052 18.9 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain AAA_19 PF13245.1 KFH46171.1 - 0.00013 21.6 0.3 0.00068 19.3 0.0 2.3 3 0 0 3 3 3 1 Part of AAA domain Zeta_toxin PF06414.7 KFH46171.1 - 0.00016 20.8 0.2 0.00039 19.5 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.1 KFH46171.1 - 0.00019 21.5 0.0 0.00052 20.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain SKI PF01202.17 KFH46171.1 - 0.00078 19.3 0.0 0.13 12.1 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase Thymidylate_kin PF02223.12 KFH46171.1 - 0.00082 18.7 0.1 0.0075 15.6 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase AAA_16 PF13191.1 KFH46171.1 - 0.0014 18.6 0.2 0.0024 17.8 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.10 KFH46171.1 - 0.0025 17.5 0.0 0.005 16.5 0.0 1.5 1 0 0 1 1 1 1 NTPase ArgK PF03308.11 KFH46171.1 - 0.0028 16.4 0.0 0.0041 15.9 0.0 1.3 1 0 0 1 1 1 1 ArgK protein ABC_tran PF00005.22 KFH46171.1 - 0.0038 17.5 0.0 0.0054 17.0 0.0 1.5 1 1 0 1 1 1 1 ABC transporter KTI12 PF08433.5 KFH46171.1 - 0.0045 16.2 0.0 0.0072 15.5 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_30 PF13604.1 KFH46171.1 - 0.0047 16.5 0.0 0.0087 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFH46171.1 - 0.0081 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.7 KFH46171.1 - 0.011 15.3 0.1 0.021 14.4 0.0 1.7 1 1 0 1 1 1 0 NACHT domain RuvB_N PF05496.7 KFH46171.1 - 0.016 14.2 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus APS_kinase PF01583.15 KFH46171.1 - 0.02 14.5 0.1 0.053 13.1 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase cobW PF02492.14 KFH46171.1 - 0.026 13.9 0.0 0.052 12.9 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 KFH46171.1 - 0.03 14.2 0.0 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 KFH46171.1 - 0.03 13.8 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATP_bind_1 PF03029.12 KFH46171.1 - 0.036 13.5 0.0 0.052 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein T2SE PF00437.15 KFH46171.1 - 0.037 12.9 0.0 0.065 12.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein MobB PF03205.9 KFH46171.1 - 0.039 13.6 0.0 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 KFH46171.1 - 0.044 13.7 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KFH46171.1 - 0.066 12.7 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cytidylate_kin2 PF13189.1 KFH46171.1 - 0.11 12.3 1.3 0.21 11.4 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_10 PF12846.2 KFH46171.1 - 0.12 11.8 0.0 0.3 10.4 0.0 1.6 1 1 0 2 2 2 0 AAA-like domain DUF2075 PF09848.4 KFH46171.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MMR_HSR1 PF01926.18 KFH46171.1 - 0.15 12.0 0.0 0.36 10.7 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.1 KFH46171.1 - 0.24 10.7 1.9 0.45 9.8 0.2 1.9 2 1 0 2 2 2 0 AAA domain DUF4336 PF14234.1 KFH46172.1 - 1.9e-14 53.5 0.0 1.5e-10 40.7 0.0 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF4336) PRELI PF04707.9 KFH46173.1 - 9.4e-18 64.2 0.0 6.7e-16 58.2 0.0 2.1 2 0 0 2 2 2 2 PRELI-like family DUF2505 PF10698.4 KFH46173.1 - 0.092 12.2 0.1 0.41 10.1 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2505) IF-2B PF01008.12 KFH46174.1 - 5.3e-41 140.4 0.3 7.2e-40 136.7 0.2 2.0 1 1 0 1 1 1 1 Initiation factor 2 subunit family Globin PF00042.17 KFH46174.1 - 0.028 14.7 0.1 1.3 9.3 0.0 2.5 2 0 0 2 2 2 0 Globin CAP_N PF01213.14 KFH46176.1 - 0.14 11.4 2.7 0.27 10.5 1.9 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RNase_T PF00929.19 KFH46177.1 - 3.8e-08 33.7 0.0 0.0034 17.6 0.0 2.6 3 0 0 3 3 3 2 Exonuclease DUF3441 PF11923.3 KFH46178.1 - 1.6e-39 133.9 0.2 1.6e-39 133.9 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3441) FbpA PF05833.6 KFH46178.1 - 3.8e-34 118.0 11.3 3.8e-34 118.0 7.8 2.3 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 KFH46178.1 - 8.8e-23 80.0 0.0 2.1e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF814) RNA_pol_Rpb1_5 PF04998.12 KFH46178.1 - 1.3 8.2 6.8 2.2 7.4 3.4 2.2 2 1 0 2 2 2 0 RNA polymerase Rpb1, domain 5 ATP-synt_C PF00137.16 KFH46179.1 - 3.1e-27 94.2 32.7 1e-16 60.5 7.0 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF4199 PF13858.1 KFH46179.1 - 1.3 8.9 9.4 1.5 8.7 0.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) AhpC-TSA PF00578.16 KFH46180.1 - 8e-26 90.1 0.0 1.2e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KFH46180.1 - 4.2e-16 58.8 0.0 6.1e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 KFH46180.1 - 0.0077 16.1 0.0 0.13 12.2 0.0 2.3 1 1 1 2 2 2 1 AhpC/TSA antioxidant enzyme PI3Ka PF00613.15 KFH46181.1 - 7.3e-58 194.7 0.3 1.3e-57 194.0 0.2 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 KFH46181.1 - 1.4e-42 145.8 0.1 1.8e-41 142.1 0.1 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 KFH46181.1 - 3.9e-29 101.2 0.0 6.3e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 C2 PF00168.25 KFH46181.1 - 0.0048 16.7 0.0 0.021 14.6 0.0 2.1 2 0 0 2 2 2 1 C2 domain Peptidase_C1_2 PF03051.10 KFH46182.1 - 1.1e-144 482.2 0.0 1.3e-144 482.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 KFH46182.1 - 3e-06 27.2 0.1 0.011 15.5 0.1 2.3 2 0 0 2 2 2 2 Papain family cysteine protease DUF3292 PF11696.3 KFH46183.1 - 0.19 9.5 1.9 0.25 9.1 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) adh_short_C2 PF13561.1 KFH46184.1 - 3e-27 95.9 0.0 3.8e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFH46184.1 - 3.9e-24 85.4 0.6 5.4e-24 84.9 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH46184.1 - 2.3e-13 50.1 0.2 3.4e-13 49.6 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFH46184.1 - 0.0077 15.6 0.2 0.017 14.5 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 KFH46184.1 - 0.024 14.2 0.0 0.13 11.9 0.1 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 KFH46184.1 - 0.098 12.2 0.4 0.35 10.4 0.1 2.0 2 0 0 2 2 2 0 Zinc-binding dehydrogenase bZIP_1 PF00170.16 KFH46185.1 - 0.028 14.3 4.9 0.059 13.3 3.4 1.4 1 0 0 1 1 1 0 bZIP transcription factor DUF1470 PF07336.6 KFH46185.1 - 0.049 13.9 4.8 0.12 12.6 3.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1470) DUF4387 PF14330.1 KFH46186.1 - 6.7e-30 103.3 0.0 1.6e-29 102.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) DUF1446 PF07287.6 KFH46186.1 - 1e-14 53.8 0.0 2.7e-14 52.4 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1446) Beta-lactamase PF00144.19 KFH46187.1 - 4.7e-35 121.1 0.0 7e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Lipase_GDSL PF00657.17 KFH46188.1 - 1.1e-17 64.6 0.0 1.5e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KFH46188.1 - 8.3e-06 26.0 0.2 2.2e-05 24.6 0.2 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Chitin_synth_1 PF01644.12 KFH46189.1 - 3e-81 271.0 0.3 1.9e-80 268.3 0.1 2.0 2 0 0 2 2 2 1 Chitin synthase Chitin_synth_1N PF08407.6 KFH46189.1 - 7.1e-32 108.9 0.0 1.3e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KFH46189.1 - 3.7e-23 81.7 0.1 3.3e-17 62.0 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KFH46189.1 - 6.2e-09 35.8 4.5 6.2e-09 35.8 3.1 2.6 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KFH46189.1 - 3.2e-07 30.3 0.0 2.3e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Pkinase PF00069.20 KFH46192.1 - 1.7e-38 132.2 0.0 2.1e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH46192.1 - 9.7e-14 51.0 0.0 1.3e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFH46192.1 - 1.9e-05 24.5 0.1 0.0019 17.9 0.0 2.4 2 1 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFH46192.1 - 0.059 12.1 0.1 0.09 11.5 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase AATase PF07247.7 KFH46193.1 - 7e-20 71.0 0.0 5.3e-19 68.1 0.0 2.2 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 KFH46193.1 - 9.7e-05 21.3 0.7 0.00055 18.8 0.0 1.9 2 0 0 2 2 2 1 Condensation domain FAD_binding_3 PF01494.14 KFH46194.1 - 1.6e-22 80.0 1.5 7.8e-19 67.9 0.0 2.1 1 1 1 2 2 2 2 FAD binding domain DAO PF01266.19 KFH46194.1 - 3e-12 46.1 1.5 8.3e-07 28.2 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KFH46194.1 - 4.1e-09 36.8 0.0 6.5e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFH46194.1 - 7.2e-06 25.1 1.5 9.7e-06 24.6 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 KFH46194.1 - 8.2e-06 26.1 1.2 0.058 13.7 1.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KFH46194.1 - 1.1e-05 24.3 3.0 0.00019 20.2 0.0 2.1 1 1 1 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.9 KFH46194.1 - 1.3e-05 23.8 1.3 0.0054 15.2 0.5 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 KFH46194.1 - 2.6e-05 24.2 0.4 7.8e-05 22.6 0.3 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFH46194.1 - 9.9e-05 21.4 0.4 0.00049 19.1 0.3 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 KFH46194.1 - 0.00036 19.5 0.9 0.0012 17.8 0.6 1.7 1 1 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 KFH46194.1 - 0.00086 19.2 4.0 0.0014 18.6 1.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KFH46194.1 - 0.001 18.2 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 KFH46194.1 - 0.0021 17.2 0.5 0.0032 16.5 0.3 1.3 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.19 KFH46194.1 - 0.0084 15.2 1.1 0.14 11.1 0.1 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase SE PF08491.5 KFH46194.1 - 0.015 14.0 0.0 0.22 10.3 0.0 2.3 2 1 1 3 3 3 0 Squalene epoxidase AlaDh_PNT_C PF01262.16 KFH46194.1 - 0.023 14.2 0.2 0.13 11.7 0.1 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 KFH46194.1 - 0.14 11.9 1.8 0.69 9.6 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding NmrA PF05368.8 KFH46197.1 - 2.3e-41 141.5 0.0 2.9e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFH46197.1 - 9.7e-13 48.5 0.0 1.7e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KFH46197.1 - 0.016 13.9 0.1 0.04 12.6 0.1 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KFH46197.1 - 0.063 12.6 0.1 0.13 11.6 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DXP_reductoisom PF02670.11 KFH46197.1 - 0.086 13.3 0.1 0.22 12.0 0.0 1.8 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Pal1 PF08316.6 KFH46198.1 - 6.9e-46 156.1 1.7 6.4e-45 153.0 1.1 2.4 1 1 0 1 1 1 1 Pal1 cell morphology protein Fungal_trans PF04082.13 KFH46199.1 - 3.4e-18 65.4 0.0 5.9e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH46199.1 - 1.2e-08 34.7 10.6 2.3e-08 33.8 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 KFH46200.1 - 7.7e-95 318.0 29.3 9.2e-95 317.8 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH46200.1 - 2.5e-36 125.1 61.9 1e-26 93.4 27.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1761 PF08570.5 KFH46202.1 - 1.8e-24 86.1 1.1 2e-24 85.9 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) Hexapep PF00132.19 KFH46203.1 - 2.7e-09 36.1 3.1 7.5e-05 22.0 0.6 4.3 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KFH46203.1 - 8.9e-08 31.5 0.3 0.00013 21.4 0.2 3.5 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase DUF3455 PF11937.3 KFH46205.1 - 3.6e-22 79.1 0.0 5.8e-22 78.4 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3455) Acetyltransf_1 PF00583.19 KFH46206.1 - 3.7e-14 52.5 0.0 6.7e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KFH46206.1 - 7.6e-07 28.7 0.1 1.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KFH46206.1 - 0.0002 21.4 0.1 0.0027 17.8 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KFH46206.1 - 0.0014 18.7 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFH46206.1 - 0.019 14.8 0.1 0.035 13.9 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TATR PF03430.8 KFH46208.1 - 3.3 6.2 5.2 4.8 5.7 3.6 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator PRELI PF04707.9 KFH46209.1 - 7.5e-41 139.3 0.2 9e-41 139.0 0.1 1.1 1 0 0 1 1 1 1 PRELI-like family GATase_3 PF07685.9 KFH46209.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Band_7 PF01145.20 KFH46210.1 - 5.5e-25 88.3 4.6 5.5e-25 88.3 3.2 1.8 1 1 1 2 2 2 1 SPFH domain / Band 7 family YdfA_immunity PF12127.3 KFH46210.1 - 0.014 14.2 5.3 0.02 13.8 3.7 1.2 1 0 0 1 1 1 0 SigmaW regulon antibacterial DUF2884 PF11101.3 KFH46210.1 - 0.02 14.3 1.4 0.031 13.6 0.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) LMWPc PF01451.16 KFH46211.1 - 3.9e-35 121.1 0.0 4.4e-35 121.0 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Sugar_tr PF00083.19 KFH46212.1 - 1.4e-55 188.7 20.7 1.6e-55 188.4 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH46212.1 - 3.9e-20 71.8 37.2 1.9e-17 63.0 19.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3380 PF11860.3 KFH46212.1 - 0.21 11.6 0.3 0.33 10.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3380) Peptidase_M24 PF00557.19 KFH46213.1 - 1.7e-46 158.4 0.1 2.2e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Med3 PF11593.3 KFH46213.1 - 0.077 12.2 0.2 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal YL1 PF05764.8 KFH46213.1 - 0.23 11.0 8.4 0.36 10.3 5.8 1.3 1 0 0 1 1 1 0 YL1 nuclear protein DUF676 PF05057.9 KFH46215.1 - 9.3e-52 175.4 0.0 1.4e-51 174.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KFH46215.1 - 2.1e-05 24.5 0.0 8.2e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH46215.1 - 3.5e-05 23.5 0.0 8.2e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KFH46215.1 - 0.00034 20.2 0.0 0.00094 18.8 0.0 1.7 1 1 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 KFH46215.1 - 0.033 13.8 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF4611 PF15387.1 KFH46215.1 - 0.13 12.3 0.4 0.24 11.5 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Annexin PF00191.15 KFH46216.1 - 2.3e-20 72.2 0.4 3.8e-05 23.5 0.0 4.6 4 0 0 4 4 4 4 Annexin AhpC-TSA_2 PF13911.1 KFH46217.1 - 1.4e-16 60.4 0.0 3.9e-16 59.0 0.0 1.7 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 KFH46217.1 - 5.7e-06 26.0 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KFH46217.1 - 0.0014 18.1 0.0 0.0029 17.1 0.0 1.5 1 0 0 1 1 1 1 Redoxin Dicty_REP PF05086.7 KFH46217.1 - 3.5 5.2 5.2 4.4 4.9 3.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.12 KFH46217.1 - 3.7 7.3 31.2 5.9 6.6 21.6 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Tir_receptor_C PF07489.6 KFH46217.1 - 8.8 6.0 14.4 1.3 8.7 7.4 1.5 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus MFS_1 PF07690.11 KFH46218.1 - 9e-38 129.8 31.6 9e-38 129.8 21.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KFH46218.1 - 0.0046 16.7 1.6 0.0046 16.7 1.1 2.1 2 0 0 2 2 2 1 MFS_1 like family UNC-93 PF05978.11 KFH46218.1 - 0.0051 16.3 1.4 0.012 15.1 0.9 1.6 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 NAP PF00956.13 KFH46219.1 - 6.1e-87 290.7 11.2 6.1e-87 290.7 7.8 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Ras PF00071.17 KFH46220.1 - 6.1e-46 155.7 0.1 7e-46 155.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFH46220.1 - 7.2e-16 58.7 0.1 9.7e-16 58.3 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFH46220.1 - 9e-08 31.5 0.0 1.1e-07 31.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFH46220.1 - 1.2e-05 24.8 0.0 7e-05 22.3 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFH46220.1 - 3.3e-05 23.8 0.0 5.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KFH46220.1 - 0.005 16.0 0.0 0.012 14.8 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 KFH46220.1 - 0.0079 16.1 0.0 0.0092 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.13 KFH46220.1 - 0.033 13.4 0.0 0.48 9.6 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B adh_short_C2 PF13561.1 KFH46221.1 - 2.2e-17 63.6 0.0 2.5e-17 63.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFH46221.1 - 4.1e-15 56.0 0.7 5.2e-15 55.7 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH46221.1 - 0.0016 18.1 0.1 0.0024 17.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Tropomyosin_1 PF12718.2 KFH46222.1 - 8.3e-47 158.6 39.9 1.1e-46 158.2 27.6 1.2 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 KFH46222.1 - 2.9e-07 29.8 36.5 1.4e-05 24.3 13.3 2.9 1 1 2 3 3 3 3 Tropomyosin Myosin_tail_1 PF01576.14 KFH46222.1 - 3.3e-06 25.1 36.2 3.7e-06 24.9 25.1 1.0 1 0 0 1 1 1 1 Myosin tail ATG16 PF08614.6 KFH46222.1 - 3.5e-05 23.7 33.4 0.00064 19.6 8.0 2.3 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 KFH46222.1 - 0.0019 18.0 7.6 0.0019 18.0 5.3 2.7 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4200 PF13863.1 KFH46222.1 - 0.0031 17.4 38.5 0.23 11.4 13.2 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4200) GAS PF13851.1 KFH46222.1 - 0.0053 15.9 35.4 0.051 12.7 15.1 2.4 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding DivIC PF04977.10 KFH46222.1 - 0.0059 16.0 3.6 0.0059 16.0 2.5 4.2 2 1 2 4 4 4 2 Septum formation initiator bZIP_1 PF00170.16 KFH46222.1 - 0.0067 16.3 37.3 0.0095 15.8 1.6 5.1 1 1 3 4 4 4 1 bZIP transcription factor Mod_r PF07200.8 KFH46222.1 - 0.011 15.6 30.9 0.07 13.0 12.6 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein FlaC_arch PF05377.6 KFH46222.1 - 0.014 15.3 22.6 0.17 11.7 1.3 4.3 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF4201 PF13870.1 KFH46222.1 - 0.014 14.8 29.0 0.22 10.9 7.0 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4201) DUF3450 PF11932.3 KFH46222.1 - 0.017 14.3 28.0 0.13 11.5 7.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) IncA PF04156.9 KFH46222.1 - 0.017 14.6 38.2 0.41 10.2 16.6 2.4 1 1 1 2 2 2 0 IncA protein APG6 PF04111.7 KFH46222.1 - 0.03 13.3 38.6 0.18 10.8 13.6 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 ERM PF00769.14 KFH46222.1 - 0.033 13.7 40.9 0.021 14.3 13.5 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family HALZ PF02183.13 KFH46222.1 - 0.036 13.7 0.7 0.036 13.7 0.5 5.0 4 3 1 5 5 5 0 Homeobox associated leucine zipper ADIP PF11559.3 KFH46222.1 - 0.056 13.3 36.2 0.078 12.8 8.0 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Syntaxin-6_N PF09177.6 KFH46222.1 - 0.067 13.6 20.9 0.44 10.9 3.7 2.9 1 1 2 3 3 3 0 Syntaxin 6, N-terminal EzrA PF06160.7 KFH46222.1 - 0.13 10.3 26.6 0.15 10.1 4.1 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF4140 PF13600.1 KFH46222.1 - 0.14 12.6 25.0 0.68 10.4 3.6 3.1 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) BLOC1_2 PF10046.4 KFH46222.1 - 0.16 12.1 24.1 0.5 10.5 0.7 3.7 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.7 KFH46222.1 - 0.2 11.4 20.0 0.017 14.9 4.1 2.1 1 1 1 2 2 2 0 Laminin Domain II bZIP_2 PF07716.10 KFH46222.1 - 0.2 11.4 42.1 0.27 11.0 0.5 5.6 3 1 3 6 6 5 0 Basic region leucine zipper Spc7 PF08317.6 KFH46222.1 - 0.22 10.1 31.6 0.0062 15.2 12.8 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF972 PF06156.8 KFH46222.1 - 0.24 11.7 28.9 1.1 9.6 1.4 3.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) AP_endonuc_2 PF01261.19 KFH46222.1 - 0.24 10.6 2.4 0.27 10.4 1.3 1.4 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel TMF_DNA_bd PF12329.3 KFH46222.1 - 0.25 11.1 42.3 1.5 8.6 11.3 3.7 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF904 PF06005.7 KFH46222.1 - 0.26 11.5 44.7 1.5 9.1 8.6 4.1 1 1 3 4 4 4 0 Protein of unknown function (DUF904) Atg14 PF10186.4 KFH46222.1 - 0.31 9.9 28.9 3.8 6.3 19.9 2.0 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Striatin PF08232.7 KFH46222.1 - 0.32 11.2 26.8 0.34 11.2 11.6 2.1 1 1 1 2 2 2 0 Striatin family CCDC155 PF14662.1 KFH46222.1 - 0.38 10.3 38.1 1.1 8.8 9.7 2.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 TBPIP PF07106.8 KFH46222.1 - 0.39 10.2 31.0 0.71 9.4 3.4 3.0 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMF_TATA_bd PF12325.3 KFH46222.1 - 0.55 9.9 33.0 3.9 7.2 2.2 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Lebercilin PF15619.1 KFH46222.1 - 0.57 9.5 36.1 0.32 10.4 14.3 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF869 PF05911.6 KFH46222.1 - 0.78 7.8 27.6 1.9 6.6 19.2 1.5 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) TPR_MLP1_2 PF07926.7 KFH46222.1 - 0.8 9.4 38.5 1.4 8.6 12.3 2.6 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Herpes_capsid PF06112.6 KFH46222.1 - 0.97 9.4 3.6 0.34 10.9 0.5 1.9 2 0 0 2 2 1 0 Gammaherpesvirus capsid protein HOOK PF05622.7 KFH46222.1 - 1 7.1 30.6 1.8 6.2 4.2 1.9 1 1 1 2 2 2 0 HOOK protein Reo_sigmaC PF04582.7 KFH46222.1 - 1.1 8.3 3.7 3.2 6.8 0.1 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF3584 PF12128.3 KFH46222.1 - 1.2 6.3 33.3 2.4 5.3 23.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) PilJ PF13675.1 KFH46222.1 - 1.4 9.2 16.1 10 6.5 5.5 2.8 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term CDC37_N PF03234.9 KFH46222.1 - 1.9 8.7 26.3 4.5 7.5 18.2 1.7 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding HTH_37 PF13744.1 KFH46222.1 - 1.9 8.3 10.2 3.9 7.3 0.7 2.7 2 1 1 3 3 3 0 Helix-turn-helix domain Fmp27_WPPW PF10359.4 KFH46222.1 - 2.1 6.6 26.3 0.25 9.7 7.3 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain IFT46_B_C PF12317.3 KFH46222.1 - 2.1 7.6 12.0 0.14 11.4 3.3 1.9 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal DUF724 PF05266.9 KFH46222.1 - 2.2 7.8 32.2 0.58 9.7 8.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Fib_alpha PF08702.5 KFH46222.1 - 2.4 8.2 20.9 0.71 9.9 5.1 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family BRE1 PF08647.6 KFH46222.1 - 2.6 8.0 32.7 2.8 7.9 6.4 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase KLRAQ PF10205.4 KFH46222.1 - 2.6 8.1 24.3 1.2 9.1 7.0 3.0 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein DivIVA PF05103.8 KFH46222.1 - 2.7 8.0 32.7 11 6.0 0.6 3.5 1 1 2 3 3 3 0 DivIVA protein WXG100 PF06013.7 KFH46222.1 - 4.4 7.3 18.9 4 7.5 0.3 4.3 2 2 2 4 4 4 0 Proteins of 100 residues with WXG Exonuc_VII_S PF02609.11 KFH46222.1 - 4.5 7.1 21.4 1.8 8.4 0.2 4.7 3 2 1 4 4 4 0 Exonuclease VII small subunit FUSC PF04632.7 KFH46222.1 - 5 5.4 6.7 6.2 5.1 4.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Rootletin PF15035.1 KFH46222.1 - 5.2 7.0 34.1 13 5.6 6.2 2.3 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion MAD PF05557.8 KFH46222.1 - 5.5 4.9 34.0 3.4 5.6 14.7 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein Cortex-I_coil PF09304.5 KFH46222.1 - 6.2 6.9 33.0 9.8 6.2 5.4 3.3 1 1 2 3 3 3 0 Cortexillin I, coiled coil NPV_P10 PF05531.7 KFH46222.1 - 6.7 7.0 12.9 5.8 7.2 0.4 3.1 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF641 PF04859.7 KFH46222.1 - 7 6.4 22.5 1.6 8.4 4.3 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) STAT_alpha PF01017.15 KFH46222.1 - 7.2 6.2 22.2 1.7e+03 -1.5 15.4 2.2 1 1 0 1 1 1 0 STAT protein, all-alpha domain Nup54 PF13874.1 KFH46222.1 - 7.8 6.1 25.9 16 5.1 5.6 2.6 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF812 PF05667.6 KFH46222.1 - 8.1 4.8 28.3 62 1.8 19.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF3287 PF11690.3 KFH46222.1 - 8.8 6.4 13.1 0.63 10.1 2.3 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3287) DUF745 PF05335.8 KFH46222.1 - 9.6 5.6 23.6 0.22 11.0 4.4 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF745) Peptidase_C78 PF07910.8 KFH46223.1 - 2.5e-60 203.3 0.0 9.9e-60 201.3 0.0 1.9 2 1 0 2 2 2 1 Peptidase family C78 zf-Di19 PF05605.7 KFH46223.1 - 0.0079 16.2 0.1 0.0079 16.2 0.1 1.9 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding Dynamin_N PF00350.18 KFH46224.1 - 1.7e-43 148.3 0.0 3.4e-43 147.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KFH46224.1 - 4.6e-12 45.3 0.3 1.6e-10 40.2 0.0 2.2 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 KFH46224.1 - 0.00047 20.0 0.0 0.0073 16.2 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFH46224.1 - 0.0027 18.1 0.0 0.0079 16.6 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein SRI PF08236.6 KFH46224.1 - 0.013 15.3 0.1 0.034 14.0 0.1 1.6 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain AAA_16 PF13191.1 KFH46224.1 - 0.068 13.1 1.3 0.48 10.3 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain AAA_21 PF13304.1 KFH46224.1 - 0.14 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KFH46225.1 - 3e-30 105.1 1.1 6.3e-30 104.1 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 KFH46225.1 - 1.2e-14 55.1 3.6 5.3e-14 53.0 2.5 1.9 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 KFH46225.1 - 3.4e-05 23.6 0.3 7.1e-05 22.5 0.1 1.6 2 0 0 2 2 2 1 NTPase AAA_33 PF13671.1 KFH46225.1 - 4.4e-05 23.3 0.2 0.0013 18.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KFH46225.1 - 4.7e-05 22.8 0.1 0.073 12.4 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase ADK PF00406.17 KFH46225.1 - 5.9e-05 22.9 0.0 0.0039 17.0 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase AAA_28 PF13521.1 KFH46225.1 - 6.2e-05 23.0 2.2 0.00014 21.8 1.5 1.9 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 KFH46225.1 - 0.00012 21.3 0.0 0.00025 20.3 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_16 PF13191.1 KFH46225.1 - 0.00014 21.8 0.0 0.00027 20.9 0.0 1.5 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 KFH46225.1 - 0.0002 21.5 0.0 0.00041 20.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SKI PF01202.17 KFH46225.1 - 0.00036 20.4 0.2 0.0025 17.6 0.1 1.9 1 1 0 1 1 1 1 Shikimate kinase AAA_22 PF13401.1 KFH46225.1 - 0.0012 19.0 0.1 0.0017 18.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain TrwB_AAD_bind PF10412.4 KFH46225.1 - 0.0014 17.3 0.0 0.0037 15.9 0.0 1.7 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain MobB PF03205.9 KFH46225.1 - 0.0018 17.9 0.0 0.0033 17.1 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KFH46225.1 - 0.0036 17.4 0.0 0.0064 16.6 0.0 1.4 1 0 0 1 1 1 1 RNA helicase FtsK_SpoIIIE PF01580.13 KFH46225.1 - 0.0059 16.1 1.0 0.012 15.1 0.0 1.9 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_10 PF12846.2 KFH46225.1 - 0.0061 16.0 0.0 0.013 14.9 0.0 1.7 1 1 0 1 1 1 1 AAA-like domain AAA_14 PF13173.1 KFH46225.1 - 0.0081 16.0 0.3 0.033 14.1 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFH46225.1 - 0.0098 15.6 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 KFH46225.1 - 0.011 15.3 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Cytidylate_kin2 PF13189.1 KFH46225.1 - 0.012 15.5 0.2 0.038 13.8 0.1 2.0 1 1 0 1 1 1 0 Cytidylate kinase-like family SRP54 PF00448.17 KFH46225.1 - 0.015 14.7 0.1 0.031 13.7 0.0 1.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain IstB_IS21 PF01695.12 KFH46225.1 - 0.016 14.6 0.0 0.031 13.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ATP_bind_1 PF03029.12 KFH46225.1 - 0.019 14.4 0.5 0.039 13.5 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ArgK PF03308.11 KFH46225.1 - 0.024 13.4 0.0 0.045 12.5 0.0 1.4 1 0 0 1 1 1 0 ArgK protein AAA_24 PF13479.1 KFH46225.1 - 0.033 13.7 0.0 0.064 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 KFH46225.1 - 0.033 13.7 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.6 KFH46225.1 - 0.035 13.6 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 KFH46225.1 - 0.044 12.6 0.0 0.076 11.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein RuvB_N PF05496.7 KFH46225.1 - 0.082 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 KFH46225.1 - 0.096 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ArsA_ATPase PF02374.10 KFH46225.1 - 2 7.3 5.4 4.7 6.1 0.1 2.6 2 1 1 3 3 3 0 Anion-transporting ATPase Peptidase_M19 PF01244.16 KFH46227.1 - 1e-96 323.6 0.0 1.4e-96 323.2 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Nop25 PF09805.4 KFH46228.1 - 3.3e-38 130.8 11.5 3.3e-38 130.8 8.0 2.4 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) Lys-AminoMut_A PF09043.6 KFH46228.1 - 0.34 8.9 1.7 0.4 8.7 0.5 1.6 2 0 0 2 2 2 0 D-Lysine 5,6-aminomutase alpha subunit DUF4202 PF13875.1 KFH46229.1 - 1.4e-72 243.2 0.0 1.6e-72 243.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) BTB PF00651.26 KFH46230.1 - 2.8e-05 24.0 0.0 7.6e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.10 KFH46230.1 - 0.14 12.2 0.0 7.5 6.7 0.0 2.3 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain N-SET PF11764.3 KFH46231.1 - 2.9e-41 141.1 0.0 2.9e-41 141.1 0.0 3.1 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.23 KFH46231.1 - 2.3e-24 86.5 0.1 2.3e-24 86.5 0.1 3.3 2 1 0 2 2 2 1 SET domain SET_assoc PF11767.3 KFH46231.1 - 7.9e-22 76.3 1.2 1.6e-21 75.3 0.1 2.1 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated IGR PF09597.5 KFH46232.1 - 2e-23 82.0 0.1 3.9e-23 81.0 0.1 1.5 1 0 0 1 1 1 1 IGR protein motif zf-MYND PF01753.13 KFH46233.1 - 4e-07 29.8 20.7 4e-07 29.8 14.3 1.9 2 0 0 2 2 2 1 MYND finger AMP-binding PF00501.23 KFH46234.1 - 4.2e-86 288.9 0.0 5.3e-86 288.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFH46234.1 - 1.4e-09 38.7 0.0 3.1e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AAA_2 PF07724.9 KFH46234.1 - 0.17 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) bZIP_2 PF07716.10 KFH46235.1 - 0.0012 18.6 11.8 0.0018 18.0 8.2 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KFH46235.1 - 0.006 16.5 8.7 0.0098 15.8 6.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor Milton PF12448.3 KFH46235.1 - 1.2 9.2 13.3 0.07 13.3 4.8 2.0 2 1 0 2 2 2 0 Kinesin associated protein Pro_isomerase PF00160.16 KFH46236.1 - 1.8e-46 158.1 0.6 2.3e-46 157.8 0.4 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Polyketide_cyc PF03364.15 KFH46237.1 - 7.8e-25 87.3 0.1 1.1e-24 86.8 0.1 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Peptidase_S28 PF05577.7 KFH46238.1 - 3.9e-38 131.1 0.2 2.2e-30 105.6 0.1 2.9 2 1 0 2 2 2 2 Serine carboxypeptidase S28 Cyanate_lyase PF02560.9 KFH46239.1 - 5.3e-31 105.9 0.0 7.3e-31 105.5 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.1 KFH46239.1 - 0.061 13.5 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Abhydrolase_6 PF12697.2 KFH46242.1 - 1.5e-30 106.7 0.0 2e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFH46242.1 - 5.7e-18 65.3 0.0 2.3e-17 63.3 0.0 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFH46242.1 - 2.7e-14 53.1 0.0 4.3e-14 52.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KFH46242.1 - 1e-06 28.4 0.0 1.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.15 KFH46242.1 - 0.0002 20.8 0.0 0.00039 19.9 0.0 1.5 2 0 0 2 2 2 1 Putative esterase Thioesterase PF00975.15 KFH46242.1 - 0.0015 18.8 0.0 0.0019 18.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 KFH46242.1 - 0.0017 18.1 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase DUF676 PF05057.9 KFH46242.1 - 0.018 14.3 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF2048 PF09752.4 KFH46242.1 - 0.029 13.2 0.0 0.056 12.3 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) DLH PF01738.13 KFH46242.1 - 0.031 13.5 0.0 0.37 10.0 0.0 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family Chlorophyllase PF07224.6 KFH46242.1 - 0.08 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Lipase_3 PF01764.20 KFH46242.1 - 0.1 12.2 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) CTP_transf_2 PF01467.21 KFH46243.1 - 0.0017 18.4 0.6 0.4 10.7 0.3 2.6 2 0 0 2 2 2 2 Cytidylyltransferase Pheromone PF08015.6 KFH46243.1 - 0.066 14.0 4.4 1.1 10.1 0.0 4.1 4 0 0 4 4 4 0 Fungal mating-type pheromone FAD_syn PF06574.7 KFH46243.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 FAD synthetase Aldedh PF00171.17 KFH46244.1 - 1.7e-161 537.6 0.0 1.9e-161 537.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KFH46244.1 - 0.00078 18.2 0.0 0.0016 17.2 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 KFH46244.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) ATP-synt_S1 PF05827.7 KFH46245.1 - 1.5e-37 129.4 0.0 4e-36 124.7 0.0 2.0 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) FMN_dh PF01070.13 KFH46246.1 - 4.2e-115 384.3 0.1 5e-115 384.1 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 KFH46246.1 - 4.4e-05 22.7 0.1 7.7e-05 21.9 0.1 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.12 KFH46246.1 - 0.00013 21.0 0.7 0.00033 19.6 0.4 1.8 1 1 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KFH46246.1 - 0.00019 20.4 1.6 0.003 16.4 0.6 2.7 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 KFH46246.1 - 0.0028 16.7 0.1 0.19 10.7 0.0 2.2 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG DHO_dh PF01180.16 KFH46246.1 - 0.12 11.2 0.5 8.1 5.2 0.0 2.8 3 0 0 3 3 3 0 Dihydroorotate dehydrogenase His_biosynth PF00977.16 KFH46246.1 - 0.14 11.4 0.1 3.2 6.9 0.0 2.5 2 1 1 3 3 3 0 Histidine biosynthesis protein Mid1 PF12929.2 KFH46247.1 - 6.1e-116 387.6 0.6 7.2e-116 387.3 0.4 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 KFH46247.1 - 0.028 14.7 4.7 0.4 11.0 0.2 2.5 2 0 0 2 2 2 0 Fz domain MFS_1 PF07690.11 KFH46248.1 - 3.3e-33 114.8 38.6 9.2e-33 113.4 25.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily ESSS PF10183.4 KFH46248.1 - 0.039 14.3 2.9 0.048 14.0 0.5 2.3 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) SMAP PF15477.1 KFH46249.1 - 4.5e-13 49.2 3.6 4.5e-13 49.2 2.5 6.2 4 3 0 4 4 4 1 Small acidic protein family DUF4023 PF13215.1 KFH46250.1 - 0.19 11.5 0.2 5.2 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4023) Tetraspannin PF00335.15 KFH46250.1 - 0.47 9.6 8.3 1.4 8.1 0.0 2.9 3 0 0 3 3 3 0 Tetraspanin family adh_short PF00106.20 KFH46251.1 - 2e-28 99.4 0.7 2.4e-28 99.1 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH46251.1 - 3.1e-21 76.2 0.0 4.5e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH46251.1 - 1.2e-12 47.8 0.3 1.7e-12 47.3 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFH46251.1 - 0.035 13.5 0.1 0.095 12.1 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.16 KFH46251.1 - 0.056 13.2 0.0 0.088 12.6 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF3812 PF12757.2 KFH46252.1 - 8.3e-34 116.2 12.2 8.3e-34 116.2 8.4 4.3 2 2 1 3 3 3 1 Protein of unknown function (DUF3812) GDPD_2 PF13653.1 KFH46254.1 - 0.089 13.0 0.2 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family AA_kinase PF00696.23 KFH46255.1 - 3.3e-32 111.9 0.0 6.1e-32 111.0 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 KFH46255.1 - 2.7e-14 52.2 1.9 1.5e-08 33.9 0.1 2.6 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 KFH46255.1 - 1.7e-13 49.8 5.1 1.1e-09 37.6 0.2 2.9 2 1 1 3 3 3 2 ACT domain RAMP4 PF06624.7 KFH46256.1 - 0.0044 16.5 0.0 0.0056 16.1 0.0 1.3 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 SHP PF03579.8 KFH46256.1 - 0.041 13.2 1.3 0.052 12.8 0.9 1.2 1 0 0 1 1 1 0 Small hydrophobic protein TRAP_alpha PF03896.11 KFH46257.1 - 1.2e-07 31.0 0.5 3.4e-07 29.5 0.3 1.8 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit UQ_con PF00179.21 KFH46259.1 - 1.6e-22 79.4 0.0 2.8e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KFH46259.1 - 0.001 18.9 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 RWD domain DUF2072 PF09845.4 KFH46259.1 - 0.059 13.2 1.8 0.095 12.6 1.3 1.2 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Fungal_trans PF04082.13 KFH46260.1 - 1.3e-21 76.6 0.0 2.1e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH46260.1 - 0.00011 22.0 10.5 0.0002 21.2 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.24 KFH46261.1 - 6.5e-46 155.9 0.0 1e-45 155.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFH46261.1 - 4.3e-26 90.5 0.0 7.6e-26 89.7 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFH46261.1 - 0.00034 20.5 0.0 0.0023 17.7 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Cation_efflux PF01545.16 KFH46262.1 - 3.4e-28 98.5 10.6 4.4e-28 98.1 7.3 1.0 1 0 0 1 1 1 1 Cation efflux family PP2C PF00481.16 KFH46263.1 - 9.9e-35 120.1 0.0 1.5e-34 119.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KFH46263.1 - 0.00055 19.7 0.0 3.7 7.2 0.0 3.3 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KFH46263.1 - 0.019 14.3 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein phosphatase 2C B-block_TFIIIC PF04182.7 KFH46264.1 - 4.5e-12 45.6 0.0 1.1e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC AT_hook PF02178.14 KFH46264.1 - 0.0018 17.7 43.1 0.2 11.4 3.6 5.1 5 0 0 5 5 5 4 AT hook motif HTH_27 PF13463.1 KFH46264.1 - 0.038 14.3 0.1 0.12 12.7 0.0 1.9 2 0 0 2 2 2 0 Winged helix DNA-binding domain Pyr_redox_3 PF13738.1 KFH46265.1 - 1.4e-24 87.3 0.0 4.8e-24 85.5 0.0 1.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFH46265.1 - 6.3e-18 64.2 0.1 5.3e-15 54.6 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KFH46265.1 - 8.5e-12 44.9 0.0 2.2e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KFH46265.1 - 2.2e-07 30.1 0.0 0.0012 17.8 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KFH46265.1 - 1.7e-05 24.6 0.3 6.1e-05 22.8 0.0 2.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 KFH46265.1 - 0.0051 15.7 0.0 0.011 14.7 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF4188 PF13826.1 KFH46265.1 - 0.024 14.7 0.0 0.67 10.0 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4188) Thi4 PF01946.12 KFH46265.1 - 0.025 13.6 0.0 0.29 10.2 0.0 2.4 2 1 1 3 3 3 0 Thi4 family GTP_CH_N PF12471.3 KFH46267.1 - 2.8e-67 226.1 0.0 4.2e-67 225.5 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 KFH46267.1 - 2.8e-14 52.7 0.1 9.5e-09 34.7 0.0 2.3 2 0 0 2 2 2 2 GTP cyclohydrolase II GntR PF00392.16 KFH46267.1 - 0.036 13.5 0.1 2.7 7.5 0.0 3.2 4 0 0 4 4 4 0 Bacterial regulatory proteins, gntR family Methyltransf_12 PF08242.7 KFH46268.1 - 5.9e-13 49.1 0.0 1.3e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH46268.1 - 6.6e-11 42.5 0.0 1.3e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH46268.1 - 1.2e-09 38.1 0.0 2.5e-09 37.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH46268.1 - 9.4e-08 32.6 0.0 1.7e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFH46268.1 - 1.1e-07 32.1 0.0 2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH46268.1 - 1.3e-06 28.1 0.0 2.2e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFH46268.1 - 0.00011 21.3 0.0 0.00016 20.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KFH46268.1 - 0.00018 21.4 0.1 0.00036 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 KFH46268.1 - 0.0019 19.0 0.0 0.0047 17.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KFH46268.1 - 0.0029 17.2 0.0 0.072 12.7 0.0 2.6 1 1 0 1 1 1 1 Hypothetical methyltransferase DUF3419 PF11899.3 KFH46268.1 - 0.015 14.0 0.0 0.023 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) MTS PF05175.9 KFH46268.1 - 0.019 14.3 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.12 KFH46268.1 - 0.06 12.3 0.0 6.4 5.6 0.0 2.2 1 1 0 2 2 2 0 NNMT/PNMT/TEMT family 2-Hacid_dh_C PF02826.14 KFH46270.1 - 9.4e-53 177.9 0.0 1.5e-52 177.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFH46270.1 - 1.5e-33 115.1 0.1 2e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KFH46270.1 - 9e-07 28.8 1.7 3.4e-06 27.0 0.2 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 KFH46270.1 - 0.00083 19.2 0.1 0.0019 18.0 0.1 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 KFH46270.1 - 0.00088 18.6 0.0 0.0021 17.4 0.0 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain ACT PF01842.20 KFH46270.1 - 0.0092 15.4 0.0 0.025 14.0 0.0 1.8 1 0 0 1 1 1 1 ACT domain Elf1 PF05129.8 KFH46271.1 - 1.3e-24 85.6 3.5 3.4e-24 84.3 2.4 1.6 1 1 0 1 1 1 1 Transcription elongation factor Elf1 like Cys_rich_CPXG PF14255.1 KFH46271.1 - 0.047 13.5 1.5 0.084 12.7 1.1 1.4 1 0 0 1 1 1 0 Cysteine-rich CPXCG zf-Sec23_Sec24 PF04810.10 KFH46271.1 - 0.26 10.8 0.2 0.26 10.8 0.1 2.2 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger Pkinase PF00069.20 KFH46272.1 - 5.2e-63 212.6 0.0 6.3e-63 212.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH46272.1 - 1.7e-34 119.0 0.0 2.2e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH46272.1 - 0.0033 16.4 0.0 0.0078 15.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like P5-ATPase PF12409.3 KFH46273.1 - 1.7e-36 124.6 0.0 3.5e-36 123.6 0.0 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter HAD PF12710.2 KFH46273.1 - 1.7e-30 106.6 0.0 3.6e-30 105.5 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KFH46273.1 - 4e-25 88.2 0.0 8.3e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KFH46273.1 - 2e-19 70.8 0.0 1e-18 68.5 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFH46273.1 - 0.0067 15.8 0.0 0.016 14.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KFH46273.1 - 0.043 13.3 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAMP PF00672.20 KFH46273.1 - 0.24 11.6 2.4 1 9.6 0.1 3.3 3 0 0 3 3 3 0 HAMP domain WAPL PF07814.8 KFH46274.1 - 4.7e-11 42.0 0.6 8.6e-11 41.1 0.2 1.6 2 0 0 2 2 2 1 Wings apart-like protein regulation of heterochromatin Spb1_C PF07780.7 KFH46275.1 - 6e-72 241.6 26.1 6e-72 241.6 18.1 3.9 3 1 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.3 KFH46275.1 - 4.1e-56 188.8 12.1 4.1e-56 188.8 8.4 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF3381) FtsJ PF01728.14 KFH46275.1 - 2.6e-54 183.9 0.0 4.9e-54 183.0 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase tRNA-synt_2b PF00587.20 KFH46276.1 - 7.3e-24 84.2 0.0 1.3e-23 83.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KFH46276.1 - 1.8e-19 69.7 5.4 3.8e-19 68.6 3.7 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Ribosomal_S13 PF00416.17 KFH46278.1 - 3.8e-24 85.1 0.1 4.7e-24 84.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Ham1p_like PF01725.11 KFH46280.1 - 1.1e-47 161.8 0.0 1.3e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 Ham1 family Sterol-sensing PF12349.3 KFH46281.1 - 2.3e-36 124.5 10.9 5.3e-36 123.3 7.6 1.7 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 KFH46281.1 - 2.5e-12 45.5 9.7 3.7e-12 45.0 6.7 1.1 1 0 0 1 1 1 1 Patched family GTP_CH_N PF12471.3 KFH46282.1 - 8.7e-14 51.5 0.0 1.2e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal DUF892 PF05974.7 KFH46282.1 - 0.092 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF892) DUF3618 PF12277.3 KFH46282.1 - 0.18 11.8 0.8 1.2 9.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) DUF2392 PF10288.4 KFH46283.1 - 0.034 14.4 0.1 0.13 12.6 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2392) Ribosomal_S3Ae PF01015.13 KFH46285.1 - 2.1e-77 258.8 3.5 2.7e-77 258.5 2.4 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Erythro-docking PF09277.6 KFH46285.1 - 0.026 14.2 0.2 10 5.9 0.1 2.7 2 0 0 2 2 2 0 Erythronolide synthase, docking Ebp2 PF05890.7 KFH46286.1 - 2.1e-94 315.8 9.8 2.1e-94 315.8 6.8 2.1 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 DUF1980 PF09323.5 KFH46286.1 - 1.1 8.9 2.7 3.1 7.4 1.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Acyl-CoA_dh_1 PF00441.19 KFH46287.1 - 2.4e-23 82.8 0.1 3.8e-23 82.2 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFH46287.1 - 9.2e-12 45.5 0.0 2.3e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KFH46287.1 - 1e-07 32.2 0.0 2.3e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFH46287.1 - 1.2e-07 31.0 0.0 3.1e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain SNF2_N PF00176.18 KFH46288.1 - 1.2e-53 181.8 0.0 2.9e-53 180.6 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 KFH46288.1 - 1.1e-09 37.8 10.0 2.4e-09 36.8 6.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFH46288.1 - 2.8e-08 33.3 9.8 5.6e-08 32.3 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFH46288.1 - 4e-07 29.9 10.4 8.3e-07 28.9 7.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFH46288.1 - 1.1e-06 28.1 9.8 2.2e-06 27.2 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFH46288.1 - 8.3e-06 25.4 10.0 1.5e-05 24.6 6.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KFH46288.1 - 0.00011 22.2 9.6 0.00031 20.7 6.7 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KFH46288.1 - 0.0088 15.7 5.3 0.011 15.3 2.6 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFH46288.1 - 0.013 15.3 9.0 0.028 14.2 6.3 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Helicase_C PF00271.26 KFH46288.1 - 0.02 14.7 0.0 0.052 13.4 0.0 1.7 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Prok-RING_4 PF14447.1 KFH46288.1 - 0.04 13.4 4.7 0.095 12.2 3.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 KFH46288.1 - 0.042 13.4 6.5 0.12 12.0 4.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.6 KFH46288.1 - 0.24 11.1 2.6 0.61 9.8 1.8 1.6 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-Apc11 PF12861.2 KFH46288.1 - 1.2 9.0 7.5 4.2 7.2 5.2 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.2 KFH46288.1 - 2.2 8.1 6.3 7.1 6.5 4.4 1.8 1 1 0 1 1 1 0 Double zinc ribbon CsbD PF05532.7 KFH46289.1 - 1.8e-06 27.5 8.8 0.0033 17.0 1.1 2.1 2 0 0 2 2 2 2 CsbD-like zf-UBR PF02207.15 KFH46290.1 - 0.47 10.2 2.9 12 5.6 0.0 2.2 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) PAPS_reduct PF01507.14 KFH46291.1 - 3.9e-30 104.9 0.0 4.4e-21 75.4 0.0 2.2 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family Y_phosphatase3 PF13350.1 KFH46292.1 - 2.1e-26 93.1 1.5 1.1e-12 48.4 0.0 2.2 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 KFH46292.1 - 1.1e-08 35.1 0.1 2.9e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 KFH46292.1 - 0.012 14.9 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Myotub-related PF06602.9 KFH46292.1 - 0.078 11.7 0.1 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Y_phosphatase2 PF03162.8 KFH46292.1 - 0.099 11.9 0.1 0.35 10.2 0.0 1.8 2 0 0 2 2 2 0 Tyrosine phosphatase family Cupin_8 PF13621.1 KFH46293.1 - 4.4e-59 200.0 0.0 5.9e-59 199.6 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KFH46293.1 - 0.00017 20.9 0.0 0.00088 18.6 0.0 1.9 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.17 KFH46293.1 - 0.0091 16.2 0.0 0.17 12.1 0.0 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase Peptidase_M90 PF06167.7 KFH46297.1 - 0.13 11.6 2.0 1.3 8.3 1.4 2.0 1 1 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 Frag1 PF10277.4 KFH46298.1 - 7.2e-42 143.3 18.2 8.2e-42 143.1 12.6 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Pox_P21 PF05313.7 KFH46298.1 - 0.27 10.4 4.8 0.47 9.6 0.1 2.1 2 0 0 2 2 2 0 Poxvirus P21 membrane protein Pox_A14 PF05767.7 KFH46298.1 - 4.5 7.3 7.1 0.88 9.5 0.3 2.7 1 1 2 3 3 3 0 Poxvirus virion envelope protein A14 Trm112p PF03966.11 KFH46299.1 - 6.7e-17 61.6 0.1 8.7e-17 61.2 0.1 1.2 1 0 0 1 1 1 1 Trm112p-like protein Zn_ribbon_recom PF13408.1 KFH46299.1 - 0.048 13.9 0.2 0.093 13.0 0.1 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-NADH-PPase PF09297.6 KFH46299.1 - 0.069 12.6 0.1 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain DUF1451 PF07295.6 KFH46299.1 - 0.12 12.1 0.1 0.24 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) TB2_DP1_HVA22 PF03134.14 KFH46301.1 - 1.4e-30 104.8 5.7 1.9e-30 104.4 4.0 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Alpha_GJ PF03229.8 KFH46302.1 - 0.023 15.0 4.4 0.023 15.0 3.1 2.2 2 1 0 2 2 2 0 Alphavirus glycoprotein J DUF1628 PF07790.6 KFH46302.1 - 0.83 10.4 3.4 2.8 8.7 2.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1628) ExoD PF06055.7 KFH46303.1 - 0.093 11.8 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD 14-3-3 PF00244.15 KFH46304.1 - 7.3e-07 28.5 0.1 1.5e-06 27.5 0.0 1.4 2 0 0 2 2 2 1 14-3-3 protein EF-hand_1 PF00036.27 KFH46306.1 - 7.6e-40 131.1 16.7 4.5e-10 38.0 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 KFH46306.1 - 1.6e-35 120.4 16.6 4e-15 55.1 0.6 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_7 PF13499.1 KFH46306.1 - 6.3e-34 115.9 7.6 1.5e-18 66.6 1.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFH46306.1 - 2.2e-31 104.8 12.6 1.6e-09 36.8 0.0 4.3 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KFH46306.1 - 2.9e-28 95.9 14.5 5.5e-08 31.8 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 KFH46306.1 - 1e-16 60.5 0.1 8.9e-08 31.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KFH46306.1 - 2.5e-12 46.4 0.7 3.2e-05 23.5 0.1 2.1 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.8 KFH46306.1 - 1.7e-08 33.9 0.1 0.00071 19.1 0.0 2.8 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) SPARC_Ca_bdg PF10591.4 KFH46306.1 - 2.6e-07 30.6 0.1 0.008 16.1 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region RNA_pol_Rpb4 PF03874.11 KFH46306.1 - 0.00034 20.5 1.2 0.025 14.5 0.3 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb4 TerB PF05099.8 KFH46306.1 - 0.0013 18.4 0.1 0.047 13.4 0.0 2.1 1 1 1 2 2 2 1 Tellurite resistance protein TerB Caleosin PF05042.8 KFH46306.1 - 0.013 15.0 0.0 0.47 9.9 0.0 2.3 2 1 0 2 2 2 0 Caleosin related protein DUF1456 PF07308.8 KFH46306.1 - 0.038 14.0 0.2 3.2 7.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) Tenui_NCP PF04876.7 KFH46306.1 - 0.05 13.1 0.2 4.5 6.7 0.0 2.2 1 1 0 2 2 2 0 Tenuivirus major non-capsid protein Acetyltransf_11 PF13720.1 KFH46306.1 - 0.069 13.3 0.0 0.6 10.3 0.0 2.0 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Toprim_2 PF13155.1 KFH46306.1 - 0.084 13.1 1.0 3.7 7.9 0.0 2.5 2 1 0 2 2 2 0 Toprim-like DUF853 PF05872.7 KFH46306.1 - 0.097 11.0 0.1 4.5 5.4 0.0 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) DUF2267 PF10025.4 KFH46306.1 - 0.12 12.4 0.0 0.56 10.2 0.0 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) DUF2376 PF09550.5 KFH46306.1 - 0.12 12.5 0.1 7 6.8 0.0 3.3 3 1 0 4 4 4 0 Conserved hypothetical phage protein (DUF2376) Fe_hyd_lg_C PF02906.9 KFH46306.1 - 0.12 11.6 0.2 0.32 10.2 0.2 1.7 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain RNase_PH_C PF03725.10 KFH46306.1 - 0.35 10.8 3.0 1.9 8.5 2.0 2.4 1 1 0 1 1 1 0 3' exoribonuclease family, domain 2 VCBS PF13517.1 KFH46306.1 - 1 9.7 4.0 1.5 9.1 0.3 2.4 1 1 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EF-hand_10 PF14788.1 KFH46306.1 - 2.8 7.6 5.4 3.9 7.2 0.5 3.0 2 2 1 3 3 3 0 EF hand RFX_DNA_binding PF02257.10 KFH46307.1 - 6.8e-30 103.0 0.1 1.2e-29 102.2 0.0 1.4 1 0 0 1 1 1 1 RFX DNA-binding domain NADH_B2 PF14813.1 KFH46308.1 - 0.62 9.7 3.1 0.63 9.7 2.2 1.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 adh_short PF00106.20 KFH46309.1 - 2.7e-24 85.9 0.0 3.7e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH46309.1 - 2.6e-19 69.9 0.0 4.3e-19 69.2 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH46309.1 - 1.1e-10 41.5 0.0 1.6e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.18 KFH46309.1 - 0.03 14.1 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 KFH46309.1 - 0.046 12.6 0.0 0.071 11.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ThiF PF00899.16 KFH46309.1 - 0.049 13.4 0.2 1.3 8.8 0.0 2.4 1 1 1 2 2 2 0 ThiF family Sec10 PF07393.6 KFH46310.1 - 2.3e-156 521.9 0.0 2.9e-156 521.6 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 KFH46310.1 - 3.1e-06 26.7 0.1 9.1e-06 25.3 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFH46310.1 - 5.4e-05 22.7 0.0 9.7e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 F-box domain DUF4072 PF13284.1 KFH46310.1 - 0.1 12.8 1.3 5.9 7.1 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4072) RhoGAP PF00620.22 KFH46312.1 - 1.1e-16 60.8 0.0 2.7e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 KFH46312.1 - 4.9e-15 55.4 0.5 2.6e-14 53.1 0.0 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 KFH46312.1 - 1.5e-11 43.8 0.0 3.5e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF3993 PF13158.1 KFH46312.1 - 0.021 14.5 0.1 0.062 13.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3993) Adaptin_N PF01602.15 KFH46315.1 - 6.6e-73 245.8 0.0 1.7e-72 244.4 0.0 1.7 1 1 0 1 1 1 1 Adaptin N terminal region TPR_16 PF13432.1 KFH46316.1 - 1.2e-08 35.3 0.8 0.0004 20.9 0.0 4.2 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFH46316.1 - 3.6e-08 33.6 0.2 1.5e-05 25.1 0.0 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFH46316.1 - 1.3e-07 31.1 0.0 9.4e-06 25.1 0.0 3.0 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 KFH46316.1 - 3.5e-07 29.6 0.0 0.0011 18.6 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFH46316.1 - 6.5e-06 26.3 9.8 0.0079 16.7 0.2 4.7 4 2 1 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFH46316.1 - 1.1e-05 24.9 0.2 0.33 10.8 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFH46316.1 - 0.00012 22.2 0.1 15 6.2 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFH46316.1 - 0.00025 20.5 0.2 0.024 14.3 0.1 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFH46316.1 - 0.001 18.5 0.0 0.11 12.1 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFH46316.1 - 0.0055 16.6 2.9 1.1 9.2 0.2 3.4 2 2 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFH46316.1 - 0.009 15.8 0.3 17 5.3 0.0 3.4 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.1 KFH46316.1 - 0.027 14.5 3.1 0.98 9.5 0.0 3.6 2 1 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 KFH46316.1 - 0.03 14.4 0.1 0.1 12.7 0.0 2.0 2 0 0 2 2 1 0 Anaphase-promoting complex, cyclosome, subunit 3 HTH_16 PF12645.2 KFH46316.1 - 0.032 14.1 0.0 0.096 12.6 0.0 1.7 2 0 0 2 2 1 0 Helix-turn-helix domain BTAD PF03704.12 KFH46316.1 - 0.097 12.9 5.6 6.8 6.9 0.0 3.2 2 1 0 3 3 3 0 Bacterial transcriptional activator domain Brix PF04427.13 KFH46317.1 - 4.5e-57 192.7 0.0 5.9e-57 192.4 0.0 1.1 1 0 0 1 1 1 1 Brix domain Peptidase_S49_N PF08496.5 KFH46317.1 - 3.5 7.3 5.8 8.4 6.1 4.0 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Myosin_head PF00063.16 KFH46318.1 - 1.6e-243 809.8 0.6 2.7e-243 809.0 0.4 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.14 KFH46318.1 - 8.2e-35 118.8 3.1 2.8e-34 117.1 2.1 2.0 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 KFH46318.1 - 1.5e-11 42.8 41.1 0.0002 20.6 1.2 6.4 6 0 0 6 6 6 5 IQ calmodulin-binding motif Reo_sigmaC PF04582.7 KFH46318.1 - 5e-08 32.5 1.6 9.3e-08 31.6 1.1 1.4 1 0 0 1 1 1 1 Reovirus sigma C capsid protein AAA_22 PF13401.1 KFH46318.1 - 0.0016 18.5 0.0 0.0069 16.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFH46318.1 - 0.012 15.3 0.0 0.039 13.7 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain GAS PF13851.1 KFH46318.1 - 0.045 12.9 27.4 0.42 9.7 6.5 2.7 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Myosin_N PF02736.14 KFH46318.1 - 0.048 13.3 0.9 0.14 11.8 0.6 1.8 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain Baculo_PEP_C PF04513.7 KFH46318.1 - 0.13 12.0 5.2 0.11 12.3 1.7 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Flagellin_N PF00669.15 KFH46318.1 - 0.35 10.6 11.5 0.026 14.3 3.7 2.3 2 1 0 2 2 1 0 Bacterial flagellin N-terminal helical region Fib_alpha PF08702.5 KFH46318.1 - 3.1 7.8 11.4 3.1 7.9 5.8 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.2 KFH46318.1 - 3.9 7.3 26.7 2.7 7.8 4.2 2.6 1 1 1 2 2 2 0 Tropomyosin like DUF972 PF06156.8 KFH46318.1 - 9.2 6.6 18.3 77 3.6 5.2 3.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) UPRTase PF14681.1 KFH46319.1 - 5.6e-79 264.1 0.0 7e-79 263.8 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KFH46319.1 - 0.00043 20.0 0.0 0.00063 19.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 KFH46319.1 - 0.13 11.9 0.1 0.22 11.2 0.1 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) DND1_DSRM PF14709.1 KFH46320.1 - 0.033 14.4 0.0 0.07 13.4 0.0 1.5 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 HECT PF00632.20 KFH46321.1 - 1.2e-79 267.8 0.0 1.7e-79 267.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 KFH46321.1 - 0.0019 17.6 0.6 0.006 16.1 0.4 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif HAD_2 PF13419.1 KFH46321.1 - 0.094 12.9 0.3 1 9.5 0.3 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase NMO PF03060.10 KFH46322.1 - 5.1e-59 200.0 0.1 7.9e-59 199.4 0.0 1.3 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KFH46322.1 - 6.4e-10 38.4 0.0 0.00039 19.4 0.0 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain DUF1902 PF08972.6 KFH46322.1 - 0.12 11.9 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) FMN_dh PF01070.13 KFH46322.1 - 0.12 11.2 0.2 0.21 10.4 0.1 1.4 1 0 0 1 1 1 0 FMN-dependent dehydrogenase SCP2_2 PF13530.1 KFH46324.1 - 0.09 12.1 0.5 0.11 11.8 0.3 1.2 1 0 0 1 1 1 0 Sterol carrier protein domain Transket_pyr PF02779.19 KFH46325.1 - 9e-41 139.3 0.0 1.6e-40 138.4 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KFH46325.1 - 4e-31 107.5 0.7 1.2e-30 106.0 0.0 2.1 3 0 0 3 3 3 1 Transketolase, C-terminal domain p450 PF00067.17 KFH46326.1 - 1.2e-38 132.9 0.0 2e-38 132.1 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Copper-fist PF00649.13 KFH46327.1 - 3.4e-11 42.1 1.0 8.1e-11 40.9 0.7 1.7 1 0 0 1 1 1 1 Copper fist DNA binding domain PhyH PF05721.8 KFH46328.1 - 3.6e-07 30.4 0.1 6e-07 29.7 0.1 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PAP1 PF08601.5 KFH46329.1 - 1.5e-35 123.5 29.4 3e-22 79.8 18.6 3.5 2 1 2 4 4 3 2 Transcription factor PAP1 bZIP_1 PF00170.16 KFH46329.1 - 8.5e-10 38.4 11.6 2e-09 37.2 8.1 1.6 1 0 0 1 1 1 1 bZIP transcription factor CENP-F_leu_zip PF10473.4 KFH46329.1 - 0.00041 20.2 1.5 0.00041 20.2 1.1 1.8 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_2 PF07716.10 KFH46329.1 - 0.002 17.9 12.9 0.0064 16.2 8.9 1.8 1 1 0 1 1 1 1 Basic region leucine zipper GAS PF13851.1 KFH46329.1 - 0.016 14.4 6.5 0.032 13.4 4.5 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Cluap1 PF10234.4 KFH46329.1 - 0.045 12.9 6.1 0.081 12.1 4.3 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 Herpes_UL6 PF01763.11 KFH46329.1 - 0.054 11.6 2.6 0.083 11.0 1.8 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF904 PF06005.7 KFH46329.1 - 0.089 13.0 6.9 0.2 11.9 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) TMF_DNA_bd PF12329.3 KFH46329.1 - 0.09 12.5 7.8 0.18 11.6 5.4 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 KFH46329.1 - 0.14 11.1 4.1 0.22 10.5 2.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Prefoldin PF02996.12 KFH46329.1 - 0.16 11.6 4.0 0.27 10.8 2.7 1.3 1 0 0 1 1 1 0 Prefoldin subunit DUF2935 PF11155.3 KFH46329.1 - 0.2 11.7 3.1 5.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) HrpB7 PF09486.5 KFH46329.1 - 0.21 11.5 5.2 0.36 10.7 3.6 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) CENP-H PF05837.7 KFH46329.1 - 0.46 10.6 5.4 1.1 9.4 3.7 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Adeno_PIX PF03955.9 KFH46329.1 - 0.52 10.8 6.7 0.054 14.0 1.3 1.8 2 0 0 2 2 1 0 Adenovirus hexon-associated protein (IX) Snapin_Pallidin PF14712.1 KFH46329.1 - 0.75 10.1 5.6 1.3 9.4 1.5 2.4 2 0 0 2 2 2 0 Snapin/Pallidin Prominin PF05478.6 KFH46329.1 - 0.99 6.8 2.4 1.5 6.2 1.7 1.2 1 0 0 1 1 1 0 Prominin DUF972 PF06156.8 KFH46329.1 - 1.4 9.2 5.7 0.34 11.2 1.4 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF972) IncA PF04156.9 KFH46329.1 - 1.5 8.4 6.5 3.2 7.3 4.5 1.5 1 0 0 1 1 1 0 IncA protein XhlA PF10779.4 KFH46329.1 - 1.8 8.5 5.3 3.2 7.7 3.7 1.3 1 0 0 1 1 1 0 Haemolysin XhlA Tmemb_cc2 PF10267.4 KFH46329.1 - 4.7 5.6 20.0 0.045 12.3 5.1 2.1 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein MFS_1 PF07690.11 KFH46330.1 - 1.2e-36 126.1 40.3 3.7e-36 124.5 24.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH46330.1 - 9.4e-12 44.2 8.5 9.4e-12 44.2 5.9 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KFH46330.1 - 8.4e-06 24.2 2.2 8.4e-06 24.2 1.5 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 KFH46330.1 - 0.0017 16.5 0.5 0.0017 16.5 0.4 1.6 2 0 0 2 2 2 1 Transmembrane secretion effector DUF3353 PF11833.3 KFH46330.1 - 0.11 11.9 0.7 2.3 7.6 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3353) RPN7 PF10602.4 KFH46331.1 - 4.2e-56 189.1 0.5 8.8e-56 188.0 0.1 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 KFH46331.1 - 2.7e-15 56.5 0.0 6.1e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 PCI domain Cellulase PF00150.13 KFH46332.1 - 2e-30 105.9 1.6 1.4e-15 57.2 0.2 2.4 3 0 0 3 3 3 2 Cellulase (glycosyl hydrolase family 5) Methyltransf_16 PF10294.4 KFH46333.1 - 2.1e-13 50.1 0.0 1.1e-09 37.9 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 KFH46333.1 - 0.00034 21.1 0.0 0.00065 20.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFH46333.1 - 0.0028 16.8 0.0 0.0042 16.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Glyco_hydro_3 PF00933.16 KFH46334.1 - 1.8e-55 188.0 0.0 2.6e-55 187.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.19 KFH46334.1 - 3.3e-05 23.8 0.3 0.00017 21.5 0.0 2.3 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family Glyco_hydro_3_C PF01915.17 KFH46334.1 - 0.00032 20.3 0.0 0.00054 19.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_7 PF13508.1 KFH46334.1 - 0.00068 19.7 0.0 0.002 18.2 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Fe_hyd_SSU PF02256.12 KFH46334.1 - 0.0032 17.4 0.0 2.3 8.3 0.0 2.7 2 0 0 2 2 2 2 Iron hydrogenase small subunit adh_short PF00106.20 KFH46335.1 - 2.3e-29 102.4 3.1 6.3e-29 101.0 2.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH46335.1 - 4.8e-18 65.8 0.1 2.3e-15 57.0 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH46335.1 - 1.7e-13 50.6 1.5 4.1e-13 49.3 1.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KFH46335.1 - 0.00032 20.2 0.2 0.0033 16.9 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 KFH46335.1 - 0.015 14.4 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ETF_QO PF05187.8 KFH46337.1 - 3.3e-44 149.3 0.0 5.6e-44 148.6 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 KFH46337.1 - 2.9e-08 33.0 0.0 0.00019 20.4 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFH46337.1 - 2.3e-07 30.7 0.0 6.3e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KFH46337.1 - 2.9e-05 23.0 1.2 0.0019 17.1 0.8 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KFH46337.1 - 7.2e-05 22.7 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFH46337.1 - 0.00019 20.5 0.0 0.00053 19.1 0.0 1.6 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 KFH46337.1 - 0.00052 19.1 0.0 0.00075 18.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KFH46337.1 - 0.00056 19.0 0.0 0.00099 18.2 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KFH46337.1 - 0.0007 18.1 0.6 0.0011 17.5 0.4 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 KFH46337.1 - 0.00081 19.7 0.0 4.1 7.8 0.0 3.2 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFH46337.1 - 0.00081 19.1 0.3 0.0027 17.4 0.2 1.9 1 1 0 1 1 1 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KFH46337.1 - 0.0013 17.4 0.0 0.19 10.2 0.1 2.2 1 1 1 2 2 2 2 Tryptophan halogenase Pyr_redox_3 PF13738.1 KFH46337.1 - 0.0031 17.6 0.0 0.0053 16.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.2 KFH46337.1 - 0.0063 16.8 1.5 0.018 15.4 1.0 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Lycopene_cycl PF05834.7 KFH46337.1 - 0.023 13.5 0.3 0.039 12.8 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 KFH46337.1 - 0.16 10.7 0.4 0.25 10.1 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ESCRT-II PF05871.7 KFH46338.1 - 1.5e-45 154.4 0.0 2.1e-45 154.0 0.0 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit GHMP_kinases_C PF08544.8 KFH46338.1 - 0.18 11.9 0.8 0.45 10.7 0.5 1.7 1 1 0 1 1 1 0 GHMP kinases C terminal NRDE PF05742.7 KFH46339.1 - 5.1e-33 114.5 0.0 4.7e-32 111.3 0.0 2.0 1 1 0 1 1 1 1 NRDE protein zf-RING_2 PF13639.1 KFH46340.1 - 3.9e-10 39.3 6.0 6e-10 38.7 4.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFH46340.1 - 1.6e-08 34.5 1.9 2.6e-08 33.8 1.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KFH46340.1 - 1.7e-05 24.5 3.1 4e-05 23.3 2.1 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 KFH46340.1 - 0.0034 17.0 4.7 0.0075 15.9 3.1 1.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFH46340.1 - 0.0078 16.2 3.5 0.015 15.3 2.4 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFH46340.1 - 0.039 13.6 4.0 0.067 12.8 2.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KFH46340.1 - 0.057 13.0 2.5 0.099 12.2 0.3 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 KFH46340.1 - 0.17 11.6 2.6 0.34 10.6 1.8 1.5 1 1 0 1 1 1 0 zinc-RING finger domain DAO PF01266.19 KFH46341.1 - 1e-38 133.1 0.6 1.5e-38 132.6 0.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KFH46341.1 - 7.1e-06 25.8 0.1 0.012 15.3 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KFH46341.1 - 3.7e-05 23.6 0.0 0.00017 21.5 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KFH46341.1 - 0.00043 19.2 0.0 0.00095 18.1 0.0 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KFH46341.1 - 0.0074 15.1 0.1 3.3 6.4 0.0 2.7 3 0 0 3 3 3 2 FAD binding domain MFS_1 PF07690.11 KFH46342.1 - 5e-37 127.4 57.2 3.1e-36 124.8 39.3 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KFH46342.1 - 2.8e-13 48.9 24.1 1e-12 47.1 16.6 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KFH46342.1 - 0.00021 20.0 12.2 0.00021 20.0 8.5 3.8 2 2 1 3 3 3 1 Sugar (and other) transporter Hexokinase_2 PF03727.11 KFH46343.1 - 1.4e-32 112.8 0.0 2.9e-25 88.9 0.0 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 KFH46343.1 - 2e-24 86.1 0.0 1.1e-15 57.5 0.0 2.2 2 0 0 2 2 2 2 Hexokinase Methyltransf_16 PF10294.4 KFH46344.1 - 5.9e-25 87.7 0.0 1.4e-24 86.5 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KFH46344.1 - 0.0032 18.0 0.0 0.0066 17.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFH46344.1 - 0.019 14.3 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.7 KFH46344.1 - 0.063 13.7 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 KFH46344.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF2823 PF11034.3 KFH46345.1 - 5.4e-31 106.5 7.0 6.1e-31 106.3 4.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) P5CR_dimer PF14748.1 KFH46345.1 - 0.16 11.9 1.0 0.18 11.8 0.7 1.0 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation F-actin_cap_A PF01267.12 KFH46346.1 - 1.1e-85 286.9 0.0 6.2e-84 281.2 0.0 2.1 1 1 0 1 1 1 1 F-actin capping protein alpha subunit DUF2014 PF09427.5 KFH46347.1 - 1.7e-92 309.2 6.3 2.6e-92 308.6 4.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 KFH46347.1 - 1e-17 63.5 0.9 1e-17 63.5 0.6 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Nnf1 PF03980.9 KFH46347.1 - 0.015 15.2 1.5 0.015 15.2 1.1 2.0 2 0 0 2 2 2 0 Nnf1 Tom22 PF04281.8 KFH46347.1 - 0.22 11.0 2.1 0.76 9.3 1.4 1.9 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Abhydrolase_6 PF12697.2 KFH46349.1 - 6.4e-31 107.9 2.0 2.6e-30 106.0 0.5 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH46349.1 - 2.6e-05 24.0 0.0 0.00012 21.8 0.0 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFH46349.1 - 0.0041 16.7 0.0 0.01 15.4 0.0 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold PAF-AH_p_II PF03403.8 KFH46349.1 - 0.014 13.7 0.0 0.021 13.1 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II TFIIE_beta PF02186.10 KFH46350.1 - 1.1e-06 28.5 0.0 2.6e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 TFIIE beta subunit core domain Glyco_hydro_3 PF00933.16 KFH46351.1 - 2.7e-68 230.1 0.0 3.6e-68 229.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KFH46351.1 - 8.9e-54 182.4 0.1 1.4e-53 181.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KFH46351.1 - 3.8e-19 68.3 1.7 3.8e-19 68.3 1.2 1.9 2 0 0 2 2 2 1 Fibronectin type III-like domain Sugar-bind PF04198.8 KFH46351.1 - 0.015 14.2 0.1 0.073 11.9 0.0 2.0 2 0 0 2 2 2 0 Putative sugar-binding domain NAD_binding_10 PF13460.1 KFH46351.1 - 0.038 13.9 0.1 0.31 11.0 0.0 2.3 2 0 0 2 2 2 0 NADH(P)-binding WGG PF10273.4 KFH46352.1 - 4.1e-35 119.7 0.2 7.8e-35 118.8 0.1 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 P5CR_dimer PF14748.1 KFH46352.1 - 0.066 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation Nop25 PF09805.4 KFH46352.1 - 0.068 13.2 3.6 0.1 12.7 2.5 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) RRP7 PF12923.2 KFH46352.1 - 0.12 12.4 0.1 0.12 12.4 0.1 2.3 1 1 2 3 3 3 0 Ribosomal RNA-processing protein 7 (RRP7) WEMBL PF05701.6 KFH46353.1 - 0.017 13.6 17.0 0.026 13.0 11.8 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Cut8_M PF14483.1 KFH46353.1 - 0.018 14.8 3.9 0.27 11.0 0.0 3.0 3 0 0 3 3 3 0 Cut8 dimerisation domain DUF1664 PF07889.7 KFH46353.1 - 0.092 12.5 1.7 0.19 11.5 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF342 PF03961.8 KFH46353.1 - 9.3 4.5 6.3 16 3.7 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) zf-H2C2_2 PF13465.1 KFH46354.1 - 8e-07 29.0 0.8 8e-07 29.0 0.5 2.3 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 KFH46354.1 - 5.3e-06 26.4 14.5 7.6e-05 22.8 2.6 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFH46354.1 - 0.00019 21.5 11.5 0.00035 20.6 2.9 3.0 3 0 0 3 3 3 1 C2H2-type zinc finger PEMT PF04191.8 KFH46355.1 - 3.8e-31 107.3 3.2 7.2e-31 106.4 2.2 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase Steroid_dh PF02544.11 KFH46355.1 - 0.09 12.5 0.7 0.17 11.6 0.5 1.6 1 1 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase Thiolase_N PF00108.18 KFH46356.1 - 1.8e-72 243.5 0.8 2.5e-72 243.0 0.5 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KFH46356.1 - 1.2e-41 140.9 1.1 1.9e-41 140.3 0.2 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KFH46356.1 - 0.08 12.6 4.2 0.47 10.1 0.2 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 4HBT PF03061.17 KFH46357.1 - 8.5e-15 54.6 0.0 1e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 KFH46357.1 - 0.0038 16.9 0.0 0.004 16.9 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.1 KFH46357.1 - 0.052 13.5 0.0 0.064 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) SP_C-Propep PF08999.5 KFH46358.1 - 0.01 15.3 0.4 0.033 13.6 0.0 1.8 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide Arch_flagellin PF01917.11 KFH46358.1 - 0.025 14.2 0.4 0.031 13.8 0.3 1.1 1 0 0 1 1 1 0 Archaebacterial flagellin Shisa PF13908.1 KFH46358.1 - 0.065 13.4 0.0 0.077 13.1 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator CD99L2 PF12301.3 KFH46358.1 - 0.13 11.8 0.9 0.16 11.6 0.4 1.4 1 1 0 1 1 1 0 CD99 antigen like protein 2 DUF819 PF05684.7 KFH46358.1 - 0.25 10.1 4.1 0.32 9.7 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF819) GCM PF03615.10 KFH46360.1 - 0.16 11.5 0.1 0.22 11.1 0.1 1.1 1 0 0 1 1 1 0 GCM motif protein Ribosomal_S7 PF00177.16 KFH46361.1 - 2.3e-24 85.6 0.0 3.4e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e SchA_CurD PF04486.7 KFH46361.1 - 0.041 13.7 0.0 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 SchA/CurD like domain BSD PF03909.12 KFH46362.1 - 3.8e-17 61.7 0.1 8.1e-17 60.7 0.1 1.6 1 0 0 1 1 1 1 BSD domain RRM_1 PF00076.17 KFH46363.1 - 2.8e-83 273.5 7.7 1.6e-22 78.8 0.2 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH46363.1 - 3.7e-55 183.7 1.4 3.7e-16 58.8 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH46363.1 - 6.5e-41 137.9 0.1 1.9e-10 40.4 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 KFH46363.1 - 1.1e-25 89.0 2.3 5.2e-25 86.9 1.4 2.4 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 KFH46363.1 - 9.1e-06 25.3 0.0 3.2 7.6 0.0 5.0 5 0 0 5 5 5 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 KFH46363.1 - 0.00037 20.1 2.6 0.51 10.1 0.1 3.5 2 1 1 3 3 3 1 Limkain b1 TC1 PF15063.1 KFH46363.1 - 0.016 14.7 0.5 8.5 5.9 0.0 3.1 3 0 0 3 3 3 0 Thyroid cancer protein 1 OB_RNB PF08206.6 KFH46363.1 - 0.024 14.1 1.3 5.9 6.4 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain CbiG_mid PF11761.3 KFH46363.1 - 0.043 14.0 4.9 7.1 6.9 0.0 3.9 4 0 0 4 4 3 0 Cobalamin biosynthesis central region Nab6_mRNP_bdg PF10567.4 KFH46363.1 - 0.19 10.6 4.6 0.15 11.0 1.6 1.8 2 0 0 2 2 2 0 RNA-recognition motif CDC45 PF02724.9 KFH46363.1 - 0.41 8.6 13.2 0.6 8.0 9.1 1.2 1 0 0 1 1 1 0 CDC45-like protein F-box-like PF12937.2 KFH46364.1 - 0.00017 21.1 0.0 0.00039 20.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like Ceramidase_alk PF04734.8 KFH46365.1 - 6.2e-266 883.6 0.0 7e-266 883.4 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase Cellulase PF00150.13 KFH46366.1 - 4.6e-10 39.1 0.0 4.6e-10 39.1 0.0 1.7 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) EphA2_TM PF14575.1 KFH46366.1 - 0.00037 20.8 0.5 0.0011 19.3 0.0 2.1 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 KFH46366.1 - 0.082 13.0 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF2371 PF10177.4 KFH46366.1 - 0.13 12.1 0.7 0.4 10.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) Med13_C PF06333.7 KFH46367.1 - 1.7e-96 323.3 0.0 1.7e-96 323.3 0.0 1.6 2 0 0 2 2 2 1 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 KFH46367.1 - 7.6e-22 77.5 0.0 3.1e-21 75.5 0.0 2.0 2 0 0 2 2 2 1 Mediator complex subunit 13 N-terminal DUF1087 PF06465.8 KFH46367.1 - 1.2 9.1 3.8 2.3 8.2 0.1 2.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1087) UvrD_C PF13361.1 KFH46368.1 - 1.2e-77 261.7 0.1 1.7e-77 261.2 0.1 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 KFH46368.1 - 2e-67 227.7 0.1 1e-64 218.8 0.0 3.1 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 KFH46368.1 - 2.9e-14 53.0 0.0 1.4e-13 50.8 0.0 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 KFH46368.1 - 1e-12 47.5 1.3 1.1e-11 44.3 0.1 3.0 3 0 0 3 3 3 1 Part of AAA domain AAA_30 PF13604.1 KFH46368.1 - 2.2e-07 30.6 0.1 6.4e-05 22.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.1 KFH46368.1 - 9.9e-05 21.8 0.2 0.00094 18.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFH46368.1 - 0.00055 19.9 0.0 2.8 7.8 0.0 3.6 3 1 0 3 3 3 2 AAA ATPase domain Zeta_toxin PF06414.7 KFH46368.1 - 0.036 13.1 1.0 1.2 8.2 0.1 2.8 2 1 0 3 3 3 0 Zeta toxin ABC2_membrane PF01061.19 KFH46369.1 - 2e-81 272.1 55.8 1.1e-44 152.0 12.4 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KFH46369.1 - 2.4e-36 125.0 0.0 1.9e-17 63.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KFH46369.1 - 3e-28 97.5 0.3 2.9e-25 87.8 0.0 3.0 2 0 0 2 2 2 1 CDR ABC transporter ABC_trans_N PF14510.1 KFH46369.1 - 1.8e-08 34.3 0.1 6.8e-08 32.4 0.0 2.0 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_33 PF13671.1 KFH46369.1 - 7.3e-08 32.3 0.1 0.00072 19.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 KFH46369.1 - 1.4e-07 30.8 33.3 0.0001 21.4 7.0 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_17 PF13207.1 KFH46369.1 - 1.6e-07 32.1 0.0 0.0046 17.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KFH46369.1 - 2.4e-06 27.0 0.3 0.0037 16.6 0.0 3.1 4 0 0 4 4 3 2 AAA domain AAA_21 PF13304.1 KFH46369.1 - 2.3e-05 24.5 0.0 0.087 12.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KFH46369.1 - 2.4e-05 24.5 0.0 0.099 12.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 KFH46369.1 - 2.4e-05 23.8 1.0 0.0031 17.0 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 KFH46369.1 - 7.7e-05 22.1 0.1 0.0052 16.2 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KFH46369.1 - 0.00012 22.0 0.2 0.015 15.2 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 KFH46369.1 - 0.00029 21.1 0.0 0.081 13.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 KFH46369.1 - 0.00031 20.3 0.8 0.88 9.2 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 KFH46369.1 - 0.00044 19.4 0.0 0.0025 17.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_28 PF13521.1 KFH46369.1 - 0.00052 20.0 0.0 0.022 14.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KFH46369.1 - 0.0019 17.8 0.3 2.1 7.9 0.0 2.4 2 0 0 2 2 2 2 NACHT domain SMC_N PF02463.14 KFH46369.1 - 0.0039 16.4 0.0 0.65 9.1 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_19 PF13245.1 KFH46369.1 - 0.011 15.4 0.9 3.8 7.3 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 KFH46369.1 - 0.012 15.1 0.1 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family PduV-EutP PF10662.4 KFH46369.1 - 0.024 14.1 0.5 2.2 7.7 0.1 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 KFH46369.1 - 0.03 13.7 0.1 1.3 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain Miro PF08477.8 KFH46369.1 - 0.041 14.3 0.0 6.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA PF00004.24 KFH46369.1 - 0.066 13.4 0.0 17 5.6 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KFH46369.1 - 0.071 13.2 0.1 7.7 6.7 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.1 KFH46369.1 - 0.097 12.9 0.4 0.74 10.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.1 KFH46369.1 - 0.11 12.0 0.1 13 5.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 KFH46369.1 - 0.32 10.0 0.0 2.6 6.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Gryzun PF07919.7 KFH46370.1 - 2.1e-95 320.1 0.0 2.7e-95 319.7 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 KFH46370.1 - 8.8e-76 254.6 0.7 3.4e-73 246.1 0.6 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.2 KFH46370.1 - 0.00047 19.9 0.0 0.001 18.8 0.0 1.6 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking Surp PF01805.15 KFH46371.1 - 5.2e-14 51.6 0.0 9.4e-14 50.8 0.0 1.5 1 0 0 1 1 1 1 Surp module Fungal_trans PF04082.13 KFH46372.1 - 4.2e-08 32.3 1.2 2.8e-07 29.6 0.9 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 KFH46372.1 - 7.4e-08 32.1 9.5 0.0012 19.0 2.6 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KFH46372.1 - 2.6e-07 30.5 13.8 0.0013 18.9 0.2 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFH46372.1 - 5.4e-07 29.6 16.6 8e-06 25.8 1.5 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFH46372.1 - 0.056 13.6 0.9 0.79 9.9 0.6 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Glucosamine_iso PF01182.15 KFH46373.1 - 4.7e-25 88.4 0.0 7.2e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Abhydrolase_3 PF07859.8 KFH46374.1 - 9.1e-40 136.4 0.1 1.3e-30 106.5 0.1 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 KFH46374.1 - 3.5e-11 42.3 0.0 3.8e-10 38.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) COesterase PF00135.23 KFH46374.1 - 0.00031 19.6 0.5 0.046 12.4 0.1 2.2 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_5 PF12695.2 KFH46374.1 - 0.00089 19.0 0.0 0.0036 17.0 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family NAD_binding_10 PF13460.1 KFH46375.1 - 3e-12 46.9 0.6 3.7e-12 46.6 0.4 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFH46375.1 - 8.8e-08 31.8 0.0 1.5e-07 31.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KFH46375.1 - 6.2e-05 22.3 0.0 9.7e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family DUF1471 PF07338.8 KFH46375.1 - 0.0082 15.7 1.4 0.021 14.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1471) Semialdhyde_dh PF01118.19 KFH46375.1 - 0.012 15.9 0.0 0.026 14.8 0.0 1.8 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 KFH46375.1 - 0.012 14.5 0.1 2 7.2 0.0 2.7 1 1 2 3 3 3 0 Male sterility protein Amidohydro_4 PF13147.1 KFH46377.1 - 4.7e-14 53.0 0.0 8.3e-07 29.3 0.0 2.7 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 KFH46377.1 - 2.5e-08 33.5 0.1 7.4e-08 32.0 0.1 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 KFH46377.1 - 2e-06 27.6 0.0 2e-05 24.4 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KFH46377.1 - 0.00014 21.5 0.0 0.00052 19.7 0.0 1.9 2 0 0 2 2 2 1 Amidohydrolase Flavokinase PF01687.12 KFH46378.1 - 3.1e-33 114.3 0.0 2.1e-32 111.6 0.0 1.9 1 1 0 1 1 1 1 Riboflavin kinase PAS PF00989.19 KFH46379.1 - 0.00047 19.9 0.0 0.002 17.8 0.0 2.0 2 0 0 2 2 2 1 PAS fold Zn_clus PF00172.13 KFH46379.1 - 0.0028 17.5 8.6 0.0028 17.5 5.9 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_9 PF13426.1 KFH46379.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 PAS domain DUF1237 PF06824.6 KFH46380.1 - 8.1e-168 558.4 0.0 9.3e-168 558.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) NIR_SIR PF01077.17 KFH46381.1 - 3e-30 104.6 0.1 9.1e-30 103.0 0.0 1.9 2 0 0 2 2 2 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 KFH46381.1 - 2.3e-26 92.9 0.1 4e-26 92.1 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFH46381.1 - 8.3e-16 58.1 2.1 1.6e-13 50.8 0.2 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 KFH46381.1 - 3.3e-14 52.4 0.0 3.7e-13 49.0 0.0 2.6 2 1 0 2 2 2 1 Rieske-like [2Fe-2S] domain Fer2_BFD PF04324.10 KFH46381.1 - 6.6e-12 45.2 5.2 4.7e-11 42.5 2.0 2.8 3 0 0 3 3 2 1 BFD-like [2Fe-2S] binding domain Rieske PF00355.21 KFH46381.1 - 1.3e-10 40.7 0.1 4.2e-10 39.0 0.0 1.9 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.12 KFH46381.1 - 6.7e-09 35.2 0.0 1.4e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox_3 PF13738.1 KFH46381.1 - 4.1e-07 30.2 0.1 7.7e-05 22.8 0.1 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFH46381.1 - 0.029 14.1 3.0 10 5.8 0.0 3.6 4 0 0 4 4 4 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KFH46381.1 - 0.07 13.1 0.1 19 5.3 0.0 2.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 KFH46381.1 - 0.081 13.1 0.2 1.4 9.2 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.17 KFH46381.1 - 0.51 9.1 1.5 20 3.8 0.1 2.9 2 1 1 3 3 3 0 Glucose inhibited division protein A BAF1_ABF1 PF04684.8 KFH46382.1 - 0.027 13.3 0.7 0.033 13.0 0.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TBP PF00352.16 KFH46383.1 - 2.8e-70 231.7 0.1 4.2e-35 118.9 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 KFH46383.1 - 0.0002 21.3 0.0 0.82 9.7 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Pollen_allerg_2 PF01620.11 KFH46383.1 - 0.0045 17.3 0.3 0.0061 16.8 0.2 1.3 1 0 0 1 1 1 1 Ribonuclease (pollen allergen) PTCB-BRCT PF12738.2 KFH46385.1 - 4e-26 90.6 0.4 2.6e-18 65.6 0.1 4.3 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.21 KFH46385.1 - 7.7e-24 83.6 0.0 2.5e-08 33.9 0.0 5.9 6 0 0 6 6 6 3 BRCA1 C Terminus (BRCT) domain MRP-L27 PF09809.4 KFH46386.1 - 8.3e-06 25.3 0.2 1.1e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Cyt-b5 PF00173.23 KFH46388.1 - 3.5e-26 90.8 0.3 4.5e-26 90.4 0.2 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_hydro_31 PF01055.21 KFH46390.1 - 6.4e-114 381.1 0.3 7.9e-114 380.8 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KFH46390.1 - 8e-18 64.0 0.1 4.3e-17 61.7 0.1 2.4 1 0 0 1 1 1 1 Galactose mutarotase-like Coat_F PF07875.7 KFH46390.1 - 0.097 12.8 0.0 0.86 9.7 0.0 2.2 2 0 0 2 2 2 0 Coat F domain Aminotran_1_2 PF00155.16 KFH46391.1 - 3.1e-38 131.6 0.0 4e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Piwi PF02171.12 KFH46392.1 - 2.8e-68 230.0 0.0 4.2e-68 229.5 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 KFH46392.1 - 3.6e-08 32.6 0.1 1.3e-07 30.8 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) PAZ PF02170.17 KFH46392.1 - 7e-07 28.6 0.0 1.2e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 PAZ domain HEAT PF02985.17 KFH46392.1 - 0.023 14.7 0.2 0.15 12.2 0.0 2.4 3 0 0 3 3 3 0 HEAT repeat DSBA PF01323.15 KFH46393.1 - 4.4e-22 78.5 0.0 5.3e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.1 KFH46393.1 - 0.13 12.1 0.0 10 6.0 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin domain PLDc_2 PF13091.1 KFH46394.1 - 1.1e-17 63.9 0.0 1.7e-09 37.4 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KFH46394.1 - 1.7e-05 24.4 0.0 0.0072 16.1 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.3 KFH46394.1 - 0.028 13.3 0.0 0.09 11.7 0.0 1.8 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB VHS PF00790.14 KFH46395.1 - 2.4e-21 75.8 0.0 6.3e-21 74.4 0.0 1.7 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 KFH46395.1 - 1.6e-11 44.0 2.9 3.4e-11 43.0 2.0 1.5 1 0 0 1 1 1 1 GAT domain Translin PF01997.11 KFH46395.1 - 0.14 11.6 4.9 0.034 13.7 1.0 1.7 2 0 0 2 2 2 0 Translin family SR-25 PF10500.4 KFH46395.1 - 0.31 10.4 19.3 0.58 9.5 13.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein COX16 PF14138.1 KFH46395.1 - 2.2 8.5 5.3 2.2 8.4 0.1 2.8 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Peptidase_M16_C PF05193.16 KFH46395.1 - 5.1 6.7 5.9 39 3.8 0.1 3.2 2 1 0 3 3 3 0 Peptidase M16 inactive domain CDC27 PF09507.5 KFH46395.1 - 8.6 5.4 24.6 0.61 9.2 9.5 2.3 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Amastin PF07344.6 KFH46396.1 - 1 8.9 12.0 0.24 11.0 0.4 2.3 2 0 0 2 2 2 0 Amastin surface glycoprotein Polysacc_synt_3 PF13440.1 KFH46396.1 - 4.2 6.7 15.0 0.39 10.1 1.3 3.3 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein RXT2_N PF08595.6 KFH46397.1 - 2.4e-38 131.2 0.0 2.4e-38 131.2 0.0 2.5 3 0 0 3 3 3 1 RXT2-like, N-terminal ATP-synt_8 PF00895.15 KFH46398.1 - 0.064 13.4 0.5 0.064 13.4 0.3 2.1 2 0 0 2 2 2 0 ATP synthase protein 8 PRiA4_ORF3 PF07929.6 KFH46398.1 - 0.08 12.3 0.1 0.18 11.1 0.1 1.5 1 0 0 1 1 1 0 Plasmid pRiA4b ORF-3-like protein Tfb2 PF03849.9 KFH46399.1 - 3.6e-133 443.7 0.0 4.5e-133 443.4 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 KFH46399.1 - 0.00014 21.6 0.0 0.00037 20.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain NUC153 PF08159.7 KFH46400.1 - 4.4e-14 51.7 1.6 1e-13 50.6 1.1 1.7 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 KFH46400.1 - 0.0017 18.2 0.5 0.35 10.8 0.0 3.6 4 0 0 4 4 4 1 WD domain, G-beta repeat Usp PF00582.21 KFH46401.1 - 8.1e-21 74.6 7.0 2.8e-20 72.9 2.0 2.8 2 1 0 2 2 2 1 Universal stress protein family DUF3632 PF12311.3 KFH46402.1 - 2e-37 128.8 3.8 2.9e-37 128.2 2.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) APH PF01636.18 KFH46402.1 - 1.7e-08 34.5 0.0 4.3e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family 3A PF00803.13 KFH46402.1 - 0.09 11.8 0.0 0.66 9.0 0.0 2.0 2 0 0 2 2 2 0 3A/RNA2 movement protein family Nop14 PF04147.7 KFH46404.1 - 0.012 13.5 32.7 0.016 13.1 22.6 1.0 1 0 0 1 1 1 0 Nop14-like family CDC27 PF09507.5 KFH46404.1 - 0.14 11.3 24.5 0.21 10.7 17.0 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Daxx PF03344.10 KFH46404.1 - 0.75 8.2 33.1 1.1 7.6 22.9 1.2 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 KFH46404.1 - 1.8 7.7 35.8 2.4 7.3 24.8 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.5 KFH46404.1 - 4.3 6.3 32.7 5.7 5.9 22.7 1.1 1 0 0 1 1 1 0 BUD22 DUF1510 PF07423.6 KFH46404.1 - 9.5 5.5 27.7 14 4.9 19.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) C2 PF00168.25 KFH46405.1 - 7.1e-19 67.4 0.0 2.4e-11 43.3 0.0 2.7 2 0 0 2 2 2 2 C2 domain SLS PF14611.1 KFH46406.1 - 0.015 14.6 0.4 0.032 13.6 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator TFIIA PF03153.8 KFH46406.1 - 2.1 8.1 8.2 2.9 7.7 5.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nucleo_P87 PF07267.6 KFH46406.1 - 6.4 5.3 5.6 6.5 5.3 0.0 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 UQ_con PF00179.21 KFH46408.1 - 8.1e-50 167.9 0.0 9.7e-50 167.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFH46408.1 - 5.6e-05 22.9 0.0 7.2e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFH46408.1 - 0.00062 19.6 0.1 0.0012 18.7 0.1 1.5 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 KFH46408.1 - 0.0027 17.3 0.0 0.0038 16.8 0.0 1.4 1 0 0 1 1 1 1 UEV domain Glyco_transf_28 PF03033.15 KFH46409.1 - 2.1e-20 72.9 0.1 1.9e-19 69.8 0.0 2.4 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KFH46409.1 - 1.8e-05 23.5 0.0 2.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KFH46409.1 - 0.0011 18.6 0.4 0.005 16.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain UIM PF02809.15 KFH46409.1 - 0.21 11.2 23.5 0.8 9.4 1.7 4.9 4 0 0 4 4 4 0 Ubiquitin interaction motif Rep_4 PF05797.6 KFH46409.1 - 1.8 7.1 4.4 3.3 6.3 3.1 1.3 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) Methyltransf_31 PF13847.1 KFH46410.1 - 1.6e-14 53.7 0.0 2.2e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH46410.1 - 1.3e-13 51.1 0.1 4.3e-13 49.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH46410.1 - 1.5e-10 41.4 0.0 3e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH46410.1 - 1.9e-09 38.0 0.0 3.9e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH46410.1 - 4.2e-09 36.3 0.0 7.8e-09 35.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFH46410.1 - 4.6e-08 33.3 0.0 8.1e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFH46410.1 - 3.4e-07 30.2 0.3 7.6e-07 29.1 0.1 1.7 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 KFH46410.1 - 1.3e-06 27.8 0.0 2.2e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 KFH46410.1 - 4.9e-06 26.2 0.0 7.8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.6 KFH46410.1 - 0.00012 20.8 0.0 0.00016 20.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.8 KFH46410.1 - 0.00047 19.3 0.0 0.00062 18.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.15 KFH46410.1 - 0.002 17.1 0.0 0.0028 16.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase CMAS PF02353.15 KFH46410.1 - 0.004 16.2 0.0 0.006 15.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 KFH46410.1 - 0.005 16.5 0.0 0.0072 16.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 KFH46410.1 - 0.005 16.4 0.0 0.0091 15.5 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.13 KFH46410.1 - 0.0054 15.8 0.0 0.022 13.8 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MRF_C1 PF13887.1 KFH46410.1 - 0.015 14.2 0.2 0.97 8.5 0.0 2.3 2 0 0 2 2 2 0 Myelin gene regulatory factor -C-terminal domain 1 M20_dimer PF07687.9 KFH46410.1 - 0.055 13.2 0.2 0.27 10.9 0.1 2.2 1 1 0 1 1 1 0 Peptidase dimerisation domain zf-Apc11 PF12861.2 KFH46411.1 - 2.7e-45 152.1 12.0 3.2e-45 151.9 8.3 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 KFH46411.1 - 1.8e-32 111.2 11.3 2.2e-32 111.0 7.9 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KFH46411.1 - 1.4e-08 34.4 18.4 1.8e-07 30.8 12.7 2.5 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 KFH46411.1 - 5.5e-05 22.9 2.0 5.5e-05 22.9 1.4 2.3 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KFH46411.1 - 6.8e-05 22.4 14.1 0.00026 20.5 9.8 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFH46411.1 - 7e-05 22.4 13.1 0.0033 17.0 9.0 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFH46411.1 - 0.00013 21.9 13.5 0.0015 18.5 9.3 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KFH46411.1 - 0.00084 18.8 13.1 0.0011 18.5 2.1 2.3 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 KFH46411.1 - 0.0019 18.1 15.4 0.027 14.4 10.7 2.8 1 1 0 1 1 1 1 FANCL C-terminal domain zf-HIT PF04438.11 KFH46411.1 - 0.0083 15.7 3.0 0.021 14.4 0.6 2.3 2 0 0 2 2 2 1 HIT zinc finger zf-Nse PF11789.3 KFH46411.1 - 0.011 15.2 5.4 0.018 14.5 3.7 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.1 KFH46411.1 - 0.014 15.0 16.0 0.3 10.8 11.4 2.4 1 1 1 2 2 2 0 zinc-RING finger domain DUF2256 PF10013.4 KFH46411.1 - 0.18 11.5 0.3 0.18 11.5 0.2 3.6 2 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-met2 PF12907.2 KFH46411.1 - 0.38 10.7 0.2 0.38 10.7 0.1 2.7 3 0 0 3 3 3 0 Zinc-binding Opy2 PF09463.5 KFH46411.1 - 0.48 10.5 11.1 1.9 8.6 4.5 2.2 2 0 0 2 2 2 0 Opy2 protein zf-RING-like PF08746.6 KFH46411.1 - 0.51 10.3 14.2 3 7.9 9.8 2.2 1 1 0 1 1 1 0 RING-like domain zf-RING_UBOX PF13445.1 KFH46411.1 - 1.2 8.9 8.0 4.8 6.9 5.5 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zinc-ribbons_6 PF07191.7 KFH46411.1 - 1.3 8.8 9.9 1.2 8.9 0.1 2.6 1 1 0 2 2 2 0 zinc-ribbons DUF329 PF03884.9 KFH46411.1 - 2.3 7.8 8.4 0.71 9.4 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF329) zf-HC5HC2H PF13771.1 KFH46411.1 - 4.4 7.5 11.7 2.5 8.2 4.4 2.4 1 1 1 2 2 2 0 PHD-like zinc-binding domain PHD PF00628.24 KFH46411.1 - 4.6 7.0 14.5 21 4.9 10.0 2.0 1 1 0 1 1 1 0 PHD-finger zf-HC5HC2H_2 PF13832.1 KFH46411.1 - 5.1 7.1 11.1 2.2 8.2 4.1 2.2 1 1 1 2 2 2 0 PHD-zinc-finger like domain RINGv PF12906.2 KFH46411.1 - 5.8 7.0 14.6 8.4 6.5 8.8 2.2 1 1 1 2 2 2 0 RING-variant domain DZR PF12773.2 KFH46411.1 - 7.3 6.4 13.5 4.6e+02 0.7 9.4 2.2 1 1 0 1 1 1 0 Double zinc ribbon Asp PF00026.18 KFH46412.1 - 5.7e-58 196.6 0.0 7e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFH46412.1 - 2.2e-07 30.9 0.0 1.9e-05 24.7 0.0 3.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KFH46412.1 - 0.00027 20.5 0.0 0.00067 19.2 0.0 1.7 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KFH46412.1 - 0.0062 17.0 0.1 8 7.0 0.0 3.1 3 0 0 3 3 3 2 Aspartyl protease NIF PF03031.13 KFH46413.1 - 7.3e-51 171.9 0.1 9.6e-51 171.5 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 KFH46413.1 - 0.1 12.7 0.1 1.1 9.4 0.0 2.0 1 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KFH46414.1 - 3.7e-54 183.1 0.2 8.3e-54 182.0 0.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KFH46414.1 - 3.3e-44 151.8 4.3 3.3e-44 151.8 3.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KFH46414.1 - 8e-44 147.6 0.1 1.4e-11 44.3 0.1 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 KFH46414.1 - 1.4e-12 48.1 0.0 6.3e-12 46.0 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFH46414.1 - 5.5e-06 26.1 1.3 3.4e-05 23.5 0.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PRA1 PF03208.14 KFH46414.1 - 0.74 9.1 5.4 0.2 10.9 0.2 2.4 2 0 0 2 2 2 0 PRA1 family protein Rho_N PF07498.7 KFH46416.1 - 0.11 12.2 0.3 0.17 11.6 0.2 1.2 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain RGS PF00615.14 KFH46417.1 - 1.8e-10 40.9 0.0 7.8e-09 35.6 0.0 2.3 1 1 0 1 1 1 1 Regulator of G protein signaling domain Ribosomal_S8 PF00410.14 KFH46418.1 - 2.4e-23 82.3 0.0 3e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Aldo_ket_red PF00248.16 KFH46419.1 - 5.7e-52 176.2 0.0 6.5e-52 176.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1776 PF08643.5 KFH46420.1 - 1.2e-104 349.6 0.0 1.4e-104 349.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Cation_efflux PF01545.16 KFH46421.1 - 8.4e-78 261.3 1.9 3.1e-77 259.4 1.3 1.7 1 1 0 1 1 1 1 Cation efflux family NDUF_C2 PF06374.6 KFH46421.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) Memo PF01875.12 KFH46423.1 - 6.1e-69 231.9 0.0 7e-69 231.7 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Fungal_trans PF04082.13 KFH46424.1 - 3e-18 65.6 0.2 5e-18 64.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH46424.1 - 2e-05 24.3 7.9 3.5e-05 23.6 5.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPT PF03151.11 KFH46425.1 - 7.4e-22 77.6 7.5 7.4e-22 77.6 5.2 2.2 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KFH46425.1 - 5.1e-07 28.9 17.9 7.7e-07 28.3 12.4 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KFH46425.1 - 4.4 7.3 34.9 1.4 8.9 5.6 2.9 2 1 0 2 2 2 0 EamA-like transporter family Aldose_epim PF01263.15 KFH46427.1 - 1.3e-40 139.3 0.0 1.5e-40 139.1 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase WD40 PF00400.27 KFH46428.1 - 1.1e-42 142.4 9.5 4.4e-10 39.0 0.1 7.4 7 1 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KFH46428.1 - 0.011 15.4 1.5 1.1 8.9 0.1 3.1 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A Methyltransf_23 PF13489.1 KFH46429.1 - 1.7e-14 53.8 0.0 3.4e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH46429.1 - 0.00024 21.5 0.0 0.0013 19.1 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH46429.1 - 0.0011 19.5 0.2 0.014 15.9 0.1 2.7 2 1 0 2 2 2 1 Methyltransferase domain IP_trans PF02121.13 KFH46429.1 - 0.0031 16.7 0.0 0.015 14.5 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol transfer protein Methyltransf_11 PF08241.7 KFH46429.1 - 0.0049 17.3 0.0 0.044 14.2 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH46429.1 - 0.015 14.9 0.0 0.91 9.1 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain HemN_C PF06969.11 KFH46429.1 - 0.077 13.0 0.1 0.96 9.5 0.0 2.5 2 0 0 2 2 2 0 HemN C-terminal domain Imm45 PF15603.1 KFH46429.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 45 Rif1_N PF12231.3 KFH46430.1 - 1.5e-132 442.0 0.6 2.2e-132 441.5 0.4 1.3 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Flavodoxin_1 PF00258.20 KFH46431.1 - 2.9e-10 40.3 0.0 4.2e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin FMN_red PF03358.10 KFH46431.1 - 8.3e-10 38.3 0.0 1.5e-09 37.5 0.0 1.5 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 KFH46431.1 - 2.8e-07 30.2 0.0 3.5e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 KFH46431.1 - 0.15 12.0 0.0 7.5 6.5 0.0 2.2 2 0 0 2 2 2 0 Flavodoxin domain Acetyltransf_3 PF13302.1 KFH46433.1 - 8e-36 123.3 0.0 1.1e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain F-box-like PF12937.2 KFH46434.1 - 0.051 13.3 0.0 0.051 13.3 0.0 2.2 2 0 0 2 2 2 0 F-box-like Ribosomal_L18ae PF01775.12 KFH46435.1 - 1.5e-58 196.0 0.5 1.9e-58 195.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain DUF155 PF02582.9 KFH46436.1 - 1.1e-58 198.0 0.1 1.6e-58 197.4 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Cyclin_N PF00134.18 KFH46438.1 - 7.6e-37 125.7 0.1 1.4e-36 124.8 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFH46438.1 - 5.2e-11 42.5 1.0 9.3e-11 41.6 0.1 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain BTB PF00651.26 KFH46439.1 - 3.4e-08 33.4 0.1 1.3e-07 31.5 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Ribosomal_60s PF00428.14 KFH46440.1 - 0.032 14.6 0.9 0.035 14.4 0.6 1.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein zf-C4H2 PF10146.4 KFH46440.1 - 0.082 12.9 2.8 0.078 12.9 1.9 1.0 1 0 0 1 1 1 0 Zinc finger-containing protein TrkH PF02386.11 KFH46442.1 - 6.1e-93 311.2 0.4 4.3e-88 295.2 0.0 2.2 2 0 0 2 2 2 2 Cation transport protein Sulfatase PF00884.18 KFH46443.1 - 3.4e-58 197.2 0.1 4.6e-58 196.8 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 KFH46443.1 - 8.5e-21 73.5 0.4 8.5e-21 73.5 0.3 2.5 2 1 1 3 3 3 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 KFH46443.1 - 1.2e-10 41.2 0.5 2.6e-08 33.6 0.3 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KFH46443.1 - 9.9e-06 24.2 0.0 1.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF1501 PF07394.7 KFH46443.1 - 0.012 14.4 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Sulfatase_C PF14707.1 KFH46443.1 - 0.019 15.2 0.1 0.053 13.8 0.0 1.8 2 0 0 2 2 2 0 C-terminal region of aryl-sulfatase GFA PF04828.9 KFH46445.1 - 4.6e-13 48.9 3.2 1.1e-12 47.7 2.2 1.6 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-RING_5 PF14634.1 KFH46445.1 - 0.11 12.2 3.0 0.35 10.6 2.1 1.8 1 1 0 1 1 1 0 zinc-RING finger domain Cys_rich_CWC PF14375.1 KFH46445.1 - 1.2 9.0 8.1 0.12 12.3 1.9 2.0 2 0 0 2 2 2 0 Cysteine-rich CWC Ribosomal_L37e PF01907.14 KFH46445.1 - 1.6 8.6 5.0 0.3 10.9 0.6 1.9 2 0 0 2 2 2 0 Ribosomal protein L37e Glyco_transf_90 PF05686.7 KFH46446.1 - 0.0003 19.5 0.3 0.51 8.9 0.0 3.8 3 2 0 3 3 3 2 Glycosyl transferase family 90 Neuromodulin PF06614.6 KFH46447.1 - 0.076 12.9 9.6 0.094 12.6 6.7 1.1 1 0 0 1 1 1 0 Neuromodulin DUF4349 PF14257.1 KFH46447.1 - 0.12 11.6 6.2 0.15 11.2 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) RNase_P_p30 PF01876.11 KFH46448.1 - 3.2e-44 149.7 0.0 4.7e-44 149.2 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 FAD_binding_8 PF08022.7 KFH46449.1 - 2.7e-23 81.8 0.0 6.2e-23 80.6 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KFH46449.1 - 1.7e-21 76.7 0.0 2.7e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KFH46449.1 - 2.5e-18 66.3 10.5 2.5e-18 66.3 7.3 2.1 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KFH46449.1 - 2e-05 24.6 0.0 4.5e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain BRCT PF00533.21 KFH46450.1 - 0.02 15.0 0.0 0.059 13.5 0.0 1.9 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Sec61_beta PF03911.11 KFH46451.1 - 1.5e-19 69.4 2.2 2e-19 69.0 1.5 1.2 1 0 0 1 1 1 1 Sec61beta family NrfD PF03916.9 KFH46452.1 - 0.18 11.2 5.6 0.067 12.5 1.2 1.7 1 1 1 2 2 2 0 Polysulphide reductase, NrfD Pkinase PF00069.20 KFH46453.1 - 5.3e-62 209.3 0.0 6.8e-62 208.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH46453.1 - 1.6e-29 102.7 0.0 2.3e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH46453.1 - 6.9e-05 21.9 0.0 9.2e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFH46453.1 - 0.0089 15.7 0.0 0.48 10.1 0.0 2.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KFH46453.1 - 0.0091 15.0 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ABC_membrane_2 PF06472.10 KFH46454.1 - 1.4e-94 316.3 0.0 1.4e-93 313.1 0.0 2.2 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KFH46454.1 - 7.2e-17 61.9 0.0 1.6e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KFH46454.1 - 0.0029 17.6 0.0 0.0089 16.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFH46454.1 - 0.025 14.5 0.1 0.063 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.16 KFH46454.1 - 0.042 13.0 0.1 0.075 12.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 KFH46454.1 - 0.043 14.6 0.0 0.16 12.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KFH46454.1 - 0.044 13.3 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.21 KFH46454.1 - 0.058 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 KFH46454.1 - 0.097 12.7 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.1 KFH46454.1 - 0.12 12.5 0.0 0.27 11.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KFH46454.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 KFH46454.1 - 1.2 9.3 6.4 13 5.9 2.9 2.7 2 1 0 2 2 2 0 AAA domain Amidase PF01425.16 KFH46455.1 - 3.9e-90 302.8 0.0 5.6e-90 302.3 0.0 1.2 1 0 0 1 1 1 1 Amidase Rhodanese PF00581.15 KFH46456.1 - 1.2e-21 77.1 0.0 1e-13 51.6 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain Glyco_hydro_18 PF00704.23 KFH46457.1 - 6.5e-61 206.6 0.0 8e-61 206.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 RuBisCO_large PF00016.15 KFH46457.1 - 0.0027 16.6 0.1 0.031 13.1 0.1 2.1 2 0 0 2 2 2 1 Ribulose bisphosphate carboxylase large chain, catalytic domain GTP_EFTU PF00009.22 KFH46458.1 - 1.5e-55 187.5 0.2 2.8e-55 186.7 0.2 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 KFH46458.1 - 1.8e-31 107.8 0.0 3.4e-31 106.8 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 KFH46458.1 - 6.1e-30 103.2 0.0 1.8e-29 101.6 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 KFH46458.1 - 1.2e-21 76.4 0.0 3e-21 75.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KFH46458.1 - 3.2e-13 49.5 0.0 7.5e-13 48.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 DUF442 PF04273.8 KFH46458.1 - 0.09 12.6 0.0 2.1 8.2 0.0 2.7 2 0 0 2 2 2 0 Putative phosphatase (DUF442) Pkinase_Tyr PF07714.12 KFH46459.1 - 1.2e-05 24.4 0.1 0.0021 17.1 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 KFH46459.1 - 0.00028 20.1 0.0 0.0016 17.6 0.0 2.1 2 1 1 3 3 3 1 Protein kinase domain PCI PF01399.22 KFH46460.1 - 9.2e-07 29.1 0.0 1.7e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 PCI domain zf-C2H2_4 PF13894.1 KFH46461.1 - 3.8e-06 26.8 17.0 0.068 13.5 0.3 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KFH46461.1 - 0.00016 21.7 14.8 0.23 11.8 1.3 4.1 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 KFH46461.1 - 2.1 8.7 9.9 47 4.4 0.1 4.1 3 0 0 3 3 3 0 C2H2-type zinc-finger domain LRR_4 PF12799.2 KFH46462.1 - 3.9e-44 147.6 32.2 1.9e-12 46.5 0.6 7.0 4 2 4 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFH46462.1 - 3.5e-26 90.7 53.5 3.6e-08 33.0 0.4 5.1 1 1 7 8 8 8 7 Leucine rich repeat LRR_1 PF00560.28 KFH46462.1 - 2.8e-11 41.8 24.3 0.19 11.9 0.4 10.2 12 0 0 12 12 12 4 Leucine Rich Repeat LRR_9 PF14580.1 KFH46462.1 - 3.6e-11 42.9 10.1 5.4e-05 22.8 0.7 3.8 1 1 3 4 4 4 4 Leucine-rich repeat LRR_7 PF13504.1 KFH46462.1 - 1.9e-10 39.1 12.7 2.6 8.6 0.0 8.6 8 0 0 8 8 8 3 Leucine rich repeat LRR_6 PF13516.1 KFH46462.1 - 3.1e-10 39.0 21.1 0.065 13.3 0.3 9.9 7 3 3 10 10 10 3 Leucine Rich repeat YARHG PF13308.1 KFH46462.1 - 0.092 12.3 1.5 1.4 8.5 0.0 2.8 3 0 0 3 3 3 0 YARHG domain Ribosomal_L31e PF01198.14 KFH46463.1 - 9.3e-38 127.7 2.0 1.2e-37 127.4 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e MS_channel PF00924.13 KFH46463.1 - 0.053 12.8 0.1 0.062 12.6 0.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel FAD_binding_3 PF01494.14 KFH46464.1 - 4.1e-16 58.9 0.0 1.1e-15 57.5 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KFH46464.1 - 2.5e-05 24.2 0.0 6.8e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFH46464.1 - 0.00032 19.6 0.0 0.00067 18.6 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFH46464.1 - 0.00047 20.5 0.0 0.0051 17.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KFH46464.1 - 0.00049 19.0 0.0 0.00086 18.2 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KFH46464.1 - 0.00062 19.7 0.0 0.0014 18.5 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFH46464.1 - 0.0025 16.3 0.0 0.0035 15.8 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein SE PF08491.5 KFH46464.1 - 0.016 14.0 0.0 0.032 13.0 0.0 1.5 1 0 0 1 1 1 0 Squalene epoxidase FAD_oxidored PF12831.2 KFH46464.1 - 0.019 14.0 0.0 0.09 11.8 0.0 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KFH46464.1 - 0.06 12.9 0.0 0.092 12.3 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 KFH46464.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Thi4 family zf-CCCH PF00642.19 KFH46465.1 - 8.4e-26 89.1 33.4 2.8e-08 33.2 0.3 5.3 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) API5 PF05918.6 KFH46465.1 - 0.014 13.8 6.6 0.016 13.7 4.6 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) zf-CCCH_2 PF14608.1 KFH46465.1 - 0.022 14.7 33.6 0.023 14.6 0.5 5.8 5 1 0 5 5 5 0 Zinc finger C-x8-C-x5-C-x3-H type DUF4637 PF15470.1 KFH46465.1 - 0.036 13.6 2.0 0.065 12.8 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) GRP PF07172.6 KFH46465.1 - 3.9 8.0 17.5 1.3 9.4 9.0 2.0 2 0 0 2 2 2 0 Glycine rich protein family Iso_dh PF00180.15 KFH46466.1 - 1.3e-97 326.8 0.0 2.1e-97 326.2 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Sugar_tr PF00083.19 KFH46467.1 - 1.8e-110 369.6 14.9 2.1e-110 369.4 10.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH46467.1 - 6.1e-20 71.2 26.1 1.6e-13 50.0 2.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 KFH46467.1 - 0.022 12.8 0.9 0.042 11.8 0.6 1.5 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Arginase PF00491.16 KFH46468.1 - 5.2e-66 222.7 0.0 9.1e-66 221.9 0.0 1.4 1 1 0 1 1 1 1 Arginase family HATPase_c PF02518.21 KFH46470.1 - 6.5e-29 99.8 0.1 1.4e-28 98.7 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KFH46470.1 - 5e-23 81.2 0.0 9.9e-23 80.2 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 KFH46470.1 - 2.3e-22 79.3 0.0 7.2e-12 45.6 0.0 4.5 4 0 0 4 4 4 3 PAS domain HisKA PF00512.20 KFH46470.1 - 2.4e-21 75.4 0.0 7.8e-21 73.8 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 KFH46470.1 - 7.6e-19 67.5 0.2 4.3e-18 65.1 0.1 2.4 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 KFH46470.1 - 1.3e-11 44.5 2.6 9.8e-07 28.8 0.0 5.2 4 2 0 4 4 4 2 PAS fold PAS PF00989.19 KFH46470.1 - 4.7e-08 32.7 0.2 0.04 13.7 0.0 4.2 5 0 0 5 5 5 3 PAS fold PAS_8 PF13188.1 KFH46470.1 - 8.6e-05 22.2 0.0 1.9 8.4 0.0 3.7 3 0 0 3 3 3 2 PAS domain PAS_10 PF13596.1 KFH46470.1 - 0.00017 21.7 0.0 1.8 8.9 0.0 4.1 4 0 0 4 4 4 2 PAS domain HATPase_c_3 PF13589.1 KFH46470.1 - 0.093 12.3 0.1 0.38 10.3 0.0 2.1 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1772 PF08592.6 KFH46471.1 - 4.4e-23 81.5 3.3 4.8e-23 81.4 2.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF4190 PF13828.1 KFH46471.1 - 0.016 14.7 0.5 0.66 9.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) Cornichon PF03311.9 KFH46472.1 - 2.5e-54 182.8 9.3 2.9e-54 182.6 6.4 1.0 1 0 0 1 1 1 1 Cornichon protein SNARE PF05739.14 KFH46473.1 - 7.2e-14 51.2 5.9 7.2e-14 51.2 4.1 2.5 2 1 1 3 3 3 1 SNARE domain Syntaxin PF00804.20 KFH46473.1 - 9.4e-05 22.5 3.5 9.4e-05 22.5 2.4 2.5 1 1 2 3 3 3 1 Syntaxin DUF912 PF06024.7 KFH46473.1 - 0.0016 18.4 0.0 0.0058 16.6 0.0 1.9 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Syntaxin_2 PF14523.1 KFH46473.1 - 0.044 13.8 9.5 0.057 13.4 2.7 2.3 2 0 0 2 2 2 0 Syntaxin-like protein DUF4094 PF13334.1 KFH46473.1 - 0.091 13.1 1.5 0.24 11.7 0.2 2.4 2 1 0 3 3 3 0 Domain of unknown function (DUF4094) Rifin_STEVOR PF02009.11 KFH46473.1 - 0.18 11.3 10.0 0.46 10.0 6.9 1.7 1 1 0 1 1 1 0 Rifin/stevor family Vac_Fusion PF02346.11 KFH46473.1 - 0.19 11.1 1.9 11 5.5 0.1 3.1 3 0 0 3 3 3 0 Chordopoxvirus fusion protein Herpes_U30 PF04523.8 KFH46473.1 - 0.36 8.2 3.7 0.49 7.7 2.6 1.1 1 0 0 1 1 1 0 Herpes virus tegument protein U30 DUF3753 PF12575.3 KFH46473.1 - 0.64 9.8 3.0 1.2 8.9 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) IFT57 PF10498.4 KFH46473.1 - 0.9 8.2 8.4 1 8.0 5.2 1.5 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Fungal_trans PF04082.13 KFH46474.1 - 3.4e-20 72.0 0.0 7.9e-20 70.8 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH46474.1 - 1.9e-09 37.2 9.2 3.4e-09 36.4 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FimP PF09766.4 KFH46474.1 - 1.3e-05 24.4 8.1 1.3e-05 24.4 5.6 1.9 2 0 0 2 2 2 1 Fms-interacting protein Spore_coat_CotO PF14153.1 KFH46474.1 - 0.0013 18.2 13.0 0.0026 17.2 9.0 1.4 1 0 0 1 1 1 1 Spore coat protein CotO Ycf1 PF05758.7 KFH46474.1 - 0.011 13.4 3.7 0.015 13.0 2.5 1.1 1 0 0 1 1 1 0 Ycf1 Med15 PF09606.5 KFH46474.1 - 0.19 9.9 39.5 0.29 9.3 27.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4337 PF14235.1 KFH46474.1 - 0.28 11.0 14.9 4.5 7.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) NARP1 PF12569.3 KFH46474.1 - 0.45 9.1 15.6 0.75 8.4 10.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Presenilin PF01080.12 KFH46474.1 - 0.72 8.6 8.1 1.3 7.7 5.6 1.3 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.1 KFH46474.1 - 0.79 9.4 13.2 0.069 12.8 5.7 1.7 2 0 0 2 2 2 0 Protein Family FAM60A Glyco_transf_6 PF03414.8 KFH46474.1 - 1.1 7.6 5.5 1.8 6.9 3.8 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 6 CDK5_activator PF03261.10 KFH46474.1 - 1.5 8.0 12.6 2.6 7.3 8.7 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DHHW PF14286.1 KFH46474.1 - 1.6 7.9 6.8 2.8 7.1 4.7 1.3 1 0 0 1 1 1 0 DHHW protein AAA_23 PF13476.1 KFH46474.1 - 1.7 8.8 11.3 2.9 8.1 7.8 1.3 1 0 0 1 1 1 0 AAA domain PAT1 PF09770.4 KFH46474.1 - 2 6.5 32.8 3.4 5.7 22.7 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AUX_IAA PF02309.11 KFH46474.1 - 2.9 7.5 14.2 0.36 10.5 5.7 2.3 3 0 0 3 3 3 0 AUX/IAA family eIF-3_zeta PF05091.7 KFH46474.1 - 3 6.3 22.8 4.6 5.7 15.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PIH1 PF08190.7 KFH46474.1 - 3.9 6.8 20.3 8.4 5.7 14.1 1.4 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 AvrE PF11725.3 KFH46474.1 - 9.1 3.1 16.2 13 2.6 11.2 1.1 1 0 0 1 1 1 0 Pathogenicity factor DUF95 PF01944.12 KFH46475.1 - 0.1 12.2 11.9 0.1 12.2 2.4 2.5 2 1 0 2 2 2 0 Integral membrane protein DUF95 PCI PF01399.22 KFH46476.1 - 0.051 13.9 0.0 0.26 11.6 0.0 2.2 2 0 0 2 2 2 0 PCI domain Dimer_Tnp_Tn5 PF02281.11 KFH46476.1 - 0.076 13.1 0.1 0.49 10.5 0.2 2.1 2 0 0 2 2 2 0 Transposase Tn5 dimerisation domain SET PF00856.23 KFH46477.1 - 0.0083 16.4 0.3 0.036 14.3 0.2 1.8 1 1 0 1 1 1 1 SET domain WLM PF08325.5 KFH46478.1 - 1.4e-52 178.2 0.0 2.1e-52 177.7 0.0 1.2 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 KFH46478.1 - 3.5e-06 26.0 11.5 1.4e-05 24.0 1.6 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.2 KFH46478.1 - 0.007 16.1 10.6 0.037 13.8 7.4 2.0 1 1 0 1 1 1 1 Double zinc ribbon SprT-like PF10263.4 KFH46478.1 - 0.031 13.9 1.7 0.077 12.6 0.0 2.4 3 0 0 3 3 3 0 SprT-like family DUF45 PF01863.12 KFH46478.1 - 0.054 13.2 1.0 0.12 12.1 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF45 PIG-H PF10181.4 KFH46478.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 GPI-GlcNAc transferase complex, PIG-H component CR6_interact PF10147.4 KFH46479.1 - 0.018 14.3 6.1 0.032 13.5 4.2 1.3 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF1525 PF07511.6 KFH46479.1 - 0.26 11.3 3.6 2.6 8.0 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1525) DUF4239 PF14023.1 KFH46479.1 - 0.78 9.0 4.2 1.2 8.5 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Mnd1 PF03962.10 KFH46479.1 - 1.9 8.1 6.0 3.3 7.3 4.2 1.3 1 0 0 1 1 1 0 Mnd1 family FUSC PF04632.7 KFH46479.1 - 9.4 4.5 6.0 12 4.2 4.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family RasGAP_C PF03836.10 KFH46480.1 - 2e-46 157.2 3.4 8e-46 155.2 2.4 2.2 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 KFH46480.1 - 4.2e-39 134.2 0.0 1.1e-38 132.8 0.0 1.8 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 KFH46480.1 - 2.2e-19 67.1 37.5 0.00094 18.6 0.1 12.6 13 0 0 13 13 13 7 IQ calmodulin-binding motif CH PF00307.26 KFH46480.1 - 2.6e-10 40.3 0.0 8.8e-10 38.5 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain Ribosomal_S5 PF00333.15 KFH46481.1 - 2.2e-28 97.7 2.4 2.2e-28 97.7 1.7 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 KFH46481.1 - 8.7e-21 72.9 0.1 1.7e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.1 KFH46481.1 - 0.053 13.9 10.8 0.053 13.9 7.5 1.6 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 IMS PF00817.15 KFH46482.1 - 1.2e-42 145.1 0.1 3e-42 143.9 0.1 1.7 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 KFH46482.1 - 7.1e-15 55.0 0.0 1.5e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KFH46482.1 - 0.0042 17.0 0.0 0.01 15.8 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif Abhydrolase_6 PF12697.2 KFH46483.1 - 6.7e-12 45.7 0.4 1.1e-11 45.0 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH46483.1 - 3.1e-10 39.9 0.0 4.4e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KFH46483.1 - 2.8e-06 27.0 0.1 6.9e-06 25.7 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 KFH46483.1 - 0.029 13.9 0.0 0.06 12.9 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold FKBP_C PF00254.23 KFH46485.1 - 2.3e-34 117.2 0.0 3.4e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF883 PF05957.8 KFH46485.1 - 0.082 13.3 1.3 0.15 12.4 0.9 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Med8 PF10232.4 KFH46486.1 - 3.5e-26 92.1 0.7 4.2e-26 91.8 0.5 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 CobT PF06213.7 KFH46486.1 - 0.019 14.1 7.4 0.025 13.7 5.1 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2201_N PF13203.1 KFH46486.1 - 0.053 12.6 0.9 0.08 12.0 0.6 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Rotamase PF00639.16 KFH46486.1 - 0.056 14.1 0.0 0.12 13.1 0.0 1.5 1 0 0 1 1 1 0 PPIC-type PPIASE domain T2SM_b PF10741.4 KFH46486.1 - 0.13 11.9 0.6 0.59 9.7 0.2 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b CDC45 PF02724.9 KFH46486.1 - 0.13 10.2 5.8 0.17 9.8 4.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.6 KFH46486.1 - 0.67 8.8 7.4 0.95 8.3 5.2 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nop14 PF04147.7 KFH46486.1 - 2.1 6.1 11.3 3.1 5.5 7.8 1.3 1 0 0 1 1 1 0 Nop14-like family zf-DHHC PF01529.15 KFH46487.1 - 2.1e-30 105.3 2.1 2.1e-30 105.3 1.5 1.7 1 1 0 1 1 1 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 KFH46487.1 - 0.011 15.5 0.7 0.028 14.1 0.5 1.6 1 0 0 1 1 1 0 Transglutaminase-like superfamily DZR PF12773.2 KFH46487.1 - 1.8 8.4 9.8 3.2 7.6 6.8 1.3 1 0 0 1 1 1 0 Double zinc ribbon DAHP_synth_2 PF01474.11 KFH46488.1 - 1.2e-192 640.1 0.0 1.4e-192 639.9 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Prenyltrans PF00432.16 KFH46490.1 - 1.4e-27 94.8 8.4 1.3e-08 34.2 0.1 5.6 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 KFH46490.1 - 2.1e-24 85.6 0.3 2.9e-11 43.3 0.1 5.6 4 2 1 5 5 5 4 Prenyltransferase-like Prenyltrans_2 PF13249.1 KFH46490.1 - 3.4e-23 82.2 0.3 3e-14 53.3 0.2 4.9 3 1 2 5 5 5 4 Prenyltransferase-like Pec_lyase PF09492.5 KFH46490.1 - 2.9e-05 23.4 3.5 0.2 10.7 0.0 4.8 5 1 0 6 6 6 2 Pectic acid lyase A2M_comp PF07678.9 KFH46490.1 - 0.0022 17.2 0.5 0.32 10.2 0.0 3.7 2 1 1 3 3 3 1 A-macroglobulin complement component K_channel_TID PF07941.6 KFH46492.1 - 0.23 11.7 10.2 0.5 10.6 7.1 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain SCIMP PF15050.1 KFH46492.1 - 3.6 7.5 4.6 8.5 6.2 3.2 1.6 1 0 0 1 1 1 0 SCIMP protein TauD PF02668.11 KFH46493.1 - 5.8e-47 160.5 0.0 7.4e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KFH46493.1 - 0.032 13.1 0.0 0.094 11.5 0.0 1.7 2 0 0 2 2 2 0 CsiD 2OG-FeII_Oxy_3 PF13640.1 KFH46493.1 - 0.1 13.1 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily TRI12 PF06609.8 KFH46494.1 - 7e-25 87.2 8.8 8e-25 87.0 6.1 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Mg_trans_NIPA PF05653.9 KFH46498.1 - 4e-15 55.5 11.3 5.6e-15 55.0 7.9 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 KFH46498.1 - 0.00028 20.9 19.2 0.0019 18.2 0.1 3.2 2 1 1 3 3 3 2 EamA-like transporter family TAFII28 PF04719.9 KFH46499.1 - 5.6e-20 70.9 0.8 6.7e-19 67.4 0.6 2.1 1 1 0 1 1 1 1 hTAFII28-like protein conserved region EI24 PF07264.6 KFH46500.1 - 0.00012 21.5 6.1 0.0003 20.2 4.3 1.7 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) FA_desaturase PF00487.19 KFH46500.1 - 0.8 9.0 7.3 5.2 6.4 1.7 2.1 2 0 0 2 2 2 0 Fatty acid desaturase SRF-TF PF00319.13 KFH46501.1 - 8.7e-24 82.5 0.4 1.2e-23 82.0 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CDC45 PF02724.9 KFH46501.1 - 0.083 10.9 0.3 0.097 10.6 0.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Filament PF00038.16 KFH46502.1 - 0.0059 16.1 13.8 0.01 15.3 9.6 1.5 1 1 0 1 1 1 1 Intermediate filament protein GvpK PF05121.7 KFH46502.1 - 0.014 15.1 3.7 0.014 15.1 2.6 2.4 1 1 1 2 2 2 0 Gas vesicle protein K AAA_13 PF13166.1 KFH46502.1 - 0.04 12.4 3.6 0.054 11.9 2.5 1.2 1 0 0 1 1 1 0 AAA domain Mnd1 PF03962.10 KFH46502.1 - 0.041 13.5 14.2 0.23 11.1 0.6 2.4 1 1 1 2 2 2 0 Mnd1 family Spc7 PF08317.6 KFH46502.1 - 0.059 12.0 11.2 0.13 10.9 6.6 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein BBP1_C PF15272.1 KFH46502.1 - 0.067 12.7 3.5 0.11 12.0 1.7 1.9 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal BLOC1_2 PF10046.4 KFH46502.1 - 0.078 13.1 0.5 0.078 13.1 0.4 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.10 KFH46502.1 - 0.22 11.0 20.0 0.73 9.3 1.2 4.0 2 1 1 3 3 3 0 Septum formation initiator DUF4618 PF15397.1 KFH46502.1 - 0.25 10.6 11.6 0.12 11.6 2.9 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4618) Bacillus_HBL PF05791.6 KFH46502.1 - 0.32 10.3 2.0 3.5 6.9 0.2 2.2 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Cluap1 PF10234.4 KFH46502.1 - 0.74 8.9 11.5 2.2 7.3 7.7 1.9 1 1 1 2 2 2 0 Clusterin-associated protein-1 IncA PF04156.9 KFH46502.1 - 0.79 9.2 23.7 1.7 8.2 13.4 2.6 2 1 0 2 2 2 0 IncA protein Spc24 PF08286.6 KFH46502.1 - 1.4 8.6 15.3 0.044 13.4 1.6 3.1 3 1 0 3 3 3 0 Spc24 subunit of Ndc80 DUF342 PF03961.8 KFH46502.1 - 1.4 7.2 7.7 0.33 9.2 2.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF4515 PF14988.1 KFH46502.1 - 2.1 7.9 14.6 0.26 10.9 2.4 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4515) GAS PF13851.1 KFH46502.1 - 2.3 7.3 16.5 0.57 9.3 1.8 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Laminin_II PF06009.7 KFH46502.1 - 4.3 7.0 10.5 0.84 9.3 2.5 2.7 2 1 1 3 3 3 0 Laminin Domain II TBPIP PF07106.8 KFH46502.1 - 5.1 6.6 11.7 2 7.9 1.9 2.6 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TPR_MLP1_2 PF07926.7 KFH46502.1 - 6.1 6.6 19.0 3.9 7.2 1.8 3.5 3 2 0 3 3 2 0 TPR/MLP1/MLP2-like protein MerR-DNA-bind PF09278.6 KFH46502.1 - 7.5 7.0 19.2 5.4 7.4 3.7 3.8 2 1 0 3 3 3 0 MerR, DNA binding Bap31 PF05529.7 KFH46502.1 - 8.9 5.7 9.4 3 7.2 1.3 2.4 2 1 0 2 2 2 0 B-cell receptor-associated protein 31-like Dyp_perox PF04261.7 KFH46504.1 - 7.6e-94 313.9 0.0 8.8e-94 313.7 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family DUF2382 PF09557.5 KFH46504.1 - 0.14 12.0 1.7 0.23 11.3 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2382) TRI12 PF06609.8 KFH46505.1 - 6.5e-85 285.5 19.0 8.7e-85 285.1 13.1 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KFH46505.1 - 7.5e-26 90.6 46.7 1.9e-25 89.3 30.8 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH46505.1 - 3.5e-07 29.1 32.2 5.7e-05 21.8 20.1 3.6 2 1 1 3 3 3 1 Sugar (and other) transporter FixP_N PF14715.1 KFH46505.1 - 1.2 8.5 5.9 1.6 8.1 1.4 2.9 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP DEAD PF00270.24 KFH46506.1 - 2e-42 144.5 0.0 5.8e-42 143.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFH46506.1 - 2.7e-21 75.2 0.1 2.7e-21 75.2 0.1 2.5 3 1 0 3 3 3 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KFH46506.1 - 2.3e-05 23.3 0.0 3.5e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C_2 PF13307.1 KFH46506.1 - 0.024 14.5 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain CMS1 PF14617.1 KFH46506.1 - 0.035 13.1 0.0 0.074 12.1 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 KFH46506.1 - 0.059 11.7 0.0 2.3 6.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) DUF3400 PF11880.3 KFH46506.1 - 0.12 11.6 0.5 0.3 10.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3400) SecA_DEAD PF07517.9 KFH46506.1 - 0.14 11.4 0.1 0.39 9.9 0.0 1.8 2 0 0 2 2 2 0 SecA DEAD-like domain DUF1688 PF07958.6 KFH46507.1 - 3.8e-175 582.4 0.0 4.4e-175 582.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) PQ-loop PF04193.9 KFH46509.1 - 1.2e-37 127.2 11.9 1.9e-21 75.3 0.3 2.8 3 0 0 3 3 3 2 PQ loop repeat Herpes_gE PF02480.11 KFH46509.1 - 0.021 13.1 0.4 0.15 10.3 0.0 2.0 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E ER_lumen_recept PF00810.13 KFH46509.1 - 0.26 11.7 3.3 7.3 7.0 0.4 2.7 2 1 1 3 3 3 0 ER lumen protein retaining receptor Intg_mem_TP0381 PF09529.5 KFH46509.1 - 2.7 7.1 7.9 1.1 8.4 0.7 2.6 2 1 0 2 2 2 0 Integral membrane protein (intg_mem_TP0381) 60KD_IMP PF02096.15 KFH46510.1 - 1.2e-26 93.6 0.2 2e-26 92.9 0.1 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein UQ_con PF00179.21 KFH46512.1 - 1.2e-51 173.7 0.0 1.4e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PLU-1 PF08429.6 KFH46513.1 - 4.5e-95 318.3 11.7 1.6e-89 300.1 7.6 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 KFH46513.1 - 2.4e-43 147.0 0.4 5.4e-43 145.8 0.2 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 KFH46513.1 - 3.5e-25 87.6 0.3 1.2e-24 85.9 0.1 2.1 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain PHD PF00628.24 KFH46513.1 - 4e-16 58.4 24.1 1.1e-10 40.9 4.0 3.3 3 0 0 3 3 3 2 PHD-finger JmjN PF02375.12 KFH46513.1 - 3.7e-15 55.1 1.1 9.6e-15 53.8 0.7 1.8 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 KFH46513.1 - 7.3e-14 51.5 4.8 2.2e-13 50.0 3.4 1.9 1 0 0 1 1 1 1 C5HC2 zinc finger zf-PHD-like PF15446.1 KFH46513.1 - 9.1e-05 21.8 8.5 0.00079 18.7 0.5 2.7 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.1 KFH46513.1 - 0.0027 16.9 1.4 0.0027 16.9 1.0 2.8 2 0 0 2 2 2 1 PHD-finger Mgr1 PF08602.5 KFH46513.1 - 0.027 13.5 0.4 0.052 12.5 0.3 1.4 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit zf-RING_2 PF13639.1 KFH46513.1 - 0.12 12.2 20.6 1.3 8.8 4.3 3.0 2 0 0 2 2 2 0 Ring finger domain zf-RING_2 PF13639.1 KFH46514.1 - 1.4e-13 50.4 5.4 2.2e-13 49.8 3.8 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 KFH46514.1 - 1.4e-10 40.7 0.0 3.1e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.1 KFH46514.1 - 1.8e-09 37.4 4.9 3e-09 36.7 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFH46514.1 - 4.9e-09 36.1 1.8 9.3e-09 35.2 1.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFH46514.1 - 5.7e-09 35.4 2.7 9e-09 34.8 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFH46514.1 - 1.9e-08 33.8 3.5 2.8e-08 33.2 2.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFH46514.1 - 1.9e-07 30.6 2.6 3e-07 30.0 1.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KFH46514.1 - 0.00069 19.3 0.8 0.0012 18.6 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KFH46514.1 - 0.043 13.5 2.3 0.099 12.3 1.6 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFH46514.1 - 0.047 13.5 3.3 0.17 11.8 2.4 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 KFH46514.1 - 0.062 13.2 2.7 0.21 11.5 1.9 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 KFH46514.1 - 0.075 13.0 3.3 0.14 12.1 2.3 1.5 1 0 0 1 1 1 0 RING-variant domain Baculo_RING PF05883.6 KFH46514.1 - 0.11 12.3 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_4 PF14570.1 KFH46514.1 - 0.22 11.1 2.7 0.41 10.2 1.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 KFH46514.1 - 0.46 10.0 1.9 0.82 9.2 1.3 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.6 KFH46514.1 - 0.54 10.3 3.4 1.1 9.3 2.4 1.5 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 KFH46514.1 - 0.8 9.4 2.9 1.4 8.6 2.0 1.4 1 0 0 1 1 1 0 PHD-finger DUF718 PF05336.8 KFH46515.1 - 8.8e-35 118.7 1.1 1e-34 118.4 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF718) Pkinase PF00069.20 KFH46516.1 - 4.5e-72 242.3 0.0 6.9e-72 241.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH46516.1 - 5e-37 127.3 0.1 5.6e-36 123.9 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH46516.1 - 4.1e-06 25.9 0.0 7.2e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFH46516.1 - 0.008 15.2 0.4 0.035 13.1 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFH46516.1 - 0.014 15.1 0.0 0.036 13.8 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFH46516.1 - 0.027 14.0 1.7 0.086 12.3 0.1 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase tRNA-synt_1e PF01406.14 KFH46517.1 - 7.2e-110 366.8 0.0 1e-109 366.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 KFH46517.1 - 0.0001 21.0 0.7 0.15 10.6 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.6 KFH46517.1 - 0.044 14.0 0.1 0.18 12.1 0.1 2.1 1 0 0 1 1 1 0 DALR domain DUF3449 PF11931.3 KFH46518.1 - 2.4e-73 245.8 0.2 2.4e-73 245.8 0.2 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 KFH46518.1 - 2e-12 46.4 0.1 4.4e-12 45.3 0.1 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.2 KFH46518.1 - 2e-08 34.1 2.2 1.4e-06 28.2 0.4 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFH46518.1 - 8.6e-08 32.1 2.3 1.1e-06 28.5 0.4 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFH46518.1 - 0.00045 20.2 0.2 0.017 15.1 0.1 2.7 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) DUF951 PF06107.6 KFH46518.1 - 0.026 14.0 0.0 0.096 12.2 0.0 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF951) DUF1610 PF07754.6 KFH46518.1 - 0.095 12.8 1.2 0.32 11.1 0.8 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) zf-C2H2 PF00096.21 KFH46518.1 - 0.32 11.4 3.8 3.3 8.2 0.3 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFH46518.1 - 1.1 9.6 3.8 18 5.9 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger PEP_mutase PF13714.1 KFH46519.1 - 6.2e-62 208.9 0.4 7.1e-62 208.7 0.2 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ADH_zinc_N PF00107.21 KFH46520.1 - 2.9e-07 30.1 0.0 5.6e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFH46520.1 - 2.5e-05 23.9 0.0 5.9e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.16 KFH46520.1 - 0.014 14.8 0.1 0.019 14.3 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family AlaDh_PNT_C PF01262.16 KFH46520.1 - 0.087 12.3 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Zn_clus PF00172.13 KFH46521.1 - 2.4e-09 36.9 11.5 4.6e-09 36.0 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dor1 PF04124.7 KFH46521.1 - 0.03 12.8 0.1 0.04 12.3 0.1 1.1 1 0 0 1 1 1 0 Dor1-like family p450 PF00067.17 KFH46522.1 - 2.9e-72 243.6 0.0 3.9e-72 243.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 KFH46522.1 - 4e-32 111.4 0.0 6.4e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KFH46522.1 - 1.5e-24 86.6 0.0 3.8e-24 85.3 0.0 1.8 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KFH46522.1 - 2.6e-13 50.5 0.0 5.8e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KFH46522.1 - 0.0057 16.6 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain Sugar_tr PF00083.19 KFH46524.1 - 9.5e-29 100.2 30.8 1.2e-27 96.6 21.3 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH46524.1 - 7.6e-28 97.2 31.1 7.6e-28 97.2 21.6 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily zf-C2H2 PF00096.21 KFH46525.1 - 1.9e-11 43.5 11.0 2.2e-05 24.5 1.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFH46525.1 - 1.2e-09 37.8 8.1 1.5e-05 25.0 0.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFH46525.1 - 1.4e-09 37.7 11.0 1.1e-06 28.6 1.2 3.2 4 0 0 4 4 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFH46525.1 - 0.0002 21.4 1.9 0.025 14.7 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 KFH46525.1 - 0.0039 16.9 3.5 0.024 14.4 0.3 2.5 2 0 0 2 2 2 1 BED zinc finger BolA PF01722.13 KFH46525.1 - 0.0043 16.9 0.7 0.8 9.7 0.0 2.4 1 1 1 2 2 2 1 BolA-like protein zf-CHY PF05495.7 KFH46525.1 - 0.036 14.2 3.0 0.06 13.5 2.1 1.5 1 0 0 1 1 1 0 CHY zinc finger zf-H2C2_5 PF13909.1 KFH46525.1 - 0.037 14.2 1.0 0.037 14.2 0.7 2.9 3 0 0 3 3 2 0 C2H2-type zinc-finger domain FYDLN_acid PF09538.5 KFH46525.1 - 0.095 13.2 2.7 0.22 12.0 1.