# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- CBM_1 PF00734.18 KXL41305.1 - 1.5e-12 47.3 11.1 1.5e-12 47.3 11.1 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain SNase PF00565.17 KXL41306.1 - 5.2e-23 81.6 0.1 9.3e-23 80.8 0.1 1.4 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Ribosomal_S13_N PF08069.12 KXL41307.1 - 8.4e-30 102.6 0.1 1.4e-29 101.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KXL41307.1 - 1.4e-15 57.3 0.2 1.8e-15 56.9 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 KXL41307.1 - 0.018 15.0 0.1 0.044 13.7 0.0 1.7 2 0 0 2 2 2 0 'Paired box' domain Topoisom_I PF01028.20 KXL41308.1 - 1.1e-97 325.9 5.7 1.1e-97 325.9 5.7 2.0 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 KXL41308.1 - 5.6e-96 320.1 4.7 5.6e-96 320.1 4.7 4.1 4 1 0 5 5 5 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 KXL41308.1 - 9.9e-33 111.9 0.4 3.5e-32 110.1 0.4 2.1 1 0 0 1 1 1 1 C-terminal topoisomerase domain ATP-synt PF00231.19 KXL41309.1 - 3e-81 273.2 2.6 3.6e-81 272.9 2.6 1.0 1 0 0 1 1 1 1 ATP synthase Fungal_trans PF04082.18 KXL41310.1 - 9.1e-11 41.3 0.1 1.6e-10 40.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL41310.1 - 6.7e-08 32.5 10.8 1.3e-07 31.7 10.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF922 PF06037.11 KXL41310.1 - 0.19 11.5 0.4 1.1 9.0 0.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF922) Sugar_tr PF00083.24 KXL41311.1 - 8.3e-116 387.5 26.6 1e-115 387.2 26.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL41311.1 - 1.2e-22 80.3 36.0 4e-21 75.3 19.9 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily Pal1 PF08316.11 KXL41313.1 - 6.3e-07 30.2 1.6 1.5e-06 29.0 0.1 2.1 2 0 0 2 2 2 1 Pal1 cell morphology protein HVSL PF09749.9 KXL41314.1 - 5.7e-79 264.9 0.0 7.7e-79 264.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein COesterase PF00135.28 KXL41315.1 - 2e-78 264.5 0.0 2.8e-78 264.1 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXL41315.1 - 6.7e-05 22.8 0.5 0.09 12.6 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXL41315.1 - 0.022 14.2 0.3 0.039 13.4 0.3 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family HA2 PF04408.23 KXL41316.1 - 7.3e-19 68.1 0.0 2.4e-18 66.4 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KXL41316.1 - 7.5e-19 67.9 0.0 1.6e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KXL41316.1 - 2.2e-14 53.7 0.0 4e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain WD40 PF00400.32 KXL41317.1 - 9.3e-11 42.1 6.3 0.18 12.7 0.8 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.8 KXL41317.1 - 9.9e-06 24.5 2.7 0.2 10.3 0.0 3.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KXL41317.1 - 1.5e-05 25.2 0.2 0.22 11.8 0.1 4.3 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KXL41317.1 - 0.036 14.5 0.0 0.61 10.6 0.0 3.0 4 0 0 4 4 4 0 PQQ-like domain VRR_NUC PF08774.11 KXL41318.1 - 2.9e-21 75.6 0.0 8.1e-21 74.1 0.0 1.8 1 0 0 1 1 1 1 VRR-NUC domain RRM_1 PF00076.22 KXL41319.1 - 4.4e-07 29.6 0.0 5.5e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXL41319.1 - 0.07 13.1 0.0 0.08 13.0 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif APH PF01636.23 KXL41320.1 - 2.3e-42 145.6 0.0 4.2e-42 144.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KXL41320.1 - 9.3e-07 28.4 0.0 2.3e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 KXL41320.1 - 0.00026 20.6 0.0 0.00042 20.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KXL41320.1 - 0.0071 16.0 0.0 0.095 12.3 0.0 2.2 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 KXL41320.1 - 0.017 14.5 0.0 0.075 12.4 0.0 2.0 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.11 KXL41320.1 - 0.055 12.3 0.0 0.08 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) CAP_GLY PF01302.25 KXL41321.1 - 6.4e-18 64.5 1.3 1.2e-17 63.6 1.3 1.5 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 KXL41321.1 - 0.00058 19.7 0.8 0.00058 19.7 0.8 3.0 2 1 0 2 2 2 1 CLIP1 zinc knuckle Wtap PF17098.5 KXL41321.1 - 0.01 15.8 27.7 0.13 12.2 22.6 3.3 2 2 0 2 2 2 0 WTAP/Mum2p family HIP1_clath_bdg PF16515.5 KXL41321.1 - 0.021 15.4 33.4 1.2 9.7 0.2 4.7 3 1 2 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 zf-CCHC PF00098.23 KXL41321.1 - 0.082 13.0 0.4 0.16 12.1 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle Sec8_exocyst PF04048.14 KXL41321.1 - 0.17 11.8 12.1 2 8.3 4.7 3.7 4 0 0 4 4 4 0 Sec8 exocyst complex component specific domain DUF4407 PF14362.6 KXL41321.1 - 0.27 10.5 18.5 0.28 10.5 5.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) zf-CCHC_3 PF13917.6 KXL41321.1 - 0.35 10.9 4.0 2.5 8.1 0.8 2.7 2 0 0 2 2 2 0 Zinc knuckle Pantoate_ligase PF02569.15 KXL41321.1 - 0.52 9.5 3.6 0.39 9.9 2.1 1.5 2 0 0 2 2 2 0 Pantoate-beta-alanine ligase Spc7 PF08317.11 KXL41321.1 - 0.59 9.0 33.7 1.7 7.4 15.7 3.3 2 1 1 3 3 3 0 Spc7 kinetochore protein End3 PF12761.7 KXL41321.1 - 1.2 9.3 27.6 2.9 8.0 14.0 3.3 2 1 1 3 3 3 0 Actin cytoskeleton-regulatory complex protein END3 Fez1 PF06818.15 KXL41321.1 - 2.1 8.8 36.7 0.63 10.5 18.9 3.3 1 1 0 3 3 3 0 Fez1 TPR_MLP1_2 PF07926.12 KXL41321.1 - 3.1 7.9 41.3 0.96 9.5 9.6 4.2 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.12 KXL41321.1 - 4.2 7.9 12.7 8.4 6.9 1.7 4.0 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein EzrA PF06160.12 KXL41321.1 - 5.4 5.1 20.9 0.35 9.0 0.6 3.0 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA CytochromB561_N PF09786.9 KXL41321.1 - 5.5 5.9 8.0 11 4.8 8.0 1.5 1 0 0 1 1 1 0 Cytochrome B561, N terminal GAS PF13851.6 KXL41321.1 - 6.5 6.0 32.4 0.65 9.3 1.2 4.2 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding MCPsignal PF00015.21 KXL41321.1 - 7 6.4 11.7 1.4 8.7 0.5 3.0 2 1 1 4 4 4 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Aminotran_1_2 PF00155.21 KXL41322.1 - 2.5e-17 63.1 0.0 3.2e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KXL41322.1 - 4e-06 25.9 0.0 1e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.17 KXL41322.1 - 0.0013 18.1 0.2 0.013 14.8 0.1 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family LSM PF01423.22 KXL41323.1 - 3.7e-22 77.8 0.1 4.3e-22 77.6 0.1 1.1 1 0 0 1 1 1 1 LSM domain adh_short PF00106.25 KXL41324.1 - 5.9e-33 114.0 0.1 7.7e-33 113.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL41324.1 - 1.3e-27 96.8 0.0 1.7e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KXL41324.1 - 0.024 14.1 0.1 0.052 13.0 0.1 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family APG6 PF04111.12 KXL41325.1 - 2.6e-64 216.5 0.0 4.1e-64 215.8 0.0 1.3 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 KXL41325.1 - 1e-35 123.1 24.0 2.2e-35 122.1 24.0 1.6 1 0 0 1 1 1 1 Apg6 coiled-coil region FUSC PF04632.12 KXL41325.1 - 0.018 13.6 7.2 0.026 13.1 7.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family zf-C4H2 PF10146.9 KXL41325.1 - 0.019 15.3 7.4 0.036 14.4 7.4 1.5 1 0 0 1 1 1 0 Zinc finger-containing protein SUKH-4 PF14435.6 KXL41325.1 - 0.083 12.9 1.6 1.6 8.7 1.7 2.2 2 0 0 2 2 2 0 SUKH-4 immunity protein YabA PF06156.13 KXL41325.1 - 0.09 13.4 7.5 0.034 14.8 3.8 2.1 1 1 1 2 2 2 0 Initiation control protein YabA FapA PF03961.13 KXL41325.1 - 0.26 9.8 9.5 0.18 10.4 7.1 1.7 1 1 1 2 2 2 0 Flagellar Assembly Protein A V_ATPase_I PF01496.19 KXL41325.1 - 0.27 9.1 6.7 0.4 8.5 6.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TPR_MLP1_2 PF07926.12 KXL41325.1 - 0.39 10.8 23.7 0.89 9.6 23.7 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Sec34 PF04136.15 KXL41325.1 - 0.8 9.6 10.2 0.43 10.5 7.2 2.0 2 0 0 2 2 2 0 Sec34-like family DUF16 PF01519.16 KXL41325.1 - 1.3 9.6 8.5 3 8.4 7.1 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 HAUS-augmin3 PF14932.6 KXL41325.1 - 1.4 8.5 16.9 0.98 8.9 14.9 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 GAS PF13851.6 KXL41325.1 - 1.8 7.9 24.5 1.2 8.4 15.0 2.6 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 KXL41325.1 - 2.4 8.2 6.9 1.3 9.1 3.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 KXL41325.1 - 6.2 7.1 17.1 3.7 7.8 13.5 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Cep57_CLD_2 PF14197.6 KXL41325.1 - 8.4 6.6 19.6 50 4.1 0.0 3.0 1 1 1 3 3 3 0 Centrosome localisation domain of PPC89 CorA PF01544.18 KXL41325.1 - 9 5.5 6.9 1.4e+02 1.6 2.5 2.3 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein LUC7 PF03194.15 KXL41325.1 - 9.1 5.9 15.9 10 5.7 14.3 1.7 1 1 1 2 2 2 0 LUC7 N_terminus Myb_DNA-bind_6 PF13921.6 KXL41326.1 - 1.4e-23 82.9 0.2 0.0066 16.7 0.0 6.8 6 0 0 6 6 6 6 Myb-like DNA-binding domain Scm3 PF10384.9 KXL41326.1 - 3.8e-22 77.8 0.2 1.3e-21 76.1 0.2 2.0 1 0 0 1 1 1 1 Centromere protein Scm3 Myb_DNA-binding PF00249.31 KXL41326.1 - 3.9e-22 78.2 1.7 0.00074 19.7 0.2 6.0 6 0 0 6 6 6 5 Myb-like DNA-binding domain GATA PF00320.27 KXL41326.1 - 2.6e-07 30.2 4.4 2.6e-07 30.2 4.4 2.0 2 0 0 2 2 2 1 GATA zinc finger Forkhead PF00250.18 KXL41326.1 - 4.8e-07 29.9 0.0 1.2e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Forkhead domain YPEB PF14620.6 KXL41326.1 - 0.018 14.4 0.4 0.03 13.7 0.4 1.3 1 0 0 1 1 1 0 YpeB sporulation CPSase_L_D2 PF02786.17 KXL41327.1 - 4.7e-106 353.0 0.0 9.5e-82 273.6 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KXL41327.1 - 3.7e-41 140.3 0.1 1.5e-40 138.3 0.0 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 KXL41327.1 - 9.5e-20 70.9 0.0 6.5e-11 42.1 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KXL41327.1 - 3.3e-17 62.7 0.2 1.1e-09 38.1 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KXL41327.1 - 1.5e-10 41.0 0.0 0.00057 19.6 0.0 3.3 3 1 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 KXL41327.1 - 8.1e-06 25.4 0.1 0.0073 15.8 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 KXL41327.1 - 8.4e-06 25.7 0.1 0.022 14.5 0.0 2.7 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 KXL41327.1 - 9.7e-06 25.7 0.0 0.022 14.8 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_4 PF13535.6 KXL41327.1 - 0.0081 15.8 0.0 0.033 13.8 0.0 2.1 1 0 0 1 1 1 1 ATP-grasp domain Epimerase PF01370.21 KXL41327.1 - 0.065 12.7 0.0 0.33 10.4 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family CDP-OH_P_transf PF01066.21 KXL41328.1 - 1.7e-14 54.3 0.0 1.7e-14 54.3 0.0 2.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Sugar_tr PF00083.24 KXL41330.1 - 1.3e-120 403.3 24.9 1.5e-120 403.1 24.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL41330.1 - 8.8e-19 67.6 40.3 3.1e-18 65.8 35.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ilm1 PF10311.9 KXL41330.1 - 0.11 12.2 1.5 0.19 11.4 0.6 1.8 2 0 0 2 2 2 0 Increased loss of mitochondrial DNA protein 1 DUF3726 PF12525.8 KXL41330.1 - 1.6 8.9 0.0 1.6 8.9 0.0 2.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3726) HSP70 PF00012.20 KXL41331.1 - 4.4e-228 758.3 9.3 4.9e-228 758.2 9.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXL41331.1 - 1.7e-16 59.9 0.2 2.9e-15 55.9 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KXL41331.1 - 3.5e-05 23.6 0.0 7.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Rhodanese PF00581.20 KXL41332.1 - 4.8e-06 27.0 0.0 8.4e-06 26.3 0.0 1.4 1 1 0 1 1 1 1 Rhodanese-like domain Glyco_hydro_38N PF01074.22 KXL41334.1 - 5.2e-83 278.8 0.8 5.2e-83 278.8 0.8 2.1 3 0 0 3 3 3 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KXL41334.1 - 6.8e-57 193.0 0.2 1.5e-56 191.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KXL41334.1 - 3.3e-29 100.9 0.0 7.1e-29 99.8 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KXL41334.1 - 5.4e-07 29.6 0.0 1.6e-06 28.1 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 KXL41334.1 - 0.083 12.1 0.0 0.22 10.7 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 57 NUDIX PF00293.28 KXL41335.1 - 5.8e-08 32.8 0.1 2.6e-07 30.7 0.0 1.9 1 1 0 2 2 2 1 NUDIX domain ADK PF00406.22 KXL41336.1 - 2.7e-35 121.7 0.0 3.9e-19 69.2 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.14 KXL41336.1 - 2.7e-16 59.3 0.0 4.4e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 KXL41336.1 - 4e-15 56.4 0.0 7.4e-10 39.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KXL41336.1 - 0.0044 17.6 0.0 0.042 14.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXL41336.1 - 0.083 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXL41336.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KXL41336.1 - 0.18 11.8 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) LETM1 PF07766.13 KXL41337.1 - 9.6e-103 343.2 0.4 9.6e-103 343.2 0.4 2.1 3 0 0 3 3 3 1 LETM1-like protein SAP PF02037.27 KXL41337.1 - 0.00046 19.9 0.0 0.07 12.9 0.0 3.8 4 0 0 4 4 4 1 SAP domain Asp-B-Hydro_N PF05279.11 KXL41337.1 - 1.3 9.1 39.8 0.46 10.5 10.3 2.2 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region FA_desaturase PF00487.24 KXL41339.1 - 0.16 11.8 1.9 0.54 10.1 0.6 2.0 1 1 1 2 2 2 0 Fatty acid desaturase zf-RING_2 PF13639.6 KXL41340.1 - 1.7e-12 47.5 6.0 2.5e-12 46.9 6.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXL41340.1 - 1.4e-09 37.5 0.5 2.4e-09 36.8 0.5 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KXL41340.1 - 7.6e-09 35.3 3.9 1.2e-08 34.6 3.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXL41340.1 - 1e-08 34.9 6.3 1.6e-08 34.3 6.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXL41340.1 - 2.4e-07 30.6 3.4 3.9e-07 29.9 3.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KXL41340.1 - 3.8e-06 27.1 9.8 2.4e-05 24.5 9.8 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KXL41340.1 - 3.2e-05 23.9 0.6 3.2e-05 23.9 0.6 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXL41340.1 - 0.00038 20.2 2.8 0.00065 19.5 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KXL41340.1 - 0.0014 18.7 3.2 0.004 17.2 3.2 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KXL41340.1 - 0.018 14.8 6.9 0.031 14.1 6.9 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 KXL41340.1 - 0.024 14.5 6.1 0.051 13.5 6.1 1.6 1 0 0 1 1 1 0 PHD-finger Prok-RING_4 PF14447.6 KXL41340.1 - 0.027 14.3 4.3 0.057 13.3 4.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KXL41340.1 - 0.037 14.2 4.2 0.084 13.1 4.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KXL41340.1 - 0.1 12.2 4.7 0.19 11.4 4.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type OAD_gamma PF04277.13 KXL41340.1 - 0.18 12.4 0.4 0.75 10.4 0.0 2.1 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain RINGv PF12906.7 KXL41340.1 - 0.23 11.6 3.5 0.54 10.4 3.5 1.6 1 1 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.6 KXL41340.1 - 0.44 10.5 8.7 0.52 10.3 6.1 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 KXL41340.1 - 0.57 10.4 4.3 2 8.7 4.3 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 KXL41340.1 - 2 8.5 6.9 4.7 7.3 6.9 1.7 1 1 0 1 1 1 0 Zinc-finger FAD_binding_3 PF01494.19 KXL41341.1 - 2.2e-17 63.3 0.1 7.8e-17 61.5 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXL41341.1 - 6.9e-07 28.8 0.0 0.0052 16.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXL41341.1 - 0.00011 21.1 0.0 0.0034 16.1 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 KXL41341.1 - 0.0002 21.1 0.1 0.025 14.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXL41341.1 - 0.0013 17.9 0.2 0.0041 16.3 0.1 1.7 1 1 1 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KXL41341.1 - 0.0043 17.2 0.0 0.016 15.4 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KXL41341.1 - 0.052 12.9 0.2 0.12 11.7 0.1 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXL41341.1 - 0.12 13.0 0.2 2.4 8.8 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXL41341.1 - 0.13 11.3 0.3 0.73 8.8 0.3 2.0 1 1 0 1 1 1 0 Glucose inhibited division protein A P34-Arc PF04045.14 KXL41342.1 - 3e-108 361.1 0.2 4e-108 360.7 0.2 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.12 KXL41342.1 - 0.014 15.0 0.2 0.035 13.7 0.2 1.6 1 1 0 1 1 1 0 ARP2/3 complex 20 kDa subunit (ARPC4) Metallophos PF00149.28 KXL41343.1 - 4.3e-22 79.6 0.7 7.1e-22 78.9 0.7 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 KXL41343.1 - 3.6e-14 53.4 0.4 9.5e-14 52.0 0.4 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 KXL41343.1 - 7.5e-14 52.1 2.1 2.3e-13 50.5 2.1 1.9 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain PhoD PF09423.10 KXL41343.1 - 0.005 15.9 0.0 0.063 12.3 0.1 2.1 2 0 0 2 2 2 1 PhoD-like phosphatase Metallophos_2 PF12850.7 KXL41343.1 - 0.03 14.5 0.0 0.34 11.1 0.0 2.2 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain PhoD_N PF16655.5 KXL41343.1 - 0.068 13.7 0.1 0.16 12.5 0.1 1.6 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain Bromodomain PF00439.25 KXL41344.1 - 1.2e-35 121.4 0.2 5e-21 74.6 0.3 2.6 2 0 0 2 2 2 2 Bromodomain CKS PF01111.19 KXL41346.1 - 2e-33 114.5 1.0 2e-33 114.5 1.0 1.4 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit AA_synth PF06684.11 KXL41347.1 - 0.1 12.1 0.1 0.36 10.3 0.0 1.8 2 0 0 2 2 2 0 Amino acid synthesis LMBR1 PF04791.16 KXL41349.1 - 1.3e-19 70.5 0.2 1.3e-19 70.5 0.2 2.5 2 1 1 3 3 3 2 LMBR1-like membrane protein Cytomega_TRL10 PF06084.11 KXL41349.1 - 0.51 10.3 1.5 15 5.6 0.3 2.8 2 1 0 2 2 2 0 Cytomegalovirus TRL10 protein DUF3671 PF12420.8 KXL41349.1 - 2 8.5 9.7 14 5.8 1.3 3.7 3 1 0 3 3 3 0 Protein of unknown function CPSF_A PF03178.15 KXL41350.1 - 2e-58 198.3 0.0 5.1e-58 196.9 0.0 1.7 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 KXL41350.1 - 8.3e-15 54.4 0.0 1.5e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF1633 PF07794.11 KXL41351.1 - 0.029 12.6 2.5 0.029 12.6 2.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) Amidase PF01425.21 KXL41352.1 - 1.1e-54 186.1 1.7 1.4e-54 185.8 1.7 1.1 1 0 0 1 1 1 1 Amidase DUF2235 PF09994.9 KXL41353.1 - 1.8e-42 145.7 0.0 2.8e-42 145.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) MMR_HSR1 PF01926.23 KXL41353.1 - 1.2e-07 31.8 0.0 2.9e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 KXL41353.1 - 5.4e-06 26.6 0.0 1.6e-05 25.1 0.0 1.8 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KXL41353.1 - 4e-05 23.3 0.4 0.00011 21.8 0.4 1.7 1 1 0 1 1 1 1 Ras family Septin PF00735.18 KXL41353.1 - 0.00017 21.0 0.5 0.016 14.5 0.0 2.2 2 0 0 2 2 2 1 Septin Gtr1_RagA PF04670.12 KXL41353.1 - 0.0016 17.8 0.1 0.0028 17.0 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Palm_thioest PF02089.15 KXL41353.1 - 0.0055 16.6 0.1 0.014 15.3 0.0 1.6 2 0 0 2 2 2 1 Palmitoyl protein thioesterase RsgA_GTPase PF03193.16 KXL41353.1 - 0.0056 16.6 2.0 0.025 14.5 0.2 2.2 2 0 0 2 2 2 1 RsgA GTPase Arf PF00025.21 KXL41353.1 - 0.0097 15.4 0.3 0.072 12.5 0.3 2.2 1 1 0 1 1 1 1 ADP-ribosylation factor family Dynamin_N PF00350.23 KXL41353.1 - 0.011 15.8 0.8 0.056 13.5 0.1 2.5 4 0 0 4 4 3 0 Dynamin family AAA_29 PF13555.6 KXL41353.1 - 0.016 14.9 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain OxoDH_E1alpha_N PF12573.8 KXL41353.1 - 0.063 13.0 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal DUF3375 PF11855.8 KXL41353.1 - 0.067 12.1 1.8 1.1 8.0 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3375) GTP_EFTU PF00009.27 KXL41353.1 - 0.096 12.2 1.1 2.8 7.5 0.1 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DLIC PF05783.11 KXL41353.1 - 0.11 11.3 0.1 0.23 10.2 0.1 1.5 1 1 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_22 PF13401.6 KXL41353.1 - 0.12 12.6 0.6 0.48 10.7 0.6 2.0 1 1 0 1 1 1 0 AAA domain AIG1 PF04548.16 KXL41353.1 - 0.14 11.5 0.1 0.29 10.4 0.1 1.5 1 0 0 1 1 1 0 AIG1 family T2SSE PF00437.20 KXL41353.1 - 0.15 11.1 0.1 0.28 10.2 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 KXL41353.1 - 0.16 11.3 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.27 KXL41353.1 - 0.16 12.4 0.0 0.49 10.9 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 KXL41353.1 - 0.24 11.9 5.1 0.73 10.3 5.1 1.7 1 1 0 1 1 1 0 AAA domain DUF2417 PF10329.9 KXL41354.1 - 3.3e-83 278.7 0.0 4.4e-83 278.3 0.0 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) SRF-TF PF00319.18 KXL41354.1 - 0.12 11.8 0.1 0.32 10.5 0.1 1.7 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) Spo7 PF03907.13 KXL41354.1 - 0.4 10.1 3.1 1.1 8.7 1.6 2.1 2 0 0 2 2 2 0 Spo7-like protein SLATT_5 PF18160.1 KXL41354.1 - 2.2 7.6 4.3 2.5 7.4 1.9 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 PX PF00787.24 KXL41356.1 - 7.6e-19 67.8 0.0 8e-19 67.7 0.0 1.0 1 0 0 1 1 1 1 PX domain Sec1 PF00995.23 KXL41357.1 - 2e-113 380.7 0.0 2.2e-113 380.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family tRNA-synt_His PF13393.6 KXL41358.1 - 9e-36 123.7 0.0 1e-29 103.8 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KXL41358.1 - 1.8e-13 50.4 0.0 4.2e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.20 KXL41358.1 - 0.00011 21.5 0.0 0.00042 19.5 0.0 1.6 1 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 KXL41358.1 - 0.00027 20.9 0.0 0.001 19.1 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon2 PF12745.7 KXL41358.1 - 0.089 12.3 0.0 0.42 10.1 0.0 1.9 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs Peptidase_M20 PF01546.28 KXL41359.1 - 3.1e-33 115.2 0.0 7.8e-33 113.9 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXL41359.1 - 6.4e-15 55.0 0.3 1.5e-14 53.8 0.1 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KXL41359.1 - 0.021 14.5 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 AATase PF07247.12 KXL41360.1 - 4e-11 42.2 0.0 2e-10 39.9 0.0 2.0 2 1 0 2 2 2 1 Alcohol acetyltransferase WES_acyltransf PF03007.16 KXL41360.1 - 0.0055 16.5 0.0 0.017 14.9 0.0 1.7 1 1 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain PWI PF01480.17 KXL41361.1 - 6.3e-24 84.1 0.0 9.2e-24 83.6 0.0 1.3 1 0 0 1 1 1 1 PWI domain CEBP_ZZ PF16366.5 KXL41363.1 - 7.8 6.8 9.2 0.86 9.9 4.5 1.8 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain HpcH_HpaI PF03328.14 KXL41364.1 - 3.3e-42 144.1 0.0 5.3e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KXL41364.1 - 7.1e-11 41.8 0.0 2.5e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold RexA PF15969.5 KXL41364.1 - 0.23 11.0 0.0 0.77 9.3 0.0 1.8 2 0 0 2 2 2 0 Intracellular sensor of Lambda phage, Abi component DUF846 PF05832.12 KXL41365.1 - 4.2e-51 172.6 7.0 4.9e-51 172.4 7.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF5504 PF17608.2 KXL41365.1 - 0.027 14.5 1.0 0.027 14.5 1.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5504) TcpE PF12648.7 KXL41365.1 - 0.048 14.2 6.2 0.059 13.9 0.8 2.1 2 0 0 2 2 2 0 TcpE family TMEM220 PF15071.6 KXL41365.1 - 0.053 14.3 1.0 0.19 12.5 0.1 2.0 2 0 0 2 2 2 0 Transmembrane family 220, helix DUF4191 PF13829.6 KXL41365.1 - 0.09 12.1 5.9 0.55 9.5 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Mannosyl_trans3 PF11051.8 KXL41366.1 - 1.4e-31 109.9 0.0 9.1e-23 81.0 0.0 2.2 1 1 1 2 2 2 2 Mannosyltransferase putative Aldolase_II PF00596.21 KXL41367.1 - 1.5e-44 152.2 0.0 2.9e-44 151.2 0.0 1.5 1 1 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain ResIII PF04851.15 KXL41368.1 - 5.1e-19 68.9 0.0 1.1e-18 67.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXL41368.1 - 7.9e-19 68.1 0.0 2.8e-18 66.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXL41368.1 - 4.4e-14 52.6 0.0 9.4e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 KXL41368.1 - 0.032 13.4 0.2 1.9 7.7 0.0 2.4 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 KXL41368.1 - 0.035 14.4 0.0 0.88 9.8 0.0 2.8 2 1 0 2 2 2 0 AAA domain GFA PF04828.14 KXL41369.1 - 5.3e-13 49.1 0.0 8.1e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme OPA3 PF07047.12 KXL41370.1 - 1.2e-44 151.1 10.6 1.7e-44 150.6 10.6 1.3 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) RR_TM4-6 PF06459.12 KXL41370.1 - 0.078 12.8 4.3 0.099 12.5 4.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TetR_C_28 PF17937.1 KXL41370.1 - 0.21 12.1 3.0 3.8 8.0 0.2 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Selenoprotein_S PF06936.11 KXL41370.1 - 0.4 10.5 8.4 0.42 10.4 7.7 1.4 2 0 0 2 2 2 0 Selenoprotein S (SelS) Presenilin PF01080.17 KXL41370.1 - 0.73 8.5 2.7 0.84 8.3 2.7 1.1 1 0 0 1 1 1 0 Presenilin NECFESHC PF16621.5 KXL41371.1 - 1.1 9.3 5.8 9.4 6.3 0.6 3.0 3 0 0 3 3 3 0 SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1 ANAPC_CDC26 PF10471.9 KXL41372.1 - 1.3e-13 51.5 3.0 1.4e-13 51.4 3.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 TMIE PF16038.5 KXL41372.1 - 0.14 12.0 0.1 0.15 11.9 0.1 1.1 1 0 0 1 1 1 0 TMIE protein Rep_fac_C PF08542.11 KXL41374.1 - 9.3e-19 67.6 0.1 1.8e-18 66.7 0.1 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 KXL41374.1 - 8.8e-15 55.3 0.0 2.2e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KXL41374.1 - 1.5e-12 47.6 0.0 4.8e-08 33.0 0.0 2.9 3 0 0 3 3 3 2 DNA polymerase III, delta subunit Rad17 PF03215.15 KXL41374.1 - 4.1e-09 36.6 0.0 9.6e-09 35.4 0.0 1.6 2 0 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 KXL41374.1 - 1e-05 25.3 0.0 3.4e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXL41374.1 - 1.4e-05 25.4 0.0 7.9e-05 23.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXL41374.1 - 2.1e-05 25.0 0.3 0.00081 19.8 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_assoc_2 PF16193.5 KXL41374.1 - 3.3e-05 24.1 0.4 0.00011 22.4 0.4 2.0 1 0 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 KXL41374.1 - 4.6e-05 23.3 0.0 7.2e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KXL41374.1 - 0.00012 21.6 0.0 0.0063 15.9 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KXL41374.1 - 0.0027 17.4 0.0 0.011 15.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXL41374.1 - 0.0036 17.3 0.1 0.038 14.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KXL41374.1 - 0.0041 16.3 0.0 0.0065 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DNA_pol3_delta PF06144.13 KXL41374.1 - 0.013 15.3 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_19 PF13245.6 KXL41374.1 - 0.014 15.7 0.0 0.098 13.0 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KXL41374.1 - 0.016 15.3 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 KXL41374.1 - 0.02 14.9 0.0 0.097 12.7 0.0 2.1 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 KXL41374.1 - 0.022 14.3 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 KXL41374.1 - 0.023 14.9 0.0 0.069 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KXL41374.1 - 0.039 13.0 0.0 0.061 12.4 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_18 PF13238.6 KXL41374.1 - 0.048 14.2 0.0 0.16 12.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KXL41374.1 - 0.067 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.11 KXL41374.1 - 0.077 12.9 0.0 0.9 9.4 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KXL41374.1 - 0.098 12.8 0.0 0.49 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 KXL41374.1 - 0.12 12.1 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase RNA_helicase PF00910.22 KXL41374.1 - 0.16 12.4 0.0 0.41 11.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Glyco_hydro_43 PF04616.14 KXL41375.1 - 5.5e-11 42.3 0.7 1.1e-10 41.3 0.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 WD40 PF00400.32 KXL41376.1 - 4.5e-51 169.7 28.1 1.1e-06 29.2 0.2 12.5 12 1 0 12 12 11 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL41376.1 - 6.8e-21 74.4 4.1 0.0014 18.9 0.0 9.6 4 3 7 11 11 11 7 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KXL41376.1 - 3.4e-18 65.9 0.3 7.1e-18 64.9 0.3 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.8 KXL41376.1 - 2.5e-08 33.0 7.4 0.64 8.6 0.0 7.6 6 1 2 8 8 8 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KXL41376.1 - 5.2e-08 32.2 3.9 1.6 7.6 0.0 7.0 3 1 5 8 8 8 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KXL41376.1 - 0.0001 21.2 3.4 0.26 10.0 0.1 4.8 1 1 5 6 6 6 1 Nup133 N terminal like WD40_like PF17005.5 KXL41376.1 - 0.00027 20.4 0.0 0.43 9.8 0.0 3.3 3 1 0 3 3 3 2 WD40-like domain eIF2A PF08662.11 KXL41376.1 - 0.00099 19.0 0.0 6.5 6.6 0.0 4.5 4 1 1 5 5 5 1 Eukaryotic translation initiation factor eIF2A HPS3_N PF14761.6 KXL41376.1 - 0.033 13.7 0.2 43 3.5 0.0 4.9 4 1 3 7 7 7 0 Hermansky-Pudlak syndrome 3 Peptidase_C107 PF17222.3 KXL41376.1 - 0.11 11.5 0.0 0.21 10.5 0.0 1.5 1 0 0 1 1 1 0 Viral cysteine endopeptidase C107 PALB2_WD40 PF16756.5 KXL41376.1 - 0.13 11.2 1.1 22 3.8 0.0 3.7 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain PQQ_2 PF13360.6 KXL41376.1 - 0.13 11.8 2.2 0.51 9.9 0.6 2.6 3 0 0 3 3 3 0 PQQ-like domain Rax2 PF12768.7 KXL41377.1 - 2.7e-65 219.9 4.0 3e-64 216.4 0.0 4.3 4 1 1 5 5 5 1 Cortical protein marker for cell polarity HCV_NS4a PF01006.20 KXL41377.1 - 0.079 12.7 0.2 0.079 12.7 0.2 4.2 5 0 0 5 5 5 0 Hepatitis C virus non-structural protein NS4a Kelch_4 PF13418.6 KXL41377.1 - 1.2 9.2 4.6 1.2 9.3 0.7 3.1 3 0 0 3 3 3 0 Galactose oxidase, central domain Pyrophosphatase PF00719.19 KXL41378.1 - 4.5e-58 195.6 0.1 5.9e-58 195.2 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Tmemb_14 PF03647.13 KXL41379.1 - 5.7e-25 87.9 7.8 7.2e-25 87.6 7.8 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C DAD PF02109.16 KXL41380.1 - 4.8e-51 171.7 2.1 5.4e-51 171.5 2.1 1.0 1 0 0 1 1 1 1 DAD family RTC PF01137.21 KXL41381.1 - 1.8e-28 99.3 0.1 2.1e-28 99.0 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KXL41381.1 - 5.6e-27 94.3 0.0 9.6e-27 93.5 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RRM_1 PF00076.22 KXL41382.1 - 3.2e-21 74.9 0.0 4e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXL41382.1 - 0.00087 19.4 0.0 0.0014 18.7 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif GRP PF07172.11 KXL41382.1 - 0.0075 16.9 18.5 0.011 16.4 18.5 1.3 1 0 0 1 1 1 1 Glycine rich protein family PAP_PilO PF06864.12 KXL41382.1 - 0.089 11.6 0.1 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) RRM_occluded PF16842.5 KXL41382.1 - 0.1 12.4 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Rtt106_N PF18215.1 KXL41384.1 - 0.0084 15.8 0.0 0.017 14.8 0.0 1.5 1 1 0 1 1 1 1 Histone chaperone Rtt106 N-terminal domain HATPase_c_3 PF13589.6 KXL41385.1 - 2.5e-14 53.3 0.0 7.5e-14 51.7 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 KXL41385.1 - 2.4e-05 24.1 1.3 0.00067 19.5 0.5 2.9 2 1 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 KXL41385.1 - 0.0016 18.9 0.0 0.0047 17.4 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Alpha-E PF04168.12 KXL41386.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.5 1 1 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. Septin PF00735.18 KXL41387.1 - 2.6e-114 381.2 0.7 3.2e-114 381.0 0.7 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KXL41387.1 - 2.2e-08 34.2 0.0 4.6e-08 33.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXL41387.1 - 1.5e-06 27.9 0.2 0.0035 16.9 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KXL41387.1 - 1.5e-05 24.4 0.0 2.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KXL41387.1 - 1.6e-05 24.9 0.6 0.00014 21.8 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KXL41387.1 - 0.00028 21.0 0.3 0.37 10.8 0.2 2.6 1 1 1 2 2 2 2 Dynamin family AAA_7 PF12775.7 KXL41387.1 - 0.00088 18.8 0.1 0.005 16.4 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region NB-ARC PF00931.22 KXL41387.1 - 0.001 18.3 0.1 0.0017 17.6 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KXL41387.1 - 0.0095 16.3 0.0 0.023 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXL41387.1 - 0.015 15.6 0.0 0.029 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 KXL41387.1 - 0.016 14.6 0.1 0.38 10.1 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Roc PF08477.13 KXL41387.1 - 0.018 15.3 0.0 0.038 14.2 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 KXL41387.1 - 0.019 15.5 1.3 0.033 14.7 1.2 1.8 1 1 0 1 1 1 0 ABC transporter G-alpha PF00503.20 KXL41387.1 - 0.034 13.3 0.9 0.092 11.9 0.9 1.9 1 1 0 1 1 1 0 G-protein alpha subunit FtsK_SpoIIIE PF01580.18 KXL41387.1 - 0.059 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Microtub_bd PF16796.5 KXL41387.1 - 0.087 12.8 0.6 0.54 10.2 0.0 2.2 2 0 0 2 2 2 0 Microtubule binding AAA_29 PF13555.6 KXL41387.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain WD40 PF00400.32 KXL41388.1 - 5.4e-18 65.0 6.3 1.1e-06 29.2 0.6 6.8 7 1 0 7 7 7 5 WD domain, G-beta repeat Ribosomal_L32p PF01783.23 KXL41388.1 - 3.1e-13 49.7 7.2 8.7e-13 48.3 7.2 1.8 1 0 0 1 1 1 1 Ribosomal L32p protein family ANAPC4_WD40 PF12894.7 KXL41388.1 - 2e-12 47.3 2.1 0.0016 18.7 0.7 4.5 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain zf-AN1 PF01428.16 KXL41388.1 - 0.089 13.0 1.7 0.23 11.6 1.7 1.8 1 0 0 1 1 1 0 AN1-like Zinc finger zf-ribbon_3 PF13248.6 KXL41388.1 - 0.11 12.0 1.6 0.22 11.0 1.6 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Acyl_transf_3 PF01757.22 KXL41390.1 - 2e-33 115.9 43.4 2.7e-33 115.5 43.4 1.1 1 0 0 1 1 1 1 Acyltransferase family Gly_transf_sug PF04488.15 KXL41391.1 - 4e-11 43.4 0.1 7.5e-11 42.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF3712 PF12505.8 KXL41392.1 - 7.7e-23 81.1 0.5 2.1e-22 79.7 0.5 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) TMEM108 PF15759.5 KXL41392.1 - 0.032 13.3 0.6 0.046 12.7 0.6 1.1 1 0 0 1 1 1 0 TMEM108 family VSP PF03302.13 KXL41393.1 - 7.7e-05 21.7 1.4 7.7e-05 21.7 1.4 1.8 2 0 0 2 2 2 1 Giardia variant-specific surface protein Podoplanin PF05808.11 KXL41393.1 - 0.002 18.3 1.2 0.0029 17.7 0.1 1.9 2 0 0 2 2 2 1 Podoplanin DUF5518 PF17647.1 KXL41393.1 - 0.0039 17.3 0.1 0.0086 16.2 0.1 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5518) Ecm33 PF12454.8 KXL41393.1 - 0.015 15.5 1.7 0.037 14.2 1.7 1.7 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Recep_L_domain PF01030.24 KXL41393.1 - 0.015 15.4 5.8 3.8 7.7 1.9 3.7 2 1 1 3 3 3 0 Receptor L domain G6B PF15096.6 KXL41393.1 - 0.021 14.6 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 G6B family SKG6 PF08693.10 KXL41393.1 - 0.034 13.6 4.0 0.072 12.5 4.0 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2613 PF11021.8 KXL41393.1 - 0.041 14.0 0.5 0.22 11.7 0.5 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) DUF4690 PF15756.5 KXL41393.1 - 0.14 12.7 2.0 0.41 11.3 1.3 2.2 1 1 0 1 1 1 0 Small Novel Rich in Cartilage 2OG-FeII_Oxy PF03171.20 KXL41394.1 - 8.4e-12 45.5 0.0 1.8e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KXL41394.1 - 3.1e-09 37.6 0.0 5.4e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal ILVD_EDD PF00920.21 KXL41395.1 - 2.3e-155 518.1 0.0 2.6e-155 518.0 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family RNA_Me_trans PF04252.13 KXL41396.1 - 3.8e-75 251.9 0.0 4.3e-75 251.7 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Endosulfine PF04667.17 KXL41397.1 - 8.6e-31 105.9 0.8 1.4e-30 105.2 0.8 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Aconitase PF00330.20 KXL41398.1 - 1e-140 469.9 0.0 1.2e-140 469.6 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KXL41398.1 - 5.6e-39 133.5 0.0 8.7e-39 132.9 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain 4HBT PF03061.22 KXL41399.1 - 0.019 15.3 0.8 1.8 9.0 0.0 2.7 3 0 0 3 3 3 0 Thioesterase superfamily MHYT PF03707.16 KXL41402.1 - 7.4e-17 61.3 15.7 2e-08 34.3 0.1 5.1 4 1 0 4 4 4 3 Bacterial signalling protein N terminal repeat DUF4064 PF13273.6 KXL41402.1 - 0.97 9.7 5.5 9.7 6.5 1.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Peptidase_U4 PF03419.13 KXL41402.1 - 1.9 7.7 6.9 3 7.1 6.3 1.6 1 1 0 1 1 1 0 Sporulation factor SpoIIGA Peptidase_A8 PF01252.18 KXL41402.1 - 3.6 7.8 9.4 10 6.3 6.8 2.7 1 1 1 2 2 2 0 Signal peptidase (SPase) II FAD_binding_3 PF01494.19 KXL41403.1 - 1.8e-16 60.4 0.0 3.6e-16 59.3 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXL41403.1 - 0.00016 21.3 0.6 0.025 14.2 0.4 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXL41403.1 - 0.015 15.9 0.1 0.039 14.5 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXL41403.1 - 0.038 14.2 0.1 0.086 13.1 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXL41403.1 - 0.098 11.9 0.1 0.29 10.3 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase WD40 PF00400.32 KXL41404.1 - 1.4e-14 54.2 9.8 0.00097 19.9 0.1 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL41404.1 - 1.1e-06 28.8 0.0 0.021 15.1 0.0 4.9 2 2 5 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXL41404.1 - 0.00091 18.3 0.0 0.0069 15.4 0.0 2.1 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KXL41404.1 - 0.002 16.9 0.2 0.25 9.9 0.1 2.8 2 1 0 3 3 3 1 Nucleoporin Nup120/160 Mur_ligase_M PF08245.12 KXL41406.1 - 9.4e-05 22.5 0.0 0.051 13.6 0.0 2.4 2 0 0 2 2 2 2 Mur ligase middle domain Mur_ligase_C PF02875.21 KXL41406.1 - 0.002 18.4 0.0 0.0045 17.2 0.0 1.6 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain DENN PF02141.21 KXL41407.1 - 5.4e-55 186.2 0.1 9.7e-55 185.4 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KXL41407.1 - 2.2e-15 57.1 0.1 5.7e-15 55.8 0.1 1.8 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 KXL41407.1 - 6.4e-14 51.7 1.4 1.7e-13 50.3 1.4 1.8 1 0 0 1 1 1 1 dDENN domain C1_1 PF00130.22 KXL41407.1 - 2.2e-06 27.5 7.5 3.5e-06 26.8 7.5 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KXL41407.1 - 2.4e-05 24.5 4.7 4.9e-05 23.5 4.7 1.5 1 0 0 1 1 1 1 C1 domain PHD PF00628.29 KXL41407.1 - 0.0012 18.7 4.0 0.0023 17.8 4.0 1.4 1 0 0 1 1 1 1 PHD-finger SPA PF08616.10 KXL41407.1 - 0.037 14.0 0.0 0.075 13.0 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis Vps39_2 PF10367.9 KXL41407.1 - 0.72 10.3 2.1 1.5 9.3 2.1 1.5 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Prok-RING_1 PF14446.6 KXL41407.1 - 0.8 9.7 5.2 1.5 8.8 5.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Zf_RING PF16744.5 KXL41407.1 - 0.96 9.6 3.5 2 8.6 3.5 1.4 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING_2 PF13639.6 KXL41407.1 - 1.2 9.5 6.6 2.3 8.6 6.6 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 KXL41407.1 - 3.4 7.7 7.4 6.4 6.8 7.4 1.4 1 0 0 1 1 1 0 zinc-RING finger domain DUF974 PF06159.13 KXL41408.1 - 1.8e-73 247.4 0.0 2.2e-73 247.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) DUF5067 PF16729.5 KXL41408.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5067) SET PF00856.28 KXL41409.1 - 5.5e-12 46.4 0.0 1.2e-10 42.0 0.0 2.1 1 1 0 1 1 1 1 SET domain DUF2408 PF10303.9 KXL41410.1 - 4.1e-47 160.1 16.1 2.7e-31 108.9 3.5 5.5 3 3 2 5 5 5 4 Protein of unknown function (DUF2408) APC_N_CC PF16689.5 KXL41410.1 - 0.069 13.2 0.4 0.38 10.9 0.4 2.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain DUF3368 PF11848.8 KXL41410.1 - 0.09 12.6 0.0 1.3 8.8 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3368) Caprin-1_dimer PF18293.1 KXL41410.1 - 0.14 12.6 3.7 1.4 9.4 0.0 3.7 4 1 0 4 4 3 0 Caprin-1 dimerization domain ACP_PD PF04336.12 KXL41410.1 - 0.17 12.4 2.0 1.7 9.1 0.4 3.1 2 1 0 2 2 2 0 Acyl carrier protein phosphodiesterase MAP65_ASE1 PF03999.12 KXL41410.1 - 0.18 10.5 8.7 0.36 9.5 8.7 1.5 1 1 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Spore_III_AB PF09548.10 KXL41410.1 - 0.19 11.8 2.3 0.34 11.0 0.2 2.5 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) DUF4349 PF14257.6 KXL41410.1 - 0.23 10.9 1.9 0.95 8.9 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4349) Cob_adeno_trans PF01923.18 KXL41410.1 - 0.31 11.2 4.5 16 5.6 0.1 3.4 2 2 1 3 3 3 0 Cobalamin adenosyltransferase Snapin_Pallidin PF14712.6 KXL41410.1 - 0.4 11.1 12.0 1.4 9.4 2.1 4.3 4 1 0 4 4 4 0 Snapin/Pallidin ATG16 PF08614.11 KXL41410.1 - 0.46 10.7 13.4 3.8 7.7 0.2 3.7 4 1 0 4 4 4 0 Autophagy protein 16 (ATG16) Use1 PF09753.9 KXL41410.1 - 1.3 8.6 9.1 0.88 9.2 2.3 2.6 1 1 0 2 2 2 0 Membrane fusion protein Use1 CLZ PF16526.5 KXL41410.1 - 2.2 8.7 6.3 10 6.5 0.2 3.4 2 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TMF_TATA_bd PF12325.8 KXL41410.1 - 6.9 6.9 11.6 0.35 11.1 2.4 3.4 4 1 0 4 4 4 0 TATA element modulatory factor 1 TATA binding Ribosomal_60s PF00428.19 KXL41411.1 - 2.2e-26 92.3 9.0 2.7e-26 92.0 9.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cytomega_UL84 PF06284.11 KXL41411.1 - 0.23 9.9 0.6 0.26 9.7 0.6 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein SOG2 PF10428.9 KXL41412.1 - 1.1e-29 104.1 10.1 6.2e-20 71.9 4.1 3.1 2 1 1 3 3 3 2 RAM signalling pathway protein LRR_8 PF13855.6 KXL41412.1 - 4e-14 52.1 4.8 2.2e-07 30.5 0.5 3.3 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KXL41412.1 - 6.2e-10 39.2 5.0 8e-05 22.9 0.3 4.4 3 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXL41412.1 - 0.001 19.3 1.2 8.6 7.3 0.1 4.5 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 KXL41412.1 - 0.0072 16.3 1.8 15 6.0 0.1 4.4 4 0 0 4 4 4 2 Leucine Rich repeat LRR_9 PF14580.6 KXL41412.1 - 0.032 13.7 0.2 0.073 12.6 0.2 1.5 1 0 0 1 1 1 0 Leucine-rich repeat BPL_LplA_LipB PF03099.19 KXL41413.1 - 3.7e-05 23.6 0.0 7.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family SGL PF08450.12 KXL41414.1 - 3e-24 85.9 0.0 4.4e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 KXL41414.1 - 0.0016 18.4 0.2 1 9.5 0.0 3.7 3 0 0 3 3 3 1 NHL repeat Str_synth PF03088.16 KXL41414.1 - 0.01 15.9 0.0 0.055 13.6 0.0 2.2 2 0 0 2 2 2 0 Strictosidine synthase PQQ_3 PF13570.6 KXL41414.1 - 0.11 13.1 1.2 19 5.9 0.1 3.1 3 0 0 3 3 3 0 PQQ-like domain DUF5050 PF16472.5 KXL41414.1 - 0.14 11.4 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5050) Tyrosinase PF00264.20 KXL41415.1 - 3.8e-51 174.5 2.8 7.3e-51 173.6 2.8 1.5 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KXL41415.1 - 1.6e-28 99.8 0.0 2.9e-28 99.0 0.0 1.5 1 0 0 1 1 1 1 Tyosinase C-terminal domain UPF0160 PF03690.13 KXL41416.1 - 1.9e-121 405.6 0.0 2.1e-121 405.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) ICE2 PF08426.10 KXL41417.1 - 2.4e-135 451.8 0.0 2.7e-135 451.6 0.0 1.0 1 0 0 1 1 1 1 ICE2 PRIMA1 PF16101.5 KXL41417.1 - 0.047 13.7 1.2 0.09 12.8 0.2 1.9 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 adh_short_C2 PF13561.6 KXL41418.1 - 3.2e-35 121.8 0.0 9.4e-21 74.4 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL41418.1 - 8.6e-32 110.2 0.0 1.1e-30 106.5 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL41418.1 - 2.1e-08 34.3 0.4 3.5e-07 30.3 0.0 2.3 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXL41418.1 - 0.0075 15.8 0.0 0.014 14.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXL41418.1 - 0.026 13.9 0.0 0.06 12.7 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DUF1776 PF08643.10 KXL41418.1 - 0.048 13.0 0.1 0.094 12.1 0.1 1.5 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.26 KXL41418.1 - 0.069 13.1 0.4 0.15 12.1 0.4 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pyr_redox PF00070.27 KXL41418.1 - 0.11 13.1 0.5 0.45 11.1 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 KXL41419.1 - 6.9e-71 238.7 0.0 1.1e-70 238.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL41419.1 - 2.3e-49 168.0 0.0 3.7e-49 167.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXL41419.1 - 0.0013 17.6 0.0 0.0023 16.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase GerD PF17898.1 KXL41419.1 - 0.028 14.4 0.3 0.11 12.4 0.4 1.9 2 0 0 2 2 2 0 Spore germination GerD central core domain KAP PF05804.12 KXL41419.1 - 0.041 12.1 0.4 0.064 11.4 0.4 1.2 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 KXL41419.1 - 0.091 12.0 0.2 18 4.5 0.1 2.7 2 1 0 2 2 2 0 V-ATPase subunit H Kinase-like PF14531.6 KXL41419.1 - 0.17 11.2 0.0 0.75 9.1 0.0 1.9 2 0 0 2 2 2 0 Kinase-like FTA2 PF13095.6 KXL41419.1 - 0.17 11.5 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Crr6 PF08847.11 KXL41420.1 - 0.064 12.9 0.0 0.093 12.4 0.0 1.2 1 0 0 1 1 1 0 Chlororespiratory reduction 6 Guanylate_kin PF00625.21 KXL41422.1 - 1.1e-65 220.7 0.0 1.3e-65 220.6 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 KXL41422.1 - 9.5e-07 29.4 0.1 2.9e-06 27.8 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KXL41422.1 - 3e-05 24.2 0.0 0.00034 20.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXL41422.1 - 7e-05 23.4 0.0 0.00017 22.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXL41422.1 - 9.9e-05 22.6 0.0 0.0002 21.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KXL41422.1 - 0.00038 20.7 0.0 0.017 15.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KXL41422.1 - 0.00038 21.0 0.0 0.00062 20.3 0.0 1.7 1 1 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 KXL41422.1 - 0.00049 20.2 0.0 0.0022 18.1 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXL41422.1 - 0.0013 18.7 0.0 0.0027 17.6 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase RNA_helicase PF00910.22 KXL41422.1 - 0.0024 18.2 0.0 0.0038 17.6 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_17 PF13207.6 KXL41422.1 - 0.0033 17.8 0.2 0.54 10.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain dNK PF01712.19 KXL41422.1 - 0.0074 16.2 0.0 0.13 12.1 0.0 2.2 2 0 0 2 2 2 1 Deoxynucleoside kinase NACHT PF05729.12 KXL41422.1 - 0.0083 16.0 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.6 KXL41422.1 - 0.01 15.8 0.0 0.021 14.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXL41422.1 - 0.011 15.4 0.1 0.026 14.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 KXL41422.1 - 0.016 14.8 0.0 0.057 13.0 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 KXL41422.1 - 0.017 15.0 0.1 0.036 14.0 0.1 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KXL41422.1 - 0.027 14.2 0.2 0.14 11.9 0.0 2.1 1 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KXL41422.1 - 0.029 13.6 0.0 0.072 12.3 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 KXL41422.1 - 0.04 14.4 0.1 0.64 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KXL41422.1 - 0.046 12.8 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 KXL41422.1 - 0.051 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 KXL41422.1 - 0.058 13.1 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KXL41422.1 - 0.062 13.0 0.0 0.093 12.5 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 KXL41422.1 - 0.068 13.1 0.0 0.098 12.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain NTPase_1 PF03266.15 KXL41422.1 - 0.097 12.6 0.0 0.15 12.0 0.0 1.4 1 1 0 1 1 1 0 NTPase AAA_7 PF12775.7 KXL41422.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ADK PF00406.22 KXL41422.1 - 0.11 12.6 0.3 3.5 7.7 0.1 2.5 2 1 1 3 3 3 0 Adenylate kinase AAA PF00004.29 KXL41422.1 - 0.11 12.9 0.2 0.45 11.0 0.2 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.17 KXL41422.1 - 0.12 12.0 0.2 12 5.6 0.0 2.5 1 1 2 3 3 3 0 Thymidylate kinase Adeno_IVa2 PF02456.15 KXL41422.1 - 0.14 10.9 0.0 0.26 10.0 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein PP2C PF00481.21 KXL41424.1 - 9e-81 271.3 0.0 1.1e-80 271.0 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C LpxD PF04613.14 KXL41424.1 - 0.15 11.8 0.0 0.44 10.4 0.0 1.7 1 0 0 1 1 1 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD CDC45 PF02724.14 KXL41425.1 - 1.1 7.5 6.7 1.1 7.4 6.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Lin-8 PF03353.15 KXL41425.1 - 2.9 7.4 7.9 3.3 7.2 7.9 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CTP_transf_like PF01467.26 KXL41426.1 - 4e-31 108.1 0.0 6.4e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 KXL41426.1 - 0.036 14.0 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 FAD synthetase Tcp11 PF05794.13 KXL41427.1 - 1.7e-90 304.3 0.5 2.3e-90 303.8 0.5 1.1 1 0 0 1 1 1 1 T-complex protein 11 TPR_10 PF13374.6 KXL41430.1 - 3.3e-08 33.1 2.0 0.0001 22.0 0.1 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXL41430.1 - 4.9e-05 23.5 4.7 0.034 14.4 1.9 4.5 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXL41430.1 - 0.0025 17.8 6.3 9.6 6.6 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat Viral_Hsp90 PF03225.14 KXL41430.1 - 0.18 10.3 0.6 0.32 9.4 0.6 1.3 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue TPR_4 PF07721.14 KXL41430.1 - 4.5 8.2 7.8 3.4 8.6 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat AhpC-TSA PF00578.21 KXL41432.1 - 1.2e-30 105.9 0.0 1.7e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXL41432.1 - 3.5e-13 49.5 0.0 4.6e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KXL41432.1 - 2.6e-10 40.0 0.0 5.1e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin MFS_1 PF07690.16 KXL41433.1 - 6.9e-42 143.6 28.4 6.9e-42 143.6 28.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL41433.1 - 2.2e-10 40.0 9.3 2.2e-10 40.0 9.3 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXL41433.1 - 3.9e-10 38.8 3.6 5.6e-10 38.3 3.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) LtrA PF06772.11 KXL41434.1 - 3.1e-44 151.7 34.5 3.7e-44 151.4 34.5 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) GAS PF13851.6 KXL41434.1 - 0.21 10.9 0.1 0.3 10.4 0.1 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Vps5 PF09325.10 KXL41435.1 - 1.6e-82 276.6 0.3 2.3e-82 276.1 0.3 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KXL41435.1 - 2.1e-25 88.9 0.0 4.8e-25 87.7 0.0 1.6 1 0 0 1 1 1 1 PX domain KELK PF15796.5 KXL41435.1 - 0.0046 17.4 3.1 0.017 15.6 1.6 2.5 2 0 0 2 2 2 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase Sec34 PF04136.15 KXL41435.1 - 0.066 13.1 0.1 6 6.7 0.0 2.4 2 0 0 2 2 2 0 Sec34-like family BAR_3_WASP_bdg PF10456.9 KXL41435.1 - 0.087 12.3 0.3 1.8 7.9 0.0 2.4 1 1 2 3 3 3 0 WASP-binding domain of Sorting nexin protein FadA PF09403.10 KXL41435.1 - 0.21 12.1 2.2 0.5 10.9 0.1 2.7 2 0 0 2 2 2 0 Adhesion protein FadA TFIIA PF03153.13 KXL41435.1 - 1.2 9.1 15.1 0.58 10.1 0.1 3.0 2 1 1 3 3 3 0 Transcription factor IIA, alpha/beta subunit Snapin_Pallidin PF14712.6 KXL41435.1 - 2.2 8.8 6.0 20 5.7 0.7 2.7 3 0 0 3 3 3 0 Snapin/Pallidin DUF5315 PF17242.2 KXL41435.1 - 3.4 7.6 7.3 1.4 8.8 2.1 2.4 2 0 0 2 2 2 0 Disordered region of unknown function (DUF5315) F-box-like PF12937.7 KXL41436.1 - 4.9 7.1 10.9 1.4 8.9 0.4 3.3 4 0 0 4 4 4 0 F-box-like S1 PF00575.23 KXL41438.1 - 5.9e-75 247.6 28.4 3.2e-16 59.4 0.8 12.4 12 0 0 12 12 12 10 S1 RNA binding domain Suf PF05843.14 KXL41438.1 - 1.8e-10 41.3 10.5 0.0045 17.0 0.0 4.1 3 1 1 4 4 4 3 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KXL41438.1 - 5.3e-08 33.0 2.3 0.58 11.1 0.1 5.6 1 1 4 5 5 5 3 Tetratricopeptide repeat RNase_II_C_S1 PF18614.1 KXL41438.1 - 8.4e-05 22.4 7.5 1.4 8.9 0.0 6.5 7 0 0 7 7 7 2 RNase II-type exonuclease C-terminal S1 domain TPR_19 PF14559.6 KXL41438.1 - 0.0001 22.8 0.0 1.3 9.6 0.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXL41438.1 - 0.0037 17.8 0.1 7.8 7.4 0.0 4.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXL41438.1 - 0.0073 16.4 0.1 0.054 13.7 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXL41438.1 - 0.017 15.4 0.2 14 6.0 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.9 KXL41438.1 - 0.033 13.9 0.2 0.24 11.1 0.2 2.1 1 1 0 1 1 1 0 26S proteasome subunit RPN7 Staphopain_pro PF14731.6 KXL41438.1 - 0.049 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Staphopain proregion Pep_M12B_propep PF01562.19 KXL41438.1 - 0.083 13.1 0.1 0.42 10.8 0.0 2.3 2 1 1 3 3 2 0 Reprolysin family propeptide TPR_7 PF13176.6 KXL41438.1 - 0.16 12.1 0.3 3.2 8.0 0.0 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat RNA_pol_Rbc25 PF08292.12 KXL41438.1 - 5.5 7.2 5.8 33 4.7 0.0 4.9 5 0 0 5 5 5 0 RNA polymerase III subunit Rpc25 ProQ_C PF17516.2 KXL41438.1 - 9.6 5.7 8.1 8.1 6.0 0.0 4.4 5 0 0 5 5 5 0 ProQ C-terminal domain adh_short PF00106.25 KXL41439.1 - 2.9e-29 101.9 0.0 4.7e-29 101.2 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL41439.1 - 2.3e-25 89.6 0.0 3.3e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL41439.1 - 9e-06 25.7 0.1 0.00021 21.2 0.0 2.1 2 0 0 2 2 2 1 KR domain DsbC_N PF10411.9 KXL41439.1 - 0.15 11.6 0.2 2.5 7.6 0.0 2.6 3 0 0 3 3 3 0 Disulfide bond isomerase protein N-terminus GCV_T PF01571.21 KXL41440.1 - 5.3e-05 22.7 0.0 8.3e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DnaJ PF00226.31 KXL41441.1 - 4e-19 68.5 0.1 1.9e-18 66.4 0.0 2.2 2 0 0 2 2 2 1 DnaJ domain RRM_1 PF00076.22 KXL41441.1 - 0.00034 20.4 0.0 0.0014 18.4 0.1 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 KXL41441.1 - 0.042 13.7 0.5 0.18 11.6 0.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4523) DCP2 PF05026.13 KXL41442.1 - 1.5e-26 92.6 0.1 7.7e-26 90.2 0.0 2.1 2 0 0 2 2 2 1 Dcp2, box A domain NUDIX PF00293.28 KXL41442.1 - 1.7e-17 63.7 0.0 3.1e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain adh_short_C2 PF13561.6 KXL41443.1 - 2.5e-49 167.9 2.9 4e-49 167.3 2.9 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL41443.1 - 8.6e-49 165.7 0.9 1e-48 165.4 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL41443.1 - 3.3e-11 43.4 0.7 9.3e-11 42.0 0.4 1.9 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 KXL41443.1 - 0.0023 17.5 0.4 0.0062 16.0 0.4 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KXL41443.1 - 0.098 12.0 0.1 0.3 10.4 0.1 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DASH_Ask1 PF08655.10 KXL41444.1 - 9.2e-30 102.3 0.1 1.4e-29 101.8 0.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 Nop14 PF04147.12 KXL41444.1 - 0.17 10.1 5.1 0.28 9.4 5.1 1.4 1 0 0 1 1 1 0 Nop14-like family Palm_thioest PF02089.15 KXL41445.1 - 9.1e-71 238.5 0.0 1.1e-70 238.3 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 KXL41445.1 - 0.01 16.5 0.9 0.015 15.9 0.9 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family OTT_1508_deam PF14441.6 KXL41449.1 - 9.3e-19 67.2 2.8 2.2e-18 66.0 2.8 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase Iso_dh PF00180.20 KXL41450.1 - 6.6e-90 301.8 0.0 7.9e-90 301.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF4875 PF16175.5 KXL41450.1 - 0.059 13.5 0.0 0.21 11.7 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4875) RIC3 PF15361.6 KXL41451.1 - 0.11 12.9 0.3 0.3 11.5 0.0 1.9 2 1 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Fungal_trans PF04082.18 KXL41452.1 - 5.4e-15 55.2 2.9 7.3e-14 51.4 2.9 2.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain 2-Hacid_dh_C PF02826.19 KXL41453.1 - 5e-58 195.4 0.1 7.2e-58 194.9 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXL41453.1 - 7.9e-20 70.9 0.0 9e-20 70.7 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXL41453.1 - 9.2e-05 22.7 0.0 0.00015 22.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 KXL41453.1 - 0.0039 17.3 0.0 0.0084 16.2 0.0 1.5 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 KXL41453.1 - 0.02 14.4 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain XdhC_C PF13478.6 KXL41453.1 - 0.099 13.1 0.0 0.23 12.0 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain Sugar_tr PF00083.24 KXL41454.1 - 5e-55 187.2 32.4 1.5e-32 113.0 5.1 2.7 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXL41454.1 - 6.4e-16 58.2 24.3 6.4e-16 58.2 24.3 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 KXL41454.1 - 0.93 10.1 4.9 0.24 12.0 0.5 2.3 2 1 0 2 2 2 0 Phage holin family 2 Sulfotransfer_4 PF17784.1 KXL41455.1 - 1.6e-66 224.2 0.0 1.8e-66 224.0 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXL41455.1 - 0.0007 20.0 0.0 0.27 11.6 0.0 2.3 1 1 1 2 2 2 2 Sulfotransferase family TPR_17 PF13431.6 KXL41456.1 - 0.008 16.5 0.2 2.5 8.7 0.0 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXL41456.1 - 1.7 9.7 10.3 3 8.9 0.8 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat Glucosamine_iso PF01182.20 KXL41457.1 - 6.8e-70 235.4 0.0 7.7e-70 235.3 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Abhydrolase_6 PF12697.7 KXL41458.1 - 5e-07 30.5 0.0 7.7e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXL41458.1 - 0.0014 18.3 0.0 0.0027 17.