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) MAGE_N PF12440.3 KFH46525.1 - 0.1 12.8 0.7 0.1 12.8 0.5 1.8 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal zf-C2HC_2 PF13913.1 KFH46525.1 - 0.97 9.1 6.2 0.16 11.6 1.4 1.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-AN1 PF01428.11 KFH46525.1 - 1.8 8.4 8.3 3.8 7.4 0.5 2.5 1 1 1 2 2 2 0 AN1-like Zinc finger C1_4 PF07975.7 KFH46525.1 - 2.4 8.2 5.5 3.1 7.8 0.1 2.5 1 1 0 2 2 2 0 TFIIH C1-like domain Hepcidin PF06446.7 KFH46525.1 - 2.8 8.4 9.3 0.15 12.4 1.3 2.3 2 0 0 2 2 2 0 Hepcidin zf-C2H2_6 PF13912.1 KFH46525.1 - 3.4 7.6 9.1 1.6 8.7 0.2 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KFH46525.1 - 8.7 6.5 8.2 0.87 9.7 0.5 2.5 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) TOM13 PF08219.6 KFH46526.1 - 2.5e-31 107.2 0.0 3.2e-31 106.9 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 Methyltransf_23 PF13489.1 KFH46527.1 - 5.8e-15 55.3 0.0 1e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH46527.1 - 3.3e-14 52.7 0.0 5.3e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH46527.1 - 5.6e-12 45.9 0.0 1.1e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH46527.1 - 1.4e-11 44.6 0.1 3.9e-11 43.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH46527.1 - 5.1e-10 39.9 0.0 1.1e-09 38.8 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFH46527.1 - 1.4e-06 28.5 0.0 2.4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFH46527.1 - 2.8e-06 26.6 0.0 3.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KFH46527.1 - 6.9e-06 26.0 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFH46527.1 - 0.00012 21.4 2.7 0.00064 19.1 0.1 2.5 2 1 0 2 2 2 1 Methyltransferase small domain Methyltransf_32 PF13679.1 KFH46527.1 - 0.016 14.8 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 KFH46527.1 - 0.06 12.2 0.0 0.11 11.2 0.0 1.7 1 1 0 1 1 1 0 DREV methyltransferase Trypsin PF00089.21 KFH46528.1 - 0.033 13.7 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Trypsin FYVE_2 PF02318.11 KFH46529.1 - 0.21 11.4 1.8 0.3 10.9 0.3 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger Nup54 PF13874.1 KFH46529.1 - 0.24 11.0 5.2 1.3 8.7 2.2 2.0 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DUF3399 PF11879.3 KFH46529.1 - 0.89 9.8 6.7 0.36 11.0 2.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3399) Uds1 PF15456.1 KFH46529.1 - 1 9.3 7.6 3.9 7.4 5.3 1.8 1 1 0 1 1 1 0 Up-regulated During Septation PAF-AH_p_II PF03403.8 KFH46530.1 - 7.8e-40 136.3 0.0 1.4e-38 132.1 0.0 2.1 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 KFH46530.1 - 5.1e-12 45.7 0.0 9.3e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFH46530.1 - 1.2e-06 28.6 0.7 3.6e-06 27.0 0.5 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KFH46530.1 - 0.0021 16.9 0.1 0.0042 16.0 0.0 1.5 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 KFH46530.1 - 0.005 15.6 0.1 0.0082 14.9 0.1 1.2 1 0 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.3 KFH46530.1 - 0.056 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase DLH PF01738.13 KFH46530.1 - 0.12 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Ank_2 PF12796.2 KFH46532.1 - 3.5e-29 100.9 1.3 2.4e-14 53.4 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFH46532.1 - 2.1e-14 52.4 0.8 1.6e-08 33.9 0.2 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KFH46532.1 - 3.4e-14 52.5 0.4 1.2e-08 34.8 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFH46532.1 - 2.7e-11 43.6 0.9 9.2e-06 26.0 0.0 2.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFH46532.1 - 3.3e-10 39.1 0.1 0.0018 18.3 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat DUF2630 PF10944.3 KFH46533.1 - 0.026 14.6 0.5 0.039 14.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) Pox_A_type_inc PF04508.7 KFH46533.1 - 0.12 12.2 0.8 0.3 10.9 0.5 1.8 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat SEP PF08059.8 KFH46534.1 - 3.2e-25 88.2 0.0 5.4e-25 87.4 0.0 1.4 1 0 0 1 1 1 1 SEP domain UBA_4 PF14555.1 KFH46534.1 - 3.2e-13 48.9 0.0 5.8e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 KFH46534.1 - 5.6e-12 45.5 0.0 9.8e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 UBX domain SGS PF05002.10 KFH46535.1 - 1.2e-26 92.2 2.7 1.2e-26 92.2 1.8 2.5 2 0 0 2 2 2 1 SGS domain CS PF04969.11 KFH46535.1 - 2.2e-07 31.3 0.3 4e-07 30.4 0.2 1.4 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 KFH46535.1 - 3.2e-05 23.4 2.9 8e-05 22.2 0.5 2.3 2 0 0 2 2 2 1 TPR repeat DUF3856 PF12968.2 KFH46535.1 - 0.014 15.2 2.1 0.036 13.9 0.4 2.4 2 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_2 PF07719.12 KFH46535.1 - 0.065 13.1 4.0 4.3 7.4 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2360 PF10152.4 KFH46535.1 - 2.3 8.5 11.2 3 8.1 1.2 2.5 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) TPR_16 PF13432.1 KFH46535.1 - 2.9 8.6 13.9 0.048 14.3 1.8 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFH46535.1 - 9.1 7.2 7.7 54 4.8 0.1 3.9 2 2 1 3 3 3 0 Tetratricopeptide repeat YcaO PF02624.11 KFH46536.1 - 0.025 14.0 0.7 0.03 13.8 0.5 1.2 1 0 0 1 1 1 0 YcaO-like family SpoVR PF04293.8 KFH46536.1 - 0.045 12.1 0.6 0.056 11.8 0.4 1.1 1 0 0 1 1 1 0 SpoVR like protein eRF1_3 PF03465.10 KFH46536.1 - 0.097 12.9 0.0 0.15 12.3 0.0 1.4 1 1 0 1 1 1 0 eRF1 domain 3 DUF1996 PF09362.5 KFH46537.1 - 1.7e-72 243.8 0.4 4.4e-72 242.5 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) Glyco_transf_21 PF13506.1 KFH46538.1 - 3e-15 55.9 0.1 3.4e-07 29.7 0.0 3.3 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 KFH46538.1 - 9.1e-15 55.0 0.0 1.4e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KFH46538.1 - 2.5e-07 30.5 0.0 6.1e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 CBM_5_12_2 PF14600.1 KFH46539.1 - 0.041 13.5 0.0 0.09 12.4 0.0 1.5 1 0 0 1 1 1 0 Cellulose-binding domain tRNA_int_endo PF01974.12 KFH46540.1 - 4.3e-19 68.1 0.1 8e-19 67.2 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 KFH46540.1 - 3.2e-05 23.4 0.0 0.11 12.1 0.0 2.3 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Amidohydro_2 PF04909.9 KFH46541.1 - 2.2e-10 40.5 0.6 7.8e-10 38.7 0.4 1.9 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KFH46541.1 - 1.8e-05 24.5 0.2 0.001 18.7 0.2 3.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KFH46541.1 - 5e-05 23.4 1.7 0.00011 22.4 1.2 1.5 1 1 0 1 1 1 1 Amidohydrolase CoA_binding_2 PF13380.1 KFH46541.1 - 0.0067 16.5 0.1 0.021 14.9 0.0 1.9 1 0 0 1 1 1 1 CoA binding domain S1-P1_nuclease PF02265.11 KFH46542.1 - 3.6e-70 236.4 0.2 4.1e-70 236.2 0.2 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease CENP-B_dimeris PF09026.5 KFH46543.1 - 1.1 9.5 0.1 1.1 9.5 0.0 3.0 3 0 0 3 3 3 0 Centromere protein B dimerisation domain vATP-synt_E PF01991.13 KFH46544.1 - 4.5e-63 212.1 12.1 5.3e-63 211.8 8.4 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit AAA_15 PF13175.1 KFH46544.1 - 0.011 14.7 8.0 0.014 14.4 5.5 1.1 1 0 0 1 1 1 0 AAA ATPase domain Methyltransf_7 PF03492.10 KFH46544.1 - 0.069 11.8 2.7 0.66 8.6 2.5 1.8 2 0 0 2 2 2 0 SAM dependent carboxyl methyltransferase DnaI_N PF07319.6 KFH46544.1 - 0.071 13.3 5.6 1.1 9.5 0.7 2.6 1 1 0 2 2 2 0 Primosomal protein DnaI N-terminus Gluconate_2-dh3 PF13618.1 KFH46544.1 - 1.2 9.2 7.2 2 8.5 2.9 2.6 2 1 1 3 3 3 0 Gluconate 2-dehydrogenase subunit 3 Aldedh PF00171.17 KFH46545.1 - 3.6e-119 398.1 0.1 4.4e-119 397.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LANC_like PF05147.8 KFH46546.1 - 2.9e-31 108.3 0.0 4e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein TPP_enzyme_N PF02776.13 KFH46548.1 - 6.5e-41 139.6 0.4 1.7e-40 138.2 0.2 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KFH46548.1 - 1.8e-21 76.2 0.1 4.6e-21 74.9 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KFH46548.1 - 1.6e-19 69.9 0.0 5.5e-19 68.2 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain GTP_cyclohydroI PF01227.17 KFH46549.1 - 6.2e-74 247.1 0.1 8.8e-74 246.6 0.1 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 KFH46549.1 - 0.00048 20.0 0.0 0.00093 19.0 0.0 1.5 1 0 0 1 1 1 1 QueF-like protein Pec_lyase_C PF00544.14 KFH46551.1 - 1.2e-39 135.9 2.4 1.8e-39 135.3 1.7 1.3 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 KFH46551.1 - 1.1e-05 25.1 4.4 0.00024 20.8 3.0 2.2 1 1 0 1 1 1 1 Right handed beta helix region Tetraspannin PF00335.15 KFH46552.1 - 1.2e-06 27.9 4.2 1.7e-06 27.4 2.9 1.3 1 0 0 1 1 1 1 Tetraspanin family DUF4282 PF14110.1 KFH46552.1 - 2.5 8.3 6.6 0.5 10.5 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) Ipi1_N PF12333.3 KFH46553.1 - 1.8e-21 76.0 0.0 7e-21 74.1 0.0 1.9 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation UPF0113 PF03657.8 KFH46554.1 - 7.5e-07 28.9 0.0 9.7e-07 28.5 0.0 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0113) Nol1_Nop2_Fmu_2 PF13636.1 KFH46554.1 - 0.021 14.8 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 pre-rRNA processing and ribosome biogenesis E1-E2_ATPase PF00122.15 KFH46556.1 - 4.8e-13 48.6 0.0 1.4e-12 47.1 0.0 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KFH46556.1 - 4.6e-12 45.7 0.1 1.6e-11 43.9 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 KFH46556.1 - 1.6e-10 41.7 0.3 7.8e-08 32.9 0.2 3.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFH46556.1 - 5e-10 39.8 0.0 1.7e-09 38.1 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFH46556.1 - 0.009 15.6 0.4 0.027 14.0 0.3 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4484 PF14831.1 KFH46556.1 - 0.016 15.3 0.4 0.049 13.7 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) tRNA-synt_2b PF00587.20 KFH46557.1 - 2.2e-62 209.6 0.0 3.2e-62 209.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KFH46557.1 - 2.9e-20 71.9 0.0 6.5e-20 70.8 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Zn_clus PF00172.13 KFH46558.1 - 8.3e-08 32.0 12.1 1.4e-07 31.3 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phostensin_N PF13916.1 KFH46558.1 - 4.3 7.4 7.0 12 6.0 4.9 1.7 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal Macoilin PF09726.4 KFH46558.1 - 5.1 5.2 17.5 1.2 7.2 2.5 2.1 2 0 0 2 2 2 0 Transmembrane protein Abhydrolase_6 PF12697.2 KFH46560.1 - 6.1e-15 55.7 7.9 1.2e-14 54.7 5.5 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH46560.1 - 3.8e-12 46.1 0.3 7.1e-12 45.3 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 KFH46560.1 - 1.4e-10 40.8 0.9 2e-05 23.9 0.0 2.2 2 0 0 2 2 2 2 Secretory lipase Abhydrolase_1 PF00561.15 KFH46560.1 - 0.0042 16.6 0.1 0.16 11.5 0.1 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KFH46560.1 - 0.095 12.2 0.3 0.2 11.2 0.2 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.13 KFH46560.1 - 0.096 11.9 0.0 2.3 7.4 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family MFS_1 PF07690.11 KFH46561.1 - 4.1e-29 101.4 30.1 4.1e-29 101.4 20.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TMEM237 PF15383.1 KFH46561.1 - 1.7 7.7 4.6 0.58 9.2 0.1 2.0 2 0 0 2 2 2 0 Transmembrane protein 237 DUF4105 PF13387.1 KFH46562.1 - 0.12 11.5 0.0 0.13 11.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) Amnionless PF14828.1 KFH46563.1 - 0.0017 16.9 0.0 0.0023 16.5 0.0 1.2 1 0 0 1 1 1 1 Amnionless Lsm_interact PF05391.6 KFH46563.1 - 0.1 12.0 0.4 0.26 10.7 0.3 1.7 1 0 0 1 1 1 0 Lsm interaction motif DUF1010 PF06231.6 KFH46563.1 - 0.13 12.2 0.8 0.24 11.4 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1010) TPR_11 PF13414.1 KFH46564.1 - 7.3e-10 38.3 0.1 1.2e-08 34.4 0.0 2.6 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 KFH46564.1 - 2.7e-06 26.8 0.0 0.89 9.6 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFH46564.1 - 9.9e-06 24.9 0.2 0.065 12.8 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFH46564.1 - 0.00044 20.1 4.2 0.00073 19.4 0.0 2.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFH46564.1 - 0.0044 17.6 1.6 0.017 15.8 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat UBA PF00627.26 KFH46564.1 - 0.0051 16.6 0.0 0.013 15.3 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain DnaJ PF00226.26 KFH46564.1 - 0.0087 15.7 0.0 0.028 14.1 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain Semialdhyde_dhC PF02774.13 KFH46565.1 - 9.6e-39 133.1 0.0 1.3e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 KFH46565.1 - 2.1e-28 99.0 0.0 7e-28 97.3 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KFH46565.1 - 0.037 13.9 0.0 0.069 13.0 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ank_2 PF12796.2 KFH46566.1 - 3.3e-12 46.5 0.0 4.7e-07 30.0 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFH46566.1 - 6.5e-10 38.3 0.4 0.031 14.0 0.1 5.3 4 2 1 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 KFH46566.1 - 1.6e-09 37.1 0.0 0.055 13.7 0.0 5.9 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.1 KFH46566.1 - 1.2e-08 35.2 0.0 0.011 16.1 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFH46566.1 - 6.2e-07 29.4 0.9 0.028 14.6 0.0 3.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) MFS_1 PF07690.11 KFH46567.1 - 2.1e-20 72.7 27.4 3.7e-20 71.9 19.0 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily GIY-YIG PF01541.19 KFH46568.1 - 3.7e-09 36.8 0.0 8e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-HC5HC2H_2 PF13832.1 KFH46568.1 - 0.025 14.5 0.1 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain T5orf172 PF10544.4 KFH46568.1 - 0.068 13.5 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 T5orf172 domain DiS_P_DiS PF06750.8 KFH46568.1 - 0.1 12.3 0.0 7 6.5 0.0 2.7 3 0 0 3 3 3 0 Bacterial Peptidase A24 N-terminal domain zf-HC5HC2H PF13771.1 KFH46568.1 - 0.14 12.3 1.1 0.22 11.6 0.7 1.3 1 0 0 1 1 1 0 PHD-like zinc-binding domain Prok-RING_1 PF14446.1 KFH46568.1 - 0.21 11.3 4.7 0.55 10.0 0.5 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Transferase PF02458.10 KFH46569.1 - 7.1e-09 34.5 0.0 7.9e-08 31.1 0.0 2.2 2 1 0 2 2 2 1 Transferase family GCD14 PF08704.5 KFH46571.1 - 1.1e-62 211.7 0.0 3.4e-44 151.1 0.0 2.6 2 1 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 KFH46571.1 - 0.00013 22.0 0.0 0.00031 20.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH46571.1 - 0.014 15.9 0.0 0.052 14.1 0.0 1.9 1 1 0 2 2 2 0 Methyltransferase domain DEAD PF00270.24 KFH46572.1 - 1.8e-40 138.2 0.4 4.6e-40 136.8 0.2 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFH46572.1 - 4.4e-29 100.1 0.2 9.1e-29 99.1 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.1 KFH46572.1 - 0.019 14.5 0.8 0.042 13.4 0.6 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KFH46572.1 - 0.019 14.6 0.2 0.049 13.3 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain ResIII PF04851.10 KFH46572.1 - 0.027 14.2 0.1 0.075 12.8 0.1 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 KFH46572.1 - 0.047 13.4 0.3 0.15 11.7 0.0 2.0 2 1 0 2 2 2 0 Flavivirus DEAD domain AAA_22 PF13401.1 KFH46572.1 - 0.083 13.0 0.7 0.41 10.7 0.5 2.0 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.9 KFH46572.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Helicase Trypsin PF00089.21 KFH46573.1 - 4.3e-16 59.1 0.1 4.7e-16 59.0 0.1 1.0 1 0 0 1 1 1 1 Trypsin LSM PF01423.17 KFH46575.1 - 8.4e-06 25.2 0.0 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 LSM domain Malate_synthase PF01274.17 KFH46576.1 - 2.9e-233 774.6 0.0 3.3e-233 774.4 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Glyco_hydro_17 PF00332.13 KFH46577.1 - 3.7e-23 82.0 0.2 1.9e-21 76.4 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Fungal_trans PF04082.13 KFH46578.1 - 2.9e-14 52.5 0.1 4.8e-14 51.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH46578.1 - 8.6e-09 35.1 12.7 1.4e-08 34.4 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Voldacs PF03517.8 KFH46579.1 - 3e-24 85.3 0.2 5.3e-24 84.5 0.2 1.4 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Gtr1_RagA PF04670.7 KFH46580.1 - 7.6e-87 290.2 0.0 1.1e-86 289.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 KFH46580.1 - 1.6e-06 27.6 0.0 3.3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFH46580.1 - 1.4e-05 25.5 0.0 2.6e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFH46580.1 - 6.4e-05 22.2 0.1 0.00017 20.9 0.1 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFH46580.1 - 8.1e-05 22.5 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 KFH46580.1 - 0.00088 18.7 0.8 0.0061 16.0 0.1 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 KFH46580.1 - 0.0022 17.4 0.0 0.0036 16.7 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 KFH46580.1 - 0.0047 17.2 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_10 PF12846.2 KFH46580.1 - 0.0058 16.1 0.0 0.0075 15.7 0.0 1.3 1 1 0 1 1 1 1 AAA-like domain DUF258 PF03193.11 KFH46580.1 - 0.028 13.5 0.0 0.049 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 G-alpha PF00503.15 KFH46580.1 - 0.029 13.0 0.4 0.61 8.7 0.1 2.2 2 0 0 2 2 2 0 G-protein alpha subunit DUF815 PF05673.8 KFH46580.1 - 0.086 11.7 0.0 0.19 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 KFH46580.1 - 0.097 11.7 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Robl_LC7 PF03259.12 KFH46581.1 - 2.3e-09 36.6 0.0 2.3e-06 27.0 0.0 2.1 2 0 0 2 2 2 2 Roadblock/LC7 domain Gly_transf_sug PF04488.10 KFH46583.1 - 6.3e-06 26.5 0.8 1.8e-05 25.0 0.5 1.7 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TRI5 PF06330.6 KFH46583.1 - 0.048 12.3 0.1 0.072 11.7 0.0 1.2 1 0 0 1 1 1 0 Trichodiene synthase (TRI5) Herpes_LMP2 PF07415.6 KFH46584.1 - 1.4 7.4 7.4 1.8 7.0 5.1 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein DUF605 PF04652.11 KFH46584.1 - 7 5.9 11.7 8.9 5.5 8.1 1.1 1 0 0 1 1 1 0 Vta1 like DUF4244 PF14029.1 KFH46585.1 - 0.084 11.9 0.6 0.13 11.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4244) UPF0139 PF03669.8 KFH46586.1 - 1.3e-05 24.6 0.6 1.8e-05 24.1 0.4 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0139) Peptidase_M14 PF00246.19 KFH46587.1 - 2.8e-20 73.0 0.0 4.4e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.9 KFH46587.1 - 0.0042 15.9 0.2 0.027 13.3 0.0 2.1 2 0 0 2 2 2 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.3 KFH46587.1 - 0.0097 15.0 0.1 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) Aa_trans PF01490.13 KFH46589.1 - 8.9e-32 110.0 32.6 1e-31 109.8 22.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KFH46589.1 - 1e-06 27.8 12.4 1e-06 27.8 8.6 2.2 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Sugar_tr PF00083.19 KFH46590.1 - 1e-74 251.8 21.9 1.2e-74 251.5 15.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH46590.1 - 1.8e-26 92.7 25.3 2.3e-23 82.4 13.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFH46590.1 - 2.2e-05 23.0 2.6 2.2e-05 23.0 1.8 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein dCMP_cyt_deam_1 PF00383.17 KFH46590.1 - 0.016 14.8 0.1 1.1 8.9 0.0 2.5 2 0 0 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region DUF2085 PF09858.4 KFH46590.1 - 5.5 7.1 11.4 0.19 11.8 0.9 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2085) RecR PF02132.10 KFH46592.1 - 0.091 12.2 0.1 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 RecR protein TPR_2 PF07719.12 KFH46593.1 - 2.6e-31 105.0 16.5 0.00037 20.2 0.1 10.5 11 0 0 11 11 10 8 Tetratricopeptide repeat Apc3 PF12895.2 KFH46593.1 - 7.9e-29 99.6 15.6 2.2e-21 75.7 0.1 5.7 4 2 4 8 8 8 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 KFH46593.1 - 1.3e-28 98.4 14.8 2.2e-10 40.0 0.0 7.6 6 1 2 8 8 8 7 TPR repeat TPR_1 PF00515.23 KFH46593.1 - 4.2e-27 92.5 8.2 9.9e-05 21.7 0.3 10.1 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.1 KFH46593.1 - 6.5e-21 74.0 14.4 0.00035 20.4 0.3 8.8 5 1 1 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 KFH46593.1 - 6.9e-20 71.1 8.3 0.025 14.8 0.0 7.7 5 3 1 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 KFH46593.1 - 7.1e-15 53.6 0.0 0.016 14.9 0.1 8.7 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFH46593.1 - 2.1e-14 52.7 19.5 0.012 16.2 0.3 10.5 5 3 7 12 12 11 4 Tetratricopeptide repeat TPR_7 PF13176.1 KFH46593.1 - 2.7e-10 39.2 12.3 1.6 8.7 0.1 9.1 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFH46593.1 - 3.4e-10 40.3 30.9 0.00025 21.6 2.0 8.2 7 2 2 9 9 8 3 Tetratricopeptide repeat TPR_10 PF13374.1 KFH46593.1 - 8.5e-10 38.2 7.3 0.027 14.4 0.4 7.5 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFH46593.1 - 1.3e-06 28.5 6.0 1.5 9.4 0.1 8.1 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFH46593.1 - 5.5e-06 26.1 15.2 0.0094 15.7 0.9 5.6 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFH46593.1 - 0.00032 20.6 0.8 34 4.9 0.0 6.4 8 0 0 8 8 6 0 Tetratricopeptide repeat Coatomer_E PF04733.9 KFH46593.1 - 0.0019 17.4 3.7 5.2 6.1 0.0 4.2 5 0 0 5 5 5 1 Coatomer epsilon subunit TPR_21 PF09976.4 KFH46593.1 - 0.083 12.8 7.3 3.1 7.7 0.5 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.4 KFH46593.1 - 0.2 11.0 2.3 10 5.4 0.0 4.1 3 1 0 4 4 4 0 26S proteasome subunit RPN7 Mito_fiss_reg PF05308.6 KFH46594.1 - 3.4 6.9 13.6 0.58 9.4 1.8 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator Fungal_trans_2 PF11951.3 KFH46595.1 - 2e-21 76.0 2.1 2.5e-18 65.8 0.1 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH46595.1 - 2.8e-08 33.5 8.7 7.1e-08 32.2 6.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MIT PF04212.13 KFH46595.1 - 0.092 12.6 0.3 0.22 11.4 0.2 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain SKIP_SNW PF02731.10 KFH46597.1 - 3.2e-63 211.9 9.7 3.2e-63 211.9 6.7 2.4 2 0 0 2 2 2 1 SKIP/SNW domain DUF3827 PF12877.2 KFH46597.1 - 3 5.8 12.9 5 5.0 8.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) FAD_binding_4 PF01565.18 KFH46599.1 - 9.1e-24 83.5 0.5 1.5e-23 82.7 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 KFH46599.1 - 0.021 14.1 0.0 0.046 13.0 0.0 1.5 1 1 0 1 1 1 0 FAD linked oxidases, C-terminal domain BBE PF08031.7 KFH46599.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Berberine and berberine like Pet127 PF08634.5 KFH46601.1 - 5.3e-118 393.1 0.3 7.6e-118 392.6 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 DUF972 PF06156.8 KFH46601.1 - 2.2 8.6 6.0 19 5.6 0.5 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Ank PF00023.25 KFH46602.1 - 2.1e-16 58.8 2.0 3.7e-07 29.6 0.2 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 KFH46602.1 - 1.5e-13 50.9 1.1 3.3e-05 24.1 0.5 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFH46602.1 - 3.4e-13 49.7 1.6 0.00029 21.2 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFH46602.1 - 3.8e-13 49.1 2.3 4.8e-07 29.8 0.3 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFH46602.1 - 5.9e-08 32.2 1.9 0.089 13.0 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 KFH46602.1 - 7e-07 28.8 0.1 6.7e-06 25.7 0.0 2.4 1 1 0 1 1 1 1 KilA-N domain AAA_13 PF13166.1 KFH46602.1 - 0.0038 15.7 4.8 0.0038 15.7 3.3 1.6 2 0 0 2 2 2 1 AAA domain HlyD PF00529.15 KFH46602.1 - 0.035 13.4 10.4 0.072 12.3 7.2 1.5 1 0 0 1 1 1 0 HlyD family secretion protein chaperone_DMP PF10448.4 KFH46602.1 - 0.12 12.2 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 20S proteasome chaperone HET PF06985.6 KFH46603.1 - 3.5e-29 101.7 0.1 5.9e-29 101.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sec2p PF06428.6 KFH46605.1 - 3.7e-10 39.5 9.4 3.7e-10 39.5 6.5 2.6 3 0 0 3 3 3 1 GDP/GTP exchange factor Sec2p Jnk-SapK_ap_N PF09744.4 KFH46605.1 - 0.00037 20.5 15.4 0.14 12.0 8.2 2.1 2 0 0 2 2 2 2 JNK_SAPK-associated protein-1 IncA PF04156.9 KFH46605.1 - 0.0011 18.5 18.6 0.022 14.3 8.9 2.1 2 0 0 2 2 2 2 IncA protein DUF737 PF05300.6 KFH46605.1 - 0.0012 18.8 12.4 0.0014 18.5 7.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF737) NeA_P2 PF12312.3 KFH46605.1 - 0.0072 15.5 0.2 0.017 14.3 0.1 1.6 1 0 0 1 1 1 1 Nepovirus subgroup A polyprotein Fib_alpha PF08702.5 KFH46605.1 - 0.012 15.7 8.2 0.46 10.5 0.0 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Gly_acyl_tr_N PF06021.6 KFH46605.1 - 0.017 14.5 0.2 0.22 10.9 0.2 2.0 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase CAF-1_p150 PF11600.3 KFH46605.1 - 0.028 13.7 15.0 0.041 13.2 10.4 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Dscam_C PF12355.3 KFH46605.1 - 0.04 14.1 0.7 0.04 14.1 0.5 1.7 2 0 0 2 2 1 0 Down syndrome cell adhesion molecule C terminal DUF2360 PF10152.4 KFH46605.1 - 0.067 13.4 13.5 0.1 12.8 8.4 2.1 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF2422 PF10337.4 KFH46605.1 - 0.08 11.7 0.7 0.089 11.5 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) DUF2387 PF09526.5 KFH46605.1 - 0.19 11.6 0.9 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) Myosin_tail_1 PF01576.14 KFH46605.1 - 0.35 8.5 26.5 0.033 11.9 13.4 2.0 2 0 0 2 2 2 0 Myosin tail FUSC PF04632.7 KFH46605.1 - 0.46 8.8 11.7 2.1 6.6 0.1 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family HAUS6_N PF14661.1 KFH46605.1 - 9 5.5 15.0 13 5.0 8.2 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus HA2 PF04408.18 KFH46606.1 - 1.2e-18 67.0 1.5 1.7e-18 66.4 0.1 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KFH46606.1 - 4.2e-13 48.9 0.0 1.7e-12 47.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFH46606.1 - 5.2e-09 35.8 0.2 1.7e-08 34.1 0.1 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 KFH46606.1 - 1.9e-08 34.0 0.0 4.7e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 KFH46606.1 - 2.8e-05 24.2 1.2 6.7e-05 23.0 0.0 2.3 3 0 0 3 3 3 1 AAA domain ResIII PF04851.10 KFH46606.1 - 0.0022 17.8 2.6 0.38 10.5 0.0 3.1 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit T2SE PF00437.15 KFH46606.1 - 0.0038 16.1 0.0 0.0075 15.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.11 KFH46606.1 - 0.019 14.2 0.0 0.051 12.7 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein KaiC PF06745.8 KFH46606.1 - 0.032 13.3 0.0 0.071 12.2 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.1 KFH46606.1 - 0.082 12.8 0.2 0.63 9.9 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KFH46606.1 - 0.098 12.9 0.0 0.098 12.9 0.0 2.8 3 0 0 3 3 2 0 AAA domain PGP_phosphatase PF09419.5 KFH46607.1 - 3.7e-65 218.3 0.0 4.3e-65 218.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 KFH46607.1 - 0.001 18.6 0.0 0.0019 17.8 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KFH46607.1 - 0.015 15.6 0.0 0.02 15.3 0.0 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase OAD_beta PF03977.8 KFH46608.1 - 0.11 11.2 0.0 0.11 11.1 0.0 1.0 1 0 0 1 1 1 0 Na+-transporting oxaloacetate decarboxylase beta subunit PhoD PF09423.5 KFH46610.1 - 6.9e-61 206.1 0.0 9.9e-61 205.6 0.0 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase DUF2393 PF09624.5 KFH46610.1 - 1.4 8.4 4.3 0.37 10.2 0.3 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2393) ArgJ PF01960.13 KFH46611.1 - 2.7e-144 480.3 0.0 3e-144 480.1 0.0 1.0 1 0 0 1 1 1 1 ArgJ family Med6 PF04934.9 KFH46612.1 - 4e-41 139.8 0.0 5.3e-41 139.4 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component ACT_7 PF13840.1 KFH46613.1 - 3.1e-25 87.4 0.0 1.3e-18 66.2 0.0 2.4 2 0 0 2 2 2 2 ACT domain DUF4032 PF13224.1 KFH46613.1 - 0.17 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4032) ketoacyl-synt PF00109.21 KFH46614.1 - 2.9e-74 249.7 0.0 5.5e-74 248.8 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Carn_acyltransf PF00755.15 KFH46614.1 - 4e-71 239.8 0.0 6e-71 239.2 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Acyl_transf_1 PF00698.16 KFH46614.1 - 1.8e-62 211.5 0.1 3.4e-62 210.6 0.1 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KFH46614.1 - 3.3e-50 170.2 0.0 1.1e-49 168.5 0.0 2.0 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KFH46614.1 - 5.1e-41 140.3 0.3 6e-40 136.8 0.0 2.7 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KFH46614.1 - 4.5e-40 136.2 0.1 1.2e-39 134.8 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 KFH46614.1 - 7.2e-38 130.4 0.2 2.5e-37 128.6 0.2 2.0 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.7 KFH46614.1 - 8.7e-18 64.6 0.0 3.8e-17 62.5 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KFH46614.1 - 1.7e-14 53.4 0.2 2.6e-13 49.6 0.0 2.8 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 KFH46614.1 - 4.9e-12 45.6 0.0 1.2e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH46614.1 - 1.1e-10 41.4 0.0 3.9e-10 39.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH46614.1 - 6.4e-10 39.3 0.0 1.8e-09 37.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFH46614.1 - 1.9e-08 33.7 0.0 5.5e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ADH_zinc_N_2 PF13602.1 KFH46614.1 - 3.3e-08 34.4 1.4 4.2e-06 27.6 0.0 4.7 7 0 0 7 7 3 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 KFH46614.1 - 4.4e-07 30.4 0.1 3.7e-06 27.4 0.0 2.7 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFH46614.1 - 7.3e-07 29.4 0.0 2.7e-06 27.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KFH46614.1 - 0.0002 21.5 0.0 0.00051 20.2 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 KFH46614.1 - 0.00035 20.3 0.6 0.0016 18.1 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 KFH46614.1 - 0.013 14.4 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain 3Beta_HSD PF01073.14 KFH46614.1 - 0.061 12.0 0.1 0.11 11.1 0.1 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DREV PF05219.7 KFH46614.1 - 0.068 12.0 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_28 PF02636.12 KFH46614.1 - 0.089 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_16 PF10294.4 KFH46614.1 - 0.09 12.2 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Metallophos PF00149.23 KFH46615.1 - 4e-42 143.8 0.6 6.3e-42 143.2 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ABC_membrane PF00664.18 KFH46616.1 - 4.4e-47 160.8 27.9 2e-26 93.0 10.7 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 KFH46616.1 - 5.5e-47 159.5 0.0 6.4e-27 94.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KFH46616.1 - 8.2e-06 25.9 0.4 3.5 7.5 0.1 4.3 4 0 0 4 4 4 1 AAA domain MMR_HSR1 PF01926.18 KFH46616.1 - 1.8e-05 24.6 0.3 0.084 12.8 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 KFH46616.1 - 4.3e-05 24.0 0.6 0.2 12.1 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein SMC_N PF02463.14 KFH46616.1 - 0.00014 21.1 1.5 3 7.0 0.0 3.4 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KFH46616.1 - 0.00018 20.9 1.8 0.22 11.1 0.0 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KFH46616.1 - 0.00032 20.7 0.1 0.16 11.9 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.12 KFH46616.1 - 0.00072 19.4 2.1 0.13 12.0 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 DUF258 PF03193.11 KFH46616.1 - 0.00094 18.3 2.0 0.091 11.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 KFH46616.1 - 0.00096 18.2 0.1 0.57 9.2 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_17 PF13207.1 KFH46616.1 - 0.0012 19.6 0.0 2.1 9.1 0.0 3.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KFH46616.1 - 0.0026 17.3 2.0 1.5 8.3 0.1 2.6 3 0 0 3 3 2 2 AAA domain AAA_10 PF12846.2 KFH46616.1 - 0.0039 16.6 1.1 0.78 9.1 0.1 2.5 2 0 0 2 2 2 1 AAA-like domain ArgK PF03308.11 KFH46616.1 - 0.0047 15.7 0.9 2.4 6.8 0.0 2.6 2 0 0 2 2 2 2 ArgK protein AAA_22 PF13401.1 KFH46616.1 - 0.013 15.6 0.6 8.5 6.5 0.0 3.4 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 KFH46616.1 - 0.02 14.6 6.4 0.086 12.6 0.4 2.7 2 0 0 2 2 2 0 Dynamin family AAA_25 PF13481.1 KFH46616.1 - 0.023 14.0 0.0 2.6 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KFH46616.1 - 0.063 13.4 0.2 24 5.1 0.0 3.3 3 0 0 3 3 3 0 RNA helicase FtsK_SpoIIIE PF01580.13 KFH46616.1 - 0.064 12.7 0.1 4.6 6.6 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.4 KFH46616.1 - 0.066 11.8 0.3 3.2 6.2 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain T2SE PF00437.15 KFH46616.1 - 0.09 11.6 0.2 1.5 7.6 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein MobB PF03205.9 KFH46616.1 - 0.16 11.6 1.4 15 5.3 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 KFH46616.1 - 0.21 11.8 6.1 5.3 7.3 0.0 3.6 4 0 0 4 4 4 0 AAA domain ATP_bind_1 PF03029.12 KFH46616.1 - 6.9 6.1 6.0 12 5.3 0.1 2.8 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein Hid1 PF12722.2 KFH46617.1 - 1.4e-250 833.6 0.0 5.7e-250 831.7 0.0 1.7 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 KFH46617.1 - 1.3e-76 258.1 0.0 1.9e-76 257.6 0.0 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein 2-Hacid_dh_C PF02826.14 KFH46618.1 - 4.8e-51 172.4 0.0 8.1e-51 171.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFH46618.1 - 4.3e-15 55.3 0.0 6.1e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KFH46618.1 - 0.00034 20.4 0.0 0.00092 19.0 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase UCH PF00443.24 KFH46619.1 - 1.1e-34 119.7 0.0 1.8e-34 119.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFH46619.1 - 0.00062 19.3 0.0 0.0043 16.5 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2387 PF09526.5 KFH46619.1 - 0.097 12.5 0.4 6.2 6.8 0.0 3.0 3 0 0 3 3 3 0 Probable metal-binding protein (DUF2387) Sec8_exocyst PF04048.9 KFH46620.1 - 7e-49 165.1 1.8 1.5e-48 164.0 0.8 2.0 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 KFH46620.1 - 2e-10 40.0 0.5 3.5e-10 39.2 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Phage_GP20 PF06810.6 KFH46620.1 - 0.032 13.6 0.2 0.09 12.2 0.1 1.7 1 0 0 1 1 1 0 Phage minor structural protein GP20 CTP_transf_1 PF01148.15 KFH46621.1 - 6.2e-06 26.0 8.9 6.2e-06 26.0 6.1 3.5 3 1 0 3 3 3 1 Cytidylyltransferase family TauD PF02668.11 KFH46622.1 - 3.8e-42 144.7 0.0 4.7e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 KFH46622.1 - 0.02 15.4 0.1 0.16 12.5 0.0 2.2 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily CsiD PF08943.5 KFH46622.1 - 0.12 11.2 0.0 0.23 10.3 0.0 1.4 1 0 0 1 1 1 0 CsiD Pkinase PF00069.20 KFH46623.1 - 5.3e-63 212.6 0.0 6.3e-63 212.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH46623.1 - 5.2e-25 88.0 0.0 6.8e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH46623.1 - 1.6e-07 30.5 0.0 6.2e-07 28.6 0.0 1.8 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 KFH46623.1 - 0.00077 19.2 0.0 0.0051 16.5 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF3433 PF11915.3 KFH46624.1 - 1.3e-41 140.6 8.8 8.9e-26 89.8 0.5 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) UPF0546 PF10639.4 KFH46624.1 - 0.019 14.8 1.0 4.1 7.2 0.0 3.1 4 0 0 4 4 4 0 Uncharacterised protein family UPF0546 COMPASS-Shg1 PF05205.7 KFH46625.1 - 3.7e-22 78.6 0.3 3.7e-22 78.6 0.2 1.9 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 Mito_carr PF00153.22 KFH46626.1 - 3.7e-15 55.3 3.2 0.00047 19.8 0.0 5.2 4 1 0 4 4 4 4 Mitochondrial carrier protein AIG2 PF06094.7 KFH46628.1 - 6.3e-18 65.1 0.1 9e-18 64.6 0.1 1.2 1 0 0 1 1 1 1 AIG2-like family SOBP PF15279.1 KFH46629.1 - 3.7 7.8 13.6 7 6.9 9.4 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Ycf1 PF05758.7 KFH46629.1 - 7.6 4.1 14.1 13 3.3 9.7 1.5 1 0 0 1 1 1 0 Ycf1 adh_short PF00106.20 KFH46630.1 - 3.3e-25 88.9 2.1 5.1e-25 88.3 1.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH46630.1 - 1.1e-12 48.2 0.2 2.8e-12 46.9 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH46630.1 - 9.9e-09 35.1 0.9 2e-08 34.1 0.6 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KFH46630.1 - 2.2e-05 23.9 0.0 3.7e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KFH46630.1 - 0.00022 20.9 0.5 0.0015 18.3 0.1 2.3 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 KFH46630.1 - 0.00034 20.6 0.4 0.013 15.5 0.3 2.3 1 1 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 KFH46630.1 - 0.017 14.7 0.2 1.8 8.2 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KFH46630.1 - 0.05 13.7 0.0 0.072 13.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 KFH46630.1 - 0.063 12.1 0.0 0.084 11.7 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ldh_1_N PF00056.18 KFH46630.1 - 0.11 12.2 0.0 0.3 10.8 0.0 1.7 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain EXS PF03124.9 KFH46631.1 - 7.5e-95 317.8 23.8 9.2e-95 317.5 16.5 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 KFH46631.1 - 2.7e-55 188.1 0.1 2.7e-55 188.1 0.1 2.8 2 2 0 2 2 2 1 SPX domain Nucleoplasmin PF03066.10 KFH46631.1 - 0.75 9.3 19.2 0.8 9.2 7.4 2.3 2 0 0 2 2 2 0 Nucleoplasmin Myc_N PF01056.13 KFH46631.1 - 0.75 8.8 13.1 0.82 8.7 3.3 2.4 2 0 0 2 2 2 0 Myc amino-terminal region DDHD PF02862.12 KFH46631.1 - 1.4 8.6 5.9 0.96 9.2 1.1 2.3 2 0 0 2 2 2 0 DDHD domain PBP1_TM PF14812.1 KFH46631.1 - 3.8 7.8 25.7 9 6.6 4.9 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.7 KFH46631.1 - 4.1 6.5 13.1 1.1 8.4 4.3 2.2 2 0 0 2 2 2 0 NOA36 protein Fer2 PF00111.22 KFH46632.1 - 6.1e-14 51.5 0.6 9e-14 50.9 0.4 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NDUF_B7 PF05676.8 KFH46633.1 - 5.5e-33 112.1 4.5 6.9e-33 111.8 3.1 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 KFH46633.1 - 0.00022 20.8 3.0 0.00026 20.6 1.9 1.3 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF2267 PF10025.4 KFH46633.1 - 0.023 14.7 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) Antifungal_prot PF11402.3 KFH46633.1 - 1.1 9.4 5.3 3.2 8.0 3.7 1.8 1 1 0 1 1 1 0 Antifungal protein MFS_1 PF07690.11 KFH46634.1 - 5.2e-30 104.3 26.4 7.9e-30 103.7 18.3 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH46634.1 - 2.6e-09 36.1 14.1 4.2e-09 35.4 9.8 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KFH46634.1 - 1.2e-07 30.3 5.7 1.4e-07 30.0 3.9 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SpoVAB PF13782.1 KFH46634.1 - 0.39 10.7 3.2 3 7.8 0.1 2.7 1 1 0 2 2 2 0 Stage V sporulation protein AB Sugar_tr PF00083.19 KFH46635.1 - 2.1e-95 319.9 17.9 2.4e-95 319.7 12.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH46635.1 - 9.1e-14 50.9 29.3 9.1e-14 50.9 20.3 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF486 PF04342.7 KFH46635.1 - 3.9 7.5 7.7 0.17 11.9 0.6 2.2 3 0 0 3 3 3 0 Protein of unknown function, DUF486 Spore_YtfJ PF09579.5 KFH46636.1 - 0.34 10.7 1.7 0.97 9.3 1.2 1.7 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) GFO_IDH_MocA PF01408.17 KFH46637.1 - 1.6e-23 83.4 0.0 3.2e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 KFH46637.1 - 0.00092 19.5 0.0 0.0016 18.8 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 KFH46637.1 - 0.063 12.2 0.0 0.089 11.7 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase FAD_oxidored PF12831.2 KFH46638.1 - 3.4e-89 299.8 0.0 3.9e-89 299.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 KFH46638.1 - 1.1e-05 24.5 0.0 2.3e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFH46638.1 - 2e-05 23.6 0.7 3.2e-05 22.9 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KFH46638.1 - 4.6e-05 23.3 0.3 0.00017 21.5 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KFH46638.1 - 0.004 16.0 0.4 0.004 16.0 0.3 1.4 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KFH46638.1 - 0.0053 16.6 0.0 0.0082 16.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFH46638.1 - 0.046 13.7 0.1 0.096 12.7 0.1 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFH46638.1 - 0.057 11.8 0.1 0.077 11.4 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 KFH46638.1 - 0.15 12.4 0.1 0.3 11.5 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_6 PF12697.2 KFH46640.1 - 5.8e-22 78.7 0.0 2e-21 76.9 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH46640.1 - 3.2e-06 26.9 0.0 6.1e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family AMP-binding PF00501.23 KFH46641.1 - 3.4e-40 137.7 0.0 4.8e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFH46641.1 - 7.4e-05 23.6 0.1 0.00016 22.5 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short_C2 PF13561.1 KFH46642.1 - 2.2e-30 106.2 0.4 2.6e-30 105.9 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFH46642.1 - 4.2e-28 98.3 3.8 5.3e-28 98.0 2.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH46642.1 - 1.3e-15 57.5 1.9 1.8e-15 57.1 1.4 1.1 1 0 0 1 1 1 1 KR domain Glyco_hydro_1 PF00232.13 KFH46642.1 - 0.049 11.8 0.0 0.062 11.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 NAD_binding_3 PF03447.11 KFH46642.1 - 0.094 13.1 0.6 0.16 12.3 0.4 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Actin PF00022.14 KFH46643.1 - 1.7e-130 434.9 0.0 1.9e-130 434.8 0.0 1.0 1 0 0 1 1 1 1 Actin ATP-synt_ab PF00006.20 KFH46644.1 - 7.8e-112 371.9 0.0 1.2e-111 371.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KFH46644.1 - 3e-19 69.5 0.6 6.7e-19 68.4 0.4 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KFH46644.1 - 1.2e-13 50.9 3.4 2.3e-13 50.1 1.6 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain Peptidase_M23 PF01551.17 KFH46644.1 - 0.068 13.2 0.1 2.3 8.3 0.1 3.3 4 0 0 4 4 4 0 Peptidase family M23 PAT1 PF09770.4 KFH46645.1 - 0.073 11.3 53.2 0.1 10.8 36.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 KFH46645.1 - 0.15 10.2 64.1 0.21 9.7 44.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FPN1 PF06963.7 KFH46646.1 - 6.8e-115 383.8 20.3 8e-115 383.6 14.1 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Pyr_redox_2 PF07992.9 KFH46648.1 - 4.5e-06 26.6 0.8 9.9e-05 22.3 0.6 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFH46648.1 - 0.00044 20.3 0.2 0.0018 18.3 0.1 1.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KFH46648.1 - 0.0029 16.5 0.4 0.0088 14.9 0.2 1.7 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KFH46648.1 - 0.0047 16.7 0.0 0.047 13.4 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pex14_N PF04695.8 KFH46648.1 - 0.023 14.7 1.9 0.067 13.2 0.9 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mito_fiss_reg PF05308.6 KFH46648.1 - 0.075 12.4 11.4 0.11 11.7 7.9 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Malic_M PF03949.10 KFH46648.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain CAP_N PF01213.14 KFH46648.1 - 2 7.6 12.3 3.1 6.9 8.6 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal p450 PF00067.17 KFH46649.1 - 1.4e-48 165.6 0.0 1.9e-48 165.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 WG_beta_rep PF14903.1 KFH46649.1 - 0.13 12.5 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 WG containing repeat EXOSC1 PF10447.4 KFH46650.1 - 6.9e-27 93.2 0.6 1.2e-26 92.5 0.4 1.4 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 KFH46650.1 - 1.7e-11 43.1 0.7 3.8e-11 42.0 0.5 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.18 KFH46650.1 - 0.0079 16.2 0.3 0.079 13.0 0.2 2.2 1 1 0 1 1 1 1 S1 RNA binding domain IF-2B PF01008.12 KFH46651.1 - 1.5e-44 152.1 0.1 3.5e-44 150.8 0.0 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family DUF2710 PF10921.3 KFH46651.1 - 0.048 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2710) SAGA-Tad1 PF12767.2 KFH46651.1 - 1.1 8.9 10.8 1.8 8.1 7.5 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit PAT1 PF09770.4 KFH46651.1 - 9.8 4.2 24.7 13 3.8 17.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3684 PF12449.3 KFH46652.1 - 0 1377.4 0.0 0 1377.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 KFH46652.1 - 3.3e-05 23.5 0.0 7.9e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Na_H_Exchanger PF00999.16 KFH46654.1 - 8e-43 146.4 13.2 1.1e-42 145.9 9.1 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CbiM PF01891.11 KFH46654.1 - 4.6 6.7 11.1 1 8.9 0.0 3.7 4 0 0 4 4 4 0 Cobalt uptake substrate-specific transmembrane region TruB_N PF01509.13 KFH46655.1 - 3.2e-47 160.4 0.0 1.4e-46 158.3 0.0 1.9 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) DUF4334 PF14232.1 KFH46657.1 - 5.7e-25 86.7 0.2 5.7e-25 86.7 0.1 1.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4334) GXWXG PF14231.1 KFH46657.1 - 2.3e-22 78.4 0.1 4.6e-22 77.4 0.0 1.5 2 0 0 2 2 2 1 GXWXG protein UPF0029 PF01205.14 KFH46658.1 - 4.3e-28 97.1 0.0 7.4e-28 96.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 KFH46658.1 - 8.7e-07 28.8 0.0 1.9e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 RWD domain TPT PF03151.11 KFH46659.1 - 9.9e-27 93.4 12.3 9.9e-27 93.4 8.5 2.6 3 1 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 KFH46659.1 - 5.9e-07 28.6 15.5 4e-05 22.6 2.1 2.2 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.15 KFH46659.1 - 0.0001 22.3 33.1 0.01 15.8 8.7 3.0 3 0 0 3 3 3 2 EamA-like transporter family Sulfatase PF00884.18 KFH46660.1 - 0.00016 20.9 0.1 0.0023 17.1 0.0 2.0 1 1 0 1 1 1 1 Sulfatase IGPD PF00475.13 KFH46661.1 - 8.1e-54 181.4 0.6 2.9e-43 147.2 0.0 2.1 2 0 0 2 2 2 2 Imidazoleglycerol-phosphate dehydratase EMP24_GP25L PF01105.19 KFH46662.1 - 1.6e-47 161.5 2.0 1.8e-47 161.4 1.4 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF1510 PF07423.6 KFH46664.1 - 4.2 6.6 7.9 7.3 5.8 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF1875 PF08961.5 KFH46665.1 - 0.037 13.3 1.9 0.044 13.0 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) DUF2554 PF10829.3 KFH46665.1 - 0.19 11.8 1.2 0.26 11.4 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2554) ORC2 PF04084.9 KFH46666.1 - 1.2e-95 320.0 0.0 1.5e-95 319.8 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Nop14 PF04147.7 KFH46666.1 - 1.1 7.0 12.5 1.5 6.6 8.6 1.3 1 0 0 1 1 1 0 Nop14-like family Glyco_hydro_11 PF00457.12 KFH46667.1 - 1.1e-74 249.8 24.6 1.3e-74 249.5 17.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 DUF1754 PF08555.5 KFH46669.1 - 2.5e-15 56.8 16.3 4.3e-15 56.1 11.3 1.3 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) DUF3546 PF12066.3 KFH46669.1 - 1 9.4 7.3 0.16 11.9 1.9 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3546) V_ATPase_I PF01496.14 KFH46669.1 - 1.8 6.3 7.2 2.2 6.0 5.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1978 PF09321.5 KFH46669.1 - 5.1 6.4 14.3 17 4.7 9.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1978) PGA2 PF07543.7 KFH46669.1 - 10 5.9 12.4 13 5.5 8.6 1.1 1 0 0 1 1 1 0 Protein trafficking PGA2 EHN PF06441.7 KFH46670.1 - 5e-17 61.8 0.2 9e-17 61.0 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Nuc_N PF14448.1 KFH46671.1 - 0.048 13.2 0.1 0.12 11.9 0.1 1.6 1 0 0 1 1 1 0 Nuclease N terminal MAP65_ASE1 PF03999.7 KFH46671.1 - 3 6.3 13.7 3.9 5.9 9.5 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF2413 PF10310.4 KFH46671.1 - 3.3 6.4 17.1 3.9 6.1 11.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Pol_alpha_B_N PF08418.5 KFH46671.1 - 6.7 6.1 21.4 9.8 5.6 14.9 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Ndc1_Nup PF09531.5 KFH46671.1 - 8.7 4.6 8.5 8.8 4.6 5.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup adh_short_C2 PF13561.1 KFH46672.1 - 2.2e-22 80.0 1.1 2.7e-22 79.6 0.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFH46672.1 - 1.1e-20 74.1 1.8 2e-20 73.3 1.3 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH46672.1 - 1.7e-07 31.0 0.8 3.1e-07 30.2 0.6 1.5 1 1 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 KFH46672.1 - 0.012 14.7 0.0 0.02 14.0 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KFH46672.1 - 0.068 12.9 0.8 0.14 11.8 0.3 1.7 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pentaxin PF00354.12 KFH46672.1 - 0.089 12.2 0.1 0.17 11.2 0.0 1.5 2 0 0 2 2 2 0 Pentaxin family 3HCDH_N PF02737.13 KFH46672.1 - 0.46 10.1 2.6 0.34 10.5 0.4 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MIF4G_like PF09088.6 KFH46673.1 - 4.4e-78 261.1 0.0 7.1e-78 260.4 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 KFH46673.1 - 1.2e-46 159.0 0.0 1.6e-46 158.6 0.0 1.2 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 KFH46673.1 - 0.17 11.2 0.0 0.53 9.6 0.0 1.8 2 0 0 2 2 2 0 MIF4G domain adh_short PF00106.20 KFH46674.1 - 4.6e-16 59.1 0.9 7e-16 58.5 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KFH46674.1 - 4.5e-09 36.2 0.1 2.3e-08 33.8 0.0 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KFH46674.1 - 0.0011 18.4 0.0 0.0038 16.6 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KFH46674.1 - 0.0019 17.1 0.0 0.0032 16.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 KFH46674.1 - 0.012 15.6 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 KFH46674.1 - 0.047 13.6 0.1 0.19 11.7 0.1 2.0 1 1 0 1 1 1 0 NADH(P)-binding SMI1_KNR4 PF09346.5 KFH46675.1 - 5.1e-34 117.0 0.0 1.1e-33 116.0 0.0 1.6 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) AA_permease_2 PF13520.1 KFH46676.1 - 9.7e-67 225.3 36.0 1.3e-66 224.9 25.0 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFH46676.1 - 3.7e-34 117.8 23.3 3.7e-34 117.8 16.1 2.3 2 1 0 2 2 2 1 Amino acid permease Chitin_bind_3 PF03067.10 KFH46677.1 - 1.3e-07 32.0 0.0 2.3e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Chitin binding domain Glyco_hydro_61 PF03443.9 KFH46677.1 - 0.0011 18.8 0.1 0.0023 17.7 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4625 PF15418.1 KFH46677.1 - 0.07 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) MMtag PF10159.4 KFH46678.1 - 1.4e-28 98.7 3.1 1.4e-28 98.7 2.1 3.0 2 1 1 3 3 3 1 Kinase phosphorylation protein FAT PF02259.18 KFH46680.1 - 3.5e-75 253.1 0.8 6.8e-75 252.2 0.6 1.5 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 KFH46680.1 - 1.2e-25 90.3 0.3 7.8e-25 87.7 0.1 2.4 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 KFH46680.1 - 2.1e-08 33.4 0.1 5.2e-08 32.1 0.1 1.7 1 0 0 1 1 1 1 FATC domain TPR_2 PF07719.12 KFH46680.1 - 0.0023 17.7 3.1 0.2 11.6 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_32 PF13654.1 KFH46680.1 - 0.0068 15.1 0.6 0.017 13.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain HEAT_2 PF13646.1 KFH46680.1 - 0.013 15.7 1.0 40 4.5 0.0 5.5 6 0 0 6 6 6 0 HEAT repeats TPR_8 PF13181.1 KFH46680.1 - 0.043 13.6 5.4 1.6 8.6 0.5 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFH46680.1 - 0.057 13.0 4.6 1.5 8.5 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFH46680.1 - 2.4 7.8 9.7 12 5.6 0.1 3.6 3 0 0 3 3 3 0 TPR repeat Rrp15p PF07890.7 KFH46681.1 - 6.1e-36 123.3 10.2 6.1e-36 123.3 7.1 2.4 3 0 0 3 3 3 1 Rrp15p FHA PF00498.21 KFH46682.1 - 1.1e-05 25.4 0.0 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 FHA domain Peptidase_S10 PF00450.17 KFH46683.1 - 1.3e-132 442.8 0.2 1.7e-132 442.5 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 KFH46683.1 - 1.2e-05 25.4 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Abhydrolase_6 PF12697.2 KFH46683.1 - 0.0011 18.8 0.0 0.016 15.0 0.0 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family MFS_1 PF07690.11 KFH46684.1 - 0.2 10.3 13.8 0.16 10.6 8.5 1.5 2 0 0 2 2 2 0 Major Facilitator Superfamily SKG6 PF08693.5 KFH46684.1 - 1.2 8.4 4.1 0.37 10.1 0.1 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain TatC PF00902.13 KFH46684.1 - 1.6 8.0 6.3 0.94 8.8 2.6 1.8 2 1 0 2 2 2 0 Sec-independent protein translocase protein (TatC) Peptidase_M18 PF02127.10 KFH46685.1 - 5.8e-125 417.1 0.0 6.8e-125 416.9 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) TSC22 PF01166.13 KFH46686.1 - 0.00014 21.7 10.4 0.044 13.7 0.6 4.7 1 1 4 5 5 5 1 TSC-22/dip/bun family CCDC155 PF14662.1 KFH46686.1 - 0.00046 19.8 18.2 0.0026 17.3 8.3 2.4 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 Filament PF00038.16 KFH46686.1 - 0.00072 19.1 16.2 0.0014 18.1 11.3 1.5 1 0 0 1 1 1 1 Intermediate filament protein Cep57_CLD_2 PF14197.1 KFH46686.1 - 0.0015 18.4 9.7 0.0015 18.4 6.7 3.4 2 1 2 4 4 4 1 Centrosome localisation domain of PPC89 DUF2968 PF11180.3 KFH46686.1 - 0.0017 17.7 8.6 0.0017 17.7 6.0 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF2968) TACC PF05010.9 KFH46686.1 - 0.003 17.3 13.2 0.085 12.6 9.2 2.2 1 1 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC) bZIP_1 PF00170.16 KFH46686.1 - 0.0042 17.0 17.0 0.66 9.9 0.0 4.3 2 2 2 4 4 4 2 bZIP transcription factor FAM92 PF06730.6 KFH46686.1 - 0.016 14.5 5.0 0.033 13.5 3.0 1.8 1 1 1 2 2 2 0 FAM92 protein Apolipoprotein PF01442.13 KFH46686.1 - 0.016 14.7 11.6 0.019 14.5 7.2 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain FadA PF09403.5 KFH46686.1 - 0.017 15.1 6.7 0.017 15.1 4.7 1.9 1 1 0 1 1 1 0 Adhesion protein FadA HAP1_N PF04849.8 KFH46686.1 - 0.02 13.8 15.5 0.026 13.4 10.3 1.5 1 1 0 1 1 1 0 HAP1 N-terminal conserved region DUF904 PF06005.7 KFH46686.1 - 0.025 14.8 18.8 0.88 9.9 3.8 4.5 3 1 2 5 5 4 0 Protein of unknown function (DUF904) CENP-F_leu_zip PF10473.4 KFH46686.1 - 0.037 13.9 19.6 0.15 11.8 8.3 2.7 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3708 PF12501.3 KFH46686.1 - 0.058 13.2 0.7 0.13 12.1 0.3 1.6 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter ADIP PF11559.3 KFH46686.1 - 0.067 13.0 17.5 0.17 11.8 6.2 2.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Bacillus_HBL PF05791.6 KFH46686.1 - 0.11 11.8 1.4 0.29 10.5 0.5 1.9 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) GAS PF13851.1 KFH46686.1 - 0.12 11.5 15.3 0.62 9.2 7.6 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DivIC PF04977.10 KFH46686.1 - 0.13 11.7 13.2 0.15 11.5 1.4 4.0 1 1 3 4 4 4 0 Septum formation initiator DUF1932 PF09130.6 KFH46686.1 - 0.19 11.4 3.2 0.77 9.5 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1932) ATG16 PF08614.6 KFH46686.1 - 0.23 11.2 16.0 1.4 8.7 11.1 2.1 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Rab5-bind PF09311.6 KFH46686.1 - 0.26 11.1 18.4 11 5.8 12.7 2.4 1 1 0 1 1 1 0 Rabaptin-like protein NYD-SP28_assoc PF14775.1 KFH46686.1 - 0.28 10.8 11.3 0.97 9.1 0.2 4.0 3 1 0 4 4 4 0 Sperm tail C-terminal domain TBPIP PF07106.8 KFH46686.1 - 0.35 10.4 12.1 0.31 10.5 4.4 2.5 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1664 PF07889.7 KFH46686.1 - 0.35 10.6 1.5 1.2 8.9 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF3450 PF11932.3 KFH46686.1 - 0.36 10.0 7.4 0.81 8.8 3.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) HALZ PF02183.13 KFH46686.1 - 0.44 10.2 19.1 0.55 9.9 0.1 4.2 5 1 0 5 5 3 0 Homeobox associated leucine zipper DUF972 PF06156.8 KFH46686.1 - 0.53 10.6 21.8 0.64 10.3 1.0 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF972) TMF_DNA_bd PF12329.3 KFH46686.1 - 0.53 10.1 10.5 1.3 8.8 2.3 3.4 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding Rootletin PF15035.1 KFH46686.1 - 0.57 10.1 23.9 11 5.9 16.4 2.3 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion IncA PF04156.9 KFH46686.1 - 0.65 9.5 23.2 0.39 10.2 6.6 2.7 1 1 2 3 3 3 0 IncA protein DUF2937 PF11157.3 KFH46686.1 - 0.69 9.2 3.4 8.8 5.6 1.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) TMF_TATA_bd PF12325.3 KFH46686.1 - 0.92 9.2 14.0 0.98 9.1 4.4 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF342 PF03961.8 KFH46686.1 - 1.2 7.4 3.1 1.5 7.1 1.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 KFH46686.1 - 1.6 6.5 10.1 1.9 6.2 6.6 1.5 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Jnk-SapK_ap_N PF09744.4 KFH46686.1 - 1.8 8.5 20.8 0.06 13.3 8.9 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Tropomyosin_1 PF12718.2 KFH46686.1 - 2.4 7.9 18.5 4 7.2 11.1 2.5 1 1 0 1 1 1 0 Tropomyosin like KLRAQ PF10205.4 KFH46686.1 - 2.4 8.2 11.5 1.4 9.0 2.1 3.3 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein Mnd1 PF03962.10 KFH46686.1 - 2.9 7.5 17.0 5.5 6.5 7.0 2.3 1 1 1 2 2 2 0 Mnd1 family DivIVA PF05103.8 KFH46686.1 - 3.4 7.7 11.6 2.4 8.2 4.2 2.5 1 1 1 2 2 2 0 DivIVA protein DUF4140 PF13600.1 KFH46686.1 - 7.5 7.0 11.5 22 5.5 5.3 2.8 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) bZIP_2 PF07716.10 KFH46686.1 - 9.6 6.1 21.9 2.6 7.9 2.7 4.5 4 1 0 4 4 4 0 Basic region leucine zipper Pro_isomerase PF00160.16 KFH46687.1 - 1.2e-33 116.5 0.0 1.7e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Fungal_trans PF04082.13 KFH46688.1 - 4.5e-16 58.5 0.5 8.3e-16 57.6 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH46688.1 - 2.6e-07 30.4 8.2 5.4e-07 29.4 5.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol_Rpb2_6 PF00562.23 KFH46689.1 - 1e-116 389.8 0.0 1.6e-116 389.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KFH46689.1 - 1.5e-50 171.0 0.5 2.9e-50 170.0 0.1 1.6 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 KFH46689.1 - 1.2e-29 102.4 0.2 2.9e-29 101.1 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 KFH46689.1 - 5.5e-29 100.9 0.2 1.1e-28 99.9 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 KFH46689.1 - 2.3e-21 75.3 0.0 4.4e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 KFH46689.1 - 5.8e-20 70.8 0.2 1.4e-19 69.6 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 KFH46689.1 - 2.2e-12 46.7 1.0 5.1e-12 45.5 0.7 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 DUF3318 PF11780.3 KFH46691.1 - 0.045 13.3 0.8 0.089 12.3 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) Nop14 PF04147.7 KFH46691.1 - 0.13 10.1 0.7 0.19 9.6 0.5 1.2 1 0 0 1 1 1 0 Nop14-like family DUF2470 PF10615.4 KFH46692.1 - 2.1e-18 66.2 0.0 3e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Abi PF02517.11 KFH46692.1 - 0.045 13.8 0.9 0.066 13.3 0.7 1.3 1 0 0 1 1 1 0 CAAX protease self-immunity PIGA PF08288.7 KFH46693.1 - 6.8e-48 160.9 1.3 6.8e-48 160.9 0.9 2.1 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 KFH46693.1 - 1.8e-29 102.3 0.0 3.1e-29 101.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KFH46693.1 - 9.3e-15 54.9 0.0 2.1e-14 53.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KFH46693.1 - 3.8e-12 46.6 0.0 7.9e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 KFH46693.1 - 1.8e-10 40.7 0.4 3.8e-10 39.7 0.2 1.6 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_2 PF13477.1 KFH46693.1 - 2.3e-06 27.4 0.3 3.9e-06 26.7 0.2 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 KFH46693.1 - 0.00051 20.2 0.0 0.0019 18.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 MFS_1 PF07690.11 KFH46695.1 - 5e-32 110.9 56.7 1.3e-28 99.7 33.2 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFH46695.1 - 2.8e-08 32.4 19.5 9.4e-08 30.7 6.4 2.2 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Herpes_UL43 PF05072.8 KFH46695.1 - 0.88 8.2 6.3 0.69 8.5 1.5 2.2 2 0 0 2 2 2 0 Herpesvirus UL43 protein Helicase_C PF00271.26 KFH46696.1 - 1.7e-20 72.6 0.0 8.5e-17 60.7 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 KFH46696.1 - 9.6e-05 21.9 0.0 0.00021 20.8 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase WD40 PF00400.27 KFH46697.1 - 1.2e-13 50.3 19.5 0.00011 21.9 0.0 8.6 10 1 0 10 10 10 4 WD domain, G-beta repeat PQQ_3 PF13570.1 KFH46697.1 - 0.32 11.3 6.0 6.4 7.2 0.0 4.4 4 0 0 4 4 4 0 PQQ-like domain Ribosomal_S6e PF01092.14 KFH46698.1 - 9.3e-61 203.0 0.5 1.8e-60 202.1 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e HSP70 PF00012.15 KFH46699.1 - 1.2e-269 895.3 4.9 1.4e-269 895.1 3.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFH46699.1 - 1.8e-17 62.9 0.0 3.1e-16 58.9 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 KFH46699.1 - 0.001 18.7 0.0 0.0028 17.3 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 KFH46699.1 - 0.012 14.7 0.1 0.056 12.5 0.0 2.0 1 1 1 2 2 2 0 Hydantoinase/oxoprolinase FtsA PF14450.1 KFH46699.1 - 0.024 14.4 3.2 1.6 8.6 0.1 3.2 2 2 0 2 2 2 0 Cell division protein FtsA StbA PF06406.6 KFH46699.1 - 0.064 12.1 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 StbA protein PMBR PF09373.5 KFH46699.1 - 0.32 11.0 1.2 0.63 10.0 0.0 2.2 2 0 0 2 2 2 0 Pseudomurein-binding repeat DUF3918 PF13056.1 KFH46700.1 - 0.14 11.5 0.1 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) GCN5L1 PF06320.8 KFH46701.1 - 7.6e-08 32.2 1.0 1.1e-07 31.7 0.7 1.2 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) CCDC155 PF14662.1 KFH46701.1 - 0.077 12.5 2.2 0.1 12.1 1.6 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 HAUS6_N PF14661.1 KFH46701.1 - 0.16 11.2 2.2 0.21 10.9 1.5 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus RSN1_TM PF13967.1 KFH46702.1 - 0.053 13.0 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport RNA12 PF10443.4 KFH46703.1 - 8.2e-159 528.7 2.0 1.6e-158 527.7 0.1 1.9 2 0 0 2 2 2 1 RNA12 protein RRM_1 PF00076.17 KFH46703.1 - 1.6e-06 27.6 0.0 7.4e-06 25.5 0.0 2.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arch_ATPase PF01637.13 KFH46703.1 - 2.2e-05 24.2 0.1 0.00014 21.6 0.0 2.1 1 1 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 KFH46703.1 - 0.006 16.5 0.1 0.05 13.5 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain PPTA PF01239.17 KFH46703.1 - 0.01 15.1 0.1 0.029 13.7 0.1 1.8 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat DUF2487 PF10673.4 KFH46703.1 - 0.044 13.5 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) HR1 PF02185.11 KFH46703.1 - 0.43 10.3 3.7 0.93 9.2 2.6 1.6 1 0 0 1 1 1 0 Hr1 repeat DUF2029 PF09594.5 KFH46705.1 - 0.023 14.2 0.7 0.024 14.1 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) Ribosomal_S5_C PF03719.10 KFH46706.1 - 8.2e-13 47.4 0.0 2.7e-12 45.7 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 KFH46706.1 - 8.2e-11 41.4 0.0 1.5e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain RNA_pol_Rpb1_6 PF04992.9 KFH46706.1 - 10 5.8 7.3 0.26 11.0 0.2 1.9 3 0 0 3 3 3 0 RNA polymerase Rpb1, domain 6 Ribosomal_S8e PF01201.17 KFH46707.1 - 2e-48 163.8 2.5 2.7e-48 163.4 1.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S8e DUF1682 PF07946.9 KFH46707.1 - 0.034 12.9 0.2 0.043 12.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) SMAP PF15477.1 KFH46707.1 - 0.14 12.4 5.7 0.81 10.0 4.0 2.3 1 1 1 2 2 2 0 Small acidic protein family Nfu_N PF08712.6 KFH46709.1 - 4.5e-27 93.5 0.0 1.7e-26 91.6 0.0 1.9 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 KFH46709.1 - 1.5e-21 75.8 0.0 2.5e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.4 KFH46709.1 - 0.013 15.3 0.6 0.033 14.0 0.2 1.8 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus CENP-F_leu_zip PF10473.4 KFH46710.1 - 0.002 18.0 16.3 0.002 18.0 11.3 8.3 6 2 3 10 10 10 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lip_prot_lig_C PF10437.4 KFH46710.1 - 0.17 11.5 5.0 29 4.4 0.0 5.1 4 0 0 4 4 4 0 Bacterial lipoate protein ligase C-terminus Met_10 PF02475.11 KFH46711.1 - 0.00026 20.6 0.0 0.0005 19.7 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 KFH46711.1 - 0.013 15.5 0.2 0.024 14.6 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain GDPD PF03009.12 KFH46713.1 - 4.9e-60 203.1 0.0 1.5e-59 201.6 0.0 1.9 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 KFH46713.1 - 8.7e-31 106.1 1.3 4e-10 39.8 0.1 4.7 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFH46713.1 - 1.1e-30 105.3 3.6 1.5e-11 44.4 0.1 5.8 5 0 0 5 5 5 4 Ankyrin repeats (many copies) SPX PF03105.14 KFH46713.1 - 2.6e-26 93.0 5.8 5e-15 56.0 0.5 3.8 2 1 1 3 3 3 2 SPX domain Ank PF00023.25 KFH46713.1 - 4.7e-25 86.0 7.3 3.3e-07 29.7 0.1 6.7 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 KFH46713.1 - 6.4e-23 80.2 3.2 6e-07 29.5 0.0 5.9 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFH46713.1 - 5.1e-16 57.1 4.7 6.4e-05 22.8 0.0 7.4 7 0 0 7 7 7 3 Ankyrin repeat ORC6 PF05460.8 KFH46714.1 - 1.7e-35 122.8 0.0 2.9e-35 122.0 0.0 1.4 1 1 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) WW PF00397.21 KFH46715.1 - 6e-08 32.4 0.2 1.2e-07 31.4 0.2 1.5 1 0 0 1 1 1 1 WW domain DUF3295 PF11702.3 KFH46716.1 - 0.018 14.0 0.1 0.034 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Tetraspannin PF00335.15 KFH46718.1 - 6.2e-07 28.9 0.0 1.5e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 Tetraspanin family zf-HIT PF04438.11 KFH46719.1 - 5e-10 38.8 13.1 7.5e-10 38.2 9.1 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.13 KFH46719.1 - 9.8e-05 22.1 7.8 0.00015 21.5 5.4 1.3 1 0 0 1 1 1 1 MYND finger Neugrin PF06413.6 KFH46720.1 - 4.6e-10 39.6 1.2 4.6e-10 39.6 0.8 2.3 2 0 0 2 2 2 1 Neugrin MRP-L20 PF12824.2 KFH46720.1 - 2.9e-05 24.1 6.8 2.9e-05 24.1 4.7 2.7 2 1 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 Ctf8 PF09696.5 KFH46721.1 - 1.4e-29 102.3 0.0 1.8e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Ctf8 Cm_res_leader PF08077.6 KFH46721.1 - 0.016 14.9 1.2 1.2 8.9 0.4 2.4 2 0 0 2 2 2 0 Chloramphenicol resistance gene leader peptide Smg4_UPF3 PF03467.10 KFH46722.1 - 6.1e-32 111.0 0.0 2e-31 109.3 0.0 1.9 1 1 0 1 1 1 1 Smg-4/UPF3 family RRM_6 PF14259.1 KFH46722.1 - 9e-09 35.1 0.0 1.3e-07 31.4 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFH46722.1 - 5.8e-08 32.2 0.0 2.1e-06 27.2 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH46722.1 - 0.00028 20.6 0.9 0.00058 19.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arrestin_C PF02752.17 KFH46723.1 - 6.4e-16 58.7 0.0 7.2e-15 55.2 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain CENP-C_C PF11699.3 KFH46724.1 - 9.4e-33 112.0 0.2 1.4e-32 111.4 0.1 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.1 KFH46724.1 - 4.3e-24 85.6 11.8 4.3e-24 85.6 8.2 3.6 2 1 1 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.6 KFH46724.1 - 1.1e-06 28.0 0.0 2.5e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Cupin domain DUF2236 PF09995.4 KFH46725.1 - 7.7e-30 103.9 6.1 1.1e-29 103.4 4.3 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) TRF PF08558.5 KFH46726.1 - 2.4e-07 30.3 0.0 4.1e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 KFH46726.1 - 1.3e-05 25.1 0.0 3.1e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFH46726.1 - 0.067 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain RHD3 PF05879.7 KFH46727.1 - 0 1045.9 0.0 0 1045.6 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 KFH46727.1 - 1.8e-08 33.7 0.1 2.9e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 KFH46727.1 - 1.2e-06 28.4 0.0 2.1e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 KFH46727.1 - 4.1e-05 24.0 0.0 7.8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 KFH46727.1 - 6.2e-05 23.0 0.0 0.00017 21.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 KFH46727.1 - 7.3e-05 22.7 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.13 KFH46727.1 - 0.024 13.6 0.1 0.039 12.9 0.0 1.3 1 0 0 1 1 1 0 Septin Cys_Met_Meta_PP PF01053.15 KFH46727.1 - 0.11 10.7 0.0 0.17 10.0 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF3693 PF12472.3 KFH46727.1 - 0.13 11.8 0.3 0.99 9.0 0.0 2.4 2 0 0 2 2 2 0 Phage related protein Mito_carr PF00153.22 KFH46728.1 - 2.7e-30 103.9 0.9 5e-15 54.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-C2H2 PF00096.21 KFH46729.1 - 0.0021 18.2 0.4 0.0085 16.3 0.3 2.1 1 0 0 1 1 1 1 Zinc finger, C2H2 type Pkinase PF00069.20 KFH46730.1 - 2.5e-07 30.1 0.0 6.5e-07 28.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH46730.1 - 1e-05 24.7 0.0 0.00023 20.3 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase DUF4485 PF14846.1 KFH46730.1 - 0.49 10.1 2.5 23 4.8 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4485) Tubulin PF00091.20 KFH46731.1 - 5.1e-70 235.6 0.0 6.8e-70 235.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFH46731.1 - 3.8e-47 159.4 0.0 6.3e-47 158.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KFH46731.1 - 0.0037 16.7 0.0 0.0092 15.4 0.0 1.6 2 0 0 2 2 2 1 Tubulin domain Ribosomal_L15e PF00827.12 KFH46732.1 - 4e-91 303.7 11.3 4.6e-91 303.5 7.9 1.0 1 0 0 1 1 1 1 Ribosomal L15 Codanin-1_C PF15296.1 KFH46732.1 - 0.031 14.1 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 Codanin-1 C-terminus zf-ZPR1 PF03367.8 KFH46733.1 - 1.1e-105 349.7 0.0 5e-54 181.8 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zinc-ribbons_6 PF07191.7 KFH46733.1 - 1.4 8.7 5.1 9.8 6.0 0.3 2.7 3 0 0 3 3 3 0 zinc-ribbons Lar_restr_allev PF14354.1 KFH46733.1 - 1.7 8.9 7.4 0.32 11.3 0.6 2.8 2 1 0 2 2 2 0 Restriction alleviation protein Lar Peptidase_M16_C PF05193.16 KFH46734.1 - 7.6e-18 64.8 0.0 1.6e-17 63.7 0.0 1.5 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KFH46734.1 - 3.8e-17 62.4 0.1 7.1e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) DUF2922 PF11148.3 KFH46734.1 - 0.11 12.1 0.1 0.32 10.6 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2922) tRNA_int_end_N2 PF12928.2 KFH46736.1 - 8.5e-17 60.3 0.0 1.4e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 KFH46736.1 - 0.0053 16.2 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Diphthamide_syn PF01866.12 KFH46738.1 - 2.1e-111 372.0 0.0 2.5e-111 371.8 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein DUF3425 PF11905.3 KFH46739.1 - 1.8e-24 86.1 0.2 3.2e-24 85.3 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KFH46739.1 - 0.058 13.3 2.2 0.11 12.4 1.6 1.5 1 0 0 1 1 1 0 bZIP transcription factor CFEM PF05730.6 KFH46741.1 - 9.3e-12 44.5 9.8 1.5e-11 43.9 6.8 1.3 1 0 0 1 1 1 1 CFEM domain SymE_toxin PF08845.5 KFH46741.1 - 0.02 14.7 0.0 0.057 13.2 0.0 1.7 2 0 0 2 2 2 0 Toxin SymE, type I toxin-antitoxin system DUF4013 PF13197.1 KFH46741.1 - 4.8 6.4 21.3 0.078 12.3 4.0 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF4013) Rad51 PF08423.6 KFH46742.1 - 1.5e-24 86.3 0.0 2.1e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KFH46742.1 - 8.6e-13 48.1 0.0 1.5e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 KFH46742.1 - 6.8e-06 25.3 0.9 0.00019 20.6 0.6 2.1 1 1 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 KFH46742.1 - 0.0002 20.5 0.1 0.00035 19.7 0.1 1.5 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.1 KFH46742.1 - 0.076 13.1 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KFH46742.1 - 0.12 11.9 0.1 0.37 10.4 0.1 1.8 1 1 0 1 1 1 0 NACHT domain Pex14_N PF04695.8 KFH46742.1 - 6.5 6.7 9.9 4.2 7.4 1.6 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mito_fiss_reg PF05308.6 KFH46742.1 - 6.7 6.0 19.3 7.5 5.8 6.7 2.4 2 0 0 2 2 2 0 Mitochondrial fission regulator Miro PF08477.8 KFH46743.1 - 2.1e-13 50.7 0.0 3.3e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 KFH46743.1 - 0.0018 17.5 0.0 0.0038 16.4 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KFH46743.1 - 0.0032 17.3 0.2 0.0091 15.9 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 KFH46743.1 - 0.0067 16.7 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter Ras PF00071.17 KFH46743.1 - 0.01 15.2 0.0 0.035 13.4 0.0 1.7 1 1 0 1 1 1 0 Ras family AAA_29 PF13555.1 KFH46743.1 - 0.016 14.7 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain TrwB_AAD_bind PF10412.4 KFH46743.1 - 0.041 12.5 0.0 0.057 12.0 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.1 KFH46743.1 - 0.042 13.9 0.0 0.14 12.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain IIGP PF05049.8 KFH46743.1 - 0.049 12.4 0.0 0.069 11.9 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.13 KFH46743.1 - 0.052 13.0 0.0 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family MobB PF03205.9 KFH46743.1 - 0.1 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KFH46743.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 KFH46743.1 - 0.13 13.0 0.0 0.19 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rpr2 PF04032.11 KFH46744.1 - 2.6e-12 46.4 0.1 2.6e-12 46.4 0.1 1.7 2 1 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF4230 PF14014.1 KFH46744.1 - 0.053 13.3 0.6 0.074 12.9 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4230) DUF3133 PF11331.3 KFH46744.1 - 0.21 11.1 1.5 20 4.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) DUF1178 PF06676.6 KFH46744.1 - 0.27 11.4 9.8 0.23 11.6 4.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1178) Carn_acyltransf PF00755.15 KFH46746.1 - 4.1e-157 523.8 0.0 2e-141 471.9 0.0 2.1 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase Taeniidae_ag PF05596.6 KFH46746.1 - 0.033 14.0 0.0 4.3 7.2 0.0 2.5 2 0 0 2 2 2 0 Taeniidae antigen DUF913 PF06025.7 KFH46747.1 - 5.6e-103 344.6 0.0 5.6e-103 344.6 0.0 3.4 3 0 0 3 3 3 1 Domain of Unknown Function (DUF913) HECT PF00632.20 KFH46747.1 - 2.2e-97 326.0 0.1 3.6e-97 325.3 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 KFH46747.1 - 3.1e-86 289.6 2.8 7.3e-86 288.4 0.0 3.1 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 KFH46747.1 - 9.1e-29 99.5 3.8 9.1e-29 99.5 2.7 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4414) SOG2 PF10428.4 KFH46748.1 - 3.4e-93 312.7 0.0 3.4e-93 312.7 0.0 3.2 4 0 0 4 4 4 1 RAM signalling pathway protein LRR_8 PF13855.1 KFH46748.1 - 2.1e-20 72.2 10.0 1.1e-09 37.8 0.1 2.9 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KFH46748.1 - 6.3e-18 63.9 3.9 3.2e-08 33.0 0.3 4.9 4 2 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFH46748.1 - 3.4e-12 44.6 2.2 0.068 13.2 0.0 6.5 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_7 PF13504.1 KFH46748.1 - 3.3e-07 29.4 2.1 11 6.7 0.0 5.8 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 KFH46748.1 - 0.00022 20.9 4.4 1.9 8.8 0.0 5.4 5 0 0 5 5 5 2 Leucine Rich repeat DEAD PF00270.24 KFH46749.1 - 1.2e-33 116.0 0.0 2.2e-17 63.0 0.0 2.3 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KFH46749.1 - 2.5e-21 75.3 0.0 4.9e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFH46749.1 - 4.1e-07 30.0 0.0 4.1e-07 30.0 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 KFH46749.1 - 0.0024 16.3 0.0 0.005 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) UvrD-helicase PF00580.16 KFH46749.1 - 0.18 11.0 0.0 0.18 11.0 0.0 2.5 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain Aldose_epim PF01263.15 KFH46750.1 - 5e-49 167.0 1.0 6.6e-49 166.6 0.7 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase CHB_HEX_C_1 PF13290.1 KFH46750.1 - 0.011 15.5 8.4 0.54 10.0 2.1 3.2 2 1 0 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain CHB_HEX_C PF03174.8 KFH46750.1 - 2 8.3 5.1 6.3 6.7 0.8 2.9 1 1 1 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.1 KFH46750.1 - 2.2 8.4 5.7 2.1 8.5 1.1 2.5 2 1 0 2 2 2 0 Fn3 associated EzrA PF06160.7 KFH46752.1 - 0.0034 15.6 3.9 0.0049 15.1 2.7 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA TPR_MLP1_2 PF07926.7 KFH46752.1 - 0.0079 15.9 9.8 0.0079 15.9 6.8 2.6 2 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein Mating_N PF12731.2 KFH46752.1 - 0.04 13.7 0.3 0.08 12.8 0.2 1.5 1 0 0 1 1 1 0 Mating-type protein beta 1 Laminin_II PF06009.7 KFH46752.1 - 0.083 12.6 3.3 0.14 11.8 2.3 1.4 1 1 0 1 1 1 0 Laminin Domain II UPF0242 PF06785.6 KFH46752.1 - 0.29 9.7 3.4 0.44 9.1 2.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) FTO_CTD PF12934.2 KFH46752.1 - 0.66 9.5 6.4 1.6 8.2 1.4 2.2 1 1 1 2 2 2 0 FTO C-terminal domain DUF2353 PF09789.4 KFH46752.1 - 1.2 8.2 12.8 1.2 8.2 4.9 2.3 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) V_ATPase_I PF01496.14 KFH46752.1 - 2.6 5.7 5.3 3.2 5.5 3.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AATF-Che1 PF13339.1 KFH46752.1 - 4.3 7.4 13.1 84 3.3 9.1 2.2 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor AAA_27 PF13514.1 KFH46752.1 - 5.8 4.4 19.0 0.019 12.7 5.9 1.7 1 1 0 2 2 2 0 AAA domain Steroid_dh PF02544.11 KFH46753.1 - 1.9e-30 105.6 0.5 2.8e-30 105.0 0.1 1.4 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 KFH46753.1 - 0.00021 20.6 0.3 0.00051 19.4 0.1 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) Bromodomain PF00439.20 KFH46754.1 - 1.5e-10 40.8 0.0 3e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Bromodomain DUF3128 PF11326.3 KFH46755.1 - 9.6e-27 92.9 0.9 1.8e-26 92.0 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) KAR9 PF08580.5 KFH46755.1 - 0.0069 14.7 2.0 0.0062 14.8 1.4 1.0 1 0 0 1 1 1 1 Yeast cortical protein KAR9 NDUF_B7 PF05676.8 KFH46755.1 - 0.11 11.9 0.4 0.48 9.8 0.0 2.1 1 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) PUF PF00806.14 KFH46756.1 - 2.5e-58 190.3 13.3 1.7e-07 30.3 0.0 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat TylF PF05711.6 KFH46756.1 - 0.004 16.2 0.1 0.0076 15.3 0.1 1.4 1 0 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) BRE1 PF08647.6 KFH46756.1 - 0.1 12.5 3.0 0.22 11.5 2.1 1.5 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF4546 PF15079.1 KFH46757.1 - 0.082 12.0 0.0 0.21 10.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4546) Rgp1 PF08737.5 KFH46758.1 - 1.6e-118 396.3 0.0 6.1e-117 391.2 0.0 2.8 3 0 0 3 3 3 1 Rgp1 Arrestin_N PF00339.24 KFH46758.1 - 0.06 13.1 1.4 0.1 12.4 0.0 2.1 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Epimerase PF01370.16 KFH46759.1 - 9.8e-20 70.9 0.0 1.4e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFH46759.1 - 2e-14 52.9 0.0 2.9e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KFH46759.1 - 5e-13 48.5 0.0 9.2e-13 47.6 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KFH46759.1 - 1.3e-11 44.8 0.1 2.3e-11 44.0 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KFH46759.1 - 3.2e-08 33.6 0.1 7.3e-08 32.5 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KFH46759.1 - 7.1e-07 28.4 0.0 9.8e-07 27.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 KFH46759.1 - 4.2e-05 23.2 0.0 7.1e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 KFH46759.1 - 0.00026 21.3 0.0 0.00063 20.1 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.8 KFH46759.1 - 0.0041 16.4 0.0 0.045 13.0 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family Zeta_toxin PF06414.7 KFH46759.1 - 0.061 12.4 0.0 0.098 11.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin UPF0542 PF15086.1 KFH46760.1 - 0.018 14.7 0.1 0.022 14.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 RabGAP-TBC PF00566.13 KFH46761.1 - 1.9e-47 161.5 0.6 1.9e-47 161.5 0.4 2.5 2 1 0 2 2 2 1 Rab-GTPase-TBC domain Microtub_assoc PF07989.6 KFH46761.1 - 0.2 11.4 21.5 0.24 11.2 3.7 3.4 2 1 1 3 3 3 0 Microtubule associated Z1 PF10593.4 KFH46761.1 - 1.2 8.3 7.2 2.5 7.2 5.0 1.6 1 0 0 1 1 1 0 Z1 domain ADIP PF11559.3 KFH46761.1 - 1.6 8.6 38.9 0.34 10.8 8.1 3.3 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding CCDC155 PF14662.1 KFH46761.1 - 4.2 6.9 39.1 0.56 9.7 7.5 3.0 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 ATP-synt_ab PF00006.20 KFH46762.1 - 6.5e-60 202.2 0.0 9e-60 201.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KFH46762.1 - 3.3e-17 62.9 0.4 6e-17 62.1 0.3 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain HAS-barrel PF09378.5 KFH46762.1 - 0.0021 17.9 0.6 0.0043 16.9 0.4 1.5 1 0 0 1 1 1 1 HAS barrel domain DASH_Dad3 PF08656.5 KFH46763.1 - 3.3e-28 97.1 0.0 3.7e-28 97.0 0.0 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad3 CK2S PF15011.1 KFH46763.1 - 0.061 13.1 0.1 0.073 12.8 0.0 1.1 1 0 0 1 1 1 0 Casein Kinase 2 substrate Peptidase_M75 PF09375.5 KFH46763.1 - 0.094 12.0 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Imelysin YopE PF03545.8 KFH46763.1 - 0.097 12.6 0.0 0.15 11.9 0.0 1.4 1 1 0 1 1 1 0 Yersinia virulence determinant (YopE) EF-hand_6 PF13405.1 KFH46764.1 - 8e-07 28.4 1.1 0.0072 16.1 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 KFH46764.1 - 5e-06 25.6 0.2 0.00036 19.7 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 KFH46764.1 - 0.00024 21.1 0.9 0.00024 21.1 0.6 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 KFH46764.1 - 0.00045 19.7 0.5 0.0017 17.8 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KFH46764.1 - 0.001 18.2 0.2 0.036 13.3 0.0 2.4 2 0 0 2 2 2 1 EF hand adh_short PF00106.20 KFH46766.1 - 8.3e-30 103.8 2.8 1.2e-29 103.4 1.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH46766.1 - 2.5e-27 96.2 0.1 3.1e-27 95.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH46766.1 - 2.6e-09 36.9 2.6 8.3e-09 35.3 1.8 1.7 1 1 0 1 1 1 1 KR domain Pro_isomerase PF00160.16 KFH46768.1 - 1.5e-42 145.3 0.0 3.1e-42 144.4 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RasGEF PF00617.14 KFH46769.1 - 1.3e-46 158.7 0.1 2.1e-46 158.0 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KFH46769.1 - 1.5e-14 53.9 0.0 6e-14 52.0 0.0 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif HMGL-like PF00682.14 KFH46771.1 - 1.7e-39 135.8 0.3 2.4e-38 132.1 0.2 2.0 1 1 0 1 1 1 1 HMGL-like ketoacyl-synt PF00109.21 KFH46772.1 - 0.0072 15.8 1.1 0.09 12.2 0.0 2.5 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain PPR_1 PF12854.2 KFH46772.1 - 0.063 12.7 1.5 0.74 9.3 0.1 3.0 1 1 1 2 2 2 0 PPR repeat RRN3 PF05327.6 KFH46772.1 - 0.15 10.1 0.0 0.22 9.6 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Metallophos PF00149.23 KFH46773.1 - 2.3e-37 128.3 0.1 1.8e-32 112.4 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase adh_short PF00106.20 KFH46774.1 - 2.1e-30 105.8 0.6 4e-30 104.9 0.4 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH46774.1 - 8.1e-12 45.1 3.5 7.5e-11 42.0 2.4 2.4 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFH46774.1 - 6.8e-09 35.8 0.0 9.8e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KFH46774.1 - 0.0054 16.7 0.1 0.014 15.3 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding DFP PF04127.10 KFH46774.1 - 0.017 14.7 0.1 0.069 12.7 0.1 1.9 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Epimerase PF01370.16 KFH46774.1 - 0.03 13.7 0.1 0.067 12.6 0.1 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GHMP_kinases_N PF00288.21 KFH46774.1 - 0.032 14.2 0.0 0.077 13.0 0.0 1.7 1 0 0 1 1 1 0 GHMP kinases N terminal domain DUF1776 PF08643.5 KFH46774.1 - 0.041 13.0 0.0 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) 3Beta_HSD PF01073.14 KFH46774.1 - 0.12 11.0 0.1 0.17 10.5 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RNase_HII PF01351.13 KFH46775.1 - 5.2e-45 153.5 0.0 7.2e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII Peptidase_M41 PF01434.13 KFH46777.1 - 6.9e-63 211.9 0.6 1.1e-62 211.3 0.4 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KFH46777.1 - 1.5e-43 148.1 0.0 3.2e-43 147.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFH46777.1 - 1e-06 28.5 0.1 4.5e-06 26.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KFH46777.1 - 1.7e-05 25.6 0.0 4.5e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KFH46777.1 - 4.1e-05 22.7 0.0 0.0001 21.4 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KFH46777.1 - 5e-05 23.1 0.0 0.00027 20.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 KFH46777.1 - 7.4e-05 21.6 0.0 0.00013 20.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 KFH46777.1 - 8.8e-05 22.5 2.3 0.0018 18.3 1.6 2.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFH46777.1 - 0.00049 20.2 0.3 0.013 15.6 0.2 2.6 1 1 0 1 1 1 1 AAA domain Bac_DnaA PF00308.13 KFH46777.1 - 0.00077 19.1 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial dnaA protein AAA_19 PF13245.1 KFH46777.1 - 0.00095 18.8 0.3 0.0029 17.3 0.2 1.8 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KFH46777.1 - 0.0015 17.9 0.4 0.0051 16.2 0.1 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.1 KFH46777.1 - 0.0052 16.2 1.2 0.18 11.2 0.2 2.6 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KFH46777.1 - 0.0061 15.6 1.2 0.019 14.0 0.2 2.0 1 1 1 2 2 2 1 Zeta toxin AAA_14 PF13173.1 KFH46777.1 - 0.0078 16.1 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KFH46777.1 - 0.012 14.8 0.1 0.03 13.4 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 KFH46777.1 - 0.019 14.9 0.0 0.046 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 KFH46777.1 - 0.039 13.8 0.0 0.21 11.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.1 KFH46777.1 - 0.048 13.6 0.0 0.18 11.8 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.1 KFH46777.1 - 0.077 13.2 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KFH46777.1 - 0.079 12.6 1.9 0.97 9.0 0.1 2.7 3 0 0 3 3 3 0 NACHT domain PhoH PF02562.11 KFH46777.1 - 0.088 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Calcipressin PF04847.7 KFH46779.1 - 1.8e-46 158.0 0.1 2.3e-46 157.6 0.1 1.1 1 0 0 1 1 1 1 Calcipressin Phage_cap_P2 PF05125.7 KFH46779.1 - 0.018 13.9 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 Phage major capsid protein, P2 family DUF866 PF05907.8 KFH46781.1 - 3.3e-50 169.7 0.3 3.7e-50 169.5 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) DUF3716 PF12511.3 KFH46781.1 - 0.036 13.6 2.5 0.072 12.7 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) Cytochrome_C7 PF14522.1 KFH46781.1 - 0.053 13.1 0.3 0.079 12.6 0.2 1.3 1 0 0 1 1 1 0 Cytochrome c7 Cas_CXXC_CXXC PF09706.5 KFH46781.1 - 0.36 11.0 2.7 0.45 10.7 1.1 1.8 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) Zn_Tnp_IS1595 PF12760.2 KFH46781.1 - 4.4 7.1 6.2 31 4.4 4.3 2.2 1 1 0 1 1 1 0 Transposase zinc-ribbon domain RNA_pol_Rpc82 PF05645.8 KFH46782.1 - 7.9e-48 163.2 0.6 4.4e-47 160.8 0.0 2.5 4 0 0 4 4 4 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 KFH46782.1 - 1.5e-16 60.0 2.3 3.3e-13 49.2 0.1 4.0 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 KFH46782.1 - 5.4e-06 25.8 1.2 0.026 14.0 0.0 3.0 3 1 0 3 3 3 2 TFIIE alpha subunit Collagen PF01391.13 KFH46782.1 - 0.078 12.5 3.7 0.18 11.3 2.6 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) HSF_DNA-bind PF00447.12 KFH46783.1 - 1.3e-28 99.2 0.2 3.5e-28 97.7 0.1 1.8 1 0 0 1 1 1 1 HSF-type DNA-binding DUF904 PF06005.7 KFH46783.1 - 0.53 10.6 16.2 2.4 8.5 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF904) Aldedh PF00171.17 KFH46784.1 - 3.2e-187 622.4 0.1 3.6e-187 622.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KFH46784.1 - 0.11 11.7 0.0 4.9 6.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Glyco_hydro_72 PF03198.9 KFH46785.1 - 3.6e-88 295.5 0.4 7.9e-88 294.4 0.3 1.5 1 1 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 KFH46785.1 - 0.021 14.0 0.3 0.24 10.5 0.2 2.2 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 KFH46785.1 - 0.051 12.4 0.0 0.09 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Pga1 PF10333.4 KFH46786.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 GPI-Mannosyltransferase II co-activator Pep_deformylase PF01327.16 KFH46787.1 - 0.14 11.5 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Polypeptide deformylase PSP1 PF04468.7 KFH46788.1 - 9.9e-31 105.5 0.7 1.7e-30 104.8 0.5 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region LsmAD PF06741.8 KFH46789.1 - 3.7e-20 71.7 3.1 3.7e-20 71.7 2.1 2.3 2 0 0 2 2 2 1 LsmAD domain LRR_4 PF12799.2 KFH46790.1 - 0.0085 15.6 2.0 0.34 10.5 0.1 3.8 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) SHMT PF00464.14 KFH46791.1 - 6.8e-198 656.9 0.0 7.9e-198 656.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 KFH46791.1 - 0.00041 19.6 0.0 0.00054 19.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KFH46791.1 - 0.037 12.7 0.0 0.055 12.1 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Histone PF00125.19 KFH46792.1 - 1.5e-31 108.3 0.4 1.7e-31 108.1 0.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KFH46792.1 - 1.6e-06 28.2 0.0 2e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KFH46792.1 - 0.0018 18.2 0.0 0.0024 17.8 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KFH46792.1 - 0.0062 16.2 0.0 0.009 15.7 0.0 1.3 1 1 0 1 1 1 1 Bromodomain associated DUF3554 PF12074.3 KFH46793.1 - 1.5e-71 241.6 0.2 2.5e-69 234.3 0.0 4.2 4 0 0 4 4 4 1 Domain of unknown function (DUF3554) HEAT PF02985.17 KFH46793.1 - 1e-44 146.5 23.3 0.0064 16.4 0.0 22.1 24 0 0 24 24 22 9 HEAT repeat HEAT_2 PF13646.1 KFH46793.1 - 2.8e-43 146.1 52.4 4.1e-10 39.8 0.1 17.3 11 3 5 16 16 16 11 HEAT repeats HEAT_EZ PF13513.1 KFH46793.1 - 1.9e-38 129.9 54.7 6.1e-07 29.7 0.1 23.0 17 3 7 24 24 23 9 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KFH46793.1 - 5.6e-15 55.5 0.0 0.039 14.3 0.0 10.3 9 3 2 11 11 9 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 KFH46793.1 - 4.4e-14 52.4 0.0 0.0063 15.8 0.0 6.9 7 1 1 9 9 9 4 CLASP N terminal ParcG PF10274.4 KFH46793.1 - 8.4e-13 48.6 1.4 0.00013 21.9 0.0 6.9 7 1 1 8 8 8 3 Parkin co-regulated protein Cnd1 PF12717.2 KFH46793.1 - 2.1e-12 47.2 0.1 0.34 10.7 0.0 9.3 6 2 3 9 9 9 2 non-SMC mitotic condensation complex subunit 1 UME PF08064.8 KFH46793.1 - 3.8e-08 33.2 0.0 2.5 8.0 0.0 7.4 6 1 0 7 7 6 1 UME (NUC010) domain Adaptin_N PF01602.15 KFH46793.1 - 2.2e-07 29.6 13.4 0.027 12.8 0.2 8.3 7 3 2 9 9 9 2 Adaptin N terminal region Ipi1_N PF12333.3 KFH46793.1 - 7.2e-06 25.9 4.5 0.024 14.6 0.0 6.5 8 0 0 8 8 7 1 Rix1 complex component involved in 60S ribosome maturation MMS19_C PF12460.3 KFH46793.1 - 0.00024 19.9 7.3 5.6 5.5 0.1 7.1 8 0 0 8 8 8 1 RNAPII transcription regulator C-terminal TFCD_C PF12612.3 KFH46793.1 - 0.00037 19.9 0.7 0.12 11.7 0.1 5.5 5 1 0 5 5 5 1 Tubulin folding cofactor D C terminal DUF3535 PF12054.3 KFH46793.1 - 0.0015 17.2 0.3 0.027 13.1 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) Mo25 PF08569.6 KFH46793.1 - 0.0096 14.9 0.1 42 3.0 0.0 4.8 4 1 1 5 5 5 0 Mo25-like HBS1_N PF08938.5 KFH46793.1 - 0.15 12.2 4.6 0.19 11.8 0.0 3.4 3 0 0 3 3 3 0 HBS1 N-terminus FtsJ PF01728.14 KFH46794.1 - 1.5e-47 161.9 0.0 1.9e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Mito_fiss_reg PF05308.6 KFH46794.1 - 0.28 10.5 3.0 0.42 9.9 2.1 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Fungal_trans PF04082.13 KFH46795.1 - 1.8e-24 85.9 0.0 2.9e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH46795.1 - 5.6e-06 26.1 15.4 9.6e-06 25.4 10.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clusterin PF01093.12 KFH46795.1 - 0.6 8.8 2.0 0.99 8.1 1.4 1.2 1 0 0 1 1 1 0 Clusterin RNA_pol_Rpb1_5 PF04998.12 KFH46796.1 - 8.6e-89 297.4 0.0 1.5e-88 296.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KFH46796.1 - 4e-64 215.5 0.3 9.8e-64 214.2 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KFH46796.1 - 4.5e-35 120.6 0.0 1.2e-34 119.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 KFH46796.1 - 1.5e-32 113.2 1.6 3.1e-27 95.7 0.6 3.0 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 KFH46796.1 - 3.4e-18 65.3 0.0 1.4e-17 63.4 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Glyco_hydro_6 PF01341.12 KFH46797.1 - 2.1e-94 316.3 0.2 2.6e-94 316.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Catalase-rel PF06628.7 KFH46798.1 - 0.064 13.1 0.0 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 Catalase-related immune-responsive DUF964 PF06133.6 KFH46798.1 - 0.89 9.5 3.9 0.98 9.4 0.8 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF964) Catalase PF00199.14 KFH46799.1 - 2.1e-161 536.9 0.6 2.7e-161 536.5 0.4 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KFH46799.1 - 6.9e-16 57.8 0.0 1.3e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 KFH46799.1 - 2.4e-12 46.5 0.0 4.3e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family zf-C2H2 PF00096.21 KFH46800.1 - 4.6e-14 51.8 21.2 3.2e-05 24.0 1.6 4.0 3 1 1 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFH46800.1 - 1.5e-11 43.7 15.1 0.00046 20.3 0.2 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFH46800.1 - 2.8e-05 24.1 24.0 0.00033 20.7 1.2 4.4 4 1 0 4 4 4 3 Zinc-finger double domain zf-C2HC_2 PF13913.1 KFH46800.1 - 0.022 14.4 0.5 0.061 13.0 0.3 1.8 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 KFH46800.1 - 0.085 13.0 11.7 0.23 11.6 0.1 3.3 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding PyrI_C PF02748.10 KFH46800.1 - 0.12 11.8 0.8 0.28 10.6 0.5 1.6 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_6 PF13912.1 KFH46800.1 - 0.13 12.1 2.1 0.43 10.5 1.4 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KFH46800.1 - 0.37 11.1 11.0 1.5 9.2 0.6 3.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-BED PF02892.10 KFH46800.1 - 0.66 9.7 10.9 0.52 10.1 2.9 2.9 2 1 1 3 3 3 0 BED zinc finger zf-TRAF PF02176.13 KFH46800.1 - 0.69 10.3 12.2 2 8.8 5.3 2.9 1 1 2 3 3 3 0 TRAF-type zinc finger zf-C2H2_2 PF12756.2 KFH46800.1 - 0.95 9.6 8.3 1.5 8.9 2.3 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) NAD_binding_6 PF08030.7 KFH46801.1 - 3.1e-17 62.9 0.0 4.8e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KFH46801.1 - 6.3e-13 48.8 12.6 6.3e-13 48.8 8.7 1.7 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KFH46801.1 - 1.7e-09 37.5 0.0 3.4e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 KFH46801.1 - 0.058 13.9 0.0 14 6.3 0.0 2.5 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Wzy_C PF04932.10 KFH46801.1 - 0.082 12.6 2.3 2.9 7.6 0.1 2.6 2 0 0 2 2 2 0 O-Antigen ligase TAF8_C PF10406.4 KFH46802.1 - 8.1e-15 54.6 0.1 1.5e-14 53.7 0.1 1.5 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 KFH46802.1 - 2.2e-06 27.2 0.0 2.5e-05 23.9 0.0 2.5 3 0 0 3 3 3 1 Bromodomain associated Glyoxalase_2 PF12681.2 KFH46803.1 - 5.7e-11 42.9 0.0 7.9e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KFH46803.1 - 0.0089 15.9 0.0 0.011 15.6 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NmrA PF05368.8 KFH46805.1 - 5.4e-13 48.7 0.1 1.7e-09 37.3 0.1 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFH46805.1 - 0.0031 17.5 0.0 0.0051 16.8 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KFH46805.1 - 0.0045 15.7 0.0 0.0067 15.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KFH46805.1 - 0.0053 16.4 0.0 0.0092 15.6 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KFH46805.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Epimerase PF01370.16 KFH46805.1 - 0.016 14.6 0.0 0.31 10.4 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KFH46805.1 - 0.065 12.1 0.0 0.097 11.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein p450 PF00067.17 KFH46806.1 - 1.6e-11 43.4 0.1 4.7e-09 35.2 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 PMP1_2 PF08114.6 KFH46807.1 - 0.00028 20.2 1.1 0.00039 19.8 0.8 1.3 1 0 0 1 1 1 1 ATPase proteolipid family DUF3149 PF11346.3 KFH46807.1 - 0.029 13.9 0.5 0.041 13.4 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Na_H_Exchanger PF00999.16 KFH46807.1 - 0.035 12.6 0.4 0.03 12.8 0.3 1.0 1 0 0 1 1 1 0 Sodium/hydrogen exchanger family Sensor PF13796.1 KFH46807.1 - 0.048 13.2 0.3 0.05 13.2 0.2 1.1 1 0 0 1 1 1 0 Putative sensor Rifin_STEVOR PF02009.11 KFH46807.1 - 0.057 13.0 0.5 0.052 13.1 0.4 1.0 1 0 0 1 1 1 0 Rifin/stevor family AMA-1 PF02430.10 KFH46807.1 - 0.15 10.9 0.2 0.14 11.0 0.1 1.0 1 0 0 1 1 1 0 Apical membrane antigen 1 DHO_dh PF01180.16 KFH46808.1 - 1.3e-20 73.5 0.0 3.6e-20 72.1 0.0 1.6 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase Fork_head PF00250.13 KFH46809.1 - 2.1e-10 40.4 0.0 5.1e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 KFH46809.1 - 0.00031 20.7 0.1 0.00068 19.7 0.1 1.5 1 0 0 1 1 1 1 FHA domain Glycos_transf_1 PF00534.15 KFH46810.1 - 1.2e-16 60.6 0.0 2.9e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.3 KFH46810.1 - 7.2e-07 29.0 0.0 1.8e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3492) Glyco_trans_1_4 PF13692.1 KFH46810.1 - 7.1e-05 22.9 0.0 0.00017 21.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 FUSC-like PF12805.2 KFH46810.1 - 0.93 8.3 4.5 1.7 7.4 3.1 1.4 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS ER-remodelling PF14755.1 KFH46812.1 - 0.092 12.8 3.3 0.44 10.5 2.6 1.8 2 0 0 2 2 2 0 Intracellular membrane remodeller zf-C2H2 PF00096.21 KFH46813.1 - 1.3e-09 37.8 12.1 0.014 15.6 0.9 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFH46813.1 - 2.8e-06 27.2 15.0 0.0031 17.7 1.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.7 KFH46813.1 - 7.8 6.7 6.6 6.6 6.9 0.9 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding MFS_1 PF07690.11 KFH46814.1 - 1.9e-37 128.8 44.8 1.9e-37 128.8 31.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH46814.1 - 9.5e-11 40.9 11.5 9.5e-11 40.9 8.0 3.3 3 0 0 3 3 3 2 Sugar (and other) transporter Ribosomal_L18p PF00861.17 KFH46815.1 - 1.3e-40 138.2 0.1 1.3e-40 138.2 0.1 1.6 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 KFH46815.1 - 1.6e-32 111.9 10.2 1.6e-32 111.9 7.1 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region UvrD-helicase PF00580.16 KFH46815.1 - 0.0055 16.0 5.0 0.0055 16.0 3.4 1.7 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain CBM_48 PF02922.13 KFH46816.1 - 0.013 15.5 0.9 0.044 13.8 0.1 2.2 2 0 0 2 2 2 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Mitochondr_Som1 PF11093.3 KFH46817.1 - 3.1e-06 26.8 0.1 3.4e-06 26.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial export protein Som1 MBOAT PF03062.14 KFH46818.1 - 1.7e-27 96.4 19.5 1.9e-27 96.2 10.9 2.6 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 KFH46818.1 - 0.00092 19.2 0.4 0.003 17.6 0.3 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF4064 PF13273.1 KFH46818.1 - 3.9 7.6 6.9 21 5.2 0.6 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) DHquinase_I PF01487.10 KFH46819.1 - 4.6e-53 180.1 0.0 8.1e-53 179.3 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase Avian_gp85 PF03708.9 KFH46819.1 - 0.079 12.1 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Avian retrovirus envelope protein, gp85 DSBA PF01323.15 KFH46820.1 - 6.5e-25 87.8 0.0 7.5e-25 87.6 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Podoplanin PF05808.6 KFH46821.1 - 6.5e-06 25.8 10.9 1.2e-05 24.9 7.5 1.3 1 0 0 1 1 1 1 Podoplanin CFEM PF05730.6 KFH46821.1 - 1e-05 25.2 5.7 2e-05 24.3 4.0 1.5 1 0 0 1 1 1 1 CFEM domain SKG6 PF08693.5 KFH46821.1 - 2.9e-05 23.2 5.8 8.4e-05 21.8 4.0 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rifin_STEVOR PF02009.11 KFH46821.1 - 0.0024 17.5 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 Rifin/stevor family Rax2 PF12768.2 KFH46821.1 - 0.005 16.0 0.2 0.0077 15.4 0.1 1.3 1 1 0 1 1 1 1 Cortical protein marker for cell polarity DUF4448 PF14610.1 KFH46821.1 - 0.011 15.1 0.0 0.017 14.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) IncA PF04156.9 KFH46821.1 - 0.025 14.1 0.3 0.047 13.2 0.2 1.3 1 0 0 1 1 1 0 IncA protein TMEM154 PF15102.1 KFH46821.1 - 0.097 12.3 8.9 2.4 7.8 6.2 2.2 1 1 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.1 KFH46821.1 - 0.12 12.8 0.1 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF347 PF03988.7 KFH46821.1 - 0.14 12.0 1.1 0.29 11.0 0.8 1.5 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Presenilin PF01080.12 KFH46821.1 - 0.89 8.3 2.5 1.4 7.7 1.7 1.3 1 0 0 1 1 1 0 Presenilin Hamartin PF04388.7 KFH46821.1 - 0.93 8.0 3.7 0.95 8.0 2.6 1.1 1 0 0 1 1 1 0 Hamartin protein Mito_carr PF00153.22 KFH46822.1 - 2.2e-75 248.4 1.9 5.6e-25 86.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MR_MLE_C PF13378.1 KFH46823.1 - 1.6e-20 73.0 0.0 4e-20 71.8 0.0 1.7 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KFH46823.1 - 1.9e-13 50.7 0.0 6.8e-13 48.9 0.0 2.0 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 KFH46823.1 - 2.3e-09 37.2 0.0 3.8e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Glyco_hydro_42 PF02449.10 KFH46823.1 - 0.037 13.1 0.0 0.25 10.4 0.0 1.9 2 0 0 2 2 2 0 Beta-galactosidase RTA1 PF04479.8 KFH46824.1 - 3.6e-17 62.6 5.7 5.2e-17 62.0 3.9 1.2 1 0 0 1 1 1 1 RTA1 like protein NUDIX_4 PF14815.1 KFH46825.1 - 0.2 11.0 1.6 0.49 9.8 0.3 2.2 2 0 0 2 2 2 0 NUDIX domain Hydrolase_6 PF13344.1 KFH46826.1 - 3e-22 78.4 0.0 5.7e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFH46826.1 - 2.6e-12 46.2 0.1 1.9e-11 43.4 0.0 2.5 3 0 0 3 3 3 1 HAD-hyrolase-like HAD_2 PF13419.1 KFH46826.1 - 0.021 15.0 0.0 2.8 8.1 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFH46826.1 - 0.061 13.7 0.0 1.1 9.5 0.0 2.2 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase PS_Dcarbxylase PF02666.10 KFH46827.1 - 3.9e-53 179.7 0.0 1.5e-52 177.8 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylserine decarboxylase C2 PF00168.25 KFH46827.1 - 6.9e-35 118.7 0.3 3.8e-18 65.0 0.0 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_1 PF00036.27 KFH46827.1 - 0.005 16.0 0.1 0.019 14.2 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 KFH46827.1 - 0.014 14.7 0.0 0.054 12.8 0.0 2.1 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.1 KFH46827.1 - 0.016 15.0 0.5 0.086 12.7 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.1 KFH46827.1 - 0.018 15.1 2.0 0.031 14.4 0.1 2.3 2 0 0 2 2 2 0 EF-hand domain pair HA2 PF04408.18 KFH46828.1 - 4.4e-18 65.1 0.0 1e-17 64.0 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KFH46828.1 - 5.2e-12 45.4 0.1 1.4e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFH46828.1 - 3.5e-11 42.9 0.0 8.1e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KFH46828.1 - 1.3e-08 35.0 1.2 2.4e-08 34.1 0.1 2.1 2 0 0 2 2 2 1 AAA domain OB_NTP_bind PF07717.11 KFH46828.1 - 1.2e-06 28.3 0.0 2.9e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold KaiC PF06745.8 KFH46828.1 - 0.0088 15.1 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 KaiC NB-ARC PF00931.17 KFH46828.1 - 0.012 14.5 0.0 0.022 13.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 KFH46828.1 - 0.019 15.2 0.0 0.054 13.7 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 KFH46828.1 - 0.021 14.3 0.0 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 KFH46828.1 - 0.028 14.1 0.1 0.082 12.6 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase NACHT PF05729.7 KFH46828.1 - 0.05 13.2 0.0 0.26 10.9 0.0 2.3 2 0 0 2 2 2 0 NACHT domain zf-RING_2 PF13639.1 KFH46829.1 - 0.0017 18.1 2.3 0.0032 17.2 1.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFH46829.1 - 2.7 8.0 6.0 0.55 10.3 1.5 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Histone PF00125.19 KFH46831.1 - 1.6e-15 56.9 0.1 1.9e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 KFH46831.1 - 0.0001 22.1 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 KFH46831.1 - 0.00011 22.3 0.1 0.00016 21.8 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KFH46831.1 - 0.00014 21.7 0.2 0.00031 20.7 0.0 1.7 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KFH46831.1 - 0.017 14.8 0.0 0.021 14.5 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KFH46831.1 - 0.021 14.0 0.0 0.022 14.0 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T 2OG-FeII_Oxy_2 PF13532.1 KFH46832.1 - 1.8e-26 93.1 0.0 2.8e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.15 KFH46832.1 - 7.4e-22 78.1 0.1 7.6e-21 74.8 0.0 2.2 1 1 0 1 1 1 1 Isochorismatase family GST_C_3 PF14497.1 KFH46832.1 - 1.9e-07 31.4 0.0 6.7e-07 29.7 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFH46832.1 - 0.0002 21.2 0.0 0.00045 20.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFH46832.1 - 0.0037 17.2 0.0 0.0088 16.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pectate_lyase PF03211.8 KFH46833.1 - 5e-68 228.7 1.6 6.5e-68 228.3 1.1 1.0 1 0 0 1 1 1 1 Pectate lyase Ribosomal_L19e PF01280.15 KFH46834.1 - 4.5e-60 201.7 9.7 4.5e-60 201.7 6.7 1.8 2 0 0 2 2 2 1 Ribosomal protein L19e RNase_H2-Ydr279 PF09468.5 KFH46834.1 - 0.015 14.5 0.9 0.016 14.4 0.6 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) TLE_N PF03920.10 KFH46835.1 - 0.03 14.1 6.7 1.5 8.6 0.5 2.9 2 2 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain DUF4407 PF14362.1 KFH46835.1 - 0.27 10.1 28.1 0.049 12.5 3.7 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) Reo_sigmaC PF04582.7 KFH46835.1 - 0.42 9.7 5.0 2.6 7.1 0.9 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Spectrin PF00435.16 KFH46835.1 - 0.76 10.0 22.9 1.5 9.1 3.3 3.2 1 1 2 3 3 3 0 Spectrin repeat MFS_1 PF07690.11 KFH46836.1 - 1.8e-08 33.5 25.0 1.8e-08 33.5 17.3 5.0 3 2 2 5 5 5 3 Major Facilitator Superfamily PRP3 PF08572.5 KFH46837.1 - 2.4e-69 233.1 0.5 3.6e-69 232.5 0.4 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 KFH46837.1 - 4.4e-38 129.8 0.4 4.4e-38 129.8 0.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) OST3_OST6 PF04756.8 KFH46838.1 - 3.7e-22 78.6 0.4 5.3e-22 78.1 0.3 1.2 1 0 0 1 1 1 1 OST3 / OST6 family DUF2561 PF10812.3 KFH46838.1 - 0.0011 18.6 0.5 0.12 11.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2561) PhageMin_Tail PF10145.4 KFH46838.1 - 0.0083 15.7 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Phage-related minor tail protein Abi PF02517.11 KFH46838.1 - 0.053 13.6 1.5 0.11 12.6 0.6 1.8 1 1 0 1 1 1 0 CAAX protease self-immunity RNA_pol_Rpb1_5 PF04998.12 KFH46839.1 - 2.3e-86 289.4 0.1 4e-86 288.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 KFH46839.1 - 1.3e-79 267.9 0.0 1.7e-79 267.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 KFH46839.1 - 3.5e-64 215.7 0.0 6.3e-64 214.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KFH46839.1 - 1.4e-38 132.1 0.0 2.8e-38 131.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 KFH46839.1 - 8e-31 105.9 0.1 2e-30 104.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Auto_anti-p27 PF06677.7 KFH46839.1 - 0.6 9.9 3.7 1.9 8.2 0.0 3.0 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) COX5B PF01215.14 KFH46840.1 - 0.035 13.7 0.0 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb WD40 PF00400.27 KFH46842.1 - 2.1e-62 204.9 22.5 1.2e-11 43.9 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KFH46842.1 - 7e-06 24.4 6.7 0.3 9.1 1.8 4.0 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KFH46842.1 - 0.024 12.9 0.0 3.4 5.8 0.1 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain Mpp10 PF04006.7 KFH46843.1 - 9.4e-91 305.0 63.7 4.3e-83 279.6 8.7 2.1 1 1 1 2 2 2 2 Mpp10 protein Spherulin4 PF12138.3 KFH46844.1 - 2.9e-60 203.8 0.0 3.6e-60 203.5 0.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Abhydrolase_6 PF12697.2 KFH46845.1 - 1.9e-08 34.5 2.5 3.1e-08 33.7 1.7 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KFH46845.1 - 5e-08 32.8 0.0 7.4e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 KFH46845.1 - 9.1e-06 25.1 0.0 1.6e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 KFH46845.1 - 3.7e-05 23.5 0.3 7.9e-05 22.4 0.1 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family LCAT PF02450.10 KFH46845.1 - 0.00027 20.0 0.0 0.00033 19.7 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.15 KFH46845.1 - 0.0021 17.6 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_9 PF10081.4 KFH46845.1 - 0.0061 15.3 0.2 0.88 8.2 0.1 2.1 1 1 1 2 2 2 2 Alpha/beta-hydrolase family Lipase_2 PF01674.13 KFH46845.1 - 0.05 12.9 0.0 0.096 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) DUF900 PF05990.7 KFH46845.1 - 0.07 12.4 0.0 0.099 11.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF915 PF06028.6 KFH46845.1 - 0.13 11.3 0.0 0.27 10.2 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Sulfate_transp PF00916.15 KFH46846.1 - 5.3e-06 25.6 1.0 5.3e-06 25.6 0.7 2.7 2 1 0 2 2 2 2 Sulfate transporter family Glyco_hydro_114 PF03537.8 KFH46847.1 - 1.9e-22 78.8 0.1 3.5e-22 77.9 0.1 1.4 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 EPSP_synthase PF00275.15 KFH46849.1 - 1.8e-126 422.0 0.0 6.2e-126 420.2 0.0 1.8 2 0 0 2 2 2 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 KFH46849.1 - 1.1e-101 339.1 0.0 2.1e-101 338.2 0.0 1.5 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 KFH46849.1 - 4.8e-62 209.5 0.0 7.5e-62 208.8 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 KFH46849.1 - 1.9e-37 128.5 0.0 8.6e-36 123.1 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 KFH46849.1 - 2.5e-23 81.9 0.0 1.3e-22 79.6 0.0 2.2 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.1 KFH46849.1 - 3.6e-09 36.3 0.0 8.8e-09 35.0 0.0 1.6 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.15 KFH46849.1 - 9e-09 35.5 0.0 2.2e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_33 PF13671.1 KFH46849.1 - 1e-05 25.4 0.0 0.0014 18.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KFH46849.1 - 1.1e-05 26.2 0.0 3.4e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KFH46849.1 - 0.012 15.4 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KFH46849.1 - 0.1 12.7 0.0 0.33 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KFH46849.1 - 0.12 12.7 0.0 0.4 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KFH46849.1 - 0.13 11.3 0.0 0.28 10.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Epimerase PF01370.16 KFH46850.1 - 4e-36 124.6 0.0 2.1e-34 118.9 0.0 2.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 KFH46850.1 - 4.9e-16 58.4 0.1 1.2e-15 57.1 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 KFH46850.1 - 2e-06 26.6 0.8 0.0082 14.8 0.0 2.7 3 1 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KFH46850.1 - 2.7e-06 26.4 0.2 6.2e-06 25.3 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 KFH46850.1 - 0.00063 18.7 0.0 0.0035 16.2 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KFH46850.1 - 0.0017 18.3 0.1 0.023 14.5 0.0 2.7 2 1 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KFH46850.1 - 0.0026 17.7 0.4 0.59 10.1 0.0 2.8 3 0 0 3 3 3 1 NADH(P)-binding KR PF08659.5 KFH46850.1 - 0.0077 15.9 0.1 0.082 12.5 0.0 2.3 1 1 0 1 1 1 1 KR domain DAO PF01266.19 KFH46850.1 - 0.015 14.1 0.1 0.045 12.6 0.1 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 KFH46850.1 - 0.047 13.0 0.0 0.097 12.0 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RmlD_sub_bind PF04321.12 KFH46850.1 - 0.078 11.8 0.0 0.28 10.0 0.0 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain zf-MIZ PF02891.15 KFH46851.1 - 5.5e-12 45.0 0.1 1.3e-11 43.8 0.1 1.7 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-C3HC4_2 PF13923.1 KFH46852.1 - 6.1e-09 35.7 7.0 1.1e-08 34.9 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFH46852.1 - 8.2e-08 31.9 5.3 1.4e-07 31.2 3.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KFH46852.1 - 1.8e-07 30.7 2.8 5.8e-07 29.0 2.1 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFH46852.1 - 9.4e-07 28.4 4.5 1.7e-06 27.6 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFH46852.1 - 5.2e-06 26.0 3.7 9.3e-06 25.2 2.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFH46852.1 - 8.6e-06 25.5 6.1 8e-05 22.4 4.3 2.2 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFH46852.1 - 0.0017 18.0 1.4 0.0017 18.0 0.9 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-MIZ PF02891.15 KFH46852.1 - 0.16 11.5 6.9 0.14 11.6 3.5 2.0 2 1 0 2 2 2 0 MIZ/SP-RING zinc finger Prp19_bind PF06991.6 KFH46852.1 - 0.29 10.3 4.4 0.31 10.2 2.2 1.7 2 0 0 2 2 2 0 Splicing factor, Prp19-binding domain TerY-C PF15616.1 KFH46852.1 - 0.63 9.9 3.3 2.5 8.0 2.3 1.9 1 1 0 1 1 1 0 TerY-C metal binding domain HAD_2 PF13419.1 KFH46853.1 - 1.4e-15 57.9 0.0 4e-15 56.4 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFH46853.1 - 0.025 14.2 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like CH PF00307.26 KFH46854.1 - 3e-60 200.9 0.0 1.4e-16 60.5 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 KFH46854.1 - 2.1e-05 24.5 0.4 0.00028 20.9 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair CAMSAP_CH PF11971.3 KFH46854.1 - 0.0027 17.3 0.0 6 6.5 0.0 3.7 4 0 0 4 4 4 1 CAMSAP CH domain EF-hand_1 PF00036.27 KFH46854.1 - 0.032 13.5 1.0 4.3 6.8 0.1 3.5 3 0 0 3 3 3 0 EF hand EF-hand_6 PF13405.1 KFH46854.1 - 0.74 9.8 3.5 2.8 8.0 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain RRM_1 PF00076.17 KFH46857.1 - 3.2e-05 23.4 0.1 0.0001 21.8 0.1 1.7 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH46857.1 - 7.9e-05 22.4 0.0 0.00012 21.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH46857.1 - 0.019 14.9 0.0 0.084 12.8 0.0 1.9 1 1 1 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L22 PF00237.14 KFH46858.1 - 2.1e-12 46.9 0.1 1.5e-06 28.1 0.0 2.9 3 0 0 3 3 3 2 Ribosomal protein L22p/L17e AMH_N PF04709.7 KFH46859.1 - 0.013 14.4 2.3 0.014 14.4 1.6 1.0 1 0 0 1 1 1 0 Anti-Mullerian hormone, N terminal region DUF915 PF06028.6 KFH46859.1 - 0.047 12.7 0.4 0.051 12.6 0.2 1.0 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) RAB3GAP2_N PF14655.1 KFH46859.1 - 0.33 9.9 3.3 0.36 9.7 2.3 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Med3 PF11593.3 KFH46859.1 - 0.59 9.3 8.5 0.72 9.0 5.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TSA PF03249.8 KFH46859.1 - 9.1 4.6 7.2 9.5 4.6 5.0 1.0 1 0 0 1 1 1 0 Type specific antigen DUF159 PF02586.9 KFH46860.1 - 9e-57 191.9 0.0 1.2e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 Glyco_hydro_19 PF00182.14 KFH46860.1 - 0.1 12.2 0.0 0.94 9.0 0.0 2.1 2 0 0 2 2 2 0 Chitinase class I Fungal_trans PF04082.13 KFH46861.1 - 1.1e-28 99.8 0.6 1.1e-28 99.8 0.4 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH46861.1 - 1.6e-08 34.3 11.1 2.7e-08 33.5 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugarporin_N PF11471.3 KFH46861.1 - 0.44 10.2 3.1 0.34 10.5 0.5 2.0 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension DUF605 PF04652.11 KFH46861.1 - 4.1 6.6 11.2 9.9 5.4 7.8 1.7 1 0 0 1 1 1 0 Vta1 like Arrestin_N PF00339.24 KFH46862.1 - 3.1e-13 49.7 0.0 4.3e-08 33.1 0.0 3.1 3 1 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Fungal_trans PF04082.13 KFH46863.1 - 6.8e-12 44.8 0.8 1.2e-11 43.9 0.5 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain RRM_1 PF00076.17 KFH46864.1 - 5.7e-53 176.4 0.1 4.1e-19 67.9 0.1 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH46864.1 - 7.7e-42 141.1 0.0 1.2e-14 54.0 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH46864.1 - 6.8e-26 89.8 0.0 1.5e-13 50.3 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFH46864.1 - 5e-11 42.1 0.0 0.015 15.0 0.0 3.9 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 KFH46864.1 - 0.00035 20.2 0.0 0.46 10.2 0.0 3.4 2 1 1 3 3 3 1 Nup53/35/40-type RNA recognition motif Lsm_interact PF05391.6 KFH46864.1 - 0.022 14.1 1.1 0.057 12.8 0.7 1.7 1 0 0 1 1 1 0 Lsm interaction motif TarH PF02203.10 KFH46864.1 - 7.4 6.3 9.8 24 4.6 6.8 1.9 1 0 0 1 1 1 0 Tar ligand binding domain homologue DDHD PF02862.12 KFH46865.1 - 2.6e-67 226.9 0.7 1.9e-66 224.1 0.0 2.7 3 1 0 3 3 3 1 DDHD domain adh_short PF00106.20 KFH46866.1 - 5.7e-27 94.6 1.0 7.3e-27 94.3 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH46866.1 - 4.6e-20 72.4 0.0 5.7e-20 72.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH46866.1 - 1.9e-10 40.6 0.4 2.7e-10 40.2 0.3 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 KFH46866.1 - 0.027 13.5 0.1 0.13 11.3 0.0 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_4 PF07993.7 KFH46866.1 - 0.062 12.2 0.0 0.076 11.9 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Epimerase PF01370.16 KFH46866.1 - 0.067 12.6 0.3 0.096 12.1 0.2 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family CTP_transf_2 PF01467.21 KFH46867.1 - 5.3e-24 85.0 0.0 9.2e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase MFS_1 PF07690.11 KFH46868.1 - 4.3e-47 160.5 39.1 4.3e-47 160.5 27.1 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH46868.1 - 8.8e-19 67.4 34.0 1.3e-17 63.5 4.8 3.2 2 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 KFH46868.1 - 2.2e-05 22.9 14.2 2.2e-05 22.9 9.8 2.2 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 KFH46868.1 - 0.0019 16.6 34.7 0.0042 15.5 0.7 3.7 3 1 1 4 4 4 3 MFS/sugar transport protein CHAP PF05257.11 KFH46869.1 - 1.1e-19 70.3 7.4 2.1e-19 69.3 5.2 1.5 1 0 0 1 1 1 1 CHAP domain SH3_3 PF08239.6 KFH46869.1 - 1e-05 25.6 0.4 3.7e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Bacterial SH3 domain Abhydrolase_5 PF12695.2 KFH46870.1 - 1.2e-05 25.0 0.4 1.9e-05 24.4 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KFH46870.1 - 0.1 12.1 0.2 0.22 11.0 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold FAD_binding_3 PF01494.14 KFH46871.1 - 1.9e-31 109.4 0.0 3.6e-31 108.5 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFH46871.1 - 3.2e-09 36.1 0.1 0.00032 19.7 0.0 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KFH46871.1 - 3.9e-05 22.9 0.7 0.2 10.7 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 KFH46871.1 - 6.7e-05 22.1 0.0 0.00012 21.2 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFH46871.1 - 0.00023 21.5 0.1 0.0034 17.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFH46871.1 - 0.00047 20.1 0.1 0.0013 18.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KFH46871.1 - 0.00093 17.9 0.0 0.0015 17.2 0.0 1.5 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 KFH46871.1 - 0.0013 18.6 0.2 0.0038 17.1 0.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFH46871.1 - 0.0016 17.4 0.7 0.16 10.8 0.0 2.4 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KFH46871.1 - 0.0086 16.1 0.4 0.03 14.3 0.2 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFH46871.1 - 0.01 14.3 0.2 0.14 10.5 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 KFH46871.1 - 0.015 14.3 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.16 KFH46871.1 - 0.029 13.9 0.0 0.066 12.7 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 KFH46871.1 - 0.038 12.8 0.5 0.038 12.8 0.4 2.1 2 1 0 3 3 3 0 FAD binding domain NAD_binding_7 PF13241.1 KFH46871.1 - 0.08 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Imm32 PF15579.1 KFH46871.1 - 0.1 12.2 0.4 2.3 7.8 0.2 2.2 2 0 0 2 2 2 0 Immunity protein 32 SE PF08491.5 KFH46871.1 - 0.11 11.3 0.0 0.38 9.5 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase DUF2383 PF09537.5 KFH46871.1 - 0.13 12.5 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) Peptidase_S68 PF10461.4 KFH46871.1 - 2.7 7.7 4.8 0.77 9.5 0.5 2.1 2 0 0 2 2 2 0 Peptidase S68 UQ_con PF00179.21 KFH46872.1 - 4e-33 113.8 0.0 5.2e-33 113.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KFH46872.1 - 0.027 14.3 0.4 0.041 13.7 0.3 1.7 1 1 0 1 1 1 0 RWD domain YL1 PF05764.8 KFH46872.1 - 0.86 9.1 11.8 1.2 8.6 8.2 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Nucleoplasmin PF03066.10 KFH46872.1 - 4 6.9 9.4 5.3 6.5 6.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin CLPTM1 PF05602.7 KFH46873.1 - 4.4e-149 496.9 0.0 5.7e-149 496.5 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) SBP_bac_3 PF00497.15 KFH46874.1 - 5.9e-05 22.4 0.0 0.00023 20.4 0.0 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.6 KFH46874.1 - 0.00018 21.2 0.0 0.00049 19.7 0.0 1.6 1 1 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 KFH46874.1 - 0.091 12.1 0.0 0.19 11.0 0.0 1.5 2 0 0 2 2 2 0 NMT1-like family YfbU PF03887.9 KFH46874.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 2 0 0 2 2 2 0 YfbU domain ADH_zinc_N PF00107.21 KFH46875.1 - 1.1e-09 37.9 0.1 1.7e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFH46875.1 - 0.0001 22.0 0.0 0.00018 21.1 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Phage_lysozyme PF00959.14 KFH46876.1 - 8.1e-17 61.5 0.0 1.1e-16 61.1 0.0 1.2 1 0 0 1 1 1 1 Phage lysozyme Carboxyl_trans PF01039.17 KFH46877.1 - 1.5e-141 472.1 0.0 2.2e-141 471.5 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain Reo_sigmaC PF04582.7 KFH46877.1 - 0.059 12.5 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Reovirus sigma C capsid protein UreF PF01730.11 KFH46879.1 - 1.8e-14 54.0 0.2 3.5e-14 53.1 0.1 1.4 1 0 0 1 1 1 1 UreF DnaJ PF00226.26 KFH46880.1 - 1.1e-26 92.3 3.6 1.8e-26 91.6 2.5 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KFH46880.1 - 2.3e-24 85.0 1.8 5.4e-22 77.4 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain Heme_oxygenase PF01126.15 KFH46881.1 - 6.2e-07 29.1 0.0 4.5e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 Heme oxygenase PAP2_3 PF14378.1 KFH46883.1 - 1.2e-22 80.3 16.3 2.7e-19 69.4 2.4 3.2 2 1 1 3 3 3 2 PAP2 superfamily Fungal_trans_2 PF11951.3 KFH46884.1 - 1.8e-47 161.7 0.3 4.6e-47 160.4 0.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH46884.1 - 1.5e-06 27.9 7.1 3.2e-06 26.9 4.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zip PF02535.17 KFH46884.1 - 0.49 9.3 4.9 1.1 8.1 3.4 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Glyco_hydro_31 PF01055.21 KFH46885.1 - 3.8e-273 905.9 10.6 2.6e-148 494.5 3.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KFH46885.1 - 7.5e-31 105.8 3.3 2.6e-25 88.0 0.2 3.5 3 0 0 3 3 3 2 Galactose mutarotase-like FLILHELTA PF10306.4 KFH46885.1 - 3.2e-30 103.9 0.0 7e-30 102.9 0.0 1.6 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA Glyco_hydro_18 PF00704.23 KFH46885.1 - 4.5e-12 46.0 0.0 1.2e-11 44.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 DUF1279 PF06916.8 KFH46885.1 - 0.045 14.0 0.0 0.093 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) Acyl-CoA_dh_1 PF00441.19 KFH46886.1 - 2e-29 102.6 0.5 4e-29 101.6 0.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFH46886.1 - 9e-16 57.1 0.0 2.1e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KFH46886.1 - 8.3e-14 52.1 0.2 2.7e-13 50.4 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KFH46886.1 - 7.4e-13 48.9 0.3 7.4e-13 48.9 0.2 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HET PF06985.6 KFH46888.1 - 4.9e-32 110.9 0.0 7.7e-32 110.3 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cytochrom_C_2 PF01322.15 KFH46889.1 - 0.12 12.8 0.0 0.28 11.7 0.0 1.6 1 0 0 1 1 1 0 Cytochrome C' DAO PF01266.19 KFH46890.1 - 8.4e-58 195.9 0.4 9.9e-58 195.7 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFH46890.1 - 0.00083 19.3 0.1 0.0019 18.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KFH46890.1 - 0.0034 17.7 0.1 1.9 8.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase LLC1 PF14945.1 KFH46890.1 - 0.016 15.4 0.1 0.035 14.4 0.1 1.4 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein RTA1 PF04479.8 KFH46891.1 - 2.6e-40 138.3 4.7 4.5e-40 137.5 3.2 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF373 PF04123.8 KFH46891.1 - 0.2 10.6 5.2 0.16 10.9 2.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF373) DUF3098 PF11297.3 KFH46891.1 - 2.1 8.1 6.9 2.1 8.1 1.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3098) DUF2721 PF11026.3 KFH46891.1 - 2.2 7.8 17.0 1.9 8.1 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) DUF3671 PF12420.3 KFH46891.1 - 3.5 7.6 6.9 9.4 6.2 3.8 2.3 2 1 0 2 2 2 0 Protein of unknown function TGS PF02824.16 KFH46892.1 - 7.2e-20 70.5 0.1 1.5e-19 69.5 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 KFH46892.1 - 6.5e-19 68.0 0.0 1.4e-18 66.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFH46892.1 - 1.1e-12 47.4 0.0 1.8e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KFH46892.1 - 0.00013 21.8 0.4 0.039 13.7 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 KFH46892.1 - 0.0036 17.7 0.0 0.0094 16.4 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein ArgK PF03308.11 KFH46892.1 - 0.04 12.6 0.1 0.12 11.0 0.1 1.8 2 0 0 2 2 2 0 ArgK protein MCM PF00493.18 KFH46892.1 - 0.11 11.2 0.0 0.19 10.4 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family ATP_bind_1 PF03029.12 KFH46892.1 - 0.33 10.4 1.6 8 5.9 0.1 2.8 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein MARVEL PF01284.18 KFH46894.1 - 8.1e-05 22.4 11.3 0.00012 21.9 7.8 1.2 1 0 0 1 1 1 1 Membrane-associating domain PUL PF08324.6 KFH46895.1 - 2e-37 128.4 0.0 2.9e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.9 KFH46895.1 - 5e-33 114.0 0.0 8.3e-33 113.2 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.15 KFH46895.1 - 3e-15 55.7 0.0 5.9e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KFH46895.1 - 1.9e-06 28.0 0.0 5.8e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.1 KFH46895.1 - 0.00069 19.1 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein AhpC-TSA PF00578.16 KFH46895.1 - 0.00091 18.9 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family DUF2847 PF11009.3 KFH46895.1 - 0.0017 17.9 0.0 0.0029 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2847) Thioredoxin_4 PF13462.1 KFH46895.1 - 0.0033 17.4 0.1 0.01 15.8 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin T4_deiodinase PF00837.12 KFH46895.1 - 0.011 14.7 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Iodothyronine deiodinase RTX PF02382.10 KFH46895.1 - 0.046 11.9 0.2 0.072 11.3 0.2 1.2 1 0 0 1 1 1 0 RTX N-terminal domain Thioredoxin_8 PF13905.1 KFH46895.1 - 0.047 13.8 0.0 0.36 10.9 0.0 2.3 1 1 1 2 2 2 0 Thioredoxin-like Redoxin PF08534.5 KFH46895.1 - 0.099 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Redoxin AAA_3 PF07726.6 KFH46897.1 - 0.028 14.0 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MPC PF03650.8 KFH46897.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0041) PHD PF00628.24 KFH46898.1 - 3.1e-09 36.3 1.1 7.9e-09 35.0 0.7 1.7 1 0 0 1 1 1 1 PHD-finger UIM PF02809.15 KFH46898.1 - 0.0045 16.4 0.7 0.023 14.2 0.5 2.3 1 0 0 1 1 1 1 Ubiquitin interaction motif PHD_2 PF13831.1 KFH46898.1 - 0.016 14.5 2.0 0.026 13.8 1.4 1.4 1 0 0 1 1 1 0 PHD-finger E1-E2_ATPase PF00122.15 KFH46899.1 - 2.5e-16 59.4 0.0 1e-15 57.4 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KFH46899.1 - 5.6e-15 56.3 0.0 7.8e-14 52.5 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFH46899.1 - 6.5e-10 39.4 0.0 1.6e-09 38.2 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFH46899.1 - 0.00029 20.7 0.0 0.0011 18.8 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFH46899.1 - 0.0017 18.0 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase TrmE_N PF10396.4 KFH46900.1 - 3.8e-34 117.0 0.0 8.1e-34 116.0 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 KFH46900.1 - 1.2e-22 80.1 1.9 3.1e-22 78.7 0.2 2.6 2 1 0 2 2 2 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 KFH46900.1 - 1.4e-16 60.4 0.0 3e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFH46900.1 - 6.6e-05 22.2 0.0 0.00023 20.5 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KFH46900.1 - 0.0005 19.9 0.0 0.002 17.9 0.0 2.1 2 1 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.22 KFH46900.1 - 0.0058 16.0 0.0 0.052 12.9 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 KFH46900.1 - 0.024 15.1 0.0 0.14 12.6 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein cobW PF02492.14 KFH46900.1 - 0.062 12.7 0.4 0.33 10.3 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 KFH46900.1 - 0.091 11.9 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 KFH46900.1 - 0.11 12.8 0.0 0.25 11.6 0.0 1.7 2 0 0 2 2 2 0 ABC transporter DUF3425 PF11905.3 KFH46901.1 - 1.5e-33 115.5 0.1 2.3e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) DLH PF01738.13 KFH46903.1 - 2.6e-20 72.6 0.0 3e-20 72.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KFH46903.1 - 5.6e-08 32.6 0.0 7.1e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFH46903.1 - 0.013 15.3 0.0 0.034 14.0 0.1 1.6 1 1 1 2 2 2 0 Alpha/beta hydrolase family Glyco_hydro_63 PF03200.11 KFH46904.1 - 5.1e-240 798.5 0.1 5.3e-239 795.2 0.1 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 KFH46904.1 - 3.8e-09 35.7 0.1 6.9e-09 34.8 0.1 1.3 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.9 KFH46904.1 - 0.0048 15.6 0.0 0.0091 14.7 0.0 1.5 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Vps55 PF04133.9 KFH46905.1 - 4.3e-46 155.5 7.5 4.8e-46 155.4 5.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Proteasome PF00227.21 KFH46907.1 - 2.2e-43 147.7 0.1 2.9e-43 147.3 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KFH46907.1 - 6.9e-11 41.2 0.2 1.1e-10 40.6 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature adh_short_C2 PF13561.1 KFH46908.1 - 8.6e-09 35.5 0.0 1.2e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFH46908.1 - 7e-08 32.5 0.0 1.3e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH46908.1 - 0.018 14.7 0.0 0.056 13.1 0.0 1.8 1 1 0 1 1 1 0 KR domain DUF1776 PF08643.5 KFH46908.1 - 0.079 12.0 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) WD40 PF00400.27 KFH46909.1 - 6.2e-20 70.2 9.9 0.00037 20.2 0.0 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat DUF2264 PF10022.4 KFH46910.1 - 4.2e-123 410.5 0.7 4.1e-85 285.6 2.2 2.1 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2264) Surf_Ag_VNR PF07244.10 KFH46910.1 - 0.023 15.0 0.0 0.056 13.8 0.0 1.6 1 0 0 1 1 1 0 Surface antigen variable number repeat Peptidase_S58 PF03576.9 KFH46911.1 - 2.5e-82 276.6 0.2 2.9e-82 276.5 0.1 1.0 1 0 0 1 1 1 1 Peptidase family S58 Elong_Iki1 PF10483.4 KFH46913.1 - 4.6e-80 268.9 0.0 5.4e-80 268.7 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 NDK PF00334.14 KFH46914.1 - 1.7e-55 186.5 0.0 2.1e-55 186.2 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase HAD_2 PF13419.1 KFH46915.1 - 6.7e-18 65.5 0.0 1.1e-17 64.8 0.0 1.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFH46915.1 - 3.7e-08 32.9 0.0 6.3e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KFH46915.1 - 3.9e-06 27.4 0.1 3.2e-05 24.4 0.0 2.3 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase NIF PF03031.13 KFH46915.1 - 0.00096 18.8 0.0 0.098 12.3 0.0 2.2 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Oxidored_nitro PF00148.14 KFH46915.1 - 0.0025 16.5 0.0 0.003 16.2 0.0 1.2 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase CTP_synth_N PF06418.9 KFH46916.1 - 6.7e-101 336.9 0.0 1.3e-100 336.0 0.0 1.4 1 1 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 KFH46916.1 - 2.2e-49 167.5 0.0 3.7e-49 166.