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Beta-lactamase PF00144.24 KXL41459.1 - 6.7e-42 143.9 0.2 2.3e-41 142.2 0.2 1.7 1 1 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 KXL41459.1 - 0.0043 16.7 0.0 0.012 15.2 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase enzyme family Peptidase_S11 PF00768.20 KXL41459.1 - 0.0047 16.4 0.1 0.0075 15.7 0.1 1.2 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase His_Phos_2 PF00328.22 KXL41460.1 - 2.5e-68 231.2 0.0 2.9e-68 231.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) NmrA PF05368.13 KXL41462.1 - 1.4e-12 47.6 0.0 9e-10 38.5 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 KXL41462.1 - 1.9e-09 37.7 0.0 5.2e-09 36.2 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KXL41462.1 - 0.079 12.4 0.1 0.32 10.4 0.0 2.0 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family AAA PF00004.29 KXL41463.1 - 1.4e-48 164.7 0.0 7.1e-42 143.0 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXL41463.1 - 3.9e-09 36.2 0.0 1.2e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain IstB_IS21 PF01695.17 KXL41463.1 - 5.7e-07 29.4 0.0 3.9e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.6 KXL41463.1 - 3.5e-06 27.5 0.1 5.5e-05 23.6 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 KXL41463.1 - 7.9e-06 26.1 0.0 2.4e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KXL41463.1 - 0.00092 19.2 0.0 0.0041 17.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KXL41463.1 - 0.0015 18.9 0.0 0.0044 17.4 0.0 1.8 1 0 0 1 1 1 1 RNA helicase Sigma54_activ_2 PF14532.6 KXL41463.1 - 0.0018 18.4 0.0 1.2 9.3 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 KXL41463.1 - 0.0023 18.2 0.1 0.034 14.4 0.1 2.7 1 1 0 1 1 1 1 AAA domain Bromodomain PF00439.25 KXL41463.1 - 0.0034 17.4 0.0 0.0091 16.0 0.0 1.7 1 0 0 1 1 1 1 Bromodomain AAA_33 PF13671.6 KXL41463.1 - 0.0049 17.0 1.6 0.042 14.0 0.0 3.3 4 0 0 4 4 3 1 AAA domain AAA_14 PF13173.6 KXL41463.1 - 0.0051 16.9 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KXL41463.1 - 0.0051 16.4 0.0 0.022 14.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KXL41463.1 - 0.01 16.4 0.0 0.09 13.3 0.0 2.7 3 0 0 3 3 1 0 AAA domain ABC_tran PF00005.27 KXL41463.1 - 0.014 15.9 0.1 0.075 13.6 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_30 PF13604.6 KXL41463.1 - 0.019 14.7 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KXL41463.1 - 0.02 14.1 0.0 0.032 13.4 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 KXL41463.1 - 0.026 13.9 0.0 0.076 12.4 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KXL41463.1 - 0.03 14.1 0.1 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 KXL41463.1 - 0.033 14.1 0.0 0.62 9.9 0.0 2.7 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 KXL41463.1 - 0.083 12.0 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 KXL41463.1 - 0.096 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 KXL41463.1 - 0.1 12.8 0.0 0.29 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KXL41463.1 - 0.17 11.7 0.0 0.42 10.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KXL41463.1 - 0.34 10.7 0.0 0.34 10.7 0.0 3.6 5 0 0 5 5 4 0 AAA domain DUF2550 PF10739.9 KXL41464.1 - 0.39 10.7 2.5 0.28 11.2 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2550) DUF2294 PF10057.9 KXL41465.1 - 0.031 14.4 0.0 0.033 14.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2294) DBP10CT PF08147.12 KXL41465.1 - 0.1 12.9 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 DBP10CT (NUC160) domain Mito_carr PF00153.27 KXL41466.1 - 6.1e-72 237.6 0.2 1.7e-24 85.5 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KXL41466.1 - 2.6e-07 31.0 0.9 1.4e-06 28.6 0.5 2.3 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KXL41466.1 - 6.9e-07 28.7 0.4 4.4e-06 26.2 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KXL41466.1 - 1.2e-05 24.5 1.8 3.1e-05 23.2 0.1 2.7 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 KXL41466.1 - 0.008 15.6 0.1 0.018 14.6 0.1 1.6 1 0 0 1 1 1 1 EF hand Serine_protease PF18405.1 KXL41466.1 - 0.06 12.5 0.1 14 4.8 0.0 2.9 3 0 0 3 3 3 0 Gammaproteobacterial serine protease AMP-binding PF00501.28 KXL41467.1 - 3.3e-52 177.5 0.0 4.7e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXL41467.1 - 0.0011 19.9 0.0 0.0048 17.8 0.0 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain tRNA-synt_1 PF00133.22 KXL41468.1 - 2.8e-137 458.5 0.0 5.6e-137 457.5 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KXL41468.1 - 9.1e-22 77.7 0.0 1.5e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KXL41468.1 - 7.4e-18 64.5 0.0 1.4e-09 37.2 0.0 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) Ferric_reduct PF01794.19 KXL41469.1 - 1.1e-16 61.1 19.1 1.3e-16 60.9 15.5 2.6 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KXL41469.1 - 1.3e-15 57.4 0.0 2.9e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KXL41469.1 - 7.7e-11 42.4 0.0 1.2e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Tudor_4 PF18358.1 KXL41470.1 - 0.061 12.9 0.0 0.89 9.2 0.0 2.2 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain GCP_C_terminal PF04130.13 KXL41471.1 - 1.9e-51 175.4 0.2 3e-51 174.7 0.2 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KXL41471.1 - 2.1e-06 27.6 0.4 4.4e-06 26.5 0.4 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal SNF2_N PF00176.23 KXL41472.1 - 7.9e-63 212.3 0.0 7.9e-63 212.3 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXL41472.1 - 8.2e-22 77.7 0.1 4.7e-20 72.0 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL41472.1 - 1.6e-06 28.2 0.0 7e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KXL41472.1 - 0.0012 18.1 2.8 0.72 9.0 0.0 3.5 3 1 0 3 3 3 2 Class II histone deacetylase complex subunits 2 and 3 XisH PF08814.10 KXL41472.1 - 0.069 13.3 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 XisH protein MobB PF03205.14 KXL41472.1 - 0.072 13.0 0.2 1.7 8.5 0.0 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Cytochrome_C554 PF13435.6 KXL41473.1 - 0.032 15.1 0.3 0.065 14.2 0.3 1.5 1 0 0 1 1 1 0 Cytochrome c554 and c-prime p450 PF00067.22 KXL41474.1 - 2.3e-59 201.4 0.0 3.2e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_N PF08240.12 KXL41475.1 - 1.8e-33 114.6 0.3 3.3e-33 113.8 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXL41475.1 - 2.2e-23 82.6 0.8 4e-23 81.8 0.8 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXL41475.1 - 7.9e-09 36.7 0.2 2.2e-08 35.2 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF4911 PF16256.5 KXL41475.1 - 0.0057 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4911) MTS PF05175.14 KXL41475.1 - 0.0069 16.0 0.1 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TrkA_N PF02254.18 KXL41475.1 - 0.028 14.7 0.2 0.071 13.4 0.2 1.7 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_31 PF13847.6 KXL41475.1 - 0.038 13.8 0.2 0.068 13.0 0.2 1.4 1 0 0 1 1 1 0 Methyltransferase domain DMAP1 PF05499.12 KXL41475.1 - 0.23 11.4 0.0 0.46 10.4 0.0 1.4 1 0 0 1 1 1 0 DNA methyltransferase 1-associated protein 1 (DMAP1) Yip1 PF04893.17 KXL41476.1 - 4.4e-14 52.6 13.5 5.9e-14 52.2 13.5 1.2 1 0 0 1 1 1 1 Yip1 domain GTP_EFTU PF00009.27 KXL41477.1 - 5.3e-34 117.5 0.1 4.2e-33 114.5 0.0 2.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KXL41477.1 - 3.8e-20 72.0 0.1 1e-19 70.6 0.1 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 KXL41477.1 - 3.5e-11 43.3 4.4 3.8e-09 36.8 0.2 3.7 3 0 0 3 3 3 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 KXL41477.1 - 2.7e-09 36.8 0.9 1.5e-08 34.5 0.9 2.3 1 1 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 KXL41477.1 - 1.7e-05 24.8 0.0 1.7e-05 24.8 0.0 3.7 4 0 0 4 4 4 1 50S ribosome-binding GTPase Roc PF08477.13 KXL41477.1 - 0.0014 18.9 0.0 0.0044 17.2 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KXL41477.1 - 0.018 14.8 0.0 0.018 14.8 0.0 2.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein SUR7 PF06687.12 KXL41479.1 - 4e-15 56.0 4.9 5.6e-15 55.5 4.9 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF4282 PF14110.6 KXL41479.1 - 0.017 15.9 10.1 0.017 15.9 10.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4282) DUF1286 PF06939.11 KXL41479.1 - 0.68 10.2 7.8 2.7 8.3 0.0 3.6 2 2 1 4 4 4 0 Protein of unknown function (DUF1286) Fig1 PF12351.8 KXL41479.1 - 1.3 8.9 18.6 3.1 7.7 16.7 2.2 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 E1-E2_ATPase PF00122.20 KXL41479.1 - 5.8 6.4 8.5 46 3.5 8.0 2.4 2 0 0 2 2 2 0 E1-E2 ATPase DUF5400 PF17379.2 KXL41480.1 - 1.1 9.8 8.5 0.067 13.7 3.3 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5400) Pyr_redox_2 PF07992.14 KXL41482.1 - 7.7e-33 114.0 0.1 9.8e-33 113.6 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXL41482.1 - 3.6e-12 46.7 0.0 1.8e-10 41.2 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXL41482.1 - 0.00026 20.3 0.0 0.00052 19.3 0.0 1.4 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXL41482.1 - 0.0011 18.3 0.1 0.0018 17.6 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXL41482.1 - 0.0022 18.0 1.0 12 5.9 0.0 3.9 3 1 1 4 4 4 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KXL41482.1 - 0.065 11.9 0.6 0.55 8.9 0.0 2.4 4 0 0 4 4 4 0 HI0933-like protein MtrB PF05440.12 KXL41483.1 - 0.16 12.4 0.0 0.38 11.2 0.0 1.7 1 1 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF2207 PF09972.9 KXL41483.1 - 0.33 9.7 1.4 0.5 9.1 0.9 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF948 PF06103.11 KXL41483.1 - 0.56 10.5 3.6 0.5 10.7 0.8 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) RNase_T PF00929.24 KXL41485.1 - 4.6e-08 33.8 0.0 3.6e-07 30.9 0.0 2.3 2 1 0 2 2 2 1 Exonuclease Myc_N PF01056.18 KXL41486.1 - 0.2 11.5 7.3 0.29 11.0 7.3 1.2 1 0 0 1 1 1 0 Myc amino-terminal region CENP-B_dimeris PF09026.10 KXL41486.1 - 0.2 12.0 3.0 0.52 10.7 3.0 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 KXL41486.1 - 0.64 9.3 3.2 0.93 8.7 3.2 1.3 1 0 0 1 1 1 0 NOA36 protein Tmemb_cc2 PF10267.9 KXL41486.1 - 1 8.4 3.3 1.3 8.0 3.3 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein FAM176 PF14851.6 KXL41486.1 - 1.2 8.8 4.6 0.59 9.8 1.7 2.0 1 1 0 1 1 1 0 FAM176 family SlyX PF04102.12 KXL41488.1 - 9e-06 26.2 2.7 0.017 15.7 0.0 2.9 2 1 0 2 2 2 2 SlyX BLOC1_2 PF10046.9 KXL41488.1 - 0.0017 18.6 0.3 1.6 9.1 0.0 2.1 2 0 0 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Csm1_N PF18504.1 KXL41488.1 - 0.002 18.4 2.0 0.62 10.4 0.2 2.5 2 1 1 3 3 3 2 Csm1 N-terminal domain FPP PF05911.11 KXL41488.1 - 0.0037 15.5 0.4 0.0043 15.3 0.4 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Filament PF00038.21 KXL41488.1 - 0.0067 16.0 0.9 0.015 14.9 0.7 1.6 1 1 0 1 1 1 1 Intermediate filament protein ZapB PF06005.12 KXL41488.1 - 0.0071 16.8 2.3 0.85 10.1 0.1 2.1 2 0 0 2 2 2 1 Cell division protein ZapB CC2-LZ PF16516.5 KXL41488.1 - 0.012 15.9 0.3 1.3 9.4 0.0 2.1 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator SPATA1_C PF15743.5 KXL41488.1 - 0.015 15.3 0.7 0.02 15.0 0.7 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus DUF1640 PF07798.11 KXL41488.1 - 0.017 15.2 0.2 0.024 14.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) NPV_P10 PF05531.12 KXL41488.1 - 0.021 15.3 0.7 3.1 8.3 0.2 2.3 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein PilO PF04350.13 KXL41488.1 - 0.045 13.9 0.9 9 6.4 0.1 2.1 2 0 0 2 2 2 0 Pilus assembly protein, PilO CENP-F_N PF10481.9 KXL41488.1 - 0.049 13.3 0.2 0.081 12.5 0.2 1.5 1 1 0 1 1 1 0 Cenp-F N-terminal domain FlaC_arch PF05377.11 KXL41488.1 - 0.051 14.0 1.2 0.39 11.1 0.1 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TMF_TATA_bd PF12325.8 KXL41488.1 - 0.074 13.3 2.0 0.16 12.2 2.0 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding KxDL PF10241.9 KXL41488.1 - 0.076 13.3 0.2 0.97 9.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein Tropomyosin_1 PF12718.7 KXL41488.1 - 0.095 12.8 2.4 0.31 11.2 2.4 1.7 1 1 0 1 1 1 0 Tropomyosin like DUF1664 PF07889.12 KXL41488.1 - 0.16 12.0 0.6 2.5 8.1 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.13 KXL41488.1 - 0.18 11.3 2.3 4.4 6.8 2.3 2.0 1 1 0 1 1 1 0 fzo-like conserved region Spc24 PF08286.11 KXL41488.1 - 0.19 12.0 2.8 2.1 8.6 0.6 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 MerR-DNA-bind PF09278.11 KXL41488.1 - 0.22 12.1 4.0 2.7 8.6 0.3 2.3 1 1 1 2 2 2 0 MerR, DNA binding MFS_1 PF07690.16 KXL41489.1 - 1.7e-35 122.6 31.3 1.2e-24 86.9 14.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL41489.1 - 8.3e-09 34.8 8.4 1.3e-08 34.2 8.4 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 KXL41489.1 - 1.8e-06 26.8 24.9 4.7e-05 22.1 1.8 3.2 2 2 1 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 KXL41489.1 - 2.2e-06 26.8 17.3 0.0027 16.6 8.6 2.3 1 1 1 2 2 2 2 MFS_1 like family OATP PF03137.20 KXL41489.1 - 0.00016 20.1 12.1 0.074 11.3 0.3 3.5 2 1 2 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family PEX11 PF05648.14 KXL41489.1 - 0.089 12.2 0.0 0.42 10.0 0.0 2.1 3 0 0 3 3 3 0 Peroxisomal biogenesis factor 11 (PEX11) FAM176 PF14851.6 KXL41489.1 - 0.45 10.2 4.2 2 8.0 0.0 2.6 3 0 0 3 3 3 0 FAM176 family PPR_2 PF13041.6 KXL41490.1 - 1.9e-23 82.4 5.0 3.8e-10 39.8 0.0 6.6 6 1 1 7 7 7 4 PPR repeat family PPR_3 PF13812.6 KXL41490.1 - 9e-11 41.7 0.1 9.4e-05 22.4 0.0 4.1 4 0 0 4 4 4 3 Pentatricopeptide repeat domain PPR PF01535.20 KXL41490.1 - 3.1e-09 36.5 7.6 9e-05 22.5 0.2 6.8 7 0 0 7 7 7 2 PPR repeat PPR_1 PF12854.7 KXL41490.1 - 5.3e-08 32.4 0.0 2.7e-05 23.8 0.0 4.1 5 0 0 5 5 5 1 PPR repeat PPR_long PF17177.4 KXL41490.1 - 0.0066 15.8 0.0 1.8 7.9 0.0 3.1 1 1 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP His_Phos_2 PF00328.22 KXL41491.1 - 4e-16 59.4 0.0 1.8e-14 53.9 0.0 2.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) TAF8_C PF10406.9 KXL41494.1 - 9.9e-13 48.4 0.3 2.1e-12 47.4 0.3 1.6 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 KXL41494.1 - 3.7e-08 33.3 0.0 6.2e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated FAM27 PF15832.5 KXL41494.1 - 0.005 17.3 0.1 0.012 16.2 0.1 1.6 1 0 0 1 1 1 1 FAM27 D and E protein family SUIM_assoc PF16619.5 KXL41494.1 - 0.46 10.6 3.9 17 5.5 0.1 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 K_channel_TID PF07941.11 KXL41495.1 - 0.00019 21.8 1.0 0.13 12.7 0.2 3.2 3 0 0 3 3 3 2 Potassium channel Kv1.4 tandem inactivation domain Pkinase PF00069.25 KXL41497.1 - 3.9e-74 249.4 0.0 5.1e-74 249.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL41497.1 - 4.5e-38 131.0 0.0 6.2e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 KXL41497.1 - 3.6e-20 72.6 0.0 3.5e-10 40.4 0.0 2.5 2 0 0 2 2 2 2 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 KXL41497.1 - 3.2e-17 62.4 0.2 5.8e-17 61.5 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 KXL41497.1 - 1.1e-05 24.9 0.0 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KXL41497.1 - 0.0018 17.3 0.1 0.003 16.6 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KXL41497.1 - 0.004 16.8 0.0 0.0072 15.9 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KXL41497.1 - 0.03 13.7 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.9 KXL41497.1 - 0.066 12.0 0.1 0.096 11.5 0.1 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 KXL41497.1 - 0.11 12.3 0.2 0.6 10.0 0.2 2.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family Inhibitor_I53 PF11714.8 KXL41497.1 - 1.2 9.3 6.8 10 6.4 0.1 3.3 3 0 0 3 3 3 0 Thrombin inhibitor Madanin G-alpha PF00503.20 KXL41498.1 - 2.1e-108 362.6 1.2 2.5e-108 362.4 1.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KXL41498.1 - 1.9e-14 53.5 3.4 1e-09 38.1 0.2 2.8 2 2 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KXL41498.1 - 3.2e-05 23.4 1.1 0.0019 17.6 0.2 2.6 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.18 KXL41498.1 - 0.037 13.4 0.0 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family GTP_EFTU PF00009.27 KXL41498.1 - 0.052 13.1 0.0 0.54 9.8 0.0 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Roc PF08477.13 KXL41498.1 - 0.062 13.5 0.1 6.9 6.9 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KXL41498.1 - 0.07 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DAP3 PF10236.9 KXL41498.1 - 0.09 11.9 0.4 0.17 11.0 0.4 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF2985 PF11204.8 KXL41498.1 - 0.16 12.2 0.0 0.5 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) LIM PF00412.22 KXL41501.1 - 2.9e-22 78.7 22.0 4.4e-13 49.2 4.8 3.0 3 0 0 3 3 3 2 LIM domain WRC PF08879.10 KXL41501.1 - 0.025 14.3 0.4 0.77 9.5 0.2 2.5 2 0 0 2 2 2 0 WRC zf-PARP PF00645.18 KXL41501.1 - 1.7 9.5 7.8 8.6 7.3 0.6 2.5 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Ribosomal_L5e PF17144.4 KXL41503.1 - 1.6e-80 268.9 0.3 3e-80 268.0 0.3 1.5 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KXL41503.1 - 9.8e-37 125.8 9.4 9.8e-37 125.8 9.4 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 KXL41503.1 - 0.013 15.8 1.6 0.015 15.7 0.1 1.8 2 0 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Thr_synth_N PF14821.6 KXL41503.1 - 0.11 12.7 0.2 4.1 7.7 0.0 2.8 3 0 0 3 3 3 0 Threonine synthase N terminus SET PF00856.28 KXL41504.1 - 8.3e-13 49.1 0.1 1.4e-11 45.1 0.0 2.5 2 1 0 2 2 2 1 SET domain MFS_1 PF07690.16 KXL41506.1 - 4.2e-31 108.2 22.8 5.3e-31 107.8 22.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXL41506.1 - 0.0082 14.6 2.0 0.012 14.1 2.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FPN1 PF06963.12 KXL41506.1 - 0.016 13.8 0.5 0.034 12.7 0.0 1.7 2 0 0 2 2 2 0 Ferroportin1 (FPN1) Zn_clus PF00172.18 KXL41507.1 - 5.8e-10 39.1 12.4 1.3e-09 38.0 12.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXL41507.1 - 6.7e-05 21.9 0.0 8.6e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_11 PF08241.12 KXL41508.1 - 1e-15 58.1 0.0 3.7e-15 56.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL41508.1 - 5e-15 56.0 0.0 1.1e-14 54.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL41508.1 - 1.3e-10 41.8 0.0 2.9e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL41508.1 - 2.1e-08 34.1 0.0 3.4e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXL41508.1 - 9.1e-07 28.9 0.0 1.4e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FF PF01846.19 KXL41509.1 - 1.3e-05 25.3 0.0 4.6e-05 23.5 0.0 2.0 1 0 0 1 1 1 1 FF domain AbLIM_anchor PF16182.5 KXL41509.1 - 0.11 12.3 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 Putative adherens-junction anchoring region of AbLIM Proteasome PF00227.26 KXL41510.1 - 2.6e-60 203.2 0.1 3.2e-60 202.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXL41510.1 - 3.6e-13 48.9 0.1 9.2e-13 47.6 0.1 1.8 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.14 KXL41510.1 - 0.0092 15.6 0.0 0.013 15.0 0.0 1.1 1 0 0 1 1 1 1 Nitrate reductase gamma subunit Pilin_PilX PF11530.8 KXL41510.1 - 0.025 14.5 0.0 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 Minor type IV pilin, PilX DUF5624 PF18538.1 KXL41510.1 - 0.038 14.1 0.5 0.097 12.8 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) Methyltransf_23 PF13489.6 KXL41511.1 - 6.4e-21 74.9 0.0 1e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL41511.1 - 2.4e-12 46.9 1.0 6.5e-05 22.8 0.4 2.9 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.6 KXL41511.1 - 6.5e-12 46.0 1.6 8.5e-09 36.0 0.5 3.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL41511.1 - 1.6e-08 35.0 0.5 6.4e-07 29.9 0.1 3.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL41511.1 - 1.4e-07 32.1 0.1 4.9e-05 24.0 0.1 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXL41511.1 - 0.00013 21.5 0.2 0.0013 18.2 0.0 2.5 3 0 0 3 3 3 1 Putative methyltransferase MTS PF05175.14 KXL41511.1 - 0.0014 18.2 0.0 0.0076 15.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KXL41511.1 - 0.0029 17.0 0.0 2 7.7 0.0 2.6 1 1 1 2 2 2 2 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KXL41511.1 - 0.13 12.4 0.0 0.34 11.0 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase DUF4854 PF16146.5 KXL41511.1 - 0.16 12.3 0.2 0.65 10.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4854) BTB PF00651.31 KXL41513.1 - 0.003 17.8 0.0 0.0052 17.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain PLDc_2 PF13091.6 KXL41514.1 - 2.1e-21 76.2 0.1 1.4e-14 54.1 0.0 2.4 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KXL41514.1 - 3.3e-05 23.9 0.6 0.0063 16.6 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.8 KXL41514.1 - 0.012 14.9 0.0 0.042 13.0 0.0 1.9 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB Ribosomal_S6e PF01092.19 KXL41515.1 - 2e-59 199.0 1.1 3.7e-59 198.2 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S6e Pribosyl_synth PF14572.6 KXL41516.1 - 7.2e-45 153.3 0.5 2.6e-38 131.9 0.5 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KXL41516.1 - 1.4e-43 147.5 0.2 5.1e-43 145.7 0.1 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KXL41516.1 - 2.5e-16 59.6 1.6 2.3e-15 56.4 0.8 2.1 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KXL41516.1 - 0.0014 18.1 0.1 0.0024 17.4 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase zf-HIT PF04438.16 KXL41517.1 - 1.3e-10 41.0 10.9 2e-10 40.3 10.9 1.3 1 0 0 1 1 1 1 HIT zinc finger YL1_C PF08265.11 KXL41517.1 - 0.0082 15.9 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain zf-MYND PF01753.18 KXL41517.1 - 0.0097 16.0 11.8 0.015 15.4 11.8 1.3 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KXL41517.1 - 0.39 11.1 9.0 0.71 10.2 9.0 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-C2H2_4 PF13894.6 KXL41517.1 - 7 7.8 10.4 0.48 11.4 3.9 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Sugar_tr PF00083.24 KXL41518.1 - 1.1e-85 288.2 20.6 1.4e-85 287.9 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL41518.1 - 2e-18 66.4 44.1 7.1e-18 64.6 21.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXL41518.1 - 2e-08 33.3 10.4 0.00035 19.2 2.3 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_4 PF06779.14 KXL41518.1 - 1.3e-05 24.7 1.6 2.9e-05 23.5 1.6 1.5 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 KXL41518.1 - 7.1e-05 21.8 5.1 7.1e-05 21.8 5.1 2.4 2 1 0 2 2 2 1 MFS_1 like family NAD_binding_1 PF00175.21 KXL41519.1 - 7.1e-14 52.4 0.0 1.5e-13 51.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 KXL41519.1 - 2.5e-12 47.3 0.1 8.5e-12 45.6 0.0 1.9 2 0 0 2 2 2 1 Globin NAD_binding_6 PF08030.12 KXL41519.1 - 2.9e-06 27.5 0.0 2.3e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 KXL41519.1 - 7.4e-06 26.3 0.0 1.2e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.8 KXL41519.1 - 2.2e-05 24.4 0.0 4.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Protoglobin PEP-utilisers_N PF05524.13 KXL41520.1 - 0.29 11.3 8.1 0.35 11.1 8.1 1.1 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal ATP-synt_B PF00430.18 KXL41520.1 - 2 8.5 18.1 2.2 8.4 18.1 1.0 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Med13_C PF06333.12 KXL41522.1 - 0.056 12.7 7.8 0.065 12.5 7.8 1.0 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Myc_N PF01056.18 KXL41522.1 - 0.078 12.9 0.4 0.086 12.7 0.4 1.0 1 0 0 1 1 1 0 Myc amino-terminal region NOA36 PF06524.12 KXL41522.1 - 0.36 10.1 2.1 0.36 10.1 2.1 1.1 1 0 0 1 1 1 0 NOA36 protein Neugrin PF06413.11 KXL41522.1 - 0.69 9.9 3.3 0.81 9.7 3.3 1.1 1 0 0 1 1 1 0 Neugrin Dehydrin PF00257.19 KXL41522.1 - 1 9.9 11.6 1.4 9.5 11.6 1.1 1 0 0 1 1 1 0 Dehydrin Rxt3 PF08642.10 KXL41522.1 - 1.5 9.6 4.7 0.58 10.9 0.5 1.9 1 1 1 2 2 2 0 Histone deacetylation protein Rxt3 SAP130_C PF16014.5 KXL41522.1 - 1.6 7.8 6.7 1.5 7.8 6.7 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus HNF-1_N PF04814.13 KXL41522.1 - 2.1 8.9 7.9 2.6 8.6 7.9 1.1 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus SMYLE_N PF18615.1 KXL41522.1 - 2.6 7.5 4.4 3.1 7.3 4.4 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain FSA_C PF10479.9 KXL41522.1 - 6.9 4.7 18.3 9.9 4.2 18.3 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF4611 PF15387.6 KXL41522.1 - 9.3 6.5 8.3 12 6.2 7.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) zf-rbx1 PF12678.7 KXL41526.1 - 2.1e-09 37.6 0.2 3.7e-09 36.7 0.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KXL41526.1 - 2.4e-08 34.1 6.4 6e-08 32.9 2.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KXL41526.1 - 6.9e-07 29.1 0.7 1.4e-06 28.1 0.7 1.5 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KXL41526.1 - 1.5e-06 28.0 0.3 2.4e-06 27.3 0.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXL41526.1 - 1.3e-05 24.9 7.6 2.4e-05 24.0 2.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXL41526.1 - 3.1e-05 23.8 1.0 3.5e-05 23.6 0.1 1.5 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KXL41526.1 - 0.00012 22.0 3.9 0.00027 20.9 1.1 2.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXL41526.1 - 0.00034 20.4 0.9 0.00034 20.4 0.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KXL41526.1 - 0.0041 16.7 0.4 0.0083 15.7 0.4 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KXL41526.1 - 0.0046 16.7 9.4 0.015 15.1 0.4 2.9 3 0 0 3 3 3 2 RING-like zinc finger DUF2921 PF11145.8 KXL41526.1 - 0.014 13.3 1.2 0.021 12.7 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) zf-ANAPC11 PF12861.7 KXL41526.1 - 0.015 15.3 0.8 0.031 14.3 0.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3H2C3 PF17122.5 KXL41526.1 - 1.2 9.2 5.6 2.1 8.5 1.6 2.6 2 0 0 2 2 2 0 Zinc-finger FANCL_C PF11793.8 KXL41526.1 - 9.3 6.5 5.5 37 4.6 5.5 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain DUF3619 PF12279.8 KXL41527.1 - 0.056 13.8 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) YEATS PF03366.16 KXL41528.1 - 1.9e-18 66.2 0.0 3.7e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 YEATS family BET PF17035.5 KXL41528.1 - 3.7e-06 27.0 0.3 7.6e-06 26.0 0.3 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation SLX9 PF15341.6 KXL41528.1 - 0.032 14.6 0.2 0.057 13.8 0.2 1.4 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 MgtE_N PF03448.17 KXL41528.1 - 0.11 13.1 0.7 0.19 12.3 0.7 1.3 1 0 0 1 1 1 0 MgtE intracellular N domain Ran_BP1 PF00638.18 KXL41529.1 - 6.2e-49 165.3 0.8 1.1e-48 164.5 0.8 1.4 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 KXL41529.1 - 0.0021 18.0 0.1 0.012 15.5 0.1 2.0 1 1 0 1 1 1 1 WH1 domain VID27_PH PF17747.1 KXL41529.1 - 0.0021 18.3 0.0 0.0033 17.7 0.0 1.3 1 0 0 1 1 1 1 VID27 PH-like domain CDC27 PF09507.10 KXL41529.1 - 5.5 6.3 20.3 7.4 5.8 20.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Sugar_tr PF00083.24 KXL41531.1 - 4e-129 431.4 33.3 4.6e-129 431.2 33.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL41531.1 - 1.5e-20 73.4 41.7 1e-19 70.7 37.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily F_bP_aldolase PF01116.20 KXL41533.1 - 5.4e-96 321.3 0.0 6.1e-96 321.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Methyltransf_25 PF13649.6 KXL41534.1 - 8e-11 42.5 0.0 1.5e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL41534.1 - 6.1e-10 39.6 0.0 9.7e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL41534.1 - 1.9e-08 35.0 0.0 2.9e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL41534.1 - 1.9e-07 31.0 0.0 2.7e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXL41534.1 - 1.2e-05 25.2 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 KXL41534.1 - 0.0012 18.6 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Prp19 PF08606.11 KXL41535.1 - 1.2e-31 108.5 2.8 1.2e-31 108.5 2.8 2.3 2 0 0 2 2 2 1 Prp19/Pso4-like WD40 PF00400.32 KXL41535.1 - 1.3e-15 57.5 7.2 0.0004 21.1 0.0 5.8 4 1 2 6 6 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL41535.1 - 3.2e-15 56.2 0.0 7.2e-07 29.4 0.0 4.8 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KXL41535.1 - 8.9e-05 21.2 0.1 0.0016 17.1 0.0 2.5 1 1 2 3 3 3 1 Cytochrome D1 heme domain eIF2A PF08662.11 KXL41535.1 - 0.00018 21.5 0.0 0.0047 16.8 0.0 2.7 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KXL41535.1 - 0.00055 19.0 0.0 0.00097 18.2 0.0 1.4 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein zf-Nse PF11789.8 KXL41535.1 - 0.0035 17.1 0.0 0.007 16.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit V_ATPase_I_N PF18670.1 KXL41535.1 - 0.0079 16.6 0.1 0.017 15.5 0.1 1.5 1 0 0 1 1 1 1 V-type ATPase subunit I, N-terminal domain VID27 PF08553.10 KXL41535.1 - 0.029 13.4 0.9 0.25 10.3 0.0 2.1 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain DUF3450 PF11932.8 KXL41535.1 - 0.16 11.3 6.7 0.085 12.2 2.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ABC_tran_CTD PF16326.5 KXL41535.1 - 0.21 11.8 5.3 0.18 12.1 0.8 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF1635 PF07795.11 KXL41535.1 - 0.3 10.9 2.1 0.54 10.1 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF3618 PF12277.8 KXL41535.1 - 8 6.8 10.6 21 5.4 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3618) zf-RING_5 PF14634.6 KXL41536.1 - 0.0013 18.6 1.9 0.0021 18.0 1.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXL41536.1 - 0.0037 17.2 0.2 0.0079 16.2 0.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXL41536.1 - 0.017 15.0 0.4 0.04 13.8 0.4 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXL41536.1 - 0.023 15.0 0.6 0.046 14.1 0.6 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.6 KXL41536.1 - 0.052 13.4 1.9 0.17 11.8 1.9 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXL41536.1 - 0.18 11.7 2.6 0.55 10.1 2.6 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXL41536.1 - 0.3 11.0 2.4 1.2 9.1 2.5 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Aldolase_II PF00596.21 KXL41537.1 - 1.7e-16 60.7 0.5 2.2e-16 60.3 0.5 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Aldolase_II PF00596.21 KXL41538.1 - 0.076 12.9 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Class II Aldolase and Adducin N-terminal domain LSM PF01423.22 KXL41539.1 - 2.5e-17 62.3 0.3 3.4e-17 61.9 0.3 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXL41539.1 - 0.018 15.2 0.0 0.026 14.7 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF150_C PF17384.2 KXL41539.1 - 0.12 12.6 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain PGP_phosphatase PF09419.10 KXL41540.1 - 3.5e-53 179.6 0.0 4.1e-53 179.4 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 KXL41540.1 - 4.6e-07 29.8 0.0 7.5e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Beta-lactamase PF00144.24 KXL41542.1 - 9.4e-44 150.0 0.1 1.4e-43 149.4 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 KXL41542.1 - 0.11 11.9 0.0 0.6 9.5 0.0 2.1 2 1 1 3 3 3 0 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 KXL41542.1 - 0.13 11.9 0.0 0.38 10.3 0.0 1.7 2 0 0 2 2 2 0 Beta-lactamase enzyme family Ric8 PF10165.9 KXL41543.1 - 2.6e-122 409.2 0.4 3.1e-122 408.9 0.4 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Rif1_N PF12231.8 KXL41544.1 - 7.2e-123 410.3 0.7 7.2e-123 410.3 0.7 1.7 2 0 0 2 2 2 1 Rap1-interacting factor 1 N terminal WD40 PF00400.32 KXL41545.1 - 4.4e-12 46.3 12.0 0.00061 20.5 0.1 6.0 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL41545.1 - 1.8e-06 28.1 0.0 0.00028 21.1 0.0 3.3 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KXL41545.1 - 0.00044 20.1 0.0 1.2 9.2 0.0 2.9 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KXL41545.1 - 0.012 14.2 0.0 0.021 13.4 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain eIF2A PF08662.11 KXL41545.1 - 0.042 13.7 0.0 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KXL41545.1 - 0.21 10.5 0.0 1.1 8.2 0.0 1.9 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein EF_assoc_2 PF08356.12 KXL41546.1 - 1.8e-32 111.2 0.0 3.8e-32 110.1 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 KXL41546.1 - 3.4e-27 93.9 0.1 6.1e-27 93.0 0.1 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 KXL41546.1 - 1.7e-24 86.3 0.0 3.5e-14 52.7 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KXL41546.1 - 3.6e-12 46.6 0.0 7.8e-07 29.3 0.0 2.7 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KXL41546.1 - 4.5e-08 33.2 0.0 0.00069 19.7 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 KXL41546.1 - 1.1e-05 25.6 0.2 0.082 13.0 0.1 2.5 2 1 0 2 2 2 2 Dynamin family EF-hand_6 PF13405.6 KXL41546.1 - 6e-05 22.6 1.6 0.066 13.2 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KXL41546.1 - 0.0017 17.8 0.6 0.19 11.4 0.1 3.0 3 0 0 3 3 2 1 EF hand EF-hand_7 PF13499.6 KXL41546.1 - 0.0022 18.4 0.2 4.3 7.9 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair AAA_16 PF13191.6 KXL41546.1 - 0.011 16.2 0.0 2 8.8 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain AAA_29 PF13555.6 KXL41546.1 - 0.027 14.2 0.0 3.5 7.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KXL41546.1 - 0.046 14.2 0.0 2.6 8.6 0.0 2.4 2 0 0 2 2 2 0 ABC transporter GTP_EFTU PF00009.27 KXL41546.1 - 0.095 12.2 0.0 16 5.0 0.0 2.8 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KXL41546.1 - 0.13 12.2 0.1 13 5.7 0.0 3.1 3 0 0 3 3 3 0 RsgA GTPase SRPRB PF09439.10 KXL41546.1 - 0.14 11.6 0.0 9.4 5.6 0.0 2.5 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.6 KXL41546.1 - 0.16 12.2 0.0 14 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KXL41546.1 - 0.18 11.1 0.0 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATPase_2 PF01637.18 KXL41546.1 - 0.2 11.6 0.0 5.4 6.9 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea EF-hand_8 PF13833.6 KXL41546.1 - 0.53 10.2 1.6 7.9 6.4 0.3 2.6 2 0 0 2 2 2 0 EF-hand domain pair Zds_C PF08632.10 KXL41547.1 - 1e-28 98.8 1.2 1.9e-28 98.0 1.2 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term PH PF00169.29 KXL41548.1 - 0.00094 19.7 0.0 0.002 18.6 0.0 1.5 1 0 0 1 1 1 1 PH domain BORCS7 PF16088.5 KXL41548.1 - 0.069 13.4 1.2 0.14 12.5 0.2 1.9 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 7 eRF1_3 PF03465.15 KXL41548.1 - 0.099 13.1 0.0 0.43 11.1 0.0 2.0 2 0 0 2 2 2 0 eRF1 domain 3 ApoLp-III PF07464.11 KXL41548.1 - 0.47 10.6 5.0 3.6 7.7 0.0 3.2 4 0 0 4 4 4 0 Apolipophorin-III precursor (apoLp-III) Abhydrolase_3 PF07859.13 KXL41549.1 - 5e-48 163.8 0.0 6e-48 163.5 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXL41549.1 - 0.00016 20.7 0.2 0.00032 19.7 0.0 1.5 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_6 PF12697.7 KXL41549.1 - 0.0075 16.9 0.1 0.014 16.0 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXL41549.1 - 0.054 12.8 0.0 1.7 7.8 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF4097 PF13349.6 KXL41550.1 - 1.1e-08 34.8 8.0 3.3e-06 26.6 1.3 3.2 1 1 2 3 3 3 3 Putative adhesin PTS_2-RNA PF01885.16 KXL41551.1 - 2e-64 217.0 0.0 2.3e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Fungal_trans PF04082.18 KXL41553.1 - 2.5e-28 98.9 0.0 3.9e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL41553.1 - 2.8e-11 43.4 12.6 4.5e-11 42.7 12.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4149 PF13664.6 KXL41554.1 - 7e-24 84.1 0.6 7e-24 84.1 0.6 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4149) Ku_PK_bind PF08785.11 KXL41555.1 - 8.2e-32 109.9 0.0 1.8e-31 108.8 0.0 1.6 1 0 0 1 1 1 1 Ku C terminal domain like Ku PF02735.16 KXL41555.1 - 9.1e-32 110.4 0.0 1.6e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain VWA PF00092.28 KXL41555.1 - 7.8e-05 23.0 1.8 0.00029 21.1 0.3 2.5 2 1 1 3 3 3 1 von Willebrand factor type A domain Abhydrolase_3 PF07859.13 KXL41556.1 - 2.4e-45 155.0 0.0 3.2e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXL41556.1 - 0.0023 16.9 0.0 0.0058 15.6 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KXL41556.1 - 0.0063 16.0 0.0 3.8 6.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 KXL41556.1 - 0.043 13.4 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Say1_Mug180 PF10340.9 KXL41556.1 - 0.082 11.7 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase Glyco_transf_90 PF05686.12 KXL41557.1 - 2.4e-13 49.8 5.6 1e-09 37.8 4.0 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 90 ADH_zinc_N PF00107.26 KXL41558.1 - 1.4e-25 89.7 0.0 2.2e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXL41558.1 - 9e-21 75.3 0.0 1.5e-20 74.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXL41558.1 - 0.00022 21.1 0.1 0.00057 19.7 0.1 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.21 KXL41558.1 - 0.036 13.8 0.2 1.7 8.3 0.1 2.1 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ADH_N_2 PF16884.5 KXL41558.1 - 0.064 13.2 0.0 0.24 11.3 0.0 1.9 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase Metallophos PF00149.28 KXL41559.1 - 2.9e-09 37.7 2.1 5.6e-09 36.8 2.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXL41559.1 - 4.8e-06 26.9 0.2 5.4e-05 23.4 0.2 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF5539 PF17693.1 KXL41560.1 - 0.022 14.4 1.6 0.053 13.2 0.9 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5539) DnaJ PF00226.31 KXL41561.1 - 2.9e-22 78.5 1.8 3.3e-22 78.4 1.8 1.0 1 0 0 1 1 1 1 DnaJ domain SSI PF00720.17 KXL41561.1 - 0.049 13.6 0.0 0.055 13.4 0.0 1.0 1 0 0 1 1 1 0 Subtilisin inhibitor-like FGE-sulfatase PF03781.16 KXL41564.1 - 3.6e-16 59.5 0.1 6.2e-16 58.8 0.1 1.4 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KXL41564.1 - 6.3e-09 36.4 4.6 1.2e-08 35.5 2.6 2.2 1 1 1 2 2 2 1 DinB superfamily HMA PF00403.26 KXL41565.1 - 0.082 13.4 0.1 15 6.1 0.0 2.4 2 1 0 2 2 2 0 Heavy-metal-associated domain SBP_bac_1 PF01547.25 KXL41566.1 - 0.029 14.3 0.0 0.033 14.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Cu-oxidase_2 PF07731.14 KXL41567.1 - 6e-36 123.2 0.0 3.5e-35 120.7 0.1 2.0 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 KXL41567.1 - 1.4e-05 25.2 0.0 3.6e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase HMA PF00403.26 KXL41568.1 - 9.2e-14 51.6 0.0 1.2e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Heavy-metal-associated domain Fer2_BFD PF04324.15 KXL41568.1 - 0.07 13.5 0.2 0.19 12.1 0.1 1.7 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain E1-E2_ATPase PF00122.20 KXL41569.1 - 2e-46 157.8 0.0 7.6e-46 155.9 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.26 KXL41569.1 - 7.1e-35 119.3 0.8 4e-13 49.6 0.0 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 KXL41569.1 - 1.4e-29 103.9 0.7 2.1e-29 103.3 0.7 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KXL41569.1 - 2e-05 24.4 0.0 3.3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase SNAD4 PF18750.1 KXL41569.1 - 0.00011 22.3 0.9 0.058 13.5 0.0 3.5 2 1 0 3 3 3 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 KXL41569.1 - 0.0025 17.9 0.8 0.044 13.9 0.0 2.9 3 0 0 3 3 3 1 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 KXL41569.1 - 0.0068 16.5 0.6 0.12 12.4 0.0 2.8 2 1 1 3 3 3 1 APOBEC2 Pox_E10 PF04805.12 KXL41569.1 - 0.032 14.1 1.4 47 4.0 0.0 4.1 4 0 0 4 4 4 0 E10-like protein conserved region NAD2 PF18782.1 KXL41569.1 - 0.19 11.8 0.1 1.6 8.8 0.0 2.3 1 1 1 2 2 2 0 Novel AID APOBEC clade 2 Tetraspanin PF00335.20 KXL41570.1 - 0.001 18.8 0.1 0.0014 18.4 0.1 1.2 1 0 0 1 1 1 1 Tetraspanin family Cu-oxidase_2 PF07731.14 KXL41571.1 - 1.2e-12 47.8 3.5 2.3e-08 33.9 2.7 3.4 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXL41571.1 - 4.2e-12 46.1 3.1 6.3e-11 42.3 0.1 2.6 2 1 0 2 2 2 2 Multicopper oxidase zf-RING_2 PF13639.6 KXL41572.1 - 2.2e-07 31.1 6.1 2.2e-07 31.1 6.1 2.4 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KXL41572.1 - 7.5e-07 29.4 11.3 9.1e-06 25.9 11.3 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KXL41572.1 - 3.9e-05 23.4 7.7 0.0003 20.6 2.7 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KXL41572.1 - 6.9e-05 22.6 4.2 6.9e-05 22.6 4.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXL41572.1 - 8.9e-05 22.2 3.8 8.9e-05 22.2 3.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXL41572.1 - 0.00015 21.8 4.3 0.001 19.0 4.3 2.4 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXL41572.1 - 0.00055 19.8 8.4 0.0023 17.8 7.9 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXL41572.1 - 0.0027 17.6 9.5 0.013 15.4 8.2 2.3 1 1 1 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KXL41572.1 - 0.0097 15.9 3.2 0.013 15.6 0.4 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KXL41572.1 - 0.027 14.6 1.0 0.027 14.6 1.0 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KXL41572.1 - 0.031 13.9 2.5 0.031 13.9 2.5 1.8 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KXL41572.1 - 0.034 13.9 1.4 0.034 13.9 1.4 2.5 2 0 0 2 2 2 0 RING-like zinc finger Form-deh_trans PF09163.11 KXL41572.1 - 0.092 12.5 0.2 12 5.8 0.0 2.5 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane Zn-ribbon_8 PF09723.10 KXL41572.1 - 0.7 10.1 3.1 0.45 10.7 0.9 1.8 2 0 0 2 2 2 0 Zinc ribbon domain FANCL_C PF11793.8 KXL41572.1 - 5.6 7.2 7.0 77 3.6 7.0 2.7 1 1 0 1 1 1 0 FANCL C-terminal domain MFS_1 PF07690.16 KXL41573.1 - 1.3e-50 172.3 28.1 1.3e-50 172.3 28.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL41573.1 - 1.1e-10 40.9 11.8 1.1e-10 40.9 11.8 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter Octopine_DH PF02317.17 KXL41574.1 - 1.8e-43 148.2 0.0 2.7e-43 147.6 0.0 1.3 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain NAD_Gly3P_dh_N PF01210.23 KXL41574.1 - 8.8e-07 29.0 0.0 2.4e-06 27.6 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 KXL41574.1 - 0.0011 18.7 0.1 0.0031 17.2 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 KXL41574.1 - 0.0023 17.1 0.3 0.0035 16.5 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KXL41574.1 - 0.0028 17.9 0.1 0.0062 16.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXL41574.1 - 0.0033 16.7 0.1 0.007 15.6 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 KXL41574.1 - 0.012 16.2 0.0 0.037 14.6 0.0 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent HI0933_like PF03486.14 KXL41574.1 - 0.039 12.7 0.0 0.063 12.0 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.24 KXL41574.1 - 0.087 12.4 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXL41574.1 - 0.16 11.0 0.1 0.23 10.5 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Cu-oxidase_3 PF07732.15 KXL41576.1 - 3.4e-43 146.4 2.2 5.9e-40 136.0 0.0 3.9 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXL41576.1 - 1.7e-41 141.1 5.2 5.3e-34 116.9 1.4 3.9 3 2 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KXL41576.1 - 6.3e-21 75.1 0.0 1.9e-15 57.3 0.1 2.7 2 0 0 2 2 2 2 Multicopper oxidase Aegerolysin PF06355.13 KXL41577.1 - 4.7e-24 84.9 0.0 6e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Aegerolysin Ctr PF04145.15 KXL41578.1 - 3e-20 73.3 0.0 3.4e-20 73.2 0.0 1.0 1 0 0 1 1 1 1 Ctr copper transporter family UCR_UQCRX_QCR9 PF05365.12 KXL41578.1 - 0.15 12.1 1.2 0.67 9.9 0.1 2.3 2 1 0 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Methyltransf_24 PF13578.6 KXL41579.1 - 6.8e-10 39.9 0.0 9.4e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 KXL41579.1 - 6.1e-08 32.1 0.1 3.6e-07 29.6 0.1 1.9 1 1 0 1 1 1 1 O-methyltransferase Phage_holin_3_5 PF16085.5 KXL41579.1 - 0.034 14.3 0.0 0.065 13.4 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage holin Hol, superfamily III GCD14 PF08704.10 KXL41579.1 - 0.036 13.7 0.0 0.064 12.9 0.0 1.4 1 1 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit E1-E2_ATPase PF00122.20 KXL41580.1 - 6.9e-48 162.6 0.0 2.7e-47 160.6 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.26 KXL41580.1 - 1.2e-31 108.9 0.2 4.5e-11 43.0 0.1 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 KXL41580.1 - 1.8e-31 110.1 0.2 3.2e-31 109.2 0.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KXL41580.1 - 0.00029 20.7 0.1 0.00061 19.6 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXL41580.1 - 0.0097 16.3 0.0 0.025 15.0 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pox_E10 PF04805.12 KXL41580.1 - 0.14 12.0 0.7 32 4.5 0.0 3.7 4 0 0 4 4 4 0 E10-like protein conserved region DDE_3 PF13358.6 KXL41581.1 - 5.5e-13 48.9 0.0 1.2e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KXL41581.1 - 0.15 12.3 0.5 0.25 11.6 0.5 1.4 1 0 0 1 1 1 0 Transposase Nramp PF01566.18 KXL41582.1 - 1.4e-91 307.2 23.3 3.8e-91 305.7 23.3 1.7 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein Methyltransf_23 PF13489.6 KXL41583.1 - 1.2e-13 51.2 0.0 1.8e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL41583.1 - 8.8e-09 35.9 0.0 1.4e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL41583.1 - 4.7e-08 33.6 0.0 7.7e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL41583.1 - 2.5e-07 31.4 0.0 4.2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL41583.1 - 0.00064 19.6 0.0 0.0011 18.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Hydrolase PF00702.26 KXL41584.1 - 3.1e-24 86.5 0.0 8.8e-24 85.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KXL41584.1 - 8.3e-21 74.2 0.1 1.7e-09 38.0 0.0 4.4 4 0 0 4 4 4 3 Heavy-metal-associated domain E1-E2_ATPase PF00122.20 KXL41584.1 - 3.9e-06 26.5 0.2 7.2e-06 25.6 0.2 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KXL41584.1 - 3.5e-05 23.7 0.0 0.00012 21.9 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXL41584.1 - 0.00061 20.3 0.0 0.0023 18.4 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ctr PF04145.15 KXL41585.1 - 1.2e-16 61.7 0.6 1.4e-16 61.5 0.6 1.0 1 0 0 1 1 1 1 Ctr copper transporter family DUF872 PF05915.12 KXL41585.1 - 0.05 13.8 0.7 0.84 9.8 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF4191 PF13829.6 KXL41585.1 - 0.15 11.4 1.0 0.31 10.3 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF2208 PF09973.9 KXL41585.1 - 0.23 11.0 5.2 20 4.7 5.2 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2208) SNARE PF05739.19 KXL41585.1 - 5.8 7.0 6.5 0.74 9.9 0.2 2.4 2 1 0 2 2 2 0 SNARE domain SRF-TF PF00319.18 KXL41590.1 - 2.2e-07 30.2 0.2 2.9e-07 29.9 0.2 1.1 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DDE_1 PF03184.19 KXL41591.1 - 0.00093 18.9 0.0 0.0013 18.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Methyltransf_3 PF01596.17 KXL41592.1 - 0.15 11.2 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase LAGLIDADG_2 PF03161.13 KXL41595.1 - 7e-12 45.7 0.1 7.6e-12 45.6 0.1 1.0 1 0 0 1 1 1 1 LAGLIDADG DNA endonuclease family LAGLIDADG_1 PF00961.19 KXL41596.1 - 8.8e-08 33.1 10.4 6.1e-05 23.9 1.1 3.3 2 1 0 2 2 2 2 LAGLIDADG endonuclease LAGLIDADG_3 PF14528.6 KXL41596.1 - 0.03 14.6 2.4 1.2 9.4 0.4 2.9 2 1 1 3 3 3 0 LAGLIDADG-like domain LAGLIDADG_1 PF00961.19 KXL41597.1 - 4.1e-16 59.8 12.1 8.8e-09 36.3 0.4 3.3 2 1 1 3 3 3 3 LAGLIDADG endonuclease Gpi1 PF05024.15 KXL41597.1 - 0.062 13.4 0.9 4.2 7.4 0.0 2.4 2 1 0 2 2 2 0 N-acetylglucosaminyl transferase component (Gpi1) Cytochrom_B_N_2 PF13631.6 KXL41598.1 - 0.023 14.7 0.0 0.027 14.5 0.0 1.1 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB DUF5542 PF17696.1 KXL41598.1 - 1.6 8.9 3.3 2 8.6 3.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5542) Cytochrom_B_C PF00032.17 KXL41599.1 - 6.8e-10 39.2 0.1 9e-10 38.8 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD ATP-synt_C PF00137.21 KXL41600.1 - 7.5e-12 45.4 14.7 1.1e-11 44.9 14.7 1.3 1 0 0 1 1 1 1 ATP synthase subunit C TMEM213 PF15192.6 KXL41600.1 - 0.073 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 TMEM213 family COX3 PF00510.18 KXL41601.1 - 1.3e-24 87.5 3.3 1.4e-24 87.4 3.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III LAGLIDADG_1 PF00961.19 KXL41602.1 - 2.3e-23 83.1 0.7 3.4e-23 82.6 0.1 1.6 2 0 0 2 2 2 1 LAGLIDADG endonuclease CEP44 PF15007.6 KXL41604.1 - 0.029 14.5 0.0 0.082 13.1 0.0 1.7 2 0 0 2 2 2 0 Centrosomal spindle body, CEP44 adh_short PF00106.25 KXL41605.1 - 1.3e-39 135.7 0.0 1.6e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL41605.1 - 3.9e-39 134.6 0.0 2.3e-33 115.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL41605.1 - 3.2e-05 23.9 0.0 5.2e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL41605.1 - 0.016 14.7 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXL41605.1 - 0.019 14.1 0.0 0.039 13.1 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KXL41605.1 - 0.036 13.1 0.0 0.049 12.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_25 PF13649.6 KXL41605.1 - 0.16 12.7 0.0 1.7 9.4 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain FAD_binding_3 PF01494.19 KXL41606.1 - 1.3e-13 50.9 0.0 1e-12 48.0 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXL41606.1 - 0.0021 18.3 0.0 0.0045 17.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXL41606.1 - 0.0036 16.9 0.0 1 8.9 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KXL41606.1 - 0.022 14.0 0.0 0.18 11.1 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KXL41606.1 - 0.022 14.0 0.0 0.048 12.9 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXL41606.1 - 0.024 13.7 0.1 0.19 10.8 0.1 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXL41606.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SGS PF05002.15 KXL41607.1 - 2.5e-31 107.6 3.8 2.5e-31 107.6 3.8 1.9 2 0 0 2 2 1 1 SGS domain CS PF04969.16 KXL41607.1 - 6.5e-13 49.5 0.0 1.1e-12 48.7 0.0 1.4 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 KXL41607.1 - 5.5e-12 44.8 3.6 0.007 16.4 0.2 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXL41607.1 - 7.1e-07 28.8 4.0 0.056 13.3 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXL41607.1 - 9.6e-06 26.2 10.0 0.00025 21.6 6.2 2.8 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXL41607.1 - 0.00084 19.8 5.4 0.0037 17.8 1.4 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXL41607.1 - 0.00086 19.5 2.8 0.22 12.0 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXL41607.1 - 0.0017 18.4 0.6 9.6 6.7 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXL41607.1 - 0.0022 18.7 4.3 0.0034 18.1 0.1 3.0 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXL41607.1 - 0.0048 16.5 5.1 0.0067 16.1 0.7 3.0 2 1 1 3 3 3 1 TPR repeat SHNi-TPR PF10516.9 KXL41607.1 - 0.013 15.0 3.0 0.64 9.5 0.1 3.2 3 0 0 3 3 3 0 SHNi-TPR TPR_6 PF13174.6 KXL41607.1 - 0.013 16.1 3.2 3 8.7 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat YfiO PF13525.6 KXL41607.1 - 0.014 15.1 1.2 0.029 14.1 1.2 1.5 1 0 0 1 1 1 0 Outer membrane lipoprotein TPR_12 PF13424.6 KXL41607.1 - 0.016 15.5 1.7 0.016 15.5 1.7 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KXL41607.1 - 0.02 14.9 0.5 0.039 14.0 0.5 1.5 1 0 0 1 1 1 0 Putative TPR-like repeat TPR_10 PF13374.6 KXL41607.1 - 0.069 13.0 6.0 0.2 11.5 0.4 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4919 PF16266.5 KXL41607.1 - 0.083 12.8 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) TPR_9 PF13371.6 KXL41607.1 - 0.21 11.8 4.4 0.085 13.0 1.2 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 KXL41607.1 - 0.34 11.0 4.1 0.26 11.4 0.2 2.6 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 KXL41607.1 - 1.7 8.9 3.6 12 6.2 0.0 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat DHHA2 PF02833.14 KXL41608.1 - 9.6e-37 126.3 0.5 1.5e-36 125.7 0.5 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 KXL41608.1 - 5.3e-10 39.4 0.0 1.9e-09 37.6 0.0 1.8 1 1 1 2 2 2 1 DHH family BCDHK_Adom3 PF10436.9 KXL41609.1 - 3.5e-45 153.7 0.0 7.6e-45 152.7 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KXL41609.1 - 2.8e-06 27.8 0.0 8.1e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KXL41609.1 - 0.073 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase USP7_ICP0_bdg PF12436.8 KXL41610.1 - 8.7e-79 264.2 1.3 3.5e-78 262.2 0.2 2.3 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 KXL41610.1 - 1.4e-68 230.7 3.2 5.1e-68 228.8 1.0 2.4 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 KXL41610.1 - 4.6e-48 164.0 0.9 7.7e-48 163.2 0.9 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXL41610.1 - 6.2e-18 65.5 0.0 3.3e-17 63.1 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase COX1 PF00115.20 KXL41611.1 - 2e-16 59.9 12.7 2.1e-16 59.8 12.7 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I COX1 PF00115.20 KXL41612.1 - 1.3e-27 96.8 15.4 1e-14 54.3 2.1 2.0 1 1 1 2 2 2 2 Cytochrome C and Quinol oxidase polypeptide I VPDSG-CTERM PF18205.1 KXL41612.1 - 3 7.7 9.3 10 6.1 2.5 3.0 2 0 0 2 2 2 0 VPDSG-CTERM motif LAGLIDADG_1 PF00961.19 KXL41613.1 - 2.6e-19 70.1 14.6 1.2e-10 42.2 1.8 4.0 2 2 1 3 3 3 3 LAGLIDADG endonuclease LAGLIDADG_3 PF14528.6 KXL41613.1 - 9.5e-05 22.6 0.2 0.021 15.1 0.1 2.4 2 0 0 2 2 2 2 LAGLIDADG-like domain Hom_end PF05204.14 KXL41613.1 - 0.027 14.6 0.0 0.19 11.9 0.0 2.0 2 0 0 2 2 2 0 Homing endonuclease Peptidase_C47 PF05543.13 KXL41613.1 - 0.042 13.4 0.0 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 Staphopain peptidase C47 COX1 PF00115.20 KXL41614.1 - 2.9e-24 85.7 1.2 3.2e-24 85.6 1.2 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Epimerase PF01370.21 KXL41615.1 - 1.1e-37 129.9 0.0 9.6e-37 126.7 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXL41615.1 - 6.4e-34 117.8 0.0 8.7e-33 114.1 0.0 2.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KXL41615.1 - 1.1e-06 28.0 0.1 9.5e-06 25.0 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 KXL41615.1 - 1.5e-06 27.5 0.1 0.00071 18.7 0.1 3.1 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KXL41615.1 - 8.9e-06 25.0 0.0 3.8e-05 23.0 0.0 2.0 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 KXL41615.1 - 0.0017 18.3 2.3 0.071 13.0 0.7 3.0 2 1 0 2 2 2 1 KR domain adh_short PF00106.25 KXL41615.1 - 0.0063 16.0 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Spherulin4 PF12138.8 KXL41616.1 - 1.6e-68 230.9 2.6 1.8e-68 230.7 2.6 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 SNARE PF05739.19 KXL41616.1 - 0.2 11.7 1.0 0.43 10.6 1.0 1.5 1 0 0 1 1 1 0 SNARE domain Spherulin4 PF12138.8 KXL41617.1 - 1.1e-57 195.4 0.0 1.3e-57 195.2 0.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Glycos_transf_1 PF00534.20 KXL41618.1 - 3e-14 52.9 0.0 6.6e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXL41618.1 - 1.5e-12 48.1 0.0 3.3e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.8 KXL41618.1 - 0.00048 20.0 0.0 0.00089 19.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3492) Glyco_trans_1_2 PF13524.6 KXL41618.1 - 0.048 14.0 0.0 0.47 10.9 0.0 2.6 2 1 0 2 2 2 0 Glycosyl transferases group 1 SLAC1 PF03595.17 KXL41619.1 - 3.8e-38 131.6 21.3 4.3e-38 131.4 21.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF4834 PF16118.5 KXL41619.1 - 0.0052 17.7 0.0 0.011 16.