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KFH46916.1 - 0.00038 19.9 0.0 0.00068 19.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 ArsA_ATPase PF02374.10 KFH46916.1 - 0.038 13.0 0.2 0.069 12.1 0.1 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase CbiA PF01656.18 KFH46916.1 - 0.088 12.2 0.1 0.19 11.1 0.1 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain FH2 PF02181.18 KFH46917.1 - 4.3e-81 272.6 5.5 4.3e-81 272.6 3.8 1.6 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 KFH46917.1 - 4.6e-60 202.2 0.0 1.4e-59 200.6 0.0 1.9 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 KFH46917.1 - 1.4e-52 177.9 2.0 1.2e-51 174.9 1.0 2.6 1 1 1 2 2 2 1 Diaphanous FH3 Domain Aminotran_5 PF00266.14 KFH46918.1 - 5.6e-32 110.8 0.0 9.2e-21 73.9 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Mso1_Sec1_bdg PF14475.1 KFH46919.1 - 3.6e-20 71.0 0.1 5.8e-20 70.4 0.0 1.3 1 0 0 1 1 1 1 Sec1-binding region of Mso1 GFO_IDH_MocA PF01408.17 KFH46920.1 - 8.8e-10 39.1 0.0 1.7e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold AA_permease PF00324.16 KFH46921.1 - 2.5e-55 187.7 24.9 3.2e-55 187.3 17.3 1.1 1 0 0 1 1 1 1 Amino acid permease Ank_4 PF13637.1 KFH46922.1 - 9.4e-28 96.0 1.2 6.9e-09 35.9 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 KFH46922.1 - 3.6e-25 88.1 0.0 1.6e-14 54.0 0.0 2.9 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFH46922.1 - 1.1e-23 81.8 2.5 1.6e-08 33.9 0.0 5.9 5 1 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.1 KFH46922.1 - 1.4e-17 61.9 0.1 0.00075 19.5 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 KFH46922.1 - 2.9e-17 62.2 0.9 5.2e-09 36.0 0.1 2.9 2 2 0 2 2 2 2 Ankyrin repeats (many copies) Pkinase PF00069.20 KFH46923.1 - 3.7e-73 245.8 1.0 2e-36 125.4 0.0 4.8 4 1 0 4 4 4 3 Protein kinase domain HGTP_anticodon2 PF12745.2 KFH46923.1 - 9.4e-69 231.5 2.9 9.4e-69 231.5 2.0 2.4 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.12 KFH46923.1 - 6.9e-47 159.6 0.0 6.6e-22 77.8 0.0 3.5 3 0 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.1 KFH46923.1 - 3e-20 72.5 0.0 8.6e-20 71.0 0.0 1.8 1 0 0 1 1 1 1 Histidyl-tRNA synthetase RWD PF05773.17 KFH46923.1 - 6e-15 55.1 0.0 1.6e-14 53.7 0.0 1.8 1 0 0 1 1 1 1 RWD domain APH PF01636.18 KFH46923.1 - 3.9e-09 36.5 1.3 0.003 17.3 0.0 3.4 3 0 0 3 3 3 2 Phosphotransferase enzyme family DUF1682 PF07946.9 KFH46923.1 - 0.69 8.6 14.1 1.2 7.9 9.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Hus1 PF04005.7 KFH46924.1 - 6.5e-95 317.4 0.0 7.9e-95 317.1 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein MFS_1 PF07690.11 KFH46925.1 - 3.4e-25 88.5 43.0 2.8e-20 72.3 12.3 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily OATP PF03137.15 KFH46925.1 - 0.0076 14.3 0.0 0.014 13.4 0.0 1.5 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Acyl-CoA_dh_1 PF00441.19 KFH46926.1 - 2.7e-42 144.3 0.8 7.1e-42 143.0 0.6 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFH46926.1 - 8.2e-34 116.5 0.1 1.7e-33 115.5 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KFH46926.1 - 7.3e-20 70.2 0.1 1.6e-19 69.1 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KFH46926.1 - 1.5e-13 51.1 0.1 4.1e-13 49.7 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 KFH46926.1 - 0.0036 16.7 0.2 0.016 14.6 0.1 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal AhpC-TSA PF00578.16 KFH46926.1 - 0.017 14.8 0.1 0.18 11.4 0.0 2.1 2 0 0 2 2 2 0 AhpC/TSA family Glyco_hydro_3 PF00933.16 KFH46927.1 - 1.2e-60 205.0 0.0 2.2e-60 204.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KFH46927.1 - 2.6e-38 131.8 0.0 3.7e-38 131.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Ank_2 PF12796.2 KFH46928.1 - 0.00042 20.5 0.0 0.098 13.0 0.0 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KFH46928.1 - 0.0061 16.6 0.2 12 6.4 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeat Ank PF00023.25 KFH46928.1 - 0.023 14.5 0.2 36 4.4 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat F-box-like PF12937.2 KFH46928.1 - 0.028 14.1 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 F-box-like Ank_4 PF13637.1 KFH46928.1 - 0.086 13.3 0.0 2.5 8.7 0.0 2.5 1 1 2 3 3 3 0 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFH46928.1 - 0.12 12.6 0.1 18 5.7 0.0 2.7 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Cut12 PF11500.3 KFH46929.1 - 3e-39 134.1 15.8 3e-39 134.1 11.0 3.5 1 1 1 2 2 2 1 Spindle pole body formation-associated protein Pox_A_type_inc PF04508.7 KFH46929.1 - 3.9 7.5 22.2 0.14 12.0 0.4 6.2 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat UBA_4 PF14555.1 KFH46930.1 - 0.003 17.0 0.1 0.0079 15.7 0.1 1.7 1 0 0 1 1 1 1 UBA-like domain DUF1796 PF08795.5 KFH46930.1 - 0.13 11.9 0.4 0.26 10.8 0.3 1.5 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) UIM PF02809.15 KFH46930.1 - 6.7 6.5 8.0 16 5.4 4.6 2.5 2 0 0 2 2 2 0 Ubiquitin interaction motif 2OG-FeII_Oxy_4 PF13661.1 KFH46931.1 - 0.0073 15.9 0.4 0.025 14.2 0.1 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily HET PF06985.6 KFH46932.1 - 2.5e-13 50.3 0.2 6.5e-13 49.0 0.1 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) BRCT PF00533.21 KFH46933.1 - 2.8e-06 27.3 0.0 8.7e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain EamA PF00892.15 KFH46934.1 - 1.1e-10 41.6 28.8 5.3e-09 36.1 0.8 3.0 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.6 KFH46934.1 - 1.4e-07 30.7 9.4 1.6e-07 30.5 5.1 1.8 2 0 0 2 2 2 1 UAA transporter family DUF914 PF06027.7 KFH46934.1 - 3.5e-06 26.1 4.6 6.2e-06 25.2 3.2 1.4 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) TPT PF03151.11 KFH46934.1 - 1.8e-05 24.4 1.0 1.8e-05 24.4 0.7 2.9 3 0 0 3 3 3 2 Triose-phosphate Transporter family EmrE PF13536.1 KFH46934.1 - 0.00054 20.1 3.5 0.00054 20.1 2.4 3.1 3 1 0 3 3 3 1 Multidrug resistance efflux transporter TOM_sub5 PF15178.1 KFH46934.1 - 0.032 13.9 0.0 0.13 11.9 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial import receptor subunit TOM5 homolog Sugar_tr PF00083.19 KFH46935.1 - 4.7e-82 275.9 28.1 5.6e-82 275.7 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH46935.1 - 1.8e-15 56.5 33.9 1.9e-14 53.1 20.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Spo12 PF05032.7 KFH46937.1 - 1.7e-13 49.9 0.4 1.7e-13 49.9 0.3 1.9 2 0 0 2 2 2 1 Spo12 family GSHPx PF00255.14 KFH46938.1 - 1.1e-42 143.8 0.0 1.4e-42 143.4 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.5 KFH46938.1 - 0.00044 19.8 0.1 0.00057 19.4 0.0 1.3 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KFH46938.1 - 0.004 16.8 0.0 0.0057 16.3 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family DUF4174 PF13778.1 KFH46938.1 - 0.0068 16.4 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) hEGF PF12661.2 KFH46939.1 - 0.0098 15.9 2.6 0.028 14.4 1.8 1.9 1 0 0 1 1 1 1 Human growth factor-like EGF EGF_2 PF07974.8 KFH46939.1 - 0.54 10.4 11.6 1.1 9.4 8.0 1.6 1 0 0 1 1 1 0 EGF-like domain EGF_alliinase PF04863.8 KFH46939.1 - 4.3 7.3 8.0 12 5.9 5.5 1.8 1 0 0 1 1 1 0 Alliinase EGF-like domain RRM_1 PF00076.17 KFH46940.1 - 2.9e-08 33.2 0.0 5.2e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH46940.1 - 1.6e-06 27.8 0.0 4.1e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH46940.1 - 4e-05 23.4 0.0 8.1e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFH46940.1 - 0.0012 18.5 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif MMR_HSR1 PF01926.18 KFH46941.1 - 2.2e-14 53.3 0.0 5.5e-14 52.1 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 KFH46941.1 - 9.2e-06 24.9 0.1 1.7e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 KFH46941.1 - 0.001 18.4 0.3 0.0025 17.1 0.2 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KFH46941.1 - 0.0013 18.6 0.1 0.56 10.0 0.0 2.5 1 1 1 2 2 2 2 Dynamin family AAA_16 PF13191.1 KFH46941.1 - 0.0034 17.3 0.2 0.0084 16.1 0.1 1.6 2 0 0 2 2 2 1 AAA ATPase domain AIG1 PF04548.11 KFH46941.1 - 0.0047 16.0 0.1 0.009 15.1 0.0 1.5 1 0 0 1 1 1 1 AIG1 family AAA_18 PF13238.1 KFH46941.1 - 0.027 14.7 0.0 0.059 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 KFH46941.1 - 0.065 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_29 PF13555.1 KFH46941.1 - 0.1 12.1 0.2 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 KFH46941.1 - 0.11 13.3 0.3 0.35 11.6 0.1 2.0 2 0 0 2 2 2 0 AAA domain Nop16 PF09420.5 KFH46942.1 - 5.6e-49 166.3 7.6 7.1e-49 166.0 5.2 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 GDA1_CD39 PF01150.12 KFH46943.1 - 3.6e-98 328.9 0.0 4.5e-98 328.5 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Lysine_decarbox PF03641.9 KFH46944.1 - 6.6e-30 103.6 0.0 9.3e-30 103.1 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase DUF1205 PF06722.7 KFH46944.1 - 0.087 13.0 0.0 0.21 11.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1205) Ras PF00071.17 KFH46945.1 - 9.5e-57 190.8 0.0 1.1e-56 190.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFH46945.1 - 2.1e-18 66.9 0.0 3.2e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFH46945.1 - 1.1e-14 53.9 0.0 1.3e-14 53.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFH46945.1 - 1.8e-07 30.7 0.0 4.1e-06 26.3 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFH46945.1 - 1.9e-07 31.0 0.0 2.6e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFH46945.1 - 2e-07 30.4 0.0 2.4e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 KFH46945.1 - 0.00073 19.6 0.0 0.0014 18.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KFH46945.1 - 0.0011 18.2 0.1 0.002 17.3 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SRPRB PF09439.5 KFH46945.1 - 0.0017 17.6 0.0 0.0026 17.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KFH46945.1 - 0.0034 16.8 0.0 0.056 12.9 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 KFH46945.1 - 0.0038 16.8 0.2 0.14 11.6 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 KFH46945.1 - 0.0041 16.8 0.3 0.0076 15.9 0.0 1.5 2 0 0 2 2 2 1 Archaeal ATPase AAA_16 PF13191.1 KFH46945.1 - 0.0043 17.0 0.0 0.014 15.3 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 KFH46945.1 - 0.0062 16.1 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Septin PF00735.13 KFH46945.1 - 0.0062 15.5 0.1 0.014 14.4 0.0 1.6 1 0 0 1 1 1 1 Septin AAA_10 PF12846.2 KFH46945.1 - 0.007 15.8 0.2 0.011 15.1 0.1 1.5 1 1 0 1 1 1 1 AAA-like domain cobW PF02492.14 KFH46945.1 - 0.01 15.2 0.0 0.024 14.0 0.0 1.5 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 KFH46945.1 - 0.031 13.9 0.1 0.072 12.7 0.0 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 KFH46945.1 - 0.032 13.9 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.9 KFH46945.1 - 0.048 13.3 0.0 0.17 11.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) FeoB_N PF02421.13 KFH46945.1 - 0.053 12.7 0.0 0.8 8.9 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B RNA_helicase PF00910.17 KFH46945.1 - 0.083 13.0 0.0 0.33 11.1 0.0 1.9 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.7 KFH46945.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 KFH46945.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain FAD_binding_6 PF00970.19 KFH46946.1 - 3.4e-07 30.3 0.0 3.1e-06 27.2 0.0 2.5 4 0 0 4 4 4 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KFH46946.1 - 0.00042 20.8 0.0 0.0035 17.8 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KFH46946.1 - 0.035 14.0 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Glyco_hydro_18 PF00704.23 KFH46947.1 - 6.4e-16 58.7 0.3 3.1e-14 53.1 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.8 KFH46947.1 - 0.069 12.2 0.0 0.095 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 Rho_RNA_bind PF07497.7 KFH46947.1 - 0.093 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Rho termination factor, RNA-binding domain Ribosomal_L28e PF01778.12 KFH46949.1 - 7.7e-32 110.1 1.9 7.7e-32 110.1 1.3 1.7 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 KFH46949.1 - 7.3e-21 74.1 26.5 7.3e-21 74.1 18.3 3.3 1 1 1 2 2 2 1 Mak16 protein C-terminal region TFIIA PF03153.8 KFH46949.1 - 0.00058 19.8 7.9 0.00069 19.6 5.5 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 KFH46949.1 - 0.0096 13.9 31.7 0.013 13.5 22.0 1.1 1 0 0 1 1 1 1 Nop14-like family TFIIF_alpha PF05793.7 KFH46949.1 - 0.089 11.1 25.4 0.12 10.7 17.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PYC_OADA PF02436.13 KFH46949.1 - 0.11 11.8 1.2 0.21 11.0 0.6 1.5 1 1 0 1 1 1 0 Conserved carboxylase domain PPP4R2 PF09184.6 KFH46949.1 - 7 6.1 22.0 9.8 5.6 15.3 1.2 1 0 0 1 1 1 0 PPP4R2 PetN PF03742.9 KFH46950.1 - 0.026 14.0 0.0 0.026 14.0 0.0 2.2 3 0 0 3 3 3 0 PetN Integrase_AP2 PF14657.1 KFH46950.1 - 0.23 11.2 4.1 3.1 7.6 0.2 2.2 2 0 0 2 2 2 0 AP2-like DNA-binding integrase domain Zn_clus PF00172.13 KFH46951.1 - 0.0021 17.9 15.6 0.0021 17.9 10.8 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TBD PF12845.2 KFH46951.1 - 0.066 12.7 0.8 0.69 9.5 0.1 2.4 2 0 0 2 2 2 0 TBD domain TRAPPC9-Trs120 PF08626.6 KFH46952.1 - 6.3e-138 461.0 0.0 6.7e-114 381.4 0.0 2.2 2 0 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TFIIE-A_C-term PF11521.3 KFH46953.1 - 1.6 8.6 5.2 1 9.3 0.1 2.7 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha HCO3_cotransp PF00955.16 KFH46954.1 - 1.9e-49 168.6 9.4 7.3e-26 90.8 0.1 2.1 1 1 1 2 2 2 2 HCO3- transporter family Sugar_tr PF00083.19 KFH46956.1 - 3.5e-119 398.3 28.5 4e-119 398.1 19.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH46956.1 - 2.8e-25 88.7 23.8 2.8e-25 88.7 16.5 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily COPIIcoated_ERV PF07970.7 KFH46957.1 - 8.5e-39 133.4 0.1 1.2e-38 132.9 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KFH46957.1 - 1.3e-17 63.5 0.0 2.4e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) ASXH PF13919.1 KFH46958.1 - 9.4e-25 87.0 0.1 1.6e-24 86.3 0.1 1.4 1 0 0 1 1 1 1 Asx homology domain SRP-alpha_N PF04086.8 KFH46958.1 - 5.1 6.3 7.3 0.45 9.8 0.4 2.0 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal GATase_4 PF13230.1 KFH46959.1 - 2e-17 62.8 0.1 2.1e-15 56.1 0.1 2.1 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 KFH46959.1 - 2.9e-10 40.2 0.0 5.1e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 KFH46959.1 - 9.2e-07 27.8 0.2 9.5e-05 21.2 0.1 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II Sec16_C PF12931.2 KFH46960.1 - 5.6e-90 301.9 0.0 7.5e-90 301.5 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 KFH46960.1 - 5.5e-29 100.5 0.0 1e-28 99.6 0.0 1.5 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Longin PF13774.1 KFH46961.1 - 2.8e-26 90.8 0.1 4.1e-26 90.3 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 KFH46961.1 - 2.1e-15 56.0 0.0 1.6e-14 53.2 0.0 2.0 2 0 0 2 2 2 1 Synaptobrevin DUF1664 PF07889.7 KFH46961.1 - 0.066 13.0 0.1 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CAF1A PF12253.3 KFH46962.1 - 1.5e-18 66.6 3.4 1.5e-18 66.6 2.3 2.9 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A DUF3582 PF12122.3 KFH46962.1 - 0.11 12.4 1.5 0.63 10.0 1.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3582) MAP7 PF05672.6 KFH46962.1 - 0.99 8.7 48.3 0.042 13.2 26.1 3.0 3 0 0 3 3 3 0 MAP7 (E-MAP-115) family CAF-1_p150 PF11600.3 KFH46962.1 - 4 6.7 79.4 0.021 14.2 45.2 2.7 1 1 1 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Raftlin PF15250.1 KFH46962.1 - 6.6 5.1 17.0 11 4.3 11.8 1.4 1 0 0 1 1 1 0 Raftlin Oxidored_FMN PF00724.15 KFH46963.1 - 3.5e-80 269.5 0.0 5.2e-80 268.9 0.0 1.3 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family cobW PF02492.14 KFH46965.1 - 4.6e-38 130.4 0.0 1.4e-37 128.8 0.0 1.7 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 KFH46965.1 - 0.0017 18.0 0.0 0.0032 17.1 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 KFH46965.1 - 0.0048 16.6 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 KFH46965.1 - 0.014 14.9 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase CobW_C PF07683.9 KFH46965.1 - 0.027 14.1 0.0 0.17 11.6 0.0 2.4 2 1 0 2 2 2 0 Cobalamin synthesis protein cobW C-terminal domain AAA_10 PF12846.2 KFH46965.1 - 0.028 13.8 0.0 0.033 13.6 0.0 1.4 1 1 0 1 1 1 0 AAA-like domain AAA_14 PF13173.1 KFH46965.1 - 0.033 14.0 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KFH46965.1 - 0.041 13.4 0.1 0.51 9.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain NTPase_1 PF03266.10 KFH46965.1 - 0.046 13.4 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.1 KFH46965.1 - 0.068 13.3 0.0 0.15 12.1 0.0 1.6 2 0 0 2 2 1 0 AAA domain DUF2075 PF09848.4 KFH46965.1 - 0.098 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 KFH46965.1 - 0.12 12.7 0.5 0.29 11.4 0.3 1.8 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KFH46965.1 - 0.15 11.7 0.0 0.34 10.5 0.0 1.5 2 0 0 2 2 2 0 Archaeal ATPase Thioredoxin PF00085.15 KFH46966.1 - 5.2e-25 87.1 0.0 5.7e-25 87.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KFH46966.1 - 2.2e-09 37.3 0.0 3e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KFH46966.1 - 2.7e-07 30.7 0.5 2.8e-06 27.4 0.3 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KFH46966.1 - 4.6e-06 26.5 0.1 6.6e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 KFH46966.1 - 4.9e-05 22.9 0.1 7.7e-05 22.3 0.1 1.3 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 KFH46966.1 - 0.0021 17.5 0.0 0.0026 17.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 KFH46966.1 - 0.0023 17.4 0.2 0.0047 16.4 0.1 1.4 1 1 1 2 2 2 1 Redoxin TraF PF13728.1 KFH46966.1 - 0.0074 15.7 0.1 0.011 15.1 0.0 1.3 1 1 0 1 1 1 1 F plasmid transfer operon protein HyaE PF07449.6 KFH46966.1 - 0.056 13.3 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 KFH46966.1 - 0.071 12.9 0.1 0.2 11.4 0.1 1.8 1 1 0 1 1 1 0 Thioredoxin domain Phosducin PF02114.11 KFH46966.1 - 0.082 11.6 0.0 0.095 11.4 0.0 1.1 1 0 0 1 1 1 0 Phosducin MS_channel PF00924.13 KFH46967.1 - 3.8e-19 68.8 0.9 7.2e-19 67.9 0.6 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_7 PF13499.1 KFH46967.1 - 0.0037 17.3 0.1 0.0037 17.3 0.1 2.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 KFH46967.1 - 0.0039 16.3 0.2 0.0092 15.2 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 KFH46967.1 - 0.008 15.4 0.1 0.019 14.3 0.1 1.6 1 0 0 1 1 1 1 EF hand WXG100 PF06013.7 KFH46967.1 - 0.011 15.7 0.7 0.38 10.7 0.1 2.6 2 0 0 2 2 2 0 Proteins of 100 residues with WXG EF-hand_6 PF13405.1 KFH46967.1 - 0.022 14.6 0.1 0.061 13.2 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain EF-hand_8 PF13833.1 KFH46967.1 - 0.025 14.2 0.0 0.066 12.8 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair OmdA PF13376.1 KFH46967.1 - 0.1 12.2 4.9 0.44 10.2 0.5 2.5 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated Init_tRNA_PT PF04179.7 KFH46968.1 - 2.3e-137 458.5 0.0 1.1e-136 456.2 0.0 1.8 1 1 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Aa_trans PF01490.13 KFH46969.1 - 3.7e-83 279.2 30.4 4.4e-83 279.0 21.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Suc_Fer-like PF06999.7 KFH46969.1 - 1.2e-46 159.6 0.0 1.7e-46 159.1 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Phage_CII PF05269.6 KFH46969.1 - 0.3 11.1 0.0 0.79 9.7 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage CII protein Glyco_hydro_76 PF03663.9 KFH46970.1 - 1.1e-142 475.8 7.8 1.3e-142 475.5 5.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 RabGAP-TBC PF00566.13 KFH46971.1 - 2.2e-36 125.3 4.7 4e-36 124.4 3.3 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 KFH46971.1 - 2.5e-09 36.7 0.0 7.3e-06 25.4 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF3548) COG4 PF08318.7 KFH46971.1 - 0.14 10.8 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 COG4 transport protein DHDPS PF00701.17 KFH46972.1 - 3.3e-34 117.8 0.0 4.2e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF1777 PF08648.7 KFH46973.1 - 4.3e-26 91.7 33.9 4.3e-26 91.7 23.5 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1777) NAC PF01849.13 KFH46974.1 - 8.6e-26 89.2 0.5 7.7e-25 86.1 0.1 2.2 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 KFH46974.1 - 0.0021 17.8 0.2 0.0021 17.8 0.1 2.4 3 0 0 3 3 3 1 UBA/TS-N domain Myc_N PF01056.13 KFH46974.1 - 6.1 5.9 10.6 0.5 9.4 3.0 1.9 2 0 0 2 2 2 0 Myc amino-terminal region FAM176 PF14851.1 KFH46974.1 - 6.9 6.3 9.3 7 6.3 1.9 2.2 2 0 0 2 2 2 0 FAM176 family Pkinase PF00069.20 KFH46975.1 - 3.9e-54 183.5 0.0 5.7e-54 183.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH46975.1 - 1e-25 90.3 0.1 2.7e-25 88.9 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH46975.1 - 0.28 10.1 0.0 0.54 9.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Fungal_trans PF04082.13 KFH46976.1 - 1.3e-21 76.6 0.4 1.6e-21 76.4 0.3 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Autophagy_N PF03986.8 KFH46977.1 - 3e-47 160.0 1.5 3e-47 160.0 0.1 1.6 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 KFH46977.1 - 6.6e-23 80.6 0.2 1.3e-22 79.7 0.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 KFH46977.1 - 1.4e-14 52.8 0.4 2.5e-14 52.0 0.3 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Pro_isomerase PF00160.16 KFH46978.1 - 9.4e-51 172.0 0.0 1e-50 171.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD AdoMet_MTase PF07757.8 KFH46979.1 - 2.3e-39 133.9 0.0 4e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.1 KFH46979.1 - 0.0065 16.1 0.0 0.04 13.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH46979.1 - 0.011 15.4 0.0 0.027 14.2 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 KFH46979.1 - 0.041 14.4 0.0 0.13 12.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Mcp5_PH PF12814.2 KFH46980.1 - 8e-44 148.4 1.1 9.8e-44 148.2 0.0 1.7 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology CFEM PF05730.6 KFH46981.1 - 2.6e-09 36.7 9.9 3.3e-09 36.4 6.8 1.1 1 0 0 1 1 1 1 CFEM domain EB PF01683.13 KFH46981.1 - 0.58 10.2 5.3 0.87 9.6 3.7 1.3 1 0 0 1 1 1 0 EB module Methyltransf_16 PF10294.4 KFH46982.1 - 2.8e-16 59.4 0.0 4.5e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KFH46982.1 - 7.4e-10 39.4 0.0 1.6e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFH46982.1 - 5.2e-05 23.2 0.2 0.00012 22.0 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH46982.1 - 8e-05 22.2 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH46982.1 - 0.00017 22.0 0.0 0.00032 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFH46982.1 - 0.00051 19.4 0.0 0.0014 18.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_11 PF08241.7 KFH46982.1 - 0.0016 18.8 0.0 0.0031 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH46982.1 - 0.0078 15.9 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFH46982.1 - 0.016 14.3 0.0 0.029 13.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.7 KFH46982.1 - 0.019 14.5 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_32 PF13679.1 KFH46982.1 - 0.07 12.8 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 KFH46982.1 - 0.12 11.9 0.0 0.29 10.6 0.0 1.6 1 1 1 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Abhydrolase_6 PF12697.2 KFH46983.1 - 1.1e-26 94.1 5.2 1.3e-26 93.9 3.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH46983.1 - 9.6e-13 48.1 0.2 2.3e-12 46.8 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFH46983.1 - 3.5e-12 46.3 0.2 1.8e-11 44.0 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 KFH46983.1 - 1.1e-07 31.4 0.2 0.00013 21.3 0.0 2.3 2 1 0 2 2 2 2 Dienelactone hydrolase family DUF2048 PF09752.4 KFH46983.1 - 4.7e-05 22.4 0.0 5.4e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Peptidase_S15 PF02129.13 KFH46983.1 - 0.00015 21.3 0.0 0.00023 20.7 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Thioesterase PF00975.15 KFH46983.1 - 0.00015 22.0 0.0 0.00022 21.5 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain FSH1 PF03959.8 KFH46983.1 - 0.00025 20.5 0.2 0.0052 16.2 0.2 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) BAAT_C PF08840.6 KFH46983.1 - 0.00053 19.7 0.1 0.0036 17.0 0.1 2.0 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal PGAP1 PF07819.8 KFH46983.1 - 0.00056 19.5 0.0 0.0078 15.8 0.0 2.0 2 0 0 2 2 2 1 PGAP1-like protein Peptidase_S9 PF00326.16 KFH46983.1 - 0.00096 18.4 1.1 0.014 14.6 0.1 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family PhoPQ_related PF10142.4 KFH46983.1 - 0.0018 16.8 0.1 0.0026 16.3 0.0 1.3 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Abhydrolase_3 PF07859.8 KFH46983.1 - 0.0031 17.1 0.6 0.014 14.9 0.4 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KFH46983.1 - 0.015 14.7 0.0 0.91 8.9 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.15 KFH46983.1 - 0.05 13.0 0.1 0.075 12.4 0.1 1.5 1 1 0 1 1 1 0 Putative esterase DUF2974 PF11187.3 KFH46983.1 - 0.05 12.9 0.0 0.084 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) WD40 PF00400.27 KFH46985.1 - 1.6e-24 84.7 14.8 3.8e-09 36.0 0.3 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KFH46985.1 - 3.6e-05 22.2 1.3 0.0023 16.3 0.0 3.3 2 1 3 5 5 5 1 Cytochrome D1 heme domain PQQ_3 PF13570.1 KFH46985.1 - 0.012 15.8 0.3 0.84 9.9 0.0 2.9 2 0 0 2 2 2 0 PQQ-like domain PD40 PF07676.7 KFH46985.1 - 0.24 11.1 0.0 0.24 11.1 0.0 2.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Daxx PF03344.10 KFH46985.1 - 9.2 4.6 8.7 12 4.1 6.1 1.1 1 0 0 1 1 1 0 Daxx Family HeLo PF14479.1 KFH46988.1 - 3.1e-16 59.7 3.0 8e-12 45.3 0.2 2.4 1 1 1 2 2 2 2 Prion-inhibition and propagation NACHT PF05729.7 KFH46988.1 - 2e-09 37.3 0.0 4.8e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KFH46988.1 - 1.5e-06 28.3 1.0 3.2e-05 23.9 0.0 3.1 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 KFH46988.1 - 0.00074 19.6 0.0 0.0026 17.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KFH46988.1 - 0.0039 16.3 0.0 0.0077 15.3 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA PF00004.24 KFH46988.1 - 0.0052 16.9 0.0 0.026 14.7 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KFH46988.1 - 0.0099 14.7 0.1 0.045 12.6 0.1 2.1 1 1 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.17 KFH46988.1 - 0.011 15.8 0.0 0.028 14.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 KFH46988.1 - 0.017 14.8 0.0 0.073 12.8 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain Soyouz_module PF14313.1 KFH46988.1 - 0.022 14.3 0.0 0.053 13.0 0.0 1.6 1 0 0 1 1 1 0 N-terminal region of Paramyxovirinae phosphoprotein (P) AAA_11 PF13086.1 KFH46988.1 - 0.033 13.7 0.0 0.093 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 KFH46988.1 - 0.036 13.7 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 KFH46988.1 - 0.041 13.2 0.0 0.13 11.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain Sfi1 PF08457.5 KFH46988.1 - 0.043 12.2 0.0 0.043 12.2 0.0 1.7 3 0 0 3 3 3 0 Sfi1 spindle body protein AAA_14 PF13173.1 KFH46988.1 - 0.054 13.4 0.0 0.3 11.0 0.0 2.3 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KFH46988.1 - 0.07 12.8 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Archaeal ATPase Aminotran_1_2 PF00155.16 KFH46989.1 - 9.2e-42 143.2 0.0 1.1e-41 142.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II zf-ZPR1 PF03367.8 KFH46990.1 - 0.075 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 ZPR1 zinc-finger domain zf-DHHC PF01529.15 KFH46991.1 - 1.2e-08 34.5 20.9 2e-08 33.8 8.0 3.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase ISK_Channel PF02060.10 KFH46991.1 - 0.13 11.8 0.4 0.36 10.4 0.2 1.7 2 0 0 2 2 2 0 Slow voltage-gated potassium channel ABC2_membrane_3 PF12698.2 KFH46991.1 - 0.29 10.1 7.2 0.16 10.9 0.8 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein 5TM-5TMR_LYT PF07694.7 KFH46991.1 - 2.7 7.3 8.5 1.3 8.2 0.5 2.3 2 1 0 2 2 2 0 5TMR of 5TMR-LYT Peptidase_A22B PF04258.8 KFH46992.1 - 2.2e-44 152.1 9.7 3.3e-43 148.2 6.7 2.4 1 1 0 1 1 1 1 Signal peptide peptidase PBP1_TM PF14812.1 KFH46992.1 - 0.2 11.9 7.5 1.5 9.1 0.0 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.1 KFH46992.1 - 0.63 9.7 2.1 8 6.1 0.0 2.4 2 0 0 2 2 2 0 FAM176 family Slu7 PF11708.3 KFH46993.1 - 7.7e-74 248.4 18.0 7.7e-74 248.4 12.5 2.4 3 0 0 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 KFH46993.1 - 0.018 14.6 0.6 0.039 13.6 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF3128 PF11326.3 KFH46993.1 - 0.38 10.8 0.1 0.38 10.8 0.1 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3128) DUF2076 PF09849.4 KFH46994.1 - 2.5e-08 34.2 12.4 3e-08 34.0 8.6 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 KFH46994.1 - 0.00021 21.1 4.5 0.00022 21.0 2.5 1.5 1 1 1 2 2 2 2 CHCH domain GCK PF07802.6 KFH46994.1 - 0.052 13.6 0.2 0.08 13.0 0.1 1.3 1 0 0 1 1 1 0 GCK domain DUF605 PF04652.11 KFH46994.1 - 0.22 10.9 9.4 0.26 10.6 6.5 1.1 1 0 0 1 1 1 0 Vta1 like WD40 PF00400.27 KFH46995.1 - 8e-09 35.0 6.4 6.7e-06 25.7 0.4 5.5 6 0 0 6 6 6 2 WD domain, G-beta repeat RWD PF05773.17 KFH46995.1 - 0.00032 20.5 0.0 0.00069 19.4 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.1 KFH46995.1 - 0.1 12.4 6.7 0.22 11.3 4.6 1.5 1 0 0 1 1 1 0 Ring finger domain DLH PF01738.13 KFH46996.1 - 1.8e-13 50.2 0.0 2.2e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 KFH46996.1 - 0.0071 16.2 0.0 0.0097 15.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH46996.1 - 0.011 15.4 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ribosomal_L21e PF01157.13 KFH46997.1 - 5.1e-39 132.0 5.0 5.1e-39 132.0 3.5 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e DUF3865 PF12981.2 KFH46997.1 - 0.014 15.2 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3865) Nexin_C PF08628.7 KFH46997.1 - 0.1 12.6 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Sorting nexin C terminal SET PF00856.23 KFH46998.1 - 1.3e-10 41.7 0.0 1.8e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 SET domain DUF1338 PF07063.8 KFH46998.1 - 0.053 12.5 0.0 0.18 10.8 0.0 1.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1338) Cupin_2 PF07883.6 KFH46999.1 - 0.039 13.4 0.2 0.056 12.9 0.1 1.2 1 0 0 1 1 1 0 Cupin domain ERG2_Sigma1R PF04622.7 KFH46999.1 - 0.12 11.6 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 ERG2 and Sigma1 receptor like protein HATPase_c PF02518.21 KFH47000.1 - 8.5e-23 80.1 0.0 2e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 KFH47000.1 - 7.5e-19 68.0 0.0 1.2e-08 35.2 0.0 3.6 3 0 0 3 3 3 3 PAS domain Response_reg PF00072.19 KFH47000.1 - 3.9e-16 59.0 0.0 1.6e-11 44.2 0.0 2.9 3 0 0 3 3 3 2 Response regulator receiver domain PAS_3 PF08447.6 KFH47000.1 - 1.4e-12 47.5 0.0 3.3e-05 23.9 0.0 3.7 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.1 KFH47000.1 - 1.3e-11 43.9 0.0 1.7e-05 24.4 0.0 3.7 3 0 0 3 3 3 2 PAS domain HisKA PF00512.20 KFH47000.1 - 6.8e-07 29.1 3.3 2.2e-06 27.5 0.5 3.0 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 KFH47000.1 - 4.2e-06 26.5 0.0 0.022 14.5 0.0 3.9 4 0 0 4 4 4 2 PAS fold PAS_4 PF08448.5 KFH47000.1 - 0.00046 20.1 0.0 12 6.0 0.0 4.6 4 0 0 4 4 4 1 PAS fold PAS_7 PF12860.2 KFH47000.1 - 0.054 13.5 0.5 1.4 8.9 0.0 3.4 4 0 0 4 4 4 0 PAS fold GAF_2 PF13185.1 KFH47000.1 - 0.096 13.1 0.1 0.89 10.0 0.0 2.6 3 0 0 3 3 3 0 GAF domain SecE PF00584.15 KFH47001.1 - 3.4e-09 36.1 0.0 4.2e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Coq4 PF05019.8 KFH47002.1 - 3.2e-98 327.0 0.0 4e-98 326.7 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 SUI1 PF01253.17 KFH47003.1 - 3.2e-29 100.5 6.5 4.2e-29 100.1 4.5 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Cas_Csa5 PF09702.5 KFH47003.1 - 0.11 12.5 0.5 0.31 11.1 0.1 1.8 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Csa5) Mid2 PF04478.7 KFH47004.1 - 2.6e-08 33.4 1.3 3.6e-08 32.9 0.1 1.9 1 1 0 1 1 1 1 Mid2 like cell wall stress sensor SKG6 PF08693.5 KFH47004.1 - 0.0076 15.5 1.9 0.019 14.2 1.3 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM51 PF15345.1 KFH47004.1 - 0.017 14.7 2.9 0.029 14.0 0.0 2.3 1 1 1 2 2 2 0 Transmembrane protein 51 DUF1191 PF06697.7 KFH47004.1 - 0.081 11.7 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Polyketide_cyc2 PF10604.4 KFH47005.1 - 0.0034 17.5 0.0 0.047 13.8 0.0 2.1 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport NPP1 PF05630.6 KFH47006.1 - 1.3e-81 273.2 0.7 1.7e-81 272.9 0.5 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) G-alpha PF00503.15 KFH47007.1 - 1.6e-34 119.2 0.0 4.9e-34 117.6 0.0 1.6 1 1 0 1 1 1 1 G-protein alpha subunit Zeta_toxin PF06414.7 KFH47007.1 - 0.00028 20.0 0.2 0.0007 18.7 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin ATP_bind_1 PF03029.12 KFH47007.1 - 0.00038 20.0 0.1 0.47 9.9 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 KFH47007.1 - 0.00077 19.3 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KFH47007.1 - 0.0095 15.4 0.0 0.38 10.1 0.0 2.7 3 0 0 3 3 3 1 AAA-like domain AAA_22 PF13401.1 KFH47007.1 - 0.015 15.4 0.0 0.027 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KFH47007.1 - 0.017 14.8 0.1 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KFH47007.1 - 0.033 15.0 0.0 0.11 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KFH47007.1 - 0.036 13.5 0.0 1.8 8.0 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_16 PF13191.1 KFH47007.1 - 0.044 13.7 0.0 0.086 12.8 0.0 1.6 2 0 0 2 2 1 0 AAA ATPase domain AAA PF00004.24 KFH47007.1 - 0.049 13.8 0.0 0.13 12.4 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 KFH47007.1 - 0.053 12.9 0.1 0.12 11.8 0.1 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MCM PF00493.18 KFH47007.1 - 0.055 12.2 0.0 0.073 11.8 0.0 1.1 1 0 0 1 1 1 0 MCM2/3/5 family NACHT PF05729.7 KFH47007.1 - 0.11 12.1 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 KFH47007.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 KFH47007.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFH47007.1 - 0.14 11.5 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KFH47007.1 - 0.15 11.6 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KFH47007.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KFH47007.1 - 0.16 11.0 0.0 0.28 10.1 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 KFH47007.1 - 0.16 11.5 0.0 0.38 10.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Med31 PF05669.7 KFH47008.1 - 3.2e-37 126.3 0.4 3.6e-37 126.2 0.3 1.0 1 0 0 1 1 1 1 SOH1 Herpes_U5 PF05999.6 KFH47008.1 - 0.25 9.8 1.2 0.32 9.5 0.3 1.5 1 1 1 2 2 2 0 Herpesvirus U5-like family RRM_1 PF00076.17 KFH47009.1 - 8.4e-20 70.1 0.0 1.8e-08 33.8 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH47009.1 - 2.1e-12 46.8 0.0 2.5e-05 24.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH47009.1 - 2.9e-09 36.6 0.1 0.0007 19.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SRP-alpha_N PF04086.8 KFH47010.1 - 2e-69 234.0 0.0 2.7e-69 233.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 KFH47010.1 - 4.5e-52 176.3 0.1 9.1e-52 175.3 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 KFH47010.1 - 5.2e-08 32.8 0.2 3.1e-07 30.4 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 KFH47010.1 - 3.8e-05 22.6 0.0 7.9e-05 21.5 0.0 1.5 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 KFH47010.1 - 4.9e-05 22.8 0.1 0.00013 21.4 0.1 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 KFH47010.1 - 0.0025 17.5 0.5 0.03 14.0 0.0 2.6 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 KFH47010.1 - 0.0029 17.2 0.1 0.0064 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KFH47010.1 - 0.0038 16.6 0.0 0.015 14.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KFH47010.1 - 0.0083 16.2 0.0 0.13 12.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KFH47010.1 - 0.01 15.3 0.0 0.048 13.0 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.18 KFH47010.1 - 0.026 14.4 0.0 0.061 13.2 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.1 KFH47010.1 - 0.046 13.5 0.0 0.18 11.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KFH47010.1 - 0.069 13.4 0.1 0.3 11.3 0.0 2.1 2 0 0 2 2 2 0 ABC transporter COX6A PF02046.10 KFH47011.1 - 1e-42 144.6 5.6 1.1e-42 144.5 3.9 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Exo_endo_phos_2 PF14529.1 KFH47012.1 - 4.4e-20 71.4 0.0 8.6e-20 70.5 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 KFH47012.1 - 2.2e-18 67.1 0.0 3.3e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.7 KFH47012.1 - 4.9e-05 23.1 1.2 0.00012 21.8 0.8 1.7 1 0 0 1 1 1 1 GRF zinc finger DAO PF01266.19 KFH47013.1 - 1.2e-64 218.5 0.1 1.7e-64 217.9 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T PF01571.16 KFH47013.1 - 1e-54 185.0 0.2 8.4e-53 178.8 0.1 2.2 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KFH47013.1 - 5.7e-18 64.7 0.2 1.7e-17 63.1 0.1 1.9 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Pyr_redox_3 PF13738.1 KFH47013.1 - 0.00019 21.5 0.0 0.00068 19.7 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFH47013.1 - 0.0006 20.1 0.2 0.052 13.9 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SoxG PF04268.7 KFH47013.1 - 0.001 18.9 0.0 0.11 12.3 0.0 2.6 3 0 0 3 3 2 1 Sarcosine oxidase, gamma subunit family ThiF PF00899.16 KFH47013.1 - 0.0038 17.0 0.1 0.008 16.0 0.0 1.5 1 0 0 1 1 1 1 ThiF family Trp_halogenase PF04820.9 KFH47013.1 - 0.0043 15.7 0.1 0.06 11.9 0.0 2.0 2 0 0 2 2 2 1 Tryptophan halogenase TrkA_N PF02254.13 KFH47013.1 - 0.0052 16.7 0.2 0.013 15.5 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain FAD_binding_3 PF01494.14 KFH47013.1 - 0.0089 15.1 0.4 0.82 8.6 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 KFH47013.1 - 0.0089 15.8 0.1 0.13 12.0 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KFH47013.1 - 0.016 14.1 0.3 0.048 12.4 0.2 1.7 1 1 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.1 KFH47013.1 - 0.034 14.1 0.0 0.099 12.6 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF4562 PF15123.1 KFH47013.1 - 0.043 13.6 0.5 0.96 9.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4562) Shikimate_DH PF01488.15 KFH47013.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GPI2 PF06432.6 KFH47015.1 - 3.6e-116 387.4 0.2 4.1e-116 387.2 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF4006 PF13179.1 KFH47015.1 - 0.048 13.2 0.2 0.12 11.8 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF4006) COPI_assoc PF08507.5 KFH47015.1 - 0.29 10.8 2.8 0.47 10.1 0.3 2.3 2 0 0 2 2 2 0 COPI associated protein MPC PF03650.8 KFH47016.1 - 7.2e-30 103.3 0.2 1.3e-29 102.6 0.2 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0041) MtN3_slv PF03083.11 KFH47016.1 - 0.04 13.7 0.2 0.058 13.2 0.2 1.2 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange DUF998 PF06197.8 KFH47016.1 - 0.048 12.9 0.2 0.065 12.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Herpes_glycop PF01528.11 KFH47016.1 - 0.087 11.4 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein M DUF1010 PF06231.6 KFH47016.1 - 0.12 12.4 0.8 0.23 11.4 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1010) CNH PF00780.17 KFH47017.1 - 4.2e-65 219.9 0.0 6.3e-65 219.3 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 KFH47017.1 - 2.8e-32 112.0 0.2 5.4e-32 111.1 0.2 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 KFH47017.1 - 2.5e-13 50.1 0.0 1.3e-12 47.8 0.0 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KFH47017.1 - 1.2e-05 25.4 0.0 3.2e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 PH domain IMS PF00817.15 KFH47018.1 - 1.6e-42 144.8 0.0 7.7e-42 142.6 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 KFH47018.1 - 6.8e-15 55.1 0.0 1.3e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KFH47018.1 - 0.034 14.1 0.0 0.086 12.9 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif Thaumatin PF00314.12 KFH47019.1 - 5.5e-70 235.1 3.2 8.6e-70 234.5 2.2 1.3 1 0 0 1 1 1 1 Thaumatin family CIA30 PF08547.7 KFH47020.1 - 4.7e-42 143.4 0.0 5.8e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) DUF1687 PF07955.6 KFH47021.1 - 1.1e-18 67.4 0.4 6.5e-18 64.9 0.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) ArsC PF03960.10 KFH47021.1 - 0.049 13.7 0.0 4.2 7.4 0.0 2.2 1 1 1 2 2 2 0 ArsC family DAO PF01266.19 KFH47022.1 - 4.3e-47 160.7 0.1 6.9e-47 160.0 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KFH47022.1 - 1.3e-07 31.5 0.2 0.0066 16.2 0.0 2.6 3 0 0 3 3 3 2 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KFH47022.1 - 4.4e-05 22.3 0.1 0.00082 18.1 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 KFH47022.1 - 4.9e-05 23.2 0.1 0.34 10.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFH47022.1 - 0.0012 18.9 0.0 0.016 15.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFH47022.1 - 0.0013 17.7 0.1 0.12 11.3 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KFH47022.1 - 0.0014 18.6 0.0 0.0043 17.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KFH47022.1 - 0.0023 16.8 0.0 0.0091 14.8 0.0 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Shikimate_DH PF01488.15 KFH47022.1 - 0.0055 16.8 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 KFH47022.1 - 0.064 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 ThiF family TFIIS_C PF01096.13 KFH47023.1 - 1.5e-19 69.3 2.4 1.5e-19 69.3 1.7 2.6 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KFH47023.1 - 2.2e-07 30.4 0.4 2.2e-07 30.4 0.3 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Desulfoferrod_N PF06397.7 KFH47023.1 - 0.00071 18.9 1.5 0.27 10.6 0.1 2.4 2 0 0 2 2 2 2 Desulfoferrodoxin, N-terminal domain Zn_Tnp_IS1595 PF12760.2 KFH47023.1 - 0.0049 16.6 5.2 0.11 12.2 0.2 2.5 2 1 0 2 2 2 2 Transposase zinc-ribbon domain Zn_ribbon_recom PF13408.1 KFH47023.1 - 0.0068 16.6 2.3 0.027 14.7 0.0 2.4 3 0 0 3 3 3 1 Recombinase zinc beta ribbon domain Elf1 PF05129.8 KFH47023.1 - 0.0075 15.9 1.8 0.34 10.6 0.1 2.3 2 0 0 2 2 2 1 Transcription elongation factor Elf1 like zf-Nse PF11789.3 KFH47023.1 - 0.05 13.1 0.9 0.1 12.1 0.0 2.0 2 1 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit Baculo_LEF5_C PF11792.3 KFH47023.1 - 0.065 12.6 0.1 0.22 10.9 0.0 2.0 1 1 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain DUF2387 PF09526.5 KFH47023.1 - 0.084 12.8 4.1 0.12 12.3 0.1 2.2 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) C1_1 PF00130.17 KFH47023.1 - 0.099 12.3 2.5 0.59 9.9 0.2 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.2 KFH47023.1 - 0.11 12.2 6.0 0.41 10.5 0.2 2.4 2 1 0 2 2 2 0 Double zinc ribbon IBR PF01485.16 KFH47023.1 - 0.27 11.1 7.3 5 7.0 0.2 3.0 2 1 0 2 2 2 0 IBR domain C1_4 PF07975.7 KFH47023.1 - 0.31 11.0 4.6 4.6 7.3 0.2 2.6 2 1 0 2 2 2 0 TFIIH C1-like domain zf-BED PF02892.10 KFH47023.1 - 0.72 9.6 5.9 1.5 8.6 0.1 3.2 3 1 1 4 4 4 0 BED zinc finger C1_3 PF07649.7 KFH47023.1 - 0.76 9.8 0.2 0.76 9.8 0.2 2.6 3 0 0 3 3 3 0 C1-like domain zf-HIT PF04438.11 KFH47023.1 - 4 7.1 5.8 4 7.1 0.1 3.1 4 0 0 4 4 4 0 HIT zinc finger OrfB_Zn_ribbon PF07282.6 KFH47023.1 - 6.6 6.4 6.6 9.7 5.9 0.6 2.5 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Nudix_N_2 PF14803.1 KFH47023.1 - 9.5 6.0 7.3 7.3 6.3 1.8 2.6 2 1 0 2 2 2 0 Nudix N-terminal Ribosomal_L14e PF01929.12 KFH47024.1 - 8.7e-23 80.4 3.9 1.2e-22 80.0 2.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 KFH47024.1 - 0.00085 18.9 1.6 0.0018 17.9 0.0 2.0 2 0 0 2 2 2 1 KOW motif Hexokinase_2 PF03727.11 KFH47025.1 - 5.3e-65 219.0 0.1 9.8e-65 218.1 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KFH47025.1 - 4.2e-62 209.1 0.0 6.7e-62 208.4 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Transgly PF00912.17 KFH47026.1 - 0.13 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Transglycosylase FA_desaturase PF00487.19 KFH47027.1 - 1.1e-25 90.5 24.5 1.8e-25 89.9 17.0 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KFH47027.1 - 2.7e-06 27.4 0.0 4.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) NdhL PF10716.4 KFH47027.1 - 0.011 15.5 0.1 0.03 14.0 0.1 1.7 1 0 0 1 1 1 0 NADH dehydrogenase transmembrane subunit UPF0547 PF10571.4 KFH47028.1 - 0.0044 16.6 1.3 0.0091 15.6 0.9 1.5 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 ISN1 PF06437.6 KFH47030.1 - 1.6e-179 596.9 0.0 1.8e-179 596.7 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Aminotran_3 PF00202.16 KFH47031.1 - 4.7e-08 32.2 0.0 6.5e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Pkinase PF00069.20 KFH47032.1 - 7.2e-12 45.0 0.0 5.8e-11 42.0 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain EthD PF07110.6 KFH47033.1 - 3.3e-21 75.9 1.0 4.2e-21 75.6 0.7 1.1 1 0 0 1 1 1 1 EthD domain Cut8_M PF14483.1 KFH47036.1 - 0.098 12.4 0.7 1.3 8.8 0.1 2.3 1 1 1 2 2 2 0 Cut8 dimerisation domain Sgf11 PF08209.6 KFH47037.1 - 2.2 7.6 8.0 0.2 10.9 2.2 1.7 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-C3HC4_3 PF13920.1 KFH47038.1 - 3.4e-08 33.0 5.2 6.3e-08 32.1 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFH47038.1 - 4.7e-08 32.9 9.5 4.7e-08 32.9 6.6 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFH47038.1 - 2.7e-06 27.1 7.0 2.7e-06 27.1 4.8 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KFH47038.1 - 3.5e-06 26.6 8.1 6.2e-06 25.8 5.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KFH47038.1 - 9.7e-06 25.1 8.7 1.9e-05 24.2 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFH47038.1 - 0.00046 19.8 3.0 0.0013 18.3 2.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFH47038.1 - 0.0022 17.8 7.4 0.0052 16.6 5.2 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Cript PF10235.4 KFH47038.1 - 0.0053 17.0 1.8 0.02 15.1 1.3 2.1 1 0 0 1 1 1 1 Microtubule-associated protein CRIPT zf-CCCH PF00642.19 KFH47038.1 - 0.028 14.1 2.8 0.071 12.8 1.9 1.8 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KFH47038.1 - 0.062 13.3 1.6 0.12 12.4 1.1 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type zf-Nse PF11789.3 KFH47038.1 - 0.35 10.4 2.4 0.65 9.5 1.7 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 KFH47038.1 - 0.4 10.5 2.5 0.88 9.3 1.7 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein L51_S25_CI-B8 PF05047.11 KFH47039.1 - 1.3e-14 53.6 0.0 1.7e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain ANTH PF07651.11 KFH47041.1 - 7.6e-79 264.3 0.0 7.6e-79 264.3 0.0 2.3 2 0 0 2 2 2 1 ANTH domain I_LWEQ PF01608.12 KFH47041.1 - 8.5e-65 217.3 8.8 8.5e-65 217.3 6.1 5.2 4 1 1 7 7 7 1 I/LWEQ domain ENTH PF01417.15 KFH47041.1 - 6.2e-05 22.8 0.2 0.00048 19.9 0.0 2.6 2 0 0 2 2 2 1 ENTH domain NFRKB_winged PF14465.1 KFH47041.1 - 0.065 13.0 1.1 1.3 8.8 0.2 3.1 3 0 0 3 3 3 0 NFRKB Winged Helix-like SapB_1 PF05184.10 KFH47041.1 - 9.4 6.1 6.5 8.6 6.3 0.1 3.1 3 0 0 3 3 3 0 Saposin-like type B, region 1 UPF0016 PF01169.14 KFH47043.1 - 2.5e-42 142.8 25.0 1.1e-22 79.9 5.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 ADH_zinc_N PF00107.21 KFH47044.1 - 1.2e-25 89.5 0.0 1.9e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFH47044.1 - 1.8e-20 72.7 0.8 2.9e-20 72.0 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KFH47044.1 - 5.4e-08 33.7 0.0 7.9e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF849 PF05853.7 KFH47044.1 - 0.0067 15.3 0.0 0.0095 14.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic protein of unknown function (DUF849) 2-Hacid_dh_C PF02826.14 KFH47044.1 - 0.023 13.8 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KFH47045.1 - 6.5e-41 139.4 0.0 3e-27 94.8 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KFH47045.1 - 0.067 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 NADH(P)-binding Ank_2 PF12796.2 KFH47046.1 - 9.2e-110 359.2 7.8 9e-24 83.6 0.1 7.3 1 1 6 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 KFH47046.1 - 2.6e-101 326.7 25.5 2.9e-09 36.2 0.1 15.1 15 0 0 15 15 15 14 Ankyrin repeat Ank_4 PF13637.1 KFH47046.1 - 2.8e-74 244.2 8.5 4.8e-11 42.8 0.0 10.5 5 2 6 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFH47046.1 - 4.4e-72 230.7 7.1 1.4e-05 24.8 0.0 15.1 15 0 0 15 15 15 13 Ankyrin repeat Ank_5 PF13857.1 KFH47046.1 - 1.9e-66 218.6 27.0 4.2e-11 42.7 0.3 13.8 2 2 13 15 15 15 14 Ankyrin repeats (many copies) DHHA1 PF02272.14 KFH47046.1 - 0.065 12.9 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 DHHA1 domain DNA_pol_B PF00136.16 KFH47048.1 - 8.1e-96 321.6 0.0 1.2e-95 321.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KFH47048.1 - 3.9e-25 88.4 0.0 2.2e-14 53.0 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KFH47048.1 - 2.4e-18 65.8 3.6 2.4e-18 65.8 2.5 1.9 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta zf-FPG_IleRS PF06827.9 KFH47048.1 - 1 9.0 6.9 0.4 10.3 2.4 2.2 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS UBX PF00789.15 KFH47049.1 - 2.3e-13 49.9 0.0 4.5e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 UBX domain CDC27 PF09507.5 KFH47049.1 - 0.044 13.0 20.8 0.057 12.6 14.4 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CAF-1_p150 PF11600.3 KFH47049.1 - 0.078 12.3 27.5 0.14 11.5 19.0 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Neur_chan_memb PF02932.11 KFH47049.1 - 2.8 7.7 5.3 4.5 7.0 3.6 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Asp-B-Hydro_N PF05279.6 KFH47049.1 - 4.5 7.0 16.8 7 6.4 11.6 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Med19 PF10278.4 KFH47049.1 - 4.5 6.9 17.4 8.5 6.0 12.1 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 CAF-1_p150 PF11600.3 KFH47050.1 - 0.00061 19.2 2.1 0.00074 18.9 1.4 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal ACPS PF01648.15 KFH47051.1 - 2e-08 34.0 0.0 4e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ribosomal_S4 PF00163.14 KFH47053.1 - 3.6e-28 97.7 0.8 6.8e-28 96.8 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 KFH47053.1 - 4.3e-13 48.4 1.2 4.3e-13 48.4 0.8 2.5 3 0 0 3 3 3 1 S4 domain Sas10_Utp3 PF04000.10 KFH47054.1 - 4.2e-16 58.8 1.6 4.2e-16 58.8 1.1 2.1 2 1 0 2 2 2 1 Sas10/Utp3/C1D family UPF0184 PF03670.8 KFH47054.1 - 0.04 14.0 0.5 0.04 14.0 0.4 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) Med19 PF10278.4 KFH47054.1 - 0.075 12.7 13.8 0.1 12.2 9.6 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 UPF0172 PF03665.8 KFH47054.1 - 0.2 11.1 4.7 0.31 10.5 3.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) NPV_P10 PF05531.7 KFH47054.1 - 0.3 11.3 3.1 0.34 11.1 0.3 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4604 PF15377.1 KFH47054.1 - 0.45 10.7 20.6 0.57 10.3 14.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) DUF1675 PF07897.6 KFH47054.1 - 0.79 9.5 10.4 0.92 9.3 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) IncA PF04156.9 KFH47054.1 - 1.6 8.3 7.8 1.9 8.0 3.3 2.4 1 1 0 1 1 1 0 IncA protein TSA PF03249.8 KFH47054.1 - 3.4 6.0 10.0 4.5 5.7 6.9 1.2 1 0 0 1 1 1 0 Type specific antigen UQ_con PF00179.21 KFH47056.1 - 2.4e-47 159.9 0.0 2.8e-47 159.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFH47056.1 - 0.00054 19.7 0.0 0.00068 19.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KFH47056.1 - 0.0042 16.7 0.1 0.0078 15.8 0.0 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 KFH47056.1 - 0.014 15.2 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 RWD domain PI-PLC-X PF00388.14 KFH47057.1 - 3.3e-56 188.7 0.0 6e-56 187.9 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KFH47057.1 - 3.4e-36 123.7 0.0 5.9e-36 123.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KFH47057.1 - 0.04 13.9 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like SURF1 PF02104.10 KFH47058.1 - 5.1e-68 229.0 0.0 6.5e-68 228.7 0.0 1.1 1 0 0 1 1 1 1 SURF1 family dsDNA_bind PF01984.15 KFH47060.1 - 2.9e-34 117.2 10.4 3.7e-34 116.9 7.2 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4615 PF15393.1 KFH47060.1 - 0.026 14.7 2.4 0.052 13.7 1.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4615) ATP-sulfurylase PF01747.12 KFH47061.1 - 1.5e-87 292.4 0.1 2.1e-87 291.9 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 KFH47061.1 - 2e-56 189.9 0.0 3.1e-56 189.3 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 KFH47061.1 - 3.9e-54 182.3 0.0 7.2e-54 181.5 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain KTI12 PF08433.5 KFH47061.1 - 0.0011 18.2 0.0 0.0017 17.6 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 KFH47061.1 - 0.006 16.4 0.2 0.013 15.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain Mpv17_PMP22 PF04117.7 KFH47063.1 - 1.1e-09 37.7 3.6 1.2e-08 34.4 0.1 2.6 2 0 0 2 2 2 2 Mpv17 / PMP22 family RRM_6 PF14259.1 KFH47064.1 - 9.1e-06 25.5 0.0 1.6e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFH47064.1 - 0.001 18.6 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH47064.1 - 0.002 17.9 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_43 PF04616.9 KFH47065.1 - 4.1e-17 62.1 13.3 4.7e-08 32.4 2.2 4.0 3 1 0 3 3 3 3 Glycosyl hydrolases family 43 Metallophos_2 PF12850.2 KFH47066.1 - 8.5e-13 48.4 0.0 1.3e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KFH47066.1 - 2.7e-08 33.4 3.0 1.6e-06 27.7 2.1 2.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase EOS1 PF12326.3 KFH47067.1 - 3.8e-25 88.2 6.3 8.7e-22 77.3 1.0 2.2 1 1 1 2 2 2 2 N-glycosylation protein PEPcase PF00311.12 KFH47067.1 - 0.36 8.6 2.9 0.69 7.6 0.0 2.0 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxylase PAM2 PF07145.10 KFH47068.1 - 0.001 18.4 12.9 0.12 11.9 1.8 3.8 3 0 0 3 3 3 2 Ataxin-2 C-terminal region DUF2404 PF10296.4 KFH47069.1 - 2e-29 101.5 0.0 4.6e-29 100.3 0.0 1.7 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) Dabb PF07876.7 KFH47070.1 - 1.9e-08 34.6 0.0 2.1e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Fungal_trans PF04082.13 KFH47071.1 - 2.5e-07 29.8 0.2 4.3e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3154 PF11351.3 KFH47071.1 - 0.074 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) HMG_box PF00505.14 KFH47072.1 - 1.4e-17 63.6 2.9 2.2e-17 63.0 2.0 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFH47072.1 - 4.9e-06 26.8 1.1 1e-05 25.7 0.8 1.5 1 0 0 1 1 1 1 HMG-box domain CcmH PF03918.9 KFH47074.1 - 0.093 11.7 0.0 0.095 11.6 0.0 1.1 1 0 0 1 1 1 0 Cytochrome C biogenesis protein YIF1 PF03878.10 KFH47075.1 - 7.5e-77 257.7 2.4 9e-77 257.4 1.7 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 KFH47075.1 - 1.6 8.2 12.8 0.79 9.2 7.1 1.7 1 1 1 2 2 2 0 Yip1 domain CENP-T PF15511.1 KFH47076.1 - 1.1e-85 288.4 26.9 1.1e-85 288.4 18.6 2.0 3 0 0 3 3 3 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 KFH47076.1 - 5.7e-08 32.8 0.0 1.2e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 KFH47076.1 - 1.3e-06 28.4 0.0 2.9e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFH47076.1 - 0.00041 20.3 0.0 0.00072 19.5 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KFH47076.1 - 0.012 15.3 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated ADC PF06314.6 KFH47077.1 - 0.00057 19.2 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) DUF1860 PF08949.5 KFH47077.1 - 3.5 7.1 6.5 0.63 9.5 1.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1860) HSP70 PF00012.15 KFH47078.1 - 6.9e-11 40.7 0.3 2.8e-09 35.4 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 KFH47078.1 - 0.0056 15.3 0.2 0.034 12.7 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein zf-SAP30 PF13866.1 KFH47078.1 - 0.017 14.7 0.1 0.037 13.6 0.1 1.5 1 0 0 1 1 1 0 SAP30 zinc-finger Pkinase PF00069.20 KFH47079.1 - 1.7e-64 217.5 0.0 2.8e-64 216.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH47079.1 - 1.4e-31 109.4 0.0 3e-31 108.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.2 KFH47079.1 - 2e-27 95.3 0.3 2e-15 56.8 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFH47079.1 - 3.2e-23 80.3 0.5 3e-06 26.7 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 KFH47079.1 - 1.3e-18 66.9 0.1 1.9e-09 37.7 0.1 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFH47079.1 - 6.1e-17 60.0 0.5 0.001 19.0 0.0 5.4 5 0 0 5 5 4 3 Ankyrin repeat Ank_5 PF13857.1 KFH47079.1 - 9.3e-16 57.5 0.9 1.6e-06 28.1 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) AAA_16 PF13191.1 KFH47079.1 - 1.1e-08 35.3 0.5 1.1e-08 35.3 0.3 3.6 3 1 1 4 4 4 1 AAA ATPase domain NACHT PF05729.7 KFH47079.1 - 7.2e-07 29.0 0.3 2.2e-06 27.4 0.2 1.9 1 0 0 1 1 1 1 NACHT domain Kinase-like PF14531.1 KFH47079.1 - 1.7e-06 27.2 0.2 8.1e-06 24.9 0.0 2.2 3 0 0 3 3 3 1 Kinase-like AAA_22 PF13401.1 KFH47079.1 - 1.1e-05 25.6 0.0 3.2e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KFH47079.1 - 0.0015 17.4 0.0 0.0041 16.0 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.1 KFH47079.1 - 0.068 13.0 0.7 0.33 10.8 0.1 2.5 2 1 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 KFH47079.1 - 0.093 11.7 1.8 1.3 7.9 0.1 2.7 2 1 1 3 3 3 0 KAP family P-loop domain Pox_ser-thr_kin PF05445.6 KFH47079.1 - 0.23 10.2 0.0 0.37 9.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Tim44 PF04280.10 KFH47080.1 - 1.1e-10 41.7 4.3 2.1e-10 40.7 1.2 2.4 2 1 0 2 2 2 1 Tim44-like domain MBA1 PF07961.6 KFH47080.1 - 0.0041 15.9 0.0 0.0058 15.4 0.0 1.2 1 0 0 1 1 1 1 MBA1-like protein Mt_ATP-synt_D PF05873.7 KFH47081.1 - 1.3e-17 63.8 0.9 1.6e-17 63.6 0.6 1.2 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) T5orf172 PF10544.4 KFH47081.1 - 0.0033 17.7 0.4 0.098 13.0 0.3 2.2 1 1 0 1 1 1 1 T5orf172 domain Blt1 PF12754.2 KFH47081.1 - 0.017 14.7 0.4 0.023 14.2 0.3 1.1 1 0 0 1 1 1 0 Cell-cycle control medial ring component MUG113 PF13455.1 KFH47081.1 - 0.045 14.1 0.1 0.57 10.6 0.1 2.1 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 Dor1 PF04124.7 KFH47081.1 - 0.17 10.3 2.3 0.21 10.0 1.4 1.3 1 1 0 1 1 1 0 Dor1-like family PAT1 PF09770.4 KFH47082.1 - 9.4 4.3 20.4 11 4.0 14.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ank PF00023.25 KFH47083.1 - 1.6e-11 43.4 0.0 0.0069 16.1 0.0 3.7 3 1 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 KFH47083.1 - 5.3e-11 42.7 0.0 1.4e-10 41.4 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFH47083.1 - 7.6e-10 39.0 0.6 6.4e-05 23.3 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFH47083.1 - 3.1e-09 36.7 0.1 0.077 13.2 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFH47083.1 - 3.6e-09 35.9 0.0 0.076 13.3 0.0 3.6 3 1 0 3 3 3 3 Ankyrin repeat DUF3447 PF11929.3 KFH47083.1 - 0.05 13.3 0.0 4.5 7.1 0.0 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF3447) Actino_peptide PF14408.1 KFH47083.1 - 0.074 12.9 0.3 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 Ribosomally synthesized peptide in actinomycetes Apc5 PF12862.2 KFH47084.1 - 6.6e-33 112.4 3.4 6.6e-33 112.4 2.3 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_16 PF13432.1 KFH47084.1 - 0.0045 17.6 6.3 4.4 8.1 0.2 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.4 KFH47084.1 - 0.082 12.8 7.6 0.41 10.5 0.1 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 KFH47084.1 - 0.34 11.0 6.1 6.8 6.8 0.0 3.6 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFH47084.1 - 0.64 10.3 12.5 5.6 7.3 0.3 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFH47084.1 - 2 8.5 4.9 3.9 7.6 0.4 3.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Ring_hydroxyl_A PF00848.14 KFH47085.1 - 5.8e-39 133.9 3.3 1.3e-38 132.7 2.3 1.6 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 KFH47085.1 - 4e-15 55.1 0.0 7e-15 54.3 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Acetyltransf_1 PF00583.19 KFH47086.1 - 0.00013 21.9 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFH47086.1 - 0.02 15.0 0.0 0.031 14.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GBS_Bsp-like PF08481.5 KFH47086.1 - 0.056 13.3 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 GBS Bsp-like repeat MAT_Alpha1 PF04769.7 KFH47087.1 - 4.5e-51 173.0 0.0 6.4e-51 172.5 0.0 1.1 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 IBN_N PF03810.14 KFH47088.1 - 7.7e-15 54.5 2.1 3.8e-13 49.1 0.1 3.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.5 KFH47088.1 - 1.8e-08 33.3 0.1 2.3e-07 29.7 0.0 2.4 2 1 0 2 2 2 1 Cse1 Xpo1 PF08389.7 KFH47088.1 - 2.7e-05 24.1 5.5 0.00025 21.0 0.1 4.1 4 0 0 4 4 4 1 Exportin 1-like protein DUF2435 PF10363.4 KFH47088.1 - 0.0091 15.8 0.1 0.032 14.1 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2435) HET PF06985.6 KFH47090.1 - 3e-12 46.8 0.0 4.6e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aminotran_3 PF00202.16 KFH47091.1 - 6.5e-40 137.0 0.0 6.9e-23 81.0 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-III GRAM PF02893.15 KFH47093.1 - 1.8e-16 59.4 0.0 3e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 GRAM domain NUDIX PF00293.23 KFH47095.1 - 3.6e-11 42.8 0.0 5.3e-10 39.0 0.0 2.4 1 1 0 1 1 1 1 NUDIX domain RFamide_26RFa PF11109.3 KFH47095.1 - 0.012 15.5 0.7 0.2 11.5 0.0 2.7 2 1 0 2 2 2 0 Orexigenic neuropeptide Qrfp/P518 Fungal_trans PF04082.13 KFH47096.1 - 1.3e-22 79.9 0.3 1.3e-22 79.9 0.2 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH47096.1 - 1e-10 41.3 8.5 1.8e-10 40.5 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.7 KFH47097.1 - 4.5e-26 90.7 2.4 1.2e-25 89.4 1.7 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFH47097.1 - 2.6e-16 59.3 0.3 3.3e-15 55.7 0.2 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 KFH47097.1 - 0.0098 15.2 0.1 0.021 14.2 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.15 KFH47097.1 - 0.02 15.0 0.0 0.044 13.8 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 KFH47097.1 - 0.021 14.8 0.2 0.12 12.4 0.2 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain ThiF PF00899.16 KFH47097.1 - 0.041 13.6 0.5 0.081 12.7 0.3 1.4 1 0 0 1 1 1 0 ThiF family TrkA_N PF02254.13 KFH47097.1 - 0.05 13.6 0.0 0.086 12.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 KFH47097.1 - 0.052 13.2 0.5 0.086 12.4 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 KFH47097.1 - 0.056 13.4 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AdoHcyase_NAD PF00670.16 KFH47097.1 - 0.12 12.2 0.2 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NADH_4Fe-4S PF10589.4 KFH47097.1 - 0.3 10.2 2.6 0.68 9.1 1.8 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region DUF2418 PF10332.4 KFH47098.1 - 3.3e-35 120.3 0.2 5.6e-35 119.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) PALP PF00291.20 KFH47099.1 - 5.7e-72 242.5 0.3 7.7e-72 242.1 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 KFH47099.1 - 2.5e-36 123.1 0.0 5.4e-20 70.7 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Wound_ind PF08186.6 KFH47099.1 - 0.14 12.1 0.1 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 Wound-inducible basic protein family Syndecan PF01034.15 KFH47100.1 - 0.13 11.9 1.1 0.35 10.5 0.8 1.7 1 0 0 1 1 1 0 Syndecan domain BCIP PF13862.1 KFH47101.1 - 2.5e-64 216.3 0.1 3.1e-64 216.0 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein E1-E2_ATPase PF00122.15 KFH47102.1 - 4.8e-62 209.0 1.1 4.8e-62 209.0 0.7 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KFH47102.1 - 8.3e-30 104.8 0.0 1.2e-28 101.0 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 KFH47102.1 - 5.4e-24 84.7 8.7 5.4e-24 84.7 6.1 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.21 KFH47102.1 - 4.3e-16 58.1 0.0 1.3e-15 56.5 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KFH47102.1 - 2.2e-15 56.3 0.0 8.6e-15 54.4 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KFH47102.1 - 1.2e-12 48.3 0.0 2.6e-12 47.3 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFH47102.1 - 0.0055 16.3 0.4 0.011 15.3 0.2 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Glyco_hydro_76 PF03663.9 KFH47103.1 - 1.2e-17 64.3 0.1 3.2e-15 56.4 0.0 3.5 2 1 0 2 2 2 1 Glycosyl hydrolase family 76 Cyclin_N PF00134.18 KFH47104.1 - 1.4e-05 24.6 0.0 0.00021 20.8 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain DUF1191 PF06697.7 KFH47105.1 - 0.001 17.9 0.0 0.0012 17.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Herpes_gE PF02480.11 KFH47105.1 - 0.0083 14.4 0.0 0.0092 14.2 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF456 PF04306.8 KFH47105.1 - 0.02 14.9 0.0 0.027 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF456) TMEM51 PF15345.1 KFH47105.1 - 0.033 13.8 0.0 0.042 13.5 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 PIRT PF15099.1 KFH47105.1 - 0.041 13.1 1.0 0.059 12.5 0.4 1.5 1 1 1 2 2 2 0 Phosphoinositide-interacting protein family DUF1049 PF06305.6 KFH47105.1 - 0.049 13.1 0.3 0.071 12.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Syndecan PF01034.15 KFH47105.1 - 0.075 12.6 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain Gypsy PF07253.6 KFH47105.1 - 0.1 10.8 0.0 0.1 10.8 0.0 1.0 1 0 0 1 1 1 0 Gypsy protein Fungal_trans PF04082.13 KFH47106.1 - 7.9e-21 74.0 0.0 1.6e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH47106.1 - 3.2e-08 33.3 11.8 5.3e-08 32.6 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.4 KFH47106.1 - 0.17 10.1 23.8 0.25 9.5 16.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2413 PF10310.4 KFH47107.1 - 2.3e-139 465.0 0.3 2.9e-139 464.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) DUF461 PF04314.8 KFH47107.1 - 0.068 12.8 0.2 0.068 12.8 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF461) CPSase_L_D2 PF02786.12 KFH47108.1 - 4.1e-113 375.8 0.2 7.1e-84 280.3 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 KFH47108.1 - 1.7e-45 153.6 0.0 3.8e-45 152.5 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 KFH47108.1 - 1.3e-42 145.4 0.1 4.6e-42 143.6 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 KFH47108.1 - 7.1e-42 142.4 0.0 1.5e-41 141.4 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_chain PF00289.17 KFH47108.1 - 4.2e-41 139.5 0.0 2.2e-20 72.7 0.0 2.9 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 KFH47108.1 - 8e-41 138.6 0.0 2.5e-40 137.0 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 KFH47108.1 - 3.3e-37 127.9 0.1 1.1e-23 83.9 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain OTCace PF00185.19 KFH47108.1 - 1.7e-26 92.9 0.0 8e-26 90.7 0.0 2.2 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATPgrasp_Ter PF15632.1 KFH47108.1 - 1.8e-23 82.8 0.1 1.3e-12 47.0 0.0 3.9 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 KFH47108.1 - 1.1e-20 73.2 0.0 7.3e-20 70.7 0.0 2.5 2 0 0 2 2 2 1 MGS-like domain ATP-grasp PF02222.17 KFH47108.1 - 2.8e-17 62.5 0.1 2.1e-08 33.6 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KFH47108.1 - 3e-17 62.6 0.6 1.2e-08 34.6 0.1 2.7 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 KFH47108.1 - 1.8e-06 27.8 0.5 0.026 14.3 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 KFH47108.1 - 8.3e-05 22.2 0.1 0.36 10.3 0.0 3.3 3 1 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Peptidase_C26 PF07722.8 KFH47108.1 - 0.0018 17.7 0.2 0.051 13.0 0.1 2.6 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 KFH47108.1 - 0.0074 15.7 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family Glyco_hydro_92 PF07971.7 KFH47110.1 - 2.1e-143 478.6 0.0 2.7e-143 478.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 DUF3622 PF12286.3 KFH47110.1 - 0.032 14.5 0.2 0.064 13.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3622) Endonuclease_5 PF04493.9 KFH47110.1 - 0.11 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Endonuclease V IBR PF01485.16 KFH47111.1 - 4.8e-07 29.5 4.1 4.8e-07 29.5 2.9 4.3 5 0 0 5 5 5 2 IBR domain DUF411 PF04214.8 KFH47111.1 - 0.11 12.0 0.1 0.39 10.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF Baculo_IE-1 PF05290.6 KFH47111.1 - 2.3 7.9 11.2 79 2.9 7.6 2.8 2 1 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Pkinase PF00069.20 KFH47112.1 - 1.9e-71 240.2 0.0 2.4e-71 239.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH47112.1 - 8.9e-31 106.8 0.0 1.2e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFH47112.1 - 1.3e-05 24.3 0.1 8.2e-05 21.7 0.0 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFH47112.1 - 0.00027 20.7 0.1 0.0012 18.6 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KFH47112.1 - 0.00038 19.5 0.0 0.019 13.9 0.0 2.2 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 KFH47112.1 - 0.023 14.0 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family CDC45 PF02724.9 KFH47113.1 - 4.4e-235 781.4 0.2 5.8e-234 777.7 0.1 2.8 1 1 0 1 1 1 1 CDC45-like protein Cwf_Cwc_15 PF04889.7 KFH47113.1 - 0.0018 18.0 8.1 0.0018 18.0 5.6 2.5 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein Phage_fiber PF03335.8 KFH47113.1 - 0.57 10.0 3.4 20 5.3 0.4 2.8 2 0 0 2 2 2 0 Phage tail fibre repeat DUF4581 PF15167.1 KFH47113.1 - 0.63 9.9 4.0 1.9 8.3 2.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4581) DUF572 PF04502.8 KFH47113.1 - 0.83 8.8 17.7 1.4 8.1 7.4 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) FAM60A PF15396.1 KFH47113.1 - 2.5 7.8 7.2 0.19 11.4 0.8 1.9 2 0 0 2 2 2 0 Protein Family FAM60A MU117 PF15474.1 KFH47114.1 - 5.6e-10 39.5 0.5 8.3e-10 39.0 0.4 1.3 1 0 0 1 1 1 1 Meiotically up-regulated gene family FAR1 PF03101.10 KFH47115.1 - 4.6e-05 23.8 0.0 0.00011 22.6 0.0 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain DUF4618 PF15397.1 KFH47115.1 - 0.0017 17.7 3.2 0.003 16.9 2.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) DUF2408 PF10303.4 KFH47115.1 - 0.035 14.2 0.2 0.08 13.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF4200 PF13863.1 KFH47115.1 - 0.082 12.8 8.6 0.17 11.8 6.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Med9 PF07544.8 KFH47115.1 - 0.26 11.0 6.1 0.72 9.6 4.2 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Spc7 PF08317.6 KFH47115.1 - 0.58 8.7 7.2 0.71 8.4 4.4 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF1342 PF07072.6 KFH47115.1 - 0.66 9.6 3.9 0.48 10.0 1.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1342) AAA_17 PF13207.1 KFH47116.1 - 5.3e-06 27.2 0.4 2.9e-05 24.8 0.3 2.1 1 1 0 1 1 1 1 AAA domain ArgK PF03308.11 KFH47116.1 - 3.7e-05 22.6 0.0 5.4e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 ArgK protein SRP54 PF00448.17 KFH47116.1 - 0.00013 21.4 0.0 0.00019 20.9 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain KAP_NTPase PF07693.9 KFH47116.1 - 0.00016 20.7 0.0 0.00024 20.2 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain PRK PF00485.13 KFH47116.1 - 0.00026 20.5 0.0 0.00038 20.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.1 KFH47116.1 - 0.00048 20.1 0.0 0.0013 18.7 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 KFH47116.1 - 0.00064 18.8 0.0 0.0012 17.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 KFH47116.1 - 0.00087 19.6 0.0 0.0022 18.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.1 KFH47116.1 - 0.002 17.7 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KFH47116.1 - 0.0021 17.4 0.0 0.004 16.5 0.0 1.4 1 0 0 1 1 1 1 Thymidylate kinase UPF0079 PF02367.12 KFH47116.1 - 0.0037 16.8 0.0 0.0072 15.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 KFH47116.1 - 0.011 15.6 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KFH47116.1 - 0.016 14.8 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain APS_kinase PF01583.15 KFH47116.1 - 0.017 14.8 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase NTPase_1 PF03266.10 KFH47116.1 - 0.018 14.7 0.1 0.032 13.9 0.1 1.3 1 0 0 1 1 1 0 NTPase AAA PF00004.24 KFH47116.1 - 0.021 15.0 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 KFH47116.1 - 0.026 13.9 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 KFH47116.1 - 0.027 13.3 0.0 0.04 12.7 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.1 KFH47116.1 - 0.034 13.8 0.2 0.089 12.5 0.1 1.8 2 0 0 2 2 2 0 Part of AAA domain ABC_tran PF00005.22 KFH47116.1 - 0.037 14.3 0.0 0.059 13.6 0.0 1.3 1 0 0 1 1 1 0 ABC transporter CbiA PF01656.18 KFH47116.1 - 0.041 13.2 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_14 PF13173.1 KFH47116.1 - 0.071 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KFH47116.1 - 0.078 12.9 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 KFH47116.1 - 0.08 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 KFH47116.1 - 0.085 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 KFH47116.1 - 0.093 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein LpxK PF02606.9 KFH47116.1 - 0.1 11.5 0.1 0.17 10.7 0.1 1.3 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase AAA_23 PF13476.1 KFH47116.1 - 0.14 12.4 0.1 0.2 11.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.15 KFH47117.1 - 3.5e-124 414.4 0.7 4.3e-124 414.1 0.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFH47117.1 - 9.9e-16 57.4 0.4 4.5e-10 39.0 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFH47117.1 - 0.0002 20.5 0.1 0.15 11.1 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 KFH47117.1 - 0.0017 18.8 0.1 1.1 9.8 0.0 2.8 3 0 0 3 3 3 2 Miro-like protein AAA_29 PF13555.1 KFH47117.1 - 0.05 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Phage_GPL PF05926.6 KFH47118.1 - 0.072 12.9 0.0 0.083 12.7 0.0 1.2 1 0 0 1 1 1 0 Phage head completion protein (GPL) PMSR PF01625.16 KFH47119.1 - 1.1e-58 197.4 0.0 1.4e-58 197.2 0.0 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DUF1774 PF08611.5 KFH47120.1 - 1.9e-34 117.6 3.6 1.9e-34 117.6 2.5 2.7 3 1 1 4 4 4 1 Fungal protein of unknown function (DUF1774) Avl9 PF09794.4 KFH47121.1 - 3.7e-142 473.3 0.0 4.7e-142 472.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 KFH47121.1 - 4.5e-07 29.5 0.1 0.00027 20.5 0.0 2.4 1 1 1 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.4 KFH47121.1 - 4.6e-06 26.1 0.1 0.00014 21.2 0.1 2.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Solute_trans_a PF03619.11 KFH47122.1 - 1.5e-105 352.4 8.1 1.8e-105 352.1 5.6 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF373 PF04123.8 KFH47122.1 - 5.1 6.0 7.7 0.56 9.1 2.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF373) adh_short PF00106.20 KFH47124.1 - 1.3e-15 57.6 0.1 2.2e-15 56.9 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH47124.1 - 2.5e-08 33.7 0.1 4.8e-08 32.8 0.1 1.5 1 1 0 1 1 1 1 KR domain AraC_binding_2 PF14525.1 KFH47124.1 - 0.009 15.5 0.1 0.013 15.0 0.1 1.1 1 0 0 1 1 1 1 AraC-binding-like domain D-aminoacyl_C PF07908.7 KFH47124.1 - 0.1 11.9 0.0 0.41 9.9 0.0 2.1 2 0 0 2 2 2 0 D-aminoacylase, C-terminal region Sec5 PF15469.1 KFH47126.1 - 4.6e-35 120.9 0.1 1.5e-33 116.0 0.0 2.7 3 0 0 3 3 3 1 Exocyst complex component Sec5 Vps51 PF08700.6 KFH47126.1 - 2.1e-05 24.2 0.3 0.00011 21.9 0.0 2.5 2 0 0 2 2 2 1 Vps51/Vps67 Oxidored_FMN PF00724.15 KFH47127.1 - 2e-53 181.6 0.0 2.4e-53 181.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family MTHFR PF02219.12 KFH47127.1 - 0.016 14.2 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Methylenetetrahydrofolate reductase DUF2267 PF10025.4 KFH47127.1 - 0.034 14.2 0.1 0.093 12.7 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) NMO PF03060.10 KFH47127.1 - 0.29 10.2 1.9 2.9 6.9 0.1 2.7 2 1 1 3 3 3 0 Nitronate monooxygenase zf-DHHC PF01529.15 KFH47128.1 - 0.055 12.8 0.1 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase MgtE PF01769.11 KFH47128.1 - 0.056 13.7 0.5 1 9.6 0.2 2.1 2 0 0 2 2 2 0 Divalent cation transporter ATP-synt_F PF01990.12 KFH47129.1 - 2.3e-27 95.1 0.9 2e-26 92.2 0.6 1.9 1 1 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Transglut_core PF01841.14 KFH47130.1 - 2.2e-09 37.5 0.0 4.8e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Gp_dh_C PF02800.15 KFH47131.1 - 1.3e-75 252.1 0.0 1.8e-75 251.6 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KFH47131.1 - 4.8e-60 201.9 0.1 9.5e-60 200.9 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 KFH47131.1 - 0.00072 19.4 0.1 0.0052 16.6 0.0 2.3 3 0 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 KFH47131.1 - 0.056 12.5 0.1 0.14 11.2 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AhpC-TSA_2 PF13911.1 KFH47132.1 - 1.6e-11 44.1 0.1 2.5e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme PHD PF00628.24 KFH47133.1 - 1.2e-08 34.4 8.9 2.6e-08 33.4 6.2 1.6 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 KFH47133.1 - 1.3e-06 28.7 0.2 5.4e-05 23.5 0.0 2.9 2 0 0 2 2 2 1 SET domain Mito_carr PF00153.22 KFH47134.1 - 6e-58 192.5 4.9 8.8e-20 70.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Glycos_transf_4 PF00953.16 KFH47135.1 - 2.1e-27 95.8 8.8 2.1e-27 95.8 6.1 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 4 SNARE_assoc PF09335.6 KFH47135.1 - 1.6 8.9 9.5 0.45 10.7 0.5 3.1 3 0 0 3 3 3 0 SNARE associated Golgi protein p450 PF00067.17 KFH47136.1 - 1.3e-75 254.7 0.0 1.5e-75 254.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AFG1_ATPase PF03969.11 KFH47137.1 - 1.1e-94 317.2 0.0 1.1e-89 300.8 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 KFH47137.1 - 4.7e-05 23.4 0.1 0.03 14.3 0.0 2.7 1 1 0 2 2 2 2 AAA ATPase domain Sigma54_activ_2 PF14532.1 KFH47137.1 - 0.00028 20.9 0.0 0.0046 16.9 0.0 2.8 3 1 0 3 3 3 1 Sigma-54 interaction domain Bac_DnaA PF00308.13 KFH47137.1 - 0.0038 16.9 0.0 0.7 9.5 0.0 2.6 2 1 0 2 2 2 1 Bacterial dnaA protein AAA_22 PF13401.1 KFH47137.1 - 0.0072 16.4 0.0 0.05 13.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KFH47137.1 - 0.028 14.1 0.0 0.061 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 KFH47137.1 - 0.089 12.9 0.0 0.26 11.4 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Glyco_trans_1_4 PF13692.1 KFH47138.1 - 3.4e-22 79.0 0.0 1.3e-19 70.6 0.0 2.5 2 1 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KFH47138.1 - 0.00019 21.6 0.0 0.00052 20.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain WHG PF13305.1 KFH47138.1 - 0.062 13.8 0.1 1.2 9.7 0.0 2.3 2 0 0 2 2 2 0 WHG domain Malic_M PF03949.10 KFH47139.1 - 2.7e-77 259.7 0.0 3.6e-77 259.3 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KFH47139.1 - 8.8e-66 220.9 0.0 1.3e-65 220.3 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain TFIIIC_delta PF12657.2 KFH47140.1 - 5.4e-22 78.3 0.0 9.8e-21 74.2 0.0 2.2 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 KFH47140.1 - 1.2e-08 34.7 1.1 2.3e-08 33.8 0.7 1.4 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex Pyridox_oxidase PF01243.15 KFH47141.1 - 2.2e-08 34.0 0.0 3.9e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase MMPL PF03176.10 KFH47141.1 - 0.091 11.4 0.1 0.16 10.6 0.0 1.4 1 1 0 1 1 1 0 MMPL family NUFIP1 PF10453.4 KFH47141.1 - 0.15 11.5 0.8 0.26 10.8 0.1 1.7 2 0 0 2 2 2 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Metallophos PF00149.23 KFH47143.1 - 1.4e-35 122.4 0.6 8.3e-29 100.4 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase zf-C2H2_jaz PF12171.3 KFH47144.1 - 9.1e-08 32.0 0.2 2.1e-07 30.9 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFH47144.1 - 2.8e-05 24.1 0.4 6.2e-05 23.0 0.3 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF1777 PF08648.7 KFH47144.1 - 0.00074 19.2 11.7 0.00074 19.2 8.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) zf-DBF PF07535.7 KFH47144.1 - 0.005 16.4 0.1 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 DBF zinc finger CAF-1_p150 PF11600.3 KFH47144.1 - 9.7 5.4 30.3 4.4 6.6 13.1 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Fungal_trans PF04082.13 KFH47145.1 - 6.7e-19 67.7 0.0 1.2e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH47145.1 - 5.9e-09 35.6 9.9 1e-08 34.9 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-RING_2 PF13639.1 KFH47146.1 - 9.9e-08 31.6 6.8 1.1e-06 28.3 3.5 2.8 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFH47146.1 - 8.1e-07 28.6 1.3 8.1e-07 28.6 0.9 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFH47146.1 - 0.00011 22.2 1.7 0.00022 21.2 1.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KFH47146.1 - 0.00013 21.6 2.6 0.00013 21.6 1.8 2.1 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFH47146.1 - 0.00014 21.7 9.6 0.00063 19.7 4.0 3.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFH47146.1 - 0.00017 21.1 4.8 0.00019 20.9 1.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 KFH47146.1 - 0.0033 16.9 3.8 0.0033 16.9 2.6 2.0 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 KFH47146.1 - 0.013 15.2 4.2 0.065 12.9 0.2 3.2 3 0 0 3 3 3 0 RING-type zinc-finger zf-Apc11 PF12861.2 KFH47146.1 - 0.89 9.4 6.7 0.12 12.1 1.6 1.9 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger FAD_binding_7 PF03441.9 KFH47147.1 - 4.7e-103 344.2 0.0 7.5e-103 343.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KFH47147.1 - 5e-40 136.9 0.1 8.1e-40 136.2 0.1 1.3 1 0 0 1 1 1 1 DNA photolyase Usp PF00582.21 KFH47147.1 - 0.01 16.0 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 Universal stress protein family DUF605 PF04652.11 KFH47148.1 - 0.56 9.5 10.4 0.63 9.3 7.2 1.1 1 0 0 1 1 1 0 Vta1 like DivIC PF04977.10 KFH47149.1 - 0.0022 17.4 4.1 0.082 12.3 0.2 2.3 2 0 0 2 2 2 1 Septum formation initiator DUF972 PF06156.8 KFH47149.1 - 0.0089 16.3 6.9 2.3 8.5 0.2 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF972) bZIP_1 PF00170.16 KFH47149.1 - 0.019 14.8 12.5 1 9.3 3.7 2.6 2 0 0 2 2 2 0 bZIP transcription factor CENP-Q PF13094.1 KFH47149.1 - 0.052 13.5 18.2 0.051 13.5 4.5 3.1 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Lebercilin PF15619.1 KFH47149.1 - 0.1 11.9 11.1 0.19 11.1 0.8 2.3 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease TMF_DNA_bd PF12329.3 KFH47149.1 - 0.18 11.6 14.3 0.27 11.0 1.3 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 KFH47149.1 - 0.22 11.1 5.8 2 7.9 1.0 2.3 2 0 0 2 2 2 0 IncA protein Sec34 PF04136.10 KFH47149.1 - 0.37 10.4 2.1 0.47 10.1 0.1 1.9 2 0 0 2 2 2 0 Sec34-like family Prefoldin_2 PF01920.15 KFH47149.1 - 0.63 9.8 10.4 6.2 6.6 0.2 2.3 2 0 0 2 2 2 0 Prefoldin subunit DUF4201 PF13870.1 KFH47149.1 - 0.63 9.4 11.8 0.41 10.0 3.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF4164 PF13747.1 KFH47149.1 - 1.1 9.4 10.0 0.12 12.4 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Dor1 PF04124.7 KFH47149.1 - 1.2 7.5 5.7 22 3.3 2.2 2.7 2 1 0 2 2 2 0 Dor1-like family FlaC_arch PF05377.6 KFH47149.1 - 1.4 8.9 4.5 0.94 9.4 0.8 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF3166 PF11365.3 KFH47149.1 - 1.4 9.4 10.2 0.11 12.9 2.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3166) DUF4446 PF14584.1 KFH47149.1 - 1.9 8.3 5.7 4.8 7.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) TBPIP PF07106.8 KFH47149.1 - 2.3 7.7 7.9 11 5.5 1.7 2.3 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ADIP PF11559.3 KFH47149.1 - 2.7 7.8 11.7 8.3 6.2 0.7 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding CASP_C PF08172.7 KFH47149.1 - 2.8 6.9 10.0 0.11 11.5 1.0 2.6 3 0 0 3 3 3 0 CASP C terminal Ax_dynein_light PF10211.4 KFH47149.1 - 3.6 7.3 10.7 8.6 6.1 0.5 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain CCDC-167 PF15188.1 KFH47149.1 - 5.4 7.0 10.2 6.4 6.7 2.2 2.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Snapin_Pallidin PF14712.1 KFH47149.1 - 8 6.8 7.7 7.1 7.0 0.3 2.5 2 0 0 2 2 2 0 Snapin/Pallidin Slx4 PF09494.5 KFH47150.1 - 2.9e-23 81.3 0.0 4.7e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 Slx4 endonuclease AT_hook PF02178.14 KFH47150.1 - 1.6e-05 24.0 30.5 0.075 12.7 3.1 4.8 3 0 0 3 3 3 3 AT hook motif HLH PF00010.21 KFH47151.1 - 1.9e-06 27.4 0.0 3.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Mito_fiss_reg PF05308.6 KFH47151.1 - 9.5 5.4 28.0 0.33 10.2 9.4 3.1 3 0 0 3 3 3 0 Mitochondrial fission regulator Sugar_tr PF00083.19 KFH47152.1 - 4.3e-80 269.4 10.4 5e-80 269.2 7.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH47152.1 - 3.6e-30 104.8 36.6 1.4e-27 96.3 12.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFH47152.1 - 1.6e-05 23.3 3.6 2.1e-05 22.9 1.0 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) cNMP_binding PF00027.24 KFH47155.1 - 4.9e-37 125.6 0.0 8.2e-19 67.2 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 KFH47155.1 - 2e-12 45.7 8.0 0.17 12.0 0.0 8.2 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.2 KFH47155.1 - 9.7e-07 28.2 0.1 0.6 9.7 0.0 4.4 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFH47155.1 - 3.7e-06 26.2 5.4 3.9 7.8 0.1 6.8 6 1 1 7 7 7 2 Leucine Rich Repeat F-box-like PF12937.2 KFH47155.1 - 6.5e-06 25.7 0.9 2.8e-05 23.7 0.6 2.1 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 KFH47155.1 - 9e-06 25.3 0.7 0.062 13.0 0.1 3.8 3 1 0 3 3 3 2 Leucine rich repeat F-box PF00646.28 KFH47155.1 - 1.9e-05 24.1 0.5 1.9e-05 24.1 0.3 2.3 2 0 0 2 2 2 1 F-box domain DUF1537 PF07005.6 KFH47155.1 - 0.029 14.0 0.3 0.05 13.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF1537 LRR_7 PF13504.1 KFH47155.1 - 0.2 11.9 10.3 33 5.3 0.1 5.8 6 0 0 6 6 6 0 Leucine rich repeat 2-Hacid_dh_C PF02826.14 KFH47156.1 - 1.3e-46 157.9 0.0 7.7e-46 155.4 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFH47156.1 - 0.00021 20.7 0.0 0.00028 20.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KFH47156.1 - 0.027 14.3 0.1 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase SAP PF02037.22 KFH47156.1 - 0.58 9.7 2.7 40 3.8 0.1 3.6 4 0 0 4 4 4 0 SAP domain Vps5 PF09325.5 KFH47157.1 - 6.1e-13 48.5 1.1 8.7e-13 48.0 0.8 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 KFH47157.1 - 1.2e-08 34.7 0.0 2.6e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 PX domain TPR_12 PF13424.1 KFH47157.1 - 0.036 14.0 0.9 0.77 9.7 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat ECM11 PF15463.1 KFH47158.1 - 2.7e-40 137.8 8.4 8.5e-40 136.2 5.8 1.9 1 0 0 1 1 1 1 Extracellular mutant protein 11 AAA_13 PF13166.1 KFH47158.1 - 0.066 11.6 0.6 0.091 11.2 0.4 1.1 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 KFH47158.1 - 1.1 8.8 3.8 1.7 8.1 2.7 1.3 1 0 0 1 1 1 0 IncA protein CIAPIN1 PF05093.8 KFH47159.1 - 0.11 12.5 0.8 0.14 12.2 0.5 1.1 1 0 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Methyltransf_16 PF10294.4 KFH47160.1 - 5.3e-13 48.7 0.0 1.9e-07 30.7 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase CM_2 PF01817.16 KFH47161.1 - 1.1e-09 38.2 0.2 2.7e-06 27.3 0.0 3.0 2 1 0 2 2 2 2 Chorismate mutase type II Mak16 PF04874.9 KFH47161.1 - 0.039 14.0 0.0 0.47 10.5 0.0 2.6 2 0 0 2 2 2 0 Mak16 protein C-terminal region DUF4066 PF13278.1 KFH47162.1 - 2e-25 88.9 0.0 3.1e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KFH47162.1 - 3.2e-14 52.6 0.0 4.5e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 KFH47162.1 - 0.0012 18.3 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I JAB PF01398.16 KFH47164.1 - 2.8e-09 36.7 0.0 8e-09 35.2 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KFH47164.1 - 3.3e-06 27.1 0.1 1.3e-05 25.2 0.1 1.8 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function TFIIS_C PF01096.13 KFH47165.1 - 6.7e-16 57.6 1.4 6.7e-16 57.6 0.9 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KFH47165.1 - 0.00035 20.1 9.6 0.00055 19.5 1.8 3.1 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Spt4 PF06093.8 KFH47165.1 - 0.0025 17.6 2.0 0.0071 16.2 1.4 1.8 1 1 0 1 1 1 1 Spt4/RpoE2 zinc finger Mu-like_Com PF10122.4 KFH47165.1 - 0.0037 16.2 2.7 0.069 12.2 0.0 2.5 2 0 0 2 2 2 1 Mu-like prophage protein Com Zn_Tnp_IS1595 PF12760.2 KFH47165.1 - 0.027 14.2 0.6 0.027 14.2 0.4 2.8 2 1 1 3 3 2 0 Transposase zinc-ribbon domain Zn_Tnp_IS1 PF03811.8 KFH47165.1 - 0.04 13.4 2.5 0.081 12.4 0.1 2.5 2 0 0 2 2 2 0 InsA N-terminal domain Zn-ribbon_8 PF09723.5 KFH47165.1 - 0.041 13.8 12.8 0.97 9.4 0.0 3.3 3 0 0 3 3 3 0 Zinc ribbon domain tRNA-synt_1f PF01921.13 KFH47165.1 - 0.047 12.3 0.4 0.067 11.8 0.1 1.4 1 1 1 2 2 2 0 tRNA synthetases class I (K) zf-C4_Topoisom PF01396.14 KFH47165.1 - 0.065 12.7 1.1 0.065 12.7 0.8 3.3 2 2 1 3 3 3 0 Topoisomerase DNA binding C4 zinc finger DNA_RNApol_7kD PF03604.8 KFH47165.1 - 0.13 11.7 15.2 0.094 12.2 2.7 3.1 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.2 KFH47165.1 - 0.23 11.3 13.8 0.075 12.8 1.8 2.8 2 1 0 2 2 2 0 Double zinc ribbon Ribosomal_S27e PF01667.12 KFH47165.1 - 0.41 10.2 0.1 0.41 10.2 0.1 3.0 3 1 0 3 3 3 0 Ribosomal protein S27 C1_3 PF07649.7 KFH47165.1 - 0.47 10.5 0.3 0.47 10.5 0.2 2.9 4 0 0 4 4 3 0 C1-like domain Terminase_GpA PF05876.7 KFH47165.1 - 0.5 8.6 2.9 0.22 9.8 0.7 1.3 1 1 0 1 1 1 0 Phage terminase large subunit (GpA) DUF2072 PF09845.4 KFH47165.1 - 0.79 9.6 6.3 9.3 6.1 1.6 2.3 1 1 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) HypA PF01155.14 KFH47165.1 - 1.4 8.6 11.0 1.2 8.8 1.4 2.5 2 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family C1_1 PF00130.17 KFH47165.1 - 2 8.2 9.9 0.41 10.4 0.9 2.7 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ogr_Delta PF04606.7 KFH47165.1 - 3.4 7.4 10.9 0.94 9.1 2.3 3.0 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger ABC_tran PF00005.22 KFH47166.1 - 5.1e-49 166.0 0.0 3.6e-29 101.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KFH47166.1 - 2.5e-30 105.8 19.3 1.6e-16 60.5 0.2 2.7 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 KFH47166.1 - 3.7e-10 39.4 1.1 0.0031 16.7 0.3 4.2 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFH47166.1 - 6.8e-09 36.0 0.2 0.27 11.1 0.0 4.3 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 KFH47166.1 - 7.4e-09 36.2 0.2 4.7e-05 23.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KFH47166.1 - 1.2e-07 31.3 0.0 0.0061 15.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KFH47166.1 - 3.6e-07 29.6 1.1 0.0087 15.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_10 PF12846.2 KFH47166.1 - 5e-05 22.8 0.9 0.18 11.1 0.1 2.5 2 0 0 2 2 2 2 AAA-like domain FtsK_SpoIIIE PF01580.13 KFH47166.1 - 5.6e-05 22.7 0.0 0.03 13.7 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF258 PF03193.11 KFH47166.1 - 6.5e-05 22.1 0.1 0.16 11.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 KFH47166.1 - 8e-05 23.1 0.1 0.37 11.3 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein SbcCD_C PF13558.1 KFH47166.1 - 0.00024 20.9 0.1 1.1 9.2 0.0 2.8 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 KFH47166.1 - 0.00026 20.6 0.0 0.063 13.0 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 KFH47166.1 - 0.00036 20.2 0.2 0.61 9.7 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_17 PF13207.1 KFH47166.1 - 0.00045 21.0 1.2 0.46 11.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 KFH47166.1 - 0.00068 19.5 3.5 0.0034 17.2 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_22 PF13401.1 KFH47166.1 - 0.0008 19.5 2.9 0.89 9.6 0.2 3.4 3 1 0 3 3 3 1 AAA domain MobB PF03205.9 KFH47166.1 - 0.0011 18.7 1.4 0.099 12.3 0.1 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 KFH47166.1 - 0.0012 17.7 2.3 0.61 8.9 0.2 2.8 3 0 0 3 3 3 2 Type II/IV secretion system protein cobW PF02492.14 KFH47166.1 - 0.0019 17.7 1.6 0.95 8.8 0.5 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.7 KFH47166.1 - 0.0021 17.3 2.6 0.49 9.6 0.1 2.3 2 0 0 2 2 2 2 Poxvirus A32 protein MMR_HSR1 PF01926.18 KFH47166.1 - 0.0036 17.2 0.1 0.13 12.2 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.1 KFH47166.1 - 0.004 17.4 0.1 2.1 8.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 KFH47166.1 - 0.0044 16.5 0.0 1.8 8.0 0.0 2.6 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 KFH47166.1 - 0.0087 14.9 1.2 3.2 6.5 0.1 3.3 3 0 0 3 3 3 1 NB-ARC domain ATP-synt_ab PF00006.20 KFH47166.1 - 0.025 14.0 0.1 5.1 6.5 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.1 KFH47166.1 - 0.027 14.3 0.0 5.1 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 KFH47166.1 - 0.042 13.5 0.6 7.9 6.1 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_16 PF13191.1 KFH47166.1 - 0.057 13.3 7.9 1.7 8.6 0.3 3.2 2 1 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.18 KFH47166.1 - 0.066 13.0 3.7 2.6 7.8 0.2 2.4 2 0 0 2 2 2 0 Dynamin family DUF2075 PF09848.4 KFH47166.1 - 0.11 11.4 0.2 0.91 8.4 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Septin PF00735.13 KFH47166.1 - 0.12 11.3 0.1 14 4.5 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_14 PF13173.1 KFH47166.1 - 0.13 12.1 0.0 18 5.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KFH47166.1 - 0.13 11.7 0.8 7.4 6.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KFH47166.1 - 0.13 11.8 0.0 3.4 7.3 0.0 2.5 3 0 0 3 3 2 0 Archaeal ATPase Zeta_toxin PF06414.7 KFH47166.1 - 0.16 11.0 0.5 3.4 6.7 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin ATP_bind_1 PF03029.12 KFH47166.1 - 0.37 10.2 1.9 5.6 6.4 0.1 2.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein TrwB_AAD_bind PF10412.4 KFH47166.1 - 0.46 9.0 2.0 9.7 4.6 0.0 3.1 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain DAP3 PF10236.4 KFH47166.1 - 0.67 8.8 2.1 9.8 4.9 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_15 PF13175.1 KFH47166.1 - 0.82 8.6 0.0 3.5 6.5 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain CbiA PF01656.18 KFH47166.1 - 1.2 8.5 2.8 11 5.3 0.2 2.5 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Hemerythrin PF01814.18 KFH47167.1 - 1.3e-08 35.0 0.4 1.7e-08 34.7 0.3 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Ank_2 PF12796.2 KFH47168.1 - 1.1e-23 83.2 0.2 6.1e-12 45.7 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KFH47168.1 - 6.5e-19 66.1 1.2 0.0051 16.9 0.0 6.4 5 1 1 6 6 6 4 Ankyrin repeat Ank PF00023.25 KFH47168.1 - 1e-16 59.7 1.3 0.0035 17.0 0.1 6.1 4 2 2 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 KFH47168.1 - 2.9e-16 59.4 3.5 0.00057 20.3 0.0 6.2 3 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFH47168.1 - 4.5e-11 42.6 7.4 0.00021 21.4 0.0 5.1 3 2 1 5 5 5 3 Ankyrin repeats (many copies) adh_short PF00106.20 KFH47169.1 - 1.9e-60 203.6 8.0 6.5e-30 104.2 0.8 2.4 2 0 0 2 2 2 2 short chain dehydrogenase MaoC_dehydratas PF01575.14 KFH47169.1 - 1.3e-31 108.5 0.0 3e-31 107.3 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain KR PF08659.5 KFH47169.1 - 1.6e-28 99.5 2.1 1.2e-13 51.0 0.1 2.5 2 0 0 2 2 2 2 KR domain MaoC_dehydrat_N PF13452.1 KFH47169.1 - 3.1e-06 27.0 0.0 0.00028 20.6 0.0 2.5 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.14 KFH47169.1 - 0.00037 19.5 0.3 0.03 13.3 0.2 2.5 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Neural_ProG_Cyt PF06567.6 KFH47169.1 - 0.031 14.4 0.1 0.087 12.9 0.1 1.7 1 0 0 1 1 1 0 Neural chondroitin sulphate proteoglycan cytoplasmic domain Eno-Rase_NADH_b PF12242.3 KFH47169.1 - 0.29 10.9 3.6 0.19 11.5 0.1 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF4161 PF13722.1 KFH47169.1 - 0.3 11.3 1.3 6.9 7.0 0.1 2.3 2 0 0 2 2 2 0 C-terminal domain on CstA (DUF4161) 3HCDH_N PF02737.13 KFH47169.1 - 0.92 9.1 7.4 6.4 6.3 0.5 2.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4246 PF14033.1 KFH47170.1 - 1.3e-155 518.8 0.0 1.6e-155 518.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-Fe_Oxy_2 PF10014.4 KFH47170.1 - 0.095 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe dioxygenase Phosphorylase PF00343.15 KFH47171.1 - 0 1068.8 0.0 0 1068.6 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Coatomer_b_Cpla PF14806.1 KFH47171.1 - 0.053 13.2 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform EF-hand_7 PF13499.1 KFH47172.1 - 4.2e-29 100.4 11.7 1.1e-12 47.8 0.4 3.3 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 KFH47172.1 - 2e-25 86.0 11.3 3.2e-08 32.2 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 KFH47172.1 - 1.4e-23 80.6 3.7 9e-06 25.1 0.1 5.1 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 KFH47172.1 - 5.4e-17 60.2 13.7 2.4e-05 23.4 0.0 4.6 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 KFH47172.1 - 3.1e-16 58.7 10.9 5.7e-06 25.8 0.7 4.0 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 KFH47172.1 - 3.1e-09 36.4 8.5 0.0032 17.1 0.1 4.1 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KFH47172.1 - 4.2e-05 23.3 0.5 0.013 15.3 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain Toprim PF01751.17 KFH47172.1 - 0.0023 17.8 0.0 1.3 9.0 0.0 2.3 1 1 1 2 2 2 2 Toprim domain EF-hand_2 PF09068.6 KFH47172.1 - 0.0031 17.5 0.1 0.97 9.5 0.0 3.2 3 1 0 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.4 KFH47172.1 - 0.01 15.8 2.5 0.76 9.8 0.1 3.1 2 2 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF1679 PF07914.6 KFH47172.1 - 0.019 13.6 0.3 2 6.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EF-hand_10 PF14788.1 KFH47172.1 - 0.024 14.2 2.8 2.4 7.8 0.0 3.9 4 0 0 4 4 4 0 EF hand Toprim_2 PF13155.1 KFH47172.1 - 0.045 14.0 0.3 2.1 8.7 0.2 2.9 1 1 1 2 2 2 0 Toprim-like PMBR PF09373.5 KFH47172.1 - 0.15 12.0 0.0 13 5.8 0.0 3.1 4 0 0 4 4 4 0 Pseudomurein-binding repeat Methyltransf_23 PF13489.1 KFH47173.1 - 1.4e-14 54.1 0.0 2.2e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH47173.1 - 4.4e-09 36.6 0.0 3.9e-08 33.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH47173.1 - 5.1e-09 35.8 0.0 7.8e-08 32.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH47173.1 - 5e-08 33.4 0.0 1.6e-06 28.6 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH47173.1 - 8.9e-07 29.3 0.0 2.5e-06 27.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 KFH47173.1 - 0.0013 18.7 0.0 0.0028 17.6 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 KFH47173.1 - 0.0068 15.6 0.0 0.0093 15.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.9 KFH47173.1 - 0.027 13.8 0.0 0.054 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.1 KFH47173.1 - 0.035 14.4 0.0 0.09 13.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain DHC_N1 PF08385.7 KFH47174.1 - 3.6e-187 623.3 5.6 3.6e-187 623.3 3.9 5.2 5 1 1 6 6 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 KFH47174.1 - 1.2e-128 429.1 8.8 1.2e-128 429.1 6.1 5.7 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 KFH47174.1 - 1.2e-107 360.7 0.0 4.5e-107 358.8 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 KFH47174.1 - 4.7e-77 258.6 0.0 1.3e-76 257.1 0.0 1.8 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 KFH47174.1 - 3.3e-44 150.4 0.0 8.9e-44 149.0 0.0 1.8 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 KFH47174.1 - 1.7e-40 138.6 0.0 2.4e-39 134.9 0.0 2.6 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 KFH47174.1 - 3.3e-39 134.6 9.3 7.3e-39 133.4 6.5 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 KFH47174.1 - 6.9e-31 106.8 0.0 9.2e-12 44.8 0.0 6.3 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 KFH47174.1 - 4.9e-20 71.7 0.0 8.2e-19 67.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 KFH47174.1 - 3.4e-15 56.3 0.0 0.016 15.3 0.0 5.8 5 0 0 5 5 4 4 AAA domain AAA PF00004.24 KFH47174.1 - 3.7e-14 53.0 0.0 0.0009 19.4 0.0 4.8 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KFH47174.1 - 3.7e-11 43.8 0.1 0.046 14.5 0.0 6.4 5 0 0 5 5 5 2 AAA domain AAA_33 PF13671.1 KFH47174.1 - 3.2e-10 40.0 1.0 0.28 11.0 0.0 5.6 5 0 0 5 5 5 3 AAA domain AAA_18 PF13238.1 KFH47174.1 - 3.8e-09 36.9 0.6 0.043 14.1 0.0 6.1 6 0 0 6 6 5 2 AAA domain AAA_16 PF13191.1 KFH47174.1 - 1.5e-06 28.3 26.2 0.15 12.0 0.1 9.8 8 4 2 10 10 10 2 AAA ATPase domain T2SE PF00437.15 KFH47174.1 - 2.2e-06 26.7 0.0 0.053 12.4 0.0 3.9 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA_29 PF13555.1 KFH47174.1 - 2.5e-06 26.9 0.0 0.46 10.0 0.0 3.8 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_14 PF13173.1 KFH47174.1 - 1.1e-05 25.2 0.0 0.28 11.1 0.0 5.1 6 0 0 6 6 4 1 AAA domain AAA_19 PF13245.1 KFH47174.1 - 3.6e-05 23.4 0.2 0.89 9.3 0.0 4.5 4 0 0 4 4 4 1 Part of AAA domain ABC_tran PF00005.22 KFH47174.1 - 7.2e-05 23.0 1.2 5 7.4 0.0 5.5 4 0 0 4 4 4 1 ABC transporter BRE1 PF08647.6 KFH47174.1 - 0.00046 20.1 3.6 0.00046 20.1 2.5 4.8 5 0 0 5 5 4 1 BRE1 E3 ubiquitin ligase FtsK_SpoIIIE PF01580.13 KFH47174.1 - 0.0012 18.3 0.0 21 4.5 0.0 4.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family Mg_chelatase PF01078.16 KFH47174.1 - 0.0014 17.8 4.1 0.5 9.4 0.0 3.8 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 KFH47174.1 - 0.0043 16.1 5.5 0.97 8.4 0.0 4.7 5 0 0 5 5 4 1 Zeta toxin RNA_helicase PF00910.17 KFH47174.1 - 0.0059 16.7 0.6 36 4.5 0.0 4.8 5 0 0 5 5 4 0 RNA helicase AAA_25 PF13481.1 KFH47174.1 - 0.0065 15.8 0.0 0.46 9.8 0.0 3.3 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KFH47174.1 - 0.012 15.2 0.1 6.8 6.3 0.0 3.6 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B DUF1446 PF07287.6 KFH47177.1 - 3.7e-130 433.6 0.6 4.4e-130 433.3 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) Ras PF00071.17 KFH47178.1 - 3.1e-42 143.7 0.0 6.5e-42 142.6 0.0 1.5 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KFH47178.1 - 6.2e-15 55.7 0.0 9.2e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFH47178.1 - 2.4e-10 39.9 0.0 1.7e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family PduV-EutP PF10662.4 KFH47178.1 - 0.0001 21.7 0.0 0.19 11.2 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 KFH47178.1 - 0.00073 18.7 0.0 0.00099 18.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFH47178.1 - 0.0024 17.8 0.0 0.0043 17.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 KFH47178.1 - 0.0035 17.2 0.0 0.0069 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KFH47178.1 - 0.016 15.3 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 KFH47178.1 - 0.023 13.9 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 KFH47178.1 - 0.028 14.7 0.1 0.21 11.8 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_28 PF13521.1 KFH47178.1 - 0.03 14.3 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KFH47178.1 - 0.039 13.1 0.0 0.066 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 KFH47178.1 - 0.048 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 KFH47178.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.9 KFH47178.1 - 0.15 11.7 0.0 0.47 10.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) FAD_binding_4 PF01565.18 KFH47178.1 - 8.1 5.9 7.0 5.1 6.5 0.2 3.0 3 0 0 3 3 3 0 FAD binding domain vMSA PF00695.14 KFH47179.1 - 2.1 7.4 6.8 2.3 7.3 4.7 1.0 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus ACPS PF01648.15 KFH47180.1 - 2.8e-12 46.4 0.0 3.8e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Cullin PF00888.17 KFH47181.1 - 2.8e-205 683.3 10.5 4e-205 682.7 7.3 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KFH47181.1 - 3.3e-27 94.1 5.6 3.3e-27 94.1 3.9 2.6 3 0 0 3 3 3 1 Cullin protein neddylation domain WGG PF10273.4 KFH47181.1 - 0.04 13.9 3.0 18 5.4 0.0 4.1 4 0 0 4 4 4 0 Pre-rRNA-processing protein TSR2 E1_DerP2_DerF2 PF02221.10 KFH47182.1 - 2.8e-26 92.3 0.2 3.3e-26 92.1 0.1 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 KFH47182.1 - 0.0071 16.3 0.1 0.025 14.5 0.1 1.8 1 1 0 1 1 1 1 ML-like domain Bax1-I PF01027.15 KFH47183.1 - 3.1e-32 111.8 9.4 4.7e-32 111.2 6.5 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 YbgT_YccB PF08173.6 KFH47183.1 - 0.17 11.7 0.3 0.17 11.7 0.2 2.2 2 0 0 2 2 2 0 Membrane bound YbgT-like protein zf-C2H2_6 PF13912.1 KFH47184.1 - 0.0014 18.4 0.3 0.0014 18.4 0.2 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-BED PF02892.10 KFH47184.1 - 0.57 9.9 7.3 0.034 13.9 0.7 2.1 2 0 0 2 2 2 0 BED zinc finger Zn_clus PF00172.13 KFH47184.1 - 6.2 6.8 13.9 0.3 11.0 5.6 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_2_N PF02837.13 KFH47185.1 - 1.8e-12 47.1 0.1 5.6e-12 45.5 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KFH47185.1 - 8.4e-10 39.0 0.0 2.5e-09 37.5 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 KFH47185.1 - 0.00029 19.8 0.0 0.00048 19.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain His_Phos_1 PF00300.17 KFH47186.1 - 5.1e-09 36.4 0.0 6.3e-07 29.6 0.0 2.4 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) DUF1993 PF09351.5 KFH47187.1 - 5.1e-41 140.2 0.0 5.8e-41 140.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) RCR PF12273.3 KFH47188.1 - 0.016 15.7 0.2 0.042 14.3 0.1 1.7 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red SH3_9 PF14604.1 KFH47188.1 - 0.017 14.6 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain Glycophorin_A PF01102.13 KFH47188.1 - 0.086 12.6 0.0 0.086 12.6 0.0 2.4 3 0 0 3 3 3 0 Glycophorin A SKG6 PF08693.5 KFH47188.1 - 0.091 12.0 0.1 0.24 10.7 0.0 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Cation_efflux PF01545.16 KFH47189.1 - 7.8e-58 195.8 0.4 7.8e-58 195.8 0.3 1.4 2 0 0 2 2 2 1 Cation efflux family Zip PF02535.17 KFH47189.1 - 0.016 14.2 38.7 1.5 7.7 23.7 3.3 2 1 0 2 2 2 0 ZIP Zinc transporter Glyco_hydro_17 PF00332.13 KFH47190.1 - 4.1e-05 22.7 0.4 0.0002 20.5 0.2 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 Glyco_hydro_cc PF11790.3 KFH47190.1 - 0.0048 16.3 0.1 0.0087 15.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Peptidase_C13 PF01650.13 KFH47192.1 - 1.3e-41 142.6 0.1 1.8e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family ADH_zinc_N PF00107.21 KFH47194.1 - 3.1e-24 84.9 0.1 5.4e-24 84.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFH47194.1 - 9.6e-07 29.7 0.0 4.7e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF89 PF01937.14 KFH47194.1 - 0.074 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF89 TP_methylase PF00590.15 KFH47195.1 - 6.1e-21 75.0 0.0 1e-20 74.3 0.0 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases SpoVAD PF07451.6 KFH47195.1 - 0.11 10.9 0.0 0.18 10.2 0.0 1.3 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) Ribosomal_L14 PF00238.14 KFH47196.1 - 2.7e-32 111.0 0.0 3e-32 110.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Cupredoxin_1 PF13473.1 KFH47197.1 - 0.00078 19.3 0.1 0.0018 18.1 0.0 1.6 2 0 0 2 2 2 1 Cupredoxin-like domain DUF4448 PF14610.1 KFH47197.1 - 0.028 13.9 0.0 0.049 13.1 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) CENP-B_dimeris PF09026.5 KFH47197.1 - 2.2 8.5 10.2 0.23 11.7 3.1 2.3 3 0 0 3 3 3 0 Centromere protein B dimerisation domain CDC45 PF02724.9 KFH47197.1 - 3.6 5.4 5.5 5.1 4.9 3.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.7 KFH47197.1 - 3.7 7.1 8.0 4.7 6.8 5.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein UQ_con PF00179.21 KFH47198.1 - 8.6e-36 122.4 0.0 1e-35 122.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme WD40 PF00400.27 KFH47199.1 - 2.9e-39 131.5 7.5 8.9e-10 38.0 0.4 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Cupin_8 PF13621.1 KFH47199.1 - 2.7e-36 125.3 0.0 5.8e-36 124.2 0.0 1.5 1 0 0 1 1 1 1 Cupin-like domain Nup160 PF11715.3 KFH47199.1 - 4.9e-06 24.9 6.1 0.062 11.4 0.1 4.1 2 2 0 3 3 3 3 Nucleoporin Nup120/160 Cupin_4 PF08007.7 KFH47199.1 - 0.00025 20.3 0.1 0.015 14.5 0.0 3.1 3 0 0 3 3 3 1 Cupin superfamily protein JmjC PF02373.17 KFH47199.1 - 0.00052 20.2 0.0 0.0024 18.0 0.0 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase Nucleoporin_N PF08801.6 KFH47199.1 - 0.0013 17.5 0.0 0.36 9.5 0.0 3.2 3 0 0 3 3 3 1 Nup133 N terminal like DUF3552 PF12072.3 KFH47199.1 - 0.97 8.6 5.6 1.7 7.8 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Ribosomal_S21e PF01249.13 KFH47200.1 - 6.9e-40 134.8 0.1 7.7e-40 134.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e MFS_1 PF07690.11 KFH47201.1 - 1.3e-45 155.6 40.1 1.3e-45 155.6 27.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH47201.1 - 7.8e-13 47.8 24.4 1.3e-12 47.0 16.9 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 KFH47201.1 - 0.0019 16.4 2.5 0.0019 16.4 1.7 1.6 2 0 0 2 2 2 1 Transmembrane secretion effector OATP PF03137.15 KFH47201.1 - 0.016 13.3 9.2 0.014 13.5 1.2 2.6 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family CoA_transf_3 PF02515.12 KFH47202.1 - 2.8e-60 202.8 0.0 4.7e-60 202.1 0.0 1.4 1 0 0 1 1 1 1 CoA-transferase family III SNF5 PF04855.7 KFH47203.1 - 3.3e-85 285.4 0.0 4.5e-85 285.0 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 KFH47203.1 - 3.5e-05 23.0 1.6 8.4e-05 21.8 1.1 1.7 1 0 0 1 1 1 1 GATA zinc finger Herpes_capsid PF06112.6 KFH47203.1 - 0.035 14.1 1.1 0.073 13.1 0.8 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF4266 PF14086.1 KFH47204.1 - 0.013 15.9 1.1 0.029 14.8 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4266) UPF0547 PF10571.4 KFH47204.1 - 1 9.1 8.7 0.85 9.3 0.2 2.5 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Fungal_trans PF04082.13 KFH47205.1 - 1.2e-16 60.4 0.0 1.8e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH47205.1 - 3.6e-06 26.7 12.7 5.7e-06 26.1 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RIC3 PF15361.1 KFH47205.1 - 3.8 7.7 7.0 8.8 6.5 4.2 2.2 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 CBFD_NFYB_HMF PF00808.18 KFH47206.1 - 1.4e-27 95.5 0.4 1.7e-26 92.0 0.8 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFH47206.1 - 3.2e-07 30.3 0.1 5.3e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 KFH47206.1 - 0.00058 19.6 0.0 0.00089 19.0 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 KFH47206.1 - 0.0016 18.0 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 KFH47206.1 - 0.055 13.7 0.1 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A DUF3123 PF11321.3 KFH47207.1 - 0.079 13.2 0.5 0.079 13.2 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) Cmc1 PF08583.5 KFH47208.1 - 3.7e-15 55.4 4.0 4.4e-15 55.1 2.8 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Gemini_AL2 PF01440.11 KFH47208.1 - 0.053 13.6 0.2 0.071 13.2 0.1 1.2 1 0 0 1 1 1 0 Geminivirus AL2 protein Rho_Binding PF08912.6 KFH47208.1 - 0.053 13.8 0.3 0.069 13.4 0.1 1.5 1 1 0 1 1 1 0 Rho Binding GCK PF07802.6 KFH47208.1 - 0.19 11.8 0.9 0.23 11.5 0.6 1.3 1 0 0 1 1 1 0 GCK domain COX17 PF05051.8 KFH47208.1 - 0.47 10.5 2.5 17 5.5 0.1 2.3 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) SURF4 PF02077.10 KFH47209.1 - 8.3e-95 317.1 10.3 4.8e-74 249.0 3.9 2.0 2 0 0 2 2 2 2 SURF4 family Peptidase_A24 PF01478.13 KFH47209.1 - 0.0039 17.3 8.3 0.3 11.2 0.6 2.6 2 0 0 2 2 2 2 Type IV leader peptidase family HR_lesion PF05514.6 KFH47209.1 - 0.028 14.2 2.9 0.13 12.0 0.0 3.0 2 2 1 4 4 4 0 HR-like lesion-inducing Med16 PF11635.3 KFH47210.1 - 3.3e-97 326.2 0.0 4e-97 325.9 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 TMEM154 PF15102.1 KFH47211.1 - 0.0031 17.2 0.4 0.008 15.8 0.3 1.7 1 0 0 1 1 1 1 TMEM154 protein family Kelch_5 PF13854.1 KFH47211.1 - 0.034 14.1 1.5 25 4.9 0.0 4.2 5 0 0 5 5 5 0 Kelch motif MtrF PF09472.5 KFH47211.1 - 0.096 11.9 0.9 0.19 11.0 0.6 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Kelch_4 PF13418.1 KFH47211.1 - 0.13 12.0 8.6 0.83 9.4 0.0 4.9 6 0 0 6 6 6 0 Galactose oxidase, central domain DUF1180 PF06679.7 KFH47211.1 - 0.23 11.3 0.1 0.23 11.3 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) MSA-2c PF12238.3 KFH47211.1 - 4.7 6.8 10.9 6.5 6.3 2.6 2.5 2 0 0 2 2 2 0 Merozoite surface antigen 2c Fungal_trans_2 PF11951.3 KFH47213.1 - 2.3e-79 266.7 0.8 3.1e-79 266.3 0.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH47213.1 - 1.4e-07 31.2 4.8 2.5e-07 30.4 3.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3859 PF12975.2 KFH47213.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3859) RCR PF12273.3 KFH47214.1 - 4.6e-17 62.7 14.8 9.5e-17 61.7 10.3 1.5 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Hum_adeno_E3A PF05393.6 KFH47214.1 - 0.019 14.6 0.4 0.029 14.0 0.3 1.4 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein Rhabdo_glycop PF00974.13 KFH47214.1 - 0.063 11.5 0.6 0.084 11.0 0.4 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein stn_TNFRSF12A PF12191.3 KFH47214.1 - 0.11 12.5 0.1 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Ammonium_transp PF00909.16 KFH47215.1 - 7.2e-119 396.8 25.3 8.3e-119 396.6 17.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DAD PF02109.11 KFH47216.1 - 8.7e-48 161.0 1.7 1.1e-47 160.8 1.2 1.0 1 0 0 1 1 1 1 DAD family Corona_S2 PF01601.11 KFH47217.1 - 5.5 4.9 20.5 7.5 4.5 14.2 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Mon1 PF03164.9 KFH47219.1 - 6.3e-115 384.0 0.0 7.4e-115 383.8 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Prefoldin_2 PF01920.15 KFH47220.1 - 9.3e-26 89.6 4.5 1.1e-25 89.4 3.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 KFH47220.1 - 0.0077 15.8 4.1 0.29 10.8 0.3 2.2 1 1 1 2 2 2 2 Prefoldin subunit IncA PF04156.9 KFH47220.1 - 0.023 14.3 5.2 0.054 13.0 3.6 1.5 1 1 0 1 1 1 0 IncA protein STAT_alpha PF01017.15 KFH47220.1 - 0.037 13.7 2.6 0.053 13.2 1.8 1.2 1 0 0 1 1 1 0 STAT protein, all-alpha domain PhaP_Bmeg PF09602.5 KFH47220.1 - 0.071 12.9 3.1 0.22 11.3 2.1 1.7 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF148 PF02520.12 KFH47220.1 - 0.098 12.4 3.5 0.67 9.7 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF148 Syntaxin-6_N PF09177.6 KFH47220.1 - 0.1 13.0 1.9 1.2 9.6 0.2 2.1 1 1 0 2 2 2 0 Syntaxin 6, N-terminal Cytochrom_B562 PF07361.6 KFH47220.1 - 0.12 12.7 5.2 0.4 11.0 0.6 2.1 2 0 0 2 2 2 0 Cytochrome b562 Tho2 PF11262.3 KFH47220.1 - 0.19 10.7 2.0 2.6 7.0 0.3 2.0 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Borrelia_lipo_1 PF05714.6 KFH47220.1 - 0.19 10.7 4.4 0.16 11.0 0.7 1.9 2 0 0 2 2 2 0 Borrelia burgdorferi virulent strain associated lipoprotein TPR_MLP1_2 PF07926.7 KFH47220.1 - 0.2 11.4 5.0 1.1 9.0 0.2 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein FliJ PF02050.11 KFH47220.1 - 0.4 10.7 6.6 1.3 9.0 0.6 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein DUF4337 PF14235.1 KFH47220.1 - 0.42 10.4 6.0 0.39 10.5 1.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Tup_N PF08581.5 KFH47220.1 - 0.61 10.3 3.7 2.2 8.5 0.5 2.1 2 0 0 2 2 2 0 Tup N-terminal HhH-GPD PF00730.20 KFH47222.1 - 0.0075 16.5 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Autophagy_act_C PF03987.10 KFH47223.1 - 4.5e-14 52.3 0.1 8.7e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain DUF1282 PF06930.7 KFH47224.1 - 0.00044 19.9 0.1 0.0005 19.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) AA_permease_2 PF13520.1 KFH47224.1 - 0.0062 15.1 0.1 0.007 14.9 0.1 1.0 1 0 0 1 1 1 1 Amino acid permease MARVEL PF01284.18 KFH47224.1 - 0.047 13.5 0.2 0.058 13.2 0.1 1.2 1 0 0 1 1 1 0 Membrane-associating domain Tetraspannin PF00335.15 KFH47224.1 - 0.14 11.4 1.4 0.16 11.1 1.0 1.1 1 0 0 1 1 1 0 Tetraspanin family TMEMspv1-c74-12 PF11044.3 KFH47224.1 - 4 7.0 6.9 1.7 8.2 0.4 2.1 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein LRR_6 PF13516.1 KFH47225.1 - 1.1e-13 49.6 4.3 0.00049 19.8 0.0 6.9 6 1 1 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.2 KFH47225.1 - 3.5e-10 39.2 12.1 0.00026 20.5 0.1 5.5 4 1 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFH47225.1 - 1e-05 24.8 5.2 5 7.5 0.0 6.1 6 1 1 7 7 7 2 Leucine Rich Repeat LRR_8 PF13855.1 KFH47225.1 - 0.0001 21.9 10.7 1.2 8.9 0.0 4.4 4 1 0 4 4 4 3 Leucine rich repeat LRR_7 PF13504.1 KFH47225.1 - 0.011 15.7 2.0 80 4.1 0.0 5.3 5 0 0 5 5 5 0 Leucine rich repeat Ank_2 PF12796.2 KFH47226.1 - 9.2e-55 182.9 0.5 1e-13 51.3 0.0 8.8 4 2 2 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KFH47226.1 - 1.4e-42 141.3 12.6 1.2e-05 24.8 0.0 12.1 13 0 0 13 13 13 9 Ankyrin repeat Ank_5 PF13857.1 KFH47226.1 - 1.1e-34 117.6 9.4 0.00016 21.8 0.0 10.8 10 0 0 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFH47226.1 - 3.1e-34 113.5 3.4 0.0025 17.8 0.0 11.8 11 0 0 11 11 11 8 Ankyrin repeat Ank_4 PF13637.1 KFH47226.1 - 8.7e-34 115.2 6.3 1.5e-05 25.3 0.0 10.4 9 1 1 10 10 10 8 Ankyrin repeats (many copies) Proteasome PF00227.21 KFH47227.1 - 2.2e-46 157.5 0.0 9.9e-31 106.5 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 KFH47227.1 - 3.6e-10 38.9 0.6 5.5e-10 38.3 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature COesterase PF00135.23 KFH47229.1 - 9.7e-89 298.4 0.4 2.6e-87 293.7 0.3 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFH47229.1 - 2.3e-05 24.0 0.1 0.00011 21.9 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFH47229.1 - 0.013 14.6 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFH47229.1 - 0.028 14.1 0.1 0.094 12.4 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family Herpes_US9 PF06072.6 KFH47229.1 - 0.68 9.8 3.0 1.3 8.8 2.1 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 MGC-24 PF05283.6 KFH47232.1 - 1.1e-06 28.5 4.0 1.1e-06 28.5 2.8 1.8 2 1 1 3 3 3 1 Multi-glycosylated core protein 24 (MGC-24) TMEM154 PF15102.1 KFH47232.1 - 9.3e-06 25.4 0.1 2.4e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 TMEM154 protein family Adeno_E3_CR2 PF02439.10 KFH47232.1 - 7.1e-05 22.2 0.8 0.00011 21.7 0.6 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Mid2 PF04478.7 KFH47232.1 - 0.0001 21.7 0.8 0.00081 18.8 0.0 2.2 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor Herpes_gE PF02480.11 KFH47232.1 - 0.00044 18.6 0.0 0.00068 18.0 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 KFH47232.1 - 0.00077 19.8 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DAP10 PF07213.6 KFH47232.1 - 0.0017 18.0 0.0 0.003 17.2 0.0 1.4 1 0 0 1 1 1 1 DAP10 membrane protein Plasmodium_Vir PF05795.6 KFH47232.1 - 0.0026 17.0 0.0 0.0038 16.4 0.0 1.2 1 0 0 1 1 1 1 Plasmodium vivax Vir protein DUF1180 PF06679.7 KFH47232.1 - 0.0027 17.6 0.3 0.0027 17.6 0.2 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1180) Podoplanin PF05808.6 KFH47232.1 - 0.0058 16.2 0.5 0.011 15.2 0.4 1.5 1 0 0 1 1 1 1 Podoplanin Protocadherin PF08374.6 KFH47232.1 - 0.031 13.9 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 Protocadherin DAG1 PF05454.6 KFH47232.1 - 0.037 13.2 0.0 0.076 12.1 0.0 1.4 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Rifin_STEVOR PF02009.11 KFH47232.1 - 0.038 13.6 0.0 0.053 13.1 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family DUF912 PF06024.7 KFH47232.1 - 0.042 13.9 0.0 0.085 12.9 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Phage_Coat_B PF05356.6 KFH47232.1 - 0.044 13.4 0.7 0.076 12.7 0.5 1.3 1 0 0 1 1 1 0 Phage Coat protein B TMEM51 PF15345.1 KFH47232.1 - 0.16 11.6 1.9 0.33 10.6 0.0 2.0 2 0 0 2 2 2 0 Transmembrane protein 51 DUF566 PF04484.7 KFH47232.1 - 7.1 6.0 10.5 18 4.7 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF566) PAD_M PF08527.5 KFH47234.1 - 0.086 12.2 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) middle domain BIR PF00653.16 KFH47234.1 - 1.6 9.2 6.6 10 6.6 0.5 3.0 3 1 0 3 3 3 0 Inhibitor of Apoptosis domain VPS9 PF02204.13 KFH47236.1 - 2.2e-31 107.9 0.1 3.8e-31 107.2 0.1 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 KFH47236.1 - 8.8e-10 37.8 0.1 8.6e-09 34.7 0.0 2.3 2 0 0 2 2 2 1 CUE domain Mito_fiss_reg PF05308.6 KFH47236.1 - 0.00097 18.5 0.9 0.00097 18.5 0.6 3.5 3 0 0 3 3 3 2 Mitochondrial fission regulator Sod_Fe_C PF02777.13 KFH47237.1 - 2e-10 40.4 0.0 4e-05 23.4 0.0 2.4 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain zf-C2H2 PF00096.21 KFH47238.1 - 2e-06 27.8 25.2 0.00052 20.1 0.3 5.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFH47238.1 - 0.019 15.2 0.4 0.019 15.2 0.3 5.3 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFH47238.1 - 0.34 10.8 0.1 0.34 10.8 0.0 2.9 4 0 0 4 4 4 0 C2H2-type zinc finger COX17 PF05051.8 KFH47239.1 - 2e-20 72.5 5.7 2.6e-20 72.1 4.0 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Ribosomal_60s PF00428.14 KFH47239.1 - 9.5 6.6 8.3 15 6.0 5.8 1.4 1 1 0 1 1 1 0 60s Acidic ribosomal protein DUF4110 PF13422.1 KFH47241.1 - 2.7e-28 97.6 0.5 2.7e-28 97.6 0.4 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.1 KFH47241.1 - 4.4e-25 87.2 19.3 6e-08 32.6 0.1 6.8 8 0 0 8 8 8 4 Galactose oxidase, central domain Kelch_4 PF13418.1 KFH47241.1 - 5.2e-23 80.5 14.1 3.6e-07 29.8 0.0 6.5 5 2 1 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KFH47241.1 - 1.6e-17 63.0 2.8 3.4e-05 23.6 0.0 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 KFH47241.1 - 1.8e-13 50.0 2.7 0.024 14.8 0.0 5.6 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 KFH47241.1 - 2.2e-11 43.0 2.2 0.01 15.6 0.0 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 KFH47241.1 - 9.4e-10 37.8 2.1 0.00022 20.6 0.1 4.9 5 0 0 5 5 5 2 Kelch motif DivIC PF04977.10 KFH47241.1 - 0.98 8.9 8.8 1.9 7.9 3.0 2.7 3 0 0 3 3 3 0 Septum formation initiator Plasmodium_Vir PF05795.6 KFH47241.1 - 3.5 6.7 8.3 1.7 7.7 1.4 2.2 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DEAD PF00270.24 KFH47242.1 - 1.1e-21 77.0 0.0 2.8e-21 75.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFH47242.1 - 1.9e-16 59.6 0.0 5.4e-15 55.0 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RQC PF09382.5 KFH47242.1 - 2.5e-11 43.2 0.1 1.3e-10 40.9 0.0 2.1 2 0 0 2 2 2 1 RQC domain ResIII PF04851.10 KFH47242.1 - 5.2e-05 23.1 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HRDC PF00570.18 KFH47242.1 - 0.00026 20.6 0.0 0.00075 19.1 0.0 1.8 1 0 0 1 1 1 1 HRDC domain SNF2_N PF00176.18 KFH47242.1 - 0.0012 17.7 0.2 0.0045 15.8 0.0 2.0 2 1 0 2 2 2 1 SNF2 family N-terminal domain E1-E2_ATPase PF00122.15 KFH47243.1 - 9.6e-16 57.5 0.0 1.8e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KFH47243.1 - 1.6e-13 51.5 0.0 3.1e-10 40.8 0.0 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFH47243.1 - 2.6e-11 44.0 0.0 4.6e-10 39.9 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFH47243.1 - 3e-10 39.8 0.0 9.1e-10 38.3 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit DUF4254 PF14063.1 KFH47243.1 - 0.035 13.7 0.1 0.072 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) Hydrolase_3 PF08282.7 KFH47243.1 - 0.076 12.5 0.0 0.2 11.2 0.0 1.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HLH PF00010.21 KFH47244.1 - 1.1e-10 40.9 0.0 4e-10 39.2 0.0 2.0 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DEAD PF00270.24 KFH47246.1 - 6.9e-22 77.7 0.0 3.8e-21 75.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KFH47246.1 - 1.4e-20 73.9 0.0 2.7e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KFH47246.1 - 2.7e-19 68.7 0.2 6.2e-19 67.6 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KFH47246.1 - 0.0017 18.5 0.0 0.0064 16.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain ATP-grasp_2 PF08442.5 KFH47246.1 - 0.074 12.4 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain zf-C2H2_4 PF13894.1 KFH47248.1 - 0.077 13.3 21.3 0.19 12.1 2.2 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KFH47248.1 - 6.4 7.3 17.8 0.12 12.8 3.3 3.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type TFIIB PF00382.14 KFH47249.1 - 5.5e-31 106.2 0.0 1.1e-19 69.9 0.0 2.8 3 0 0 3 3 3 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 KFH47249.1 - 4.6e-11 41.8 3.2 7.7e-11 41.1 2.2 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 KFH47249.1 - 0.017 15.0 0.0 3.5 7.5 0.0 2.8 1 1 2 3 3 3 0 Cyclin, C-terminal domain RB_B PF01857.15 KFH47249.1 - 0.052 13.0 0.2 0.092 12.2 0.1 1.4 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain Trm112p PF03966.11 KFH47249.1 - 0.12 12.7 0.6 0.43 10.9 0.4 2.2 1 1 0 1 1 1 0 Trm112p-like protein Cyclin_N PF00134.18 KFH47249.1 - 0.29 10.7 0.1 0.29 10.7 0.0 1.7 2 0 0 2 2 2 0 Cyclin, N-terminal domain DSPn PF14671.1 KFH47251.1 - 1.8e-43 147.8 0.0 1.3e-40 138.6 0.0 3.1 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 KFH47251.1 - 2.4e-17 62.7 0.0 6.9e-17 61.2 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFH47251.1 - 1.3e-06 27.9 0.0 2.7e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KFH47251.1 - 0.062 13.3 0.3 0.19 11.7 0.0 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate CwfJ_C_2 PF04676.9 KFH47252.1 - 4.9e-25 87.8 0.3 8.8e-25 87.0 0.2 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.10 KFH47252.1 - 2.3e-22 78.9 0.0 5e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Metallophos PF00149.23 KFH47252.1 - 0.094 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Ofd1_CTDD PF10637.4 KFH47253.1 - 7.8e-100 333.4 0.0 1.1e-91 306.6 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 KFH47253.1 - 1.2e-15 57.8 0.0 4.5e-15 55.9 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily AA_permease PF00324.16 KFH47254.1 - 5.7e-141 470.1 31.7 6.7e-141 469.8 22.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFH47254.1 - 3.9e-39 134.4 31.6 5.2e-39 133.9 21.9 1.1 1 0 0 1 1 1 1 Amino acid permease Fungal_trans PF04082.13 KFH47255.1 - 1.6e-19 69.8 0.0 2.6e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH47255.1 - 6.1e-09 35.6 11.1 1.1e-08 34.8 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PMP1_2 PF08114.6 KFH47256.1 - 0.0044 16.4 1.1 0.0082 15.6 0.7 1.3 1 0 0 1 1 1 1 ATPase proteolipid family SNARE_assoc PF09335.6 KFH47256.1 - 0.064 13.4 0.0 0.099 12.8 0.0 1.3 1 0 0 1 1 1 0 SNARE associated Golgi protein Methyltransf_15 PF09445.5 KFH47257.1 - 1.8e-44 151.1 0.0 2.5e-44 150.6 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 KFH47257.1 - 6.9e-07 29.3 0.0 1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH47257.1 - 0.00036 21.0 0.0 0.0005 20.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 KFH47257.1 - 0.00044 19.7 0.0 0.0011 18.4 0.0 1.6 1 1 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.13 KFH47257.1 - 0.00046 19.8 0.0 0.0012 18.4 0.0 1.6 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Met_10 PF02475.11 KFH47257.1 - 0.0019 17.8 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.1 KFH47257.1 - 0.011 15.2 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 KFH47257.1 - 0.058 12.0 0.0 0.071 11.7 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase DNA_methylase PF00145.12 KFH47257.1 - 0.13 11.3 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase zf-DNL PF05180.7 KFH47258.1 - 1.3e-23 82.4 0.2 1.8e-23 82.0 0.1 1.2 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.8 KFH47258.1 - 0.012 15.0 0.2 0.021 14.3 0.1 1.3 1 0 0 1 1 1 0 CSL zinc finger zf-DNA_Pol PF08996.5 KFH47258.1 - 0.087 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger Elf1 PF05129.8 KFH47258.1 - 0.12 12.1 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.2 KFH47258.1 - 3.7 7.4 6.6 28 4.6 4.5 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Tmemb_14 PF03647.8 KFH47260.1 - 1.3e-24 86.4 6.3 1.5e-24 86.2 4.4 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF2416 PF10315.4 KFH47260.1 - 0.066 13.4 0.5 0.13 12.5 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2416) bZIP_1 PF00170.16 KFH47261.1 - 0.042 13.8 8.2 0.23 11.4 5.7 2.1 1 1 0 1 1 1 0 bZIP transcription factor CUE PF02845.11 KFH47262.1 - 1.1e-07 31.2 0.0 1.8e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 CUE domain DUF3697 PF12478.3 KFH47262.1 - 0.0005 19.6 0.0 0.0013 18.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-associated protein 2 UBA PF00627.26 KFH47262.1 - 0.023 14.5 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain DUF1296 PF06972.6 KFH47262.1 - 0.18 11.7 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) Fungal_trans PF04082.13 KFH47263.1 - 1e-20 73.7 3.4 1.5e-20 73.2 2.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH47263.1 - 1.4e-07 31.2 9.3 2.5e-07 30.4 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_C15 PF01470.12 KFH47264.1 - 1.7e-13 50.9 0.0 1.4e-07 31.5 0.0 2.2 2 0 0 2 2 2 2 Pyroglutamyl peptidase RRM_1 PF00076.17 KFH47265.1 - 1.3e-18 66.4 0.2 2.4e-18 65.5 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH47265.1 - 6.2e-14 51.7 0.1 1.1e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH47265.1 - 8.1e-09 35.2 0.2 1.3e-08 34.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Reo_sigmaC PF04582.7 KFH47266.1 - 0.075 12.1 30.3 0.026 13.7 0.6 5.2 3 1 3 6 6 6 0 Reovirus sigma C capsid protein Cpn60_TCP1 PF00118.19 KFH47268.1 - 9.4e-140 466.4 15.7 1.2e-139 466.1 10.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3924 PF13062.1 KFH47268.1 - 0.006 16.4 0.1 0.13 12.2 0.2 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3924) Phage_tail_X PF05489.7 KFH47268.1 - 0.034 13.6 0.0 0.085 12.3 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Protein X DUF3661 PF12400.3 KFH47269.1 - 3.1e-42 143.7 5.6 5e-42 143.0 3.9 1.3 1 0 0 1 1 1 1 Vaculolar membrane protein CENP-B_dimeris PF09026.5 KFH47269.1 - 0.52 10.5 6.0 0.91 9.7 4.