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) Proton_antipo_M PF00361.20 KXL41620.1 - 2.6e-07 30.1 3.7 2.6e-07 30.1 3.7 1.6 2 0 0 2 2 2 1 Proton-conducting membrane transporter Oxidored_q4 PF00507.19 KXL41621.1 - 1.1e-26 92.9 7.5 1.3e-26 92.6 7.5 1.2 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 VKOR PF07884.14 KXL41621.1 - 1 9.5 7.2 2.1 8.6 7.2 1.6 1 1 0 1 1 1 0 Vitamin K epoxide reductase family COX1 PF00115.20 KXL41622.1 - 2e-10 40.1 1.0 2.2e-10 40.0 1.0 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Ost4 PF10215.9 KXL41622.1 - 0.079 12.8 1.0 0.079 12.8 1.0 2.3 3 0 0 3 3 3 0 Oligosaccaryltransferase LAGLIDADG_1 PF00961.19 KXL41623.1 - 8.2e-11 42.8 4.1 8.9e-11 42.7 4.1 1.0 1 0 0 1 1 1 1 LAGLIDADG endonuclease LAGLIDADG_2 PF03161.13 KXL41624.1 - 1.7e-12 47.7 0.5 1.9e-12 47.5 0.5 1.0 1 0 0 1 1 1 1 LAGLIDADG DNA endonuclease family LAGLIDADG_1 PF00961.19 KXL41626.1 - 1.2e-10 42.3 1.6 1.2e-10 42.3 1.6 1.4 2 0 0 2 2 2 1 LAGLIDADG endonuclease DUF1951 PF09188.10 KXL41626.1 - 0.023 14.7 1.6 0.03 14.3 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1951) Cas9_PI2 PF18070.1 KXL41626.1 - 0.041 14.6 0.9 0.077 13.7 0.9 1.5 1 0 0 1 1 1 0 CRISPR-Cas9 PI domain ATP-synt_A PF00119.20 KXL41627.1 - 1.3e-35 123.2 26.3 1.5e-35 123.1 26.3 1.0 1 0 0 1 1 1 1 ATP synthase A chain Proton_antipo_M PF00361.20 KXL41628.1 - 7.4e-19 68.0 6.8 7.4e-19 68.0 6.8 2.4 3 0 0 3 3 3 1 Proton-conducting membrane transporter NADH5_C PF06455.11 KXL41628.1 - 3.2e-10 39.9 13.8 8.1e-07 28.8 6.8 2.6 2 0 0 2 2 2 2 NADH dehydrogenase subunit 5 C-terminus DUF5310 PF17237.2 KXL41628.1 - 0.04 13.8 0.7 0.35 10.8 0.0 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5310) Proton_antipo_N PF00662.20 KXL41630.1 - 1.5e-15 57.0 0.5 1.5e-15 57.0 0.5 3.0 2 1 1 3 3 3 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Oxidored_q2 PF00420.24 KXL41631.1 - 6.7e-17 61.0 12.9 7.2e-17 60.9 12.9 1.0 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Ac76 PF05814.11 KXL41631.1 - 1.5 8.9 9.1 2.2 8.3 9.1 1.3 1 0 0 1 1 1 0 Orf76 (Ac76) NADHdh PF00146.21 KXL41632.1 - 4.9e-24 85.2 0.3 5.1e-24 85.1 0.3 1.0 1 0 0 1 1 1 1 NADH dehydrogenase NUMOD3 PF07460.11 KXL41633.1 - 6.1e-06 26.4 0.7 6.1e-06 26.4 0.7 2.0 2 0 0 2 2 2 1 NUMOD3 motif (2 copies) NUMOD1 PF07453.13 KXL41633.1 - 0.00079 19.6 2.8 0.00079 19.6 2.8 1.8 2 0 0 2 2 2 1 NUMOD1 domain Oxidored_q3 PF00499.20 KXL41634.1 - 7.4e-24 84.1 13.8 1e-23 83.7 13.8 1.2 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Claudin_2 PF13903.6 KXL41634.1 - 4.4 7.0 11.1 10 5.8 10.5 1.9 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction BK_channel_a PF03493.18 KXL41635.1 - 0.086 13.0 14.8 3.8 7.8 0.4 3.5 1 1 2 3 3 3 0 Calcium-activated BK potassium channel alpha subunit SH3_5 PF08460.10 KXL41635.1 - 0.19 11.8 18.3 3.5 7.8 0.6 4.2 1 1 4 5 5 5 0 Bacterial SH3 domain MAT1-1-2 PF17043.5 KXL41635.1 - 7.8 6.3 10.3 3.7 7.4 0.6 3.1 2 1 2 4 4 4 0 Mating type protein 1-1-2 of unknown function PhyH PF05721.13 KXL41636.1 - 5.6e-07 30.0 0.0 1.8e-06 28.4 0.0 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) But2 PF09792.9 KXL41637.1 - 2.3e-53 180.4 1.1 2.7e-53 180.2 1.1 1.0 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain CLZ PF16526.5 KXL41640.1 - 0.0032 17.8 2.4 0.011 16.1 0.2 2.1 2 0 0 2 2 2 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SlyX PF04102.12 KXL41640.1 - 0.0083 16.7 0.4 4.8 7.9 0.2 2.4 2 0 0 2 2 2 2 SlyX DUF4200 PF13863.6 KXL41640.1 - 0.023 15.1 0.8 6.5 7.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF1732 PF08340.11 KXL41640.1 - 0.034 14.1 2.9 0.89 9.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1732) bZIP_2 PF07716.15 KXL41640.1 - 0.044 13.9 5.5 0.066 13.3 0.5 2.3 2 0 0 2 2 2 0 Basic region leucine zipper TraY PF05509.11 KXL41640.1 - 0.11 12.5 1.6 0.61 10.2 0.1 2.2 2 0 0 2 2 2 0 TraY domain CENP-F_leu_zip PF10473.9 KXL41640.1 - 0.15 12.1 2.0 8 6.5 0.3 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PRKG1_interact PF15898.5 KXL41640.1 - 0.17 12.8 1.5 2.2 9.2 0.1 2.1 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain CCDC-167 PF15188.6 KXL41640.1 - 0.17 12.3 5.1 9.3 6.7 0.1 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 TMF_TATA_bd PF12325.8 KXL41640.1 - 0.35 11.1 5.4 1.8 8.8 0.3 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Tup_N PF08581.10 KXL41640.1 - 0.65 10.3 3.7 4.3 7.7 1.0 2.1 2 0 0 2 2 2 0 Tup N-terminal Sugar_tr PF00083.24 KXL41641.1 - 3.7e-78 263.4 5.7 8.9e-78 262.2 5.7 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL41641.1 - 5.8e-25 87.9 70.5 1.5e-22 80.0 38.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 KXL41642.1 - 4.7e-56 190.1 0.0 7.4e-55 186.1 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL41642.1 - 1.4e-26 93.3 0.0 2.1e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXL41642.1 - 0.11 12.4 0.1 0.28 11.1 0.1 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXL41642.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain CLTH PF10607.9 KXL41643.1 - 4.6e-25 88.2 0.0 1e-24 87.1 0.0 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KXL41643.1 - 0.018 15.0 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 LisH GIT_CC PF16559.5 KXL41643.1 - 0.27 11.1 2.9 2.6 8.0 0.1 2.6 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor LXG PF04740.12 KXL41643.1 - 0.3 10.8 2.4 0.5 10.0 2.4 1.3 1 0 0 1 1 1 0 LXG domain of WXG superfamily TPR_4 PF07721.14 KXL41643.1 - 1 10.1 5.0 17 6.4 1.8 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Nup188_C PF18378.1 KXL41644.1 - 2.5e-114 382.0 0.0 4e-114 381.3 0.0 1.3 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 KXL41644.1 - 2.6e-56 191.2 1.1 5.2e-38 130.6 0.0 2.8 2 1 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 Complex1_LYR PF05347.15 KXL41645.1 - 6.8e-14 51.7 2.2 8.3e-14 51.4 2.2 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KXL41645.1 - 9.1e-07 29.5 0.8 1.1e-06 29.3 0.8 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KXL41645.1 - 0.02 15.5 1.2 0.065 13.8 1.2 1.8 1 1 0 1 1 1 0 Complex1_LYR-like RlaP PF10127.9 KXL41645.1 - 0.12 12.0 0.1 0.12 11.9 0.1 1.0 1 0 0 1 1 1 0 RNA repair pathway DNA polymerase beta family Amino_oxidase PF01593.24 KXL41646.1 - 5.6e-49 167.6 0.1 2.1e-47 162.5 0.1 2.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXL41646.1 - 3.8e-17 62.3 0.1 9e-17 61.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXL41646.1 - 8.6e-09 35.0 0.7 1.8e-07 30.7 0.7 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXL41646.1 - 2.5e-08 33.9 0.7 4.2e-07 29.9 0.7 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXL41646.1 - 6.6e-07 29.4 0.0 0.0017 18.3 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.14 KXL41646.1 - 0.0005 18.9 0.1 0.00096 18.0 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 KXL41646.1 - 0.00052 19.4 0.3 0.00091 18.6 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KXL41646.1 - 0.00053 19.2 0.0 0.00081 18.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KXL41646.1 - 0.0012 19.4 1.8 0.0024 18.4 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXL41646.1 - 0.0034 16.7 0.7 0.018 14.4 0.7 2.0 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KXL41646.1 - 0.0041 16.4 0.1 0.0075 15.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.18 KXL41646.1 - 0.0057 16.6 0.8 0.0094 15.8 0.1 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Prenylcys_lyase PF07156.14 KXL41646.1 - 0.0083 15.3 0.1 0.015 14.4 0.1 1.3 1 0 0 1 1 1 1 Prenylcysteine lyase FAD_oxidored PF12831.7 KXL41646.1 - 0.012 14.9 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase QueC PF06508.13 KXL41646.1 - 0.079 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC GIDA PF01134.22 KXL41646.1 - 0.2 10.7 3.3 0.28 10.2 0.3 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A WD40 PF00400.32 KXL41647.1 - 8.1e-14 51.8 6.3 2.5e-05 24.9 0.1 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL41647.1 - 4.4e-05 23.7 0.1 0.016 15.5 0.0 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain VID27 PF08553.10 KXL41647.1 - 0.11 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain Ge1_WD40 PF16529.5 KXL41647.1 - 0.13 11.2 0.2 1.9 7.4 0.2 2.5 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Pmp3 PF01679.17 KXL41648.1 - 4.4e-16 58.8 15.9 4.8e-16 58.7 15.9 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator PrgI PF12666.7 KXL41648.1 - 3.2 8.5 6.7 3.8 8.3 6.7 1.2 1 0 0 1 1 1 0 PrgI family protein zf-H2C2_2 PF13465.6 KXL41650.1 - 3.6e-06 27.1 2.6 3.6e-06 27.1 2.6 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KXL41650.1 - 0.00015 22.0 5.9 0.0058 17.0 0.2 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-Di19 PF05605.12 KXL41650.1 - 0.024 14.9 2.0 0.061 13.6 2.0 1.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KXL41650.1 - 0.5 11.3 0.2 0.5 11.3 0.2 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger GATase_4 PF13230.6 KXL41651.1 - 1.7e-14 53.4 0.0 9.2e-13 47.7 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.6 KXL41651.1 - 8.8e-08 32.4 0.0 1.7e-07 31.5 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferase domain YrvL PF14184.6 KXL41651.1 - 0.24 11.5 0.0 0.39 10.8 0.0 1.2 1 0 0 1 1 1 0 Regulatory protein YrvL Fungal_trans PF04082.18 KXL41652.1 - 1.1e-17 64.0 1.2 1.7e-17 63.3 0.4 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KXL41652.1 - 4.7e-10 39.4 12.4 0.00013 22.2 3.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXL41652.1 - 3.8e-07 30.2 12.5 2.3e-06 27.8 7.1 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXL41652.1 - 4.5e-05 23.9 12.0 0.038 14.8 2.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KXL41652.1 - 8.5 6.2 8.5 14 5.5 0.9 2.8 2 0 0 2 2 2 0 zinc-finger C2H2-type SUR7 PF06687.12 KXL41654.1 - 3e-35 121.8 16.6 3.8e-35 121.4 16.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family WD40 PF00400.32 KXL41655.1 - 1.3e-18 67.0 2.2 0.033 15.1 0.1 8.5 8 0 0 8 8 8 6 WD domain, G-beta repeat PQQ_2 PF13360.6 KXL41655.1 - 0.00019 21.1 0.1 0.0016 18.1 0.1 2.4 2 0 0 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.16 KXL41655.1 - 0.059 11.9 0.1 9.6 4.6 0.0 2.8 3 0 0 3 3 3 0 Cytochrome D1 heme domain Cyclin_N PF00134.23 KXL41656.1 - 1.7e-36 124.7 0.5 4e-36 123.6 0.5 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXL41656.1 - 4e-14 52.7 0.1 4.5e-13 49.3 0.1 2.4 1 1 0 1 1 1 1 Cyclin, C-terminal domain DUF3306 PF11748.8 KXL41656.1 - 0.15 12.9 0.3 0.38 11.6 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) VATC PF18716.1 KXL41657.1 - 0.0056 16.5 0.8 1.5 8.7 0.1 2.1 2 0 0 2 2 2 2 Vms1-associating treble clef domain Biotin_lipoyl PF00364.22 KXL41659.1 - 1.8e-19 69.3 0.2 4.1e-19 68.2 0.2 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KXL41659.1 - 1.3e-10 41.5 0.0 4e-10 39.9 0.0 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KXL41659.1 - 0.0076 16.1 0.0 0.06 13.2 0.0 2.4 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 KXL41659.1 - 0.019 15.7 0.3 1.2 9.8 0.0 3.2 2 1 1 3 3 3 0 HlyD family secretion protein MRI PF15325.6 KXL41659.1 - 0.029 15.5 4.3 0.08 14.0 4.3 1.7 1 0 0 1 1 1 0 Modulator of retrovirus infection FMN_dh PF01070.18 KXL41660.1 - 6.9e-25 87.8 0.0 7.5e-25 87.7 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KXL41660.1 - 0.011 14.8 0.1 0.018 14.0 0.1 1.3 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 KXL41660.1 - 0.016 14.7 0.0 0.021 14.3 0.0 1.1 1 0 0 1 1 1 0 Histidine biosynthesis protein IMS PF00817.20 KXL41661.1 - 3.4e-41 140.7 0.4 1.1e-40 139.1 0.3 2.0 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 KXL41661.1 - 2e-15 57.5 0.3 5e-15 56.2 0.3 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KXL41661.1 - 0.00054 20.1 0.0 0.0015 18.7 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif Vps36-NZF-N PF16988.5 KXL41661.1 - 0.19 11.2 1.4 0.59 9.6 0.3 2.3 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Abhydrolase_1 PF00561.20 KXL41663.1 - 4.6e-15 55.9 0.2 1.5e-14 54.3 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXL41663.1 - 2.2e-12 46.7 0.0 4.4e-12 45.8 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXL41663.1 - 1.3e-11 45.6 0.1 2e-11 44.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 KXL41663.1 - 0.021 14.8 0.1 0.48 10.3 0.1 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DnaJ-X PF14308.6 KXL41664.1 - 1.1e-75 253.7 4.2 1.1e-75 253.7 4.2 2.6 2 1 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 KXL41664.1 - 3.2e-25 88.0 0.8 7.4e-25 86.9 0.8 1.7 1 0 0 1 1 1 1 DnaJ domain IQ PF00612.27 KXL41665.1 - 3.5e-06 26.3 0.3 9e-06 25.1 0.3 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Feld-I_B PF09252.10 KXL41665.1 - 0.022 14.7 0.1 0.049 13.6 0.1 1.6 1 0 0 1 1 1 0 Allergen Fel d I-B chain DUF2407_C PF13373.6 KXL41666.1 - 0.089 13.0 0.0 0.095 12.9 0.0 1.1 1 0 0 1 1 1 0 DUF2407 C-terminal domain ANTH PF07651.16 KXL41667.1 - 3.8e-62 209.8 2.7 5.3e-62 209.3 2.7 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 KXL41667.1 - 0.00011 22.2 0.0 0.00023 21.2 0.0 1.5 1 0 0 1 1 1 1 ENTH domain Adaptin_N PF01602.20 KXL41667.1 - 0.02 13.5 0.1 0.03 12.9 0.1 1.3 1 0 0 1 1 1 0 Adaptin N terminal region DUF4588 PF15251.6 KXL41667.1 - 6.2 6.5 8.1 0.2 11.4 1.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4588) PALP PF00291.25 KXL41668.1 - 6.5e-76 255.6 0.8 8.5e-76 255.2 0.8 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KXL41668.1 - 3.6e-43 145.2 0.0 1.8e-21 75.7 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase HIG_1_N PF04588.13 KXL41669.1 - 2.1e-21 75.9 0.0 3.4e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region MAS20 PF02064.15 KXL41669.1 - 0.004 17.2 1.9 0.0078 16.3 1.9 1.6 1 0 0 1 1 1 1 MAS20 protein import receptor FAM165 PF14981.6 KXL41669.1 - 1.6 8.6 4.3 0.76 9.6 1.1 2.1 2 0 0 2 2 2 0 FAM165 family Atg31 PF09795.9 KXL41670.1 - 0.0034 17.4 0.2 0.0046 17.0 0.2 1.2 1 0 0 1 1 1 1 Autophagy-related protein 31 MFS_1 PF07690.16 KXL41671.1 - 7e-46 156.8 47.1 7e-46 156.8 47.1 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL41671.1 - 2.1e-15 56.5 2.5 2.1e-15 56.5 2.5 2.7 2 0 0 2 2 2 1 Sugar (and other) transporter CYYR1 PF10873.8 KXL41671.1 - 0.56 10.6 3.1 1.6 9.2 3.1 1.8 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Ribosomal_L36 PF00444.18 KXL41672.1 - 1.3e-17 63.7 12.6 1.3e-17 63.7 12.6 2.2 2 1 0 2 2 2 1 Ribosomal protein L36 PAD_M PF08527.10 KXL41672.1 - 0.06 13.0 0.3 0.07 12.8 0.3 1.1 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) middle domain DUF3340 PF11818.8 KXL41673.1 - 0.034 14.3 0.6 0.034 14.3 0.6 2.2 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) OrfB_IS605 PF01385.19 KXL41673.1 - 0.09 13.0 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 Probable transposase FUSC PF04632.12 KXL41673.1 - 0.85 8.1 3.5 1.3 7.5 3.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4482 PF14818.6 KXL41673.1 - 1.3 9.9 7.3 0.68 10.8 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) Abhydrolase_6 PF12697.7 KXL41674.1 - 1.8e-12 48.3 0.5 4.9e-12 46.9 0.3 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXL41674.1 - 4.9e-09 36.2 0.0 8.5e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXL41674.1 - 1.2e-06 27.9 0.1 5.9e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KXL41674.1 - 0.00089 19.2 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXL41674.1 - 0.0023 17.4 0.0 1.9 7.9 0.0 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF676 PF05057.14 KXL41674.1 - 0.0097 15.4 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) NOG1_N PF17835.1 KXL41674.1 - 0.027 14.4 0.0 0.043 13.8 0.0 1.2 1 0 0 1 1 1 0 NOG1 N-terminal helical domain Peptidase_S15 PF02129.18 KXL41674.1 - 0.085 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) AMP-binding PF00501.28 KXL41675.1 - 2.2e-70 237.4 0.1 5.8e-70 236.0 0.1 1.6 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXL41675.1 - 2.1e-13 51.1 0.4 8.9e-13 49.0 0.2 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF3336 PF11815.8 KXL41676.1 - 1.1e-34 119.1 2.6 2e-34 118.3 2.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KXL41676.1 - 8e-19 68.6 0.0 1.7e-18 67.6 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase Na_H_Exchanger PF00999.21 KXL41677.1 - 3.6e-62 210.3 44.8 4.9e-62 209.9 44.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CoatB PF10389.9 KXL41677.1 - 1.6 8.6 5.0 34 4.4 0.2 3.3 2 0 0 2 2 2 0 Bacteriophage coat protein B Glyco_hydro_92 PF07971.12 KXL41678.1 - 1.9e-138 462.3 1.1 2.2e-138 462.0 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KXL41678.1 - 9.7e-49 166.4 1.4 1.5e-48 165.7 1.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain SnoaL_2 PF12680.7 KXL41679.1 - 0.057 14.1 0.0 0.12 13.1 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain Ost5 PF05251.12 KXL41680.1 - 0.027 14.7 0.1 0.038 14.3 0.1 1.2 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit 5 Es2 PF09751.9 KXL41682.1 - 7.5e-118 395.0 18.4 8.9e-118 394.7 18.4 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 JmjC PF02373.22 KXL41683.1 - 1e-38 132.3 1.8 2.4e-38 131.1 1.8 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H PF13771.6 KXL41683.1 - 3.6e-19 68.8 1.9 3.6e-19 68.8 1.9 1.9 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KXL41683.1 - 5e-18 65.3 1.5 9.6e-18 64.4 1.5 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain JmjN PF02375.17 KXL41683.1 - 1.1e-15 57.2 0.8 4e-15 55.5 0.8 2.1 1 0 0 1 1 1 1 jmjN domain PHD PF00628.29 KXL41683.1 - 4.3 7.3 9.7 9.2 6.3 6.7 2.5 2 0 0 2 2 2 0 PHD-finger Cellulase PF00150.18 KXL41684.1 - 3.3e-20 72.7 12.0 6.9e-20 71.6 12.0 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Acetyltransf_3 PF13302.7 KXL41685.1 - 1.4e-23 84.1 0.0 2.1e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KXL41685.1 - 0.0025 17.5 0.5 0.094 12.4 0.3 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXL41685.1 - 0.022 14.7 0.0 6.7 6.8 0.0 2.2 2 0 0 2 2 2 0 FR47-like protein 3Beta_HSD PF01073.19 KXL41686.1 - 1.5e-52 178.4 0.0 1.8e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXL41686.1 - 1.9e-34 119.2 0.0 2.7e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXL41686.1 - 3.4e-17 62.9 0.0 2.3e-16 60.1 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KXL41686.1 - 1.8e-10 40.4 0.0 2.5e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KXL41686.1 - 6.8e-10 38.5 0.0 2.3e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KXL41686.1 - 1.3e-09 38.2 0.0 2.3e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXL41686.1 - 4.9e-07 29.2 0.1 4.1e-05 22.9 0.4 2.6 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 KXL41686.1 - 6.3e-06 26.2 0.2 1.7e-05 24.8 0.2 1.6 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 KXL41686.1 - 0.00022 20.8 0.0 0.00035 20.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 KXL41686.1 - 0.00091 18.8 0.0 0.0022 17.6 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family adh_short_C2 PF13561.6 KXL41686.1 - 0.006 16.2 0.0 0.0095 15.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Sacchrp_dh_NADP PF03435.18 KXL41686.1 - 0.019 15.2 0.0 0.049 13.9 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain WD40 PF00400.32 KXL41688.1 - 8.8e-17 61.2 11.2 0.0014 19.4 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL41688.1 - 1.9e-05 24.9 0.0 0.041 14.2 0.0 4.0 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KXL41688.1 - 0.055 13.4 0.4 23 5.1 0.0 3.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat RRM_1 PF00076.22 KXL41689.1 - 5.5e-08 32.5 0.0 1.1e-07 31.6 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXL41689.1 - 0.044 13.7 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Autophagy_act_C PF03987.15 KXL41690.1 - 9.2e-10 39.0 0.1 1.2e-09 38.6 0.1 1.1 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Aa_trans PF01490.18 KXL41691.1 - 4.6e-18 65.1 37.2 1.4e-17 63.5 37.2 1.6 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Hexapep PF00132.24 KXL41692.1 - 1.1e-05 25.0 6.9 0.0093 15.7 2.0 3.3 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 KXL41692.1 - 0.00017 21.3 0.0 0.00026 20.7 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KXL41692.1 - 0.0013 19.2 0.1 0.0025 18.2 0.1 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 KXL41692.1 - 0.0046 15.2 0.5 0.0067 14.6 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 KXL41692.1 - 0.021 13.8 0.2 0.03 13.3 0.2 1.1 1 0 0 1 1 1 0 L-fucokinase Hexapep_2 PF14602.6 KXL41692.1 - 0.056 13.2 9.6 0.22 11.3 6.0 3.0 2 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase SnoaL_2 PF12680.7 KXL41693.1 - 0.14 12.8 0.0 0.25 12.0 0.0 1.4 1 1 0 1 1 1 0 SnoaL-like domain RhoGAP PF00620.27 KXL41694.1 - 5.2e-26 91.3 0.1 7.3e-26 90.8 0.1 1.2 1 0 0 1 1 1 1 RhoGAP domain Nod1 PF17114.5 KXL41694.1 - 0.0079 16.4 0.1 0.013 15.7 0.1 1.3 1 0 0 1 1 1 1 Gef2-related medial cortical node protein Nod1 Prenyltrans PF00432.21 KXL41696.1 - 1.9e-60 200.2 10.6 4.5e-13 48.7 0.1 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KXL41696.1 - 0.00098 18.3 0.0 0.0099 15.0 0.0 2.3 1 1 2 3 3 3 1 Squalene-hopene cyclase C-terminal domain zf-C2H2_2 PF12756.7 KXL41697.1 - 0.072 13.4 0.2 0.12 12.7 0.2 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) FAM110_C PF14160.6 KXL41697.1 - 0.073 14.1 0.1 0.24 12.5 0.1 1.9 1 0 0 1 1 1 0 Centrosome-associated C terminus Zn_clus PF00172.18 KXL41698.1 - 6.4e-10 39.0 8.6 1.3e-09 38.0 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXL41698.1 - 2e-08 33.4 2.7 3.9e-08 32.5 2.3 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain MgsA_C PF12002.8 KXL41699.1 - 9.6e-59 198.1 0.0 1.6e-58 197.4 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 KXL41699.1 - 1.9e-21 76.2 0.1 5.2e-21 74.8 0.1 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 KXL41699.1 - 8.3e-15 55.4 0.0 2e-14 54.1 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXL41699.1 - 1.1e-09 38.2 0.0 2.5e-09 37.1 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 KXL41699.1 - 1.3e-05 24.9 0.0 0.00063 19.5 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 KXL41699.1 - 2.2e-05 24.3 0.0 8.8e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXL41699.1 - 4e-05 24.1 0.3 0.023 15.1 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KXL41699.1 - 9.3e-05 22.4 0.2 0.002 18.1 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KXL41699.1 - 0.00012 21.6 0.1 0.14 11.6 0.0 2.2 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KXL41699.1 - 0.00037 20.8 0.1 0.0013 19.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 KXL41699.1 - 0.00048 20.2 0.1 0.003 17.7 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 KXL41699.1 - 0.0011 19.0 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KXL41699.1 - 0.0014 18.9 0.5 0.0044 17.3 0.4 1.8 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.6 KXL41699.1 - 0.0062 16.9 0.3 0.046 14.1 0.4 2.0 1 1 1 2 2 2 1 AAA domain ResIII PF04851.15 KXL41699.1 - 0.01 15.9 0.5 0.28 11.2 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit TRAF6_Z2 PF18048.1 KXL41699.1 - 0.012 15.7 2.4 0.012 15.7 2.4 1.7 2 0 0 2 2 1 0 TNF receptor-associated factor 6 zinc finger 2 DUF815 PF05673.13 KXL41699.1 - 0.013 14.7 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 KXL41699.1 - 0.014 15.1 0.2 0.05 13.3 0.2 1.9 1 1 0 1 1 1 0 AAA domain SKI PF01202.22 KXL41699.1 - 0.016 15.3 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase AAA_24 PF13479.6 KXL41699.1 - 0.027 14.2 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KXL41699.1 - 0.029 13.6 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain TsaE PF02367.17 KXL41699.1 - 0.049 13.6 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 KXL41699.1 - 0.063 12.6 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 KXL41699.1 - 0.12 12.9 0.1 0.4 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KXL41699.1 - 0.14 12.6 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXL41699.1 - 0.15 12.2 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain zf-WRNIP1_ubi PF18279.1 KXL41699.1 - 0.32 11.7 2.2 0.85 10.4 2.2 1.8 1 0 0 1 1 1 0 Werner helicase-interacting protein 1 ubiquitin-binding domain VP40 PF07447.12 KXL41700.1 - 0.18 10.9 0.0 0.2 10.7 0.0 1.0 1 0 0 1 1 1 0 Matrix protein VP40 Septin PF00735.18 KXL41701.1 - 1e-10 41.4 0.0 3.1e-10 39.8 0.0 1.7 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KXL41701.1 - 0.00021 21.4 0.0 0.00047 20.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KXL41701.1 - 0.00033 20.8 0.0 0.00065 19.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 KXL41701.1 - 0.009 16.0 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 KXL41701.1 - 0.01 16.2 0.0 0.024 15.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KXL41701.1 - 0.013 16.0 0.0 0.029 14.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Dynamin_N PF00350.23 KXL41701.1 - 0.029 14.4 0.0 12 5.9 0.0 2.7 2 0 0 2 2 2 0 Dynamin family Arf PF00025.21 KXL41701.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family Roc PF08477.13 KXL41701.1 - 0.21 11.8 0.0 0.48 10.7 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase NTF2 PF02136.20 KXL41702.1 - 2.9e-27 95.6 1.2 5.8e-27 94.7 1.2 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 KXL41702.1 - 3.1e-07 30.1 0.2 6e-07 29.2 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KXL41702.1 - 0.078 13.0 0.1 0.078 13.0 0.1 2.4 2 0 0 2 2 2 0 RNA binding motif Exo_endo_phos PF03372.23 KXL41703.1 - 9.1e-09 35.2 0.1 1.2e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Phage_CI_C PF16452.5 KXL41703.1 - 0.052 13.8 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage CI repressor C-terminal domain p450 PF00067.22 KXL41704.1 - 1.2e-24 86.9 0.0 1.4e-24 86.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ank_2 PF12796.7 KXL41706.1 - 0.068 13.8 0.0 0.099 13.2 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Bac_rhamnosid_C PF17390.2 KXL41707.1 - 8.1e-15 54.4 0.1 2e-14 53.2 0.1 1.7 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid6H PF17389.2 KXL41707.1 - 5.1e-13 49.0 0.8 5.1e-13 49.0 0.8 1.7 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Glyco_hydro_36 PF17167.4 KXL41707.1 - 6.7e-08 31.6 0.0 1.4e-07 30.6 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase 36 superfamily, catalytic domain GDE_C PF06202.14 KXL41707.1 - 7.6e-08 31.7 0.0 1.3e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Trehalase PF01204.18 KXL41707.1 - 0.00018 20.5 0.0 0.00025 20.0 0.0 1.1 1 0 0 1 1 1 1 Trehalase DUF608 PF04685.13 KXL41707.1 - 0.0018 17.5 0.2 0.0027 17.0 0.2 1.2 1 0 0 1 1 1 1 Glycosyl-hydrolase family 116, catalytic region Bac_rhamnosid PF05592.11 KXL41707.1 - 0.028 14.4 0.0 0.11 12.5 0.0 2.0 1 1 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain Glyco_hydro_100 PF12899.7 KXL41707.1 - 0.12 11.0 1.0 3.2 6.3 0.0 2.1 2 0 0 2 2 2 0 Alkaline and neutral invertase Rhodanese PF00581.20 KXL41708.1 - 7.9e-20 71.4 0.0 4.8e-10 39.9 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain HAD_2 PF13419.6 KXL41708.1 - 0.19 11.8 0.0 0.33 11.0 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase WD40 PF00400.32 KXL41709.1 - 5e-25 87.3 12.4 8.1e-07 29.7 0.0 6.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL41709.1 - 4.3e-13 49.4 2.4 0.0001 22.6 0.1 4.2 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXL41709.1 - 0.11 11.4 0.0 0.21 10.5 0.0 1.4 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein LRR_8 PF13855.6 KXL41712.1 - 3.7e-10 39.4 9.4 1e-07 31.6 1.2 3.2 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KXL41712.1 - 8.6e-10 38.7 12.4 6e-05 23.3 1.5 4.3 2 1 4 6 6 6 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KXL41712.1 - 0.0005 19.9 9.6 16 5.9 0.1 5.6 5 0 0 5 5 5 2 Leucine Rich repeat LRR_9 PF14580.6 KXL41712.1 - 0.0011 18.5 2.2 0.012 15.1 1.2 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KXL41712.1 - 0.0023 18.2 8.5 14 6.7 0.5 5.9 5 0 0 5 5 5 2 Leucine Rich Repeat Metallophos PF00149.28 KXL41713.1 - 2.1e-40 139.4 0.1 2.7e-40 139.0 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KXL41713.1 - 5.5e-23 81.2 1.8 7.9e-23 80.6 1.1 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain zf-C2H2 PF00096.26 KXL41717.1 - 0.0061 17.0 16.7 3.5 8.3 0.1 5.3 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXL41717.1 - 0.26 12.2 18.2 10 7.2 0.2 5.3 5 1 0 5 5 5 0 C2H2-type zinc finger Metallophos PF00149.28 KXL41718.1 - 7.5e-13 49.4 0.0 1.1e-12 48.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXL41718.1 - 0.00039 20.6 0.0 0.0029 17.8 0.0 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain GCD14 PF08704.10 KXL41719.1 - 0.00038 20.2 0.0 0.09 12.4 0.0 2.1 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit GCD14_N PF14801.6 KXL41719.1 - 0.00057 19.7 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_24 PF13578.6 KXL41719.1 - 0.002 19.1 0.1 0.005 17.8 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL41719.1 - 0.034 14.8 0.1 5.1 7.9 0.0 2.9 2 1 1 3 3 3 0 Methyltransferase domain DUF2958 PF11171.8 KXL41719.1 - 0.095 13.0 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2958) Phostensin_N PF13916.6 KXL41720.1 - 0.01 16.1 0.5 0.017 15.4 0.5 1.4 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal Spem1 PF15670.5 KXL41720.1 - 0.033 13.8 0.3 0.042 13.4 0.3 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 DUF3915 PF13054.6 KXL41720.1 - 0.13 12.2 4.8 0.19 11.7 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) NICE-1 PF15845.5 KXL41720.1 - 0.25 12.2 7.5 0.42 11.4 7.5 1.3 1 0 0 1 1 1 0 Cysteine-rich C-terminal 1 family Afi1 PF07792.12 KXL41721.1 - 2.2e-41 141.5 0.2 2.2e-41 141.5 0.2 1.7 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.10 KXL41721.1 - 2.1e-37 127.5 0.0 3.7e-37 126.8 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 KXL41721.1 - 1.6e-08 33.7 0.2 0.011 14.5 0.0 4.0 2 2 2 4 4 4 2 Transport protein Avl9 DUF2347 PF09804.9 KXL41721.1 - 0.00044 19.9 0.0 0.042 13.4 0.0 2.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) Cwf_Cwc_15 PF04889.12 KXL41721.1 - 0.028 14.2 7.2 0.05 13.3 7.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein QWRF PF04484.12 KXL41721.1 - 0.33 10.6 4.0 0.62 9.8 4.0 1.3 1 0 0 1 1 1 0 QWRF family Nop53 PF07767.11 KXL41721.1 - 0.35 10.2 8.1 0.64 9.4 8.1 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nop14 PF04147.12 KXL41721.1 - 0.53 8.4 7.8 0.8 7.8 7.8 1.2 1 0 0 1 1 1 0 Nop14-like family Astro_capsid_p PF12226.8 KXL41721.1 - 0.75 8.9 4.6 1.5 7.9 4.6 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RXT2_N PF08595.11 KXL41721.1 - 1 9.4 4.6 2.3 8.2 4.6 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF4746 PF15928.5 KXL41721.1 - 1.1 8.7 5.0 1.9 7.8 5.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RNA_pol_3_Rpc31 PF11705.8 KXL41721.1 - 3 8.0 14.4 5.9 7.1 14.4 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF4611 PF15387.6 KXL41721.1 - 5.4 7.3 11.2 1.1e+02 3.2 11.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) CDC45 PF02724.14 KXL41721.1 - 7.4 4.7 8.9 12 4.1 8.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Nucleo_P87 PF07267.11 KXL41721.1 - 7.4 5.3 5.5 12 4.6 5.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 EF-hand_6 PF13405.6 KXL41722.1 - 4.9e-10 38.5 0.0 1e-06 28.2 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KXL41722.1 - 4.1e-07 30.4 0.1 0.0011 19.3 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KXL41722.1 - 6.1e-07 28.5 0.0 2.9e-05 23.3 0.1 2.5 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 KXL41722.1 - 2.3e-05 23.7 0.3 7.7e-05 22.0 0.1 2.0 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.6 KXL41722.1 - 0.0019 18.5 0.0 2.7 8.4 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain Mucin PF01456.17 KXL41722.1 - 0.089 12.8 25.5 0.26 11.3 11.6 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein Acetyltransf_1 PF00583.25 KXL41723.1 - 1.6e-10 41.3 0.0 1.9e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXL41723.1 - 5.2e-07 30.0 0.1 1.2e-06 28.9 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXL41723.1 - 7.2e-07 29.2 0.0 1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXL41723.1 - 9.6e-07 28.7 0.0 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 KXL41723.1 - 0.00016 21.9 0.0 0.00018 21.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXL41723.1 - 0.0032 17.5 0.0 0.0053 16.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KXL41723.1 - 0.11 13.1 0.0 0.16 12.7 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Isochorismatase PF00857.20 KXL41724.1 - 7.9e-30 104.3 0.0 9.7e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Chitin_bind_1 PF00187.19 KXL41724.1 - 0.17 12.4 0.7 9.3 6.8 0.1 2.3 2 0 0 2 2 2 0 Chitin recognition protein Hydrolase_4 PF12146.8 KXL41727.1 - 2.2e-45 154.8 0.0 2.8e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXL41727.1 - 1.9e-10 41.7 0.0 2.4e-10 41.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXL41727.1 - 2.7e-09 37.0 0.1 6.1e-09 35.9 0.0 1.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF1749 PF08538.10 KXL41727.1 - 0.00026 20.2 0.0 0.00041 19.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Peptidase_S9 PF00326.21 KXL41727.1 - 0.002 17.7 0.0 0.0047 16.4 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Thioesterase PF00975.20 KXL41727.1 - 0.083 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Chlorophyllase PF07224.11 KXL41727.1 - 0.11 11.5 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Esterase PF00756.20 KXL41727.1 - 0.14 11.7 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Chlorophyllase2 PF12740.7 KXL41727.1 - 0.15 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DLH PF01738.18 KXL41727.1 - 0.17 11.4 0.0 10 5.6 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family FAD_binding_3 PF01494.19 KXL41728.1 - 4.8e-38 131.3 0.0 6.4e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXL41728.1 - 0.0015 18.8 0.0 0.0046 17.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXL41728.1 - 0.002 17.8 0.0 0.38 10.3 0.0 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXL41728.1 - 0.0058 16.6 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KXL41728.1 - 0.02 14.0 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXL41728.1 - 0.028 13.7 0.0 0.19 10.9 0.0 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KXL41728.1 - 0.046 12.8 0.0 0.062 12.3 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Thi4 PF01946.17 KXL41728.1 - 0.083 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KXL41728.1 - 0.14 10.8 0.0 0.25 10.0 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Abhydrolase_2 PF02230.16 KXL41729.1 - 0.0017 18.2 0.0 0.0019 18.0 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DUF2838 PF10998.8 KXL41730.1 - 1.7e-42 144.2 12.5 1.7e-42 144.2 12.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Atg14 PF10186.9 KXL41730.1 - 0.42 9.7 2.7 0.66 9.0 2.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Lactamase_B PF00753.27 KXL41732.1 - 3.8e-18 66.2 5.7 5.2e-18 65.8 5.7 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXL41732.1 - 0.0015 18.1 0.5 0.0023 17.5 0.5 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Acetyltransf_10 PF13673.7 KXL41733.1 - 6.9e-11 42.2 0.1 1.9e-10 40.8 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXL41733.1 - 1.4e-08 34.9 0.1 2.5e-08 34.2 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXL41733.1 - 5.1e-08 33.2 0.1 9.9e-08 32.3 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXL41733.1 - 0.00031 20.7 0.0 0.00057 19.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KXL41733.1 - 0.0067 16.5 2.8 0.014 15.5 0.1 2.4 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 KXL41734.1 - 4.7e-27 94.8 22.1 4.7e-27 94.8 22.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3040 PF11239.8 KXL41734.1 - 0.69 10.2 3.3 0.58 10.5 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Sugar_tr PF00083.24 KXL41737.1 - 3.7e-116 388.7 26.7 6.5e-116 387.8 26.7 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL41737.1 - 1.4e-23 83.5 45.2 1.5e-16 60.3 17.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CHD5 PF04420.14 KXL41737.1 - 0.35 10.7 2.1 0.92 9.3 2.1 1.7 1 0 0 1 1 1 0 CHD5-like protein HTH_psq PF05225.16 KXL41738.1 - 0.00034 20.3 1.3 0.00045 19.9 1.3 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain SpoIIID PF12116.8 KXL41738.1 - 0.066 13.3 0.1 0.082 13.0 0.1 1.3 1 0 0 1 1 1 0 Stage III sporulation protein D MFS_1 PF07690.16 KXL41739.1 - 3.4e-19 69.0 44.4 6.1e-16 58.3 21.0 2.2 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 KXL41739.1 - 0.0026 16.2 2.1 0.0042 15.5 2.1 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector Chromo PF00385.24 KXL41741.1 - 3.5e-11 42.8 0.1 7e-11 41.9 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 KXL41741.1 - 2.4e-07 30.8 0.1 1.1e-06 28.7 0.0 2.0 2 0 0 2 2 2 1 Chromo shadow domain Cpn60_TCP1 PF00118.24 KXL41742.1 - 1.6e-156 521.8 0.4 1.8e-156 521.6 0.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SNF2_N PF00176.23 KXL41743.1 - 3.8e-64 216.6 1.0 2.5e-62 210.6 1.0 3.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXL41743.1 - 2.4e-15 56.8 0.0 9e-15 55.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL41743.1 - 8e-07 29.2 0.0 3e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KXL41743.1 - 8.5e-06 25.6 0.0 1.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DZR PF12773.7 KXL41743.1 - 0.1 12.6 1.0 0.21 11.6 1.0 1.4 1 0 0 1 1 1 0 Double zinc ribbon DUF5072 PF16807.5 KXL41743.1 - 0.16 12.0 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5072) zf-HIT PF04438.16 KXL41743.1 - 0.65 9.9 1.8 2.6 8.0 0.2 2.2 2 0 0 2 2 2 0 HIT zinc finger A_deaminase PF00962.22 KXL41744.1 - 2.1e-21 76.6 0.1 8.2e-20 71.4 0.0 2.3 2 0 0 2 2 2 2 Adenosine/AMP deaminase A_deaminase_N PF08451.11 KXL41744.1 - 0.00028 21.1 0.0 0.00055 20.2 0.0 1.5 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal ketoacyl-synt PF00109.26 KXL41746.1 - 0.11 12.0 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Isochorismatase PF00857.20 KXL41747.1 - 4.1e-16 59.6 0.0 5.8e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family DUF543 PF04418.12 KXL41748.1 - 1.3e-29 101.9 0.0 1.6e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Ndc1_Nup PF09531.10 KXL41748.1 - 0.15 10.7 0.0 0.18 10.5 0.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MMR_HSR1_C PF08438.10 KXL41749.1 - 4.9e-36 123.7 0.0 7.9e-36 123.0 0.0 1.3 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 KXL41749.1 - 3.7e-16 59.2 0.0 9.1e-16 58.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXL41749.1 - 0.0025 17.4 0.0 0.025 14.1 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Ploopntkinase3 PF18751.1 KXL41749.1 - 0.0038 17.2 0.0 0.1 12.5 0.0 2.2 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 Dynamin_N PF00350.23 KXL41749.1 - 0.043 13.9 0.1 0.096 12.7 0.1 1.6 1 0 0 1 1 1 0 Dynamin family GTP_EFTU PF00009.27 KXL41749.1 - 0.066 12.7 0.0 13 5.2 0.0 2.5 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain KTI12 PF08433.10 KXL41749.1 - 0.067 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_28 PF13521.6 KXL41749.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXL41749.1 - 0.12 12.5 0.2 5.7 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KXL41749.1 - 0.12 12.2 0.0 20 5.0 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AIG1 PF04548.16 KXL41749.1 - 0.18 11.1 0.0 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 AIG1 family Syntaxin PF00804.25 KXL41751.1 - 4.5e-19 68.9 10.7 4.5e-19 68.9 10.7 1.6 1 1 1 2 2 2 1 Syntaxin SNARE PF05739.19 KXL41751.1 - 1e-11 44.6 0.0 2.4e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 SNARE domain Synaptobrevin PF00957.21 KXL41751.1 - 0.0013 18.4 0.5 0.004 16.9 0.5 1.8 1 0 0 1 1 1 1 Synaptobrevin Mod_r PF07200.13 KXL41751.1 - 0.0085 16.2 16.3 0.083 13.0 9.9 2.2 2 0 0 2 2 2 2 Modifier of rudimentary (Mod(r)) protein DUF2951 PF11166.8 KXL41751.1 - 0.12 12.6 0.2 0.12 12.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Allexi_40kDa PF05549.11 KXL41751.1 - 1.3 8.5 9.7 0.2 11.1 2.4 2.0 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF202 PF02656.15 KXL41752.1 - 1.7e-21 76.5 1.4 3.4e-21 75.4 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Apolipoprotein PF01442.18 KXL41756.1 - 0.00012 22.1 3.9 0.00022 21.2 3.9 1.4 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 KXL41756.1 - 0.042 13.9 0.3 0.099 12.7 0.3 1.5 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) OmpH PF03938.14 KXL41756.1 - 0.098 13.0 6.9 0.13 12.6 6.9 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) REF PF05755.12 KXL41756.1 - 0.15 11.8 1.1 0.48 10.2 1.1 1.7 1 1 0 1 1 1 0 Rubber elongation factor protein (REF) CDPS PF16715.5 KXL41756.1 - 0.29 10.8 1.2 0.88 9.2 0.8 1.8 1 1 1 2 2 2 0 Cyclodipeptide synthase DUF4407 PF14362.6 KXL41756.1 - 0.72 9.1 4.7 0.86 8.9 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF883 PF05957.13 KXL41756.1 - 2.7 8.6 14.1 0.6 10.7 7.1 2.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 KXL41756.1 - 4.5 7.9 15.3 0.21 12.2 1.7 2.8 1 1 1 2 2 2 0 YtxH-like protein Remorin_C PF03763.13 KXL41756.1 - 5.6 6.9 8.7 1.7 8.6 1.7 2.2 1 1 1 2 2 2 0 Remorin, C-terminal region Pex24p PF06398.11 KXL41757.1 - 0.00026 20.1 12.0 0.00061 18.9 12.0 1.6 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin CDT1_C PF16679.5 KXL41759.1 - 4.7e-20 71.8 0.2 1.3e-19 70.5 0.2 1.8 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain MnmE_helical PF12631.7 KXL41761.1 - 2e-30 106.5 0.0 5.3e-30 105.1 0.0 1.6 1 1 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 KXL41761.1 - 7.1e-23 81.1 0.0 1.8e-22 79.8 0.0 1.7 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 KXL41761.1 - 5.6e-19 68.3 0.1 1e-18 67.5 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KXL41761.1 - 1.5e-06 28.4 0.0 3.1e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 Dynamin family FeoB_N PF02421.18 KXL41761.1 - 1.7e-05 24.4 0.2 6.1e-05 22.6 0.2 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KXL41761.1 - 0.00082 19.3 1.0 0.077 12.9 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 KXL41761.1 - 0.041 14.4 0.0 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.27 KXL41761.1 - 0.047 13.2 0.0 9.5 5.7 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_28 PF13521.6 KXL41761.1 - 0.075 13.3 0.1 0.23 11.7 0.1 1.9 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KXL41761.1 - 0.081 13.1 0.1 2.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase F420_oxidored PF03807.17 KXL41761.1 - 0.14 12.7 1.0 5.2 7.7 0.5 2.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AAA_24 PF13479.6 KXL41761.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Glyco_hydro_3_C PF01915.22 KXL41761.1 - 0.18 11.7 0.2 0.43 10.5 0.1 1.5 1 1 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain CorA PF01544.18 KXL41761.1 - 0.37 10.1 1.0 0.64 9.3 1.0 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein F-box-like PF12937.7 KXL41762.1 - 0.00077 19.3 0.1 0.0044 16.9 0.0 2.3 2 0 0 2 2 2 1 F-box-like Hus1 PF04005.12 KXL41763.1 - 3.5e-93 311.9 0.0 3.9e-93 311.7 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein RNaseH_pPIWI_RE PF13032.6 KXL41763.1 - 0.013 15.5 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 RNaseH domain of pPIWI_RE FH2 PF02181.23 KXL41764.1 - 7.9e-88 295.1 2.2 1.7e-87 294.0 2.2 1.5 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_GBD PF06371.13 KXL41764.1 - 2.4e-65 219.6 0.0 6.5e-65 218.2 0.0 1.8 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 KXL41764.1 - 1.8e-50 171.3 7.0 2.8e-50 170.6 0.3 3.9 3 1 1 4 4 4 1 Diaphanous FH3 Domain Nrap_D6 PF17407.2 KXL41764.1 - 0.039 14.2 1.0 0.93 9.7 0.2 3.1 3 0 0 3 3 3 0 Nrap protein domain 6 DUF4065 PF13274.6 KXL41764.1 - 0.045 14.6 0.8 0.61 11.0 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4065) GATase_2 PF00310.21 KXL41770.1 - 1.3e-180 600.6 0.0 1.7e-180 600.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KXL41770.1 - 5.5e-157 522.6 0.0 9.1e-156 518.6 0.0 2.2 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KXL41770.1 - 2e-115 385.1 0.0 4.5e-113 377.4 0.0 2.4 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 KXL41770.1 - 1.3e-85 285.8 2.6 2.1e-85 285.1 2.6 1.3 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 KXL41770.1 - 1.1e-24 87.2 0.1 1.5e-23 83.5 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 KXL41770.1 - 5.7e-21 74.4 0.1 1.2e-20 73.3 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 KXL41770.1 - 1.2e-09 38.3 0.3 4.6e-09 36.4 0.0 2.2 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXL41770.1 - 8.8e-09 35.8 0.0 4.2e-05 24.0 0.1 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXL41770.1 - 1.9e-08 34.3 0.7 0.00084 19.0 0.1 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KXL41770.1 - 8e-08 32.0 0.0 1.9e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KXL41770.1 - 2.2e-06 27.1 0.4 0.0033 16.7 0.0 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXL41770.1 - 7.8e-06 24.8 0.1 1.7e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KXL41770.1 - 0.00012 21.3 0.2 0.00044 19.4 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain FMO-like PF00743.19 KXL41770.1 - 0.00029 19.4 0.2 0.018 13.5 0.0 2.7 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like FAD_oxidored PF12831.7 KXL41770.1 - 0.00033 20.1 0.0 0.00071 19.0 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXL41770.1 - 0.0007 18.9 0.0 0.0046 16.2 0.0 2.3 3 0 0 3 3 3 1 Thi4 family NAD_binding_7 PF13241.6 KXL41770.1 - 0.00094 19.6 1.0 0.75 10.3 0.1 2.8 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KXL41770.1 - 0.0012 18.2 0.0 0.0023 17.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FMN_dh PF01070.18 KXL41770.1 - 0.0025 16.9 0.8 0.024 13.7 0.9 2.3 3 0 0 3 3 3 1 FMN-dependent dehydrogenase AlaDh_PNT_C PF01262.21 KXL41770.1 - 0.0095 15.2 0.2 2.2 7.5 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 KXL41770.1 - 0.013 15.2 0.1 0.11 12.1 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 KXL41770.1 - 0.031 13.3 0.2 0.13 11.3 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein F420_oxidored PF03807.17 KXL41770.1 - 0.039 14.5 0.0 0.63 10.7 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 KXL41770.1 - 0.055 13.0 0.1 0.18 11.4 0.1 1.8 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 KXL41770.1 - 0.058 13.5 0.3 3.8 7.5 0.0 2.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KXL41770.1 - 0.1 12.0 0.4 0.25 10.7 0.0 1.8 2 0 0 2 2 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KXL41770.1 - 0.11 12.5 0.0 0.3 11.0 0.0 1.8 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.22 KXL41770.1 - 0.12 11.4 1.9 0.18 10.8 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 KXL41770.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KXL41770.1 - 0.18 11.9 0.0 28 4.8 0.0 2.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Peptidase_M24 PF00557.24 KXL41771.1 - 4.7e-21 75.5 0.0 5.6e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 WW PF00397.26 KXL41772.1 - 1.3e-09 37.9 8.7 3e-09 36.8 8.7 1.7 1 0 0 1 1 1 1 WW domain Mito_carr PF00153.27 KXL41773.1 - 2.8e-29 100.9 2.5 2.6e-14 52.9 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein NDUF_B12 PF08122.12 KXL41773.1 - 0.56 10.3 2.4 0.89 9.6 0.1 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family SNRNP27 PF08648.12 KXL41774.1 - 6.7e-24 83.7 0.5 1.1e-23 83.1 0.5 1.3 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins Elong_Iki1 PF10483.9 KXL41775.1 - 3.6e-93 312.3 0.0 4.1e-93 312.1 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 NACHT PF05729.12 KXL41775.1 - 0.069 13.1 1.1 0.24 11.3 0.2 2.1 1 1 1 2 2 2 0 NACHT domain ASXH PF13919.6 KXL41776.1 - 8.5e-15 55.0 0.0 1.4e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Asx homology domain Longin PF13774.6 KXL41777.1 - 5.3e-22 77.7 0.1 8.5e-22 77.0 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KXL41777.1 - 1e-15 57.3 0.1 2.1e-15 56.3 0.0 1.5 2 0 0 2 2 2 1 Synaptobrevin DUF4404 PF14357.6 KXL41777.1 - 0.021 15.4 0.8 2.1 9.1 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Chorismate_bind PF00425.18 KXL41779.1 - 7.6e-75 251.8 0.0 1.1e-74 251.3 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 KXL41779.1 - 4.6e-27 95.0 0.0 1e-26 93.9 0.0 1.6 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 KXL41779.1 - 8.4e-19 68.2 0.0 1.7e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 KXL41779.1 - 6e-05 22.9 0.0 0.00028 20.7 0.0 2.1 1 1 0 1 1 1 1 Peptidase C26 adh_short PF00106.25 KXL41780.1 - 3.1e-25 88.8 0.0 8.7e-25 87.3 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL41780.1 - 1.4e-19 70.6 0.0 2.2e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL41780.1 - 0.028 14.3 0.0 0.094 12.6 0.0 1.8 2 1 0 2 2 2 0 KR domain Fungal_trans PF04082.18 KXL41781.1 - 4.5e-13 48.8 3.0 7.2e-13 48.2 3.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL41781.1 - 8e-09 35.5 16.7 1.9e-08 34.2 16.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med6 PF04934.14 KXL41782.1 - 1.8e-25 89.3 0.0 2.9e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component DUF4698 PF15769.5 KXL41782.1 - 0.0022 17.2 2.6 0.0033 16.5 2.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4698) RR_TM4-6 PF06459.12 KXL41782.1 - 0.54 10.0 5.2 0.72 9.6 5.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Rtf2 PF04641.12 KXL41782.1 - 0.76 9.1 5.7 1.2 8.5 5.7 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger CENP-U PF13097.6 KXL41782.1 - 8.3 6.3 12.6 15 5.5 12.6 1.3 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit adh_short_C2 PF13561.6 KXL41784.1 - 9.1e-32 110.5 0.1 1.2e-31 110.1 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL41784.1 - 6.9e-20 71.3 0.1 1.2e-19 70.6 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase CMD PF02627.20 KXL41785.1 - 0.0022 18.0 0.1 0.0033 17.4 0.0 1.5 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Fungal_trans PF04082.18 KXL41786.1 - 2.1e-15 56.5 0.0 3.7e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain BTB PF00651.31 KXL41787.1 - 1.8e-07 31.4 0.0 5.9e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Lys-AminoMut_A PF09043.11 KXL41787.1 - 0.16 10.4 0.0 0.19 10.1 0.0 1.1 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit RF-1 PF00472.20 KXL41788.1 - 2.7e-26 91.8 6.4 4e-26 91.2 6.4 1.2 1 0 0 1 1 1 1 RF-1 domain Aminopep PF10023.9 KXL41788.1 - 0.13 11.6 6.4 0.17 11.2 6.4 1.1 1 0 0 1 1 1 0 Putative aminopeptidase C_Hendra PF16821.5 KXL41788.1 - 0.24 11.3 5.1 0.073 13.0 2.0 1.7 1 1 1 2 2 2 0 C protein from hendra and measles viruses SPT_ssu-like PF11779.8 KXL41789.1 - 4.4e-24 83.9 3.2 4.4e-24 83.9 3.2 1.7 2 0 0 2 2 2 1 Small subunit of serine palmitoyltransferase-like CRT10 PF08728.10 KXL41790.1 - 9.1e-09 34.1 0.0 0.00023 19.5 0.0 2.3 2 0 0 2 2 2 2 CRT10 DUF1640 PF07798.11 KXL41794.1 - 1.7e-44 152.0 7.4 2.1e-44 151.6 7.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF4407 PF14362.6 KXL41794.1 - 0.066 12.6 4.7 0.1 11.9 4.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) PIF2 PF04631.12 KXL41794.1 - 0.088 11.6 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Per os infectivity factor 2 DUF3782 PF12644.7 KXL41794.1 - 0.49 10.6 4.7 0.96 9.6 3.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3782) Fungal_TACC PF12709.7 KXL41794.1 - 0.82 10.2 5.8 0.75 10.3 1.6 2.5 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins EMC3_TMCO1 PF01956.16 KXL41794.1 - 1.3 8.7 4.2 38 3.9 0.0 2.2 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like OmpH PF03938.14 KXL41794.1 - 2.4 8.5 10.9 0.21 11.9 6.4 1.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) NmrA PF05368.13 KXL41795.1 - 5e-30 104.8 0.0 7.1e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXL41795.1 - 2.4e-11 43.8 0.0 7.3e-11 42.3 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXL41795.1 - 5.8e-08 32.5 0.1 7e-06 25.7 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXL41795.1 - 1.2e-05 24.5 0.0 1.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KXL41795.1 - 3.8e-05 24.1 0.0 8.7e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 KXL41795.1 - 5.1e-05 23.3 0.0 8.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KXL41795.1 - 7.7e-05 23.0 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 KXL41795.1 - 0.021 14.3 0.1 0.03 13.7 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DapB_N PF01113.20 KXL41795.1 - 0.031 14.4 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 KXL41795.1 - 0.062 12.7 0.0 0.098 12.1 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KXL41795.1 - 0.065 12.3 0.1 0.096 11.8 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Aldo_ket_red PF00248.21 KXL41796.1 - 6.7e-33 114.1 0.1 6.2e-26 91.3 0.0 2.1 1 1 1 2 2 2 2 Aldo/keto reductase family 2-Hacid_dh_C PF02826.19 KXL41796.1 - 0.07 12.5 0.7 25 4.2 0.1 3.0 2 1 1 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ribosomal_S5 PF00333.20 KXL41796.1 - 8.9 6.4 6.6 12 6.0 3.2 2.7 2 1 0 2 2 2 0 Ribosomal protein S5, N-terminal domain Glyco_hydro_61 PF03443.14 KXL41797.1 - 1.2e-64 218.1 0.1 1.4e-64 217.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Gp_dh_C PF02800.20 KXL41798.1 - 1.3e-70 236.1 0.1 1.8e-70 235.6 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KXL41798.1 - 1.8e-38 130.9 0.2 4.8e-38 129.6 0.1 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 KXL41798.1 - 0.012 15.7 1.2 0.035 14.2 0.3 2.3 2 1 1 3 3 3 0 Dihydrodipicolinate reductase, N-terminus Glyco_hydro_76 PF03663.14 KXL41800.1 - 1.9e-149 498.2 21.1 2.3e-149 497.9 21.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KXL41800.1 - 0.0077 15.3 15.9 0.011 14.9 1.8 3.1 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 eIF-6 PF01912.18 KXL41801.1 - 5.3e-79 264.2 0.3 8.9e-79 263.5 0.2 1.4 2 0 0 2 2 2 1 eIF-6 family PUF PF00806.19 KXL41802.1 - 1.3e-64 210.4 5.2 2.1e-09 36.6 0.0 8.2 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat sCache_2 PF17200.4 KXL41802.1 - 0.013 15.3 0.1 8.4 6.2 0.0 3.5 3 1 1 4 4 4 0 Single Cache domain 2 TBPIP PF07106.13 KXL41802.1 - 0.017 15.0 0.2 24 4.9 0.0 4.0 4 0 0 4 4 4 0 TBPIP/Hop2 winged helix domain RNA_pol_Rpb1_3 PF04983.18 KXL41802.1 - 0.11 12.5 0.3 9.4 6.2 0.2 2.5 2 1 0 2 2 2 0 RNA polymerase Rpb1, domain 3 UQ_con PF00179.26 KXL41803.1 - 2.6e-34 117.9 0.0 3e-34 117.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXL41803.1 - 0.00035 20.3 0.0 0.00039 20.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KXL41803.1 - 0.0014 18.9 0.1 0.0021 18.3 0.1 1.2 1 0 0 1 1 1 1 RWD domain UFC1 PF08694.11 KXL41803.1 - 0.031 13.9 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Prok-E2_E PF14462.6 KXL41803.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family E Glyco_hydro_63 PF03200.16 KXL41804.1 - 6e-165 549.7 0.2 7.3e-164 546.1 0.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KXL41804.1 - 2.1e-78 263.5 0.0 1.7e-77 260.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 KXL41804.1 - 0.00015 20.7 0.2 0.00025 20.0 0.2 1.2 1 0 0 1 1 1 1 Trehalase MMtag PF10159.9 KXL41805.1 - 1.7e-30 105.1 1.9 1.7e-30 105.1 1.9 2.7 2 1 0 2 2 2 1 Multiple myeloma tumor-associated PS_Dcarbxylase PF02666.15 KXL41806.1 - 4.6e-52 176.5 0.0 6.9e-52 175.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase DUF220 PF02713.14 KXL41806.1 - 0.068 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF220 PSD4 PF07631.11 KXL41806.1 - 0.18 12.3 0.4 0.38 11.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1592) Myb_DNA-binding PF00249.31 KXL41807.1 - 7.2e-12 45.3 1.0 4.5e-11 42.8 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXL41807.1 - 7.1e-07 29.4 0.3 2.7e-06 27.5 0.2 1.9 1 1 1 2 2 2 1 Myb-like DNA-binding domain CAP_GLY PF01302.25 KXL41809.1 - 5.6e-24 84.0 0.0 8e-24 83.4 0.0 1.2 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 KXL41809.1 - 2.5e-19 69.5 0.0 3.8e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 KXL41809.1 - 6.7e-05 22.6 0.0 0.0002 21.0 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family Mif2_N PF15624.6 KXL41810.1 - 1.6e-30 106.5 4.8 1.6e-30 106.5 4.8 3.0 2 1 0 2 2 2 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.8 KXL41810.1 - 1.9e-17 63.3 1.3 3.9e-17 62.2 1.3 1.6 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 KXL41810.1 - 0.09 12.5 0.1 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 Cupin domain Cupin_3 PF05899.12 KXL41810.1 - 0.1 12.3 0.2 0.27 10.9 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF861) RNase_HII PF01351.18 KXL41812.1 - 5.4e-50 170.0 0.0 6.8e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII Rap_GAP PF02145.15 KXL41813.1 - 2.2e-42 144.7 0.0 3.7e-42 144.0 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 KXL41813.1 - 4.3e-29 101.7 3.5 8.9e-27 94.1 0.1 3.2 3 0 0 3 3 3 2 Tuberin DUF3384 PF11864.8 KXL41813.1 - 1.9e-18 66.6 1.5 4.5e-18 65.4 1.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Peptidase_S66 PF02016.15 KXL41813.1 - 0.017 15.2 0.0 0.044 13.9 0.0 1.7 1 0 0 1 1 1 0 LD-carboxypeptidase N-terminal domain NUT PF12881.7 KXL41813.1 - 0.057 11.9 0.3 0.087 11.2 0.3 1.2 1 0 0 1 1 1 0 NUT protein TRAPPC9-Trs120 PF08626.11 KXL41814.1 - 1.1e-189 632.6 0.0 2.4e-173 578.4 0.0 3.8 2 1 1 3 3 3 3 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Glyco_hydro_61 PF03443.14 KXL41815.1 - 5.1e-66 222.5 0.0 6.2e-66 222.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 VTC PF09359.10 KXL41816.1 - 1.5e-88 296.8 1.5 1.5e-88 296.8 1.5 1.5 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 KXL41816.1 - 2e-13 50.5 6.0 4.9e-13 49.3 6.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 KXL41816.1 - 1.7e-06 28.3 17.2 3.2e-06 27.3 1.9 3.9 2 2 2 4 4 4 2 SPX domain NUDIX PF00293.28 KXL41817.1 - 2.7e-12 46.9 0.1 6.3e-12 45.7 0.1 1.6 1 1 0 1 1 1 1 NUDIX domain FMN_dh PF01070.18 KXL41818.1 - 6.4e-107 357.6 0.0 9.3e-107 357.0 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KXL41818.1 - 1.4e-17 63.6 0.0 2.9e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KXL41818.1 - 8.9e-06 25.1 0.0 1.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KXL41818.1 - 1.3e-05 24.3 0.1 0.0014 17.7 0.1 2.5 2 1 1 3 3 3 2 IMP dehydrogenase / GMP reductase domain ATP11 PF06644.11 KXL41818.1 - 0.0018 18.2 0.0 0.0029 17.5 0.0 1.2 1 0 0 1 1 1 1 ATP11 protein Ssl1 PF04056.14 KXL41819.1 - 3.6e-71 239.0 0.0 4.7e-71 238.6 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 KXL41819.1 - 1.5e-19 69.9 10.1 1.5e-19 69.9 10.1 2.9 2 2 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 KXL41819.1 - 3.6e-14 53.3 0.0 6.7e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.14 KXL41819.1 - 0.00093 18.8 1.1 0.0015 18.1 1.1 1.3 1 0 0 1 1 1 1 Transcription factor Tfb4 VWA PF00092.28 KXL41819.1 - 0.0039 17.5 0.0 0.013 15.8 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain Ras PF00071.22 KXL41820.1 - 1.3e-62 210.2 0.2 1.5e-62 210.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXL41820.1 - 1.6e-35 121.9 0.3 2.3e-35 121.4 0.3 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXL41820.1 - 3.6e-13 49.3 0.1 4.4e-13 49.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXL41820.1 - 7.3e-08 32.5 0.1 1.1e-07 32.0 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXL41820.1 - 2.3e-05 24.4 0.1 0.015 15.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KXL41820.1 - 0.00053 19.6 0.1 0.0019 17.8 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KXL41820.1 - 0.00061 19.2 0.0 0.00073 19.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 KXL41820.1 - 0.0022 18.3 0.0 0.017 15.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 KXL41820.1 - 0.0067 15.9 0.0 0.013 15.0 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 KXL41820.1 - 0.01 15.9 0.1 0.025 14.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXL41820.1 - 0.014 15.8 0.2 0.038 14.4 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KXL41820.1 - 0.014 15.9 0.1 0.02 15.4 0.1 1.4 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 KXL41820.1 - 0.021 14.6 0.1 0.047 13.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KXL41820.1 - 0.03 13.7 0.0 0.16 11.4 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein FeoB_N PF02421.18 KXL41820.1 - 0.036 13.6 0.1 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF1128 PF06569.11 KXL41820.1 - 0.039 13.9 0.0 0.098 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) SpoIIID PF12116.8 KXL41820.1 - 0.073 13.2 0.1 1.8 8.7 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D MCM PF00493.23 KXL41820.1 - 0.11 11.6 0.0 0.2 10.7 0.0 1.5 1 1 0 1 1 1 0 MCM P-loop domain AAA_21 PF13304.6 KXL41820.1 - 0.11 12.3 0.6 0.17 11.7 0.5 1.5 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 KXL41820.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region BC10 PF06726.12 KXL41821.1 - 4.6e-14 52.4 7.5 7.5e-14 51.7 7.5 1.3 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 DUF4113 PF13438.6 KXL41821.1 - 0.0042 17.1 0.0 0.0092 16.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4113) VKOR PF07884.14 KXL41821.1 - 0.4 10.9 7.4 0.62 10.3 7.4 1.3 1 0 0 1 1 1 0 Vitamin K epoxide reductase family ERAP1_C PF11838.8 KXL41822.1 - 1.7e-88 297.2 0.1 4.3e-88 295.9 0.1 1.7 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KXL41822.1 - 2e-83 279.3 4.3 4.3e-83 278.2 4.3 1.6 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KXL41822.1 - 2.9e-45 154.7 1.1 6.3e-45 153.6 1.1 1.6 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain MATalpha_HMGbox PF04769.12 KXL41822.1 - 0.038 13.3 0.1 0.075 12.3 0.1 1.4 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box WD40 PF00400.32 KXL41823.1 - 7.5e-17 61.4 5.5 0.026 15.4 0.0 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat Myb_DNA-bind_6 PF13921.6 KXL41823.1 - 4.7e-09 36.4 0.0 4e-05 23.8 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KXL41823.1 - 2e-07 31.1 0.0 0.0023 18.1 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain ANAPC4_WD40 PF12894.7 KXL41823.1 - 3.3e-07 30.5 0.0 0.14 12.5 0.0 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KXL41823.1 - 0.023 14.7 0.0 1.8 8.6 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KXL41823.1 - 0.15 11.0 0.0 2.1 7.2 0.0 2.8 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein AA_permease_2 PF13520.6 KXL41824.1 - 5.3e-59 200.1 54.9 6.3e-59 199.9 54.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXL41824.1 - 1.5e-28 99.7 47.7 2e-28 99.3 47.7 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3493 PF11998.8 KXL41824.1 - 0.61 10.3 0.0 0.61 10.3 0.0 2.7 3 0 0 3 3 3 0 Low psii accumulation1 / Rep27 Coprogen_oxidas PF01218.18 KXL41825.1 - 3.2e-144 479.1 0.0 4.1e-144 478.8 0.0 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase DUF1651 PF07864.11 KXL41825.1 - 0.073 13.4 0.0 0.27 11.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1651) WD40 PF00400.32 KXL41826.1 - 3.3e-18 65.7 2.8 0.0024 18.7 0.1 6.6 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL41826.1 - 3.3e-06 27.3 0.6 0.0092 16.3 0.1 4.2 2 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXL41826.1 - 7.6e-05 21.5 1.0 0.14 10.8 0.1 3.2 1 1 1 3 3 3 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KXL41826.1 - 0.033 13.5 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain NusG_II PF07009.11 KXL41826.1 - 0.074 13.3 0.2 13 6.0 0.0 3.0 2 1 1 3 3 3 0 NusG domain II Sigma70_r1_2 PF00140.20 KXL41826.1 - 0.076 13.0 5.9 0.084 12.9 4.0 2.1 2 0 0 2 2 2 0 Sigma-70 factor, region 1.2 Aconitase PF00330.20 KXL41827.1 - 4.3e-110 368.9 0.0 3.8e-109 365.7 0.0 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KXL41827.1 - 8.1e-26 90.9 0.0 1.5e-25 90.0 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF5068 PF16781.5 KXL41827.1 - 0.16 11.7 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5068) Aminotran_5 PF00266.19 KXL41828.1 - 1.3e-22 80.3 0.0 5.8e-13 48.5 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Mso1_Sec1_bdg PF14475.6 KXL41829.1 - 1.7e-18 65.9 0.1 3.3e-18 65.0 0.1 1.5 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Phage_Nu1 PF07471.12 KXL41830.1 - 0.04 13.7 0.2 0.052 13.3 0.2 1.1 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 PTRF_SDPR PF15237.6 KXL41830.1 - 0.041 13.5 0.7 0.05 13.2 0.7 1.1 1 0 0 1 1 1 0 PTRF/SDPR family 2-Hacid_dh_C PF02826.19 KXL41831.1 - 1.3e-49 167.9 0.0 2e-49 167.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXL41831.1 - 2e-16 59.9 0.0 2.8e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXL41831.1 - 0.0014 18.8 0.0 0.0042 17.3 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 KXL41831.1 - 0.003 16.9 0.0 0.51 9.6 0.0 2.3 1 1 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.16 KXL41832.1 - 1.9e-29 102.7 25.7 2.3e-29 102.4 25.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KXL41832.1 - 0.0059 15.5 7.3 0.0096 14.8 7.3 1.4 1 1 0 1 1 1 1 MFS_1 like family zf_CCCH_4 PF18345.1 KXL41833.1 - 0.095 12.8 0.4 0.095 12.8 0.4 4.2 4 0 0 4 4 4 0 Zinc finger domain DcpS_C PF11969.8 KXL41834.1 - 7.5e-16 58.6 2.1 1e-14 54.9 2.1 2.2 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding zf-C2HE PF16278.5 KXL41834.1 - 2.1e-14 53.7 0.6 5.1e-14 52.5 0.6 1.7 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger HIT PF01230.23 KXL41834.1 - 4.4e-14 53.0 0.3 1.4e-13 51.3 0.3 1.8 1 1 0 1 1 1 1 HIT domain DUF4211 PF13926.6 KXL41835.1 - 1.3e-40 138.8 0.4 3.8e-40 137.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) Fasciclin PF02469.22 KXL41836.1 - 6.1e-45 152.6 5.5 1.2e-27 96.6 0.7 2.3 2 0 0 2 2 2 2 Fasciclin domain Thioredoxin_13 PF18401.1 KXL41836.1 - 0.018 15.0 0.6 0.046 13.6 0.6 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain DUF211 PF02680.14 KXL41836.1 - 0.21 11.8 1.3 11 6.3 0.1 2.8 2 0 0 2 2 2 0 Uncharacterized ArCR, COG1888 Ras PF00071.22 KXL41837.1 - 3.1e-55 186.2 0.0 4.1e-55 185.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXL41837.1 - 8.6e-32 109.9 0.0 1.4e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXL41837.1 - 3.5e-11 42.9 0.0 4e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXL41837.1 - 4.2e-07 30.1 0.0 6e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KXL41837.1 - 5.3e-06 25.9 0.0 6.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KXL41837.1 - 9.4e-05 22.4 0.0 0.0055 16.6 0.1 2.4 1 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KXL41837.1 - 0.00014 21.4 0.0 0.0059 16.2 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KXL41837.1 - 0.00095 19.0 0.2 0.015 15.0 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.10 KXL41837.1 - 0.0077 15.7 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit cobW PF02492.19 KXL41837.1 - 0.0081 15.8 0.0 0.033 13.8 0.0 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 KXL41837.1 - 0.013 15.8 0.0 0.021 15.2 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KXL41837.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KXL41837.1 - 0.022 15.0 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 KXL41837.1 - 0.023 14.0 0.0 0.045 13.0 0.0 1.5 1 0 0 1 1 1 0 Septin AAA_5 PF07728.14 KXL41837.1 - 0.027 14.5 0.0 0.054 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 KXL41837.1 - 0.034 13.9 0.0 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 KXL41837.1 - 0.035 13.6 0.1 0.058 12.9 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 KXL41837.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 KXL41837.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein ATPase_2 PF01637.18 KXL41837.1 - 0.14 12.0 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea EXOSC1 PF10447.9 KXL41838.1 - 5e-18 65.7 0.9 2.9e-12 47.2 0.1 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 KXL41838.1 - 9.5e-10 38.1 0.3 2.2e-09 37.0 0.3 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Rrp40_N PF18311.1 KXL41838.1 - 0.68 9.9 4.0 3.8 7.5 1.6 2.4 2 0 0 2 2 2 0 Exosome complex exonuclease Rrp40 N-terminal domain HSBP1 PF06825.12 KXL41839.1 - 6.1e-20 70.8 0.8 9.9e-20 70.1 0.8 1.4 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Laminin_I PF06008.14 KXL41839.1 - 0.0069 16.1 0.5 0.0084 15.8 0.5 1.0 1 0 0 1 1 1 1 Laminin Domain I CLZ PF16526.5 KXL41839.1 - 0.0077 16.6 0.2 0.0099 16.2 0.2 1.2 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Matrilin_ccoil PF10393.9 KXL41839.1 - 0.0077 16.1 0.1 0.019 14.8 0.0 1.7 2 1 0 2 2 2 1 Trimeric coiled-coil oligomerisation domain of matrilin NPV_P10 PF05531.12 KXL41839.1 - 0.022 15.2 1.4 0.14 12.6 1.4 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 KXL41839.1 - 0.024 14.7 0.4 0.028 14.5 0.4 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4226 PF10774.9 KXL41839.1 - 0.052 13.8 0.2 0.066 13.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) Trimer_CC PF08954.11 KXL41839.1 - 0.073 12.6 0.2 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 Trimerisation motif DELLA PF12041.8 KXL41839.1 - 0.087 12.7 0.5 6.5 6.7 0.1 2.2 2 1 0 2 2 2 0 Transcriptional regulator DELLA protein N terminal XhlA PF10779.9 KXL41839.1 - 0.091 13.0 0.8 14 6.0 0.1 2.1 2 0 0 2 2 2 0 Haemolysin XhlA DUF1707 PF08044.11 KXL41839.1 - 0.1 12.7 0.6 0.64 10.1 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) Laminin_II PF06009.12 KXL41839.1 - 0.13 12.3 1.3 0.3 11.1 1.3 1.6 1 1 0 1 1 1 0 Laminin Domain II Ebp2 PF05890.12 KXL41840.1 - 1.9e-92 309.6 6.4 1.9e-92 309.6 6.4 2.2 2 1 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Asp4 PF16996.5 KXL41840.1 - 0.12 12.2 0.2 0.45 10.3 0.2 2.0 1 0 0 1 1 1 0 Accessory secretory protein Sec Asp4 Abhydrolase_1 PF00561.20 KXL41841.1 - 3e-06 27.1 0.0 4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold TauD PF02668.16 KXL41844.1 - 6.4e-52 177.0 0.1 8.4e-52 176.6 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Fn3-like PF14310.6 KXL41844.1 - 0.12 12.5 0.2 0.25 11.5 0.2 1.5 1 0 0 1 1 1 0 Fibronectin type III-like domain tRNA_m1G_MT PF01746.21 KXL41845.1 - 6.9e-27 94.4 0.0 2.3e-24 86.2 0.0 2.2 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Peptidase_M3 PF01432.20 KXL41846.1 - 8.6e-123 411.0 0.0 1.3e-122 410.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 KXL41846.1 - 0.022 14.4 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase M50B-like Peptidase_M91 PF14891.6 KXL41846.1 - 0.12 12.7 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 Effector protein DUF1643 PF07799.12 KXL41846.1 - 0.14 12.3 0.0 0.42 10.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1643) Fungal_trans PF04082.18 KXL41847.1 - 1.2e-10 40.9 0.3 5.6e-10 38.7 0.0 1.9 2 1 1 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL41847.1 - 1.4e-08 34.7 8.0 2.4e-08 33.9 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldolase_II PF00596.21 KXL41848.1 - 8e-27 94.4 0.1 1e-26 94.0 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain ABM PF03992.16 KXL41849.1 - 0.02 15.0 0.0 0.083 13.0 0.0 2.0 3 0 0 3 3 3 0 Antibiotic biosynthesis monooxygenase PAS_9 PF13426.7 KXL41851.1 - 1.9e-24 85.9 0.0 1e-14 54.6 0.0 3.4 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 KXL41851.1 - 5.7e-15 55.4 0.0 5.8e-09 36.1 0.0 3.6 3 0 0 3 3 3 3 PAS fold GATA PF00320.27 KXL41851.1 - 2.2e-14 52.8 6.7 4.8e-14 51.7 6.7 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.25 KXL41851.1 - 8.9e-12 45.0 0.0 1.7e-05 24.8 0.0 3.7 3 1 0 3 3 3 2 PAS fold PAS_11 PF14598.6 KXL41851.1 - 3.1e-07 30.5 0.0 0.019 15.1 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 KXL41851.1 - 6.7e-05 23.1 0.0 0.27 11.5 0.0 3.0 3 0 0 3 3 3 2 PAS fold PAS_2 PF08446.11 KXL41851.1 - 0.0043 17.7 0.0 1.8 9.3 0.0 3.5 3 0 0 3 3 3 1 PAS fold Ras PF00071.22 KXL41852.1 - 4.8e-39 133.6 0.0 6.4e-39 133.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXL41852.1 - 1.1e-13 51.4 0.0 1.9e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXL41852.1 - 9.3e-06 25.2 0.0 1.2e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXL41852.1 - 0.0003 20.8 0.0 0.00049 20.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXL41852.1 - 0.00068 19.2 0.0 0.013 15.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PRK PF00485.18 KXL41852.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 KXL41852.1 - 0.1 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain DUF2510 PF10708.9 KXL41852.1 - 2.3 8.1 8.7 0.35 10.7 3.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2510) GRIM-19 PF06212.12 KXL41853.1 - 1.2e-22 80.3 0.3 3.5e-22 78.8 0.3 1.6 1 1 0 1 1 1 1 GRIM-19 protein ApoO PF09769.9 KXL41854.1 - 1.5e-39 135.0 0.1 3e-39 133.9 0.0 1.5 2 0 0 2 2 2 1 Apolipoprotein O DUF1304 PF06993.12 KXL41854.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) MFS_1 PF07690.16 KXL41855.1 - 1.3e-14 54.0 42.9 1.1e-09 37.7 18.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL41856.1 - 2.3e-80 270.7 21.6 2.7e-80 270.5 21.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL41856.1 - 1.7e-17 63.4 47.5 1.8e-15 56.8 25.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 KXL41857.1 - 9.2e-13 47.8 0.3 1.2e-12 47.4 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL41857.1 - 4.9e-06 26.6 5.4 7.8e-06 25.9 5.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box PF00646.33 KXL41858.1 - 0.00018 21.3 0.3 0.0005 19.9 0.3 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXL41858.1 - 0.0038 17.1 0.9 0.011 15.6 0.5 2.0 2 0 0 2 2 2 1 F-box-like Mito_carr PF00153.27 KXL41860.1 - 1.3e-59 198.1 5.4 2.4e-19 69.1 1.5 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein Peroxin-3 PF04882.12 KXL41860.1 - 6.6 5.6 6.7 9.4 5.1 6.7 1.1 1 0 0 1 1 1 0 Peroxin-3 TPR_2 PF07719.17 KXL41862.1 - 2.5e-10 39.6 3.8 0.0016 18.4 0.1 4.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXL41862.1 - 1.6e-09 37.2 2.3 0.0075 16.1 0.4 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXL41862.1 - 5e-09 35.7 2.2 0.0027 17.8 0.0 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXL41862.1 - 9.2e-08 31.7 4.4 0.05 13.3 0.0 4.4 2 1 2 4 4 4 3 TPR repeat TPR_12 PF13424.6 KXL41862.1 - 3.8e-07 30.3 2.5 2e-05 24.8 0.3 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXL41862.1 - 1.7e-06 28.0 0.3 0.032 14.6 0.3 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXL41862.1 - 0.002 18.7 0.7 0.002 18.7 0.7 4.0 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXL41862.1 - 0.01 16.3 4.4 0.13 12.8 0.1 3.7 2 1 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KXL41862.1 - 0.021 15.1 1.0 0.051 13.8 1.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KXL41862.1 - 0.076 13.2 0.1 0.076 13.2 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXL41862.1 - 0.17 11.8 3.7 11 6.1 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXL41862.1 - 0.29 12.1 17.2 1.5 9.8 0.2 5.8 5 2 2 7 7 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXL41862.1 - 1.2 9.3 8.0 7.1 6.9 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Hydrolase PF00702.26 KXL41863.1 - 2.6e-05 24.6 0.0 0.00012 22.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXL41863.1 - 0.0073 16.4 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Sugar_tr PF00083.24 KXL41864.1 - 4.6e-55 187.3 29.5 5.4e-55 187.0 29.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL41864.1 - 4.1e-15 55.6 22.5 4.1e-15 55.6 22.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 KXL41864.1 - 0.0025 16.4 3.9 0.0025 16.4 3.9 3.2 3 1 1 4 4 4 2 MFS/sugar transport protein MFS_1_like PF12832.7 KXL41864.1 - 0.096 11.5 16.5 0.034 13.0 5.7 2.7 2 1 1 3 3 3 0 MFS_1 like family Aldo_ket_red PF00248.21 KXL41865.1 - 0.00047 19.5 0.0 0.00052 19.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TPR_1 PF00515.28 KXL41866.1 - 3.3e-45 150.1 22.5 2e-10 40.0 0.1 9.3 8 1 1 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 KXL41866.1 - 3e-40 133.1 20.7 9.7e-08 31.6 0.1 9.2 8 1 1 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.6 KXL41866.1 - 5e-28 96.5 22.4 9.7e-08 31.6 2.5 7.7 6 2 2 8 8 7 6 TPR repeat DnaJ PF00226.31 KXL41866.1 - 1.6e-27 95.4 3.2 7.6e-27 93.2 3.2 2.3 1 0 0 1 1 1 1 DnaJ domain TPR_19 PF14559.6 KXL41866.1 - 7e-26 90.5 19.6 1.6e-07 31.8 0.5 6.3 3 3 4 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.6 KXL41866.1 - 2.1e-25 89.1 7.0 4.3e-06 27.3 0.2 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 KXL41866.1 - 1.2e-21 75.6 11.6 9.7e-06 26.0 0.1 8.2 4 3 4 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 KXL41866.1 - 1.5e-21 74.7 17.9 0.00066 19.7 0.0 9.1 8 1 1 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.6 KXL41866.1 - 1.3e-18 67.0 18.6 3.2e-05 24.1 0.9 6.7 3 3 3 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXL41866.1 - 4.5e-17 60.7 12.0 0.065 13.3 0.0 8.2 7 1 0 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 KXL41866.1 - 3.6e-16 58.3 21.2 0.0037 17.5 0.2 7.7 9 0 0 9 9 6 5 Tetratricopeptide repeat TPR_9 PF13371.6 KXL41866.1 - 1.5e-13 50.6 13.0 1.4e-05 25.1 0.0 5.6 5 2 1 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXL41866.1 - 7.4e-13 48.5 12.0 3.5e-05 24.0 2.5 4.0 3 2 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KXL41866.1 - 2.1e-11 43.7 21.7 0.027 15.1 0.2 8.2 8 1 1 9 9 8 4 Tetratricopeptide repeat TPR_15 PF13429.6 KXL41866.1 - 4e-09 36.1 10.6 0.016 14.5 0.5 4.2 3 2 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 KXL41866.1 - 1.1e-08 34.6 17.1 0.31 11.0 0.2 7.7 8 0 0 8 8 7 3 Tetratricopeptide repeat BTAD PF03704.17 KXL41866.1 - 2.7e-07 31.1 10.3 0.063 13.7 0.1 4.9 2 2 2 4 4 4 3 Bacterial transcriptional activator domain TPR_MalT PF17874.1 KXL41866.1 - 3.4e-06 26.7 4.3 0.21 10.9 0.1 3.9 2 1 2 4 4 4 3 MalT-like TPR region TPR_4 PF07721.14 KXL41866.1 - 8.1e-06 26.0 5.5 0.079 13.6 0.1 4.3 4 0 0 4 4 3 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KXL41866.1 - 2.4e-05 24.8 2.7 1.5 9.3 0.7 4.4 2 2 1 3 3 3 2 Alkyl sulfatase dimerisation TPR_20 PF14561.6 KXL41866.1 - 0.00027 21.2 11.8 0.28 11.5 0.1 5.1 3 2 1 4 4 4 2 Tetratricopeptide repeat FAT PF02259.23 KXL41866.1 - 0.0004 19.7 1.6 0.0066 15.7 0.1 2.6 1 1 0 2 2 2 1 FAT domain PPR PF01535.20 KXL41866.1 - 0.0032 17.6 0.3 5.3 7.5 0.0 4.4 4 1 1 5 5 2 0 PPR repeat Fis1_TPR_C PF14853.6 KXL41866.1 - 0.017 15.2 12.7 4.3 7.5 0.1 5.6 5 1 1 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat SHNi-TPR PF10516.9 KXL41866.1 - 0.037 13.5 7.5 0.84 9.1 0.1 5.1 6 0 0 6 6 6 0 SHNi-TPR DUF928 PF06051.12 KXL41866.1 - 0.06 13.2 3.2 1.4 8.8 0.2 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF928) DUF3597 PF12200.8 KXL41866.1 - 0.062 13.8 0.1 0.062 13.8 0.1 3.4 4 0 0 4 4 2 0 Domain of unknown function (DUF3597) MIT PF04212.18 KXL41866.1 - 0.068 13.3 13.6 19 5.4 2.7 5.8 3 3 1 5 5 5 0 MIT (microtubule interacting and transport) domain Coatomer_E PF04733.14 KXL41866.1 - 0.069 12.6 2.0 3.1 7.1 0.2 2.9 2 1 0 3 3 3 0 Coatomer epsilon subunit ChAPs PF09295.10 KXL41866.1 - 0.096 11.7 2.5 0.16 11.0 0.4 2.0 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF4192 PF13830.6 KXL41866.1 - 0.16 12.0 4.6 0.12 12.5 0.9 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4192) DUF3856 PF12968.7 KXL41866.1 - 0.59 10.2 7.0 35 4.5 0.2 5.1 2 2 0 3 3 3 0 Domain of Unknown Function (DUF3856) TOM20_plant PF06552.12 KXL41866.1 - 2 8.1 6.7 6.7 6.4 0.2 3.2 3 1 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_21 PF09976.9 KXL41866.1 - 3.2 7.4 14.9 3.5 7.3 0.2 5.0 3 2 3 6 6 6 0 Tetratricopeptide repeat-like domain MAS20 PF02064.15 KXL41866.1 - 8.2 6.5 11.4 7.8 6.6 0.0 4.7 3 2 2 5 5 5 0 MAS20 protein import receptor AhpC-TSA PF00578.21 KXL41867.1 - 0.016 15.1 0.0 0.02 14.8 0.0 1.1 1 0 0 1 1 1 0 AhpC/TSA family OST3_OST6 PF04756.13 KXL41867.1 - 0.05 12.9 0.1 0.067 12.5 0.1 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family 2OG-FeII_Oxy PF03171.20 KXL41870.1 - 1.8e-05 25.2 0.0 3.4e-05 24.3 0.0 1.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF5060 PF16586.5 KXL41870.1 - 0.01 16.2 0.1 0.013 15.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5060) NADH_4Fe-4S PF10589.9 KXL41870.1 - 0.12 12.5 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region DIOX_N PF14226.6 KXL41871.1 - 6e-16 59.3 0.0 6.3e-16 59.2 0.0 1.0 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Glyco_hydro_3_C PF01915.22 KXL41872.1 - 9.9e-50 169.3 0.0 1.5e-49 168.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXL41872.1 - 9.2e-39 133.7 0.0 1.5e-38 133.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXL41872.1 - 1.7e-14 53.7 0.1 3.3e-14 52.7 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain CTNNB1_binding PF08347.11 KXL41872.1 - 0.028 14.6 0.0 0.073 13.3 0.0 1.7 1 0 0 1 1 1 0 N-terminal CTNNB1 binding zinc_ribbon_16 PF17034.5 KXL41873.1 - 6.8e-25 87.7 12.2 1.8e-24 86.3 12.3 1.7 2 0 0 2 2 2 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 KXL41873.1 - 0.0093 15.6 8.6 0.0093 15.6 8.6 2.2 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type HypA PF01155.19 KXL41873.1 - 0.96 9.5 6.7 1.3 9.1 0.3 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Abhydrolase_6 PF12697.7 KXL41874.1 - 1.6e-06 28.9 3.1 5.2e-06 27.2 0.2 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KXL41874.1 - 1.1e-05 25.3 0.1 0.00018 21.3 0.1 2.1 1 1 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 KXL41874.1 - 0.00089 18.6 0.0 0.0018 17.6 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 KXL41874.1 - 0.0011 18.5 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF900 PF05990.12 KXL41874.1 - 0.022 14.2 2.0 0.053 13.0 0.0 2.3 2 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.25 KXL41874.1 - 0.037 13.9 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) LIDHydrolase PF10230.9 KXL41874.1 - 0.071 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Esterase PF00756.20 KXL41874.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative esterase tRNA_synthFbeta PF17759.1 KXL41875.1 - 5.3e-45 153.5 0.0 7.6e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KXL41875.1 - 2.8e-30 104.3 0.1 7.5e-30 103.0 0.0 1.7 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 KXL41875.1 - 9.2e-24 84.0 0.0 1.6e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KXL41875.1 - 2e-17 63.3 0.0 2.3e-14 53.4 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase B5 domain HEAT_2 PF13646.6 KXL41876.1 - 1.7e-37 127.6 9.4 2.5e-10 40.6 0.0 8.2 3 3 6 9 9 9 9 HEAT repeats HEAT PF02985.22 KXL41876.1 - 4.1e-36 119.9 26.2 0.023 14.9 0.0 13.5 14 0 0 14 14 14 12 HEAT repeat Cnd1 PF12717.7 KXL41876.1 - 3.3e-13 50.0 7.0 0.0017 18.4 0.1 6.5 5 2 2 7 7 7 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KXL41876.1 - 4.3e-11 43.1 10.5 1.2 9.8 0.3 9.9 9 2 2 11 11 11 3 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KXL41876.1 - 9.5e-10 39.0 0.6 0.0028 18.2 0.0 6.4 7 2 2 9 9 9 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KXL41876.1 - 3.1e-06 26.0 6.4 0.18 10.3 0.2 5.2 4 1 1 6 6 6 4 Adaptin N terminal region RTP1_C1 PF10363.9 KXL41876.1 - 4e-05 23.8 3.4 2.3 8.4 0.0 4.7 4 1 1 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 KXL41876.1 - 0.00019 21.4 5.5 6.5 7.0 0.0 6.7 8 0 0 8 8 7 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 KXL41876.1 - 0.00025 20.7 0.6 0.78 9.3 0.0 4.6 3 2 1 4 4 4 1 CLASP N terminal Proteasom_PSMB PF10508.9 KXL41876.1 - 0.053 12.0 0.7 0.83 8.1 0.0 2.3 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit API5 PF05918.11 KXL41876.1 - 0.58 8.9 4.1 7.7 5.2 0.0 3.8 5 1 0 5 5 5 0 Apoptosis inhibitory protein 5 (API5) CAP_N PF01213.19 KXL41876.1 - 8.3 5.8 5.8 15 5.0 4.2 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal RNA_pol_3_Rpc31 PF11705.8 KXL41877.1 - 2.2e-05 24.9 10.7 3.1e-05 24.4 10.7 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Mpp10 PF04006.12 KXL41877.1 - 0.00058 18.5 15.6 0.0007 18.2 15.6 1.0 1 0 0 1 1 1 1 Mpp10 protein SDA1 PF05285.12 KXL41877.1 - 0.00074 19.0 17.0 0.00093 18.7 17.0 1.1 1 0 0 1 1 1 1 SDA1 RNA_polI_A34 PF08208.11 KXL41877.1 - 0.0013 18.9 13.2 0.0018 18.4 13.2 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 SLC12 PF03522.15 KXL41877.1 - 0.0025 16.9 0.5 0.003 16.7 0.5 1.1 1 0 0 1 1 1 1 Solute carrier family 12 Tim54 PF11711.8 KXL41877.1 - 0.0031 16.4 11.3 0.0041 16.0 11.3 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 CPSF100_C PF13299.6 KXL41877.1 - 0.0076 16.4 4.0 0.011 15.9 4.0 1.3 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal SpoIIIAH PF12685.7 KXL41877.1 - 0.0083 16.0 6.3 0.011 15.6 6.3 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein DDHD PF02862.17 KXL41877.1 - 0.012 15.8 0.7 0.015 15.5 0.7 1.2 1 0 0 1 1 1 0 DDHD domain DUF4820 PF16091.5 KXL41877.1 - 0.013 14.9 7.5 0.022 14.1 7.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) BUD22 PF09073.10 KXL41877.1 - 0.018 14.4 14.3 0.023 14.1 14.3 1.1 1 0 0 1 1 1 0 BUD22 SAPS PF04499.15 KXL41877.1 - 0.02 13.7 2.8 0.023 13.5 2.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FYDLN_acid PF09538.10 KXL41877.1 - 0.021 15.5 12.7 0.037 14.7 12.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) SpoIIP PF07454.11 KXL41877.1 - 0.044 13.3 9.6 0.057 12.9 9.6 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Spt20 PF12090.8 KXL41877.1 - 0.049 13.2 7.6 0.065 12.8 7.6 1.1 1 0 0 1 1 1 0 Spt20 family Plasmodium_Vir PF05795.11 KXL41877.1 - 0.049 13.0 4.9 0.063 12.7 4.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4746 PF15928.5 KXL41877.1 - 0.075 12.5 19.6 0.12 11.7 19.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CDC45 PF02724.14 KXL41877.1 - 0.09 11.1 15.2 0.12 10.7 15.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KXL41877.1 - 0.1 10.8 24.7 0.13 10.4 24.7 1.0 1 0 0 1 1 1 0 Nop14-like family DUF913 PF06025.12 KXL41877.1 - 0.11 11.5 5.3 0.14 11.1 5.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PA26 PF04636.13 KXL41877.1 - 0.12 11.3 3.0 0.16 10.9 3.0 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Presenilin PF01080.17 KXL41877.1 - 0.12 11.1 9.2 0.16 10.7 9.2 1.1 1 0 0 1 1 1 0 Presenilin DUF4045 PF13254.6 KXL41877.1 - 0.14 11.8 12.2 0.18 11.4 12.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) FmiP_Thoc5 PF09766.9 KXL41877.1 - 0.16 11.2 12.5 0.22 10.8 12.5 1.1 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 RNA_pol_Rpc4 PF05132.14 KXL41877.1 - 0.18 12.2 7.6 0.29 11.5 7.6 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF868 PF05910.12 KXL41877.1 - 0.19 11.3 0.5 0.28 10.8 0.5 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF868) XAP5 PF04921.14 KXL41877.1 - 0.2 11.5 9.0 0.27 11.0 9.0 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator PI3K_1B_p101 PF10486.9 KXL41877.1 - 0.22 9.2 5.8 0.27 8.9 5.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit MRNIP PF15749.5 KXL41877.1 - 0.28 11.9 11.8 0.46 11.2 11.8 1.2 1 0 0 1 1 1 0 MRN-interacting protein DUF5523 PF17661.1 KXL41877.1 - 0.53 9.9 21.9 0.78 9.4 21.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) SID-1_RNA_chan PF13965.6 KXL41877.1 - 0.58 8.5 1.2 0.67 8.3 1.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Spore_coat_CotO PF14153.6 KXL41877.1 - 0.65 9.9 18.4 0.92 9.4 18.4 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF2151 PF10221.9 KXL41877.1 - 0.68 8.5 8.0 0.86 8.1 8.0 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Prothymosin PF03247.14 KXL41877.1 - 0.98 9.9 40.5 1.7 9.1 40.5 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family MukE PF04288.13 KXL41877.1 - 1 8.2 8.5 1.6 7.6 8.5 1.3 1 0 0 1 1 1 0 MukE-like family Afi1 PF07792.12 KXL41877.1 - 1 9.8 13.3 1.7 9.1 13.3 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF3464 PF11947.8 KXL41877.1 - 1.2 8.9 7.7 1.9 8.2 7.7 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 PIP5K PF01504.18 KXL41877.1 - 1.3 8.2 3.7 1.7 7.8 3.7 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase TRAP_alpha PF03896.16 KXL41877.1 - 1.4 8.1 14.4 2 7.5 14.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Connexin PF00029.19 KXL41877.1 - 1.4 8.6 8.9 2 8.1 8.9 1.2 1 0 0 1 1 1 0 Connexin DUF4471 PF14740.6 KXL41877.1 - 1.5 8.0 6.1 2 7.6 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) Sporozoite_P67 PF05642.11 KXL41877.1 - 1.5 6.8 11.0 1.9 6.4 11.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FancD2 PF14631.6 KXL41877.1 - 1.6 6.0 6.3 2 5.7 6.3 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Eapp_C PF10238.9 KXL41877.1 - 1.8 8.6 9.7 2.8 8.0 9.7 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein NPR3 PF03666.13 KXL41877.1 - 2 7.1 10.6 2.6 6.8 10.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 ALMT PF11744.8 KXL41877.1 - 2 7.2 5.0 2.6 6.8 5.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter RR_TM4-6 PF06459.12 KXL41877.1 - 2.1 8.1 18.0 3 7.6 18.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 BSMAP PF12280.8 KXL41877.1 - 2.6 8.2 4.6 3.8 7.7 4.6 1.2 1 0 0 1 1 1 0 Brain specific membrane anchored protein DUF4637 PF15470.6 KXL41877.1 - 2.9 7.6 20.2 5.8 6.6 20.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) RAB3GAP2_C PF14656.6 KXL41877.1 - 3.4 5.8 11.3 4.7 5.3 11.3 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus RXT2_N PF08595.11 KXL41877.1 - 3.5 7.6 15.7 6 6.9 15.7 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal TFIIF_alpha PF05793.12 KXL41877.1 - 3.5 6.1 27.0 4.9 5.6 27.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FAM60A PF15396.6 KXL41877.1 - 3.6 7.5 5.8 6.2 6.8 5.8 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Smg8_Smg9 PF10220.9 KXL41877.1 - 3.8 5.7 8.3 4.9 5.3 8.3 1.0 1 0 0 1 1 1 0 Smg8_Smg9 V_ATPase_I PF01496.19 KXL41877.1 - 3.8 5.3 13.4 4.8 5.0 13.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_S64 PF08192.11 KXL41877.1 - 4.6 5.6 5.2 5.3 5.4 5.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 PBP1_TM PF14812.6 KXL41877.1 - 5.4 7.5 14.7 14 6.1 14.7 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2828 PF11443.8 KXL41877.1 - 5.6 4.9 9.4 7.6 4.5 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) NOA36 PF06524.12 KXL41877.1 - 5.6 6.2 23.6 9.7 5.4 23.6 1.3 1 0 0 1 1 1 0 NOA36 protein MCM_bind PF09739.9 KXL41877.1 - 6 5.2 10.3 7.8 4.8 10.3 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor CENP-N PF05238.13 KXL41877.1 - 6.2 6.0 9.5 11 5.2 9.5 1.3 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Hid1 PF12722.7 KXL41877.1 - 6.3 4.8 9.8 8.2 4.4 9.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DNA_pol_phi PF04931.13 KXL41877.1 - 6.4 4.7 32.8 8.6 4.3 32.8 1.0 1 0 0 1 1 1 0 DNA polymerase phi MDM10 PF12519.8 KXL41877.1 - 7.6 5.3 6.1 10 4.9 6.1 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Usp PF00582.26 KXL41877.1 - 7.8 7.0 9.0 15 6.1 9.0 1.4 1 0 0 1 1 1 0 Universal stress protein family ESM4 PF15952.5 KXL41877.1 - 7.8 6.9 11.0 12 6.3 11.0 1.2 1 0 0 1 1 1 0 Enhancer of split M4 family ORC_WH_C PF18137.1 KXL41877.1 - 8 6.5 14.6 13 5.8 14.6 1.3 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal DUF3306 PF11748.8 KXL41877.1 - 8.6 7.2 14.6 17 6.3 14.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Mis12 PF05859.12 KXL41878.1 - 3.3e-39 134.0 2.5 3.3e-39 134.0 2.5 2.0 2 0 0 2 2 2 1 Mis12 protein Glyco_H_20C_C PF18088.1 KXL41878.1 - 0.03 14.2 1.9 0.063 13.1 1.9 1.6 1 1 0 1 1 1 0 Glycoside Hydrolase 20C C-terminal domain NPV_P10 PF05531.12 KXL41878.1 - 0.39 11.2 0.1 0.39 11.2 0.1 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Phage_TAC_5 PF08890.11 KXL41878.1 - 1.3 9.1 9.1 0.046 13.7 1.2 2.4 2 2 0 2 2 2 0 Phage XkdN-like tail assembly chaperone protein, TAC PBP-Tp47_a PF14889.6 KXL41879.1 - 0.17 11.5 0.6 8.3 6.0 0.0 2.2 1 1 1 2 2 2 0 Penicillin-binding protein Tp47 domain a RdRP PF05183.12 KXL41880.1 - 1.9e-102 343.8 0.0 2.4e-102 343.5 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase TCTP PF00838.17 KXL41881.1 - 8.8e-72 240.9 4.9 9.8e-72 240.7 4.9 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Chordopox_A33R PF05966.12 KXL41881.1 - 0.0095 15.2 0.1 0.018 14.3 0.0 1.5 1 1 0 1 1 1 1 Chordopoxvirus A33R protein Ribosomal_S20p PF01649.18 KXL41881.1 - 0.048 14.3 1.6 0.071 13.8 1.3 1.4 1 1 0 1 1 1 0 Ribosomal protein S20 Nse4-Nse3_bdg PF15412.6 KXL41881.1 - 0.073 13.2 0.4 0.23 11.6 0.1 2.0 2 0 0 2 2 2 0 Binding domain of Nse4/EID3 to Nse3-MAGE Ribosomal_S8 PF00410.19 KXL41882.1 - 4.9e-22 78.2 0.2 7.2e-22 77.7 0.2 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 His_Phos_1 PF00300.22 KXL41883.1 - 4.2e-20 72.3 0.0 5.8e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ribosomal_L22 PF00237.19 KXL41884.1 - 1.9e-42 143.7 0.1 3.3e-42 142.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Fibrillarin PF01269.17 KXL41885.1 - 9.7e-105 348.7 0.0 1.3e-104 348.3 0.0 1.1 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KXL41885.1 - 4.8e-06 26.4 0.0 7.1e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltr_RsmB-F PF01189.17 KXL41885.1 - 0.0088 15.7 0.0 0.019 14.6 0.0 1.5 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 KXL41885.1 - 0.013 15.3 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) HMG_box PF00505.19 KXL41886.1 - 9.1e-14 51.6 8.8 3.7e-12 46.5 8.8 2.0 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXL41886.1 - 1e-05 26.0 5.6 2.2e-05 24.9 5.6 1.5 1 1 0 1 1 1 1 HMG-box domain Ofd1_CTDD PF10637.9 KXL41886.1 - 0.037 13.4 0.3 0.041 13.2 0.3 1.0 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term DUF4192 PF13830.6 KXL41886.1 - 0.15 12.1 1.8 0.17 11.9 1.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) APP_amyloid PF10515.9 KXL41886.1 - 3 8.4 6.2 37 4.9 6.2 2.3 1 1 0 1 1 1 0 Beta-amyloid precursor protein C-terminus PRKCSH-like PF12999.7 KXL41887.1 - 1.4e-44 152.0 1.6 8.1e-43 146.2 1.6 2.4 1 1 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 KXL41887.1 - 3.2e-31 108.1 0.1 9.3e-31 106.6 0.0 1.7 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 KXL41887.1 - 3.4e-11 44.0 0.0 7e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein ATG27 PF09451.10 KXL41887.1 - 0.024 14.5 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Autophagy-related protein 27 Prefoldin_2 PF01920.20 KXL41887.1 - 0.13 12.2 3.0 4.4 7.3 0.4 3.0 3 0 0 3 3 3 0 Prefoldin subunit CENP-F_leu_zip PF10473.9 KXL41887.1 - 0.14 12.2 4.6 12 5.9 0.2 3.0 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ribosomal_L9_N PF01281.19 KXL41888.1 - 1.8e-10 40.2 0.0 4.2e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Cyclin_N PF00134.23 KXL41889.1 - 2.1e-13 50.1 0.2 5.7e-13 48.7 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 KXL41889.1 - 0.013 15.5 2.3 0.31 11.1 0.2 2.4 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Peptidase_M29 PF02073.15 KXL41889.1 - 0.079 11.7 0.1 0.1 11.4 0.1 1.1 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) Pkinase PF00069.25 KXL41890.1 - 1.1e-50 172.4 0.0 1.8e-50 171.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL41890.1 - 2.1e-24 86.2 0.0 5.8e-24 84.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KXL41890.1 - 0.00089 19.2 2.9 0.043 13.7 0.1 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KXL41890.1 - 0.027 13.8 0.3 2.7 7.2 0.1 2.5 2 1 0 2 2 2 0 Kinase-like Pox_ser-thr_kin PF05445.11 KXL41890.1 - 0.047 12.7 0.1 0.067 12.2 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pribosyltran PF00156.27 KXL41891.1 - 6.1e-07 29.1 0.0 9.3e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain VHS PF00790.19 KXL41892.1 - 8.1e-35 119.7 0.1 1.3e-34 119.0 0.1 1.3 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 KXL41892.1 - 3.7e-16 58.4 0.0 1e-15 57.1 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KXL41892.1 - 5.9e-14 51.7 0.1 1.4e-13 50.5 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXL41892.1 - 2.9e-12 46.1 0.0 8.8e-12 44.5 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 KXL41892.1 - 5.1e-08 33.1 0.0 1.5e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 GAT domain UIM PF02809.20 KXL41892.1 - 0.015 15.2 3.2 0.046 13.6 3.2 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif Cyt-b5 PF00173.28 KXL41893.1 - 6.7e-22 77.4 0.1 8.7e-22 77.1 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF347 PF03988.12 KXL41893.1 - 0.023 14.9 1.0 0.035 14.3 1.0 1.3 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) MGC-24 PF05283.11 KXL41893.1 - 0.18 12.2 0.1 0.41 11.1 0.0 1.5 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin ArfGap PF01412.18 KXL41894.1 - 6.9e-41 139.0 1.3 1.1e-40 138.4 1.3 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Pkinase PF00069.25 KXL41895.1 - 1.1e-14 54.4 0.0 3.4e-14 52.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL41895.1 - 0.00047 19.5 0.0 0.0023 17.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase HET PF06985.11 KXL41896.1 - 4.5e-35 121.1 0.2 6.8e-35 120.6 0.2 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Oxidored_FMN PF00724.20 KXL41897.1 - 3.7e-64 217.1 0.0 4.6e-64 216.9 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 KXL41897.1 - 0.005 16.0 0.0 0.017 14.2 0.0 1.9 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) Glyco_hydro_114 PF03537.13 KXL41897.1 - 0.079 12.3 0.3 0.44 9.8 0.2 2.0 1 1 0 1 1 1 0 Glycoside-hydrolase family GH114 ATP12 PF07542.11 KXL41898.1 - 2.5e-43 147.2 0.2 2.5e-43 147.2 0.2 1.9 3 0 0 3 3 3 1 ATP12 chaperone protein MFS_MOT1 PF16983.5 KXL41900.1 - 3.6e-64 214.1 30.8 7.2e-34 116.5 9.3 2.8 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily PAP2_3 PF14378.6 KXL41901.1 - 1.3e-23 83.7 24.4 3.7e-20 72.4 4.7 2.9 4 0 0 4 4 4 2 PAP2 superfamily Aldedh PF00171.22 KXL41902.1 - 3.4e-77 259.9 0.0 4.1e-77 259.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pkinase PF00069.25 KXL41903.1 - 2e-67 227.4 0.0 2.4e-67 227.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL41903.1 - 3.6e-32 111.7 0.0 5.1e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXL41903.1 - 0.014 14.4 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KXL41903.1 - 0.037 13.4 0.0 0.073 12.4 0.1 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXL41903.1 - 0.042 13.8 0.1 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Zn_clus PF00172.18 KXL41907.1 - 1.4e-09 37.9 9.6 2e-09 37.4 9.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clusterin PF01093.17 KXL41907.1 - 0.23 10.5 1.5 0.29 10.1 1.5 1.1 1 0 0 1 1 1 0 Clusterin NUDIX PF00293.28 KXL41909.1 - 5.3e-07 29.7 0.0 2.8e-06 27.4 0.0 2.3 2 1 0 2 2 2 1 NUDIX domain Tim54 PF11711.8 KXL41911.1 - 0.001 17.9 0.0 0.0015 17.4 0.0 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Radial_spoke PF04712.12 KXL41911.1 - 0.0032 16.5 0.7 0.004 16.2 0.7 1.2 1 0 0 1 1 1 1 Radial spokehead-like protein FAM176 PF14851.6 KXL41911.1 - 0.23 11.1 2.7 0.37 10.4 2.7 1.3 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.10 KXL41911.1 - 0.28 11.6 11.0 0.53 10.7 11.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PPTA PF01239.22 KXL41912.1 - 1.8 8.4 6.0 1.1 9.1 1.6 2.3 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat TRP PF06011.12 KXL41913.1 - 1.8e-39 135.7 23.2 8.7e-38 130.1 23.2 2.1 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KXL41913.1 - 1.7e-21 77.1 0.1 2.9e-21 76.3 0.1 1.4 1 0 0 1 1 1 1 ML-like domain FeoB_C PF07664.12 KXL41913.1 - 0.95 9.2 3.0 0.67 9.7 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus OppC_N PF12911.7 KXL41913.1 - 1.3 9.0 6.7 6 6.9 0.3 3.2 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C DUF2231 PF09990.9 KXL41915.1 - 0.0001 22.7 1.0 0.00074 19.9 1.0 2.1 1 1 0 1 1 1 1 Predicted membrane protein (DUF2231) B1 PF02246.15 KXL41915.1 - 0.078 13.0 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein L b1 domain SR-25 PF10500.9 KXL41916.1 - 0.00099 18.8 6.6 0.0012 18.5 6.6 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein MLANA PF14991.6 KXL41916.1 - 0.037 14.3 3.8 0.041 14.2 0.4 2.1 2 0 0 2 2 2 0 Protein melan-A Presenilin PF01080.17 KXL41916.1 - 3.3 6.4 4.5 4.1 6.1 4.5 1.1 1 0 0 1 1 1 0 Presenilin Tim17 PF02466.19 KXL41917.1 - 0.012 15.9 7.2 0.026 14.9 7.1 1.6 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family RNB PF00773.19 KXL41918.1 - 2.2e-57 194.9 0.0 5.5e-57 193.5 0.0 1.7 1 0 0 1 1 1 1 RNB domain DUF305 PF03713.13 KXL41918.1 - 0.25 11.4 2.5 14 5.8 0.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF305) Thiolase_N PF00108.23 KXL41919.1 - 6e-13 48.7 0.0 4.1e-12 46.0 0.0 2.2 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXL41919.1 - 4.7e-10 39.2 0.3 4e-09 36.2 0.1 2.5 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KXL41919.1 - 2.1e-07 30.7 0.0 1.8e-05 24.5 0.1 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 KXL41919.1 - 0.00017 21.2 0.3 0.00058 19.5 0.3 1.8 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 KXL41919.1 - 0.014 14.2 0.0 0.03 13.1 0.0 1.5 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) Ketoacyl-synt_C PF02801.22 KXL41919.1 - 0.023 14.7 0.0 0.42 10.6 0.0 2.5 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain Myb_DNA-bind_3 PF12776.7 KXL41920.1 - 0.0017 19.3 1.4 0.0051 17.8 1.4 1.7 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXL41920.1 - 0.093 13.0 2.1 0.099 12.9 0.2 2.0 1 1 1 2 2 2 0 Myb-like DNA-binding domain Keratin PF02422.16 KXL41920.1 - 0.12 12.1 2.5 0.24 11.1 2.5 1.5 1 0 0 1 1 1 0 Keratin eRF1_1 PF03463.15 KXL41921.1 - 3.3e-51 172.7 0.1 6e-51 171.8 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 1 Ribonuc_L-PSP PF01042.21 KXL41921.1 - 9.4e-37 125.7 0.0 5.6e-36 123.2 0.0 2.2 2 1 1 3 3 3 1 Endoribonuclease L-PSP eRF1_3 PF03465.15 KXL41921.1 - 5.9e-19 68.6 0.0 1.2e-18 67.7 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 KXL41921.1 - 6.1e-17 62.2 0.0 1e-16 61.5 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 Peptidase_M99_m PF17130.4 KXL41921.1 - 0.032 14.2 0.0 0.066 13.2 0.0 1.5 1 0 0 1 1 1 0 beta-barrel domain of carboxypeptidase M99 Aldo_ket_red PF00248.21 KXL41922.1 - 2.8e-38 131.8 0.0 3.9e-36 124.7 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family PilM PF07419.12 KXL41922.1 - 0.074 13.2 0.0 0.4 10.8 0.0 2.0 2 0 0 2 2 2 0 PilM Cellulase PF00150.18 KXL41923.1 - 2.1e-12 47.1 0.8 1.2e-11 44.6 0.0 2.1 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) GPI-anchored PF10342.9 KXL41924.1 - 1.2e-23 83.7 0.3 1.2e-23 83.7 0.3 2.7 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ER_lumen_recept PF00810.18 KXL41925.1 - 5.7e-41 140.8 8.2 8.8e-41 140.2 8.2 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KXL41925.1 - 0.052 13.3 0.1 0.052 13.3 0.1 3.3 4 0 0 4 4 4 0 PQ loop repeat HisKA_4TM PF16926.5 KXL41925.1 - 0.1 12.2 0.4 0.17 11.4 0.4 1.3 1 0 0 1 1 1 0 Archaeal 4TM region of histidine kinase DMT_YdcZ PF04657.13 KXL41925.1 - 4.1 7.7 6.3 6 7.1 2.3 2.3 2 1 0 2 2 2 0 Putative inner membrane exporter, YdcZ GidB PF02527.15 KXL41926.1 - 0.011 15.0 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Mito_fiss_reg PF05308.11 KXL41928.1 - 0.17 11.9 0.7 0.22 11.6 0.7 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 KXL41928.1 - 0.51 9.8 2.6 0.67 9.4 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal IMS PF00817.20 KXL41930.1 - 1.2e-36 126.0 0.0 2.7e-36 124.8 0.0 1.6 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 KXL41930.1 - 8.1e-15 55.6 0.4 3.2e-14 53.6 0.2 2.1 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain APG6_N PF17675.1 KXL41931.1 - 0.00011 22.8 6.0 0.0003 21.3 6.0 1.6 1 1 0 1 1 1 1 Apg6 coiled-coil region PspA_IM30 PF04012.12 KXL41931.1 - 0.00075 19.1 0.4 0.0013 18.3 0.4 1.4 1 1 0 1 1 1 1 PspA/IM30 family Cep57_CLD_2 PF14197.6 KXL41931.1 - 0.00089 19.3 14.8 0.039 14.0 0.3 3.1 2 1 1 3 3 3 2 Centrosome localisation domain of PPC89 DUF4201 PF13870.6 KXL41931.1 - 0.0031 17.3 5.3 0.0031 17.3 5.3 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) DUF4140 PF13600.6 KXL41931.1 - 0.0065 16.9 0.1 0.02 15.3 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) CENP-F_leu_zip PF10473.9 KXL41931.1 - 0.011 15.7 6.9 0.037 14.1 4.4 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KXL41931.1 - 0.013 14.4 3.7 0.013 14.4 3.7 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein GAS PF13851.6 KXL41931.1 - 0.017 14.4 3.3 0.017 14.4 3.3 1.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Lipoprotein_20 PF13942.6 KXL41931.1 - 0.04 13.8 1.1 0.07 13.0 0.4 1.7 2 0 0 2 2 2 0 YfhG lipoprotein Prominin PF05478.11 KXL41931.1 - 0.044 11.8 0.1 0.042 11.8 0.1 1.1 1 0 0 1 1 1 0 Prominin TPR_MLP1_2 PF07926.12 KXL41931.1 - 0.05 13.7 7.2 0.17 11.9 3.6 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 KXL41931.1 - 0.062 12.6 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Laminin_II PF06009.12 KXL41931.1 - 0.062 13.3 1.3 0.12 12.4 1.3 1.4 1 0 0 1 1 1 0 Laminin Domain II HAP1_N PF04849.13 KXL41931.1 - 0.11 11.7 6.5 0.035 13.3 3.6 1.5 2 0 0 2 2 2 0 HAP1 N-terminal conserved region FliJ PF02050.16 KXL41931.1 - 0.12 12.7 6.1 0.063 13.5 2.2 1.9 2 0 0 2 2 2 0 Flagellar FliJ protein YabA PF06156.13 KXL41931.1 - 0.12 13.0 4.1 0.094 13.4 1.7 1.8 2 0 0 2 2 2 0 Initiation control protein YabA DHR10 PF18595.1 KXL41931.1 - 0.13 12.3 10.0 1.1 9.4 5.5 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Bcr-Abl_Oligo PF09036.10 KXL41931.1 - 0.17 11.9 1.6 0.63 10.1 1.0 2.1 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DivIVA PF05103.13 KXL41931.1 - 0.3 11.2 5.4 0.56 10.3 2.7 2.1 2 0 0 2 2 2 0 DivIVA protein UPF0242 PF06785.11 KXL41931.1 - 0.4 10.8 6.6 0.13 12.3 3.5 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus PI3K_P85_iSH2 PF16454.5 KXL41931.1 - 0.88 9.2 8.0 2 8.0 8.0 1.6 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Spc24 PF08286.11 KXL41931.1 - 1.1 9.5 5.2 0.49 10.7 3.0 1.6 2 0 0 2 2 1 0 Spc24 subunit of Ndc80 DivIC PF04977.15 KXL41931.1 - 3.7 7.4 6.3 3.8 7.3 5.1 1.7 2 1 0 2 2 2 0 Septum formation initiator RFC1 PF08519.12 KXL41932.1 - 6.2e-50 169.4 0.0 1.4e-49 168.3 0.0 1.6 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 KXL41932.1 - 1.1e-14 54.6 0.0 2.7e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 KXL41932.1 - 1.4e-09 38.5 0.0 3.2e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KXL41932.1 - 9.2e-07 29.0 0.0 2.3e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KXL41932.1 - 0.00015 22.1 0.0 0.00035 20.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXL41932.1 - 0.0028 17.8 0.1 0.0093 16.1 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXL41932.1 - 0.0041 17.5 1.6 0.0072 16.7 0.1 2.2 2 1 0 2 2 1 1 AAA ATPase domain AAA_30 PF13604.6 KXL41932.1 - 0.022 14.5 0.0 0.063 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain PTCB-BRCT PF12738.7 KXL41932.1 - 0.024 14.6 0.0 0.055 13.4 0.0 1.7 1 0 0 1 1 1 0 twin BRCT domain AAA_18 PF13238.6 KXL41932.1 - 0.03 14.9 0.0 0.094 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KXL41932.1 - 0.032 14.0 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KXL41932.1 - 0.035 14.4 0.1 0.035 14.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KXL41932.1 - 0.05 13.6 0.0 0.16 12.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_5 PF07728.14 KXL41932.1 - 0.056 13.5 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 KXL41932.1 - 0.073 13.0 0.0 0.4 10.6 0.0 2.1 2 0 0 2 2 2 0 NACHT domain DNA_pol3_delta PF06144.13 KXL41932.1 - 0.19 11.5 0.0 0.41 10.4 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_11 PF13086.6 KXL41932.1 - 6.9 6.4 9.7 1.1 9.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain Ribosomal_L16 PF00252.18 KXL41933.1 - 7.8e-31 106.8 0.0 1.3e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_L32p PF01783.23 KXL41933.1 - 0.2 12.0 0.1 0.2 12.0 0.1 2.0 3 0 0 3 3 3 0 Ribosomal L32p protein family Methyltransf_2 PF00891.18 KXL41935.1 - 1e-18 67.4 0.0 1.4e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain NinB PF05772.12 KXL41935.1 - 0.011 15.6 0.0 0.035 13.9 0.0 1.8 2 0 0 2 2 2 0 NinB protein Methyltransf_23 PF13489.6 KXL41935.1 - 0.014 15.2 0.0 0.05 13.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Choline_sulf_C PF12411.8 KXL41935.1 - 0.1 12.4 0.6 0.23 11.3 0.6 1.5 1 0 0 1 1 1 0 Choline sulfatase enzyme C terminal MFS_1 PF07690.16 KXL41936.1 - 2.1e-32 112.5 22.5 2.1e-32 112.5 22.5 1.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL41936.1 - 1.8e-13 50.2 22.5 5e-13 48.7 22.5 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter DUF21 PF01595.20 KXL41936.1 - 6 6.5 10.2 60 3.3 10.2 2.5 1 1 0 1 1 1 0 Cyclin M transmembrane N-terminal domain DUF2236 PF09995.9 KXL41937.1 - 3e-33 115.9 0.1 4.4e-33 115.4 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF5440 PF17509.2 KXL41937.1 - 0.078 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5440) RasGEF PF00617.19 KXL41938.1 - 5.7e-46 156.9 0.0 1e-45 156.1 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KXL41938.1 - 2.9e-12 46.7 0.0 1.1e-11 44.9 0.0 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif Ras PF00071.22 KXL41938.1 - 1.1e-06 28.3 0.0 3.2e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 Ras family AAA_16 PF13191.6 KXL41938.1 - 0.0036 17.7 0.1 0.034 14.5 0.0 2.6 2 2 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KXL41938.1 - 0.0061 17.1 0.0 0.75 10.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain Spore_IV_A PF09547.10 KXL41938.1 - 0.022 13.7 0.0 0.07 12.1 0.0 1.7 2 0 0 2 2 2 0 Stage IV sporulation protein A (spore_IV_A) MMR_HSR1 PF01926.23 KXL41938.1 - 0.049 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 KXL41938.1 - 0.072 12.4 0.0 0.17 11.2 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family NTPase_1 PF03266.15 KXL41938.1 - 0.092 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.6 KXL41938.1 - 0.15 11.8 0.0 0.4 10.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KXL41938.1 - 0.2 11.4 0.2 0.99 9.1 0.0 2.