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDC45 PF02724.9 KFH47269.1 - 7.7 4.4 6.0 10 4.0 4.2 1.1 1 0 0 1 1 1 0 CDC45-like protein GRASP55_65 PF04495.9 KFH47270.1 - 5e-45 152.8 0.0 1.6e-44 151.2 0.0 1.7 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain Ribosomal_60s PF00428.14 KFH47271.1 - 9.1 6.7 9.3 1.7 9.1 3.6 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein TAP_C PF03943.8 KFH47272.1 - 1.8e-14 52.8 0.1 3.6e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 KFH47272.1 - 4.8e-06 26.0 0.1 0.00064 19.2 0.0 2.7 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) NTF2 PF02136.15 KFH47272.1 - 0.00012 22.4 0.1 0.0042 17.4 0.0 2.6 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_1 PF00560.28 KFH47272.1 - 0.014 15.2 0.0 9 6.7 0.0 3.3 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_8 PF13855.1 KFH47272.1 - 0.022 14.4 0.0 0.31 10.8 0.0 2.5 1 1 1 2 2 2 0 Leucine rich repeat PH PF00169.24 KFH47273.1 - 4.3e-05 23.6 0.0 9.9e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.12 KFH47273.1 - 0.00013 21.7 0.0 0.00025 20.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFH47273.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) BNR_2 PF13088.1 KFH47274.1 - 1.1e-06 28.1 4.1 0.032 13.5 0.1 5.6 5 2 0 5 5 5 3 BNR repeat-like domain BNR PF02012.15 KFH47274.1 - 2.3e-06 26.5 38.9 2.1 8.5 0.4 11.6 11 0 0 11 11 11 6 BNR/Asp-box repeat DUF2561 PF10812.3 KFH47274.1 - 0.0022 17.6 0.0 0.0041 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2561) Pkinase PF00069.20 KFH47275.1 - 1.1e-07 31.2 0.3 3.6e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH47275.1 - 6.6e-06 25.3 0.2 7.5e-05 21.9 0.0 2.4 3 0 0 3 3 3 1 Protein tyrosine kinase Abhydrolase_6 PF12697.2 KFH47276.1 - 2.9e-21 76.3 2.4 4.6e-21 75.7 1.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH47276.1 - 3.1e-10 39.9 0.2 4.9e-10 39.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFH47276.1 - 0.00034 20.2 0.0 0.006 16.1 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 KFH47276.1 - 0.0097 15.5 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 KFH47276.1 - 0.036 13.6 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_4 PF08386.5 KFH47276.1 - 0.088 12.7 0.1 0.75 9.7 0.0 2.2 2 0 0 2 2 2 0 TAP-like protein Hydrolase_4 PF12146.3 KFH47276.1 - 0.091 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Peptidase_M28 PF04389.12 KFH47277.1 - 2.6e-33 115.2 0.1 1.3e-32 113.0 0.0 1.9 2 1 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 KFH47277.1 - 1.9e-07 30.7 0.1 5.5e-07 29.2 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 YlqD PF11068.3 KFH47278.1 - 0.003 17.5 3.2 0.0037 17.3 2.3 1.2 1 0 0 1 1 1 1 YlqD protein DUF773 PF05600.7 KFH47278.1 - 0.014 14.2 3.7 0.03 13.1 2.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF773) V-ATPase_G PF03179.10 KFH47278.1 - 0.023 14.9 11.0 0.043 14.1 7.6 1.5 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Blt1 PF12754.2 KFH47278.1 - 0.026 14.1 0.6 0.034 13.7 0.4 1.2 1 0 0 1 1 1 0 Cell-cycle control medial ring component Prominin PF05478.6 KFH47278.1 - 0.063 10.8 1.7 0.073 10.5 1.2 1.0 1 0 0 1 1 1 0 Prominin SnoaL PF07366.7 KFH47278.1 - 0.074 12.6 0.1 0.12 11.9 0.1 1.6 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase Metal_resist PF13801.1 KFH47278.1 - 0.11 12.5 6.3 1.2 9.0 4.4 2.0 1 1 0 1 1 1 0 Heavy-metal resistance MatP PF06303.7 KFH47278.1 - 0.11 12.3 5.0 0.13 12.1 3.4 1.1 1 0 0 1 1 1 0 Organiser of macrodomain of Terminus of chromosome DUF1018 PF06252.7 KFH47278.1 - 0.14 12.6 3.6 0.36 11.3 2.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1018) TMA7 PF09072.5 KFH47278.1 - 0.17 12.3 4.8 7.5 7.0 0.5 2.4 1 1 1 2 2 2 0 Translation machinery associated TMA7 SPX PF03105.14 KFH47278.1 - 0.58 9.8 3.8 0.64 9.7 2.7 1.1 1 0 0 1 1 1 0 SPX domain TMF_DNA_bd PF12329.3 KFH47278.1 - 0.59 9.9 5.9 0.36 10.6 0.3 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding ATP-synt_B PF00430.13 KFH47278.1 - 0.68 9.7 12.2 1.1 9.0 8.5 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) ALMT PF11744.3 KFH47278.1 - 1.6 7.3 4.0 1.8 7.1 2.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF1515 PF07439.6 KFH47278.1 - 1.9 8.3 7.8 2.6 7.9 5.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) DUF262 PF03235.9 KFH47278.1 - 2.2 8.1 4.9 30 4.4 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF262 RRM_5 PF13893.1 KFH47279.1 - 5.4e-12 45.3 0.0 7.7e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFH47279.1 - 3.2e-09 36.2 0.0 8.5e-09 34.9 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH47279.1 - 9e-07 28.7 0.0 1.8e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 KFH47279.1 - 9.3e-06 25.3 0.0 1.6e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Calcipressin Limkain-b1 PF11608.3 KFH47279.1 - 0.00027 20.6 0.0 0.0006 19.5 0.0 1.5 1 0 0 1 1 1 1 Limkain b1 Dopey_N PF04118.9 KFH47280.1 - 1.3e-113 378.8 0.0 2.8e-113 377.7 0.0 1.5 1 0 0 1 1 1 1 Dopey, N-terminal HEAT_EZ PF13513.1 KFH47280.1 - 0.0041 17.5 3.3 7.5 7.1 0.0 5.4 4 0 0 4 4 4 1 HEAT-like repeat Sod_Cu PF00080.15 KFH47281.1 - 1.4e-12 47.9 0.0 2.1e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Trypan_PARP PF05887.6 KFH47281.1 - 0.19 11.5 9.9 0.42 10.4 6.8 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Cytochrom_C1 PF02167.10 KFH47282.1 - 1.3e-82 276.7 0.0 1.6e-82 276.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 KFH47282.1 - 0.003 17.6 0.0 0.006 16.6 0.0 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 KFH47282.1 - 0.097 13.5 0.6 0.25 12.1 0.1 2.0 2 1 0 2 2 2 0 Cytochrome c Cytochrom_C550 PF14495.1 KFH47282.1 - 0.11 11.9 0.4 2.2 7.7 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c-550 domain DapB_C PF05173.9 KFH47283.1 - 0.07 12.8 0.0 0.18 11.5 0.0 1.6 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, C-terminus Methyltransf_31 PF13847.1 KFH47284.1 - 3.5e-30 104.5 0.0 4.6e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH47284.1 - 3.2e-15 56.4 0.0 5.5e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFH47284.1 - 1.9e-14 53.8 0.0 3.1e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFH47284.1 - 2.4e-13 49.7 0.2 4.5e-13 48.8 0.1 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KFH47284.1 - 1.8e-12 47.8 0.1 2.9e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH47284.1 - 6.1e-12 45.5 0.0 9e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFH47284.1 - 5.5e-10 39.2 0.0 9e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH47284.1 - 1e-09 38.7 0.0 1.5e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KFH47284.1 - 3.4e-06 26.7 0.1 5.8e-06 25.9 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 KFH47284.1 - 9.5e-06 24.8 0.0 1.3e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 KFH47284.1 - 2.4e-05 23.8 0.0 3.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 KFH47284.1 - 0.00017 21.2 0.0 0.00031 20.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 KFH47284.1 - 0.001 18.1 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase PrmA PF06325.8 KFH47284.1 - 0.0011 18.2 0.1 0.0016 17.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 KFH47284.1 - 0.0026 16.8 0.0 0.0039 16.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase TehB PF03848.9 KFH47284.1 - 0.0031 16.7 0.0 0.0059 15.7 0.0 1.5 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_19 PF04672.7 KFH47284.1 - 0.0039 16.4 0.0 0.0061 15.8 0.0 1.3 1 0 0 1 1 1 1 S-adenosyl methyltransferase DOT1 PF08123.8 KFH47284.1 - 0.0043 16.3 0.0 0.0072 15.6 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 FtsJ PF01728.14 KFH47284.1 - 0.0084 16.1 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase GidB PF02527.10 KFH47284.1 - 0.0095 15.0 0.1 0.018 14.2 0.1 1.4 1 1 0 1 1 1 1 rRNA small subunit methyltransferase G ADH_zinc_N PF00107.21 KFH47284.1 - 0.045 13.2 0.4 0.75 9.3 0.1 2.8 1 1 1 2 2 2 0 Zinc-binding dehydrogenase GCD14 PF08704.5 KFH47284.1 - 0.064 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Phage_tube PF04985.9 KFH47285.1 - 0.1 12.0 1.1 0.15 11.4 0.7 1.2 1 0 0 1 1 1 0 Phage tail tube protein FII DUF4557 PF15101.1 KFH47285.1 - 0.33 10.7 6.2 0.5 10.1 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF4407 PF14362.1 KFH47285.1 - 1.4 7.7 7.6 1.8 7.4 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) WASH-7_C PF14746.1 KFH47285.1 - 2 7.9 5.8 3.3 7.2 4.0 1.3 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal Glyco_transf_36 PF06165.6 KFH47286.1 - 4.8e-22 77.8 0.0 9.1e-22 76.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 36 Bac_rhamnosid PF05592.6 KFH47286.1 - 7.6e-05 21.1 0.0 0.00016 20.0 0.0 1.5 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 KFH47286.1 - 0.0001 21.1 0.1 0.00016 20.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF608 GT36_AF PF06205.6 KFH47286.1 - 0.01 15.5 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase 36 associated family ASXH PF13919.1 KFH47286.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.6 2 0 0 2 2 2 0 Asx homology domain CFEM PF05730.6 KFH47287.1 - 2.3e-10 40.1 10.7 2.9e-10 39.8 6.3 2.0 2 0 0 2 2 2 1 CFEM domain FAD_binding_4 PF01565.18 KFH47288.1 - 8.9e-20 70.5 0.7 2.1e-19 69.3 0.5 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFH47288.1 - 3.9e-09 36.2 0.0 8e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like F-box-like PF12937.2 KFH47289.1 - 0.00018 21.1 0.2 0.00037 20.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like adh_short_C2 PF13561.1 KFH47290.1 - 1.3e-25 90.6 0.0 1.7e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFH47290.1 - 4.5e-24 85.2 0.0 1.3e-23 83.7 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH47290.1 - 6e-09 35.8 0.1 1.2e-08 34.8 0.0 1.4 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 KFH47290.1 - 0.0002 21.0 0.5 0.00038 20.1 0.4 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KFH47290.1 - 0.0042 16.5 0.0 0.0062 16.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 KFH47290.1 - 0.046 12.8 0.0 0.074 12.1 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) WD40 PF00400.27 KFH47291.1 - 5.7e-22 76.7 10.6 4.6e-07 29.4 0.0 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat Rax2 PF12768.2 KFH47291.1 - 0.0032 16.7 0.0 0.0066 15.6 0.0 1.4 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Gmad1 PF10647.4 KFH47291.1 - 0.063 12.6 1.2 2.2 7.6 0.0 3.0 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain TRP PF06011.7 KFH47292.1 - 7.2e-128 426.8 12.2 9.2e-128 426.5 8.5 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KFH47292.1 - 1.1e-36 126.0 0.2 1.6e-36 125.4 0.1 1.2 1 0 0 1 1 1 1 ML-like domain Shisa PF13908.1 KFH47292.1 - 0.071 13.2 3.7 0.22 11.6 0.0 2.7 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator PMT PF02366.13 KFH47293.1 - 3.6e-80 268.8 17.4 3.6e-80 268.8 12.1 1.5 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KFH47293.1 - 2.9e-21 75.8 4.0 4.4e-21 75.2 1.5 2.0 1 1 1 2 2 2 2 MIR domain AAA PF00004.24 KFH47294.1 - 2.4e-40 137.7 0.0 4.2e-40 137.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFH47294.1 - 5.8e-06 26.4 0.0 0.00061 19.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFH47294.1 - 2.7e-05 23.9 0.1 0.00028 20.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KFH47294.1 - 0.00033 20.7 0.0 0.0016 18.4 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 KFH47294.1 - 0.00038 20.4 0.0 0.0013 18.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KFH47294.1 - 0.0017 17.3 0.0 0.0029 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 KFH47294.1 - 0.0046 17.7 0.1 0.014 16.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KFH47294.1 - 0.0098 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KFH47294.1 - 0.01 15.5 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 KFH47294.1 - 0.016 15.0 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KFH47294.1 - 0.022 14.7 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFH47294.1 - 0.033 14.0 0.0 0.064 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KFH47294.1 - 0.035 14.2 0.0 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_3 PF07726.6 KFH47294.1 - 0.039 13.5 0.0 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KFH47294.1 - 0.072 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.1 KFH47294.1 - 0.085 12.9 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 KFH47294.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 KFH47294.1 - 0.14 11.2 0.0 0.31 10.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KFH47294.1 - 0.15 11.4 0.2 0.48 9.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain Asparaginase PF00710.15 KFH47295.1 - 1.6e-61 207.9 0.0 1.7e-61 207.7 0.0 1.0 1 0 0 1 1 1 1 Asparaginase DUF202 PF02656.10 KFH47296.1 - 0.019 15.1 2.3 0.019 15.1 1.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF202) IncA PF04156.9 KFH47297.1 - 0.03 13.9 2.0 0.042 13.4 1.4 1.1 1 0 0 1 1 1 0 IncA protein Sugarporin_N PF11471.3 KFH47297.1 - 0.031 13.9 0.9 0.048 13.3 0.6 1.3 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension REV PF00424.13 KFH47297.1 - 0.066 13.1 4.7 0.12 12.2 3.3 1.4 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) bZIP_2 PF07716.10 KFH47297.1 - 0.07 12.9 8.0 0.099 12.4 5.5 1.2 1 0 0 1 1 1 0 Basic region leucine zipper RmuC PF02646.11 KFH47297.1 - 0.095 11.5 0.1 0.13 11.1 0.1 1.1 1 0 0 1 1 1 0 RmuC family Atg14 PF10186.4 KFH47297.1 - 0.15 11.0 1.9 0.19 10.6 1.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Pox_A_type_inc PF04508.7 KFH47297.1 - 0.33 10.8 4.3 8.4 6.4 0.4 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Nop53 PF07767.6 KFH47297.1 - 0.46 9.4 5.5 0.62 9.0 3.8 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DivIC PF04977.10 KFH47297.1 - 0.91 9.0 3.3 1.5 8.3 2.3 1.3 1 0 0 1 1 1 0 Septum formation initiator CASP_C PF08172.7 KFH47297.1 - 1.8 7.5 6.2 2.5 7.0 4.3 1.1 1 0 0 1 1 1 0 CASP C terminal DNA_pol_phi PF04931.8 KFH47298.1 - 8.5e-47 159.4 45.2 7.7e-32 109.9 25.4 3.4 2 1 0 2 2 2 2 DNA polymerase phi N36 PF11438.3 KFH47298.1 - 0.024 14.1 0.3 0.1 12.1 0.2 2.0 1 0 0 1 1 1 0 36-mer N-terminal peptide of the N protein (N36) DUF1264 PF06884.6 KFH47298.1 - 0.052 13.0 0.1 0.11 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1264) DUF1676 PF07898.8 KFH47298.1 - 0.13 12.5 7.0 0.44 10.8 4.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) TFIIF_alpha PF05793.7 KFH47298.1 - 3.5 5.8 33.8 7.1 4.8 23.4 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Glycos_transf_3 PF00591.16 KFH47299.1 - 4.4e-62 209.7 0.0 7.2e-62 209.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 KFH47299.1 - 2.7e-10 39.6 0.1 5.1e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Pcc1 PF09341.5 KFH47300.1 - 3.1e-24 84.7 0.6 3.1e-24 84.7 0.4 1.4 2 0 0 2 2 2 1 Transcription factor Pcc1 TSA PF03249.8 KFH47300.1 - 1.5 7.2 8.2 1.7 7.1 5.7 1.1 1 0 0 1 1 1 0 Type specific antigen RRN3 PF05327.6 KFH47301.1 - 8e-157 522.7 0.0 1.1e-156 522.3 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Rhodanese PF00581.15 KFH47302.1 - 2.1e-12 47.3 0.0 4.4e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Glyco_hydro_47 PF01532.15 KFH47305.1 - 3.9e-165 549.9 0.0 4.6e-165 549.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 NAD_binding_10 PF13460.1 KFH47306.1 - 1.5e-12 47.8 0.0 2e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KFH47306.1 - 0.00071 19.3 0.5 0.0065 16.2 0.1 2.2 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 KFH47306.1 - 0.063 12.5 0.1 0.088 12.0 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family DRIM PF07539.7 KFH47307.1 - 4.7e-34 116.8 0.2 2.2e-33 114.6 0.1 2.2 1 0 0 1 1 1 1 Down-regulated in metastasis HEAT PF02985.17 KFH47307.1 - 0.031 14.3 10.4 13 6.1 0.0 8.6 9 1 1 10 10 10 0 HEAT repeat KAR9 PF08580.5 KFH47308.1 - 1.5e-137 459.7 7.1 1.5e-137 459.7 4.9 1.5 2 0 0 2 2 2 1 Yeast cortical protein KAR9 Syntaxin-6_N PF09177.6 KFH47308.1 - 0.074 13.4 10.6 1.3 9.5 0.2 4.6 3 2 1 4 4 4 0 Syntaxin 6, N-terminal Prefoldin_2 PF01920.15 KFH47308.1 - 1.6 8.5 5.0 26 4.6 0.1 3.2 3 0 0 3 3 3 0 Prefoldin subunit MFS_1 PF07690.11 KFH47309.1 - 1.6e-41 142.2 54.3 1.3e-38 132.6 37.8 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KFH47309.1 - 5.2e-10 38.1 10.7 7.3e-10 37.6 7.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HeLo PF14479.1 KFH47311.1 - 3.9e-23 82.3 0.3 4e-22 79.0 0.1 2.2 2 0 0 2 2 2 1 Prion-inhibition and propagation Ribonuc_L-PSP PF01042.16 KFH47312.1 - 5.5e-41 139.1 0.0 6.8e-41 138.8 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP YjgF_endoribonc PF14588.1 KFH47312.1 - 0.12 12.3 0.1 0.3 11.0 0.1 1.7 1 1 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease Acetyltransf_2 PF00797.12 KFH47314.1 - 2.1e-39 135.5 0.0 9.1e-37 126.9 0.0 2.1 1 1 1 2 2 2 2 N-acetyltransferase Peptidase_S8 PF00082.17 KFH47316.1 - 1.1e-40 139.5 6.7 1.6e-40 139.0 4.7 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KFH47316.1 - 8.5e-13 48.6 1.1 5.4e-12 46.1 0.7 2.2 1 1 0 1 1 1 1 Peptidase inhibitor I9 WD40 PF00400.27 KFH47317.1 - 7.9e-28 95.3 8.9 3.5e-12 45.7 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat CLTH PF10607.4 KFH47317.1 - 0.00036 20.2 0.1 0.00058 19.5 0.1 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain PD40 PF07676.7 KFH47317.1 - 0.0021 17.6 0.7 0.27 10.9 0.0 3.5 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Fasciclin PF02469.17 KFH47318.1 - 4e-45 152.9 0.0 4e-27 94.7 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain DUF2823 PF11034.3 KFH47319.1 - 7.2e-32 109.3 10.6 7.9e-32 109.2 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) LEA_4 PF02987.11 KFH47319.1 - 0.44 10.4 10.2 0.77 9.6 3.0 2.5 2 1 0 2 2 2 0 Late embryogenesis abundant protein CAS_CSE1 PF03378.10 KFH47320.1 - 1.8e-163 543.8 0.0 3.9e-163 542.8 0.0 1.6 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 KFH47320.1 - 1.2e-145 484.7 4.5 1.9e-145 484.1 3.1 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 KFH47320.1 - 1.3e-11 44.1 0.3 7e-11 41.8 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 KFH47320.1 - 0.016 15.4 0.2 0.68 10.2 0.0 3.5 3 1 0 3 3 3 0 HEAT repeats Xpo1 PF08389.7 KFH47320.1 - 0.032 14.1 5.4 2.9 7.7 0.0 5.0 5 2 1 6 6 6 0 Exportin 1-like protein DUF2309 PF10070.4 KFH47320.1 - 0.16 10.0 0.0 0.26 9.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) Cyt-b5 PF00173.23 KFH47322.1 - 3.5e-19 68.3 0.2 5.6e-19 67.7 0.1 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Paramyxo_ncap PF00973.14 KFH47322.1 - 0.74 8.4 3.3 0.88 8.1 2.3 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Abhydrolase_6 PF12697.2 KFH47323.1 - 1.3e-24 87.3 0.0 1.5e-24 87.1 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH47323.1 - 7.7e-14 51.6 0.0 1.1e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KFH47323.1 - 0.0084 15.0 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.3 KFH47323.1 - 0.048 13.5 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_8 PF06259.7 KFH47323.1 - 0.068 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Chlorophyllase PF07224.6 KFH47323.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase RWD PF05773.17 KFH47324.1 - 2.3e-22 79.0 0.0 4.3e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 KFH47324.1 - 7.4e-21 73.7 32.2 1.1e-13 50.8 1.6 3.8 3 1 1 4 4 4 3 IBR domain zf-RING_2 PF13639.1 KFH47324.1 - 1.7e-05 24.5 7.4 1.7e-05 24.5 5.2 3.6 2 1 1 3 3 3 2 Ring finger domain zf-RING_5 PF14634.1 KFH47324.1 - 0.00063 19.4 4.8 0.00063 19.4 3.3 4.0 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFH47324.1 - 0.00072 19.5 9.0 0.00072 19.5 6.3 4.1 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFH47324.1 - 0.0053 16.4 4.6 0.0053 16.4 3.2 3.1 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.20 KFH47324.1 - 0.0084 15.7 8.3 0.0084 15.7 5.8 4.0 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 KFH47324.1 - 0.81 9.6 24.1 2.2 8.2 0.3 3.4 3 0 0 3 3 3 0 FYVE zinc finger GDPD PF03009.12 KFH47325.1 - 1.2e-14 54.4 0.0 1.9e-14 53.7 0.0 1.4 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Kelch_3 PF13415.1 KFH47326.1 - 1e-20 73.2 3.5 2e-10 40.5 0.0 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.1 KFH47326.1 - 1.6e-16 59.7 6.6 5.2e-08 32.5 0.0 5.8 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.1 KFH47326.1 - 3.6e-12 45.8 0.7 0.00022 21.2 0.0 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.1 KFH47326.1 - 5.3e-12 45.4 7.0 7.6e-06 25.7 0.3 4.8 3 2 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 KFH47326.1 - 2.7e-11 42.8 0.0 0.00068 19.1 0.0 4.3 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.10 KFH47326.1 - 1.6e-09 37.0 0.0 0.00012 21.6 0.0 4.2 3 1 0 3 3 3 2 Kelch motif BTB PF00651.26 KFH47326.1 - 0.00064 19.6 0.0 0.051 13.5 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain Dehydrin PF00257.14 KFH47327.1 - 0.0076 16.5 11.5 0.011 16.1 8.0 1.2 1 0 0 1 1 1 1 Dehydrin DUF1073 PF06381.6 KFH47327.1 - 0.013 14.0 0.4 0.013 14.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1073) BRF1 PF07741.8 KFH47327.1 - 0.053 13.7 2.5 0.071 13.3 1.7 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF632 PF04782.7 KFH47327.1 - 0.087 11.9 3.1 0.11 11.6 2.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF632) FNIP_N PF14636.1 KFH47327.1 - 0.099 13.1 3.9 0.13 12.7 2.7 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus Tom37_C PF11801.3 KFH47327.1 - 0.26 11.1 4.4 0.3 10.9 3.0 1.1 1 0 0 1 1 1 0 Tom37 C-terminal domain Conotoxin PF02950.12 KFH47327.1 - 0.48 11.2 3.4 0.43 11.4 1.5 1.6 1 1 1 2 2 2 0 Conotoxin RP-C_C PF11800.3 KFH47327.1 - 1 8.9 4.7 1.2 8.7 3.2 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region UreD PF01774.12 KFH47328.1 - 5.1e-56 189.4 0.0 6e-56 189.2 0.0 1.0 1 0 0 1 1 1 1 UreD urease accessory protein DUF2236 PF09995.4 KFH47329.1 - 5.3e-56 189.6 1.4 6.5e-56 189.3 1.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) NDT80_PhoG PF05224.7 KFH47330.1 - 1.5e-36 126.1 0.0 3e-36 125.1 0.0 1.5 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family AhpC-TSA PF00578.16 KFH47331.1 - 2.6e-33 114.3 0.0 3.5e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KFH47331.1 - 5.3e-15 55.2 0.0 7.3e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 KFH47331.1 - 1.7e-12 46.7 0.2 3.2e-12 45.8 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin p450 PF00067.17 KFH47332.1 - 3.3e-43 147.9 0.0 4e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3402 PF11882.3 KFH47333.1 - 3.2e-150 500.7 0.0 4.7e-150 500.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 KFH47333.1 - 1.4e-74 250.6 0.0 2e-74 250.1 0.0 1.2 1 0 0 1 1 1 1 N1221-like protein PfkB PF00294.19 KFH47334.1 - 5.4e-16 58.5 0.0 1.5e-15 57.1 0.0 1.7 1 1 0 1 1 1 1 pfkB family carbohydrate kinase PIG-S PF10510.4 KFH47336.1 - 1.1e-146 489.5 0.0 1.3e-146 489.3 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein TBSV_P22 PF03558.8 KFH47336.1 - 0.085 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 TBSV core protein P21/P22 Rhomboid PF01694.17 KFH47337.1 - 1.6e-33 115.8 9.7 1.6e-33 115.8 6.8 2.1 3 0 0 3 3 3 1 Rhomboid family Corona_S2 PF01601.11 KFH47337.1 - 8.3 4.3 5.9 12 3.8 4.1 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Sulfotransfer_3 PF13469.1 KFH47338.1 - 0.00076 20.4 0.4 0.0027 18.6 0.2 1.9 1 1 0 1 1 1 1 Sulfotransferase family peroxidase PF00141.18 KFH47339.1 - 2.2e-23 82.9 0.0 3.4e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Peroxidase FAD_binding_2 PF00890.19 KFH47340.1 - 2.1e-91 306.8 0.1 2.5e-91 306.6 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KFH47340.1 - 3.5e-07 30.1 0.1 1.5e-06 28.1 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KFH47340.1 - 6.5e-05 22.1 0.0 0.00016 20.8 0.0 1.6 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 KFH47340.1 - 8.2e-05 21.6 0.1 0.00019 20.4 0.1 1.6 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KFH47340.1 - 9.6e-05 21.5 0.0 0.00016 20.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFH47340.1 - 0.00012 21.1 0.9 0.0012 17.7 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFH47340.1 - 0.00017 21.5 0.0 0.0011 18.8 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFH47340.1 - 0.0041 17.1 0.1 0.009 16.0 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFH47340.1 - 0.0056 16.4 0.1 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding HI0933_like PF03486.9 KFH47340.1 - 0.0075 14.7 0.1 0.0075 14.7 0.1 2.4 3 0 0 3 3 3 1 HI0933-like protein Lycopene_cycl PF05834.7 KFH47340.1 - 0.0076 15.2 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 KFH47340.1 - 0.0083 15.2 0.0 0.023 13.8 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase DUF3397 PF11877.3 KFH47341.1 - 0.001 19.0 2.1 0.015 15.2 0.2 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3397) p450 PF00067.17 KFH47342.1 - 7.2e-41 140.1 0.0 8.2e-41 139.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Dynamin_M PF01031.15 KFH47343.1 - 2.2e-104 348.4 0.3 4.4e-104 347.4 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 KFH47343.1 - 5.7e-57 192.1 0.0 1.1e-56 191.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KFH47343.1 - 6.8e-30 102.8 5.0 1.4e-29 101.7 3.5 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KFH47343.1 - 0.00033 20.6 0.2 0.0034 17.3 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KFH47343.1 - 0.0071 16.8 0.0 0.11 13.0 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein adh_short PF00106.20 KFH47344.1 - 1.3e-20 73.9 0.1 2.6e-20 72.9 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH47344.1 - 7.7e-20 71.6 0.0 1.3e-19 70.8 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH47344.1 - 1.3e-08 34.6 0.1 5.1e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 KFH47344.1 - 0.0033 17.5 0.0 0.0054 16.8 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 KFH47344.1 - 0.035 13.0 0.0 0.053 12.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KFH47344.1 - 0.043 13.8 0.1 0.1 12.5 0.0 1.6 2 0 0 2 2 2 0 NADH(P)-binding 3Beta_HSD PF01073.14 KFH47344.1 - 0.061 12.0 0.0 0.088 11.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Diphthamide_syn PF01866.12 KFH47345.1 - 1.3e-46 159.2 0.0 2.1e-46 158.5 0.0 1.3 1 1 0 1 1 1 1 Putative diphthamide synthesis protein NAD_kinase PF01513.16 KFH47346.1 - 1.3e-66 224.3 0.0 1.9e-66 223.7 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DUF2422 PF10337.4 KFH47347.1 - 9.1e-75 252.1 7.2 5.3e-41 140.8 3.7 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF2422) DUF2421 PF10334.4 KFH47347.1 - 3.4e-57 193.7 0.0 1.1e-55 188.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 KFH47347.1 - 4.7e-08 33.0 10.4 4.7e-08 33.0 7.2 2.8 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 KFH47347.1 - 4.1e-05 22.4 3.9 4.1e-05 22.4 2.7 1.7 2 0 0 2 2 2 1 Aluminium activated malate transporter Glyco_hydro_43 PF04616.9 KFH47348.1 - 2.5e-37 128.5 0.6 3.1e-37 128.1 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 p450 PF00067.17 KFH47349.1 - 9.8e-34 116.6 0.0 1.2e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 KFH47350.1 - 3.7e-96 322.4 15.8 4.2e-96 322.2 11.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH47350.1 - 1.5e-27 96.2 25.0 5.4e-22 77.9 2.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AT_hook PF02178.14 KFH47351.1 - 5.7e-07 28.4 54.1 0.0063 16.0 0.9 5.7 5 0 0 5 5 5 5 AT hook motif DUF605 PF04652.11 KFH47351.1 - 5.4 6.3 10.2 6.7 5.9 7.0 1.1 1 0 0 1 1 1 0 Vta1 like MutS_V PF00488.16 KFH47352.1 - 9e-80 267.4 0.1 1.6e-79 266.6 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KFH47352.1 - 7.2e-49 166.3 0.1 1.2e-48 165.6 0.1 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KFH47352.1 - 7.1e-34 116.2 0.2 1.7e-33 114.9 0.1 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 KFH47352.1 - 2.6e-14 53.4 0.0 1.2e-13 51.2 0.0 2.2 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 KFH47352.1 - 5.3e-14 52.1 0.4 1.3e-13 50.8 0.3 1.7 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.1 KFH47352.1 - 0.017 15.4 2.2 0.031 14.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KFH47352.1 - 0.024 14.1 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 KFH47352.1 - 0.079 12.9 2.1 0.14 12.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain HET PF06985.6 KFH47353.1 - 1.4e-18 67.3 0.0 6.5e-15 55.5 0.0 2.3 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF1350 PF07082.6 KFH47353.1 - 0.09 11.8 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1350) zf-C2H2_4 PF13894.1 KFH47354.1 - 3.1e-05 24.0 1.5 6.3e-05 23.0 1.0 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 KFH47354.1 - 5.4e-05 23.2 1.5 0.00012 22.1 1.0 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-CGNR PF11706.3 KFH47354.1 - 0.027 13.9 0.2 0.043 13.3 0.1 1.3 1 0 0 1 1 1 0 CGNR zinc finger Ogr_Delta PF04606.7 KFH47354.1 - 0.19 11.3 1.1 0.68 9.6 0.0 2.0 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-H2C2_2 PF13465.1 KFH47354.1 - 0.57 10.5 4.6 0.22 11.8 0.8 2.0 2 0 0 2 2 2 0 Zinc-finger double domain HA2 PF04408.18 KFH47355.1 - 1.8e-19 69.6 1.5 3.5e-19 68.6 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KFH47355.1 - 1.7e-16 60.0 0.0 3.8e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KFH47355.1 - 8.3e-15 54.4 0.0 3.3e-14 52.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFH47355.1 - 8.3e-10 38.4 0.1 2.7e-09 36.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase RWD PF05773.17 KFH47355.1 - 1.1e-09 38.1 0.1 2.3e-09 37.1 0.1 1.6 1 0 0 1 1 1 1 RWD domain AAA_22 PF13401.1 KFH47355.1 - 7.9e-05 22.8 0.1 0.00024 21.2 0.1 1.8 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KFH47355.1 - 0.00069 18.8 0.2 0.0048 16.0 0.0 2.1 2 0 0 2 2 2 1 KaiC DND1_DSRM PF14709.1 KFH47355.1 - 0.0017 18.6 0.3 0.0079 16.4 0.2 2.2 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_29 PF13555.1 KFH47355.1 - 0.0021 17.5 0.0 0.0053 16.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain UBA PF00627.26 KFH47355.1 - 0.0027 17.5 0.0 0.34 10.8 0.0 3.4 2 0 0 2 2 2 1 UBA/TS-N domain T2SE PF00437.15 KFH47355.1 - 0.0087 14.9 0.0 0.021 13.7 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_25 PF13481.1 KFH47355.1 - 0.013 14.9 0.0 0.035 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KFH47355.1 - 0.014 15.4 0.1 0.11 12.4 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain MTBP_mid PF14919.1 KFH47355.1 - 0.027 13.1 0.0 0.058 12.0 0.0 1.4 1 0 0 1 1 1 0 MDM2-binding AAA_23 PF13476.1 KFH47355.1 - 0.041 14.2 1.0 0.097 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KFH47355.1 - 0.043 13.2 0.2 1.4 8.3 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain Bac_rhodopsin PF01036.13 KFH47357.1 - 1.6e-46 158.4 19.8 2e-46 158.1 13.7 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF3366 PF11846.3 KFH47357.1 - 0.011 15.6 1.5 0.011 15.6 1.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3366) DUF4131 PF13567.1 KFH47357.1 - 0.6 9.4 11.6 0.33 10.3 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) YlaH PF14036.1 KFH47357.1 - 0.88 9.6 7.0 0.79 9.8 1.1 2.8 2 0 0 2 2 2 0 YlaH-like protein SUR7 PF06687.7 KFH47357.1 - 5.6 6.4 11.0 11 5.5 3.1 2.5 1 1 1 2 2 2 0 SUR7/PalI family DNA_pol_E_B PF04042.11 KFH47358.1 - 2.4e-52 177.2 0.0 3.4e-52 176.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B p450 PF00067.17 KFH47359.1 - 1.2e-47 162.5 0.0 1.7e-47 162.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 POT1 PF02765.12 KFH47360.1 - 2.5e-10 40.4 0.0 7e-10 38.9 0.0 1.8 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 MFS_1 PF07690.11 KFH47362.1 - 5.1e-30 104.3 29.9 5.1e-30 104.3 20.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.7 KFH47362.1 - 0.19 11.7 3.3 3.9 7.5 0.0 3.4 3 1 0 3 3 3 0 Poxvirus virion envelope protein A14 MIP-T3 PF10243.4 KFH47363.1 - 1.9 6.8 6.9 1.8 6.9 4.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Sugar_tr PF00083.19 KFH47364.1 - 9.1e-75 251.9 13.6 3.3e-47 161.1 0.5 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KFH47364.1 - 1.9e-29 102.4 15.3 1.8e-17 63.1 4.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFH47364.1 - 0.0042 15.5 0.8 0.0042 15.5 0.6 2.5 2 1 0 2 2 2 1 MFS/sugar transport protein TRI12 PF06609.8 KFH47364.1 - 0.0066 14.7 1.1 0.013 13.7 0.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3384 PF11864.3 KFH47365.1 - 1.4e-97 327.0 0.0 2.2e-97 326.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 KFH47365.1 - 1.4e-57 194.1 0.0 2.2e-57 193.4 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 KFH47365.1 - 4.3e-29 101.6 0.3 7.6e-26 91.0 0.0 2.7 3 0 0 3 3 3 2 Tuberin Aldo_ket_red PF00248.16 KFH47366.1 - 8.2e-52 175.7 0.0 9.7e-52 175.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Myb_DNA-bind_6 PF13921.1 KFH47367.1 - 2.2e-06 27.6 2.0 5.6e-06 26.3 1.4 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KFH47367.1 - 0.063 13.3 0.1 0.16 12.0 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Pectate_lyase_3 PF12708.2 KFH47369.1 - 3.5e-12 46.9 3.1 6.4e-12 46.0 0.5 2.3 2 1 0 2 2 2 1 Pectate lyase superfamily protein Glyco_hydro_28 PF00295.12 KFH47369.1 - 3.8e-10 39.2 0.4 1.9e-09 36.9 0.3 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 ELFV_dehydrog PF00208.16 KFH47370.1 - 4.2e-75 252.4 1.7 1e-73 247.9 1.1 2.0 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 KFH47370.1 - 7.4e-48 161.4 0.0 1.2e-47 160.7 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 KFH47370.1 - 0.15 12.3 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding CENP-I PF07778.6 KFH47371.1 - 3.2e-115 385.2 0.0 4.5e-115 384.7 0.0 1.1 1 0 0 1 1 1 1 Mis6 Las1 PF04031.8 KFH47373.1 - 1.5e-57 193.5 0.0 2.6e-57 192.7 0.0 1.4 1 0 0 1 1 1 1 Las1-like Lactamase_B PF00753.22 KFH47373.1 - 7.3e-15 55.1 1.1 1.2e-11 44.6 0.3 2.4 1 1 1 2 2 2 2 Metallo-beta-lactamase superfamily DUF1236 PF06823.7 KFH47373.1 - 0.16 11.6 0.0 3.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1236) GMC_oxred_N PF00732.14 KFH47374.1 - 1.2e-55 188.7 0.0 2e-55 188.0 0.0 1.4 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFH47374.1 - 4.2e-33 114.6 0.0 1.9e-32 112.5 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.9 KFH47374.1 - 0.00089 19.1 0.1 0.92 9.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFH47374.1 - 0.00093 18.1 0.0 0.43 9.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KFH47374.1 - 0.001 18.0 0.0 0.016 14.1 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFH47374.1 - 0.0024 17.8 0.0 0.008 16.1 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KFH47374.1 - 0.017 15.1 0.1 1.4 8.8 0.0 2.5 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase RepC PF06504.6 KFH47375.1 - 0.055 12.4 0.0 0.06 12.2 0.0 1.0 1 0 0 1 1 1 0 Replication protein C (RepC) CM_1 PF07736.6 KFH47376.1 - 0.1 12.6 0.1 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Chorismate mutase type I DUF605 PF04652.11 KFH47376.1 - 3.1 7.1 15.8 3.9 6.7 11.0 1.1 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 KFH47376.1 - 7.5 4.6 26.0 9.5 4.3 18.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 IF4E PF01652.13 KFH47377.1 - 1.3e-34 119.0 0.0 1.7e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E p450 PF00067.17 KFH47378.1 - 2.6e-65 220.7 0.0 4.1e-65 220.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 EBP PF05241.7 KFH47381.1 - 3.2e-69 231.8 9.8 3.8e-69 231.6 6.8 1.0 1 0 0 1 1 1 1 Emopamil binding protein PA14_2 PF10528.4 KFH47382.1 - 2.8e-19 69.1 0.1 4.3e-19 68.5 0.1 1.3 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.7 KFH47382.1 - 0.002 17.7 0.0 0.0034 17.0 0.0 1.3 1 0 0 1 1 1 1 PA14 domain DIM PF08194.7 KFH47382.1 - 1.1 9.2 5.6 10 6.1 0.3 2.9 2 0 0 2 2 2 0 DIM protein Squash PF00299.13 KFH47382.1 - 3.5 7.5 225.5 0.069 12.9 1.3 22.0 23 0 0 23 23 23 0 Squash family serine protease inhibitor PAP2 PF01569.16 KFH47383.1 - 1.8e-13 50.2 4.3 1.8e-13 50.2 3.0 2.0 1 1 1 2 2 2 1 PAP2 superfamily Claudin_2 PF13903.1 KFH47383.1 - 0.026 14.2 0.5 0.026 14.2 0.4 1.7 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF212 PF02681.9 KFH47383.1 - 0.028 14.1 0.0 0.19 11.4 0.0 2.2 2 0 0 2 2 2 0 Divergent PAP2 family PrgI PF12666.2 KFH47383.1 - 0.1 12.7 1.1 0.37 10.9 0.2 2.2 2 0 0 2 2 2 0 PrgI family protein Glyco_trans_4_4 PF13579.1 KFH47383.1 - 0.47 10.5 10.4 0.06 13.4 4.1 1.8 1 1 1 2 2 2 0 Glycosyl transferase 4-like domain Phage_holin_3 PF05106.7 KFH47383.1 - 2.4 8.2 6.4 0.36 10.8 1.3 1.9 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) DNA_pol_B PF00136.16 KFH47384.1 - 6.4e-141 470.3 1.0 9.1e-141 469.8 0.7 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KFH47384.1 - 1.5e-80 270.5 0.1 2.8e-80 269.6 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KFH47384.1 - 3.7e-23 81.3 6.0 6.8e-23 80.4 3.8 1.8 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 KFH47384.1 - 0.0003 20.6 0.2 0.0016 18.3 0.1 2.2 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 KFH47384.1 - 0.0012 18.3 0.0 0.0028 17.2 0.0 1.5 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_2 PF03175.8 KFH47384.1 - 0.0053 15.4 0.4 0.32 9.5 0.0 2.7 3 0 0 3 3 3 1 DNA polymerase type B, organellar and viral Sugar_tr PF00083.19 KFH47385.1 - 9.3e-83 278.2 18.2 1.1e-82 278.0 12.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH47385.1 - 3.7e-19 68.6 40.5 1e-13 50.7 12.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ARGLU PF15346.1 KFH47387.1 - 0.59 9.8 21.3 1.1 9.0 14.8 1.3 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Mnd1 PF03962.10 KFH47387.1 - 5.1 6.7 9.8 8.8 5.9 6.8 1.3 1 0 0 1 1 1 0 Mnd1 family RNA_pol_Rpc4 PF05132.9 KFH47388.1 - 1.4e-24 86.5 0.0 1.4e-24 86.5 0.0 2.8 3 0 0 3 3 3 1 RNA polymerase III RPC4 Hamartin PF04388.7 KFH47388.1 - 0.14 10.8 3.8 0.27 9.8 2.6 1.4 1 0 0 1 1 1 0 Hamartin protein DUF4603 PF15376.1 KFH47388.1 - 1.9 5.5 7.5 2.6 5.1 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) DUF3712 PF12505.3 KFH47389.1 - 8.8e-27 93.6 0.3 1.6e-26 92.7 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) PBP1_TM PF14812.1 KFH47389.1 - 0.003 17.8 0.0 0.0054 17.0 0.0 1.4 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal TMCO5 PF14992.1 KFH47389.1 - 0.045 12.8 0.0 0.066 12.3 0.0 1.2 1 0 0 1 1 1 0 TMCO5 family NmrA PF05368.8 KFH47390.1 - 4.3e-62 209.4 0.2 5.2e-62 209.1 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFH47390.1 - 1.3e-14 54.6 0.1 1.8e-14 54.1 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KFH47390.1 - 5.3e-05 22.0 0.1 7.5e-05 21.5 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Prenyltrans_1 PF13243.1 KFH47392.1 - 5.8e-06 26.2 0.0 0.023 14.7 0.0 3.1 3 0 0 3 3 3 2 Prenyltransferase-like Prenyltrans_2 PF13249.1 KFH47392.1 - 2.8e-05 24.4 0.0 0.51 10.7 0.0 4.4 4 1 0 4 4 4 2 Prenyltransferase-like Terpene_synth_C PF03936.11 KFH47392.1 - 0.00096 18.4 0.5 0.86 8.7 0.0 3.2 3 1 0 3 3 3 2 Terpene synthase family, metal binding domain Prenyltrans PF00432.16 KFH47392.1 - 0.03 13.8 1.7 0.12 12.0 0.1 2.7 3 0 0 3 3 3 0 Prenyltransferase and squalene oxidase repeat DUF2011 PF09428.5 KFH47393.1 - 3.5e-29 101.3 17.6 5.7e-29 100.6 12.2 1.3 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) CAF-1_p150 PF11600.3 KFH47393.1 - 0.06 12.7 26.0 0.12 11.7 18.0 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal MARVEL PF01284.18 KFH47394.1 - 9e-15 54.7 18.4 1.1e-14 54.4 12.8 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF1964 PF09244.5 KFH47394.1 - 0.1 12.9 0.1 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1964) AMP-binding PF00501.23 KFH47395.1 - 3.9e-72 242.9 0.0 5.4e-72 242.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFH47395.1 - 2.5e-11 44.3 1.7 1.7e-09 38.4 0.1 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain polyprenyl_synt PF00348.12 KFH47396.1 - 5e-57 192.7 0.0 6e-57 192.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase MARVEL PF01284.18 KFH47397.1 - 0.0015 18.3 18.3 0.0037 17.0 12.7 1.6 1 1 1 2 2 2 1 Membrane-associating domain 7TMR-DISM_7TM PF07695.6 KFH47397.1 - 0.036 13.7 12.1 0.12 12.0 4.3 2.1 2 0 0 2 2 2 0 7TM diverse intracellular signalling ABC2_membrane_5 PF13346.1 KFH47397.1 - 0.32 10.2 9.4 0.39 9.9 3.4 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein 7tm_7 PF08395.7 KFH47397.1 - 1.2 8.1 8.4 0.23 10.4 2.9 1.7 2 0 0 2 2 2 0 7tm Chemosensory receptor DUF202 PF02656.10 KFH47397.1 - 8.3 6.7 7.7 3.1e+02 1.6 5.3 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF202) MFS_1 PF07690.11 KFH47398.1 - 6e-23 81.1 32.5 3.7e-22 78.5 16.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2157 PF09925.4 KFH47398.1 - 0.11 12.0 13.3 0.037 13.6 1.8 3.4 2 1 0 3 3 3 0 Predicted membrane protein (DUF2157) Acyl-CoA_dh_1 PF00441.19 KFH47399.1 - 1.6e-28 99.7 0.7 2.2e-28 99.2 0.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFH47399.1 - 1.3e-18 67.6 0.0 3.2e-18 66.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KFH47399.1 - 1.4e-17 62.9 1.1 2.4e-17 62.1 0.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KFH47399.1 - 0.00077 19.7 0.3 0.0015 18.7 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 KFH47399.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal 4HBT_2 PF13279.1 KFH47400.1 - 4.2e-06 27.2 0.0 6.2e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily CENP-S PF15630.1 KFH47401.1 - 2.4e-35 120.5 0.0 3e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 KFH47401.1 - 0.0018 17.6 0.0 0.0025 17.1 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T TFIID-18kDa PF02269.11 KFH47401.1 - 0.0018 18.0 0.0 0.0022 17.7 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 KFH47401.1 - 0.012 15.3 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated DUF2773 PF10971.3 KFH47401.1 - 0.031 14.2 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2773) Histone PF00125.19 KFH47401.1 - 0.12 12.4 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 FAD_binding_3 PF01494.14 KFH47402.1 - 4e-12 45.8 0.1 1.4e-11 44.1 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFH47402.1 - 0.014 14.2 0.5 2.8 6.7 0.0 2.3 2 1 0 2 2 2 0 FAD dependent oxidoreductase Kinesin PF00225.18 KFH47403.1 - 4.5e-113 377.3 0.0 7.7e-113 376.5 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain GAS PF13851.1 KFH47403.1 - 0.016 14.4 8.8 0.03 13.5 6.1 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 KFH47403.1 - 0.053 13.2 12.2 0.11 12.1 8.4 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF2018 PF09442.5 KFH47403.1 - 0.16 12.5 5.9 0.24 11.9 2.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) MLANA PF14991.1 KFH47403.1 - 0.21 11.6 1.5 0.45 10.5 0.1 2.3 2 1 0 2 2 2 0 Protein melan-A AAA_23 PF13476.1 KFH47403.1 - 0.35 11.1 2.1 2.8 8.2 0.8 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 KFH47403.1 - 1.3 8.7 7.8 0.68 9.7 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF87 V_ATPase_I PF01496.14 KFH47403.1 - 4.8 4.9 5.2 7.1 4.3 3.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CoA_transf_3 PF02515.12 KFH47404.1 - 2.4e-53 180.2 0.1 3.6e-53 179.6 0.0 1.3 1 0 0 1 1 1 1 CoA-transferase family III MARVEL PF01284.18 KFH47405.1 - 0.00047 20.0 14.4 0.00081 19.2 9.9 1.5 1 1 0 1 1 1 1 Membrane-associating domain Zip PF02535.17 KFH47405.1 - 0.01 14.8 0.5 0.01 14.8 0.4 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter Ctr PF04145.10 KFH47405.1 - 0.13 12.2 0.1 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 Ctr copper transporter family DUF2946 PF11162.3 KFH47405.1 - 0.13 12.4 1.0 0.21 11.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) PLDc_N PF13396.1 KFH47405.1 - 0.14 11.8 5.7 0.28 10.8 0.2 2.9 2 1 0 2 2 2 0 Phospholipase_D-nuclease N-terminal DUF3149 PF11346.3 KFH47405.1 - 0.66 9.5 0.1 0.66 9.5 0.0 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3149) DUF3493 PF11998.3 KFH47405.1 - 0.99 9.3 4.8 3.2 7.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3493) DUF2085 PF09858.4 KFH47405.1 - 2 8.5 5.2 2.5 8.2 1.2 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2085) Wzy_C PF04932.10 KFH47405.1 - 2.8 7.6 7.5 3.5 7.3 5.1 1.4 1 1 0 1 1 1 0 O-Antigen ligase 7TMR-DISM_7TM PF07695.6 KFH47405.1 - 3.2 7.3 16.3 2.1 7.9 8.2 2.0 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF3687 PF12459.3 KFH47406.1 - 0.061 12.5 0.6 0.086 12.0 0.4 1.2 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein Abhydrolase_6 PF12697.2 KFH47407.1 - 3.4e-10 40.2 4.7 5.9e-10 39.4 3.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH47407.1 - 1.5e-07 31.2 0.0 3.2e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFH47407.1 - 0.091 11.9 0.0 0.23 10.6 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family HIT PF01230.18 KFH47408.1 - 3.3e-15 56.3 0.7 7.2e-15 55.3 0.5 1.5 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KFH47408.1 - 1e-12 48.2 6.7 6.8e-12 45.6 4.6 2.0 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF3336 PF11815.3 KFH47409.1 - 6.6e-40 135.9 1.4 1.2e-39 135.0 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KFH47409.1 - 3.9e-22 79.1 0.0 1e-21 77.8 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase Zn_clus PF00172.13 KFH47411.1 - 1.1e-06 28.4 10.7 1.1e-06 28.4 7.4 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Arm PF00514.18 KFH47412.1 - 1e-90 294.7 14.2 3.9e-13 48.6 0.0 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFH47412.1 - 8.1e-24 83.7 0.1 1.5e-10 41.1 0.0 5.9 1 1 4 5 5 5 4 HEAT repeats IBB PF01749.15 KFH47412.1 - 1.3e-22 79.8 1.6 2.1e-22 79.0 1.1 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 KFH47412.1 - 2.3e-22 78.8 8.4 4.6e-10 39.6 0.0 5.9 5 1 2 7 7 7 4 HEAT-like repeat HEAT PF02985.17 KFH47412.1 - 3.9e-21 73.1 0.2 1.2e-06 28.0 0.0 6.8 6 0 0 6 6 6 4 HEAT repeat Arm_2 PF04826.8 KFH47412.1 - 5.5e-10 38.7 0.0 0.026 13.6 0.0 4.2 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.15 KFH47412.1 - 2.3e-05 22.9 0.0 0.00053 18.4 0.0 2.7 1 1 1 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.3 KFH47412.1 - 0.0004 20.3 0.0 3.3 7.6 0.0 4.3 3 2 1 4 4 4 1 V-ATPase subunit H Proteasom_PSMB PF10508.4 KFH47412.1 - 0.00044 18.6 0.0 0.085 11.1 0.0 2.9 2 1 1 3 3 3 2 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.11 KFH47412.1 - 0.0021 18.3 0.2 1.6 9.3 0.0 3.7 4 0 0 4 4 3 1 PBS lyase HEAT-like repeat RICTOR_V PF14668.1 KFH47412.1 - 0.034 14.0 5.3 1.2 9.1 0.0 4.7 4 2 2 6 6 6 0 Rapamycin-insensitive companion of mTOR, domain 5 Glycos_trans_3N PF02885.12 KFH47412.1 - 0.043 13.4 0.0 19 4.9 0.0 3.4 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain HC2 PF07382.6 KFH47413.1 - 0.0027 17.6 31.3 0.0082 16.0 21.7 1.8 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 SNF PF00209.13 KFH47414.1 - 1.3e-91 307.6 35.9 2.9e-89 299.9 24.9 2.1 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family Asp-B-Hydro_N PF05279.6 KFH47414.1 - 0.74 9.6 1.5 1.2 8.9 1.0 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region 6PGD PF00393.14 KFH47415.1 - 6.5e-130 432.5 0.0 8e-130 432.2 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KFH47415.1 - 2e-50 170.8 0.0 2.9e-50 170.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KFH47415.1 - 0.015 15.3 0.0 0.055 13.5 0.0 2.0 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DNA_pol3_beta PF00712.14 KFH47415.1 - 0.1 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III beta subunit, N-terminal domain STAG PF08514.6 KFH47416.1 - 1.5e-26 92.3 0.3 6.4e-26 90.3 0.2 2.1 1 0 0 1 1 1 1 STAG domain HEAT_2 PF13646.1 KFH47416.1 - 1.9e-05 24.8 1.0 0.00024 21.2 0.0 3.3 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 KFH47416.1 - 0.024 14.6 0.1 22 5.4 0.0 4.6 4 0 0 4 4 4 0 HEAT repeat DUF422 PF04240.7 KFH47416.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF422) Oxidored_FMN PF00724.15 KFH47417.1 - 0.00066 18.7 0.0 0.00066 18.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family GFO_IDH_MocA PF01408.17 KFH47418.1 - 2.9e-15 56.8 0.0 4.5e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 KFH47418.1 - 6e-05 23.4 0.0 0.00012 22.4 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain PBP1_TM PF14812.1 KFH47419.1 - 2.1 8.7 9.6 2.4 8.5 0.6 3.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MFS_1 PF07690.11 KFH47420.1 - 3.8e-31 108.0 47.2 3.8e-31 108.0 32.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KFH47420.1 - 0.025 14.3 6.0 2.2 8.1 0.1 3.7 3 0 0 3 3 3 0 MFS_1 like family Transglut_core PF01841.14 KFH47420.1 - 0.05 13.8 0.1 0.16 12.1 0.0 2.0 1 1 0 1 1 1 0 Transglutaminase-like superfamily MFS_2 PF13347.1 KFH47420.1 - 0.4 9.0 40.6 0.039 12.3 11.6 3.0 2 1 1 3 3 3 0 MFS/sugar transport protein ABC2_membrane PF01061.19 KFH47421.1 - 4.1e-86 287.4 55.8 3.5e-45 153.7 15.6 4.2 4 0 0 4 4 4 3 ABC-2 type transporter PDR_CDR PF06422.7 KFH47421.1 - 2e-36 123.7 0.0 4e-29 100.3 0.0 3.2 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 KFH47421.1 - 2.6e-33 115.1 0.0 4.2e-15 56.2 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.1 KFH47421.1 - 1e-15 57.5 0.0 2.3e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_16 PF13191.1 KFH47421.1 - 2.8e-08 33.9 0.4 3.6e-06 27.0 0.2 2.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 KFH47421.1 - 8e-07 28.6 0.0 0.001 18.5 0.0 2.9 3 0 0 3 3 3 2 AAA domain ABC2_membrane_3 PF12698.2 KFH47421.1 - 1.5e-05 24.2 15.5 1.5e-05 24.2 10.8 4.0 3 1 1 4 4 4 1 ABC-2 family transporter protein AAA_29 PF13555.1 KFH47421.1 - 0.00014 21.3 0.7 0.024 14.1 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KFH47421.1 - 0.00038 20.5 0.0 0.15 12.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KFH47421.1 - 0.00058 19.0 0.0 0.0075 15.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 KFH47421.1 - 0.0011 18.8 0.0 0.34 10.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KFH47421.1 - 0.0015 17.9 0.1 0.051 13.0 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.1 KFH47421.1 - 0.0025 17.8 0.0 0.43 10.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KFH47421.1 - 0.0061 17.3 0.0 1.9 9.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KFH47421.1 - 0.0071 16.0 0.1 2.4 7.7 0.1 2.6 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 KFH47421.1 - 0.016 14.9 0.3 3.7 7.3 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain AAA PF00004.24 KFH47421.1 - 0.023 14.8 0.0 4 7.6 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KFH47421.1 - 0.031 14.5 0.0 2.9 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KFH47421.1 - 0.053 12.9 0.2 6.4 6.1 0.0 2.9 3 0 0 3 3 3 0 AAA-like domain IstB_IS21 PF01695.12 KFH47421.1 - 0.12 11.7 0.1 17 4.7 0.0 2.5 2 1 0 2 2 2 0 IstB-like ATP binding protein UPF0079 PF02367.12 KFH47421.1 - 0.2 11.3 0.1 6.1 6.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 KFH47421.1 - 0.21 11.9 0.0 0.51 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain SKG6 PF08693.5 KFH47422.1 - 2e-05 23.7 2.9 4.6e-05 22.6 2.0 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF2562 PF10814.3 KFH47422.1 - 0.0025 17.7 0.2 0.004 17.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2562) DUF4448 PF14610.1 KFH47422.1 - 0.0064 16.0 0.0 0.009 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Methyltransf_23 PF13489.1 KFH47423.1 - 2.1e-14 53.5 0.0 3.8e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH47423.1 - 4.1e-09 36.8 0.0 5e-08 33.3 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH47423.1 - 1.6e-06 28.4 0.0 1.5e-05 25.3 0.0 2.5 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH47423.1 - 0.00058 19.4 0.0 0.027 14.0 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFH47423.1 - 0.0014 18.9 0.0 0.0063 16.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFH47423.1 - 0.0016 17.5 0.0 0.0047 16.0 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KFH47423.1 - 0.013 16.0 0.0 2.4 8.7 0.0 2.9 2 1 0 2 2 2 0 Methyltransferase domain FAP PF07174.6 KFH47423.1 - 0.11 11.7 13.2 0.18 11.0 9.2 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) GFO_IDH_MocA_C PF02894.12 KFH47424.1 - 1.7e-17 63.2 0.3 4.2e-17 62.0 0.2 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.17 KFH47424.1 - 3.2e-17 63.1 0.0 1.2e-16 61.3 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Methyltransf_25 PF13649.1 KFH47424.1 - 0.047 14.0 0.0 0.27 11.6 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Glyco_hydro_2 PF00703.16 KFH47425.1 - 9.2e-10 38.9 0.1 9.2e-10 38.9 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 KFH47425.1 - 3.1e-06 26.8 0.0 6.7e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KFH47425.1 - 3.1e-05 23.0 0.0 5.4e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Alpha_E2_glycop PF00943.14 KFH47425.1 - 0.043 12.4 0.1 0.079 11.5 0.0 1.3 1 0 0 1 1 1 0 Alphavirus E2 glycoprotein AhpC-TSA PF00578.16 KFH47426.1 - 8.8e-09 35.1 0.0 1.3e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KFH47426.1 - 4.6e-05 22.9 0.0 8.8e-05 22.0 0.0 1.4 1 1 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.1 KFH47426.1 - 0.015 15.4 0.0 0.05 13.7 0.0 1.9 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.1 KFH47426.1 - 0.024 14.1 0.0 5 6.6 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin Saccharop_dh PF03435.13 KFH47427.1 - 4e-111 371.7 0.0 4.9e-111 371.4 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 KFH47427.1 - 2.5e-05 24.3 0.1 5.5e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding Shikimate_DH PF01488.15 KFH47427.1 - 0.035 14.2 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF2325 PF10087.4 KFH47427.1 - 0.1 12.4 0.1 0.44 10.4 0.1 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) UbiA PF01040.13 KFH47428.1 - 1.3e-31 109.7 20.9 1.4e-31 109.6 13.6 1.7 1 1 0 1 1 1 1 UbiA prenyltransferase family FAD_oxidored PF12831.2 KFH47429.1 - 7.3e-105 351.5 0.0 1e-104 350.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 KFH47429.1 - 0.17 10.9 0.1 0.27 10.3 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Abhydrolase_3 PF07859.8 KFH47430.1 - 4.4e-08 32.9 0.1 9.5e-05 22.0 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KFH47430.1 - 4.3e-06 26.7 1.7 6.1e-06 26.2 1.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFH47430.1 - 5.2e-05 22.9 0.0 0.00012 21.6 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFH47430.1 - 0.00011 21.9 0.5 0.00023 20.9 0.3 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KFH47430.1 - 0.0075 16.5 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain DUF2974 PF11187.3 KFH47430.1 - 0.017 14.4 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Peptidase_S9 PF00326.16 KFH47430.1 - 0.037 13.2 0.0 0.079 12.1 0.0 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family DUF3089 PF11288.3 KFH47430.1 - 0.048 12.8 0.0 0.072 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Acetyltransf_1 PF00583.19 KFH47431.1 - 5.6e-07 29.4 0.0 2.1e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KFH47431.1 - 0.00029 20.9 0.0 0.00066 19.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KFH47431.1 - 0.00082 19.4 0.0 0.0031 17.6 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFH47431.1 - 0.043 13.5 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein DUF3749 PF12568.3 KFH47431.1 - 0.11 12.0 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Fungal_trans PF04082.13 KFH47432.1 - 0.0061 15.4 0.0 0.013 14.4 0.0 1.4 1 1 1 2 2 2 1 Fungal specific transcription factor domain Alpha-L-AF_C PF06964.7 KFH47433.1 - 1.7e-32 112.6 0.0 3.9e-32 111.4 0.0 1.6 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus EF-hand_7 PF13499.1 KFH47434.1 - 0.00043 20.3 0.0 0.011 15.7 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KFH47434.1 - 0.00084 19.0 0.1 3.2 7.8 0.0 3.9 4 1 0 4 4 4 2 EF-hand domain EF-hand_9 PF14658.1 KFH47434.1 - 0.0016 18.3 0.0 0.059 13.3 0.0 2.4 2 1 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 KFH47434.1 - 0.019 14.2 1.9 2.8 7.4 0.0 4.2 4 1 0 4 4 4 0 EF hand ABC_tran PF00005.22 KFH47436.1 - 6.2e-15 55.7 0.0 5e-14 52.7 0.0 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KFH47436.1 - 1.1e-09 38.6 0.1 0.00048 20.1 0.3 2.1 1 1 0 2 2 2 2 AAA domain DUF3584 PF12128.3 KFH47436.1 - 0.00047 17.6 0.1 0.00061 17.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_29 PF13555.1 KFH47436.1 - 0.00059 19.3 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 KFH47436.1 - 0.0007 18.7 0.0 0.18 10.7 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain SRP54 PF00448.17 KFH47436.1 - 0.0025 17.2 0.0 0.0037 16.7 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SMC_N PF02463.14 KFH47436.1 - 0.0027 16.9 0.0 1.7 7.8 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KFH47436.1 - 0.0052 16.2 0.1 0.0067 15.8 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.1 KFH47436.1 - 0.0059 16.9 0.0 0.0091 16.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFH47436.1 - 0.0059 17.4 0.4 0.025 15.3 0.2 2.0 1 1 1 2 2 2 1 AAA domain PduV-EutP PF10662.4 KFH47436.1 - 0.013 15.0 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 KFH47436.1 - 0.016 15.1 0.1 0.03 14.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KFH47436.1 - 0.016 14.6 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_10 PF12846.2 KFH47436.1 - 0.019 14.3 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 KFH47436.1 - 0.039 13.9 0.9 0.11 12.4 0.6 1.8 1 1 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 KFH47436.1 - 0.04 13.1 0.0 0.066 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 KFH47436.1 - 0.064 13.4 0.3 0.18 11.9 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KFH47436.1 - 0.065 13.4 0.2 0.22 11.7 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arf PF00025.16 KFH47436.1 - 0.072 12.3 0.4 0.19 10.9 0.3 1.7 1 1 0 1 1 1 0 ADP-ribosylation factor family AAA_13 PF13166.1 KFH47436.1 - 0.13 10.7 0.0 0.17 10.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KFH47436.1 - 0.13 11.8 0.2 0.24 11.0 0.1 1.4 1 0 0 1 1 1 0 NACHT domain cobW PF02492.14 KFH47436.1 - 0.17 11.2 0.2 0.26 10.7 0.1 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SIR2 PF02146.12 KFH47438.1 - 1.2e-55 188.0 0.0 1.8e-55 187.3 0.0 1.3 1 0 0 1 1 1 1 Sir2 family CDC45 PF02724.9 KFH47438.1 - 0.44 8.5 5.6 0.4 8.6 2.9 1.5 1 1 1 2 2 2 0 CDC45-like protein Menin PF05053.8 KFH47438.1 - 2 6.4 11.2 2.8 5.9 7.7 1.1 1 0 0 1 1 1 0 Menin RP-C_C PF11800.3 KFH47438.1 - 4.9 6.7 8.0 7.8 6.1 5.6 1.4 1 1 0 1 1 1 0 Replication protein C C-terminal region DAHP_synth_1 PF00793.15 KFH47439.1 - 4.9e-100 333.6 0.1 6e-100 333.4 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family YIEGIA PF14045.1 KFH47439.1 - 0.016 13.8 0.2 0.027 13.1 0.1 1.2 1 0 0 1 1 1 0 YIEGIA protein Ribosomal_L7Ae PF01248.21 KFH47440.1 - 1.7e-24 85.1 0.0 2e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 2-Hacid_dh_C PF02826.14 KFH47441.1 - 5.2e-55 185.3 0.0 1.1e-54 184.3 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFH47441.1 - 2.6e-36 124.0 0.2 3.6e-36 123.5 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.20 KFH47441.1 - 0.0006 19.2 1.0 0.0012 18.2 0.0 2.0 2 0 0 2 2 2 1 ACT domain AlaDh_PNT_C PF01262.16 KFH47441.1 - 0.0045 16.5 1.0 0.028 13.9 0.4 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 KFH47441.1 - 0.03 14.1 0.6 0.059 13.2 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.1 KFH47441.1 - 0.045 14.0 0.0 0.083 13.2 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain adh_short PF00106.20 KFH47442.1 - 2.8e-28 98.9 0.8 2.8e-28 98.9 0.5 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH47442.1 - 4.5e-19 69.1 0.3 5.6e-19 68.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH47442.1 - 4.9e-12 45.8 0.4 4.9e-12 45.8 0.3 1.4 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 KFH47442.1 - 1.7e-07 31.4 0.5 1.4e-06 28.4 0.3 2.1 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFH47442.1 - 2e-05 24.1 0.1 3e-05 23.5 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP2C_2 PF13672.1 KFH47442.1 - 0.011 15.1 0.5 0.017 14.5 0.3 1.2 1 0 0 1 1 1 0 Protein phosphatase 2C NmrA PF05368.8 KFH47442.1 - 0.017 14.3 0.1 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Saccharop_dh PF03435.13 KFH47442.1 - 0.019 13.9 0.2 0.025 13.5 0.2 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 KFH47442.1 - 0.03 13.2 0.1 0.41 9.5 0.1 2.2 1 1 0 1 1 1 0 Male sterility protein TrkA_N PF02254.13 KFH47442.1 - 0.033 14.2 0.1 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Polysacc_synt_2 PF02719.10 KFH47442.1 - 0.13 11.1 0.1 0.23 10.3 0.1 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1643 PF07799.7 KFH47442.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1643) FYVE_2 PF02318.11 KFH47444.1 - 1 9.2 6.4 0.52 10.2 2.6 1.6 1 1 0 1 1 1 0 FYVE-type zinc finger TF_Zn_Ribbon PF08271.7 KFH47444.1 - 1.2 8.4 5.7 13 5.2 0.1 2.5 2 1 0 2 2 2 0 TFIIB zinc-binding His_biosynth PF00977.16 KFH47445.1 - 4.6e-50 170.0 0.2 2.3e-49 167.7 0.1 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 KFH47445.1 - 1.4e-24 86.6 0.0 2.3e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 KFH47445.1 - 4.3e-08 32.9 0.0 8.1e-06 25.5 0.0 2.3 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 KFH47445.1 - 4.4e-06 26.3 0.0 1.3e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.19 KFH47445.1 - 0.043 13.2 0.0 0.19 11.1 0.0 2.0 2 0 0 2 2 2 0 DJ-1/PfpI family Peptidase_C26 PF07722.8 KFH47445.1 - 0.053 12.9 0.1 0.38 10.1 0.0 2.1 2 0 0 2 2 2 0 Peptidase C26 Dus PF01207.12 KFH47445.1 - 0.14 10.9 0.0 0.51 9.1 0.0 1.8 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) HEAT PF02985.17 KFH47447.1 - 0.0014 18.5 0.1 0.017 15.1 0.0 3.0 2 0 0 2 2 2 1 HEAT repeat HEAT_2 PF13646.1 KFH47447.1 - 0.0089 16.2 7.4 0.023 14.9 1.9 3.9 4 1 1 5 5 5 1 HEAT repeats Arm PF00514.18 KFH47447.1 - 0.039 13.7 0.4 0.31 10.9 0.1 2.7 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat KAP PF05804.7 KFH47447.1 - 0.3 8.9 0.0 0.65 7.8 0.0 1.5 2 0 0 2 2 2 0 Kinesin-associated protein (KAP) HEAT_EZ PF13513.1 KFH47447.1 - 4 8.0 7.6 3.1 8.3 1.4 3.9 3 1 0 3 3 3 0 HEAT-like repeat NUDIX PF00293.23 KFH47448.1 - 4.5e-17 61.9 0.4 6.8e-17 61.3 0.3 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 KFH47448.1 - 0.014 14.7 0.1 0.22 10.9 0.1 2.1 1 1 0 1 1 1 0 NUDIX domain Lactonase PF10282.4 KFH47449.1 - 6.5e-14 51.7 0.0 1.1e-13 50.9 0.0 1.4 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller F-box-like PF12937.2 KFH47451.1 - 0.003 17.2 0.1 0.01 15.5 0.1 1.9 1 0 0 1 1 1 1 F-box-like BPL_N PF09825.4 KFH47452.1 - 2.2e-137 457.7 0.0 2.7e-137 457.4 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 KFH47452.1 - 3.8e-17 62.4 0.0 7.6e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Sugar_tr PF00083.19 KFH47453.1 - 6.5e-74 249.1 21.0 7.5e-74 248.9 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH47453.1 - 1.2e-16 60.4 27.4 1.2e-16 60.4 19.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily COX7a PF02238.10 KFH47453.1 - 0.13 12.0 0.1 0.37 10.5 0.1 1.8 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIa Terpene_synth_C PF03936.11 KFH47455.1 - 2.8e-09 36.6 0.0 6.4e-09 35.4 0.0 1.4 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain Erythro-docking PF09277.6 KFH47455.1 - 0.24 11.1 1.7 1.1 9.0 0.1 2.3 2 0 0 2 2 2 0 Erythronolide synthase, docking Pex14_N PF04695.8 KFH47457.1 - 0.0035 17.3 9.2 0.0035 17.3 6.4 2.1 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Macoilin PF09726.4 KFH47457.1 - 0.021 13.1 3.0 0.023 13.0 2.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Spt20 PF12090.3 KFH47457.1 - 0.064 12.6 3.7 0.11 11.8 2.5 1.3 1 0 0 1 1 1 0 Spt20 family PAT1 PF09770.4 KFH47457.1 - 0.16 10.1 15.2 0.21 9.8 10.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GOLD_2 PF13897.1 KFH47457.1 - 0.19 11.9 1.6 0.36 11.0 1.1 1.4 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking DUF4106 PF13388.1 KFH47457.1 - 1.7 7.5 13.0 2.3 7.0 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Kei1 PF08552.6 KFH47457.1 - 2 8.0 6.7 3.9 7.1 4.6 1.4 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 MSA-2c PF12238.3 KFH47457.1 - 3.4 7.2 9.4 8.4 6.0 6.5 1.6 1 0 0 1 1 1 0 Merozoite surface antigen 2c Ndc1_Nup PF09531.5 KFH47457.1 - 7.3 4.8 8.0 11 4.2 5.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Phage_Gp23 PF10669.4 KFH47458.1 - 1.3 9.1 7.5 0.11 12.6 1.7 1.8 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) SLX9 PF15341.1 KFH47458.1 - 1.3 9.4 8.5 2.3 8.6 5.7 1.5 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 Glyco_hydro_61 PF03443.9 KFH47459.1 - 1.7e-56 191.4 0.3 2.5e-56 190.9 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.4 KFH47459.1 - 0.071 13.1 0.0 0.48 10.5 0.0 2.3 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase SWI-SNF_Ssr4 PF08549.5 KFH47459.1 - 0.11 10.8 0.3 0.12 10.6 0.2 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) AMP-binding PF00501.23 KFH47460.1 - 8.5e-88 294.5 0.0 1.3e-87 293.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 KFH47460.1 - 4.6e-59 199.7 0.0 3.7e-31 108.0 0.0 2.6 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.20 KFH47460.1 - 2.4e-07 30.8 0.0 1.3e-06 28.5 0.0 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KFH47460.1 - 2.5e-07 31.5 0.4 8.3e-06 26.6 0.0 3.6 4 0 0 4 4 4 1 AMP-binding enzyme C-terminal domain LEM PF03020.10 KFH47460.1 - 0.067 12.6 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 LEM domain P5CR_dimer PF14748.1 KFH47461.1 - 1.8e-27 95.4 2.2 3.4e-27 94.5 1.5 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KFH47461.1 - 1.2e-11 44.8 0.0 3.2e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent LRR_8 PF13855.1 KFH47462.1 - 3.9e-14 52.1 5.0 2.8e-08 33.3 0.2 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 KFH47462.1 - 1.4e-10 40.5 1.8 1.9e-08 33.7 1.0 2.7 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFH47462.1 - 5.6e-08 31.7 2.7 0.17 12.0 1.0 4.1 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_7 PF13504.1 KFH47462.1 - 3.1e-05 23.4 9.3 0.47 10.8 0.5 4.4 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 KFH47462.1 - 0.02 14.9 1.6 2.1 8.6 0.5 3.1 2 0 0 2 2 2 0 Leucine Rich repeat Amidase PF01425.16 KFH47463.1 - 8.7e-109 364.2 0.4 1.1e-108 363.9 0.3 1.1 1 0 0 1 1 1 1 Amidase Methyltransf_24 PF13578.1 KFH47464.1 - 1.3e-11 45.2 0.0 2.1e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 KFH47464.1 - 8.1e-06 25.0 0.0 0.00048 19.2 0.0 2.2 1 1 0 1 1 1 1 O-methyltransferase Ribosomal_S27e PF01667.12 KFH47466.1 - 2.2e-28 97.5 7.4 2.7e-28 97.2 5.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 KFH47466.1 - 0.011 15.5 1.4 0.013 15.3 1.0 1.2 1 0 0 1 1 1 0 IBR domain TF_Zn_Ribbon PF08271.7 KFH47466.1 - 0.29 10.4 3.3 0.41 10.0 2.3 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding Grp1_Fun34_YaaH PF01184.14 KFH47467.1 - 1.1e-28 100.0 20.0 1.4e-28 99.6 13.9 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Dicty_CAR PF05462.6 KFH47467.1 - 0.028 13.3 5.1 0.038 12.9 3.5 1.1 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor DUF788 PF05620.6 KFH47467.1 - 0.69 9.7 5.2 11 5.8 1.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF788) DUF4191 PF13829.1 KFH47468.1 - 0.081 12.0 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Pkinase PF00069.20 KFH47469.1 - 2.1e-71 240.1 0.0 3e-71 239.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH47469.1 - 5.6e-46 156.7 0.0 9.6e-46 155.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 KFH47469.1 - 6.2e-18 64.9 0.0 2.1e-17 63.3 0.0 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 KFH47469.1 - 9.9e-08 31.2 0.0 1.5e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFH47469.1 - 0.012 15.3 0.4 0.06 13.0 0.0 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family DSHCT PF08148.7 KFH47469.1 - 0.045 13.0 0.0 0.094 11.9 0.0 1.5 1 0 0 1 1 1 0 DSHCT (NUC185) domain Kdo PF06293.9 KFH47469.1 - 0.073 12.1 0.0 0.19 10.7 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KFH47469.1 - 0.16 10.7 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FHA PF00498.21 KFH47470.1 - 8.3e-18 64.2 0.1 2.5e-17 62.7 0.1 1.9 1 0 0 1 1 1 1 FHA domain Ycf1 PF05758.7 KFH47470.1 - 0.056 11.1 4.7 0.08 10.6 3.3 1.1 1 0 0 1 1 1 0 Ycf1 Fib_alpha PF08702.5 KFH47470.1 - 0.27 11.3 6.5 0.48 10.5 2.6 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.6 KFH47470.1 - 0.29 11.0 1.1 0.72 9.8 0.1 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TBPIP PF07106.8 KFH47470.1 - 3.1 7.3 12.2 0.94 9.0 1.8 2.4 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1297 PF06973.7 KFH47471.1 - 0.042 13.1 0.0 0.062 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1297) SIP1 PF04938.7 KFH47472.1 - 0.004 16.5 0.2 1.2 8.4 0.0 3.3 3 0 0 3 3 3 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Toprim_4 PF13662.1 KFH47472.1 - 0.026 14.5 0.1 0.063 13.2 0.1 1.6 1 0 0 1 1 1 0 Toprim domain FAD_binding_3 PF01494.14 KFH47473.1 - 1.7e-73 247.7 0.0 2.3e-73 247.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFH47473.1 - 8.1e-09 34.8 1.3 0.00056 18.9 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFH47473.1 - 0.00073 19.8 0.0 0.19 12.1 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFH47473.1 - 0.02 14.7 2.4 0.12 12.2 0.0 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFH47473.1 - 0.034 13.2 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.1 KFH47473.1 - 0.04 13.9 1.2 0.5 10.4 0.0 3.0 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KFH47473.1 - 0.051 12.6 0.0 0.52 9.3 0.0 2.2 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 KFH47473.1 - 0.24 9.8 0.1 3.6 5.9 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein adh_short PF00106.20 KFH47474.1 - 6.2e-14 52.2 0.4 1e-13 51.5 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KFH47474.1 - 2.6e-05 23.9 0.0 4.2e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 KR domain IFT57 PF10498.4 KFH47475.1 - 0.13 11.0 0.5 0.17 10.5 0.4 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 NOA36 PF06524.7 KFH47475.1 - 0.36 10.0 1.9 0.54 9.4 1.3 1.2 1 0 0 1 1 1 0 NOA36 protein SSP160 PF06933.6 KFH47476.1 - 5.2 4.9 14.5 7.6 4.3 10.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PRP1_N PF06424.7 KFH47477.1 - 3.7e-50 169.7 7.6 8.2e-50 168.5 5.3 1.6 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 KFH47477.1 - 2.5e-33 111.5 32.5 0.00055 20.3 0.2 14.7 4 3 11 15 15 15 10 Tetratricopeptide repeat TPR_19 PF14559.1 KFH47477.1 - 1.9e-24 85.7 18.5 2.7e-06 27.6 0.1 9.9 6 3 4 10 10 10 6 Tetratricopeptide repeat TPR_16 PF13432.1 KFH47477.1 - 2.1e-23 82.3 17.7 3.2e-05 24.4 0.1 9.3 6 2 4 10 10 10 4 Tetratricopeptide repeat TPR_11 PF13414.1 KFH47477.1 - 1.3e-16 60.0 11.4 0.0015 18.1 0.0 9.3 5 4 4 10 10 10 3 TPR repeat TPR_2 PF07719.12 KFH47477.1 - 7.7e-12 44.1 11.6 0.66 10.0 0.0 10.6 12 1 1 13 13 12 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFH47477.1 - 6.5e-09 35.2 7.5 4.6 7.6 0.0 9.7 10 2 2 12 12 10 1 Tetratricopeptide repeat TPR_15 PF13429.1 KFH47477.1 - 8.3e-07 28.3 20.5 0.0028 16.7 2.8 6.1 2 2 2 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFH47477.1 - 1.3e-06 27.7 0.3 0.21 11.4 0.0 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat NARP1 PF12569.3 KFH47477.1 - 2.3e-06 26.6 4.4 1.6 7.4 0.0 6.1 4 1 1 6 6 6 2 NMDA receptor-regulated protein 1 TPR_1 PF00515.23 KFH47477.1 - 1.1e-05 24.8 0.1 0.44 10.2 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFH47477.1 - 1.4e-05 24.4 2.4 1.6 8.7 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFH47477.1 - 2.9e-05 24.2 6.7 10 6.8 0.0 8.9 10 0 0 10 10 8 0 Tetratricopeptide repeat TPR_12 PF13424.1 KFH47477.1 - 2.9e-05 23.9 6.5 0.76 9.7 0.0 6.5 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFH47477.1 - 5.7e-05 22.8 4.4 0.045 13.6 0.0 5.4 5 1 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 KFH47477.1 - 0.00047 20.2 0.0 8.7 6.5 0.0 5.1 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Suf PF05843.9 KFH47477.1 - 0.0046 16.7 0.8 3.7 7.1 0.0 4.2 4 1 0 4 4 4 1 Suppressor of forked protein (Suf) FAT PF02259.18 KFH47477.1 - 0.0099 14.8 10.0 1.5 7.7 0.1 3.7 4 1 0 4 4 4 2 FAT domain DUF3808 PF10300.4 KFH47477.1 - 0.011 14.2 0.3 3.4 6.1 0.0 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF3808) SPOB_a PF14689.1 KFH47477.1 - 0.03 13.8 0.5 0.14 11.7 0.1 2.4 3 0 0 3 3 1 0 Sensor_kinase_SpoOB-type, alpha-helical domain ChAPs PF09295.5 KFH47477.1 - 0.18 10.5 2.1 1 8.0 0.0 2.7 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_21 PF09976.4 KFH47477.1 - 0.84 9.5 25.8 0.22 11.4 1.1 5.9 5 1 1 6 6 5 0 Tetratricopeptide repeat Dioxygenase_C PF00775.16 KFH47478.1 - 9.8e-50 168.3 0.0 1.3e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KFH47478.1 - 9.9e-14 51.0 0.0 1.5e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 KFH47478.1 - 0.058 13.4 0.0 0.32 11.0 0.0 2.1 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Thiolase_N PF00108.18 KFH47479.1 - 1.5e-81 273.2 4.2 2.2e-81 272.7 2.9 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KFH47479.1 - 7.5e-42 141.6 0.1 1.9e-41 140.3 0.1 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 KFH47479.1 - 0.0073 16.3 0.0 0.022 14.7 0.0 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.21 KFH47479.1 - 0.009 15.5 1.7 0.075 12.4 0.6 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Sulfotransfer_3 PF13469.1 KFH47480.1 - 0.042 14.7 1.7 0.072 14.0 1.2 1.7 1 1 0 1 1 1 0 Sulfotransferase family Vac7 PF12751.2 KFH47481.1 - 3.3e-122 408.1 4.0 3.3e-122 408.1 2.8 2.4 2 0 0 2 2 2 1 Vacuolar segregation subunit 7 Cu-oxidase_3 PF07732.10 KFH47482.1 - 1.6e-44 150.3 8.7 2.5e-42 143.3 0.2 3.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KFH47482.1 - 9.4e-36 123.1 0.0 1.3e-34 119.4 0.0 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KFH47482.1 - 2.8e-32 111.0 17.0 3.1e-31 107.7 2.6 3.9 3 1 0 3 3 3 2 Multicopper oxidase Arylsulfotran_2 PF14269.1 KFH47483.1 - 2.1e-53 181.4 1.4 3.1e-53 180.8 1.0 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KFH47483.1 - 5.2e-21 74.7 0.2 1.5e-20 73.2 0.1 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) DUF21 PF01595.15 KFH47484.1 - 1.3e-33 115.7 0.2 2e-33 115.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 KFH47484.1 - 2.4e-09 36.8 1.8 0.00043 20.0 0.1 2.7 2 0 0 2 2 2 2 CBS domain DHDPS PF00701.17 KFH47485.1 - 4.3e-26 91.1 0.0 5.5e-26 90.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF818 PF05677.7 KFH47485.1 - 0.11 11.2 0.1 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Mgm101p PF06420.7 KFH47487.1 - 3e-80 267.5 0.0 4.2e-80 267.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 DUF4614 PF15391.1 KFH47487.1 - 0.05 13.3 8.0 0.097 12.4 5.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) MFS_1 PF07690.11 KFH47488.1 - 3e-17 62.3 34.5 3e-17 62.3 23.9 1.4 1 1 1 2 2 2 1 Major Facilitator Superfamily PBP1_TM PF14812.1 KFH47488.1 - 0.14 12.5 0.8 0.53 10.6 0.0 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal YtpI PF14007.1 KFH47488.1 - 0.99 9.3 5.4 0.94 9.4 1.2 2.7 2 0 0 2 2 2 0 YtpI-like protein Gate PF07670.9 KFH47488.1 - 1.2 9.0 14.6 0.018 14.9 2.3 2.9 2 1 0 2 2 2 0 Nucleoside recognition RPE65 PF03055.10 KFH47490.1 - 6e-119 397.7 0.0 6.9e-119 397.5 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF1664 PF07889.7 KFH47491.1 - 0.0042 16.8 4.4 0.0042 16.8 3.0 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF1664) IncA PF04156.9 KFH47491.1 - 0.0074 15.9 13.9 0.0074 15.9 9.6 3.3 3 0 0 3 3 3 1 IncA protein Bacillus_HBL PF05791.6 KFH47491.1 - 0.21 10.9 8.2 0.59 9.4 5.7 1.8 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) UPF0278 PF08745.6 KFH47491.1 - 0.35 10.0 4.8 0.19 10.9 1.7 1.7 1 1 1 2 2 2 0 UPF0278 family DUF3450 PF11932.3 KFH47491.1 - 1 8.5 17.6 7.1 5.8 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) Transposase_22 PF02994.9 KFH47491.1 - 1.5 7.1 25.2 0.26 9.7 13.3 2.2 1 1 1 2 2 2 0 L1 transposable element DUF4200 PF13863.1 KFH47491.1 - 1.6 8.6 42.9 0.59 10.0 5.8 4.2 4 1 0 4 4 4 0 Domain of unknown function (DUF4200) Fib_alpha PF08702.5 KFH47491.1 - 1.8 8.6 18.0 3 7.9 4.4 3.3 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family DUF342 PF03961.8 KFH47491.1 - 3.3 6.0 13.6 0.4 9.0 6.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF342) LMBR1 PF04791.11 KFH47491.1 - 3.7 6.0 7.8 5 5.5 5.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein V_ATPase_I PF01496.14 KFH47491.1 - 5.4 4.7 16.4 0.56 7.9 8.2 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family ERM PF00769.14 KFH47491.1 - 7.8 5.9 38.3 11 5.4 19.7 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family ODC_AZ PF02100.12 KFH47492.1 - 1.5e-27 95.2 0.0 2.5e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Peptidase_C14 PF00656.17 KFH47493.1 - 3.7e-71 239.7 0.0 4.5e-71 239.4 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Meth_synt_2 PF01717.13 KFH47494.1 - 8.9e-21 74.1 0.0 1.1e-15 57.4 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KFH47494.1 - 1.7e-06 27.5 0.0 0.0053 16.0 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain Yip1 PF04893.12 KFH47496.1 - 0.034 13.6 1.0 0.16 11.4 0.7 1.8 1 1 0 1 1 1 0 Yip1 domain Rtf2 PF04641.7 KFH47496.1 - 0.077 12.1 0.2 0.095 11.8 0.1 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger FlxA PF14282.1 KFH47497.1 - 0.065 13.1 0.7 0.15 12.0 0.5 1.6 1 0 0 1 1 1 0 FlxA-like protein TMF_DNA_bd PF12329.3 KFH47497.1 - 0.28 11.0 0.1 0.96 9.2 0.0 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ARID PF01388.16 KFH47498.1 - 7.6e-17 60.9 0.0 1.7e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain SEN1_N PF12726.2 KFH47498.1 - 0.16 10.0 0.1 0.21 9.5 0.0 1.1 1 0 0 1 1 1 0 SEN1 N terminal CBFD_NFYB_HMF PF00808.18 KFH47499.1 - 3.5e-17 62.2 0.2 5.6e-17 61.5 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFH47499.1 - 0.00037 20.5 0.0 0.0011 18.9 0.0 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIIS_C PF01096.13 KFH47500.1 - 0.24 11.0 1.1 0.91 9.2 0.1 2.1 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) YadA_anchor PF03895.10 KFH47500.1 - 0.81 9.7 5.9 1.1 9.3 4.1 1.2 1 0 0 1 1 1 0 YadA-like C-terminal region Methyltransf_23 PF13489.1 KFH47501.1 - 9.7e-14 51.4 0.1 2e-13 50.3 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH47501.1 - 2.8e-08 34.1 0.0 4.8e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH47501.1 - 3.9e-07 30.4 0.0 2.8e-06 27.7 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH47501.1 - 1.7e-05 24.4 0.0 3.8e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFH47501.1 - 0.00024 20.3 0.0 0.00052 19.1 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KFH47501.1 - 0.0018 18.8 0.0 0.0046 17.5 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFH47501.1 - 0.051 13.9 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Fe-ADH_2 PF13685.1 KFH47501.1 - 0.077 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase Ribosomal_L16 PF00252.13 KFH47502.1 - 1.7e-31 108.7 0.0 2.1e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Glyoxalase PF00903.20 KFH47503.1 - 3.8e-37 127.1 0.1 1.6e-17 63.7 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KFH47503.1 - 1.8e-29 102.4 0.0 3.8e-14 53.2 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KFH47503.1 - 1.6e-15 57.0 0.0 2.4e-07 30.7 0.0 3.6 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 KFH47503.1 - 0.0022 17.9 0.0 1.1 9.1 0.0 2.6 2 1 1 3 3 3 2 Glyoxalase-like domain MoaF PF10703.4 KFH47503.1 - 0.098 11.7 0.0 2.2 7.2 0.0 2.1 2 0 0 2 2 2 0 Molybdenum cofactor biosynthesis protein F DUF946 PF06101.6 KFH47504.1 - 4.3e-12 44.8 0.1 7.8e-12 43.9 0.1 1.3 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) DUF500 PF04366.7 KFH47505.1 - 2.1e-43 146.7 0.5 3.7e-43 145.9 0.1 1.5 2 0 0 2 2 2 1 Family of unknown function (DUF500) SH3_1 PF00018.23 KFH47505.1 - 1e-14 53.6 0.2 4.9e-14 51.4 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KFH47505.1 - 1.5e-13 50.0 0.0 3e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFH47505.1 - 1e-11 44.1 0.0 2.2e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF2523 PF10734.4 KFH47506.1 - 0.08 13.1 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2523) COX14 PF14880.1 KFH47507.1 - 2.1e-14 52.8 0.2 2.1e-14 52.8 0.2 1.8 2 0 0 2 2 2 1 Cytochrome oxidase c assembly PRP4 PF08799.6 KFH47507.1 - 0.029 13.6 0.3 0.057 12.7 0.2 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like DUF3735 PF12537.3 KFH47507.1 - 0.38 10.8 0.1 0.38 10.8 0.0 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3735) ArfGap PF01412.13 KFH47508.1 - 1.3e-40 137.7 0.4 2e-40 137.2 0.3 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Pex24p PF06398.6 KFH47509.1 - 6.1e-101 337.7 0.0 8.6e-101 337.2 0.0 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Pam16 PF03656.8 KFH47510.1 - 7.5e-30 103.3 0.1 9.6e-30 102.9 0.1 1.1 1 0 0 1 1 1 1 Pam16 DUF1110 PF06533.7 KFH47510.1 - 0.1 12.3 0.1 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1110) DUF2236 PF09995.4 KFH47512.1 - 1.2e-26 93.4 0.1 1.8e-26 92.9 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF997 PF06196.7 KFH47512.1 - 0.1 12.1 1.3 5.5 6.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF997) WWbp PF10349.4 KFH47514.1 - 2.8e-16 60.4 3.3 5.1e-16 59.6 2.3 1.4 1 0 0 1 1 1 1 WW-domain ligand protein Vps36_ESCRT-II PF11605.3 KFH47514.1 - 0.0055 16.4 0.0 0.019 14.7 0.0 1.8 1 1 1 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 KFH47514.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 GRAM domain PSII_Pbs27 PF13326.1 KFH47515.1 - 0.042 13.8 0.7 0.069 13.1 0.5 1.4 1 0 0 1 1 1 0 Photosystem II Pbs27 CHCH PF06747.8 KFH47516.1 - 0.00014 21.7 11.6 0.00021 21.1 8.0 1.3 1 0 0 1 1 1 1 CHCH domain COX17 PF05051.8 KFH47516.1 - 0.004 17.1 3.3 0.006 16.5 2.3 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 KFH47516.1 - 0.074 12.8 8.2 0.53 10.0 5.7 2.0 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like PRP38 PF03371.10 KFH47518.1 - 9.2e-65 217.4 0.0 1.1e-64 217.1 0.0 1.1 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.2 KFH47518.1 - 0.18 12.3 11.2 0.36 11.3 7.8 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term BSP_II PF05432.6 KFH47518.1 - 3.3 6.9 13.6 4.7 6.4 9.5 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) ketoacyl-synt PF00109.21 KFH47519.1 - 1.1e-64 218.3 0.6 1.1e-64 218.3 0.4 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KFH47519.1 - 7.2e-52 176.6 3.8 1e-51 176.1 2.7 1.2 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KFH47519.1 - 4.5e-50 169.8 0.0 3e-49 167.1 0.0 2.3 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KFH47519.1 - 6.9e-42 143.1 0.6 2.2e-41 141.5 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 KFH47519.1 - 7.2e-42 143.5 0.0 2.2e-39 135.3 0.0 2.3 2 0 0 2 2 2 2 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KFH47519.1 - 7.8e-24 83.8 0.0 3.6e-23 81.6 0.0 2.3 1 1 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KFH47519.1 - 2.9e-18 65.6 0.1 1.7e-17 63.2 0.0 2.4 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KFH47519.1 - 3e-18 66.1 0.0 1.5e-17 63.8 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH47519.1 - 1.8e-11 44.0 0.2 6e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 KFH47519.1 - 3.6e-10 39.9 0.0 1.2e-09 38.3 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.1 KFH47519.1 - 1.4e-09 37.6 0.0 3.7e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH47519.1 - 1.6e-09 38.3 0.0 8.9e-09 35.9 0.0 2.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KFH47519.1 - 1.8e-09 38.5 0.0 1.8e-08 35.3 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFH47519.1 - 1.6e-08 34.2 0.0 3.7e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.7 KFH47519.1 - 3e-07 30.8 0.0 1.9e-06 28.2 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.4 KFH47519.1 - 0.0003 20.3 0.0 0.00064 19.2 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Thiolase_N PF00108.18 KFH47519.1 - 0.0011 18.0 0.1 0.002 17.1 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.10 KFH47519.1 - 0.0089 14.9 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Ubie_methyltran PF01209.13 KFH47519.1 - 0.011 14.8 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DREV PF05219.7 KFH47519.1 - 0.027 13.3 0.0 0.052 12.4 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase NodS PF05401.6 KFH47519.1 - 0.12 11.7 0.0 0.31 10.3 0.0 1.6 1 0 0 1 1 1 0 Nodulation protein S (NodS) TFIIIC_sub6 PF10419.4 KFH47521.1 - 6.4e-13 47.9 0.0 1.1e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit RTC PF01137.16 KFH47522.1 - 1e-38 132.3 0.0 4.5e-38 130.2 0.0 1.9 2 1 0 2 2 2 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 KFH47522.1 - 0.0055 16.7 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Pyr_redox_3 PF13738.1 KFH47523.1 - 1.8e-24 86.9 0.1 9.7e-23 81.2 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFH47523.1 - 1.4e-10 41.4 0.0 1.9e-07 31.1 0.0 2.9 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFH47523.1 - 6.2e-10 38.5 0.1 4.3e-07 29.1 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 KFH47523.1 - 3.8e-08 31.9 0.0 2.8e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KFH47523.1 - 2.2e-06 27.5 0.0 2.3e-05 24.3 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KFH47523.1 - 4.3e-05 22.5 0.2 0.0038 16.1 0.1 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KFH47523.1 - 5.7e-05 22.3 0.0 0.00039 19.5 0.0 2.2 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.19 KFH47523.1 - 0.00018 20.5 0.2 0.13 11.0 0.0 3.1 2 1 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KFH47523.1 - 0.0002 19.9 0.1 0.0026 16.3 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 KFH47523.1 - 0.00023 20.1 0.0 0.0015 17.4 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 KFH47523.1 - 0.0003 21.1 0.1 0.83 10.0 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KFH47523.1 - 0.00032 20.3 0.1 0.85 9.2 0.0 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 KFH47523.1 - 0.002 17.8 0.2 1.4 8.6 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 KFH47523.1 - 0.005 16.4 0.0 0.0093 15.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 KFH47523.1 - 0.0069 15.5 0.2 0.052 12.6 0.0 2.3 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KFH47523.1 - 0.015 15.3 0.1 5.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 KFH47523.1 - 0.017 14.2 0.0 0.063 12.3 0.0 1.9 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.13 KFH47523.1 - 0.023 14.6 0.0 0.15 12.1 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_7 PF13241.1 KFH47523.1 - 0.061 13.5 0.0 7.9 6.7 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding SnoaL_2 PF12680.2 KFH47523.1 - 0.44 10.9 5.1 0.25 11.7 0.1 2.7 3 0 0 3 3 2 0 SnoaL-like domain SelR PF01641.13 KFH47524.1 - 6.6e-47 158.2 0.0 9.7e-47 157.7 0.0 1.2 1 0 0 1 1 1 1 SelR domain DUF2296 PF10058.4 KFH47524.1 - 0.047 13.4 1.4 0.21 11.3 0.0 2.4 3 0 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) zf-Mss51 PF13824.1 KFH47524.1 - 0.065 13.1 2.1 1.3 8.9 0.3 3.0 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 TF_Zn_Ribbon PF08271.7 KFH47524.1 - 0.081 12.2 1.2 0.63 9.4 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding DZR PF12773.2 KFH47524.1 - 0.49 10.2 3.8 10 6.0 2.3 2.4 1 1 1 2 2 2 0 Double zinc ribbon Transferase PF02458.10 KFH47525.1 - 6.5e-09 34.7 0.0 0.0003 19.3 0.0 2.3 3 0 0 3 3 3 2 Transferase family CbiC PF02570.10 KFH47525.1 - 0.059 12.7 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 Precorrin-8X methylmutase IMD PF08397.6 KFH47527.1 - 0.001 18.4 4.2 0.016 14.5 2.9 2.1 1 1 0 1 1 1 1 IRSp53/MIM homology domain Zn_clus PF00172.13 KFH47528.1 - 0.081 12.8 12.9 0.83 9.6 8.9 2.3 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_3 PF13302.1 KFH47529.1 - 8.8e-13 48.6 0.0 1e-12 48.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFH47529.1 - 5.8e-10 39.0 0.1 9.1e-10 38.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KFH47529.1 - 0.007 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 KFH47529.1 - 0.0096 15.8 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFH47529.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain KH_1 PF00013.24 KFH47530.1 - 8.3e-93 304.0 25.4 1e-12 47.4 0.5 14.7 14 2 0 14 14 14 10 KH domain KH_3 PF13014.1 KFH47530.1 - 5.6e-63 207.7 18.6 7.6e-10 38.2 0.2 13.3 14 0 0 14 14 14 8 KH domain KH_2 PF07650.12 KFH47530.1 - 1e-12 47.4 18.8 0.017 14.6 0.0 7.9 6 1 1 7 7 7 4 KH domain SLS PF14611.1 KFH47530.1 - 8.8e-11 41.6 4.1 0.0018 17.7 0.0 6.6 5 1 2 7 7 7 4 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.1 KFH47530.1 - 0.015 14.9 8.3 14 5.4 0.0 5.8 6 0 0 6 6 6 0 KH domain BLUF PF04940.7 KFH47530.1 - 1.9 8.2 4.3 47 3.8 0.2 4.0 4 0 0 4 4 4 0 Sensors of blue-light using FAD APH PF01636.18 KFH47531.1 - 1.3e-06 28.3 0.2 2.2e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Phosducin PF02114.11 KFH47532.1 - 1.2e-16 60.2 0.1 1.6e-16 59.8 0.1 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 KFH47532.1 - 0.027 14.1 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin alpha-hel2 PF14456.1 KFH47532.1 - 0.028 13.2 0.1 0.043 12.5 0.0 1.2 1 0 0 1 1 1 0 Alpha-helical domain 2 Acyl_transf_3 PF01757.17 KFH47533.1 - 2.5e-33 115.3 20.0 1.2e-32 113.1 13.9 2.0 1 1 0 1 1 1 1 Acyltransferase family DUF418 PF04235.7 KFH47533.1 - 0.00011 21.9 2.0 0.00011 21.9 1.4 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF418) COX16 PF14138.1 KFH47534.1 - 6.5e-32 109.5 0.2 8.5e-32 109.1 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 CLN3 PF02487.12 KFH47535.1 - 4.6e-24 84.9 0.4 7.2e-24 84.3 0.2 1.3 1 1 1 2 2 2 1 CLN3 protein MFS_1 PF07690.11 KFH47535.1 - 0.48 9.0 43.3 4.8 5.8 28.5 2.4 1 1 0 1 1 1 0 Major Facilitator Superfamily CbtB PF09489.5 KFH47535.1 - 3 7.8 5.3 10 6.0 0.0 3.8 3 1 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) DUF1049 PF06305.6 KFH47535.1 - 4 6.9 6.3 11 5.5 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) RNR_inhib PF08591.5 KFH47536.1 - 1.1e-21 77.5 0.1 5.2e-21 75.3 0.0 2.1 2 1 0 2 2 2 1 Ribonucleotide reductase inhibitor APH PF01636.18 KFH47537.1 - 0.016 14.9 2.4 0.12 12.0 0.0 2.6 1 1 2 3 3 3 0 Phosphotransferase enzyme family TraE PF05309.6 KFH47537.1 - 0.087 11.9 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 TraE protein Apolipoprotein PF01442.13 KFH47539.1 - 0.064 12.7 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 KFH47539.1 - 1.6 9.1 4.9 2.4 8.6 2.1 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Romo1 PF10247.4 KFH47540.1 - 4.7e-28 97.1 13.8 5.9e-28 96.8 9.6 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Gly-zipper_YMGG PF13441.1 KFH47540.1 - 0.3 10.6 3.0 0.65 9.5 2.1 1.6 1 1 0 1 1 1 0 YMGG-like Gly-zipper Spore_YabQ PF09578.5 KFH47540.1 - 0.68 9.9 3.8 3 7.8 0.5 2.1 2 0 0 2 2 2 0 Spore cortex protein YabQ (Spore_YabQ) Gly-zipper_OmpA PF13436.1 KFH47540.1 - 0.72 9.5 3.8 4.5 6.9 2.6 2.0 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Tim17 PF02466.14 KFH47540.1 - 1.4 8.9 8.4 2.2 8.3 5.7 1.4 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Amidohydro_1 PF01979.15 KFH47541.1 - 4.3e-16 59.4 1.0 5.9e-07 29.4 0.0 2.7 2 1 0 3 3 3 2 Amidohydrolase family Amidohydro_5 PF13594.1 KFH47541.1 - 1.5e-14 53.5 0.4 8.4e-14 51.1 0.1 2.5 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 KFH47541.1 - 1.1e-07 32.2 0.9 0.0039 17.2 0.1 2.5 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 KFH47541.1 - 1.3e-06 27.9 1.7 0.00032 20.0 0.1 2.5 1 1 1 2 2 2 2 Amidohydrolase family Methyltransf_18 PF12847.2 KFH47541.1 - 0.0018 18.8 0.0 0.0046 17.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain OCD_Mu_crystall PF02423.10 KFH47542.1 - 2.6e-17 62.5 0.0 1.4e-12 47.0 0.0 2.9 3 0 0 3 3 3 2 Ornithine cyclodeaminase/mu-crystallin family PYRIN PF02758.11 KFH47542.1 - 0.17 11.6 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 PAAD/DAPIN/Pyrin domain RrnaAD PF00398.15 KFH47543.1 - 3.8e-59 199.8 0.0 5.2e-59 199.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 KFH47543.1 - 2.2e-09 37.3 0.0 4e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH47543.1 - 1.1e-05 25.9 0.0 2.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFH47543.1 - 0.00024 20.5 0.0 0.00039 19.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.13 KFH47543.1 - 0.00044 19.5 0.0 0.00079 18.6 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase CMAS PF02353.15 KFH47543.1 - 0.00092 18.3 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KFH47543.1 - 0.0018 17.9 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KFH47543.1 - 0.0021 17.6 0.0 0.0035 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 KFH47543.1 - 0.0091 15.5 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH47543.1 - 0.012 16.0 0.1 0.039 14.4 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain Bd3614_N PF14442.1 KFH47543.1 - 0.068 13.1 1.1 0.13 12.2 0.8 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal UPF0020 PF01170.13 KFH47543.1 - 0.081 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 TUSC2 PF15000.1 KFH47543.1 - 0.091 12.8 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Tumour suppressor candidate 2 ANAPC15 PF15243.1 KFH47543.1 - 0.26 11.3 4.6 0.49 10.5 3.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Drf_GBD PF06371.8 KFH47546.1 - 1.1e-15 57.5 1.4 8.4e-10 38.3 0.0 2.2 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain TB2_DP1_HVA22 PF03134.14 KFH47548.1 - 4.8e-25 87.1 8.4 7.2e-14 51.2 3.0 2.2 1 1 1 2 2 2 2 TB2/DP1, HVA22 family Lipase_GDSL_2 PF13472.1 KFH47549.1 - 2.5e-15 57.0 4.0 9.3e-15 55.2 2.8 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFH47549.1 - 3.3e-12 46.7 0.4 4.5e-12 46.3 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 KFH47549.1 - 2.5e-06 27.3 0.0 9.2e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family EF-hand_9 PF14658.1 KFH47549.1 - 0.08 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain UCR_hinge PF02320.11 KFH47550.1 - 4e-28 97.1 7.3 1.1e-27 95.7 5.0 1.7 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein CDC45 PF02724.9 KFH47550.1 - 0.022 12.8 8.4 0.022 12.7 5.8 1.0 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 KFH47550.1 - 0.21 10.6 14.6 0.24 10.4 10.1 1.0 1 0 0 1 1 1 0 BUD22 DUF1510 PF07423.6 KFH47550.1 - 0.22 10.8 20.0 0.25 10.7 13.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2201_N PF13203.1 KFH47550.1 - 0.37 9.9 5.9 0.46 9.5 4.1 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain GET2 PF08690.5 KFH47550.1 - 0.7 9.0 4.5 0.87 8.7 3.1 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Pox_Ag35 PF03286.9 KFH47550.1 - 0.9 9.0 13.4 1.1 8.7 9.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PLRV_ORF5 PF01690.12 KFH47550.1 - 0.94 8.5 10.4 1 8.4 7.2 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF2052 PF09747.4 KFH47550.1 - 1.3 8.8 17.0 1.9 8.3 11.8 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DDHD PF02862.12 KFH47550.1 - 1.4 8.6 8.3 1.8 8.2 5.8 1.2 1 0 0 1 1 1 0 DDHD domain DUF4045 PF13254.1 KFH47550.1 - 1.8 7.7 10.5 2 7.6 7.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Daxx PF03344.10 KFH47550.1 - 1.9 6.9 25.2 2.1 6.7 17.5 1.1 1 0 0 1 1 1 0 Daxx Family RNA_polI_A34 PF08208.6 KFH47550.1 - 2.5 7.7 14.0 2.9 7.5 9.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 HSP70 PF00012.15 KFH47550.1 - 2.6 5.8 11.9 2.9 5.6 8.2 1.0 1 0 0 1 1 1 0 Hsp70 protein Ycf1 PF05758.7 KFH47550.1 - 2.7 5.6 11.3 2.7 5.5 7.8 1.0 1 0 0 1 1 1 0 Ycf1 Tim54 PF11711.3 KFH47550.1 - 3.2 6.2 14.4 3.6 6.0 10.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 eIF-3c_N PF05470.7 KFH47550.1 - 3.3 5.7 9.5 3.7 5.5 6.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Neur_chan_memb PF02932.11 KFH47550.1 - 4.2 7.1 5.9 4.9 6.9 4.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2890 PF11081.3 KFH47550.1 - 4.9 7.1 21.9 5.3 7.0 15.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) RRN3 PF05327.6 KFH47550.1 - 5.1 5.0 8.4 5.4 5.0 5.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SAPS PF04499.10 KFH47550.1 - 5.7 5.4 9.4 6.3 5.3 6.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TraH_2 PF06871.6 KFH47550.1 - 5.9 6.2 6.1 8.2 5.8 4.2 1.4 1 0 0 1 1 1 0 TraH_2 SDA1 PF05285.7 KFH47550.1 - 9.3 5.4 18.9 10 5.2 13.1 1.1 1 0 0 1 1 1 0 SDA1 DUF740 PF05340.7 KFH47550.1 - 9.6 4.4 13.6 11 4.2 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) F-box PF00646.28 KFH47552.1 - 0.0001 21.8 0.4 0.00025 20.6 0.2 1.7 1 0 0 1 1 1 1 F-box domain WSC PF01822.14 KFH47553.1 - 3.4e-11 42.9 8.4 3.4e-11 42.9 5.9 2.7 2 1 1 3 3 3 1 WSC domain adh_short PF00106.20 KFH47554.1 - 1.5e-32 112.7 0.9 2.1e-32 112.3 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH47554.1 - 2.2e-26 93.1 0.1 2.7e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH47554.1 - 4.4e-13 49.2 0.2 6.7e-13 48.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFH47554.1 - 1.6e-06 27.7 0.1 2.8e-06 26.9 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KFH47554.1 - 0.0077 15.1 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein PA PF02225.17 KFH47554.1 - 0.015 15.0 0.1 0.035 13.8 0.1 1.6 1 0 0 1 1 1 0 PA domain Methyltransf_25 PF13649.1 KFH47554.1 - 0.031 14.6 0.0 0.077 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain WW PF00397.21 KFH47555.1 - 6.8e-06 25.8 2.8 1.5e-05 24.7 2.0 1.6 1 0 0 1 1 1 1 WW domain Ribosomal_L50 PF10501.4 KFH47556.1 - 3e-11 43.2 0.0 6.1e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal subunit 39S SAP PF02037.22 KFH47556.1 - 0.044 13.2 0.0 0.093 12.2 0.0 1.5 1 0 0 1 1 1 0 SAP domain DOPA_dioxygen PF08883.6 KFH47557.1 - 1.9e-31 108.1 0.0 2.9e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family adh_short PF00106.20 KFH47558.1 - 4.8e-11 42.8 0.1 1.2e-10 41.5 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH47558.1 - 2.6e-07 30.6 0.0 3.9e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH47558.1 - 6.8e-06 25.8 0.0 1.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFH47558.1 - 0.00013 21.4 0.1 0.00048 19.6 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.13 KFH47559.1 - 5.9e-38 130.2 0.5 5.9e-38 130.2 0.4 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH47559.1 - 3e-07 30.2 10.6 5.7e-07 29.3 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GHMP_kinases_N PF00288.21 KFH47559.1 - 0.12 12.4 2.8 0.35 10.9 1.9 1.8 1 0 0 1 1 1 0 GHMP kinases N terminal domain LSM PF01423.17 KFH47560.1 - 2.4e-12 46.2 0.0 3.3e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 LSM domain Baculo_44 PF04631.7 KFH47560.1 - 0.035 12.7 0.0 0.041 12.5 0.0 1.0 1 0 0 1 1 1 0 Baculovirus hypothetical protein Trp_DMAT PF11991.3 KFH47560.1 - 0.11 11.6 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Tryptophan dimethylallyltransferase Gly_transf_sug PF04488.10 KFH47561.1 - 2.3e-11 43.9 0.0 4.8e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif RAI1 PF08652.6 KFH47562.1 - 8.7e-30 102.3 0.0 1.5e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease ResIII PF04851.10 KFH47562.1 - 0.0079 16.0 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit MMR_HSR1 PF01926.18 KFH47563.1 - 3.5e-17 62.4 0.2 3.5e-15 55.9 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFH47563.1 - 3.1e-07 29.7 0.3 5.1e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 KFH47563.1 - 0.0006 19.0 0.0 0.0012 18.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KFH47563.1 - 0.0029 17.4 0.1 0.29 10.9 0.0 2.7 2 0 0 2 2 2 1 Dynamin family Miro PF08477.8 KFH47563.1 - 0.029 14.8 0.0 0.072 13.5 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein ArgK PF03308.11 KFH47563.1 - 0.044 12.5 0.0 0.092 11.5 0.0 1.5 1 0 0 1 1 1 0 ArgK protein AIG1 PF04548.11 KFH47563.1 - 0.1 11.7 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 AIG1 family zf-RanBP PF00641.13 KFH47564.1 - 1.2e-18 65.9 12.5 4.4e-11 41.6 0.8 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 KFH47564.1 - 1e-08 34.6 0.0 2.1e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 KFH47564.1 - 5.9e-07 29.9 0.0 9.5e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RRM_6 PF14259.1 KFH47564.1 - 9.9e-06 25.4 0.0 1.8e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DZR PF12773.2 KFH47564.1 - 4.1 7.3 10.8 0.91 9.3 0.8 2.4 2 0 0 2 2 2 0 Double zinc ribbon Rox3 PF08633.5 KFH47565.1 - 2.6e-50 171.4 0.0 3.9e-50 170.8 0.0 1.2 1 0 0 1 1 1 1 Rox3 mediator complex subunit Glyco_hydro_76 PF03663.9 KFH47566.1 - 2.2e-133 445.2 7.2 2.9e-133 444.8 5.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Transglut_core PF01841.14 KFH47567.1 - 2e-11 44.0 0.3 5.1e-11 42.7 0.2 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.12 KFH47567.1 - 9e-08 31.4 0.2 2e-07 30.4 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KFH47567.1 - 8.3e-05 22.0 0.2 0.0002 20.8 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFH47567.1 - 0.00023 20.4 0.1 0.00023 20.4 0.0 2.2 2 0 0 2 2 2 1 SH3 domain FMO-like PF00743.14 KFH47568.1 - 1.8e-34 118.8 0.0 1.5e-19 69.6 0.0 3.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KFH47568.1 - 1.6e-18 67.5 0.0 1.1e-17 64.8 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFH47568.1 - 2.3e-10 39.9 0.0 2.7e-08 33.1 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KFH47568.1 - 4.9e-09 36.3 0.0 1e-07 32.0 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFH47568.1 - 8.3e-09 35.3 1.8 1.9e-07 30.9 0.0 3.3 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KFH47568.1 - 5.8e-07 29.4 0.0 1.9e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KFH47568.1 - 3e-06 26.5 0.0 0.00044 19.4 0.0 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 KFH47568.1 - 3.5e-06 26.1 0.1 0.032 13.1 0.1 3.5 3 1 1 4 4 4 2 FAD dependent oxidoreductase HI0933_like PF03486.9 KFH47568.1 - 0.0016 16.9 0.5 0.054 11.9 0.2 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 KFH47568.1 - 0.017 15.5 1.7 2.6 8.5 0.2 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFH47568.1 - 0.02 13.8 0.1 1.8 7.4 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.15 KFH47568.1 - 0.021 14.9 0.0 0.55 10.3 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 KFH47568.1 - 0.029 14.1 0.1 0.17 11.5 0.1 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DJ-1_PfpI PF01965.19 KFH47568.1 - 0.095 12.1 0.0 4.3 6.7 0.0 2.2 2 0 0 2 2 2 0 DJ-1/PfpI family FAD_binding_3 PF01494.14 KFH47568.1 - 0.097 11.7 0.4 0.51 9.3 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.13 KFH47568.1 - 0.13 12.2 0.0 0.35 10.8 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_2 PF00890.19 KFH47568.1 - 0.19 10.5 1.3 0.47 9.2 0.1 2.2 4 0 0 4 4 4 0 FAD binding domain RRM_1 PF00076.17 KFH47570.1 - 7e-33 112.0 0.0 2.6e-15 55.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH47570.1 - 5.9e-20 71.0 0.0 5.8e-11 42.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH47570.1 - 1.5e-16 59.9 0.0 5.4e-10 38.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 KFH47570.1 - 0.036 13.5 0.9 2.3 7.8 0.1 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain Nup35_RRM_2 PF14605.1 KFH47570.1 - 0.16 11.7 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RmlD_sub_bind PF04321.12 KFH47571.1 - 5.6e-52 176.4 0.0 7.2e-52 176.0 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 KFH47571.1 - 2.3e-24 86.1 0.0 3e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KFH47571.1 - 8.6e-11 41.2 0.0 5.7e-09 35.2 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 KFH47571.1 - 2.9e-09 36.2 0.1 1.5e-05 24.0 0.0 3.0 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KFH47571.1 - 2.8e-08 32.8 0.0 8.6e-08 31.2 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KFH47571.1 - 2.3e-05 24.4 1.0 5.5e-05 23.2 0.7 1.7 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KFH47571.1 - 9.7e-05 22.3 2.5 0.0036 17.2 1.7 2.3 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 KFH47571.1 - 0.0022 17.2 1.0 0.36 10.0 0.2 2.9 2 1 0 2 2 2 1 NmrA-like family KR PF08659.5 KFH47571.1 - 0.066 12.8 2.3 9.6 5.8 1.6 2.5 1 1 0 1 1 1 0 KR domain BEN PF10523.4 KFH47571.1 - 0.082 12.9 0.0 0.3 11.1 0.0 1.9 2 0 0 2 2 2 0 BEN domain APC8 PF04049.8 KFH47572.1 - 4e-49 166.0 0.4 4e-49 166.0 0.2 2.5 3 0 0 3 3 3 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 KFH47572.1 - 1.6e-19 68.6 7.3 7.4e-05 22.1 0.0 7.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFH47572.1 - 2.9e-18 65.2 9.7 6.7e-08 32.0 0.1 7.0 5 1 2 7 7 7 4 TPR repeat TPR_8 PF13181.1 KFH47572.1 - 2.6e-15 54.9 6.3 0.00025 20.5 0.0 6.2 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFH47572.1 - 1.8e-12 46.1 15.1 0.045 13.6 0.0 8.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFH47572.1 - 1.1e-09 38.1 14.3 4.5e-05 23.3 0.2 6.2 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFH47572.1 - 1.8e-09 37.3 8.0 0.024 15.2 0.0 8.4 9 1 1 10 10 9 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFH47572.1 - 2.2e-08 34.5 10.6 3.5e-05 24.3 0.1 6.6 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFH47572.1 - 7.5e-07 28.4 4.8 0.063 13.0 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 KFH47572.1 - 3.4e-06 27.0 8.0 0.51 10.5 0.2 5.7 4 1 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KFH47572.1 - 1.6e-05 24.6 10.6 1.5 8.7 0.2 5.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFH47572.1 - 2.3e-05 24.2 0.1 2.4 8.5 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFH47572.1 - 0.00018 21.7 6.1 22 5.4 0.1 6.7 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFH47572.1 - 0.065 13.7 24.9 3.3 8.3 0.3 8.8 11 1 0 11 11 8 0 Tetratricopeptide repeat DUF2424 PF10340.4 KFH47572.1 - 0.12 10.9 0.0 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) DUF3856 PF12968.2 KFH47572.1 - 1.7 8.4 8.0 0.99 9.2 0.1 3.4 3 1 1 4 4 3 0 Domain of Unknown Function (DUF3856) Abhydrolase_6 PF12697.2 KFH47574.1 - 1.2e-09 38.3 0.0 2e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFH47574.1 - 1.9e-07 30.8 0.0 1.1e-06 28.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFH47574.1 - 3.9e-05 23.4 0.0 0.00029 20.6 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family GATA PF00320.22 KFH47575.1 - 6.8e-05 22.1 3.3 0.0028 16.9 0.3 2.5 2 0 0 2 2 2 2 GATA zinc finger HCO3_cotransp PF00955.16 KFH47576.1 - 7.8e-60 202.9 10.9 5.8e-32 111.0 2.5 2.1 1 1 1 2 2 2 2 HCO3- transporter family Mito_carr PF00153.22 KFH47577.1 - 3.2e-61 203.0 1.2 7e-20 70.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein 3HCDH_N PF02737.13 KFH47580.1 - 2.2e-53 180.5 0.4 2.9e-53 180.2 0.3 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KFH47580.1 - 1.6e-33 114.9 0.0 3.6e-33 113.8 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Saccharop_dh PF03435.13 KFH47580.1 - 0.0036 16.3 0.1 0.0058 15.6 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_2 PF03446.10 KFH47580.1 - 0.0052 16.6 0.1 0.012 15.4 0.0 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 KFH47580.1 - 0.015 15.0 0.4 0.034 13.8 0.3 1.7 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF2680 PF10925.3 KFH47580.1 - 0.015 15.1 0.2 0.39 10.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) F420_oxidored PF03807.12 KFH47580.1 - 0.026 14.9 0.7 0.071 13.5 0.1 2.0 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 KFH47580.1 - 0.068 12.3 0.1 0.12 11.5 0.0 1.5 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.19 KFH47580.1 - 0.071 12.0 0.0 0.099 11.5 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KFH47580.1 - 0.1 12.6 0.4 0.42 10.6 0.3 1.8 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFH47580.1 - 0.11 12.9 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_L4 PF00573.17 KFH47581.1 - 1.6e-37 128.7 0.1 2.2e-37 128.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 KFH47581.1 - 5.3e-27 93.5 1.7 5.3e-27 93.5 1.2 2.0 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain UCH PF00443.24 KFH47582.1 - 2.3e-24 85.9 0.0 3.1e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KFH47582.1 - 2.2e-12 46.8 0.2 4.8e-12 45.8 0.1 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein PGA2 PF07543.7 KFH47583.1 - 1.3e-35 122.2 8.1 1.3e-35 122.2 5.6 1.6 2 0 0 2 2 2 1 Protein trafficking PGA2 Pilt PF15453.1 KFH47583.1 - 1.5 8.3 6.6 2.2 7.8 4.6 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions CDC27 PF09507.5 KFH47583.1 - 3.3 6.8 13.7 4.7 6.3 9.5 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Pol_alpha_B_N PF08418.5 KFH47584.1 - 1.2e-57 195.4 0.0 1.6e-57 194.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 KFH47584.1 - 1e-36 126.1 0.3 2.3e-36 125.0 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B IF4E PF01652.13 KFH47586.1 - 2.7e-51 173.3 0.0 3.9e-51 172.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Methyltransf_26 PF13659.1 KFH47587.1 - 8.9e-13 48.2 0.0 2.4e-12 46.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH47587.1 - 1.7e-09 37.4 0.0 2.9e-09 36.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH47587.1 - 3.5e-08 34.0 0.0 8.1e-08 32.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFH47587.1 - 7.3e-06 25.4 0.0 2.4e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain N6_Mtase PF02384.11 KFH47587.1 - 0.0017 17.5 0.0 0.0024 17.0 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_25 PF13649.1 KFH47587.1 - 0.0018 18.6 0.0 0.0034 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 KFH47587.1 - 0.0057 16.2 0.0 0.056 13.0 0.0 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_10 PF05971.7 KFH47587.1 - 0.0083 15.3 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Ubie_methyltran PF01209.13 KFH47587.1 - 0.061 12.4 0.0 0.093 11.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KFH47587.1 - 0.071 13.5 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 KFH47587.1 - 0.093 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_S14 PF00253.16 KFH47588.1 - 9.9e-18 63.2 4.6 1.3e-17 62.9 3.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.1 KFH47588.1 - 0.008 15.9 0.3 0.01 15.5 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4428) ZZ PF00569.12 KFH47588.1 - 1.5 8.4 4.8 11 5.6 3.3 2.1 1 1 0 1 1 1 0 Zinc finger, ZZ type PTR2 PF00854.16 KFH47589.1 - 2.6e-42 144.9 3.5 6.7e-41 140.2 2.4 2.2 1 1 0 1 1 1 1 POT family MFS_1 PF07690.11 KFH47589.1 - 1.5e-05 23.8 19.2 0.012 14.3 0.3 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily HET PF06985.6 KFH47590.1 - 1.5e-08 34.8 0.0 3.4e-08 33.7 0.0 1.6 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) ELO PF01151.13 KFH47591.1 - 4.7e-63 212.8 16.8 5.5e-63 212.5 11.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family WD40 PF00400.27 KFH47592.1 - 2.2e-56 185.8 21.7 6.3e-08 32.2 0.0 12.1 13 0 0 13 13 13 10 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KFH47592.1 - 0.04 12.6 0.0 0.41 9.3 0.0 2.1 2 0 0 2 2 2 0 Nup133 N terminal like Methyltransf_32 PF13679.1 KFH47593.1 - 9.3e-22 77.2 0.0 1.7e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH47593.1 - 0.051 14.1 0.0 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain HSBP1 PF06825.7 KFH47594.1 - 4.2e-15 55.0 0.5 5.3e-15 54.7 0.4 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.4 KFH47594.1 - 0.051 12.9 0.5 1.2 8.5 0.1 2.1 1 1 1 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF1664 PF07889.7 KFH47594.1 - 0.058 13.1 0.2 0.08 12.7 0.1 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) HR1 PF02185.11 KFH47594.1 - 0.058 13.1 0.4 0.07 12.8 0.3 1.2 1 0 0 1 1 1 0 Hr1 repeat DNA_repr_REX1B PF14966.1 KFH47594.1 - 0.092 13.1 0.1 0.12 12.8 0.1 1.2 1 0 0 1 1 1 0 DNA repair REX1-B IFP_35_N PF07334.8 KFH47594.1 - 0.13 12.2 0.2 0.24 11.4 0.1 1.5 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus CHD5 PF04420.9 KFH47594.1 - 0.14 11.8 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 CHD5-like protein MRP-S31 PF15433.1 KFH47594.1 - 0.16 11.3 1.6 0.16 11.3 1.1 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Macoilin PF09726.4 KFH47595.1 - 3.4 5.8 5.5 4.1 5.5 3.8 1.1 1 0 0 1 1 1 0 Transmembrane protein DEAD PF00270.24 KFH47596.1 - 1.2e-44 151.7 0.0 1.6e-43 148.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFH47596.1 - 1.1e-27 95.7 0.1 2e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFH47596.1 - 0.069 12.9 0.0 0.17 11.7 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.1 KFH47596.1 - 0.14 11.1 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit LSM PF01423.17 KFH47597.1 - 1.8e-21 75.4 0.0 2e-21 75.3 0.0 1.0 1 0 0 1 1 1 1 LSM domain GLE1 PF07817.8 KFH47599.1 - 2.4e-18 66.0 0.0 1.3e-17 63.5 0.0 2.1 1 1 0 1 1 1 1 GLE1-like protein DUF605 PF04652.11 KFH47599.1 - 1.8 7.8 27.9 2.9 7.2 19.4 1.3 1 0 0 1 1 1 0 Vta1 like DKCLD PF08068.7 KFH47600.1 - 3.7e-31 106.8 0.1 6.3e-30 102.8 0.1 2.5 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 KFH47600.1 - 6.6e-25 88.0 0.4 6e-22 78.4 0.3 3.4 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 KFH47600.1 - 6.1e-21 73.9 0.4 1.4e-20 72.7 0.3 1.7 1 0 0 1 1 1 1 PUA domain Med19 PF10278.4 KFH47600.1 - 0.93 9.1 9.4 1.7 8.2 6.2 1.6 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 zf-rbx1 PF12678.2 KFH47601.1 - 5.4e-09 36.0 3.6 1.2e-08 34.9 2.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KFH47601.1 - 1.4e-08 34.4 7.3 4.9e-08 32.6 5.1 1.9 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KFH47601.1 - 1.2e-06 28.0 1.2 2e-06 27.3 0.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFH47601.1 - 1.4e-06 27.9 1.9 3.4e-06 26.6 1.4 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFH47601.1 - 2.1e-05 24.0 4.2 7.2e-05 22.3 2.9 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFH47601.1 - 0.00018 21.4 2.6 0.00018 21.4 1.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFH47601.1 - 0.075 12.7 3.0 0.19 11.4 1.1 2.4 1 1 0 1 1 1 0 RING-type zinc-finger DUF2921 PF11145.3 KFH47601.1 - 0.11 10.1 0.3 0.16 9.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) zf-Apc11 PF12861.2 KFH47601.1 - 0.25 11.2 6.9 0.045 13.6 1.8 2.1 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 KFH47601.1 - 6.2 6.8 5.2 20 5.2 3.6 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain WD40 PF00400.27 KFH47602.1 - 3.6e-28 96.3 5.9 1.1e-06 28.2 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_3 PF13570.1 KFH47602.1 - 0.017 15.3 0.5 0.58 10.4 0.0 3.2 3 0 0 3 3 3 0 PQQ-like domain Kelch_6 PF13964.1 KFH47602.1 - 0.1 12.8 0.1 15 5.9 0.0 2.8 3 0 0 3 3 3 0 Kelch motif BBS2_Mid PF14783.1 KFH47602.1 - 0.1 12.3 0.2 41 4.0 0.0 3.5 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Nha1_C PF08619.5 KFH47602.1 - 4.1 6.5 19.7 0.43 9.7 10.5 1.5 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus WD40 PF00400.27 KFH47603.1 - 1.8e-21 75.1 17.2 6.1e-08 32.2 1.1 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat NLE PF08154.7 KFH47603.1 - 3.6e-18 65.3 0.1 5.7e-18 64.6 0.1 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain PQQ PF01011.16 KFH47603.1 - 0.0098 15.3 0.0 0.51 9.9 0.0 2.9 2 0 0 2 2 2 1 PQQ enzyme repeat RNB PF00773.14 KFH47604.1 - 2.5e-75 253.7 0.0 5.4e-75 252.6 0.0 1.6 1 0 0 1 1 1 1 RNB domain DUF4239 PF14023.1 KFH47604.1 - 0.3 10.4 0.4 0.64 9.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Ric8 PF10165.4 KFH47607.1 - 2.7e-68 230.8 0.0 1.7e-67 228.1 0.0 2.0 1 1 0 1 1 1 1 Guanine nucleotide exchange factor synembryn SPC22 PF04573.7 KFH47608.1 - 4.5e-34 117.1 0.0 4.2e-25 87.9 0.0 2.1 2 0 0 2 2 2 2 Signal peptidase subunit DUF2199 PF09965.4 KFH47608.1 - 0.055 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2199) MKT1_C PF12246.3 KFH47610.1 - 4.8e-56 189.4 0.0 6.5e-56 189.0 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 KFH47610.1 - 9.4e-28 96.3 0.0 2e-27 95.3 0.0 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.12 KFH47610.1 - 0.00013 22.2 0.0 0.0003 20.9 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 KFH47610.1 - 0.013 15.5 0.0 0.03 14.3 0.0 1.6 1 0 0 1 1 1 0 XPG I-region Herpes_gE PF02480.11 KFH47611.1 - 0.067 11.4 0.0 0.11 10.7 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E COX14 PF14880.1 KFH47611.1 - 0.13 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c assembly WD40 PF00400.27 KFH47612.1 - 5e-40 133.9 0.6 4.6e-09 35.8 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KFH47612.1 - 2.8e-27 94.4 0.1 5.8e-27 93.4 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nucleoporin_N PF08801.6 KFH47612.1 - 0.14 10.9 0.0 0.42 9.3 0.0 1.8 1 1 0 1 1 1 0 Nup133 N terminal like Urm1 PF09138.6 KFH47613.1 - 2.4e-32 110.8 0.0 2.7e-32 110.7 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 KFH47613.1 - 0.00018 21.8 0.0 0.00024 21.4 0.0 1.2 1 0 0 1 1 1 1 ThiS family DIOX_N PF14226.1 KFH47614.1 - 1.1e-22 80.7 0.0 1.7e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KFH47614.1 - 4.8e-15 55.6 0.0 8.2e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NmrA PF05368.8 KFH47616.1 - 3.4e-73 245.7 0.0 4.3e-73 245.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFH47616.1 - 0.00031 20.7 0.0 0.019 14.9 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding DUF2498 PF10692.4 KFH47616.1 - 0.042 13.4 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2498) HDA2-3 PF11496.3 KFH47617.1 - 3.4e-07 29.3 0.0 0.00046 19.0 0.0 2.3 2 0 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 HSBP1 PF06825.7 KFH47617.1 - 0.0028 17.1 0.2 0.16 11.5 0.0 2.8 2 0 0 2 2 2 1 Heat shock factor binding protein 1 Mtf2_C PF14061.1 KFH47617.1 - 0.0042 16.9 0.1 0.0085 15.9 0.0 1.5 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 DUF2365 PF10157.4 KFH47617.1 - 0.013 15.4 1.2 0.037 13.9 0.8 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) AAA_13 PF13166.1 KFH47617.1 - 0.61 8.4 17.9 0.95 7.8 12.4 1.2 1 0 0 1 1 1 0 AAA domain Vps54 PF07928.7 KFH47619.1 - 2.5e-45 153.9 0.3 7.3e-45 152.4 0.0 2.0 2 0 0 2 2 2 1 Vps54-like protein DUF2450 PF10475.4 KFH47619.1 - 7.8e-05 21.7 2.6 0.00013 21.0 0.5 2.1 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) Sec8_exocyst PF04048.9 KFH47619.1 - 0.063 12.9 1.4 0.79 9.3 0.2 3.0 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain Fcf1 PF04900.7 KFH47620.1 - 3.4e-38 129.7 0.7 5.6e-38 129.0 0.1 1.6 2 0 0 2 2 2 1 Fcf1 Glyco_hydro_7 PF00840.15 KFH47620.1 - 0.03 12.7 0.0 0.035 12.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 7 Fungal_trans PF04082.13 KFH47621.1 - 9.5e-24 83.6 1.4 1.4e-23 83.0 1.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH47621.1 - 3.1e-07 30.1 13.3 5.9e-07 29.2 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EphA2_TM PF14575.1 KFH47622.1 - 0.0029 17.9 0.0 0.0059 16.9 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain CD34_antigen PF06365.7 KFH47622.1 - 0.24 11.0 0.0 0.38 10.3 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family DZR PF12773.2 KFH47622.1 - 3.2 7.6 7.6 17 5.3 0.7 3.0 2 1 0 2 2 2 0 Double zinc ribbon DUF4048 PF13257.1 KFH47623.1 - 8.5e-06 25.5 27.6 1.2e-05 25.1 12.5 4.4 2 2 1 3 3 3 1 Domain of unknown function (DUF4048) Dicty_REP PF05086.7 KFH47623.1 - 0.18 9.5 1.4 0.26 8.9 1.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ank_2 PF12796.2 KFH47624.1 - 1.8e-39 133.9 0.9 8.3e-15 54.9 0.8 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFH47624.1 - 4.4e-32 108.2 5.0 1.1e-07 31.3 0.1 6.7 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 KFH47624.1 - 5.2e-30 103.2 0.2 6e-09 36.1 0.0 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFH47624.1 - 3e-25 85.7 2.4 0.00016 21.5 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 KFH47624.1 - 1.1e-22 79.5 7.0 4.3e-06 26.8 0.1 6.3 2 2 5 7 7 7 6 Ankyrin repeats (many copies) ECH_C PF13766.1 KFH47625.1 - 4.9e-35 120.2 0.2 1.2e-34 118.9 0.1 1.6 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 KFH47625.1 - 9.9e-26 90.3 0.0 1e-24 87.0 0.0 2.1 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family Fungal_trans_2 PF11951.3 KFH47626.1 - 3.1e-16 58.9 0.0 3.8e-16 58.6 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain GAS2 PF02187.12 KFH47627.1 - 4.6e-05 23.1 0.0 0.00011 21.8 0.0 1.6 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Pmp3 PF01679.12 KFH47628.1 - 5.8e-09 35.5 11.3 2.4e-08 33.5 7.9 2.0 1 1 1 2 2 2 1 Proteolipid membrane potential modulator DUF2244 PF10003.4 KFH47628.1 - 0.13 11.6 0.3 0.15 11.4 0.2 1.1 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Dak1 PF02733.12 KFH47629.1 - 3e-109 364.5 7.3 4.2e-109 364.0 5.1 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 KFH47629.1 - 5.8e-45 153.0 0.3 5.8e-45 153.0 0.2 1.7 2 0 0 2 2 2 1 DAK2 domain Fungal_trans PF04082.13 KFH47630.1 - 8.3e-28 96.9 0.0 1.6e-27 96.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH47630.1 - 1.1e-10 41.2 11.4 1.9e-10 40.4 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain efThoc1 PF11957.3 KFH47630.1 - 0.13 10.7 1.3 0.13 10.7 0.0 1.6 2 0 0 2 2 2 0 THO complex subunit 1 transcription elongation factor DUF217 PF02697.9 KFH47630.1 - 0.43 10.8 2.7 15 5.9 0.0 3.5 3 1 1 4 4 4 0 Uncharacterized ACR, COG1753 Pkinase PF00069.20 KFH47631.1 - 2.2e-69 233.5 0.0 3.3e-69 232.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH47631.1 - 1e-49 168.9 0.0 1.5e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH47631.1 - 1.4e-05 24.2 0.0 7.5e-05 21.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like GPI2 PF06432.6 KFH47632.1 - 2.8 7.2 5.2 3.8 6.7 3.6 1.1 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase LTV PF04180.9 KFH47633.1 - 4.6e-105 352.5 14.8 5.2e-105 352.3 10.3 1.0 1 0 0 1 1 1 1 Low temperature viability protein CAF-1_p150 PF11600.3 KFH47634.1 - 2.2e-05 23.9 18.6 5e-05 22.7 12.9 1.6 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF676 PF05057.9 KFH47634.1 - 0.00013 21.3 0.0 0.00024 20.4 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KFH47634.1 - 0.00024 20.7 0.1 0.00049 19.7 0.0 1.5 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KFH47634.1 - 0.00045 20.1 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH47634.1 - 0.00048 19.9 0.0 0.001 18.8 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 KFH47634.1 - 0.16 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) UPF0227 PF05728.7 KFH47634.1 - 0.18 11.5 0.0 0.18 11.5 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Thioesterase PF00975.15 KFH47634.1 - 0.24 11.5 2.2 1.5 8.9 0.0 2.2 2 0 0 2 2 2 0 Thioesterase domain Hex_IIIa PF02455.11 KFH47634.1 - 0.77 8.3 7.9 1.1 7.8 5.5 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Cohesin_load PF10345.4 KFH47635.1 - 5.7e-89 298.9 6.4 2.8e-72 243.8 2.8 2.1 2 0 0 2 2 2 2 Cohesin loading factor NADH_B2 PF14813.1 KFH47637.1 - 0.019 14.6 0.0 0.046 13.3 0.0 1.6 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 Skp1 PF01466.14 KFH47637.1 - 0.59 10.1 3.4 1 9.4 2.3 1.4 1 0 0 1 1 1 0 Skp1 family, dimerisation domain FLO_LFY PF01698.11 KFH47637.1 - 0.82 8.4 9.6 1.1 8.0 6.7 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Caudo_TAP PF02413.12 KFH47637.1 - 4 7.6 7.6 9.5 6.4 4.7 1.9 1 1 0 1 1 1 0 Caudovirales tail fibre assembly protein Zn_clus PF00172.13 KFH47638.1 - 1.1e-06 28.4 13.8 1.1e-06 28.4 7.3 2.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3014 PF11219.3 KFH47638.1 - 0.025 14.4 0.0 0.04 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3014) TIMELESS PF04821.9 KFH47639.1 - 3.2e-90 301.9 0.1 3.2e-90 301.9 0.1 4.0 5 0 0 5 5 5 1 Timeless protein TIMELESS_C PF05029.8 KFH47639.1 - 5.1e-35 121.4 4.3 5.1e-35 121.4 3.0 3.7 3 2 1 4 4 4 1 Timeless protein C terminal region Cnd1_N PF12922.2 KFH47639.1 - 0.016 14.8 10.4 0.079 12.5 0.2 4.4 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1, N-term Tom7 PF08038.7 KFH47640.1 - 6.1e-18 64.0 0.0 6.7e-18 63.8 0.0 1.0 1 0 0 1 1 1 1 TOM7 family PAT1 PF09770.4 KFH47641.1 - 0.074 11.2 17.2 0.087 11.0 11.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Herpes_UL16 PF03044.9 KFH47641.1 - 0.24 10.3 4.1 0.082 11.8 0.7 1.9 1 1 0 1 1 1 0 Herpesvirus UL16/UL94 family Malic_M PF03949.10 KFH47642.1 - 5.1e-90 301.4 0.0 6.8e-90 301.0 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KFH47642.1 - 1.8e-72 242.7 0.0 2.8e-72 242.1 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Zn_clus PF00172.13 KFH47643.1 - 7.9e-08 32.0 5.7 1.5e-07 31.2 4.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFH47643.1 - 0.02 13.5 0.2 0.15 10.6 0.1 2.0 2 0 0 2 2 2 0 Fungal specific transcription factor domain Copper-fist PF00649.13 KFH47643.1 - 0.25 10.5 2.9 0.6 9.3 2.0 1.6 1 0 0 1 1 1 0 Copper fist DNA binding domain Pkinase PF00069.20 KFH47644.1 - 8.1e-70 234.9 0.0 1.2e-69 234.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH47644.1 - 2e-36 125.4 0.0 4e-36 124.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH47644.1 - 0.00037 19.5 0.0 0.00059 18.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFH47644.1 - 0.0061 15.6 0.1 0.012 14.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Homeobox PF00046.24 KFH47645.1 - 1.9e-17 62.6 1.9 3.3e-17 61.8 1.3 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFH47645.1 - 0.0018 17.9 0.1 0.0045 16.6 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain Aconitase PF00330.15 KFH47646.1 - 1.3e-69 234.8 0.1 2.2e-44 151.7 0.0 2.2 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KFH47646.1 - 1.9e-23 82.9 0.0 4.4e-23 81.8 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain polyprenyl_synt PF00348.12 KFH47647.1 - 5.4e-69 231.9 0.0 6.4e-69 231.6 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase WD40 PF00400.27 KFH47648.1 - 6.9e-65 212.7 27.1 2.6e-09 36.6 0.0 12.1 11 2 0 11 11 11 10 WD domain, G-beta repeat Utp13 PF08625.6 KFH47648.1 - 1.6e-44 150.9 0.1 2.8e-44 150.2 0.0 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 KFH47648.1 - 9.1e-05 20.7 9.3 0.085 10.9 2.4 4.8 3 2 1 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFH47648.1 - 0.00011 21.0 3.8 0.2 10.3 0.2 4.7 3 1 1 4 4 4 1 Nup133 N terminal like BBS2_Mid PF14783.1 KFH47648.1 - 0.099 12.4 0.0 16 5.2 0.0 4.4 6 1 0 6 6 6 0 Ciliary BBSome complex subunit 2, middle region Fn_bind PF02986.9 KFH47648.1 - 0.34 10.4 2.6 2.1 7.9 1.8 2.2 2 0 0 2 2 2 0 Fibronectin binding repeat ZZ PF00569.12 KFH47649.1 - 0.0057 16.1 3.0 2.5 7.7 0.1 3.2 3 0 0 3 3 3 2 Zinc finger, ZZ type MIP PF00230.15 KFH47650.1 - 3.3e-41 141.2 6.2 4.4e-41 140.8 4.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein Peptidase_M41 PF01434.13 KFH47652.1 - 8.3e-78 260.7 0.2 1.2e-77 260.1 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KFH47652.1 - 1.6e-41 141.5 0.0 6.8e-41 139.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 KFH47652.1 - 7.8e-11 42.1 0.0 2.1e-10 40.7 0.0 1.8 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.9 KFH47652.1 - 0.0007 19.3 0.2 0.0049 16.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KFH47652.1 - 0.0029 16.3 0.1 0.0051 15.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 KFH47652.1 - 0.0033 18.2 0.6 0.023 15.5 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KFH47652.1 - 0.0069 16.5 0.7 0.7 10.0 0.0 3.2 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.1 KFH47652.1 - 0.0071 16.0 1.6 0.053 13.2 0.8 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_2 PF07724.9 KFH47652.1 - 0.0082 16.0 0.0 0.051 13.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KFH47652.1 - 0.015 15.3 0.2 0.51 10.2 0.1 3.1 1 1 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.1 KFH47652.1 - 0.018 14.4 1.8 0.034 13.5 0.3 2.2 2 1 1 3 3 3 0 AAA domain Zeta_toxin PF06414.7 KFH47652.1 - 0.021 13.8 0.0 0.056 12.5 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin RuvB_N PF05496.7 KFH47652.1 - 0.022 13.7 0.0 0.051 12.6 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 KFH47652.1 - 0.039 13.3 0.0 0.11 11.8 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 KFH47652.1 - 0.044 13.6 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 KFH47653.1 - 1.2e-59 200.9 0.2 1.6e-59 200.5 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KFH47653.1 - 6.9e-25 87.1 0.0 1.6e-24 85.