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein OSCP PF00213.18 KXL41940.1 - 9.1e-48 162.6 1.0 1.1e-47 162.4 1.0 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Amino_oxidase PF01593.24 KXL41941.1 - 2.9e-13 49.9 0.0 1.7e-10 40.8 0.0 2.5 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXL41941.1 - 7.4e-12 45.3 0.0 2e-11 44.0 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXL41941.1 - 0.00026 20.7 0.0 0.0073 15.9 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXL41941.1 - 0.0024 17.2 0.0 0.0038 16.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXL41941.1 - 0.011 14.9 0.1 0.022 13.9 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 KXL41941.1 - 0.022 14.8 0.1 0.19 11.7 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding FMO-like PF00743.19 KXL41941.1 - 0.035 12.5 0.0 0.095 11.1 0.0 1.6 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like HI0933_like PF03486.14 KXL41941.1 - 0.048 12.4 0.0 0.09 11.5 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 KXL41941.1 - 0.06 13.9 0.0 0.23 12.1 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UL20 PF17582.2 KXL41941.1 - 0.095 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL20 Thi4 PF01946.17 KXL41941.1 - 0.12 11.6 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 KXL41941.1 - 0.2 10.7 0.1 0.28 10.2 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KXL41941.1 - 0.22 10.8 0.0 0.36 10.1 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain V-SNARE PF05008.15 KXL41942.1 - 2.1e-18 66.5 3.7 2.1e-18 66.5 3.7 1.9 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 KXL41942.1 - 1.9e-17 63.3 4.9 1.9e-17 63.3 4.9 2.9 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Fusion_gly PF00523.18 KXL41942.1 - 0.0015 16.8 0.8 0.0054 15.0 0.1 1.9 2 0 0 2 2 2 1 Fusion glycoprotein F0 Sec20 PF03908.13 KXL41942.1 - 0.021 14.7 1.6 0.039 13.9 0.2 2.2 2 2 0 2 2 2 0 Sec20 Synaptobrevin PF00957.21 KXL41942.1 - 0.039 13.7 3.2 0.08 12.7 1.5 2.3 1 1 1 2 2 2 0 Synaptobrevin Spectrin PF00435.21 KXL41942.1 - 0.048 14.1 3.3 0.15 12.6 0.4 2.6 1 1 2 3 3 3 0 Spectrin repeat RIFIN PF02009.16 KXL41942.1 - 0.081 12.8 0.9 3.1 7.6 0.1 2.2 2 0 0 2 2 2 0 Rifin Prominin PF05478.11 KXL41942.1 - 0.094 10.7 1.8 1.1 7.1 0.2 2.0 2 0 0 2 2 2 0 Prominin SKA2 PF16740.5 KXL41942.1 - 0.36 10.6 5.5 1.8 8.4 0.9 3.0 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 OppC_N PF12911.7 KXL41942.1 - 1.5 8.9 3.0 2.6 8.1 3.0 1.3 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C RCC1_2 PF13540.6 KXL41943.1 - 2.8e-11 42.9 2.7 3.8e-05 23.4 0.3 4.3 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 KXL41943.1 - 3.7e-11 43.5 4.1 0.0011 19.5 0.1 4.6 4 1 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat Dabb PF07876.12 KXL41944.1 - 1.8e-23 83.0 0.0 2e-23 82.8 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF2407_C PF13373.6 KXL41945.1 - 1.7e-39 135.2 0.0 2.4e-39 134.7 0.0 1.2 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 KXL41945.1 - 2.5e-26 92.2 0.0 3.8e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 KXL41945.1 - 0.0011 18.6 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 KXL41945.1 - 0.0031 17.6 0.0 0.0052 16.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TIP49 PF06068.13 KXL41946.1 - 3.2e-149 496.9 0.0 1.7e-148 494.5 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain TIP49_C PF17856.1 KXL41946.1 - 5.3e-12 45.7 0.0 1.2e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KXL41946.1 - 1.3e-11 45.1 0.0 1.1e-06 29.1 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXL41946.1 - 1.3e-09 38.0 0.0 5.2e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXL41946.1 - 3.3e-06 27.6 0.9 5.1e-05 23.7 0.9 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXL41946.1 - 2.7e-05 24.5 0.1 0.32 11.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KXL41946.1 - 0.0015 17.8 0.5 0.0049 16.2 0.2 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.6 KXL41946.1 - 0.0025 17.4 0.1 0.0047 16.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KXL41946.1 - 0.0026 18.0 0.1 0.0047 17.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXL41946.1 - 0.0069 16.4 0.1 0.092 12.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KXL41946.1 - 0.0073 16.0 1.7 1.7 8.3 0.1 2.9 3 0 0 3 3 3 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 KXL41946.1 - 0.04 13.7 0.1 0.081 12.7 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.9 KXL41946.1 - 0.041 13.1 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KXL41946.1 - 0.05 13.9 1.8 0.49 10.7 1.8 2.1 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXL41946.1 - 0.069 13.7 0.0 0.16 12.5 0.0 1.6 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 KXL41946.1 - 0.071 12.5 0.1 0.92 8.8 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KXL41946.1 - 0.074 13.2 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 KXL41946.1 - 0.077 12.3 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain ATPase PF06745.13 KXL41946.1 - 0.097 12.0 0.1 0.36 10.1 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_17 PF13207.6 KXL41946.1 - 0.11 12.9 0.2 0.29 11.5 0.1 1.8 2 0 0 2 2 1 0 AAA domain DUF815 PF05673.13 KXL41946.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 KXL41946.1 - 0.17 11.4 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Fe-S_biosyn PF01521.20 KXL41947.1 - 3.8e-18 65.7 0.0 4.3e-18 65.5 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Cu-oxidase_3 PF07732.15 KXL41948.1 - 1.6e-37 128.1 0.6 1.6e-37 128.1 0.6 3.4 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 KXL41948.1 - 4.3e-33 114.7 0.8 3.6e-31 108.4 0.0 3.1 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXL41948.1 - 2.6e-28 98.4 0.9 2.6e-28 98.4 0.9 3.6 3 1 0 3 3 3 2 Multicopper oxidase Erg28 PF03694.13 KXL41949.1 - 1.4 9.3 6.8 0.42 11.0 0.7 2.4 2 0 0 2 2 2 0 Erg28 like protein Metallophos PF00149.28 KXL41950.1 - 6.8e-14 52.9 0.0 1.1e-13 52.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXL41950.1 - 1.3e-10 41.7 0.1 7.1e-07 29.6 0.1 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Oxidored_FMN PF00724.20 KXL41951.1 - 2.1e-94 316.6 0.0 2.4e-94 316.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Sporozoite_P67 PF05642.11 KXL41952.1 - 0.015 13.4 4.6 0.017 13.3 4.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TraT PF05818.12 KXL41952.1 - 0.03 14.0 1.8 0.045 13.4 1.8 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF1269 PF06897.12 KXL41952.1 - 0.051 13.9 0.3 0.051 13.9 0.3 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1269) Gly-zipper_Omp PF13488.6 KXL41952.1 - 4.2 7.4 28.7 2.5 8.2 0.4 2.3 2 0 0 2 2 2 0 Glycine zipper DUF1145 PF06611.12 KXL41953.1 - 0.16 12.0 4.6 0.29 11.1 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1145) dCMP_cyt_deam_1 PF00383.23 KXL41954.1 - 6.4e-12 45.2 0.2 9.7e-12 44.7 0.2 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXL41954.1 - 2.5e-08 33.7 0.0 3.1e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC3 PF18771.1 KXL41954.1 - 0.0091 16.1 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 1 APOBEC3 SNAD4 PF18750.1 KXL41954.1 - 0.015 15.4 0.0 0.023 14.8 0.0 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 Bd3614-deam PF14439.6 KXL41954.1 - 0.018 15.1 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase FAM220 PF15487.6 KXL41956.1 - 0.58 9.7 4.1 0.81 9.3 4.1 1.2 1 0 0 1 1 1 0 FAM220 family Dicty_REP PF05086.12 KXL41956.1 - 7 4.5 7.7 8.8 4.2 7.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SAGA-Tad1 PF12767.7 KXL41957.1 - 0.00049 19.9 0.0 0.00095 19.0 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit DUF2477 PF10631.9 KXL41957.1 - 0.38 11.4 4.3 1.2 9.8 4.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) DUF5384 PF17358.2 KXL41957.1 - 0.66 10.0 9.5 1.3 9.1 9.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5384) HRDC PF00570.23 KXL41959.1 - 0.018 15.0 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 HRDC domain DEAD PF00270.29 KXL41960.1 - 2.8e-23 82.6 0.0 5.9e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXL41960.1 - 1.2e-22 80.3 0.0 2.8e-18 66.3 0.0 2.8 3 0 0 3 3 3 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KXL41960.1 - 3.4e-18 66.1 13.1 4.9e-18 65.6 9.7 2.9 3 0 0 3 3 3 1 RecQ zinc-binding RQC PF09382.10 KXL41960.1 - 1.2e-16 60.5 0.0 3e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 RQC domain ResIII PF04851.15 KXL41960.1 - 5e-06 26.6 0.0 9.7e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KXL41960.1 - 0.00087 18.1 0.0 0.0016 17.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain CC2-LZ PF16516.5 KXL41960.1 - 0.067 13.6 0.3 0.067 13.6 0.3 2.3 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator AAA_22 PF13401.6 KXL41960.1 - 1 9.6 4.5 21 5.4 0.5 3.9 4 1 1 5 5 5 0 AAA domain Pyridoxal_deC PF00282.19 KXL41961.1 - 9.1e-23 80.6 0.0 3e-21 75.6 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KXL41961.1 - 0.00026 20.4 0.0 0.00032 20.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KXL41961.1 - 0.0043 16.3 0.0 0.0083 15.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KXL41961.1 - 0.12 11.3 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Glyco_hydro_18 PF00704.28 KXL41963.1 - 3.1e-88 296.5 0.5 3.6e-88 296.3 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Phage_r1t_holin PF16945.5 KXL41963.1 - 0.022 14.9 0.0 0.041 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative lactococcus lactis phage r1t holin Zn_clus PF00172.18 KXL41965.1 - 4.6e-09 36.3 13.5 8.8e-09 35.4 13.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldose_epim PF01263.20 KXL41966.1 - 4e-55 187.2 0.0 5.7e-55 186.7 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase NmrA PF05368.13 KXL41968.1 - 6.2e-55 186.3 0.0 6.9e-55 186.1 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXL41968.1 - 4.8e-10 39.6 0.0 6.1e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NAP PF00956.18 KXL41971.1 - 5e-16 58.7 0.0 1.4e-15 57.2 0.0 1.5 1 1 1 2 2 2 1 Nucleosome assembly protein (NAP) tRNA_anti-codon PF01336.25 KXL41972.1 - 0.026 14.5 0.1 0.61 10.1 0.0 2.5 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain AMP-binding PF00501.28 KXL41973.1 - 1.5e-71 241.2 0.0 2e-71 240.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXL41973.1 - 8.4e-14 52.3 0.2 2e-13 51.1 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Minor_tail_Z PF06763.11 KXL41974.1 - 0.089 12.6 0.2 0.14 11.9 0.2 1.3 1 0 0 1 1 1 0 Prophage minor tail protein Z (GPZ) Cation_efflux PF01545.21 KXL41975.1 - 1.3e-55 188.2 2.0 6.2e-55 186.0 2.0 1.8 1 1 0 1 1 1 1 Cation efflux family Thioredoxin PF00085.20 KXL41976.1 - 5.4e-30 103.4 0.0 5.8e-24 84.1 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 KXL41976.1 - 1.7e-06 28.5 0.0 0.011 16.2 0.0 2.6 1 1 1 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KXL41976.1 - 2.9e-05 23.6 0.0 0.00021 20.8 0.0 2.0 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family TraF PF13728.6 KXL41976.1 - 0.00023 21.0 2.0 0.03 14.1 0.0 3.1 3 0 0 3 3 3 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 KXL41976.1 - 0.012 15.9 0.0 16 5.9 0.0 3.5 2 1 1 3 3 3 0 Thioredoxin-like AhpC-TSA PF00578.21 KXL41976.1 - 0.022 14.7 0.0 0.063 13.2 0.0 1.7 1 0 0 1 1 1 0 AhpC/TSA family ERp29_N PF07912.13 KXL41976.1 - 0.045 13.9 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 ERp29, N-terminal domain Thioredoxin_7 PF13899.6 KXL41976.1 - 0.059 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Vta1 PF04652.16 KXL41977.1 - 1.3e-46 158.1 5.3 2.4e-46 157.3 4.0 1.9 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 KXL41977.1 - 2.9e-16 58.9 0.4 7e-16 57.7 0.1 1.9 2 0 0 2 2 2 1 Vta1 C-terminal domain Sugar_tr PF00083.24 KXL41978.1 - 1e-114 383.9 25.1 1.3e-114 383.6 25.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL41978.1 - 7e-23 81.1 34.0 1.3e-22 80.2 24.4 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3671 PF12420.8 KXL41978.1 - 1.2 9.3 4.1 3 7.9 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function TssO PF17561.2 KXL41978.1 - 1.5 8.9 4.0 2.5 8.2 0.4 2.3 2 0 0 2 2 2 0 Type VI secretion system, TssO Pkinase PF00069.25 KXL41979.1 - 1.1e-49 169.2 0.0 1.6e-49 168.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL41979.1 - 3.3e-31 108.5 0.0 5e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXL41979.1 - 1.3e-06 28.0 0.0 1.6e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like RRN3 PF05327.11 KXL41981.1 - 3.5e-161 537.5 0.0 3.5e-161 537.5 0.0 2.0 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 DUF262 PF03235.14 KXL41981.1 - 0.029 14.5 0.3 0.029 14.5 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF262 IBN_N PF03810.19 KXL41981.1 - 0.058 13.3 0.1 0.15 12.0 0.1 1.7 1 0 0 1 1 1 0 Importin-beta N-terminal domain Sigma70_ner PF04546.13 KXL41981.1 - 0.25 11.2 15.6 2 8.3 3.0 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region Vps53_N PF04100.12 KXL41982.1 - 7.5e-107 357.6 5.6 7.5e-107 357.6 5.6 1.7 2 0 0 2 2 2 1 Vps53-like, N-terminal DUF2451 PF10474.9 KXL41982.1 - 1.3e-08 34.9 0.1 4.1e-08 33.3 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 KXL41982.1 - 4.8e-08 32.6 9.1 8.6e-08 31.8 9.1 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Gp58 PF07902.11 KXL41982.1 - 0.069 11.4 4.8 0.11 10.7 4.8 1.2 1 0 0 1 1 1 0 gp58-like protein RecG_N PF17190.4 KXL41982.1 - 0.14 12.9 3.9 0.11 13.3 1.2 2.3 2 0 0 2 2 2 0 RecG N-terminal helical domain Spc7 PF08317.11 KXL41982.1 - 0.31 9.9 9.9 0.34 9.8 8.5 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein COG2 PF06148.11 KXL41982.1 - 8.7 6.4 13.3 0.97 9.5 6.1 2.9 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 PHD PF00628.29 KXL41983.1 - 5.1e-05 23.1 19.7 0.00027 20.8 5.7 2.5 2 0 0 2 2 2 2 PHD-finger FYVE_2 PF02318.16 KXL41983.1 - 0.012 15.9 1.9 0.012 15.9 1.9 2.5 2 1 0 2 2 2 0 FYVE-type zinc finger Spc7_N PF15402.6 KXL41983.1 - 0.047 11.9 5.2 0.063 11.5 5.2 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Amino_oxidase PF01593.24 KXL41984.1 - 1.6e-79 268.4 0.0 1.7e-77 261.6 0.0 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.17 KXL41984.1 - 6.8e-16 58.4 0.0 1.4e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain HMG_box PF00505.19 KXL41984.1 - 2.8e-07 30.9 6.3 6.9e-06 26.4 0.2 2.7 1 1 1 2 2 2 2 HMG (high mobility group) box NAD_binding_8 PF13450.6 KXL41984.1 - 6.7e-07 29.5 0.0 1.4e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXL41984.1 - 0.00043 20.0 0.0 0.0012 18.5 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXL41984.1 - 0.0026 17.0 0.1 0.02 14.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HMG_box_2 PF09011.10 KXL41984.1 - 0.042 14.5 0.8 0.042 14.5 0.8 3.0 2 1 1 3 3 3 0 HMG-box domain AlaDh_PNT_C PF01262.21 KXL41984.1 - 0.081 12.2 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 KXL41984.1 - 0.097 12.7 0.0 0.97 9.4 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding bacHORMA_1 PF18138.1 KXL41985.1 - 0.0075 16.2 0.4 0.013 15.4 0.4 1.3 1 0 0 1 1 1 1 Bacterial HORMA domain family 1 UCH PF00443.29 KXL41986.1 - 3.3e-55 187.4 0.3 5.8e-55 186.6 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXL41986.1 - 2.3e-26 93.2 0.6 1.9e-19 70.4 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KXL41986.1 - 0.0029 17.1 2.1 0.051 13.0 1.2 2.6 2 0 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF3731 PF12531.8 KXL41986.1 - 0.073 12.9 3.1 0.14 12.0 3.1 1.4 1 0 0 1 1 1 0 DNA-K related protein EMC3_TMCO1 PF01956.16 KXL41986.1 - 2.9 7.6 4.2 6.1 6.6 4.2 1.5 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF1682 PF07946.14 KXL41986.1 - 4.2 6.5 14.3 7 5.7 14.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Yos1 PF08571.10 KXL41987.1 - 2.7e-31 107.7 0.9 3.5e-31 107.3 0.9 1.2 1 0 0 1 1 1 1 Yos1-like Glyco_transf_22 PF03901.17 KXL41988.1 - 7.7e-36 124.2 19.4 1.1e-35 123.7 19.4 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Glyoxalase PF00903.25 KXL41989.1 - 5.6e-10 39.5 0.2 7.7e-09 35.8 0.2 2.2 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KXL41989.1 - 0.00041 20.6 0.0 0.00083 19.6 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KXL41989.1 - 0.0039 17.3 0.5 0.006 16.7 0.5 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain Phage_RpbA PF10789.9 KXL41989.1 - 0.012 15.7 0.0 0.25 11.4 0.0 2.0 2 0 0 2 2 2 0 Phage RNA polymerase binding, RpbA Glyoxalase_2 PF12681.7 KXL41989.1 - 0.015 15.2 0.0 0.22 11.4 0.0 2.1 1 1 0 1 1 1 0 Glyoxalase-like domain Pro_isomerase PF00160.21 KXL41990.1 - 5.4e-51 173.0 0.3 6.1e-51 172.8 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Glyco_hydro_17 PF00332.18 KXL41991.1 - 8.1e-05 22.4 0.1 0.013 15.1 0.2 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 PNP_UDP_1 PF01048.20 KXL41991.1 - 0.018 14.3 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Phosphorylase superfamily Metallophos PF00149.28 KXL41992.1 - 2.2e-11 44.7 0.7 3.2e-11 44.1 0.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pyr_redox_2 PF07992.14 KXL41993.1 - 4.4e-49 167.3 0.5 5.4e-49 167.0 0.5 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXL41993.1 - 1.9e-23 83.2 0.8 4.8e-20 72.0 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXL41993.1 - 3.4e-16 59.6 0.4 3.3e-14 53.2 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXL41993.1 - 8e-07 28.5 0.1 0.00012 21.4 0.0 2.3 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 KXL41993.1 - 2.3e-06 27.0 2.7 0.0025 17.0 0.3 3.6 3 1 1 4 4 4 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KXL41993.1 - 4.6e-06 26.3 1.2 7.2e-06 25.6 0.0 1.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXL41993.1 - 0.00047 20.3 0.1 0.029 14.6 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXL41993.1 - 0.00063 18.6 0.7 0.016 14.0 0.1 3.0 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.24 KXL41993.1 - 0.00069 18.8 6.9 0.028 13.5 1.4 2.7 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 KXL41993.1 - 0.00093 18.9 3.9 1.1 8.8 0.9 3.7 2 2 1 4 4 4 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KXL41993.1 - 0.0011 18.2 0.4 0.18 10.9 0.0 3.1 2 1 2 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 KXL41993.1 - 0.0022 18.4 0.7 0.037 14.5 0.0 2.8 3 1 0 3 3 3 1 Putative NAD(P)-binding Trp_halogenase PF04820.14 KXL41993.1 - 0.026 13.4 0.3 0.54 9.0 0.1 2.3 2 0 0 2 2 2 0 Tryptophan halogenase Shikimate_DH PF01488.20 KXL41993.1 - 0.059 13.4 0.3 1.4 8.9 0.0 2.9 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Attacin_N PF03768.15 KXL41993.1 - 0.1 12.7 0.2 0.27 11.4 0.2 1.6 1 0 0 1 1 1 0 Attacin, N-terminal region Atg14 PF10186.9 KXL41995.1 - 2.1e-47 161.8 2.2 2.7e-47 161.4 2.2 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 KXL41995.1 - 0.054 13.1 1.8 0.084 12.4 1.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit ThiF PF00899.21 KXL41996.1 - 6.9e-65 218.8 0.0 9.6e-65 218.3 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 KXL41996.1 - 2.1e-24 85.5 0.1 4e-24 84.6 0.1 1.4 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 KXL41996.1 - 0.0021 18.1 0.2 0.0067 16.5 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Ecm33 PF12454.8 KXL41996.1 - 0.08 13.1 1.7 0.18 11.9 1.7 1.6 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein PglD_N PF17836.1 KXL41996.1 - 0.17 12.5 0.1 0.54 10.9 0.1 1.9 1 0 0 1 1 1 0 PglD N-terminal domain Telomere_reg-2 PF10193.9 KXL41997.1 - 7.5e-33 113.2 0.0 2.8e-32 111.4 0.0 2.0 1 0 0 1 1 1 1 Telomere length regulation protein Peptidase_M1_N PF17900.1 KXL41998.1 - 1.7e-05 25.1 0.0 0.038 14.2 0.0 2.4 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain SAS4 PF15460.6 KXL41999.1 - 1.1e-33 115.3 5.7 2.4e-33 114.2 5.7 1.6 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 DUF4199 PF13858.6 KXL42001.1 - 0.0092 16.4 0.1 0.01 16.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4199) Metallophos PF00149.28 KXL42002.1 - 1.8e-09 38.4 0.0 9.7e-09 36.0 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Bac_rhamnosid_C PF17390.2 KXL42003.1 - 2.1e-11 43.4 0.0 1.1e-10 41.1 0.0 2.2 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid6H PF17389.2 KXL42003.1 - 1.7e-10 40.7 0.8 2e-08 33.9 0.6 2.1 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain MFS_1 PF07690.16 KXL42004.1 - 1.2e-21 77.0 21.6 1.2e-21 77.0 21.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL42004.1 - 1.3 7.8 15.9 0.057 12.3 6.7 2.9 3 1 0 3 3 3 0 Sugar (and other) transporter MFS_1 PF07690.16 KXL42005.1 - 4.7e-31 108.0 52.2 3.7e-30 105.0 27.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL42005.1 - 1.9e-09 36.9 3.5 1.9e-09 36.9 3.5 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 KXL42005.1 - 0.085 11.2 0.1 0.085 11.2 0.1 2.8 2 1 1 3 3 3 0 Transmembrane secretion effector PHO4 PF01384.20 KXL42005.1 - 1.7 7.6 11.1 4.1 6.3 9.7 2.2 1 1 0 1 1 1 0 Phosphate transporter family ATG22 PF11700.8 KXL42006.1 - 1.2e-64 218.7 19.1 1.7e-64 218.2 19.1 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Sec63 PF02889.16 KXL42007.1 - 3.1e-162 537.8 0.5 3e-90 301.9 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KXL42007.1 - 1.4e-43 148.7 0.0 1.7e-26 93.0 0.0 3.3 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 KXL42007.1 - 1.1e-29 102.8 0.7 4.1e-29 101.0 0.7 2.1 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 KXL42007.1 - 2.6e-20 73.1 0.0 9.3e-12 45.3 0.0 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXL42007.1 - 3.8e-10 40.1 0.0 3e-08 34.0 0.0 3.7 3 1 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KXL42007.1 - 6.1e-06 26.5 0.1 0.024 14.9 0.0 3.2 3 0 0 3 3 3 2 AAA domain T2SSE PF00437.20 KXL42007.1 - 0.0011 18.1 0.0 0.75 8.8 0.0 2.8 3 0 0 3 3 3 2 Type II/IV secretion system protein PhoH PF02562.16 KXL42007.1 - 0.0052 16.3 0.0 0.62 9.5 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein TFIIE_alpha PF02002.17 KXL42007.1 - 0.057 13.3 2.5 50 3.8 0.0 4.7 4 0 0 4 4 4 0 TFIIE alpha subunit TetR_C_37 PF18665.1 KXL42007.1 - 0.12 13.0 0.7 1.1 9.9 0.1 3.0 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain RSN1_7TM PF02714.15 KXL42011.1 - 1.5e-82 277.0 13.5 1.5e-82 277.0 13.5 1.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KXL42011.1 - 8.1e-39 132.9 1.2 8.1e-39 132.9 1.2 2.7 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KXL42011.1 - 5.5e-21 75.6 0.0 7.8e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KXL42011.1 - 2.6e-17 62.7 0.0 5.7e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter 7tm_1 PF00001.21 KXL42011.1 - 0.0087 15.4 0.0 0.14 11.5 0.0 2.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2834 PF11196.8 KXL42011.1 - 0.018 15.4 0.2 0.078 13.3 0.2 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2834) COX7C PF02935.16 KXL42011.1 - 4.7 7.5 5.9 6.5 7.1 0.3 2.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc AAA PF00004.29 KXL42012.1 - 7.4e-55 185.0 0.0 1.9e-42 144.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 KXL42012.1 - 6.6e-28 96.9 0.4 1.3e-27 96.0 0.4 1.5 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 KXL42012.1 - 2.1e-13 49.8 0.5 8.1e-08 32.0 0.1 3.0 2 1 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KXL42012.1 - 5e-10 40.0 3.0 0.00046 20.6 0.1 3.9 2 2 0 3 3 3 2 AAA ATPase domain NACHT PF05729.12 KXL42012.1 - 7.6e-08 32.4 0.3 5.9e-05 23.0 0.0 3.1 3 0 0 3 3 3 1 NACHT domain AAA_2 PF07724.14 KXL42012.1 - 1e-06 29.0 0.0 0.0061 16.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KXL42012.1 - 2.4e-06 27.4 0.0 0.013 15.2 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KXL42012.1 - 8.2e-06 25.5 0.0 0.00045 19.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region TsaE PF02367.17 KXL42012.1 - 3.8e-05 23.7 0.2 0.081 12.9 0.1 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 KXL42012.1 - 0.0001 22.3 0.1 0.49 10.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXL42012.1 - 0.00023 21.5 2.7 0.94 9.8 0.0 4.1 3 2 2 5 5 5 2 AAA domain PEX-2N PF09263.10 KXL42012.1 - 0.00024 21.4 1.1 0.094 13.0 0.0 3.4 3 0 0 3 3 3 1 Peroxisome biogenesis factor 1, N-terminal TIP49 PF06068.13 KXL42012.1 - 0.00026 20.3 0.1 0.43 9.7 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain Sigma54_activat PF00158.26 KXL42012.1 - 0.00029 20.6 0.0 0.021 14.6 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.6 KXL42012.1 - 0.00059 20.4 0.1 1.6 9.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KXL42012.1 - 0.001 18.4 0.0 0.32 10.3 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_14 PF13173.6 KXL42012.1 - 0.0021 18.1 0.0 2.7 8.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KXL42012.1 - 0.003 17.2 1.0 1.3 8.6 0.0 3.8 3 1 1 4 4 4 1 AAA domain NB-ARC PF00931.22 KXL42012.1 - 0.0035 16.6 0.2 0.78 8.9 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_33 PF13671.6 KXL42012.1 - 0.0042 17.2 0.0 0.23 11.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KXL42012.1 - 0.0069 15.6 0.0 0.1 11.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 KXL42012.1 - 0.0079 15.9 0.1 4.3 7.0 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 KXL42012.1 - 0.0085 16.2 0.0 0.57 10.3 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain KAP_NTPase PF07693.14 KXL42012.1 - 0.0094 15.2 1.0 0.38 10.0 0.1 2.5 1 1 1 2 2 2 1 KAP family P-loop domain Mg_chelatase PF01078.21 KXL42012.1 - 0.0094 15.3 0.2 0.78 9.1 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 KXL42012.1 - 0.012 15.0 0.2 2.5 7.4 0.1 2.3 2 0 0 2 2 2 0 KaiC AAA_28 PF13521.6 KXL42012.1 - 0.023 14.9 0.1 17 5.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 KXL42012.1 - 0.036 14.0 0.1 0.49 10.3 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_17 PF13207.6 KXL42012.1 - 0.042 14.3 0.1 2.4 8.6 0.1 2.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KXL42012.1 - 0.043 14.3 0.0 14 6.2 0.0 2.6 2 0 0 2 2 2 0 ABC transporter APS_kinase PF01583.20 KXL42012.1 - 0.069 13.1 0.1 0.29 11.0 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_19 PF13245.6 KXL42012.1 - 0.084 13.2 0.1 1.2 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 KXL42012.1 - 0.11 12.6 0.0 30 4.7 0.0 2.9 3 0 0 3 3 2 0 Shikimate kinase AAA_29 PF13555.6 KXL42012.1 - 0.12 12.2 0.6 1.5 8.6 0.7 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain CoaE PF01121.20 KXL42012.1 - 0.12 12.0 0.1 0.31 10.7 0.1 1.7 1 0 0 1 1 1 0 Dephospho-CoA kinase RNA_helicase PF00910.22 KXL42012.1 - 0.13 12.7 0.0 5 7.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_11 PF13086.6 KXL42012.1 - 0.17 11.7 2.0 5.6 6.7 0.7 2.9 3 1 0 3 3 3 0 AAA domain DUF2075 PF09848.9 KXL42012.1 - 0.21 10.8 0.0 9.2 5.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) C2 PF00168.30 KXL42013.1 - 4.2e-13 49.5 0.0 7.3e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain Med7 PF05983.11 KXL42014.1 - 0.014 15.5 0.2 0.026 14.6 0.2 1.3 1 0 0 1 1 1 0 MED7 protein DUF1981 PF09324.10 KXL42014.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1981) Zn_clus PF00172.18 KXL42014.1 - 1.8 8.8 6.1 4 7.6 6.1 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Troponin-I_N PF11636.8 KXL42014.1 - 6.6 6.8 9.5 6.9 6.7 6.4 2.5 2 0 0 2 2 2 0 Troponin I residues 1-32 C2 PF00168.30 KXL42015.1 - 1.6e-22 79.7 0.0 8.8e-11 42.0 0.0 2.6 2 0 0 2 2 2 2 C2 domain SMP_LBD PF17047.5 KXL42015.1 - 0.18 11.3 0.0 5.5 6.4 0.0 2.3 2 0 0 2 2 2 0 Synaptotagmin-like mitochondrial-lipid-binding domain Thioredoxin_7 PF13899.6 KXL42016.1 - 4.4e-17 62.0 0.0 8.5e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 KXL42016.1 - 4.4e-12 45.6 0.4 1.2e-11 44.3 0.4 1.7 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KXL42016.1 - 3.9e-05 23.8 0.0 7.4e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 UBX domain Thioredoxin_2 PF13098.6 KXL42016.1 - 0.0041 17.6 0.0 0.009 16.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain DUF2744 PF10910.8 KXL42016.1 - 0.061 13.3 0.2 0.15 12.0 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2744) RAP80_UIM PF18282.1 KXL42016.1 - 0.073 12.9 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 RAP80 N-terminal ubiquitin interaction motif Thioredox_DsbH PF03190.15 KXL42016.1 - 0.077 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Proteasome PF00227.26 KXL42018.1 - 1.2e-47 161.9 4.5 4.4e-33 114.4 0.0 2.5 2 1 1 3 3 3 2 Proteasome subunit Proteasome_A_N PF10584.9 KXL42018.1 - 5.7e-12 45.1 1.0 6.2e-12 45.0 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Pex14_N PF04695.13 KXL42019.1 - 1.5e-27 97.2 0.6 1.5e-27 97.2 0.6 2.9 2 2 2 4 4 4 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Enkurin PF13864.6 KXL42019.1 - 0.26 11.7 6.7 7.3 7.1 0.4 2.8 2 1 0 2 2 2 0 Calmodulin-binding PAPA-1 PF04795.12 KXL42020.1 - 1.5e-31 109.0 4.5 1.5e-31 109.0 4.5 3.5 2 1 0 2 2 2 1 PAPA-1-like conserved region VSG_B PF13206.6 KXL42020.1 - 2.1 7.5 7.3 0.54 9.5 0.8 2.1 2 0 0 2 2 2 0 Trypanosomal VSG domain TP2 PF01254.18 KXL42020.1 - 9.2 6.9 15.5 2.3 8.8 6.2 2.3 2 0 0 2 2 2 0 Nuclear transition protein 2 Toxin_6 PF05453.12 KXL42022.1 - 0.0065 16.9 3.0 0.015 15.7 3.0 1.6 1 0 0 1 1 1 1 BmTXKS1/BmP02 toxin family Macoilin PF09726.9 KXL42022.1 - 3.3 6.1 9.3 4.2 5.8 9.3 1.1 1 0 0 1 1 1 0 Macoilin family RAP1 PF07218.11 KXL42022.1 - 8.6 4.5 15.3 11 4.2 15.3 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CN_hydrolase PF00795.22 KXL42023.1 - 2.1e-30 106.0 0.0 2.9e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 KXL42023.1 - 6e-23 81.2 0.0 3e-22 78.9 0.0 2.0 1 1 0 1 1 1 1 NAD synthase RhoGEF PF00621.20 KXL42024.1 - 3.2e-37 128.5 0.3 1.2e-36 126.6 0.1 2.0 2 0 0 2 2 2 1 RhoGEF domain BAR PF03114.18 KXL42024.1 - 1.2e-13 51.2 0.1 1.2e-13 51.2 0.1 2.7 3 0 0 3 3 3 1 BAR domain Trp_repressor PF01371.19 KXL42024.1 - 0.11 12.7 0.1 1.4 9.1 0.0 2.5 2 0 0 2 2 2 0 Trp repressor protein Tannase PF07519.11 KXL42025.1 - 1.1e-105 354.3 0.3 1.2e-105 354.1 0.3 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase WD40 PF00400.32 KXL42026.1 - 1.8e-24 85.5 6.1 2.3e-06 28.2 0.0 5.9 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL42026.1 - 0.0034 17.6 0.0 0.17 12.2 0.0 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KXL42026.1 - 0.011 15.1 0.0 0.26 10.5 0.0 2.3 1 1 0 2 2 2 0 WD40-like domain Nup160 PF11715.8 KXL42026.1 - 0.056 12.1 0.2 0.39 9.3 0.1 2.3 1 1 1 2 2 2 0 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KXL42026.1 - 0.17 12.4 2.0 52 4.5 0.1 4.3 4 0 0 4 4 4 0 PQQ-like domain RhoGAP PF00620.27 KXL42027.1 - 4e-16 59.2 0.0 9.4e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain DEP PF00610.21 KXL42027.1 - 2.6e-11 43.4 0.0 5.2e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 KXL42027.1 - 6.2e-10 39.2 0.0 1.5e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain DUF3385 PF11865.8 KXL42027.1 - 0.11 12.4 0.4 0.34 10.8 0.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) YTH PF04146.15 KXL42028.1 - 2.8e-60 203.0 0.0 7.8e-60 201.6 0.0 1.8 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 KXL42028.1 - 1.3e-06 28.1 0.0 2.3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PI3_PI4_kinase PF00454.27 KXL42029.1 - 3.7e-38 131.8 0.0 9.2e-36 123.9 0.0 2.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KXL42029.1 - 1.3e-26 93.1 1.2 7.9e-26 90.6 0.0 2.7 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF2408 PF10303.9 KXL42029.1 - 0.077 13.6 0.0 0.33 11.5 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DIOX_N PF14226.6 KXL42031.1 - 3.8e-12 47.0 0.0 6e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXL42031.1 - 8.1e-08 32.7 0.0 1.3e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.17 KXL42032.1 - 1.3e-13 49.9 0.2 0.00063 19.7 0.3 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXL42032.1 - 5e-13 48.3 1.6 4.2e-05 23.2 0.7 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat F-box-like PF12937.7 KXL42032.1 - 4.8e-10 39.2 0.6 1.1e-09 38.0 0.6 1.7 1 0 0 1 1 1 1 F-box-like TPR_8 PF13181.6 KXL42032.1 - 2.2e-09 36.8 0.0 0.16 12.2 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXL42032.1 - 3.1e-07 30.6 0.2 0.45 11.5 0.2 4.1 2 1 2 4 4 4 2 Tetratricopeptide repeat F-box PF00646.33 KXL42032.1 - 3.3e-07 30.0 0.3 8.6e-07 28.7 0.3 1.8 1 0 0 1 1 1 1 F-box domain TPR_11 PF13414.6 KXL42032.1 - 4.2e-07 29.5 0.0 0.0014 18.2 0.0 2.8 3 0 0 3 3 3 2 TPR repeat TPR_12 PF13424.6 KXL42032.1 - 1e-06 28.9 0.4 0.015 15.6 0.5 3.9 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 KXL42032.1 - 9.7e-06 25.9 1.9 0.12 13.0 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXL42032.1 - 8.6e-05 22.6 0.0 0.0021 18.2 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXL42032.1 - 0.00012 22.7 0.1 1.1 10.0 0.0 2.7 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXL42032.1 - 0.0004 20.2 0.3 3.2 8.0 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat LRR_6 PF13516.6 KXL42032.1 - 0.0011 18.9 7.3 0.8 9.9 0.0 5.5 5 0 0 5 5 5 1 Leucine Rich repeat TPR_19 PF14559.6 KXL42032.1 - 0.0045 17.5 0.2 0.81 10.2 0.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_3 PF07720.12 KXL42032.1 - 0.013 15.5 0.0 0.041 13.9 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat LRR_8 PF13855.6 KXL42032.1 - 0.015 15.0 11.2 2.9 7.7 0.0 5.7 3 2 1 5 5 5 0 Leucine rich repeat DUF3760 PF12586.8 KXL42032.1 - 0.029 14.5 0.2 11 6.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3760) SPO22 PF08631.10 KXL42032.1 - 0.042 13.3 0.0 0.076 12.5 0.0 1.5 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like ANAPC3 PF12895.7 KXL42032.1 - 0.063 13.5 0.2 0.56 10.5 0.1 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 LRR_1 PF00560.33 KXL42032.1 - 0.071 13.7 1.6 2.6e+02 2.8 0.0 6.0 5 1 0 5 5 4 0 Leucine Rich Repeat LRR_4 PF12799.7 KXL42032.1 - 0.083 13.4 15.9 23 5.6 2.9 6.4 5 2 3 8 8 7 0 Leucine Rich repeats (2 copies) Evr1_Alr PF04777.13 KXL42033.1 - 1.7e-27 95.8 0.0 2.2e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Erv1 / Alr family APOBEC1 PF18769.1 KXL42033.1 - 0.049 13.9 0.1 0.064 13.5 0.1 1.2 1 0 0 1 1 1 0 APOBEC1 SNAD4 PF18750.1 KXL42033.1 - 0.052 13.7 0.0 0.06 13.5 0.0 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 Aminotran_4 PF01063.19 KXL42034.1 - 1.2e-24 87.4 0.0 1.7e-24 87.0 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Abhydrolase_1 PF00561.20 KXL42035.1 - 6.2e-13 49.0 0.0 4.2e-11 43.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2048 PF09752.9 KXL42035.1 - 0.041 13.0 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 IDO PF01231.18 KXL42037.1 - 5e-40 137.6 0.0 6.7e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase GFA PF04828.14 KXL42039.1 - 1.4e-19 70.2 0.0 2.1e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.11 KXL42039.1 - 0.065 12.9 0.5 0.065 12.9 0.5 2.6 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Securin PF04856.13 KXL42040.1 - 0.014 15.4 3.0 0.016 15.2 1.4 1.9 2 1 0 2 2 2 0 Securin sister-chromatid separation inhibitor Med3 PF11593.8 KXL42040.1 - 0.27 10.4 14.1 0.41 9.8 14.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Tropomyosin_1 PF12718.7 KXL42041.1 - 3e-50 170.1 37.9 3.5e-50 169.9 37.9 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 KXL42041.1 - 9.3e-07 28.5 35.7 9.8e-05 21.8 20.1 2.8 1 1 1 2 2 2 2 Tropomyosin Laminin_II PF06009.12 KXL42041.1 - 0.00073 19.6 5.6 0.00073 19.6 5.6 2.1 1 1 1 2 2 2 1 Laminin Domain II bZIP_1 PF00170.21 KXL42041.1 - 0.0024 17.9 33.1 0.077 13.1 6.0 4.8 2 1 3 5 5 5 3 bZIP transcription factor DUF724 PF05266.14 KXL42041.1 - 0.0038 17.1 27.0 0.099 12.5 7.7 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF724) CENP-F_leu_zip PF10473.9 KXL42041.1 - 0.0058 16.7 3.6 0.0058 16.7 3.6 3.0 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Uso1_p115_C PF04871.13 KXL42041.1 - 0.006 16.9 40.5 0.009 16.4 15.8 2.1 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region TMF_TATA_bd PF12325.8 KXL42041.1 - 0.0061 16.8 29.4 0.01 16.0 19.1 2.2 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 KXL42041.1 - 0.0084 16.2 17.7 0.028 14.5 3.1 2.7 1 1 2 3 3 3 1 Protein of unknown function (DUF1664) ERM PF00769.19 KXL42041.1 - 0.012 15.4 16.2 0.012 15.4 16.2 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family TMF_DNA_bd PF12329.8 KXL42041.1 - 0.012 15.6 15.0 0.012 15.6 15.0 3.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 KXL42041.1 - 0.013 15.8 33.2 0.16 12.2 12.7 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) GAS PF13851.6 KXL42041.1 - 0.017 14.5 35.7 0.035 13.5 35.7 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding HMMR_C PF15908.5 KXL42041.1 - 0.032 14.5 20.6 0.077 13.3 3.8 2.5 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal KLRAQ PF10205.9 KXL42041.1 - 0.048 13.9 25.3 0.047 13.9 11.0 2.8 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Cortex-I_coil PF09304.10 KXL42041.1 - 0.05 13.8 28.3 1.6 9.0 11.3 3.1 1 1 2 3 3 3 0 Cortexillin I, coiled coil ADIP PF11559.8 KXL42041.1 - 0.06 13.4 31.1 0.37 10.9 13.7 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Seryl_tRNA_N PF02403.22 KXL42041.1 - 0.08 13.2 26.6 0.34 11.2 2.3 2.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 KXL42041.1 - 0.11 13.0 41.2 0.43 11.1 15.3 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region Lectin_N PF03954.14 KXL42041.1 - 0.12 12.1 12.6 0.078 12.7 1.7 2.3 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Swi5 PF07061.11 KXL42041.1 - 0.14 12.3 25.1 0.2 11.8 6.9 3.4 2 1 1 3 3 3 0 Swi5 Spc7 PF08317.11 KXL42041.1 - 0.17 10.7 35.0 1.2 8.0 13.9 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Fmp27_WPPW PF10359.9 KXL42041.1 - 0.17 10.7 27.5 0.45 9.3 9.6 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain FlaC_arch PF05377.11 KXL42041.1 - 0.19 12.2 22.2 1.1 9.7 6.7 4.2 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF3450 PF11932.8 KXL42041.1 - 0.19 11.0 31.2 0.67 9.2 13.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) BLOC1_2 PF10046.9 KXL42041.1 - 0.25 11.7 24.9 6.8 7.1 8.4 3.5 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HrpB7 PF09486.10 KXL42041.1 - 0.26 11.7 23.5 0.41 11.0 23.5 1.4 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) TACC_C PF05010.14 KXL42041.1 - 0.27 11.0 29.2 1.1 9.0 26.5 2.3 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Jnk-SapK_ap_N PF09744.9 KXL42041.1 - 0.28 11.4 34.5 0.26 11.5 14.7 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 HAP1_N PF04849.13 KXL42041.1 - 0.3 10.3 30.3 1.3 8.2 16.4 2.2 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Taxilin PF09728.9 KXL42041.1 - 0.44 9.7 34.1 0.8 8.8 13.3 2.1 1 1 1 2 2 2 0 Myosin-like coiled-coil protein DUF812 PF05667.11 KXL42041.1 - 0.96 8.2 34.6 2 7.2 34.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) CR6_interact PF10147.9 KXL42041.1 - 1 9.0 30.6 0.15 11.8 15.1 2.1 1 1 1 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DHR10 PF18595.1 KXL42041.1 - 1.3 9.1 39.8 3.8 7.6 17.2 3.0 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain DUF3584 PF12128.8 KXL42041.1 - 1.3 6.4 29.4 1.6 6.2 29.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GIT_CC PF16559.5 KXL42041.1 - 1.5 8.8 18.4 1.8 8.5 6.7 3.4 3 1 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor HOOK PF05622.12 KXL42041.1 - 1.5 6.9 32.0 2.6 6.1 32.0 1.4 1 1 0 1 1 1 0 HOOK protein MCC-bdg_PDZ PF10506.9 KXL42041.1 - 1.5 8.9 17.5 2.2 8.3 4.6 3.0 2 1 1 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Leu_zip PF15294.6 KXL42041.1 - 1.6 8.2 25.3 1.9 7.9 25.3 1.1 1 0 0 1 1 1 0 Leucine zipper VGPC1_C PF16799.5 KXL42041.1 - 1.6 8.8 12.0 0.38 10.8 2.0 3.3 2 2 1 3 3 3 0 C-terminal membrane-localisation domain of ion-channel, VCN1 Nup88 PF10168.9 KXL42041.1 - 1.7 6.4 24.2 1.9 6.2 24.2 1.1 1 0 0 1 1 1 0 Nuclear pore component Mod_r PF07200.13 KXL42041.1 - 1.8 8.7 30.2 0.53 10.4 2.2 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TANGO2 PF05742.12 KXL42041.1 - 2.2 8.2 10.9 2.5 8.1 9.8 1.7 1 1 1 2 2 2 0 Transport and Golgi organisation 2 SOGA PF11365.8 KXL42041.1 - 2.4 9.4 26.3 3.6 8.8 7.9 3.1 2 1 1 3 3 3 0 Protein SOGA DUF4201 PF13870.6 KXL42041.1 - 2.5 7.8 29.4 1.2 8.9 11.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) KASH_CCD PF14662.6 KXL42041.1 - 2.6 7.8 33.9 2.6 7.8 12.2 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH HMMR_N PF15905.5 KXL42041.1 - 2.6 7.4 33.6 4.8 6.6 33.6 1.5 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal BRE1 PF08647.11 KXL42041.1 - 2.6 8.2 36.7 2.1 8.5 21.7 2.5 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase PI3K_P85_iSH2 PF16454.5 KXL42041.1 - 3.2 7.3 30.7 4.9 6.7 24.0 2.1 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Fib_alpha PF08702.10 KXL42041.1 - 3.3 7.9 19.5 2.4 8.3 4.6 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 KXL42041.1 - 3.5 7.7 33.4 6.2 6.9 14.1 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF948 PF06103.11 KXL42041.1 - 3.8 7.8 12.9 9.7 6.5 2.7 3.0 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HAUS-augmin3 PF14932.6 KXL42041.1 - 3.9 7.0 30.6 1.6 8.2 2.6 2.7 1 1 2 3 3 3 0 HAUS augmin-like complex subunit 3 Fez1 PF06818.15 KXL42041.1 - 4.6 7.7 30.3 44 4.5 28.7 2.0 1 1 0 1 1 1 0 Fez1 Lebercilin PF15619.6 KXL42041.1 - 4.7 6.8 34.3 80 2.8 34.2 2.3 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease TPR_MLP1_2 PF07926.12 KXL42041.1 - 5.3 7.1 40.2 4.9 7.2 11.2 3.0 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Sec34 PF04136.15 KXL42041.1 - 6.2 6.7 17.3 1.7 8.6 3.1 2.1 1 1 1 2 2 2 0 Sec34-like family CENP-H PF05837.12 KXL42041.1 - 7.2 7.1 29.6 1.5 9.2 14.2 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) FUSC PF04632.12 KXL42041.1 - 8.4 4.8 10.0 10 4.5 10.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family IFT46_B_C PF12317.8 KXL42041.1 - 8.4 6.1 14.4 0.25 11.0 4.3 2.0 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal CbiX PF01903.17 KXL42041.1 - 8.4 6.8 7.8 23 5.4 0.9 2.4 2 1 0 2 2 2 0 CbiX ZapB PF06005.12 KXL42041.1 - 8.5 6.9 40.9 3.7 8.1 6.8 3.9 1 1 3 4 4 4 0 Cell division protein ZapB Transketolase_N PF00456.21 KXL42041.1 - 8.7 5.2 9.2 0.84 8.5 4.0 1.8 1 1 1 2 2 2 0 Transketolase, thiamine diphosphate binding domain DUF4200 PF13863.6 KXL42041.1 - 9.7 6.6 36.7 5.9 7.3 16.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) SlyX PF04102.12 KXL42041.1 - 9.9 6.9 25.1 1 10.0 5.7 3.8 1 1 3 4 4 4 0 SlyX Nop25 PF09805.9 KXL42042.1 - 6.1e-32 110.9 17.3 6.1e-32 110.9 17.3 2.2 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) HisG PF01634.18 KXL42043.1 - 1e-52 178.4 0.0 1.4e-52 177.9 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 KXL42043.1 - 6.4e-28 96.7 0.2 1.3e-27 95.7 0.2 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 KXL42043.1 - 0.0056 16.6 0.0 0.8 9.6 0.0 2.3 2 0 0 2 2 2 2 NMT1/THI5 like Zn_clus PF00172.18 KXL42044.1 - 6.4e-08 32.6 9.6 6.4e-08 32.6 9.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MARVEL PF01284.23 KXL42045.1 - 7.5e-05 22.8 13.8 0.00012 22.1 13.8 1.3 1 1 0 1 1 1 1 Membrane-associating domain APG9 PF04109.16 KXL42045.1 - 0.17 10.9 5.1 0.027 13.5 1.7 1.3 2 0 0 2 2 2 0 Autophagy protein Apg9 Glyco_transf_28 PF03033.20 KXL42046.1 - 2.4e-20 73.0 0.0 4.5e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KXL42046.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase IL12p40_C PF10420.9 KXL42046.1 - 0.31 11.6 1.0 0.7 10.4 1.0 1.5 1 0 0 1 1 1 0 Cytokine interleukin-12p40 C-terminus Na_Ca_ex PF01699.24 KXL42047.1 - 5.9e-47 159.4 47.3 1.8e-29 102.7 17.3 3.1 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Cnd2 PF05786.14 KXL42048.1 - 6.6e-236 785.6 0.1 8.6e-236 785.3 0.1 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 KXL42048.1 - 0.066 13.4 0.1 0.24 11.6 0.0 1.9 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal UQ_con PF00179.26 KXL42050.1 - 5.9e-52 175.1 0.0 6.6e-52 174.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXL42050.1 - 0.0024 17.6 0.0 0.0029 17.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KXL42050.1 - 0.037 14.3 0.0 0.045 14.0 0.0 1.2 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 KXL42050.1 - 0.046 13.6 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain WSC PF01822.19 KXL42051.1 - 6.2e-08 32.7 2.3 8.9e-08 32.2 2.3 1.2 1 0 0 1 1 1 1 WSC domain Pkinase PF00069.25 KXL42053.1 - 2.6e-13 50.0 0.2 1.3e-05 24.7 0.0 4.8 3 2 1 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXL42053.1 - 0.0089 15.3 0.0 1 8.6 0.0 3.1 3 1 1 4 4 4 1 Protein tyrosine kinase ODC_AZ PF02100.17 KXL42054.1 - 2.3e-15 56.6 0.1 3.2e-15 56.1 0.1 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme KilA-N PF04383.13 KXL42055.1 - 3.3e-05 23.7 0.0 0.00067 19.5 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain DDHD PF02862.17 KXL42056.1 - 8.7e-61 205.9 0.0 8.7e-61 205.9 0.0 2.8 3 1 0 3 3 3 1 DDHD domain DUF676 PF05057.14 KXL42056.1 - 0.084 12.4 0.1 0.24 10.9 0.0 1.7 2 0 0 2 2 2 0 Putative serine esterase (DUF676) zf-RING_2 PF13639.6 KXL42057.1 - 0.0013 19.1 2.0 0.0013 19.1 2.0 2.0 2 0 0 2 2 2 1 Ring finger domain zf-ribbon_3 PF13248.6 KXL42057.1 - 0.021 14.2 2.4 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Nudix_N_2 PF14803.6 KXL42057.1 - 0.34 10.9 3.1 1.8 8.6 0.1 2.7 2 0 0 2 2 2 0 Nudix N-terminal Gmx_para_CXXCG PF09535.10 KXL42057.1 - 0.36 10.0 1.4 0.39 10.0 0.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (Gmx_para_CXXCG) zf-C3HC4_2 PF13923.6 KXL42057.1 - 0.64 9.9 6.6 0.36 10.7 2.8 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_2 PF13240.6 KXL42057.1 - 1.2 8.9 7.8 3.5 7.5 0.3 2.8 3 0 0 3 3 3 0 zinc-ribbon domain MSC PF09402.10 KXL42058.1 - 3.1e-101 339.2 0.0 5.4e-101 338.4 0.0 1.4 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 KXL42058.1 - 1.2e-15 56.9 1.1 1.9e-15 56.3 0.0 2.0 2 0 0 2 2 2 1 HeH/LEM domain Thymopoietin PF08198.11 KXL42058.1 - 0.00096 18.7 0.0 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 Thymopoietin protein Endonuc-dimeris PF09124.10 KXL42058.1 - 0.084 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 T4 recombination endonuclease VII, dimerisation Ribosomal_L44 PF00935.19 KXL42059.1 - 6.8e-37 125.8 12.0 1.1e-36 125.2 12.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 DUF1115 PF06544.12 KXL42060.1 - 0.0013 18.8 0.0 0.0026 17.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RWD PF05773.22 KXL42060.1 - 0.0039 17.5 0.4 0.027 14.7 0.4 2.3 1 1 0 1 1 1 1 RWD domain Pkinase PF00069.25 KXL42064.1 - 1.1e-67 228.1 0.0 1.4e-67 227.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL42064.1 - 1e-32 113.5 0.0 1.3e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXL42064.1 - 0.00033 20.1 0.4 0.00061 19.2 0.4 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXL42064.1 - 0.0056 15.7 0.4 0.016 14.2 0.4 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KXL42064.1 - 0.006 15.9 0.0 0.0094 15.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXL42064.1 - 0.035 14.0 0.2 0.081 12.8 0.2 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KXL42064.1 - 0.048 12.7 0.1 0.071 12.2 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Yippee-Mis18 PF03226.14 KXL42065.1 - 8.8e-23 80.5 0.0 1.3e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 KXL42065.1 - 0.014 15.6 0.3 0.046 14.0 0.0 1.8 2 0 0 2 2 2 0 C-terminal domain of RIG-I HECT_2 PF09814.9 KXL42065.1 - 0.019 13.9 0.1 1.3 7.8 0.0 2.1 2 0 0 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding zf-ribbon_3 PF13248.6 KXL42065.1 - 0.023 14.1 0.1 0.061 12.8 0.1 1.8 1 0 0 1 1 1 0 zinc-ribbon domain DWNN PF08783.11 KXL42066.1 - 3.2e-27 94.6 0.2 1.2e-26 92.8 0.0 2.0 2 0 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.6 KXL42066.1 - 4.2e-11 42.4 6.4 9.3e-11 41.3 6.4 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KXL42066.1 - 0.0019 18.2 2.8 0.0019 18.2 2.8 2.1 3 0 0 3 3 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 KXL42066.1 - 0.024 14.6 0.7 0.024 14.6 0.7 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-RING_2 PF13639.6 KXL42066.1 - 0.027 14.8 7.6 0.027 14.8 7.6 1.7 2 0 0 2 2 2 0 Ring finger domain zf-RING_UBOX PF13445.6 KXL42066.1 - 0.063 13.3 7.8 0.13 12.3 7.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-Nse PF11789.8 KXL42066.1 - 0.071 12.9 5.1 0.14 12.0 5.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Rtf2 PF04641.12 KXL42066.1 - 0.27 10.5 11.3 0.55 9.5 11.3 1.5 1 1 0 1 1 1 0 Rtf2 RING-finger zf-C3HC4 PF00097.25 KXL42066.1 - 1.4 8.8 8.9 3.3 7.7 8.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXL42066.1 - 1.6 9.0 9.3 3.6 7.8 9.3 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zinc-ribbons_6 PF07191.12 KXL42066.1 - 2.2 8.3 8.0 24 5.0 4.3 2.3 2 0 0 2 2 2 0 zinc-ribbons DUF1272 PF06906.11 KXL42066.1 - 2.3 8.4 10.4 0.3 11.2 4.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-C3HC4_2 PF13923.6 KXL42066.1 - 3.4 7.6 16.3 0.073 12.9 8.8 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXL42066.1 - 4.5 7.3 13.1 0.35 10.8 6.7 2.1 2 0 0 2 2 2 0 zinc-RING finger domain MGC-24 PF05283.11 KXL42066.1 - 5.2 7.5 6.9 19 5.7 6.9 2.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Ribophorin_I PF04597.14 KXL42067.1 - 1.3e-150 502.5 0.5 1.4e-150 502.3 0.5 1.0 1 0 0 1 1 1 1 Ribophorin I Indigoidine_A PF04227.12 KXL42068.1 - 5.4e-119 396.9 0.1 9.1e-119 396.1 0.1 1.4 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 KXL42068.1 - 5.8e-19 68.5 0.4 3.7e-10 39.6 0.0 2.5 2 1 0 2 2 2 2 pfkB family carbohydrate kinase DRIM PF07539.12 KXL42069.1 - 1e-157 526.2 10.0 1e-157 526.2 10.0 5.5 5 3 1 6 6 6 1 Down-regulated in metastasis CLASP_N PF12348.8 KXL42069.1 - 0.068 12.7 11.7 0.029 13.9 0.7 5.3 5 1 0 5 5 5 0 CLASP N terminal Nipped-B_C PF12830.7 KXL42069.1 - 0.08 12.9 2.0 8.2 6.3 0.6 3.8 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus DUF647 PF04884.14 KXL42069.1 - 0.14 11.8 2.1 0.47 10.0 0.0 2.9 3 0 0 3 3 3 0 Vitamin B6 photo-protection and homoeostasis V-ATPase_H_C PF11698.8 KXL42069.1 - 2 8.5 6.5 28 4.9 0.0 5.4 6 0 0 6 6 6 0 V-ATPase subunit H CwfJ_C_1 PF04677.15 KXL42070.1 - 2.9e-21 75.6 0.0 4.9e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 KXL42070.1 - 8.6e-14 52.2 1.3 1.8e-13 51.2 1.3 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 PGM_PMM_I PF02878.16 KXL42071.1 - 3e-38 130.7 0.1 1.4e-37 128.5 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 KXL42071.1 - 1.6e-18 67.2 0.0 3.7e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KXL42071.1 - 7.8e-14 51.8 0.0 1.4e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 KXL42071.1 - 1.7e-06 28.1 0.0 6.7e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Beta-lactamase PF00144.24 KXL42072.1 - 1.6e-12 47.4 0.0 1.8e-12 47.2 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase DUF1664 PF07889.12 KXL42073.1 - 0.00059 19.9 6.9 0.00059 19.9 6.9 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1664) ERM PF00769.19 KXL42073.1 - 0.0015 18.4 47.2 0.0015 18.4 47.2 2.8 2 1 1 3 3 3 1 Ezrin/radixin/moesin family ATG16 PF08614.11 KXL42073.1 - 0.0059 16.9 19.4 0.0059 16.9 19.4 4.5 2 2 3 5 5 5 1 Autophagy protein 16 (ATG16) Laminin_II PF06009.12 KXL42073.1 - 0.0064 16.5 11.4 0.0064 16.5 11.4 2.7 3 1 1 4 4 3 1 Laminin Domain II AAA_13 PF13166.6 KXL42073.1 - 0.013 14.2 9.4 0.026 13.2 9.4 1.5 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.8 KXL42073.1 - 0.085 10.4 27.8 0.2 9.1 27.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MAD PF05557.13 KXL42073.1 - 1.4 7.2 39.6 0.2 10.0 24.8 2.9 3 0 0 3 3 3 0 Mitotic checkpoint protein Borrelia_P83 PF05262.11 KXL42073.1 - 1.4 7.3 20.2 2.5 6.5 20.2 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein T3SSipB PF16535.5 KXL42073.1 - 1.6 9.2 18.3 5.7 7.4 18.3 1.9 1 0 0 1 1 1 0 Type III cell invasion protein SipB ISG65-75 PF11727.8 KXL42073.1 - 1.8 7.7 16.8 0.087 12.0 9.6 2.2 1 1 1 2 2 2 0 Invariant surface glycoprotein Sec34 PF04136.15 KXL42073.1 - 2.2 8.2 14.9 9.9 6.0 0.2 2.9 2 1 0 2 2 2 0 Sec34-like family DUF87 PF01935.17 KXL42073.1 - 2.7 8.0 5.2 7.6 6.6 5.2 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain Asp-B-Hydro_N PF05279.11 KXL42073.1 - 3.7 7.6 16.3 7.4 6.6 16.3 1.6 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region V_ATPase_I PF01496.19 KXL42073.1 - 5.5 4.8 18.3 5.8 4.7 16.2 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family NPV_P10 PF05531.12 KXL42073.1 - 6.2 7.4 11.3 6.5 7.3 3.2 3.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Hamartin PF04388.12 KXL42073.1 - 8.8 4.9 21.2 15 4.1 21.2 1.4 1 0 0 1 1 1 0 Hamartin protein Baculo_F PF12259.8 KXL42073.1 - 9.1 4.7 5.7 2.5 6.5 2.2 1.7 2 0 0 2 2 2 0 Baculovirus F protein Exo_endo_phos_2 PF14529.6 KXL42074.1 - 0.0012 18.7 0.3 0.0052 16.6 0.0 1.9 1 1 1 2 2 2 1 Endonuclease-reverse transcriptase PAS_11 PF14598.6 KXL42074.1 - 0.072 13.2 0.0 0.17 12.1 0.0 1.5 2 0 0 2 2 2 0 PAS domain Ligase_CoA PF00549.19 KXL42078.1 - 8.1e-36 123.1 2.6 1.4e-18 67.2 0.5 2.5 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.19 KXL42078.1 - 1.3e-15 57.8 0.1 4.2e-15 56.2 0.1 1.9 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.6 KXL42078.1 - 1.4e-11 44.3 0.1 8.2e-09 35.4 0.0 2.6 2 0 0 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain Rad60-SLD PF11976.8 KXL42079.1 - 2.8e-18 65.5 0.1 3.3e-18 65.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KXL42079.1 - 6.8e-10 38.6 0.0 7.7e-10 38.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family MTCP1 PF08991.10 KXL42080.1 - 4.2e-30 103.8 10.1 4.9e-30 103.6 10.1 1.1 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 KXL42080.1 - 0.0008 19.5 8.9 0.0013 18.8 8.9 1.4 1 0 0 1 1 1 1 CHCH domain IU_nuc_hydro PF01156.19 KXL42081.1 - 1.4e-57 195.6 0.0 1.5e-56 192.2 0.0 1.9 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Gal11_ABD1 PF18535.1 KXL42081.1 - 0.2 11.8 0.2 0.37 10.9 0.2 1.4 1 0 0 1 1 1 0 Gal11 activator-binding domain (ABD1) Cupin_8 PF13621.6 KXL42082.1 - 8.4e-25 87.9 0.0 1.1e-24 87.6 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 KXL42082.1 - 0.00032 21.1 0.0 0.0011 19.3 0.0 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 KXL42082.1 - 0.2 11.4 0.0 0.53 10.0 0.0 1.6 2 0 0 2 2 2 0 Cupin domain Vps26 PF03643.15 KXL42083.1 - 3.6e-126 419.8 0.0 4.2e-126 419.6 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KXL42083.1 - 0.0053 16.8 0.3 0.71 9.9 0.0 3.1 2 1 1 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Aldedh PF00171.22 KXL42084.1 - 5.3e-106 354.9 0.0 6.8e-106 354.5 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family 2-oxoacid_dh PF00198.23 KXL42085.1 - 1.3e-74 250.5 0.1 2.2e-74 249.8 0.1 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KXL42085.1 - 1.3e-18 66.6 0.0 1.6e-17 63.1 0.0 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 KXL42085.1 - 6.5e-13 48.8 0.1 1.3e-12 47.8 0.1 1.5 1 0 0 1 1 1 1 e3 binding domain K_trans PF02705.16 KXL42086.1 - 3.4e-184 613.3 21.3 4.1e-184 613.0 21.3 1.0 1 0 0 1 1 1 1 K+ potassium transporter DUF4381 PF14316.6 KXL42086.1 - 1.2 9.3 3.9 0.77 10.