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KFH47653.1 - 1.7e-16 60.0 3.6 4.3e-16 58.7 2.5 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KFH47653.1 - 1.4e-05 24.9 0.0 2.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFH47653.1 - 0.00052 20.4 0.0 0.00094 19.6 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 KFH47653.1 - 0.065 12.7 0.2 9.6 5.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 KFH47653.1 - 0.11 11.6 0.1 0.33 10.0 0.0 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Glycogen_syn PF05693.8 KFH47654.1 - 0 1143.7 0.0 0 1143.5 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 KFH47654.1 - 1e-05 25.0 0.0 0.0094 15.3 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 KFH47654.1 - 1.8e-05 24.3 0.1 3.5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 KFH47654.1 - 7.3e-05 22.9 0.0 0.0002 21.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Prp19_bind PF06991.6 KFH47655.1 - 5.9e-42 143.8 32.7 5.9e-42 143.8 22.7 2.5 2 1 1 3 3 3 1 Splicing factor, Prp19-binding domain Y2_Tnp PF04986.8 KFH47655.1 - 7.6 6.2 7.5 2.1 8.0 2.5 1.9 1 1 1 2 2 2 0 Putative transposase UPF0220 PF05255.6 KFH47656.1 - 7.3e-66 220.4 3.8 8.2e-66 220.3 2.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF3816 PF12822.2 KFH47656.1 - 0.26 11.1 4.8 0.24 11.2 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3816) DUF410 PF04190.8 KFH47657.1 - 1.2e-48 165.9 0.0 1.4e-48 165.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Thioredoxin PF00085.15 KFH47658.1 - 1.6e-61 204.4 0.0 3.8e-30 103.6 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 KFH47658.1 - 1.6e-23 83.1 0.4 6e-23 81.2 0.2 2.0 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 KFH47658.1 - 6.3e-22 77.8 0.2 2.5e-09 37.3 0.0 3.1 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KFH47658.1 - 4.5e-14 52.2 0.0 5.2e-06 26.4 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 KFH47658.1 - 1.6e-13 50.6 0.7 1.2e-05 25.3 0.0 3.2 3 2 0 3 3 2 2 Thioredoxin-like AhpC-TSA PF00578.16 KFH47658.1 - 1.9e-08 34.0 0.1 0.0041 16.7 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 KFH47658.1 - 7e-07 28.8 0.2 0.032 13.7 0.1 2.4 2 0 0 2 2 2 2 Redoxin Thioredoxin_6 PF13848.1 KFH47658.1 - 1.3e-05 25.0 0.2 0.14 11.9 0.1 2.9 1 1 2 3 3 3 3 Thioredoxin-like domain Thioredoxin_4 PF13462.1 KFH47658.1 - 3.2e-05 24.0 1.3 0.088 12.8 0.2 3.1 2 2 1 3 3 3 2 Thioredoxin ERp29_N PF07912.8 KFH47658.1 - 0.00029 20.7 0.6 0.028 14.3 0.0 3.1 3 0 0 3 3 3 1 ERp29, N-terminal domain Thioredoxin_3 PF13192.1 KFH47658.1 - 0.00036 20.2 0.0 0.61 9.9 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_9 PF14595.1 KFH47658.1 - 0.00067 19.2 0.0 0.43 10.1 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Glutaredoxin PF00462.19 KFH47658.1 - 0.002 18.0 0.3 2 8.4 0.0 3.2 2 1 0 2 2 2 1 Glutaredoxin HyaE PF07449.6 KFH47658.1 - 0.021 14.7 0.0 0.2 11.5 0.0 2.4 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Mu-like_Com PF10122.4 KFH47658.1 - 0.22 10.6 0.4 7.4 5.7 0.0 2.3 2 0 0 2 2 2 0 Mu-like prophage protein Com Flagellin_IN PF07196.8 KFH47658.1 - 1.3 9.0 4.7 8.2 6.5 0.0 3.2 3 0 0 3 3 3 0 Flagellin hook IN motif AMP-binding PF00501.23 KFH47659.1 - 6.9e-12 44.4 0.1 6.6e-06 24.7 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme F-box-like PF12937.2 KFH47660.1 - 1.5e-05 24.6 0.2 3e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like Syntaxin-6_N PF09177.6 KFH47662.1 - 6.1e-26 90.6 2.2 1.2e-25 89.6 0.1 2.2 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 KFH47662.1 - 2.6e-13 49.4 6.0 2.6e-13 49.4 4.2 2.2 2 0 0 2 2 2 1 SNARE domain Fez1 PF06818.10 KFH47662.1 - 0.0068 16.4 5.1 0.0093 16.0 3.5 1.2 1 0 0 1 1 1 1 Fez1 Prominin PF05478.6 KFH47662.1 - 0.0068 14.0 0.2 0.0089 13.6 0.1 1.2 1 0 0 1 1 1 1 Prominin Filament PF00038.16 KFH47662.1 - 0.06 12.8 7.1 0.55 9.6 1.0 2.7 2 1 1 3 3 3 0 Intermediate filament protein AATF-Che1 PF13339.1 KFH47662.1 - 0.11 12.6 3.8 0.14 12.3 0.6 2.1 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor LIF_OSM PF01291.12 KFH47662.1 - 0.17 11.7 2.1 0.44 10.4 0.2 2.2 2 1 0 2 2 2 0 LIF / OSM family PilJ PF13675.1 KFH47662.1 - 0.18 12.1 8.9 0.24 11.7 1.1 2.3 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF972 PF06156.8 KFH47662.1 - 0.24 11.7 1.8 1.6 9.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) TPR_MLP1_2 PF07926.7 KFH47662.1 - 0.27 10.9 8.1 3.8 7.2 1.1 2.7 2 2 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3606 PF12244.3 KFH47662.1 - 0.29 10.7 2.5 0.49 10.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) CCDC155 PF14662.1 KFH47662.1 - 0.44 10.1 6.5 0.74 9.3 0.2 2.2 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 DUF3166 PF11365.3 KFH47662.1 - 0.46 10.9 4.3 2 8.9 0.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) Prefoldin_2 PF01920.15 KFH47662.1 - 0.78 9.5 5.7 11 5.8 0.6 2.9 2 1 0 2 2 2 0 Prefoldin subunit Spc24 PF08286.6 KFH47662.1 - 1.1 8.9 4.3 0.91 9.2 0.1 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 RmuC PF02646.11 KFH47662.1 - 1.3 7.8 5.3 8.1 5.1 0.2 2.1 2 0 0 2 2 2 0 RmuC family APG6 PF04111.7 KFH47662.1 - 2.3 7.1 4.6 8.9 5.2 0.2 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF4164 PF13747.1 KFH47662.1 - 3 8.0 9.6 13 5.9 2.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) NPV_P10 PF05531.7 KFH47662.1 - 5.3 7.3 7.6 12 6.2 0.3 3.0 3 1 0 3 3 2 0 Nucleopolyhedrovirus P10 protein Sulfotransfer_3 PF13469.1 KFH47663.1 - 0.00029 21.8 0.1 0.00061 20.7 0.1 1.4 1 1 0 1 1 1 1 Sulfotransferase family Proteasome PF00227.21 KFH47664.1 - 9.3e-31 106.5 0.0 1e-30 106.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit RNA_pol_L_2 PF13656.1 KFH47665.1 - 2.7e-23 81.2 0.1 3.4e-23 80.8 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KFH47665.1 - 8.4e-09 34.4 0.0 1.2e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain 5_nucleotid_C PF02872.13 KFH47665.1 - 0.072 13.0 0.0 0.094 12.6 0.0 1.2 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain NPCC PF08058.6 KFH47667.1 - 1.7e-29 102.5 0.1 5.2e-28 97.7 0.1 2.1 1 1 0 1 1 1 1 Nuclear pore complex component Glyco_hydro_43 PF04616.9 KFH47668.1 - 5e-23 81.6 0.0 1.3e-21 76.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Calici_MSP PF05752.6 KFH47668.1 - 0.015 14.9 0.2 0.024 14.2 0.1 1.2 1 0 0 1 1 1 0 Calicivirus minor structural protein ERG2_Sigma1R PF04622.7 KFH47669.1 - 5.5e-96 319.9 0.1 6.2e-96 319.8 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Cupin_3 PF05899.7 KFH47669.1 - 0.14 11.5 0.1 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Peptidase_C48 PF02902.14 KFH47670.1 - 1.8e-33 115.9 0.0 3.3e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DNA_pol_A_exo1 PF01612.15 KFH47671.1 - 2.9e-18 65.9 0.0 4e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease DUF2934 PF11154.3 KFH47671.1 - 0.97 8.8 6.2 3.2 7.1 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2934) Ferritin_2 PF13668.1 KFH47672.1 - 1.5e-38 131.8 1.1 2.3e-38 131.2 0.8 1.3 1 0 0 1 1 1 1 Ferritin-like domain Thymidylat_synt PF00303.14 KFH47673.1 - 2.9e-117 390.4 0.0 3.3e-117 390.2 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase XRN_N PF03159.13 KFH47674.1 - 3.1e-102 340.9 0.0 5.6e-102 340.1 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus DUF2533 PF10752.4 KFH47674.1 - 0.26 11.6 1.0 0.68 10.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2533) zf-H2C2_2 PF13465.1 KFH47676.1 - 2e-16 59.3 33.2 6.8e-09 35.5 1.6 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 KFH47676.1 - 8.1e-16 57.3 25.4 0.00034 20.7 0.7 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFH47676.1 - 6.8e-11 41.7 20.0 0.0071 16.6 0.2 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 KFH47676.1 - 0.18 12.0 12.2 7.4 6.9 0.7 4.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type C1_4 PF07975.7 KFH47676.1 - 4.5 7.3 7.7 2.6 8.1 2.9 2.5 1 1 0 1 1 1 0 TFIIH C1-like domain Ribosomal_S28e PF01200.13 KFH47677.1 - 4.1e-34 116.1 1.9 4.5e-34 116.0 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e CN_hydrolase PF00795.17 KFH47678.1 - 4.9e-14 52.1 0.0 8.5e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MCM PF00493.18 KFH47680.1 - 4.8e-141 469.3 0.1 6.6e-141 468.8 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KFH47680.1 - 2.5e-19 69.9 1.2 5e-19 68.9 0.4 1.8 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KFH47680.1 - 1.9e-06 27.2 0.0 0.00019 20.6 0.0 2.3 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KFH47680.1 - 7.8e-06 25.6 0.0 2.3e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KFH47680.1 - 0.0004 19.9 0.0 0.0028 17.2 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 KFH47680.1 - 0.022 14.9 0.2 0.13 12.5 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KFH47680.1 - 0.032 13.6 0.1 0.44 10.0 0.1 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase_2 PF13335.1 KFH47680.1 - 0.056 13.8 1.3 0.14 12.5 0.3 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DER1 PF04511.10 KFH47681.1 - 1.8e-21 76.5 2.8 2.1e-21 76.3 2.0 1.0 1 0 0 1 1 1 1 Der1-like family Gly-zipper_OmpA PF13436.1 KFH47681.1 - 6.1 6.5 6.8 0.47 10.1 0.9 1.8 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain SAC3_GANP PF03399.11 KFH47682.1 - 2.1e-40 138.4 0.0 3.3e-40 137.8 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Cul7 PF11515.3 KFH47682.1 - 0.32 10.9 0.9 0.58 10.1 0.1 1.7 2 0 0 2 2 2 0 Mouse development and cellular proliferation protein Cullin-7 COX5A PF02284.11 KFH47683.1 - 2.2e-40 136.9 0.3 2.9e-40 136.5 0.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DHC_N1 PF08385.7 KFH47683.1 - 0.12 10.7 0.2 3.7 5.7 0.0 2.0 1 1 1 2 2 2 0 Dynein heavy chain, N-terminal region 1 DUF4188 PF13826.1 KFH47684.1 - 4.5e-30 104.1 0.0 6.2e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.1 KFH47684.1 - 0.015 14.3 0.2 0.035 13.1 0.1 1.7 1 1 0 1 1 1 0 Haem-containing dehydratase Rep_fac_C PF08542.6 KFH47686.1 - 4.1e-20 71.5 0.0 8.8e-20 70.4 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KFH47686.1 - 2.3e-11 43.6 0.0 1.6e-09 37.5 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 KFH47686.1 - 2.7e-11 43.7 0.0 4.7e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KFH47686.1 - 1.8e-07 31.0 0.0 3.6e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFH47686.1 - 2.1e-06 27.8 0.0 7.2e-05 22.8 0.0 2.4 2 1 1 3 3 2 1 AAA ATPase domain RuvB_N PF05496.7 KFH47686.1 - 7e-06 25.2 0.0 1.8e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KFH47686.1 - 8.8e-06 25.8 0.2 0.0069 16.5 0.1 2.7 2 1 0 2 2 1 1 AAA domain AAA_3 PF07726.6 KFH47686.1 - 0.00015 21.3 0.0 0.00029 20.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 KFH47686.1 - 0.00017 21.2 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 KFH47686.1 - 0.00033 20.2 0.0 0.046 13.1 0.0 2.2 1 1 1 2 2 2 1 AAA-like domain AAA_19 PF13245.1 KFH47686.1 - 0.0022 17.6 0.0 0.0048 16.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Rad17 PF03215.10 KFH47686.1 - 0.0027 16.4 0.0 2.3 6.8 0.0 2.6 2 1 1 3 3 3 2 Rad17 cell cycle checkpoint protein Mg_chelatase PF01078.16 KFH47686.1 - 0.0037 16.4 0.0 0.031 13.4 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 KFH47686.1 - 0.0058 16.3 0.4 0.033 13.9 0.1 2.2 2 1 1 3 3 2 1 NTPase ArgK PF03308.11 KFH47686.1 - 0.0075 15.0 0.0 0.016 14.0 0.0 1.5 1 0 0 1 1 1 1 ArgK protein DEAD PF00270.24 KFH47686.1 - 0.0081 15.6 0.1 0.35 10.3 0.0 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_25 PF13481.1 KFH47686.1 - 0.0086 15.4 0.1 0.11 11.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KFH47686.1 - 0.0087 15.5 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family DNA_pol3_delta PF06144.8 KFH47686.1 - 0.0096 15.4 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_11 PF13086.1 KFH47686.1 - 0.012 15.1 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KFH47686.1 - 0.019 15.2 0.0 0.037 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.1 KFH47686.1 - 0.025 14.5 0.0 0.074 12.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 KFH47686.1 - 0.036 13.2 0.0 0.063 12.4 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DNA_pol3_gamma3 PF12169.3 KFH47686.1 - 0.038 13.7 0.1 0.5 10.1 0.0 2.5 3 0 0 3 3 3 0 DNA polymerase III subunits gamma and tau domain III AAA_5 PF07728.9 KFH47686.1 - 0.091 12.4 0.2 0.4 10.3 0.0 2.1 3 1 0 3 3 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 KFH47686.1 - 0.12 11.1 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DNA_ligase_A_M PF01068.16 KFH47687.1 - 8.1e-20 71.0 0.0 1.6e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KFH47687.1 - 3.6e-08 33.4 0.0 7.8e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus Aminotran_1_2 PF00155.16 KFH47688.1 - 3.1e-06 26.4 0.0 1.4e-05 24.2 0.0 2.0 2 1 0 2 2 2 1 Aminotransferase class I and II Proteasome PF00227.21 KFH47689.1 - 4.9e-55 185.7 0.0 6.5e-55 185.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KFH47689.1 - 1.1e-13 50.1 0.0 2.2e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3137 PF11335.3 KFH47689.1 - 0.01 15.5 0.1 0.24 11.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3137) COPI_assoc PF08507.5 KFH47690.1 - 3e-36 124.1 9.3 3.2e-36 124.0 6.5 1.0 1 0 0 1 1 1 1 COPI associated protein Ycf66_N PF07444.6 KFH47690.1 - 0.032 13.9 1.8 0.037 13.7 0.4 1.8 1 1 0 1 1 1 0 Ycf66 protein N-terminus DUF3096 PF11295.3 KFH47690.1 - 0.087 12.3 0.7 0.087 12.3 0.5 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3096) Cg6151-P PF10233.4 KFH47690.1 - 0.76 9.7 7.5 1.7 8.6 4.9 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein CG6151-P Neurensin PF14927.1 KFH47690.1 - 2.2 7.6 4.5 6 6.2 3.1 2.0 1 1 0 1 1 1 0 Neurensin Reticulon PF02453.12 KFH47691.1 - 4e-39 133.9 3.9 5.8e-39 133.3 2.7 1.2 1 0 0 1 1 1 1 Reticulon Prominin PF05478.6 KFH47691.1 - 0.0085 13.6 0.0 0.013 13.0 0.0 1.3 1 0 0 1 1 1 1 Prominin Abhydrolase_9_N PF15420.1 KFH47691.1 - 0.24 11.1 6.1 0.089 12.5 0.7 2.1 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Methyltransf_8 PF05148.10 KFH47692.1 - 1.3e-58 198.1 0.0 2e-57 194.3 0.0 2.6 3 1 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 KFH47692.1 - 1.5e-05 25.3 0.2 6.3e-05 23.3 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH47692.1 - 0.017 14.7 0.0 4.3 6.9 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.1 KFH47692.1 - 0.031 13.9 0.3 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Mitofilin PF09731.4 KFH47692.1 - 0.25 9.9 20.5 0.34 9.5 14.2 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SOBP PF15279.1 KFH47692.1 - 1.1 9.5 16.8 1.7 8.9 11.7 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein SAPS PF04499.10 KFH47692.1 - 5.5 5.5 7.9 7.6 5.0 5.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mito_fiss_reg PF05308.6 KFH47692.1 - 8.1 5.7 20.9 0.24 10.7 7.2 2.2 1 1 1 2 2 2 0 Mitochondrial fission regulator CPSF100_C PF13299.1 KFH47692.1 - 8.2 6.5 17.5 3.6e+02 1.2 12.0 2.4 1 1 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal zf-CCHC_2 PF13696.1 KFH47693.1 - 2e-05 24.0 2.7 2e-05 24.0 1.9 2.8 2 1 0 2 2 2 1 Zinc knuckle DUF500 PF04366.7 KFH47694.1 - 9.5e-22 76.7 0.0 1.7e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) Hexokinase_2 PF03727.11 KFH47695.1 - 1.3e-20 73.6 0.0 2e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KFH47695.1 - 1.5e-16 60.3 0.0 5.8e-16 58.4 0.0 2.0 1 1 0 1 1 1 1 Hexokinase Myb_DNA-binding PF00249.26 KFH47696.1 - 0.041 13.9 1.9 0.048 13.7 0.0 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain Adeno_VII PF03228.9 KFH47696.1 - 0.6 10.7 3.7 0.94 10.0 0.1 2.5 2 0 0 2 2 2 0 Adenoviral core protein VII NOGCT PF08155.6 KFH47697.1 - 6.8e-28 96.1 1.0 6.8e-28 96.1 0.7 1.9 2 0 0 2 2 2 1 NOGCT (NUC087) domain NOG1 PF06858.9 KFH47697.1 - 1.1e-26 92.4 0.5 1.1e-26 92.4 0.3 1.9 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 KFH47697.1 - 1.6e-15 57.0 0.0 3.3e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFH47697.1 - 8.7e-09 34.8 0.0 2.5e-08 33.3 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 KFH47697.1 - 9e-05 22.9 0.4 0.00068 20.1 0.0 2.6 3 0 0 3 3 3 1 Miro-like protein Dynamin_N PF00350.18 KFH47697.1 - 0.0029 17.4 0.0 2.3 7.9 0.0 2.8 1 1 1 2 2 2 2 Dynamin family Ras PF00071.17 KFH47697.1 - 0.0032 16.8 0.0 0.0079 15.5 0.0 1.7 1 0 0 1 1 1 1 Ras family Amidohydro_4 PF13147.1 KFH47698.1 - 1.2e-08 35.3 0.1 1.9e-07 31.3 0.0 2.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KFH47698.1 - 0.00015 21.5 0.2 0.00071 19.3 0.1 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KFH47698.1 - 0.066 13.0 0.0 0.19 11.5 0.0 1.8 1 0 0 1 1 1 0 Amidohydrolase Soyouz_module PF14313.1 KFH47698.1 - 0.082 12.4 1.0 12 5.5 0.0 3.4 2 1 1 3 3 3 0 N-terminal region of Paramyxovirinae phosphoprotein (P) PDZ_1 PF12812.2 KFH47699.1 - 1.2e-54 182.1 0.0 3.2e-33 113.4 0.0 2.5 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.1 KFH47699.1 - 2e-12 47.1 0.2 1.1e-11 44.7 0.0 2.3 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 KFH47699.1 - 3.6e-12 46.0 0.1 0.0046 16.8 0.0 4.5 4 0 0 4 4 4 4 PDZ domain PDZ PF00595.19 KFH47699.1 - 6e-07 29.5 0.0 0.02 15.0 0.0 4.0 4 0 0 4 4 4 2 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 KFH47699.1 - 0.057 13.2 0.4 5.5 6.8 0.1 3.7 4 0 0 4 4 4 0 Tricorn protease PDZ domain Peptidase_S7 PF00949.16 KFH47699.1 - 0.19 11.1 0.5 0.41 10.0 0.4 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease MFS_1 PF07690.11 KFH47700.1 - 3e-24 85.3 29.8 6.1e-14 51.5 17.6 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Spc97_Spc98 PF04130.8 KFH47701.1 - 6.9e-73 245.7 0.0 8.9e-73 245.4 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF3028 PF11229.3 KFH47701.1 - 0.007 14.7 0.0 0.01 14.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3028) Aldo_ket_red PF00248.16 KFH47702.1 - 1.1e-50 172.0 0.0 3.8e-50 170.3 0.0 1.7 2 0 0 2 2 2 1 Aldo/keto reductase family MRP-L47 PF06984.8 KFH47703.1 - 2.3e-21 75.4 0.2 4.3e-21 74.6 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Clc-like PF07062.7 KFH47703.1 - 0.097 11.9 0.7 0.16 11.1 0.5 1.3 1 0 0 1 1 1 0 Clc-like NPR2 PF06218.6 KFH47704.1 - 2.3e-118 395.6 0.0 1.8e-100 336.6 0.0 2.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 DDHD PF02862.12 KFH47705.1 - 0.053 13.3 2.6 0.067 12.9 1.8 1.1 1 0 0 1 1 1 0 DDHD domain DTHCT PF08070.6 KFH47705.1 - 0.055 14.1 13.9 0.17 12.5 2.5 2.3 1 1 1 2 2 2 0 DTHCT (NUC029) region ORC6 PF05460.8 KFH47705.1 - 0.12 11.3 5.9 0.15 11.1 4.1 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) IER PF05760.7 KFH47705.1 - 0.53 10.1 4.7 0.62 9.9 3.2 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) Sds3 PF08598.6 KFH47705.1 - 0.57 9.6 4.1 0.75 9.2 2.8 1.1 1 0 0 1 1 1 0 Sds3-like eIF-3c_N PF05470.7 KFH47705.1 - 1.8 6.5 6.5 2.3 6.2 4.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SGL PF08450.7 KFH47706.1 - 1.7e-27 96.4 0.0 2.4e-27 95.9 0.0 1.3 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 KFH47706.1 - 3e-05 23.9 0.0 0.00014 21.7 0.0 2.1 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.15 KFH47706.1 - 9.4e-05 22.3 0.0 0.00067 19.5 0.0 2.3 2 0 0 2 2 2 1 Arylesterase FA_hydroxylase PF04116.8 KFH47707.1 - 2.6e-16 60.0 16.4 2.6e-16 60.0 11.4 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Virul_fac_BrkB PF03631.10 KFH47708.1 - 0.018 14.3 0.4 0.032 13.5 0.3 1.3 1 0 0 1 1 1 0 Virulence factor BrkB Nsp1 PF11501.3 KFH47708.1 - 0.059 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Non structural protein Nsp1 MFS_1 PF07690.11 KFH47709.1 - 4.2e-40 137.5 10.3 4.2e-40 137.5 7.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH47709.1 - 4.8e-09 35.3 6.9 4.8e-09 35.3 4.8 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 KFH47709.1 - 1.8e-05 23.3 18.4 0.00031 19.2 2.2 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein Nuc_H_symport PF03825.11 KFH47709.1 - 0.0076 15.0 1.2 0.0076 15.0 0.8 1.8 2 0 0 2 2 2 1 Nucleoside H+ symporter MFS_3 PF05977.8 KFH47709.1 - 1.5 6.8 8.0 1 7.4 1.1 2.3 2 0 0 2 2 2 0 Transmembrane secretion effector MFS_1 PF07690.11 KFH47711.1 - 7.5e-34 116.9 24.1 5.7e-27 94.3 4.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH47711.1 - 4.4e-10 38.7 16.6 5e-09 35.2 5.3 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 KFH47711.1 - 0.0044 15.4 4.1 0.0044 15.4 2.9 2.8 2 1 0 2 2 2 1 MFS/sugar transport protein Glyco_hydro_68 PF02435.11 KFH47711.1 - 0.24 10.0 0.0 0.35 9.5 0.0 1.1 1 0 0 1 1 1 0 Levansucrase/Invertase CUE PF02845.11 KFH47712.1 - 2.5e-10 39.6 0.0 3.7e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 CUE domain SNF2_N PF00176.18 KFH47714.1 - 4.4e-70 235.8 0.0 7.8e-70 235.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 KFH47714.1 - 3.3e-17 62.3 0.0 6.9e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 KFH47714.1 - 6.1e-12 45.2 0.0 1.6e-11 43.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 KFH47714.1 - 1.9e-07 30.8 8.0 5.6e-07 29.2 5.5 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFH47714.1 - 7.9e-07 28.9 9.9 7.9e-07 28.9 6.9 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFH47714.1 - 8.1e-07 28.5 10.0 8.1e-07 28.5 6.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFH47714.1 - 2.9e-06 26.8 8.1 2.5e-05 23.8 4.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFH47714.1 - 0.00033 20.3 7.1 0.0008 19.0 4.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFH47714.1 - 0.0033 17.2 8.1 0.0069 16.2 5.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 KFH47714.1 - 0.0048 16.6 1.9 0.012 15.3 1.3 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KFH47714.1 - 0.012 15.3 8.5 0.012 15.3 5.9 2.0 2 0 0 2 2 2 0 RING-type zinc-finger zf-Apc11 PF12861.2 KFH47714.1 - 0.074 12.9 1.8 0.17 11.7 1.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 KFH47714.1 - 0.2 11.2 6.0 0.5 9.9 3.9 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 KFH47714.1 - 0.27 11.3 7.7 1.2 9.3 5.3 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger Fungal_trans PF04082.13 KFH47715.1 - 1.3e-08 34.0 0.3 2.5e-08 33.1 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH47715.1 - 4e-06 26.6 10.0 4e-06 26.6 6.9 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DASH_Spc34 PF08657.5 KFH47716.1 - 0.23 11.1 7.0 1.4 8.4 4.1 2.1 2 0 0 2 2 2 0 DASH complex subunit Spc34 DUF3482 PF11981.3 KFH47716.1 - 0.39 9.8 5.1 0.63 9.2 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3482) OmpH PF03938.9 KFH47716.1 - 4.6 7.1 8.2 0.29 11.0 2.2 1.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) UQ_con PF00179.21 KFH47717.1 - 2.5e-09 36.6 0.0 4e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme BRE PF06113.7 KFH47717.1 - 0.084 11.8 0.1 0.12 11.3 0.1 1.1 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) RWD PF05773.17 KFH47717.1 - 0.11 12.3 0.1 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 RWD domain tRNA-synt_1b PF00579.20 KFH47718.1 - 7.3e-72 241.9 0.0 1.1e-71 241.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) HMG_box PF00505.14 KFH47719.1 - 5.8e-06 26.4 0.0 1.5e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFH47719.1 - 0.0019 18.5 0.4 0.0049 17.2 0.0 1.9 2 0 0 2 2 2 1 HMG-box domain SLAC1 PF03595.12 KFH47720.1 - 5.9e-95 317.6 47.7 6.7e-95 317.5 33.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Sec62 PF03839.11 KFH47721.1 - 1.5e-50 171.7 1.7 1.5e-50 171.7 1.2 1.6 2 0 0 2 2 2 1 Translocation protein Sec62 cobW PF02492.14 KFH47722.1 - 6.2e-45 152.8 0.3 8.3e-45 152.4 0.2 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 KFH47722.1 - 0.0022 16.8 1.9 1.2 7.8 0.1 2.8 3 0 0 3 3 3 2 ArgK protein AAA_22 PF13401.1 KFH47722.1 - 0.0027 17.8 0.4 0.21 11.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain ATP_bind_1 PF03029.12 KFH47722.1 - 0.0037 16.8 0.2 0.26 10.7 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 KFH47722.1 - 0.0038 16.6 0.1 1 8.7 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_23 PF13476.1 KFH47722.1 - 0.011 16.0 0.2 0.037 14.3 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KFH47722.1 - 0.011 15.9 0.3 0.035 14.4 0.1 1.9 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KFH47722.1 - 0.013 16.0 0.1 0.45 11.0 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_19 PF13245.1 KFH47722.1 - 0.013 15.2 0.1 0.032 13.9 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain MMR_HSR1 PF01926.18 KFH47722.1 - 0.025 14.5 0.7 0.086 12.8 0.5 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 KFH47722.1 - 0.031 13.7 0.0 0.08 12.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.1 KFH47722.1 - 0.039 13.5 0.7 1.3 8.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KFH47722.1 - 0.039 13.6 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_10 PF12846.2 KFH47722.1 - 0.055 12.8 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Septin PF00735.13 KFH47722.1 - 0.056 12.4 2.5 1.9 7.4 0.2 2.4 2 1 0 2 2 2 0 Septin DUF258 PF03193.11 KFH47722.1 - 0.093 11.9 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 KFH47722.1 - 0.13 12.1 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 KFH47722.1 - 0.64 8.8 3.0 0.32 9.8 0.3 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Glyco_hydro_47 PF01532.15 KFH47723.1 - 1.2e-133 446.0 0.0 1.5e-133 445.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 p450 PF00067.17 KFH47724.1 - 7.9e-57 192.7 0.0 1.1e-56 192.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Flavoprotein PF02441.14 KFH47726.1 - 2.8e-39 133.7 0.1 3.6e-39 133.3 0.1 1.1 1 0 0 1 1 1 1 Flavoprotein Ank_2 PF12796.2 KFH47727.1 - 1.3e-29 102.3 0.0 3.8e-14 52.7 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFH47727.1 - 3.1e-27 92.9 2.8 8.6e-09 34.7 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 KFH47727.1 - 1.8e-20 72.9 0.4 1.7e-10 41.1 0.0 5.1 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFH47727.1 - 1.5e-18 66.3 0.4 8.9e-11 41.6 0.1 4.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFH47727.1 - 1.3e-17 62.1 0.2 3.2e-05 23.7 0.0 5.6 5 0 0 5 5 5 2 Ankyrin repeat NACHT PF05729.7 KFH47727.1 - 9.4e-08 31.8 0.0 2e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KFH47727.1 - 2.4e-06 27.6 0.1 5.7e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFH47727.1 - 0.014 15.5 0.0 0.039 14.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 KFH47727.1 - 0.097 12.1 0.2 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 KFH47727.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.1 KFH47727.1 - 0.11 12.2 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Viral_helicase1 PF01443.13 KFH47727.1 - 0.16 11.4 0.0 0.36 10.2 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase FNIP PF05725.7 KFH47727.1 - 0.17 11.8 0.0 0.51 10.3 0.0 1.8 2 0 0 2 2 2 0 FNIP Repeat AAA_18 PF13238.1 KFH47727.1 - 0.19 12.0 0.4 0.57 10.4 0.1 2.0 2 1 0 2 2 2 0 AAA domain MAS20 PF02064.10 KFH47728.1 - 3.1e-13 49.6 0.4 7e-13 48.5 0.2 1.4 1 1 0 1 1 1 1 MAS20 protein import receptor DUF533 PF04391.7 KFH47728.1 - 0.0029 16.9 1.0 0.0035 16.7 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF533) Rhabdo_ncap PF00945.13 KFH47728.1 - 0.018 13.6 0.7 0.022 13.3 0.5 1.0 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein RibD_C PF01872.12 KFH47730.1 - 1.2e-33 116.4 0.0 1.4e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain Fungal_trans PF04082.13 KFH47731.1 - 7.4e-13 47.9 0.4 1.4e-12 47.0 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 KFH47731.1 - 8e-07 29.0 10.1 1.3e-05 25.2 0.8 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFH47731.1 - 3e-05 24.0 14.2 0.0015 18.7 4.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 KFH47731.1 - 0.0016 18.4 3.8 0.003 17.6 2.6 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 KFH47731.1 - 0.023 15.0 16.8 0.051 13.9 4.7 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-BED PF02892.10 KFH47731.1 - 5.2 6.9 8.4 1.8 8.3 1.1 2.5 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_jaz PF12171.3 KFH47731.1 - 9.4 6.5 7.4 8 6.7 0.5 2.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Glyco_hydro_76 PF03663.9 KFH47733.1 - 1.3e-55 189.2 10.4 1.6e-55 189.0 7.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KFH47733.1 - 0.00012 21.2 4.5 0.055 12.4 0.0 3.1 2 2 1 3 3 3 2 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 KFH47733.1 - 0.0037 15.6 0.9 0.63 8.2 0.0 2.3 2 1 1 3 3 3 3 Putative glycosyl hydrolase of unknown function (DUF1680) Bromodomain PF00439.20 KFH47735.1 - 4.9e-33 112.9 0.1 2e-16 59.6 0.0 3.0 2 1 1 3 3 3 2 Bromodomain DUF2422 PF10337.4 KFH47736.1 - 1.6e-14 53.5 1.1 8.2e-08 31.4 4.0 4.3 2 2 2 4 4 4 3 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 KFH47736.1 - 1.1e-08 35.0 19.8 1.1e-08 35.0 13.8 2.8 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 KFH47736.1 - 9.9e-08 31.0 20.0 1.1e-05 24.3 11.0 2.3 2 0 0 2 2 2 2 Aluminium activated malate transporter HAD_2 PF13419.1 KFH47737.1 - 2.1e-32 112.7 0.1 2.5e-32 112.5 0.1 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFH47737.1 - 1.9e-05 24.2 0.0 3.3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KFH47737.1 - 0.0013 19.1 0.0 0.0025 18.2 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DASH_Dad4 PF08650.5 KFH47738.1 - 2.9e-14 52.7 1.4 3.1e-14 52.6 1.0 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 tRNA-synt_2b PF00587.20 KFH47739.1 - 1e-45 155.4 0.0 1.5e-45 154.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KFH47739.1 - 1.3e-08 34.7 0.0 2.8e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Hemerythrin PF01814.18 KFH47740.1 - 8.8e-10 38.8 0.6 1.2e-09 38.4 0.4 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain TAP42 PF04177.7 KFH47741.1 - 5.8e-89 298.3 0.0 6.5e-89 298.2 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family KBP_C PF12309.3 KFH47741.1 - 0.078 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 KIF-1 binding protein C terminal Actin PF00022.14 KFH47742.1 - 4.8e-17 61.4 0.0 3.5e-16 58.6 0.0 2.0 1 1 0 1 1 1 1 Actin Ion_trans PF00520.26 KFH47743.1 - 4.9e-05 22.6 14.8 0.0001 21.6 10.2 1.5 1 0 0 1 1 1 1 Ion transport protein DUF3592 PF12158.3 KFH47744.1 - 0.13 12.0 1.8 0.34 10.6 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3592) WD40 PF00400.27 KFH47745.1 - 3.9e-29 99.4 10.3 6.4e-09 35.3 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Got1 PF04178.7 KFH47746.1 - 3e-18 66.0 13.3 3.5e-18 65.8 9.2 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family YrhK PF14145.1 KFH47746.1 - 0.57 9.8 9.8 0.074 12.7 2.2 2.5 2 1 0 2 2 2 0 YrhK-like protein Methyltransf_31 PF13847.1 KFH47747.1 - 2.8e-06 26.9 0.0 4.2e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH47747.1 - 0.00039 20.8 0.0 0.016 15.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH47747.1 - 0.011 16.3 0.0 0.017 15.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KFH47747.1 - 0.058 13.8 0.0 0.12 12.8 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain CybS PF05328.7 KFH47748.1 - 1.8e-46 157.0 0.0 2.2e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 CybS Sdh_cyt PF01127.17 KFH47748.1 - 0.0053 16.5 1.0 0.19 11.5 0.1 2.2 1 1 1 2 2 2 2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Kinesin PF00225.18 KFH47749.1 - 1.5e-113 378.8 0.4 4.1e-113 377.4 0.2 1.8 1 0 0 1 1 1 1 Kinesin motor domain CENP-F_leu_zip PF10473.4 KFH47749.1 - 2.9 7.7 68.4 7.6 6.3 17.2 5.0 3 1 2 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MscL PF01741.13 KFH47751.1 - 1.1e-15 57.9 1.0 2.8e-15 56.5 0.7 1.6 1 1 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL C1_1 PF00130.17 KFH47751.1 - 0.0088 15.7 1.8 0.015 15.0 1.3 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_2 PF13240.1 KFH47751.1 - 0.027 13.9 0.5 0.043 13.3 0.4 1.3 1 0 0 1 1 1 0 zinc-ribbon domain DUF2339 PF10101.4 KFH47751.1 - 0.057 11.7 1.5 0.074 11.3 1.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) Bul1_N PF04425.7 KFH47753.1 - 3.5 6.0 9.1 7.1 5.0 6.3 1.4 1 0 0 1 1 1 0 Bul1 N terminus SH3_9 PF14604.1 KFH47754.1 - 1.3e-06 27.8 0.2 2.5e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFH47754.1 - 0.00064 19.0 0.1 0.0013 18.1 0.1 1.5 1 0 0 1 1 1 1 SH3 domain Podoplanin PF05808.6 KFH47754.1 - 0.0054 16.2 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 Podoplanin Glycophorin_A PF01102.13 KFH47754.1 - 0.0071 16.1 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Glycophorin A PLDc PF00614.17 KFH47755.1 - 4.4e-14 51.7 0.2 3e-06 26.8 0.0 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KFH47755.1 - 1.8e-12 47.0 0.0 1.8e-05 24.4 0.0 3.1 3 0 0 3 3 3 2 PLD-like domain TFIID-18kDa PF02269.11 KFH47756.1 - 9.8e-27 92.6 2.7 1.2e-26 92.3 0.1 2.3 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit SUR7 PF06687.7 KFH47757.1 - 9.5e-27 93.9 0.0 1.1e-26 93.6 0.0 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 KFH47757.1 - 0.00023 21.1 2.8 0.00023 21.1 1.9 1.5 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 Acyl_transf_3 PF01757.17 KFH47757.1 - 0.092 11.5 4.6 0.029 13.1 1.2 1.5 2 0 0 2 2 2 0 Acyltransferase family Claudin_2 PF13903.1 KFH47757.1 - 0.19 11.3 10.3 0.6 9.7 4.0 2.7 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Ank_2 PF12796.2 KFH47758.1 - 2.5e-83 274.4 0.2 1.2e-13 51.1 0.0 7.6 4 2 3 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KFH47758.1 - 1.1e-60 198.5 9.9 3.6e-05 23.3 0.0 16.0 17 0 0 17 17 17 14 Ankyrin repeat Ank_4 PF13637.1 KFH47758.1 - 2.3e-50 168.1 2.2 3.4e-07 30.5 0.0 12.7 6 5 7 13 13 13 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFH47758.1 - 4.8e-43 140.8 0.1 0.00097 19.1 0.0 14.5 15 0 0 15 15 15 11 Ankyrin repeat Ank_5 PF13857.1 KFH47758.1 - 1.6e-40 136.1 8.7 1.1e-06 28.6 0.0 11.3 4 3 9 13 13 13 11 Ankyrin repeats (many copies) Sec63 PF02889.11 KFH47759.1 - 8.9e-153 508.0 0.0 4.8e-98 328.2 0.1 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KFH47759.1 - 1.1e-53 181.2 0.4 2.8e-28 98.4 0.2 3.4 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KFH47759.1 - 3.9e-18 65.0 0.0 1.3e-07 31.3 0.0 3.8 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 KFH47759.1 - 1.1e-15 57.9 0.0 1.7e-06 27.9 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KFH47759.1 - 1.7e-08 34.6 0.0 0.012 15.7 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KFH47759.1 - 3.6e-06 26.6 0.5 0.1 12.3 0.0 3.3 3 0 0 3 3 3 2 Part of AAA domain AAA_25 PF13481.1 KFH47759.1 - 0.0073 15.7 0.2 4.4 6.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 KFH47759.1 - 0.015 14.6 0.2 16 4.8 0.0 3.7 4 0 0 4 4 4 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 KFH47759.1 - 0.022 14.2 0.0 6.6 6.1 0.0 3.3 3 0 0 3 3 3 0 FtsK/SpoIIIE family PhoH PF02562.11 KFH47759.1 - 0.025 13.8 0.0 2.3 7.3 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein AAA_10 PF12846.2 KFH47759.1 - 0.039 13.3 0.0 16 4.7 0.0 3.4 4 0 0 4 4 4 0 AAA-like domain SMC_N PF02463.14 KFH47760.1 - 9e-66 221.2 22.0 4.4e-64 215.7 15.3 3.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KFH47760.1 - 2.3e-22 79.1 1.6 7.7e-22 77.5 0.3 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KFH47760.1 - 3.4e-14 53.4 1.3 4e-06 27.0 0.1 3.4 3 0 0 3 3 3 2 AAA domain MscS_porin PF12795.2 KFH47760.1 - 5.7e-08 32.3 31.8 5.7e-08 32.3 22.1 6.2 2 2 2 5 5 5 1 Mechanosensitive ion channel porin domain AAA_29 PF13555.1 KFH47760.1 - 6e-05 22.4 0.0 0.00014 21.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 KFH47760.1 - 0.002 16.7 24.3 0.002 16.7 16.8 6.4 3 2 3 6 6 6 3 AAA domain Reo_sigmaC PF04582.7 KFH47760.1 - 0.01 15.0 38.9 0.011 14.9 0.8 6.4 3 2 3 8 8 8 0 Reovirus sigma C capsid protein YbbR PF07949.7 KFH47760.1 - 0.02 15.0 0.2 0.31 11.1 0.0 3.1 2 0 0 2 2 2 0 YbbR-like protein ABC_tran PF00005.22 KFH47760.1 - 0.039 14.2 0.0 0.039 14.2 0.0 5.9 4 2 0 4 4 4 0 ABC transporter DNA_topoisoIV PF00521.15 KFH47761.1 - 2.5e-117 392.3 0.0 6e-117 391.0 0.0 1.6 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 KFH47761.1 - 1.4e-32 112.2 2.3 3.4e-32 111.0 1.6 1.5 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 KFH47761.1 - 2e-13 50.1 0.1 2.3e-12 46.7 0.0 2.8 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 KFH47761.1 - 2.7e-09 36.7 0.1 6.1e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3112 PF11309.3 KFH47762.1 - 6.9e-43 146.2 11.4 1.6e-40 138.4 0.5 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) UPF0220 PF05255.6 KFH47762.1 - 0.0047 16.1 3.7 0.0087 15.3 2.5 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) MFS_Mycoplasma PF07672.8 KFH47762.1 - 1.4 8.0 10.0 0.11 11.6 3.2 1.7 2 0 0 2 2 2 0 Mycoplasma MFS transporter SUN PF03856.8 KFH47763.1 - 1.6e-73 247.0 11.3 2.1e-73 246.7 7.8 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) IER PF05760.7 KFH47763.1 - 2.1 8.1 14.4 3.9 7.2 10.0 1.3 1 0 0 1 1 1 0 Immediate early response protein (IER) DUF572 PF04502.8 KFH47763.1 - 2.9 7.0 10.0 4 6.5 7.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DAO PF01266.19 KFH47764.1 - 1.2e-54 185.5 4.6 1.4e-54 185.4 3.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KFH47764.1 - 6.7e-06 26.3 0.1 0.00018 21.6 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFH47764.1 - 9.7e-06 25.5 0.5 2.5e-05 24.1 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Mqo PF06039.10 KFH47764.1 - 0.001 17.3 0.0 0.23 9.5 0.0 2.2 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) Pyr_redox_2 PF07992.9 KFH47764.1 - 0.022 14.6 0.2 0.1 12.4 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFH47764.1 - 0.05 12.7 0.8 0.088 11.8 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.7 KFH47764.1 - 0.076 11.9 0.1 0.14 11.0 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 KFH47764.1 - 0.081 11.9 0.3 0.48 9.4 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.13 KFH47764.1 - 0.099 12.6 0.1 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Pribosyltran PF00156.22 KFH47765.1 - 1.1e-17 63.9 0.7 1.9e-17 63.1 0.5 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KFH47765.1 - 0.075 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Myb_Cef PF11831.3 KFH47766.1 - 4.3e-57 193.0 6.6 4.3e-57 193.0 4.6 3.5 4 0 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 KFH47766.1 - 2.2e-21 75.6 3.8 4.9e-10 39.3 0.2 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFH47766.1 - 3.3e-20 71.9 9.3 6.5e-15 54.9 2.3 3.5 2 1 1 3 3 3 2 Myb-like DNA-binding domain Thiolase_N PF00108.18 KFH47768.1 - 6.6e-91 303.9 0.5 1.1e-90 303.1 0.3 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KFH47768.1 - 2.1e-38 130.4 1.3 2.1e-38 130.4 0.9 2.3 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KFH47768.1 - 6.4e-05 22.5 2.8 0.00019 21.0 0.9 2.4 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain HSP70 PF00012.15 KFH47769.1 - 1.2e-266 885.3 16.0 1.4e-266 885.1 11.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFH47769.1 - 3e-14 52.3 5.7 2.2e-12 46.2 1.5 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 KFH47769.1 - 7.1e-05 22.5 0.1 0.00025 20.7 0.0 2.0 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 KFH47769.1 - 0.068 13.0 11.1 5 6.9 2.5 4.5 2 1 0 3 3 3 0 Cell division protein FtsA DUF4363 PF14276.1 KFH47769.1 - 0.62 9.7 2.6 1.3 8.7 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) Spc97_Spc98 PF04130.8 KFH47770.1 - 1.5e-128 429.5 0.3 2e-128 429.0 0.2 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family TT_ORF2 PF02957.10 KFH47770.1 - 0.11 13.1 0.1 0.11 13.1 0.0 2.5 3 0 0 3 3 3 0 TT viral ORF2 Vps51 PF08700.6 KFH47771.1 - 1.2e-16 60.2 2.5 4.4e-16 58.4 1.7 2.0 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.6 KFH47771.1 - 0.0012 18.7 0.9 0.072 12.9 0.0 2.7 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2383 PF09537.5 KFH47771.1 - 0.013 15.7 4.7 1.9 8.7 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Laminin_B PF00052.13 KFH47771.1 - 0.022 14.3 0.5 0.065 12.8 0.1 2.0 2 1 0 2 2 2 0 Laminin B (Domain IV) Atg14 PF10186.4 KFH47771.1 - 0.97 8.3 11.1 0.7 8.7 2.2 2.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Ada3 PF10198.4 KFH47772.1 - 2.3e-42 143.8 0.0 6.7e-42 142.3 0.0 1.8 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 DUF4527 PF15030.1 KFH47772.1 - 0.083 12.1 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) Ribosomal_60s PF00428.14 KFH47772.1 - 0.16 12.3 4.8 0.52 10.7 3.3 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein DASH_Ask1 PF08655.5 KFH47773.1 - 1.5e-22 79.1 0.0 2.8e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 Fungal_trans_2 PF11951.3 KFH47774.1 - 1.1e-15 57.1 1.7 3.6e-09 35.7 0.1 2.9 2 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH47774.1 - 4.1e-08 32.9 11.6 7e-08 32.2 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFH47774.1 - 0.00075 18.4 0.1 0.0023 16.8 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Ist1 PF03398.9 KFH47775.1 - 2.8e-62 208.9 0.4 3.6e-62 208.6 0.3 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DUF1479 PF07350.7 KFH47776.1 - 6.1e-164 545.4 0.0 7.1e-164 545.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 KFH47776.1 - 0.016 15.2 0.3 5.8 6.8 0.0 2.5 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) GTP_EFTU PF00009.22 KFH47777.1 - 1.4e-50 171.3 0.0 2.4e-50 170.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 KFH47777.1 - 1.5e-19 69.5 0.0 3.3e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 KFH47777.1 - 4.6e-14 52.0 0.0 4.8e-13 48.7 0.0 2.3 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KFH47777.1 - 0.00011 22.2 0.0 0.00037 20.5 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 zf-RING_2 PF13639.1 KFH47778.1 - 6.8e-10 38.6 7.4 1.2e-09 37.8 5.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFH47778.1 - 6e-05 23.0 3.8 0.00015 21.8 2.7 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFH47778.1 - 0.00013 21.5 6.4 0.00021 20.8 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFH47778.1 - 0.00032 20.3 7.1 0.0005 19.7 4.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFH47778.1 - 0.00033 20.6 7.7 0.0006 19.7 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFH47778.1 - 0.012 15.4 3.3 0.024 14.4 2.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Vps39_2 PF10367.4 KFH47778.1 - 0.032 14.3 0.1 0.032 14.3 0.1 1.8 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 DUF1049 PF06305.6 KFH47778.1 - 0.035 13.5 0.4 0.035 13.5 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) zf-C3HC4_3 PF13920.1 KFH47778.1 - 0.05 13.2 9.1 0.085 12.5 6.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3955 PF13127.1 KFH47778.1 - 0.11 12.1 0.7 0.17 11.4 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3955) stn_TNFRSF12A PF12191.3 KFH47778.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain zf-C3HC4_4 PF15227.1 KFH47778.1 - 6.9 6.6 9.1 13 5.7 6.3 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.24 KFH47778.1 - 8.3 6.1 7.8 15 5.3 5.4 1.4 1 0 0 1 1 1 0 PHD-finger DUF663 PF04950.7 KFH47779.1 - 9.6e-90 300.5 0.0 9.6e-90 300.5 0.0 2.4 3 0 0 3 3 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KFH47779.1 - 8e-28 95.8 0.0 6.4e-26 89.7 0.0 2.8 2 0 0 2 2 2 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 KFH47779.1 - 4.5e-06 26.2 0.0 0.00074 18.9 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KFH47779.1 - 4.9e-06 26.7 0.0 1.7e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFH47779.1 - 6.5e-06 26.2 0.7 2.5e-05 24.3 0.0 2.4 2 0 0 2 2 1 1 AAA ATPase domain MMR_HSR1 PF01926.18 KFH47779.1 - 0.00014 21.7 0.0 0.00037 20.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.7 KFH47779.1 - 0.00022 20.9 0.0 0.00046 19.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 KFH47779.1 - 0.00046 19.8 0.1 0.0012 18.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 KFH47779.1 - 0.00049 20.3 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 KFH47779.1 - 0.00065 20.0 0.0 0.00065 20.0 0.0 2.7 3 0 0 3 3 2 1 ABC transporter AAA_17 PF13207.1 KFH47779.1 - 0.00079 20.2 0.0 0.00079 20.2 0.0 4.8 4 1 0 5 5 2 1 AAA domain MobB PF03205.9 KFH47779.1 - 0.00087 19.0 0.0 0.0031 17.2 0.0 2.0 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 KFH47779.1 - 0.001 18.5 0.0 0.0028 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFH47779.1 - 0.0011 18.9 0.0 0.0058 16.5 0.0 2.3 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 KFH47779.1 - 0.0013 19.2 0.0 0.0041 17.6 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_14 PF13173.1 KFH47779.1 - 0.0034 17.2 0.0 0.0092 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KFH47779.1 - 0.0051 16.2 0.0 0.0051 16.2 0.0 2.3 3 0 0 3 3 3 1 AAA-like domain PduV-EutP PF10662.4 KFH47779.1 - 0.0056 16.1 0.0 0.017 14.6 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 KFH47779.1 - 0.0074 16.5 0.0 0.0074 16.5 0.0 5.3 3 1 5 8 8 7 1 AAA domain NTPase_1 PF03266.10 KFH47779.1 - 0.0078 15.9 0.2 0.017 14.8 0.1 1.6 1 0 0 1 1 1 1 NTPase AAA_24 PF13479.1 KFH47779.1 - 0.0097 15.5 0.1 0.029 13.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 KFH47779.1 - 0.01 15.2 0.4 0.93 8.9 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.17 KFH47779.1 - 0.011 15.9 0.0 0.027 14.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase cobW PF02492.14 KFH47779.1 - 0.015 14.7 0.0 0.032 13.6 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 KFH47779.1 - 0.015 14.4 0.0 0.049 12.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 NB-ARC PF00931.17 KFH47779.1 - 0.017 14.0 0.0 0.035 12.9 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.9 KFH47779.1 - 0.063 13.0 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.1 KFH47779.1 - 0.32 10.9 3.9 0.46 10.3 0.0 2.9 3 1 1 4 4 3 0 AAA domain Asp_protease PF09668.5 KFH47780.1 - 1.2e-58 196.0 0.2 1.9e-58 195.4 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 KFH47780.1 - 6.6e-12 45.7 0.0 2.3e-11 44.0 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease UBA PF00627.26 KFH47780.1 - 3e-09 36.4 0.5 7.2e-09 35.2 0.4 1.7 1 0 0 1 1 1 1 UBA/TS-N domain ubiquitin PF00240.18 KFH47780.1 - 5.5e-09 35.3 0.1 1.1e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family gag-asp_proteas PF13975.1 KFH47780.1 - 1.5e-07 31.1 0.0 3.3e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 KFH47780.1 - 1.5e-06 28.0 0.0 4.9e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 KFH47780.1 - 1.8e-06 27.9 0.0 2.8e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Rad60-SLD PF11976.3 KFH47780.1 - 0.00044 19.8 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_4 PF14555.1 KFH47780.1 - 0.039 13.4 0.1 0.092 12.2 0.1 1.6 1 0 0 1 1 1 0 UBA-like domain bZIP_1 PF00170.16 KFH47781.1 - 1.5e-06 28.0 10.0 1.5e-06 28.0 6.9 1.6 2 0 0 2 2 2 1 bZIP transcription factor CTP_transf_3 PF02348.14 KFH47781.1 - 4 6.9 6.1 1.1 8.8 1.4 1.9 1 1 0 2 2 2 0 Cytidylyltransferase FPN1 PF06963.7 KFH47782.1 - 6.2e-119 397.2 16.6 7.1e-119 397.0 11.5 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Tyr-DNA_phospho PF06087.7 KFH47783.1 - 3.7e-131 437.8 0.0 4.2e-131 437.6 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 KFH47783.1 - 0.00055 19.6 0.0 0.43 10.3 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain Het-C PF07217.6 KFH47784.1 - 2.8e-254 844.9 0.0 2.8e-254 844.9 0.0 1.5 2 0 0 2 2 2 1 Heterokaryon incompatibility protein Het-C Pox_VLTF3 PF04947.9 KFH47784.1 - 0.035 13.6 0.1 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 Poxvirus Late Transcription Factor VLTF3 like ResIII PF04851.10 KFH47785.1 - 3.3e-25 88.9 0.0 6.4e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KFH47785.1 - 9.4e-16 57.4 0.0 3e-15 55.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFH47785.1 - 2e-12 46.9 0.0 3.6e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.4 KFH47785.1 - 0.003 16.5 0.0 0.0052 15.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 KFH47785.1 - 0.0058 16.2 0.1 0.32 10.5 0.0 2.6 1 1 1 2 2 2 1 AAA domain Flavi_DEAD PF07652.9 KFH47785.1 - 0.01 15.5 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain DUF3072 PF11272.3 KFH47785.1 - 0.016 14.8 0.0 0.042 13.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) SNF2_N PF00176.18 KFH47785.1 - 0.077 11.7 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_22 PF13401.1 KFH47785.1 - 0.11 12.6 0.1 0.35 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain GDI PF00996.13 KFH47786.1 - 1.8e-181 603.2 0.0 2.1e-181 603.0 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 KFH47786.1 - 0.073 13.1 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DnaJ PF00226.26 KFH47787.1 - 2e-22 78.6 1.3 3.8e-22 77.7 0.9 1.5 1 0 0 1 1 1 1 DnaJ domain HIT PF01230.18 KFH47788.1 - 1.8e-17 63.6 0.0 2.4e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 HIT domain CwfJ_C_1 PF04677.10 KFH47788.1 - 0.0096 15.5 0.4 1.4 8.6 0.0 2.8 3 0 0 3 3 3 1 Protein similar to CwfJ C-terminus 1 DcpS_C PF11969.3 KFH47788.1 - 0.01 16.0 0.0 0.016 15.4 0.0 1.2 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding Eaf7 PF07904.8 KFH47790.1 - 3.1e-28 97.5 0.2 6.2e-28 96.6 0.1 1.5 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 PAP1 PF08601.5 KFH47790.1 - 0.054 13.1 4.8 0.079 12.6 3.3 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 AlkA_N PF06029.6 KFH47790.1 - 0.057 13.4 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 AlkA N-terminal domain MFMR PF07777.6 KFH47790.1 - 4.4 7.1 11.6 10 5.9 8.0 1.5 1 0 0 1 1 1 0 G-box binding protein MFMR DUF2201_N PF13203.1 KFH47790.1 - 6.3 5.8 9.7 11 5.1 6.7 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain NOT2_3_5 PF04153.13 KFH47791.1 - 3.6e-25 88.3 5.5 6.3e-12 45.5 0.0 2.3 2 0 0 2 2 2 2 NOT2 / NOT3 / NOT5 family TPR_11 PF13414.1 KFH47792.1 - 2e-11 43.3 3.4 1.5e-10 40.6 0.1 2.9 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 KFH47792.1 - 5.1e-07 29.1 4.7 0.29 11.1 0.1 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KFH47792.1 - 4.8e-06 25.9 3.6 0.67 9.6 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFH47792.1 - 0.00094 19.4 3.0 0.0011 19.2 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 KFH47792.1 - 0.003 17.6 0.1 0.0072 16.4 0.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF2335 PF10097.4 KFH47792.1 - 0.9 9.2 4.7 2.1 8.0 3.2 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) eIF-4B PF06273.6 KFH47793.1 - 0.33 9.6 4.0 0.45 9.2 2.8 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Clat_adaptor_s PF01217.15 KFH47794.1 - 1.4e-56 190.1 1.6 1.6e-56 189.9 1.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Pterin_4a PF01329.14 KFH47795.1 - 3.5e-29 100.3 0.3 1.3e-28 98.6 0.0 1.8 2 0 0 2 2 2 1 Pterin 4 alpha carbinolamine dehydratase Fungal_trans PF04082.13 KFH47796.1 - 2.1e-35 121.8 0.0 5.5e-35 120.5 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH47796.1 - 3.9e-09 36.2 9.3 6.3e-09 35.6 6.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribonuclease_T2 PF00445.13 KFH47797.1 - 3.6e-26 91.9 0.4 5.8e-26 91.2 0.2 1.4 1 0 0 1 1 1 1 Ribonuclease T2 family NCA2 PF08637.5 KFH47798.1 - 1.4e-87 293.3 0.0 2.2e-87 292.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 TMEM171 PF15471.1 KFH47798.1 - 0.0068 15.2 0.1 0.014 14.2 0.1 1.4 1 0 0 1 1 1 1 Transmembrane protein family 171 SLD3 PF08639.5 KFH47798.1 - 0.27 9.8 0.4 0.43 9.1 0.3 1.2 1 0 0 1 1 1 0 DNA replication regulator SLD3 Myb_DNA-bind_3 PF12776.2 KFH47799.1 - 0.007 16.9 1.6 0.015 15.9 1.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain HMG_box_5 PF14887.1 KFH47799.1 - 0.074 12.8 1.7 0.18 11.5 1.2 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box 5 DUF1014 PF06244.7 KFH47800.1 - 4e-21 75.4 11.3 1.1e-20 74.0 7.8 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) HNF-1_N PF04814.8 KFH47800.1 - 8.7 6.4 9.3 0.89 9.6 3.0 1.8 2 1 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Fungal_trans_2 PF11951.3 KFH47801.1 - 2e-05 23.3 0.0 3.5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 KFH47802.1 - 5.4e-11 41.8 0.0 9.4e-11 41.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tfb4 PF03850.9 KFH47802.1 - 0.08 12.1 0.1 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Transcription factor Tfb4 CDO_I PF05995.7 KFH47804.1 - 3.3e-39 133.8 0.0 3.8e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 KFH47804.1 - 0.0023 17.3 0.2 0.0057 16.0 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1637) Mob1_phocein PF03637.12 KFH47805.1 - 6.2e-27 94.3 0.1 9.6e-27 93.7 0.1 1.2 1 0 0 1 1 1 1 Mob1/phocein family Pribosyltran PF00156.22 KFH47806.1 - 9.2e-20 70.6 0.0 1.3e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KFH47806.1 - 0.0003 20.0 0.1 0.00054 19.2 0.0 1.4 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase PRTase_3 PF15610.1 KFH47806.1 - 0.054 12.4 0.0 0.07 12.0 0.0 1.1 1 0 0 1 1 1 0 PRTase ComF-like Semialdhyde_dh PF01118.19 KFH47807.1 - 1.6e-29 102.6 0.0 4.1e-29 101.3 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.13 KFH47807.1 - 4.6e-06 26.6 0.0 8.3e-06 25.7 0.0 1.4 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain NAD_binding_10 PF13460.1 KFH47807.1 - 0.00012 22.2 0.0 0.00023 21.2 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 KFH47807.1 - 0.041 13.8 0.0 0.098 12.5 0.0 1.8 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 KFH47807.1 - 0.078 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family PfkB PF00294.19 KFH47808.1 - 2.5e-51 174.6 0.0 3e-51 174.3 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase PCI PF01399.22 KFH47809.1 - 0.0022 18.2 0.0 3.2 8.1 0.0 3.0 3 0 0 3 3 3 2 PCI domain IBN_N PF03810.14 KFH47811.1 - 7e-14 51.4 0.2 9.3e-13 47.9 0.0 3.1 4 0 0 4 4 4 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KFH47811.1 - 0.00043 20.2 0.3 0.0043 16.9 0.1 2.8 2 0 0 2 2 2 1 Exportin 1-like protein Cse1 PF08506.5 KFH47811.1 - 0.00087 17.9 0.2 0.017 13.6 0.0 2.3 2 0 0 2 2 2 1 Cse1 Radical_SAM PF04055.16 KFH47813.1 - 2.6e-26 92.7 0.1 6.8e-26 91.4 0.1 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 KFH47813.1 - 4.8e-23 81.0 0.0 1e-22 79.9 0.0 1.6 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 KFH47813.1 - 2.8e-08 33.8 1.3 5.7e-06 26.3 0.0 3.4 2 1 0 3 3 3 1 Flavodoxin MFS_1_like PF12832.2 KFH47814.1 - 1.4e-07 31.1 0.1 5e-06 26.2 0.0 4.1 5 0 0 5 5 5 2 MFS_1 like family Transp_cyt_pur PF02133.10 KFH47815.1 - 1.3e-27 96.4 35.1 2.4e-26 92.2 24.3 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Glyco_hydro_76 PF03663.9 KFH47816.1 - 2.4e-124 415.4 2.7 2.9e-124 415.2 1.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KFH47816.1 - 0.0012 17.9 2.8 0.73 8.8 0.0 2.9 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 KFH47816.1 - 0.0057 14.9 0.1 0.33 9.1 0.0 2.3 2 1 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) Aminotran_1_2 PF00155.16 KFH47817.1 - 8.4e-64 215.7 0.0 1e-63 215.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.8 KFH47817.1 - 0.046 12.3 0.0 0.069 11.7 0.0 1.2 1 0 0 1 1 1 0 Allinase Med21 PF11221.3 KFH47818.1 - 2.1e-42 144.5 5.9 2.3e-42 144.3 4.1 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Cast PF10174.4 KFH47818.1 - 0.0012 16.9 4.8 0.0017 16.5 3.3 1.4 1 1 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone GAS PF13851.1 KFH47818.1 - 0.0047 16.1 5.3 0.1 11.7 0.0 2.1 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding CtIP_N PF10482.4 KFH47818.1 - 0.0052 16.5 2.9 0.086 12.6 0.9 2.2 1 1 1 2 2 2 1 Tumour-suppressor protein CtIP N-terminal domain TMCO5 PF14992.1 KFH47818.1 - 0.0074 15.4 3.3 0.0082 15.3 2.3 1.1 1 0 0 1 1 1 1 TMCO5 family MAD PF05557.8 KFH47818.1 - 0.0082 14.3 2.6 0.0094 14.1 1.8 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Spc7 PF08317.6 KFH47818.1 - 0.037 12.6 2.6 0.04 12.5 1.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Med9 PF07544.8 KFH47818.1 - 0.059 13.1 1.0 0.059 13.1 0.7 2.7 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF4515 PF14988.1 KFH47818.1 - 0.12 12.0 7.0 0.017 14.8 2.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) DUF3829 PF12889.2 KFH47818.1 - 0.3 10.2 2.3 0.45 9.6 1.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3829) Fib_alpha PF08702.5 KFH47818.1 - 0.36 10.9 3.5 0.36 10.9 0.9 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family APG6 PF04111.7 KFH47818.1 - 0.58 9.1 5.6 0.66 8.9 3.9 1.3 1 1 0 1 1 1 0 Autophagy protein Apg6 CENP-Q PF13094.1 KFH47818.1 - 0.73 9.8 7.7 0.48 10.4 4.1 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF16 PF01519.11 KFH47818.1 - 0.88 9.8 4.4 1.2 9.4 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 IncA PF04156.9 KFH47818.1 - 1.1 8.7 11.0 0.16 11.5 4.7 1.7 1 1 1 2 2 2 0 IncA protein TMF_DNA_bd PF12329.3 KFH47818.1 - 1.2 9.0 9.6 0.59 9.9 5.1 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Maf PF02545.9 KFH47819.1 - 1.6e-43 148.1 0.0 2e-43 147.8 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein ubiquitin PF00240.18 KFH47820.1 - 9.5e-20 69.7 0.1 1.7e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 KFH47820.1 - 3.1e-09 36.4 0.0 3.1e-09 36.4 0.0 3.2 4 0 0 4 4 4 1 UBA/TS-N domain Rad60-SLD PF11976.3 KFH47820.1 - 1.5e-06 27.7 0.1 2.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 KFH47820.1 - 2.9e-05 23.8 0.0 6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KFH47820.1 - 0.096 12.9 0.2 0.49 10.6 0.1 2.1 1 1 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.4 KFH47820.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2376 PF09550.5 KFH47820.1 - 3.1 8.0 5.1 3.6 7.8 0.3 3.0 3 0 0 3 3 3 0 Conserved hypothetical phage protein (DUF2376) MatE PF01554.13 KFH47821.1 - 1.8e-52 177.2 27.4 7e-29 100.5 8.0 2.4 2 0 0 2 2 2 2 MatE RabGAP-TBC PF00566.13 KFH47822.1 - 3.5e-47 160.6 0.0 9.7e-47 159.1 0.0 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF2782 PF11191.3 KFH47823.1 - 0.084 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) Zn_clus PF00172.13 KFH47824.1 - 5.5e-07 29.3 10.4 9.6e-07 28.6 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFH47824.1 - 0.00022 19.9 0.5 0.00022 19.9 0.4 1.6 1 1 1 2 2 2 1 Fungal specific transcription factor domain SR-25 PF10500.4 KFH47824.1 - 0.11 11.9 4.3 0.17 11.3 3.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Actin PF00022.14 KFH47825.1 - 1.3e-49 168.7 0.0 7.9e-24 83.8 0.0 3.0 2 1 0 2 2 2 2 Actin OmpH PF03938.9 KFH47825.1 - 0.0026 17.6 1.7 0.0026 17.6 1.1 3.3 3 0 0 3 3 3 1 Outer membrane protein (OmpH-like) MreB_Mbl PF06723.8 KFH47825.1 - 0.033 12.8 0.0 1.1 7.7 0.0 2.3 2 0 0 2 2 2 0 MreB/Mbl protein HLH PF00010.21 KFH47826.1 - 5.4e-06 26.0 0.0 9.5e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Glyoxalase PF00903.20 KFH47826.1 - 0.032 14.2 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FAD_binding_3 PF01494.14 KFH47827.1 - 1.4e-24 86.8 0.8 2.3e-16 59.8 0.2 2.8 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KFH47827.1 - 7.9e-07 29.0 0.0 1.7e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFH47827.1 - 6.6e-06 25.2 0.0 0.00039 19.4 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFH47827.1 - 6.4e-05 21.9 0.0 0.00014 20.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KFH47827.1 - 0.0035 17.7 0.0 0.025 14.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFH47827.1 - 0.0048 16.7 0.0 0.009 15.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFH47827.1 - 0.0057 15.1 0.0 0.011 14.1 0.0 1.4 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 KFH47827.1 - 0.0067 15.5 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.19 KFH47827.1 - 0.0096 15.0 0.0 0.12 11.4 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 KFH47827.1 - 0.015 14.2 0.0 0.07 12.0 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 KFH47827.1 - 0.028 14.1 0.0 0.75 9.5 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 KFH47827.1 - 0.054 13.1 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KFH47827.1 - 0.064 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 KFH47827.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain UQ_con PF00179.21 KFH47828.1 - 4.8e-52 175.1 0.1 5.5e-52 174.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFH47828.1 - 1.5e-06 27.9 0.0 1.7e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFH47828.1 - 0.0072 16.2 0.2 0.016 15.0 0.1 1.6 1 1 0 1 1 1 1 RWD domain DcpS_C PF11969.3 KFH47830.1 - 3.5e-29 101.3 0.0 1.5e-28 99.3 0.0 1.9 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 KFH47830.1 - 2.8e-25 88.8 0.0 4.5e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal 2OG-FeII_Oxy_2 PF13532.1 KFH47831.1 - 1.9e-33 115.9 0.0 2.5e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.7 KFH47831.1 - 2.4e-09 36.9 6.1 4.5e-09 36.1 4.2 1.4 1 0 0 1 1 1 1 GRF zinc finger 2OG-FeII_Oxy PF03171.15 KFH47831.1 - 0.002 18.3 0.0 0.0048 17.1 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CUE PF02845.11 KFH47831.1 - 0.038 13.4 0.0 0.069 12.6 0.0 1.4 1 0 0 1 1 1 0 CUE domain YL1_C PF08265.6 KFH47832.1 - 3.8e-16 58.3 0.1 6e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain CTD PF12815.2 KFH47832.1 - 0.002 18.5 4.3 0.0028 18.0 3.0 1.3 1 0 0 1 1 1 1 Spt5 C-terminal nonapeptide repeat binding Spt4 p450 PF00067.17 KFH47833.1 - 8e-56 189.4 0.0 1.1e-55 189.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LCM PF04072.9 KFH47835.1 - 1.9e-20 73.2 0.0 1.1e-19 70.6 0.0 2.0 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase priB_priC PF07445.7 KFH47836.1 - 0.0063 16.0 2.3 0.012 15.0 1.6 1.4 1 0 0 1 1 1 1 Primosomal replication protein priB and priC DUF2046 PF09755.4 KFH47836.1 - 0.07 12.0 2.1 0.14 10.9 1.5 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) Asparaginase_II PF06089.7 KFH47836.1 - 0.33 9.5 2.9 0.2 10.3 0.2 1.7 2 0 0 2 2 2 0 L-asparaginase II PEGSRP PF07623.6 KFH47836.1 - 8 5.8 11.8 6.9 6.0 2.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1584) DEAD PF00270.24 KFH47838.1 - 1e-40 138.9 0.1 1.5e-40 138.4 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFH47838.1 - 6.3e-22 77.2 0.1 1.8e-21 75.8 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KFH47838.1 - 0.041 14.0 0.1 0.12 12.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 KFH47838.1 - 0.045 13.5 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Profilin PF00235.14 KFH47839.1 - 1.6e-30 105.6 0.0 1.8e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 Profilin ADH_zinc_N PF00107.21 KFH47840.1 - 1.2e-34 118.7 0.3 2e-34 117.9 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFH47840.1 - 5.3e-09 37.0 0.2 1.2e-08 35.9 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFH47840.1 - 3.5e-06 26.7 0.0 1e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 KFH47840.1 - 0.001 19.0 0.2 0.0018 18.2 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.16 KFH47840.1 - 0.0024 17.4 2.3 0.28 10.7 1.0 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Terpene_synth_C PF03936.11 KFH47841.1 - 7.2e-10 38.5 0.2 1.3e-09 37.6 0.2 1.4 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain Thioredoxin PF00085.15 KFH47842.1 - 3.3e-41 139.1 0.0 4.2e-27 93.8 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 KFH47842.1 - 2.8e-12 46.8 0.0 6.5e-06 26.0 0.0 3.4 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KFH47842.1 - 3e-08 33.8 1.5 0.00019 21.5 0.1 4.3 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KFH47842.1 - 7.4e-08 32.4 0.4 0.00017 21.6 0.0 4.0 4 0 0 4 4 4 1 Thioredoxin-like Thioredoxin_7 PF13899.1 KFH47842.1 - 0.00013 21.9 0.0 0.0018 18.2 0.0 2.8 2 0 0 2 2 2 1 Thioredoxin-like HyaE PF07449.6 KFH47842.1 - 0.00056 19.7 0.0 0.52 10.2 0.0 3.0 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.1 KFH47842.1 - 0.0024 17.4 0.6 0.99 8.9 0.0 3.0 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_3 PF13192.1 KFH47842.1 - 0.015 15.0 0.0 1 9.1 0.0 2.7 2 0 0 2 2 2 0 Thioredoxin domain TraF PF13728.1 KFH47842.1 - 0.021 14.2 0.0 0.073 12.5 0.0 2.0 2 0 0 2 2 2 0 F plasmid transfer operon protein AhpC-TSA PF00578.16 KFH47842.1 - 0.12 12.0 1.2 0.66 9.6 0.0 2.7 4 0 0 4 4 4 0 AhpC/TSA family Cupin_1 PF00190.17 KFH47843.1 - 4.5e-09 35.8 0.3 6.1e-09 35.4 0.2 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 KFH47843.1 - 0.097 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 Cupin domain DUF2415 PF10313.4 KFH47844.1 - 8.5e-12 44.5 0.0 1.8e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 KFH47844.1 - 0.17 11.8 0.8 15 5.6 0.0 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat Ras PF00071.17 KFH47845.1 - 7.5e-40 135.9 0.0 1.4e-37 128.5 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KFH47845.1 - 1.1e-17 64.6 0.0 1.5e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFH47845.1 - 6.1e-11 41.8 0.0 9.6e-11 41.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFH47845.1 - 0.0061 16.5 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KFH47845.1 - 0.014 14.5 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 KFH47845.1 - 0.032 14.3 0.0 0.062 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KFH47845.1 - 0.033 13.9 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Gtr1_RagA PF04670.7 KFH47845.1 - 0.042 12.9 0.0 0.061 12.4 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_33 PF13671.1 KFH47845.1 - 0.11 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KFH47845.1 - 0.12 11.9 0.2 0.24 10.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KFH47845.1 - 0.16 11.6 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.1 KFH47845.1 - 0.16 11.9 0.5 0.46 10.4 0.1 2.0 3 0 0 3 3 3 0 AAA domain INCENP_ARK-bind PF03941.10 KFH47846.1 - 7.4e-21 73.7 0.5 1.8e-20 72.5 0.4 1.7 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region Ycf1 PF05758.7 KFH47846.1 - 3.5 5.2 17.9 0.38 8.4 3.4 2.2 2 0 0 2 2 2 0 Ycf1 Longin PF13774.1 KFH47847.1 - 8e-15 54.1 0.0 1.4e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 KFH47847.1 - 3.5e-14 52.1 0.7 5.3e-14 51.5 0.5 1.2 1 0 0 1 1 1 1 Synaptobrevin SNF2_N PF00176.18 KFH47849.1 - 1e-65 221.4 0.0 1.4e-65 221.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFH47849.1 - 1.5e-10 40.7 0.0 3e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 KFH47849.1 - 4.9e-07 29.3 1.4 8.7e-07 28.5 1.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain DEAD PF00270.24 KFH47849.1 - 0.00035 20.1 0.0 0.00067 19.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_2 PF13639.1 KFH47849.1 - 0.002 17.8 1.7 0.0044 16.8 1.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KFH47849.1 - 0.0027 17.3 0.6 0.0065 16.1 0.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFH47849.1 - 0.0088 16.0 0.8 0.0088 16.0 0.5 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFH47849.1 - 0.011 15.4 2.3 0.029 14.0 1.6 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HIRAN PF08797.6 KFH47849.1 - 0.026 14.4 0.0 0.079 12.8 0.0 1.8 1 0 0 1 1 1 0 HIRAN domain zf-RING_UBOX PF13445.1 KFH47849.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger MOSC_N PF03476.11 KFH47850.1 - 2.4e-11 43.4 0.0 4.9e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 KFH47850.1 - 3.7e-08 32.9 0.1 3.6e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 MOSC domain Metallophos PF00149.23 KFH47851.1 - 5.2e-44 150.0 0.8 6.6e-44 149.7 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3419 PF11899.3 KFH47852.1 - 7.7e-155 515.2 0.1 1.2e-154 514.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 KFH47852.1 - 2.4e-12 46.8 0.0 1.1e-10 41.4 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH47852.1 - 2.6e-09 36.8 0.0 5.2e-08 32.6 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH47852.1 - 3.4e-09 37.2 0.0 1.3e-08 35.3 0.0 2.0 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH47852.1 - 2.4e-08 34.3 0.0 9.2e-08 32.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFH47852.1 - 3.5e-07 30.2 0.1 6.1e-05 23.0 0.0 3.4 3 1 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFH47852.1 - 8.3e-07 28.3 0.0 0.0036 16.4 0.0 2.9 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 KFH47852.1 - 8.7e-07 29.3 0.0 0.0056 17.1 0.0 4.0 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFH47852.1 - 1.5e-05 25.2 0.0 5.2e-05 23.5 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain PCMT PF01135.14 KFH47852.1 - 0.00019 21.0 0.0 0.00041 19.9 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 KFH47852.1 - 0.075 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_S13 PF00416.17 KFH47854.1 - 7e-42 142.2 1.6 8.4e-42 141.9 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 KFH47854.1 - 0.0091 14.5 0.0 0.0091 14.5 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Syntaxin-6_N PF09177.6 KFH47854.1 - 0.076 13.4 0.1 0.15 12.4 0.0 1.6 2 0 0 2 2 2 0 Syntaxin 6, N-terminal PP28 PF10252.4 KFH47854.1 - 0.09 12.8 1.0 0.2 11.6 0.7 1.6 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 ATP-synt PF00231.14 KFH47855.1 - 1.6e-71 241.0 1.7 1.8e-71 240.8 1.1 1.0 1 0 0 1 1 1 1 ATP synthase zf-HC5HC2H_2 PF13832.1 KFH47856.1 - 6.8e-19 67.8 1.9 6.8e-19 67.8 1.3 4.1 4 0 0 4 4 4 3 PHD-zinc-finger like domain BAH PF01426.13 KFH47856.1 - 7.3e-16 57.9 0.0 1.5e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 KFH47856.1 - 3.1e-13 49.1 46.5 1.3e-06 28.0 5.6 6.4 6 0 0 6 6 6 3 PHD-finger zf-HC5HC2H PF13771.1 KFH47856.1 - 2.5e-12 46.7 3.8 2.5e-12 46.7 2.6 4.6 5 0 0 5 5 5 1 PHD-like zinc-binding domain PHD_2 PF13831.1 KFH47856.1 - 2.5e-07 29.8 5.7 2.5e-07 29.8 3.9 5.3 6 0 0 6 6 6 2 PHD-finger Prok-RING_1 PF14446.1 KFH47856.1 - 0.00022 20.8 42.8 0.0095 15.6 4.2 4.4 5 0 0 5 5 5 3 Prokaryotic RING finger family 1 ELM2 PF01448.19 KFH47856.1 - 0.013 16.1 1.4 0.13 12.8 1.0 2.7 1 1 0 1 1 1 0 ELM2 domain OmpH PF03938.9 KFH47856.1 - 0.038 13.9 0.1 0.038 13.9 0.1 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Folliculin PF11704.3 KFH47856.1 - 0.22 11.0 0.0 0.5 9.9 0.0 1.5 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport TrkA_C PF02080.16 KFH47856.1 - 0.32 10.5 0.0 0.73 9.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-C domain Metallophos_2 PF12850.2 KFH47857.1 - 1.2e-06 28.4 0.0 2.6e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KFH47857.1 - 1.7e-05 24.2 1.7 4.4e-05 22.9 1.2 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Abhydrolase_6 PF12697.2 KFH47859.1 - 6e-20 72.1 14.3 6e-20 72.1 9.9 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH47859.1 - 1.3e-11 44.4 0.2 6.8e-11 42.1 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFH47859.1 - 1.2e-06 28.2 0.0 2.7e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KFH47859.1 - 3e-06 27.0 0.2 2.5e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Putative lysophospholipase Dus PF01207.12 KFH47860.1 - 9.5e-45 152.7 0.1 2e-44 151.6 0.1 1.6 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) NUDIX_2 PF13869.1 KFH47861.1 - 1.3e-79 265.8 0.0 1.6e-79 265.6 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase RhoGAP PF00620.22 KFH47862.1 - 3e-27 95.0 0.0 4.5e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain SBDS_C PF09377.5 KFH47863.1 - 1.7e-49 166.6 0.0 2.6e-49 166.0 0.0 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 KFH47863.1 - 1.1e-30 105.2 0.2 1.8e-30 104.5 0.1 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein K_channel_TID PF07941.6 KFH47863.1 - 1.2 9.4 4.6 9.3 6.5 0.4 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain tRNA-synt_His PF13393.1 KFH47865.1 - 1.1e-40 139.6 0.0 2.9e-34 118.5 0.0 2.2 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 KFH47865.1 - 1.9e-18 66.6 0.0 2.9e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KFH47865.1 - 2.2e-12 46.7 0.1 5.1e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 KFH47865.1 - 0.00027 19.8 0.2 0.011 14.5 0.0 2.6 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) HGTP_anticodon2 PF12745.2 KFH47865.1 - 0.098 11.7 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs ELO PF01151.13 KFH47866.1 - 9e-81 270.8 6.1 1.1e-80 270.6 4.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF3154 PF11351.3 KFH47866.1 - 0.84 9.3 3.4 0.86 9.3 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3154) Nop14 PF04147.7 KFH47867.1 - 3e-253 842.6 34.4 3.7e-253 842.2 23.8 1.0 1 0 0 1 1 1 1 Nop14-like family DUF702 PF05142.7 KFH47868.1 - 0.013 15.6 0.1 0.017 15.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) HAMP PF00672.20 KFH47869.1 - 6.7e-47 157.5 18.6 1.4e-10 41.1 0.3 7.0 6 0 0 6 6 6 6 HAMP domain HATPase_c PF02518.21 KFH47869.1 - 2.2e-30 104.6 0.3 9.6e-30 102.5 0.2 2.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KFH47869.1 - 4.5e-28 97.4 0.6 2.1e-25 88.8 0.1 3.5 2 1 1 3 3 3 1 Response regulator receiver domain HisKA PF00512.20 KFH47869.1 - 1.2e-18 66.8 7.3 6.7e-18 64.4 0.4 4.8 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain Pox_A_type_inc PF04508.7 KFH47869.1 - 0.029 14.1 0.2 2.9 7.9 0.2 4.3 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat NAAA-beta PF15508.1 KFH47869.1 - 0.15 12.4 6.2 5.9 7.3 0.1 5.6 4 2 3 7 7 7 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF2365 PF10157.4 KFH47869.1 - 0.17 11.7 17.0 7.5 6.4 0.1 6.8 5 2 1 7 7 7 0 Uncharacterized conserved protein (DUF2365) DUF883 PF05957.8 KFH47869.1 - 2.7 8.4 21.6 1.7 9.1 0.2 6.1 5 2 1 6 6 6 0 Bacterial protein of unknown function (DUF883) MoaC PF01967.16 KFH47870.1 - 1.9e-53 179.7 3.7 3.7e-53 178.8 2.6 1.5 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 KFH47870.1 - 1.6e-34 118.3 0.0 5.5e-34 116.6 0.0 1.9 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 KFH47870.1 - 4.7e-20 72.4 0.1 9.7e-20 71.3 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.1 KFH47870.1 - 0.00015 21.9 0.0 0.00037 20.6 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 KFH47870.1 - 0.00016 21.7 0.0 0.00039 20.4 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF4187 PF13821.1 KFH47871.1 - 3.1e-18 65.1 1.7 1.3e-17 63.0 1.2 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 KFH47871.1 - 4.1e-10 39.2 6.5 1e-09 38.0 4.5 1.7 1 1 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KFH47871.1 - 0.041 13.7 4.4 0.041 13.7 1.2 2.5 2 0 0 2 2 2 0 DExH-box splicing factor binding site BTV_NS2 PF04514.7 KFH47871.1 - 3.6 6.3 17.3 0.14 10.9 7.1 1.9 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 Hex_IIIa PF02455.11 KFH47871.1 - 8.2 4.9 12.2 0.19 10.4 3.0 1.8 1 1 1 2 2 2 0 Hexon-associated protein (IIIa) Peptidase_M3 PF01432.15 KFH47872.1 - 3.7e-119 398.7 0.0 5.6e-119 398.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 KFH47872.1 - 0.025 13.9 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase M50B-like Oxysterol_BP PF01237.13 KFH47873.1 - 2.8e-88 295.7 0.0 3.7e-88 295.3 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein RRM_6 PF14259.1 KFH47874.1 - 8.8e-11 41.6 0.0 4.7e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFH47874.1 - 4e-10 39.1 0.0 4.4e-05 23.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH47874.1 - 0.0006 19.6 0.0 0.013 15.3 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MARVEL PF01284.18 KFH47875.1 - 0.0061 16.3 5.9 0.0061 16.3 4.1 2.0 2 1 1 3 3 3 1 Membrane-associating domain MutS_V PF00488.16 KFH47876.1 - 2e-81 272.8 0.0 3.6e-81 272.0 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KFH47876.1 - 2.5e-40 138.4 5.1 4.4e-40 137.6 3.6 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KFH47876.1 - 1.4e-18 66.9 0.0 6.5e-18 64.8 0.0 2.1 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 KFH47876.1 - 5.8e-09 36.1 0.0 1.7e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 KFH47876.1 - 0.0065 16.6 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_22 PF13401.1 KFH47876.1 - 0.021 14.9 1.5 1.5 8.9 0.0 3.2 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KFH47876.1 - 0.03 13.8 0.0 0.068 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 KFH47876.1 - 0.28 11.4 0.4 0.76 10.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain SNF2_N PF00176.18 KFH47877.1 - 1.8e-62 210.8 0.0 2.8e-62 210.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 KFH47877.1 - 1.3e-24 85.5 10.8 1e-15 57.1 0.2 3.3 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 KFH47877.1 - 3.8e-14 52.2 0.0 1.1e-13 50.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.1 KFH47877.1 - 7e-06 26.1 0.1 2.7e-05 24.3 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) DnaJ PF00226.26 KFH47878.1 - 7.3e-13 48.0 1.1 1.2e-12 47.3 0.2 1.9 2 0 0 2 2 2 1 DnaJ domain RRS1 PF04939.7 KFH47879.1 - 6e-56 188.4 3.5 7e-56 188.2 2.4 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Peptidase_M22 PF00814.20 KFH47880.1 - 4.7e-47 160.7 0.0 2.6e-45 155.0 0.0 2.8 1 1 0 1 1 1 1 Glycoprotease family YycC PF14174.1 KFH47880.1 - 0.039 13.6 0.1 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 YycC-like protein Inositol_P PF00459.20 KFH47882.1 - 2.9e-43 148.1 0.0 5.3e-43 147.2 0.0 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family GMC_oxred_N PF00732.14 KFH47883.1 - 3.7e-46 157.6 0.2 6e-46 156.9 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFH47883.1 - 1.6e-25 90.0 1.0 6e-25 88.2 0.2 2.3 2 1 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 KFH47883.1 - 3.6e-07 29.4 0.9 0.015 14.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFH47883.1 - 4.2e-07 29.1 0.1 9.2e-05 21.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 KFH47883.1 - 3.8e-05 23.6 0.1 0.0001 22.2 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFH47883.1 - 0.00019 20.5 0.0 0.00034 19.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KFH47883.1 - 0.00053 19.9 0.3 0.0017 18.2 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KFH47883.1 - 0.00073 18.7 0.1 0.0022 17.1 0.1 1.8 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KFH47883.1 - 0.0062 15.0 0.1 0.011 14.2 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 KFH47883.1 - 0.17 10.7 0.4 0.43 9.4 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein DUF3818 PF12825.2 KFH47884.1 - 3.1e-136 453.5 4.8 4.1e-136 453.1 3.3 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 KFH47884.1 - 1.3e-42 144.6 0.2 3.1e-42 143.4 0.1 1.6 1 0 0 1 1 1 1 PX-associated PX PF00787.19 KFH47884.1 - 2.2e-14 53.2 0.2 4.8e-13 48.8 0.0 3.2 3 1 0 3 3 3 1 PX domain Myc_N PF01056.13 KFH47884.1 - 0.0093 15.1 1.0 0.0093 15.1 0.7 1.7 2 0 0 2 2 2 1 Myc amino-terminal region AAA PF00004.24 KFH47885.1 - 7.3e-57 191.2 0.0 1.3e-43 148.3 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 KFH47885.1 - 1.1e-26 92.6 0.1 2.5e-26 91.5 0.1 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 KFH47885.1 - 2.6e-10 40.5 6.9 4.6e-05 23.4 0.0 4.7 4 1 1 5 5 4 2 AAA ATPase domain AAA_17 PF13207.1 KFH47885.1 - 3.2e-07 31.2 0.0 0.034 14.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KFH47885.1 - 5e-07 29.9 1.1 0.0053 16.8 0.0 3.7 3 1 0 3 3 2 2 AAA domain NACHT PF05729.7 KFH47885.1 - 1.2e-06 28.2 0.2 0.0017 18.0 0.0 3.3 3 0 0 3 3 3 1 NACHT domain AAA_2 PF07724.9 KFH47885.1 - 1.5e-06 28.2 0.0 0.043 13.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 KFH47885.1 - 1.9e-06 28.1 0.1 0.0018 18.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain Sigma54_activ_2 PF14532.1 KFH47885.1 - 6.5e-06 26.2 0.0 0.0017 18.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 KFH47885.1 - 7.6e-06 25.8 0.0 0.057 13.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KFH47885.1 - 1e-05 25.3 0.1 0.14 11.9 0.0 3.6 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 KFH47885.1 - 6.6e-05 22.1 0.0 0.12 11.4 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_19 PF13245.1 KFH47885.1 - 6.8e-05 22.5 0.3 0.73 9.6 0.0 3.7 3 0 0 3 3 3 2 Part of AAA domain RuvB_N PF05496.7 KFH47885.1 - 7.2e-05 21.9 0.0 0.012 14.6 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KFH47885.1 - 0.00013 21.8 0.1 0.32 10.8 0.0 2.8 2 1 0 2 2 2 2 AAA domain TIP49 PF06068.8 KFH47885.1 - 0.0004 19.2 0.0 0.65 8.6 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus UPF0079 PF02367.12 KFH47885.1 - 0.00063 19.3 0.1 0.015 14.9 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 KFH47885.1 - 0.0011 18.3 0.2 1.4 8.2 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.1 KFH47885.1 - 0.0011 18.3 3.1 1.8 7.8 0.1 4.1 2 2 2 4 4 4 1 AAA domain RNA_helicase PF00910.17 KFH47885.1 - 0.0014 18.8 0.0 2.7 8.1 0.0 2.5 2 0 0 2 2 2 2 RNA helicase SKI PF01202.17 KFH47885.1 - 0.0018 18.1 0.1 0.84 9.4 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Mg_chelatase PF01078.16 KFH47885.1 - 0.0019 17.3 0.1 0.68 9.0 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KFH47885.1 - 0.0033 16.9 0.0 0.19 11.1 0.0 2.6 3 0 0 3 3 2 1 Sigma-54 interaction domain Arch_ATPase PF01637.13 KFH47885.1 - 0.0045 16.7 0.6 0.32 10.6 0.0 3.0 2 2 1 3 3 3 1 Archaeal ATPase KAP_NTPase PF07693.9 KFH47885.1 - 0.0047 15.9 0.2 2 7.3 0.0 2.5 1 1 1 2 2 2 1 KAP family P-loop domain ABC_tran PF00005.22 KFH47885.1 - 0.006 16.8 0.0 2.2 8.5 0.0 2.8 3 0 0 3 3 2 1 ABC transporter AAA_28 PF13521.1 KFH47885.1 - 0.01 15.7 0.0 4.9 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 KFH47885.1 - 0.012 14.7 0.0 2.8 6.9 0.0 2.4 2 0 0 2 2 2 0 KaiC NB-ARC PF00931.17 KFH47885.1 - 0.015 14.1 0.2 3.9 6.2 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain DUF815 PF05673.8 KFH47885.1 - 0.022 13.6 0.0 0.35 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 KFH47885.1 - 0.025 14.1 0.7 6.7 6.2 0.2 2.4 2 0 0 2 2 2 0 AAA domain Cytidylate_kin2 PF13189.1 KFH47885.1 - 0.028 14.3 0.2 5.2 6.9 0.0 2.8 2 1 0 2 2 2 0 Cytidylate kinase-like family APS_kinase PF01583.15 KFH47885.1 - 0.03 13.9 0.2 0.14 11.8 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase MobB PF03205.9 KFH47885.1 - 0.036 13.7 0.0 0.88 9.2 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 KFH47885.1 - 0.045 12.6 0.0 0.34 9.7 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein NTPase_1 PF03266.10 KFH47885.1 - 0.075 12.7 0.1 1.9 8.1 0.0 2.5 3 0 0 3 3 2 0 NTPase PhoH PF02562.11 KFH47885.1 - 0.082 12.1 0.1 12 5.0 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein KTI12 PF08433.5 KFH47885.1 - 0.082 12.0 0.1 0.57 9.3 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_3 PF07726.6 KFH47885.1 - 0.13 11.8 0.0 6.9 6.2 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 KFH47885.1 - 0.19 10.6 0.0 7.2 5.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.12 KFH47885.1 - 0.35 9.7 0.0 24 3.6 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 zf-C2H2 PF00096.21 KFH47886.1 - 4.2e-13 48.8 6.1 8.6e-06 25.7 0.8 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type Fungal_trans PF04082.13 KFH47886.1 - 1.1e-12 47.4 0.4 2.6e-12 46.1 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 KFH47886.1 - 1.3e-09 37.7 6.4 5.6e-05 23.1 0.2 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFH47886.1 - 7e-07 29.2 4.5 0.0037 17.4 0.4 3.7 3 0 0 3 3 3 2 Zinc-finger double domain Zn_clus PF00172.13 KFH47886.1 - 3.9e-06 26.6 10.1 1e-05 25.3 7.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-met PF12874.2 KFH47886.1 - 0.11 12.6 0.1 0.11 12.6 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFH47886.1 - 4.6 7.4 9.9 0.25 11.5 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Peptidase_M16_C PF05193.16 KFH47887.1 - 3e-34 118.2 0.0 2.6e-21 76.1 0.0 3.8 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KFH47887.1 - 2.1e-31 108.7 0.0 6.5e-31 107.1 0.0 1.9 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) WD40 PF00400.27 KFH47888.1 - 9.2e-05 22.1 0.0 0.017 14.9 0.0 3.3 4 0 0 4 4 4 1 WD domain, G-beta repeat Macoilin PF09726.4 KFH47888.1 - 6.2 4.9 5.9 9.3 4.3 4.1 1.2 1 0 0 1 1 1 0 Transmembrane protein CTP_transf_2 PF01467.21 KFH47889.1 - 2.7e-19 69.7 0.0 3.5e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase AvrRpt-cleavage PF05627.6 KFH47890.1 - 0.022 13.7 0.7 0.056 12.4 0.5 1.6 1 0 0 1 1 1 0 Cleavage site for pathogenic type III effector avirulence factor Avr zf-GRF PF06839.7 KFH47891.1 - 8.9e-06 25.5 6.8 1.8e-05 24.5 4.7 1.5 1 0 0 1 1 1 1 GRF zinc finger bZIP_1 PF00170.16 KFH47891.1 - 0.048 13.6 0.1 0.092 12.7 0.1 1.4 1 0 0 1 1 1 0 bZIP transcription factor AMP-binding PF00501.23 KFH47892.1 - 0 1672.6 0.0 2.2e-85 286.5 0.0 6.3 6 0 0 6 6 6 6 AMP-binding enzyme Condensation PF00668.15 KFH47892.1 - 0 1300.8 0.0 6.8e-49 166.3 0.0 10.0 9 1 0 9 9 9 9 Condensation domain PP-binding PF00550.20 KFH47892.1 - 1.2e-71 236.9 0.0 7.8e-13 48.4 0.0 6.8 6 0 0 6 6 6 6 Phosphopantetheine attachment site p450 PF00067.17 KFH47892.1 - 4.2e-47 160.7 0.0 9.3e-47 159.5 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 AMP-binding_C PF13193.1 KFH47892.1 - 4.1e-27 94.9 1.6 6.2e-07 30.2 0.0 7.3 6 0 0 6 6 6 5 AMP-binding enzyme C-terminal domain AATase PF07247.7 KFH47892.1 - 0.037 12.5 0.0 6.2 5.2 0.1 3.2 4 0 0 4 4 4 0 Alcohol acetyltransferase Transferase PF02458.10 KFH47892.1 - 0.076 11.4 0.0 0.67 8.3 0.0 2.3 3 0 0 3 3 3 0 Transferase family GH3 PF03321.8 KFH47892.1 - 5.1 5.5 0.0 59 1.9 0.0 2.6 3 0 0 3 3 3 0 GH3 auxin-responsive promoter DAP3 PF10236.4 KFH47893.1 - 2.8e-85 285.9 0.0 3.6e-85 285.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 Orthopox_A36R PF05950.6 KFH47893.1 - 0.16 11.8 0.1 0.39 10.6 0.1 1.5 2 0 0 2 2 2 0 Orthopoxvirus A36R protein zf-CHCC PF10276.4 KFH47894.1 - 2.7e-15 55.9 0.8 3.9e-15 55.3 0.5 1.3 1 0 0 1 1 1 1 Zinc-finger domain ProQ PF04352.8 KFH47894.1 - 0.0096 15.5 0.1 0.014 14.9 0.1 1.2 1 0 0 1 1 1 1 ProQ/FINO family COX5B PF01215.14 KFH47894.1 - 0.025 14.2 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb PDEase_I PF00233.14 KFH47895.1 - 2.2e-42 145.4 0.6 3.2e-39 135.1 0.0 2.3 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase FYVE PF01363.16 KFH47896.1 - 2.8e-20 71.9 1.1 2.8e-20 71.9 0.8 3.1 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 KFH47896.1 - 1.2e-07 31.3 6.3 1.2e-07 31.3 4.4 3.7 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 KFH47896.1 - 0.008 16.2 15.9 0.012 15.7 3.4 3.4 3 0 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KFH47896.1 - 0.008 16.1 6.2 0.008 16.1 4.3 3.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.11 KFH47896.1 - 0.31 10.9 10.6 0.062 13.1 0.9 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger zf-piccolo PF05715.8 KFH47896.1 - 0.67 9.9 5.8 2.3 8.2 1.8 2.7 2 0 0 2 2 2 0 Piccolo Zn-finger Rad50_zn_hook PF04423.9 KFH47896.1 - 1.4 8.4 7.7 0.14 11.6 0.4 2.5 3 0 0 3 3 3 0 Rad50 zinc hook motif ABC_tran PF00005.22 KFH47898.1 - 6.7e-35 120.3 0.0 2.7e-17 63.3 0.0 2.6 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KFH47898.1 - 2.2e-13 50.8 4.1 0.023 14.6 0.0 4.3 2 2 2 4 4 4 4 AAA domain RLI PF04068.10 KFH47898.1 - 2.9e-12 45.9 5.4 2.9e-12 45.9 3.8 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.14 KFH47898.1 - 9.4e-12 44.6 1.1 0.00025 20.3 0.0 3.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KFH47898.1 - 6.5e-08 32.0 1.5 0.84 8.6 0.0 4.4 3 2 0 5 5 5 2 AAA ATPase domain AAA_17 PF13207.1 KFH47898.1 - 6.4e-06 26.9 0.1 0.11 13.3 0.0 2.8 2 2 0 2 2 2 2 AAA domain Fer4 PF00037.22 KFH47898.1 - 8.8e-06 25.1 2.7 8.8e-06 25.1 1.9 2.6 3 0 0 3 3 2 1 4Fe-4S binding domain AAA PF00004.24 KFH47898.1 - 2.8e-05 24.3 0.0 0.035 14.3 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 KFH47898.1 - 3.9e-05 23.1 0.3 0.1 12.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.1 KFH47898.1 - 8.1e-05 22.9 0.4 0.55 10.5 0.0 3.1 3 1 0 3 3 2 2 AAA domain AAA_22 PF13401.1 KFH47898.1 - 8.1e-05 22.7 0.0 0.017 15.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.1 KFH47898.1 - 0.00046 19.9 10.9 0.00089 19.0 7.6 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain DUF258 PF03193.11 KFH47898.1 - 0.00052 19.2 2.6 0.73 9.0 0.0 3.1 3 0 0 3 3 2 2 Protein of unknown function, DUF258 MobB PF03205.9 KFH47898.1 - 0.00075 19.2 0.9 0.13 11.9 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 KFH47898.1 - 0.001 19.4 0.0 0.063 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KFH47898.1 - 0.0016 18.3 0.1 0.27 11.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KFH47898.1 - 0.0016 18.5 0.1 0.77 9.9 0.0 2.6 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.7 KFH47898.1 - 0.0019 17.8 0.6 0.52 9.9 0.0 2.6 2 0 0 2 2 2 1 NACHT domain VirE PF05272.6 KFH47898.1 - 0.0023 17.4 0.0 1.3 8.4 0.0 2.6 2 0 0 2 2 2 1 Virulence-associated protein E Rad17 PF03215.10 KFH47898.1 - 0.0026 16.5 0.0 0.079 11.6 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein SRP54 PF00448.17 KFH47898.1 - 0.0027 17.1 3.0 0.061 12.7 0.1 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_7 PF12838.2 KFH47898.1 - 0.0028 18.0 7.7 0.0064 16.8 0.3 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain NB-ARC PF00931.17 KFH47898.1 - 0.0035 16.2 0.0 0.25 10.1 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain UPF0079 PF02367.12 KFH47898.1 - 0.0036 16.9 0.4 0.046 13.3 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 KFH47898.1 - 0.0048 16.9 0.1 1.2 9.0 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain Fer4_6 PF12837.2 KFH47898.1 - 0.0065 16.2 2.6 0.0065 16.2 1.8 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_13 PF13166.1 KFH47898.1 - 0.0087 14.5 0.0 0.0087 14.5 0.0 2.6 4 0 0 4 4 3 1 AAA domain AAA_25 PF13481.1 KFH47898.1 - 0.01 15.2 0.0 5.6 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.12 KFH47898.1 - 0.017 14.4 1.1 3.3 7.0 0.0 3.1 3 0 0 3 3 3 0 Thymidylate kinase Miro PF08477.8 KFH47898.1 - 0.018 15.5 0.1 1.4 9.4 0.0 2.8 3 0 0 3 3 2 0 Miro-like protein SbcCD_C PF13558.1 KFH47898.1 - 0.02 14.7 0.0 9.5 6.2 0.0 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Fer4_10 PF13237.1 KFH47898.1 - 0.023 14.5 1.6 0.023 14.5 1.1 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_5 PF07728.9 KFH47898.1 - 0.032 13.9 0.8 1 9.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 KFH47898.1 - 0.051 13.5 0.1 4.2 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_16 PF13484.1 KFH47898.1 - 0.072 13.8 0.2 0.072 13.8 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain PduV-EutP PF10662.4 KFH47898.1 - 0.073 12.5 3.1 0.41 10.1 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 KFH47898.1 - 0.13 11.7 1.5 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 KFH47898.1 - 0.15 11.2 0.5 0.48 9.5 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Fer4_8 PF13183.1 KFH47898.1 - 0.2 11.7 8.6 0.41 10.7 1.3 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_30 PF13604.1 KFH47898.1 - 0.21 11.1 0.1 5 6.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 KFH47898.1 - 0.37 10.4 2.3 11 5.6 0.1 2.6 2 0 0 2 2 2 0 NTPase Fer4_9 PF13187.1 KFH47898.1 - 1.4 9.2 13.9 0.052 13.8 1.5 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 KFH47898.1 - 1.5 8.8 12.7 0.2 11.6 1.8 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain ABC_membrane PF00664.18 KFH47899.1 - 1.2e-72 244.6 31.3 4.3e-41 141.1 6.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFH47899.1 - 4.9e-64 214.7 0.0 4.9e-31 107.8 0.0 3.0 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KFH47899.1 - 3.2e-12 47.0 0.1 0.039 13.9 0.1 4.2 3 1 1 4 4 4 3 AAA domain SMC_N PF02463.14 KFH47899.1 - 4.3e-12 45.7 4.9 4e-05 22.9 0.5 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 KFH47899.1 - 2.6e-09 36.2 0.0 0.0093 14.5 0.0 3.5 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 KFH47899.1 - 1.5e-08 34.8 1.6 0.0012 18.8 0.1 3.2 3 0 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 KFH47899.1 - 3e-08 33.0 0.0 0.0033 16.6 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_30 PF13604.1 KFH47899.1 - 4.4e-08 32.9 0.8 0.0068 16.0 0.0 4.0 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KFH47899.1 - 1.5e-07 30.8 0.1 0.0004 19.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 KFH47899.1 - 2.8e-07 30.7 1.4 0.021 14.9 0.0 4.0 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KFH47899.1 - 4.3e-07 30.7 0.3 0.0092 16.7 0.1 2.9 2 1 0 3 3 2 2 AAA domain AAA_23 PF13476.1 KFH47899.1 - 2.3e-06 28.1 0.1 0.0017 18.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KFH47899.1 - 8.2e-06 25.3 1.1 0.11 11.8 0.0 3.3 4 0 0 4 4 3 2 AAA domain AAA_15 PF13175.1 KFH47899.1 - 8.9e-06 24.9 0.1 0.079 11.9 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 KFH47899.1 - 6.5e-05 22.6 0.0 0.35 10.6 0.0 3.3 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KFH47899.1 - 0.00028 20.5 0.0 0.022 14.5 0.0 3.0 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 KFH47899.1 - 0.0003 20.6 0.0 0.36 10.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 KFH47899.1 - 0.00045 20.5 0.1 0.39 11.0 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KFH47899.1 - 0.00054 19.8 0.0 0.063 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 KFH47899.1 - 0.0011 18.4 0.0 0.41 10.1 0.0 2.8 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.1 KFH47899.1 - 0.0015 18.4 2.1 0.69 9.8 0.2 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA PF00004.24 KFH47899.1 - 0.0015 18.6 3.3 7.2 6.8 0.0 4.6 4 1 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) ABC_membrane_3 PF13748.1 KFH47899.1 - 0.0034 16.4 0.2 0.0084 15.1 0.1 1.6 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_10 PF12846.2 KFH47899.1 - 0.0036 16.7 0.2 0.056 12.8 0.0 2.7 3 0 0 3 3 3 1 AAA-like domain MobB PF03205.9 KFH47899.1 - 0.0043 16.7 0.1 0.43 10.2 0.1 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 KFH47899.1 - 0.0056 16.6 0.1 2.5 8.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain PRK PF00485.13 KFH47899.1 - 0.0084 15.6 0.0 3.7 7.0 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Arch_ATPase PF01637.13 KFH47899.1 - 0.023 14.3 0.3 2.1 7.9 0.0 3.2 3 0 0 3 3 3 0 Archaeal ATPase AAA_11 PF13086.1 KFH47899.1 - 0.023 14.2 0.1 0.17 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KFH47899.1 - 0.025 14.5 0.1 2.1 8.3 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.7 KFH47899.1 - 0.026 13.5 0.0 5.7 5.9 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin SRP54 PF00448.17 KFH47899.1 - 0.038 13.4 0.0 4.4 6.6 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF87 PF01935.12 KFH47899.1 - 0.043 13.6 0.0 0.43 10.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 Miro PF08477.8 KFH47899.1 - 0.065 13.7 0.1 13 6.2 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein NB-ARC PF00931.17 KFH47899.1 - 0.072 11.9 0.0 3.9 6.2 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.17 KFH47899.1 - 0.14 12.3 0.0 16 5.7 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.10 KFH47899.1 - 0.17 10.5 0.1 3.6 6.1 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein ADK PF00406.17 KFH47900.1 - 4.4e-44 150.0 0.0 5.7e-44 149.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 KFH47900.1 - 5.6e-08 33.1 0.0 9.4e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFH47900.1 - 2.8e-07 30.5 0.0 7.8e-07 29.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFH47900.1 - 2.6e-06 28.2 0.0 4.2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KFH47900.1 - 0.00039 19.8 0.2 0.17 11.2 0.0 2.3 2 0 0 2 2 2 2 Thymidylate kinase PT PF04886.7 KFH47900.1 - 0.0042 16.3 11.7 0.011 15.0 8.1 1.7 1 0 0 1 1 1 1 PT repeat Zeta_toxin PF06414.7 KFH47900.1 - 0.12 11.4 0.1 0.24 10.4 0.1 1.7 1 1 0 1 1 1 0 Zeta toxin Prenyltrans PF00432.16 KFH47901.1 - 1.4e-59 197.2 10.4 2.8e-12 45.9 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KFH47901.1 - 6.5e-32 110.2 0.0 1.6e-14 54.2 0.0 4.0 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KFH47901.1 - 3.6e-11 43.0 0.0 6.8e-05 22.8 0.0 2.7 2 1 1 3 3 3 2 Prenyltransferase-like Herpes_US9 PF06072.6 KFH47902.1 - 0.42 10.4 2.4 0.85 9.5 1.7 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 AAA_11 PF13086.1 KFH47903.1 - 5.2e-61 206.2 0.1 1.2e-60 204.9 0.1 1.6 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 KFH47903.1 - 1.6e-53 181.0 0.0 3.3e-53 180.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFH47903.1 - 2.6e-13 49.5 1.0 2.4e-12 46.4 0.0 2.9 3 0 0 3 3 3 1 Part of AAA domain AAA_30 PF13604.1 KFH47903.1 - 2.3e-11 43.6 0.0 1.4e-09 37.8 0.0 2.7 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KFH47903.1 - 6.2e-07 29.4 0.0 1.5e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KFH47903.1 - 8.7e-07 28.6 0.0 0.33 10.4 0.0 3.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 KFH47903.1 - 4.9e-06 25.7 0.2 2.6e-05 23.3 0.1 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 KFH47903.1 - 7.6e-06 25.5 0.1 0.00018 21.0 0.1 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase UvrD-helicase PF00580.16 KFH47903.1 - 0.0001 21.7 0.1 0.0004 19.7 0.1 1.9 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.9 KFH47903.1 - 0.00035 20.2 0.0 0.02 14.5 0.0 2.5 1 1 0 1 1 1 1 Helicase AAA_22 PF13401.1 KFH47903.1 - 0.0004 20.5 0.0 0.038 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zot PF05707.7 KFH47903.1 - 0.00057 19.4 0.1 0.0056 16.1 0.0 2.4 2 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_25 PF13481.1 KFH47903.1 - 0.00064 19.1 0.1 0.0043 16.4 0.0 2.4 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KFH47903.1 - 0.0017 17.7 0.0 0.0055 16.1 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein TrwB_AAD_bind PF10412.4 KFH47903.1 - 0.0018 17.0 0.0 0.0031 16.2 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain 4HB_MCP_1 PF12729.2 KFH47903.1 - 0.0046 16.3 1.2 0.0053 16.1 0.1 1.5 2 0 0 2 2 1 1 Four helix bundle sensory module for signal transduction T2SE PF00437.15 KFH47903.1 - 0.0047 15.8 0.0 0.009 14.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 KFH47903.1 - 0.0071 16.3 0.0 0.02 14.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain PhoH PF02562.11 KFH47903.1 - 0.012 14.8 0.0 0.066 12.4 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein Flavi_DEAD PF07652.9 KFH47903.1 - 0.013 15.3 0.1 0.046 13.4 0.0 1.9 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_5 PF07728.9 KFH47903.1 - 0.013 15.1 0.0 0.051 13.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 KFH47903.1 - 0.014 14.8 0.0 0.054 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA-like domain AAA PF00004.24 KFH47903.1 - 0.021 15.0 0.3 0.099 12.8 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 KFH47903.1 - 0.04 13.6 0.5 3.9 7.1 0.0 2.5 2 0 0 2 2 2 0 NTPase UvrD_C PF13361.1 KFH47903.1 - 0.047 13.1 0.0 27 4.0 0.0 3.1 2 1 1 3 3 3 0 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.1 KFH47903.1 - 0.052 13.6 0.0 5.4 7.2 0.0 2.7 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain PIF1 PF05970.9 KFH47903.1 - 0.062 12.2 0.0 0.9 8.4 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase KaiC PF06745.8 KFH47903.1 - 0.072 12.2 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.22 KFH47903.1 - 0.089 13.0 0.0 0.25 11.6 0.0 1.9 1 0 0 1 1 1 0 ABC transporter DEAD PF00270.24 KFH47904.1 - 3.8e-41 140.4 0.0 2e-40 138.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFH47904.1 - 1e-25 89.3 0.1 2.1e-25 88.3 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFH47904.1 - 0.06 13.1 1.5 0.16 11.7 0.0 2.4 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit PRAI PF00697.17 KFH47904.1 - 0.32 10.5 0.0 0.32 10.5 0.0 1.7 2 0 0 2 2 2 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase APH PF01636.18 KFH47905.1 - 1.3e-09 38.1 0.2 2.1e-09 37.4 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFH47905.1 - 0.012 15.1 0.0 0.025 14.1 0.0 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase FHA PF00498.21 KFH47907.1 - 4.2e-17 62.0 0.3 9.4e-17 60.8 0.1 1.7 2 0 0 2 2 2 1 FHA domain MutS_V PF00488.16 KFH47908.1 - 1e-83 280.3 0.0 1.9e-83 279.4 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KFH47908.1 - 7.4e-39 133.6 3.4 1.4e-38 132.7 2.3 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KFH47908.1 - 5.2e-29 100.5 0.0 1.3e-28 99.3 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 KFH47908.1 - 8e-11 42.1 0.4 4e-08 33.4 0.0 2.7 2 0 0 2 2 2 2 MutS domain II MutS_IV PF05190.13 KFH47908.1 - 3.9e-08 33.3 0.1 1.3e-07 31.6 0.1 2.0 1 0 0 1 1 1 1 MutS family domain IV Glyco_hydro_16 PF00722.16 KFH47909.1 - 2.8e-08 33.2 0.1 1.2e-06 27.9 0.0 2.8 2 1 0 2 2 2 2 Glycosyl hydrolases family 16 Cupin_8 PF13621.1 KFH47910.1 - 7.3e-19 68.2 0.1 4.5e-17 62.4 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain F-box-like PF12937.2 KFH47910.1 - 2.9e-10 39.7 0.3 7.3e-10 38.4 0.1 1.8 2 0 0 2 2 2 1 F-box-like JmjC PF02373.17 KFH47910.1 - 1.1e-09 38.5 0.0 2.5e-09 37.3 0.0 1.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box PF00646.28 KFH47910.1 - 7e-07 28.7 0.1 1.5e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain Cupin_4 PF08007.7 KFH47910.1 - 0.034 13.3 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein APH PF01636.18 KFH47911.1 - 0.0014 18.3 0.4 0.0026 17.5 0.2 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KFH47911.1 - 0.0058 15.7 0.0 0.015 14.3 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFH47911.1 - 0.014 14.7 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Trs65 PF12735.2 KFH47912.1 - 1.1e-70 238.4 0.0 1.5e-70 237.9 0.0 1.2 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 SNARE_assoc PF09335.6 KFH47913.1 - 3.6e-15 56.2 5.6 3.6e-15 56.2 3.9 2.5 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF3619 PF12279.3 KFH47913.1 - 0.079 13.0 0.3 0.2 11.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) Nucleos_tra2_N PF01773.15 KFH47913.1 - 0.11 12.8 4.5 1 9.7 0.6 2.6 2 1 0 2 2 2 0 Na+ dependent nucleoside transporter N-terminus PepSY_TM_2 PF13703.1 KFH47913.1 - 8.8 6.5 11.3 0.27 11.4 2.6 2.3 3 0 0 3 3 3 0 PepSY-associated TM helix DUF1348 PF07080.6 KFH47914.1 - 4.2e-48 162.7 6.0 5.1e-48 162.5 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.2 KFH47914.1 - 5e-08 33.2 0.7 6.6e-08 32.8 0.5 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 KFH47914.1 - 8.8e-05 22.6 0.1 0.00014 21.9 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.7 KFH47914.1 - 0.0056 16.2 0.0 0.0087 15.6 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase NDUF_B6 PF09782.4 KFH47914.1 - 1.1 9.1 5.1 2.9 7.7 0.9 2.1 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit OTT_1508_deam PF14441.1 KFH47915.1 - 5.5e-11 42.4 0.0 1.2e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase Adeno_E1B_19K PF01691.11 KFH47915.1 - 0.13 11.5 0.8 0.67 9.2 0.2 2.2 2 0 0 2 2 2 0 Adenovirus E1B 19K protein / small t-antigen 14-3-3 PF00244.15 KFH47916.1 - 2.8e-115 383.3 4.8 3.2e-115 383.1 3.3 1.0 1 0 0 1 1 1 1 14-3-3 protein Ribosomal_L1 PF00687.16 KFH47917.1 - 6.5e-52 176.0 0.6 8e-52 175.7 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family CorA PF01544.13 KFH47919.1 - 9.6e-10 37.9 1.8 6.1e-09 35.3 1.2 2.2 1 1 1 2 2 2 1 CorA-like Mg2+ transporter protein Zot PF05707.7 KFH47919.1 - 0.024 14.1 0.0 0.22 10.9 0.0 2.4 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) MFS_1 PF07690.11 KFH47920.1 - 2.8e-25 88.8 21.5 6.4e-25 87.6 14.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DnaA_N PF11638.3 KFH47920.1 - 0.0054 16.2 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 DnaA N-terminal domain HlyIII PF03006.15 KFH47920.1 - 0.068 12.5 5.1 0.21 10.9 0.4 2.4 2 0 0 2 2 2 0 Haemolysin-III related GTP_EFTU PF00009.22 KFH47921.1 - 5.7e-38 130.2 0.0 9.7e-38 129.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 KFH47921.1 - 4.1e-36 122.9 0.3 8.7e-36 121.8 0.2 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 KFH47921.1 - 4.5e-10 39.4 0.6 1.2e-09 38.0 0.2 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KFH47921.1 - 0.0084 16.0 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ApoO PF09769.4 KFH47922.1 - 9.8e-49 165.0 0.1 2e-48 164.1 0.0 1.6 2 0 0 2 2 2 1 Apolipoprotein O DUF4407 PF14362.1 KFH47922.1 - 0.15 10.9 0.3 0.23 10.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Arf PF00025.16 KFH47923.1 - 2e-74 248.6 0.0 2.2e-74 248.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KFH47923.1 - 1.7e-12 46.9 0.0 2e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KFH47923.1 - 8.4e-12 44.7 0.0 1e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KFH47923.1 - 1.6e-11 43.5 0.7 1.1e-07 30.9 0.0 2.3 1 1 0 2 2 2 2 G-protein alpha subunit Miro PF08477.8 KFH47923.1 - 3e-09 37.3 0.0 4.2e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 KFH47923.1 - 8.2e-09 34.9 0.0 9.7e-09 34.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFH47923.1 - 2.5e-06 27.4 0.0 3.8e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFH47923.1 - 5.6e-06 25.9 0.0 0.00081 18.8 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KFH47923.1 - 0.0096 15.2 0.6 0.043 13.1 0.4 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF3986 PF13143.1 KFH47923.1 - 0.091 13.2 0.2 0.27 11.7 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3986) Transcrip_reg PF01709.15 KFH47924.1 - 1.1e-50 171.9 0.0 1.2e-50 171.7 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator Cnd2 PF05786.9 KFH47925.1 - 2e-207 691.1 5.4 2.7e-207 690.7 3.8 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 Alginate_lyase2 PF08787.6 KFH47926.1 - 1.9e-40 138.9 0.0 2.9e-40 138.3 0.0 1.3 1 0 0 1 1 1 1 Alginate lyase ELMO_CED12 PF04727.8 KFH47927.1 - 1.7e-48 164.3 0.1 2.7e-48 163.7 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 KFH47927.1 - 4.2e-07 29.8 1.6 1.7e-05 24.6 1.1 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3361) CENP-F_N PF10481.4 KFH47928.1 - 0.025 13.9 0.3 0.033 13.5 0.2 1.1 1 0 0 1 1 1 0 Cenp-F N-terminal domain TAF1D PF15333.1 KFH47928.1 - 0.19 11.4 5.5 0.29 10.8 3.8 1.3 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D SR-25 PF10500.4 KFH47928.1 - 0.24 10.8 9.6 0.34 10.3 6.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PRCH PF03967.8 KFH47928.1 - 0.28 10.7 1.2 0.42 10.1 0.8 1.2 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region YqzE PF14038.1 KFH47928.1 - 3.1 7.5 5.1 6.8 6.5 3.6 1.5 1 0 0 1 1 1 0 YqzE-like protein Topoisom_I_N PF02919.10 KFH47929.1 - 1.9e-89 298.6 6.4 1.9e-89 298.6 4.4 3.4 3 1 1 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 KFH47929.1 - 1.1e-85 286.5 4.3 1.1e-85 286.5 3.0 2.1 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 KFH47929.1 - 2e-27 94.6 0.2 2e-27 94.6 0.1 2.2 2 0 0 2 2 2 1 C-terminal topoisomerase domain Pkinase PF00069.20 KFH47930.1 - 7.2e-36 123.6 0.0 4e-20 72.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFH47930.1 - 3.1e-14 52.6 0.0 1.4e-12 47.2 0.0 2.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFH47930.1 - 8.3e-05 22.4 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KFH47930.1 - 0.019 13.9 0.0 2.2 7.1 0.0 2.2 2 0 0 2 2 2 0 Kinase-like DnaJ PF00226.26 KFH47931.1 - 3.1e-25 87.6 3.7 6.3e-25 86.7 2.5 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KFH47931.1 - 2.8e-20 72.0 0.1 1.4e-16 60.1 0.0 2.7 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KFH47931.1 - 2.8e-14 52.8 17.7 5.3e-14 52.0 12.3 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KFH47931.1 - 0.057 13.1 8.5 0.063 12.9 1.3 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family PhnA_Zn_Ribbon PF08274.7 KFH47931.1 - 0.12 12.1 1.1 64 3.4 0.1 3.5 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zf-RING_3 PF14369.1 KFH47931.1 - 0.36 10.8 2.3 27 4.8 0.1 3.4 3 0 0 3 3 3 0 zinc-finger zinc-ribbons_6 PF07191.7 KFH47931.1 - 0.37 10.5 6.1 2.8 7.7 0.9 2.3 2 0 0 2 2 2 0 zinc-ribbons DUF2614 PF11023.3 KFH47931.1 - 0.61 9.8 6.2 1.4 8.6 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) MARVEL PF01284.18 KFH47932.1 - 0.0047 16.7 6.9 0.0047 16.7 4.7 2.0 1 1 1 2 2 2 1 Membrane-associating domain DUF3329 PF11808.3 KFH47932.1 - 0.077 13.0 0.1 2.8 8.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) DUF3609 PF12259.3 KFH47932.1 - 0.12 10.9 0.1 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) DUF2910 PF11139.3 KFH47932.1 - 0.15 11.2 1.7 0.49 9.4 1.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2910) DUF2721 PF11026.3 KFH47932.1 - 0.78 9.3 4.5 2.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF2700 PF10912.3 KFH47932.1 - 0.86 9.5 7.5 5.3 7.0 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2700) Vpu PF00558.14 KFH47932.1 - 2.8 7.5 6.3 2.5 7.7 0.5 2.7 2 1 1 3 3 3 0 Vpu protein DUF3074 PF11274.3 KFH47933.1 - 7.2e-57 191.9 1.4 5.3e-54 182.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3074) START PF01852.14 KFH47933.1 - 0.013 14.8 0.0 0.039 13.2 0.0 1.7 2 0 0 2 2 2 0 START domain DUF2031 PF09592.5 KFH47933.1 - 1.5 7.9 14.7 2.4 7.2 10.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) tRNA-synt_1b PF00579.20 KFH47934.1 - 3.4e-19 69.0 0.0 6.6e-19 68.1 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) PMM PF03332.8 KFH47935.1 - 7.1e-103 342.9 0.0 8.2e-103 342.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 KFH47935.1 - 0.02 14.4 0.0 0.24 10.9 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase CAP_GLY PF01302.20 KFH47936.1 - 7.4e-18 64.0 1.3 1.6e-17 62.9 0.3 1.9 2 0 0 2 2 2 1 CAP-Gly domain AAA_13 PF13166.1 KFH47936.1 - 0.00034 19.2 1.4 0.00034 19.2 1.0 2.8 2 1 1 3 3 3 1 AAA domain Mod_r PF07200.8 KFH47936.1 - 0.025 14.4 9.1 0.42 10.5 0.6 3.2 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein ATG16 PF08614.6 KFH47936.1 - 0.04 13.7 0.2 0.04 13.7 0.1 4.6 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) ADIP PF11559.3 KFH47936.1 - 0.041 13.7 17.9 0.15 11.9 0.9 3.7 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.7 KFH47936.1 - 0.051 13.8 7.1 3.9 7.8 0.3 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.6 KFH47936.1 - 0.053 12.1 22.2 0.3 9.6 4.2 3.3 2 1 2 4 4 4 0 Spc7 kinetochore protein Zn_ribbon_2 PF12674.2 KFH47936.1 - 0.13 12.6 0.4 5.8 7.3 0.0 2.7 2 0 0 2 2 2 0 Putative zinc ribbon domain Prefoldin_2 PF01920.15 KFH47936.1 - 0.14 11.9 20.1 0.45 10.3 1.7 3.8 2 1 1 3 3 3 0 Prefoldin subunit Phage_GP20 PF06810.6 KFH47936.1 - 0.19 11.1 13.2 0.52 9.7 0.3 3.4 4 0 0 4 4 4 0 Phage minor structural protein GP20 Sec2p PF06428.6 KFH47936.1 - 0.21 11.4 20.3 0.72 9.7 1.2 5.0 3 1 1 5 5 5 0 GDP/GTP exchange factor Sec2p TPR_MLP1_2 PF07926.7 KFH47936.1 - 0.25 11.0 25.0 0.013 15.2 4.5 3.6 4 0 0 4 4 4 0 TPR/MLP1/MLP2-like protein ApoLp-III PF07464.6 KFH47936.1 - 0.4 10.6 9.4 0.13 12.2 0.1 2.7 2 1 0 3 3 2 0 Apolipophorin-III precursor (apoLp-III) zf-CCHC_2 PF13696.1 KFH47936.1 - 0.43 10.1 1.5 3.8 7.0 0.1 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 KFH47936.1 - 0.7 9.5 3.8 4.2 7.1 0.3 2.3 2 0 0 2 2 2 0 Zinc knuckle TMF_DNA_bd PF12329.3 KFH47936.1 - 0.78 9.5 38.7 0.04 13.7 3.5 5.6 3 1 3 6 6 6 0 TATA element modulatory factor 1 DNA binding Baculo_PEP_C PF04513.7 KFH47936.1 - 1.2 9.0 6.5 2.6 7.8 0.4 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus PEARLI-4 PF05278.7 KFH47936.1 - 1.5 8.1 13.0 2.5 7.3 4.2 2.5 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF241 PF03087.9 KFH47936.1 - 1.5 8.2 12.1 0.55 9.6 1.0 3.6 4 0 0 4 4 4 0 Arabidopsis protein of unknown function BLOC1_2 PF10046.4 KFH47936.1 - 3.2 7.9 19.0 0.81 9.8 0.3 3.7 4 1 1 5 5 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 EzrA PF06160.7 KFH47936.1 - 3.5 5.7 17.5 88 1.0 12.1 2.8 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA DUF745 PF05335.8 KFH47936.1 - 4.2 6.8 12.6 1.7 8.1 1.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF745) DUF4407 PF14362.1 KFH47936.1 - 4.7 6.0 23.0 21 3.9 3.2 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) TBPIP PF07106.8 KFH47936.1 - 6.4 6.2 18.9 0.9 9.0 0.4 3.4 4 0 0 4 4 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CENP-F_leu_zip PF10473.4 KFH47936.1 - 8.8 6.1 34.6 9.1 6.1 8.9 3.6 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.7 KFH47936.1 - 9.6 5.9 9.7 4.1 7.1 0.6 3.4 3 0 0 3 3 3 0 Laminin Domain II DEAD PF00270.24 KFH47937.1 - 1.7e-17 63.3 0.0 4e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase HHH_5 PF14520.1 KFH47937.1 - 6.2e-07 29.4 0.5 0.0004 20.5 0.0 3.8 4 0 0 4 4 4 1 Helix-hairpin-helix domain Helicase_C PF00271.26 KFH47937.1 - 2.1e-06 27.4 0.0 9.3e-06 25.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFH47937.1 - 0.065 13.0 0.0 0.47 10.2 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Glyco_hydro_16 PF00722.16 KFH47938.1 - 4.9e-40 136.7 0.7 8e-40 136.1 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Mpp10 PF04006.7 KFH47939.1 - 0.044 12.1 0.0 0.063 11.6 0.0 1.1 1 0 0 1 1 1 0 Mpp10 protein IATP PF04568.7 KFH47940.1 - 2.9e-21 75.3 0.8 3.2e-21 75.2 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Atg14 PF10186.4 KFH47940.1 - 0.0075 15.2 1.8 0.0083 15.1 1.3 1.0 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 KFH47940.1 - 0.021 14.4 0.4 0.021 14.3 0.3 1.1 1 0 0 1 1 1 0 IncA protein DUF489 PF04356.7 KFH47940.1 - 0.09 12.3 0.8 0.12 11.9 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF489) NinG PF05766.7 KFH47940.1 - 0.092 12.4 2.0 0.11 12.2 1.4 1.1 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein NPV_P10 PF05531.7 KFH47940.1 - 0.18 12.1 0.7 0.27 11.5 0.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Nop25 PF09805.4 KFH47940.1 - 1.8 8.5 9.7 2.4 8.2 6.7 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) FYVE PF01363.16 KFH47941.1 - 2.2e-16 59.4 8.2 4.8e-16 58.4 5.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.16 KFH47941.1 - 0.12 12.2 4.4 0.18 11.7 1.2 2.3 2 0 0 2 2 2 0 IBR domain zf-AN1 PF01428.11 KFH47941.1 - 0.98 9.3 14.3 0.12 12.2 6.0 2.2 2 0 0 2 2 2 0 AN1-like Zinc finger UQ_con PF00179.21 KFH47943.1 - 6e-23 80.8 0.0 6.9e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFH47943.1 - 1.8e-06 27.7 0.0 2.6e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KFH47943.1 - 0.012 15.3 0.1 0.016 14.8 0.0 1.1 1 0 0 1 1 1 0 UEV domain RWD PF05773.17 KFH47943.1 - 0.037 13.9 0.1 0.06 13.2 0.1 1.4 1 1 0 1 1 1 0 RWD domain PCI PF01399.22 KFH47944.1 - 4.5e-15 55.8 0.3 5.2e-14 52.4 0.0 2.4 2 0 0 2 2 2 1 PCI domain FliL PF03748.9 KFH47944.1 - 0.022 14.7 0.1 0.097 12.6 0.1 2.0 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL TPR_12 PF13424.1 KFH47944.1 - 0.034 14.0 0.0 0.13 12.1 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat WD40 PF00400.27 KFH47945.1 - 3 7.8 5.3 82 3.3 0.0 4.5 5 0 0 5 5 5 0 WD domain, G-beta repeat tRNA-synt_1c PF00749.16 KFH47946.1 - 0.05 12.2 0.1 0.053 12.1 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain IclR PF01614.13 KFH47947.1 - 0.03 14.0 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial transcriptional regulator DUF2428 PF10350.4 KFH47948.1 - 3.5e-64 216.3 0.0 8.9e-64 214.9 0.0 1.8 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 KFH47948.1 - 1.5e-10 40.2 11.4 0.13 12.3 0.0 7.6 7 0 0 7 7 7 4 HEAT repeat HEAT_2 PF13646.1 KFH47948.1 - 1.1e-08 35.2 6.7 0.27 11.5 0.0 6.7 5 1 1 6 6 6 3 HEAT repeats HEAT_EZ PF13513.1 KFH47948.1 - 0.019 15.4 5.7 1.9 9.0 0.0 5.6 5 0 0 5 5 5 0 HEAT-like repeat SBF2 PF12335.3 KFH47948.1 - 0.13 11.5 0.1 0.3 10.3 0.0 1.5 1 0 0 1 1 1 0 Myotubularin protein HEAT_2 PF13646.1 KFH47949.1 - 2.9e-14 53.0 4.8 0.00073 19.7 0.0 6.6 5 1 1 6 6 6 3 HEAT repeats HEAT PF02985.17 KFH47949.1 - 9.8e-07 28.3 15.4 0.18 11.9 0.0 10.1 12 0 0 12 12 12 3 HEAT repeat Vac14_Fab1_bd PF12755.2 KFH47949.1 - 6.4e-06 26.4 0.0 0.033 14.5 0.0 4.3 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HrpB7 PF09486.5 KFH47950.1 - 0.041 13.8 1.2 0.049 13.5 0.8 1.1 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Viral_P18 PF04521.8 KFH47950.1 - 0.072 12.5 0.3 0.085 12.2 0.2 1.1 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein Adeno_PIX PF03955.9 KFH47950.1 - 0.1 13.1 1.0 0.11 13.0 0.7 1.1 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) Hanta_nucleocap PF00846.13 KFH47950.1 - 0.12 11.0 1.1 0.14 10.8 0.8 1.0 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein APH PF01636.18 KFH47951.1 - 1e-11 45.0 1.5 1.9e-11 44.1 1.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-AN1 PF01428.11 KFH47951.1 - 0.00015 21.5 3.0 0.00031 20.5 2.1 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger Clavanin PF05452.6 KFH47951.1 - 0.2 11.6 1.6 0.44 10.5 0.2 2.2 3 0 0 3 3 3 0 Clavanin Nsp1_C PF05064.8 KFH47953.1 - 4.7e-39 132.6 4.2 7e-39 132.0 2.1 1.9 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 KFH47953.1 - 1.5e-21 76.7 228.6 6.9e-05 23.0 32.7 6.8 1 1 3 4 4 3 3 Nucleoporin FG repeat region DUF948 PF06103.6 KFH47953.1 - 0.032 14.0 0.3 0.13 12.1 0.1 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) AAA_13 PF13166.1 KFH47953.1 - 0.18 10.1 7.2 0.51 8.7 1.0 2.1 1 1 1 2 2 2 0 AAA domain TMF_DNA_bd PF12329.3 KFH47953.1 - 0.28 11.0 6.7 2.2 8.1 0.0 3.5 2 2 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Laminin_II PF06009.7 KFH47953.1 - 0.41 10.3 5.7 3.8 7.2 0.2 2.5 1 1 0 2 2 2 0 Laminin Domain II NPV_P10 PF05531.7 KFH47953.1 - 0.44 10.8 1.3 1.5 9.0 0.1 2.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein APG6 PF04111.7 KFH47953.1 - 0.44 9.5 4.8 0.69 8.8 3.1 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 V-SNARE PF05008.10 KFH47953.1 - 0.69 10.1 9.2 0.45 10.7 0.7 3.2 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF4201 PF13870.1 KFH47953.1 - 0.75 9.2 4.3 2.7 7.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF4200 PF13863.1 KFH47953.1 - 2.4 8.1 7.7 21 5.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) GAS PF13851.1 KFH47953.1 - 3.8 6.6 8.7 0.88 8.7 0.2 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Ribul_P_3_epim PF00834.14 KFH47954.1 - 2.9e-64 215.8 0.0 1.3e-63 213.7 0.0 1.8 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.19 KFH47954.1 - 0.039 13.3 0.0 0.084 12.2 0.0 1.6 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family ThiG PF05690.9 KFH47954.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Corona_nucleoca PF00937.13 KFH47955.1 - 0.18 10.6 7.4 0.23 10.3 5.1 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Abhydrolase_6 PF12697.2 KFH47956.1 - 8.2e-10 38.9 1.2 7.7e-09 35.7 0.9 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFH47956.1 - 4.8e-08 32.8 0.0 1.2e-07 31.5 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFH47956.1 - 3.6e-06 26.8 0.0 4.8e-05 23.1 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S28 PF05577.7 KFH47956.1 - 7e-05 21.5 0.0 0.00012 20.8 0.0 1.4 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S15 PF02129.13 KFH47956.1 - 0.00096 18.6 0.0 0.004 16.6 0.0 1.8 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 KFH47956.1 - 0.0017 17.5 0.0 0.0042 16.3 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 KFH47956.1 - 0.048 13.5 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase SLD3 PF08639.5 KFH47957.1 - 9.5e-105 351.0 9.7 9.5e-105 351.0 6.7 1.7 2 0 0 2 2 2 1 DNA replication regulator SLD3 Mito_fiss_reg PF05308.6 KFH47958.1 - 3.9 6.7 17.6 0.31 10.3 6.9 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator ArfGap PF01412.13 KFH47959.1 - 2.5e-34 117.5 0.0 8.8e-34 115.7 0.0 2.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.24 KFH47959.1 - 2.3e-13 50.2 0.1 5.6e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 PH domain EAP30 PF04157.11 KFH47959.1 - 0.11 11.5 1.6 0.73 8.9 0.3 2.3 2 0 0 2 2 2 0 EAP30/Vps36 family Phasin_2 PF09361.5 KFH47959.1 - 0.3 11.1 5.6 0.35 10.9 0.2 2.5 2 0 0 2 2 2 0 Phasin protein DUF202 PF02656.10 KFH47960.1 - 1.5e-23 82.7 3.5 1.5e-23 82.7 2.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Proteasome PF00227.21 KFH47961.1 - 9.7e-47 158.7 0.0 1.2e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF554 PF04474.7 KFH47961.1 - 0.016 14.4 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF554) PRA1 PF03208.14 KFH47962.1 - 7.3e-37 126.0 0.7 1.1e-36 125.4 0.5 1.2 1 0 0 1 1 1 1 PRA1 family protein Trypan_PARP PF05887.6 KFH47962.1 - 2 8.2 15.2 0.8 9.5 6.3 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) zf-CCHC PF00098.18 KFH47963.1 - 8.4e-08 31.7 1.2 1.5e-07 30.9 0.8 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 KFH47963.1 - 0.023 14.1 0.2 0.045 13.2 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF3166 PF11365.3 KFH47963.1 - 0.14 12.6 2.2 0.21 12.0 0.2 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3166) zf-CCHC_4 PF14392.1 KFH47963.1 - 0.18 11.5 0.6 0.4 10.3 0.4 1.6 1 0 0 1 1 1 0 Zinc knuckle BNIP2 PF12496.3 KFH47963.1 - 0.34 11.0 13.2 0.43 10.7 5.9 2.2 1 1 1 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 zf-C2H2 PF00096.21 KFH47964.1 - 1e-12 47.5 11.4 2.1e-06 27.7 0.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFH47964.1 - 2.5e-11 43.0 8.2 0.0001 22.3 3.6 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFH47964.1 - 4e-08 33.1 12.7 5.2e-07 29.6 3.4 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFH47964.1 - 1.6e-06 28.1 5.6 0.00029 20.8 0.7 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFH47964.1 - 3e-05 24.0 9.9 3.8e-05 23.7 0.2 2.8 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFH47964.1 - 0.00093 19.0 8.8 0.017 15.0 0.2 3.8 3 1 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KFH47964.1 - 0.59 10.2 4.2 9.1 6.4 0.4 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 KFH47964.1 - 0.94 9.2 7.1 0.76 9.5 1.6 2.3 1 1 1 2 2 2 0 BED zinc finger Elf1 PF05129.8 KFH47964.1 - 3 7.6 5.9 65 3.3 4.1 2.3 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-C2HC_2 PF13913.1 KFH47964.1 - 3.6 7.3 7.8 5.4 6.7 1.6 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Cast PF10174.4 KFH47965.1 - 0.0054 14.8 0.1 0.0085 14.2 0.0 1.2 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone DUF2383 PF09537.5 KFH47965.1 - 0.11 12.7 0.2 1.9 8.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Na_Ca_ex PF01699.19 KFH47966.1 - 1e-47 161.2 34.4 1.2e-24 86.5 4.2 3.3 3 0 0 3 3 3 2 Sodium/calcium exchanger protein MARVEL PF01284.18 KFH47966.1 - 0.0016 18.2 0.4 0.0016 18.2 0.2 3.7 2 1 1 3 3 3 1 Membrane-associating domain RRM_5 PF13893.1 KFH47967.1 - 9.9e-05 22.1 0.0 0.00016 21.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 KFH47967.1 - 0.0003 20.4 19.4 0.0017 17.9 0.6 3.8 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.17 KFH47967.1 - 0.0047 16.5 0.0 0.0074 15.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tachystatin_B PF11478.3 KFH47967.1 - 0.2 11.3 3.6 0.92 9.2 1.8 2.4 2 0 0 2 2 2 0 Antimicrobial chitin binding protein tachystatin B MCM PF00493.18 KFH47969.1 - 7.4e-135 449.0 0.0 1.3e-134 448.2 0.0 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KFH47969.1 - 5e-23 81.8 3.4 5.2e-23 81.8 1.0 2.1 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 KFH47969.1 - 1.5e-07 30.8 0.0 1.2e-05 24.5 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KFH47969.1 - 4.9e-06 26.3 0.0 2.6e-05 23.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 KFH47969.1 - 0.0071 16.7 0.1 0.04 14.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KFH47969.1 - 0.022 14.3 0.0 0.09 12.3 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) 7TMR-HDED PF07697.6 KFH47969.1 - 0.03 14.0 8.4 0.64 9.7 3.4 2.5 2 0 0 2 2 2 0 7TM-HD extracellular UPF0047 PF01894.12 KFH47970.1 - 3.7e-40 136.4 0.0 4.5e-40 136.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Ribosomal_L10 PF00466.15 KFH47971.1 - 1.1e-24 86.2 0.0 2.3e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 KFH47971.1 - 7.6e-17 61.4 9.6 8.3e-17 61.3 4.2 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein MFS_2 PF13347.1 KFH47972.1 - 4.3e-08 31.9 6.0 4.3e-08 31.9 4.2 2.6 3 0 0 3 3 3 1 MFS/sugar transport protein RRM_1 PF00076.17 KFH47973.1 - 2.9e-17 62.0 0.0 6.5e-17 60.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH47973.1 - 6.3e-13 48.4 0.0 1e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH47973.1 - 3.7e-06 26.6 0.0 7.1e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 KFH47973.1 - 3.2e-05 24.2 12.1 3.2e-05 24.2 8.4 3.1 3 1 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 HMG_box PF00505.14 KFH47974.1 - 3.7e-15 55.9 1.1 3.7e-15 55.9 0.8 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFH47974.1 - 5.1e-15 55.6 1.1 5.1e-15 55.6 0.8 1.9 2 0 0 2 2 2 1 HMG-box domain SAM_1 PF00536.25 KFH47974.1 - 1.5e-11 44.2 0.0 3.1e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFH47974.1 - 2e-09 37.1 0.3 6.4e-09 35.5 0.0 2.0 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) ScpA_ScpB PF02616.9 KFH47974.1 - 0.32 10.5 2.5 0.46 10.0 1.8 1.1 1 0 0 1 1 1 0 ScpA/B protein DltD_C PF04914.7 KFH47974.1 - 0.53 10.1 4.0 1 9.2 2.7 1.3 1 0 0 1 1 1 0 DltD C-terminal region ATP_bind_4 PF01902.12 KFH47975.1 - 2.4e-19 69.5 0.0 7.2e-14 51.6 0.0 2.9 2 1 0 2 2 2 2 ATP-binding region Ribonuc_L-PSP PF01042.16 KFH47975.1 - 7e-10 38.7 0.0 6e-06 26.0 0.0 3.5 3 1 0 3 3 3 2 Endoribonuclease L-PSP C2 PF00168.25 KFH47976.1 - 1.3e-72 239.6 0.3 5.7e-21 74.1 0.0 5.4 5 0 0 5 5 5 5 C2 domain DUF2404 PF10296.4 KFH47976.1 - 0.092 12.8 0.0 0.36 10.9 0.0 2.0 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) Fiji_64_capsid PF05880.6 KFH47976.1 - 0.13 10.6 0.1 0.23 9.7 0.0 1.3 1 0 0 1 1 1 0 Fijivirus 64 kDa capsid protein Cgr1 PF03879.9 KFH47977.1 - 4.7e-37 126.4 27.9 5.5e-37 126.2 19.3 1.0 1 0 0 1 1 1 1 Cgr1 family RR_TM4-6 PF06459.7 KFH47977.1 - 0.04 13.8 13.1 0.045 13.6 9.1 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PRP1_N PF06424.7 KFH47977.1 - 0.6 10.4 12.2 0.77 10.0 8.5 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal DUF2724 PF10893.3 KFH47977.1 - 0.83 9.5 3.9 3.3 7.6 2.7 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2724) Adeno_VII PF03228.9 KFH47977.1 - 2.3 8.8 11.4 3.2 8.3 7.9 1.2 1 0 0 1 1 1 0 Adenoviral core protein VII GAGA_bind PF06217.7 KFH47977.1 - 3.3 7.5 10.4 3.8 7.4 7.2 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family DRY_EERY PF09750.4 KFH47977.1 - 4.4 7.4 10.6 5.9 7.0 7.3 1.2 1 0 0 1 1 1 0 Alternative splicing regulator Birna_RdRp PF04197.7 KFH47977.1 - 6 4.7 9.4 6.8 4.5 6.5 1.0 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) DUF1764 PF08576.5 KFH47977.1 - 9.3 7.0 12.2 14 6.5 8.5 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) UQ_con PF00179.21 KFH47978.1 - 3.9e-32 110.5 0.0 4.8e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFH47978.1 - 4e-05 23.3 0.0 4.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B Glyco_transf_22 PF03901.12 KFH47979.1 - 5.3e-63 213.4 19.4 6.8e-63 213.1 13.5 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family FF PF01846.14 KFH47980.1 - 7.2e-49 163.5 13.9 7e-13 48.3 0.0 6.6 6 1 0 6 6 6 5 FF domain WW PF00397.21 KFH47980.1 - 1e-17 63.6 17.7 4.6e-09 35.9 4.6 2.7 2 0 0 2 2 2 2 WW domain tRNA-synt_1 PF00133.17 KFH47982.1 - 5.4e-219 728.1 0.8 2.9e-218 725.7 0.6 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KFH47982.1 - 8.5e-34 116.5 1.3 2.2e-33 115.2 0.9 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KFH47982.1 - 5.3e-15 54.9 0.1 4.8e-07 28.7 0.0 4.4 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 KFH47982.1 - 2e-13 50.0 0.8 8.3e-10 38.2 0.0 3.0 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 KFH47982.1 - 3.1e-05 23.9 7.1 3.1e-05 23.9 4.9 2.9 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm Amino_oxidase PF01593.19 KFH47983.1 - 2.4e-84 283.9 0.1 4.6e-84 283.0 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase HMG_box_2 PF09011.5 KFH47983.1 - 5.8e-10 39.4 8.1 5.8e-10 39.4 5.6 2.3 1 1 1 2 2 2 1 HMG-box domain SWIRM PF04433.12 KFH47983.1 - 7e-09 35.7 0.0 1.8e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain HMG_box PF00505.14 KFH47983.1 - 1.4e-08 34.8 12.2 9.8e-08 32.1 4.6 2.7 2 1 0 2 2 2 1 HMG (high mobility group) box NAD_binding_8 PF13450.1 KFH47983.1 - 3.4e-08 33.3 0.1 9.3e-08 31.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFH47983.1 - 0.0085 15.0 0.1 0.057 12.3 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KFH47983.1 - 0.068 12.9 0.0 0.58 9.9 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Hrs_helical PF12210.3 KFH47984.1 - 0.0093 16.1 1.3 0.41 10.9 0.1 2.5 2 0 0 2 2 2 1 Hepatocyte growth factor-regulated tyrosine kinase substrate YjcZ PF13990.1 KFH47984.1 - 0.025 13.7 0.2 0.04 13.0 0.2 1.3 1 0 0 1 1 1 0 YjcZ-like protein Med9 PF07544.8 KFH47984.1 - 0.039 13.6 2.7 0.23 11.1 0.1 2.5 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Fib_alpha PF08702.5 KFH47984.1 - 0.1 12.6 0.6 0.29 11.2 0.4 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family TMEM117 PF15113.1 KFH47984.1 - 0.15 10.5 0.3 0.22 10.0 0.2 1.1 1 0 0 1 1 1 0 TMEM117 protein family DUF948 PF06103.6 KFH47984.1 - 0.24 11.2 0.1 0.24 11.2 0.0 2.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF848 PF05852.6 KFH47984.1 - 0.32 10.8 3.4 0.93 9.3 0.8 2.1 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) TMF_TATA_bd PF12325.3 KFH47984.1 - 0.33 10.7 4.3 6.7 6.4 0.3 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding YscO PF07321.7 KFH47984.1 - 0.35 10.6 4.2 0.8 9.5 2.8 1.8 1 1 0 1 1 1 0 Type III secretion protein YscO DUF2721 PF11026.3 KFH47984.1 - 0.6 9.7 4.1 0.34 10.5 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF2077 PF09850.4 KFH47984.1 - 1.6 8.0 4.5 0.3 10.4 0.2 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) adh_short PF00106.20 KFH47985.1 - 1.1e-26 93.7 3.3 1.4e-26 93.3 2.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH47985.1 - 9.5e-22 77.9 0.6 1.1e-21 77.7 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH47985.1 - 2.7e-11 43.4 1.1 3.8e-11 42.9 0.8 1.2 1 0 0 1 1 1 1 KR domain HEM4 PF02602.10 KFH47985.1 - 0.048 12.9 0.2 0.073 12.2 0.1 1.2 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD 3HCDH_N PF02737.13 KFH47985.1 - 0.095 12.3 1.5 0.12 12.0 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KFH47985.1 - 0.14 12.6 1.7 0.2 12.1 0.2 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Glyco_transf_34 PF05637.7 KFH47986.1 - 8.3e-66 221.9 1.0 1.2e-65 221.3 0.7 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DEAD PF00270.24 KFH47987.1 - 3.9e-43 146.8 2.3 5.1e-43 146.4 1.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFH47987.1 - 1.1e-27 95.6 0.3 6.2e-27 93.2 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFH47987.1 - 0.00035 20.4 0.0 0.00077 19.3 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KFH47987.1 - 0.00064 19.3 0.1 0.0018 17.8 0.0 1.7 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KFH47987.1 - 0.012 15.7 0.1 0.043 13.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KFH47987.1 - 0.033 13.9 0.0 0.1 12.3 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Flavi_DEAD PF07652.9 KFH47987.1 - 0.064 13.0 0.2 0.3 10.8 0.1 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain tRNA-synt_1b PF00579.20 KFH47987.1 - 0.064 12.3 0.2 0.29 10.2 0.0 2.1 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) UvrD-helicase PF00580.16 KFH47987.1 - 0.1 11.9 0.2 0.15 11.2 0.1 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain Fanconi_A PF03511.9 KFH47987.1 - 0.1 12.3 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Fanconi anaemia group A protein zf-CSL PF05207.8 KFH47988.1 - 5.4e-16 57.8 0.4 8.8e-16 57.1 0.2 1.4 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 KFH47988.1 - 1.4e-12 47.1 0.1 2.2e-12 46.5 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain IN_DBD_C PF00552.16 KFH47988.1 - 0.12 11.8 0.1 0.22 10.9 0.1 1.4 1 0 0 1 1 1 0 Integrase DNA binding domain Anp1 PF03452.9 KFH47989.1 - 1.4e-108 362.1 0.0 1.9e-108 361.7 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 KFH47989.1 - 0.0073 16.0 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 HAD_2 PF13419.1 KFH47990.1 - 1.9e-11 44.5 0.0 2.7e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFH47990.1 - 7.7e-10 38.3 0.0 1.3e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KFH47990.1 - 9.7e-09 35.9 0.0 2e-08 34.9 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFH47990.1 - 0.00063 19.9 0.0 0.00086 19.5 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase GHL6 PF14871.1 KFH47990.1 - 0.037 14.0 0.2 0.082 12.9 0.0 1.6 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 DUF2834 PF11196.3 KFH47991.1 - 0.011 15.8 2.3 2 8.6 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2834) DUF1771 PF08590.5 KFH47992.1 - 2.4e-13 49.8 10.9 2.4e-13 49.8 7.6 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF1771) Smr PF01713.16 KFH47992.1 - 7.4e-10 38.8 0.0 2.6e-09 37.1 0.0 2.0 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.19 KFH47992.1 - 6.4e-09 35.2 3.9 0.0007 19.2 0.2 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HBS1_N PF08938.5 KFH47992.1 - 0.00024 21.1 0.2 0.0021 18.1 0.0 2.4 2 0 0 2 2 2 1 HBS1 N-terminus CUE PF02845.11 KFH47992.1 - 0.18 11.3 0.0 0.51 9.8 0.0 1.8 2 0 0 2 2 2 0 CUE domain DUF2346 PF09803.4 KFH47993.1 - 0.0004 20.1 5.7 0.0012 18.6 3.8 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) Cas_Csy4 PF09618.5 KFH47993.1 - 0.14 11.9 0.1 0.17 11.7 0.0 1.0 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) Skp1 PF01466.14 KFH47995.1 - 5.6e-40 135.2 1.4 5.6e-40 135.2 1.0 1.7 3 0 0 3 3 3 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KFH47995.1 - 3.1e-19 68.8 1.1 6.7e-19 67.7 0.0 2.1 3 0 0 3 3 3 1 Skp1 family, tetramerisation domain DUF4375 PF14300.1 KFH47995.1 - 0.0034 17.3 1.3 0.0044 17.0 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4375) Guanylate_cyc PF00211.15 KFH47996.1 - 0.12 11.7 0.2 0.4 10.0 0.1 1.8 2 0 0 2 2 2 0 Adenylate and Guanylate cyclase catalytic domain Sec1 PF00995.18 KFH47998.1 - 5.2e-138 461.1 0.0 5.9e-138 460.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DGCR6 PF07324.6 KFH47998.1 - 0.015 14.8 1.1 0.61 9.5 0.2 2.5 2 0 0 2 2 2 0 DiGeorge syndrome critical region 6 (DGCR6) protein FAD_binding_2 PF00890.19 KFH48000.1 - 1.2e-123 413.0 2.2 1.5e-123 412.7 1.6 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 KFH48000.1 - 3.7e-46 156.1 0.2 5.5e-46 155.5 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.12 KFH48000.1 - 3.2e-06 26.4 0.2 0.0039 16.3 0.0 2.4 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.9 KFH48000.1 - 1.4e-05 25.1 0.0 0.033 14.0 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KFH48000.1 - 0.00013 20.9 0.5 0.039 12.8 0.8 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 KFH48000.1 - 0.00088 18.2 0.2 0.0048 15.8 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KFH48000.1 - 0.0097 14.9 0.5 0.022 13.8 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain DUF600 PF04634.7 KFH48000.1 - 0.014 15.4 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF600 HI0933_like PF03486.9 KFH48000.1 - 0.12 10.7 1.0 0.54 8.6 0.3 2.1 2 0 0 2 2 2 0 HI0933-like protein Glyco_hydro_38 PF01074.17 KFH48001.1 - 9.8e-89 297.2 0.2 1.5e-88 296.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 KFH48001.1 - 5.3e-68 229.8 0.0 8.9e-68 229.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 KFH48001.1 - 1.4e-25 89.3 0.0 2.6e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase, middle domain CorA PF01544.13 KFH48002.1 - 7.2e-40 136.8 1.4 1e-38 133.0 1.0 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein ORC6 PF05460.8 KFH48002.1 - 3.8 6.5 8.7 8.9 5.3 6.0 1.6 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Herpes_DNAp_acc PF04929.7 KFH48002.1 - 7.6 5.3 6.8 15 4.4 4.7 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor R3H PF01424.17 KFH48003.1 - 8.9e-15 54.1 0.8 1.9e-14 53.0 0.5 1.6 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 KFH48003.1 - 0.00078 19.3 32.3 0.0022 17.8 7.2 15.4 16 1 0 16 16 16 7 NF-X1 type zinc finger Abhydrolase_6 PF12697.2 KFH48004.1 - 1.5e-15 57.7 1.2 1.9e-15 57.3 0.4 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH48004.1 - 1.2e-14 54.2 0.0 2.2e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KFH48004.1 - 4.9e-06 26.2 0.0 9.2e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 KFH48004.1 - 8.1e-06 25.5 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFH48004.1 - 0.005 16.0 0.0 0.13 11.4 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KFH48004.1 - 0.022 14.2 0.0 0.097 12.1 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.2 KFH48004.1 - 0.046 12.6 0.0 0.072 11.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Esterase PF00756.15 KFH48004.1 - 0.084 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Peptidase_M24 PF00557.19 KFH48005.1 - 3.5e-11 43.0 0.0 4.8e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 SapB_1 PF05184.10 KFH48005.1 - 0.026 14.3 0.4 0.16 11.7 0.0 2.4 2 0 0 2 2 2 0 Saposin-like type B, region 1 BORG_CEP PF14957.1 KFH48006.1 - 0.21 12.4 2.3 0.44 11.4 1.6 1.4 1 0 0 1 1 1 0 Cdc42 effector NPR3 PF03666.8 KFH48006.1 - 2.2 6.7 4.2 3.4 6.1 2.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 zf-C2H2_4 PF13894.1 KFH48006.1 - 3.2 8.3 17.4 4.4 7.8 1.4 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger HMG_box PF00505.14 KFH48007.1 - 6.4e-25 87.2 1.6 8.6e-25 86.8 1.1 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFH48007.1 - 6e-19 68.1 2.1 7.8e-19 67.8 1.5 1.2 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 KFH48007.1 - 0.00067 19.4 0.8 0.0014 18.3 0.5 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box 5 DUF1014 PF06244.7 KFH48007.1 - 0.064 13.4 0.1 0.14 12.3 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1014) Dpy-30 PF05186.8 KFH48008.1 - 5.7e-06 25.7 0.0 8.4e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Dpy-30 motif Shisa PF13908.1 KFH48008.1 - 2.8 8.0 5.3 3.7 7.7 3.7 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4106 PF13388.1 KFH48008.1 - 4.5 6.1 6.4 4.8 6.0 4.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) ATP_bind_1 PF03029.12 KFH48010.1 - 5.5e-73 245.4 0.0 8.5e-73 244.7 0.0 1.3 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 KFH48010.1 - 0.00018 22.3 0.0 0.00042 21.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KFH48010.1 - 0.0026 17.6 0.0 0.0052 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KFH48010.1 - 0.0031 17.0 0.0 0.0059 16.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RNA_helicase PF00910.17 KFH48010.1 - 0.0084 16.2 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.1 KFH48010.1 - 0.0084 15.9 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KFH48010.1 - 0.01 15.2 0.0 0.027 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA-like domain AAA_31 PF13614.1 KFH48010.1 - 0.012 15.5 0.1 0.062 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KFH48010.1 - 0.012 15.7 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 KFH48010.1 - 0.019 14.6 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KFH48010.1 - 0.035 14.4 0.0 0.081 13.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.1 KFH48010.1 - 0.037 13.4 0.4 0.23 10.8 0.2 2.3 2 1 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 KFH48010.1 - 0.04 13.3 0.0 7.2 6.0 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 KFH48010.1 - 0.067 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 KFH48010.1 - 0.099 12.4 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain MMR_HSR1 PF01926.18 KFH48010.1 - 0.11 12.4 0.0 0.29 11.1 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase SRP54 PF00448.17 KFH48010.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DRMBL PF07522.9 KFH48012.1 - 5.2e-32 110.1 0.0 8.9e-32 109.3 0.0 1.4 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 KFH48012.1 - 1e-12 48.0 0.0 2.1e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KFH48012.1 - 0.0051 16.4 0.1 0.012 15.3 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily PGM_PMM_I PF02878.11 KFH48013.1 - 5.8e-34 116.5 0.0 8.8e-34 115.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 KFH48013.1 - 1.1e-24 86.5 0.0 2.5e-24 85.4 0.0 1.6 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 KFH48013.1 - 1.7e-16 60.4 0.0 3.6e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KFH48013.1 - 9.8e-09 35.1 0.0 2.3e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain GPI-anchored PF10342.4 KFH48014.1 - 3.5e-21 75.4 0.2 3.5e-21 75.4 0.2 2.2 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family zf-RING_2 PF13639.1 KFH48016.1 - 0.00039 20.1 8.6 0.00039 20.1 6.0 2.4 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFH48016.1 - 0.011 15.4 4.9 0.011 15.4 3.4 2.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFH48016.1 - 0.043 13.9 3.8 0.14 12.3 2.6 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger DUF4611 PF15387.1 KFH48016.1 - 0.18 11.9 3.8 0.43 10.7 2.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) zf-Apc11 PF12861.2 KFH48016.1 - 0.79 9.5 7.8 0.21 11.4 2.1 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Peptidase_M76 PF09768.4 KFH48017.1 - 5.6e-68 227.7 1.9 7e-68 227.4 1.3 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 KFH48017.1 - 0.0053 16.4 3.0 0.0053 16.4 2.1 1.9 1 1 1 2 2 2 1 SprT-like family Cys_knot PF00007.17 KFH48017.1 - 0.03 14.3 1.6 0.94 9.5 0.4 2.3 2 0 0 2 2 2 0 Cystine-knot domain Peptidase_MA_2 PF13485.1 KFH48017.1 - 0.11 12.5 0.1 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase MA superfamily DUF2268 PF10026.4 KFH48017.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) DUF1996 PF09362.5 KFH48018.1 - 1.1e-58 198.6 0.3 2e-58 197.8 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 KFH48018.1 - 9.2e-18 63.9 6.8 1.9e-17 62.9 4.7 1.6 1 0 0 1 1 1 1 WSC domain Med3 PF11593.3 KFH48018.1 - 4 6.5 6.6 5.9 6.0 4.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF1183 PF06682.7 KFH48019.1 - 2.1e-77 260.8 4.6 2.6e-77 260.5 3.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) TauE PF01925.14 KFH48019.1 - 0.0073 15.7 1.7 0.0073 15.7 1.2 2.0 2 0 0 2 2 2 1 Sulfite exporter TauE/SafE DUF4381 PF14316.1 KFH48019.1 - 0.068 13.2 0.3 0.12 12.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Pex2_Pex12 PF04757.9 KFH48021.1 - 3.7e-44 150.8 5.0 4.8e-44 150.4 3.4 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 KFH48021.1 - 1.1e-12 47.5 8.0 1.8e-12 46.8 5.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFH48021.1 - 3e-12 46.3 7.6 4.6e-12 45.7 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFH48021.1 - 4.8e-10 38.9 6.5 7.4e-10 38.3 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFH48021.1 - 5e-10 38.8 5.8 7.8e-10 38.2 4.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFH48021.1 - 1.5e-08 34.2 5.5 2.3e-08 33.6 3.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFH48021.1 - 8.5e-07 28.7 7.7 1.3e-06 28.1 5.3 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 KFH48021.1 - 1.9e-05 24.3 2.2 3.7e-05 23.4 1.6 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 KFH48021.1 - 5.4e-05 23.2 6.7 0.00011 22.1 4.6 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KFH48021.1 - 0.00023 20.8 4.4 0.00043 19.9 3.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 KFH48021.1 - 0.0025 17.2 1.4 0.0043 16.5 1.0 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 KFH48021.1 - 0.036 13.8 2.4 0.062 13.1 1.7 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KFH48021.1 - 0.067 12.7 8.4 0.12 11.9 5.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TerY-C PF15616.1 KFH48021.1 - 0.098 12.5 2.2 0.17 11.8 1.5 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain IBR PF01485.16 KFH48021.1 - 2.3 8.1 7.8 7.3 6.5 5.4 1.7 1 1 0 1 1 1 0 IBR domain Abhydrolase_5 PF12695.2 KFH48022.1 - 2e-22 79.5 0.0 2.9e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFH48022.1 - 2.5e-16 60.2 0.0 1.2e-14 54.7 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KFH48022.1 - 2.2e-05 23.1 0.0 0.079 11.4 0.0 3.2 3 1 1 4 4 4 2 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 KFH48022.1 - 7.7e-05 22.3 0.0 0.053 13.0 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF818 PF05677.7 KFH48022.1 - 0.00017 20.4 0.0 0.00024 19.9 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.11 KFH48022.1 - 0.00027 20.4 0.0 0.12 11.8 0.0 2.2 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase FSH1 PF03959.8 KFH48022.1 - 0.00076 18.9 0.0 0.0016 17.9 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 KFH48022.1 - 0.00095 18.4 0.0 0.0061 15.8 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.6 KFH48022.1 - 0.0052 16.5 0.0 0.2 11.3 0.0 2.4 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 KFH48022.1 - 0.014 14.9 0.0 0.029 13.9 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.13 KFH48022.1 - 0.016 14.5 0.0 0.86 8.8 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S15 PF02129.13 KFH48022.1 - 0.14 11.5 0.0 6.2 6.1 0.0 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Glyco_hydro_53 PF07745.8 KFH48023.1 - 7.5e-108 360.2 0.0 8.4e-108 360.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Cellulase PF00150.13 KFH48023.1 - 0.0098 15.1 0.1 0.018 14.2 0.0 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4015 PF13200.1 KFH48023.1 - 0.029 13.3 0.0 0.044 12.6 0.0 1.2 1 0 0 1 1 1 0 Putative glycosyl hydrolase domain MFS_1 PF07690.11 KFH48024.1 - 2e-37 128.7 41.9 2e-37 128.7 29.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH48024.1 - 0.71 8.3 30.1 6.3 5.2 20.8 2.3 1 1 0 1 1 1 0 Sugar (and other) transporter UCH PF00443.24 KFH48025.1 - 3.8e-41 140.9 0.0 1.9e-35 122.3 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFH48025.1 - 4.1e-13 49.4 0.0 1.3e-08 34.6 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Glyoxal_oxid_N PF07250.6 KFH48026.1 - 2.7e-29 101.9 0.0 2e-27 95.8 0.0 3.2 3 1 1 4 4 4 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 KFH48026.1 - 1.3e-22 79.7 0.0 2.4e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) WSC PF01822.14 KFH48026.1 - 3.7e-14 52.3 3.8 6.8e-14 51.5 2.6 1.4 1 0 0 1 1 1 1 WSC domain Rax2 PF12768.2 KFH48027.1 - 1.2e-87 293.6 0.3 2.6e-78 263.0 0.0 4.1 3 1 0 3 3 3 3 Cortical protein marker for cell polarity Kelch_4 PF13418.1 KFH48027.1 - 0.017 14.9 0.6 2.2 8.1 0.0 3.8 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_3 PF13415.1 KFH48027.1 - 0.028 14.5 4.3 0.35 11.1 0.1 4.3 4 0 0 4 4 4 0 Galactose oxidase, central domain Caps_synth PF05704.7 KFH48028.1 - 7.9e-14 51.4 0.0 1.2e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 KFH48028.1 - 3.1e-06 27.5 0.0 5.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KFH48028.1 - 0.067 11.6 0.1 0.1 11.0 0.1 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain DUF2361 PF10153.4 KFH48029.1 - 1.2e-33 115.6 7.3 3e-33 114.4 5.1 1.7 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2361) LRV_FeS PF05484.6 KFH48029.1 - 0.043 13.3 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 LRV protein FeS4 cluster Ribosomal_S19 PF00203.16 KFH48030.1 - 7.8e-34 115.1 0.2 1.1e-33 114.6 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 DUF462 PF04315.7 KFH48030.1 - 0.054 12.8 0.0 4.8 6.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF462 FAD_binding_6 PF00970.19 KFH48032.1 - 2.4e-27 94.9 0.0 3.7e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KFH48032.1 - 6.9e-26 90.9 0.0 1e-25 90.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KFH48032.1 - 0.00021 21.2 0.0 0.025 14.4 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KFH48032.1 - 0.092 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain ATG11 PF10377.4 KFH48034.1 - 1.7e-39 134.6 0.5 1.7e-39 134.6 0.3 3.6 4 0 0 4 4 4 1 Autophagy-related protein 11 Cleaved_Adhesin PF07675.6 KFH48034.1 - 0.00016 21.3 0.1 0.00042 19.9 0.1 1.7 1 0 0 1 1 1 1 Cleaved Adhesin Domain APG17 PF04108.7 KFH48034.1 - 0.0032 16.3 4.2 0.0032 16.3 2.9 6.5 4 2 2 6 6 6 3 Autophagy protein Apg17 Reo_sigmaC PF04582.7 KFH48034.1 - 0.0037 16.5 3.1 0.0037 16.5 2.2 5.5 3 1 1 5 5 5 2 Reovirus sigma C capsid protein ELF PF03317.8 KFH48034.1 - 2.6 7.2 9.9 0.086 12.1 1.0 2.3 2 0 0 2 2 2 0 ELF protein P34-Arc PF04045.9 KFH48035.1 - 3.7e-94 314.5 0.4 5.7e-94 313.9 0.3 1.2 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc MaoC_dehydratas PF01575.14 KFH48036.1 - 7.2e-20 70.6 0.0 1e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 KFH48036.1 - 0.00043 20.0 0.0 0.6 9.9 0.0 2.7 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase 4HBT PF03061.17 KFH48036.1 - 0.022 14.8 0.0 0.053 13.6 0.0 1.7 1 0 0 1 1 1 0 Thioesterase superfamily DUF1762 PF08574.5 KFH48037.1 - 0.0066 16.8 0.4 0.0066 16.8 0.3 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF1762) DUF3453 PF11935.3 KFH48038.1 - 1.9e-65 220.6 0.0 3.1e-65 219.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) CH PF00307.26 KFH48039.1 - 2.8e-11 43.4 0.0 4.1e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Herpes_TK PF00693.13 KFH48039.1 - 0.19 10.8 0.8 0.34 10.0 0.5 1.3 1 0 0 1 1 1 0 Thymidine kinase from herpesvirus Complex1_49kDa PF00346.14 KFH48040.1 - 2.8e-134 446.3 0.0 3.7e-134 445.9 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.14 KFH48040.1 - 0.19 10.4 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 Nickel-dependent hydrogenase RRM_1 PF00076.17 KFH48041.1 - 4e-25 87.2 0.3 1.7e-10 40.3 0.0 3.5 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH48041.1 - 3.3e-18 65.4 0.0 2.2e-06 27.5 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH48041.1 - 1.2e-13 50.6 0.0 5.5e-07 29.3 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) His_Phos_1 PF00300.17 KFH48042.1 - 7e-25 87.9 0.0 1e-24 87.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RRM_1 PF00076.17 KFH48043.1 - 1.5e-14 53.3 0.1 5e-10 38.8 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH48043.1 - 8.4e-12 44.7 0.0 6.6e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH48043.1 - 6.6e-10 38.8 0.0 5.3e-07 29.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RNA_pol_Rpc4 PF05132.9 KFH48043.1 - 0.34 10.8 0.1 0.34 10.8 0.0 3.9 2 1 0 2 2 2 0 RNA polymerase III RPC4 Lin-8 PF03353.10 KFH48043.1 - 2.1 7.5 18.1 3.6 6.7 12.6 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Acetyltransf_3 PF13302.1 KFH48044.1 - 7.2e-28 97.5 0.0 9.1e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFH48044.1 - 5.9e-07 29.4 0.0 1.4e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 KFH48044.1 - 3.4e-05 23.7 0.0 4.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KFH48044.1 - 0.00047 20.1 0.0 0.00081 19.3 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF1649 PF07855.7 KFH48045.1 - 4.6e-57 192.2 0.0 5.6e-57 191.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) DUF377 PF04041.8 KFH48045.1 - 0.12 11.0 0.1 0.59 8.7 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF377) Mo-co_dimer PF03404.11 KFH48045.1 - 0.29 10.7 2.4 0.52 9.9 1.6 1.5 1 1 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain LSM PF01423.17 KFH48046.1 - 3e-16 58.7 1.2 4.1e-16 58.2 0.8 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KFH48046.1 - 0.013 15.4 0.1 0.02 14.8 0.1 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain LSM14 PF12701.2 KFH48046.1 - 0.13 12.0 0.2 0.19 11.5 0.1 1.3 1 1 0 1 1 1 0 Scd6-like Sm domain KH_1 PF00013.24 KFH48049.1 - 1.5e-37 126.9 12.0 3.2e-14 52.2 0.1 3.1 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KFH48049.1 - 7.3e-30 102.0 13.2 2.9e-11 42.7 0.7 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KFH48049.1 - 6.1e-10 38.5 7.7 0.014 14.9 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KFH48049.1 - 1.4e-07 31.0 2.6 0.091 12.4 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 KFH48049.1 - 0.00017 21.2 4.1 0.68 9.7 0.0 3.3 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 KFH48049.1 - 0.0069 15.8 0.4 1 8.8 0.0 3.1 3 0 0 3 3 3 1 dUTPase EF-hand_4 PF12763.2 KFH48050.1 - 5.2e-26 90.4 0.0 3.8e-14 52.2 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.6 KFH48050.1 - 0.00067 19.6 25.7 0.00067 19.6 17.8 5.5 5 1 2 7 7 7 4 Domain of unknown function (DUF1720) EF-hand_6 PF13405.1 KFH48050.1 - 0.0021 17.7 0.1 0.88 9.6 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 KFH48050.1 - 0.0022 18.0 0.1 0.25 11.5 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair FlxA PF14282.1 KFH48050.1 - 3.2 7.7 41.3 0.48 10.4 0.5 4.6 2 2 2 4 4 4 0 FlxA-like protein LRR_4 PF12799.2 KFH48051.1 - 4.7e-17 61.1 0.6 1.5e-05 24.4 0.3 4.7 5 0 0 5 5 5 4 Leucine Rich repeats (2 copies) CAP_GLY PF01302.20 KFH48051.1 - 1.3e-13 50.4 0.4 3.2e-13 49.1 0.1 1.8 2 0 0 2 2 2 1 CAP-Gly domain LRR_8 PF13855.1 KFH48051.1 - 6.8e-10 38.5 6.0 3.2e-05 23.5 0.3 4.0 3 2 2 5 5 5 3 Leucine rich repeat LRR_1 PF00560.28 KFH48051.1 - 2.4e-07 29.8 4.6 23 5.5 0.0 6.8 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_7 PF13504.1 KFH48051.1 - 0.00025 20.7 7.6 23 5.7 0.2 6.8 7 1 0 7 7 7 0 Leucine rich repeat LRR_6 PF13516.1 KFH48051.1 - 0.00031 20.4 10.4 0.63 10.2 0.0 6.0 6 1 1 7 7 7 2 Leucine Rich repeat LRR_9 PF14580.1 KFH48051.1 - 0.083 12.4 0.2 22 4.5 0.0 2.7 1 1 0 3 3 3 0 Leucine-rich repeat DEAD PF00270.24 KFH48052.1 - 8e-32 110.0 0.1 2.4e-31 108.5 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFH48052.1 - 7e-18 64.2 0.1 1.4e-17 63.2 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFH48052.1 - 0.00027 20.8 0.0 0.00055 19.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KFH48052.1 - 0.017 13.8 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain SecA_DEAD PF07517.9 KFH48052.1 - 0.072 12.3 0.0 11 5.2 0.0 2.3 2 1 0 2 2 2 0 SecA DEAD-like domain DUF1253 PF06862.7 KFH48052.1 - 0.25 9.7 0.5 2.4 6.4 0.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1253) APH PF01636.18 KFH48053.1 - 1.9e-40 139.0 0.0 2.7e-40 138.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KFH48053.1 - 1.2e-07 31.2 0.0 5.5e-07 29.0 0.0 1.9 1 1 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 KFH48053.1 - 0.00011 21.8 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 KFH48053.1 - 0.00047 19.2 0.0 0.0019 17.2 0.0 1.9 1 1 0 1 1 1 1 Fructosamine kinase RIO1 PF01163.17 KFH48053.1 - 0.0019 17.5 0.0 0.13 11.5 0.0 2.2 2 0 0 2 2 2 1 RIO1 family DUF1679 PF07914.6 KFH48053.1 - 0.11 11.0 0.1 0.45 9.0 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) HEAT_2 PF13646.1 KFH48054.1 - 0.00038 20.6 12.3 0.019 15.2 0.3 5.9 6 1 1 7 7 7 3 HEAT repeats HEAT PF02985.17 KFH48054.1 - 0.0017 18.3 1.1 0.27 11.4 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 KFH48054.1 - 0.026 15.0 0.1 0.026 15.0 0.1 4.9 6 0 0 6 6 6 0 HEAT-like repeat DUF2570 PF10828.3 KFH48054.1 - 0.23 11.0 2.6 0.69 9.5 1.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) DSPc PF00782.15 KFH48055.1 - 1.9e-24 85.7 0.0 4.1e-21 74.9 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFH48055.1 - 0.012 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Mt_ATP-synt_B PF05405.9 KFH48056.1 - 4.6e-53 179.0 7.9 6e-53 178.6 5.5 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF1539 PF07560.6 KFH48056.1 - 0.082 12.7 3.1 0.048 13.5 0.7 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) NPV_P10 PF05531.7 KFH48056.1 - 0.39 11.0 6.0 4.5 7.6 4.1 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Cullin PF00888.17 KFH48057.1 - 1.7e-134 449.5 0.4 2.1e-134 449.2 0.2 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KFH48057.1 - 4.7e-27 93.6 2.2 4.9e-27 93.5 0.2 2.1 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF3259 PF11652.3 KFH48058.1 - 0.088 12.9 0.2 0.2 11.8 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3259) Ctr PF04145.10 KFH48059.1 - 2.9e-37 127.9 8.2 3.6e-37 127.5 5.7 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Sigma_1s PF02454.11 KFH48059.1 - 0.062 13.0 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 Sigma 1s protein DUF962 PF06127.6 KFH48059.1 - 0.15 12.0 2.7 0.51 10.2 1.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF962) DUF4131 PF13567.1 KFH48059.1 - 0.48 9.8 4.6 2.3 7.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) mRNA_cap_enzyme PF01331.14 KFH48061.1 - 8.8e-52 175.5 0.2 1.3e-51 175.0 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 KFH48061.1 - 3.8e-20 72.1 0.0 7.3e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 KFH48061.1 - 1.8e-06 27.4 0.1 5.9e-05 22.5 0.1 2.5 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Pkinase PF00069.20 KFH48062.1 - 3.7e-68 229.4 0.0 5e-68 229.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH48062.1 - 2.6e-42 144.6 0.0 3.7e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH48062.1 - 3.4e-06 26.2 0.0 1.2e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFH48062.1 - 0.0014 17.6 0.1 0.0025 16.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KFH48062.1 - 0.014 14.7 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 KFH48062.1 - 0.031 14.0 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 KFH48062.1 - 0.042 13.1 0.3 0.21 10.9 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Sybindin PF04099.7 KFH48064.1 - 2.6e-16 59.6 0.0 2.1e-14 53.4 0.0 2.1 2 0 0 2 2 2 2 Sybindin-like family AA_kinase PF00696.23 KFH48065.1 - 6.3e-39 133.9 1.3 9e-39 133.4 0.9 1.1 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 KFH48065.1 - 1.2e-16 60.1 1.5 4.2e-16 58.4 0.1 2.3 2 0 0 2 2 2 1 PUA domain Methyltransf_26 PF13659.1 KFH48066.1 - 2.6e-17 62.9 0.0 3.5e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFH48066.1 - 0.00088 18.6 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MSC PF09402.5 KFH48067.1 - 8.8e-101 336.9 0.0 1.2e-100 336.4 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 KFH48067.1 - 1e-15 56.9 0.0 1.9e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 HeH/LEM domain Thymopoietin PF08198.6 KFH48067.1 - 0.01 15.3 0.0 0.029 13.8 0.0 1.7 1 0 0 1 1 1 0 Thymopoietin protein DUF3350 PF11830.3 KFH48067.1 - 0.12 12.3 5.1 4.6 7.3 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3350) RabGAP-TBC PF00566.13 KFH48068.1 - 5.3e-30 104.4 2.1 1.2e-29 103.2 1.4 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Myb_DNA-binding PF00249.26 KFH48069.1 - 3.4e-07 30.1 0.0 6.6e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFH48069.1 - 0.0026 17.8 0.0 0.0061 16.6 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain OmpH PF03938.9 KFH48069.1 - 0.33 10.8 5.1 0.1 12.5 0.1 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) CBFB_NFYA PF02045.10 KFH48070.1 - 1.7e-30 105.2 4.8 3.4e-30 104.3 3.3 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.7 KFH48070.1 - 0.069 12.0 0.0 0.092 11.6 0.0 1.2 1 0 0 1 1 1 0 Hus1-like protein SF3b1 PF08920.5 KFH48071.1 - 6.1e-35 120.3 0.4 6.1e-35 120.3 0.3 2.4 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 KFH48071.1 - 1.8e-15 56.9 2.2 0.01 16.1 0.0 7.3 6 3 3 9 9 9 6 HEAT repeats HEAT PF02985.17 KFH48071.1 - 4.5e-12 44.9 7.7 0.98 9.6 0.0 9.5 10 0 0 10 10 10 3 HEAT repeat HEAT_EZ PF13513.1 KFH48071.1 - 1.9e-11 44.0 1.1 0.79 10.2 0.0 8.7 7 2 2 9 9 9 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KFH48071.1 - 4.4e-06 27.0 0.1 0.49 10.8 0.0 5.6 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 KFH48071.1 - 2.3e-05 22.9 0.6 0.0047 15.3 0.1 3.2 2 2 1 3 3 3 1 Adaptin N terminal region UPF0236 PF06782.6 KFH48071.1 - 0.0023 16.4 0.1 0.0023 16.4 0.1 1.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0236) NUC173 PF08161.7 KFH48071.1 - 0.0092 15.3 0.1 5.8 6.2 0.0 3.6 3 0 0 3 3 3 1 NUC173 domain CLASP_N PF12348.3 KFH48071.1 - 0.014 14.7 0.1 1.4 8.2 0.0 3.6 4 0 0 4 4 4 0 CLASP N terminal Dopey_N PF04118.9 KFH48071.1 - 0.3 9.8 0.4 21 3.7 0.0 3.6 5 0 0 5 5 5 0 Dopey, N-terminal Sensor PF13796.1 KFH48073.1 - 0.096 12.2 0.2 0.31 10.6 0.1 1.8 1 0 0 1 1 1 0 Putative sensor NUDIX PF00293.23 KFH48075.1 - 9.1e-12 44.7 0.0 1.4e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain CPSase_L_D2 PF02786.12 KFH48076.1 - 6.1e-81 270.7 0.1 9.3e-81 270.1 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 KFH48076.1 - 3.4e-65 219.1 0.0 5.6e-65 218.4 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 KFH48076.1 - 9.1e-35 119.1 0.0 1.9e-34 118.0 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain HMGL-like PF00682.14 KFH48076.1 - 5.1e-27 95.0 0.0 9.3e-27 94.1 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_carb_C PF02785.14 KFH48076.1 - 5.4e-21 74.5 0.0 4.3e-11 42.7 0.0 3.1 3 0 0 3 3 2 2 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 KFH48076.1 - 1.9e-20 73.3 0.1 3.9e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KFH48076.1 - 1.2e-18 66.4 3.1 1.3e-18 66.4 0.9 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 KFH48076.1 - 7.4e-15 54.5 0.0 3.5e-14 52.2 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 KFH48076.1 - 2.3e-12 46.3 0.8 1.9e-07 30.6 0.0 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 KFH48076.1 - 2.9e-10 39.9 0.0 5e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KFH48076.1 - 2e-07 30.5 0.0 3.8e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD_2 PF12700.2 KFH48076.1 - 9.8e-07 28.2 0.1 0.0036 16.5 0.0 2.2 1 1 1 2 2 2 2 HlyD family secretion protein RimK PF08443.6 KFH48076.1 - 1.9e-06 27.4 0.0 8.6e-06 25.3 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD PF00529.15 KFH48076.1 - 4e-05 23.0 0.1 0.0036 16.6 0.0 2.4 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_3 PF13437.1 KFH48076.1 - 4.3e-05 23.8 0.0 0.0019 18.5 0.1 2.7 1 1 1 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.9 KFH48076.1 - 7.3e-05 22.6 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain NQRA PF05896.6 KFH48076.1 - 0.0031 16.7 0.2 0.0056 15.9 0.1 1.3 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) DUF2118 PF09891.4 KFH48076.1 - 0.0064 16.2 0.0 0.019 14.6 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) RnfC_N PF13375.1 KFH48076.1 - 0.019 14.6 0.5 0.049 13.3 0.3 1.7 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain GARS_A PF01071.14 KFH48076.1 - 0.061 12.8 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Nitroreductase PF00881.19 KFH48076.1 - 0.11 12.2 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Nitroreductase family GCV_H PF01597.14 KFH48076.1 - 0.2 11.3 0.2 0.64 9.7 0.1 1.8 1 1 0 1 1 1 0 Glycine cleavage H-protein ThiF PF00899.16 KFH48077.1 - 2.4e-37 127.8 0.3 5.4e-37 126.6 0.1 1.6 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 KFH48077.1 - 9.4e-26 89.3 0.1 2e-25 88.3 0.0 1.6 2 0 0 2 2 2 1 E2 binding domain UBACT PF02134.16 KFH48077.1 - 7e-25 86.3 0.6 3.7e-24 84.0 0.1 2.2 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KFH48077.1 - 1.8e-14 52.8 2.7 1.8e-14 52.8 1.8 1.9 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 KFH48077.1 - 2.2e-05 24.6 0.0 9.7e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 KFH48077.1 - 0.095 12.4 0.1 3.3 7.4 0.0 2.5 1 1 1 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.13 KFH48077.1 - 0.13 12.2 0.0 0.38 10.7 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain MFS_1 PF07690.11 KFH48078.1 - 4.5e-31 107.8 33.1 6.7e-31 107.2 22.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH48078.1 - 1.5e-10 40.3 5.1 1.5e-10 40.3 3.5 3.4 2 1 2 4 4 4 1 Sugar (and other) transporter DUF2839 PF10999.3 KFH48078.1 - 0.23 11.5 1.7 0.37 10.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) DUF1191 PF06697.7 KFH48079.1 - 0.12 11.1 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) S-AdoMet_synt_C PF02773.11 KFH48080.1 - 2.6e-74 247.4 0.3 4.2e-74 246.7 0.2 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 KFH48080.1 - 1.5e-47 160.5 0.0 2.5e-47 159.7 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 KFH48080.1 - 1.6e-42 143.8 0.7 3e-42 142.8 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Sel1 PF08238.7 KFH48081.1 - 5.1e-13 49.2 10.3 0.00081 19.9 0.7 4.4 4 0 0 4 4 4 3 Sel1 repeat tRNA-synt_2b PF00587.20 KFH48083.1 - 4.2e-66 221.7 0.0 9.5e-66 220.6 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KFH48083.1 - 1e-22 79.8 0.4 6.5e-22 77.2 0.0 2.5 2 0 0 2 2 2 1 Anticodon binding domain G10 PF01125.12 KFH48085.1 - 4.9e-61 204.5 6.5 5.5e-61 204.3 4.5 1.0 1 0 0 1 1 1 1 G10 protein Methyltransf_21 PF05050.7 KFH48086.1 - 0.13 12.1 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase FkbM domain PTS_2-RNA PF01885.11 KFH48087.1 - 2.4e-63 212.7 0.0 3e-63 212.4 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family CSTF2_hinge PF14327.1 KFH48088.1 - 2.4e-29 101.2 1.3 4.1e-29 100.4 0.9 1.4 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 KFH48088.1 - 1.4e-21 75.8 0.0 2.3e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH48088.1 - 4.6e-16 58.5 0.0 8.4e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 KFH48088.1 - 1.3e-09 37.2 6.2 1.3e-09 37.2 4.3 2.8 3 0 0 3 3 3 1 Transcription termination and cleavage factor C-terminal RRM_5 PF13893.1 KFH48088.1 - 1.8e-09 37.2 0.0 2.6e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.1 KFH48088.1 - 0.069 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein family 7 Nucleoporin_FG PF13634.1 KFH48089.1 - 0.00072 19.7 30.6 0.00072 19.7 21.2 7.6 4 1 3 7 7 7 1 Nucleoporin FG repeat region WD40 PF00400.27 KFH48089.1 - 0.0067 16.2 0.1 0.031 14.1 0.1 2.3 1 0 0 1 1 1 1 WD domain, G-beta repeat Pkinase PF00069.20 KFH48091.1 - 3.3e-66 223.0 0.0 6.7e-66 222.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH48091.1 - 4.1e-36 124.3 0.0 6.9e-36 123.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH48091.1 - 8.1e-06 25.0 0.0 1.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFH48091.1 - 0.027 14.2 0.0 0.079 12.6 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KFH48091.1 - 0.068 11.9 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Apq12 PF12716.2 KFH48092.1 - 1.3e-05 24.7 18.6 3.4e-05 23.4 12.9 1.7 1 1 0 1 1 1 1 Nuclear pore assembly and biogenesis Abhydrolase_9_N PF15420.1 KFH48092.1 - 0.0055 16.4 6.3 0.0078 15.9 4.4 1.3 1 0 0 1 1 1 1 Alpha/beta-hydrolase family N-terminus PHD PF00628.24 KFH48094.1 - 1.5e-12 47.0 20.3 1.3e-08 34.3 7.2 2.8 2 1 1 3 3 3 2 PHD-finger C1_1 PF00130.17 KFH48094.1 - 0.0034 17.0 6.8 0.25 11.0 1.0 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.1 KFH48094.1 - 0.069 12.4 6.0 2.1 7.6 1.5 2.8 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.1 KFH48094.1 - 0.093 12.0 13.6 0.57 9.5 2.9 3.1 3 0 0 3 3 3 0 PHD-finger zf-HC5HC2H PF13771.1 KFH48094.1 - 0.1 12.7 5.2 0.25 11.5 0.9 2.3 2 0 0 2 2 2 0 PHD-like zinc-binding domain Prok-RING_1 PF14446.1 KFH48094.1 - 0.36 10.6 16.6 2.1 8.1 1.5 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 MPC PF03650.8 KFH48095.1 - 3.4e-33 114.1 0.0 4.2e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) adh_short PF00106.20 KFH48096.1 - 1.3e-23 83.6 0.7 1.7e-23 83.3 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH48096.1 - 3.4e-19 69.5 0.0 4.3e-19 69.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH48096.1 - 2.4e-11 43.6 0.1 3.5e-11 43.1 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFH48096.1 - 0.011 15.1 0.0 0.025 13.9 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KFH48096.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RNase_T PF00929.19 KFH48097.1 - 1.2e-24 87.4 0.0 1.4e-24 87.2 0.0 1.0 1 0 0 1 1 1 1 Exonuclease VRR_NUC PF08774.6 KFH48098.1 - 8.1e-17 61.0 0.0 3.1e-16 59.1 0.0 2.0 2 0 0 2 2 2 1 VRR-NUC domain THF_DHG_CYH PF00763.18 KFH48100.1 - 1.3e-19 70.3 0.1 1.9e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 KFH48100.1 - 1.9e-14 53.0 0.0 4.9e-09 35.4 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MTS PF05175.9 KFH48100.1 - 0.0072 15.7 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Shikimate_DH PF01488.15 KFH48100.1 - 0.046 13.8 0.2 27 4.8 0.0 3.5 4 1 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase TAP35_44 PF07265.6 KFH48101.1 - 0.031 14.0 0.2 0.067 12.9 0.2 1.5 1 0 0 1 1 1 0 Tapetum specific protein TAP35/TAP44 FAA_hydrolase PF01557.13 KFH48102.1 - 8.5e-55 185.5 0.0 1.1e-54 185.2 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family WD40 PF00400.27 KFH48103.1 - 4.6e-65 213.3 18.3 2.2e-13 49.4 0.0 7.7 7 1 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KFH48103.1 - 4.5e-09 36.3 0.0 5.9e-05 22.8 0.0 2.9 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KFH48103.1 - 1.2e-08 33.6 1.0 0.0021 16.2 0.1 3.0 2 2 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFH48103.1 - 4.1e-07 29.1 0.0 0.0031 16.3 0.0 3.5 2 1 1 4 4 4 2 Nup133 N terminal like DUF3312 PF11768.3 KFH48103.1 - 0.037 12.2 0.0 0.78 7.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3312) TPR_6 PF13174.1 KFH48104.1 - 0.089 13.2 0.1 9.2 6.9 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-FPG_IleRS PF06827.9 KFH48104.1 - 0.39 10.4 8.5 0.31 10.7 0.1 2.5 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-RING_2 PF13639.1 KFH48104.1 - 0.46 10.3 11.0 0.38 10.6 5.1 2.6 2 1 0 2 2 2 0 Ring finger domain Nol1_Nop2_Fmu PF01189.12 KFH48106.1 - 5e-16 58.9 0.0 2.4e-10 40.2 0.0 2.6 2 0 0 2 2 2 2 NOL1/NOP2/sun family Pkinase PF00069.20 KFH48107.1 - 2.1e-71 240.1 0.1 3.9e-71 239.2 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH48107.1 - 3.4e-53 180.3 0.1 6.6e-53 179.4 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 KFH48107.1 - 4.9e-22 78.1 0.7 1.4e-21 76.6 0.0 2.3 2 0 0 2 2 2 1 P21-Rho-binding domain PH_11 PF15413.1 KFH48107.1 - 2.9e-07 30.7 0.5 1.1e-06 28.8 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain Kinase-like PF14531.1 KFH48107.1 - 8e-07 28.2 0.0 1.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFH48107.1 - 0.0036 17.0 0.1 0.0036 17.0 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KFH48107.1 - 0.066 12.0 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DDRGK PF09756.4 KFH48107.1 - 0.69 9.2 13.6 1.9 7.8 9.4 1.7 1 0 0 1 1 1 0 DDRGK domain CENP-H PF05837.7 KFH48108.1 - 3e-24 85.2 4.2 3.9e-23 81.6 0.1 2.5 2 1 0 2 2 2 2 Centromere protein H (CENP-H) Microtub_assoc PF07989.6 KFH48108.1 - 0.78 9.6 4.5 1.3 8.9 0.2 2.8 2 2 1 3 3 3 0 Microtubule associated TMF_TATA_bd PF12325.3 KFH48108.1 - 3.9 7.2 9.6 3.7 7.2 1.7 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF972 PF06156.8 KFH48108.1 - 7 7.0 8.4 0.68 10.2 0.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF972) MFS_1 PF07690.11 KFH48109.1 - 1.1e-28 100.0 15.9 1.5e-28 99.5 11.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily His_Phos_2 PF00328.17 KFH48111.1 - 9.5e-08 31.7 0.0 1e-05 25.0 0.0 2.6 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Transgly_assoc PF04226.8 KFH48111.1 - 0.09 12.8 1.3 7 6.8 0.1 2.6 2 0 0 2 2 2 0 Transglycosylase associated protein Tubulin PF00091.20 KFH48112.1 - 8.9e-65 218.5 0.0 1.2e-64 218.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFH48112.1 - 1.9e-43 147.4 0.0 2.9e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KFH48112.1 - 0.00014 21.3 0.0 0.00025 20.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Zn_clus PF00172.13 KFH48113.1 - 1.8e-07 30.9 9.5 3.1e-07 30.1 6.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KCl_Cotrans_1 PF03522.10 KFH48114.1 - 0.028 13.9 1.7 0.073 12.5 0.5 2.1 2 0 0 2 2 2 0 K-Cl Co-transporter type 1 (KCC1) LURAP PF14854.1 KFH48114.1 - 0.065 12.9 0.8 0.21 11.3 0.1 2.0 2 0 0 2 2 2 0 Leucine rich adaptor protein Atg14 PF10186.4 KFH48114.1 - 0.089 11.7 1.3 0.12 11.3 0.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4140 PF13600.1 KFH48114.1 - 0.14 12.5 2.2 0.29 11.5 1.5 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) FSIP1 PF15554.1 KFH48114.1 - 0.21 10.3 4.7 0.37 9.5 3.2 1.4 1 0 0 1 1 1 0 FSIP1 family IncA PF04156.9 KFH48114.1 - 0.4 10.2 2.2 0.63 9.6 1.5 1.2 1 0 0 1 1 1 0 IncA protein zf-H2C2_2 PF13465.1 KFH48116.1 - 1.5e-10 40.8 17.0 1.2e-05 25.3 0.2 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 KFH48116.1 - 1.9e-08 34.1 20.9 1.8e-05 24.7 3.1 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.2 KFH48116.1 - 6.5e-06 26.1 1.5 1.8e-05 24.7 1.0 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFH48116.1 - 6.1e-05 23.0 5.1 0.00011 22.1 1.4 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KFH48116.1 - 6.7e-05 22.9 19.1 0.00019 21.5 1.6 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFH48116.1 - 0.0038 17.0 1.5 0.0038 17.0 1.1 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KFH48116.1 - 0.031 14.3 2.4 0.044 13.8 0.9 1.8 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 KFH48116.1 - 2.2 8.1 5.9 0.91 9.3 1.1 2.2 1 1 1 2 2 2 0 BED zinc finger Arginosuc_synth PF00764.14 KFH48117.1 - 7.8e-145 482.7 0.0 9e-145 482.5 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 KFH48117.1 - 0.019 14.2 0.0 0.038 13.2 0.0 1.5 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 KFH48117.1 - 0.054 12.0 0.1 0.14 10.7 0.0 1.6 1 0 0 1 1 1 0 tRNA methyl transferase TPR_3 PF07720.7 KFH48117.1 - 0.055 13.2 0.3 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Asn_synthase PF00733.16 KFH48117.1 - 0.094 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase TPR_11 PF13414.1 KFH48120.1 - 1.3e-32 111.2 33.9 1e-09 37.9 1.5 11.4 9 3 2 11 11 11 6 TPR repeat TPR_2 PF07719.12 KFH48120.1 - 1.8e-30 102.3 32.8 0.00022 20.8 0.1 13.0 13 0 0 13 13 11 9 Tetratricopeptide repeat TPR_1 PF00515.23 KFH48120.1 - 2.4e-30 102.8 30.3 8.2e-06 25.2 0.1 12.3 13 0 0 13 13 13 9 Tetratricopeptide repeat TPR_8 PF13181.1 KFH48120.1 - 1.6e-22 77.4 26.2 2.3e-05 23.8 0.1 12.7 13 1 0 13 13 13 5 Tetratricopeptide repeat TPR_12 PF13424.1 KFH48120.1 - 1.8e-22 79.0 29.4 4.3e-08 32.9 1.3 10.5 8 4 3 11 11 10 4 Tetratricopeptide repeat TPR_7 PF13176.1 KFH48120.1 - 1.8e-20 71.0 13.1 0.00011 21.7 0.0 11.2 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.1 KFH48120.1 - 7.9e-18 63.3 36.2 0.0027 18.2 0.0 13.4 12 3 4 16 16 13 5 Tetratricopeptide repeat TPR_19 PF14559.1 KFH48120.1 - 1.7e-16 60.3 37.8 0.0044 17.3 0.0 10.8 10 1 1 12 12 11 6 Tetratricopeptide repeat TPR_16 PF13432.1 KFH48120.1 - 5.3e-15 55.6 49.2 0.0023 18.5 0.5 12.6 13 3 0 13 13 11 5 Tetratricopeptide repeat TPR_6 PF13174.1 KFH48120.1 - 4.5e-11 42.4 23.5 0.015 15.7 0.0 11.3 13 0 0 13 13 10 4 Tetratricopeptide repeat Apc3 PF12895.2 KFH48120.1 - 2.1e-10 40.5 15.6 0.025 14.7 0.2 8.0 6 2 0 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 KFH48120.1 - 1.9e-09 36.9 17.1 1.5 9.2 0.1 11.4 12 1 0 12 12 11 1 Tetratricopeptide repeat TPR_10 PF13374.1 KFH48120.1 - 8e-07 28.7 17.8 2.1 8.3 0.0 9.0 9 1 1 10 10 10 3 Tetratricopeptide repeat PPR PF01535.15 KFH48120.1 - 0.024 14.5 0.3 5.9 7.1 0.0 4.2 3 0 0 3 3 2 0 PPR repeat NDUFA12 PF05071.11 KFH48121.1 - 2.2e-11 44.1 0.3 2.2e-11 44.1 0.2 2.3 1 1 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 FAD_binding_3 PF01494.14 KFH48122.1 - 7.6e-28 97.5 0.2 2.4e-26 92.6 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFH48122.1 - 8.8e-07 28.1 0.2 0.00048 19.1 0.1 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KFH48122.1 - 6.8e-05 21.9 0.2 0.0031 16.5 0.0 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein SE PF08491.5 KFH48122.1 - 0.0017 17.2 0.0 0.0027 16.6 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.9 KFH48122.1 - 0.0055 16.5 0.0 0.0098 15.7 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KFH48122.1 - 0.063 11.9 0.1 1.3 7.5 0.0 2.5 2 1 0 3 3 3 0 Tryptophan halogenase Thi4 PF01946.12 KFH48122.1 - 0.093 11.8 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family K_oxygenase PF13434.1 KFH48122.1 - 0.14 11.0 0.0 0.26 10.1 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) SNase PF00565.12 KFH48123.1 - 1.2e-24 86.6 0.1 1.8e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue LRR_6 PF13516.1 KFH48125.1 - 3.2e-12 45.1 0.1 0.0094 15.9 0.0 6.9 6 1 0 6 6 6 2 Leucine Rich repeat F-box-like PF12937.2 KFH48125.1 - 5.8e-12 45.1 0.3 1.7e-11 43.6 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFH48125.1 - 3.1e-09 36.2 0.1 1e-08 34.5 0.1 2.0 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.28 KFH48125.1 - 7.3e-09 34.4 1.9 0.22 11.6 0.0 7.0 7 2 1 8 8 8 2 Leucine Rich Repeat LRR_8 PF13855.1 KFH48125.1 - 5.3e-06 26.0 2.8 0.007 16.0 0.1 4.6 4 1 1 5 5 5 1 Leucine rich repeat LRR_4 PF12799.2 KFH48125.1 - 2.1e-05 24.0 5.8 1.7 8.3 0.1 5.7 3 2 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KFH48125.1 - 4.8e-05 22.8 6.2 1.8 9.0 0.1 6.8 7 0 0 7 7 7 1 Leucine rich repeat PRANC PF09372.5 KFH48125.1 - 0.034 14.1 0.1 0.15 12.0 0.0 2.1 2 0 0 2 2 2 0 PRANC domain DUF4533 PF15047.1 KFH48126.1 - 0.11 11.9 6.7 0.018 14.4 2.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4533) Filament PF00038.16 KFH48126.1 - 0.14 11.6 32.9 0.19 11.1 22.8 1.1 1 0 0 1 1 1 0 Intermediate filament protein 3-HAO PF06052.7 KFH48127.1 - 1.5e-61 206.2 0.0 1.7e-61 206.0 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 KFH48127.1 - 2.1e-06 27.0 0.0 3.3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 KFH48127.1 - 8.8e-05 21.9 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 KFH48127.1 - 0.0019 17.9 0.0 0.0029 17.3 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain ARD PF03079.9 KFH48127.1 - 0.036 14.0 0.0 0.055 13.4 0.0 1.2 1 0 0 1 1 1 0 ARD/ARD' family Cupin_6 PF12852.2 KFH48127.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.5 1 1 0 1 1 1 0 Cupin Cupin_4 PF08007.7 KFH48127.1 - 0.12 11.5 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Cupin superfamily protein DUF3133 PF11331.3 KFH48127.1 - 0.13 11.8 0.6 3.7 7.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) DZR PF12773.2 KFH48127.1 - 0.25 11.1 1.8 0.91 9.3 1.3 1.8 1 1 0 1 1 1 0 Double zinc ribbon SET PF00856.23 KFH48128.1 - 4.5e-08 33.5 0.2 0.002 18.4 0.1 3.3 3 1 0 3 3 3 2 SET domain TPR_11 PF13414.1 KFH48128.1 - 0.0026 17.3 0.7 3 7.5 0.4 2.4 2 0 0 2 2 2 2 TPR repeat DUF4111 PF13427.1 KFH48128.1 - 0.1 12.4 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) BTB_2 PF02214.17 KFH48129.1 - 8.5e-09 35.5 0.0 1.8e-08 34.4 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain Ribosomal_S13_N PF08069.7 KFH48130.1 - 3.7e-30 103.5 0.1 7.4e-30 102.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 KFH48130.1 - 6e-22 77.2 0.1 1.1e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 KFH48130.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 'Paired box' domain Fork_head PF00250.13 KFH48131.1 - 1.5e-32 111.4 0.1 2.7e-32 110.6 0.1 1.3 1 0 0 1 1 1 1 Fork head domain Amastin PF07344.6 KFH48132.1 - 0.00079 19.0 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF3040 PF11239.3 KFH48132.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Sds3 PF08598.6 KFH48133.1 - 1.4e-15 57.3 8.3 2.1e-15 56.8 5.1 4.4 2 1 0 3 3 3 2 Sds3-like WD40 PF00400.27 KFH48134.1 - 3.2e-74 242.3 22.9 1.1e-09 37.8 0.1 11.7 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp12 PF04003.7 KFH48134.1 - 1.1e-20 73.5 0.7 1.8e-20 72.9 0.5 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 KFH48134.1 - 0.00018 19.8 0.4 0.022 12.9 0.0 3.6 3 1 0 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFH48134.1 - 0.0081 14.9 7.6 13 4.3 0.1 5.7 3 2 0 5 5 5 2 Nup133 N terminal like eIF2A PF08662.6 KFH48134.1 - 0.02 14.6 0.2 1.2 8.8 0.0 3.8 2 1 2 4 4 4 0 Eukaryotic translation initiation factor eIF2A UTP15_C PF09384.5 KFH48134.1 - 0.025 14.2 1.2 0.073 12.7 0.2 2.0 2 0 0 2 2 2 0 UTP15 C terminal SNF5 PF04855.7 KFH48136.1 - 2e-75 253.4 0.3 2e-75 253.4 0.2 1.7 2 0 0 2 2 2 1 SNF5 / SMARCB1 / INI1 TolB_N PF04052.8 KFH48136.1 - 0.086 12.9 0.0 1.5 8.9 0.0 2.4 2 0 0 2 2 2 0 TolB amino-terminal domain Totivirus_coat PF05518.6 KFH48136.1 - 3.3 5.4 13.6 5.7 4.6 9.4 1.3 1 0 0 1 1 1 0 Totivirus coat protein OGG_N PF07934.7 KFH48137.1 - 4e-18 65.4 0.0 9.4e-18 64.2 0.0 1.6 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 KFH48137.1 - 1.4e-14 54.2 0.0 2.4e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KFH48137.1 - 0.00014 21.3 0.0 0.0003 20.3 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif Ycf1 PF05758.7 KFH48139.1 - 5 4.6 9.8 6.7 4.2 6.8 1.1 1 0 0 1 1 1 0 Ycf1 MaoC_dehydratas PF01575.14 KFH48142.1 - 2.4e-23 81.8 0.0 4.4e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 KFH48142.1 - 1.6e-09 37.6 0.0 5.6e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase DUF3246 PF11596.3 KFH48143.1 - 0.52 9.5 4.1 0.4 9.9 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3246) RNA_pol_L_2 PF13656.1 KFH48144.1 - 1e-30 104.9 0.0 1.3e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KFH48144.1 - 4.1e-10 38.6 0.0 5.6e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_Rpo13 PF12136.3 KFH48144.1 - 0.57 9.9 7.1 1.1 8.9 4.9 1.5 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain CBF PF03914.12 KFH48145.1 - 2.1e-47 160.6 0.7 6.4e-47 159.0 0.1 2.2 3 0 0 3 3 3 1 CBF/Mak21 family Pkinase PF00069.20 KFH48146.1 - 4.9e-58 196.3 0.0 8e-58 195.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH48146.1 - 4.8e-33 114.3 0.0 8.3e-32 110.2 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH48146.1 - 4.1e-07 29.2 0.0 8e-07 28.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFH48146.1 - 0.0066 16.2 5.9 0.0067 16.1 0.3 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFH48146.1 - 0.3 9.8 0.0 0.46 9.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Git3 PF11710.3 KFH48148.1 - 5.9e-18 65.1 4.5 5.9e-18 65.1 3.1 1.9 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 KFH48148.1 - 7.2e-12 44.9 12.1 1.8e-11 43.6 6.5 2.0 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.6 KFH48148.1 - 9.8e-07 27.9 9.2 1.6e-06 27.2 6.4 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor TIP41 PF04176.8 KFH48149.1 - 6.3e-73 243.8 0.1 8.1e-73 243.5 0.1 1.1 1 0 0 1 1 1 1 TIP41-like family DUF3446 PF11928.3 KFH48149.1 - 2.2 8.5 8.7 4.7 7.4 6.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) UAA PF08449.6 KFH48150.1 - 1.8e-71 240.5 2.5 6.5e-71 238.7 1.8 1.7 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KFH48150.1 - 3.6e-08 33.5 23.2 1.3e-06 28.4 3.2 3.4 3 0 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 KFH48150.1 - 3.5e-06 26.3 0.7 0.029 13.4 0.1 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 KFH48150.1 - 9.2e-05 22.6 5.2 9.2e-05 22.6 3.6 3.5 2 1 1 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 KFH48150.1 - 0.00091 18.9 3.9 0.00091 18.9 2.7 2.7 2 1 0 2 2 2 1 Triose-phosphate Transporter family LSM PF01423.17 KFH48151.1 - 5.9e-16 57.7 0.0 7.7e-16 57.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KFH48151.1 - 0.00058 19.7 0.0 0.00088 19.1 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF3247 PF11607.3 KFH48151.1 - 0.079 13.2 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3247) Nop14 PF04147.7 KFH48152.1 - 4.9 4.9 36.4 6.8 4.4 25.2 1.1 1 0 0 1 1 1 0 Nop14-like family PX PF00787.19 KFH48153.1 - 7.4e-19 67.6 0.0 3.2e-18 65.5 0.0 2.1 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 KFH48153.1 - 1.5e-14 53.8 7.1 1.9e-08 33.8 0.0 2.1 2 0 0 2 2 2 2 Vps5 C terminal like SET PF00856.23 KFH48154.1 - 3.1e-08 34.0 1.3 5.5e-08 33.2 0.9 1.6 1 0 0 1 1 1 1 SET domain DUF3915 PF13054.1 KFH48154.1 - 0.13 12.1 7.0 0.059 13.3 3.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) Pkinase PF00069.20 KFH48155.1 - 1.6e-62 211.0 0.0 2.2e-62 210.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH48155.1 - 1.2e-27 96.6 0.0 1.8e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH48155.1 - 0.0003 19.8 0.0 0.00049 19.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFH48155.1 - 0.017 14.8 0.3 1.2 8.7 0.0 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 KFH48155.1 - 0.027 13.5 0.0 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IER PF05760.7 KFH48155.1 - 8 6.2 16.5 13 5.6 11.4 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) zf-LYAR PF08790.6 KFH48156.1 - 2.1e-14 52.8 4.0 2.1e-14 52.8 2.7 1.8 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger DUF3810 PF12725.2 KFH48157.1 - 0.099 11.5 0.1 0.15 10.9 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) PSRT PF07636.6 KFH48158.1 - 0.014 14.8 0.4 0.014 14.8 0.3 1.8 2 0 0 2 2 2 0 PSRT BRE1 PF08647.6 KFH48159.1 - 7e-26 90.0 10.1 7e-26 90.0 7.0 6.4 4 2 1 5 5 4 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 KFH48159.1 - 6.1e-09 35.7 10.6 1e-08 35.0 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFH48159.1 - 1e-08 34.7 8.4 1.6e-08 34.0 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFH48159.1 - 4.3e-08 32.6 11.7 7.9e-08 31.8 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFH48159.1 - 1.9e-06 27.5 8.2 3.4e-06 26.7 5.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KFH48159.1 - 2.3e-06 27.2 10.7 3.9e-06 26.4 7.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KFH48159.1 - 0.00013 21.6 6.9 0.00031 20.3 4.8 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFH48159.1 - 0.005 16.6 7.7 0.0099 15.7 5.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DivIC PF04977.10 KFH48159.1 - 0.0052 16.2 2.4 0.0052 16.2 1.7 9.5 4 2 3 9 9 9 3 Septum formation initiator zf-RING_6 PF14835.1 KFH48159.1 - 0.0078 15.9 2.0 0.016 15.0 1.4 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Phage_GP20 PF06810.6 KFH48159.1 - 0.009 15.4 7.9 0.009 15.4 5.5 7.2 3 2 3 6 6 4 1 Phage minor structural protein GP20 Prok-RING_4 PF14447.1 KFH48159.1 - 0.0094 15.4 2.7 0.019 14.5 1.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.2 KFH48159.1 - 0.017 15.2 6.8 0.053 13.6 4.7 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger Bacillus_HBL PF05791.6 KFH48159.1 - 0.019 14.3 0.2 0.019 14.3 0.1 5.8 4 1 1 6 6 6 0 Bacillus haemolytic enterotoxin (HBL) zf-C2HC_2 PF13913.1 KFH48159.1 - 0.052 13.2 0.1 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Reo_sigmaC PF04582.7 KFH48159.1 - 0.16 11.1 29.9 0.086 12.0 3.7 4.1 3 1 2 5 5 5 0 Reovirus sigma C capsid protein zf-RING_4 PF14570.1 KFH48159.1 - 0.16 11.6 7.2 0.55 9.8 5.1 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 KFH48159.1 - 0.27 10.7 5.7 0.58 9.7 4.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C2H2_jaz PF12171.3 KFH48159.1 - 0.74 10.0 3.2 58 3.9 0.0 3.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding FYVE PF01363.16 KFH48159.1 - 1.4 8.8 11.1 13 5.7 7.8 2.3 1 1 0 1 1 1 0 FYVE zinc finger DZR PF12773.2 KFH48159.1 - 4.6 7.1 8.3 19 5.1 5.9 1.8 1 1 0 1 1 1 0 Double zinc ribbon DUF3584 PF12128.3 KFH48159.1 - 8.3 3.5 73.4 0.061 10.6 32.8 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF3584) RNA_pol_A_bac PF01000.21 KFH48160.1 - 1.2e-25 89.7 0.0 2.4e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KFH48160.1 - 2.3e-14 52.2 0.0 3.4e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain EXS PF03124.9 KFH48162.1 - 9.3e-102 340.5 4.8 1.1e-101 340.4 3.3 1.0 1 0 0 1 1 1 1 EXS family Complex1_LYR_2 PF13233.1 KFH48163.1 - 7e-07 29.6 0.1 8.2e-07 29.4 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.1 KFH48163.1 - 9.3e-06 25.7 0.4 1.5e-05 25.1 0.2 1.5 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KFH48163.1 - 2e-05 24.2 0.1 4e-05 23.3 0.1 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Telomere_reg-2 PF10193.4 KFH48164.1 - 3.9e-36 123.7 0.0 1.7e-35 121.7 0.0 2.2 2 0 0 2 2 2 1 Telomere length regulation protein Proteasome PF00227.21 KFH48166.1 - 4e-46 156.6 0.0 5.1e-46 156.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 KFH48166.1 - 3.5e-13 48.5 0.3 7.7e-13 47.4 0.2 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Pkinase PF00069.20 KFH48167.1 - 4.1e-54 183.4 0.0 5.8e-54 182.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH48167.1 - 8.7e-42 142.9 0.0 1.3e-41 142.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH48167.1 - 0.00014 20.9 0.0 0.00037 19.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KFH48167.1 - 0.012 15.3 0.8 0.19 11.4 0.1 2.9 2 1 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 KFH48167.1 - 0.03 13.3 0.0 0.065 12.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glucosamine_iso PF01182.15 KFH48168.1 - 6.4e-59 199.0 0.0 7.7e-59 198.7 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Peroxin-3 PF04882.7 KFH48169.1 - 4e-146 487.1 0.1 4.6e-146 486.9 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 PI-PLC-X PF00388.14 KFH48170.1 - 1e-12 47.7 0.0 1.5e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain GFO_IDH_MocA PF01408.17 KFH48172.1 - 6.3e-11 42.8 0.0 1.6e-10 41.5 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KFH48172.1 - 0.0002 21.1 0.0 0.00044 20.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain PUF PF00806.14 KFH48173.1 - 2.5e-19 67.6 0.1 0.00065 19.0 0.0 6.3 6 0 0 6 6 6 4 Pumilio-family RNA binding repeat RRM_1 PF00076.17 KFH48173.1 - 6.7e-14 51.2 0.0 1.4e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH48173.1 - 2e-07 30.7 0.0 3.6e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH48173.1 - 5.2e-07 29.5 0.0 1.4e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) COPIIcoated_ERV PF07970.7 KFH48175.1 - 5.6e-73 245.2 0.0 1.6e-71 240.5 0.0 2.3 2 1 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KFH48175.1 - 7.9e-35 118.7 0.0 3e-34 116.8 0.0 2.0 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) NUDIX PF00293.23 KFH48176.1 - 0.021 14.4 0.2 0.085 12.4 0.1 1.9 1 1 1 2 2 2 0 NUDIX domain dCMP_cyt_deam_1 PF00383.17 KFH48177.1 - 1.4e-15 56.7 0.0 1.9e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 KFH48177.1 - 1.4e-09 37.9 1.4 3.5e-09 36.7 0.1 1.9 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 KFH48177.1 - 0.00031 20.1 0.7 0.11 11.8 0.1 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Dicty_REP PF05086.7 KFH48178.1 - 7.4 4.1 19.1 0.13 9.9 7.9 1.7 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Acyl-CoA_dh_1 PF00441.19 KFH48179.1 - 3.1e-24 85.7 0.2 5.3e-24 85.0 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFH48179.1 - 1.4e-23 83.6 0.4 2.9e-23 82.5 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KFH48179.1 - 1e-15 56.9 0.0 2.4e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KFH48179.1 - 4.4e-08 33.4 0.2 8.1e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF1524 PF07510.6 KFH48180.1 - 8.9e-13 48.3 0.0 1e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) Drc1-Sld2 PF11719.3 KFH48181.1 - 2.5e-105 353.0 22.2 2.9e-105 352.8 15.4 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein DUF569 PF04601.8 KFH48181.1 - 0.011 15.2 0.1 0.029 13.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF569) FGE-sulfatase PF03781.11 KFH48182.1 - 5.9e-43 147.1 4.8 8e-43 146.6 3.3 1.2 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DUF1566 PF07603.6 KFH48182.1 - 0.06 13.0 3.0 0.14 11.9 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1566) COX6B PF02297.12 KFH48183.1 - 3.1e-20 71.9 4.5 3.9e-20 71.6 3.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb ATP_bind_3 PF01171.15 KFH48184.1 - 5.8e-43 146.5 0.0 2.1e-30 105.5 0.0 2.4 2 0 0 2 2 2 2 PP-loop family tRNA_Me_trans PF03054.11 KFH48184.1 - 0.079 11.5 0.0 0.3 9.5 0.0 1.7 2 0 0 2 2 2 0 tRNA methyl transferase Asp PF00026.18 KFH48185.1 - 1.8e-109 365.8 0.0 2.1e-109 365.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFH48185.1 - 4.1e-11 43.1 0.1 1.3e-10 41.4 0.0 1.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KFH48185.1 - 4.5e-07 29.5 0.0 1e-05 25.1 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KFH48185.1 - 3e-06 27.6 0.1 0.034 14.6 0.0 2.8 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.1 KFH48185.1 - 0.0034 17.1 0.4 2.9 7.7 0.0 3.2 3 1 1 4 4 4 2 gag-polyprotein putative aspartyl protease Alpha-amylase_C PF02806.13 KFH48185.1 - 0.065 13.3 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain tRNA-synt_2b PF00587.20 KFH48186.1 - 1.4e-24 86.6 0.0 2e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KFH48186.1 - 1.1e-08 35.0 0.9 1.9e-08 34.2 0.7 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain VHS PF00790.14 KFH48188.1 - 0.00012 21.7 0.0 0.00025 20.7 0.0 1.4 1 0 0 1 1 1 1 VHS domain CTD_bind PF04818.8 KFH48188.1 - 0.008 16.3 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. zf-C2H2_4 PF13894.1 KFH48188.1 - 0.16 12.3 5.0 7.6 7.1 0.5 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger RRN7 PF11781.3 KFH48188.1 - 0.77 9.3 3.9 0.65 9.5 0.5 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 DUF3337 PF11816.3 KFH48189.1 - 6.7e-91 305.1 0.0 7.3e-87 291.8 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.27 KFH48189.1 - 2.4e-26 90.5 6.7 4.1e-07 29.6 0.2 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 KFH48189.1 - 0.0074 14.4 1.0 0.031 12.4 0.0 2.3 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFH48189.1 - 0.0085 14.8 0.2 0.12 11.1 0.0 2.2 2 0 0 2 2 2 1 Nup133 N terminal like Apc1 PF12859.2 KFH48190.1 - 9.5e-25 86.8 0.9 2.7e-24 85.4 0.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 KFH48190.1 - 4.2e-05 23.5 2.2 0.038 14.2 0.1 4.5 5 0 0 5 5 5 2 Proteasome/cyclosome repeat Glyco_hydro_38C PF07748.8 KFH48190.1 - 0.2 10.4 0.0 0.31 9.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal domain tRNA-synt_2 PF00152.15 KFH48191.1 - 4e-66 223.0 0.0 7.4e-66 222.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KFH48191.1 - 3.2e-09 36.4 0.0 5.5e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Sec23_trunk PF04811.10 KFH48193.1 - 1.4e-52 178.4 0.0 3.3e-52 177.2 0.0 1.6 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KFH48193.1 - 8.9e-24 82.9 0.0 1.5e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KFH48193.1 - 1.1e-17 64.3 0.0 1.9e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KFH48193.1 - 5.2e-17 61.1 5.9 1.1e-16 60.0 4.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KFH48193.1 - 5.4e-07 29.2 0.0 1.2e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Gon7 PF08738.5 KFH48194.1 - 4.9e-16 58.5 2.3 6.3e-15 55.0 1.6 2.0 1 1 0 1 1 1 1 Gon7 family GatB_N PF02934.10 KFH48195.1 - 7.5e-101 336.8 0.0 9.6e-101 336.4 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 KFH48195.1 - 7.3e-14 51.7 0.0 4.6e-13 49.1 0.0 2.1 2 0 0 2 2 2 1 GatB domain FRQ PF09421.5 KFH48196.1 - 0 1276.1 52.3 0 1275.8 36.3 1.0 1 0 0 1 1 1 1 Frequency clock protein MscS_porin PF12795.2 KFH48196.1 - 0.11 11.7 0.6 0.2 10.9 0.4 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain EBP PF05241.7 KFH48197.1 - 2.5e-61 206.0 10.2 3.2e-61 205.7 7.0 1.0 1 0 0 1 1 1 1 Emopamil binding protein UQ_con PF00179.21 KFH48199.1 - 2.8e-49 166.1 0.0 3.1e-49 165.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFH48199.1 - 5.7e-05 22.8 0.0 6.5e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFH48199.1 - 0.005 16.7 0.0 0.006 16.4 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KFH48199.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain DUF917 PF06032.7 KFH48200.1 - 1.2e-110 369.4 0.5 1.6e-110 368.9 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 KFH48200.1 - 2.7e-49 167.8 0.1 1e-47 162.6 0.0 2.6 2 1 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KFH48200.1 - 1.1e-27 96.6 0.1 5.7e-25 87.8 0.0 3.0 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region BcrAD_BadFG PF01869.15 KFH48200.1 - 1.3e-05 24.6 0.1 0.00021 20.6 0.0 2.6 3 0 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family MutL PF13941.1 KFH48200.1 - 0.00024 19.5 0.4 0.036 12.3 0.0 2.3 2 0 0 2 2 2 2 MutL protein StbA PF06406.6 KFH48200.1 - 0.025 13.5 0.2 1.4 7.8 0.1 2.3 2 0 0 2 2 2 0 StbA protein RAP1 PF07218.6 KFH48202.1 - 0.28 9.2 1.3 0.25 9.3 0.9 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) LIM_bind PF01803.11 KFH48203.1 - 1.1e-75 253.8 0.0 1.1e-75 253.8 0.0 3.8 2 1 1 4 4 4 1 LIM-domain binding protein SPX PF03105.14 KFH48204.1 - 4.7e-44 151.2 0.0 1.2e-43 149.8 0.0 1.7 1 1 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 KFH48204.1 - 8.8e-33 113.8 35.2 5.8e-32 111.1 24.4 1.9 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 KFH48204.1 - 1.5e-13 50.1 37.8 5.3e-13 48.2 15.6 2.6 2 1 1 3 3 3 2 Citrate transporter DUF3702 PF12486.3 KFH48204.1 - 0.054 13.1 0.5 0.1 12.2 0.4 1.3 1 0 0 1 1 1 0 ImpA domain protein SMN PF06003.7 KFH48205.1 - 7.7e-09 35.0 7.4 5.3e-07 29.0 1.1 2.2 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) eIF3_N PF09440.5 KFH48206.1 - 2.5e-21 76.2 5.8 4.9e-17 62.3 4.0 2.7 1 1 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 KFH48206.1 - 4e-14 52.8 0.0 1.5e-13 50.9 0.0 2.0 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 KFH48206.1 - 0.0085 15.8 0.1 0.019 14.7 0.1 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 XhlA PF10779.4 KFH48206.1 - 0.97 9.3 0.0 0.97 9.3 0.0 2.9 2 1 0 2 2 2 0 Haemolysin XhlA U3_assoc_6 PF08640.6 KFH48207.1 - 3.9e-25 87.4 0.5 3.2e-24 84.4 0.1 2.5 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.5 KFH48207.1 - 0.0002 20.3 3.0 0.00022 20.1 0.6 2.0 1 1 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 KFH48207.1 - 0.0024 18.3 0.0 2.9 8.7 0.0 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat DHC_N1 PF08385.7 KFH48207.1 - 0.05 11.9 0.1 0.085 11.2 0.0 1.2 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 TPR_11 PF13414.1 KFH48207.1 - 0.13 11.9 0.0 2.6 7.7 0.0 2.4 2 0 0 2 2 2 0 TPR repeat HAD_2 PF13419.1 KFH48208.1 - 3.4e-21 76.2 0.0 5.3e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase FHA PF00498.21 KFH48208.1 - 2.7e-13 49.8 0.0 4.7e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 FHA domain Hydrolase_like PF13242.1 KFH48208.1 - 0.024 14.3 0.1 0.068 12.8 0.0 1.8 1 0 0 1 1 1 0 HAD-hyrolase-like MIP-T3 PF10243.4 KFH48208.1 - 0.034 12.6 28.3 0.044 12.2 19.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 MFS_1 PF07690.11 KFH48209.1 - 3.7e-20 71.9 58.8 4.6e-18 65.0 38.3 3.1 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFH48209.1 - 2.2e-05 22.9 25.8 3.5e-05 22.2 17.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FAM165 PF14981.1 KFH48209.1 - 0.028 13.9 2.1 0.21 11.1 0.0 2.5 2 0 0 2 2 2 0 FAM165 family DNA_pol_A_exo1 PF01612.15 KFH48210.1 - 1.1e-40 139.0 0.0 1.6e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 KFH48210.1 - 5.9e-25 87.3 0.5 1.6e-24 86.0 0.3 1.8 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.18 KFH48210.1 - 2.9e-12 46.1 0.0 6.4e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 HRDC domain Ndc1_Nup PF09531.5 KFH48210.1 - 7.4 4.8 4.7 1.1e+02 0.9 0.0 2.0 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup GRAB PF10375.4 KFH48211.1 - 3e-09 36.1 0.2 6.4e-09 35.0 0.1 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain WEMBL PF05701.6 KFH48211.1 - 0.00018 20.1 28.0 0.00018 20.1 19.4 2.6 2 1 1 3 3 3 1 Weak chloroplast movement under blue light Tup_N PF08581.5 KFH48211.1 - 0.0028 17.8 1.3 0.0028 17.8 0.9 4.8 2 1 3 5 5 5 1 Tup N-terminal Rootletin PF15035.1 KFH48211.1 - 0.0044 17.0 15.0 0.0044 17.0 10.4 3.9 1 1 1 3 3 3 2 Ciliary rootlet component, centrosome cohesion Dak2 PF02734.12 KFH48211.1 - 0.089 12.4 3.0 0.29 10.8 2.1 2.0 1 0 0 1 1 1 0 DAK2 domain FlxA PF14282.1 KFH48211.1 - 0.15 12.0 0.2 0.15 12.0 0.1 6.2 3 2 3 6 6 4 0 FlxA-like protein Baculo_PEP_C PF04513.7 KFH48211.1 - 0.58 9.9 18.4 0.25 11.1 1.7 3.2 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.16 KFH48211.1 - 1.2 8.5 57.6 2.3 7.6 22.5 2.3 1 1 1 2 2 2 0 Intermediate filament protein Reo_sigmaC PF04582.7 KFH48211.1 - 1.2 8.2 15.3 1 8.4 1.7 3.1 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Laminin_II PF06009.7 KFH48211.1 - 1.6 8.4 31.1 0.77 9.5 4.1 4.3 1 1 2 4 4 4 0 Laminin Domain II NPV_P10 PF05531.7 KFH48211.1 - 3 8.1 18.1 0.6 10.4 2.4 4.2 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1212 PF06738.7 KFH48211.1 - 6.5 6.1 6.3 14 5.0 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1212) Spc7 PF08317.6 KFH48211.1 - 7.3 5.1 47.7 0.1 11.2 12.9 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein IncA PF04156.9 KFH48211.1 - 9.4 5.7 62.1 29 4.1 13.7 3.5 1 1 1 2 2 1 0 IncA protein CHD5 PF04420.9 KFH48212.1 - 9e-51 171.7 1.6 6.9e-25 87.5 0.1 2.3 2 0 0 2 2 2 2 CHD5-like protein KH_1 PF00013.24 KFH48213.1 - 5.9e-44 147.5 11.6 1.8e-15 56.3 0.7 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KFH48213.1 - 6.9e-33 111.7 17.0 7.4e-12 44.6 1.3 3.9 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 KFH48213.1 - 1.6e-13 49.9 1.7 0.0044 16.5 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KFH48213.1 - 6.4e-08 32.1 3.8 0.22 11.1 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 KFH48213.1 - 4.2e-05 23.2 4.3 0.046 13.5 0.0 3.5 4 0 0 4 4 4 2 NusA-like KH domain Sugar_tr PF00083.19 KFH48214.1 - 2.1e-89 300.2 26.6 2.6e-89 299.8 18.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH48214.1 - 7.2e-16 57.8 47.1 9.7e-11 40.9 13.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Frag1 PF10277.4 KFH48215.1 - 7.1e-41 140.0 9.3 7.1e-41 140.0 6.5 2.8 2 0 0 2 2 2 2 Frag1/DRAM/Sfk1 family Img2 PF05046.9 KFH48216.1 - 5.3e-17 61.8 0.0 7.1e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Gag_spuma PF03276.9 KFH48216.1 - 3.7 5.7 7.6 8.3 4.5 5.1 1.6 2 0 0 2 2 2 0 Spumavirus gag protein zf-RING_2 PF13639.1 KFH48217.1 - 4 7.3 6.7 25 4.7 0.2 2.2 1 1 1 2 2 2 0 Ring finger domain DUF4050 PF13259.1 KFH48219.1 - 2e-30 105.2 0.1 4.2e-30 104.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) RAP1 PF07218.6 KFH48219.1 - 0.16 10.0 3.5 0.21 9.6 2.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NAD_binding_6 PF08030.7 KFH48223.1 - 3.9e-31 108.0 0.0 6.4e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KFH48223.1 - 5.3e-22 77.6 0.2 3.6e-21 74.9 0.0 2.4 3 1 0 3 3 3 1 FAD-binding domain Ferric_reduct PF01794.14 KFH48223.1 - 2.2e-17 63.2 9.1 2.2e-17 63.2 6.3 2.3 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KFH48223.1 - 0.006 16.6 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KFH48223.1 - 0.054 14.0 0.0 0.64 10.6 0.0 2.5 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF2562 PF10814.3 KFH48224.1 - 0.058 13.3 0.9 1.5 8.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2562) Mis14 PF08641.7 KFH48225.1 - 7.2e-08 32.5 0.8 9.2e-08 32.2 0.1 1.6 2 0 0 2 2 2 1 Kinetochore protein Mis14 like Rpn3_C PF08375.6 KFH48226.1 - 1.2e-25 89.6 1.4 3.9e-25 88.0 0.9 1.9 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 KFH48226.1 - 1.2e-20 73.7 0.3 1.7e-19 70.0 0.0 2.6 3 0 0 3 3 3 1 PCI domain TPR_2 PF07719.12 KFH48226.1 - 0.0057 16.4 0.1 0.02 14.7 0.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat FMO-like PF00743.14 KFH48227.1 - 2.5e-30 105.1 0.0 2.4e-24 85.4 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KFH48227.1 - 7.3e-18 65.3 0.0 3.4e-17 63.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFH48227.1 - 4.1e-10 39.0 0.0 1.4e-08 34.0 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KFH48227.1 - 6e-08 32.8 0.0 1.4e-06 28.3 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFH48227.1 - 2.4e-07 30.6 0.1 1.9e-05 24.4 0.1 2.5 1 1 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KFH48227.1 - 0.0082 15.2 0.2 1.1 8.2 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KFH48227.1 - 0.023 14.7 0.0 0.12 12.4 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF2325 PF10087.4 KFH48227.1 - 0.12 12.2 0.0 0.52 10.1 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) adh_short PF00106.20 KFH48228.1 - 1.3e-25 90.2 0.2 2.8e-25 89.1 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFH48228.1 - 6.3e-09 35.9 0.0 1.4e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFH48228.1 - 3.5e-08 33.3 0.0 2.9e-07 30.3 0.0 2.2 2 0 0 2 2 2 1 KR domain Methyltransf_26 PF13659.1 KFH48228.1 - 0.00052 20.0 0.0 0.00084 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Pyr_redox_3 PF13738.1 KFH48228.1 - 0.026 14.5 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 KFH48229.1 - 6.5e-38 130.3 43.6 6.5e-38 130.3 30.2 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH48229.1 - 1e-07 30.9 23.9 4.7e-07 28.7 16.7 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter PBP1_TM PF14812.1 KFH48230.1 - 0.0093 16.2 5.9 0.0093 16.2 4.1 2.9 2 1 1 3 3 3 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Sporozoite_P67 PF05642.6 KFH48230.1 - 0.2 9.4 7.7 0.33 8.7 5.3 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cwf_Cwc_15 PF04889.7 KFH48230.1 - 4 7.0 19.8 0.38 10.4 7.6 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.7 KFH48230.1 - 6.3 5.9 13.5 0.36 10.0 5.6 1.7 2 0 0 2 2 2 0 NOA36 protein Glyco_hydro_16 PF00722.16 KFH48231.1 - 9.9e-13 47.7 0.1 1.3e-12 47.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Asp PF00026.18 KFH48232.1 - 1.1e-62 212.1 1.0 1.3e-62 211.8 0.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFH48232.1 - 3.5e-08 33.5 0.3 1.4e-07 31.5 0.0 2.1 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KFH48232.1 - 0.0014 19.0 0.0 0.083 13.3 0.0 3.0 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.1 KFH48232.1 - 0.011 15.3 0.0 0.021 14.3 0.0 1.6 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Pneumo_att_G PF05539.6 KFH48232.1 - 3.4 6.9 6.8 6.5 6.0 4.7 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Fungal_trans_2 PF11951.3 KFH48233.1 - 3.4e-35 121.3 0.8 3.7e-34 117.9 0.5 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH48233.1 - 1e-08 34.9 12.0 1.9e-08 34.0 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.14 KFH48233.1 - 0.054 13.1 4.6 0.2 11.4 3.2 2.1 1 0 0 1 1 1 0 AT hook motif MFS_1 PF07690.11 KFH48235.1 - 4.2e-32 111.2 68.1 2.3e-28 98.9 22.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KFH48235.1 - 0.001 18.8 6.4 0.0094 15.7 0.3 3.6 5 0 0 5 5 5 2 MFS_1 like family DNA_methylase PF00145.12 KFH48237.1 - 5.3e-33 114.5 0.0 1.5e-32 113.0 0.0 1.7 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 KFH48237.1 - 1.9e-06 27.6 0.2 0.07 12.8 0.0 2.9 4 0 0 4 4 4 2 BAH domain DNMT1-RFD PF12047.3 KFH48237.1 - 0.0078 15.9 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain Fungal_trans PF04082.13 KFH48238.1 - 3.8e-06 25.9 0.0 8.8e-06 24.7 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain YlbE PF14003.1 KFH48238.1 - 0.055 13.5 0.1 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 YlbE-like protein TEP1_N PF05386.6 KFH48238.1 - 1.7 8.1 4.5 8.3 5.9 0.7 2.7 2 0 0 2 2 2 0 TEP1 N-terminal domain AIP3 PF03915.8 KFH48239.1 - 6e-157 522.9 6.9 8.4e-157 522.4 4.8 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 Lectin_N PF03954.9 KFH48239.1 - 0.0086 15.4 0.7 0.036 13.4 0.1 2.4 2 0 0 2 2 2 1 Hepatic lectin, N-terminal domain FliL PF03748.9 KFH48239.1 - 0.016 15.2 0.0 0.084 12.8 0.0 2.3 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL Syntaxin_2 PF14523.1 KFH48239.1 - 0.041 13.9 8.3 1.1 9.3 0.0 4.5 4 1 0 4 4 4 0 Syntaxin-like protein DUF1664 PF07889.7 KFH48239.1 - 0.098 12.4 10.0 0.31 10.8 0.1 4.2 3 1 0 4 4 4 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 KFH48239.1 - 0.17 12.1 0.1 0.17 12.1 0.1 3.8 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein COMP PF11598.3 KFH48239.1 - 0.19 11.8 2.3 26 5.0 0.0 3.4 3 0 0 3 3 3 0 Cartilage oligomeric matrix protein DUF3138 PF11336.3 KFH48239.1 - 0.19 9.8 0.2 0.32 9.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Glyco_hydro_61 PF03443.9 KFH48240.1 - 4e-47 160.8 0.0 4.8e-47 160.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ATP-synt_C PF00137.16 KFH48241.1 - 2e-16 59.6 10.9 3.2e-16 58.9 7.6 1.3 1 0 0 1 1 1 1 ATP synthase subunit C adh_short PF00106.20 KFH48242.1 - 2.5e-17 63.2 0.6 3.9e-17 62.6 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH48242.1 - 1.9e-07 30.9 0.1 3.1e-07 30.2 0.1 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFH48242.1 - 0.036 14.0 0.1 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding DUF1289 PF06945.8 KFH48244.1 - 0.23 10.9 1.5 0.33 10.4 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) Pkinase PF00069.20 KFH48245.1 - 1.1e-39 136.1 0.0 1.7e-39 135.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH48245.1 - 3.4e-21 75.4 0.0 4.5e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KFH48245.1 - 1.4e-06 28.3 0.1 2.6e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 KFH48245.1 - 0.013 14.4 0.0 0.077 11.9 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Peptidase_M43 PF05572.8 KFH48246.1 - 1.3e-12 47.5 0.0 2.3e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.1 KFH48246.1 - 0.00027 21.0 0.2 0.00063 19.8 0.2 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KFH48246.1 - 0.00082 19.3 0.0 0.002 18.0 0.0 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.19 KFH48246.1 - 0.0011 18.7 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Matrixin Reprolysin_4 PF13583.1 KFH48246.1 - 0.0085 15.6 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KFH48246.1 - 0.06 13.8 0.3 0.16 12.5 0.0 2.0 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Prenylcys_lyase PF07156.9 KFH48247.1 - 9.7e-31 106.9 0.0 1.8e-30 106.0 0.0 1.3 1 1 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 KFH48247.1 - 3.8e-12 46.0 0.0 9.1e-12 44.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KFH48247.1 - 3.3e-10 39.6 0.0 1.1e-09 37.9 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.19 KFH48247.1 - 1.9e-05 23.7 0.4 5.4e-05 22.2 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KFH48247.1 - 2.3e-05 24.2 0.5 0.00019 21.2 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KFH48247.1 - 0.00012 22.0 0.8 0.023 14.5 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFH48247.1 - 0.00086 19.4 0.2 0.003 17.6 0.0 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFH48247.1 - 0.0062 15.6 0.3 0.014 14.5 0.1 1.6 2 0 0 2 2 2 1 Thi4 family Shikimate_DH PF01488.15 KFH48247.1 - 0.037 14.1 0.0 0.073 13.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 KFH48247.1 - 0.041 12.7 0.5 0.076 11.8 0.4 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KFH48247.1 - 0.093 11.1 0.2 0.14 10.5 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 KFH48247.1 - 0.11 11.2 0.6 0.18 10.6 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF883 PF05957.8 KFH48248.1 - 0.00041 20.6 9.4 0.015 15.6 0.5 2.7 1 1 2 3 3 3 2 Bacterial protein of unknown function (DUF883) CsbD PF05532.7 KFH48248.1 - 0.043 13.4 37.3 48 3.7 7.0 5.0 1 1 1 2 2 2 0 CsbD-like DUF3659 PF12396.3 KFH48248.1 - 0.86 9.3 5.1 2.5 7.8 2.6 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3659) DivIVA PF05103.8 KFH48248.1 - 1.3 9.1 7.9 13 5.8 0.1 2.3 2 0 0 2 2 2 0 DivIVA protein YtxH PF12732.2 KFH48248.1 - 1.3 9.4 13.2 1.2e+03 -0.1 9.1 3.0 1 1 0 1 1 1 0 YtxH-like protein ApoLp-III PF07464.6 KFH48248.1 - 1.7 8.6 8.7 1.1 9.2 1.0 2.3 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) BMFP PF04380.8 KFH48248.1 - 1.8 8.7 4.2 7.6 6.7 0.3 3.2 1 1 2 3 3 3 0 Membrane fusogenic activity zf-H2C2_2 PF13465.1 KFH48250.1 - 7.1e-06 26.0 4.0 7.1e-06 26.0 2.8 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 KFH48250.1 - 5e-05 23.4 12.1 0.018 15.3 1.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFH48250.1 - 0.004 17.3 2.2 0.004 17.3 1.5 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger DUF4407 PF14362.1 KFH48250.1 - 0.59 9.0 4.3 1.2 7.9 3.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DSBA PF01323.15 KFH48251.1 - 1.2e-37 129.3 0.0 1.4e-37 129.1 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.1 KFH48251.1 - 0.00018 21.2 0.0 0.015 15.0 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_4 PF13462.1 KFH48251.1 - 0.00022 21.2 0.0 0.00035 20.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin DUF1525 PF07511.6 KFH48251.1 - 0.0014 18.5 0.2 0.0026 17.7 0.0 1.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1525) Thioredoxin_5 PF13743.1 KFH48251.1 - 0.043 13.3 0.0 0.067 12.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DUF3984 PF13136.1 KFH48252.1 - 5.8e-73 245.9 10.0 5.8e-73 245.9 6.9 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3984) Nucleoplasmin PF03066.10 KFH48252.1 - 0.094 12.2 8.6 0.044 13.2 3.0 2.1 2 0 0 2 2 2 0 Nucleoplasmin DUF2263 PF10021.4 KFH48253.1 - 1e-11 45.0 0.0 1.5e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Med9 PF07544.8 KFH48254.1 - 1.5e-18 66.2 2.2 3.4e-18 65.1 1.5 1.7 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 DUF4618 PF15397.1 KFH48254.1 - 0.094 12.0 0.1 0.11 11.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Myb_DNA-bind_6 PF13921.1 KFH48256.1 - 1.3e-15 57.1 6.3 5.4e-09 36.0 0.3 3.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KFH48256.1 - 3.2e-13 49.4 9.3 6.5e-08 32.5 0.0 4.7 4 1 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 KFH48256.1 - 0.0003 20.8 2.8 0.0016 18.5 2.0 2.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain SYS1 PF09801.4 KFH48257.1 - 2.2e-46 157.4 3.2 2.5e-46 157.2 2.2 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network TrbE PF11100.3 KFH48257.1 - 0.15 11.9 2.1 0.24 11.3 0.8 1.8 1 1 1 2 2 2 0 Conjugal transfer protein TrbE Phage_holin_5 PF06946.6 KFH48257.1 - 0.47 10.6 3.2 1 9.5 2.2 1.5 1 0 0 1 1 1 0 Phage holin Folliculin PF11704.3 KFH48258.1 - 5e-29 101.0 0.0 1.5e-28 99.5 0.0 1.8 1 1 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport zf-C2H2_3 PF13878.1 KFH48259.1 - 0.055 13.0 0.0 0.14 11.7 0.0 1.8 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO YL1 PF05764.8 KFH48259.1 - 5.1 6.6 14.7 0.2 11.2 6.0 1.7 2 0 0 2 2 2 0 YL1 nuclear protein Axin_b-cat_bind PF08833.5 KFH48261.1 - 0.27 10.9 2.6 17 5.2 0.0 2.6 2 1 1 3 3 3 0 Axin beta-catenin binding domain p450 PF00067.17 KFH48262.1 - 7.6e-12 44.4 0.0 2.1e-10 39.7 0.0 2.6 1 1 0 1 1 1 1 Cytochrome P450 Asp PF00026.18 KFH48263.1 - 7e-36 124.0 0.0 1e-35 123.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KFH48263.1 - 1.1e-05 25.8 0.0 0.0063 16.9 0.0 3.1 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KFH48263.1 - 1.8e-05 24.3 0.1 0.12 11.9 0.0 2.8 3 0 0 3 3 3 2 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 KFH48263.1 - 0.064 13.0 0.0 0.22 11.3 0.0 2.0 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF1744 PF08490.7 KFH48264.1 - 9.3e-146 485.4 0.0 1.3e-145 484.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 KFH48264.1 - 3.4e-61 206.8 0.2 6.3e-61 206.0 0.2 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 KFH48264.1 - 1.6e-22 79.9 0.1 3.9e-22 78.6 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 KFH48264.1 - 2.8e-09 36.8 0.1 7.5e-09 35.4 0.1 1.7 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 KFH48264.1 - 1e-05 25.4 0.0 3.8e-05 23.5 0.0 2.1 1 0 0 1 1 1 1 RNase_H superfamily DNA_pol3_alpha PF07733.7 KFH48264.1 - 0.0086 14.5 0.0 0.018 13.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha subunit LRV_FeS PF05484.6 KFH48264.1 - 0.39 10.3 7.5 0.087 12.4 2.2 2.2 2 0 0 2 2 2 0 LRV protein FeS4 cluster MFS_1 PF07690.11 KFH48265.1 - 2.4e-33 115.3 24.0 2.4e-33 115.3 16.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Cupin_1 PF00190.17 KFH48267.1 - 7.9e-08 31.8 0.0 1.3e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 KFH48267.1 - 0.0049 16.3 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 Cupin domain Glyco_hydro_47 PF01532.15 KFH48268.1 - 3.9e-169 563.0 0.0 5.9e-169 562.4 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 AAA PF00004.24 KFH48269.1 - 2e-45 154.1 0.7 5.4e-45 152.8 0.0 2.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFH48269.1 - 4.4e-09 36.1 0.4 1.6e-08 34.3 0.1 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KFH48269.1 - 5.5e-08 32.9 0.0 1.2e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KFH48269.1 - 5.6e-07 29.7 0.0 1.8e-06 28.0 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFH48269.1 - 2.6e-06 27.6 2.0 0.0003 20.9 0.5 2.7 2 1 0 2 2 1 1 AAA domain DUF815 PF05673.8 KFH48269.1 - 4.3e-06 25.8 0.0 9.4e-06 24.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 KFH48269.1 - 0.00021 21.2 0.0 0.00076 19.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KFH48269.1 - 0.00037 19.6 0.0 0.00083 18.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KFH48269.1 - 0.00052 20.0 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KFH48269.1 - 0.00064 19.8 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase UPF0079 PF02367.12 KFH48269.1 - 0.00096 18.7 0.1 0.041 13.5 0.0 2.3 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 KFH48269.1 - 0.0011 18.7 0.1 0.056 13.0 0.0 2.9 3 0 0 3 3 2 1 NACHT domain AAA_17 PF13207.1 KFH48269.1 - 0.0013 19.5 0.0 0.0051 17.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KFH48269.1 - 0.0014 18.3 0.2 0.0034 17.1 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 KFH48269.1 - 0.002 16.9 0.0 0.0037 16.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus NTPase_1 PF03266.10 KFH48269.1 - 0.0022 17.7 0.0 0.0083 15.8 0.0 2.0 2 0 0 2 2 2 1 NTPase Zeta_toxin PF06414.7 KFH48269.1 - 0.0037 16.3 0.0 0.012 14.7 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_3 PF07726.6 KFH48269.1 - 0.0041 16.7 0.0 0.013 15.0 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KFH48269.1 - 0.0042 16.9 0.0 0.011 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 KFH48269.1 - 0.0044 17.3 0.3 0.93 9.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KFH48269.1 - 0.0053 16.3 0.8 0.016 14.8 0.0 2.0 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KFH48269.1 - 0.0056 16.4 0.2 0.081 12.6 0.0 2.5 2 1 1 3 3 3 1 Archaeal ATPase AAA_25 PF13481.1 KFH48269.1 - 0.0059 16.0 0.7 0.073 12.4 0.1 2.4 1 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KFH48269.1 - 0.0068 15.5 0.0 0.016 14.3 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 KFH48269.1 - 0.011 15.2 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KFH48269.1 - 0.011 15.2 0.1 0.028 14.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KFH48269.1 - 0.012 15.0 0.6 0.031 13.6 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.1 KFH48269.1 - 0.017 15.4 0.0 0.052 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KFH48269.1 - 0.031 13.3 1.5 0.46 9.5 0.0 2.6 3 0 0 3 3 3 0 KaiC Bac_DnaA PF00308.13 KFH48269.1 - 0.032 13.8 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein Sigma54_activat PF00158.21 KFH48269.1 - 0.047 13.1 0.0 1.5 8.2 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 KFH48269.1 - 0.12 12.4 0.1 0.51 10.3 0.0 2.2 2 1 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 KFH48269.1 - 0.17 10.7 0.0 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Acetyltransf_8 PF13523.1 KFH48271.1 - 3.3e-43 147.1 0.6 5.1e-43 146.5 0.4 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KFH48271.1 - 0.074 13.2 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CRAL_TRIO PF00650.15 KFH48272.1 - 2.4e-35 121.3 0.0 3.8e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KFH48272.1 - 9.6e-09 35.2 0.4 3.3e-08 33.5 0.2 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KFH48272.1 - 0.00083 19.2 0.0 0.0033 17.3 0.0 1.9 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Herpes_U59 PF04529.7 KFH48272.1 - 0.097 11.4 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus U59 protein Peroxidase_2 PF01328.12 KFH48274.1 - 6.7e-34 116.9 0.0 8.1e-34 116.7 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Mito_carr PF00153.22 KFH48275.1 - 2.7e-65 216.1 12.1 1.2e-25 89.0 0.1 4.0 4 0 0 4 4 4 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 KFH48275.1 - 6.7e-20 70.9 1.1 5.4e-13 48.8 0.6 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 KFH48275.1 - 6e-17 59.5 2.5 6.9e-05 21.8 0.2 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 KFH48275.1 - 2.4e-14 51.8 2.6 7.7e-06 25.3 0.2 3.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 KFH48275.1 - 7.1e-12 44.1 5.6 0.00054 19.1 0.3 3.7 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 KFH48275.1 - 1e-07 31.4 2.6 2.1e-05 24.0 0.1 2.8 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFH48275.1 - 2e-06 27.7 0.1 3.2e-05 23.9 0.0 2.2 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region XPG_N PF00752.12 KFH48276.1 - 1.8e-31 108.3 0.0 3.9e-31 107.2 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 KFH48276.1 - 2.8e-31 107.4 0.0 4.8e-31 106.6 0.0 1.4 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 KFH48276.1 - 1.2e-06 28.6 0.0 5e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.2 KFH48276.1 - 0.026 14.4 0.0 0.086 12.7 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif TniB PF05621.6 KFH48276.1 - 0.11 11.2 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein CPSF100_C PF13299.1 KFH48278.1 - 2.3e-39 135.1 0.0 5.3e-39 133.9 0.0 1.6 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 KFH48278.1 - 8.3e-26 90.3 0.1 6.6e-25 87.4 0.0 2.5 4 0 0 4 4 4 1 Beta-Casp domain RMMBL PF07521.7 KFH48278.1 - 1.5e-06 27.8 0.0 3.2e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lact_bio_phlase PF09508.5 KFH48278.1 - 0.12 10.0 0.1 1.3 6.6 0.0 2.0 1 1 1 2 2 2 0 Lacto-N-biose phosphorylase Lactamase_B PF00753.22 KFH48278.1 - 0.12 12.0 0.0 1 8.9 0.0 2.2 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Aldose_epim PF01263.15 KFH48279.1 - 2.1e-55 187.9 0.0 2.9e-55 187.5 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase WSC PF01822.14 KFH48280.1 - 3.6e-11 42.8 6.8 6.6e-11 41.9 4.7 1.5 1 0 0 1 1 1 1 WSC domain DUF4366 PF14283.1 KFH48280.1 - 0.00036 20.0 0.4 0.00076 18.9 0.2 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4366) DUF4448 PF14610.1 KFH48280.1 - 0.002 17.6 0.0 0.0028 17.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) SKG6 PF08693.5 KFH48280.1 - 0.0036 16.5 0.3 0.0071 15.6 0.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MEA1 PF06910.6 KFH48280.1 - 0.018 14.7 2.9 3.4 7.3 0.0 2.7 2 1 1 3 3 3 0 Male enhanced antigen 1 (MEA1) DUF3530 PF12048.3 KFH48280.1 - 0.02 13.9 0.8 0.025 13.5 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Herpes_gE PF02480.11 KFH48280.1 - 0.054 11.7 0.0 0.074 11.3 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E PIP5K PF01504.13 KFH48281.1 - 5.1e-86 287.8 0.1 8e-86 287.2 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase AKAP7_NLS PF10469.4 KFH48282.1 - 2.5e-31 109.0 0.0 3.6e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.1 KFH48282.1 - 0.00039 20.1 0.1 0.001 18.7 0.0 1.6 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.11 KFH48282.1 - 0.045 13.7 0.1 8.4 6.4 0.0 2.4 2 0 0 2 2 2 0 LigT like Phosphoesterase Cutinase PF01083.17 KFH48283.1 - 2.6e-49 167.3 0.0 3.1e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Cutinase VirJ PF06057.6 KFH48283.1 - 0.00084 19.1 0.0 0.0012 18.7 0.0 1.1 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.6 KFH48283.1 - 0.012 15.0 0.1 0.017 14.5 0.1 1.2 1 0 0 1 1 1 0 PE-PPE domain CorA PF01544.13 KFH48284.1 - 0.16 10.9 0.1 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Glyco_hydro_16 PF00722.16 KFH48285.1 - 3.2e-26 91.7 0.2 4.4e-26 91.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 UPF0203 PF05254.7 KFH48286.1 - 2.3e-27 94.6 2.0 2.7e-27 94.3 1.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 KFH48286.1 - 0.0016 18.2 5.0 0.022 14.5 0.2 2.3 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.8 KFH48286.1 - 0.011 15.7 1.8 0.027 14.4 1.3 1.6 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) UCR_hinge PF02320.11 KFH48286.1 - 0.037 13.9 2.0 1.2 9.0 0.1 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein COX6B PF02297.12 KFH48286.1 - 2.6 8.1 7.0 2.7 8.0 0.5 1.7 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb HpaP PF09483.5 KFH48287.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 Type III secretion protein (HpaP) SRR1 PF07985.7 KFH48287.1 - 0.014 15.3 0.0 0.033 14.1 0.0 1.7 1 1 0 1 1 1 0 SRR1 NeuB PF03102.9 KFH48287.1 - 0.045 12.8 0.0 0.078 12.1 0.0 1.3 1 0 0 1 1 1 0 NeuB family DUF566 PF04484.7 KFH48288.1 - 0.36 10.2 4.3 0.5 9.8 3.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) YebG PF07130.7 KFH48289.1 - 0.031 13.9 1.7 0.045 13.4 0.1 2.0 2 0 0 2 2 2 0 YebG protein Ank_2 PF12796.2 KFH48290.1 - 7.1e-19 67.9 0.0 0.00026 21.2 0.1 6.9 2 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KFH48290.1 - 6.5e-14 50.9 1.4 0.12 12.2 0.0 8.1 9 0 0 9 9 9 3 Ankyrin repeat Ank_5 PF13857.1 KFH48290.1 - 1e-08 35.1 3.8 4.7 7.6 0.0 8.1 9 0 0 9 9 9 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFH48290.1 - 1.3e-08 34.2 1.4 4.3 7.8 0.0 8.1 9 0 0 9 9 9 2 Ankyrin repeat Ank_4 PF13637.1 KFH48290.1 - 4.6e-08 33.3 7.1 0.03 14.8 0.0 6.5 5 1 3 8 8 8 2 Ankyrin repeats (many copies) F-box-like PF12937.2 KFH48290.1 - 0.0097 15.6 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFH48290.1 - 0.021 14.4 0.3 0.041 13.5 0.2 1.5 1 0 0 1 1 1 0 F-box domain Spore_GerQ PF09671.5 KFH48290.1 - 0.036 13.6 0.1 0.071 12.7 0.1 1.4 1 0 0 1 1 1 0 Spore coat protein (Spore_GerQ) TFIID_20kDa PF03847.8 KFH48291.1 - 3.4e-18 65.6 0.2 7.5e-18 64.5 0.0 1.7 2 0 0 2 2 2 1 Transcription initiation factor TFIID subunit A LMBR1 PF04791.11 KFH48291.1 - 0.19 10.2 3.3 0.34 9.4 2.0 1.8 1 1 0 1 1 1 0 LMBR1-like membrane protein HbrB PF08539.6 KFH48292.1 - 4.5e-52 176.0 0.0 6.5e-52 175.5 0.0 1.2 1 0 0 1 1 1 1 HbrB-like Hpt PF01627.18 KFH48293.1 - 3.3e-13 49.4 0.0 4.8e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Hpt domain Choline_kin_N PF04428.9 KFH48293.1 - 0.091 12.2 0.0 2.8 7.4 0.0 2.4 2 1 0 2 2 2 0 Choline kinase N terminus MgsA_C PF12002.3 KFH48294.1 - 3.2e-60 202.6 0.0 6.6e-60 201.6 0.0 1.5 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 KFH48294.1 - 3.8e-14 53.0 0.1 7.4e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KFH48294.1 - 4.5e-11 42.2 0.0 1.6e-10 40.4 0.0 1.8 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 KFH48294.1 - 7.6e-06 25.5 0.0 0.00048 19.6 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 KFH48294.1 - 1e-05 25.2 0.1 7.4e-05 22.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KFH48294.1 - 2.5e-05 24.1 0.0 4.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KFH48294.1 - 5.7e-05 23.2 0.3 0.00035 20.6 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFH48294.1 - 5.8e-05 23.1 1.6 0.023 14.7 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain TIP49 PF06068.8 KFH48294.1 - 6.4e-05 21.8 0.0 0.00094 17.9 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus Mg_chelatase PF01078.16 KFH48294.1 - 8.2e-05 21.8 0.1 0.19 10.8 0.0 2.4 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KFH48294.1 - 0.00066 19.3 0.3 0.0021 17.7 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain DUF815 PF05673.8 KFH48294.1 - 0.00078 18.4 0.0 0.0012 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DNA_pol3_delta2 PF13177.1 KFH48294.1 - 0.0018 17.9 0.0 0.24 11.0 0.0 2.5 2 1 1 3 3 2 1 DNA polymerase III, delta subunit AAA_3 PF07726.6 KFH48294.1 - 0.0036 16.8 0.0 0.011 15.2 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CPT PF07931.7 KFH48294.1 - 0.005 16.4 0.0 0.0086 15.7 0.0 1.3 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.1 KFH48294.1 - 0.0065 17.2 0.0 0.018 15.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KFH48294.1 - 0.012 15.5 0.2 2.7 7.7 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.1 KFH48294.1 - 0.023 15.0 0.0 0.04 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain SKI PF01202.17 KFH48294.1 - 0.041 13.7 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase AAA_2 PF07724.9 KFH48294.1 - 0.043 13.7 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.1 KFH48294.1 - 0.048 13.6 0.5 0.12 12.3 0.4 1.7 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 KFH48294.1 - 0.055 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 KFH48294.1 - 0.057 13.1 0.1 3.5 7.2 0.0 2.5 1 1 1 2 2 2 0 Archaeal ATPase zf-C2HC_2 PF13913.1 KFH48294.1 - 0.097 12.3 1.3 0.2 11.3 0.1 2.1 2 0 0 2 2 2 0 zinc-finger of a C2HC-type AAA_23 PF13476.1 KFH48294.1 - 0.11 12.7 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain zf-TRAF PF02176.13 KFH48294.1 - 0.12 12.8 0.4 0.22 11.9 0.3 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger PIF1 PF05970.9 KFH48294.1 - 0.25 10.2 0.1 0.4 9.5 0.1 1.2 1 0 0 1 1 1 0 PIF1-like helicase Fungal_trans PF04082.13 KFH48295.1 - 2e-15 56.4 0.1 3e-15 55.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH48295.1 - 9.4e-05 22.2 15.0 0.00018 21.3 10.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clathrin PF00637.15 KFH48296.1 - 3.9e-19 68.6 1.9 3.1e-18 65.7 1.0 2.5 2 1 0 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.27 KFH48296.1 - 4.5e-06 26.3 0.6 0.0079 16.0 0.4 3.8 3 1 0 3 3 3 1 WD domain, G-beta repeat zf-RING_2 PF13639.1 KFH48296.1 - 0.00048 19.9 0.3 0.0011 18.6 0.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KFH48296.1 - 0.0021 17.7 1.6 0.0047 16.6 1.1 1.6 1 1 0 1 1 1 1 zinc-RING finger domain Vps39_1 PF10366.4 KFH48296.1 - 0.011 15.7 2.2 1.1 9.3 0.7 2.6 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 KFH48296.1 - 0.076 13.2 0.1 0.32 11.1 0.1 2.0 1 1 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 TPR_7 PF13176.1 KFH48296.1 - 0.09 12.6 0.3 0.74 9.7 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat BUD22 PF09073.5 KFH48296.1 - 0.15 11.1 23.5 0.0058 15.7 10.5 2.2 2 0 0 2 2 2 0 BUD22 DnaJ PF00226.26 KFH48297.1 - 4.4e-07 29.5 0.2 7.9e-07 28.7 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain DUF2613 PF11021.3 KFH48298.1 - 0.097 12.3 0.1 0.27 10.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) SNARE PF05739.14 KFH48299.1 - 0.072 12.7 0.2 10 5.8 0.0 2.3 2 0 0 2 2 2 0 SNARE domain polyprenyl_synt PF00348.12 KFH48300.1 - 4.4e-54 183.0 0.0 8.6e-51 172.2 0.0 2.3 2 0 0 2 2 2 2 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 KFH48300.1 - 0.032 13.6 0.0 0.059 12.8 0.0 1.4 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Ferric_reduct PF01794.14 KFH48301.1 - 2.1e-20 73.0 14.8 5e-20 71.8 10.2 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KFH48301.1 - 1.5e-08 34.4 0.0 0.00042 20.1 0.0 2.3 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.7 KFH48301.1 - 1.1e-06 28.6 0.2 0.039 13.8 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 KFH48301.1 - 0.18 12.3 0.0 0.44 11.1 0.0 1.7 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain ECH PF00378.15 KFH48302.1 - 1.9e-47 161.4 0.1 1e-44 152.5 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family ABC_membrane PF00664.18 KFH48303.1 - 2.4e-80 269.8 32.0 6.8e-47 160.1 5.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFH48303.1 - 1.5e-63 213.1 0.0 1.6e-31 109.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KFH48303.1 - 7e-14 52.4 0.0 0.00031 20.7 0.0 4.1 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 KFH48303.1 - 9e-14 51.2 2.2 0.00028 20.1 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KFH48303.1 - 5.4e-09 35.4 0.8 0.0031 16.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KFH48303.1 - 1.6e-08 35.4 0.0 0.0011 19.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 KFH48303.1 - 8.4e-06 25.4 0.4 0.02 14.4 0.0 4.2 4 1 0 4 4 4 1 AAA domain AAA_22 PF13401.1 KFH48303.1 - 1.2e-05 25.4 1.4 1.2 9.3 0.0 4.3 4 1 0 4 4 3 2 AAA domain AAA PF00004.24 KFH48303.1 - 2e-05 24.7 0.0 1.8 8.7 0.0 4.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KFH48303.1 - 3.7e-05 23.2 0.1 0.2 11.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 KFH48303.1 - 4.3e-05 22.7 0.0 0.064 12.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 KFH48303.1 - 4.3e-05 22.6 0.0 0.22 10.5 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_16 PF13191.1 KFH48303.1 - 6.7e-05 22.9 5.9 0.06 13.3 0.1 2.9 2 2 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.4 KFH48303.1 - 8.4e-05 21.3 0.4 0.019 13.5 0.0 2.7 3 0 0 3 3 3 1 Predicted ATPase of the ABC class SbcCD_C PF13558.1 KFH48303.1 - 0.00011 22.0 0.5 0.59 10.0 0.1 3.6 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit APS_kinase PF01583.15 KFH48303.1 - 0.0004 20.0 0.2 0.061 12.9 0.0 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_33 PF13671.1 KFH48303.1 - 0.00064 19.6 0.1 0.47 10.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KFH48303.1 - 0.0018 18.5 0.0 1.2 9.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KFH48303.1 - 0.0057 16.3 0.2 6.3 6.5 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 KFH48303.1 - 0.0057 16.9 0.0 3 8.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 KFH48303.1 - 0.0066 16.2 1.3 0.59 9.8 0.1 2.6 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_14 PF13173.1 KFH48303.1 - 0.01 15.7 0.0 1.6 8.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain ATP-synt_ab PF00006.20 KFH48303.1 - 0.016 14.6 0.0 2.4 7.6 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain G-alpha PF00503.15 KFH48303.1 - 0.053 12.2 0.0 2.5 6.6 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_10 PF12846.2 KFH48303.1 - 0.082 12.3 5.8 2.6 7.3 0.2 3.3 3 0 0 3 3 3 0 AAA-like domain DUF4102 PF13356.1 KFH48303.1 - 0.089 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4102) NB-ARC PF00931.17 KFH48303.1 - 0.094 11.5 0.2 8.5 5.1 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain MMR_HSR1 PF01926.18 KFH48303.1 - 0.2 11.6 1.6 13 5.7 0.0 3.2 3 0 0 3 3 3 0 50S ribosome-binding GTPase Glyco_transf_20 PF00982.16 KFH48304.1 - 3.3e-194 645.7 0.0 3.8e-194 645.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 KFH48304.1 - 0.032 13.7 0.2 0.085 12.3 0.1 1.7 2 0 0 2 2 2 0 Starch synthase catalytic domain SLT_2 PF13406.1 KFH48304.1 - 0.083 11.7 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Transglycosylase SLT domain Claudin_2 PF13903.1 KFH48305.1 - 0.00029 20.5 7.0 0.0059 16.3 4.9 2.1 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction Arif-1 PF06770.6 KFH48305.1 - 0.088 12.1 0.5 0.14 11.4 0.4 1.3 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) Neurensin PF14927.1 KFH48305.1 - 0.68 9.3 2.2 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Neurensin NfeD PF01957.13 KFH48305.1 - 9.4 6.3 7.8 4.6 7.3 0.0 2.7 1 1 2 3 3 3 0 NfeD-like C-terminal, partner-binding Amidohydro_1 PF01979.15 KFH48307.1 - 3.9e-17 62.9 1.2 5.2e-10 39.5 0.0 3.1 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 KFH48307.1 - 8.7e-14 52.1 6.4 1.1e-11 45.3 4.4 2.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KFH48307.1 - 8.6e-10 38.3 0.0 1.9e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KFH48307.1 - 3.1e-07 29.9 1.7 0.00017 20.9 0.4 2.6 2 1 0 2 2 2 2 Amidohydrolase family Aldo_ket_red PF00248.16 KFH48308.1 - 1.6e-52 178.1 0.0 2.4e-52 177.5 0.0 1.2 1 1 0 1 1 1 1 Aldo/keto reductase family Death PF00531.17 KFH48308.1 - 0.0003 20.4 0.0 0.17 11.6 0.0 3.1 2 1 1 3 3 3 2 Death domain Vps39_1 PF10366.4 KFH48310.1 - 3.9e-35 120.1 0.1 6.6e-34 116.1 0.0 3.0 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 KFH48310.1 - 2.3e-27 95.3 0.0 6.5e-27 93.8 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 KFH48310.1 - 4.9e-19 68.8 0.0 1e-18 67.7 0.0 1.6 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.15 KFH48310.1 - 4.2e-05 23.1 2.8 0.0011 18.6 0.3 3.2 3 0 0 3 3 3 1 Region in Clathrin and VPS Apc3 PF12895.2 KFH48310.1 - 0.0031 17.6 3.4 3.7 7.7 0.0 4.1 3 2 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 KFH48310.1 - 0.0035 17.9 0.2 5.8 7.7 0.0 4.3 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFH48310.1 - 0.0065 16.3 2.3 3.1 7.8 0.1 4.8 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFH48310.1 - 0.049 13.2 2.8 38 4.0 0.0 4.9 4 1 1 5 5 5 0 TPR repeat TPR_1 PF00515.23 KFH48310.1 - 0.051 13.1 6.6 0.97 9.1 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3893 PF13032.1 KFH48310.1 - 0.053 13.6 0.1 1 9.4 0.0 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF3893) TPR_2 PF07719.12 KFH48310.1 - 0.59 10.1 4.2 51 4.1 0.1 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat Actin PF00022.14 KFH48311.1 - 1.9e-23 82.5 0.0 1.3e-22 79.8 0.0 2.1 2 1 0 2 2 2 1 Actin MreB_Mbl PF06723.8 KFH48311.1 - 0.14 10.7 0.0 1.9 7.0 0.0 2.0 2 0 0 2 2 2 0 MreB/Mbl protein UCH PF00443.24 KFH48312.1 - 4.1e-39 134.3 0.0 9.1e-39 133.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFH48312.1 - 1.3e-15 57.6 0.0 7.5e-07 28.8 0.0 3.2 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 KFH48312.1 - 3.4e-05 23.1 0.0 0.033 13.5 0.0 2.9 2 0 0 2 2 2 2 A repeated domain in UCH-protein Fungal_trans PF04082.13 KFH48313.1 - 1.1e-06 27.7 0.0 1.6e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_4 PF01565.18 KFH48316.1 - 2.6e-21 75.5 1.3 4.7e-21 74.7 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFH48316.1 - 0.00085 19.1 0.1 0.0021 17.9 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like Cyclin_N PF00134.18 KFH48317.1 - 4.4e-13 48.9 0.3 9.9e-13 47.7 0.2 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Phage_int_SAM_4 PF13495.1 KFH48317.1 - 0.049 13.9 0.1 0.15 12.3 0.0 1.9 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Turandot PF07240.6 KFH48317.1 - 0.1 12.0 0.1 0.22 11.0 0.1 1.5 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot TFIIB PF00382.14 KFH48317.1 - 1.2 8.9 3.9 1.3 8.8 0.1 2.4 2 0 0 2 2 2 0 Transcription factor TFIIB repeat VSP PF03302.8 KFH48318.1 - 9.7e-05 21.1 2.3 0.00019 20.1 1.6 1.4 1 0 0 1 1 1 1 Giardia variant-specific surface protein Herpes_gE PF02480.11 KFH48318.1 - 0.0036 15.6 0.0 0.02 13.1 0.0 2.1 2 1 0 2 2 2 1 Alphaherpesvirus glycoprotein E UPF0060 PF02694.10 KFH48318.1 - 0.037 14.0 0.2 0.066 13.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised BCR, YnfA/UPF0060 family SKG6 PF08693.5 KFH48318.1 - 0.94 8.8 3.7 0.57 9.5 0.2 2.6 2 0 0 2 2 2 0 Transmembrane alpha-helix domain C2 PF00168.25 KFH48320.1 - 3e-21 75.0 0.0 3e-14 52.6 0.0 2.5 2 0 0 2 2 2 2 C2 domain PPTA PF01239.17 KFH48321.1 - 0.00025 20.2 13.3 0.035 13.4 0.1 4.1 4 0 0 4 4 4 2 Protein prenyltransferase alpha subunit repeat Mito_carr PF00153.22 KFH48323.1 - 4.9e-49 164.0 8.8 8.3e-18 63.8 0.2 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein CfAFP PF05264.6 KFH48324.1 - 2.3 7.9 8.8 8.6 6.1 0.2 2.1 1 1 1 2 2 2 0 Choristoneura fumiferana antifreeze protein (CfAFP) Ank_2 PF12796.2 KFH48326.1 - 1.8e-23 82.7 2.9 2.1e-12 47.2 0.8 2.8 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFH48326.1 - 1.5e-20 71.9 7.9 3.7e-07 29.6 0.1 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 KFH48326.1 - 2.7e-16 59.5 3.7 6.9e-08 32.8 0.3 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFH48326.1 - 3.7e-16 58.7 9.7 3.9e-06 26.9 0.4 4.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFH48326.1 - 4.7e-15 54.1 3.7 0.00036 20.5 0.1 4.7 5 0 0 5 5 5 3 Ankyrin repeat Acyl-CoA_dh_1 PF00441.19 KFH48327.1 - 2.4e-41 141.3 0.2 3.4e-41 140.8 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFH48327.1 - 6.6e-21 73.5 0.3 1.1e-20 72.8 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KFH48327.1 - 7.5e-21 74.8 0.0 1.8e-20 73.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.23 KFH48327.1 - 6.5e-19 67.5 0.3 1.1e-18 66.7 0.2 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.6 KFH48327.1 - 7.1e-08 32.7 0.0 1.2e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain FAD_binding_3 PF01494.14 KFH48328.1 - 1.8e-28 99.6 0.4 3.5e-17 62.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KFH48328.1 - 1.4e-07 31.3 0.1 6.7e-06 26.0 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KFH48328.1 - 2.8e-07 29.7 0.1 0.011 14.7 0.0 2.8 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.19 KFH48328.1 - 3.1e-06 26.3 0.2 0.0062 15.4 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KFH48328.1 - 3.9e-05 22.9 0.1 0.032 13.2 0.1 2.4 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 KFH48328.1 - 4.1e-05 23.7 0.0 0.0001 22.4 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFH48328.1 - 5.5e-05 23.4 0.1 0.12 12.7 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KFH48328.1 - 0.00018 20.2 0.5 0.034 12.7 0.0 2.8 2 1 1 3 3 3 1 Tryptophan halogenase HI0933_like PF03486.9 KFH48328.1 - 0.00058 18.4 0.0 0.023 13.1 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 KFH48328.1 - 0.00074 19.4 0.1 0.0013 18.6 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFH48328.1 - 0.001 17.9 0.1 0.0022 16.9 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 KFH48328.1 - 0.0018 18.0 0.4 0.05 13.3 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding SE PF08491.5 KFH48328.1 - 0.002 16.9 0.0 0.038 12.8 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase adh_short_C2 PF13561.1 KFH48330.1 - 4e-29 102.0 0.0 4.7e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFH48330.1 - 1.4e-25 90.1 0.3 2.6e-25 89.2 0.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KFH48330.1 - 3e-06 27.0 0.0 5.1e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFH48330.1 - 0.0012 18.2 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KFH48330.1 - 0.022 14.5 0.1 0.051 13.3 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Sugar_tr PF00083.19 KFH48331.1 - 3.5e-103 345.6 26.5 4.5e-103 345.2 18.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH48331.1 - 1.6e-24 86.3 44.0 3.8e-24 85.0 21.1 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Erythrovirus_X PF06795.6 KFH48331.1 - 0.6 10.1 3.2 0.46 10.5 0.6 2.0 2 0 0 2 2 2 0 Erythrovirus X protein Gpi1 PF05024.10 KFH48332.1 - 1.2e-63 214.2 4.3 2.1e-63 213.4 3.0 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) 7tm_1 PF00001.16 KFH48332.1 - 0.0038 16.3 0.3 0.0089 15.1 0.2 1.6 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Glyoxalase_2 PF12681.2 KFH48333.1 - 1.5e-06 28.7 0.0 1.9e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KFH48333.1 - 0.00027 20.9 0.1 0.0015 18.5 0.1 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily XPG_I PF00867.13 KFH48334.1 - 2e-25 88.6 0.0 4.6e-25 87.5 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KFH48334.1 - 9.9e-07 28.9 0.0 2.4e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain DUF4214 PF13946.1 KFH48334.1 - 0.1 12.2 0.1 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4214) DUF4452 PF14618.1 KFH48336.1 - 3.6e-71 238.3 15.5 4.2e-71 238.0 10.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) AAA PF00004.24 KFH48338.1 - 8.5e-32 110.1 0.0 9.3e-14 51.7 0.0 3.5 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFH48338.1 - 1.1e-12 48.2 5.4 0.068 13.3 0.0 6.2 3 3 0 3 3 3 3 AAA domain AAA_17 PF13207.1 KFH48338.1 - 3.3e-12 47.2 4.8 0.00051 20.8 0.2 4.5 3 2 0 3 3 3 3 AAA domain AAA_5 PF07728.9 KFH48338.1 - 5.3e-11 42.4 0.9 0.015 14.9 0.0 5.0 3 3 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KFH48338.1 - 5.5e-09 35.6 0.8 0.069 12.9 0.0 4.1 3 0 0 3 3 3 2 Part of AAA domain AAA_18 PF13238.1 KFH48338.1 - 7.7e-07 29.4 2.3 0.79 10.0 0.0 4.4 4 0 0 4 4 3 2 AAA domain AAA_16 PF13191.1 KFH48338.1 - 8.6e-07 29.1 1.1 0.94 9.4 0.0 5.3 3 2 1 5 5 5 1 AAA ATPase domain AAA_33 PF13671.1 KFH48338.1 - 8.8e-07 28.9 0.0 0.67 9.8 0.0 3.6 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.17 KFH48338.1 - 2.8e-06 27.4 0.0 2.6 8.2 0.0 3.7 3 0 0 3 3 3 1 RNA helicase AAA_30 PF13604.1 KFH48338.1 - 3.7e-06 26.6 3.8 1 8.9 0.0 4.9 3 2 0 3 3 3 1 AAA domain AAA_28 PF13521.1 KFH48338.1 - 4.7e-06 26.6 1.1 0.92 9.4 0.0 3.9 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.16 KFH48338.1 - 8.5e-06 25.0 0.1 0.45 9.6 0.0 3.5 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 KFH48338.1 - 1.3e-05 24.4 0.3 3.9 6.4 0.0 4.3 3 1 0 3 3 3 0 Holliday junction DNA helicase ruvB N-terminus Sigma54_activ_2 PF14532.1 KFH48338.1 - 4.9e-05 23.4 0.0 0.31 11.0 0.0 3.9 3 2 0 3 3 3 1 Sigma-54 interaction domain AAA_24 PF13479.1 KFH48338.1 - 6.6e-05 22.5 2.6 1.2 8.6 0.0 3.5 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.21 KFH48338.1 - 8.3e-05 22.1 0.2 0.33 10.4 0.0 4.0 4 1 0 4 4 3 1 Sigma-54 interaction domain AAA_14 PF13173.1 KFH48338.1 - 0.00037 20.3 0.0 3.6 7.4 0.0 3.6 3 0 0 3 3 3 0 AAA domain MobB PF03205.9 KFH48338.1 - 0.001 18.7 1.0 1.5 8.5 0.0 3.5 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 KFH48338.1 - 0.0012 18.2 0.1 9.7 5.5 0.0 3.6 3 0 0 3 3 3 0 IstB-like ATP binding protein VirE PF05272.6 KFH48338.1 - 0.0013 18.2 0.0 0.064 12.7 0.0 2.6 2 0 0 2 2 2 1 Virulence-associated protein E Torsin PF06309.6 KFH48338.1 - 0.0014 18.5 0.0 14 5.5 0.0 3.4 3 0 0 3 3 3 0 Torsin AAA_29 PF13555.1 KFH48338.1 - 0.0017 17.8 0.0 0.44 10.0 0.0 3.3 3 0 0 3 3 3 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KFH48338.1 - 0.0021 18.3 0.1 2.9 8.2 0.0 3.6 3 0 0 3 3 3 1 ABC transporter KTI12 PF08433.5 KFH48338.1 - 0.0024 17.1 0.0 10 5.2 0.0 3.6 3 0 0 3 3 3 0 Chromatin associated protein KTI12 AAA_25 PF13481.1 KFH48338.1 - 0.0025 17.2 0.1 14 5.0 0.0 4.3 4 0 0 4 4 4 0 AAA domain AAA_10 PF12846.2 KFH48338.1 - 0.0026 17.2 0.3 26 4.1 0.0 4.3 3 1 1 4 4 4 0 AAA-like domain Viral_helicase1 PF01443.13 KFH48338.1 - 0.0037 16.8 0.0 2.8 7.3 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 KFH48338.1 - 0.0047 16.5 0.1 0.95 8.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain Thymidylate_kin PF02223.12 KFH48338.1 - 0.012 15.0 0.4 1.3 8.3 0.0 3.2 3 0 0 3 3 3 0 Thymidylate kinase NTPase_1 PF03266.10 KFH48338.1 - 0.014 15.1 1.8 8.8 6.0 0.0 3.4 3 0 0 3 3 3 0 NTPase DUF815 PF05673.8 KFH48338.1 - 0.016 14.1 0.0 4.7 6.0 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF815) APS_kinase PF01583.15 KFH48338.1 - 0.016 14.8 0.0 3 7.4 0.0 3.4 3 0 0 3 3 3 0 Adenylylsulphate kinase Zeta_toxin PF06414.7 KFH48338.1 - 0.029 13.4 0.0 7.5 5.5 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin PGM_PMM_II PF02879.11 KFH48338.1 - 0.03 14.6 0.1 3.4 8.0 0.0 3.6 3 0 0 3 3 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PRK PF00485.13 KFH48338.1 - 0.031 13.8 0.0 5.1 6.6 0.0 3.2 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family PhoH PF02562.11 KFH48338.1 - 0.032 13.4 0.1 30 3.7 0.0 3.3 3 0 0 3 3 3 0 PhoH-like protein ArgK PF03308.11 KFH48338.1 - 0.049 12.4 0.2 11 4.7 0.0 2.9 3 0 0 3 3 3 0 ArgK protein G-alpha PF00503.15 KFH48338.1 - 0.08 11.6 0.1 0.36 9.4 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit NACHT PF05729.7 KFH48338.1 - 0.098 12.3 0.9 19 4.8 0.0 3.4 3 0 0 3 3 3 0 NACHT domain SKI PF01202.17 KFH48338.1 - 0.13 12.1 1.0 67 3.3 0.0 3.6 3 0 0 3 3 3 0 Shikimate kinase SRP54 PF00448.17 KFH48338.1 - 0.14 11.5 7.0 0.32 10.4 0.0 4.0 5 0 0 5 5 4 0 SRP54-type protein, GTPase domain ADK PF00406.17 KFH48338.1 - 0.14 12.0 0.2 19 5.1 0.0 2.7 2 0 0 2 2 2 0 Adenylate kinase KaiC PF06745.8 KFH48338.1 - 0.99 8.4 3.8 19 4.2 0.0 3.4 3 0 0 3 3 3 0 KaiC ResIII PF04851.10 KFH48338.1 - 1 9.1 3.4 22 4.8 0.0 4.0 4 2 1 5 5 3 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 KFH48339.1 - 2.9e-50 170.1 0.1 5.3e-24 85.0 0.0 2.6 3 0 0 3 3 2 2 ABC transporter ABC2_membrane PF01061.19 KFH48339.1 - 6.7e-47 159.3 35.7 2e-26 92.5 8.0 3.1 3 0 0 3 3 3 2 ABC-2 type transporter AAA_21 PF13304.1 KFH48339.1 - 3.6e-19 69.8 0.7 0.00014 21.9 0.0 4.2 4 0 0 4 4 4 4 AAA domain AAA_16 PF13191.1 KFH48339.1 - 1.5e-09 38.1 0.3 0.0022 18.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 KFH48339.1 - 8.7e-09 34.9 0.3 0.0012 18.1 0.1 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KFH48339.1 - 1.1e-08 34.7 0.1 0.0013 18.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 KFH48339.1 - 3.4e-08 32.8 0.6 0.0054 15.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 KFH48339.1 - 8.8e-08 32.7 0.9 0.0011 19.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KFH48339.1 - 2.3e-07 30.2 4.8 0.0064 15.9 0.3 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_15 PF13175.1 KFH48339.1 - 9.6e-07 28.1 0.0 0.37 9.7 0.0 4.1 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 KFH48339.1 - 1.3e-06 28.6 0.6 0.056 13.5 0.0 3.3 3 1 0 3 3 3 2 AAA domain NACHT PF05729.7 KFH48339.1 - 5.8e-06 26.0 0.1 0.14 11.8 0.1 2.5 2 0 0 2 2 2 2 NACHT domain FtsK_SpoIIIE PF01580.13 KFH48339.1 - 7.8e-06 25.5 1.1 0.0043 16.5 0.1 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family SbcCD_C PF13558.1 KFH48339.1 - 1.3e-05 25.0 0.5 0.24 11.3 0.0 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit T2SE PF00437.15 KFH48339.1 - 3.1e-05 23.0 0.4 0.18 10.6 0.0 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_10 PF12846.2 KFH48339.1 - 3.3e-05 23.4 2.8 0.043 13.2 0.1 2.4 2 0 0 2 2 2 2 AAA-like domain AAA_19 PF13245.1 KFH48339.1 - 3.5e-05 23.4 0.2 0.065 12.9 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 KFH48339.1 - 4e-05 24.4 0.0 0.62 10.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 KFH48339.1 - 5.6e-05 23.1 4.8 0.11 12.4 0.2 3.5 4 0 0 4 4 3 2 AAA domain AAA_30 PF13604.1 KFH48339.1 - 6.6e-05 22.5 0.3 0.15 11.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 KFH48339.1 - 0.00013 22.0 0.1 0.66 10.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Arch_ATPase PF01637.13 KFH48339.1 - 0.00017 21.3 0.0 0.078 12.6 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase PDR_CDR PF06422.7 KFH48339.1 - 0.00022 20.8 0.1 0.00052 19.6 0.0 1.5 1 0 0 1 1 1 1 CDR ABC transporter cobW PF02492.14 KFH48339.1 - 0.00072 19.0 3.3 0.32 10.4 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 KFH48339.1 - 0.00091 19.5 0.1 2.4 8.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KFH48339.1 - 0.0016 18.3 0.1 3 7.7 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.1 KFH48339.1 - 0.0016 18.0 0.3 1.9 8.0 0.1 2.3 2 0 0 2 2 2 2 AAA domain NTPase_1 PF03266.10 KFH48339.1 - 0.0018 17.9 0.6 0.72 9.5 0.1 3.6 4 0 0 4 4 4 1 NTPase Miro PF08477.8 KFH48339.1 - 0.0021 18.5 0.2 2.9 8.4 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein MobB PF03205.9 KFH48339.1 - 0.0035 17.0 0.3 2.8 7.6 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 KFH48339.1 - 0.0038 16.7 0.7 0.83 9.1 0.1 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 KFH48339.1 - 0.0059 16.5 0.8 3.5 7.6 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.1 KFH48339.1 - 0.011 15.5 0.1 3.8 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KFH48339.1 - 0.013 15.2 0.7 7.4 6.2 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF3087 PF11286.3 KFH48339.1 - 0.025 13.8 0.2 0.087 12.0 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) Pox_A32 PF04665.7 KFH48339.1 - 0.027 13.7 0.8 1.5 8.0 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein IstB_IS21 PF01695.12 KFH48339.1 - 0.034 13.5 0.4 2.4 7.5 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein Septin PF00735.13 KFH48339.1 - 0.038 12.9 0.4 1.1 8.2 0.0 2.2 2 0 0 2 2 2 0 Septin PRK PF00485.13 KFH48339.1 - 0.06 12.9 0.2 3.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family PduV-EutP PF10662.4 KFH48339.1 - 0.067 12.6 0.6 12 5.3 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation UPF0079 PF02367.12 KFH48339.1 - 0.074 12.6 0.8 7.7 6.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 KFH48339.1 - 0.076 13.2 0.6 7.7 6.7 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KFH48339.1 - 0.079 12.1 0.5 3.3 6.8 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein Zeta_toxin PF06414.7 KFH48339.1 - 0.11 11.5 0.6 4.8 6.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin DUF4388 PF14332.1 KFH48339.1 - 0.12 12.2 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4388) SRPRB PF09439.5 KFH48339.1 - 0.16 11.1 0.6 11 5.2 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit SRP54 PF00448.17 KFH48339.1 - 0.19 11.1 1.4 9.3 5.6 0.2 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ABC_ATPase PF09818.4 KFH48339.1 - 0.21 10.1 0.7 7.1 5.0 0.1 2.8 3 0 0 3 3 3 0 Predicted ATPase of the ABC class DUF2075 PF09848.4 KFH48339.1 - 0.52 9.2 0.2 13 4.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Dynamin_N PF00350.18 KFH48339.1 - 0.69 9.7 1.5 31 4.3 0.1 2.6 3 0 0 3 3 2 0 Dynamin family TrwB_AAD_bind PF10412.4 KFH48339.1 - 0.71 8.4 2.2 1.9 7.0 0.2 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Sec7 PF01369.15 KFH48340.1 - 3.2e-44 150.9 0.0 8.7e-44 149.4 0.0 1.7 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.1 KFH48340.1 - 9.2e-20 70.9 0.0 1.9e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain IKI3 PF04762.7 KFH48341.1 - 0 1046.5 0.0 0 1046.2 0.0 1.1 1 0 0 1 1 1 1 IKI3 family Apc4_WD40 PF12894.2 KFH48341.1 - 0.053 13.0 0.0 0.55 9.7 0.0 2.7 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain TPR_8 PF13181.1 KFH48341.1 - 0.061 13.1 2.7 0.26 11.1 0.2 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFH48341.1 - 6.3 6.9 9.0 1.6 8.8 0.7 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Grp1_Fun34_YaaH PF01184.14 KFH48343.1 - 1.4e-50 171.5 15.3 2e-50 171.0 10.6 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3796 PF12676.2 KFH48343.1 - 0.19 11.9 6.5 0.43 10.8 4.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) DUF2306 PF10067.4 KFH48343.1 - 0.29 11.2 6.0 0.62 10.2 4.2 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2306) DUF1772 PF08592.6 KFH48343.1 - 3.1 7.5 11.8 1.2 8.8 5.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Arch_ATPase PF01637.13 KFH48344.1 - 4.3e-10 39.6 0.0 6.8e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 KFH48344.1 - 6e-07 29.6 1.0 9e-06 25.7 0.2 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KFH48344.1 - 0.0043 17.2 0.0 0.0087 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KFH48344.1 - 0.013 15.0 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 KFH48344.1 - 0.033 13.5 0.0 0.13 11.6 0.0 1.9 2 1 0 2 2 2 0 AAA domain Miro PF08477.8 KFH48344.1 - 0.059 13.8 0.1 0.76 10.2 0.0 2.5 2 1 0 2 2 2 0 Miro-like protein DAP3 PF10236.4 KFH48344.1 - 0.098 11.5 0.2 3.2 6.5 0.0 2.4 2 1 1 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 Gti1_Pac2 PF09729.4 KFH48345.1 - 6.4e-50 169.2 2.5 1.1e-47 162.0 1.8 2.3 1 1 0 1 1 1 1 Gti1/Pac2 family PAT1 PF09770.4 KFH48345.1 - 3.1 5.9 26.8 4 5.5 18.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 APH PF01636.18 KFH48347.1 - 3.1e-12 46.7 0.0 2.5e-11 43.7 0.0 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family AMP-binding PF00501.23 KFH48348.1 - 2e-82 276.8 0.1 4.9e-81 272.2 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 KFH48348.1 - 4.5e-61 206.3 0.0 1.8e-35 122.2 0.0 2.5 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 KFH48348.1 - 5.3e-28 97.0 0.0 9.8e-13 48.1 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site RRM_1 PF00076.17 KFH48349.1 - 1.1e-14 53.7 0.0 2.1e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH48349.1 - 3e-11 43.1 0.0 5.7e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH48349.1 - 2.5e-09 36.8 0.1 4.3e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FMO-like PF00743.14 KFH48350.1 - 9.3e-52 175.9 0.0 2.2e-51 174.6 0.0 1.4 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KFH48350.1 - 1.8e-25 90.2 0.0 4.8e-24 85.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFH48350.1 - 3.1e-10 40.0 0.0 4.5e-08 33.0 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KFH48350.1 - 1.6e-07 30.5 0.0 1.4e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KFH48350.1 - 3.1e-07 30.4 0.0 6.4e-06 26.1 0.0 2.4 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KFH48350.1 - 1.2e-05 24.4 0.7 0.043 12.7 0.3 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_2 PF03446.10 KFH48350.1 - 3.7e-05 23.6 0.5 0.00012 21.9 0.1 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 KFH48350.1 - 0.00018 20.7 0.0 0.29 10.2 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 KFH48350.1 - 0.00023 21.1 0.0 0.00062 19.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KFH48350.1 - 0.00051 20.3 1.5 0.11 12.9 0.1 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KFH48350.1 - 0.0011 18.5 0.8 0.067 12.7 0.1 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 KFH48350.1 - 0.0031 17.6 0.1 3.9 7.5 0.0 2.8 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.16 KFH48350.1 - 0.0082 15.7 0.0 0.95 8.9 0.0 2.2 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.13 KFH48350.1 - 0.02 14.9 2.8 0.67 9.9 0.1 2.5 2 0 0 2 2 2 0 TrkA-N domain IlvN PF07991.7 KFH48350.1 - 0.027 13.8 0.2 0.29 10.4 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 KFH48350.1 - 0.034 13.7 3.7 0.15 11.7 0.3 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amino_oxidase PF01593.19 KFH48350.1 - 0.041 12.9 0.0 7.5 5.4 0.0 3.0 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase ThiF PF00899.16 KFH48350.1 - 0.047 13.5 3.8 0.67 9.7 0.1 2.3 2 0 0 2 2 2 0 ThiF family NAD_binding_10 PF13460.1 KFH48350.1 - 0.11 12.4 0.0 0.41 10.6 0.0 1.9 2 0 0 2 2 2 0 NADH(P)-binding HI0933_like PF03486.9 KFH48350.1 - 0.14 10.6 0.0 7.9 4.8 0.2 2.2 2 0 0 2 2 2 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.9 KFH48350.1 - 0.16 11.3 0.2 0.32 10.3 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Abhydrolase_6 PF12697.2 KFH48351.1 - 1e-23 84.3 1.9 1e-23 84.3 1.3 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH48351.1 - 1.1e-09 38.2 0.0 1.9e-09 37.