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) CBF PF03914.17 KXL42087.1 - 2.5e-54 183.8 0.1 7.3e-54 182.3 0.1 1.9 1 0 0 1 1 1 1 CBF/Mak21 family Cnd1 PF12717.7 KXL42087.1 - 0.0047 17.0 0.9 0.029 14.4 0.0 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 DNA_alkylation PF08713.11 KXL42087.1 - 0.037 13.7 1.6 1.1 9.0 0.5 2.6 3 0 0 3 3 3 0 DNA alkylation repair enzyme DUF5578 PF17741.1 KXL42087.1 - 0.069 12.6 1.6 9.4 5.6 0.2 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5578) zf-C2H2 PF00096.26 KXL42089.1 - 2.2e-06 27.8 8.2 2.2e-05 24.7 1.5 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXL42089.1 - 2.8e-05 24.4 2.4 2.8e-05 24.4 2.4 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KXL42089.1 - 0.00065 19.6 0.2 0.0016 18.4 0.2 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KXL42089.1 - 0.00082 20.0 6.2 0.0077 17.0 0.8 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXL42089.1 - 0.013 15.8 0.7 0.027 14.7 0.7 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Rtf2 PF04641.12 KXL42089.1 - 0.03 13.7 3.4 0.042 13.2 3.4 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger zf-H2C2_5 PF13909.6 KXL42089.1 - 1.5 8.6 6.0 1.2 9.0 0.8 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-met PF12874.7 KXL42089.1 - 4.7 7.7 6.5 0.23 11.9 0.5 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type ESSS PF10183.9 KXL42091.1 - 2.5e-17 63.0 0.0 3.1e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF3720 PF12517.8 KXL42092.1 - 0.27 12.2 2.7 0.39 11.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3720) MOZART1 PF12554.8 KXL42093.1 - 3.8e-26 90.6 0.5 4.6e-26 90.3 0.5 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated TIP49_C PF17856.1 KXL42093.1 - 0.14 12.4 0.9 0.22 11.7 0.9 1.5 1 1 0 1 1 1 0 TIP49 AAA-lid domain Gryzun PF07919.12 KXL42094.1 - 1.5e-118 397.1 0.0 2.4e-118 396.5 0.0 1.3 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 KXL42094.1 - 3.9e-66 223.3 1.6 3.4e-60 203.8 0.4 2.3 2 0 0 2 2 2 2 Foie gras liver health family 1 Ank_5 PF13857.6 KXL42095.1 - 1.8e-44 149.2 10.1 7.2e-11 42.1 0.1 5.4 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXL42095.1 - 1.6e-38 131.1 2.2 2.4e-15 56.9 0.4 3.5 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXL42095.1 - 1.5e-34 117.9 2.7 5.6e-10 39.6 0.1 5.0 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXL42095.1 - 2e-31 104.5 1.3 5.5e-05 23.3 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 KXL42095.1 - 8.4e-27 92.4 5.4 8.9e-05 22.8 0.1 6.2 6 0 0 6 6 6 6 Ankyrin repeat Sulfate_transp PF00916.20 KXL42096.1 - 1.2e-55 188.8 21.9 1.8e-55 188.2 21.9 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 KXL42096.1 - 2.4e-15 56.4 0.0 4.9e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 KXL42096.1 - 1.1e-09 37.9 0.0 2e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 STAS domain CTV_P6 PF06706.11 KXL42096.1 - 2.6 7.8 7.6 0.53 10.0 2.8 2.4 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein DUF805 PF05656.14 KXL42096.1 - 8.6 6.8 8.8 2.2 8.7 0.7 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF805) PH_6 PF15406.6 KXL42097.1 - 8.6e-28 96.9 0.1 8.6e-28 96.9 0.1 3.6 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 KXL42097.1 - 1.2e-05 25.8 0.0 3.1e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 PH domain UBD PF16455.5 KXL42098.1 - 7.3e-29 100.1 0.0 1.2e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 KXL42098.1 - 3.8e-05 23.3 0.0 6.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family FAD_binding_3 PF01494.19 KXL42100.1 - 1.8e-08 34.0 2.2 5.2e-08 32.5 0.4 2.2 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KXL42100.1 - 0.028 13.7 0.1 0.23 10.7 0.1 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXL42100.1 - 0.04 14.1 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXL42100.1 - 0.071 12.2 0.5 0.58 9.2 0.3 2.0 2 0 0 2 2 2 0 FAD binding domain Glutaredoxin PF00462.24 KXL42101.1 - 4.3e-15 55.7 0.0 1.3e-14 54.2 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin Holin_BhlA PF10960.8 KXL42101.1 - 0.033 14.2 3.2 0.09 12.8 3.2 1.7 1 1 0 1 1 1 0 BhlA holin family TraF PF13728.6 KXL42101.1 - 0.069 13.0 2.3 0.73 9.6 2.3 2.1 1 1 0 1 1 1 0 F plasmid transfer operon protein YfhO PF09586.10 KXL42101.1 - 0.17 10.1 0.3 0.22 9.7 0.3 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DSBA PF01323.20 KXL42101.1 - 0.27 11.0 1.8 5.4 6.7 0.1 2.7 2 1 1 3 3 3 0 DSBA-like thioredoxin domain JAB PF01398.21 KXL42102.1 - 2.3e-08 34.0 0.0 9.5e-07 28.8 0.0 2.5 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease GST_N_3 PF13417.6 KXL42103.1 - 4.9e-18 65.3 0.1 8.8e-18 64.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXL42103.1 - 2.5e-15 56.5 0.1 5e-15 55.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXL42103.1 - 3e-09 37.1 0.0 6.1e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXL42103.1 - 7e-05 22.8 0.2 0.00013 21.9 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KXL42103.1 - 0.00089 19.8 0.0 0.0032 18.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Inhibitor_I10 PF12559.8 KXL42103.1 - 0.073 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Serine endopeptidase inhibitors DNA_primase_lrg PF04104.14 KXL42104.1 - 4.9e-79 265.5 0.3 1.1e-78 264.3 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit Ribosomal_L29 PF00831.23 KXL42104.1 - 0.1 12.5 0.2 0.4 10.7 0.2 2.0 1 0 0 1 1 1 0 Ribosomal L29 protein Asp PF00026.23 KXL42105.1 - 1.8e-22 80.2 0.0 2.2e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Esterase PF00756.20 KXL42106.1 - 9.1e-53 179.5 0.0 1.1e-52 179.2 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 KXL42106.1 - 0.0002 20.7 0.0 0.00031 20.1 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase_phd PF10503.9 KXL42106.1 - 0.0015 18.1 0.0 0.015 14.8 0.0 2.0 2 0 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KXL42106.1 - 0.064 12.7 0.1 0.1 12.1 0.1 1.5 1 1 0 1 1 1 0 Prolyl oligopeptidase family Lipase_3 PF01764.25 KXL42106.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) zf-ANAPC11 PF12861.7 KXL42107.1 - 6.4e-20 71.0 1.1 7.5e-20 70.8 1.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KXL42107.1 - 4.2e-06 26.9 1.8 6.3e-06 26.4 1.8 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain IFR3_antag PF14754.6 KXL42107.1 - 0.11 11.7 0.9 0.12 11.6 0.9 1.0 1 0 0 1 1 1 0 Papain-like auto-proteinase HLH PF00010.26 KXL42110.1 - 5.6e-11 42.2 0.0 1.3e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Spt20 PF12090.8 KXL42110.1 - 4.7 6.8 17.3 0.87 9.1 8.7 2.3 2 0 0 2 2 2 0 Spt20 family SAP PF02037.27 KXL42112.1 - 4.9e-10 38.9 0.3 1.4e-09 37.4 0.0 1.9 2 0 0 2 2 2 1 SAP domain Tho1_MOS11_C PF18592.1 KXL42112.1 - 1.7e-06 27.8 0.8 1.7e-06 27.8 0.8 2.4 2 1 0 2 2 2 1 Tho1/MOS11 C-terminal domain TPPII_N PF12583.8 KXL42112.1 - 0.71 10.5 7.6 1.4 9.5 7.6 1.5 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal AMP-binding PF00501.28 KXL42113.1 - 5.2e-58 196.6 0.0 6.2e-58 196.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXL42113.1 - 1.5e-13 51.5 0.0 3.9e-13 50.2 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Nucleoporin_C PF03177.14 KXL42113.1 - 0.15 10.7 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 Non-repetitive/WGA-negative nucleoporin C-terminal ACOX PF01756.19 KXL42114.1 - 3.6e-38 130.9 0.7 7e-38 130.0 0.2 1.7 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KXL42114.1 - 4.2e-27 95.2 0.3 8.2e-27 94.2 0.3 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KXL42114.1 - 2.4e-09 37.3 0.0 5.7e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KXL42114.1 - 0.0017 18.5 0.6 0.017 15.3 0.6 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PAF-AH_p_II PF03403.13 KXL42114.1 - 0.058 11.9 0.0 0.17 10.3 0.0 1.7 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Acyl-CoA_dh_N PF02771.16 KXL42114.1 - 0.098 13.3 0.0 0.33 11.6 0.0 1.9 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain ECH_1 PF00378.20 KXL42115.1 - 3.2e-23 82.3 0.0 3.8e-23 82.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXL42115.1 - 1.1e-09 38.3 0.0 1.3e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Glyco_hydro_43 PF04616.14 KXL42117.1 - 9.2e-31 107.2 5.0 1.1e-30 106.9 5.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 TSGP1 PF07771.11 KXL42117.1 - 0.11 12.6 1.7 0.16 12.1 0.7 1.7 2 0 0 2 2 2 0 Tick salivary peptide group 1 Ish1 PF10281.9 KXL42118.1 - 1.6e-61 204.3 16.6 2.9e-14 53.1 0.1 5.3 5 0 0 5 5 5 5 Putative stress-responsive nuclear envelope protein SAP PF02037.27 KXL42118.1 - 6.9e-08 32.1 0.0 0.061 13.1 0.0 4.6 5 0 0 5 5 5 2 SAP domain HeH PF12949.7 KXL42118.1 - 2.4e-06 27.1 2.0 4.4 7.1 0.0 4.7 5 0 0 5 5 5 3 HeH/LEM domain Slx4 PF09494.10 KXL42118.1 - 8.5e-06 25.6 0.9 0.53 10.3 0.1 3.9 4 1 0 4 4 4 2 Slx4 endonuclease Homeobox_KN PF05920.11 KXL42118.1 - 0.035 14.0 1.0 0.86 9.6 0.2 3.1 3 0 0 3 3 3 0 Homeobox KN domain Apolipoprotein PF01442.18 KXL42118.1 - 0.18 11.7 5.5 1.9 8.3 0.0 3.1 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 KXL42118.1 - 7.1 7.3 12.7 7.2 7.3 4.6 3.7 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) MFS_1 PF07690.16 KXL42120.1 - 1.1e-20 73.9 53.3 1.3e-13 50.7 34.0 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KXL42120.1 - 3.1e-10 39.1 28.2 4.2e-10 38.7 28.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Methyltransf_28 PF02636.17 KXL42121.1 - 2.5e-79 266.6 0.0 3.2e-79 266.3 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Pkinase PF00069.25 KXL42122.1 - 8.4e-60 202.4 0.0 1.6e-59 201.5 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL42122.1 - 3.7e-27 95.2 0.0 5.5e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXL42122.1 - 0.0006 19.2 0.1 0.00094 18.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXL42122.1 - 0.01 15.4 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 KXL42122.1 - 0.012 14.6 0.0 0.02 13.8 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KXL42122.1 - 0.02 14.2 0.0 0.034 13.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KXL42122.1 - 0.17 11.7 0.1 0.17 11.7 0.1 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXL42122.1 - 0.18 10.5 0.6 0.59 8.8 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase RNA_pol_N PF01194.17 KXL42123.1 - 1.1e-28 99.3 0.6 1.4e-28 99.0 0.6 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit DUF1610 PF07754.11 KXL42123.1 - 0.027 14.4 0.0 0.054 13.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) WD40 PF00400.32 KXL42124.1 - 1.8e-06 28.6 1.8 0.0069 17.2 0.0 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat WGG PF10273.9 KXL42125.1 - 3e-31 107.9 0.7 5e-31 107.2 0.7 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 DNA_pol_phi PF04931.13 KXL42125.1 - 7.5 4.5 8.9 11 4.0 8.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi Glyco_hydro_76 PF03663.14 KXL42126.1 - 2e-26 93.4 3.3 1.9e-14 54.0 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 ATG16 PF08614.11 KXL42127.1 - 3.7e-53 180.7 17.0 4.2e-53 180.5 17.0 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Golgin_A5 PF09787.9 KXL42127.1 - 0.00021 20.8 9.7 0.00028 20.5 9.7 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF4201 PF13870.6 KXL42127.1 - 0.00095 18.9 10.3 0.0014 18.4 10.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Baculo_PEP_C PF04513.12 KXL42127.1 - 0.0041 17.2 4.2 0.0057 16.7 4.2 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus MscS_porin PF12795.7 KXL42127.1 - 0.0041 16.7 16.1 0.0041 16.7 16.1 1.4 2 0 0 2 2 1 1 Mechanosensitive ion channel porin domain KELK PF15796.5 KXL42127.1 - 0.01 16.2 4.4 0.01 16.2 4.4 3.5 3 1 1 4 4 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Spc7 PF08317.11 KXL42127.1 - 0.012 14.6 5.0 0.012 14.6 5.0 1.6 1 1 1 2 2 2 0 Spc7 kinetochore protein FliD_C PF07195.12 KXL42127.1 - 0.015 14.8 1.8 0.03 13.8 1.8 1.6 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF812 PF05667.11 KXL42127.1 - 0.017 14.0 10.2 0.02 13.8 10.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) FPP PF05911.11 KXL42127.1 - 0.02 13.1 10.9 0.036 12.3 10.8 1.4 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil DivIC PF04977.15 KXL42127.1 - 0.022 14.5 5.1 0.022 14.5 5.1 2.8 2 1 0 3 3 2 0 Septum formation initiator BST2 PF16716.5 KXL42127.1 - 0.037 14.6 5.0 0.037 14.6 5.0 2.5 3 0 0 3 3 2 0 Bone marrow stromal antigen 2 PKcGMP_CC PF16808.5 KXL42127.1 - 0.051 13.4 1.3 0.051 13.4 1.3 2.2 2 0 0 2 2 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase FAM76 PF16046.5 KXL42127.1 - 0.059 12.7 7.3 0.067 12.5 7.3 1.1 1 0 0 1 1 1 0 FAM76 protein ERM PF00769.19 KXL42127.1 - 0.071 12.9 20.1 0.084 12.7 13.1 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family FlaC_arch PF05377.11 KXL42127.1 - 0.072 13.5 4.2 7.3 7.1 0.5 2.6 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Laminin_II PF06009.12 KXL42127.1 - 0.091 12.8 9.9 0.08 13.0 4.7 2.2 1 1 1 2 2 2 0 Laminin Domain II APG6_N PF17675.1 KXL42127.1 - 0.1 13.1 20.3 0.38 11.3 18.7 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region NPV_P10 PF05531.12 KXL42127.1 - 0.15 12.5 4.5 0.16 12.4 3.1 1.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.9 KXL42127.1 - 0.19 10.8 10.1 0.27 10.3 10.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Phage_GP20 PF06810.11 KXL42127.1 - 0.19 11.5 10.7 0.092 12.5 7.3 2.0 1 1 1 2 2 2 0 Phage minor structural protein GP20 AAA_13 PF13166.6 KXL42127.1 - 0.23 10.1 7.1 0.34 9.5 7.0 1.4 1 1 0 1 1 1 0 AAA domain ZapB PF06005.12 KXL42127.1 - 0.24 11.9 14.1 0.073 13.5 3.7 2.7 3 0 0 3 3 2 0 Cell division protein ZapB DegS PF05384.11 KXL42127.1 - 0.29 10.6 10.0 0.52 9.8 10.0 1.5 1 0 0 1 1 1 0 Sensor protein DegS Ndc1_Nup PF09531.10 KXL42127.1 - 0.31 9.7 3.7 0.37 9.4 3.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup BRE1 PF08647.11 KXL42127.1 - 0.32 11.1 13.3 1.3 9.1 13.2 2.1 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase GAS PF13851.6 KXL42127.1 - 0.36 10.1 13.8 1.3 8.3 13.5 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 KXL42127.1 - 0.37 10.8 7.2 0.35 10.9 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) YabA PF06156.13 KXL42127.1 - 0.42 11.3 11.3 0.3 11.8 3.8 2.3 1 1 1 2 2 2 0 Initiation control protein YabA HAUS-augmin3 PF14932.6 KXL42127.1 - 0.53 9.8 13.5 0.94 9.0 12.7 1.7 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DUF4200 PF13863.6 KXL42127.1 - 0.57 10.6 14.7 6.5 7.2 1.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) SseC PF04888.12 KXL42127.1 - 0.67 9.5 11.2 0.41 10.2 1.5 2.2 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family DUF3450 PF11932.8 KXL42127.1 - 0.69 9.2 16.8 0.094 12.0 10.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 KXL42127.1 - 0.82 9.9 7.3 0.33 11.1 4.6 1.7 2 0 0 2 2 1 0 Fibrinogen alpha/beta chain family FemAB PF02388.16 KXL42127.1 - 0.84 8.4 5.5 0.7 8.7 4.3 1.4 1 1 0 1 1 1 0 FemAB family GLTSCR1 PF15249.6 KXL42127.1 - 0.98 9.9 6.8 9.1 6.8 0.9 2.5 1 1 1 2 2 2 0 Conserved region of unknown function on GLTSCR protein bZIP_1 PF00170.21 KXL42127.1 - 1 9.5 8.2 6.4 7.0 1.6 2.6 2 0 0 2 2 2 0 bZIP transcription factor Prefoldin_2 PF01920.20 KXL42127.1 - 1.2 9.1 13.0 2.3 8.2 5.2 3.1 1 1 2 3 3 3 0 Prefoldin subunit DUF4407 PF14362.6 KXL42127.1 - 1.3 8.3 16.7 0.54 9.6 14.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Sec34 PF04136.15 KXL42127.1 - 1.3 8.9 7.6 0.52 10.2 2.3 2.1 1 1 1 2 2 2 0 Sec34-like family DASH_Hsk3 PF08227.11 KXL42127.1 - 1.7 9.1 10.7 1.5 9.2 5.0 3.2 2 1 1 3 3 3 0 DASH complex subunit Hsk3 like CENP-H PF05837.12 KXL42127.1 - 1.8 9.0 19.3 0.56 10.6 9.1 2.4 2 1 1 3 3 2 0 Centromere protein H (CENP-H) Jnk-SapK_ap_N PF09744.9 KXL42127.1 - 1.9 8.7 16.7 0.21 11.8 6.6 2.3 2 1 1 3 3 2 0 JNK_SAPK-associated protein-1 ADIP PF11559.8 KXL42127.1 - 2.1 8.4 15.8 0.24 11.5 9.2 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF948 PF06103.11 KXL42127.1 - 2.5 8.4 5.8 2 8.7 3.8 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) TPR_MLP1_2 PF07926.12 KXL42127.1 - 3 7.9 22.6 0.037 14.1 7.9 2.7 2 1 1 3 3 2 0 TPR/MLP1/MLP2-like protein COG2 PF06148.11 KXL42127.1 - 3.1 7.9 7.7 20 5.2 6.1 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TMPIT PF07851.13 KXL42127.1 - 3.2 6.9 5.3 4.3 6.5 5.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF724 PF05266.14 KXL42127.1 - 3.2 7.5 10.0 3.5 7.4 8.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) UPF0242 PF06785.11 KXL42127.1 - 3.3 7.8 13.3 16 5.5 13.3 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Cnn_1N PF07989.11 KXL42127.1 - 3.3 7.9 12.9 11 6.2 5.7 3.3 3 1 0 3 3 2 0 Centrosomin N-terminal motif 1 CCDC-167 PF15188.6 KXL42127.1 - 4 7.9 9.8 20 5.6 9.6 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 NYD-SP28_assoc PF14775.6 KXL42127.1 - 4.3 7.5 10.9 34 4.6 0.0 4.0 3 1 1 4 4 4 0 Sperm tail C-terminal domain Seryl_tRNA_N PF02403.22 KXL42127.1 - 4.5 7.5 12.8 1.2 9.4 4.7 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain YlqD PF11068.8 KXL42127.1 - 5.2 7.4 15.0 5.4 7.4 13.0 1.9 2 1 0 2 2 1 0 YlqD protein FlxA PF14282.6 KXL42127.1 - 6.6 6.8 15.1 3.6 7.6 5.8 2.6 1 1 1 2 2 2 0 FlxA-like protein GrpE PF01025.19 KXL42127.1 - 7.6 6.2 12.3 1.1 8.9 3.5 2.2 1 1 1 2 2 2 0 GrpE TMF_DNA_bd PF12329.8 KXL42127.1 - 7.7 6.6 14.1 1.8 8.6 5.2 2.9 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding CorA PF01544.18 KXL42128.1 - 1e-25 90.6 13.2 3.2e-20 72.6 2.1 3.1 2 1 1 3 3 3 3 CorA-like Mg2+ transporter protein Brr6_like_C_C PF10104.9 KXL42128.1 - 0.064 13.0 0.2 0.064 13.0 0.2 1.9 2 0 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain zf-MYND PF01753.18 KXL42129.1 - 3.1e-08 33.6 18.5 8.6e-08 32.1 18.5 1.8 1 0 0 1 1 1 1 MYND finger PhoLip_ATPase_C PF16212.5 KXL42130.1 - 8.7e-67 225.5 23.6 8.7e-67 225.5 23.6 2.4 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KXL42130.1 - 2.8e-24 84.6 0.5 7e-22 76.9 0.0 2.7 2 0 0 2 2 2 2 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KXL42130.1 - 3.9e-13 50.2 0.6 6.1e-05 23.4 0.0 3.6 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXL42130.1 - 9.7e-12 44.8 0.0 9.8e-11 41.6 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KXL42130.1 - 2.3e-08 33.8 0.1 1.2e-07 31.4 0.1 2.1 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KXL42130.1 - 0.00058 19.7 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Transglut_core PF01841.19 KXL42131.1 - 1.6e-11 44.7 0.0 3.3e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Gln_amidase PF15644.6 KXL42131.1 - 0.02 15.9 0.0 0.056 14.5 0.0 1.8 1 0 0 1 1 1 0 Papain fold toxin 1, glutamine deamidase DUF553 PF04473.12 KXL42131.1 - 0.082 12.4 0.0 2 8.0 0.0 2.4 1 1 0 1 1 1 0 Transglutaminase-like domain LSM PF01423.22 KXL42132.1 - 7.1e-19 67.3 0.1 8.8e-19 67.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain ATP13 PF12921.7 KXL42133.1 - 9.3e-25 86.7 0.0 2.6e-24 85.3 0.0 1.8 1 0 0 1 1 1 1 Mitochondrial ATPase expression PPR_2 PF13041.6 KXL42133.1 - 0.0085 16.3 0.0 0.085 13.1 0.0 2.7 3 0 0 3 3 3 1 PPR repeat family Phage_clamp_A PF16790.5 KXL42133.1 - 0.094 13.2 0.0 0.33 11.4 0.0 1.8 2 0 0 2 2 2 0 Bacteriophage clamp loader A subunit Inositol_P PF00459.25 KXL42136.1 - 4.8e-68 229.6 0.0 5.2e-68 229.5 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family VPS9 PF02204.18 KXL42137.1 - 3.8e-21 75.3 0.0 7.8e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Lipase_3 PF01764.25 KXL42139.1 - 4.5e-05 23.4 0.0 0.00012 21.9 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) Hydrolase_4 PF12146.8 KXL42139.1 - 0.02 14.2 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KXL42139.1 - 0.021 14.6 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 KXL42139.1 - 0.066 12.9 0.1 0.16 11.7 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein Ala_racemase_N PF01168.20 KXL42140.1 - 1.1e-21 77.6 0.1 1.3e-21 77.3 0.1 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain CUE PF02845.16 KXL42141.1 - 4.2e-09 35.9 0.0 7.9e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 CUE domain ARL6IP6 PF15062.6 KXL42142.1 - 0.024 14.8 1.3 0.038 14.1 0.1 1.8 1 1 0 2 2 2 0 Haemopoietic lineage transmembrane helix zf-C2H2_12 PF18658.1 KXL42142.1 - 0.39 10.3 2.5 0.45 10.1 0.1 2.2 1 1 1 2 2 2 0 Zinc-finger C2H2-type Aldo_ket_red PF00248.21 KXL42143.1 - 6.8e-51 173.2 0.0 1.9e-50 171.7 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family Hydrolase_6 PF13344.6 KXL42144.1 - 1.3e-21 76.6 0.0 2.5e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXL42144.1 - 4.9e-19 68.2 0.0 1.5e-18 66.6 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KXL42144.1 - 0.086 13.1 0.1 0.89 9.8 0.1 2.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase F-box-like PF12937.7 KXL42145.1 - 3.7e-05 23.5 0.1 0.0001 22.1 0.1 1.8 1 1 0 1 1 1 1 F-box-like LRR_8 PF13855.6 KXL42145.1 - 0.012 15.4 1.4 0.012 15.4 1.4 2.3 2 0 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 KXL42145.1 - 0.068 13.6 4.7 0.46 11.0 1.0 3.1 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) AlkA_N PF06029.11 KXL42145.1 - 0.077 13.3 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 AlkA N-terminal domain Vps35 PF03635.17 KXL42146.1 - 5.1e-304 1010.5 0.0 5.9e-304 1010.3 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 PAP1 PF08601.10 KXL42146.1 - 0.013 15.2 0.3 0.021 14.5 0.3 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Nexin_C PF08628.12 KXL42146.1 - 0.073 13.6 0.0 4.5 7.9 0.0 3.7 4 1 1 5 5 5 0 Sorting nexin C terminal Glycos_transf_2 PF00535.26 KXL42147.1 - 3.4e-35 121.4 0.0 4e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KXL42147.1 - 4.7e-10 39.7 0.0 7.1e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KXL42147.1 - 2.1e-05 24.1 0.0 3.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 KXL42147.1 - 0.0039 16.7 0.0 0.0052 16.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Dus PF01207.17 KXL42148.1 - 1.8e-59 201.4 0.0 2.1e-59 201.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 KXL42148.1 - 0.00072 19.1 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein TMP-TENI PF02581.17 KXL42148.1 - 0.18 11.1 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Thiamine monophosphate synthase F-box-like PF12937.7 KXL42149.1 - 2.1 8.3 4.6 0.6 10.1 0.2 2.3 2 0 0 2 2 2 0 F-box-like TP6A_N PF04406.14 KXL42150.1 - 8.5e-23 80.1 0.0 1.9e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 Type IIB DNA topoisomerase CAF1A PF12253.8 KXL42151.1 - 6.8e-21 74.2 3.5 6.8e-21 74.2 3.5 2.8 3 0 0 3 3 3 1 Chromatin assembly factor 1 subunit A CENP-N PF05238.13 KXL42151.1 - 4.4 6.5 8.8 7.8 5.7 8.8 1.3 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Borrelia_P83 PF05262.11 KXL42151.1 - 6.2 5.2 15.2 11 4.3 15.2 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein ERCC3_RAD25_C PF16203.5 KXL42152.1 - 3.6e-120 399.7 0.1 8.5e-120 398.5 0.1 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KXL42152.1 - 1.4e-34 119.0 0.0 2.9e-34 117.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL42152.1 - 2.6e-16 60.1 0.2 6.6e-16 58.8 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXL42152.1 - 3.9e-10 40.1 0.1 1.5e-09 38.2 0.1 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KXL42152.1 - 2.8e-07 29.6 0.1 4e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 KXL42152.1 - 0.00017 21.4 0.0 0.0003 20.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Elf4 PF07011.11 KXL42152.1 - 0.068 13.1 0.2 2.3 8.2 0.0 2.4 2 0 0 2 2 2 0 Early Flowering 4 domain DUF4748 PF15932.5 KXL42153.1 - 1.3e-17 63.2 0.7 2.1e-17 62.6 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) MPP6 PF10175.9 KXL42154.1 - 1.4e-06 28.8 12.7 0.0016 18.9 1.8 3.0 2 1 1 3 3 3 2 M-phase phosphoprotein 6 zf-CCHC PF00098.23 KXL42154.1 - 1.6e-05 24.7 5.2 2.5e-05 24.2 5.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 KXL42154.1 - 0.058 13.2 5.7 0.098 12.5 5.7 1.4 1 0 0 1 1 1 0 Zinc knuckle RR_TM4-6 PF06459.12 KXL42154.1 - 6.6 6.5 7.3 1.6 8.5 3.2 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Acyl_transf_3 PF01757.22 KXL42155.1 - 2.9e-26 92.3 33.3 4.5e-26 91.7 33.2 1.4 1 1 0 1 1 1 1 Acyltransferase family UQ_con PF00179.26 KXL42156.1 - 3.9e-51 172.4 0.0 4.4e-51 172.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Scramblase PF03803.15 KXL42157.1 - 2e-53 180.9 1.3 4.6e-29 101.3 0.1 3.0 2 1 0 2 2 2 2 Scramblase WD40 PF00400.32 KXL42158.1 - 1.4e-08 35.3 0.4 0.0043 17.9 0.1 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL42158.1 - 0.0019 18.4 0.0 0.003 17.8 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain RPN6_N PF18055.1 KXL42159.1 - 2.9e-42 143.7 0.4 7.2e-42 142.4 0.1 1.9 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 KXL42159.1 - 6.7e-20 71.6 1.2 1.4e-19 70.5 0.3 2.0 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 KXL42159.1 - 8.5e-12 44.6 0.3 2e-11 43.4 0.3 1.7 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_7 PF13176.6 KXL42159.1 - 0.00035 20.4 4.1 0.35 11.0 0.3 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KXL42159.1 - 0.001 18.5 6.2 0.0016 17.9 1.3 2.9 1 1 2 3 3 3 1 MalT-like TPR region NepR PF18557.1 KXL42159.1 - 0.0041 16.7 0.1 0.016 14.9 0.0 2.1 2 0 0 2 2 2 1 Anti-sigma factor NepR DDRGK PF09756.9 KXL42159.1 - 0.025 14.2 0.1 0.025 14.2 0.1 1.7 2 0 0 2 2 2 0 DDRGK domain TPR_12 PF13424.6 KXL42159.1 - 0.042 14.1 13.0 1.7 9.0 0.4 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.9 KXL42159.1 - 0.3 10.8 7.9 0.069 12.9 0.8 2.7 1 1 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_1 PF00515.28 KXL42159.1 - 0.34 10.8 3.7 2.4 8.1 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXL42159.1 - 0.83 9.9 5.5 23 5.4 0.6 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Glyco_hydro_cc PF11790.8 KXL42161.1 - 2.1e-73 246.8 4.1 2.4e-73 246.6 4.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core MFS_1 PF07690.16 KXL42162.1 - 1.6e-17 63.5 38.2 8.6e-11 41.4 21.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXL42162.1 - 0.003 16.5 9.7 0.056 12.3 0.3 2.3 2 0 0 2 2 2 2 MFS_1 like family DUF4407 PF14362.6 KXL42162.1 - 0.46 9.8 1.3 0.89 8.9 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MFS_1 PF07690.16 KXL42163.1 - 4.6e-21 75.1 51.2 4.6e-21 75.1 51.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DNA_methylase PF00145.17 KXL42164.1 - 5.4e-20 72.0 0.1 3.6e-19 69.3 0.0 2.3 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase SNF2_N PF00176.23 KXL42164.1 - 2.9e-15 55.8 0.0 1.8e-14 53.2 0.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXL42164.1 - 3.9e-09 36.8 0.1 9.1e-09 35.6 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL42164.1 - 0.0034 17.4 2.0 0.03 14.3 0.0 2.7 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit zf-RING_4 PF14570.6 KXL42164.1 - 0.0051 16.6 3.3 0.018 14.8 3.3 1.9 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_5 PF17121.5 KXL42164.1 - 0.012 15.5 4.4 0.029 14.2 4.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXL42164.1 - 0.015 15.1 12.3 0.025 14.4 3.1 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF3520 PF12034.8 KXL42164.1 - 0.079 13.1 0.1 4.1 7.5 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3520) Prok-RING_4 PF14447.6 KXL42164.1 - 0.34 10.8 4.6 1.3 8.9 4.6 2.0 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KXL42164.1 - 1.6 8.8 12.5 0.074 13.1 3.3 2.7 2 0 0 2 2 2 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KXL42164.1 - 3.5 7.3 16.5 4.9 6.9 2.4 3.0 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 KXL42164.1 - 4.1 7.8 16.3 0.58 10.5 4.8 2.8 2 0 0 2 2 2 0 Ring finger domain FYVE_2 PF02318.16 KXL42164.1 - 5.3 7.3 10.5 3.6 7.8 0.5 2.7 2 0 0 2 2 2 0 FYVE-type zinc finger zf-C3HC4 PF00097.25 KXL42164.1 - 7.1 6.6 15.0 0.19 11.6 6.5 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Sof1 PF04158.14 KXL42165.1 - 2.8e-32 110.8 19.1 4.2e-32 110.3 19.1 1.3 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 KXL42165.1 - 1.6e-17 63.5 0.4 8.5e-06 26.4 0.2 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL42165.1 - 2e-05 24.8 0.0 0.0035 17.6 0.0 3.2 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXL42165.1 - 0.044 12.7 0.0 0.77 8.7 0.0 2.2 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Glyco_hydro_76 PF03663.14 KXL42167.1 - 4.2e-24 85.8 3.9 2.7e-18 66.7 0.3 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KXL42167.1 - 0.011 14.8 0.2 0.02 14.0 0.2 1.4 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 Sugar_tr PF00083.24 KXL42168.1 - 4.1e-72 243.5 24.3 5e-72 243.2 24.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL42168.1 - 1.6e-14 53.6 59.7 4.8e-14 52.1 35.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF21 PF01595.20 KXL42169.1 - 3.4e-33 114.8 0.0 5.4e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KXL42169.1 - 7.9e-07 29.4 0.4 0.031 14.7 0.0 2.6 2 0 0 2 2 2 2 CBS domain AAA_22 PF13401.6 KXL42170.1 - 2.5e-05 24.6 0.2 0.012 15.9 0.0 2.5 2 1 0 2 2 2 2 AAA domain TrwB_AAD_bind PF10412.9 KXL42170.1 - 0.0015 17.5 0.1 0.16 10.9 0.0 2.2 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.6 KXL42170.1 - 0.0034 17.8 0.0 0.033 14.6 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KXL42170.1 - 0.0045 16.3 0.0 0.01 15.2 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin FtsK_SpoIIIE PF01580.18 KXL42170.1 - 0.0058 16.0 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF87 PF01935.17 KXL42170.1 - 0.0074 16.4 0.0 0.56 10.3 0.0 2.2 2 0 0 2 2 2 1 Helicase HerA, central domain ABC_tran PF00005.27 KXL42170.1 - 0.014 15.9 0.3 0.049 14.2 0.2 2.0 2 1 0 2 2 2 0 ABC transporter ATPase_2 PF01637.18 KXL42170.1 - 0.024 14.6 0.0 0.72 9.7 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_15 PF13175.6 KXL42170.1 - 0.04 13.6 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain HutP PF09021.11 KXL42170.1 - 0.14 12.5 0.3 0.3 11.4 0.3 1.5 1 0 0 1 1 1 0 HutP Peptidase_M20 PF01546.28 KXL42171.1 - 8.7e-23 81.1 0.0 6.5e-21 75.0 0.0 3.0 3 0 0 3 3 3 1 Peptidase family M20/M25/M40 WD40 PF00400.32 KXL42171.1 - 7.2e-10 39.3 0.1 0.19 12.6 0.0 5.6 5 0 0 5 5 5 2 WD domain, G-beta repeat M20_dimer PF07687.14 KXL42171.1 - 4.9e-06 26.4 0.0 1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Spermine_synth PF01564.17 KXL42171.1 - 0.14 11.6 0.0 3.2 7.1 0.1 2.4 2 0 0 2 2 2 0 Spermine/spermidine synthase domain PikAIV_N PF18605.1 KXL42171.1 - 5.2 6.7 6.7 1.6 8.4 0.1 3.0 3 0 0 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain SelR PF01641.18 KXL42172.1 - 6.2e-52 174.8 0.2 8.1e-52 174.4 0.2 1.1 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 KXL42172.1 - 0.0023 17.6 0.1 0.36 10.6 0.0 2.3 2 0 0 2 2 2 1 Predicted integral membrane zinc-ribbon metal-binding protein GFA PF04828.14 KXL42172.1 - 0.011 16.0 1.1 0.39 11.1 0.1 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Tnp_zf-ribbon_2 PF13842.6 KXL42172.1 - 0.07 13.9 0.5 14 6.6 0.1 2.3 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon MCM_OB PF17207.3 KXL42172.1 - 0.081 12.8 0.3 0.16 11.8 0.0 1.6 2 0 0 2 2 2 0 MCM OB domain Yippee-Mis18 PF03226.14 KXL42172.1 - 0.092 13.0 0.4 0.35 11.1 0.4 2.0 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TF_Zn_Ribbon PF08271.12 KXL42172.1 - 0.39 10.3 4.5 0.52 9.9 0.2 2.5 3 0 0 3 3 3 0 TFIIB zinc-binding zf-Mss51 PF13824.6 KXL42172.1 - 0.41 10.8 2.6 7 6.8 0.3 3.3 3 1 1 4 4 4 0 Zinc-finger of mitochondrial splicing suppressor 51 DZR PF12773.7 KXL42172.1 - 0.71 10.0 5.0 8.5 6.5 0.9 2.3 1 1 1 2 2 2 0 Double zinc ribbon DUF3060 PF11259.8 KXL42173.1 - 1.5 8.6 4.8 9.4 6.0 0.9 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3060) YjhX_toxin PF09857.9 KXL42174.1 - 0.08 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative toxin of bacterial toxin-antitoxin pair DUF3720 PF12517.8 KXL42174.1 - 0.79 10.7 3.6 1.3 10.0 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3720) DUF1771 PF08590.10 KXL42175.1 - 3.3e-17 62.6 18.7 3.3e-17 62.6 18.7 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 KXL42175.1 - 7e-11 42.3 0.1 1.5e-10 41.3 0.1 1.5 1 0 0 1 1 1 1 Smr domain DUF357 PF04010.13 KXL42175.1 - 0.03 14.4 2.8 3.4 7.8 0.1 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF357) DUF4407 PF14362.6 KXL42175.1 - 5.7 6.2 6.4 7.3 5.8 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3847 PF12958.7 KXL42175.1 - 8 6.7 8.2 35 4.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) Aminotran_5 PF00266.19 KXL42176.1 - 9.8e-96 320.9 0.0 1.1e-95 320.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KXL42176.1 - 1.1e-06 28.2 0.0 1.4e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KXL42176.1 - 5.7e-06 25.9 0.1 0.00015 21.2 0.0 2.2 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 KXL42176.1 - 0.0014 17.4 0.0 0.002 16.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain zf-C4 PF00105.18 KXL42176.1 - 0.0058 17.1 0.8 0.0058 17.1 0.8 1.7 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Cys_Met_Meta_PP PF01053.20 KXL42176.1 - 0.021 13.3 0.0 0.031 12.8 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme UcrQ PF02939.16 KXL42177.1 - 1.7e-33 114.4 0.2 2e-33 114.2 0.2 1.1 1 0 0 1 1 1 1 UcrQ family Band_7 PF01145.25 KXL42178.1 - 1.3e-24 87.1 4.6 2.2e-24 86.4 4.6 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 KXL42178.1 - 0.00016 20.9 2.5 0.00016 20.9 2.5 1.4 2 0 0 2 2 2 1 SigmaW regulon antibacterial GatB_Yqey PF02637.18 KXL42178.1 - 0.046 13.6 0.9 0.097 12.5 0.9 1.5 1 1 0 1 1 1 0 GatB domain Actin PF00022.19 KXL42179.1 - 1.5e-112 376.2 0.0 9.6e-112 373.5 0.0 1.8 1 1 0 1 1 1 1 Actin Actin_micro PF17003.5 KXL42179.1 - 0.012 14.8 0.3 0.23 10.6 0.2 2.2 2 0 0 2 2 2 0 Putative actin-like family MreB_Mbl PF06723.13 KXL42179.1 - 0.026 13.4 0.0 0.087 11.6 0.0 1.8 1 1 0 1 1 1 0 MreB/Mbl protein Sugar_tr PF00083.24 KXL42181.1 - 4.9e-81 272.9 22.8 5.8e-81 272.6 22.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL42181.1 - 2.5e-26 92.5 26.0 4.8e-20 71.8 10.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXL42181.1 - 1.2e-05 24.0 1.2 1.2e-05 24.0 1.2 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1304 PF06993.12 KXL42181.1 - 0.49 10.4 9.7 0.89 9.6 1.8 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1304) HET PF06985.11 KXL42182.1 - 7e-31 107.6 0.0 1.4e-30 106.6 0.0 1.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_M28 PF04389.17 KXL42184.1 - 4.1e-34 118.0 0.0 6.1e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Cyclin_C_2 PF16899.5 KXL42185.1 - 0.0069 16.7 0.3 0.02 15.2 0.1 1.9 2 1 0 2 2 2 1 Cyclin C-terminal domain Mito_carr PF00153.27 KXL42186.1 - 4.3e-67 222.1 5.7 2.3e-24 85.1 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 KXL42186.1 - 2.9e-22 76.5 5.4 2.3e-06 26.7 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KXL42186.1 - 2.8e-21 75.7 6.0 3e-10 40.4 1.2 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KXL42186.1 - 1e-17 62.4 7.1 0.00012 21.7 1.4 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KXL42186.1 - 3.4e-15 54.7 6.5 4.6e-06 25.9 0.5 3.4 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KXL42186.1 - 9.5e-11 41.4 3.9 2.2e-05 24.2 0.1 3.9 3 2 2 5 5 5 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KXL42186.1 - 2e-09 37.7 0.2 0.0024 18.2 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KXL42186.1 - 0.0037 17.2 2.6 0.27 11.2 0.1 2.7 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 KXL42186.1 - 0.019 14.8 1.6 1.8 8.5 0.0 3.1 3 0 0 3 3 3 0 EF hand Limkain-b1 PF11608.8 KXL42186.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 Pro_isomerase PF00160.21 KXL42187.1 - 3.9e-50 170.2 0.0 4.5e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-B_box PF00643.24 KXL42187.1 - 0.1 12.7 0.4 0.15 12.2 0.4 1.2 1 0 0 1 1 1 0 B-box zinc finger Radical_SAM PF04055.21 KXL42188.1 - 2.1e-23 83.5 0.1 4.9e-23 82.3 0.1 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.12 KXL42188.1 - 6e-19 68.2 0.0 1.2e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.25 KXL42188.1 - 1.8e-06 28.2 1.0 1.8e-06 28.2 1.0 2.9 3 1 0 3 3 3 1 Flavodoxin Utp14 PF04615.13 KXL42188.1 - 0.00048 18.9 0.6 0.00067 18.4 0.6 1.1 1 0 0 1 1 1 1 Utp14 protein Fungal_trans PF04082.18 KXL42189.1 - 4.2e-11 42.4 0.0 8.3e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL42189.1 - 7.1e-07 29.2 13.5 7.1e-07 29.2 13.5 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KXL42190.1 - 4.1e-90 302.8 20.6 4.7e-90 302.6 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL42190.1 - 9.4e-22 77.4 38.4 7.8e-15 54.6 14.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5597 PF18120.1 KXL42191.1 - 2.6e-28 98.8 0.0 4e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5597) Glyco_hydro_42 PF02449.15 KXL42191.1 - 1.2e-08 34.7 0.0 2.1e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_35 PF01301.19 KXL42191.1 - 4e-06 26.7 0.0 0.0037 17.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 35 SUZ PF12752.7 KXL42193.1 - 0.0077 17.0 1.9 0.019 15.7 1.9 1.6 1 0 0 1 1 1 1 SUZ domain Chorismate_synt PF01264.21 KXL42194.1 - 6e-139 462.3 0.0 6.9e-139 462.1 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Porin_3 PF01459.22 KXL42195.1 - 2.5e-53 181.3 5.9 3e-53 181.0 5.9 1.0 1 0 0 1 1 1 1 Eukaryotic porin P_proprotein PF01483.20 KXL42195.1 - 0.043 13.8 0.0 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 Proprotein convertase P-domain Asn_synthase PF00733.21 KXL42196.1 - 1.1e-92 311.4 0.0 1.5e-54 186.0 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KXL42196.1 - 3.8e-38 130.2 0.0 6e-38 129.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KXL42196.1 - 3.5e-29 101.7 0.0 5.6e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KXL42196.1 - 0.00028 20.4 0.0 0.0005 19.6 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 KXL42196.1 - 0.026 13.6 0.0 0.054 12.6 0.0 1.4 1 0 0 1 1 1 0 NAD synthase CRAL_TRIO_2 PF13716.6 KXL42197.1 - 4.9e-29 101.3 0.0 8e-29 100.6 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 KXL42197.1 - 3.2e-20 72.5 0.0 5.9e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO PF00650.20 KXL42197.1 - 0.0012 18.6 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain Ank_2 PF12796.7 KXL42198.1 - 3.2e-26 91.7 1.8 1.4e-11 44.8 0.1 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXL42198.1 - 2.1e-21 76.0 6.4 1.7e-10 41.2 0.2 4.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) SPX PF03105.19 KXL42198.1 - 2.1e-20 74.0 16.7 1e-07 32.3 0.8 3.2 1 1 2 3 3 3 3 SPX domain GDPD PF03009.17 KXL42198.1 - 1.6e-12 47.7 0.0 7.4e-12 45.5 0.0 2.0 2 1 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_3 PF13606.6 KXL42198.1 - 1.7e-10 40.2 6.9 0.096 13.3 0.1 6.7 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 KXL42198.1 - 1.4e-07 31.6 6.1 0.15 12.4 0.0 5.3 1 1 4 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 KXL42198.1 - 8.9e-07 29.1 14.7 0.0035 17.7 0.1 6.7 8 0 0 8 8 8 1 Ankyrin repeat DUF2914 PF11141.8 KXL42198.1 - 0.2 11.4 0.0 0.53 10.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) AF-4 PF05110.13 KXL42198.1 - 0.94 7.5 3.7 1.3 7.0 3.7 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Methyltransf_16 PF10294.9 KXL42199.1 - 1e-41 142.6 0.0 1.4e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KXL42199.1 - 0.0018 17.9 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 KXL42199.1 - 0.047 13.4 0.0 0.09 12.5 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein DUF43 PF01861.16 KXL42199.1 - 0.064 12.5 0.0 0.08 12.2 0.0 1.1 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Methyltransf_25 PF13649.6 KXL42199.1 - 0.13 12.9 0.0 0.28 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KXL42199.1 - 0.2 11.0 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Coa1 PF08695.10 KXL42201.1 - 8.8e-42 141.5 0.2 1.1e-41 141.3 0.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF2431 PF10354.9 KXL42202.1 - 1.7e-66 223.6 0.0 2.1e-66 223.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Oxidored_q6 PF01058.22 KXL42203.1 - 1.2e-21 76.9 0.1 1.6e-21 76.5 0.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Sedlin_N PF04628.13 KXL42204.1 - 1.7e-12 47.6 0.0 2.7e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Glyco_hydro_92 PF07971.12 KXL42205.1 - 7.1e-40 137.3 0.0 8.7e-19 67.8 0.1 4.1 1 1 3 4 4 4 4 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KXL42205.1 - 9.4e-37 127.2 0.1 7.4e-36 124.2 0.0 2.2 1 1 2 3 3 3 1 Glycosyl hydrolase family 92 N-terminal domain Glyco_hydro_28 PF00295.17 KXL42206.1 - 2.6e-35 122.1 1.6 1.5e-34 119.6 1.6 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_12 PF01670.16 KXL42207.1 - 1.7e-36 126.2 12.9 3.5e-36 125.2 12.9 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 DUF1849 PF08904.11 KXL42209.1 - 0.05 13.1 0.1 0.064 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1849) Rhabdo_matrix PF03397.14 KXL42209.1 - 0.07 12.9 0.0 0.096 12.4 0.0 1.3 1 0 0 1 1 1 0 Rhabdovirus matrix protein ATG16 PF08614.11 KXL42210.1 - 2.5e-06 27.9 67.8 0.02 15.1 26.2 3.2 1 1 2 3 3 3 3 Autophagy protein 16 (ATG16) Fez1 PF06818.15 KXL42210.1 - 0.00012 22.6 60.1 0.0052 17.3 23.6 3.1 1 1 2 3 3 3 3 Fez1 Golgin_A5 PF09787.9 KXL42210.1 - 0.0006 19.4 14.5 0.0006 19.4 14.5 3.0 1 1 2 3 3 3 1 Golgin subfamily A member 5 Spc7 PF08317.11 KXL42210.1 - 0.00079 18.4 19.9 0.00079 18.4 19.9 3.1 1 1 2 3 3 3 2 Spc7 kinetochore protein GAS PF13851.6 KXL42210.1 - 0.0037 16.7 61.7 0.09 12.1 13.2 3.7 1 1 3 4 4 4 3 Growth-arrest specific micro-tubule binding CEP63 PF17045.5 KXL42210.1 - 0.0095 15.9 53.1 0.11 12.4 14.6 2.5 1 1 1 2 2 2 1 Centrosomal protein of 63 kDa DUF1664 PF07889.12 KXL42210.1 - 0.014 15.4 2.4 0.014 15.4 2.4 4.5 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) HMMR_N PF15905.5 KXL42210.1 - 0.032 13.7 60.2 0.19 11.1 28.9 3.0 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal MAD PF05557.13 KXL42210.1 - 0.042 12.2 61.7 0.27 9.6 31.7 2.2 1 1 1 2 2 2 0 Mitotic checkpoint protein EzrA PF06160.12 KXL42210.1 - 0.051 11.8 46.4 0.044 12.0 16.3 2.4 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA CENP-F_leu_zip PF10473.9 KXL42210.1 - 0.078 13.0 62.6 2.2 8.3 25.5 3.8 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 KXL42210.1 - 0.11 12.1 59.1 0.54 9.8 17.2 3.2 1 1 2 3 3 3 0 Intermediate filament protein AAA_13 PF13166.6 KXL42210.1 - 0.17 10.5 51.5 2.6 6.6 14.3 3.0 1 1 2 3 3 3 0 AAA domain Cast PF10174.9 KXL42210.1 - 0.32 9.2 54.1 0.27 9.4 42.1 2.0 1 1 1 2 2 2 0 RIM-binding protein of the cytomatrix active zone ADIP PF11559.8 KXL42210.1 - 0.41 10.7 60.2 3.1 7.9 12.6 4.1 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding FPP PF05911.11 KXL42210.1 - 0.77 7.9 51.8 1.8 6.7 32.4 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DUF4407 PF14362.6 KXL42210.1 - 0.96 8.7 60.4 0.3 10.4 28.8 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) BicD PF09730.9 KXL42210.1 - 1.1 7.6 52.8 0.011 14.2 30.1 2.5 1 1 1 2 2 2 0 Microtubule-associated protein Bicaudal-D OmpH PF03938.14 KXL42210.1 - 1.6 9.0 74.0 0.11 12.9 25.3 3.9 1 1 2 3 3 2 0 Outer membrane protein (OmpH-like) DUF3584 PF12128.8 KXL42210.1 - 3.7 4.9 63.0 2 5.8 41.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) FUSC PF04632.12 KXL42210.1 - 3.8 5.9 42.8 10 4.5 15.9 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family Lectin_N PF03954.14 KXL42210.1 - 6.1 6.6 33.9 4.8 6.9 4.7 4.5 1 1 2 4 4 4 0 Hepatic lectin, N-terminal domain Laminin_II PF06009.12 KXL42210.1 - 6.9 6.7 46.2 0.79 9.7 10.4 3.7 1 1 3 4 4 4 0 Laminin Domain II DUF4201 PF13870.6 KXL42210.1 - 7.1 6.3 49.0 1.2 8.8 10.1 3.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) DUF3450 PF11932.8 KXL42210.1 - 7.4 5.8 64.6 0.21 10.9 15.6 4.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 KXL42210.1 - 7.8 7.0 76.7 2.2 8.8 14.5 4.4 1 1 3 4 4 4 0 Apg6 coiled-coil region HAP1_N PF04849.13 KXL42210.1 - 9.6 5.3 54.3 0.038 13.2 15.1 3.1 1 1 2 3 3 3 0 HAP1 N-terminal conserved region MscS_porin PF12795.7 KXL42210.1 - 9.7 5.7 66.7 6 6.3 7.6 3.8 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain RTA1 PF04479.13 KXL42211.1 - 8.1e-67 224.8 11.4 1.1e-66 224.3 11.4 1.2 1 0 0 1 1 1 1 RTA1 like protein COA2 PF17051.5 KXL42211.1 - 0.04 14.0 0.0 5.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Cytochrome C oxidase assembly factor 2 DUF4059 PF13268.6 KXL42211.1 - 0.56 10.7 7.0 0.065 13.7 1.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) Keratin_assoc PF09775.9 KXL42211.1 - 3.9 7.2 8.5 5.5 6.7 2.1 2.6 2 1 0 2 2 2 0 Keratinocyte-associated protein 2 Methyltransf_23 PF13489.6 KXL42212.1 - 1.7e-20 73.5 0.0 2.5e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL42212.1 - 7.7e-14 52.2 0.0 1.9e-13 50.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL42212.1 - 9.5e-12 45.4 0.0 1.6e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL42212.1 - 1.7e-10 41.5 0.0 1.6e-09 38.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL42212.1 - 4e-10 39.7 0.0 0.00085 19.1 0.0 2.5 3 0 0 3 3 3 2 Methyltransferase domain PrmA PF06325.13 KXL42212.1 - 0.0008 18.9 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KXL42212.1 - 0.0012 18.4 0.2 0.0058 16.1 0.0 2.1 3 0 0 3 3 3 1 Putative methyltransferase Methyltransf_16 PF10294.9 KXL42212.1 - 0.005 16.6 0.0 0.087 12.6 0.0 2.1 1 1 0 1 1 1 1 Lysine methyltransferase Ubie_methyltran PF01209.18 KXL42212.1 - 0.0061 15.9 0.0 0.15 11.4 0.0 2.6 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KXL42212.1 - 0.016 14.5 0.0 0.043 13.1 0.0 1.8 1 1 0 1 1 1 0 O-methyltransferase domain MTS PF05175.14 KXL42212.1 - 0.027 14.0 0.0 0.082 12.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_2 PF00891.18 KXL42213.1 - 3.4e-21 75.5 0.0 6.3e-21 74.6 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase domain Acetyltransf_2 PF00797.17 KXL42214.1 - 3.9e-08 33.4 5.4 2.2e-06 27.7 5.4 2.9 1 1 0 1 1 1 1 N-acetyltransferase TSGP1 PF07771.11 KXL42214.1 - 2.4 8.3 7.8 2.9 8.0 0.0 2.2 2 0 0 2 2 2 0 Tick salivary peptide group 1 Aminotran_3 PF00202.21 KXL42215.1 - 4.8e-115 384.5 0.0 6e-115 384.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KXL42215.1 - 0.00071 18.8 0.0 0.0013 18.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Fungal_trans PF04082.18 KXL42216.1 - 5.3e-31 107.6 0.0 7.5e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL42216.1 - 3.4e-07 30.3 10.3 3.4e-07 30.3 10.3 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ANAPC4_WD40 PF12894.7 KXL42217.1 - 1.3e-06 28.6 0.3 0.00053 20.2 0.1 3.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Sec16_C PF12931.7 KXL42217.1 - 5.1e-05 23.1 2.2 0.00035 20.3 2.2 2.0 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 eIF2A PF08662.11 KXL42217.1 - 5.3e-05 23.2 0.3 0.00081 19.3 0.0 2.7 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 KXL42217.1 - 0.00014 22.5 3.8 3.9 8.5 0.0 5.4 6 0 0 6 6 6 2 WD domain, G-beta repeat Prp18 PF02840.15 KXL42217.1 - 0.0035 17.4 0.9 0.065 13.3 0.0 2.3 2 0 0 2 2 2 1 Prp18 domain RRM_1 PF00076.22 KXL42218.1 - 3e-17 62.2 0.0 4e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXL42218.1 - 0.0065 16.1 0.0 0.013 15.1 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KXL42218.1 - 0.015 15.4 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 Limkain b1 RRM_7 PF16367.5 KXL42218.1 - 0.016 15.4 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif Fungal_trans_2 PF11951.8 KXL42219.1 - 4.3e-55 187.1 0.0 8.6e-55 186.1 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL42219.1 - 1.9e-07 31.1 8.2 3.9e-07 30.1 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EthD PF07110.11 KXL42219.1 - 0.038 15.1 0.6 5.5 8.2 0.0 3.3 3 0 0 3 3 3 0 EthD domain adh_short_C2 PF13561.6 KXL42220.1 - 8.4e-13 48.4 0.5 1.5e-12 47.6 0.5 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL42220.1 - 4.6e-11 42.5 0.0 6.4e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase VCPO_N PF17897.1 KXL42220.1 - 0.046 13.5 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 Vanadium chloroperoxidase N-terminal domain Glyco_tran_WecB PF03808.13 KXL42220.1 - 0.069 13.1 0.1 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Prefoldin PF02996.17 KXL42222.1 - 8.8e-24 83.7 0.2 1.2e-23 83.2 0.2 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KXL42222.1 - 0.00056 19.8 1.9 0.6 10.1 0.2 2.1 2 0 0 2 2 2 2 Prefoldin subunit Fib_alpha PF08702.10 KXL42222.1 - 0.0088 16.2 1.4 1.4 9.1 0.1 2.1 2 0 0 2 2 2 2 Fibrinogen alpha/beta chain family Prominin PF05478.11 KXL42222.1 - 0.0094 14.0 0.4 0.013 13.5 0.4 1.2 1 0 0 1 1 1 1 Prominin DUF1664 PF07889.12 KXL42222.1 - 0.01 15.8 1.7 0.25 11.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Cep57_MT_bd PF06657.13 KXL42222.1 - 0.017 15.6 0.4 0.066 13.7 0.1 2.0 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 GIT_CC PF16559.5 KXL42222.1 - 0.026 14.4 0.6 0.059 13.2 0.6 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor BLOC1_2 PF10046.9 KXL42222.1 - 0.046 14.0 0.6 3.9 7.8 0.1 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PHM7_cyt PF14703.6 KXL42222.1 - 0.12 12.6 0.1 0.24 11.6 0.1 1.5 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Tropomyosin_1 PF12718.7 KXL42222.1 - 0.12 12.5 1.6 8.9 6.5 0.1 2.1 2 0 0 2 2 2 0 Tropomyosin like LPP PF04728.13 KXL42222.1 - 0.61 10.5 3.3 1.9 8.9 0.4 2.3 2 0 0 2 2 2 0 Lipoprotein leucine-zipper SKA1 PF07160.12 KXL42222.1 - 1.2 8.9 4.7 2.9 7.7 0.2 2.0 1 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 bZIP_2 PF07716.15 KXL42223.1 - 0.00019 21.4 2.4 0.00032 20.7 2.4 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KXL42223.1 - 0.00024 21.1 2.0 0.00038 20.5 2.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor Aminotran_4 PF01063.19 KXL42225.1 - 6.6e-25 88.3 0.0 8.6e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Pkinase PF00069.25 KXL42226.1 - 2e-14 53.6 0.0 1.2e-11 44.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXL42226.1 - 2.6e-06 26.9 0.0 1e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase DDE_1 PF03184.19 KXL42227.1 - 1e-08 35.0 0.0 1.1e-08 35.0 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Fungal_trans PF04082.18 KXL42228.1 - 2.9e-14 52.7 0.0 6e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL42228.1 - 3.9e-09 36.5 9.3 6.4e-09 35.8 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CK_II_beta PF01214.18 KXL42229.1 - 3.1e-77 258.5 0.0 6.9e-77 257.4 0.0 1.6 1 1 0 1 1 1 1 Casein kinase II regulatory subunit DNA_pol_phi PF04931.13 KXL42229.1 - 1.2 7.2 4.3 1.8 6.5 4.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 KXL42229.1 - 7.6 5.0 7.4 15 4.0 7.4 1.5 1 1 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 S-methyl_trans PF02574.16 KXL42230.1 - 8.1e-77 258.6 0.0 9.1e-77 258.5 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Melittin PF01372.17 KXL42230.1 - 0.11 12.4 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Melittin Ribosomal_L6 PF00347.23 KXL42231.1 - 2.2e-26 92.3 4.1 1.5e-14 54.4 0.9 2.4 2 0 0 2 2 2 2 Ribosomal protein L6 GDI PF00996.18 KXL42233.1 - 2.3e-28 98.9 0.0 2.5e-27 95.5 0.0 2.0 1 1 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 KXL42233.1 - 0.018 15.3 0.1 0.071 13.3 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Acyl-CoA_dh_M PF02770.19 KXL42234.1 - 3.4e-06 27.2 0.0 1.7e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain ACOX PF01756.19 KXL42234.1 - 0.0038 16.8 0.0 0.008 15.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KXL42234.1 - 0.016 15.8 1.3 5.8 7.5 0.1 2.9 2 1 1 3 3 3 0 Acyl-coenzyme A oxidase N-terminal STAT1_TAZ2bind PF12162.8 KXL42234.1 - 0.44 10.2 2.2 0.95 9.1 2.2 1.5 1 0 0 1 1 1 0 STAT1 TAZ2 binding domain Zn_clus PF00172.18 KXL42235.1 - 1.1e-05 25.5 11.9 1.6e-05 24.9 11.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_16 PF00722.21 KXL42238.1 - 8.5e-16 57.9 0.1 1.7e-15 57.0 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Arteri_env PF01606.16 KXL42239.1 - 0.079 12.8 0.2 0.085 12.7 0.2 1.1 1 0 0 1 1 1 0 Arterivirus envelope protein Glyco_trans_2_3 PF13632.6 KXL42240.1 - 1e-50 172.5 1.1 1e-50 172.5 1.1 2.4 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KXL42240.1 - 8.5e-06 25.7 0.0 0.00022 21.1 0.0 2.5 2 1 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KXL42240.1 - 0.00055 19.5 0.0 0.001 18.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 C_Hendra PF16821.5 KXL42240.1 - 0.08 12.8 0.5 0.15 11.9 0.5 1.4 1 0 0 1 1 1 0 C protein from hendra and measles viruses COesterase PF00135.28 KXL42241.1 - 1.5e-47 162.7 0.0 2.3e-47 162.1 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXL42241.1 - 1.1e-09 38.5 0.2 1.7e-08 34.6 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXL42241.1 - 0.01 15.4 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KXL42241.1 - 0.041 14.5 0.0 0.077 13.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lactamase_B PF00753.27 KXL42242.1 - 0.00094 19.2 0.1 0.0018 18.3 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXL42242.1 - 0.012 15.2 0.1 0.018 14.5 0.1 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain ADH_N PF08240.12 KXL42243.1 - 5.5e-24 84.1 0.9 1e-23 83.3 0.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXL42243.1 - 1e-16 61.1 0.1 1.8e-16 60.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXL42243.1 - 9.4e-05 23.5 0.0 0.00031 21.8 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXL42243.1 - 0.0004 19.7 1.6 0.00058 19.2 1.6 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 KXL42243.1 - 0.0024 17.3 0.1 0.0046 16.4 0.1 1.4 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 KXL42243.1 - 0.011 16.0 0.4 0.018 15.3 0.4 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 KXL42243.1 - 0.049 13.0 0.1 0.08 12.3 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KXL42243.1 - 0.05 13.9 0.1 0.093 13.0 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain AMP-binding PF00501.28 KXL42244.1 - 1.2e-62 212.0 0.0 1.5e-62 211.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXL42244.1 - 0.00049 21.0 0.0 0.00096 20.1 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Mpv17_PMP22 PF04117.12 KXL42245.1 - 1.1e-21 76.9 0.3 2.2e-21 75.8 0.3 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF3341 PF11821.8 KXL42245.1 - 0.02 14.5 0.9 0.03 14.0 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) DUF1576 PF07613.11 KXL42245.1 - 0.025 14.1 0.3 0.037 13.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1576) Hexokinase_2 PF03727.16 KXL42246.1 - 6.3e-78 261.5 0.0 8.7e-78 261.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KXL42246.1 - 4.8e-75 251.8 0.2 8e-75 251.1 0.2 1.4 1 0 0 1 1 1 1 Hexokinase Bac_DNA_binding PF00216.21 KXL42246.1 - 0.12 12.6 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 Bacterial DNA-binding protein YhdB PF14148.6 KXL42246.1 - 0.14 12.2 0.4 0.42 10.8 0.4 1.8 1 0 0 1 1 1 0 YhdB-like protein adh_short PF00106.25 KXL42248.1 - 5.5e-13 48.8 0.0 5.1e-12 45.7 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL42248.1 - 9.4e-07 28.6 0.0 2.8e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL42248.1 - 0.00017 21.5 0.0 0.00029 20.8 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXL42248.1 - 0.11 12.4 0.3 0.19 11.6 0.3 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Aldedh PF00171.22 KXL42251.1 - 3.1e-112 375.4 0.0 3.9e-112 375.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Redoxin PF08534.10 KXL42252.1 - 2.2e-35 121.5 0.0 2.5e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KXL42252.1 - 1.8e-09 37.6 0.0 2e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF2550 PF10739.9 KXL42253.1 - 0.064 13.3 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2550) Sec10 PF07393.11 KXL42254.1 - 0.13 10.6 0.0 0.13 10.6 0.0 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec10 Methyltransf_23 PF13489.6 KXL42255.1 - 4.6e-22 78.6 0.0 7.3e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL42255.1 - 4.4e-13 49.8 0.0 1.7e-12 47.8 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL42255.1 - 7.5e-13 48.5 0.0 1e-05 25.4 0.0 2.5 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KXL42255.1 - 8.8e-12 45.5 0.0 1.8e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL42255.1 - 5.9e-07 30.2 0.0 4.3e-06 27.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXL42255.1 - 1.4e-05 24.5 0.0 0.00022 20.6 0.0 2.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KXL42255.1 - 2.4e-05 23.8 0.0 3.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 KXL42255.1 - 4e-05 23.0 0.0 0.038 13.3 0.0 2.1 2 0 0 2 2 2 2 O-methyltransferase domain Methyltransf_4 PF02390.17 KXL42255.1 - 0.001 18.6 0.0 0.0024 17.4 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KXL42255.1 - 0.0044 16.6 0.0 0.013 15.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KXL42255.1 - 0.045 13.9 0.0 0.37 10.9 0.0 2.0 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 KXL42255.1 - 0.055 13.2 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 KXL42255.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF3173 PF11372.8 KXL42255.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3173) MFS_1 PF07690.16 KXL42256.1 - 1.5e-39 136.0 15.1 1.5e-39 136.0 15.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL42256.1 - 1.4e-07 30.8 10.9 1.4e-07 30.8 10.9 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXL42256.1 - 2.4e-05 23.0 1.5 3.5e-05 22.4 1.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ribosomal_L24e PF01246.20 KXL42257.1 - 4.1e-27 94.2 0.4 4.1e-27 94.2 0.4 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e Ribosomal_L14e PF01929.17 KXL42258.1 - 7.5e-31 106.5 0.3 1.1e-30 105.9 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 KXL42258.1 - 0.13 12.3 0.1 0.27 11.2 0.1 1.6 1 0 0 1 1 1 0 KOW motif NAC PF01849.18 KXL42259.1 - 3.7e-23 81.3 0.1 1.6e-22 79.2 0.0 2.0 2 0 0 2 2 2 1 NAC domain RNA_pol_Rpo13 PF12136.8 KXL42259.1 - 0.096 12.6 4.7 0.085 12.8 2.9 1.9 2 0 0 2 2 2 0 RNA polymerase Rpo13 subunit HTH domain Myc_N PF01056.18 KXL42259.1 - 1.1 9.1 6.6 1.4 8.7 6.5 1.3 1 1 0 1 1 1 0 Myc amino-terminal region Mt_ATP-synt_D PF05873.12 KXL42260.1 - 3.9e-23 82.0 5.0 5e-23 81.6 5.0 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) NOG1_N PF17835.1 KXL42260.1 - 0.0022 18.0 2.0 0.0035 17.3 2.0 1.3 1 0 0 1 1 1 1 NOG1 N-terminal helical domain GIDA_assoc PF13932.6 KXL42260.1 - 0.0022 18.2 1.8 0.0028 17.9 1.8 1.1 1 0 0 1 1 1 1 GidA associated domain SHE3 PF17078.5 KXL42260.1 - 0.0041 16.9 3.0 0.0054 16.5 3.0 1.1 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 Laminin_II PF06009.12 KXL42260.1 - 0.01 15.9 5.2 0.24 11.4 2.9 2.4 2 0 0 2 2 2 0 Laminin Domain II DUF148 PF02520.17 KXL42260.1 - 0.011 15.9 7.8 0.011 15.9 7.8 1.6 2 1 0 2 2 1 0 Domain of unknown function DUF148 Phage_30_3 PF08010.11 KXL42260.1 - 0.068 13.0 1.1 2.3 8.0 0.0 2.2 1 1 1 2 2 2 0 Bacteriophage protein GP30.3 TPR_MLP1_2 PF07926.12 KXL42260.1 - 0.12 12.4 10.9 1.7 8.7 1.0 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF16 PF01519.16 KXL42260.1 - 0.14 12.7 5.6 0.24 11.9 5.6 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 Vps51 PF08700.11 KXL42260.1 - 0.15 12.2 5.7 3.7 7.7 5.7 2.4 1 1 0 1 1 1 0 Vps51/Vps67 DUF2408 PF10303.9 KXL42260.1 - 0.15 12.6 3.6 0.14 12.7 2.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Herpes_TK_C PF08465.10 KXL42260.1 - 0.17 11.7 1.9 2.3 8.0 0.1 2.8 2 1 0 2 2 2 0 Thymidine kinase from Herpesvirus C-terminal TMPIT PF07851.13 KXL42260.1 - 0.3 10.3 5.1 0.38 9.9 5.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein XhlA PF10779.9 KXL42260.1 - 1.2 9.4 5.7 4.9 7.4 3.1 2.5 1 1 1 2 2 2 0 Haemolysin XhlA Fib_alpha PF08702.10 KXL42260.1 - 1.9 8.7 6.9 2.5 8.3 4.6 2.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family PhoU PF01895.19 KXL42260.1 - 2.4 8.7 5.8 9 6.8 0.4 2.5 1 1 1 2 2 2 0 PhoU domain CLZ PF16526.5 KXL42260.1 - 3.4 8.1 6.4 1.5 9.2 1.4 2.6 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BLOC1_2 PF10046.9 KXL42260.1 - 4 7.8 9.1 3.9 7.8 6.3 2.1 2 1 1 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6_N PF17675.1 KXL42260.1 - 4.1 7.9 10.0 11 6.5 10.0 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region Seryl_tRNA_N PF02403.22 KXL42260.1 - 4.5 7.5 11.2 2.3 8.5 7.6 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Glyco_hydro_31 PF01055.26 KXL42261.1 - 6.7e-90 302.4 0.2 8.1e-90 302.1 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KXL42261.1 - 4.6e-10 39.7 0.3 2.7e-09 37.2 0.0 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like MFS_1 PF07690.16 KXL42262.1 - 1.4e-27 96.6 28.5 1.4e-27 96.6 28.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily WH1 PF00568.23 KXL42263.1 - 1.6e-24 86.0 0.1 2.2e-24 85.5 0.1 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 KXL42263.1 - 1.4e-07 31.1 0.7 3.4e-07 29.9 0.7 1.6 1 0 0 1 1 1 1 WH2 motif eIF-1a PF01176.19 KXL42264.1 - 3.3e-21 74.8 0.0 4.6e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Cellulase PF00150.18 KXL42266.1 - 1.3e-47 162.6 8.3 1.6e-47 162.3 8.3 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.25 KXL42267.1 - 6.3e-76 255.2 0.0 7.3e-76 255.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL42267.1 - 5.4e-36 124.2 0.0 7.6e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXL42267.1 - 0.00035 19.6 0.0 0.0043 16.0 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KXL42267.1 - 0.014 14.7 0.0 0.046 13.1 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXL42267.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KXL42267.1 - 0.039 13.3 0.0 0.084 12.2 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.11 KXL42267.1 - 0.13 11.2 0.0 0.32 10.0 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 CBP4 PF07960.11 KXL42268.1 - 1.7e-28 99.0 0.5 1.9e-28 98.9 0.5 1.0 1 0 0 1 1 1 1 CBP4 ERCC4 PF02732.15 KXL42269.1 - 1.7e-18 67.3 0.0 3.9e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 ERCC4 domain HHH_2 PF12826.7 KXL42269.1 - 0.014 15.5 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_5 PF14520.6 KXL42269.1 - 0.17 12.5 0.0 0.58 10.8 0.0 1.8 1 1 0 1 1 1 0 Helix-hairpin-helix domain RRM_1 PF00076.22 KXL42270.1 - 1.3e-32 111.5 0.3 1.6e-17 63.1 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KXL42270.1 - 0.00084 19.4 0.4 0.78 9.9 0.0 3.3 3 0 0 3 3 3 1 Limkain b1 RRM_5 PF13893.6 KXL42270.1 - 0.0031 17.1 0.0 2.2 7.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.12 KXL42270.1 - 0.079 12.7 0.5 0.31 10.8 0.0 2.2 3 0 0 3 3 3 0 Calcipressin WES_acyltransf PF03007.16 KXL42270.1 - 0.12 12.1 1.9 0.28 10.9 1.0 1.9 2 0 0 2 2 2 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Nup35_RRM_2 PF14605.6 KXL42270.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif PIP5K PF01504.18 KXL42271.1 - 7.8e-49 166.3 0.0 1.9e-48 165.0 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Wbp11 PF09429.10 KXL42272.1 - 2.1e-20 72.9 16.3 2.1e-20 72.9 16.3 3.1 3 0 0 3 3 3 1 WW domain binding protein 11 RP-C_C PF11800.8 KXL42272.1 - 0.011 15.9 4.9 0.011 15.9 4.9 2.3 2 1 1 3 3 3 0 Replication protein C C-terminal region ADH_N_2 PF16884.5 KXL42273.1 - 1.5e-24 86.0 0.0 2.7e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KXL42273.1 - 1.7e-19 70.1 0.0 2.7e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXL42273.1 - 2e-07 32.1 0.0 3.4e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MFS_1 PF07690.16 KXL42274.1 - 2.7e-22 79.2 27.9 2.7e-22 79.2 27.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Pex24p PF06398.11 KXL42274.1 - 0.053 12.5 0.2 0.096 11.7 0.2 1.4 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Ldr_toxin PF13940.6 KXL42274.1 - 0.51 10.4 3.0 2.7 8.1 0.1 3.4 3 0 0 3 3 3 0 Toxin Ldr, type I toxin-antitoxin system TRI12 PF06609.13 KXL42275.1 - 1.3e-45 156.0 20.4 1.6e-45 155.6 20.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KXL42275.1 - 7e-21 74.5 45.1 7e-21 74.5 45.1 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL42275.1 - 3.4e-11 42.7 12.9 3.4e-11 42.7 12.9 3.3 4 0 0 4 4 4 1 Sugar (and other) transporter E1-E2_ATPase PF00122.20 KXL42276.1 - 2.3e-44 151.1 3.8 2.3e-44 151.1 3.8 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KXL42276.1 - 9.8e-22 78.3 0.1 1.9e-21 77.3 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KXL42276.1 - 5e-09 36.5 0.7 3.9e-08 33.6 0.1 2.8 3 0 0 3 3 3 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KXL42276.1 - 0.00089 19.1 0.4 0.0066 16.2 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Fungal_trans PF04082.18 KXL42277.1 - 1.6e-16 60.2 0.6 2.8e-16 59.4 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL42277.1 - 3.5e-14 52.6 29.4 8.8e-09 35.4 13.5 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KXL42278.1 - 1.8e-77 261.2 19.5 2e-77 261.0 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL42278.1 - 2.1e-27 96.0 23.6 4.2e-18 65.4 8.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXL42278.1 - 1.2e-05 24.0 15.5 2.3e-05 23.2 3.6 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein Sulfatase PF00884.23 KXL42279.1 - 2.2e-44 152.1 0.0 3e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KXL42279.1 - 4.2e-05 23.3 0.0 0.00039 20.1 0.0 2.0 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 KXL42279.1 - 0.00064 20.0 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) Mucin PF01456.17 KXL42282.1 - 0.0005 20.1 8.2 0.00069 19.6 8.2 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein Dicty_REP PF05086.12 KXL42282.1 - 0.39 8.6 5.7 0.43 8.5 5.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.8 KXL42282.1 - 1.3 9.0 12.6 1.9 8.5 12.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 KXL42282.1 - 1.9 6.6 14.4 2.5 6.2 14.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 GCP_C_terminal PF04130.13 KXL42284.1 - 1.4e-97 326.9 0.0 2.4e-97 326.1 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KXL42284.1 - 1.2e-81 274.7 0.0 8.4e-81 271.9 0.0 2.0 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal Aft1_HRR PF11787.8 KXL42285.1 - 2.2e-24 86.4 6.2 2.2e-24 86.4 6.2 5.4 4 2 1 5 5 5 1 Aft1 HRR domain Aft1_HRA PF11786.8 KXL42285.1 - 1.5e-20 73.3 11.3 1.5e-20 73.3 11.3 3.2 2 1 1 3 3 3 1 Aft1 HRA domain bZIP_1 PF00170.21 KXL42285.1 - 2.8e-13 49.8 3.3 4.7e-13 49.0 3.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor Aft1_OSA PF11785.8 KXL42285.1 - 5.9e-11 42.6 8.1 5.9e-11 42.6 8.1 3.5 4 0 0 4 4 4 1 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.15 KXL42285.1 - 5.3e-06 26.4 6.2 9.5e-06 25.6 6.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KXL42285.1 - 0.0029 18.1 1.8 0.0029 18.1 1.8 1.9 2 0 0 2 2 2 1 bZIP Maf transcription factor Nnf1 PF03980.14 KXL42285.1 - 0.11 12.9 1.7 0.22 11.9 1.7 1.5 1 0 0 1 1 1 0 Nnf1 DUF4692 PF15763.5 KXL42285.1 - 1.5 9.3 3.6 4.5 7.7 3.6 1.8 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) TPR_1 PF00515.28 KXL42286.1 - 3.1e-36 121.7 34.5 2.2e-05 24.0 0.0 11.9 12 0 0 12 12 11 7 Tetratricopeptide repeat TPR_2 PF07719.17 KXL42286.1 - 7.8e-33 109.9 35.0 0.00049 20.0 0.1 12.4 12 0 0 12 12 12 7 Tetratricopeptide repeat TPR_11 PF13414.6 KXL42286.1 - 2.8e-21 74.9 23.4 0.00046 19.8 0.0 9.0 6 2 3 9 9 9 6 TPR repeat TPR_17 PF13431.6 KXL42286.1 - 2.2e-19 68.4 14.1 0.00011 22.4 0.0 8.6 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXL42286.1 - 1.7e-18 65.2 29.0 0.023 14.9 0.1 11.0 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_16 PF13432.6 KXL42286.1 - 6.1e-17 62.0 27.7 0.00025 21.6 0.1 8.7 6 3 3 10 10 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 KXL42286.1 - 2.9e-12 46.7 28.4 0.0031 17.8 0.5 8.2 4 2 4 8 8 8 4 Tetratricopeptide repeat TPR_9 PF13371.6 KXL42286.1 - 6.1e-12 45.5 8.2 9.6e-05 22.5 0.6 5.6 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXL42286.1 - 1.2e-08 34.3 18.8 0.048 13.7 0.1 8.5 9 1 1 10 10 9 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXL42286.1 - 2.8e-08 33.9 13.3 0.031 15.1 0.3 8.5 5 3 4 9 9 8 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXL42286.1 - 3.2e-08 34.0 25.2 0.00011 22.7 1.3 7.0 6 2 0 7 7 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 KXL42286.1 - 6.7e-06 25.8 22.9 0.028 14.3 0.2 7.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KXL42286.1 - 3.1e-05 23.5 1.8 3.1e-05 23.5 1.8 2.4 1 1 1 2 2 2 1 MalT-like TPR region ANAPC3 PF12895.7 KXL42286.1 - 0.00036 20.7 15.9 0.17 12.1 0.6 5.1 3 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 KXL42286.1 - 0.0061 16.6 4.8 4.6 7.3 0.0 4.8 4 1 1 5 5 5 1 Domain of Unknown Function (DUF3856) TAF1_subA PF14929.6 KXL42286.1 - 0.058 12.8 1.5 0.11 11.8 0.2 2.0 3 0 0 3 3 3 0 TAF RNA Polymerase I subunit A MAS20 PF02064.15 KXL42286.1 - 0.08 13.0 12.6 0.54 10.3 0.2 4.9 4 1 1 5 5 5 0 MAS20 protein import receptor DUF3808 PF10300.9 KXL42286.1 - 0.12 11.1 6.1 0.43 9.2 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3808) Alkyl_sulf_dimr PF14863.6 KXL42286.1 - 0.13 12.7 2.4 9.1 6.7 0.1 4.0 2 1 1 3 3 3 0 Alkyl sulfatase dimerisation IPPT PF01715.17 KXL42286.1 - 0.13 12.0 1.5 0.41 10.4 0.0 2.5 3 0 0 3 3 3 0 IPP transferase MIT PF04212.18 KXL42286.1 - 0.16 12.1 23.7 13 5.9 0.1 6.2 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain Sel1 PF08238.12 KXL42286.1 - 0.47 11.2 7.8 1.6 9.5 0.0 4.2 4 0 0 4 4 3 0 Sel1 repeat SHNi-TPR PF10516.9 KXL42286.1 - 0.51 9.8 19.3 2 7.9 0.2 6.4 7 0 0 7 7 7 0 SHNi-TPR TPR_6 PF13174.6 KXL42286.1 - 3.3 8.5 0.0 3.3 8.5 0.0 8.3 11 0 0 11 11 7 0 Tetratricopeptide repeat HemY_N PF07219.13 KXL42286.1 - 4.2 7.6 7.4 30 4.9 0.8 4.1 3 1 1 4 4 4 0 HemY protein N-terminus WD40 PF00400.32 KXL42287.1 - 3.1e-47 157.6 24.3 5e-09 36.6 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL42287.1 - 2.7e-09 37.2 0.3 0.051 13.9 0.0 4.5 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXL42287.1 - 1.2e-05 24.2 4.1 0.073 11.7 0.1 4.7 2 1 3 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KXL42287.1 - 0.0016 17.5 0.0 4 6.3 0.0 3.8 1 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KXL42287.1 - 0.012 15.0 0.0 0.96 8.7 0.0 2.6 2 1 0 3 3 3 0 WD40-like domain PD40 PF07676.12 KXL42287.1 - 0.024 14.6 0.7 22 5.1 0.0 4.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Plus-3 PF03126.18 KXL42288.1 - 3e-29 101.7 0.0 6.1e-29 100.7 0.0 1.6 1 0 0 1 1 1 1 Plus-3 domain MTBP_mid PF14919.6 KXL42288.1 - 1.5 8.0 5.5 1.5 8.0 1.7 2.0 2 0 0 2 2 2 0 MDM2-binding COQ7 PF03232.13 KXL42289.1 - 7.2e-69 231.0 1.1 9.9e-69 230.5 1.1 1.2 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 KXL42289.1 - 3.4e-05 24.3 0.0 6.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Rubrerythrin Crr6 PF08847.11 KXL42289.1 - 0.02 14.5 0.1 0.13 11.9 0.0 1.9 1 1 1 2 2 2 0 Chlororespiratory reduction 6 DUF4455 PF14643.6 KXL42289.1 - 0.059 12.0 0.2 0.082 11.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) PsbQ PF05757.11 KXL42289.1 - 0.29 10.9 2.3 0.7 9.6 2.3 1.7 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) SRAP PF02586.14 KXL42290.1 - 4e-77 258.7 0.0 5.5e-77 258.2 0.0 1.2 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) TPR_12 PF13424.6 KXL42291.1 - 3.1e-09 37.0 12.8 0.00037 20.7 2.5 4.4 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 KXL42291.1 - 2.7e-05 24.0 16.3 0.011 15.8 0.7 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXL42291.1 - 0.00061 19.6 4.8 1.4 9.1 0.3 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat RPN7 PF10602.9 KXL42291.1 - 0.00081 19.1 0.2 0.002 17.9 0.0 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 TPR_8 PF13181.6 KXL42291.1 - 0.027 14.7 6.8 2.3 8.7 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXL42291.1 - 0.029 14.2 9.3 0.64 9.9 0.8 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXL42291.1 - 0.032 14.8 0.4 0.032 14.8 0.4 3.7 4 1 1 5 5 3 0 Tetratricopeptide repeat PriCT_1 PF08708.11 KXL42291.1 - 0.16 11.7 0.9 40 4.0 0.0 3.7 4 0 0 4 4 4 0 Primase C terminal 1 (PriCT-1) TPR_19 PF14559.6 KXL42291.1 - 0.36 11.4 8.3 3.9 8.0 0.2 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXL42291.1 - 0.57 10.1 18.1 0.19 11.7 1.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXL42291.1 - 1.5 9.9 20.2 5.1 8.2 1.0 5.5 5 1 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 KXL42291.1 - 5 7.3 6.1 13 5.9 0.6 3.6 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain G_glu_transpept PF01019.21 KXL42292.1 - 2.4e-139 465.4 0.0 2.8e-139 465.2 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Isochorismatase PF00857.20 KXL42293.1 - 6.4e-27 94.9 0.0 6.7e-26 91.5 0.0 2.2 1 1 0 1 1 1 1 Isochorismatase family 2OG-FeII_Oxy_2 PF13532.6 KXL42293.1 - 1.1e-23 84.5 0.0 1.9e-23 83.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GFA PF04828.14 KXL42295.1 - 7.8e-25 87.1 0.0 1.1e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Tfb5 PF06331.12 KXL42296.1 - 7.6e-23 80.3 1.8 8.3e-23 80.2 1.8 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 UTP15_C PF09384.10 KXL42297.1 - 1.8e-41 141.3 0.0 2.7e-41 140.7 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 KXL42297.1 - 2.1e-13 50.5 10.8 0.0024 18.6 0.2 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL42297.1 - 3.2e-06 27.3 1.1 0.1 12.9 0.0 4.1 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KXL42297.1 - 2.9 8.5 5.9 44 4.7 0.1 3.6 4 0 0 4 4 4 0 PQQ-like domain TauD PF02668.16 KXL42298.1 - 6.9e-31 108.0 0.0 9.3e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-Fe_Oxy_2 PF10014.9 KXL42298.1 - 0.11 12.3 0.3 1.1 9.0 0.1 2.3 2 1 0 2 2 2 0 2OG-Fe dioxygenase Fungal_trans PF04082.18 KXL42299.1 - 1.1e-20 73.8 0.2 1.9e-20 73.1 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL42299.1 - 2.3e-14 53.2 34.5 2.4e-07 30.7 12.9 2.7 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KXL42300.1 - 5.3e-79 266.2 17.7 6.1e-79 266.0 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL42300.1 - 7.4e-14 51.4 8.8 7.4e-14 51.4 8.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Pox_P21 PF05313.12 KXL42300.1 - 0.0012 18.4 2.1 0.0026 17.4 2.1 1.5 1 0 0 1 1 1 1 Poxvirus P21 membrane protein Trp_oprn_chp PF09534.10 KXL42300.1 - 0.26 11.1 2.4 1.7 8.4 0.2 2.3 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SKG6 PF08693.10 KXL42301.1 - 0.00034 20.0 0.5 0.00073 18.9 0.5 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Methyltransf_23 PF13489.6 KXL42302.1 - 5.6e-18 65.3 0.0 1e-17 64.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL42302.1 - 9.4e-14 51.8 0.0 3.5e-13 50.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL42302.1 - 3.6e-13 50.0 0.0 9.9e-13 48.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL42302.1 - 1.3e-09 38.1 0.0 6.6e-09 35.7 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL42302.1 - 4.6e-08 33.7 0.0 9.7e-07 29.5 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXL42302.1 - 6.5e-05 22.4 0.0 0.00015 21.2 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KXL42302.1 - 0.0006 19.3 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.20 KXL42302.1 - 0.01 15.2 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.14 KXL42302.1 - 0.013 15.0 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 KXL42302.1 - 0.033 13.6 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 KXL42302.1 - 0.034 13.9 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 KXL42302.1 - 0.04 14.0 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Tma16 PF11176.8 KXL42302.1 - 0.071 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Translation machinery-associated protein 16 Methyltransf_9 PF08003.11 KXL42302.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Dus PF01207.17 KXL42303.1 - 5.8e-61 206.3 0.0 4.2e-60 203.4 0.0 2.2 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Mitofilin PF09731.9 KXL42303.1 - 0.0013 17.7 1.2 0.0017 17.3 1.2 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein FMN_dh PF01070.18 KXL42303.1 - 0.03 13.4 0.0 0.064 12.3 0.0 1.5 1 0 0 1 1 1 0 FMN-dependent dehydrogenase USP19_linker PF16602.5 KXL42303.1 - 0.059 13.9 2.1 6.7 7.3 0.1 2.4 2 0 0 2 2 2 0 Linker region of USP19 deubiquitinase Brr6_like_C_C PF10104.9 KXL42303.1 - 0.063 13.1 0.3 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain Ribosomal_S13 PF00416.22 KXL42304.1 - 7.2e-55 184.8 2.8 8.4e-55 184.6 2.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 KXL42304.1 - 0.017 13.9 0.0 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Ribosomal_S25 PF03297.15 KXL42305.1 - 1.8e-37 127.6 5.4 1.9e-37 127.5 5.4 1.0 1 0 0 1 1 1 1 S25 ribosomal protein YscJ_FliF_C PF08345.11 KXL42305.1 - 0.018 15.4 1.0 0.032 14.6 1.0 1.4 1 1 0 1 1 1 0 Flagellar M-ring protein C-terminal HTH_24 PF13412.6 KXL42305.1 - 0.064 12.8 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Glyco_hydro_15 PF00723.21 KXL42305.1 - 0.074 11.8 0.0 0.077 11.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 15 MarR_2 PF12802.7 KXL42305.1 - 0.12 12.3 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 MarR family Arf PF00025.21 KXL42306.1 - 1e-39 135.8 0.1 6.9e-27 94.0 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 KXL42306.1 - 2e-14 53.5 0.0 7.1e-08 32.0 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KXL42306.1 - 6.5e-11 42.5 0.0 2.5e-10 40.6 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KXL42306.1 - 2.7e-09 36.8 0.0 1.6e-05 24.6 0.0 2.1 2 0 0 2 2 2 2 Ras family SRPRB PF09439.10 KXL42306.1 - 5.6e-07 29.2 0.0 6.1e-06 25.8 0.0 2.0 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KXL42306.1 - 1.1e-06 28.2 0.0 1.4e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXL42306.1 - 1.4e-05 25.1 0.0 2.8e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXL42306.1 - 0.00045 19.8 0.0 0.059 12.9 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KXL42306.1 - 0.0051 16.3 0.0 0.011 15.3 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 KXL42306.1 - 0.041 14.3 0.1 0.25 11.7 0.0 2.0 1 1 1 2 2 2 0 AAA ATPase domain TniB PF05621.11 KXL42306.1 - 0.048 13.1 0.0 0.081 12.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Thymidylate_kin PF02223.17 KXL42306.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase Sugar_tr PF00083.24 KXL42307.1 - 5.5e-93 312.3 30.9 6.4e-93 312.1 30.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL42307.1 - 8.1e-24 84.2 64.8 1.7e-17 63.4 35.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_6 PF12697.7 KXL42308.1 - 2.8e-06 28.1 3.4 3.9e-06 27.6 3.4 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PTB PF08416.13 KXL42308.1 - 0.0031 17.6 0.0 0.0048 17.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PGAP1 PF07819.13 KXL42308.1 - 0.0044 16.8 0.0 0.0095 15.7 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 KXL42308.1 - 0.0057 16.3 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold HSP70 PF00012.20 KXL42309.1 - 5.8e-11 41.3 0.6 2e-09 36.2 0.2 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KXL42309.1 - 0.015 14.2 0.1 0.12 11.1 0.0 2.0 2 0 0 2 2 2 0 MreB/Mbl protein Gtr1_RagA PF04670.12 KXL42311.1 - 2e-42 145.1 0.0 5.8e-42 143.6 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Glyco_tran_28_C PF04101.16 KXL42312.1 - 1.4e-16 61.0 0.0 8.2e-13 48.7 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 KXL42312.1 - 0.27 10.0 0.0 0.45 9.2 0.0 1.3 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase MRP-S28 PF10213.9 KXL42313.1 - 6.4e-41 139.7 0.0 1.2e-40 138.9 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein CALM_bind PF16025.5 KXL42313.1 - 0.33 11.4 5.3 0.65 10.5 5.3 1.4 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding Glyco_hydro_11 PF00457.17 KXL42315.1 - 4.4e-59 199.1 5.5 5.3e-59 198.8 5.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Methyltr_RsmB-F PF01189.17 KXL42316.1 - 2.3e-20 73.1 0.0 1.9e-12 47.2 0.0 2.3 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F DUF2268 PF10026.9 KXL42318.1 - 0.092 12.3 0.0 0.1 12.2 0.0 1.0 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) CN_hydrolase PF00795.22 KXL42319.1 - 3.9e-26 92.0 0.0 4.8e-22 78.5 0.0 2.2 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase DEAD PF00270.29 KXL42321.1 - 1.8e-32 112.6 0.8 6.3e-16 58.6 0.1 2.6 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KXL42321.1 - 8.6e-12 45.4 0.0 1.3e-10 41.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL42321.1 - 7.9e-06 26.0 2.4 4.9e-05 23.4 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit MMR_HSR1_C PF08438.10 KXL42321.1 - 0.0069 16.9 0.4 0.037 14.6 0.1 2.4 2 0 0 2 2 2 1 GTPase of unknown function C-terminal NPCBM PF08305.11 KXL42321.1 - 0.052 13.7 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 NPCBM/NEW2 domain Peptidase_A17 PF05380.13 KXL42321.1 - 0.11 12.5 0.0 21 5.1 0.0 2.4 2 0 0 2 2 2 0 Pao retrotransposon peptidase PIGA PF08288.12 KXL42322.1 - 6.5e-41 138.8 0.7 6.5e-41 138.8 0.7 2.1 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 KXL42322.1 - 1.1e-25 90.6 0.7 1.8e-25 89.9 0.7 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KXL42322.1 - 3.4e-23 82.0 0.0 5.7e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXL42322.1 - 4.3e-20 72.5 0.1 7.3e-20 71.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KXL42322.1 - 7.1e-11 42.8 0.0 1.6e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KXL42322.1 - 8.8e-05 22.8 0.0 0.0002 21.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 KXL42322.1 - 0.015 15.3 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like GMC_oxred_N PF00732.19 KXL42324.1 - 1.4e-41 142.9 1.0 1.9e-41 142.4 0.3 1.6 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXL42324.1 - 2e-29 102.9 0.5 5.9e-28 98.2 0.1 2.3 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXL42324.1 - 1.6e-05 24.2 6.9 6.9e-05 22.1 6.9 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXL42324.1 - 2.1e-05 23.9 0.2 6.5e-05 22.3 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXL42324.1 - 2.6e-05 23.6 0.7 5.2e-05 22.7 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KXL42324.1 - 0.00053 19.3 0.4 0.0011 18.3 0.4 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KXL42324.1 - 0.0046 17.1 4.3 0.015 15.5 1.2 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KXL42324.1 - 0.008 15.6 1.2 0.012 15.0 1.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXL42324.1 - 0.033 12.9 1.7 0.039 12.7 0.6 1.6 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.24 KXL42324.1 - 0.12 11.9 7.7 2 7.9 7.7 2.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KXL42324.1 - 0.14 11.5 0.1 0.24 10.7 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KXL42324.1 - 0.15 11.1 0.2 0.26 10.3 0.0 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KXL42324.1 - 0.15 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FYVE PF01363.21 KXL42325.1 - 1.9e-16 59.9 7.9 3e-16 59.3 7.9 1.3 1 0 0 1 1 1 1 FYVE zinc finger Cytomega_UL84 PF06284.11 KXL42326.1 - 0.044 12.3 1.3 0.066 11.7 1.3 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein NAM-associated PF14303.6 KXL42326.1 - 0.89 10.3 11.0 2.1 9.0 11.0 1.6 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain RR_TM4-6 PF06459.12 KXL42326.1 - 2 8.2 8.2 2.5 7.8 8.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 KXL42326.1 - 2.8 6.6 4.5 3.7 6.2 4.5 1.2 1 0 0 1 1 1 0 Presenilin Herpes_US9 PF06072.11 KXL42327.1 - 0.42 10.5 1.6 1 9.3 1.6 1.7 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 HATPase_c PF02518.26 KXL42328.1 - 9.7e-21 74.4 0.0 2.4e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXL42328.1 - 4.5e-16 59.0 0.1 6.5e-15 55.3 0.0 2.9 3 1 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.25 KXL42328.1 - 8e-12 45.0 0.0 4.7e-11 42.6 0.0 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain ALO PF04030.14 KXL42329.1 - 4.2e-82 275.9 0.1 6.7e-82 275.2 0.1 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KXL42329.1 - 7e-30 103.6 0.0 1.1e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain PAP_central PF04928.17 KXL42331.1 - 1.1e-94 316.1 0.0 1.4e-94 315.7 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KXL42331.1 - 2.3e-52 177.1 0.0 3.5e-52 176.5 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KXL42331.1 - 4.9e-08 33.2 0.0 1.1e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KXL42331.1 - 0.097 12.8 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Abhydrolase_1 PF00561.20 KXL42332.1 - 1.7e-07 31.1 0.0 2.5e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXL42332.1 - 0.031 13.5 0.0 0.086 12.1 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXL42332.1 - 0.048 14.2 0.0 0.067 13.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Flavin_Reduct PF01613.18 KXL42333.1 - 8.1e-18 64.9 0.0 1.1e-17 64.5 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain APH PF01636.23 KXL42334.1 - 2e-07 31.2 0.5 2e-07 31.2 0.5 1.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KXL42334.1 - 0.01 14.7 0.0 0.014 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Sec8_exocyst PF04048.14 KXL42336.1 - 0.059 13.2 0.2 6.3 6.7 0.2 2.3 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DDE_1 PF03184.19 KXL42336.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.7 1 1 0 1 1 1 0 DDE superfamily endonuclease FMO-like PF00743.19 KXL42337.1 - 5.4e-21 74.6 0.0 1.2e-20 73.5 0.0 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXL42337.1 - 9.5e-17 61.1 0.0 2.8e-13 49.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXL42337.1 - 1.6e-10 40.7 0.0 1.5e-08 34.2 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXL42337.1 - 4.3e-10 39.7 0.1 2e-08 34.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXL42337.1 - 1.1e-09 37.9 0.0 2.9e-08 33.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXL42337.1 - 6.5e-07 29.8 0.2 0.0072 16.9 0.3 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXL42337.1 - 3e-06 27.3 0.1 1.5 8.8 0.0 4.0 3 1 1 4 4 4 2 FAD-NAD(P)-binding DAO PF01266.24 KXL42337.1 - 7.9e-05 22.4 0.7 0.22 11.0 0.0 3.3 3 1 0 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.17 KXL42337.1 - 0.0011 18.3 0.0 0.066 12.4 0.0 2.8 3 0 0 3 3 3 1 Thi4 family AlaDh_PNT_C PF01262.21 KXL42337.1 - 0.0017 17.7 0.0 0.0075 15.6 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KXL42337.1 - 0.0031 16.7 0.0 0.0047 16.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KXL42337.1 - 0.0041 16.2 0.0 1.2 8.1 0.0 2.5 3 0 0 3 3 3 2 Lycopene cyclase protein HI0933_like PF03486.14 KXL42337.1 - 0.036 12.8 0.7 0.47 9.1 0.1 2.9 4 0 0 4 4 4 0 HI0933-like protein GIDA PF01134.22 KXL42337.1 - 0.038 13.1 0.0 1.9 7.5 0.0 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A Shikimate_DH PF01488.20 KXL42337.1 - 0.043 13.9 0.1 0.48 10.5 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.7 KXL42337.1 - 0.13 11.6 0.1 0.24 10.7 0.1 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase DUF3630 PF12305.8 KXL42337.1 - 0.18 11.9 0.1 0.38 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3630) DEAD PF00270.29 KXL42340.1 - 1.2e-38 132.6 0.2 2e-38 131.9 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXL42340.1 - 1.1e-25 90.1 0.1 1.4e-22 80.2 0.0 2.6 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 KXL42340.1 - 9.2e-10 38.8 0.0 1.7e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KXL42340.1 - 0.091 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit SMC_N PF02463.19 KXL42340.1 - 0.17 11.3 0.1 0.38 10.1 0.1 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Rpr2 PF04032.16 KXL42341.1 - 2.7e-22 78.8 0.0 6.4e-22 77.6 0.0 1.7 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Mit_KHE1 PF10173.9 KXL42342.1 - 0.001 19.2 0.1 0.001 19.2 0.1 1.7 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related MBOAT PF03062.19 KXL42344.1 - 3.1e-18 66.3 13.1 3.1e-18 66.3 13.1 1.7 1 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KXL42344.1 - 3e-05 24.2 1.2 0.00012 22.3 1.2 2.1 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family PGG PF13962.6 KXL42344.1 - 0.3 10.9 6.9 0.18 11.6 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function SLC35F PF06027.12 KXL42345.1 - 1.8e-91 306.7 20.2 2.2e-91 306.5 20.2 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 KXL42345.1 - 1.4e-10 40.6 5.7 2e-10 40.1 5.7 1.2 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like HCV_env PF01539.17 KXL42345.1 - 0.00056 19.7 1.9 0.0011 18.7 1.9 1.5 1 0 0 1 1 1 1 Hepatitis C virus envelope glycoprotein E1 DUF5518 PF17647.1 KXL42345.1 - 0.014 15.5 7.4 0.014 15.5 7.4 2.9 2 1 1 3 3 3 0 Family of unknown function (DUF5518) EamA PF00892.20 KXL42345.1 - 0.02 15.1 27.5 0.43 10.8 12.3 2.3 2 0 0 2 2 2 0 EamA-like transporter family DUF3659 PF12396.8 KXL42346.1 - 9.4e-15 54.3 0.1 1.8e-14 53.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3659) SMK-1 PF04802.15 KXL42347.1 - 1.1e-70 237.4 1.5 2e-70 236.6 1.5 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 DUF3572 PF12096.8 KXL42347.1 - 0.0067 16.6 0.3 0.25 11.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3572) Bromo_TP_like PF17027.5 KXL42347.1 - 0.084 13.0 0.1 0.32 11.1 0.1 2.0 1 0 0 1 1 1 0 Histone-fold protein PBP1_TM PF14812.6 KXL42347.1 - 0.19 12.1 5.4 6.9 7.1 1.2 2.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Aldolase_II PF00596.21 KXL42348.1 - 2.6e-48 164.4 0.3 3.7e-48 163.9 0.3 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain WD40 PF00400.32 KXL42349.1 - 3.1e-26 91.1 14.9 1.7e-06 28.6 2.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL42349.1 - 8.4e-14 51.6 0.3 0.011 16.0 0.1 5.5 2 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXL42349.1 - 0.00018 21.4 0.1 0.03 14.2 0.1 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Carla_C4 PF01623.17 KXL42352.1 - 1.7 8.7 11.7 2.2 8.3 0.3 3.1 2 1 1 3 3 3 0 Carlavirus putative nucleic acid binding protein SET PF00856.28 KXL42353.1 - 9.1e-11 42.4 0.0 2.3e-10 41.1 0.0 1.7 1 1 0 1 1 1 1 SET domain TPR_14 PF13428.6 KXL42353.1 - 0.0035 18.0 1.3 6.7 7.8 0.3 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXL42353.1 - 1.3 9.6 11.9 15 6.2 0.3 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4201 PF13870.6 KXL42354.1 - 0.0051 16.6 8.2 0.0051 16.6 8.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) DUF730 PF05325.11 KXL42354.1 - 0.091 12.8 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF730) VPS28 PF03997.12 KXL42354.1 - 0.19 11.4 1.5 0.77 9.4 0.2 2.3 1 1 1 2 2 2 0 VPS28 protein Macoilin PF09726.9 KXL42354.1 - 3.2 6.2 12.6 0.047 12.3 3.2 2.1 2 0 0 2 2 2 0 Macoilin family GAS PF13851.6 KXL42354.1 - 4.8 6.5 8.5 4.6 6.5 3.6 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding adh_short PF00106.25 KXL42355.1 - 1.2e-29 103.1 0.2 1.9e-21 76.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXL42355.1 - 1.3e-22 80.5 0.1 1.6e-20 73.7 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL42355.1 - 0.00019 21.4 0.0 0.00029 20.8 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KXL42355.1 - 0.027 13.9 0.0 0.21 10.9 0.0 2.0 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Peripla_BP_6 PF13458.6 KXL42355.1 - 0.053 13.2 0.0 0.092 12.4 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein PH_9 PF15410.6 KXL42357.1 - 0.0044 17.4 0.0 0.0092 16.3 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain zf-H2C2_2 PF13465.6 KXL42359.1 - 0.0012 19.2 4.6 0.71 10.4 0.9 2.5 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KXL42359.1 - 0.047 14.2 12.9 1.1 9.9 0.2 3.4 2 1 1 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXL42359.1 - 2.8 9.0 5.8 35 5.6 0.1 3.4 3 1 0 3 3 3 0 C2H2-type zinc finger DHH PF01368.20 KXL42360.1 - 0.039 14.2 0.0 0.073 13.3 0.0 1.4 1 0 0 1 1 1 0 DHH family ArAE_2_N PF10337.9 KXL42361.1 - 1.6e-38 132.9 10.8 2.2e-32 112.7 1.3 4.1 3 2 1 4 4 4 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 KXL42361.1 - 2.4e-18 66.5 15.9 2.4e-18 66.5 15.9 3.1 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 KXL42361.1 - 8.8e-10 38.8 0.1 5.4e-09 36.2 0.0 2.3 2 2 0 2 2 2 1 Aromatic acid exporter family member 2 ALMT PF11744.8 KXL42361.1 - 5.8 5.6 15.6 10 4.8 12.8 2.5 2 1 0 2 2 2 0 Aluminium activated malate transporter HSP90 PF00183.18 KXL42362.1 - 3.8e-220 732.2 35.7 4.8e-220 731.8 35.7 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KXL42362.1 - 2.4e-15 57.0 0.1 4.4e-15 56.2 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KXL42362.1 - 1.1e-10 41.5 0.2 1.1e-10 41.5 0.2 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1676 PF07898.13 KXL42362.1 - 0.28 11.2 4.9 0.47 10.5 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Peptidase_S10 PF00450.22 KXL42362.1 - 0.33 10.3 0.0 0.33 10.3 0.0 2.3 3 0 0 3 3 3 0 Serine carboxypeptidase Cofac_haem_bdg PF04187.13 KXL42362.1 - 4.8 7.1 5.3 1.7 8.6 0.5 2.7 2 2 1 3 3 3 0 Haem-binding uptake, Tiki superfamily, ChaN DUF5631 PF18645.1 KXL42363.1 - 0.00068 20.0 0.6 0.0041 17.5 0.6 2.5 1 0 0 1 1 1 1 Family of unknown function (DUF5631) Alpha-L-AF_C PF06964.12 KXL42364.1 - 6.2e-16 59.0 0.0 1.6e-15 57.7 0.0 1.6 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain DUF1134 PF06577.12 KXL42365.1 - 0.09 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1134) CRAL_TRIO PF00650.20 KXL42365.1 - 0.097 12.4 0.0 0.35 10.6 0.0 1.8 2 0 0 2 2 2 0 CRAL/TRIO domain Peptidase_C50 PF03568.17 KXL42367.1 - 1.1e-140 469.3 0.6 2.3e-140 468.2 0.1 1.9 2 0 0 2 2 2 1 Peptidase family C50 TPR_12 PF13424.6 KXL42367.1 - 0.034 14.4 1.1 1.5 9.1 0.5 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXL42367.1 - 0.1 12.8 1.6 46 4.5 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat CCDC106 PF15794.5 KXL42367.1 - 1 9.0 4.9 1.4 8.6 0.1 2.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 PTCB-BRCT PF12738.7 KXL42368.1 - 0.0019 18.1 0.0 0.0064 16.4 0.0 1.8 2 0 0 2 2 2 1 twin BRCT domain MBF1 PF08523.10 KXL42369.1 - 0.11 13.0 3.2 0.16 12.4 2.9 1.5 1 1 0 1 1 1 0 Multiprotein bridging factor 1 DAHP_synth_2 PF01474.16 KXL42370.1 - 3.6e-207 688.1 0.0 4.1e-207 687.9 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Totivirus_coat PF05518.11 KXL42370.1 - 0.22 9.5 0.0 0.32 9.0 0.0 1.2 1 0 0 1 1 1 0 Totivirus coat protein Amidase PF01425.21 KXL42371.1 - 4.6e-64 217.0 0.0 1.1e-45 156.5 0.0 3.0 1 1 2 3 3 3 3 Amidase AMP-binding PF00501.28 KXL42372.1 - 1.2e-65 221.8 0.0 1.4e-65 221.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXL42372.1 - 3.9e-09 37.4 0.0 8.2e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WD40 PF00400.32 KXL42373.1 - 2.6e-18 66.0 9.2 0.00082 20.1 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL42373.1 - 1.2e-15 57.6 0.0 7.5e-05 23.0 0.0 4.9 2 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXL42373.1 - 5.1e-05 23.2 0.2 0.037 13.9 0.0 3.3 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KXL42373.1 - 0.017 15.0 6.0 1.7 8.7 0.1 4.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Cupin_2 PF07883.11 KXL42374.1 - 1.5e-12 47.0 0.3 2.1e-12 46.6 0.3 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KXL42374.1 - 7.2e-05 22.4 0.0 8.8e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 KXL42374.1 - 0.0002 21.0 0.0 0.0003 20.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) AraC_binding PF02311.19 KXL42374.1 - 0.037 13.9 0.0 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain HutD PF05962.11 KXL42374.1 - 0.058 13.4 0.0 0.066 13.2 0.0 1.1 1 0 0 1 1 1 0 HutD Cupin_6 PF12852.7 KXL42374.1 - 0.1 12.3 0.0 0.13 12.0 0.0 1.3 1 1 0 1 1 1 0 Cupin GPI PF06560.11 KXL42374.1 - 0.13 11.5 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Peptidase_C14 PF00656.22 KXL42374.1 - 0.17 11.8 0.0 0.2 11.6 0.0 1.1 1 0 0 1 1 1 0 Caspase domain DUF5127 PF17168.4 KXL42375.1 - 1.2e-72 244.5 8.6 5.7e-42 144.0 3.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KXL42375.1 - 3e-72 241.9 0.2 5.3e-72 241.1 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KXL42375.1 - 7.4e-65 218.4 0.6 7.4e-65 218.4 0.6 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KXL42375.1 - 4e-08 32.7 0.0 1.3e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Pyr_redox_2 PF07992.14 KXL42377.1 - 4.1e-10 39.4 0.0 4.6e-09 35.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXL42377.1 - 6.2e-10 38.1 0.0 1.3e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXL42377.1 - 7.8e-10 38.8 0.0 1.9e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXL42377.1 - 4.1e-09 36.1 0.0 5.9e-06 25.8 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXL42377.1 - 2.3e-08 33.6 0.0 0.00019 20.7 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KXL42377.1 - 6.6e-08 32.5 0.0 0.4 10.2 0.0 3.2 2 1 0 3 3 3 3 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXL42377.1 - 0.0025 17.8 0.3 0.52 10.3 0.0 3.4 2 2 0 2 2 2 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 KXL42377.1 - 0.044 13.8 0.0 18 5.3 0.0 3.2 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Amino_oxidase PF01593.24 KXL42377.1 - 0.047 13.0 0.0 4.7 6.4 0.0 2.6 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase DUF2335 PF10097.9 KXL42377.1 - 0.14 12.2 0.1 0.33 10.9 0.1 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) DNA_binding_1 PF01035.20 KXL42379.1 - 3.9e-21 75.0 0.0 4.6e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain HTH_28 PF13518.6 KXL42379.1 - 0.016 15.3 0.0 0.024 14.8 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 KXL42379.1 - 0.03 14.0 0.1 0.05 13.3 0.1 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_23 PF13384.6 KXL42379.1 - 0.042 13.6 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Syntaxin PF00804.25 KXL42381.1 - 2e-18 66.8 10.7 8.7e-18 64.7 10.7 1.9 1 1 0 1 1 1 1 Syntaxin SNARE PF05739.19 KXL42381.1 - 9.4e-13 48.0 1.1 9.4e-13 48.0 1.1 2.2 2 0 0 2 2 2 1 SNARE domain TMCO5 PF14992.6 KXL42381.1 - 0.0085 15.7 2.0 0.0085 15.7 2.0 1.9 2 0 0 2 2 2 1 TMCO5 family RIFIN PF02009.16 KXL42381.1 - 0.014 15.3 4.7 0.021 14.7 4.7 1.3 1 0 0 1 1 1 0 Rifin Spectrin PF00435.21 KXL42381.1 - 0.03 14.8 8.5 1.2 9.6 0.0 3.2 2 1 1 3 3 3 0 Spectrin repeat SKA2 PF16740.5 KXL42381.1 - 0.095 12.5 9.8 0.37 10.6 3.9 3.0 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 AAA_23 PF13476.6 KXL42381.1 - 0.13 12.8 9.5 0.19 12.2 9.5 1.3 1 0 0 1 1 1 0 AAA domain LZ_Tnp_IS481 PF13011.6 KXL42381.1 - 0.18 12.3 0.2 0.18 12.3 0.2 1.8 2 0 0 2 2 1 0 leucine-zipper of insertion element IS481 DUF3533 PF12051.8 KXL42381.1 - 0.32 9.9 1.8 0.47 9.3 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) BLOC1_2 PF10046.9 KXL42381.1 - 0.37 11.1 6.0 0.094 13.0 1.4 2.3 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4094 PF13334.6 KXL42381.1 - 1.5 9.3 5.0 1.3 9.5 0.8 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) TMPIT PF07851.13 KXL42381.1 - 2.8 7.1 5.7 14 4.8 0.0 2.1 1 1 1 2 2 2 0 TMPIT-like protein NPV_P10 PF05531.12 KXL42381.1 - 3.7 8.1 7.2 21 5.6 2.8 2.8 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein FAM76 PF16046.5 KXL42381.1 - 7.4 5.8 9.0 17 4.7 9.0 1.5 1 1 1 2 2 2 0 FAM76 protein DASH_Spc19 PF08287.11 KXL42381.1 - 9.6 6.1 16.4 1.4 8.8 8.8 2.5 2 1 1 3 3 3 0 Spc19 Translin PF01997.16 KXL42382.1 - 8.6e-64 215.3 0.1 1e-63 215.0 0.1 1.1 1 0 0 1 1 1 1 Translin family SLX9 PF15341.6 KXL42382.1 - 0.19 12.1 0.1 0.19 12.1 0.1 1.9 3 0 0 3 3 3 0 Ribosome biogenesis protein SLX9 Maf PF02545.14 KXL42383.1 - 9.4e-51 172.0 0.0 1.7e-50 171.2 0.0 1.4 1 0 0 1 1 1 1 Maf-like protein V-ATPase_G PF03179.15 KXL42383.1 - 7.5e-32 110.0 14.7 1.2e-31 109.3 14.7 1.3 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Borrelia_P83 PF05262.11 KXL42383.1 - 0.2 10.1 11.1 0.27 9.7 11.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein KfrA_N PF11740.8 KXL42383.1 - 0.41 11.3 7.8 1.6 9.4 7.8 2.0 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term ECM11 PF15463.6 KXL42383.1 - 0.88 10.2 9.1 2.4 8.7 9.1 1.8 1 1 0 1 1 1 0 Extracellular mutant protein 11 DUF3552 PF12072.8 KXL42383.1 - 3.5 7.0 19.0 3.7 6.9 16.9 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3552) RRF PF01765.19 KXL42383.1 - 6.9 6.6 13.3 15 5.5 13.3 1.6 1 1 0 1 1 1 0 Ribosome recycling factor Acyl-CoA_dh_1 PF00441.24 KXL42384.1 - 1.1e-38 132.8 3.5 2.4e-38 131.7 3.5 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXL42384.1 - 1.4e-30 106.2 0.7 2.2e-30 105.6 0.1 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KXL42384.1 - 3.1e-24 85.0 0.0 7.7e-24 83.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXL42384.1 - 3.4e-17 63.0 1.3 5.9e-17 62.2 1.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KXL42384.1 - 0.00043 20.0 0.0 0.0011 18.7 0.0 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Glyco_trans_4_4 PF13579.6 KXL42385.1 - 0.27 11.7 1.4 9 6.7 0.0 2.9 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain SH3_9 PF14604.6 KXL42387.1 - 1.9e-13 50.0 0.0 3.4e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXL42387.1 - 5.4e-12 45.1 0.0 9.8e-12 44.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 KXL42387.1 - 1.6e-10 41.4 0.0 3.2e-09 37.2 0.0 2.5 1 1 0 1 1 1 1 PH domain SAM_2 PF07647.17 KXL42387.1 - 3.8e-09 36.5 0.0 7.1e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 KXL42387.1 - 0.00023 20.8 0.0 0.00058 19.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.30 KXL42387.1 - 0.0035 17.7 0.0 0.0077 16.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_8 PF15409.6 KXL42387.1 - 0.0044 17.3 0.0 0.36 11.1 0.0 3.0 3 0 0 3 3 3 1 Pleckstrin homology domain PH_11 PF15413.6 KXL42387.1 - 0.0054 17.1 0.6 0.024 15.0 0.0 2.4 3 0 0 3 3 3 1 Pleckstrin homology domain zf-MIZ PF02891.20 KXL42388.1 - 4.4e-08 32.7 1.3 8.3e-08 31.9 1.3 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger MFS_1 PF07690.16 KXL42389.1 - 2.2e-45 155.1 47.1 3.7e-40 137.9 27.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SieB PF14163.6 KXL42389.1 - 0.095 12.2 0.8 0.54 9.8 0.1 2.5 3 0 0 3 3 3 0 Super-infection exclusion protein B RPAP1_N PF08621.10 KXL42389.1 - 0.17 11.7 1.8 0.49 10.2 1.8 1.8 1 0 0 1 1 1 0 RPAP1-like, N-terminal DUF1129 PF06570.11 KXL42389.1 - 0.89 9.0 3.9 1.8 8.0 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) FAD_binding_4 PF01565.23 KXL42391.1 - 6.7e-13 48.6 2.2 2.4e-11 43.6 1.1 2.3 2 0 0 2 2 2 2 FAD binding domain Lactonase PF10282.9 KXL42392.1 - 2.7e-81 273.5 0.0 3e-81 273.4 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DNA_pol_B PF00136.21 KXL42393.1 - 3.1e-104 349.2 0.0 4.4e-104 348.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KXL42393.1 - 2e-26 92.9 0.1 1.1e-16 61.0 0.0 2.6 2 1 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KXL42393.1 - 8.8e-17 61.3 4.2 8.8e-17 61.3 4.2 2.3 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta Glyco_hydro_31 PF01055.26 KXL42394.1 - 3.8e-155 517.4 6.8 5.1e-155 517.0 6.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KXL42394.1 - 1.1e-37 128.7 0.2 2.3e-37 127.7 0.2 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase CBM_20 PF00686.19 KXL42394.1 - 2.5e-18 65.8 0.8 8.3e-18 64.1 0.8 1.9 1 0 0 1 1 1 1 Starch binding domain Gal_mutarotas_2 PF13802.6 KXL42394.1 - 6.2e-12 45.7 2.6 1.6e-11 44.3 1.3 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like p450 PF00067.22 KXL42395.1 - 3.8e-39 134.7 0.0 1.5e-38 132.8 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 WD40 PF00400.32 KXL42398.1 - 3.6e-07 30.8 4.5 1.9 9.5 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL42398.1 - 0.1 12.9 0.0 45 4.5 0.0 3.4 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Chitin_synth_2 PF03142.15 KXL42399.1 - 5.9e-281 932.6 0.0 9.6e-281 932.0 0.0 1.3 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KXL42399.1 - 7.1e-11 42.4 1.9 2.2e-10 40.8 1.2 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXL42399.1 - 5.3e-09 36.3 0.1 4.4e-08 33.3 0.0 2.4 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KXL42399.1 - 0.0076 15.8 0.0 0.15 11.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KXL42399.1 - 0.22 11.3 0.0 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 MBOAT_2 PF13813.6 KXL42400.1 - 0.078 13.3 0.2 0.11 12.8 0.2 1.2 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family Sel1 PF08238.12 KXL42401.1 - 5.4e-38 128.6 33.4 2.5e-05 24.8 0.0 7.4 7 0 0 7 7 7 7 Sel1 repeat DUF3477 PF11963.8 KXL42401.1 - 0.2 10.8 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3477) TPR_6 PF13174.6 KXL42401.1 - 0.21 12.3 4.7 9.9 7.0 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Glyco_hydro_18 PF00704.28 KXL42402.1 - 6.2e-24 85.3 2.0 7.8e-23 81.7 2.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Methyltransf_25 PF13649.6 KXL42404.1 - 3.1e-17 63.0 0.0 2.2e-16 60.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL42404.1 - 1.3e-13 51.4 0.0 6.4e-13 49.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL42404.1 - 3.8e-13 49.5 0.0 5.9e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL42404.1 - 3.8e-12 46.8 0.0 6.2e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXL42404.1 - 3e-10 39.9 0.0 4.3e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KXL42404.1 - 4.2e-08 32.8 0.0 5.8e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase RrnaAD PF00398.20 KXL42404.1 - 2.8e-06 26.6 0.0 4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.6 KXL42404.1 - 6.1e-06 26.2 0.0 8e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KXL42404.1 - 1.9e-05 24.7 0.0 3.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXL42404.1 - 2.8e-05 23.6 0.0 3.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KXL42404.1 - 3.7e-05 23.3 0.0 6.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.19 KXL42404.1 - 4.4e-05 23.3 0.0 8.1e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 KXL42404.1 - 7.6e-05 21.8 0.0 0.00011 21.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) DOT1 PF08123.13 KXL42404.1 - 0.00049 19.7 0.0 0.0008 19.0 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 PrmA PF06325.13 KXL42404.1 - 0.00096 18.6 0.0 0.0012 18.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 KXL42404.1 - 0.0013 18.7 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 KXL42404.1 - 0.0041 16.8 0.0 0.0056 16.3 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F MetW PF07021.12 KXL42404.1 - 0.022 14.3 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.15 KXL42404.1 - 0.024 14.5 0.0 1.9 8.3 0.0 2.3 2 0 0 2 2 2 0 Hypothetical methyltransferase TPMT PF05724.11 KXL42404.1 - 0.025 14.2 0.0 0.067 12.8 0.0 1.7 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Spermine_synth PF01564.17 KXL42404.1 - 0.027 13.9 0.0 0.091 12.2 0.0 1.8 1 1 0 1 1 1 0 Spermine/spermidine synthase domain NodS PF05401.11 KXL42404.1 - 0.034 13.8 0.0 0.044 13.4 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) DREV PF05219.12 KXL42404.1 - 0.079 12.0 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 DREV methyltransferase Dpy-30 PF05186.13 KXL42406.1 - 5.1e-11 42.1 0.1 7.3e-11 41.6 0.1 1.3 1 0 0 1 1 1 1 Dpy-30 motif DUF3933 PF13069.6 KXL42406.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3933) Peroxin-13_N PF04088.13 KXL42407.1 - 3.7e-52 176.4 0.3 6.3e-52 175.7 0.3 1.4 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 KXL42407.1 - 8.4e-09 35.0 0.0 1.7e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXL42407.1 - 3.3e-07 29.8 0.1 1.5e-06 27.7 0.1 2.0 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXL42407.1 - 7.4e-05 22.5 0.1 0.0002 21.1 0.1 1.8 1 1 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.6 KXL42407.1 - 0.14 12.6 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 Helically-extended SH3 domain 7tm_2 PF00002.24 KXL42408.1 - 0.00064 19.1 10.5 0.00064 19.1 3.0 2.3 2 0 0 2 2 2 2 7 transmembrane receptor (Secretin family) PhaG_MnhG_YufB PF03334.14 KXL42408.1 - 0.086 13.1 0.3 0.086 13.1 0.3 3.0 3 1 0 3 3 3 0 Na+/H+ antiporter subunit DUF202 PF02656.15 KXL42409.1 - 7.3e-17 61.6 0.5 1.7e-16 60.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) BCDHK_Adom3 PF10436.9 KXL42410.1 - 2.7e-45 154.1 0.0 3.6e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KXL42410.1 - 1.7e-08 35.0 0.0 3.7e-07 30.6 0.0 2.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Whi5 PF08528.11 KXL42411.1 - 2.7e-10 39.7 0.0 5.5e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Whi5 like RIBIOP_C PF04950.12 KXL42413.1 - 5.4e-95 318.2 0.0 1.1e-94 317.1 0.0 1.5 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KXL42413.1 - 2.8e-27 94.6 0.0 1e-26 92.8 0.0 2.1 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 KXL42413.1 - 4.1e-05 23.9 0.0 9.8e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXL42413.1 - 4.4e-05 23.9 0.0 0.00013 22.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 KXL42413.1 - 6e-05 22.7 0.0 0.009 15.6 0.0 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KXL42413.1 - 0.00036 20.6 0.1 0.0011 19.0 0.1 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KXL42413.1 - 0.00046 20.4 0.0 0.00046 20.4 0.0 2.1 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.27 KXL42413.1 - 0.0017 18.8 0.4 0.0094 16.5 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA PF00004.29 KXL42413.1 - 0.0027 18.1 0.0 0.0058 17.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KXL42413.1 - 0.0033 16.6 0.0 0.0084 15.3 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_19 PF13245.6 KXL42413.1 - 0.0084 16.5 0.1 0.02 15.2 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXL42413.1 - 0.019 15.5 0.3 0.019 15.5 0.3 3.1 3 0 0 3 3 2 0 AAA domain cobW PF02492.19 KXL42413.1 - 0.02 14.5 0.1 0.044 13.4 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KXL42413.1 - 0.023 14.4 0.1 0.053 13.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXL42413.1 - 0.032 14.1 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 KXL42413.1 - 0.034 14.1 0.0 0.43 10.6 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE KAP_NTPase PF07693.14 KXL42413.1 - 0.034 13.4 0.0 0.075 12.3 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain RNA_helicase PF00910.22 KXL42413.1 - 0.075 13.4 0.0 0.19 12.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Roc PF08477.13 KXL42413.1 - 0.077 13.2 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KXL42413.1 - 0.086 12.7 0.0 0.26 11.2 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase MobB PF03205.14 KXL42413.1 - 0.089 12.7 0.1 0.46 10.4 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 KXL42413.1 - 0.091 12.7 0.6 0.18 11.7 0.6 1.5 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.14 KXL42413.1 - 0.1 12.6 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MeaB PF03308.16 KXL42413.1 - 0.11 11.5 0.0 0.11 11.5 0.0 1.7 2 0 0 2 2 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 KXL42413.1 - 0.13 11.8 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 KXL42413.1 - 0.13 12.0 0.0 0.89 9.3 0.0 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 KXL42413.1 - 0.17 11.6 0.1 0.34 10.7 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF5353 PF17304.2 KXL42414.1 - 4.7e-34 115.9 4.8 6.3e-34 115.5 4.8 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5353) T3SSipB PF16535.5 KXL42414.1 - 0.033 14.7 0.7 0.047 14.2 0.7 1.2 1 0 0 1 1 1 0 Type III cell invasion protein SipB DUF883 PF05957.13 KXL42414.1 - 0.042 14.5 0.9 0.042 14.5 0.9 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Peptidase_C12 PF01088.21 KXL42415.1 - 2.4e-62 210.4 0.0 3.1e-62 210.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KXL42415.1 - 2.2e-11 43.5 1.1 5.8e-11 42.1 1.1 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases TPP_enzyme_N PF02776.18 KXL42416.1 - 1.4e-40 138.7 0.1 7.7e-39 133.0 0.1 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KXL42416.1 - 4.1e-20 72.1 0.2 7.5e-20 71.3 0.2 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXL42416.1 - 7.2e-10 38.7 0.0 3.5e-09 36.5 0.0 2.2 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain ORF_12_N PF18042.1 KXL42416.1 - 0.082 13.3 0.1 15 6.1 0.0 2.7 2 0 0 2 2 2 0 ORF 12 gene product N-terminal Lactamase_B PF00753.27 KXL42417.1 - 2.8e-07 30.7 5.3 2.8e-07 30.7 5.3 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXL42417.1 - 7.1e-06 25.7 0.0 1.5e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXL42417.1 - 0.09 12.7 0.1 0.19 11.6 0.1 1.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain CMD PF02627.20 KXL42418.1 - 1.6e-20 72.9 0.1 2.4e-20 72.4 0.1 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family DSPc PF00782.20 KXL42419.1 - 2.3e-09 37.2 0.0 3.8e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXL42419.1 - 0.00025 20.7 0.0 0.0004 20.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KXL42419.1 - 0.098 12.6 0.0 0.25 11.3 0.0 1.6 2 0 0 2 2 2 0 Tyrosine phosphatase family AMP-binding PF00501.28 KXL42420.1 - 1.6e-69 234.6 0.0 1.9e-69 234.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXL42420.1 - 1.2e-19 71.0 0.5 2.1e-19 70.2 0.5 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GST_N_3 PF13417.6 KXL42421.1 - 2.3e-09 37.5 0.1 2.6e-08 34.1 0.1 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXL42421.1 - 2.3e-05 24.6 0.1 0.00027 21.2 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXL42421.1 - 0.00017 21.5 0.0 0.0003 20.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXL42421.1 - 0.051 13.8 0.0 0.09 13.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXL42421.1 - 0.065 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RNA_pol_Rpb1_5 PF04998.17 KXL42422.1 - 1.8e-89 299.7 0.3 4.2e-89 298.5 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KXL42422.1 - 2.2e-68 229.7 0.0 5.2e-68 228.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KXL42422.1 - 2.3e-29 102.4 0.0 9.5e-29 100.4 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 KXL42422.1 - 5.1e-28 98.3 4.7 6.2e-27 94.7 4.5 2.9 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 KXL42422.1 - 6.6e-20 71.1 0.0 3.9e-19 68.6 0.0 2.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Epimerase PF01370.21 KXL42423.1 - 2.5e-14 53.3 0.0 3.4e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXL42423.1 - 8.4e-10 38.8 0.1 1.8e-09 37.7 0.1 1.7 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXL42423.1 - 3.6e-07 30.0 0.1 7.1e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 KXL42423.1 - 3e-06 26.4 0.0 5.6e-06 25.6 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KXL42423.1 - 2.7e-05 23.5 0.0 3.9e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KXL42423.1 - 3.3e-05 23.4 0.0 9.2e-05 22.0 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KXL42423.1 - 0.00024 20.6 0.2 0.082 12.4 0.1 2.6 2 1 0 2 2 2 2 short chain dehydrogenase NAD_binding_4 PF07993.12 KXL42423.1 - 0.002 17.4 0.0 0.025 13.7 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein RF3_C PF16658.5 KXL42423.1 - 0.084 12.7 0.0 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 Class II release factor RF3, C-terminal domain KR PF08659.10 KXL42423.1 - 0.086 12.8 0.0 0.68 9.8 0.0 2.0 1 1 0 1 1 1 0 KR domain Patatin PF01734.22 KXL42424.1 - 4e-19 69.6 0.0 1e-10 42.1 0.0 2.4 2 0 0 2 2 2 2 Patatin-like phospholipase zf-C2H2 PF00096.26 KXL42426.1 - 2.6e-05 24.4 11.9 0.0094 16.4 1.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXL42426.1 - 0.00025 21.3 6.4 0.00028 21.2 3.8 2.4 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXL42426.1 - 0.0019 18.9 11.5 0.074 13.9 2.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger TylF PF05711.11 KXL42426.1 - 0.27 10.5 0.0 0.43 9.8 0.0 1.3 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) HTH_Tnp_ISL3 PF13542.6 KXL42429.1 - 0.00032 20.1 0.1 0.00041 19.7 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 KXL42429.1 - 0.00098 18.9 0.1 0.0013 18.5 0.1 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 KXL42429.1 - 0.0011 18.9 0.1 0.0013 18.7 0.1 1.4 1 1 0 1 1 1 1 Winged helix-turn helix HTH_1 PF00126.27 KXL42429.1 - 0.0017 18.3 0.0 0.0027 17.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family SpoIIID PF12116.8 KXL42429.1 - 0.004 17.2 0.1 0.0043 17.1 0.1 1.2 1 0 0 1 1 1 1 Stage III sporulation protein D HTH_7 PF02796.15 KXL42429.1 - 0.0075 16.3 0.3 0.013 15.6 0.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_psq PF05225.16 KXL42429.1 - 0.014 15.2 0.1 0.019 14.7 0.1 1.3 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_6 PF01418.17 KXL42429.1 - 0.06 13.3 0.4 0.12 12.4 0.2 1.6 1 1 1 2 2 2 0 Helix-turn-helix domain, rpiR family HTH_28 PF13518.6 KXL42429.1 - 0.089 12.9 0.1 0.13 12.4 0.1 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_30 PF13556.6 KXL42429.1 - 0.13 12.1 0.3 0.18 11.6 0.3 1.3 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain TFIIA PF03153.13 KXL42437.1 - 2.9 7.8 14.9 3.2 7.6 14.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GST_N_2 PF13409.6 KXL42438.1 - 8e-15 54.9 0.0 1.7e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXL42438.1 - 2.3e-08 34.0 0.0 6.2e-08 32.6 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXL42438.1 - 0.0017 18.5 0.0 0.0045 17.1 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KXL42438.1 - 0.078 13.6 0.0 0.19 12.3 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain HTH_psq PF05225.16 KXL42439.1 - 0.0033 17.1 0.2 0.0054 16.4 0.2 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_7 PF02796.15 KXL42439.1 - 0.079 13.0 0.3 0.13 12.3 0.3 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Methyltransf_16 PF10294.9 KXL42440.1 - 5.7e-16 58.7 0.0 2.7e-15 56.5 0.0 1.9 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KXL42440.1 - 0.15 12.8 0.0 0.3 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain VPS28 PF03997.12 KXL42441.1 - 9.1e-59 198.3 0.0 1.1e-58 198.0 0.0 1.1 1 0 0 1 1 1 1 VPS28 protein Vps23_core PF09454.10 KXL42441.1 - 0.087 12.8 0.3 0.18 11.8 0.3 1.5 1 0 0 1 1 1 0 Vps23 core domain Noc2 PF03715.13 KXL42442.1 - 1.9e-102 342.5 0.0 2.8e-102 342.0 0.0 1.2 1 0 0 1 1 1 1 Noc2p family EOS1 PF12326.8 KXL42443.1 - 0.011 15.7 0.1 0.011 15.7 0.1 1.1 1 0 0 1 1 1 0 N-glycosylation protein eIF-3_zeta PF05091.12 KXL42443.1 - 0.016 14.2 10.5 0.02 13.9 10.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RR_TM4-6 PF06459.12 KXL42443.1 - 0.18 11.6 9.6 0.24 11.2 9.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SpoIIP PF07454.11 KXL42443.1 - 0.72 9.3 12.4 0.95 8.9 12.4 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CPSF100_C PF13299.6 KXL42443.1 - 0.74 10.0 7.3 1 9.5 7.3 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Connexin PF00029.19 KXL42443.1 - 1.1 8.9 8.0 1.4 8.6 8.0 1.1 1 0 0 1 1 1 0 Connexin EIIBC-GUT_N PF03612.14 KXL42443.1 - 1.6 8.4 9.5 2.1 8.1 9.5 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus EPL1 PF10513.9 KXL42443.1 - 2 8.8 14.8 3.9 7.8 14.8 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like SLC12 PF03522.15 KXL42443.1 - 2.2 7.2 11.1 2.7 6.9 11.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Serinc PF03348.15 KXL42443.1 - 2.3 7.0 5.1 2.8 6.8 5.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2828 PF11443.8 KXL42443.1 - 2.6 6.0 10.4 3.3 5.7 10.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF4407 PF14362.6 KXL42443.1 - 3.5 6.9 10.8 4.3 6.6 10.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CobT PF06213.12 KXL42443.1 - 3.6 6.9 19.0 5.1 6.4 19.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT GREB1 PF15782.5 KXL42443.1 - 3.6 4.6 14.8 4.3 4.3 14.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4820 PF16091.5 KXL42443.1 - 4.1 6.7 9.1 5.6 6.3 9.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Presenilin PF01080.17 KXL42443.1 - 4.9 5.8 17.7 6.5 5.4 17.7 1.1 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.6 KXL42443.1 - 5.2 7.0 10.7 7.6 6.5 10.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A V_ATPase_I PF01496.19 KXL42443.1 - 5.4 4.8 13.7 6.7 4.5 13.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Baculo_PP31 PF05311.11 KXL42443.1 - 7.5 5.9 12.2 9.8 5.6 12.2 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) TERB2 PF15101.6 KXL42443.1 - 9.3 6.2 18.9 14 5.7 18.9 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 bZIP_1 PF00170.21 KXL42444.1 - 8.9e-05 22.5 12.6 0.001 19.1 6.6 2.2 1 1 1 2 2 2 2 bZIP transcription factor Tmemb_cc2 PF10267.9 KXL42444.1 - 0.0031 16.7 3.7 0.0038 16.4 3.7 1.0 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein TMF_DNA_bd PF12329.8 KXL42444.1 - 0.0092 16.0 6.9 0.0095 15.9 6.0 1.5 1 1 0 1 1 1 1 TATA element modulatory factor 1 DNA binding YabA PF06156.13 KXL42444.1 - 0.023 15.3 2.1 0.034 14.8 2.1 1.3 1 0 0 1 1 1 0 Initiation control protein YabA bZIP_2 PF07716.15 KXL42444.1 - 0.059 13.5 16.6 0.64 10.1 7.3 2.3 1 1 1 2 2 2 0 Basic region leucine zipper UPF0242 PF06785.11 KXL42444.1 - 0.1 12.7 4.8 0.13 12.4 4.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TSC22 PF01166.18 KXL42444.1 - 0.12 12.7 4.1 0.33 11.3 0.8 2.2 1 1 1 2 2 2 0 TSC-22/dip/bun family Tox-ODYAM1 PF15642.6 KXL42444.1 - 0.14 11.1 2.1 0.16 10.9 2.1 1.0 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus HAUS6_N PF14661.6 KXL42444.1 - 0.2 11.2 8.7 0.23 11.0 8.7 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus ABC_tran_Xtn PF12848.7 KXL42444.1 - 2.7 8.1 9.2 4.3 7.4 9.2 1.3 1 0 0 1 1 1 0 ABC transporter DUF2992 PF11208.8 KXL42444.1 - 6 7.1 10.8 5.7 7.2 10.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2992) K_channel_TID PF07941.11 KXL42445.1 - 0.23 12.0 5.4 0.067 13.7 2.5 1.6 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain p450 PF00067.22 KXL42446.1 - 1.2e-23 83.6 0.0 1.7e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 KXL42447.1 - 4.5e-48 163.7 0.0 7.2e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KXL42447.1 - 2.4e-28 99.2 0.0 4.1e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KXL42447.1 - 1.1e-16 61.4 0.0 3.1e-16 60.0 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Nucleopor_Nup85 PF07575.13 KXL42447.1 - 0.013 14.1 0.0 0.036 12.6 0.0 1.7 2 0 0 2 2 2 0 Nup85 Nucleoporin Fungal_trans_2 PF11951.8 KXL42448.1 - 0.00015 20.7 0.0 0.00023 20.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain OTT_1508_deam PF14441.6 KXL42448.1 - 0.24 11.4 2.9 0.52 10.4 1.4 2.3 3 0 0 3 3 3 0 OTT_1508-like deaminase Hid1 PF12722.7 KXL42451.1 - 9.2e-205 682.3 0.0 1.3e-204 681.8 0.0 1.2 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KXL42451.1 - 1.5e-78 264.8 0.0 1.8e-78 264.6 0.0 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Menin PF05053.13 KXL42451.1 - 0.16 10.3 0.2 10 4.3 0.1 2.2 2 0 0 2 2 2 0 Menin p450 PF00067.22 KXL42452.1 - 2.8e-36 125.3 0.0 3.1e-36 125.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pho88 PF10032.9 KXL42453.1 - 8.9e-83 276.0 0.6 9.9e-83 275.9 0.6 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) HATPase_c PF02518.26 KXL42454.1 - 9e-24 84.1 0.1 3.1e-23 82.4 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXL42454.1 - 5.1e-15 55.6 0.0 2.4e-14 53.5 0.0 2.2 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KXL42454.1 - 1.3e-14 53.9 0.1 5.6e-13 48.7 0.0 3.2 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 KXL42454.1 - 0.017 15.0 0.0 0.049 13.5 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FUN14 PF04930.15 KXL42455.1 - 3.6e-08 33.7 1.1 7.6e-07 29.5 1.5 2.2 2 0 0 2 2 2 1 FUN14 family MOSC PF03473.17 KXL42456.1 - 2.8e-22 79.1 0.0 4.8e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KXL42456.1 - 9.1e-17 61.0 0.0 1.6e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Cuticle_1 PF08140.11 KXL42456.1 - 0.039 14.0 0.1 0.083 12.9 0.0 1.6 2 0 0 2 2 2 0 Crustacean cuticle protein repeat Fungal_trans_2 PF11951.8 KXL42457.1 - 8.4e-11 41.3 0.1 1.6e-10 40.4 0.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL42457.1 - 6.6e-10 38.9 14.9 1.4e-09 37.9 14.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugarporin_N PF11471.8 KXL42458.1 - 0.17 11.9 10.6 0.29 11.1 2.7 3.4 2 1 1 3 3 3 0 Maltoporin periplasmic N-terminal extension Pept_tRNA_hydro PF01195.19 KXL42459.1 - 2.2e-38 131.9 0.0 2.8e-38 131.5 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PAN_4 PF14295.6 KXL42460.1 - 5.4e-33 112.7 10.8 1.6e-06 27.9 0.1 5.6 5 0 0 5 5 5 5 PAN domain PAN_2 PF08276.11 KXL42460.1 - 4.3e-05 23.6 13.5 0.23 11.6 0.1 5.4 5 0 0 5 5 5 2 PAN-like domain PAN_3 PF08277.12 KXL42460.1 - 0.16 11.8 11.9 3.6 7.5 0.1 4.9 5 0 0 5 5 5 0 PAN-like domain MANEC PF07502.14 KXL42460.1 - 0.38 11.1 9.4 3.9 7.8 0.1 4.4 5 0 0 5 5 5 0 MANEC domain Plasmodium_Vir PF05795.11 KXL42460.1 - 0.54 9.6 11.3 0.4 10.1 9.5 1.7 2 0 0 2 2 2 0 Plasmodium vivax Vir protein zf-C2HC5 PF06221.13 KXL42461.1 - 5.6e-22 77.5 6.2 8.8e-22 76.9 6.2 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Zn_clus PF00172.18 KXL42462.1 - 1.3e-07 31.7 7.6 1.8e-07 31.1 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ASL_C PF08328.11 KXL42462.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal DUF2461 PF09365.10 KXL42465.1 - 3.6e-78 262.3 0.0 5.5e-78 261.7 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) NUDIX_2 PF13869.6 KXL42465.1 - 0.088 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Nucleotide hydrolase TYW3 PF02676.14 KXL42466.1 - 5.3e-65 218.8 0.0 6.5e-65 218.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 Peptidase_A22B PF04258.13 KXL42467.1 - 5.3e-63 213.2 1.6 4.1e-62 210.3 1.6 2.2 1 1 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 KXL42467.1 - 9.2e-08 31.9 1.5 9.2e-08 31.9 1.5 2.1 2 0 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease Presenilin PF01080.17 KXL42467.1 - 0.031 13.1 0.3 0.031 13.1 0.3 3.4 5 0 0 5 5 5 0 Presenilin FAD_binding_7 PF03441.14 KXL42468.1 - 2.3e-45 154.6 0.1 4e-45 153.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KXL42468.1 - 7.3e-17 61.9 0.0 1.3e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase SRP-alpha_N PF04086.13 KXL42469.1 - 1.8e-59 202.1 0.0 2.3e-59 201.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 KXL42469.1 - 3.9e-43 147.4 2.2 4.2e-43 147.3 0.2 2.1 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain MeaB PF03308.16 KXL42469.1 - 1.5e-06 27.4 0.4 4e-06 26.0 0.1 1.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54_N PF02881.19 KXL42469.1 - 2e-06 27.9 0.0 4.1e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.6 KXL42469.1 - 0.0023 17.7 0.0 0.0023 17.7 0.0 2.2 3 0 0 3 3 3 1 AAA domain AAA_31 PF13614.6 KXL42469.1 - 0.0025 17.7 0.0 0.0082 16.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KXL42469.1 - 0.0077 15.5 0.0 0.017 14.4 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin CbiA PF01656.23 KXL42469.1 - 0.014 15.5 0.2 0.075 13.1 0.0 2.2 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 KXL42469.1 - 0.055 13.4 0.6 0.97 9.3 0.1 3.1 3 1 0 3 3 3 0 NTPase cobW PF02492.19 KXL42469.1 - 0.074 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ArsA_ATPase PF02374.15 KXL42469.1 - 0.083 12.1 0.1 0.68 9.1 0.0 2.0 2 0 0 2 2 2 0 Anion-transporting ATPase AAA_16 PF13191.6 KXL42469.1 - 0.12 12.7 0.0 0.12 12.7 0.0 2.6 2 1 1 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 KXL42469.1 - 0.13 12.5 0.1 0.6 10.4 0.0 2.2 3 0 0 3 3 3 0 AAA domain Hamartin PF04388.12 KXL42469.1 - 0.81 8.3 1.6 1.1 7.9 1.6 1.1 1 0 0 1 1 1 0 Hamartin protein ApbA PF02558.16 KXL42470.1 - 1.2e-30 106.1 0.1 1.7e-30 105.7 0.1 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KXL42470.1 - 1.5e-29 102.8 0.0 4.9e-29 101.1 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal PglD_N PF17836.1 KXL42470.1 - 0.14 12.8 0.1 0.27 11.9 0.1 1.5 1 0 0 1 1 1 0 PglD N-terminal domain DUF2089 PF09862.9 KXL42471.1 - 0.019 15.0 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) HTH_30 PF13556.6 KXL42471.1 - 0.043 13.6 0.1 0.63 9.9 0.1 2.1 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain NAD_binding_4 PF07993.12 KXL42472.1 - 0.0092 15.2 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KXL42472.1 - 0.01 15.8 0.0 0.018 14.9 0.0 1.5 1 1 0 1 1 1 0 NAD(P)H-binding Semialdhyde_dh PF01118.24 KXL42472.1 - 0.018 15.5 0.0 0.031 14.7 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KXL42472.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KXL42472.1 - 0.15 11.6 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family DUF5121 PF17165.4 KXL42472.1 - 0.15 12.5 0.8 0.35 11.3 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5121) Methyltransf_23 PF13489.6 KXL42473.1 - 4.7e-15 55.8 0.0 6.1e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL42473.1 - 2.5e-13 50.6 0.0 5e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL42473.1 - 1.1e-11 44.8 0.0 1.5e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL42473.1 - 2.4e-11 44.1 0.0 4.1e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL42473.1 - 1.3e-10 41.9 0.0 2.8e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXL42473.1 - 1.6e-08 34.2 0.0 3.2e-08 33.2 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family DREV PF05219.12 KXL42473.1 - 0.0023 17.1 0.0 0.0036 16.5 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_32 PF13679.6 KXL42473.1 - 0.026 14.5 0.0 0.039 13.9 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Mid2 PF04478.12 KXL42473.1 - 0.23 11.3 0.6 0.5 10.2 0.0 1.8 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor ARPC4 PF05856.12 KXL42475.1 - 6.8e-78 260.0 3.6 7.6e-78 259.9 3.6 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) POP1 PF06978.11 KXL42476.1 - 7.8e-70 235.0 15.6 7.8e-70 235.0 15.6 1.6 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 KXL42476.1 - 2.2e-31 108.0 1.5 2.2e-31 108.0 1.5 2.0 2 0 0 2 2 2 1 POPLD (NUC188) domain GCV_T PF01571.21 KXL42476.1 - 0.077 12.4 0.0 2.2 7.6 0.0 2.2 2 0 0 2 2 2 0 Aminomethyltransferase folate-binding domain SMC_N PF02463.19 KXL42477.1 - 9.1e-25 87.4 0.0 1.7e-24 86.5 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KXL42477.1 - 1.8e-19 71.0 2.2 1.8e-19 71.0 2.2 5.3 2 2 2 4 4 2 1 AAA domain AAA_15 PF13175.6 KXL42477.1 - 4.2e-10 39.9 0.1 3.8e-08 33.5 0.0 3.5 2 2 1 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 KXL42477.1 - 6e-05 23.0 1.0 0.0066 16.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXL42477.1 - 0.00031 20.4 0.0 0.00068 19.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Baculo_PEP_C PF04513.12 KXL42477.1 - 0.00058 19.9 11.1 0.51 10.4 0.8 5.1 4 1 0 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_33 PF13671.6 KXL42477.1 - 0.0055 16.9 0.4 0.048 13.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain Occludin_ELL PF07303.13 KXL42477.1 - 0.0082 16.8 2.9 0.0082 16.8 2.9 7.1 3 2 5 8 8 7 2 Occludin homology domain AAA PF00004.29 KXL42477.1 - 0.027 14.9 0.1 0.027 14.9 0.1 2.9 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 KXL42477.1 - 0.077 12.6 0.0 0.077 12.6 0.0 4.1 6 1 1 7 7 7 0 AAA domain DUF2713 PF10897.8 KXL42477.1 - 0.083 12.5 0.1 0.32 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2713) AAA_25 PF13481.6 KXL42477.1 - 0.11 12.1 1.0 0.86 9.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF948 PF06103.11 KXL42477.1 - 0.55 10.5 17.6 12 6.2 0.1 5.6 6 0 0 6 6 5 0 Bacterial protein of unknown function (DUF948) AAA_22 PF13401.6 KXL42477.1 - 0.96 9.7 4.9 12 6.2 0.1 3.2 2 1 0 2 2 2 0 AAA domain NPV_P10 PF05531.12 KXL42477.1 - 2.9 8.4 15.6 51 4.4 3.9 5.8 4 2 0 4 4 4 0 Nucleopolyhedrovirus P10 protein HIT PF01230.23 KXL42477.1 - 3 8.7 4.7 13 6.6 0.5 3.3 3 0 0 3 3 2 0 HIT domain DASH_Dam1 PF08653.10 KXL42477.1 - 8.2 6.3 5.6 46 3.9 0.1 4.3 4 0 0 4 4 4 0 DASH complex subunit Dam1 Mg_trans_NIPA PF05653.14 KXL42478.1 - 2.3e-15 56.5 11.7 3.5e-15 55.9 11.7 1.3 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KXL42478.1 - 0.01 16.0 5.2 0.01 16.0 5.2 3.2 2 2 0 2 2 2 0 EamA-like transporter family DUF1736 PF08409.11 KXL42478.1 - 0.035 14.1 0.1 0.1 12.6 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1736) PUNUT PF16913.5 KXL42478.1 - 0.073 12.3 12.1 5.2 6.2 0.0 2.9 1 1 0 2 2 2 0 Purine nucleobase transmembrane transport Tmemb_55A PF09788.9 KXL42478.1 - 0.33 10.0 0.7 8.4 5.4 0.3 2.4 2 0 0 2 2 2 0 Transmembrane protein 55A zf-C2H2 PF00096.26 KXL42482.1 - 3.8e-10 39.7 10.3 6.4e-06 26.3 0.5 3.3 4 0 0 4 4 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXL42482.1 - 4.2e-08 33.4 15.5 0.00014 22.4 0.5 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXL42482.1 - 1.1e-07 32.0 7.8 1.1e-05 25.7 1.7 3.4 5 0 0 5 5 4 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 KXL42482.1 - 0.00054 19.6 9.2 0.028 14.2 0.1 2.6 2 1 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KXL42482.1 - 0.0014 18.8 7.2 0.012 15.9 0.0 2.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 KXL42482.1 - 0.016 15.6 8.5 0.22 12.0 2.3 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 KXL42482.1 - 0.027 14.2 2.3 3.3 7.5 0.1 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 KXL42482.1 - 0.066 13.5 1.0 0.066 13.5 1.0 2.0 1 1 1 2 2 2 0 C2H2-type zinc ribbon BolA PF01722.18 KXL42482.1 - 0.1 12.9 1.6 2.3 8.6 0.6 2.4 1 1 1 2 2 2 0 BolA-like protein zf-C2H2_6 PF13912.6 KXL42482.1 - 0.16 12.0 12.8 0.43 10.6 0.4 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 KXL42482.1 - 0.19 12.2 0.1 0.19 12.2 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Ribosomal_S26e PF01283.19 KXL42482.1 - 0.29 11.6 1.8 0.35 11.3 0.5 1.7 1 1 1 2 2 2 0 Ribosomal protein S26e C5HCH PF17982.1 KXL42482.1 - 0.7 10.1 8.1 0.17 12.0 2.1 2.3 1 1 1 2 2 2 0 NSD Cys-His rich domain zf-AN1 PF01428.16 KXL42482.1 - 0.94 9.7 8.1 4.1 7.6 1.8 2.5 1 1 1 2 2 2 0 AN1-like Zinc finger Pkinase PF00069.25 KXL42483.1 - 2.4e-66 223.8 0.0 7.1e-65 219.0 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Fungal_KA1 PF16797.5 KXL42483.1 - 1.3e-39 134.6 0.1 3.1e-39 133.4 0.1 1.7 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Pkinase_Tyr PF07714.17 KXL42483.1 - 1.1e-32 113.4 0.0 3.3e-32 111.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KXL42483.1 - 5.6e-05 22.6 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KXL42483.1 - 0.00011 21.9 0.0 0.00032 20.4 0.0 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KXL42483.1 - 0.00015 21.7 0.0 0.0011 19.0 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXL42483.1 - 0.00084 18.4 0.7 0.0014 17.6 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 KXL42483.1 - 0.0048 16.5 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 RIO1 family Rick_17kDa_Anti PF05433.15 KXL42484.1 - 0.0014 18.4 16.0 0.0014 18.4 16.0 3.8 4 0 0 4 4 4 1 Glycine zipper 2TM domain DUF533 PF04391.12 KXL42484.1 - 0.039 13.5 0.1 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF533) AdoMet_MTase PF07757.13 KXL42485.1 - 5.5e-38 129.7 0.0 1.4e-18 67.3 0.0 2.4 2 0 0 2 2 2 2 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 KXL42485.1 - 0.073 13.1 0.0 7 6.6 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Acetyltransf_1 PF00583.25 KXL42486.1 - 2e-10 40.9 0.2 2.6e-10 40.6 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXL42486.1 - 3.6e-09 36.6 0.2 4.7e-09 36.3 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXL42486.1 - 8.6e-09 35.7 0.7 1.2e-08 35.2 0.7 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RGS PF00615.19 KXL42487.1 - 9.5e-07 29.1 0.0 1.7e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain MNHE PF01899.16 KXL42487.1 - 6.7 6.5 7.3 0.65 9.7 1.3 2.2 3 0 0 3 3 3 0 Na+/H+ ion antiporter subunit ANAPC_CDC26 PF10471.9 KXL42488.1 - 0.0029 18.4 3.2 0.0038 18.0 0.2 2.2 2 1 0 2 2 2 1 Anaphase-promoting complex APC subunit CDC26 DUF1664 PF07889.12 KXL42488.1 - 0.047 13.7 0.2 0.068 13.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Zn_ribbon_17 PF17120.5 KXL42489.1 - 1.8e-11 43.5 14.6 5.2e-11 42.0 14.6 1.8 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 KXL42489.1 - 0.00036 21.3 8.9 1 10.3 0.3 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat zf-RING_2 PF13639.6 KXL42489.1 - 0.0041 17.4 10.8 0.0041 17.4 10.8 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXL42489.1 - 0.19 11.6 8.3 0.67 9.9 8.3 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXL42489.1 - 1.8 8.9 11.3 0.19 12.1 4.7 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger domain Elf1 PF05129.13 KXL42490.1 - 0.032 14.3 0.6 0.046 13.8 0.6 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like NAC PF01849.18 KXL42491.1 - 8.9e-23 80.0 0.1 1.7e-22 79.2 0.1 1.5 1 0 0 1 1 1 1 NAC domain Rad21_Rec8_N PF04825.13 KXL42492.1 - 6e-32 110.1 0.0 1.1e-31 109.2 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KXL42492.1 - 3.4e-05 23.1 0.0 6.8e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein UCH PF00443.29 KXL42493.1 - 1.1e-50 172.5 0.1 1.6e-50 172.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXL42493.1 - 1.2e-11 44.8 12.3 6.2e-06 26.0 9.9 2.5 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KXL42493.1 - 7.1e-09 35.3 1.2 1.4e-08 34.4 0.1 2.2 2 0 0 2 2 2 1 Ubiquitin family Homoserine_dh PF00742.19 KXL42493.1 - 0.12 12.3 0.4 0.27 11.2 0.4 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase GSH_synth_ATP PF03917.17 KXL42494.1 - 1.9e-103 346.1 0.0 2.2e-103 346.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KXL42494.1 - 2.1e-26 92.4 0.0 5.6e-26 91.0 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic glutathione synthase MmgE_PrpD PF03972.14 KXL42495.1 - 2e-148 494.6 0.1 2.5e-148 494.3 0.1 1.0 1 0 0 1 1 1 1 MmgE/PrpD family PRK PF00485.18 KXL42495.1 - 0.048 13.4 0.4 0.097 12.4 0.4 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Fes1 PF08609.10 KXL42497.1 - 8.2e-27 93.9 1.0 1.8e-26 92.8 1.0 1.6 1 0 0 1 1 1 1 Nucleotide exchange factor Fes1 Arm PF00514.23 KXL42497.1 - 1e-07 31.8 0.2 0.0022 18.0 0.0 3.4 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KXL42497.1 - 7.4e-05 23.1 0.2 0.00041 20.7 0.0 2.3 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.22 KXL42497.1 - 0.0008 19.5 0.2 0.82 10.1 0.0 3.0 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.6 KXL42497.1 - 0.036 14.6 1.2 1 10.0 0.4 3.0 2 1 1 3 3 3 0 HEAT-like repeat Glyco_hydro_67M PF07488.12 KXL42497.1 - 0.062 12.4 0.0 0.076 12.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 middle domain Ribosomal_S16 PF00886.19 KXL42497.1 - 0.15 12.1 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S16 Med26 PF08711.11 KXL42498.1 - 1.4e-07 31.4 0.0 3.6e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Peroxidase_2 PF01328.17 KXL42501.1 - 2.4e-49 168.4 0.0 3.3e-49 168.0 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 zf-U11-48K PF05253.12 KXL42501.1 - 0.52 10.3 1.9 1.1 9.2 0.1 2.3 2 0 0 2 2 2 0 U11-48K-like CHHC zinc finger Sulfatase PF00884.23 KXL42502.1 - 2.8e-76 256.9 0.1 3.6e-76 256.5 0.1 1.1 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 KXL42502.1 - 0.011 16.0 0.0 0.029 14.6 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4976) DUF4994 PF16385.5 KXL42502.1 - 0.021 14.8 0.2 0.2 11.6 0.1 2.7 3 1 0 3 3 3 0 Domain of unknown function Phosphodiest PF01663.22 KXL42502.1 - 0.022 14.4 0.0 0.17 11.4 0.0 2.2 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KXL42502.1 - 0.096 11.3 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Sugar_tr PF00083.24 KXL42503.1 - 2.5e-89 300.3 25.7 2.8e-89 300.0 25.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL42503.1 - 2.9e-11 42.9 28.6 2.9e-11 42.9 28.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXL42503.1 - 0.0013 17.7 2.5 0.0013 17.7 2.5 2.3 2 0 0 2 2 2 1 MFS_1 like family Use1 PF09753.9 KXL42504.1 - 1.9e-06 27.8 0.0 2.2e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF1241 PF06840.11 KXL42504.1 - 0.033 13.8 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) PTR2 PF00854.21 KXL42505.1 - 0.0017 17.2 0.0 0.0026 16.7 0.0 1.2 1 0 0 1 1 1 1 POT family Rax2 PF12768.7 KXL42505.1 - 0.011 15.2 0.2 0.011 15.2 0.2 1.6 2 0 0 2 2 2 0 Cortical protein marker for cell polarity Amnionless PF14828.6 KXL42505.1 - 0.011 14.6 0.0 0.015 14.2 0.0 1.1 1 0 0 1 1 1 0 Amnionless SKG6 PF08693.10 KXL42505.1 - 0.03 13.7 2.7 0.064 12.7 2.7 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TMEM154 PF15102.6 KXL42505.1 - 0.065 13.1 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 TMEM154 protein family Mid2 PF04478.12 KXL42505.1 - 0.33 10.8 8.1 0.98 9.3 8.1 1.7 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor CHCH PF06747.13 KXL42506.1 - 2.4e-05 24.3 4.4 2.4e-05 24.3 4.4 2.6 3 0 0 3 3 3 1 CHCH domain CX9C PF16860.5 KXL42506.1 - 0.0018 18.2 2.7 0.0018 18.2 2.7 2.4 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 KXL42506.1 - 0.083 12.9 10.0 0.52 10.4 2.4 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.16 KXL42506.1 - 1 9.6 9.1 1.4 9.2 5.3 2.6 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Pet191_N PF10203.9 KXL42506.1 - 3.8 7.9 8.6 1.6e+02 2.7 8.7 2.8 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Nup54 PF13874.6 KXL42507.1 - 4.7e-39 133.7 3.4 4.7e-39 133.7 3.4 2.3 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nup54_57_C PF18570.1 KXL42507.1 - 1.8e-07 30.6 5.9 1.8e-07 30.6 5.9 1.7 2 0 0 2 2 2 1 NUP57/Nup54 C-terminal domain HOOK PF05622.12 KXL42507.1 - 0.0048 15.1 13.1 0.0071 14.6 13.1 1.2 1 0 0 1 1 1 1 HOOK protein Wtap PF17098.5 KXL42507.1 - 0.028 14.4 10.8 0.14 12.1 10.8 2.1 1 1 0 1 1 1 0 WTAP/Mum2p family DUF4154 PF13689.6 KXL42507.1 - 0.054 13.7 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 YfiR/HmsC-like DYW_deaminase PF14432.6 KXL42507.1 - 0.062 13.2 0.1 11 5.9 0.0 3.3 2 2 1 3 3 3 0 DYW family of nucleic acid deaminases Uso1_p115_C PF04871.13 KXL42507.1 - 1 9.7 8.4 0.36 11.2 4.7 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region SHE3 PF17078.5 KXL42507.1 - 3.1 7.5 9.1 0.79 9.4 3.7 2.0 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 Val_tRNA-synt_C PF10458.9 KXL42507.1 - 7.3 7.0 10.0 0.53 10.6 1.0 3.2 3 1 2 5 5 5 0 Valyl tRNA synthetase tRNA binding arm bZIP_1 PF00170.21 KXL42507.1 - 8.4 6.6 9.9 11 6.3 0.4 3.3 3 0 0 3 3 3 0 bZIP transcription factor Spc24 PF08286.11 KXL42507.1 - 9.3 6.6 10.3 7.9e+02 0.4 7.9 3.3 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 adh_short_C2 PF13561.6 KXL42510.1 - 8.9e-57 192.3 2.3 1.1e-56 192.1 2.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL42510.1 - 2.3e-43 148.0 4.3 2.7e-43 147.7 4.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL42510.1 - 4.5e-14 52.8 2.2 6.3e-14 52.3 2.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL42510.1 - 0.00029 20.4 1.3 0.0024 17.3 1.3 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXL42510.1 - 0.00092 18.4 0.1 0.0015 17.7 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KXL42510.1 - 0.0047 16.4 0.4 0.0092 15.4 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 KXL42510.1 - 0.0047 16.8 0.4 0.0089 15.9 0.4 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KXL42510.1 - 0.006 17.1 0.9 0.016 15.7 0.9 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.6 KXL42510.1 - 0.016 15.1 1.6 0.023 14.6 1.6 1.5 1 1 0 1 1 1 0 NAD(P)H-binding 3Beta_HSD PF01073.19 KXL42510.1 - 0.023 13.7 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KXL42510.1 - 0.028 13.5 2.2 0.31 10.1 0.4 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain ApbA PF02558.16 KXL42510.1 - 0.069 12.8 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 KXL42510.1 - 0.073 13.3 0.2 0.16 12.2 0.2 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DAO PF01266.24 KXL42511.1 - 6e-65 220.1 3.2 7.3e-65 219.8 3.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXL42511.1 - 8.5e-08 31.7 0.7 0.0033 16.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 KXL42511.1 - 1.4e-07 31.9 0.1 0.0077 16.8 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXL42511.1 - 2.3e-07 30.3 0.2 0.014 14.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXL42511.1 - 2.7e-06 27.5 0.1 6.6e-06 26.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KXL42511.1 - 1.5e-05 24.5 0.0 4.2e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase MCRA PF06100.11 KXL42511.1 - 0.00028 19.8 0.3 0.0085 14.9 0.1 2.1 2 0 0 2 2 2 1 MCRA family Trp_halogenase PF04820.14 KXL42511.1 - 0.0043 16.0 0.4 0.016 14.1 0.1 1.8 2 0 0 2 2 2 1 Tryptophan halogenase GMC_oxred_N PF00732.19 KXL42511.1 - 0.0083 15.5 0.1 0.19 11.0 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase Thi4 PF01946.17 KXL42511.1 - 0.033 13.4 0.2 0.084 12.1 0.2 1.6 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 KXL42511.1 - 0.064 13.2 0.5 0.24 11.4 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Actin PF00022.19 KXL42512.1 - 2.7e-150 500.5 0.0 1.1e-149 498.5 0.0 1.7 1 1 0 1 1 1 1 Actin Met_gamma_lyase PF06838.11 KXL42512.1 - 0.15 10.6 0.0 0.22 10.0 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase AA_permease_2 PF13520.6 KXL42515.1 - 3.2e-61 207.5 44.8 4.2e-61 207.1 44.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXL42515.1 - 3.1e-24 85.4 30.2 3.1e-24 85.4 30.2 2.1 2 0 0 2 2 2 1 Amino acid permease Thaumatin PF00314.17 KXL42516.1 - 0.0041 16.8 3.2 0.16 11.6 0.0 3.0 1 1 1 3 3 3 2 Thaumatin family DUF3128 PF11326.8 KXL42517.1 - 3.8e-28 97.7 2.9 5.4e-28 97.2 2.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) DUF2011 PF09428.10 KXL42518.1 - 1.9e-22 79.3 0.2 8.4e-22 77.2 0.0 2.1 2 1 0 2 2 2 1 Fungal protein of unknown function (DUF2011) DUF1682 PF07946.14 KXL42518.1 - 0.013 14.7 10.8 0.018 14.3 10.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Med19 PF10278.9 KXL42518.1 - 0.54 10.2 9.1 0.79 9.6 9.1 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Presenilin PF01080.17 KXL42518.1 - 3.1 6.5 5.5 3.9 6.1 5.5 1.1 1 0 0 1 1 1 0 Presenilin ArabFuran-catal PF09206.11 KXL42520.1 - 3.6e-129 430.6 5.4 4.1e-129 430.4 5.4 1.0 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic DUF1768 PF08719.11 KXL42521.1 - 1.5e-24 87.0 0.0 2.1e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Tmp39 PF10271.9 KXL42521.1 - 0.2 10.6 0.0 0.23 10.4 0.0 1.0 1 0 0 1 1 1 0 Putative transmembrane protein GST_N_3 PF13417.6 KXL42522.1 - 7.1e-14 52.0 0.0 1.4e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXL42522.1 - 2.3e-11 43.8 0.0 4.3e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXL42522.1 - 9.9e-09 35.4 0.0 1.6e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXL42522.1 - 8.1e-05 22.6 0.1 0.00014 21.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KXL42522.1 - 0.00014 22.0 0.0 0.00025 21.2 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_C_5 PF16865.5 KXL42522.1 - 0.005 17.4 0.0 0.0079 16.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HLH PF00010.26 KXL42523.1 - 1.5e-12 47.2 0.1 3.2e-12 46.2 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SLX9 PF15341.6 KXL42523.1 - 0.017 15.6 0.7 0.017 15.6 0.7 1.5 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 Syntaxin-6_N PF09177.11 KXL42523.1 - 0.048 14.2 3.7 0.054 14.1 0.8 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Reticulon PF02453.17 KXL42524.1 - 4.4e-29 101.5 5.1 5.5e-29 101.2 4.0 1.7 2 0 0 2 2 2 1 Reticulon Cofac_haem_bdg PF04187.13 KXL42524.1 - 0.37 10.7 3.8 14 5.6 0.0 2.6 3 0 0 3 3 3 0 Haem-binding uptake, Tiki superfamily, ChaN DUF883 PF05957.13 KXL42524.1 - 0.49 11.0 2.4 0.69 10.6 0.4 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) NAD_binding_10 PF13460.6 KXL42525.1 - 4.3e-06 26.8 0.0 7.5e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KXL42525.1 - 0.00024 20.4 0.0 0.0067 15.6 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.21 KXL42525.1 - 0.007 15.9 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXL42525.1 - 0.09 11.9 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Granulin PF00396.18 KXL42526.1 - 4.6 7.7 17.0 4.6 7.7 2.0 3.2 1 1 1 2 2 2 0 Granulin Stn1 PF10451.9 KXL42527.1 - 2.3e-12 46.4 0.7 1.1e-05 24.5 0.1 2.1 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 KXL42527.1 - 0.01 15.8 1.0 2.6 8.1 0.1 2.5 2 1 0 2 2 2 0 OB-fold nucleic acid binding domain tRNA_anti-like PF12869.7 KXL42527.1 - 0.28 10.8 3.1 7.8 6.1 0.2 2.7 2 1 1 3 3 3 0 tRNA_anti-like Ribonuclease_T2 PF00445.18 KXL42528.1 - 1.9e-18 67.4 8.8 1.1e-15 58.3 7.1 2.2 1 1 1 2 2 2 2 Ribonuclease T2 family Trm112p PF03966.16 KXL42528.1 - 0.022 15.3 0.2 0.41 11.2 0.2 2.4 1 1 0 1 1 1 0 Trm112p-like protein SnoaL_2 PF12680.7 KXL42529.1 - 0.00028 21.5 0.0 0.00041 20.9 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain Inv-AAD PF18785.1 KXL42530.1 - 4.2e-51 172.2 0.1 4.9e-51 171.9 0.1 1.1 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 KXL42530.1 - 4.5e-14 52.1 0.5 6.8e-14 51.6 0.5 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 KXL42530.1 - 0.00012 22.0 0.1 0.00015 21.7 0.1 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain Glyco_hydro_76 PF03663.14 KXL42531.1 - 1.9e-137 458.7 19.9 2.4e-137 458.4 19.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Holin_SPP1 PF04688.13 KXL42531.1 - 0.021 14.9 0.1 0.056 13.6 0.1 1.7 1 0 0 1 1 1 0 SPP1 phage holin Glyco_hydro_88 PF07470.13 KXL42531.1 - 0.056 12.5 14.9 0.045 12.8 0.7 3.2 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 ECH_1 PF00378.20 KXL42532.1 - 6.3e-22 78.1 0.0 7.5e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXL42532.1 - 0.00016 21.3 0.0 0.0002 20.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KXL42532.1 - 0.0045 16.9 0.0 2 8.4 0.0 2.3 2 0 0 2 2 2 2 Peptidase family S49 Herpes_IE1 PF07340.11 KXL42532.1 - 0.014 14.4 0.0 0.019 13.9 0.0 1.1 1 0 0 1 1 1 0 Cytomegalovirus IE1 protein ATG_C PF09333.11 KXL42533.1 - 0.12 12.7 0.5 0.29 11.5 0.5 1.8 1 1 0 1 1 1 0 Autophagy-related protein C terminal domain Vps36_ESCRT-II PF11605.8 KXL42534.1 - 0.0039 17.3 0.0 0.0069 16.5 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.20 KXL42534.1 - 0.076 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 GRAM domain SAPS PF04499.15 KXL42535.1 - 1.9e-186 620.6 1.4 1.1e-184 614.8 0.0 2.3 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein tRNA_lig_CPD PF08302.11 KXL42535.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain Mannosyl_trans2 PF04188.13 KXL42536.1 - 5.1e-48 164.5 15.1 6.2e-48 164.2 15.1 1.0 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) FAM222A PF15258.6 KXL42536.1 - 0.082 12.0 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein family of FAM222A Nucleo_P87 PF07267.11 KXL42538.1 - 1.8 7.3 4.2 2.3 6.9 4.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Sfi1 PF08457.10 KXL42540.1 - 7.1e-129 430.9 102.2 2.7e-127 425.7 92.4 2.1 1 1 1 2 2 2 2 Sfi1 spindle body protein Phage_term_sma PF07141.11 KXL42540.1 - 0.18 11.6 1.1 0.61 9.8 0.1 2.3 2 0 0 2 2 2 0 Putative bacteriophage terminase small subunit CX9C PF16860.5 KXL42541.1 - 0.00025 21.0 1.6 0.00034 20.6 1.6 1.2 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 KXL42541.1 - 0.0095 16.0 1.8 0.016 15.3 1.8 1.5 1 1 0 1 1 1 1 CHCH domain RPN6_C_helix PF18503.1 KXL42542.1 - 1.3 8.8 2.8 26 4.7 0.2 2.9 3 0 0 3 3 3 0 26S proteasome subunit RPN6 C-terminal helix domain adh_short PF00106.25 KXL42543.1 - 2.7e-41 141.2 0.4 4e-41 140.6 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL42543.1 - 3.2e-31 108.7 0.7 4.1e-31 108.3 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL42543.1 - 8.6e-10 38.8 0.5 1.2e-09 38.3 0.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL42543.1 - 1e-05 25.1 0.4 5.8e-05 22.7 0.4 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KXL42543.1 - 0.0006 19.3 0.0 0.00084 18.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.13 KXL42543.1 - 0.026 14.1 0.5 0.22 11.0 0.5 1.9 2 0 0 2 2 2 0 NmrA-like family RmlD_sub_bind PF04321.17 KXL42543.1 - 0.043 12.9 0.2 0.081 12.0 0.2 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain YjeF_N PF03853.15 KXL42543.1 - 0.046 13.6 1.3 0.07 13.0 0.4 1.7 2 0 0 2 2 2 0 YjeF-related protein N-terminus Ribosomal_S4e PF00900.20 KXL42544.1 - 3.8e-37 126.0 0.2 8.3e-37 124.9 0.2 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 KXL42544.1 - 3.6e-24 84.2 0.0 6.5e-24 83.3 0.0 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 KXL42544.1 - 1.4e-17 63.5 6.5 2.7e-17 62.6 6.5 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 KXL42544.1 - 8.6e-08 31.8 0.0 1.6e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 KXL42544.1 - 0.00015 21.6 2.9 0.00015 21.6 2.9 2.8 3 0 0 3 3 3 1 KOW motif Abhydrolase_3 PF07859.13 KXL42545.1 - 1.6e-49 168.7 0.0 2e-49 168.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXL42545.1 - 4.6e-06 25.8 0.1 1.7e-05 23.9 0.1 1.8 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KXL42545.1 - 0.00041 19.9 0.0 0.04 13.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 KXL42545.1 - 0.035 13.7 0.0 0.077 12.5 0.0 1.5 2 0 0 2 2 2 0 Dienelactone hydrolase family Esterase_phd PF10503.9 KXL42545.1 - 0.11 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase AXE1 PF05448.12 KXL42545.1 - 0.13 10.9 0.0 0.24 10.1 0.0 1.4 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) FACT-Spt16_Nlob PF14826.6 KXL42546.1 - 1.6e-56 190.6 0.4 7.9e-56 188.3 0.4 2.3 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain SPT16 PF08644.11 KXL42546.1 - 2.5e-56 190.0 0.1 2.5e-56 190.0 0.1 3.2 4 0 0 4 4 4 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 KXL42546.1 - 2.9e-23 82.7 0.0 5.9e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KXL42546.1 - 3.7e-17 62.5 0.4 1.4e-16 60.7 0.1 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DUF592 PF04574.13 KXL42546.1 - 0.078 12.7 0.6 0.3 10.9 0.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF592) Arm-DNA-bind_4 PF14657.6 KXL42546.1 - 0.22 11.3 4.9 1.3 8.8 4.9 2.4 1 0 0 1 1 1 0 Arm DNA-binding domain Mito_carr PF00153.27 KXL42547.1 - 1.1e-15 57.3 7.8 3.7e-13 49.2 0.2 3.5 3 1 0 3 3 3 2 Mitochondrial carrier protein DUF4148 PF13663.6 KXL42548.1 - 1.1 9.4 3.8 1.6 9.0 3.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4148) Atg14 PF10186.9 KXL42549.1 - 0.0018 17.4 12.4 0.0036 16.4 12.4 1.4 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Csm2_III-A PF03750.13 KXL42549.1 - 0.002 18.9 0.2 0.0041 17.9 0.2 1.5 1 0 0 1 1 1 1 Csm2 Type III-A CALCOCO1 PF07888.11 KXL42549.1 - 0.0025 16.8 12.3 0.0034 16.3 12.3 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Lipoprotein_7 PF01540.16 KXL42549.1 - 0.0043 16.4 0.4 0.0052 16.1 0.4 1.2 1 0 0 1 1 1 1 Adhesin lipoprotein Spc7 PF08317.11 KXL42549.1 - 0.007 15.3 17.1 0.077 11.9 3.6 2.1 1 1 0 2 2 2 2 Spc7 kinetochore protein AAA_13 PF13166.6 KXL42549.1 - 0.008 14.9 3.0 0.012 14.3 3.0 1.3 1 0 0 1 1 1 1 AAA domain TMF_TATA_bd PF12325.8 KXL42549.1 - 0.012 15.8 14.0 0.014 15.6 3.4 2.9 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding MscS_porin PF12795.7 KXL42549.1 - 0.023 14.2 20.2 0.052 13.1 20.2 1.7 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF713 PF05218.14 KXL42549.1 - 0.026 14.3 1.1 0.35 10.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF713) Prefoldin_2 PF01920.20 KXL42549.1 - 0.029 14.3 12.7 0.96 9.4 0.2 3.5 1 1 2 4 4 4 0 Prefoldin subunit ABC_tran_CTD PF16326.5 KXL42549.1 - 0.03 14.6 18.2 0.09 13.0 0.2 3.7 1 1 2 3 3 3 0 ABC transporter C-terminal domain Fib_alpha PF08702.10 KXL42549.1 - 0.035 14.3 3.4 0.055 13.6 3.4 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 KXL42549.1 - 0.045 14.1 4.2 23 5.5 0.1 3.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF948 PF06103.11 KXL42549.1 - 0.089 13.1 1.1 0.2 12.0 0.3 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4407 PF14362.6 KXL42549.1 - 0.089 12.1 9.1 0.18 11.1 9.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 KXL42549.1 - 0.095 13.2 3.1 1 9.9 0.2 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein BRE1 PF08647.11 KXL42549.1 - 0.1 12.7 12.8 0.059 13.4 5.0 2.5 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase ATG16 PF08614.11 KXL42549.1 - 0.11 12.7 14.7 0.53 10.5 4.4 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF5082 PF16888.5 KXL42549.1 - 0.11 12.7 9.0 2.1 8.6 0.7 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) GAS PF13851.6 KXL42549.1 - 0.14 11.4 12.9 0.18 11.1 2.0 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 KXL42549.1 - 0.16 12.0 3.5 4.1 7.4 0.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 KXL42549.1 - 0.16 12.3 6.6 0.18 12.1 1.5 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FUSC PF04632.12 KXL42549.1 - 0.23 10.0 5.0 0.26 9.8 5.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family UPF0242 PF06785.11 KXL42549.1 - 0.23 11.5 12.9 0.56 10.3 12.7 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Baculo_PEP_C PF04513.12 KXL42549.1 - 0.23 11.5 3.6 1.6 8.7 0.3 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fez1 PF06818.15 KXL42549.1 - 0.24 11.8 14.0 1.1 9.7 14.0 1.8 1 1 0 1 1 1 0 Fez1 YabA PF06156.13 KXL42549.1 - 0.28 11.8 8.4 0.53 10.9 0.9 2.4 2 1 0 2 2 2 0 Initiation control protein YabA Phage_GP20 PF06810.11 KXL42549.1 - 0.35 10.7 6.0 1.5 8.6 3.9 2.8 1 1 0 1 1 1 0 Phage minor structural protein GP20 PEARLI-4 PF05278.12 KXL42549.1 - 0.37 10.4 6.1 0.092 12.3 0.7 2.0 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) Osmo_CC PF08946.10 KXL42549.1 - 0.44 10.8 0.1 0.44 10.8 0.1 4.0 3 2 2 5 5 4 0 Osmosensory transporter coiled coil DUF4201 PF13870.6 KXL42549.1 - 0.45 10.2 11.7 0.46 10.2 2.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) CENP-F_leu_zip PF10473.9 KXL42549.1 - 0.61 10.1 15.4 0.27 11.3 8.3 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG2 PF06148.11 KXL42549.1 - 0.8 9.8 4.7 4.8 7.3 0.7 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF812 PF05667.11 KXL42549.1 - 0.96 8.2 14.4 1.2 7.9 4.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) HAP1_N PF04849.13 KXL42549.1 - 1.2 8.3 15.4 7.6 5.6 11.0 2.4 1 1 2 3 3 3 0 HAP1 N-terminal conserved region CorA PF01544.18 KXL42549.1 - 1.2 8.4 4.1 2.5 7.3 0.1 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF16 PF01519.16 KXL42549.1 - 1.4 9.4 9.8 2.3 8.8 2.2 2.6 1 1 1 2 2 2 0 Protein of unknown function DUF16 YlqD PF11068.8 KXL42549.1 - 2.1 8.7 11.7 0.36 11.2 1.1 2.2 2 0 0 2 2 2 0 YlqD protein DUF4200 PF13863.6 KXL42549.1 - 2.4 8.6 16.3 3.7 8.0 3.7 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Seryl_tRNA_N PF02403.22 KXL42549.1 - 2.8 8.2 16.9 3.2 8.0 2.1 3.3 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Syntaxin-6_N PF09177.11 KXL42549.1 - 3.5 8.3 8.6 15 6.2 0.5 2.4 1 1 2 3 3 3 0 Syntaxin 6, N-terminal SHE3 PF17078.5 KXL42549.1 - 3.8 7.2 10.3 10 5.7 1.1 2.5 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 OmpH PF03938.14 KXL42549.1 - 4.3 7.7 20.2 3.2 8.1 5.2 2.2 1 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Fmp27_WPPW PF10359.9 KXL42549.1 - 4.9 5.9 7.9 9.3 5.0 7.9 1.6 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Exonuc_VII_L PF02601.15 KXL42549.1 - 5 6.6 11.7 23 4.4 11.7 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit Prefoldin PF02996.17 KXL42549.1 - 5.2 7.0 11.4 3.8 7.4 0.6 3.5 2 2 1 3 3 3 0 Prefoldin subunit DUF4472 PF14739.6 KXL42549.1 - 5.4 7.8 12.2 2.4 8.9 2.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) FapA PF03961.13 KXL42549.1 - 5.8 5.4 11.7 1.9 7.0 2.3 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A HIP1_clath_bdg PF16515.5 KXL42549.1 - 6 7.5 14.6 6.9 7.3 2.2 2.6 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FAM76 PF16046.5 KXL42549.1 - 8.8 5.6 10.9 3.3 7.0 1.4 2.1 1 1 1 2 2 2 0 FAM76 protein ACCA PF03255.14 KXL42549.1 - 9 6.2 8.5 19 5.1 1.5 2.4 2 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF724 PF05266.14 KXL42549.1 - 9.1 6.1 11.3 3.4 7.4 1.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF724) adh_short_C2 PF13561.6 KXL42550.1 - 1.1e-53 182.2 0.7 3.7e-53 180.5 0.7 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL42550.1 - 1.6e-45 155.0 1.5 6.6e-45 153.0 1.5 1.8 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 KXL42550.1 - 8.4e-06 25.4 0.3 9.8e-05 21.9 0.3 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXL42550.1 - 5.7e-05 23.1 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KXL42550.1 - 0.002 17.5 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.18 KXL42550.1 - 0.006 16.5 0.1 0.011 15.6 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KXL42550.1 - 0.026 15.0 0.0 0.054 13.9 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 KXL42550.1 - 0.058 13.5 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FMN_dh PF01070.18 KXL42551.1 - 7.8e-105 350.7 0.1 1.1e-104 350.2 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KXL42551.1 - 3.5e-17 62.3 0.0 1e-16 60.8 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain ThiG PF05690.14 KXL42551.1 - 0.00024 20.5 1.4 0.0098 15.2 0.1 2.6 3 0 0 3 3 3 1 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 KXL42551.1 - 0.0033 16.6 0.1 0.0071 15.5 0.0 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.25 KXL42551.1 - 0.0084 15.1 3.8 0.019 14.0 0.3 2.6 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain Dus PF01207.17 KXL42551.1 - 0.042 12.9 0.1 0.12 11.4 0.0 1.8 1 1 0 1 1 1 0 Dihydrouridine synthase (Dus) NMO PF03060.15 KXL42551.1 - 0.055 12.9 0.2 0.1 12.0 0.2 1.5 1 0 0 1 1 1 0 Nitronate monooxygenase PFU PF09070.11 KXL42552.1 - 3.1e-06 27.4 0.2 6.9e-06 26.3 0.2 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) XkdW PF09636.10 KXL42552.1 - 0.23 11.6 0.8 1.9 8.6 0.0 2.3 2 0 0 2 2 2 0 XkdW protein SpoIIIAH PF12685.7 KXL42552.1 - 2.6 7.8 5.4 0.81 9.5 0.8 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein EHN PF06441.12 KXL42553.1 - 4.2e-06 27.1 0.0 7.6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus OAR PF03826.17 KXL42555.1 - 0.024 14.5 0.3 0.024 14.5 0.3 2.6 2 1 0 2 2 2 0 OAR domain SURF6 PF04935.12 KXL42556.1 - 1.9e-37 129.0 39.5 1.9e-37 129.0 39.5 3.9 2 1 0 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.6 KXL42556.1 - 2e-12 47.5 0.3 2e-12 47.5 0.3 6.4 4 1 0 4 4 4 1 60S ribosome biogenesis protein Rrp14 IMS PF00817.20 KXL42558.1 - 4.2e-37 127.5 0.0 1e-36 126.2 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 KXL42558.1 - 1.4e-23 83.1 2.0 2.9e-23 82.1 2.0 1.6 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain UBM PF14377.6 KXL42558.1 - 6.3e-16 57.2 17.7 1.4e-06 27.6 0.2 4.8 4 0 0 4 4 4 3 Ubiquitin binding region IMS_C PF11799.8 KXL42558.1 - 2.1e-14 54.2 0.0 5.9e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 KXL42558.1 - 6.4e-11 42.5 0.0 3.3e-10 40.2 0.0 2.3 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KXL42558.1 - 0.0001 22.6 0.0 0.00031 21.1 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KXL42558.1 - 0.00022 21.4 0.0 0.00084 19.6 0.0 2.0 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain mCpol PF18182.1 KXL42558.1 - 0.00036 20.8 0.0 0.0011 19.3 0.0 1.8 1 0 0 1 1 1 1 minimal CRISPR polymerase domain PTCB-BRCT PF12738.7 KXL42558.1 - 0.023 14.7 0.2 0.1 12.6 0.0 2.2 2 0 0 2 2 2 0 twin BRCT domain RCC_reductase PF06405.11 KXL42558.1 - 0.042 13.0 0.0 0.11 11.7 0.0 1.7 1 0 0 1 1 1 0 Red chlorophyll catabolite reductase (RCC reductase) IMS_HHH PF11798.8 KXL42558.1 - 0.044 14.1 2.1 0.13 12.7 0.1 3.0 3 0 0 3 3 3 0 IMS family HHH motif NPL PF17800.1 KXL42559.1 - 6.1e-34 116.7 1.1 6.1e-34 116.7 1.1 2.8 2 2 0 2 2 2 1 Nucleoplasmin-like domain FKBP_C PF00254.28 KXL42559.1 - 9e-31 106.1 0.0 3.8e-30 104.1 0.0 2.1 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase PP-binding PF00550.25 KXL42560.1 - 1.2e-11 44.8 0.2 1.7e-11 44.3 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KXL42560.1 - 1.1e-06 28.7 0.1 1.6e-06 28.3 0.1 1.2 1 0 0 1 1 1 1 Acyl-carrier GPP34 PF05719.11 KXL42561.1 - 2.3e-66 223.7 0.1 3.1e-66 223.3 0.1 1.2 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) SNF5 PF04855.12 KXL42562.1 - 1.8e-60 204.7 0.2 4.4e-59 200.1 0.2 2.2 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 SKG6 PF08693.10 KXL42564.1 - 0.0003 20.1 1.5 0.00053 19.3 1.5 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Alpha_GJ PF03229.13 KXL42564.1 - 0.007 16.9 0.1 0.016 15.7 0.1 1.6 1 0 0 1 1 1 1 Alphavirus glycoprotein J Gram_pos_anchor PF00746.21 KXL42564.1 - 0.056 13.4 0.2 0.1 12.5 0.2 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Adeno_E3_CR2 PF02439.15 KXL42564.1 - 0.09 12.5 0.5 0.09 12.5 0.5 2.0 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Phage_HK97_TLTM PF06120.11 KXL42564.1 - 0.096 11.9 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Tail length tape measure protein TMEM154 PF15102.6 KXL42564.1 - 0.14 12.1 0.1 0.27 11.2 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family Mucin15 PF15672.5 KXL42566.1 - 0.0013 18.3 0.8 0.0013 18.3 0.8 1.8 2 0 0 2 2 2 1 Cell-membrane associated Mucin15 Glycophorin_A PF01102.18 KXL42566.1 - 0.0019 18.4 0.4 0.004 17.4 0.4 1.5 1 0 0 1 1 1 1 Glycophorin A Mid2 PF04478.12 KXL42566.1 - 0.036 13.9 0.2 0.09 12.6 0.1 1.7 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Sugar_tr PF00083.24 KXL42566.1 - 0.24 10.2 1.5 0.37 9.6 1.5 1.2 1 0 0 1 1 1 0 Sugar (and other) transporter MreB_Mbl PF06723.13 KXL42567.1 - 6.8e-05 21.8 0.0 0.064 12.1 0.0 2.6 2 0 0 2 2 2 2 MreB/Mbl protein HSP70 PF00012.20 KXL42567.1 - 0.00068 18.0 0.0 0.0012 17.1 0.0 1.3 1 0 0 1 1 1 1 Hsp70 protein StbA PF06406.11 KXL42567