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFH48351.1 - 1.7e-08 34.2 0.0 2.6e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KFH48351.1 - 0.001 18.8 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase RskA PF10099.4 KFH48351.1 - 0.0097 15.6 0.2 0.11 12.2 0.2 2.4 2 0 0 2 2 2 1 Anti-sigma-K factor rskA Lipase_3 PF01764.20 KFH48351.1 - 0.013 15.0 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DLH PF01738.13 KFH48351.1 - 0.031 13.5 0.0 0.089 12.0 0.0 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family AXE1 PF05448.7 KFH48351.1 - 0.045 12.2 0.0 0.062 11.7 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Thioesterase PF00975.15 KFH48351.1 - 1.3 9.2 3.2 1.1 9.3 1.0 1.7 2 0 0 2 2 2 0 Thioesterase domain DASH_Spc34 PF08657.5 KFH48352.1 - 2.7e-47 161.6 9.5 4.1e-46 157.7 6.6 2.0 1 1 0 1 1 1 1 DASH complex subunit Spc34 Daxx PF03344.10 KFH48352.1 - 0.1 11.0 17.3 0.18 10.2 12.0 1.3 1 0 0 1 1 1 0 Daxx Family Pox_RNA_Pol_19 PF05320.7 KFH48352.1 - 0.29 10.8 9.1 0.49 10.1 6.3 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit CobT PF06213.7 KFH48352.1 - 0.3 10.1 18.4 0.44 9.6 12.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.7 KFH48352.1 - 0.33 10.1 12.4 0.5 9.5 8.6 1.2 1 0 0 1 1 1 0 NOA36 protein Nop53 PF07767.6 KFH48352.1 - 0.67 8.8 18.1 1.1 8.2 12.6 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Paf1 PF03985.8 KFH48352.1 - 0.75 8.4 18.6 1.1 7.9 12.9 1.1 1 0 0 1 1 1 0 Paf1 Nop14 PF04147.7 KFH48352.1 - 1.1 7.0 20.2 1.5 6.6 14.0 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KFH48352.1 - 2.1 6.2 19.4 2.8 5.8 13.5 1.1 1 0 0 1 1 1 0 CDC45-like protein VID27 PF08553.5 KFH48352.1 - 2.1 6.4 19.3 2.7 6.0 13.3 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein SDA1 PF05285.7 KFH48352.1 - 2.7 7.1 20.9 4 6.6 14.5 1.2 1 0 0 1 1 1 0 SDA1 DUF4011 PF13195.1 KFH48352.1 - 4.2 7.3 8.4 3.6 7.5 4.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) TEX19 PF15553.1 KFH48352.1 - 6.4 6.6 10.5 11 5.9 7.3 1.3 1 0 0 1 1 1 0 Testis-expressed protein 19 MOZ_SAS PF01853.13 KFH48353.1 - 2e-48 164.1 0.0 5.2e-48 162.7 0.0 1.6 1 1 0 1 1 1 1 MOZ/SAS family VID27 PF08553.5 KFH48355.1 - 0 1097.1 0.1 0 1097.0 0.0 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein DEAD PF00270.24 KFH48356.1 - 6.5e-43 146.1 0.0 9e-43 145.6 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFH48356.1 - 9.6e-24 83.0 0.1 9.6e-24 83.0 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GRP PF07172.6 KFH48356.1 - 3.4 8.1 20.0 6.9 7.2 13.9 1.5 1 0 0 1 1 1 0 Glycine rich protein family TBCC PF07986.7 KFH48357.1 - 2.3e-29 101.2 0.2 1.2e-28 98.9 0.2 2.0 1 1 0 1 1 1 1 Tubulin binding cofactor C Cu_bind_like PF02298.12 KFH48358.1 - 0.014 15.1 0.1 0.059 13.1 0.1 1.9 1 1 0 1 1 1 0 Plastocyanin-like domain ABC_membrane PF00664.18 KFH48359.1 - 4.5e-35 121.4 11.6 5.6e-35 121.0 8.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KFH48359.1 - 7e-34 117.0 0.0 1.9e-33 115.6 0.0 1.8 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 KFH48359.1 - 1.5e-07 31.7 0.1 0.017 15.1 0.0 2.7 2 1 1 3 3 3 2 AAA domain SMC_N PF02463.14 KFH48359.1 - 1.7e-05 24.2 0.0 0.0045 16.2 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 KFH48359.1 - 3.9e-05 23.2 0.0 0.0008 18.9 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain AAA_16 PF13191.1 KFH48359.1 - 5.2e-05 23.3 0.0 0.0003 20.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KFH48359.1 - 0.00014 22.6 0.0 0.00034 21.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 KFH48359.1 - 0.00055 19.1 0.0 0.00099 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 KFH48359.1 - 0.00069 19.5 0.0 0.0035 17.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KFH48359.1 - 0.001 19.2 0.0 0.0045 17.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KFH48359.1 - 0.0031 16.9 0.0 0.0077 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KFH48359.1 - 0.0031 17.0 0.0 0.008 15.6 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 KFH48359.1 - 0.012 15.9 0.0 0.048 13.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KFH48359.1 - 0.012 15.3 0.0 0.04 13.6 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KFH48359.1 - 0.013 15.3 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KFH48359.1 - 0.015 14.3 0.0 0.044 12.8 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 KFH48359.1 - 0.016 15.1 0.1 0.046 13.6 0.0 1.8 1 1 1 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KFH48359.1 - 0.028 14.3 0.0 0.062 13.2 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.24 KFH48359.1 - 0.039 14.1 0.0 0.19 11.9 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 KFH48359.1 - 0.04 13.8 0.2 0.38 10.6 0.1 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Miro PF08477.8 KFH48359.1 - 0.041 14.3 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein DUF1016 PF06250.6 KFH48359.1 - 0.045 12.7 0.0 0.073 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1016) DUF87 PF01935.12 KFH48359.1 - 0.052 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 NACHT PF05729.7 KFH48359.1 - 0.079 12.6 0.1 0.22 11.1 0.0 1.8 2 0 0 2 2 1 0 NACHT domain NB-ARC PF00931.17 KFH48359.1 - 0.093 11.5 0.1 0.21 10.4 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.1 KFH48359.1 - 0.096 12.9 0.5 0.19 12.0 0.0 1.7 2 0 0 2 2 1 0 AAA domain Vma12 PF11712.3 KFH48360.1 - 1.6e-38 131.5 0.0 2.4e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase zf-C3HC4_3 PF13920.1 KFH48361.1 - 0.00059 19.4 8.3 0.00096 18.7 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFH48361.1 - 0.042 13.5 7.5 0.081 12.5 5.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFH48361.1 - 0.17 11.7 11.5 0.32 10.8 8.0 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 KFH48361.1 - 0.17 11.9 10.3 0.32 11.0 7.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4098 PF13345.1 KFH48362.1 - 0.0016 18.3 10.3 0.89 9.5 3.2 5.5 3 2 0 3 3 3 2 Domain of unknown function (DUF4098) Spc7 PF08317.6 KFH48363.1 - 0.0064 15.1 5.3 0.0099 14.5 3.7 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein V_ATPase_I PF01496.14 KFH48363.1 - 0.011 13.6 2.7 0.016 13.0 1.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 KFH48363.1 - 0.099 11.5 6.0 0.17 10.7 4.1 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 KFH48363.1 - 0.23 11.0 14.3 2.6 7.6 10.0 2.1 1 1 0 1 1 1 0 IncA protein GAS PF13851.1 KFH48363.1 - 0.24 10.5 5.1 0.42 9.7 3.6 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.3 KFH48363.1 - 1.2 9.0 7.2 36 4.2 0.5 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Angiomotin_C PF12240.3 KFH48363.1 - 2.2 7.7 15.4 0.23 10.9 7.1 1.9 2 1 0 2 2 2 0 Angiomotin C terminal DUF1192 PF06698.6 KFH48363.1 - 5 7.0 9.2 0.082 12.7 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF4140 PF13600.1 KFH48363.1 - 8.3 6.9 9.4 19 5.7 1.1 2.7 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF641 PF04859.7 KFH48363.1 - 8.8 6.1 7.9 14 5.4 2.7 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) CENP-Q PF13094.1 KFH48363.1 - 8.8 6.3 16.1 0.36 10.8 1.8 3.0 2 1 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit ARID PF01388.16 KFH48364.1 - 4.4e-09 36.0 0.0 1.9e-08 34.0 0.0 2.1 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain UDPGT PF00201.13 KFH48365.1 - 7.9e-10 37.8 0.0 3.4e-08 32.4 0.0 2.1 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.15 KFH48365.1 - 0.00064 19.5 0.3 0.001 18.8 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.11 KFH48365.1 - 0.006 16.2 0.0 0.009 15.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 KFH48365.1 - 0.21 10.7 0.0 4.6 6.3 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 1 6PF2K PF01591.13 KFH48366.1 - 3.2e-79 265.1 0.0 4e-79 264.7 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KFH48366.1 - 1.7e-30 106.2 0.0 4.8e-30 104.7 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KFH48366.1 - 1.2e-10 41.4 0.1 2.4e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFH48366.1 - 3.3e-05 24.6 0.5 0.0012 19.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 KFH48366.1 - 0.0004 19.6 0.0 0.0006 19.0 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 F-box-like PF12937.2 KFH48367.1 - 0.00044 19.9 0.1 0.00079 19.1 0.1 1.4 1 0 0 1 1 1 1 F-box-like DUF829 PF05705.9 KFH48369.1 - 1.5e-43 149.2 0.0 1.8e-43 148.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.2 KFH48369.1 - 0.00016 21.6 3.1 0.00023 21.1 2.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF155 PF02582.9 KFH48370.1 - 1.1e-37 129.5 0.0 1.5e-37 129.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF3767 PF12597.3 KFH48371.1 - 2.9e-34 117.2 0.1 3.9e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) DUF3529 PF12046.3 KFH48371.1 - 0.046 12.7 0.0 0.057 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3529) Linker_histone PF00538.14 KFH48373.1 - 2.6e-24 85.1 0.3 7.8e-24 83.5 0.2 1.8 1 0 0 1 1 1 1 linker histone H1 and H5 family Menin PF05053.8 KFH48373.1 - 1 7.4 10.1 1.2 7.2 7.0 1.3 1 0 0 1 1 1 0 Menin PCAF_N PF06466.6 KFH48373.1 - 1.2 8.3 0.0 1.2 8.3 0.0 2.0 2 0 0 2 2 2 0 PCAF (P300/CBP-associated factor) N-terminal domain DUF3140 PF11338.3 KFH48374.1 - 9.8e-32 108.9 1.0 9.8e-32 108.9 0.7 3.1 2 1 2 4 4 4 1 Protein of unknown function (DUF3140) DUF2945 PF11160.3 KFH48374.1 - 0.01 15.6 3.1 0.01 15.6 2.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2945) Nop14 PF04147.7 KFH48374.1 - 0.13 10.1 18.9 0.16 9.8 13.1 1.2 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.7 KFH48374.1 - 0.19 11.4 20.8 0.36 10.5 14.4 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Dicty_REP PF05086.7 KFH48374.1 - 4.6 4.8 10.2 5.8 4.5 7.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pkinase PF00069.20 KFH48375.1 - 1.6e-70 237.2 0.0 4.2e-70 235.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH48375.1 - 1.4e-30 106.2 0.0 3.1e-22 78.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KFH48375.1 - 1.7e-06 27.2 0.0 0.45 9.4 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Kdo PF06293.9 KFH48375.1 - 0.016 14.2 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFH48375.1 - 0.052 13.2 0.0 1.8 8.2 0.0 2.4 2 1 0 3 3 3 0 Phosphotransferase enzyme family RabGAP-TBC PF00566.13 KFH48376.1 - 5.6e-49 166.5 0.0 9.2e-49 165.8 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain TRI12 PF06609.8 KFH48377.1 - 2.2e-25 88.9 16.6 2.8e-25 88.5 11.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KFH48377.1 - 1.6e-23 83.0 41.6 2.5e-23 82.3 27.1 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Pox_A14 PF05767.7 KFH48377.1 - 0.45 10.5 0.0 0.45 10.5 0.0 2.9 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 TauD PF02668.11 KFH48378.1 - 1.1e-45 156.3 0.3 1.3e-45 156.1 0.2 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Glyco_hydro_3 PF00933.16 KFH48379.1 - 1.8e-35 122.3 0.0 2.4e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Asp_protease_2 PF13650.1 KFH48380.1 - 9.1e-13 48.5 0.0 3.8e-07 30.5 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.1 KFH48380.1 - 0.028 14.2 0.1 0.84 9.5 0.0 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF805 PF05656.9 KFH48381.1 - 0.36 10.6 3.5 1.5 8.6 2.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF805) zf-4CXXC_R1 PF10497.4 KFH48382.1 - 0.34 11.0 4.4 0.53 10.4 0.4 2.6 2 2 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Hexapep PF00132.19 KFH48384.1 - 7e-08 31.6 4.4 2.6e-05 23.5 0.1 3.2 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KFH48384.1 - 0.00034 20.7 0.0 0.0012 18.9 0.0 1.9 2 1 0 2 2 2 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 KFH48384.1 - 0.0081 15.7 9.1 0.46 10.0 0.2 3.7 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.18 KFH48384.1 - 0.052 12.8 0.0 0.092 12.0 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyl transferase Fucokinase PF07959.7 KFH48384.1 - 0.3 9.5 1.1 1.3 7.4 0.8 1.8 1 1 0 1 1 1 0 L-fucokinase Abhydrolase_3 PF07859.8 KFH48385.1 - 1.6e-62 210.8 0.0 2.1e-62 210.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KFH48385.1 - 2.5e-07 29.7 0.3 4e-07 29.1 0.0 1.3 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.16 KFH48385.1 - 5.8e-07 28.9 0.0 8.9e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2424 PF10340.4 KFH48385.1 - 0.046 12.3 0.0 0.15 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) R3H PF01424.17 KFH48387.1 - 2.6e-11 43.0 0.4 4.5e-11 42.2 0.3 1.4 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 KFH48387.1 - 5.1e-07 29.5 0.1 8.8e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH48387.1 - 3.5e-05 23.5 0.4 9.2e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFH48387.1 - 0.00012 21.6 0.0 0.00029 20.4 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Milton PF12448.3 KFH48387.1 - 0.18 12.0 4.9 1 9.5 0.3 3.4 2 1 0 2 2 2 0 Kinesin associated protein SQS_PSY PF00494.14 KFH48388.1 - 6.6e-54 182.9 0.0 1.1e-53 182.2 0.0 1.3 1 1 0 1 1 1 1 Squalene/phytoene synthase Ribosomal_S6 PF01250.12 KFH48388.1 - 4.3e-11 42.5 0.0 7.2e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S6 Peptidase_M24 PF00557.19 KFH48388.1 - 0.13 11.8 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 Metallopeptidase family M24 Pkinase PF00069.20 KFH48389.1 - 2.5e-38 131.7 0.0 3.8e-38 131.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH48389.1 - 2.8e-18 65.9 0.0 1.5e-17 63.5 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KFH48389.1 - 2.5e-07 30.6 0.1 9.1e-07 28.8 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFH48389.1 - 0.0022 17.3 0.0 0.0064 15.8 0.0 1.4 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 KFH48389.1 - 0.015 14.9 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 KFH48389.1 - 0.019 14.3 0.0 0.064 12.5 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kdo PF06293.9 KFH48389.1 - 0.051 12.6 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KFH48389.1 - 0.11 11.2 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase SDA1 PF05285.7 KFH48390.1 - 3.5e-91 305.8 47.2 4.7e-91 305.4 26.2 2.8 3 0 0 3 3 3 2 SDA1 NUC130_3NT PF08158.7 KFH48390.1 - 1.8e-20 72.9 0.1 6e-20 71.2 0.0 2.0 2 0 0 2 2 2 1 NUC130/3NT domain Dict-STAT-coil PF09267.5 KFH48390.1 - 0.054 13.7 0.2 0.15 12.2 0.2 1.7 1 0 0 1 1 1 0 Dictyostelium STAT, coiled coil MFS_1 PF07690.11 KFH48392.1 - 2.8e-25 88.7 38.9 4.6e-25 88.0 27.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily JmjC PF02373.17 KFH48393.1 - 9.2e-38 128.9 0.5 3.1e-37 127.3 0.3 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 KFH48393.1 - 1.4e-20 73.3 6.7 2.5e-20 72.5 4.7 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KFH48393.1 - 9.5e-20 70.5 7.5 9.5e-20 70.5 5.2 2.2 2 0 0 2 2 2 1 PHD-like zinc-binding domain JmjN PF02375.12 KFH48393.1 - 2.5e-15 55.6 0.4 5.5e-15 54.5 0.3 1.6 1 0 0 1 1 1 1 jmjN domain Pox_RNA_Pol_19 PF05320.7 KFH48393.1 - 0.21 11.3 0.8 0.54 9.9 0.5 1.6 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Ala_racemase_N PF01168.15 KFH48394.1 - 2.4e-28 99.1 0.1 3e-28 98.8 0.1 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.1 KFH48394.1 - 5.5e-21 74.5 0.0 1.1e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 Putative serine dehydratase domain SDH_alpha PF03313.10 KFH48394.1 - 3.1e-05 23.1 0.1 0.19 10.7 0.0 2.4 2 0 0 2 2 2 2 Serine dehydratase alpha chain GTP_CH_N PF12471.3 KFH48394.1 - 0.088 12.4 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 GTP cyclohydrolase N terminal ADH_N PF08240.7 KFH48398.1 - 9.6e-22 76.8 2.6 1.5e-21 76.2 1.8 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFH48398.1 - 5.6e-21 74.4 0.0 8.4e-21 73.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFH48398.1 - 1.7e-06 28.9 0.0 3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 KFH48398.1 - 0.0075 16.3 0.0 0.014 15.4 0.0 1.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 KFH48398.1 - 0.018 14.1 0.1 0.03 13.4 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF2953 PF11167.3 KFH48399.1 - 0.013 15.3 0.4 0.063 13.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) Arginosuc_synth PF00764.14 KFH48400.1 - 2.2e-45 155.3 0.0 3.4e-45 154.7 0.0 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase Amino_oxidase PF01593.19 KFH48400.1 - 5e-33 114.8 0.1 2.2e-20 73.2 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KFH48400.1 - 2.7e-10 40.1 0.0 8.2e-10 38.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Asn_synthase PF00733.16 KFH48400.1 - 1e-05 25.2 0.0 2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase Pyr_redox_3 PF13738.1 KFH48400.1 - 0.00045 20.3 0.0 0.0013 18.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KFH48400.1 - 0.23 10.9 0.0 0.51 9.8 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain QueC PF06508.8 KFH48400.1 - 0.3 10.3 0.0 0.48 9.6 0.0 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC DUF1977 PF09320.6 KFH48401.1 - 2.4e-24 85.6 0.1 4.5e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 KFH48401.1 - 1.5e-20 72.6 0.2 2.6e-20 71.9 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain HTH_29 PF13551.1 KFH48401.1 - 0.15 12.2 0.0 0.15 12.2 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn helix Fungal_trans PF04082.13 KFH48402.1 - 2.9e-25 88.6 0.0 5.4e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH48402.1 - 6.6e-08 32.3 13.7 1.3e-07 31.4 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_BLRF2 PF05812.7 KFH48402.1 - 0.031 14.0 0.3 0.058 13.2 0.2 1.4 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein TSC22 PF01166.13 KFH48402.1 - 0.12 12.3 0.4 0.25 11.3 0.3 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family NUDIX PF00293.23 KFH48403.1 - 3e-15 56.0 0.6 4.4e-15 55.5 0.4 1.1 1 0 0 1 1 1 1 NUDIX domain FAD_binding_3 PF01494.14 KFH48404.1 - 3.1e-17 62.6 0.2 9.2e-10 38.0 0.1 2.5 2 1 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.19 KFH48404.1 - 5.7e-07 28.7 0.1 1.1e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFH48404.1 - 6.6e-07 28.5 0.1 0.0002 20.4 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFH48404.1 - 6.7e-06 26.0 0.2 1.5e-05 24.9 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFH48404.1 - 9.1e-05 22.4 0.0 0.00018 21.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFH48404.1 - 0.0004 20.5 0.0 0.00068 19.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFH48404.1 - 0.0015 17.7 0.0 0.0023 17.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 KFH48404.1 - 0.002 17.0 0.1 0.0029 16.5 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 KFH48404.1 - 0.0021 17.2 0.1 0.0034 16.5 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFH48404.1 - 0.0025 18.1 0.1 0.0065 16.8 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFH48404.1 - 0.0045 15.9 0.5 0.12 11.3 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.9 KFH48404.1 - 0.0051 15.3 0.2 0.0074 14.7 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.9 KFH48404.1 - 0.017 13.7 0.0 0.24 10.0 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.16 KFH48404.1 - 0.026 14.0 0.0 0.054 13.0 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.19 KFH48404.1 - 0.044 12.8 0.2 0.099 11.6 0.0 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Tcp11 PF05794.8 KFH48406.1 - 4.1e-46 157.6 0.9 2.3e-45 155.1 0.0 2.0 2 0 0 2 2 2 1 T-complex protein 11 Methyltransf_2 PF00891.13 KFH48407.1 - 1.5e-20 73.4 0.0 2.2e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Fungal_trans_2 PF11951.3 KFH48408.1 - 6.3e-22 77.7 0.2 8.2e-22 77.3 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-TRAF PF02176.13 KFH48409.1 - 2.4e-10 40.6 29.3 6.4e-09 36.0 2.1 4.0 2 1 2 4 4 3 3 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 KFH48409.1 - 3.6e-09 36.4 5.2 3.6e-09 36.4 3.6 3.6 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFH48409.1 - 1.1e-08 34.5 4.2 1.1e-08 34.5 2.9 3.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFH48409.1 - 3e-08 33.3 6.0 3e-08 33.3 4.2 3.0 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KFH48409.1 - 9.3e-08 31.7 5.9 9.3e-08 31.7 4.1 3.4 2 1 2 4 4 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFH48409.1 - 1.3e-06 27.9 2.3 1.3e-06 27.9 1.6 3.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFH48409.1 - 2.5e-06 27.1 3.1 2.5e-06 27.1 2.2 3.5 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KFH48409.1 - 0.00075 19.1 4.1 0.00075 19.1 2.8 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.3 KFH48409.1 - 0.0072 15.8 2.8 0.0072 15.8 2.0 2.3 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 KFH48409.1 - 0.032 13.9 2.4 0.099 12.4 1.7 1.9 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 KFH48409.1 - 0.048 13.5 0.5 0.048 13.5 0.3 2.6 2 1 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Sina PF03145.11 KFH48409.1 - 0.048 13.3 19.9 0.085 12.5 0.1 3.5 2 1 1 3 3 3 0 Seven in absentia protein family Cortex-I_coil PF09304.5 KFH48409.1 - 0.057 13.4 3.3 0.22 11.5 0.6 2.5 2 1 0 2 2 2 0 Cortexillin I, coiled coil Uds1 PF15456.1 KFH48409.1 - 0.21 11.6 3.9 0.36 10.8 1.0 2.4 1 1 1 2 2 2 0 Up-regulated During Septation ADH_zinc_N_2 PF13602.1 KFH48410.1 - 3.6e-19 69.9 0.0 5.8e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KFH48410.1 - 2e-11 43.5 0.0 6.6e-11 41.8 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFH48410.1 - 0.11 12.3 0.0 0.27 11.0 0.0 1.7 1 1 1 2 2 2 0 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 KFH48410.1 - 0.11 12.5 0.1 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Ima1_N PF09779.4 KFH48412.1 - 3.1e-36 124.7 1.4 5.3e-36 124.0 1.0 1.4 1 0 0 1 1 1 1 Ima1 N-terminal domain DZR PF12773.2 KFH48412.1 - 0.0078 16.0 3.6 0.23 11.3 0.3 2.4 2 0 0 2 2 2 2 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 KFH48412.1 - 0.12 12.1 5.5 0.097 12.4 1.6 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 KFH48412.1 - 0.75 9.4 6.3 0.082 12.5 1.1 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DUF4187 PF13821.1 KFH48412.1 - 1.1 8.8 4.1 0.54 9.8 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) AAA PF00004.24 KFH48413.1 - 9.2e-44 148.8 0.0 1.5e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFH48413.1 - 5e-08 32.7 0.0 1.2e-07 31.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KFH48413.1 - 2.5e-07 30.7 0.0 4.5e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KFH48413.1 - 2.2e-06 27.8 0.1 6.9e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFH48413.1 - 9.5e-06 25.7 0.1 0.00051 20.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFH48413.1 - 0.00011 21.8 0.1 0.00024 20.7 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KFH48413.1 - 0.00013 21.4 0.0 0.00023 20.6 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 KFH48413.1 - 0.00014 21.0 0.0 0.00024 20.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KFH48413.1 - 0.00028 21.7 0.0 0.00067 20.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 KFH48413.1 - 0.0015 17.3 0.0 0.0027 16.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 KFH48413.1 - 0.0016 18.2 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KFH48413.1 - 0.002 18.0 0.0 0.0032 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFH48413.1 - 0.0021 17.1 0.0 0.0039 16.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 KFH48413.1 - 0.0032 16.8 0.1 0.016 14.6 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.1 KFH48413.1 - 0.005 16.8 0.0 0.0086 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KFH48413.1 - 0.0056 15.8 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_18 PF13238.1 KFH48413.1 - 0.0057 16.9 0.0 0.028 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KFH48413.1 - 0.0065 15.6 0.1 0.014 14.6 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KFH48413.1 - 0.0068 16.0 0.0 0.02 14.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 KFH48413.1 - 0.011 14.6 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.11 KFH48413.1 - 0.016 14.4 0.0 0.049 12.8 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.1 KFH48413.1 - 0.017 14.6 0.1 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KFH48413.1 - 0.021 14.2 0.0 0.094 12.1 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain RNA_helicase PF00910.17 KFH48413.1 - 0.023 14.8 0.0 0.043 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Histone PF00125.19 KFH48413.1 - 0.047 13.8 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Sigma54_activ_2 PF14532.1 KFH48413.1 - 0.049 13.6 0.0 0.11 12.5 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 KFH48413.1 - 0.054 13.1 0.0 0.28 10.8 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Parvo_NS1 PF01057.12 KFH48413.1 - 0.067 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 KFH48413.1 - 0.08 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Pkinase PF00069.20 KFH48415.1 - 1e-31 110.0 0.0 1.5e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH48415.1 - 5e-16 58.5 0.0 1.3e-14 53.8 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH48415.1 - 0.062 12.2 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like ADH_N PF08240.7 KFH48416.1 - 1.4e-05 24.8 0.8 7.8e-05 22.3 0.1 2.4 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KFH48416.1 - 0.0025 18.7 0.2 0.0082 17.0 0.2 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Abhydrolase_4 PF08386.5 KFH48417.1 - 9.3e-20 70.4 0.0 2.3e-19 69.1 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KFH48417.1 - 1.8e-08 34.2 0.0 0.0002 20.9 0.0 3.2 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KFH48417.1 - 3.8e-08 33.4 0.4 8.1e-07 29.1 0.3 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family AAA_27 PF13514.1 KFH48417.1 - 0.031 12.0 1.1 0.043 11.5 0.8 1.1 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.11 KFH48418.1 - 3.4e-33 114.8 30.0 5.3e-33 114.1 20.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 KFH48418.1 - 0.95 8.9 6.9 0.18 11.2 0.7 2.3 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 DUF2721 PF11026.3 KFH48418.1 - 2 8.0 5.8 7.2 6.2 0.1 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF2721) DUF3080 PF11279.3 KFH48419.1 - 0.05 12.7 1.7 0.16 11.1 1.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) PMEI PF04043.10 KFH48419.1 - 0.052 13.4 0.7 0.16 11.8 0.5 1.9 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor Nitrate_red_del PF02613.10 KFH48419.1 - 0.17 11.6 1.7 0.35 10.6 0.3 2.2 2 0 0 2 2 2 0 Nitrate reductase delta subunit GTP_cyclohydroI PF01227.17 KFH48419.1 - 6.8 5.9 8.2 1.5 8.0 0.4 2.8 2 1 1 3 3 3 0 GTP cyclohydrolase I CAP PF00188.21 KFH48420.1 - 2.7e-20 73.0 0.3 3.6e-20 72.6 0.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family HET PF06985.6 KFH48423.1 - 2.6e-26 92.4 0.5 9e-26 90.6 0.3 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aldo_ket_red PF00248.16 KFH48425.1 - 6e-36 123.7 0.0 7.8e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family CDC24 PF06395.6 KFH48425.1 - 0.026 14.5 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 CDC24 Calponin Pyridoxal_deC PF00282.14 KFH48426.1 - 2.2e-72 243.5 0.0 3.2e-72 243.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF4431 PF14485.1 KFH48426.1 - 0.084 12.4 0.0 0.87 9.2 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4431) rRNA_proc-arch PF13234.1 KFH48427.1 - 2.9e-90 302.0 0.0 4.9e-90 301.3 0.0 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 KFH48427.1 - 9.3e-60 200.9 2.9 1.9e-59 199.9 1.2 2.1 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 KFH48427.1 - 3.3e-22 78.7 0.0 8.6e-22 77.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFH48427.1 - 2.2e-07 30.6 0.0 5.3e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SE PF00437.15 KFH48427.1 - 0.029 13.2 0.0 0.14 10.9 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein Aminotran_3 PF00202.16 KFH48428.1 - 5.9e-95 317.9 0.0 7.2e-95 317.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KFH48428.1 - 0.011 14.7 0.0 0.017 14.1 0.0 1.4 1 1 0 1 1 1 0 Aminotransferase class I and II Acetyltransf_1 PF00583.19 KFH48429.1 - 1.6e-06 28.0 0.0 6.2e-05 22.9 0.0 2.2 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KFH48429.1 - 9.8e-06 25.4 0.1 0.0024 17.7 0.0 3.1 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KFH48429.1 - 1.5e-05 25.0 0.0 0.00049 20.2 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFH48429.1 - 0.0003 20.4 0.0 0.00057 19.5 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KFH48429.1 - 0.0062 16.6 0.0 0.018 15.1 0.0 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain PPR_2 PF13041.1 KFH48430.1 - 1.3e-16 60.2 0.2 5.7e-06 26.2 0.0 4.9 3 1 1 4 4 4 4 PPR repeat family PPR_3 PF13812.1 KFH48430.1 - 3e-13 48.8 10.0 0.0011 19.0 0.0 6.6 8 0 0 8 8 8 4 Pentatricopeptide repeat domain PPR PF01535.15 KFH48430.1 - 1.4e-10 40.3 11.1 0.00011 21.9 0.0 5.4 5 0 0 5 5 5 2 PPR repeat PPR_1 PF12854.2 KFH48430.1 - 0.18 11.2 9.0 6.9 6.2 0.0 4.4 4 1 0 4 4 4 0 PPR repeat WLM PF08325.5 KFH48431.1 - 4.1e-44 150.6 0.0 4.1e-44 150.6 0.0 1.5 2 0 0 2 2 2 1 WLM domain DUF45 PF01863.12 KFH48431.1 - 2.8e-05 24.0 0.5 6.4e-05 22.8 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 Reprolysin_5 PF13688.1 KFH48431.1 - 0.014 15.3 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_MA_2 PF13485.1 KFH48431.1 - 0.063 13.3 0.1 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase MA superfamily SprT-like PF10263.4 KFH48431.1 - 0.087 12.4 0.6 0.14 11.7 0.4 1.3 1 0 0 1 1 1 0 SprT-like family DIT1_PvcA PF05141.7 KFH48432.1 - 1.4e-86 290.2 0.0 1.8e-86 289.9 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.11 KFH48432.1 - 4.4e-25 88.8 0.0 7.3e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Cullin_binding PF03556.10 KFH48433.1 - 4e-31 107.5 8.6 5.4e-31 107.1 5.9 1.1 1 0 0 1 1 1 1 Cullin binding Spt20 PF12090.3 KFH48434.1 - 4.9e-42 143.3 8.7 8.9e-41 139.2 0.0 2.3 2 0 0 2 2 2 2 Spt20 family Ycf1 PF05758.7 KFH48434.1 - 1.8 6.1 8.5 3.6 5.2 5.9 1.4 1 0 0 1 1 1 0 Ycf1 eIF-3_zeta PF05091.7 KFH48434.1 - 3.4 6.1 14.1 7 5.1 9.8 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Spore_coat_CotO PF14153.1 KFH48434.1 - 5.2 6.4 21.6 4.2 6.7 10.5 2.4 2 0 0 2 2 2 0 Spore coat protein CotO DUF4407 PF14362.1 KFH48434.1 - 7.2 5.4 15.4 13 4.5 10.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Aminotran_1_2 PF00155.16 KFH48435.1 - 6.7e-69 232.5 0.0 8.8e-69 232.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KFH48435.1 - 2e-06 27.0 0.0 6e-06 25.5 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 KFH48435.1 - 6.5e-06 25.4 0.0 1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 KFH48435.1 - 0.001 17.4 0.0 0.0018 16.6 0.0 1.3 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KFH48435.1 - 0.02 13.6 0.0 0.044 12.5 0.0 1.7 1 1 0 1 1 1 0 Aminotransferase class-V Amidohydro_3 PF07969.6 KFH48436.1 - 2.9e-54 184.8 1.0 3.5e-54 184.5 0.7 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KFH48436.1 - 3.8e-09 36.2 0.0 1.1e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 KFH48436.1 - 0.00024 21.2 2.8 0.01 15.8 1.9 2.8 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KFH48436.1 - 0.0023 17.6 0.8 1 8.9 0.6 2.9 2 1 0 2 2 2 2 Amidohydrolase family RE_XcyI PF09571.5 KFH48436.1 - 0.035 12.9 0.0 7.1 5.3 0.0 2.2 2 0 0 2 2 2 0 XcyI restriction endonuclease ER_lumen_recept PF00810.13 KFH48437.1 - 2.2e-54 183.9 7.1 3.1e-54 183.4 4.9 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 KFH48437.1 - 1.6 8.2 13.2 1.1 8.8 0.2 3.6 3 1 1 4 4 4 0 PQ loop repeat CorA PF01544.13 KFH48438.1 - 5.4e-29 101.1 3.2 1.4e-25 89.9 0.8 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Lyase_8_N PF08124.6 KFH48438.1 - 0.036 12.9 0.0 0.06 12.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain Alg14 PF08660.6 KFH48439.1 - 4.5e-35 121.1 0.0 6.3e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Amidase PF01425.16 KFH48440.1 - 4.8e-60 203.6 0.7 1.4e-59 202.0 0.5 1.7 1 1 0 1 1 1 1 Amidase ADH_N PF08240.7 KFH48441.1 - 1e-30 105.7 0.9 1.8e-30 104.8 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFH48441.1 - 5e-29 100.4 0.4 7.7e-29 99.8 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KFH48441.1 - 1.3e-05 24.7 0.1 3e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated NAD_binding_7 PF13241.1 KFH48441.1 - 0.00048 20.3 0.9 0.00068 19.8 0.1 1.6 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 KFH48441.1 - 0.0019 18.3 0.2 0.0054 16.8 0.1 1.8 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.1 KFH48441.1 - 0.0019 18.2 0.2 0.0027 17.8 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 KFH48441.1 - 0.01 15.7 1.0 0.02 14.8 0.7 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Pyr_redox PF00070.22 KFH48441.1 - 0.021 15.2 0.9 0.23 11.8 0.4 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase KR PF08659.5 KFH48441.1 - 0.086 12.4 0.3 0.14 11.8 0.2 1.3 1 0 0 1 1 1 0 KR domain FAD_binding_3 PF01494.14 KFH48441.1 - 0.089 11.8 0.4 0.14 11.1 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain DUF515 PF04415.7 KFH48441.1 - 0.11 10.7 0.0 0.15 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) ThiF PF00899.16 KFH48441.1 - 0.75 9.6 2.9 1.2 9.0 0.8 2.0 2 0 0 2 2 2 0 ThiF family Y_phosphatase2 PF03162.8 KFH48442.1 - 1.9e-43 147.6 0.0 2.8e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 KFH48442.1 - 3.8e-09 36.9 0.0 5.4e-07 30.0 0.0 2.4 1 1 1 2 2 2 2 Tyrosine phosphatase family Y_phosphatase PF00102.22 KFH48442.1 - 0.015 14.6 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.15 KFH48442.1 - 0.051 13.1 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Arrestin_C PF02752.17 KFH48443.1 - 7.1e-17 61.7 0.0 1.9e-15 57.1 0.0 2.8 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KFH48443.1 - 5.3e-08 32.8 0.0 0.0051 16.6 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain DUF3680 PF12441.3 KFH48444.1 - 1.6 8.6 7.1 0.59 10.0 2.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3680) Strabismus PF06638.6 KFH48444.1 - 5.9 5.0 7.1 0.36 9.0 1.3 1.6 2 0 0 2 2 2 0 Strabismus protein Aminotran_5 PF00266.14 KFH48446.1 - 1.1e-28 100.0 0.0 1.4e-28 99.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 KFH48446.1 - 0.049 13.5 0.2 0.26 11.1 0.0 2.3 3 1 0 3 3 3 0 B12 binding domain IPK PF03770.11 KFH48447.1 - 5.7e-57 192.5 0.0 1.1e-56 191.6 0.0 1.5 1 0 0 1 1 1 1 Inositol polyphosphate kinase Fungal_trans_2 PF11951.3 KFH48448.1 - 1.5e-57 194.9 0.7 2.2e-57 194.3 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH48448.1 - 1.8e-07 30.9 16.2 3.2e-07 30.1 11.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMO-like PF00743.14 KFH48449.1 - 1.5e-32 112.5 0.0 2.1e-21 75.7 0.0 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KFH48449.1 - 1.3e-16 61.3 0.0 2.5e-15 57.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFH48449.1 - 7.7e-12 44.7 0.0 6.3e-09 35.2 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KFH48449.1 - 5.8e-05 22.9 0.2 0.012 15.3 0.1 3.1 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KFH48449.1 - 9.4e-05 22.3 0.0 0.03 14.1 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TOBE_2 PF08402.5 KFH48449.1 - 0.00084 19.2 0.1 0.0035 17.3 0.0 2.0 2 0 0 2 2 2 1 TOBE domain NAD_binding_8 PF13450.1 KFH48449.1 - 0.00095 19.1 0.0 0.0038 17.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KFH48449.1 - 0.0057 17.0 0.1 1.2 9.6 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KFH48449.1 - 0.055 12.3 0.0 1.9 7.2 0.0 2.8 3 0 0 3 3 3 0 FAD dependent oxidoreductase Zn_clus PF00172.13 KFH48451.1 - 5.4e-09 35.8 7.2 9.5e-09 35.0 5.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFH48451.1 - 3.3e-05 22.8 0.0 9.5e-05 21.3 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain CRCB PF02537.10 KFH48453.1 - 8.3e-31 106.3 23.0 4.8e-20 71.5 5.5 3.7 4 0 0 4 4 4 3 CrcB-like protein Glycos_transf_1 PF00534.15 KFH48454.1 - 3.2e-32 111.2 0.0 1.4e-18 66.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KFH48454.1 - 5.8e-10 39.1 0.0 0.0011 18.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 KFH48454.1 - 1.6e-08 34.8 1.5 1.5e-05 25.1 0.1 3.8 3 1 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KFH48454.1 - 2.3e-08 34.3 0.8 2.3e-08 34.3 0.5 2.3 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 KFH48454.1 - 4.6e-06 26.8 0.0 8.9e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 LicD PF04991.8 KFH48455.1 - 3.2e-34 118.8 4.1 3.2e-34 118.8 2.8 2.7 2 1 0 2 2 2 1 LicD family P21-Arc PF04062.9 KFH48456.1 - 1.2e-78 262.9 0.0 1.3e-78 262.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit RdRP PF05183.7 KFH48457.1 - 3.8e-88 296.6 0.0 3.6e-85 286.8 0.0 3.5 1 1 0 1 1 1 1 RNA dependent RNA polymerase zf-UBP PF02148.14 KFH48457.1 - 0.031 14.3 0.2 0.27 11.3 0.2 2.2 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Ank_2 PF12796.2 KFH48458.1 - 3.5e-26 91.3 0.0 7.2e-15 55.1 0.0 3.0 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFH48458.1 - 1.6e-24 84.4 1.1 5e-08 32.3 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 KFH48458.1 - 1e-22 80.0 1.1 3.5e-06 27.3 0.0 5.1 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFH48458.1 - 1.7e-21 74.1 0.5 0.0003 20.7 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 KFH48458.1 - 8.8e-18 63.9 2.1 8.6e-09 35.3 0.1 5.6 1 1 4 5 5 5 3 Ankyrin repeats (many copies) TFIID_30kDa PF03540.8 KFH48459.1 - 2.5e-26 91.2 0.3 4.1e-26 90.5 0.2 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit NACHT PF05729.7 KFH48460.1 - 1.3e-06 28.1 0.0 4.1e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KFH48460.1 - 1.5e-06 28.4 0.7 4.3e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain TPR_11 PF13414.1 KFH48460.1 - 1.7e-06 27.5 5.4 0.0039 16.8 0.2 4.2 3 0 0 3 3 3 2 TPR repeat TPR_16 PF13432.1 KFH48460.1 - 4.5e-06 27.1 0.8 0.12 13.1 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat AAA_16 PF13191.1 KFH48460.1 - 2e-05 24.6 0.5 0.0012 18.9 0.0 3.4 3 0 0 3 3 3 1 AAA ATPase domain TPR_19 PF14559.1 KFH48460.1 - 6.6e-05 23.1 3.0 0.33 11.3 0.0 4.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFH48460.1 - 0.017 15.7 10.3 11 7.0 0.3 6.0 3 2 2 5 5 5 0 Tetratricopeptide repeat AAA_19 PF13245.1 KFH48460.1 - 0.068 12.9 0.0 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Torsin PF06309.6 KFH48460.1 - 0.11 12.4 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Torsin TPR_12 PF13424.1 KFH48460.1 - 2.3 8.2 13.4 0.14 12.1 0.9 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Zn_clus PF00172.13 KFH48461.1 - 3.1e-08 33.3 10.8 4.6e-08 32.8 7.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 KFH48462.1 - 2.6e-52 177.5 0.1 7.7e-37 126.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFH48462.1 - 8.4e-22 77.4 0.0 8.6e-20 70.8 0.0 3.1 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH48462.1 - 1.2e-05 24.4 0.0 3.1e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KFH48462.1 - 0.0078 15.9 0.1 0.022 14.4 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family CTP_transf_2 PF01467.21 KFH48464.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.6 2 0 0 2 2 2 0 Cytidylyltransferase MFS_1 PF07690.11 KFH48465.1 - 4.5e-16 58.4 38.1 3.7e-15 55.4 23.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH48465.1 - 0.00036 19.2 10.3 0.00036 19.2 7.1 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter Glyco_hydro_12 PF01670.11 KFH48466.1 - 8.6e-25 87.3 0.2 1.2e-24 86.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Glyco_hydro_31 PF01055.21 KFH48467.1 - 1.4e-87 294.3 0.0 1.7e-87 294.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KFH48467.1 - 2.6e-14 52.7 0.4 9e-14 51.0 0.0 2.1 2 0 0 2 2 2 1 Galactose mutarotase-like Cyclase PF04199.8 KFH48468.1 - 1.4e-12 47.6 0.5 2.6e-12 46.7 0.2 1.6 1 1 1 2 2 2 1 Putative cyclase Striatin PF08232.7 KFH48469.1 - 1.6e-35 122.3 4.0 3e-35 121.4 2.8 1.5 1 0 0 1 1 1 1 Striatin family WD40 PF00400.27 KFH48469.1 - 1.1e-31 107.5 14.9 8.6e-08 31.7 0.1 7.2 6 1 0 6 6 6 5 WD domain, G-beta repeat XPA_C PF05181.7 KFH48471.1 - 1.7e-29 101.1 2.4 3.6e-29 100.1 1.6 1.6 1 0 0 1 1 1 1 XPA protein C-terminus ArfGap PF01412.13 KFH48471.1 - 0.0079 15.9 1.3 0.0079 15.9 0.9 2.6 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf XPA_N PF01286.13 KFH48471.1 - 0.0091 15.6 5.9 0.0091 15.6 4.1 2.0 2 0 0 2 2 2 1 XPA protein N-terminal FRG1 PF06229.7 KFH48471.1 - 0.018 14.4 0.9 0.04 13.3 0.6 1.6 1 0 0 1 1 1 0 FRG1-like family zf-C3HC4_3 PF13920.1 KFH48471.1 - 0.37 10.5 6.9 0.13 11.9 2.6 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Beta-lactamase PF00144.19 KFH48472.1 - 5.8e-52 176.7 1.9 7.8e-52 176.3 1.3 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 KFH48472.1 - 0.12 11.5 0.0 0.34 10.1 0.0 1.7 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase QueF PF14489.1 KFH48472.1 - 0.15 12.0 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 QueF-like protein Gin PF10764.4 KFH48473.1 - 0.074 12.7 0.5 0.11 12.2 0.3 1.2 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin zf-met2 PF12907.2 KFH48473.1 - 0.1 12.5 0.5 0.17 11.8 0.3 1.4 1 0 0 1 1 1 0 Zinc-binding SnoaL_2 PF12680.2 KFH48475.1 - 0.12 12.7 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain BRCT PF00533.21 KFH48476.1 - 7.9e-39 131.6 0.0 3.6e-13 49.4 0.0 4.4 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KFH48476.1 - 1.2e-38 130.7 0.7 1.3e-16 60.2 0.1 3.6 3 0 0 3 3 3 3 twin BRCT domain MFS_1 PF07690.11 KFH48477.1 - 1.1e-22 80.2 56.0 4.5e-16 58.5 19.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ECH PF00378.15 KFH48478.1 - 6.2e-22 77.9 0.0 7.6e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Histone PF00125.19 KFH48479.1 - 3.5e-22 78.2 0.0 4.5e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFH48479.1 - 5e-05 23.2 0.0 7.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Peptidase_C48 PF02902.14 KFH48480.1 - 0.18 11.3 0.2 0.33 10.5 0.1 1.4 1 0 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain APH PF01636.18 KFH48481.1 - 0.00038 20.2 0.1 0.0022 17.7 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Macoilin PF09726.4 KFH48482.1 - 3.3 5.8 7.2 4 5.5 5.0 1.1 1 0 0 1 1 1 0 Transmembrane protein HET PF06985.6 KFH48483.1 - 8.9e-27 93.9 1.2 1.6e-22 80.1 0.6 2.4 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 KFH48483.1 - 2.6e-17 62.9 0.1 4.6e-17 62.1 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFH48483.1 - 2.7e-15 56.0 3.3 5.4e-11 42.3 0.2 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KFH48483.1 - 1.6e-14 52.8 0.9 0.00044 19.9 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 KFH48483.1 - 8.3e-09 34.8 0.1 0.021 15.0 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KFH48483.1 - 8.4e-08 32.5 0.4 1.3e-05 25.5 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) OmdA PF13376.1 KFH48486.1 - 2.9e-16 58.8 0.2 3.5e-16 58.6 0.2 1.1 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated bZIP_1 PF00170.16 KFH48487.1 - 8.8e-10 38.4 9.9 1.8e-09 37.4 6.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFH48487.1 - 0.00021 21.0 9.3 0.00021 21.0 6.5 2.0 2 0 0 2 2 2 1 Basic region leucine zipper DUF904 PF06005.7 KFH48487.1 - 0.035 14.4 0.2 0.035 14.4 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF904) DivIC PF04977.10 KFH48487.1 - 0.48 9.9 5.8 0.6 9.6 0.6 2.7 2 0 0 2 2 2 0 Septum formation initiator COesterase PF00135.23 KFH48488.1 - 2.6e-95 320.1 0.0 3.4e-95 319.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFH48488.1 - 3e-05 23.6 0.1 0.0002 21.0 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF916 PF06030.7 KFH48488.1 - 0.19 11.5 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) DUF3666 PF12408.3 KFH48488.1 - 0.21 10.6 0.4 1.9 7.6 0.1 2.3 2 0 0 2 2 2 0 Ribose-5-phosphate isomerase Steroid_dh PF02544.11 KFH48489.1 - 1.2e-19 70.5 0.1 9.6e-19 67.6 0.1 2.2 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 KFH48489.1 - 0.00012 21.4 1.4 0.00021 20.7 0.1 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) ADH_zinc_N PF00107.21 KFH48490.1 - 4.3e-21 74.8 0.2 8.5e-21 73.8 0.1 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFH48490.1 - 8.5e-18 65.4 0.0 1.5e-17 64.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFH48490.1 - 1.3e-05 24.8 0.0 2.8e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AMP-binding PF00501.23 KFH48491.1 - 0 2148.7 1.7 6.4e-85 285.0 0.0 8.2 8 0 0 8 8 8 8 AMP-binding enzyme Condensation PF00668.15 KFH48491.1 - 0 1513.9 7.2 8.9e-61 205.3 0.1 9.3 9 0 0 9 9 9 9 Condensation domain HxxPF_rpt PF13745.1 KFH48491.1 - 4.7e-153 497.9 32.4 5.1e-22 77.9 0.0 9.0 9 0 0 9 9 7 7 HxxPF-repeated domain PP-binding PF00550.20 KFH48491.1 - 3.4e-97 318.7 16.1 4.4e-12 46.0 0.0 9.4 9 0 0 9 9 8 8 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KFH48491.1 - 3.1e-71 236.2 19.2 7.4e-11 42.8 0.0 12.1 11 0 0 11 11 11 11 AMP-binding enzyme C-terminal domain Methyltransf_23 PF13489.1 KFH48491.1 - 2.2e-15 56.7 0.0 0.0037 17.0 0.0 7.0 7 1 0 7 7 7 4 Methyltransferase domain Methyltransf_18 PF12847.2 KFH48491.1 - 1.7e-14 54.3 0.1 0.00097 19.7 0.0 5.3 5 0 0 5 5 5 3 Methyltransferase domain Methyltransf_31 PF13847.1 KFH48491.1 - 2.5e-12 46.6 0.0 0.0044 16.6 0.0 3.7 3 0 0 3 3 3 3 Methyltransferase domain DUF547 PF04784.9 KFH48491.1 - 0.00019 21.2 0.0 11 5.9 0.0 5.3 5 0 0 5 5 4 0 Protein of unknown function, DUF547 DUF4115 PF13464.1 KFH48491.1 - 0.0018 17.9 0.0 1.5 8.4 0.0 4.5 5 0 0 5 5 4 1 Domain of unknown function (DUF4115) Transferase PF02458.10 KFH48491.1 - 0.037 12.4 0.0 4.8 5.5 0.0 4.2 5 0 0 5 5 5 0 Transferase family DUF2183 PF09949.4 KFH48491.1 - 0.15 12.0 0.0 7 6.6 0.0 3.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) ASCH PF04266.9 KFH48491.1 - 0.35 11.2 0.2 3.8e+02 1.5 0.0 5.2 5 0 0 5 5 4 0 ASCH domain DUF2400 PF09674.5 KFH48491.1 - 0.5 10.0 0.1 35 3.9 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2400) Methyltransf_16 PF10294.4 KFH48491.1 - 1 8.7 0.0 11 5.4 0.0 2.3 2 0 0 2 2 2 0 Putative methyltransferase MdoG PF04349.7 KFH48491.1 - 1.3 7.1 0.0 2.2 6.4 0.0 1.2 1 0 0 1 1 1 0 Periplasmic glucan biosynthesis protein, MdoG Viral_P18 PF04521.8 KFH48491.1 - 5 6.5 7.4 1.7e+02 1.6 0.0 5.7 8 0 0 8 8 8 0 ssRNA positive strand viral 18kD cysteine rich protein Methyltrn_RNA_3 PF02598.12 KFH48491.1 - 5.3 6.3 0.0 86 2.3 0.0 2.3 2 0 0 2 2 2 0 Putative RNA methyltransferase SNF2_N PF00176.18 KFH48492.1 - 2.5e-69 233.3 0.0 3.4e-69 232.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 KFH48492.1 - 2e-25 88.7 0.0 3.8e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 KFH48492.1 - 6.6e-14 51.5 0.0 1.6e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 KFH48492.1 - 1.4e-06 28.2 7.9 2.6e-06 27.3 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFH48492.1 - 0.00011 21.8 5.7 0.00018 21.1 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 KFH48492.1 - 0.0008 19.2 0.0 0.002 17.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 KFH48492.1 - 0.00092 18.8 7.2 0.0017 17.9 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFH48492.1 - 0.0034 17.1 7.6 0.0065 16.2 5.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KFH48492.1 - 0.017 14.8 6.2 0.042 13.5 4.3 1.7 1 1 0 1 1 1 0 zinc-RING finger domain Peptidase_M1 PF01433.15 KFH48493.1 - 8.2e-133 443.2 0.7 1.1e-132 442.8 0.5 1.1 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KFH48493.1 - 7.7e-70 235.6 0.0 1.1e-69 235.1 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KFH48493.1 - 4.6e-21 75.1 0.8 4.6e-21 75.1 0.5 2.4 1 1 1 2 2 2 1 Peptidase MA superfamily DUF45 PF01863.12 KFH48493.1 - 0.024 14.4 0.1 0.12 12.1 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function DUF45 Mito_carr PF00153.22 KFH48494.1 - 6e-48 160.5 7.3 2.3e-18 65.6 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.11 KFH48495.1 - 4.5e-33 114.4 28.8 4.5e-33 114.4 20.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Na_Ca_ex PF01699.19 KFH48496.1 - 3.7e-30 104.3 33.6 8.5e-19 67.5 6.5 3.9 4 0 0 4 4 4 2 Sodium/calcium exchanger protein DUF307 PF03733.8 KFH48496.1 - 1.1e-13 51.3 12.3 1.1e-13 51.3 8.5 3.6 2 0 0 2 2 2 1 Domain of unknown function (DUF307) SPO22 PF08631.5 KFH48498.1 - 5e-50 170.1 0.3 4.3e-49 167.0 0.1 2.5 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.1 KFH48498.1 - 0.0017 18.2 10.5 0.063 13.2 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat BC10 PF06726.7 KFH48499.1 - 6e-18 64.6 10.9 8.5e-18 64.1 7.6 1.2 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Ank_2 PF12796.2 KFH48500.1 - 6.1e-19 68.1 0.6 1.6e-10 41.2 0.1 3.8 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFH48500.1 - 1.6e-18 65.4 1.5 1.4e-09 37.3 0.2 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 KFH48500.1 - 5.7e-16 58.5 6.0 0.0001 22.6 0.0 6.5 4 2 3 7 7 7 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFH48500.1 - 1e-13 51.0 11.8 5.9e-09 35.8 0.4 5.1 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFH48500.1 - 8.1e-10 37.9 7.5 1.5e-05 24.7 0.1 6.8 8 1 0 8 8 8 1 Ankyrin repeat Y_phosphatase PF00102.22 KFH48501.1 - 3.4e-60 203.3 0.2 9.5e-34 116.7 0.0 3.2 3 0 0 3 3 3 3 Protein-tyrosine phosphatase Rhodanese PF00581.15 KFH48501.1 - 1.4e-12 47.9 0.0 3.7e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 KFH48501.1 - 0.0031 17.8 0.0 0.013 15.7 0.0 2.1 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 KFH48501.1 - 0.059 12.9 0.4 0.13 11.8 0.3 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain KGG PF10685.4 KFH48502.1 - 4.1e-27 93.5 20.5 2.5e-12 46.3 2.0 3.1 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif Bax1-I PF01027.15 KFH48503.1 - 0.032 13.8 1.2 0.038 13.5 0.8 1.0 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 CD47 PF04549.9 KFH48503.1 - 0.095 12.7 0.4 0.11 12.4 0.2 1.2 1 0 0 1 1 1 0 CD47 transmembrane region CstA PF02554.9 KFH48503.1 - 0.12 10.9 2.0 0.12 10.9 1.4 1.0 1 0 0 1 1 1 0 Carbon starvation protein CstA Cellulase PF00150.13 KFH48504.1 - 8.1e-52 176.1 4.2 9.4e-52 175.9 2.9 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Fungal_trans PF04082.13 KFH48505.1 - 1.3e-15 56.9 0.4 2.2e-15 56.2 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KFH48505.1 - 2.1e-08 34.0 12.6 0.00093 19.4 1.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFH48505.1 - 1.3e-06 28.3 6.4 1.3e-06 28.3 4.4 2.9 3 0 0 3 3 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFH48505.1 - 0.00037 20.6 14.0 0.061 13.6 1.9 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 KFH48505.1 - 0.078 13.2 1.3 0.23 11.7 0.9 1.9 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFH48505.1 - 0.098 12.8 4.2 0.42 10.8 0.4 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Suf PF05843.9 KFH48505.1 - 0.62 9.7 8.8 0.015 15.0 1.3 1.7 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) BAF1_ABF1 PF04684.8 KFH48505.1 - 0.62 8.8 19.6 1.2 7.8 13.6 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Serinc PF03348.10 KFH48505.1 - 1.1 7.9 1.2 1.6 7.3 0.8 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) FimP PF09766.4 KFH48505.1 - 6.4 5.7 16.0 10 5.0 11.1 1.2 1 0 0 1 1 1 0 Fms-interacting protein zf-C2H2_6 PF13912.1 KFH48505.1 - 7.9 6.5 7.8 2.7 8.0 0.7 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Peptidase_S9 PF00326.16 KFH48506.1 - 1e-15 57.5 0.0 1.4e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFH48506.1 - 3.5e-10 39.8 0.0 4.4e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KFH48506.1 - 4.3e-10 39.5 0.0 6.6e-10 38.9 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 KFH48506.1 - 1.3e-06 27.9 0.0 2.3e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 KFH48506.1 - 0.00035 20.5 0.1 0.0034 17.3 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 KFH48506.1 - 0.0021 17.3 0.2 0.11 11.6 0.1 2.5 2 1 0 2 2 2 1 Secretory lipase DUF2048 PF09752.4 KFH48506.1 - 0.0035 16.2 0.0 0.0049 15.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) FSH1 PF03959.8 KFH48506.1 - 0.01 15.2 0.0 0.02 14.3 0.0 1.3 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.5 KFH48506.1 - 0.047 13.5 0.0 0.079 12.8 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein DUF1989 PF09347.5 KFH48507.1 - 1.1e-53 181.1 0.0 1.4e-53 180.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) RTA1 PF04479.8 KFH48508.1 - 1.3e-07 31.3 12.2 4.8e-06 26.2 8.4 2.8 1 1 0 1 1 1 1 RTA1 like protein Alk_phosphatase PF00245.15 KFH48509.1 - 1.2e-105 353.6 0.0 1.5e-105 353.3 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 KFH48509.1 - 0.00096 18.6 0.1 0.0022 17.4 0.1 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily RskA PF10099.4 KFH48509.1 - 0.029 14.1 0.2 0.071 12.8 0.1 1.7 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF3357 PF11837.3 KFH48509.1 - 0.038 13.8 0.0 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DUF1294 PF06961.8 KFH48509.1 - 0.14 12.1 0.7 0.45 10.4 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1294) DUF4246 PF14033.1 KFH48510.1 - 1.6e-174 581.2 6.0 2.1e-174 580.8 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 KFH48510.1 - 0.005 17.1 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase DUF2271 PF10029.4 KFH48510.1 - 0.0065 15.9 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 Predicted periplasmic protein (DUF2271) Ribosomal_S19 PF00203.16 KFH48512.1 - 9.7e-21 73.1 0.0 1.2e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 ABC_membrane PF00664.18 KFH48513.1 - 4.1e-79 265.8 35.1 1.3e-40 139.5 9.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFH48513.1 - 1.9e-68 228.9 0.0 9e-33 113.4 0.0 2.9 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.14 KFH48513.1 - 2.4e-12 46.5 5.4 2.2e-05 23.8 0.0 4.1 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFH48513.1 - 5.6e-12 46.2 0.0 0.014 15.3 0.0 4.3 4 0 0 4 4 4 4 AAA domain AAA_16 PF13191.1 KFH48513.1 - 9.5e-11 42.0 3.5 7.1e-07 29.3 0.1 3.1 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.4 KFH48513.1 - 5.2e-09 35.1 1.8 0.0055 15.3 0.0 3.9 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 KFH48513.1 - 7e-08 31.8 0.1 0.0045 16.4 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KFH48513.1 - 5.1e-07 29.0 0.0 0.031 13.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 KFH48513.1 - 3.2e-06 27.9 0.0 0.032 15.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KFH48513.1 - 5.6e-06 25.8 0.1 0.085 12.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KFH48513.1 - 7.6e-06 26.1 2.3 0.019 15.0 0.1 3.8 2 2 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 KFH48513.1 - 4.9e-05 23.1 0.4 0.68 9.8 0.1 3.8 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 KFH48513.1 - 0.00012 21.8 0.1 0.44 10.2 0.0 3.3 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 KFH48513.1 - 0.0003 20.4 0.6 1 8.8 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA PF00004.24 KFH48513.1 - 0.0006 20.0 2.4 1.1 9.5 0.1 4.1 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KFH48513.1 - 0.00066 19.6 0.0 1 9.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KFH48513.1 - 0.0013 18.6 0.1 0.31 10.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KFH48513.1 - 0.0035 17.6 0.0 2.6 8.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KFH48513.1 - 0.0076 15.7 0.1 0.62 9.4 0.0 2.5 2 1 0 2 2 2 1 AAA-like domain AAA_14 PF13173.1 KFH48513.1 - 0.011 15.6 0.0 9.3 6.1 0.0 3.2 4 0 0 4 4 3 0 AAA domain Rad17 PF03215.10 KFH48513.1 - 0.012 14.3 0.1 1.8 7.1 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 KFH48513.1 - 0.015 15.4 0.0 4.8 7.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase MobB PF03205.9 KFH48513.1 - 0.018 14.7 0.2 0.93 9.1 0.0 3.0 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.15 KFH48513.1 - 0.033 12.8 0.0 5.8 5.4 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit NACHT PF05729.7 KFH48513.1 - 0.041 13.5 0.1 9.8 5.7 0.0 3.1 3 0 0 3 3 2 0 NACHT domain ATP-synt_ab PF00006.20 KFH48513.1 - 0.045 13.2 0.9 1 8.7 0.0 2.7 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.18 KFH48513.1 - 0.048 13.6 0.0 4.3 7.3 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.12 KFH48513.1 - 0.072 12.8 0.0 4.7 6.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_23 PF13476.1 KFH48513.1 - 0.22 11.8 0.5 23 5.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain ApbA_C PF08546.6 KFH48514.1 - 1.7e-31 108.8 0.0 2.7e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KFH48514.1 - 6.3e-24 84.1 0.0 8.9e-24 83.6 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 KFH48514.1 - 0.0075 16.3 0.9 0.018 15.1 0.1 2.0 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 KFH48514.1 - 0.075 11.9 0.2 0.11 11.3 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Saccharop_dh PF03435.13 KFH48514.1 - 0.085 11.8 0.1 0.14 11.1 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Pyr_redox PF00070.22 KFH48514.1 - 0.12 12.7 0.1 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Chorismate_synt PF01264.16 KFH48515.1 - 1.2e-129 431.7 0.0 1.5e-129 431.4 0.0 1.1 1 0 0 1 1 1 1 Chorismate synthase EpuA PF11772.3 KFH48516.1 - 0.92 8.9 5.1 1.9 7.9 3.6 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta AAA PF00004.24 KFH48518.1 - 1.6e-08 34.8 0.8 7.3e-07 29.4 1.5 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KFH48518.1 - 4.2e-06 27.5 0.0 1.2e-05 26.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFH48518.1 - 0.00011 22.2 0.0 0.00035 20.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 KFH48518.1 - 0.00028 21.1 0.0 0.0009 19.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KFH48518.1 - 0.00042 20.4 0.1 0.0013 18.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 KFH48518.1 - 0.0026 16.5 0.0 0.004 15.9 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_28 PF13521.1 KFH48518.1 - 0.0027 17.6 0.1 0.0071 16.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFH48518.1 - 0.016 14.3 0.0 0.034 13.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 KFH48518.1 - 0.029 14.1 0.1 0.093 12.4 0.0 1.8 2 0 0 2 2 2 0 Part of AAA domain AAA_33 PF13671.1 KFH48518.1 - 0.045 13.6 0.0 0.097 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KFH48518.1 - 0.058 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Arch_ATPase PF01637.13 KFH48518.1 - 0.086 12.5 0.1 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Rad17 PF03215.10 KFH48518.1 - 0.1 11.2 0.1 0.71 8.4 0.0 2.3 4 0 0 4 4 4 0 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 KFH48518.1 - 0.2 11.5 0.0 0.51 10.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain Ufd2P_core PF10408.4 KFH48519.1 - 1.3e-186 621.5 5.6 1.7e-186 621.2 3.9 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 KFH48519.1 - 1.1e-26 92.6 0.5 4.4e-26 90.6 0.3 2.2 2 0 0 2 2 2 1 U-box domain DUF2361 PF10153.4 KFH48519.1 - 0.096 12.8 6.5 0.16 12.1 0.3 2.6 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2361) CCDC-167 PF15188.1 KFH48519.1 - 0.24 11.3 9.6 0.056 13.3 0.9 3.3 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 DUF566 PF04484.7 KFH48519.1 - 3.2 7.1 12.7 5.7 6.3 8.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) Abhydrolase_3 PF07859.8 KFH48520.1 - 9.9e-35 120.0 0.0 1.2e-22 80.4 0.0 3.0 2 1 1 3 3 3 2 alpha/beta hydrolase fold DUF2424 PF10340.4 KFH48520.1 - 0.066 11.8 0.0 0.099 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Glyco_hydro_35 PF01301.14 KFH48521.1 - 1.5e-77 261.0 0.4 9.4e-77 258.4 0.3 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 KFH48521.1 - 1.6e-65 219.8 1.0 6.7e-65 217.8 0.2 2.1 2 0 0 2 2 2 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 KFH48521.1 - 8e-40 135.5 6.7 2.5e-20 72.8 0.5 2.9 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 KFH48521.1 - 5.7e-20 70.4 0.0 1.3e-19 69.3 0.0 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cellulase PF00150.13 KFH48521.1 - 4e-08 32.7 0.0 8.7e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 KFH48521.1 - 4.2e-06 26.1 0.1 0.00031 19.9 0.1 2.5 1 1 1 2 2 2 1 Beta-galactosidase DUF2407_C PF13373.1 KFH48522.1 - 1e-31 109.6 0.0 1.3e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 KFH48522.1 - 6.8e-22 77.4 0.0 1e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 KFH48522.1 - 0.0044 16.3 0.0 0.0073 15.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF3343 PF11823.3 KFH48522.1 - 0.031 13.5 0.1 0.063 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) CN_hydrolase PF00795.17 KFH48523.1 - 1.6e-22 79.7 0.0 2.4e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase FAD_binding_3 PF01494.14 KFH48524.1 - 2.7e-56 191.1 0.0 3.2e-56 190.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 KFH48524.1 - 0.00059 19.0 0.0 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase MFS_1 PF07690.11 KFH48526.1 - 1e-38 132.9 29.2 1e-38 132.9 20.2 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH48526.1 - 3.3e-07 29.2 9.8 3.3e-07 29.2 6.8 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter ATP-synt_8 PF00895.15 KFH48526.1 - 0.11 12.7 2.3 1.6 9.0 0.5 3.3 3 0 0 3 3 3 0 ATP synthase protein 8 Oxysterol_BP PF01237.13 KFH48528.1 - 8.8e-59 198.7 0.0 1.2e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Bombolitin PF08096.6 KFH48528.1 - 0.16 12.0 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Bombolitin family TT_ORF1 PF02956.9 KFH48529.1 - 2.9 6.2 7.3 3.1 6.1 5.0 1.1 1 0 0 1 1 1 0 TT viral orf 1 COX7C PF02935.11 KFH48530.1 - 3.4e-14 52.3 0.2 5.2e-14 51.7 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc DUF4396 PF14342.1 KFH48531.1 - 6.9e-44 149.3 0.3 8.5e-44 149.0 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) DUF606 PF04657.8 KFH48531.1 - 0.056 13.5 2.0 0.054 13.5 0.5 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF606 DUF2416 PF10315.4 KFH48532.1 - 0.076 13.2 0.3 0.16 12.2 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2416) LSM PF01423.17 KFH48533.1 - 7.1e-18 63.9 0.0 8.9e-18 63.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain GTP_EFTU PF00009.22 KFH48534.1 - 1.7e-21 76.4 0.0 3.8e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KFH48534.1 - 2.8e-14 53.0 1.0 7.8e-14 51.6 0.0 2.2 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KFH48534.1 - 4.6e-08 33.0 0.8 1.4e-07 31.5 0.6 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 KFH48534.1 - 0.00091 19.7 0.0 0.071 13.6 0.0 2.9 2 1 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 KFH48534.1 - 0.0049 16.8 0.0 0.013 15.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KFH48534.1 - 0.1 12.4 0.2 0.28 11.0 0.0 1.8 2 0 0 2 2 2 0 Dynamin family ATG27 PF09451.5 KFH48535.1 - 2.5e-69 233.4 0.0 4e-69 232.8 0.0 1.3 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 KFH48535.1 - 0.15 11.8 0.0 22 4.7 0.0 2.7 3 0 0 3 3 3 0 Cation-independent mannose-6-phosphate receptor repeat CobT PF06213.7 KFH48535.1 - 9 5.3 11.5 16 4.5 8.0 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ald_Xan_dh_C2 PF02738.13 KFH48536.1 - 9.9e-194 644.6 0.1 1.4e-193 644.1 0.1 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 KFH48536.1 - 2.7e-49 166.8 0.0 5.2e-49 165.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.17 KFH48536.1 - 2.9e-33 114.2 0.4 6.8e-33 113.0 0.3 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.12 KFH48536.1 - 1.5e-29 101.9 1.0 4.2e-29 100.5 0.1 2.3 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 KFH48536.1 - 2.1e-28 98.0 0.1 4.5e-28 96.9 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 KFH48536.1 - 6.5e-08 32.2 0.6 2.3e-07 30.4 0.1 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF218 PF02698.12 KFH48536.1 - 0.06 12.8 0.1 0.21 11.0 0.0 1.9 2 0 0 2 2 2 0 DUF218 domain UPRTase PF14681.1 KFH48537.1 - 8.1e-71 237.4 0.0 9.2e-71 237.3 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KFH48537.1 - 1.3e-05 24.9 0.1 3.7e-05 23.4 0.1 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain TMP-TENI PF02581.12 KFH48537.1 - 0.039 13.0 0.4 1.2 8.2 0.1 2.3 2 1 0 2 2 2 0 Thiamine monophosphate synthase/TENI MRP-S25 PF13741.1 KFH48538.1 - 2.9e-69 233.0 7.7 5.1e-67 225.7 5.3 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 Fungal_trans PF04082.13 KFH48539.1 - 2.1e-25 89.1 0.6 1.2e-23 83.2 0.0 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH48539.1 - 1.4e-07 31.2 10.1 2.2e-07 30.6 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GFA PF04828.9 KFH48540.1 - 2.7e-20 72.0 2.1 7.3e-09 35.4 0.3 3.4 2 1 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme PHO4 PF01384.15 KFH48541.1 - 2e-109 365.2 12.9 2.4e-109 364.9 9.0 1.1 1 0 0 1 1 1 1 Phosphate transporter family Spo7 PF03907.8 KFH48541.1 - 0.13 11.8 0.1 0.27 10.8 0.1 1.4 1 0 0 1 1 1 0 Spo7-like protein HNH_2 PF13391.1 KFH48542.1 - 4.1e-08 32.8 0.0 8.4e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease zf-C2H2 PF00096.21 KFH48543.1 - 5e-07 29.6 14.0 0.0059 16.8 3.7 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type Motilin_ghrelin PF04644.7 KFH48543.1 - 0.011 15.5 0.6 0.032 14.0 0.4 1.8 1 0 0 1 1 1 0 Motilin/ghrelin DUF2962 PF11176.3 KFH48543.1 - 0.02 14.4 0.5 0.02 14.4 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2962) zf-H2C2_2 PF13465.1 KFH48543.1 - 0.026 14.8 1.6 0.026 14.8 1.1 3.8 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFH48543.1 - 0.027 14.7 4.7 0.027 14.7 3.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger DUF3505 PF12013.3 KFH48543.1 - 0.49 10.6 10.2 2.5 8.3 7.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3505) Ricin_B_lectin PF00652.17 KFH48544.1 - 7.8e-06 25.9 0.0 2.1e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 KFH48544.1 - 0.1 12.9 0.0 0.4 11.0 0.0 2.0 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like DAO PF01266.19 KFH48545.1 - 3.9e-19 68.7 2.1 5.1e-19 68.3 1.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFH48545.1 - 0.04 13.7 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFH48545.1 - 0.049 13.6 0.0 0.15 12.0 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KFH48545.1 - 0.063 13.6 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ras PF00071.17 KFH48546.1 - 5e-11 42.2 0.0 8e-11 41.5 0.0 1.4 1 1 0 1 1 1 1 Ras family Chs3p PF12271.3 KFH48547.1 - 2.3e-134 447.0 12.9 2.6e-134 446.7 9.0 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit ADH_zinc_N_2 PF13602.1 KFH48548.1 - 6.4e-24 85.2 0.1 1.2e-23 84.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KFH48548.1 - 1e-14 54.2 1.0 1.6e-14 53.6 0.2 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase HATPase_c_3 PF13589.1 KFH48549.1 - 2.1e-16 59.8 0.0 4.1e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 KFH48549.1 - 4.1e-09 36.1 0.0 2.1e-08 33.8 0.0 2.1 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 KFH48549.1 - 6.7e-05 22.5 0.1 0.00022 20.9 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Gcd10p PF04189.8 KFH48551.1 - 1.4e-72 244.3 0.0 1.9e-72 243.9 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family zf-C2H2_4 PF13894.1 KFH48553.1 - 0.17 12.2 12.6 1.4 9.3 1.8 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KFH48553.1 - 5 7.6 10.3 0.33 11.3 1.4 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type Sarcoglycan_2 PF05510.8 KFH48554.1 - 0.14 10.4 0.0 0.2 9.9 0.0 1.2 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Pho88 PF10032.4 KFH48555.1 - 3e-80 267.9 0.1 3.3e-80 267.8 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF544 PF04424.8 KFH48556.1 - 5.3e-14 52.0 0.0 9.7e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF544) Abhydrolase_2 PF02230.11 KFH48557.1 - 6.3e-25 87.8 0.0 1e-23 83.9 0.0 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KFH48557.1 - 1.8e-08 34.5 4.8 2.2e-06 27.7 3.3 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH48557.1 - 3.2e-08 33.4 0.0 4.8e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFH48557.1 - 0.00025 20.3 0.0 0.028 13.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 KFH48557.1 - 0.019 14.5 0.0 0.36 10.3 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold ATP13 PF12921.2 KFH48558.1 - 1.6e-18 66.3 0.0 3.2e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ATPase expression Clathrin PF00637.15 KFH48559.1 - 2.1e-21 76.0 4.0 4.4e-20 71.7 0.3 2.7 3 0 0 3 3 3 1 Region in Clathrin and VPS VPS11_C PF12451.3 KFH48559.1 - 1.8e-14 53.2 0.1 3.7e-14 52.2 0.1 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-RING_5 PF14634.1 KFH48559.1 - 0.0028 17.3 1.9 0.0053 16.4 1.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KFH48559.1 - 0.014 15.1 2.9 0.032 14.0 2.0 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.20 KFH48559.1 - 0.04 13.5 1.6 0.083 12.5 1.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Vps8 PF12816.2 KFH48559.1 - 0.061 12.5 0.0 0.14 11.3 0.0 1.6 1 0 0 1 1 1 0 Golgi CORVET complex core vacuolar protein 8 zf-Apc11 PF12861.2 KFH48559.1 - 0.29 10.9 1.3 0.72 9.7 0.9 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DnaJ_CXXCXGXG PF00684.14 KFH48559.1 - 1.5 8.8 4.7 3 7.9 3.2 1.4 1 0 0 1 1 1 0 DnaJ central domain Ank PF00023.25 KFH48560.1 - 0.00036 20.2 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KFH48560.1 - 0.0018 18.5 0.0 0.0036 17.6 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KFH48560.1 - 0.017 15.3 0.0 7 7.2 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.2 KFH48561.1 - 9.5e-09 35.4 0.0 1.6e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFH48561.1 - 1.6e-08 33.9 0.1 0.00011 21.8 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KFH48561.1 - 6.6e-07 29.6 0.4 4.7e-06 26.9 0.2 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFH48561.1 - 0.00024 21.0 0.1 0.15 12.3 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 KFH48561.1 - 0.00059 20.0 0.2 0.0043 17.2 0.1 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) LRR_4 PF12799.2 KFH48562.1 - 1.7e-23 81.7 34.7 1.7e-07 30.6 3.2 7.9 5 1 4 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFH48562.1 - 5.8e-19 67.5 31.4 1.8e-06 27.5 0.5 6.7 5 1 2 7 7 7 6 Leucine rich repeat LRR_1 PF00560.28 KFH48562.1 - 3.4e-08 32.4 28.5 1.3 9.3 0.0 11.4 10 1 1 11 11 11 4 Leucine Rich Repeat LRR_7 PF13504.1 KFH48562.1 - 1.6e-05 24.3 28.8 13 6.5 0.2 11.3 10 2 1 11 11 11 3 Leucine rich repeat LRR_6 PF13516.1 KFH48562.1 - 0.00012 21.7 22.2 0.065 13.3 0.1 8.8 10 1 1 11 11 11 1 Leucine Rich repeat LRR_9 PF14580.1 KFH48562.1 - 0.00074 19.1 10.2 0.2 11.1 0.4 4.1 2 1 2 4 4 4 3 Leucine-rich repeat Abhydrolase_6 PF12697.2 KFH48563.1 - 6.7e-26 91.5 0.0 1.3e-25 90.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFH48563.1 - 6.6e-12 45.4 0.0 1.5e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.9 KFH48563.1 - 6e-07 28.2 0.0 9.2e-07 27.6 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_5 PF12695.2 KFH48563.1 - 1.2e-05 25.1 0.0 2.6e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KFH48563.1 - 0.00019 20.9 0.0 0.00034 20.1 0.0 1.4 1 0 0 1 1 1 1 Putative esterase EthD PF07110.6 KFH48563.1 - 0.00055 20.8 0.1 1.1 10.1 0.0 2.7 2 0 0 2 2 2 2 EthD domain BPL_LplA_LipB PF03099.14 KFH48565.1 - 2.7e-18 66.2 0.0 4.4e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family MFS_1 PF07690.11 KFH48566.1 - 2.7e-28 98.6 47.5 2.3e-22 79.1 22.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFH48567.1 - 1.2e-68 231.8 18.8 1.4e-68 231.5 13.1 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KFH48567.1 - 1.3e-21 76.7 49.5 1.3e-21 76.7 34.3 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH48567.1 - 5.9e-08 31.7 9.5 5.9e-08 31.7 6.6 3.3 3 0 0 3 3 3 2 Sugar (and other) transporter LRR_8 PF13855.1 KFH48569.1 - 0.00019 21.1 5.8 0.47 10.2 0.0 4.8 5 0 0 5 5 5 2 Leucine rich repeat LRR_4 PF12799.2 KFH48569.1 - 0.00021 20.8 4.9 4.8 6.9 0.0 4.6 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KFH48569.1 - 0.002 18.0 4.6 0.65 10.2 0.0 4.4 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.28 KFH48569.1 - 0.0076 16.1 1.9 17 5.9 0.0 4.7 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_7 PF13504.1 KFH48569.1 - 3.8 8.1 7.6 1.7e+02 3.1 0.0 5.4 5 0 0 5 5 5 0 Leucine rich repeat Fungal_trans PF04082.13 KFH48570.1 - 0.031 13.1 0.0 0.052 12.4 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain PLDc_3 PF13918.1 KFH48570.1 - 0.043 13.2 0.2 0.074 12.4 0.1 1.3 1 0 0 1 1 1 0 PLD-like domain Cyclin PF08613.6 KFH48571.1 - 2.6e-14 53.8 0.0 4.4e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KFH48571.1 - 2.2e-05 24.0 0.1 3.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain FSH1 PF03959.8 KFH48573.1 - 3.8e-36 124.5 0.0 4.8e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KFH48573.1 - 1.8e-07 31.2 0.6 6.8e-06 26.1 0.4 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH48573.1 - 0.00011 22.0 0.0 0.00018 21.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KFH48573.1 - 0.011 15.1 1.3 3.8 6.8 0.4 2.6 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Cupin_7 PF12973.2 KFH48574.1 - 1.7e-05 24.5 0.0 2.1e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 ChrR Cupin-like domain Cupin_2 PF07883.6 KFH48574.1 - 0.0067 15.9 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Cupin domain DNA_ligase_A_M PF01068.16 KFH48575.1 - 4.8e-43 146.8 0.0 1.6e-42 145.1 0.0 1.9 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KFH48575.1 - 2.2e-36 125.3 0.0 6.7e-36 123.7 0.0 1.9 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KFH48575.1 - 3.6e-16 59.3 0.1 1.6e-15 57.2 0.0 2.3 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 KFH48575.1 - 2.7e-09 37.0 0.0 4.3e-07 29.9 0.0 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.3 KFH48575.1 - 0.00097 18.8 0.0 0.0024 17.5 0.0 1.7 1 0 0 1 1 1 1 DNA ligase IV mRNA_cap_enzyme PF01331.14 KFH48575.1 - 0.0097 15.6 0.1 0.47 10.1 0.0 2.7 2 1 0 2 2 2 1 mRNA capping enzyme, catalytic domain MFS_1 PF07690.11 KFH48576.1 - 8.1e-33 113.5 27.2 8.1e-33 113.5 18.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH48576.1 - 4e-06 25.6 20.7 0.00011 20.8 14.3 2.5 1 1 1 2 2 2 2 Sugar (and other) transporter DUF3716 PF12511.3 KFH48577.1 - 4.6e-10 38.9 8.7 8.4e-10 38.1 6.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) TMEM51 PF15345.1 KFH48577.1 - 0.059 13.0 1.8 0.14 11.8 1.3 1.5 1 0 0 1 1 1 0 Transmembrane protein 51 DHquinase_I PF01487.10 KFH48578.1 - 4.2e-35 121.4 0.0 7.1e-35 120.6 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 KFH48578.1 - 3.6e-17 62.6 0.0 6.3e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase Shikimate_DH PF01488.15 KFH48578.1 - 1e-10 41.8 0.2 2.9e-10 40.3 0.1 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Shikimate_dh_N PF08501.6 KFH48578.1 - 8.6e-09 35.3 0.0 1.9e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain AAA_33 PF13671.1 KFH48578.1 - 7.3e-05 22.6 0.1 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFH48578.1 - 0.0062 17.3 0.1 0.02 15.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KFH48578.1 - 0.035 13.1 0.0 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin OCD_Mu_crystall PF02423.10 KFH48578.1 - 0.038 12.7 0.0 0.063 12.0 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family ABC_tran PF00005.22 KFH48578.1 - 0.042 14.1 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.1 KFH48578.1 - 0.059 12.7 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Homeobox_KN PF05920.6 KFH48579.1 - 5.9e-13 48.2 1.1 1.3e-12 47.1 0.8 1.6 1 0 0 1 1 1 1 Homeobox KN domain HTH_Tnp_Tc5 PF03221.11 KFH48579.1 - 1.6e-08 34.2 14.3 2.9e-05 23.7 0.3 4.9 5 1 0 5 5 5 3 Tc5 transposase DNA-binding domain Homeobox PF00046.24 KFH48579.1 - 8.4e-05 22.1 0.1 0.00027 20.5 0.1 1.9 1 0 0 1 1 1 1 Homeobox domain zf-C2H2 PF00096.21 KFH48579.1 - 0.00098 19.3 12.7 0.025 14.8 2.8 3.8 3 0 0 3 3 3 1 Zinc finger, C2H2 type HA PF03457.9 KFH48579.1 - 0.0037 17.3 4.1 0.012 15.6 0.0 3.9 5 0 0 5 5 5 1 Helicase associated domain zf-C2H2_4 PF13894.1 KFH48579.1 - 0.0079 16.4 18.3 0.048 14.0 3.1 4.1 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KFH48579.1 - 0.54 10.3 6.2 12 6.1 0.1 3.2 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) BIR PF00653.16 KFH48579.1 - 1.2 9.5 9.5 2.2 8.7 0.1 3.2 3 1 0 3 3 3 0 Inhibitor of Apoptosis domain zf-FCS PF06467.9 KFH48579.1 - 1.8 8.2 5.3 1.7 8.3 0.3 2.8 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif 2OG-Fe_Oxy_2 PF10014.4 KFH48580.1 - 2e-45 154.5 1.1 2.5e-45 154.2 0.8 1.1 1 0 0 1 1 1 1 2OG-Fe dioxygenase CoA_transf_3 PF02515.12 KFH48581.1 - 5.3e-47 159.5 0.0 7.6e-47 159.0 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III DUF1751 PF08551.5 KFH48582.1 - 1.8e-27 95.5 4.8 3.6e-27 94.5 3.3 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 KFH48582.1 - 0.0045 17.0 12.8 0.0078 16.2 8.9 1.3 1 0 0 1 1 1 1 Rhomboid family Myb_DNA-binding PF00249.26 KFH48583.1 - 1.5e-12 47.3 2.1 1.3e-09 37.9 0.0 2.6 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFH48583.1 - 8.7e-09 35.3 4.7 4.4e-05 23.5 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Suf PF05843.9 KFH48583.1 - 7 6.2 8.7 0.47 10.1 1.9 1.8 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) PHD PF00628.24 KFH48584.1 - 7.5e-12 44.7 6.4 1.8e-11 43.5 4.4 1.7 1 0 0 1 1 1 1 PHD-finger Erv26 PF04148.8 KFH48585.1 - 3.2e-83 278.2 2.8 4e-83 277.9 2.0 1.1 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF2456 PF10445.4 KFH48585.1 - 0.11 12.3 1.9 0.2 11.5 0.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2456) QueT PF06177.6 KFH48585.1 - 0.18 11.7 4.7 0.081 12.9 1.0 1.9 2 0 0 2 2 2 0 QueT transporter DUF1212 PF06738.7 KFH48586.1 - 6.8e-57 192.0 4.4 2.9e-53 180.2 0.2 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KFH48586.1 - 2.8e-21 75.8 30.9 6.9e-14 51.8 0.6 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3815) DUF3887 PF13026.1 KFH48586.1 - 0.023 14.9 0.2 29 5.0 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3887) CBM_19 PF03427.8 KFH48587.1 - 0.16 11.7 0.3 0.24 11.1 0.2 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) Sugar_tr PF00083.19 KFH48588.1 - 1.5e-130 435.8 22.2 1.7e-130 435.6 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH48588.1 - 9.5e-23 80.4 38.0 4.6e-22 78.1 25.1 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily HECT PF00632.20 KFH48589.1 - 8.3e-78 261.7 0.0 1.1e-77 261.3 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) 4HBT PF03061.17 KFH48590.1 - 2e-12 47.0 0.1 3.3e-12 46.3 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily MaoC_dehydratas PF01575.14 KFH48590.1 - 0.00095 18.5 0.0 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain DUF4442 PF14539.1 KFH48590.1 - 0.0027 17.6 0.1 0.0048 16.8 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4442) Acyl-ACP_TE PF01643.12 KFH48590.1 - 0.016 14.1 0.0 0.022 13.6 0.0 1.1 1 0 0 1 1 1 0 Acyl-ACP thioesterase 4HBT_2 PF13279.1 KFH48590.1 - 0.11 12.9 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily Glyco_hydro_15 PF00723.16 KFH48591.1 - 4.6e-93 312.2 0.0 6.9e-93 311.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 KFH48591.1 - 3.3e-31 106.7 0.3 7e-31 105.6 0.2 1.6 1 0 0 1 1 1 1 Starch binding domain adh_short_C2 PF13561.1 KFH48592.1 - 3.6e-32 112.0 0.1 4.2e-32 111.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFH48592.1 - 8.4e-32 110.3 1.1 1.3e-31 109.7 0.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH48592.1 - 1.9e-14 53.7 0.4 3.2e-14 53.0 0.3 1.3 1 0 0 1 1 1 1 KR domain P5CR_dimer PF14748.1 KFH48592.1 - 0.063 13.2 0.3 0.31 11.0 0.1 2.0 2 0 0 2 2 2 0 Pyrroline-5-carboxylate reductase dimerisation Ribosomal_L3 PF00297.17 KFH48593.1 - 9.6e-119 395.5 7.8 1.2e-118 395.3 5.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Sulfotransfer_3 PF13469.1 KFH48594.1 - 0.00095 20.1 4.8 0.0016 19.4 2.8 1.9 1 1 0 1 1 1 1 Sulfotransferase family COX6B PF02297.12 KFH48595.1 - 1.8e-18 66.3 3.7 2.1e-18 66.1 2.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 KFH48595.1 - 0.0034 16.7 0.4 0.0052 16.1 0.3 1.5 1 0 0 1 1 1 1 APOBEC-like C-terminal domain Methyltransf_23 PF13489.1 KFH48596.1 - 1e-10 41.5 0.0 1.7e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH48596.1 - 6.7e-09 36.1 0.0 1.7e-08 34.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH48596.1 - 1.1e-07 32.2 0.0 1.9e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH48596.1 - 0.00064 19.3 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFH48596.1 - 0.0079 16.5 0.0 0.016 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFH48596.1 - 0.02 14.0 0.0 0.22 10.6 0.0 2.0 1 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KFH48596.1 - 0.14 12.7 0.0 0.66 10.5 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain CAP_GLY PF01302.20 KFH48597.1 - 2.2e-23 81.7 1.5 3.4e-23 81.1 1.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 KFH48597.1 - 9.4e-21 73.8 0.0 1.9e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 KFH48597.1 - 7.5e-05 22.0 0.0 0.00015 21.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family tRNA-synt_2 PF00152.15 KFH48598.1 - 3.3e-88 295.6 0.1 4.5e-88 295.2 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KFH48598.1 - 6.5e-09 35.5 0.0 1.5e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KFH48598.1 - 1.3e-08 34.3 0.0 7.6e-05 22.0 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) GDC-P PF02347.11 KFH48599.1 - 5.2e-160 532.8 0.0 6.7e-147 489.6 0.0 3.7 3 1 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 KFH48599.1 - 2.9e-06 26.6 0.0 6.1e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 KFH48599.1 - 0.026 12.8 0.0 0.16 10.2 0.0 2.0 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme AP_endonuc_2 PF01261.19 KFH48600.1 - 1.7e-25 89.5 0.0 2.2e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel FAR1 PF03101.10 KFH48601.1 - 0.0053 17.2 0.3 0.0053 17.2 0.2 2.4 2 0 0 2 2 2 1 FAR1 DNA-binding domain PAT1 PF09770.4 KFH48601.1 - 0.052 11.7 40.2 0.059 11.6 27.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_U57 PF05582.7 KFH48601.1 - 0.26 10.1 4.6 0.4 9.6 3.2 1.2 1 0 0 1 1 1 0 YabG peptidase U57 DUF3043 PF11241.3 KFH48601.1 - 1.8 8.1 14.2 3.1 7.3 9.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Chorismate_bind PF00425.13 KFH48602.1 - 3.2e-88 295.3 0.0 7.3e-88 294.2 0.0 1.6 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 KFH48602.1 - 4.4e-28 98.0 0.2 2.3e-24 86.0 0.0 3.3 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region Pyr_redox_3 PF13738.1 KFH48603.1 - 1.1e-19 71.3 0.0 1.9e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFH48603.1 - 7.6e-06 24.4 0.0 1.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KFH48603.1 - 1.3e-05 25.1 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFH48603.1 - 4.3e-05 23.4 0.0 0.00027 20.9 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFH48603.1 - 0.039 12.8 0.1 2.7 6.8 0.0 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 KFH48603.1 - 0.19 10.7 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Thioredoxin_7 PF13899.1 KFH48604.1 - 8.6e-12 44.9 0.0 1.8e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.1 KFH48604.1 - 6.9e-11 41.5 0.0 1.4e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 KFH48604.1 - 7.4e-08 32.3 0.0 1.3e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 UBX domain RE_ApaLI PF09499.5 KFH48604.1 - 0.047 13.0 0.0 0.083 12.2 0.0 1.4 1 0 0 1 1 1 0 ApaLI-like restriction endonuclease Ribosomal_60s PF00428.14 KFH48604.1 - 3.6 8.0 9.6 4.3 7.8 0.9 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Peptidase_C48 PF02902.14 KFH48605.1 - 4.7e-21 75.4 0.0 8.7e-21 74.5 0.0 1.4 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain HPP PF04982.8 KFH48606.1 - 6.4e-38 129.2 5.9 6.4e-38 129.2 4.1 1.5 2 0 0 2 2 2 1 HPP family RskA PF10099.4 KFH48606.1 - 1.4 8.6 4.9 1.2 8.8 1.0 2.2 1 1 1 2 2 2 0 Anti-sigma-K factor rskA AMP-binding PF00501.23 KFH48607.1 - 5.8e-295 976.9 0.0 1.1e-101 340.3 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 KFH48607.1 - 3.3e-245 810.9 15.3 9.8e-87 290.5 1.9 4.7 5 0 0 5 5 5 4 Condensation domain Thioesterase PF00975.15 KFH48607.1 - 5.5e-45 154.3 0.0 1.4e-44 153.0 0.0 1.8 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 KFH48607.1 - 2.4e-42 143.0 0.2 2e-13 50.4 0.0 4.0 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KFH48607.1 - 1.2e-35 122.3 0.0 9.1e-12 45.7 0.0 4.9 5 0 0 5 5 5 3 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 KFH48607.1 - 2.5e-24 85.3 0.5 2.7e-17 62.8 0.4 4.0 3 0 0 3 3 3 2 HxxPF-repeated domain Abhydrolase_6 PF12697.2 KFH48607.1 - 3e-07 30.5 0.2 8e-06 25.8 0.0 3.3 4 0 0 4 4 4 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFH48607.1 - 0.0039 16.9 0.1 0.014 15.1 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family GH3 PF03321.8 KFH48607.1 - 0.096 11.1 0.1 20 3.5 0.0 3.5 4 0 0 4 4 4 0 GH3 auxin-responsive promoter Zn_clus PF00172.13 KFH48608.1 - 3.3e-08 33.2 9.0 5.7e-08 32.5 6.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFH48608.1 - 2.3e-07 29.7 1.2 4e-07 28.9 0.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF726 PF05277.7 KFH48609.1 - 1.1e-89 300.7 0.0 1.7e-89 300.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Cyclase PF04199.8 KFH48610.1 - 2.8e-15 56.4 0.0 4.2e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase NAD_binding_10 PF13460.1 KFH48611.1 - 1.7e-13 50.9 0.3 2.5e-13 50.4 0.2 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFH48611.1 - 0.00013 21.4 0.0 0.00024 20.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DHHA1 PF02272.14 KFH48611.1 - 0.0069 16.0 0.0 0.2 11.4 0.0 2.6 2 0 0 2 2 2 1 DHHA1 domain DUF1510 PF07423.6 KFH48612.1 - 0.31 10.3 12.8 0.02 14.3 4.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Fungal_trans PF04082.13 KFH48613.1 - 1.6e-22 79.6 0.1 3.7e-22 78.4 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH48613.1 - 1.2e-05 25.1 9.3 1.9e-05 24.4 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.17 KFH48614.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1343 PF07075.6 KFH48615.1 - 1.4e-114 382.7 0.0 1.6e-114 382.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1343) SinI PF08671.5 KFH48615.1 - 0.059 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Anti-repressor SinI S10_plectin PF03501.10 KFH48616.1 - 7.2e-42 141.1 0.1 8.6e-42 140.9 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain COG5 PF10392.4 KFH48617.1 - 0.0022 17.9 2.6 0.032 14.2 0.3 3.4 3 1 0 3 3 3 1 Golgi transport complex subunit 5 DUF4142 PF13628.1 KFH48617.1 - 0.0045 17.0 1.1 0.3 11.0 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4142) Baculo_PEP_C PF04513.7 KFH48617.1 - 0.11 12.3 2.9 0.3 10.9 1.4 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tmemb_cc2 PF10267.4 KFH48617.1 - 0.3 9.6 4.8 1.8 7.0 0.2 2.2 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein DUF445 PF04286.7 KFH48617.1 - 0.34 10.4 4.5 1.1 8.7 1.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF445) UVR PF02151.14 KFH48617.1 - 1.5 8.3 5.3 3 7.4 1.8 2.7 2 0 0 2 2 2 0 UvrB/uvrC motif Homeobox_KN PF05920.6 KFH48618.1 - 1.1e-13 50.5 1.3 3.3e-13 49.0 0.9 1.9 1 0 0 1 1 1 1 Homeobox KN domain HTH_Tnp_Tc5 PF03221.11 KFH48618.1 - 1.6e-13 50.2 5.4 7.8e-06 25.6 0.0 5.3 5 1 0 5 5 5 3 Tc5 transposase DNA-binding domain Homeobox PF00046.24 KFH48618.1 - 0.00014 21.4 0.2 0.00014 21.4 0.2 2.3 2 0 0 2 2 2 1 Homeobox domain zf-C2H2 PF00096.21 KFH48618.1 - 0.0012 19.0 13.9 0.034 14.4 2.6 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFH48618.1 - 0.015 15.6 4.2 0.015 15.6 2.9 5.2 6 0 0 6 6 6 0 C2H2-type zinc finger Zn_clus PF00172.13 KFH48618.1 - 0.78 9.7 3.3 4.2 7.3 2.3 2.2 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TF_Zn_Ribbon PF08271.7 KFH48618.1 - 3.4 7.0 5.9 5.3 6.4 0.1 3.1 3 0 0 3 3 3 0 TFIIB zinc-binding DUF974 PF06159.8 KFH48619.1 - 1.1e-79 267.3 0.0 1.5e-79 266.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) B12D PF06522.6 KFH48620.1 - 2.2e-06 27.2 0.0 3.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit ATP-grasp_2 PF08442.5 KFH48621.1 - 1.9e-06 27.4 0.0 3.1e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain SPRY PF00622.23 KFH48622.1 - 2.6e-08 33.9 0.0 2.5e-07 30.7 0.0 2.5 3 0 0 3 3 3 1 SPRY domain KH_1 PF00013.24 KFH48623.1 - 2.8e-11 42.8 0.1 1.3e-07 31.1 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 KFH48623.1 - 2e-06 27.2 4.8 3.2e-05 23.4 0.1 3.0 3 0 0 3 3 3 2 KH domain DUF4410 PF14366.1 KFH48623.1 - 0.1 12.3 0.1 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4410) Fungal_trans_2 PF11951.3 KFH48624.1 - 8.4e-06 24.6 2.1 1.9e-05 23.4 1.3 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KFH48625.1 - 3.7e-35 121.2 38.6 1.2e-20 73.4 2.8 3.0 3 0 0 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH48625.1 - 0.001 17.7 4.2 0.001 17.7 2.9 3.4 3 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 KFH48626.1 - 2e-69 234.3 23.4 2.6e-69 234.0 16.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KFH48626.1 - 1.1e-19 70.4 60.8 1.9e-18 66.3 39.8 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4066 PF13278.1 KFH48628.1 - 8.5e-22 77.1 0.2 6.7e-19 67.7 0.0 2.0 2 0 0 2 2 2 2 Putative amidotransferase DJ-1_PfpI PF01965.19 KFH48628.1 - 4.2e-06 26.2 0.0 8.1e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family SNO PF01174.14 KFH48628.1 - 0.0079 15.8 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 SNO glutamine amidotransferase family Sugar_tr PF00083.19 KFH48629.1 - 2.2e-92 310.0 16.4 2.6e-92 309.7 11.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH48629.1 - 3.8e-20 71.9 35.0 5.7e-14 51.6 4.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3425 PF11905.3 KFH48630.1 - 8e-23 80.8 0.2 1.8e-22 79.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) OTCace PF00185.19 KFH48631.1 - 2.9e-39 134.4 0.0 4.6e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 KFH48631.1 - 6.2e-39 132.8 0.0 8.9e-39 132.3 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Adeno_PVIII PF01310.13 KFH48631.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Adenovirus hexon associated protein, protein VIII RRM_1 PF00076.17 KFH48632.1 - 1.4e-47 159.1 0.0 1.5e-16 59.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH48632.1 - 5.1e-27 93.6 0.0 6e-10 38.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH48632.1 - 7.1e-21 73.8 0.1 1.3e-08 34.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFH48632.1 - 3e-06 26.8 0.1 0.0033 17.1 0.0 3.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KFH48632.1 - 6.8e-06 25.8 0.0 0.00015 21.6 0.0 2.5 3 0 0 3 3 3 1 RNA binding motif PHD PF00628.24 KFH48633.1 - 6.9e-10 38.4 8.2 1.1e-09 37.7 5.7 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 KFH48633.1 - 2.8e-06 27.5 0.6 2.2e-05 24.6 0.4 2.2 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding SOR_SNZ PF01680.12 KFH48634.1 - 1.2e-104 348.4 7.2 1.8e-104 347.8 5.0 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 KFH48634.1 - 9.2e-11 41.2 4.1 7.1e-07 28.5 0.1 2.5 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 KFH48634.1 - 3.2e-05 22.9 0.2 0.18 10.6 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) IGPS PF00218.16 KFH48634.1 - 0.00013 21.1 0.4 0.00053 19.1 0.0 2.1 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase His_biosynth PF00977.16 KFH48634.1 - 0.0015 17.8 0.3 0.037 13.3 0.0 2.8 3 0 0 3 3 3 1 Histidine biosynthesis protein MlrC_C PF07171.7 KFH48634.1 - 0.0059 16.1 0.6 0.013 15.0 0.4 1.6 1 0 0 1 1 1 1 MlrC C-terminus DUF4398 PF14346.1 KFH48634.1 - 0.0064 16.5 4.8 0.0078 16.2 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4398) NanE PF04131.9 KFH48634.1 - 0.0094 14.9 1.5 0.13 11.2 0.0 2.8 2 2 1 3 3 3 1 Putative N-acetylmannosamine-6-phosphate epimerase OMPdecase PF00215.19 KFH48634.1 - 0.02 14.3 0.3 0.028 13.8 0.2 1.4 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family NMO PF03060.10 KFH48634.1 - 5.1 6.1 13.5 0.73 8.9 2.8 2.8 2 2 0 2 2 2 0 Nitronate monooxygenase Hamartin PF04388.7 KFH48635.1 - 2.3e-39 135.6 16.0 4.4e-39 134.7 10.7 1.6 1 1 0 1 1 1 1 Hamartin protein V_ATPase_I PF01496.14 KFH48635.1 - 0.022 12.6 12.4 0.035 11.9 8.6 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.11 KFH48635.1 - 2.2 6.7 6.9 3.5 6.0 4.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein GATase PF00117.23 KFH48636.1 - 6.2e-46 156.2 0.0 8.7e-46 155.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 KFH48636.1 - 6.4e-46 155.1 0.0 1.1e-45 154.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.8 KFH48636.1 - 1.8e-06 27.5 0.1 0.00016 21.2 0.1 2.3 1 1 0 1 1 1 1 Peptidase C26 Glyco_transf_20 PF00982.16 KFH48637.1 - 3.3e-163 543.5 0.1 4.6e-163 543.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KFH48637.1 - 1.4e-45 155.0 0.0 2.2e-45 154.4 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase DUF718 PF05336.8 KFH48637.1 - 0.04 13.7 0.4 0.49 10.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF718) Glyco_transf_5 PF08323.6 KFH48637.1 - 0.079 12.4 0.3 0.15 11.5 0.2 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain DUF1681 PF07933.9 KFH48637.1 - 0.16 11.5 1.6 4.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1681) Choline_kinase PF01633.15 KFH48638.1 - 6.7e-61 205.5 0.0 1.3e-60 204.5 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 KFH48638.1 - 8.1e-19 66.8 0.0 1.5e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.18 KFH48638.1 - 2.5e-08 33.9 0.4 2.5e-08 33.9 0.3 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Reprolysin_5 PF13688.1 KFH48639.1 - 3.4e-58 196.8 1.5 1e-57 195.2 1.1 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KFH48639.1 - 7.4e-45 153.0 0.1 1.3e-44 152.1 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFH48639.1 - 5e-43 147.1 0.1 9.8e-43 146.1 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 KFH48639.1 - 1.9e-17 63.2 35.5 1.9e-17 63.2 24.6 4.8 3 1 2 5 5 5 1 Disintegrin Reprolysin_3 PF13582.1 KFH48639.1 - 3.8e-17 62.9 0.4 1.1e-16 61.5 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.14 KFH48639.1 - 1.7e-07 31.0 4.0 6.9e-06 25.7 2.8 3.1 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease RRM_1 PF00076.17 KFH48640.1 - 4.1e-20 71.1 0.0 5.8e-20 70.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH48640.1 - 5.4e-15 55.1 0.0 7.5e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH48640.1 - 4.6e-12 45.5 0.0 6.6e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFH48640.1 - 0.00015 21.4 0.0 0.00024 20.8 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 KFH48640.1 - 0.0017 18.0 0.0 0.0023 17.6 0.0 1.3 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF3237 PF11578.3 KFH48641.1 - 3.7e-12 45.7 0.0 5.2e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Mucin PF01456.12 KFH48641.1 - 2.6 7.8 18.9 5.3 6.8 13.1 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Pam17 PF08566.5 KFH48642.1 - 1.2e-60 204.2 0.0 1.5e-60 203.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 V_ATPase_I PF01496.14 KFH48643.1 - 3.8e-282 937.7 0.0 4.3e-282 937.5 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF4140 PF13600.1 KFH48643.1 - 0.016 15.6 2.6 0.37 11.2 0.3 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF3552 PF12072.3 KFH48643.1 - 0.13 11.4 3.8 5.9 6.0 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) PspB PF06667.7 KFH48643.1 - 0.16 11.8 1.9 1.5 8.7 0.1 3.0 3 0 0 3 3 3 0 Phage shock protein B Mod_r PF07200.8 KFH48643.1 - 0.27 11.1 2.4 16 5.3 0.1 2.3 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TBPIP PF07106.8 KFH48643.1 - 0.31 10.5 4.4 1.3 8.5 0.1 2.2 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Prefoldin_2 PF01920.15 KFH48643.1 - 0.44 10.3 2.6 7.9 6.2 0.1 2.4 2 0 0 2 2 2 0 Prefoldin subunit DUF1515 PF07439.6 KFH48643.1 - 0.69 9.7 0.0 0.69 9.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) HWE_HK PF07536.9 KFH48643.1 - 3.7 8.0 5.3 12 6.4 0.0 3.1 3 0 0 3 3 3 0 HWE histidine kinase DivIC PF04977.10 KFH48643.1 - 6.9 6.2 9.3 0.28 10.6 0.5 2.9 3 0 0 3 3 3 0 Septum formation initiator SCO1-SenC PF02630.9 KFH48644.1 - 5.2e-60 202.0 0.0 6.8e-60 201.6 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 KFH48644.1 - 0.00051 19.7 0.0 0.0013 18.4 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 KFH48644.1 - 0.002 18.2 0.0 0.0037 17.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like MFS_1 PF07690.11 KFH48645.1 - 1.5e-45 155.4 38.7 1.5e-45 155.4 26.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH48645.1 - 1.5e-07 30.3 31.1 1.8e-06 26.8 21.6 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 KFH48645.1 - 0.0025 15.9 13.7 0.0082 14.3 2.5 2.3 1 1 1 2 2 2 2 Transmembrane secretion effector OATP PF03137.15 KFH48645.1 - 0.48 8.4 7.7 0.064 11.3 0.2 2.6 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family PI-PLC-X PF00388.14 KFH48646.1 - 4.1e-43 146.2 0.0 6.9e-43 145.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KFH48646.1 - 1.3e-32 112.1 0.0 2e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 KFH48646.1 - 0.013 15.3 0.7 0.12 12.2 0.5 2.5 1 1 0 1 1 1 0 C2 domain Rep_fac_C PF08542.6 KFH48649.1 - 7.9e-23 80.2 0.0 2e-22 78.9 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KFH48649.1 - 3.7e-11 42.9 0.0 7.4e-11 41.9 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 KFH48649.1 - 3.4e-06 27.3 0.1 7.5e-06 26.1 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFH48649.1 - 5.6e-06 26.5 0.6 4.5e-05 23.5 0.2 2.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 KFH48649.1 - 0.00024 21.1 1.8 0.026 14.4 0.9 2.9 2 1 0 2 2 2 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 KFH48649.1 - 0.0017 18.3 0.2 0.074 13.1 0.2 2.5 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_33 PF13671.1 KFH48649.1 - 0.0033 17.3 0.1 0.0068 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KFH48649.1 - 0.018 15.2 0.0 0.053 13.8 0.0 1.8 1 1 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 KFH48649.1 - 0.035 13.7 0.0 0.069 12.8 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase DNA_pol3_delta PF06144.8 KFH48649.1 - 0.04 13.4 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit DUF2861 PF11060.3 KFH48649.1 - 0.047 13.0 0.0 0.11 11.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2861) T4SS-DNA_transf PF02534.9 KFH48649.1 - 0.065 11.7 0.1 0.14 10.6 0.0 1.5 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer SNF2_N PF00176.18 KFH48649.1 - 0.08 11.7 0.0 0.084 11.6 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_10 PF12846.2 KFH48649.1 - 0.12 11.7 0.2 2.1 7.6 0.0 2.3 1 1 0 2 2 2 0 AAA-like domain Mob1_phocein PF03637.12 KFH48650.1 - 3.4e-69 231.9 0.0 4.5e-69 231.6 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family Mito_fiss_reg PF05308.6 KFH48650.1 - 0.071 12.4 1.0 0.11 11.7 0.7 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Ank_2 PF12796.2 KFH48651.1 - 1.3e-63 211.2 3.1 8.2e-17 61.3 0.0 5.7 2 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KFH48651.1 - 3.7e-39 130.6 15.9 3.2e-07 29.8 0.0 11.4 11 0 0 11 11 11 8 Ankyrin repeat Ank_4 PF13637.1 KFH48651.1 - 1.2e-33 114.8 1.5 3e-07 30.7 0.1 8.0 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFH48651.1 - 9.8e-31 102.7 0.1 0.00018 21.4 0.0 10.5 12 0 0 12 12 12 6 Ankyrin repeat Ank_5 PF13857.1 KFH48651.1 - 1.3e-25 88.8 5.8 6.3e-07 29.4 0.0 8.0 5 2 4 9 9 9 6 Ankyrin repeats (many copies) Phage_T7_Capsid PF05396.6 KFH48651.1 - 0.022 14.8 0.0 8.8 6.4 0.0 3.9 3 1 1 4 4 4 0 Phage T7 capsid assembly protein Shigella_OspC PF06128.6 KFH48651.1 - 0.1 12.0 0.5 54 3.1 0.0 4.1 3 2 3 6 6 6 0 Shigella flexneri OspC protein DLH PF01738.13 KFH48653.1 - 1.6e-26 92.9 0.0 3.4e-26 91.8 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.6 KFH48653.1 - 0.018 14.7 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal OSCP PF00213.13 KFH48655.1 - 1.5e-43 148.6 0.8 1.8e-43 148.3 0.6 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit WD40 PF00400.27 KFH48656.1 - 6.5e-19 67.0 5.7 0.00018 21.2 0.0 6.6 6 1 1 7 7 7 5 WD domain, G-beta repeat SRA1 PF07304.6 KFH48656.1 - 1.6e-12 47.4 0.0 1.6e-12 47.4 0.0 2.2 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 KFH48656.1 - 4.6e-08 33.1 0.1 1.3e-07 31.6 0.0 1.6 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 SLX9 PF15341.1 KFH48657.1 - 1.9e-32 112.2 4.3 2.8e-32 111.7 3.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Peptidase_S28 PF05577.7 KFH48658.1 - 1.3e-52 178.8 0.0 7.7e-52 176.3 0.0 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase S28 p450 PF00067.17 KFH48659.1 - 2.1e-86 290.3 0.0 2.5e-86 290.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RRM_6 PF14259.1 KFH48660.1 - 7.4e-12 45.0 0.0 1.2e-09 38.0 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH48660.1 - 1.9e-11 43.6 0.0 8.1e-08 32.0 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFH48660.1 - 2.9e-09 36.4 0.1 4.1e-06 26.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFH48660.1 - 2.6e-06 27.0 0.0 0.007 16.1 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PWI PF01480.12 KFH48660.1 - 0.00077 19.5 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.19 KFH48660.1 - 0.0026 17.4 5.1 0.0053 16.4 3.5 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Transcrip_act PF04949.8 KFH48660.1 - 0.015 14.9 7.2 0.026 14.1 5.0 1.3 1 0 0 1 1 1 0 Transcriptional activator Exonuc_VII_L PF02601.10 KFH48660.1 - 0.018 14.2 0.2 0.023 13.8 0.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.4 KFH48660.1 - 0.58 9.0 9.5 0.84 8.5 6.6 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 OmpH PF03938.9 KFH48660.1 - 0.75 9.7 12.8 1.3 8.9 8.9 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Borrelia_P83 PF05262.6 KFH48660.1 - 2.9 6.0 10.8 4.2 5.5 7.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein VIT1 PF01988.14 KFH48660.1 - 3.1 7.2 5.6 5.5 6.4 3.9 1.4 1 0 0 1 1 1 0 VIT family V_ATPase_I PF01496.14 KFH48660.1 - 3.4 5.3 5.0 4.8 4.9 3.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RFC1 PF08519.7 KFH48661.1 - 6e-56 188.5 0.0 1.7e-55 187.0 0.0 1.8 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 KFH48661.1 - 4.4e-14 52.3 0.0 9.6e-14 51.2 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 KFH48661.1 - 7.3e-10 39.1 0.0 5.1e-09 36.4 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KFH48661.1 - 0.00018 21.1 0.1 0.00044 19.9 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 KFH48661.1 - 0.00031 21.5 0.0 0.00031 21.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain Rad17 PF03215.10 KFH48661.1 - 0.00032 19.5 0.0 0.00061 18.5 0.0 1.4 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KFH48661.1 - 0.00071 19.7 0.0 0.0045 17.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFH48661.1 - 0.0075 16.5 0.1 0.0075 16.5 0.1 2.5 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 KFH48661.1 - 0.011 15.7 0.7 0.072 13.0 0.1 2.6 2 1 1 3 3 3 0 AAA ATPase domain RuvB_N PF05496.7 KFH48661.1 - 0.034 13.1 0.0 0.064 12.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus PTCB-BRCT PF12738.2 KFH48661.1 - 0.038 13.8 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 twin BRCT domain NACHT PF05729.7 KFH48661.1 - 0.053 13.1 0.0 1.6 8.3 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.1 KFH48661.1 - 0.054 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFH48661.1 - 0.073 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KFH48661.1 - 0.098 12.3 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 KFH48661.1 - 0.1 12.3 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_28 PF13521.1 KFH48661.1 - 0.34 10.8 0.0 0.34 10.8 0.0 2.6 3 0 0 3 3 2 0 AAA domain Hydrolase_6 PF13344.1 KFH48662.1 - 3.9e-16 58.7 0.0 8.4e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFH48662.1 - 6.8e-13 48.1 0.0 1.9e-12 46.7 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KFH48662.1 - 0.033 14.6 0.0 0.47 10.8 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Glyco_trans_1_4 PF13692.1 KFH48663.1 - 1e-05 25.7 0.0 2.9e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF4319 PF14203.1 KFH48663.1 - 0.03 13.8 0.1 2.5 7.7 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4319) FYVE_2 PF02318.11 KFH48664.1 - 0.046 13.6 16.2 0.28 11.1 1.6 3.4 3 0 0 3 3 3 0 FYVE-type zinc finger Tnp_zf-ribbon_2 PF13842.1 KFH48664.1 - 0.5 10.8 0.1 0.5 10.8 0.1 5.1 4 2 0 4 4 4 0 DDE_Tnp_1-like zinc-ribbon Prenyltransf PF01255.14 KFH48665.1 - 4e-87 291.0 0.0 5.7e-87 290.5 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase C2 PF00168.25 KFH48666.1 - 4.5e-09 36.0 0.0 7.7e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain TRAPPC10 PF12584.3 KFH48667.1 - 1.3e-22 79.8 0.1 4.3e-22 78.2 0.0 1.9 2 0 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 MutS_V PF00488.16 KFH48668.1 - 1.4e-73 247.1 0.0 2.7e-73 246.2 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KFH48668.1 - 3.5e-36 124.9 1.7 1.4e-35 122.9 1.2 2.0 1 1 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 KFH48668.1 - 4.4e-09 36.4 0.1 1.2e-08 34.9 0.1 1.9 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 KFH48668.1 - 8.7e-08 32.3 0.0 4.1e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 MutS domain II Mak10 PF04112.8 KFH48669.1 - 1.5e-45 154.4 0.0 1.6e-24 86.0 0.0 2.6 1 1 0 2 2 2 2 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase CHCH PF06747.8 KFH48670.1 - 3.6e-07 29.9 15.8 7.2e-06 25.7 3.7 2.6 3 0 0 3 3 3 2 CHCH domain Cmc1 PF08583.5 KFH48670.1 - 0.26 11.0 11.0 0.13 12.0 0.5 2.5 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 KFH48670.1 - 1.8 8.6 8.7 4 7.5 4.2 2.4 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 UCR_hinge PF02320.11 KFH48670.1 - 4.1 7.4 7.0 2.4 8.1 3.0 2.1 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein COX6B PF02297.12 KFH48670.1 - 8.6 6.4 12.9 10 6.2 3.7 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb PCI PF01399.22 KFH48672.1 - 1.2e-20 73.7 0.1 4.7e-20 71.8 0.0 2.1 2 0 0 2 2 2 1 PCI domain TPR_8 PF13181.1 KFH48672.1 - 3.7e-05 23.1 1.4 8.4 6.4 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat DDRGK PF09756.4 KFH48672.1 - 0.00022 20.7 0.1 0.00022 20.7 0.1 2.0 2 0 0 2 2 2 1 DDRGK domain TPR_7 PF13176.1 KFH48672.1 - 0.0023 17.5 1.3 5.8 6.9 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat HTH_Crp_2 PF13545.1 KFH48672.1 - 0.037 13.8 0.6 0.18 11.6 0.1 2.4 2 1 0 2 2 2 0 Crp-like helix-turn-helix domain TPR_12 PF13424.1 KFH48672.1 - 0.17 11.8 10.2 0.3 11.0 0.1 4.4 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFH48672.1 - 0.2 12.3 13.1 5.3 7.8 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF87 PF01935.12 KFH48672.1 - 0.32 10.7 2.4 1.1 9.0 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function DUF87 DASH_Dad1 PF08649.5 KFH48673.1 - 9.6e-25 86.0 0.6 1.2e-24 85.8 0.4 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.5 KFH48673.1 - 0.079 12.8 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad4 WVELL PF14043.1 KFH48673.1 - 0.091 12.3 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 WVELL protein DUF605 PF04652.11 KFH48674.1 - 1.1 8.5 3.8 1.3 8.3 2.6 1.0 1 0 0 1 1 1 0 Vta1 like SART-1 PF03343.8 KFH48675.1 - 6.9e-160 533.3 53.7 7.9e-160 533.1 37.2 1.0 1 0 0 1 1 1 1 SART-1 family AHSA1 PF08327.6 KFH48676.1 - 0.039 14.0 0.0 0.074 13.1 0.0 1.4 1 0 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein Peptidase_M20 PF01546.23 KFH48678.1 - 6.9e-26 90.9 0.5 1e-25 90.3 0.4 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KFH48678.1 - 1.6e-19 69.7 0.0 2.9e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KFH48678.1 - 0.00021 21.1 0.0 0.00033 20.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.9 KFH48678.1 - 0.071 11.8 0.2 0.43 9.2 0.1 2.0 1 1 1 2 2 2 0 M42 glutamyl aminopeptidase MFS_1 PF07690.11 KFH48679.1 - 7.1e-50 169.6 40.7 3.5e-49 167.4 28.6 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH48679.1 - 1.5e-11 43.5 10.5 1.5e-11 43.5 7.3 3.4 2 2 2 4 4 4 1 Sugar (and other) transporter Mito_carr PF00153.22 KFH48680.1 - 5.6e-48 160.5 5.3 1.7e-16 59.6 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 KFH48680.1 - 0.00053 19.7 1.6 0.0017 18.1 0.7 2.2 2 1 0 2 2 2 1 UcrQ family DUF898 PF05987.8 KFH48680.1 - 0.077 11.8 3.2 0.21 10.4 0.2 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF898) Wzz PF02706.10 KFH48680.1 - 0.19 11.5 0.8 1.2 8.9 0.1 2.3 3 0 0 3 3 3 0 Chain length determinant protein Skp1_POZ PF03931.10 KFH48681.1 - 4.6e-11 42.6 0.0 6.5e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Mpv17_PMP22 PF04117.7 KFH48682.1 - 4.7e-12 45.3 6.6 1.5e-11 43.7 4.2 2.1 2 0 0 2 2 2 1 Mpv17 / PMP22 family DUF2456 PF10445.4 KFH48682.1 - 6.6 6.7 12.5 15 5.5 0.1 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2456) FMO-like PF00743.14 KFH48684.1 - 2.9e-16 58.7 0.0 7e-15 54.2 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KFH48684.1 - 6.2e-12 46.0 0.0 1.1e-11 45.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFH48684.1 - 1.6e-11 44.2 0.3 1.8e-10 40.7 0.0 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KFH48684.1 - 2.6e-09 36.9 0.1 2.1e-08 34.0 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFH48684.1 - 5e-07 29.7 0.0 9.5e-07 28.8 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFH48684.1 - 8.4e-07 28.2 0.0 2.3e-05 23.4 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 KFH48684.1 - 0.0036 16.4 0.0 0.0067 15.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 KFH48684.1 - 0.0045 15.9 0.0 0.02 13.7 0.0 2.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFH48684.1 - 0.014 15.7 0.5 5.3 7.5 0.2 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFH48684.1 - 0.021 13.8 0.1 0.04 12.9 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KFH48684.1 - 0.028 12.8 0.0 0.045 12.2 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein GET2 PF08690.5 KFH48685.1 - 9.9e-14 51.2 0.0 4.2e-12 45.9 0.0 2.0 2 0 0 2 2 2 2 GET complex subunit GET2 PEGSRP PF07623.6 KFH48686.1 - 0.86 8.9 3.5 1.2 8.5 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1584) Pkinase PF00069.20 KFH48687.1 - 8.9e-59 198.7 0.0 1.3e-58 198.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH48687.1 - 3.4e-37 127.9 0.0 9.1e-37 126.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH48687.1 - 3.6e-06 26.1 0.0 6.3e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFH48687.1 - 0.015 15.0 2.6 0.057 13.1 0.0 2.7 3 0 0 3 3 3 0 Phosphotransferase enzyme family AAA_13 PF13166.1 KFH48687.1 - 6.1 5.1 6.0 8.7 4.6 4.2 1.1 1 0 0 1 1 1 0 AAA domain Fungal_trans PF04082.13 KFH48688.1 - 4.9e-20 71.4 0.4 9.2e-20 70.5 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH48688.1 - 2.8e-07 30.3 13.4 5e-07 29.5 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RILP PF11461.3 KFH48688.1 - 0.0084 16.2 0.1 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 Rab interacting lysosomal protein Pox_A_type_inc PF04508.7 KFH48688.1 - 0.2 11.5 0.4 0.55 10.1 0.3 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Pex14_N PF04695.8 KFH48688.1 - 1 9.3 5.4 2 8.4 2.5 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Aldo_ket_red PF00248.16 KFH48689.1 - 1.8e-22 79.4 0.0 2.4e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 KFH48690.1 - 5e-39 133.9 33.8 7.9e-39 133.3 23.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFH48690.1 - 5.1e-19 68.1 22.7 7.3e-19 67.6 15.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KFH48690.1 - 3e-06 25.7 1.8 3e-06 25.7 1.2 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PAP2 PF01569.16 KFH48690.1 - 0.00017 21.2 0.6 0.00017 21.2 0.4 3.2 4 1 0 4 4 4 1 PAP2 superfamily DUF4112 PF13430.1 KFH48690.1 - 0.27 11.1 0.1 0.27 11.1 0.1 2.8 5 0 0 5 5 5 0 Domain of unknown function (DUF4112) PPI_Ypi1 PF07491.6 KFH48691.1 - 2.1e-24 84.8 0.1 6.3e-24 83.3 0.1 1.9 1 0 0 1 1 1 1 Protein phosphatase inhibitor SR-25 PF10500.4 KFH48691.1 - 0.076 12.4 18.0 0.12 11.8 12.5 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Syntaphilin PF15290.1 KFH48691.1 - 0.8 9.1 10.5 0.23 10.8 5.3 1.5 2 0 0 2 2 2 0 Golgi-localised syntaxin-1-binding clamp DUF1675 PF07897.6 KFH48691.1 - 5.7 6.7 12.3 6.7 6.4 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF3245 PF11595.3 KFH48691.1 - 6.1 7.1 11.7 0.24 11.6 3.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) SMC_Nse1 PF07574.8 KFH48692.1 - 4.5e-35 121.1 0.0 5.5e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 KFH48692.1 - 9.2e-11 41.5 5.4 1.4e-10 40.9 3.7 1.3 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.1 KFH48692.1 - 1.4 8.7 5.4 2.3 8.1 3.7 1.3 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.1 KFH48692.1 - 7.9 6.1 8.5 23 4.6 5.9 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain SNO PF01174.14 KFH48693.1 - 4.5e-57 192.7 0.0 1.2e-55 188.0 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 KFH48693.1 - 1.5e-09 37.6 0.0 9.4e-08 31.8 0.0 2.2 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 KFH48693.1 - 1.3e-05 24.7 0.0 0.0002 20.8 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.19 KFH48693.1 - 1.9e-05 24.1 0.0 2.4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 KFH48693.1 - 0.00058 19.1 0.1 0.00091 18.5 0.1 1.3 1 0 0 1 1 1 1 Putative amidotransferase Peptidase_S51 PF03575.12 KFH48693.1 - 0.062 13.0 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Peptidase family S51 TAF4 PF05236.9 KFH48694.1 - 8.8e-12 44.8 0.2 2.1e-10 40.3 0.2 2.8 2 1 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family WD40 PF00400.27 KFH48695.1 - 1.3e-07 31.2 14.0 0.00025 20.8 0.0 7.6 9 0 0 9 9 9 2 WD domain, G-beta repeat eIF2A PF08662.6 KFH48695.1 - 0.037 13.7 0.1 12 5.5 0.0 3.4 4 0 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 KFH48695.1 - 0.085 10.6 0.0 0.16 9.7 0.0 1.5 2 0 0 2 2 2 0 IKI3 family MMR_HSR1 PF01926.18 KFH48696.1 - 3.3e-06 27.0 0.0 1.4e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Oxidored_FMN PF00724.15 KFH48698.1 - 2.4e-63 214.1 0.0 3.2e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AIG2_2 PF13772.1 KFH48699.1 - 0.00014 21.8 0.0 0.025 14.7 0.0 2.3 2 0 0 2 2 2 2 AIG2-like family DS PF01916.12 KFH48700.1 - 6.8e-145 481.7 0.0 7.9e-145 481.5 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Pkinase PF00069.20 KFH48701.1 - 3.2e-70 236.2 0.0 4.4e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH48701.1 - 1.2e-50 172.0 0.0 2e-50 171.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH48701.1 - 0.0013 17.7 0.0 0.0038 16.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Aminotran_4 PF01063.14 KFH48702.1 - 2e-25 89.6 0.0 2.7e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Cas1_AcylT PF07779.7 KFH48703.1 - 5.3e-47 160.4 0.0 1.9e-24 86.0 0.0 2.1 2 0 0 2 2 2 2 10 TM Acyl Transferase domain found in Cas1p Acyl_transf_3 PF01757.17 KFH48703.1 - 0.035 12.9 9.8 0.63 8.8 0.3 2.2 2 0 0 2 2 2 0 Acyltransferase family WD40 PF00400.27 KFH48704.1 - 8.4e-28 95.2 5.4 1.3e-06 28.0 0.0 7.6 8 0 0 8 8 8 7 WD domain, G-beta repeat TPR_11 PF13414.1 KFH48705.1 - 3.4e-47 157.9 43.4 7.7e-14 51.0 1.2 6.4 2 2 5 8 8 8 8 TPR repeat TPR_1 PF00515.23 KFH48705.1 - 4.8e-47 155.7 34.0 4.1e-08 32.5 0.0 10.6 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 KFH48705.1 - 6.2e-42 138.1 23.8 1.5e-05 24.5 0.0 10.3 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_16 PF13432.1 KFH48705.1 - 9e-33 112.2 16.6 6.3e-08 33.0 0.1 6.8 4 1 1 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.1 KFH48705.1 - 1.8e-31 105.4 21.9 7.5e-06 25.3 0.6 10.2 8 1 2 10 10 10 7 Tetratricopeptide repeat TPR_17 PF13431.1 KFH48705.1 - 5.9e-27 91.5 23.6 0.0015 18.5 0.1 9.4 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.1 KFH48705.1 - 5e-24 84.0 26.0 2.2e-06 27.4 1.4 7.2 2 2 6 8 8 8 7 Tetratricopeptide repeat TPR_19 PF14559.1 KFH48705.1 - 1.5e-23 82.9 17.3 1e-06 28.9 0.1 6.7 5 2 1 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 KFH48705.1 - 1.3e-22 78.1 14.4 0.0065 17.0 0.1 9.4 3 2 6 9 9 9 7 Tetratricopeptide repeat TPR_7 PF13176.1 KFH48705.1 - 1.6e-19 68.0 12.0 0.0015 18.2 0.0 9.7 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_6 PF13174.1 KFH48705.1 - 2.3e-19 68.4 16.4 0.031 14.7 0.7 10.2 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.1 KFH48705.1 - 6.2e-12 45.1 10.7 0.00077 19.2 0.1 6.6 1 1 5 7 7 7 4 Tetratricopeptide repeat Apc3 PF12895.2 KFH48705.1 - 1.1e-11 44.7 11.4 5.1e-08 32.9 1.2 4.3 4 1 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 KFH48705.1 - 1.1e-08 34.4 9.0 0.06 12.3 0.4 5.1 1 1 4 5 5 5 4 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFH48705.1 - 8.4e-05 22.3 0.4 0.96 9.3 0.0 4.3 5 0 0 5 5 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.1 KFH48705.1 - 0.00011 22.2 0.3 0.67 10.1 0.0 4.0 2 1 1 3 3 3 1 Tetratricopeptide repeat DUF2225 PF09986.4 KFH48705.1 - 0.0036 16.7 4.3 0.09 12.2 0.1 2.8 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) ChAPs PF09295.5 KFH48705.1 - 0.064 12.0 0.1 9 4.9 0.0 2.4 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_21 PF09976.4 KFH48705.1 - 0.53 10.2 16.4 0.52 10.2 1.8 4.3 4 2 1 5 5 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 KFH48705.1 - 0.76 9.7 20.8 0.82 9.6 0.0 6.5 8 0 0 8 8 7 0 Tetratricopeptide repeat SNAP PF14938.1 KFH48705.1 - 1.2 8.2 16.5 8.9 5.3 3.1 4.3 1 1 1 3 3 3 0 Soluble NSF attachment protein, SNAP RPN7 PF10602.4 KFH48705.1 - 4.9 6.5 6.7 47 3.3 0.0 4.4 4 2 1 5 5 5 0 26S proteasome subunit RPN7 MFS_1 PF07690.11 KFH48706.1 - 6e-43 146.9 32.1 6e-43 146.9 22.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KFH48706.1 - 7.8e-10 37.5 1.9 1.1e-09 37.0 1.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KFH48706.1 - 1.8e-09 36.6 22.6 1.7e-08 33.4 16.1 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2178 PF09946.4 KFH48706.1 - 0.00022 20.9 0.9 0.00022 20.9 0.6 2.3 2 0 0 2 2 2 1 Predicted membrane protein (DUF2178) Methyltransf_11 PF08241.7 KFH48707.1 - 1e-10 41.9 0.0 1.8e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH48707.1 - 1.3e-07 31.3 0.0 1.9e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFH48707.1 - 4e-07 30.3 0.0 8e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH48707.1 - 4.2e-06 27.3 0.0 7.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFH48707.1 - 1.2e-05 25.3 0.9 2.7e-05 24.1 0.6 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH48707.1 - 1.4e-05 25.4 0.0 2.3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH48707.1 - 2.2e-05 24.2 0.0 3.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain K_oxygenase PF13434.1 KFH48709.1 - 5.2e-13 48.6 0.0 9.7e-08 31.2 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KFH48709.1 - 2.2e-09 37.6 0.0 0.00053 20.1 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFH48709.1 - 7.8e-05 21.8 0.1 0.0097 14.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 KFH48709.1 - 0.00019 21.4 0.0 0.012 15.4 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFH48709.1 - 0.00023 20.9 0.1 0.069 12.9 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KFH48709.1 - 0.0012 18.8 0.1 0.013 15.5 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KFH48709.1 - 0.0063 15.6 0.0 0.019 14.0 0.0 1.7 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 KFH48709.1 - 0.016 13.7 0.0 0.096 11.1 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.7 KFH48709.1 - 0.018 13.9 0.1 0.042 12.7 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.19 KFH48709.1 - 0.093 11.6 2.1 0.91 8.3 0.0 3.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFH48709.1 - 0.096 13.1 0.2 32 5.0 0.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase WD40 PF00400.27 KFH48711.1 - 1.7e-85 278.1 29.1 4.9e-16 57.9 0.4 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 KFH48711.1 - 9.2e-08 32.0 0.4 0.0012 18.6 0.0 3.9 2 2 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.4 KFH48711.1 - 4.5e-06 26.2 3.3 0.00017 21.0 0.0 3.1 2 1 1 3 3 3 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.3 KFH48711.1 - 6.5e-06 24.5 6.0 0.49 8.4 0.0 5.0 2 2 1 5 5 5 3 Nucleoporin Nup120/160 PD40 PF07676.7 KFH48711.1 - 3.9e-05 23.2 0.2 0.55 9.9 0.0 3.9 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat NLE PF08154.7 KFH48711.1 - 0.00022 21.1 0.0 0.00042 20.2 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Proteasome_A_N PF10584.4 KFH48711.1 - 0.034 13.4 0.0 11 5.4 0.0 3.7 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature AMP-binding PF00501.23 KFH48713.1 - 2.9e-66 223.5 0.0 3.8e-66 223.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFH48713.1 - 8.5e-10 39.4 0.0 1.9e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Telomere_Sde2 PF13019.1 KFH48714.1 - 3.9e-69 231.4 0.5 5.3e-69 231.0 0.3 1.2 1 0 0 1 1 1 1 Telomere stability and silencing DUF1675 PF07897.6 KFH48714.1 - 0.012 15.5 5.5 0.017 15.0 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) ubiquitin PF00240.18 KFH48714.1 - 0.026 13.9 0.0 0.056 12.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family DUF2407 PF10302.4 KFH48714.1 - 0.087 13.0 7.0 24 5.1 4.8 2.6 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain P16-Arc PF04699.9 KFH48717.1 - 4.3e-57 192.4 0.0 4.9e-57 192.2 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Fungal_trans PF04082.13 KFH48718.1 - 4.8e-15 55.1 0.0 9.2e-15 54.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH48718.1 - 1.2e-05 25.1 9.9 2.1e-05 24.3 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain L51_S25_CI-B8 PF05047.11 KFH48719.1 - 3.1e-18 65.2 0.2 5.4e-18 64.4 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF221 PF02714.10 KFH48720.1 - 3.3e-84 282.5 23.7 3.3e-84 282.5 16.4 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KFH48720.1 - 8.7e-42 142.3 1.0 8.7e-42 142.3 0.7 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KFH48720.1 - 7.5e-20 71.2 0.1 1.2e-19 70.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Glyco_hydro_cc PF11790.3 KFH48721.1 - 2.1e-57 194.2 1.5 2.6e-57 193.9 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Ala_racemase_N PF01168.15 KFH48723.1 - 2.4e-38 131.8 0.0 2.9e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain zf-RING_2 PF13639.1 KFH48724.1 - 9.6e-14 50.9 4.3 1.8e-13 50.0 3.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFH48724.1 - 3.7e-07 30.1 1.5 7.2e-07 29.2 1.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFH48724.1 - 6.2e-07 28.9 3.6 1e-06 28.2 2.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFH48724.1 - 4.4e-06 26.6 5.2 7.1e-06 25.9 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFH48724.1 - 1.3e-05 24.8 2.2 2.1e-05 24.1 1.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFH48724.1 - 4.2e-05 23.1 2.0 7.9e-05 22.2 1.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFH48724.1 - 0.017 14.9 0.8 0.036 13.9 0.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.1 KFH48724.1 - 0.031 14.0 2.9 0.31 10.8 1.3 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.1 KFH48724.1 - 0.14 11.7 2.9 0.28 10.7 2.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 KFH48724.1 - 0.48 10.1 2.7 1.1 9.0 1.9 1.7 1 0 0 1 1 1 0 PHD-finger WBS_methylT PF12589.3 KFH48725.1 - 5e-17 62.1 6.8 9.3e-17 61.2 4.7 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 KFH48725.1 - 2.1e-11 44.1 0.0 3.9e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH48725.1 - 8.2e-07 28.7 0.0 1.4e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFH48725.1 - 1.4e-06 28.5 0.0 3.2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH48725.1 - 1.8e-05 25.1 0.0 4.7e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH48725.1 - 3.1e-05 24.5 0.0 6e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFH48725.1 - 9.9e-05 22.3 0.0 0.0002 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH48725.1 - 0.00023 20.9 0.0 0.00033 20.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KFH48725.1 - 0.00052 19.5 0.0 0.001 18.6 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 KFH48725.1 - 0.034 13.2 0.0 1.2 8.1 0.0 2.1 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase HAUS5 PF14817.1 KFH48726.1 - 0.00047 18.8 1.1 0.00091 17.9 0.8 1.4 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 Shikimate_dh_N PF08501.6 KFH48727.1 - 3.4e-19 68.6 0.0 6e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 KFH48727.1 - 9e-12 45.2 0.0 1.3e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Ecm29 PF13001.2 KFH48728.1 - 3.7e-110 368.7 0.0 1.8e-109 366.5 0.0 2.0 2 0 0 2 2 2 1 Proteasome stabiliser HEAT_EZ PF13513.1 KFH48728.1 - 0.00088 19.6 12.7 1.1 9.8 0.1 7.2 7 0 0 7 7 7 2 HEAT-like repeat HEAT PF02985.17 KFH48728.1 - 0.00094 19.0 6.5 12 6.2 0.0 6.7 6 0 0 6 6 6 2 HEAT repeat Sec7_N PF12783.2 KFH48728.1 - 0.078 12.4 0.2 0.28 10.6 0.1 1.9 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Nup54 PF13874.1 KFH48729.1 - 4.9e-42 142.9 0.5 4.9e-42 142.9 0.3 2.2 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 KFH48729.1 - 6.9e-06 26.2 19.8 1.2e-05 25.4 13.7 1.4 1 0 0 1 1 1 1 Nucleoporin FG repeat region V-SNARE_C PF12352.3 KFH48729.1 - 0.0016 18.4 0.1 1.2 9.2 0.0 2.5 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus FUSC PF04632.7 KFH48729.1 - 0.015 13.7 7.8 0.025 13.0 5.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DivIVA PF05103.8 KFH48729.1 - 0.039 14.0 0.9 0.039 14.0 0.6 3.0 2 1 1 3 3 3 0 DivIVA protein Med13_N PF11597.3 KFH48729.1 - 0.28 9.8 7.3 0.41 9.2 5.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal Cep57_MT_bd PF06657.8 KFH48729.1 - 0.4 10.6 6.2 1.1 9.2 0.3 3.6 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 CCDC-167 PF15188.1 KFH48729.1 - 0.92 9.4 6.4 8.5 6.4 0.8 2.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF4208 PF13907.1 KFH48729.1 - 1.6 8.9 5.3 0.34 11.1 0.5 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4208) APG6 PF04111.7 KFH48729.1 - 2.7 6.9 6.7 4.1 6.3 3.8 1.9 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF4404 PF14357.1 KFH48729.1 - 4.5 7.7 9.7 6.2 7.3 0.3 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4404) bZIP_1 PF00170.16 KFH48729.1 - 4.6 7.2 7.5 28 4.7 0.9 3.4 2 1 2 4 4 4 0 bZIP transcription factor 2-Hacid_dh_C PF02826.14 KFH48730.1 - 2.4e-56 189.6 0.0 3.5e-56 189.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFH48730.1 - 3.5e-34 117.1 0.0 4.1e-34 116.9 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KFH48730.1 - 0.00018 21.3 0.0 0.00046 20.0 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 KFH48730.1 - 0.00028 20.7 0.1 0.00069 19.5 0.0 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 KFH48730.1 - 0.0064 15.8 0.0 0.13 11.5 0.0 2.2 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain Oxidored_nitro PF00148.14 KFH48730.1 - 0.016 13.8 0.0 0.017 13.7 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase CoA_binding_2 PF13380.1 KFH48730.1 - 0.076 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain ThiF PF00899.16 KFH48730.1 - 1.5 8.6 4.0 1e+02 2.6 1.6 3.6 4 0 0 4 4 4 0 ThiF family VSP PF03302.8 KFH48731.1 - 0.13 10.8 1.0 0.16 10.5 0.7 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Adaptin_N PF01602.15 KFH48732.1 - 6.6e-119 397.6 11.0 8e-119 397.3 7.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 KFH48732.1 - 5.3e-46 155.2 0.0 1.7e-45 153.6 0.0 1.9 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 KFH48732.1 - 3.6e-19 69.1 0.0 6.7e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain IMS PF00817.15 KFH48733.1 - 1e-36 125.9 0.0 2.1e-36 124.9 0.0 1.5 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 KFH48733.1 - 7.4e-10 38.8 0.0 1.4e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain Tom5 PF10642.4 KFH48734.1 - 2.8e-11 42.8 0.6 2.9e-11 42.8 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase DHquinase_II PF01220.14 KFH48735.1 - 2.4e-60 201.9 0.0 2.7e-60 201.7 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II MFS_1 PF07690.11 KFH48738.1 - 1.7e-32 112.5 38.5 5.9e-29 100.8 15.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily CENP-Q PF13094.1 KFH48739.1 - 3.8e-29 101.7 0.1 3.8e-29 101.7 0.1 3.1 3 1 0 4 4 4 1 CENP-Q, a CENPA-CAD centromere complex subunit MRG PF05712.8 KFH48740.1 - 2.4e-54 183.2 0.0 3.6e-54 182.6 0.0 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 KFH48740.1 - 7.8e-07 28.7 0.2 1.5e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DENN PF02141.16 KFH48741.1 - 1.1e-58 198.0 0.0 1.7e-58 197.4 0.0 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 KFH48741.1 - 4.9e-17 61.6 0.0 1.1e-16 60.5 0.0 1.7 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 KFH48741.1 - 5.6e-16 58.3 0.2 9.5e-16 57.6 0.1 1.4 1 0 0 1 1 1 1 dDENN domain C1_1 PF00130.17 KFH48741.1 - 0.0071 16.0 4.5 0.014 15.1 3.1 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 KFH48741.1 - 0.011 15.4 4.5 0.026 14.1 3.1 1.7 1 0 0 1 1 1 0 PHD-finger zf-PHD-like PF15446.1 KFH48741.1 - 0.099 11.9 1.6 0.19 10.9 1.1 1.4 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain C1_3 PF07649.7 KFH48741.1 - 0.25 11.4 3.5 0.5 10.4 2.4 1.5 1 0 0 1 1 1 0 C1-like domain Prok-RING_1 PF14446.1 KFH48741.1 - 0.47 10.2 4.3 0.92 9.2 3.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_2 PF03107.11 KFH48741.1 - 0.74 9.9 4.6 1.3 9.1 3.2 1.4 1 0 0 1 1 1 0 C1 domain Inositol_P PF00459.20 KFH48742.1 - 6e-78 261.8 0.0 7e-78 261.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Citrate_synt PF00285.16 KFH48744.1 - 2.7e-18 65.8 0.0 2.6e-15 56.0 0.0 3.1 1 1 1 2 2 2 2 Citrate synthase CoA_binding PF02629.14 KFH48744.1 - 3e-17 62.9 0.1 9.1e-17 61.3 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 KFH48744.1 - 1e-15 57.6 0.0 1.9e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 KFH48744.1 - 7.8e-06 25.5 0.0 0.00023 20.7 0.0 2.4 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Baculo_PEP_C PF04513.7 KFH48745.1 - 0.052 13.3 1.1 0.078 12.7 0.8 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FAD_binding_1 PF00667.15 KFH48747.1 - 3.6e-32 111.5 0.0 8.1e-32 110.4 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KFH48747.1 - 5.1e-29 101.1 0.0 7.7e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KFH48747.1 - 8.7e-18 64.8 0.0 1.8e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF2828 PF11443.3 KFH48748.1 - 6.7e-174 579.0 0.3 9.4e-174 578.5 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) ALS_ss_C PF10369.4 KFH48749.1 - 5.4e-19 67.7 0.0 8.6e-18 63.8 0.0 2.4 3 0 0 3 3 3 1 Small subunit of acetolactate synthase ACT PF01842.20 KFH48749.1 - 1.5e-11 43.5 0.1 2.7e-11 42.7 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 KFH48749.1 - 1.3e-09 37.6 0.0 2.5e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 KFH48749.1 - 0.044 13.5 0.0 4.6 7.0 0.0 2.7 2 1 0 2 2 2 0 ACT domain p450 PF00067.17 KFH48750.1 - 8.7e-57 192.6 0.0 1.8e-56 191.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 KFH48751.1 - 0.041 13.6 0.1 0.21 11.3 0.0 2.4 2 0 0 2 2 2 0 F-box-like LRR_8 PF13855.1 KFH48751.1 - 0.086 12.6 2.5 18 5.2 0.0 4.6 5 0 0 5 5 5 0 Leucine rich repeat Cnl2_NKP2 PF09447.5 KFH48752.1 - 1.8e-17 62.7 0.0 3.5e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 Cnl2/NKP2 family protein LXG PF04740.7 KFH48752.1 - 0.011 15.5 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 LXG domain of WXG superfamily Prefoldin_2 PF01920.15 KFH48752.1 - 0.029 14.1 0.1 0.074 12.8 0.0 1.7 1 0 0 1 1 1 0 Prefoldin subunit ATP-synt_B PF00430.13 KFH48752.1 - 0.14 11.9 2.3 2.8 7.7 0.0 2.2 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) KfrA_N PF11740.3 KFH48752.1 - 0.27 11.6 5.3 1.5 9.3 1.3 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Pex14_N PF04695.8 KFH48753.1 - 0.11 12.5 0.3 0.26 11.3 0.2 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region BAF1_ABF1 PF04684.8 KFH48753.1 - 1 8.1 17.4 1.5 7.5 12.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SAP PF02037.22 KFH48755.1 - 1.5e-11 43.4 0.3 2.3e-11 42.8 0.2 1.3 1 0 0 1 1 1 1 SAP domain CENP-R PF06729.7 KFH48755.1 - 0.3 10.7 3.1 0.66 9.6 2.2 1.5 1 0 0 1 1 1 0 Kinetochore component, CENP-R MS_channel PF00924.13 KFH48756.1 - 2.6e-18 66.1 2.0 4.4e-18 65.3 1.4 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 KFH48756.1 - 0.0058 15.8 0.1 0.013 14.7 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KFH48756.1 - 0.012 15.4 0.0 0.033 14.0 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.1 KFH48756.1 - 0.032 13.5 0.0 0.066 12.5 0.0 1.5 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.1 KFH48756.1 - 0.044 13.9 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair AMP-binding PF00501.23 KFH48757.1 - 2.3e-88 296.3 0.2 2.9e-88 296.0 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFH48757.1 - 1.8e-22 80.0 0.8 1.1e-19 71.1 0.8 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain DUF3712 PF12505.3 KFH48758.1 - 7.3e-09 35.7 0.2 5.4e-08 32.8 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) LEA_2 PF03168.8 KFH48758.1 - 1.1e-06 28.9 0.0 1.4 9.3 0.0 5.1 5 1 1 6 6 6 2 Late embryogenesis abundant protein Neurensin PF14927.1 KFH48758.1 - 0.039 13.3 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 Neurensin Fructosamin_kin PF03881.9 KFH48759.1 - 5.9e-34 117.3 0.0 9.9e-34 116.6 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase AAA_16 PF13191.1 KFH48759.1 - 3e-06 27.3 0.0 8.5e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 KFH48759.1 - 4.1e-05 23.3 0.0 8.8e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PGAP1 PF07819.8 KFH48759.1 - 0.00016 21.3 0.0 0.00031 20.4 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein APH PF01636.18 KFH48759.1 - 0.0033 17.1 1.0 0.0064 16.2 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family 6PF2K PF01591.13 KFH48759.1 - 0.014 14.5 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DUF829 PF05705.9 KFH48759.1 - 0.035 13.8 0.0 0.1 12.3 0.0 1.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF829) NB-ARC PF00931.17 KFH48759.1 - 0.092 11.5 0.0 0.25 10.1 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain SGL PF08450.7 KFH48759.1 - 0.11 11.8 0.1 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region Torsin PF06309.6 KFH48759.1 - 0.17 11.7 0.0 0.78 9.6 0.0 2.1 2 0 0 2 2 2 0 Torsin DUF676 PF05057.9 KFH48759.1 - 0.48 9.6 0.0 1.1 8.4 0.0 1.6 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF2075 PF09848.4 KFH48759.1 - 0.68 8.8 0.0 1.3 7.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) WD40 PF00400.27 KFH48759.1 - 9.4 6.2 12.3 15 5.6 0.1 4.9 6 0 0 6 6 5 0 WD domain, G-beta repeat CPSF73-100_C PF11718.3 KFH48761.1 - 2e-73 246.3 0.0 1.1e-69 234.1 0.0 2.2 2 0 0 2 2 2 2 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 KFH48761.1 - 2.8e-32 111.2 0.0 6.8e-32 110.0 0.0 1.7 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 KFH48761.1 - 1e-14 54.6 0.8 1.9e-14 53.7 0.6 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KFH48761.1 - 1.8e-12 47.1 0.5 3.5e-12 46.2 0.4 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 KFH48761.1 - 1.1e-06 28.3 0.3 2.2e-06 27.3 0.2 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 KFH48761.1 - 7.6e-06 25.7 0.2 1.9e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PBP PF01161.15 KFH48762.1 - 2.3e-19 69.6 0.0 2.7e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Peptidase_M20 PF01546.23 KFH48763.1 - 8.5e-26 90.6 0.0 1.5e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KFH48763.1 - 6.4e-11 41.9 0.0 1.2e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KFH48763.1 - 0.033 13.9 0.0 0.065 12.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 BTB PF00651.26 KFH48764.1 - 1.4e-25 89.4 0.0 1.1e-11 44.6 0.0 2.9 3 0 0 3 3 3 2 BTB/POZ domain Ank_2 PF12796.2 KFH48764.1 - 2.2e-09 37.5 0.0 6.3e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFH48764.1 - 2.9e-09 36.8 0.1 9.6e-06 25.6 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFH48764.1 - 7.5e-09 35.8 0.7 3.8e-08 33.6 0.1 2.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 KFH48764.1 - 1.6e-08 33.9 0.8 2.9e-05 23.6 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 KFH48764.1 - 3.5e-07 29.8 0.9 0.0074 16.4 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Imm41 PF15583.1 KFH48764.1 - 0.15 11.8 1.9 0.58 9.9 0.0 2.8 4 0 0 4 4 4 0 Immunity protein 41 Ribosomal_L16 PF00252.13 KFH48765.1 - 2.2e-27 95.3 0.6 3.1e-27 94.9 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DBR1 PF05011.8 KFH48766.1 - 3.6e-48 163.1 0.0 5.8e-48 162.4 0.0 1.3 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 KFH48766.1 - 1.9e-08 33.9 0.0 4e-08 32.8 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase ThiF PF00899.16 KFH48767.1 - 2.4e-41 140.7 0.0 4.5e-41 139.8 0.0 1.5 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 KFH48767.1 - 4.7e-23 80.5 0.0 8e-23 79.8 0.0 1.4 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 KFH48767.1 - 1.4e-11 44.7 0.0 3.9e-11 43.2 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.15 KFH48767.1 - 0.014 15.4 0.1 0.088 12.9 0.0 2.2 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Rpp20 PF12328.3 KFH48768.1 - 2.2e-29 101.9 2.3 3.3e-29 101.3 1.6 1.2 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 KFH48768.1 - 2.4e-18 65.4 0.1 3.6e-18 64.9 0.1 1.3 1 0 0 1 1 1 1 Alba TRSP PF12500.3 KFH48768.1 - 0.015 14.7 0.1 0.018 14.5 0.1 1.1 1 0 0 1 1 1 0 TRSP domain C terminus to PRTase_2 RRM_1 PF00076.17 KFH48769.1 - 5.3e-31 106.0 0.3 5.7e-15 54.7 0.0 3.4 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH48769.1 - 1.2e-24 86.0 0.0 2.2e-12 46.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH48769.1 - 2.2e-08 33.8 0.0 0.0035 17.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 KFH48769.1 - 0.004 16.7 0.4 5.4 6.7 0.0 3.1 3 0 0 3 3 3 2 DbpA RNA binding domain Limkain-b1 PF11608.3 KFH48769.1 - 0.076 12.7 0.3 18 5.1 0.0 2.8 3 0 0 3 3 3 0 Limkain b1 Glyco_hydro_63 PF03200.11 KFH48770.1 - 1.1e-07 30.2 1.6 2e-05 22.6 0.1 3.3 2 1 0 2 2 2 2 Mannosyl oligosaccharide glucosidase DUF2205 PF10224.4 KFH48771.1 - 3e-31 106.8 0.4 3.9e-31 106.4 0.2 1.2 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) YtxH PF12732.2 KFH48771.1 - 0.059 13.7 0.3 0.091 13.1 0.2 1.3 1 0 0 1 1 1 0 YtxH-like protein AAA_32 PF13654.1 KFH48771.1 - 0.074 11.6 0.3 0.093 11.3 0.2 1.0 1 0 0 1 1 1 0 AAA domain Spectrin PF00435.16 KFH48771.1 - 0.083 13.1 0.2 0.12 12.7 0.1 1.1 1 0 0 1 1 1 0 Spectrin repeat MTHFR PF02219.12 KFH48773.1 - 2.8e-114 381.0 0.0 4e-114 380.5 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase GrpE PF01025.14 KFH48774.1 - 8.6e-53 178.2 5.3 1.2e-52 177.8 3.7 1.2 1 0 0 1 1 1 1 GrpE TACC PF05010.9 KFH48774.1 - 0.012 15.3 2.5 0.014 15.1 1.7 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) DUF334 PF03904.8 KFH48774.1 - 0.017 14.4 0.4 0.024 13.9 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Bap31 PF05529.7 KFH48774.1 - 0.14 11.6 3.1 0.21 11.0 2.2 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like IncA PF04156.9 KFH48774.1 - 0.22 11.1 3.1 0.3 10.6 2.2 1.2 1 0 0 1 1 1 0 IncA protein UAA PF08449.6 KFH48775.1 - 1.9e-15 56.5 19.1 2.4e-15 56.2 13.2 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 KFH48775.1 - 3.3e-10 39.8 6.2 3.3e-10 39.8 4.3 2.4 1 1 1 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KFH48775.1 - 0.00091 19.2 6.6 0.00091 19.2 4.6 2.3 2 0 0 2 2 2 1 EamA-like transporter family PHO4 PF01384.15 KFH48775.1 - 0.0022 16.7 5.3 0.0022 16.7 3.7 2.3 1 1 1 2 2 2 1 Phosphate transporter family ETF PF01012.16 KFH48776.1 - 2e-37 128.4 0.6 2.6e-37 128.0 0.4 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain CN_hydrolase PF00795.17 KFH48777.1 - 2.5e-22 79.1 0.0 5.5e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 KFH48777.1 - 3.9e-19 68.5 0.0 2.8e-18 65.7 0.0 2.1 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 KFH48777.1 - 0.0045 16.5 0.0 0.0076 15.7 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase Dynamin_N PF00350.18 KFH48778.1 - 5.4e-29 101.1 0.0 1.3e-28 99.8 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KFH48778.1 - 1.2e-08 34.1 0.0 2.5e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 KFH48778.1 - 1.4e-05 24.9 0.0 3.1e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFH48778.1 - 0.012 16.1 0.0 0.026 15.0 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein DUF2077 PF09850.4 KFH48778.1 - 0.1 12.0 2.4 0.95 8.8 0.1 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2077) AAA_21 PF13304.1 KFH48778.1 - 0.28 11.1 0.0 0.46 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Chromo PF00385.19 KFH48779.1 - 1.4e-07 31.0 0.4 1.1e-06 28.2 0.4 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Ferritin_2 PF13668.1 KFH48780.1 - 0.014 15.3 0.4 0.021 14.7 0.2 1.2 1 0 0 1 1 1 0 Ferritin-like domain Laminin_G_3 PF13385.1 KFH48780.1 - 0.099 12.8 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily IF-2B PF01008.12 KFH48781.1 - 1.8e-75 253.5 0.9 2.1e-75 253.3 0.6 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family CAP PF00188.21 KFH48782.1 - 3.5e-21 75.9 2.7 4.7e-21 75.5 1.9 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Trypan_PARP PF05887.6 KFH48782.1 - 0.0099 15.7 37.4 0.0099 15.7 26.0 2.3 1 1 1 2 2 2 1 Procyclic acidic repetitive protein (PARP) DUF2413 PF10310.4 KFH48782.1 - 2.4 6.8 6.1 4.1 6.1 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Fungal_trans PF04082.13 KFH48783.1 - 2.6e-09 36.3 0.0 3.9e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH48783.1 - 3.3e-06 26.8 8.5 5.5e-06 26.1 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.14 KFH48784.1 - 4.2 7.3 60.5 0.5 10.2 2.4 6.6 6 0 0 6 6 6 0 AT hook motif Myb_DNA-binding PF00249.26 KFH48785.1 - 2.1e-07 30.8 0.0 2.1e-05 24.5 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain CUB_2 PF02408.15 KFH48786.1 - 0.11 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 CUB-like domain F-box-like PF12937.2 KFH48787.1 - 3.7e-08 32.9 0.1 7e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFH48787.1 - 8.7e-06 25.2 0.0 1.7e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 F-box domain UIM PF02809.15 KFH48787.1 - 8.8e-05 21.7 3.4 8.8e-05 21.7 2.3 3.4 4 0 0 4 4 4 2 Ubiquitin interaction motif Abp2 PF09441.5 KFH48788.1 - 3.8e-70 235.3 0.0 7.4e-70 234.4 0.0 1.3 1 0 0 1 1 1 1 ARS binding protein 2 DUF2435 PF10363.4 KFH48790.1 - 9.2e-12 44.7 1.5 6.4e-11 42.0 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 KFH48790.1 - 2.1e-11 43.0 0.0 7.3e-11 41.2 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) PBP1_TM PF14812.1 KFH48790.1 - 0.0075 16.5 5.5 0.021 15.1 3.8 1.7 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal AATF-Che1 PF13339.1 KFH48790.1 - 0.55 10.3 5.5 0.19 11.8 1.1 2.3 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor hDGE_amylase PF14701.1 KFH48791.1 - 1.4e-175 584.2 0.0 1.8e-175 583.8 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 KFH48791.1 - 2.2e-114 382.0 0.1 5.1e-114 380.8 0.0 1.6 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 KFH48791.1 - 4.2e-88 294.8 0.0 9e-88 293.8 0.0 1.6 2 0 0 2 2 2 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 KFH48791.1 - 3.2e-26 90.9 0.0 7.7e-26 89.7 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 KFH48791.1 - 8.9e-05 22.0 0.0 0.21 10.9 0.0 2.3 2 0 0 2 2 2 2 Alpha amylase, catalytic domain GATA PF00320.22 KFH48792.1 - 1.3e-32 110.8 16.9 3e-17 61.6 2.4 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 KFH48792.1 - 1.1e-05 24.6 4.1 0.028 13.7 0.1 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding ArfGap PF01412.13 KFH48792.1 - 0.0005 19.8 1.2 0.22 11.3 0.1 2.4 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf zf-ribbon_3 PF13248.1 KFH48792.1 - 0.0019 17.3 7.8 0.25 10.6 0.2 2.9 2 1 1 3 3 3 3 zinc-ribbon domain Zn-ribbon_8 PF09723.5 KFH48792.1 - 0.0043 16.9 2.4 1.1 9.2 0.1 2.9 2 0 0 2 2 2 1 Zinc ribbon domain RRN7 PF11781.3 KFH48792.1 - 0.0045 16.4 7.0 0.17 11.3 0.4 2.4 2 0 0 2 2 2 2 RNA polymerase I-specific transcription initiation factor Rrn7 NMD3 PF04981.8 KFH48792.1 - 0.051 12.6 0.2 2.9 6.9 0.0 2.3 2 0 0 2 2 2 0 NMD3 family HypA PF01155.14 KFH48792.1 - 0.097 12.3 1.6 1.8 8.3 0.1 2.5 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family COX5B PF01215.14 KFH48792.1 - 0.17 11.5 0.7 3.7 7.2 0.1 2.6 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Vb OrfB_Zn_ribbon PF07282.6 KFH48792.1 - 0.19 11.4 11.1 0.34 10.6 0.3 3.0 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.2 KFH48792.1 - 0.19 11.5 5.7 0.59 9.9 0.5 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Auto_anti-p27 PF06677.7 KFH48792.1 - 0.23 11.2 4.0 7.3 6.4 0.2 2.6 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-C2H2_3 PF13878.1 KFH48792.1 - 0.3 10.6 9.2 5.2 6.7 0.3 4.2 3 1 1 4 4 4 0 zinc-finger of acetyl-transferase ESCO Ribosomal_L32p PF01783.18 KFH48792.1 - 0.34 11.1 8.5 5 7.3 1.4 3.9 2 2 0 2 2 2 0 Ribosomal L32p protein family DZR PF12773.2 KFH48792.1 - 0.35 10.7 16.8 0.9 9.4 0.6 3.5 1 1 1 2 2 2 0 Double zinc ribbon zf-Sec23_Sec24 PF04810.10 KFH48792.1 - 0.37 10.4 8.6 0.12 11.9 0.3 2.9 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger zinc_ribbon_2 PF13240.1 KFH48792.1 - 4.7 6.8 12.1 0.54 9.8 0.2 3.5 4 0 0 4 4 4 0 zinc-ribbon domain Ras PF00071.17 KFH48793.1 - 8.7e-47 158.5 0.0 1.2e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFH48793.1 - 5.6e-11 42.9 0.0 9.1e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFH48793.1 - 9.8e-06 24.9 0.0 3.2e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family CobT PF06213.7 KFH48794.1 - 0.023 13.8 17.0 0.033 13.3 11.8 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BAF1_ABF1 PF04684.8 KFH48794.1 - 0.034 12.9 8.8 0.053 12.3 6.1 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Pox_Ag35 PF03286.9 KFH48794.1 - 0.36 10.3 6.6 0.43 10.0 4.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.7 KFH48794.1 - 0.88 7.4 19.5 1 7.2 13.5 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KFH48794.1 - 2.2 6.2 14.9 2.7 5.9 10.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop25 PF09805.4 KFH48794.1 - 8.6 6.4 8.8 13 5.8 6.1 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Asp PF00026.18 KFH48796.1 - 7.5e-09 35.2 0.3 1.1e-08 34.7 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease VSP PF03302.8 KFH48796.1 - 0.027 13.1 0.0 0.04 12.5 0.0 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Adeno_E3_CR2 PF02439.10 KFH48796.1 - 0.031 13.8 1.7 0.054 13.0 1.2 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 MLANA PF14991.1 KFH48796.1 - 0.046 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A Herpes_gE PF02480.11 KFH48796.1 - 0.08 11.1 0.0 0.14 10.4 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E ArfGap PF01412.13 KFH48797.1 - 1.8e-31 108.3 0.0 3.3e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-UBR PF02207.15 KFH48797.1 - 0.92 9.2 4.0 1.4 8.6 0.4 2.2 1 1 1 2 2 2 0 Putative zinc finger in N-recognin (UBR box) GTP_EFTU PF00009.22 KFH48798.1 - 1e-61 207.6 0.4 1.5e-61 207.1 0.3 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KFH48798.1 - 1.3e-37 127.9 0.0 3.8e-37 126.4 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 KFH48798.1 - 1.4e-21 76.1 0.0 4.2e-21 74.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 KFH48798.1 - 7.1e-12 45.0 0.0 2.1e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KFH48798.1 - 3e-11 43.2 1.2 8.4e-11 41.8 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KFH48798.1 - 1.8e-05 24.6 0.2 4.3e-05 23.4 0.2 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PAD_M PF08527.5 KFH48798.1 - 0.038 13.4 0.0 0.1 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) middle domain p450 PF00067.17 KFH48799.1 - 2.1e-46 158.3 0.0 2.5e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Aida_N PF08910.5 KFH48799.1 - 0.096 12.9 0.1 3.8 7.7 0.0 2.4 1 1 1 2 2 2 0 Aida N-terminus GFO_IDH_MocA PF01408.17 KFH48800.1 - 1.6e-17 64.1 0.2 2.6e-17 63.4 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold OpuAC PF04069.7 KFH48800.1 - 0.00099 18.5 0.2 2.1 7.6 0.0 3.3 3 0 0 3 3 3 3 Substrate binding domain of ABC-type glycine betaine transport system NAD_binding_3 PF03447.11 KFH48800.1 - 0.021 15.1 0.2 0.04 14.3 0.1 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Sugar_tr PF00083.19 KFH48801.1 - 1.6e-123 412.6 18.2 1.9e-123 412.4 12.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFH48801.1 - 1.2e-22 80.0 37.2 1.3e-15 57.0 9.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily YtpI PF14007.1 KFH48801.1 - 0.0038 17.1 1.7 0.0038 17.1 1.2 2.9 3 0 0 3 3 3 1 YtpI-like protein DUF2530 PF10745.4 KFH48801.1 - 0.11 12.5 2.2 0.19 11.7 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Zip PF02535.17 KFH48802.1 - 1.8e-45 155.3 4.4 5.3e-45 153.7 3.1 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter Sds3 PF08598.6 KFH48803.1 - 6.1e-48 163.0 0.9 3.3e-47 160.6 0.6 2.0 1 1 0 1 1 1 1 Sds3-like Acetyltransf_1 PF00583.19 KFH48804.1 - 1.4e-07 31.4 0.0 1.9e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFH48804.1 - 9.2e-07 28.9 0.0 1.5e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFH48804.1 - 0.0021 17.9 0.0 0.076 12.8 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFH48804.1 - 0.036 14.1 0.0 0.053 13.6 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFH48804.1 - 0.14 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Ribosomal_L30 PF00327.15 KFH48806.1 - 7.7e-17 60.6 0.1 9.5e-17 60.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e SNAP PF14938.1 KFH48807.1 - 3.6e-115 383.9 15.4 4.1e-115 383.7 10.7 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 KFH48807.1 - 8e-05 22.5 9.6 0.037 13.9 2.1 3.4 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFH48807.1 - 0.00093 18.8 6.6 0.54 10.1 0.7 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFH48807.1 - 0.0012 18.4 15.4 0.0044 16.6 0.5 3.8 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 KFH48807.1 - 0.0012 18.6 15.1 0.059 13.3 0.3 6.4 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFH48807.1 - 0.046 13.5 11.2 2.2 8.2 0.1 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Foie-gras_1 PF11817.3 KFH48807.1 - 0.066 12.6 1.3 0.14 11.6 0.9 1.6 1 0 0 1 1 1 0 Foie gras liver health family 1 DUF4170 PF13773.1 KFH48807.1 - 0.073 12.9 0.2 0.28 11.1 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4170) TPR_1 PF00515.23 KFH48807.1 - 0.32 10.6 15.7 0.2 11.3 0.3 5.2 6 1 1 7 7 7 0 Tetratricopeptide repeat Apc3 PF12895.2 KFH48807.1 - 1.8 8.7 8.0 0.34 11.0 1.2 2.9 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KFH48807.1 - 2.8 8.5 14.8 11 6.7 0.1 5.4 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFH48807.1 - 5.8 7.8 13.9 31 5.5 0.0 5.3 3 1 2 6 6 5 0 Tetratricopeptide repeat UreE_C PF05194.7 KFH48809.1 - 0.0075 16.3 3.8 0.011 15.8 2.0 1.7 2 0 0 2 2 2 1 UreE urease accessory protein, C-terminal domain DUF1319 PF07028.6 KFH48809.1 - 0.021 15.0 0.1 0.03 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) NUP PF06516.6 KFH48809.1 - 0.022 13.6 0.1 0.027 13.2 0.0 1.1 1 0 0 1 1 1 0 Purine nucleoside permease (NUP) Ead_Ea22 PF13935.1 KFH48809.1 - 0.024 14.9 0.2 0.034 14.4 0.1 1.3 1 0 0 1 1 1 0 Ead/Ea22-like protein Pox_A_type_inc PF04508.7 KFH48809.1 - 0.034 13.9 1.0 0.05 13.3 0.0 1.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF2365 PF10157.4 KFH48809.1 - 0.043 13.6 0.2 0.058 13.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) PFL PF02901.10 KFH48809.1 - 0.084 11.2 0.2 0.099 11.0 0.1 1.0 1 0 0 1 1 1 0 Pyruvate formate lyase PSK_trans_fac PF07704.6 KFH48810.1 - 1.9 9.2 5.1 1.3 9.7 0.4 2.5 2 1 0 2 2 2 0 Rv0623-like transcription factor NAD_Gly3P_dh_N PF01210.18 KFH48811.1 - 4.7e-46 156.3 0.0 8.3e-46 155.5 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 KFH48811.1 - 3.6e-42 143.5 0.3 5.9e-42 142.8 0.2 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 KFH48811.1 - 0.023 15.1 0.0 9.2 6.7 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Malic_M PF03949.10 KFH48811.1 - 0.071 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Iso_dh PF00180.15 KFH48813.1 - 1.3e-77 261.1 0.0 1.5e-77 260.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Glu-tRNAGln PF02686.10 KFH48814.1 - 1e-06 28.3 0.1 2.6e-05 23.9 0.0 2.2 2 0 0 2 2 2 2 Glu-tRNAGln amidotransferase C subunit Clr2 PF10383.4 KFH48816.1 - 5.8e-07 29.5 0.0 1.9e-06 27.9 0.0 1.9 1 1 0 1 1 1 1 Transcription-silencing protein Clr2 PAT1 PF09770.4 KFH48816.1 - 3.8 5.6 15.4 5.4 5.1 10.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 2OG-FeII_Oxy PF03171.15 KFH48817.1 - 5e-20 71.6 0.0 1.3e-19 70.2 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KFH48817.1 - 4.6e-13 49.7 0.0 7.7e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Glyco_hydro_20 PF00728.17 KFH48817.1 - 0.0049 16.0 0.6 0.018 14.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, catalytic domain ATP-synt_Eps PF04627.8 KFH48819.1 - 2.3e-23 81.4 2.9 3.6e-23 80.8 2.0 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Lipase_GDSL PF00657.17 KFH48820.1 - 1.8e-08 34.5 4.0 1e-07 32.0 2.8 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KFH48820.1 - 1.1e-06 28.8 0.1 2.1e-06 28.0 0.1 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CMAS PF02353.15 KFH48821.1 - 6.5e-11 41.8 0.0 1.1e-10 41.0 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 KFH48821.1 - 1.7e-09 38.2 0.1 3.5e-09 37.2 0.1 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFH48821.1 - 1.2e-08 34.6 0.0 1.4e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH48821.1 - 7.1e-07 29.0 0.0 1.3e-06 28.2 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH48821.1 - 9.3e-06 26.0 0.0 1.5e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFH48821.1 - 3.9e-05 23.9 0.0 6.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH48821.1 - 0.00074 19.9 0.0 0.0012 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFH48821.1 - 0.0062 15.6 0.1 0.0088 15.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 KFH48821.1 - 0.028 13.7 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 KFH48821.1 - 0.035 14.1 1.2 0.093 12.7 0.8 1.9 1 1 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 KFH48821.1 - 0.048 13.0 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW FmrO PF07091.6 KFH48821.1 - 0.054 12.4 0.0 0.079 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Lactamase_B_2 PF12706.2 KFH48823.1 - 5.9e-33 114.0 0.1 1.3e-32 112.9 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 KFH48823.1 - 5.4e-20 70.6 0.3 3.9e-19 67.8 0.0 2.2 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.22 KFH48823.1 - 5.8e-09 35.8 0.1 2.2e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Cren7 PF11520.3 KFH48823.1 - 0.12 11.9 0.3 0.42 10.2 0.2 1.9 1 0 0 1 1 1 0 Chromatin protein Cren7 Pyr_redox_2 PF07992.9 KFH48824.1 - 2.8e-31 108.9 0.0 4.9e-31 108.1 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFH48824.1 - 4.7e-14 52.5 0.1 1.2e-10 41.6 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFH48824.1 - 3.1e-09 37.1 0.0 0.0067 16.5 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFH48824.1 - 0.0013 17.6 0.7 0.89 8.3 0.0 3.1 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 KFH48824.1 - 0.0077 16.2 0.1 2.3 8.2 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFH48824.1 - 0.013 14.4 0.5 7.7 5.3 0.0 3.4 4 0 0 4 4 4 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KFH48824.1 - 0.03 13.3 0.1 1.8 7.5 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain TPR_11 PF13414.1 KFH48825.1 - 2.6e-48 161.5 15.3 3.7e-22 77.7 2.3 5.8 4 2 1 5 5 5 4 TPR repeat TPR_2 PF07719.12 KFH48825.1 - 3.2e-38 126.5 7.5 7.3e-06 25.5 0.1 7.9 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.23 KFH48825.1 - 8.2e-36 120.1 6.2 2e-07 30.3 0.1 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.1 KFH48825.1 - 3.1e-28 97.8 8.6 1.6e-08 34.9 0.7 6.2 4 2 2 6 6 6 4 Tetratricopeptide repeat DnaJ PF00226.26 KFH48825.1 - 3.7e-26 90.6 1.6 1.1e-25 89.1 1.1 1.9 1 0 0 1 1 1 1 DnaJ domain TPR_19 PF14559.1 KFH48825.1 - 5.8e-26 90.6 15.9 7.8e-09 35.7 0.1 5.9 4 2 1 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.1 KFH48825.1 - 6.2e-24 82.3 11.2 0.00012 22.3 0.4 8.8 4 3 5 9 9 8 6 Tetratricopeptide repeat TPR_17 PF13431.1 KFH48825.1 - 8.7e-21 72.3 8.7 0.00041 20.3 0.0 6.3 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_12 PF13424.1 KFH48825.1 - 6.2e-18 64.5 10.6 5.7e-06 26.1 0.2 4.9 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 KFH48825.1 - 1.4e-15 55.7 11.1 0.042 13.6 0.2 7.7 6 1 2 8 8 7 4 Tetratricopeptide repeat Apc3 PF12895.2 KFH48825.1 - 1.2e-14 54.2 6.4 1.9e-07 31.1 0.2 3.8 3 1 2 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KFH48825.1 - 2.1e-13 49.9 3.3 2.6e-06 27.1 0.1 5.4 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFH48825.1 - 2e-11 42.7 4.1 0.11 12.3 0.0 6.7 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 KFH48825.1 - 6.4e-10 38.8 15.9 0.068 13.6 0.0 7.2 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_15 PF13429.1 KFH48825.1 - 3.3e-09 36.1 7.8 0.0005 19.2 0.9 4.5 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 KFH48825.1 - 1e-06 28.5 3.0 0.6 10.6 0.0 4.6 5 0 0 5 5 3 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 KFH48825.1 - 8.4e-06 26.0 5.9 0.11 12.7 0.0 4.5 2 2 2 4 4 4 2 Alkyl sulfatase dimerisation NARP1 PF12569.3 KFH48825.1 - 0.00011 21.1 2.9 1.1 7.9 0.1 4.4 3 2 2 5 5 5 1 NMDA receptor-regulated protein 1 BTAD PF03704.12 KFH48825.1 - 0.00046 20.5 11.0 0.27 11.5 0.6 5.1 3 2 1 5 5 5 1 Bacterial transcriptional activator domain TPR_20 PF14561.1 KFH48825.1 - 0.00047 20.2 6.2 0.26 11.4 0.1 4.8 2 2 4 6 6 6 1 Tetratricopeptide repeat DUF3808 PF10300.4 KFH48825.1 - 0.0012 17.4 0.5 0.064 11.8 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3808) MIT PF04212.13 KFH48825.1 - 0.0028 17.4 2.8 0.5 10.2 0.1 3.7 3 1 0 3 3 2 1 MIT (microtubule interacting and transport) domain NatB_MDM20 PF09797.4 KFH48825.1 - 0.011 14.4 0.1 0.026 13.2 0.0 1.6 2 0 0 2 2 2 0 N-acetyltransferase B complex (NatB) non catalytic subunit ChAPs PF09295.5 KFH48825.1 - 0.023 13.4 1.4 0.11 11.2 0.0 2.4 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) Coatomer_E PF04733.9 KFH48825.1 - 0.024 13.8 3.5 0.4 9.8 0.0 3.0 2 1 2 4 4 4 0 Coatomer epsilon subunit TPR_10 PF13374.1 KFH48825.1 - 0.11 12.4 14.5 16 5.5 0.6 6.1 6 1 1 7 7 6 0 Tetratricopeptide repeat Sel1 PF08238.7 KFH48825.1 - 0.16 12.6 2.1 9.7 6.9 0.0 3.8 2 1 1 3 3 2 0 Sel1 repeat Fis1_TPR_C PF14853.1 KFH48825.1 - 0.16 11.8 12.0 14 5.6 0.1 5.3 5 1 1 6 6 4 0 Fis1 C-terminal tetratricopeptide repeat YfiO PF13525.1 KFH48825.1 - 0.19 11.2 11.3 0.05 13.0 1.0 2.8 3 0 0 3 3 3 0 Outer membrane lipoprotein SHNi-TPR PF10516.4 KFH48825.1 - 1.4 8.2 5.9 16 4.8 0.1 3.9 4 0 0 4 4 4 0 SHNi-TPR DUF3366 PF11846.3 KFH48825.1 - 6.6 6.5 5.3 8.5 6.2 1.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3366) ERG4_ERG24 PF01222.12 KFH48826.1 - 5.4e-162 539.2 2.4 6.1e-162 539.0 1.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 KFH48826.1 - 0.0013 18.0 1.7 0.0026 17.0 1.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) TruD PF01142.13 KFH48827.1 - 9e-53 179.2 0.0 4.6e-49 167.0 0.0 3.7 3 1 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) Steroid_dh PF02544.11 KFH48829.1 - 6.3e-17 61.7 0.1 1.1e-16 60.9 0.1 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase zf-C2H2 PF00096.21 KFH48830.1 - 1e-05 25.5 3.7 1e-05 25.5 2.6 4.6 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFH48830.1 - 8.1e-05 22.7 4.4 8.1e-05 22.7 3.0 3.7 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFH48830.1 - 0.00032 20.7 1.0 0.0011 19.0 0.7 2.0 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KFH48830.1 - 0.00047 20.2 1.1 0.00047 20.2 0.8 4.3 4 0 0 4 4 4 1 C2H2-type zinc finger zf-met PF12874.2 KFH48830.1 - 0.067 13.4 2.3 0.15 12.3 0.6 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-TRAF PF02176.13 KFH48830.1 - 0.29 11.5 6.3 0.08 13.3 2.0 1.8 2 0 0 2 2 2 0 TRAF-type zinc finger zf-C2HC_2 PF13913.1 KFH48830.1 - 5 6.9 6.5 1.2 8.9 1.1 2.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type WW PF00397.21 KFH48831.1 - 4.5e-05 23.2 2.7 9.9e-05 22.1 1.9 1.6 1 0 0 1 1 1 1 WW domain CorA PF01544.13 KFH48832.1 - 7.2e-08 31.8 0.0 1.5e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF4381 PF14316.1 KFH48832.1 - 0.053 13.6 0.6 0.53 10.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF2231 PF09990.4 KFH48832.1 - 0.091 13.1 0.1 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) Helicase_C_3 PF13625.1 KFH48833.1 - 2.4e-26 92.0 0.0 1.2e-24 86.5 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFH48833.1 - 2.5e-14 53.5 0.0 5.6e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KFH48833.1 - 1.5e-10 40.3 0.0 2.3e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFH48833.1 - 1.6e-10 40.6 0.0 3.7e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Anillin PF08174.6 KFH48834.1 - 5.4e-33 114.0 0.2 2.5e-32 111.8 0.1 2.2 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 KFH48834.1 - 1.5e-09 37.9 0.0 5.7e-09 36.1 0.0 2.0 1 0 0 1 1 1 1 PH domain Metallophos PF00149.23 KFH48835.1 - 5.9e-45 153.1 0.2 7.1e-45 152.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2285 PF10074.4 KFH48836.1 - 0.097 13.0 0.1 0.34 11.2 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2285) Cys_rich_CPCC PF14206.1 KFH48836.1 - 0.097 12.2 0.2 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 Cysteine-rich CPCC Anemone_cytotox PF06369.7 KFH48836.1 - 0.2 11.0 0.0 0.48 9.8 0.0 1.5 1 0 0 1 1 1 0 Sea anemone cytotoxic protein Hat1_N PF10394.4 KFH48837.1 - 7.1e-36 123.7 0.0 1.2e-35 122.9 0.0 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.19 KFH48837.1 - 0.0028 17.6 0.0 0.016 15.2 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KFH48837.1 - 0.0075 16.3 0.0 0.041 14.0 0.0 2.3 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KFH48837.1 - 0.029 14.5 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain XPC-binding PF09280.6 KFH48838.1 - 2.3e-24 84.6 11.0 4.2e-24 83.7 7.6 1.4 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.26 KFH48838.1 - 1.8e-19 68.9 7.3 1.5e-09 37.4 0.2 2.7 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.18 KFH48838.1 - 1.8e-18 65.6 0.4 2.9e-18 65.0 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KFH48838.1 - 2e-08 33.7 0.2 3.9e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.5 KFH48838.1 - 0.0016 17.9 0.0 1.8 8.1 0.0 2.3 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain DUF2407 PF10302.4 KFH48838.1 - 0.0087 16.2 0.0 0.022 14.9 0.0 1.8 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain eIF-5a PF01287.15 KFH48838.1 - 0.013 15.4 0.3 0.04 13.8 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Rad60-SLD_2 PF13881.1 KFH48838.1 - 0.018 14.8 0.0 0.046 13.6 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like MCM_N PF14551.1 KFH48838.1 - 0.022 15.2 0.0 0.052 14.0 0.0 1.6 1 0 0 1 1 1 0 MCM N-terminal domain MSA-2c PF12238.3 KFH48838.1 - 0.043 13.4 0.4 0.043 13.4 0.3 2.2 3 0 0 3 3 3 0 Merozoite surface antigen 2c FAD_binding_4 PF01565.18 KFH48839.1 - 4.7e-25 87.6 0.6 1.1e-24 86.4 0.4 1.7 2 0 0 2 2 2 1 FAD binding domain Proteasome PF00227.21 KFH48840.1 - 1.5e-54 184.2 0.0 2.2e-54 183.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KFH48840.1 - 1.8e-12 46.3 0.1 1.8e-12 46.3 0.1 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RbsD_FucU PF05025.8 KFH48840.1 - 0.14 12.4 0.5 0.23 11.7 0.3 1.3 1 0 0 1 1 1 0 RbsD / FucU transport protein family Ubiq_cyt_C_chap PF03981.7 KFH48841.1 - 4.2e-36 123.8 0.2 1.3e-35 122.2 0.1 1.8 2 0 0 2 2 2 1 Ubiquinol-cytochrome C chaperone RicinB_lectin_2 PF14200.1 KFH48842.1 - 1.9e-06 28.1 0.1 6.3e-06 26.5 0.0 2.0 2 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like SKG6 PF08693.5 KFH48842.1 - 0.00033 19.9 0.3 0.00067 18.9 0.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Herpes_gE PF02480.11 KFH48842.1 - 0.012 13.9 0.0 0.018 13.3 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Rax2 PF12768.2 KFH48842.1 - 0.071 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Chlor_dismutase PF06778.7 KFH48842.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Chlorite dismutase Amidase PF01425.16 KFH48842.1 - 0.17 10.7 7.5 0.29 9.9 5.2 1.3 1 0 0 1 1 1 0 Amidase Acetyltransf_1 PF00583.19 KFH48843.1 - 0.0005 20.0 0.0 0.0016 18.4 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KFH48843.1 - 0.00091 19.3 0.0 0.0019 18.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KFH48843.1 - 0.0023 18.0 0.0 0.0043 17.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KFH48843.1 - 0.027 14.6 0.0 0.11 12.6 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFH48843.1 - 0.06 13.2 0.1 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 KFH48843.1 - 0.16 11.7 0.0 0.37 10.5 0.0 1.6 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Scs3p PF10261.4 KFH48844.1 - 1.6e-61 207.4 8.4 2e-61 207.0 5.8 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM BMC PF00936.14 KFH48844.1 - 0.025 14.2 0.0 0.063 12.9 0.0 1.6 1 0 0 1 1 1 0 BMC domain PHD PF00628.24 KFH48845.1 - 8.3e-10 38.2 7.1 8.3e-10 38.2 4.9 2.6 2 1 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.1 KFH48845.1 - 9.3e-08 31.7 3.4 9.3e-08 31.7 2.4 4.2 3 1 1 4 4 4 1 Ring finger domain PHD_2 PF13831.1 KFH48845.1 - 1.2e-07 30.8 1.6 1.2e-07 30.8 1.1 2.0 2 0 0 2 2 1 1 PHD-finger zf-rbx1 PF12678.2 KFH48845.1 - 7.7e-06 25.9 19.8 7.6e-05 22.7 5.1 3.1 2 2 0 2 2 2 2 RING-H2 zinc finger zf-Apc11 PF12861.2 KFH48845.1 - 0.00011 21.9 12.1 0.0025 17.6 0.7 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 KFH48845.1 - 0.0002 21.0 3.2 0.0002 21.0 2.2 3.7 4 0 0 4 4 4 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KFH48845.1 - 0.0011 18.5 2.7 0.0011 18.5 1.9 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFH48845.1 - 0.0026 17.3 3.0 0.0026 17.3 2.1 3.9 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 KFH48845.1 - 0.0028 17.3 2.9 0.0028 17.3 2.0 2.5 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 zf-C3HC4_2 PF13923.1 KFH48845.1 - 0.0052 16.7 3.8 0.0052 16.7 2.6 4.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 KFH48845.1 - 1.5 8.4 8.3 0.31 10.6 1.8 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Lectin_leg-like PF03388.8 KFH48846.1 - 1.1e-60 204.6 0.1 1.5e-60 204.2 0.1 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 KFH48846.1 - 1.6e-05 24.3 0.0 0.00018 20.9 0.0 2.0 1 1 0 1 1 1 1 Legume lectin domain CH PF00307.26 KFH48847.1 - 1.5e-40 137.5 0.2 2.4e-19 69.3 0.0 2.7 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 KFH48847.1 - 1.2e-29 102.0 1.1 4.1e-27 93.9 0.1 2.8 2 0 0 2 2 2 2 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 KFH48847.1 - 1.5e-13 50.2 0.4 1.5e-07 30.9 0.0 2.9 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_6 PF13405.1 KFH48847.1 - 0.0003 20.4 0.6 0.0078 16.0 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain Spectrin PF00435.16 KFH48847.1 - 0.002 18.3 7.9 0.51 10.6 3.3 2.8 2 0 0 2 2 2 2 Spectrin repeat EF-hand_8 PF13833.1 KFH48847.1 - 0.004 16.7 0.5 0.1 12.2 0.1 2.8 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 KFH48847.1 - 0.039 13.2 0.2 0.5 9.7 0.0 2.6 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.1 KFH48847.1 - 0.14 12.3 5.2 0.089 12.9 1.5 2.4 2 0 0 2 2 2 0 EF-hand domain pair G-gamma PF00631.17 KFH48848.1 - 1.3e-26 92.1 0.0 1.6e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 GGL domain DEAD PF00270.24 KFH48849.1 - 7.3e-41 139.4 0.0 2.1e-40 138.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFH48849.1 - 3.9e-27 93.9 0.1 1.9e-26 91.7 0.1 2.2 1 1 1 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KFH48849.1 - 8.5e-06 24.7 0.0 1.3e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KFH48849.1 - 0.0018 18.1 0.0 0.0053 16.5 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C2H2_4 PF13894.1 KFH48850.1 - 7.7e-29 97.8 46.4 0.0055 16.9 0.1 10.3 10 0 0 10 10 10 9 C2H2-type zinc finger zf-C2H2 PF00096.21 KFH48850.1 - 7.9e-28 95.0 52.0 9.4e-06 25.6 0.7 10.4 10 1 0 10 10 10 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFH48850.1 - 1e-12 47.6 54.7 0.0002 21.4 0.3 10.7 12 0 0 12 12 12 5 Zinc-finger double domain zf-met PF12874.2 KFH48850.1 - 5.5e-05 23.2 10.1 1.3 9.3 0.0 6.8 6 0 0 6 6 6 2 Zinc-finger of C2H2 type DUF4187 PF13821.1 KFH48850.1 - 0.0017 17.8 0.2 0.0062 16.1 0.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) zf-H2C2_5 PF13909.1 KFH48850.1 - 0.012 15.7 0.8 0.012 15.7 0.5 9.4 10 0 0 10 10 10 0 C2H2-type zinc-finger domain BolA PF01722.13 KFH48850.1 - 0.3 11.0 2.2 8.7 6.3 0.5 2.7 2 0 0 2 2 2 0 BolA-like protein IBR PF01485.16 KFH48850.1 - 0.34 10.8 23.9 0.84 9.5 2.4 5.0 2 2 1 3 3 3 0 IBR domain zf-C2H2_jaz PF12171.3 KFH48850.1 - 1.6 9.0 33.8 7.8 6.7 0.0 8.9 11 0 0 11 11 11 0 Zinc-finger double-stranded RNA-binding CHORD PF04968.7 KFH48850.1 - 7.5 6.8 22.8 6.5 7.0 0.6 6.3 4 2 3 7 7 7 0 CHORD Fungal_trans PF04082.13 KFH48851.1 - 1.1e-05 24.4 0.5 2.1e-05 23.5 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH48851.1 - 0.016 15.1 1.4 0.034 14.0 0.9 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Man-6-P_recep PF02157.10 KFH48853.1 - 2.3e-08 33.4 0.0 3.5e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.13 KFH48853.1 - 3.6e-08 33.2 0.1 0.00018 21.3 0.0 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.5 KFH48853.1 - 4.1e-05 22.9 0.3 0.00018 20.8 0.2 2.1 1 1 0 1 1 1 1 Autophagy-related protein 27 GCV_T PF01571.16 KFH48854.1 - 2.7e-14 53.0 0.0 3.8e-13 49.2 0.0 2.2 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain Toxin_61 PF15538.1 KFH48854.1 - 0.0036 17.3 0.0 0.29 11.1 0.0 2.5 2 1 0 2 2 2 1 Putative toxin 61 GCV_T_C PF08669.6 KFH48854.1 - 0.0037 17.2 0.0 0.0068 16.4 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain ICMT PF04140.9 KFH48855.1 - 3.3e-28 97.7 0.2 7.3e-28 96.6 0.1 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KFH48855.1 - 3.8e-11 43.0 0.6 3.8e-11 43.0 0.4 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 KFH48855.1 - 0.0071 15.6 0.1 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Zn_clus PF00172.13 KFH48856.1 - 7.7e-09 35.3 13.6 7.7e-09 35.3 9.5 2.0 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFH48856.1 - 0.0017 17.3 0.0 0.0024 16.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_16 PF13432.1 KFH48856.1 - 0.0062 17.1 1.2 0.016 15.8 0.8 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat Aminotran_1_2 PF00155.16 KFH48857.1 - 6e-83 278.7 0.0 9.5e-83 278.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KFH48857.1 - 7e-05 21.7 0.0 0.00011 21.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 KFH48857.1 - 8.3e-05 21.0 0.0 0.00013 20.4 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KFH48857.1 - 0.068 12.2 0.2 0.13 11.2 0.1 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family CPSF_A PF03178.10 KFH48858.1 - 3.7e-95 318.6 0.0 1.8e-94 316.4 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 KFH48858.1 - 2.9e-67 226.9 0.0 5.1e-67 226.1 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term WD40 PF00400.27 KFH48858.1 - 0.042 13.7 0.1 0.19 11.6 0.0 2.2 1 0 0 1 1 1 0 WD domain, G-beta repeat ECH PF00378.15 KFH48859.1 - 3.3e-71 239.2 0.1 4.1e-71 238.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family MotA_activ PF09114.5 KFH48859.1 - 0.038 13.7 0.1 2.6 7.8 0.1 2.2 2 0 0 2 2 2 0 Transcription factor MotA, activation domain Peptidase_S49 PF01343.13 KFH48859.1 - 0.072 12.8 0.0 0.2 11.4 0.0 1.7 2 0 0 2 2 2 0 Peptidase family S49 EF-hand_6 PF13405.1 KFH48860.1 - 3.7e-12 45.0 0.4 1.6e-05 24.3 0.0 2.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 KFH48860.1 - 1.6e-09 37.7 1.1 1.6e-06 28.1 0.2 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KFH48860.1 - 1.2e-08 33.5 2.5 0.0025 17.0 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 KFH48860.1 - 5.6e-07 28.6 5.5 0.00059 19.0 0.3 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KFH48860.1 - 1.6e-05 24.4 0.7 0.052 13.1 0.0 2.9 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.1 KFH48860.1 - 0.0083 16.0 0.0 0.39 10.6 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain DPM2 PF07297.7 KFH48861.1 - 1.9e-32 111.3 1.9 2.2e-32 111.1 1.3 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 KFH48861.1 - 0.00012 21.7 0.8 0.00012 21.6 0.6 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.1 KFH48861.1 - 0.0014 18.5 0.5 0.0014 18.5 0.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) DUF4083 PF13314.1 KFH48861.1 - 0.0084 15.9 0.1 0.0084 15.9 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4083) DUF1049 PF06305.6 KFH48861.1 - 0.053 13.0 0.2 0.053 13.0 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Herpes_UL43 PF05072.8 KFH48861.1 - 0.12 11.0 0.5 0.14 10.9 0.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL43 protein DiS_P_DiS PF06750.8 KFH48861.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain COX14 PF14880.1 KFH48861.1 - 0.25 10.9 1.5 0.34 10.5 0.0 1.8 2 0 0 2 2 2 0 Cytochrome oxidase c assembly ADH_N PF08240.7 KFH48862.1 - 8e-26 89.9 6.2 1.4e-25 89.1 4.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFH48862.1 - 4.1e-15 55.4 0.0 1.5e-14 53.6 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KFH48862.1 - 0.0015 17.6 0.2 0.0027 16.8 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain hGDE_central PF14702.1 KFH48864.1 - 0.043 13.0 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 central domain of human glycogen debranching enzyme WD40 PF00400.27 KFH48865.1 - 5.3e-47 156.1 20.2 3e-08 33.2 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KFH48865.1 - 0.00023 20.9 0.0 0.053 13.2 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A DHFR_1 PF00186.14 KFH48866.1 - 5.6e-32 110.5 0.0 3e-31 108.1 0.0 2.2 1 1 0 1 1 1 1 Dihydrofolate reductase DSBA PF01323.15 KFH48866.1 - 2.3e-15 56.6 0.0 3.7e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Nnf1 PF03980.9 KFH48867.1 - 1.4e-27 95.8 0.2 3.9e-27 94.4 0.1 1.7 2 0 0 2 2 2 1 Nnf1 Sulfotransfer_3 PF13469.1 KFH48867.1 - 0.025 15.5 1.5 0.037 14.9 1.0 1.3 1 1 0 1 1 1 0 Sulfotransferase family HAUS6_N PF14661.1 KFH48867.1 - 0.08 12.2 0.8 0.36 10.1 0.5 1.9 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus GrpE PF01025.14 KFH48867.1 - 0.11 12.0 1.1 0.18 11.3 0.8 1.3 1 0 0 1 1 1 0 GrpE Apolipoprotein PF01442.13 KFH48867.1 - 0.2 11.1 6.7 0.25 10.8 3.5 1.8 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Arrestin_N PF00339.24 KFH48868.1 - 0.00067 19.5 0.1 0.047 13.5 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Methyltransf_31 PF13847.1 KFH48869.1 - 4.6e-08 32.8 0.0 6.9e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFH48869.1 - 4.7e-08 32.9 0.0 7.2e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFH48869.1 - 2.2e-07 31.2 0.0 7.7e-07 29.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFH48869.1 - 4.1e-07 30.2 0.0 7.5e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFH48869.1 - 5.6e-06 26.9 0.0 9.2e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFH48869.1 - 8.8e-06 24.9 0.0 0.00032 19.8 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KFH48869.1 - 0.0001 22.3 0.0 0.0002 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFH48869.1 - 0.0003 21.2 0.0 0.00056 20.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFH48869.1 - 0.12 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.12 KFH48869.1 - 0.15 11.0 0.1 17 4.3 0.0 2.4 2 0 0 2 2 2 0 Putative methyltransferase DUF4602 PF15375.1 KFH48870.1 - 1.7e-05 24.8 6.1 1.7e-05 24.8 4.2 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4602) Daxx PF03344.10 KFH48870.1 - 0.017 13.6 18.4 0.021 13.3 12.8 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 KFH48870.1 - 0.18 9.6 21.2 0.32 8.8 14.7 1.3 1 0 0 1 1 1 0 Nop14-like family PI3K_1B_p101 PF10486.4 KFH48870.1 - 0.59 7.6 3.5 0.64 7.5 2.5 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF2040 PF09745.4 KFH48871.1 - 6.8e-40 135.8 16.2 6.8e-40 135.8 11.2 2.9 3 0 0 3 3 3 2 Coiled-coil domain-containing protein 55 (DUF2040) Ank_2 PF12796.2 KFH48872.1 - 5.6e-25 87.5 0.0 1.7e-16 60.2 0.1 2.7 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFH48872.1 - 7.7e-19 66.4 5.0 4.6e-08 32.4 0.1 5.8 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 KFH48872.1 - 1.5e-15 56.8 7.2 1.6e-07 31.3 0.1 5.1 3 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFH48872.1 - 4.6e-13 49.2 0.1 2e-08 34.5 0.1 4.3 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFH48872.1 - 7.2e-12 44.3 0.1 2.2e-05 24.2 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat E1-E2_ATPase PF00122.15 KFH48874.1 - 6.4e-20 71.1 0.1 1.2e-19 70.3 0.1 1.4 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KFH48874.1 - 1.7e-19 70.7 0.2 4.3e-19 69.4 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFH48874.1 - 1.6e-13 51.6 2.7 1.1e-11 45.5 1.8 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFH48874.1 - 1.1e-11 44.5 0.0 3.1e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFH48874.1 - 0.002 17.7 0.3 0.0055 16.3 0.2 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KFH48874.1 - 0.056 13.6 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase PH_9 PF15410.1 KFH48875.1 - 8.7e-08 32.3 0.0 1.5e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KFH48875.1 - 1.6e-07 31.4 0.0 2.7e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 PH domain DUF2587 PF10759.4 KFH48875.1 - 0.032 13.6 0.4 0.2 11.0 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2587) Saccharop_dh PF03435.13 KFH48876.1 - 8.1e-20 71.1 0.0 1.2e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 KFH48876.1 - 0.0027 17.9 0.0 0.0086 16.3 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KFH48876.1 - 0.071 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 KFH48878.1 - 3.4e-17 62.8 0.0 4.8e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH48878.1 - 1.7e-05 24.5 0.0 3.1e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFH48878.1 - 1.9e-05 24.5 0.0 2.3e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KFH48878.1 - 0.014 14.5 0.0 1.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KFH48878.1 - 0.02 14.9 0.2 0.056 13.4 0.2 1.9 1 1 0 1 1 1 0 NADH(P)-binding SSB PF00436.20 KFH48879.1 - 5.7e-19 67.9 0.0 6.9e-19 67.6 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Stm1_N PF09598.5 KFH48880.1 - 2.1e-09 37.9 0.8 2.1e-09 37.9 0.5 4.4 4 1 1 5 5 5 1 Stm1 HABP4_PAI-RBP1 PF04774.10 KFH48880.1 - 3.3e-05 24.3 6.5 3.3e-05 24.3 4.5 3.2 4 1 0 4 4 4 1 Hyaluronan / mRNA binding family TGS PF02824.16 KFH48881.1 - 2e-18 65.9 0.1 4.1e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 KFH48881.1 - 1.1e-17 64.1 0.0 2.2e-17 63.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFH48881.1 - 2.5e-09 36.6 0.1 1.2e-08 34.3 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KFH48881.1 - 0.00011 21.7 0.3 1.3 8.3 0.0 3.9 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KFH48881.1 - 0.00029 20.7 0.0 0.077 12.8 0.0 2.5 2 0 0 2 2 2 1 Dynamin family Miro PF08477.8 KFH48881.1 - 0.0015 19.0 0.0 0.015 15.7 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein Pga1 PF10333.4 KFH48881.1 - 0.0073 15.9 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 GPI-Mannosyltransferase II co-activator ArgK PF03308.11 KFH48881.1 - 0.0075 15.0 0.1 0.019 13.7 0.1 1.6 1 0 0 1 1 1 1 ArgK protein AIG1 PF04548.11 KFH48881.1 - 0.094 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 AIG1 family CBS PF00571.23 KFH48881.1 - 0.1 12.4 0.1 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 CBS domain M PF02370.11 KFH48881.1 - 6.1 7.5 5.4 32 5.3 0.3 2.8 2 0 0 2 2 2 0 M protein repeat DUF543 PF04418.7 KFH48882.1 - 2.7e-27 94.4 0.0 2.9e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Pinin_SDK_memA PF04696.8 KFH48883.1 - 9.7e-27 93.1 14.0 1.6e-26 92.4 9.7 1.4 1 0 0 1 1 1 1 pinin/SDK/memA/ protein conserved region CAP_N PF01213.14 KFH48883.1 - 0.03 13.6 5.0 0.055 12.7 3.4 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Fzo_mitofusin PF04799.8 KFH48883.1 - 2.9 7.2 5.5 4.2 6.7 3.8 1.2 1 0 0 1 1 1 0 fzo-like conserved region DUF106 PF01956.11 KFH48883.1 - 2.9 7.3 6.3 5.1 6.5 4.4 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF106 Dus PF01207.12 KFH48884.1 - 1.2e-61 208.3 0.0 1.7e-61 207.7 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DUF849 PF05853.7 KFH48884.1 - 0.13 11.1 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic protein of unknown function (DUF849) DUF155 PF02582.9 KFH48885.1 - 9.5e-58 194.9 0.6 1.3e-57 194.5 0.4 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF3535 PF12054.3 KFH48886.1 - 6.8e-144 479.7 1.3 3.8e-143 477.3 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 KFH48886.1 - 1.9e-74 250.1 0.0 3.4e-74 249.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 KFH48886.1 - 4.7e-19 66.6 1.9 0.017 15.1 0.0 8.2 7 0 0 7 7 7 6 HEAT repeat Helicase_C PF00271.26 KFH48886.1 - 3.4e-14 52.4 0.0 8.8e-14 51.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Vac14_Fab1_bd PF12755.2 KFH48886.1 - 2.2e-07 31.1 0.2 0.82 10.1 0.0 3.9 2 1 1 3 3 3 3 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 KFH48886.1 - 2.7e-05 24.3 12.4 0.045 14.0 0.0 6.9 7 2 2 9 9 9 1 HEAT repeats HEAT_EZ PF13513.1 KFH48886.1 - 3.1e-05 24.2 7.3 30 5.2 0.0 8.4 8 0 0 8 8 8 0 HEAT-like repeat CLASP_N PF12348.3 KFH48886.1 - 0.0014 18.0 0.2 1 8.6 0.0 3.8 3 1 1 4 4 4 1 CLASP N terminal WD40 PF00400.27 KFH48887.1 - 1.9e-07 30.6 9.8 0.00048 19.8 0.0 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat TruB_C PF09142.6 KFH48887.1 - 0.013 15.1 2.4 0.69 9.6 0.0 3.9 4 0 0 4 4 4 0 tRNA Pseudouridine synthase II, C terminal PD40 PF07676.7 KFH48887.1 - 0.033 13.8 1.3 0.52 10.0 0.1 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF1652 PF07865.6 KFH48887.1 - 0.078 12.5 0.0 7.8 6.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1652) DUF2457 PF10446.4 KFH48888.1 - 1.1e-129 433.1 39.2 1.1e-129 433.1 27.2 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2457) Nop14 PF04147.7 KFH48888.1 - 0.047 11.6 36.6 0.02 12.8 22.0 2.0 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.9 KFH48888.1 - 0.53 8.2 30.2 0.12 10.3 14.3 2.2 2 0 0 2 2 2 0 CDC45-like protein Synaptobrevin PF00957.16 KFH48890.1 - 2.4e-06 27.0 6.6 0.052 13.1 0.1 4.2 1 1 2 4 4 4 3 Synaptobrevin Laminin_I PF06008.9 KFH48890.1 - 1.1e-05 24.9 8.5 0.007 15.7 5.5 2.8 1 1 1 2 2 2 1 Laminin Domain I DUF4337 PF14235.1 KFH48890.1 - 5.1e-05 23.1 0.7 5.1e-05 23.1 0.5 2.8 1 1 2 3 3 3 1 Domain of unknown function (DUF4337) Vfa1 PF08432.5 KFH48890.1 - 0.00037 20.5 5.5 0.0011 19.0 0.5 2.0 1 1 1 2 2 2 1 AAA-ATPase Vps4-associated protein 1 Laminin_II PF06009.7 KFH48890.1 - 0.0017 18.1 3.8 0.0092 15.7 0.1 2.2 1 1 1 2 2 2 2 Laminin Domain II BLOC1_2 PF10046.4 KFH48890.1 - 0.0033 17.5 5.4 0.28 11.3 2.0 3.0 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-F_leu_zip PF10473.4 KFH48890.1 - 0.0039 17.0 14.2 0.042 13.6 0.9 2.2 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2935 PF11155.3 KFH48890.1 - 0.0045 17.0 2.4 0.053 13.6 0.1 2.6 1 1 1 2 2 2 1 Domain of unknown function (DUF2935) Tropomyosin_1 PF12718.2 KFH48890.1 - 0.011 15.6 8.5 0.011 15.6 5.9 2.1 1 1 1 2 2 2 0 Tropomyosin like Gp-FAR-1 PF05823.7 KFH48890.1 - 0.017 15.0 5.3 0.072 13.0 1.3 2.7 1 1 2 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF904 PF06005.7 KFH48890.1 - 0.03 14.6 0.4 0.03 14.6 0.3 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF904) DUF948 PF06103.6 KFH48890.1 - 0.03 14.1 2.2 0.51 10.2 0.1 2.9 3 1 0 3 3 2 0 Bacterial protein of unknown function (DUF948) ERM PF00769.14 KFH48890.1 - 0.039 13.5 14.1 0.01 15.3 3.5 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Nup88 PF10168.4 KFH48890.1 - 0.039 11.8 0.2 0.039 11.8 0.1 2.3 1 1 2 3 3 3 0 Nuclear pore component DUF3540 PF12059.3 KFH48890.1 - 0.042 13.5 0.2 0.063 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3540) Jnk-SapK_ap_N PF09744.4 KFH48890.1 - 0.048 13.6 1.0 0.048 13.6 0.7 2.9 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 PMC2NT PF08066.7 KFH48890.1 - 0.049 13.9 3.6 1.4 9.2 0.7 3.0 1 1 1 2 2 2 0 PMC2NT (NUC016) domain DUF3552 PF12072.3 KFH48890.1 - 0.056 12.6 12.0 3.8 6.6 8.3 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) GldM_N PF12081.3 KFH48890.1 - 0.078 12.5 2.5 0.3 10.6 1.6 2.0 1 1 1 2 2 2 0 GldM N-terminal domain NPV_P10 PF05531.7 KFH48890.1 - 0.094 12.9 3.9 1.8 8.8 0.3 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Sipho_Gp157 PF05565.6 KFH48890.1 - 0.1 12.1 8.7 0.072 12.6 2.7 2.4 1 1 0 2 2 2 0 Siphovirus Gp157 UPF0449 PF15136.1 KFH48890.1 - 0.13 12.4 7.4 1.3 9.3 0.4 3.2 1 1 2 3 3 3 0 Uncharacterised protein family UPF0449 Snapin_Pallidin PF14712.1 KFH48890.1 - 0.17 12.2 3.0 0.55 10.5 1.1 2.2 1 1 1 2 2 2 0 Snapin/Pallidin CCDC155 PF14662.1 KFH48890.1 - 0.17 11.4 14.2 0.17 11.4 5.4 2.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 bZIP_1 PF00170.16 KFH48890.1 - 0.24 11.3 0.2 0.24 11.3 0.2 3.5 2 1 1 3 3 3 0 bZIP transcription factor Mnd1 PF03962.10 KFH48890.1 - 0.25 10.9 8.3 0.26 10.9 0.9 2.1 1 1 1 2 2 2 0 Mnd1 family Spc7 PF08317.6 KFH48890.1 - 0.28 9.8 8.7 0.47 9.0 4.3 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF972 PF06156.8 KFH48890.1 - 0.28 11.5 7.8 2.6 8.4 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF972) EMP24_GP25L PF01105.19 KFH48890.1 - 0.36 10.5 5.4 2.9 7.5 0.4 2.9 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD V_ATPase_I PF01496.14 KFH48890.1 - 0.44 8.3 5.0 0.92 7.2 3.5 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3450 PF11932.3 KFH48890.1 - 0.59 9.3 6.2 0.68 9.1 1.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Sec34 PF04136.10 KFH48890.1 - 0.66 9.6 3.1 1.7 8.3 0.1 2.4 1 1 2 3 3 3 0 Sec34-like family CDC37_N PF03234.9 KFH48890.1 - 1.4 9.2 6.8 2.9 8.1 0.4 2.3 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding VSG_B PF13206.1 KFH48890.1 - 2 7.4 6.7 0.6 9.1 1.1 1.9 1 1 1 2 2 2 0 Trypanosomal VSG domain DUF3359 PF11839.3 KFH48890.1 - 2.1 8.7 8.8 3.8 7.9 0.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3359) TBPIP PF07106.8 KFH48890.1 - 2.2 7.8 6.4 1.8 8.0 2.4 2.2 1 1 3 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) WXG100 PF06013.7 KFH48890.1 - 2.4 8.2 5.4 11 6.1 1.1 2.8 1 1 1 2 2 2 0 Proteins of 100 residues with WXG DASH_Dad2 PF08654.5 KFH48890.1 - 2.5 8.1 6.9 7 6.7 0.4 3.3 1 1 2 4 4 4 0 DASH complex subunit Dad2 TMF_DNA_bd PF12329.3 KFH48890.1 - 6.4 6.6 13.0 0.28 11.0 0.7 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding ISG65-75 PF11727.3 KFH48890.1 - 7 5.6 9.7 1.4 7.9 2.9 1.9 1 1 0 2 2 2 0 Invariant surface glycoprotein APG6 PF04111.7 KFH48890.1 - 7.3 5.5 13.5 0.97 8.4 3.9 1.9 1 1 1 2 2 2 0 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 KFH48890.1 - 8.8 6.3 13.6 1.5 8.8 1.7 3.0 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain PXA PF02194.10 KFH48891.1 - 2.8e-36 124.8 0.4 5.2e-36 123.9 0.0 1.6 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 KFH48891.1 - 0.00044 20.3 0.0 0.0015 18.6 0.0 1.8 1 0 0 1 1 1 1 Sorting nexin C terminal PHD PF00628.24 KFH48892.1 - 2.7e-07 30.1 9.8 4.4e-07 29.4 6.8 1.4 1 0 0 1 1 1 1 PHD-finger PHD PF00628.24 KFH48893.1 - 1.8e-09 37.1 7.3 3e-09 36.4 5.0 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 KFH48893.1 - 0.05 13.8 0.0 0.14 12.4 0.0 1.8 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.1 KFH48893.1 - 0.17 12.0 1.3 0.34 11.0 0.9 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain SNF2_N PF00176.18 KFH48894.1 - 1.2e-82 277.0 0.5 1.2e-82 277.0 0.3 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 KFH48894.1 - 1.9e-19 69.3 0.2 5.5e-19 67.8 0.2 1.8 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 KFH48894.1 - 2e-18 65.9 0.3 2.7e-16 59.1 0.0 3.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SnAC PF14619.1 KFH48894.1 - 2.4e-17 62.8 2.5 2.4e-17 62.8 1.7 3.6 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 KFH48894.1 - 7.1e-14 51.3 13.6 7.1e-14 51.3 9.4 3.7 3 0 0 3 3 3 1 HSA QLQ PF08880.6 KFH48894.1 - 5.4e-11 41.7 4.3 5.4e-11 41.7 3.0 1.9 2 0 0 2 2 2 1 QLQ Paf1 PF03985.8 KFH48896.1 - 9.1e-62 209.2 6.7 1.2e-61 208.8 4.7 1.1 1 0 0 1 1 1 1 Paf1 ASC PF00858.19 KFH48896.1 - 0.015 13.9 0.1 0.018 13.7 0.0 1.2 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel NAD_binding_10 PF13460.1 KFH48897.1 - 1.7e-14 54.2 0.0 3.3e-13 50.0 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFH48897.1 - 4.5e-08 32.8 0.0 7.4e-08 32.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFH48897.1 - 7.9e-06 24.7 0.0 2e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KFH48897.1 - 0.00062 19.7 0.0 0.0019 18.1 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KFH48897.1 - 0.056 12.3 0.0 3.7 6.3 0.0 2.6 2 1 1 3 3 3 0 Male sterility protein RmlD_sub_bind PF04321.12 KFH48897.1 - 0.073 11.9 0.0 0.2 10.5 0.0 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain FMN_dh PF01070.13 KFH48898.1 - 3.1e-96 322.3 0.1 8.3e-95 317.6 0.1 2.0 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KFH48898.1 - 1.6e-07 30.5 0.1 2.7e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KFH48898.1 - 2.8e-06 26.4 1.2 0.0002 20.3 0.7 2.8 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 KFH48898.1 - 0.015 14.4 0.3 0.029 13.5 0.2 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase ThiG PF05690.9 KFH48898.1 - 0.075 12.1 0.1 0.76 8.7 0.0 2.5 3 0 0 3 3 3 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 KFH48898.1 - 0.15 11.3 0.3 0.37 10.0 0.0 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein DUF2347 PF09804.4 KFH48899.1 - 2.5e-106 355.0 0.0 3.7e-106 354.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 KFH48899.1 - 2.1e-48 164.7 0.1 2.1e-48 164.7 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4484) SPA PF08616.5 KFH48899.1 - 2.9e-07 30.1 0.0 8.5e-07 28.6 0.0 1.7 1 1 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 KFH48899.1 - 1.6e-06 26.8 0.0 0.0087 14.5 0.0 3.4 3 1 0 3 3 3 3 Transport protein Avl9 DEAD PF00270.24 KFH48900.1 - 3.8e-43 146.8 0.0 6.6e-43 146.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFH48900.1 - 4e-24 84.2 0.0 9.7e-24 83.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 KFH48900.1 - 0.0062 14.9 0.3 0.036 12.4 0.0 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF1253) Glyoxalase PF00903.20 KFH48900.1 - 0.077 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Cpn60_TCP1 PF00118.19 KFH48901.1 - 1.1e-138 462.9 1.5 1.3e-138 462.7 1.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TMP_2 PF06791.8 KFH48901.1 - 0.19 11.3 2.4 2.9 7.4 0.1 2.3 2 0 0 2 2 2 0 Prophage tail length tape measure protein ABM PF03992.11 KFH48902.1 - 1.2e-08 34.7 0.0 1.5e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase UCR_hinge PF02320.11 KFH48902.1 - 0.022 14.7 0.2 0.03 14.2 0.1 1.2 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein DUF1295 PF06966.7 KFH48903.1 - 2.1e-33 115.5 6.9 2.6e-33 115.2 4.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 KFH48903.1 - 0.0021 18.1 0.5 0.079 13.1 0.0 2.4 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DNase-RNase PF02577.9 KFH48904.1 - 0.046 12.9 0.1 0.091 11.9 0.1 1.5 1 0 0 1 1 1 0 Bifunctional nuclease Matrilin_ccoil PF10393.4 KFH48904.1 - 0.81 9.1 2.5 0.51 9.7 0.1 1.8 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Sugarporin_N PF11471.3 KFH48904.1 - 4.5 6.9 8.4 0.22 11.2 1.4 2.3 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension PhyH PF05721.8 KFH48905.1 - 0.00096 19.2 0.0 0.0054 16.7 0.0 2.1 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PI-PLC-X PF00388.14 KFH48906.1 - 6.8e-62 207.1 0.0 1e-61 206.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KFH48906.1 - 3.2e-38 130.3 0.0 6.2e-38 129.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KFH48906.1 - 0.0041 17.1 0.0 0.0083 16.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like NTF2 PF02136.15 KFH48908.1 - 2.7e-24 85.7 0.7 4.3e-24 85.1 0.5 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 KFH48908.1 - 7.5e-07 28.6 0.1 1.3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH48908.1 - 8.4e-06 25.6 0.0 1.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH48908.1 - 0.0014 18.4 0.0 0.0035 17.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFH48908.1 - 0.0058 16.4 0.2 0.016 15.0 0.0 1.8 2 0 0 2 2 2 1 RNA binding motif PAT1 PF09770.4 KFH48908.1 - 0.053 11.7 20.0 0.063 11.5 13.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4283 PF14111.1 KFH48908.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4283) Hydrolase_6 PF13344.1 KFH48909.1 - 1.8e-26 91.9 0.0 2.9e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFH48909.1 - 1.2e-10 40.8 0.0 2.5e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KFH48909.1 - 1.9e-10 41.5 0.0 6.8e-10 39.7 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KFH48909.1 - 1.2e-05 25.6 0.0 0.0096 16.1 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase MIF4G PF02854.14 KFH48910.1 - 9.6e-27 93.7 0.1 2.4e-26 92.4 0.1 1.7 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 KFH48910.1 - 8.5e-21 73.7 0.0 2.4e-20 72.3 0.0 1.8 1 0 0 1 1 1 1 MA3 domain FAM176 PF14851.1 KFH48910.1 - 0.42 10.2 4.5 0.89 9.2 3.2 1.5 1 0 0 1 1 1 0 FAM176 family TRAP_alpha PF03896.11 KFH48910.1 - 1.6 7.6 7.2 2.9 6.8 5.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.7 KFH48910.1 - 2.4 5.9 12.9 4 5.2 9.0 1.3 1 0 0 1 1 1 0 Nop14-like family DUF4045 PF13254.1 KFH48911.1 - 6.5e-76 256.2 52.4 1.4e-41 143.1 24.7 6.9 3 3 2 6 6 6 2 Domain of unknown function (DUF4045) Gelsolin PF00626.17 KFH48911.1 - 1.1e-11 44.2 0.0 0.01 15.5 0.0 3.9 3 0 0 3 3 3 3 Gelsolin repeat DUF919 PF06034.6 KFH48912.1 - 0.11 12.1 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) PX PF00787.19 KFH48913.1 - 4.2e-14 52.3 0.0 7.1e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 KFH48913.1 - 1.2e-11 44.1 3.9 2e-11 43.3 2.7 1.4 1 0 0 1 1 1 1 SNARE domain U3_snoRNA_assoc PF08297.6 KFH48914.1 - 4.8e-10 39.5 1.9 4.8e-10 39.5 1.3 2.8 2 1 0 2 2 2 1 U3 snoRNA associated CDC45 PF02724.9 KFH48914.1 - 0.00086 17.4 11.1 0.00086 17.4 7.7 1.8 1 1 0 2 2 2 1 CDC45-like protein Ycf1 PF05758.7 KFH48914.1 - 1.6 6.3 4.3 1.6 6.3 3.0 1.1 1 0 0 1 1 1 0 Ycf1 Muted PF14942.1 KFH48914.1 - 4 7.3 9.5 9 6.1 6.6 1.5 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DIOX_N PF14226.1 KFH48916.1 - 2.3e-22 79.6 0.1 4.6e-22 78.7 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KFH48916.1 - 3.6e-18 65.6 0.0 9.2e-18 64.3 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF2236 PF09995.4 KFH48917.1 - 9.9e-06 25.0 4.8 5.5e-05 22.5 3.3 2.2 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) adh_short PF00106.20 KFH48918.1 - 9.2e-23 80.9 0.0 1.4e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFH48918.1 - 1.7e-09 37.5 0.0 2.6e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFH48918.1 - 7.5e-09 35.7 0.0 1.1e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KFH48918.1 - 0.00011 22.2 0.0 0.0038 17.2 0.1 2.2 2 0 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KFH48918.1 - 0.00026 20.7 0.5 0.0005 19.8 0.3 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_7 PF13241.1 KFH48918.1 - 0.016 15.4 0.0 0.042 14.1 0.0 1.6 2 0 0 2 2 2 0 Putative NAD(P)-binding ADH_zinc_N PF00107.21 KFH48918.1 - 0.052 13.0 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Raptor_N PF14538.1 KFH48918.1 - 0.064 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain F420_oxidored PF03807.12 KFH48918.1 - 0.067 13.6 0.0 0.29 11.6 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Ku PF02735.11 KFH48919.1 - 9.7e-24 83.8 0.0 1.8e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 KFH48919.1 - 3.6e-23 82.1 0.0 5.8e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 KFH48919.1 - 4.1e-17 62.1 0.0 9.4e-17 61.0 0.0 1.6 1 0 0 1 1 1 1 Ku C terminal domain like VWA_2 PF13519.1 KFH48919.1 - 0.00017 21.7 1.1 0.00024 21.2 0.1 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 KFH48919.1 - 0.058 13.1 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain Peptidase_M18 PF02127.10 KFH48920.1 - 6.3e-163 542.2 0.0 1.1e-162 541.4 0.0 1.4 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 KFH48920.1 - 1.5e-05 23.9 0.0 0.00011 21.1 0.0 2.2 2 1 1 3 3 3 1 M42 glutamyl aminopeptidase Rotamase_3 PF13616.1 KFH48921.1 - 1.3e-17 64.1 0.1 1.9e-17 63.5 0.1 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 KFH48921.1 - 2.3e-17 63.4 0.1 3.3e-17 63.0 0.1 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 KFH48921.1 - 6e-06 26.8 0.1 7e-06 26.6 0.1 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain PTPLA PF04387.9 KFH48922.1 - 6.5e-54 181.7 5.7 1.1e-53 181.0 4.0 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA NMD3 PF04981.8 KFH48923.1 - 0.29 10.1 3.4 0.65 9.0 0.1 2.2 1 1 1 2 2 2 0 NMD3 family SelB-wing_2 PF09106.6 KFH48923.1 - 3 7.8 4.3 11 6.0 0.2 2.8 3 0 0 3 3 3 0 Elongation factor SelB, winged helix MFS_1 PF07690.11 KFH48924.1 - 2.7e-25 88.8 26.2 6.3e-13 48.1 2.7 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 KFH48924.1 - 1.5e-07 30.2 18.1 7.4e-07 27.9 1.3 3.9 3 1 0 3 3 3 2 MFS/sugar transport protein TraL PF07178.6 KFH48924.1 - 0.24 11.4 0.1 0.24 11.4 0.0 3.3 3 0 0 3 3 3 0 TraL protein SnoaL_4 PF13577.1 KFH48925.1 - 0.00014 21.7 0.3 0.00019 21.3 0.2 1.3 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.2 KFH48925.1 - 0.069 13.5 0.3 0.11 12.8 0.2 1.5 1 1 0 1 1 1 0 SnoaL-like domain YEATS PF03366.11 KFH48926.1 - 1.3e-27 95.2 0.2 2e-27 94.7 0.2 1.3 1 0 0 1 1 1 1 YEATS family DUF641 PF04859.7 KFH48926.1 - 0.011 15.4 0.5 0.017 14.8 0.3 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) CN_hydrolase PF00795.17 KFH48927.1 - 3e-30 104.9 0.1 4e-30 104.5 0.1 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DnaJ PF00226.26 KFH48928.1 - 3.7e-07 29.7 0.0 5.1e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 KFH48928.1 - 3.9e-07 29.8 0.0 4.2e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Pam16 DUF3918 PF13056.1 KFH48928.1 - 0.62 9.4 6.0 0.19 11.0 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) Pkinase PF00069.20 KFH48929.1 - 4.9e-59 199.5 0.0 7.2e-59 199.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH48929.1 - 3.3e-19 68.9 0.0 2.9e-18 65.9 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase DUF2075 PF09848.4 KFH48929.1 - 0.017 14.0 0.0 0.034 13.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) LRR_4 PF12799.2 KFH48930.1 - 1.4e-16 59.6 11.7 2.8e-06 26.7 2.0 5.6 3 1 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFH48930.1 - 3.5e-15 55.4 18.0 1.5e-08 34.2 2.1 3.5 3 1 2 5 5 5 3 Leucine rich repeat LRR_1 PF00560.28 KFH48930.1 - 1.5e-10 39.5 8.2 0.44 10.7 0.0 6.5 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 KFH48930.1 - 6.9e-05 22.4 11.1 22 5.8 0.2 6.6 7 0 0 7 7 7 2 Leucine rich repeat LRR_6 PF13516.1 KFH48930.1 - 0.00046 19.9 3.6 23 5.4 0.0 5.9 6 0 0 6 6 6 1 Leucine Rich repeat Hom_end PF05204.9 KFH48930.1 - 0.14 12.0 0.1 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Homing endonuclease AAA PF00004.24 KFH48931.1 - 4.2e-49 166.1 0.0 3.3e-42 143.8 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KFH48931.1 - 7.7e-07 28.6 0.0 4.2e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.1 KFH48931.1 - 8e-07 29.2 0.0 9e-05 22.5 0.1 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 KFH48931.1 - 1.2e-05 25.3 0.0 3.1e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KFH48931.1 - 2.6e-05 24.3 1.0 0.002 18.2 0.0 3.6 3 1 0 3 3 2 1 AAA domain AAA_17 PF13207.1 KFH48931.1 - 0.0011 19.8 1.4 0.024 15.4 0.0 3.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KFH48931.1 - 0.0018 18.0 0.0 0.0091 15.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KFH48931.1 - 0.0023 17.7 0.2 0.01 15.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KFH48931.1 - 0.0034 17.5 0.0 0.013 15.7 0.0 2.0 2 0 0 2 2 2 1 RNA helicase TIP49 PF06068.8 KFH48931.1 - 0.0058 15.3 0.0 0.01 14.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 KFH48931.1 - 0.0067 16.7 0.0 0.041 14.1 0.0 2.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KFH48931.1 - 0.0075 16.1 0.0 0.027 14.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KFH48931.1 - 0.011 15.3 0.1 0.16 11.6 0.1 2.7 2 1 0 2 2 2 0 NACHT domain RuvB_N PF05496.7 KFH48931.1 - 0.012 14.6 0.0 0.027 13.5 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Sigma54_activ_2 PF14532.1 KFH48931.1 - 0.016 15.2 0.0 0.079 13.0 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.1 KFH48931.1 - 0.024 14.0 0.1 0.097 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KFH48931.1 - 0.032 14.0 0.1 0.032 14.0 0.1 2.8 2 0 0 2 2 1 0 Part of AAA domain Mg_chelatase PF01078.16 KFH48931.1 - 0.05 12.7 0.2 0.12 11.4 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.12 KFH48931.1 - 0.08 11.7 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 KFH48931.1 - 0.1 12.0 0.0 2.6 7.4 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_3 PF07726.6 KFH48931.1 - 0.12 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.13 KFH48931.1 - 0.18 11.4 0.0 18 4.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein Torsin PF06309.6 KFH48931.1 - 0.5 10.2 0.2 1.2 9.0 0.0 1.6 2 0 0 2 2 1 0 Torsin CDC37_N PF03234.9 KFH48932.1 - 1.5e-57 194.7 2.2 1.5e-57 194.7 1.5 2.2 3 0 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 KFH48932.1 - 3.8e-41 140.4 0.1 3.8e-41 140.4 0.0 2.0 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 KFH48932.1 - 3.9e-22 77.9 1.3 3.9e-22 77.9 0.9 2.7 3 1 0 3 3 3 1 Cdc37 C terminal domain Ribosomal_S8 PF00410.14 KFH48933.1 - 4.3e-25 88.0 0.0 6.1e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Glyco_hydro_3 PF00933.16 KFH48934.1 - 2.4e-86 289.4 0.0 3.2e-86 288.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KFH48934.1 - 1.9e-52 178.0 0.0 1.1e-51 175.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KFH48934.1 - 1.5e-17 63.2 0.1 2.9e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain EHN PF06441.7 KFH48935.1 - 1e-27 96.2 0.0 4.3e-27 94.2 0.0 1.9 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.15 KFH48935.1 - 3.3e-07 30.0 0.4 1.2e-06 28.2 0.1 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KFH48935.1 - 6.3e-07 29.4 1.7 1.6e-06 28.1 0.5 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family ATP-synt_E PF05680.7 KFH48937.1 - 6.2e-23 80.5 0.1 6.7e-23 80.4 0.1 1.1 1 0 0 1 1 1 1 ATP synthase E chain ABC_trans_N PF14510.1 KFH48937.1 - 0.029 14.4 0.5 0.039 14.0 0.3 1.3 1 1 0 1 1 1 0 ABC-transporter extracellular N-terminal Erf4 PF10256.4 KFH48938.1 - 5.9e-30 103.5 0.0 8.3e-30 103.0 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF3602 PF12223.3 KFH48939.1 - 5.3e-11 42.7 13.2 1.4e-05 25.3 1.6 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) GTP1_OBG PF01018.17 KFH48939.1 - 0.38 10.3 6.3 3.7 7.1 0.1 2.8 1 1 2 3 3 3 0 GTP1/OBG Med3 PF11593.3 KFH48939.1 - 0.88 8.7 4.6 0.97 8.5 3.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal YjbE PF11106.3 KFH48939.1 - 2.5 8.1 6.8 4.2 7.4 4.7 1.3 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE Pectate_lyase_3 PF12708.2 KFH48940.1 - 3.9e-84 282.2 20.5 1.2e-69 234.8 5.4 3.0 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KFH48940.1 - 9.6e-05 21.7 5.8 0.12 11.8 0.4 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Glyco_hyd_65N_2 PF14498.1 KFH48941.1 - 6.5e-41 140.5 0.0 1.1e-40 139.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.10 KFH48941.1 - 0.00088 18.0 0.0 0.0015 17.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain DUF3635 PF12330.3 KFH48942.1 - 3.7e-05 23.7 0.1 0.00054 19.9 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3635) Rdx PF10262.4 KFH48943.1 - 1.2e-28 98.9 0.0 1.5e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Rdx family SMC_N PF02463.14 KFH48944.1 - 1.3e-53 181.5 44.3 1.1e-32 113.0 9.6 2.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KFH48944.1 - 5.7e-32 110.1 0.0 6.3e-31 106.8 0.0 2.8 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KFH48944.1 - 1e-16 61.7 1.9 2.8e-08 34.0 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KFH48944.1 - 2.6e-14 54.0 20.6 2.6e-14 54.0 14.3 7.4 2 2 3 5 5 5 1 AAA domain AAA_29 PF13555.1 KFH48944.1 - 0.00074 18.9 0.0 0.0018 17.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Peptidase_C71 PF12386.3 KFH48944.1 - 0.21 10.9 1.9 0.63 9.4 0.0 2.4 2 0 0 2 2 2 0 Pseudomurein endo-isopeptidase Pei ABC_tran PF00005.22 KFH48944.1 - 0.79 10.0 0.0 0.79 10.0 0.0 6.2 3 2 0 3 3 3 0 ABC transporter Med10 PF09748.4 KFH48945.1 - 1.2e-41 141.4 0.0 1.6e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Flagellin_N PF00669.15 KFH48945.1 - 0.087 12.6 0.4 0.16 11.7 0.3 1.4 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region TMEM154 PF15102.1 KFH48946.1 - 0.058 13.0 0.0 0.089 12.5 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family DUF3609 PF12259.3 KFH48946.1 - 0.062 11.9 0.0 0.079 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) MSC PF09402.5 KFH48946.1 - 0.089 11.4 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain RCR PF12273.3 KFH48946.1 - 8.6 6.9 6.8 13 6.2 3.9 1.9 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Xpo1 PF08389.7 KFH48947.1 - 1.9e-35 121.9 0.4 1.9e-35 121.9 0.3 3.3 3 1 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.17 KFH48947.1 - 3.4e-06 26.6 0.5 0.38 10.9 0.0 4.6 4 0 0 4 4 4 2 HEAT repeat DUF3407 PF11887.3 KFH48947.1 - 0.00012 21.5 1.5 0.00024 20.4 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3407) HEAT_EZ PF13513.1 KFH48947.1 - 0.04 14.4 2.4 82 3.8 0.0 4.8 3 1 1 4 4 4 0 HEAT-like repeat RIX1 PF08167.7 KFH48947.1 - 0.066 12.8 0.5 6.3 6.4 0.0 3.3 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis Amidohydro_2 PF04909.9 KFH48948.1 - 4.4e-42 144.5 1.2 6.3e-42 144.0 0.8 1.3 1 1 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 KFH48948.1 - 0.029 13.5 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 TatD related DNase Asparaginase PF00710.15 KFH48948.1 - 0.058 12.2 0.0 0.097 11.5 0.0 1.2 1 0 0 1 1 1 0 Asparaginase Glyco_hydro_1 PF00232.13 KFH48949.1 - 1.1e-151 505.1 0.0 1.3e-151 504.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 DUF3827 PF12877.2 KFH48950.1 - 1.5 6.8 7.9 2.1 6.3 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Tmemb_170 PF10190.4 KFH48951.1 - 0.14 12.2 8.4 0.18 11.8 5.8 1.2 1 0 0 1 1 1 0 Putative transmembrane protein 170 DUF3336 PF11815.3 KFH48952.1 - 1e-52 177.5 9.0 1.5e-52 176.9 6.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KFH48952.1 - 1e-20 74.5 0.2 2.9e-20 73.0 0.0 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase DUF1682 PF07946.9 KFH48953.1 - 6.3e-101 337.4 0.1 7.2e-101 337.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF4398 PF14346.1 KFH48953.1 - 0.33 11.0 15.6 0.67 10.0 10.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) APG6 PF04111.7 KFH48953.1 - 3.8 6.4 11.5 6.3 5.7 8.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Ins_P5_2-kin PF06090.7 KFH48955.1 - 6.2e-39 133.8 0.0 7.8e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase ubiquitin PF00240.18 KFH48956.1 - 6.5e-05 22.2 0.0 0.00013 21.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family RIX1 PF08167.7 KFH48958.1 - 1.3e-42 145.2 0.2 6.9e-42 142.9 0.0 2.1 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis P5CR_dimer PF14748.1 KFH48959.1 - 3.8e-29 100.8 2.8 7.9e-29 99.8 1.9 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KFH48959.1 - 3.8e-12 46.4 0.3 4.4e-10 39.8 0.0 2.5 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent AMP-binding PF00501.23 KFH48960.1 - 5.9e-73 245.6 0.0 7.2e-73 245.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFH48960.1 - 1.9e-16 60.7 0.1 3.6e-16 59.8 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain OKR_DC_1_N PF03709.10 KFH48960.1 - 0.071 13.1 0.0 0.29 11.2 0.0 2.0 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain CAP_N PF01213.14 KFH48960.1 - 0.25 10.5 1.8 0.38 9.9 1.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 KFH48960.1 - 0.74 9.1 3.3 1.3 8.2 2.3 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Carb_anhydrase PF00194.16 KFH48961.1 - 1.8e-21 76.2 0.0 6.9e-21 74.3 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase HET PF06985.6 KFH48962.1 - 2.4e-21 76.3 0.0 6.9e-21 74.8 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF77 PF01910.12 KFH48963.1 - 7.7e-35 118.4 1.1 8.7e-35 118.2 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 Polysacc_deac_1 PF01522.16 KFH48963.1 - 0.0027 17.3 0.0 0.0035 16.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase PCI PF01399.22 KFH48964.1 - 1.8e-08 34.6 0.1 1.8e-08 34.6 0.0 2.9 3 0 0 3 3 3 1 PCI domain CAF-1_p150 PF11600.3 KFH48964.1 - 0.00017 21.0 18.8 0.00017 21.0 13.0 3.5 2 1 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3586 PF12131.3 KFH48965.1 - 0.035 14.1 0.1 0.081 12.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3586) P12 PF12669.2 KFH48965.1 - 0.95 9.7 5.0 1.3 9.2 0.3 2.2 2 0 0 2 2 2 0 Virus attachment protein p12 family Glyco_hydro_16 PF00722.16 KFH48967.1 - 2.6e-13 49.6 0.7 4e-13 49.0 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 HIRAN PF08797.6 KFH48967.1 - 0.12 12.2 0.1 0.53 10.2 0.0 2.1 3 0 0 3 3 3 0 HIRAN domain Ribosomal_L12 PF00542.14 KFH48968.1 - 3.4e-18 65.4 3.3 3.4e-18 65.4 2.3 2.5 3 0 0 3 3 3 1 Ribosomal protein L7/L12 C-terminal domain TrkH PF02386.11 KFH48969.1 - 2.8e-117 391.2 11.5 3.8e-116 387.5 5.9 2.1 2 0 0 2 2 2 2 Cation transport protein His_biosynth PF00977.16 KFH48971.1 - 8.7e-34 116.7 0.0 1.1e-33 116.4 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Aldolase PF01081.14 KFH48971.1 - 0.08 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 KDPG and KHG aldolase Ribul_P_3_epim PF00834.14 KFH48971.1 - 0.13 11.4 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Pkinase PF00069.20 KFH48973.1 - 2.3e-54 184.2 0.0 2.8e-54 184.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFH48973.1 - 1.7e-34 119.0 0.0 2.4e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFH48973.1 - 1.7e-08 33.7 0.0 2.6e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like zf-HC5HC2H_2 PF13832.1 KFH48974.1 - 3.6e-34 117.0 7.6 3.6e-34 117.0 5.3 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KFH48974.1 - 2e-26 91.9 7.0 2e-26 91.9 4.8 3.2 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 KFH48974.1 - 1.8e-21 77.0 1.2 9.9e-21 74.6 0.4 2.7 2 1 0 2 2 2 1 Enhancer of polycomb-like PHD_2 PF13831.1 KFH48974.1 - 9.6e-15 53.6 2.4 9.6e-15 53.6 1.7 2.2 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 KFH48974.1 - 7.1e-08 32.0 28.4 5.2e-07 29.2 8.9 2.7 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.1 KFH48974.1 - 5.1 6.3 15.6 0.028 13.7 2.1 2.5 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Stb3 PF10330.4 KFH48975.1 - 4.7e-37 125.5 0.0 7.7e-37 124.8 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein p450 PF00067.17 KFH48976.1 - 8.8e-54 182.7 0.0 1.2e-53 182.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TPR_11 PF13414.1 KFH48977.1 - 2e-05 24.1 0.6 3.7e-05 23.2 0.4 1.4 1 0 0 1 1 1 1 TPR repeat TPR_14 PF13428.1 KFH48977.1 - 0.00051 20.4 3.8 0.024 15.2 0.5 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFH48977.1 - 0.00074 19.3 0.3 0.0016 18.3 0.2 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFH48977.1 - 0.0028 17.2 0.2 0.13 11.9 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFH48977.1 - 0.0081 16.8 3.7 0.017 15.7 2.0 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFH48977.1 - 0.011 15.5 2.8 0.055 13.3 0.3 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.7 KFH48977.1 - 0.44 11.2 2.0 0.5 11.0 0.4 1.9 2 0 0 2 2 2 0 Sel1 repeat Zip PF02535.17 KFH48978.1 - 1.2e-34 119.8 0.2 4e-34 118.0 0.1 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter MAP2_projctn PF08377.5 KFH48978.1 - 0.061 10.8 2.6 0.085 10.3 1.8 1.1 1 0 0 1 1 1 0 MAP2/Tau projection domain zf-CHY PF05495.7 KFH48979.1 - 1.1e-13 51.0 21.2 1.5e-13 50.6 14.7 1.1 1 0 0 1 1 1 1 CHY zinc finger Zn_Tnp_IS1595 PF12760.2 KFH48979.1 - 0.17 11.7 12.3 3.1 7.6 5.8 2.7 2 1 0 2 2 2 0 Transposase zinc-ribbon domain C1_4 PF07975.7 KFH48979.1 - 0.72 9.9 16.2 4.3 7.4 5.0 2.6 1 1 2 3 3 3 0 TFIIH C1-like domain DUF3797 PF12677.2 KFH48979.1 - 0.72 9.5 0.0 0.72 9.5 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3797) Evr1_Alr PF04777.8 KFH48979.1 - 2.7 7.9 13.3 21 5.0 6.9 2.7 1 1 1 2 2 2 0 Erv1 / Alr family HypA PF01155.14 KFH48979.1 - 2.9 7.6 11.9 0.12 12.1 3.0 2.0 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-RING_3 PF14369.1 KFH48979.1 - 4.3 7.4 11.9 1.3 9.0 4.7 2.5 1 1 1 2 2 2 0 zinc-finger DUF1900 PF08954.6 KFH48980.1 - 1.4e-49 167.1 0.0 2.1e-48 163.3 0.0 2.5 2 1 1 3 3 3 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 KFH48980.1 - 3.6e-34 116.2 0.0 8e-34 115.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 KFH48980.1 - 1e-20 72.7 1.6 2.4e-07 30.3 0.1 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 KFH48980.1 - 0.023 12.8 0.2 0.84 7.6 0.2 2.2 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Ribosomal_L10 PF00466.15 KFH48981.1 - 4.5e-20 71.4 0.0 7e-20 70.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 LMBR1 PF04791.11 KFH48984.1 - 1.8e-29 102.6 9.2 2.7e-29 102.0 6.4 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF2207 PF09972.4 KFH48984.1 - 0.45 9.0 4.9 0.31 9.5 0.1 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) IncA PF04156.9 KFH48984.1 - 3.1 7.3 3.6 2.3 7.7 0.1 2.3 2 0 0 2 2 2 0 IncA protein BUD22 PF09073.5 KFH48985.1 - 0.0012 18.0 15.2 0.0012 18.0 10.5 1.4 2 0 0 2 2 2 1 BUD22 eIF-3c_N PF05470.7 KFH48985.1 - 0.22 9.5 7.1 0.25 9.3 4.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus RP-C_C PF11800.3 KFH48985.1 - 3.5 7.2 9.0 8.4 6.0 6.3 1.9 1 1 0 1 1 1 0 Replication protein C C-terminal region RNA_pol_Rpb6 PF01192.17 KFH48986.1 - 3.5e-24 84.2 0.3 6.8e-24 83.3 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb6 Esterase PF00756.15 KFH48987.1 - 1.3e-47 162.3 0.0 1.6e-47 162.0 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 KFH48987.1 - 8.4e-08 32.0 0.0 1.1e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 KFH48987.1 - 8.7e-06 25.1 0.0 3.2e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KFH48987.1 - 0.0001 21.6 0.1 0.00015 21.0 0.1 1.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KFH48987.1 - 0.002 18.0 0.1 0.0026 17.6 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KFH48987.1 - 0.071 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme MRP-L46 PF11788.3 KFH48989.1 - 1.1e-20 74.3 0.0 1.7e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 KFH48989.1 - 1.2e-05 25.0 0.0 2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain FAD-oxidase_C PF02913.14 KFH48990.1 - 2.8e-51 174.2 0.2 5.3e-51 173.3 0.0 1.6 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KFH48990.1 - 2.3e-36 124.3 0.2 4e-36 123.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain DUF2235 PF09994.4 KFH48991.1 - 1.8e-64 217.8 0.0 3.8e-64 216.7 0.0 1.5 2 0 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 KFH48991.1 - 0.06 13.0 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family MBOAT PF03062.14 KFH48992.1 - 1.4e-20 73.6 18.0 1.4e-20 73.6 12.5 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 KFH48992.1 - 0.00073 19.5 2.7 0.0027 17.7 1.9 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Phage_Mu_F PF04233.9 KFH48992.1 - 0.056 13.9 0.6 0.1 13.1 0.4 1.3 1 0 0 1 1 1 0 Phage Mu protein F like protein Dicty_REP PF05086.7 KFH48992.1 - 0.58 7.8 8.1 0.79 7.3 5.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Zn_clus PF00172.13 KFH48993.1 - 0.019 14.8 8.6 0.033 14.0 6.0 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFH48993.1 - 0.02 13.8 0.1 0.055 12.3 0.0 1.7 1 1 1 2 2 2 0 Fungal specific transcription factor domain Lipase_GDSL PF00657.17 KFH48994.1 - 2.8e-05 24.0 0.0 0.026 14.3 0.0 2.1 1 1 1 2 2 2 2 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KFH48994.1 - 3.6e-05 23.9 0.0 0.0021 18.2 0.0 2.2 1 1 1 2 2 2 2 GDSL-like Lipase/Acylhydrolase family UBA_4 PF14555.1 KFH48995.1 - 0.0014 18.1 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 UBA-like domain LysM PF01476.15 KFH48995.1 - 0.0039 17.0 0.0 0.0061 16.4 0.0 1.3 1 0 0 1 1 1 1 LysM domain Zn_clus PF00172.13 KFH48996.1 - 0.26 11.2 14.4 0.13 12.1 2.6 2.4 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain APH PF01636.18 KFH48997.1 - 1.4e-15 57.7 0.2 2.1e-15 57.0 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 KFH48997.1 - 2.3e-06 26.9 0.0 0.0067 15.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Choline_kinase PF01633.15 KFH48997.1 - 6.4e-05 22.6 0.0 0.00024 20.7 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.12 KFH48997.1 - 0.0036 16.3 0.0 0.0062 15.6 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KFH48997.1 - 0.0099 15.2 0.2 0.14 11.5 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Endonuclease_NS PF01223.18 KFH48998.1 - 2.7e-60 203.5 0.0 3.4e-60 203.2 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease DUF3948 PF13134.1 KFH48998.1 - 0.59 9.6 3.4 12 5.4 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3948) ketoacyl-synt PF00109.21 KFH48999.1 - 2.6e-56 190.9 1.7 2.6e-56 190.9 1.2 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KFH48999.1 - 2.2e-33 114.6 0.8 4.1e-33 113.7 0.6 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 KFH48999.1 - 0.049 12.6 0.2 0.15 11.0 0.0 1.7 2 0 0 2 2 2 0 Thiolase, N-terminal domain SNF2_N PF00176.18 KFH49000.1 - 1.2e-46 158.9 0.4 5.2e-46 156.7 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFH49000.1 - 5.9e-15 54.8 0.1 2.2e-14 53.0 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFH49000.1 - 0.00073 19.4 0.0 0.002 17.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KFH49000.1 - 0.00097 18.6 0.0 0.0041 16.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase U1snRNP70_N PF12220.3 KFH49001.1 - 9e-30 102.8 3.3 1.7e-29 101.9 2.3 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 KFH49001.1 - 1.3e-12 47.1 0.1 7.7e-12 44.6 0.1 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFH49001.1 - 6.4e-09 35.6 0.0 1.5e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFH49001.1 - 8e-05 22.4 0.2 0.00019 21.2 0.1 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cylicin_N PF15241.1 KFH49001.1 - 0.043 13.6 0.2 0.085 12.7 0.1 1.4 1 0 0 1 1 1 0 Cylicin N-terminus zf-Tim10_DDP PF02953.10 KFH49002.1 - 8.4e-18 63.4 0.4 8.4e-18 63.4 0.3 1.9 2 0 0 2 2 2 1 Tim10/DDP family zinc finger PALP PF00291.20 KFH49003.1 - 3e-58 197.4 0.1 4.2e-58 197.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zf-RING_2 PF13639.1 KFH49003.1 - 4e-07 29.7 6.9 4e-07 29.7 4.8 4.3 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.20 KFH49003.1 - 1.7e-06 27.5 5.7 1.7e-06 27.5 3.9 4.9 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KFH49003.1 - 5.4e-06 26.0 0.3 5.4e-06 26.0 0.2 3.6 4 0 0 4 4 4 1 zf-RING of BARD1-type protein SH3_9 PF14604.1 KFH49003.1 - 6.8e-06 25.5 0.1 6.8e-06 25.5 0.1 2.2 2 0 0 2 2 2 1 Variant SH3 domain zf-C3HC4_2 PF13923.1 KFH49003.1 - 2e-05 24.5 6.0 2e-05 24.5 4.1 5.4 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFH49003.1 - 0.00015 21.5 4.9 0.00015 21.5 3.4 5.2 5 2 1 6 6 6 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KFH49003.1 - 0.0004 20.0 4.6 0.0004 20.0 3.2 5.8 6 0 0 6 6 6 1 zinc-RING finger domain SH3_1 PF00018.23 KFH49003.1 - 0.0011 18.2 0.0 0.0024 17.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain zf-RING_UBOX PF13445.1 KFH49003.1 - 0.0042 16.7 2.6 0.013 15.1 1.8 2.0 1 0 0 1 1 1 1 RING-type zinc-finger 2OG-FeII_Oxy_2 PF13532.1 KFH49004.1 - 0.00031 20.6 0.2 0.061 13.1 0.1 2.9 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KFH49004.1 - 0.032 14.5 0.1 0.29 11.4 0.1 2.5 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Zn_clus PF00172.13 KFH49005.1 - 1e-08 34.9 6.8 1.7e-08 34.1 4.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFH49005.1 - 0.0031 16.1 1.8 0.0057 15.3 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Afi1 PF07792.7 KFH49006.1 - 3.6e-62 208.6 0.0 6.2e-62 207.8 0.0 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 KFH49006.1 - 2.3e-36 123.9 0.0 4.6e-36 122.9 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 KFH49006.1 - 2.1e-07 29.7 0.1 0.012 14.1 0.0 3.6 3 1 1 4 4 4 2 Transport protein Avl9 DUF2347 PF09804.4 KFH49006.1 - 0.058 12.6 0.0 0.44 9.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) NACHT PF05729.7 KFH49007.1 - 5e-09 36.0 0.0 1.2e-08 34.7 0.0 1.7 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KFH49007.1 - 2.6e-07 30.8 0.2 1.6e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KFH49007.1 - 0.0034 17.5 0.1 0.013 15.5 0.0 2.0 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.17 KFH49007.1 - 0.0054 15.6 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_25 PF13481.1 KFH49007.1 - 0.0074 15.7 0.0 0.034 13.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KFH49007.1 - 0.025 14.4 0.0 0.1 12.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain NPV_P10 PF05531.7 KFH49007.1 - 0.058 13.6 3.1 1.2 9.4 0.3 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein AAA_10 PF12846.2 KFH49007.1 - 0.058 12.8 0.2 1.4 8.2 0.0 2.8 2 2 2 4 4 4 0 AAA-like domain ABC_tran PF00005.22 KFH49007.1 - 0.062 13.5 0.1 0.63 10.3 0.0 2.4 2 1 0 2 2 2 0 ABC transporter MCPsignal PF00015.16 KFH49007.1 - 0.074 12.5 1.0 4.6 6.7 0.5 2.4 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain USP7_C2 PF14533.1 KFH49007.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal Ribosomal_L37ae PF01780.14 KFH49008.1 - 2e-39 133.3 10.5 2.2e-39 133.2 7.3 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family A2L_zn_ribbon PF08792.5 KFH49008.1 - 0.007 15.7 3.6 0.071 12.5 0.1 2.1 2 0 0 2 2 2 1 A2L zinc ribbon domain Elf1 PF05129.8 KFH49008.1 - 0.016 14.9 0.2 0.023 14.4 0.2 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.2 KFH49008.1 - 0.038 13.7 3.0 0.062 13.1 2.1 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Sgf11 PF08209.6 KFH49008.1 - 0.05 12.9 1.4 0.16 11.2 0.1 2.1 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) OrfB_Zn_ribbon PF07282.6 KFH49008.1 - 0.11 12.1 0.9 0.15 11.7 0.6 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-H2C2_2 PF13465.1 KFH49008.1 - 0.12 12.6 1.1 0.26 11.6 0.1 2.0 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.21 KFH49008.1 - 0.28 11.5 2.1 1.4 9.4 0.1 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type CarbpepA_inh PF02977.10 KFH49008.1 - 0.57 9.8 3.4 4 7.1 2.4 2.1 1 1 0 1 1 1 0 Carboxypeptidase A inhibitor zf-BED PF02892.10 KFH49008.1 - 0.57 9.9 4.8 1.9 8.2 0.3 2.3 1 1 1 2 2 2 0 BED zinc finger Pyr_redox_3 PF13738.1 KFH49010.1 - 8.6e-21 74.9 0.0 1.4e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFH49010.1 - 8.1e-17 60.6 0.0 5.5e-13 47.9 0.0 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KFH49010.1 - 1.8e-12 47.0 0.0 4.5e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KFH49010.1 - 4.1e-07 29.2 0.0 0.00022 20.2 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KFH49010.1 - 9.3e-06 25.4 0.0 3e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 KFH49010.1 - 1e-05 24.6 0.0 0.00037 19.5 0.0 2.7 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFH49010.1 - 0.0042 17.0 0.0 0.12 12.2 0.0 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFH49010.1 - 0.018 14.1 0.0 0.073 12.1 0.0 1.8 2 0 0 2 2 2 0 Thi4 family GSH_synth_ATP PF03917.12 KFH49012.1 - 1.6e-110 369.2 0.0 1.9e-110 368.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 KFH49012.1 - 1.6e-31 108.4 0.0 2.8e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Aldedh PF00171.17 KFH49013.1 - 1.1e-170 567.9 0.1 1.3e-170 567.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pox_Ag35 PF03286.9 KFH49014.1 - 0.081 12.4 3.7 0.12 11.8 2.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4140 PF13600.1 KFH49014.1 - 0.12 12.8 3.2 0.25 11.7 2.2 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) PspB PF06667.7 KFH49014.1 - 0.14 12.0 5.2 0.24 11.3 3.6 1.4 1 0 0 1 1 1 0 Phage shock protein B Herpes_UL25 PF01499.11 KFH49014.1 - 0.32 9.2 2.3 0.48 8.6 1.6 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF4463 PF14703.1 KFH49014.1 - 0.34 11.4 6.0 0.068 13.6 0.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4463) bZIP_1 PF00170.16 KFH49014.1 - 0.8 9.6 20.3 2.5 8.1 14.0 1.8 1 1 1 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.10 KFH49014.1 - 1.3 8.8 21.6 0.63 9.8 13.5 1.5 1 1 0 1 1 1 0 Basic region leucine zipper IncA PF04156.9 KFH49014.1 - 4.7 6.7 8.8 6.9 6.2 6.1 1.1 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 KFH49014.1 - 4.8 6.1 9.4 6.7 5.6 6.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2183 PF09949.4 KFH49015.1 - 8.6e-32 109.0 0.0 2.6e-31 107.4 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.8 KFH49015.1 - 0.001 18.6 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) IncA PF04156.9 KFH49015.1 - 8 6.0 0.0 8 6.0 0.0 3.1 3 0 0 3 3 3 0 IncA protein STE PF02200.11 KFH49016.1 - 1.8e-51 172.8 0.1 3.4e-51 171.9 0.1 1.4 1 0 0 1 1 1 1 STE like transcription factor zf-H2C2_2 PF13465.1 KFH49016.1 - 2.7e-08 33.7 2.5 2.7e-08 33.7 1.7 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 KFH49016.1 - 5.1e-07 29.6 12.6 0.00059 20.0 2.0 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFH49016.1 - 5.9e-07 29.3 7.1 0.00095 19.3 1.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-RING_3 PF14369.1 KFH49016.1 - 0.039 13.9 0.2 0.095 12.7 0.1 1.6 1 0 0 1 1 1 0 zinc-finger HTH_Tnp_Tc5 PF03221.11 KFH49017.1 - 1.5e-11 43.9 0.0 4.5e-10 39.2 0.0 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 KFH49017.1 - 5.5e-10 38.5 0.1 1e-09 37.6 0.1 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.1 KFH49017.1 - 0.0027 17.3 0.0 0.012 15.2 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.1 KFH49017.1 - 0.0048 16.4 0.0 0.014 14.9 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.17 KFH49017.1 - 0.031 13.9 0.0 0.11 12.2 0.0 2.0 1 0 0 1 1 1 0 MarR family HTH_Tnp_4 PF13613.1 KFH49017.1 - 0.064 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease MarR_2 PF12802.2 KFH49017.1 - 0.1 12.3 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 MarR family Sigma70_r4 PF04545.11 KFH49017.1 - 0.19 11.0 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 Myb_DNA-binding PF00249.26 KFH49018.1 - 0.15 12.1 0.0 0.57 10.2 0.0 2.0 1 0 0 1 1 1 0 Myb-like DNA-binding domain AMP-binding PF00501.23 KFH49019.1 - 4.2e-60 203.2 3.3 7.8e-23 80.5 0.0 5.0 4 1 0 4 4 4 4 AMP-binding enzyme DMAP_binding PF06464.6 KFH49019.1 - 2.5e-11 44.1 0.1 7.7e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 DMAP1-binding Domain GvpG PF05120.7 KFH49019.1 - 5e-05 23.0 0.2 0.00012 21.7 0.1 1.6 1 0 0 1 1 1 1 Gas vesicle protein G Ecl1 PF12855.2 KFH49020.1 - 2e-12 46.2 1.4 3.5e-12 45.3 1.0 1.3 1 0 0 1 1 1 1 Life-span regulatory factor DUF581 PF04570.9 KFH49020.1 - 0.027 13.7 3.1 0.054 12.7 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF581) C1_1 PF00130.17 KFH49020.1 - 0.06 13.0 0.6 0.1 12.3 0.4 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF329 PF03884.9 KFH49020.1 - 0.061 12.8 2.1 0.14 11.7 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF329) Ribosomal_L19 PF01245.15 KFH49021.1 - 1.4e-12 47.4 0.0 2.4e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 Glyco_hydro_61 PF03443.9 KFH49022.1 - 2.9e-58 197.2 0.8 3.6e-58 196.9 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 BP28CT PF08146.7 KFH49023.1 - 3.2e-40 137.3 0.1 6.7e-39 133.0 0.0 3.1 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 KFH49023.1 - 2e-21 76.1 0.2 2e-21 76.1 0.1 4.9 6 0 0 6 6 6 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.1 KFH49023.1 - 5.3e-08 33.0 13.5 0.21 11.8 0.3 7.4 7 1 0 7 7 7 3 HEAT repeats HEAT PF02985.17 KFH49023.1 - 3.3e-07 29.8 10.1 0.012 15.6 0.0 7.1 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 KFH49023.1 - 0.33 11.4 18.7 1 9.9 0.1 8.0 8 1 1 9 9 9 0 HEAT-like repeat WD40 PF00400.27 KFH49024.1 - 1.3e-47 157.9 17.4 1.9e-09 37.0 0.1 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 KFH49024.1 - 7.8e-12 44.7 0.7 1.6e-11 43.6 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFH49024.1 - 2.2e-08 33.5 0.1 4.3e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 KFH49024.1 - 5.2e-06 24.8 2.0 0.15 10.1 0.0 3.8 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFH49024.1 - 0.002 16.9 0.5 1.2 7.8 0.1 3.1 2 2 1 3 3 3 2 Nup133 N terminal like PQQ_2 PF13360.1 KFH49024.1 - 0.0043 16.5 0.0 0.067 12.6 0.0 2.4 1 1 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.11 KFH49024.1 - 0.018 13.3 0.1 0.049 11.9 0.1 1.7 1 0 0 1 1 1 0 Cytochrome D1 heme domain FlaG PF03646.10 KFH49024.1 - 0.03 14.4 0.0 5.4 7.2 0.0 2.9 3 0 0 3 3 3 0 FlaG protein iPGM_N PF06415.8 KFH49025.1 - 7.8e-70 234.6 0.0 1.2e-69 234.0 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.13 KFH49025.1 - 9.8e-69 231.5 0.1 1.1e-68 231.3 0.1 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.17 KFH49025.1 - 1.2e-08 34.7 0.0 1.8e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KFH49025.1 - 6.3e-06 25.5 0.0 0.00014 21.2 0.0 2.1 1 1 0 1 1 1 1 Sulfatase PglZ PF08665.7 KFH49025.1 - 0.033 13.8 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 PglZ domain ATP-synt_DE_N PF02823.11 KFH49026.1 - 1.5e-19 69.5 0.1 2.2e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain HELP PF03451.9 KFH49026.1 - 0.051 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 HELP motif STE3 PF02076.10 KFH49027.1 - 6.6e-41 140.2 13.2 8.2e-41 139.9 9.1 1.1 1 0 0 1 1 1 1 Pheromone A receptor zf-Mss51 PF13824.1 KFH49028.1 - 1.5e-28 98.3 5.9 2.9e-28 97.4 4.1 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 KFH49028.1 - 0.0035 17.1 0.3 0.0035 17.1 0.2 1.8 2 0 0 2 2 2 1 MYND finger Iso_dh PF00180.15 KFH49029.1 - 1.8e-129 431.6 0.0 2.1e-129 431.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Urb2 PF10441.4 KFH49030.1 - 4e-52 177.0 0.0 1.5e-51 175.1 0.0 2.1 2 0 0 2 2 2 1 Urb2/Npa2 family Abhydrolase_6 PF12697.2 KFH49032.1 - 5.2e-34 118.0 0.2 7.9e-34 117.5 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFH49032.1 - 1.6e-16 60.5 0.0 7.4e-15 55.1 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFH49032.1 - 1e-12 48.0 0.0 2.9e-12 46.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KFH49032.1 - 2.9e-05 23.8 0.0 5.2e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 KFH49032.1 - 0.0039 16.4 0.1 0.058 12.5 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Sec63 PF02889.11 KFH49034.1 - 1e-44 153.0 0.0 1.8e-43 148.9 0.0 2.5 2 1 0 2 2 2 1 Sec63 Brl domain DnaJ PF00226.26 KFH49034.1 - 6.2e-18 64.2 1.0 1.4e-17 63.1 0.7 1.7 1 0 0 1 1 1 1 DnaJ domain EB1 PF03271.12 KFH49035.1 - 1.3e-17 63.5 1.7 2.6e-17 62.5 1.2 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 KFH49035.1 - 4.2e-08 33.2 1.3 6.5e-08 32.5 0.9 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain HMG_box PF00505.14 KFH49036.1 - 1.3e-05 25.3 0.3 4.8e-05 23.5 0.2 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFH49036.1 - 0.0053 17.1 0.5 0.0053 17.1 0.4 2.1 2 1 0 2 2 2 1 HMG-box domain SAD_SRA PF02182.12 KFH49037.1 - 0.00016 20.9 0.0 0.00027 20.2 0.0 1.3 1 0 0 1 1 1 1 SAD/SRA domain Acyltransferase PF01553.16 KFH49039.1 - 1.3e-32 111.9 0.0 2e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Ribonuc_L-PSP PF01042.16 KFH49039.1 - 0.018 14.8 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 Endoribonuclease L-PSP Yip1 PF04893.12 KFH49039.1 - 0.18 11.3 8.6 0.32 10.4 6.0 1.5 1 0 0 1 1 1 0 Yip1 domain Topoisom_bac PF01131.15 KFH49040.1 - 1.1e-92 310.9 0.0 8.5e-88 294.8 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.17 KFH49040.1 - 5.5e-18 64.7 0.0 1.2e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 Toprim domain bZIP_1 PF00170.16 KFH49041.1 - 5.6e-06 26.2 6.7 5.6e-06 26.2 4.6 1.7 2 0 0 2 2 2 1 bZIP transcription factor GvpL_GvpF PF06386.6 KFH49041.1 - 0.049 13.2 2.8 0.084 12.4 2.0 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF4407 PF14362.1 KFH49041.1 - 0.22 10.4 4.2 0.46 9.3 2.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) bZIP_2 PF07716.10 KFH49041.1 - 0.47 10.3 9.6 0.19 11.6 4.0 2.2 2 0 0 2 2 2 0 Basic region leucine zipper DUF4203 PF13886.1 KFH49042.1 - 8.7e-34 116.8 23.1 1.1e-33 116.4 16.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Rhabdo_ncap PF00945.13 KFH49042.1 - 0.13 10.8 0.1 0.23 10.0 0.1 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein OAD_gamma PF04277.8 KFH49042.1 - 1.2 9.5 7.0 4.5 7.7 0.1 3.6 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DUF4451 PF14616.1 KFH49043.1 - 2.2e-35 121.1 0.4 3.6e-35 120.4 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) L51_S25_CI-B8 PF05047.11 KFH49044.1 - 5.7e-15 54.7 0.0 1.1e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF187 PF02638.10 KFH49044.1 - 0.11 11.2 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase like GH101 WD40 PF00400.27 KFH49046.1 - 5.1e-20 70.5 15.9 3.8e-05 23.4 0.2 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat BBS2_N PF14781.1 KFH49046.1 - 0.12 11.9 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal Cwf_Cwc_15 PF04889.7 KFH49046.1 - 8.3 6.0 10.0 0.18 11.4 1.9 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Rer1 PF03248.8 KFH49048.1 - 1.1e-80 269.3 9.7 1.3e-80 269.1 6.7 1.0 1 0 0 1 1 1 1 Rer1 family DUF4131 PF13567.1 KFH49048.1 - 0.51 9.7 9.5 0.27 10.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) CIAPIN1 PF05093.8 KFH49049.1 - 1.7e-33 114.6 3.4 2.6e-33 114.0 2.4 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis VirE PF05272.6 KFH49049.1 - 0.01 15.3 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E Hom_end PF05204.9 KFH49049.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Homing endonuclease Arf PF00025.16 KFH49050.1 - 1.3e-66 223.1 0.0 1.5e-66 222.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KFH49050.1 - 3.4e-10 39.1 0.1 1.4e-06 27.2 0.0 2.2 1 1 0 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 KFH49050.1 - 5.1e-08 32.3 0.0 6.7e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KFH49050.1 - 5.2e-08 33.3 0.0 7.2e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 KFH49050.1 - 1.4e-07 31.0 0.0 1.9e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 KFH49050.1 - 3.4e-07 30.2 0.0 4.5e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFH49050.1 - 3.9e-05 22.8 0.0 4.3e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFH49050.1 - 0.00047 19.6 0.1 0.023 14.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 KFH49050.1 - 0.11 12.0 0.0 0.24 10.8 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF4149 PF13664.1 KFH49051.1 - 6.6e-25 87.1 5.1 7.3e-25 86.9 2.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Fungal_trans PF04082.13 KFH49052.1 - 2.4e-23 82.3 0.1 4.1e-23 81.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFH49052.1 - 1.2e-05 25.1 15.4 2.3e-05 24.2 10.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF883 PF05957.8 KFH49052.1 - 0.0063 16.8 1.7 0.012 15.9 0.0 2.4 3 0 0 3 3 3 1 Bacterial protein of unknown function (DUF883) Duffy_binding PF05424.6 KFH49052.1 - 0.15 11.8 1.2 1.7 8.4 0.1 2.3 2 0 0 2 2 2 0 Duffy binding domain DUF1469 PF07332.6 KFH49053.1 - 0.36 10.5 1.6 0.83 9.3 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Asp-B-Hydro_N PF05279.6 KFH49053.1 - 1.3 8.7 30.9 2 8.2 21.4 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Borrelia_P83 PF05262.6 KFH49053.1 - 5.7 5.0 29.8 7.6 4.6 20.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein V_ATPase_I PF01496.14 KFH49053.1 - 5.8 4.6 18.8 8.4 4.1 13.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PH_10 PF15411.1 KFH49054.1 - 4.4e-25 88.1 0.2 7.2e-25 87.4 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 KFH49054.1 - 1e-10 41.5 0.0 2.7e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KFH49054.1 - 3.3e-08 33.4 0.0 5.8e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.1 KFH49054.1 - 6e-08 32.3 6.2 1.1e-07 31.5 4.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KFH49054.1 - 0.00087 18.9 5.2 0.0014 18.2 3.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KFH49054.1 - 0.0029 17.6 1.4 0.0057 16.7 0.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KFH49054.1 - 0.033 14.2 5.0 0.058 13.4 3.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFH49054.1 - 0.075 12.7 5.2 0.14 11.8 3.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1147 PF06615.6 KFH49054.1 - 0.18 11.6 0.4 0.4 10.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) zf-RING-like PF08746.6 KFH49054.1 - 1.1 9.3 4.5 1.9 8.5 3.1 1.4 1 0 0 1 1 1 0 RING-like domain PDEase_II PF02112.10 KFH49057.1 - 1e-54 185.7 0.0 3.5e-22 78.7 0.0 3.2 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 KFH49057.1 - 0.0029 17.1 0.0 0.0097 15.4 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KFH49057.1 - 0.019 14.6 0.4 0.13 11.9 0.3 2.3 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily PAT1 PF09770.4 KFH49058.1 - 1.7 6.7 18.2 2.1 6.4 12.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BCNT PF07572.7 KFH49059.1 - 3.2e-23 81.4 1.7 7.3e-23 80.3 1.2 1.7 1 0 0 1 1 1 1 Bucentaur or craniofacial development Lin-8 PF03353.10 KFH49059.1 - 7.4 5.7 7.5 0.31 10.2 1.2 1.7 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist SYF2 PF08231.7 KFH49061.1 - 3.1e-52 176.7 14.3 3.1e-52 176.7 9.9 1.9 2 0 0 2 2 2 1 SYF2 splicing factor OmpH PF03938.9 KFH49061.1 - 0.54 10.1 19.6 0.51 10.2 5.5 2.8 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Glyco_hydro_2 PF00703.16 KFH49063.1 - 1.6e-09 38.1 0.0 5.9e-09 36.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 KFH49063.1 - 2.9e-07 30.2 0.2 5.6e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KFH49063.1 - 0.00026 19.9 0.0 0.00044 19.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF3439 PF11921.3 KFH49063.1 - 0.023 14.4 0.3 0.05 13.3 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF482 PF04339.7 KFH49063.1 - 0.042 12.7 0.0 0.07 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF482 Arf PF00025.16 KFH49064.1 - 7.8e-59 197.8 0.4 8.9e-59 197.6 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KFH49064.1 - 1.8e-09 36.8 0.7 0.00062 18.5 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 KFH49064.1 - 4.1e-09 36.0 0.0 4.8e-09 35.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KFH49064.1 - 6.8e-08 31.9 0.0 8.4e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFH49064.1 - 9e-08 32.0 0.0 1.3e-07 31.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFH49064.1 - 1.6e-07 31.8 0.0 2.1e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 KFH49064.1 - 6.9e-07 28.6 0.0 9.1e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 KFH49064.1 - 0.012 15.0 0.0 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 KFH49064.1 - 0.015 16.1 0.2 0.023 15.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 KFH49064.1 - 0.016 15.0 0.0 0.41 10.4 0.0 2.2 2 0 0 2 2 2 0 Dynamin family PduV-EutP PF10662.4 KFH49064.1 - 0.025 14.0 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation 6PF2K PF01591.13 KFH49064.1 - 0.14 11.1 0.1 0.34 9.9 0.0 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Whi5 PF08528.6 KFH49065.1 - 9.6e-08 31.4 0.0 1.7e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Whi5 like Cwf_Cwc_15 PF04889.7 KFH49065.1 - 0.013 15.2 5.8 0.021 14.5 4.0 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PBP_sp32 PF07222.7 KFH49065.1 - 0.58 9.2 3.5 1.2 8.2 2.4 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CDC45 PF02724.9 KFH49065.1 - 5.8 4.8 10.0 8.6 4.2 6.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.9 KFH49065.1 - 9.4 5.6 8.4 2.2 7.7 3.6 1.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Ribosomal_L7Ae PF01248.21 KFH49066.1 - 2.2e-29 100.8 1.1 2.7e-29 100.5 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PucR PF07905.6 KFH49066.1 - 0.074 12.6 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family APH PF01636.18 KFH49067.1 - 1.5e-09 37.9 0.2 2.7e-09 37.1 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFH49067.1 - 0.025 14.1 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase IcmF-related PF06761.7 KFH49067.1 - 0.15 11.2 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Intracellular multiplication and human macrophage-killing Actin PF00022.14 KFH49068.1 - 9.8e-31 106.5 0.0 6.4e-19 67.6 0.0 3.0 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 KFH49068.1 - 0.0058 15.2 0.0 0.033 12.7 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein NRDE-2 PF08424.5 KFH49069.1 - 2.8e-82 276.2 3.0 3e-81 272.8 1.3 2.3 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 KFH49069.1 - 0.00015 22.1 0.0 12 6.8 0.1 5.8 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFH49069.1 - 0.0019 18.7 0.0 8.6 7.1 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFH49069.1 - 0.01 15.9 0.1 0.076 13.2 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFH49069.1 - 0.038 14.3 0.0 0.15 12.4 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Trp_DMAT PF11991.3 KFH49070.1 - 3.6e-86 289.6 0.0 4.4e-86 289.3 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase OPT PF03169.10 KFH49072.1 - 5.8e-189 629.5 44.9 6.6e-189 629.3 31.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CcmD PF04995.9 KFH49072.1 - 0.024 14.3 0.1 0.15 11.8 0.1 2.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF2207 PF09972.4 KFH49072.1 - 0.75 8.3 7.6 0.6 8.6 1.5 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Mtc PF03820.12 KFH49073.1 - 1.1e-95 319.8 0.1 8.8e-95 316.8 0.1 2.0 1 1 0 1 1 1 1 Tricarboxylate carrier Glyco_transf_90 PF05686.7 KFH49074.1 - 9.9e-15 54.1 2.5 4.7e-11 42.0 0.5 3.3 2 1 0 2 2 2 2 Glycosyl transferase family 90 TIM PF00121.13 KFH49076.1 - 1.1e-88 296.4 0.6 1.3e-88 296.2 0.4 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Toprim PF01751.17 KFH49076.1 - 0.08 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Toprim domain STT3 PF02516.9 KFH49077.1 - 7.4e-130 434.1 38.6 2.8e-125 419.0 25.0 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Dpy19 PF10034.4 KFH49077.1 - 0.0085 14.3 0.0 0.017 13.2 0.0 1.5 1 0 0 1 1 1 1 Q-cell neuroblast polarisation Abhydrolase_5 PF12695.2 KFH49078.1 - 5.4e-07 29.4 1.3 0.00018 21.2 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family PGAP1 PF07819.8 KFH49078.1 - 0.0013 18.3 0.1 0.0025 17.4 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 KFH49078.1 - 0.0054 16.0 0.0 0.0083 15.4 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_2 PF02230.11 KFH49078.1 - 0.064 12.6 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Thioesterase PF00975.15 KFH49078.1 - 0.064 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_6 PF12697.2 KFH49078.1 - 0.11 12.3 5.3 0.28 11.0 3.6 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2404 PF10296.4 KFH49080.1 - 8.8e-05 22.5 0.0 0.00048 20.1 0.0 2.0 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) zf-C2H2 PF00096.21 KFH49081.1 - 0.014 15.6 3.6 0.037 14.3 2.5 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFH49081.1 - 0.022 15.0 2.5 0.056 13.7 1.7 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-BED PF02892.10 KFH49081.1 - 0.04 13.6 2.7 0.086 12.6 1.8 1.5 1 0 0 1 1 1 0 BED zinc finger zf-H2C2_2 PF13465.1 KFH49081.1 - 0.38 11.1 2.6 10 6.6 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger double domain DUF4484 PF14831.1 KFH49082.1 - 1.1e-12 48.4 0.6 1.1e-12 48.4 0.4 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4484) PHF5 PF03660.9 KFH49084.1 - 4.6e-52 174.5 9.9 5.2e-52 174.4 6.9 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 KFH49084.1 - 0.8 9.5 15.3 0.18 11.6 5.3 2.8 1 1 1 2 2 2 0 Double zinc ribbon Prok-RING_1 PF14446.1 KFH49084.1 - 2 8.2 16.1 3 7.6 0.5 3.0 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 PHD PF00628.24 KFH49084.1 - 7.5 6.3 15.4 0.2 11.3 4.4 2.5 1 1 1 2 2 2 0 PHD-finger PolC_DP2 PF03833.8 KFH49084.1 - 9.7 3.6 6.9 9.9 3.6 4.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 CAF1 PF04857.15 KFH49085.1 - 2.9e-35 121.8 0.0 3.4e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease RNase_T PF00929.19 KFH49085.1 - 0.061 13.6 0.0 1.8 8.7 0.0 2.3 2 0 0 2 2 2 0 Exonuclease DNA_pol_A_exo1 PF01612.15 KFH49085.1 - 0.11 11.9 0.0 1.6 8.1 0.0 2.1 2 0 0 2 2 2 0 3'-5' exonuclease SGL PF08450.7 KFH49086.1 - 7.3e-64 215.4 0.0 9.4e-64 215.1 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 KFH49086.1 - 0.034 14.1 0.0 0.07 13.1 0.0 1.5 1 0 0 1 1 1 0 Arylesterase Reg_prop PF07494.6 KFH49086.1 - 0.11 12.6 0.6 22 5.5 0.0 3.8 3 0 0 3 3 3 0 Two component regulator propeller Cadherin PF00028.12 KFH49086.1 - 0.15 12.3 0.2 2.9 8.2 0.0 2.3 2 0 0 2 2 2 0 Cadherin domain RTA1 PF04479.8 KFH49088.1 - 1.5e-40 139.0 7.2 2.1e-40 138.6 5.0 1.1 1 0 0 1 1 1 1 RTA1 like protein WD40 PF00400.27 KFH49089.1 - 1.5e-21 75.3 9.2 2.6e-08 33.4 0.1 6.4 8 0 0 8 8 8 5 WD domain, G-beta repeat DUF4137 PF13593.1 KFH49091.1 - 1.6e-87 293.5 16.8 1.8e-87 293.3 11.6 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.11 KFH49091.1 - 4.6e-08 32.6 9.8 4.6e-08 32.6 6.8 2.0 2 0 0 2 2 2 1 Sodium Bile acid symporter family DUF342 PF03961.8 KFH49092.1 - 8.9e-05 21.0 1.3 0.00011 20.7 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) Bactofilin PF04519.8 KFH49092.1 - 0.0033 17.3 1.3 0.026 14.5 0.9 2.1 1 1 0 1 1 1 1 Polymer-forming cytoskeletal DUF748 PF05359.6 KFH49092.1 - 0.15 12.0 0.0 9.9 6.1 0.0 2.7 1 1 2 3 3 3 0 Domain of Unknown Function (DUF748) MinC_C PF03775.11 KFH49092.1 - 0.28 10.8 3.4 3.3 7.4 0.7 2.7 1 1 1 2 2 2 0 Septum formation inhibitor MinC, C-terminal domain PUF PF00806.14 KFH49093.1 - 3.1e-30 101.9 6.2 3.2e-05 23.1 0.0 8.8 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat OapA_N PF08525.6 KFH49094.1 - 2.7 7.8 5.1 5.4 6.9 3.6 1.6 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif Nucleoside_tran PF01733.13 KFH49095.1 - 4e-39 134.6 6.0 2.2e-37 128.8 4.1 2.7 1 1 0 1 1 1 1 Nucleoside transporter MFS_1 PF07690.11 KFH49095.1 - 4.2e-07 29.0 29.1 0.00043 19.0 2.6 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily HK PF02110.10 KFH49096.1 - 1.8e-76 256.5 5.2 2.8e-76 255.9 3.6 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 KFH49096.1 - 3.1e-58 195.8 1.8 6.8e-58 194.7 1.2 1.6 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Phos_pyr_kin PF08543.7 KFH49096.1 - 0.00017 20.8 2.0 0.00026 20.2 0.1 2.0 1 1 0 2 2 2 1 Phosphomethylpyrimidine kinase Zn_clus PF00172.13 KFH49097.1 - 3.7e-13 49.1 30.9 1.9e-07 30.8 8.8 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFH49097.1 - 1e-12 47.5 0.6 1.5e-12 46.9 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Haem_bd PF14376.1 KFH49097.1 - 0.24 11.0 4.1 0.051 13.2 0.4 1.7 2 0 0 2 2 2 0 Haem-binding domain TMEM171 PF15471.1 KFH49097.1 - 0.95 8.1 9.5 2.1 7.0 6.6 1.5 1 0 0 1 1 1 0 Transmembrane protein family 171 DnaJ PF00226.26 KFH49099.1 - 8.7e-14 51.0 1.5 1.2e-12 47.3 0.0 3.0 3 0 0 3 3 3 1 DnaJ domain CTK3 PF12243.3 KFH49100.1 - 1.5e-57 193.1 0.2 2e-57 192.7 0.1 1.1 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 KFH49100.1 - 1e-19 70.3 6.1 2.6e-19 69.0 4.2 1.7 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus MAM33 PF02330.11 KFH49100.1 - 0.052 13.3 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial glycoprotein FYDLN_acid PF09538.5 KFH49100.1 - 0.86 10.2 4.3 0.72 10.4 1.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF2397 PF09660.5 KFH49100.1 - 1.2 7.5 7.7 13 4.2 2.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2397) GFA PF04828.9 KFH49101.1 - 0.0046 16.8 0.0 0.0083 16.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 KFH49101.1 - 0.059 12.5 0.4 0.13 11.4 0.3 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Catalase PF00199.14 KFH49103.1 - 8.5e-160 531.6 0.3 1.2e-159 531.1 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KFH49103.1 - 1.9e-20 72.4 0.0 4.2e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Eno-Rase_FAD_bd PF07055.7 KFH49103.1 - 0.057 13.3 0.1 2.1 8.3 0.1 2.7 2 0 0 2 2 2 0 Enoyl reductase FAD binding domain Isochorismatase PF00857.15 KFH49104.1 - 2.3e-20 73.2 0.5 7.9e-20 71.4 0.4 1.7 1 1 0 1 1 1 1 Isochorismatase family Biotin_lipoyl PF00364.17 KFH49105.1 - 5.9e-21 73.8 0.5 1.2e-20 72.8 0.4 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KFH49105.1 - 1.1e-06 28.1 0.1 1.1e-06 28.1 0.0 2.8 3 0 0 3 3 3 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 KFH49105.1 - 0.00033 20.2 0.1 0.0015 18.1 0.0 2.2 2 0 0 2 2 2 1 Biotin-lipoyl like QRPTase_N PF02749.11 KFH49105.1 - 0.016 15.0 0.0 0.04 13.7 0.0 1.7 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain HlyD_2 PF12700.2 KFH49105.1 - 0.026 13.6 0.6 6.1 5.8 0.4 2.2 1 1 1 2 2 2 0 HlyD family secretion protein DUF1640 PF07798.6 KFH49106.1 - 1.4e-13 51.2 3.7 1.9e-13 50.8 2.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Sec2p PF06428.6 KFH49106.1 - 0.0052 16.5 1.6 0.0052 16.5 1.1 2.6 3 0 0 3 3 3 1 GDP/GTP exchange factor Sec2p DUF1191 PF06697.7 KFH49106.1 - 0.044 12.6 0.2 0.063 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Pneumo_att_G PF05539.6 KFH49106.1 - 0.16 11.3 8.2 0.23 10.7 5.7 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G TPR_14 PF13428.1 KFH49107.1 - 4.6e-09 36.1 14.9 0.0096 16.4 0.1 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFH49107.1 - 1.5e-06 27.6 9.0 0.033 14.1 0.0 6.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFH49107.1 - 3.3e-06 27.6 15.6 0.051 14.2 0.3 6.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFH49107.1 - 3.6e-06 26.3 0.3 0.00031 20.3 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFH49107.1 - 3.8e-06 26.6 0.8 0.0064 16.6 0.0 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFH49107.1 - 8.4e-06 26.0 3.7 0.0032 17.7 0.0 4.5 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFH49107.1 - 1.8e-05 24.5 6.9 0.36 10.8 0.2 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFH49107.1 - 5.3e-05 22.7 5.4 0.29 10.8 0.7 4.5 4 1 1 5 5 5 3 TPR repeat TPR_1 PF00515.23 KFH49107.1 - 0.00018 20.9 2.0 0.4 10.3 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFH49107.1 - 0.0011 18.6 8.4 1.7 8.6 0.0 5.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFH49107.1 - 0.46 11.0 0.0 0.46 11.0 0.0 3.9 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 KFH49107.1 - 1.2 8.9 9.5 7.1 6.5 0.6 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat Apc3 PF12895.2 KFH49107.1 - 5.9 7.0 5.7 26 5.0 0.0 4.0 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 AAA_5 PF07728.9 KFH49108.1 - 2.5e-125 412.7 0.0 1.6e-21 76.5 0.0 9.7 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KFH49108.1 - 1.8e-30 105.2 0.0 7.7e-10 38.4 0.0 7.3 8 0 0 8 8 7 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 KFH49108.1 - 3.7e-29 101.5 0.0 9.2e-05 22.6 0.0 7.0 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFH49108.1 - 5.2e-23 81.9 15.4 0.00018 21.5 0.0 9.0 8 1 0 8 8 6 5 AAA ATPase domain AAA_33 PF13671.1 KFH49108.1 - 9.7e-22 77.3 0.0 0.0006 19.6 0.0 8.1 7 1 0 7 7 7 4 AAA domain AAA_22 PF13401.1 KFH49108.1 - 4.8e-21 75.2 1.4 0.012 15.7 0.0 9.3 9 0 0 9 9 7 5 AAA domain AAA_17 PF13207.1 KFH49108.1 - 9.1e-21 74.9 12.5 0.0021 18.8 0.0 8.7 10 0 0 10 10 5 4 AAA domain Sigma54_activ_2 PF14532.1 KFH49108.1 - 3.2e-20 72.5 0.8 7.3e-05 22.8 0.1 7.1 7 0 0 7 7 6 3 Sigma-54 interaction domain AAA_14 PF13173.1 KFH49108.1 - 4.8e-18 65.2 0.0 0.00097 19.0 0.0 7.0 6 0 0 6 6 6 4 AAA domain Sigma54_activat PF00158.21 KFH49108.1 - 5.1e-18 65.1 0.0 0.0034 16.8 0.1 6.0 5 0 0 5 5 5 4 Sigma-54 interaction domain UPF0079 PF02367.12 KFH49108.1 - 1.7e-17 63.2 2.6 0.0071 15.9 0.1 5.5 5 0 0 5 5 5 4 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 KFH49108.1 - 2.1e-16 60.3 7.2 0.002 18.4 0.0 7.0 6 0 0 6 6 5 3 AAA domain AAA_19 PF13245.1 KFH49108.1 - 2.8e-15 55.8 3.6 0.0059 16.3 0.0 6.6 6 0 0 6 6 6 3 Part of AAA domain T2SE PF00437.15 KFH49108.1 - 3.2e-15 55.7 1.8 0.0097 14.8 0.0 6.3 6 0 0 6 6 6 3 Type II/IV secretion system protein NACHT PF05729.7 KFH49108.1 - 6.6e-14 51.9 2.1 0.091 12.4 0.0 6.1 5 0 0 5 5 5 4 NACHT domain RuvB_N PF05496.7 KFH49108.1 - 8.3e-13 47.9 2.4 0.0054 15.7 0.0 6.2 6 0 0 6 6 6 3 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 KFH49108.1 - 1.1e-12 47.4 2.7 0.16 11.0 0.0 6.4 6 0 0 6 6 6 3 Zeta toxin RNA_helicase PF00910.17 KFH49108.1 - 1.2e-12 47.9 0.4 0.12 12.5 0.0 6.5 6 0 0 6 6 6 2 RNA helicase AAA_25 PF13481.1 KFH49108.1 - 2.7e-11 43.2 0.3 0.42 9.9 0.0 5.2 4 0 0 4 4 4 4 AAA domain AAA_28 PF13521.1 KFH49108.1 - 7.3e-11 42.2 3.0 0.19 11.6 0.0 7.2 7 0 0 7 7 6 1 AAA domain DUF258 PF03193.11 KFH49108.1 - 9.7e-11 41.1 1.9 0.017 14.3 0.1 5.8 6 0 0 6 6 6 2 Protein of unknown function, DUF258 ABC_tran PF00005.22 KFH49108.1 - 1.5e-09 38.2 9.2 0.052 13.8 0.0 6.9 7 0 0 7 7 5 2 ABC transporter MobB PF03205.9 KFH49108.1 - 1.6e-09 37.6 0.9 0.46 10.1 0.0 6.1 6 0 0 6 6 6 2 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 KFH49108.1 - 6.2e-09 35.5 0.1 0.56 9.6 0.0 6.0 6 0 0 6 6 6 2 IstB-like ATP binding protein NTPase_1 PF03266.10 KFH49108.1 - 6.6e-09 35.6 4.1 0.99 9.0 0.0 6.3 6 0 0 6 6 6 2 NTPase Arch_ATPase PF01637.13 KFH49108.1 - 1.2e-08 34.9 0.0 2.1 7.9 0.0 6.5 6 0 0 6 6 6 1 Archaeal ATPase AAA_29 PF13555.1 KFH49108.1 - 1.6e-08 33.9 0.1 1.1 8.8 0.0 6.3 6 0 0 6 6 5 1 P-loop containing region of AAA domain Mg_chelatase PF01078.16 KFH49108.1 - 2e-08 33.6 0.5 8.1 5.5 0.0 7.8 8 0 0 8 8 7 0 Magnesium chelatase, subunit ChlI PduV-EutP PF10662.4 KFH49108.1 - 9.9e-08 31.5 1.7 0.058 12.8 0.0 5.1 5 0 0 5 5 5 2 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.17 KFH49108.1 - 2.3e-07 30.4 2.3 0.95 8.8 0.0 5.3 6 0 0 6 6 5 2 SRP54-type protein, GTPase domain Miro PF08477.8 KFH49108.1 - 2.7e-07 31.0 6.4 6.4 7.3 0.0 6.7 7 0 0 7 7 5 0 Miro-like protein cobW PF02492.14 KFH49108.1 - 8e-07 28.6 2.1 3.3 7.1 0.0 6.0 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 KFH49108.1 - 1.9e-06 26.9 4.5 1.3 7.7 0.0 5.4 5 0 0 5 5 5 1 NB-ARC domain TIP49 PF06068.8 KFH49108.1 - 5.5e-06 25.3 1.3 2.6 6.6 0.0 5.1 5 0 0 5 5 5 1 TIP49 C-terminus Viral_helicase1 PF01443.13 KFH49108.1 - 9e-06 25.3 0.1 0.88 9.0 0.0 5.2 6 0 0 6 6 6 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.10 KFH49108.1 - 0.0002 20.2 0.5 0.79 8.3 0.0 4.0 4 0 0 4 4 4 1 Rad17 cell cycle checkpoint protein MMR_HSR1 PF01926.18 KFH49108.1 - 0.00027 20.8 0.2 44 4.0 0.0 5.5 5 0 0 5 5 5 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KFH49108.1 - 0.0004 20.0 1.7 18 4.7 0.0 5.0 5 0 0 5 5 5 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.2 KFH49108.1 - 0.00053 19.1 1.2 3 6.8 0.0 4.0 4 0 0 4 4 4 1 P-loop containing dynein motor region D3 KaiC PF06745.8 KFH49108.1 - 0.0018 17.4 0.1 12 4.9 0.0 4.4 4 0 0 4 4 4 0 KaiC ArgK PF03308.11 KFH49108.1 - 0.0019 17.0 0.9 0.54 8.9 0.0 3.5 3 0 0 3 3 3 1 ArgK protein KTI12 PF08433.5 KFH49108.1 - 0.002 17.4 0.0 1.5 7.9 0.0 4.1 4 0 0 4 4 4 1 Chromatin associated protein KTI12 CbiA PF01656.18 KFH49108.1 - 0.0029 17.0 0.4 1.9 7.8 0.0 4.2 4 0 0 4 4 4 1 CobQ/CobB/MinD/ParA nucleotide binding domain PhoH PF02562.11 KFH49108.1 - 0.0099 15.1 1.0 5.1 6.2 0.0 4.5 5 0 0 5 5 5 0 PhoH-like protein ATP-synt_ab PF00006.20 KFH49108.1 - 0.011 15.2 0.0 9.7 5.6 0.0 4.5 4 1 0 4 4 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_6 PF12774.2 KFH49108.1 - 0.054 13.0 0.0 22 4.4 0.0 4.7 6 0 0 6 6 5 0 Hydrolytic ATP binding site of dynein motor region D1 AAA_11 PF13086.1 KFH49108.1 - 4.4 6.8 26.8 0.91 9.0 0.0 7.8 10 1 0 10 10 6 0 AAA domain VPS9 PF02204.13 KFH49109.1 - 6.4e-21 74.3 0.0 1.3e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Asparaginase_2 PF01112.13 KFH49109.1 - 0.58 8.8 2.7 0.59 8.8 0.9 1.5 2 0 0 2 2 2 0 Asparaginase Spt20 PF12090.3 KFH49109.1 - 0.72 9.1 5.7 0.7 9.2 1.1 2.2 2 0 0 2 2 2 0 Spt20 family DDHD PF02862.12 KFH49109.1 - 2.7 7.7 11.1 1.9 8.2 0.6 2.5 2 0 0 2 2 2 0 DDHD domain RAB3GAP2_N PF14655.1 KFH49109.1 - 9.7 5.0 13.1 0.31 9.9 2.6 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus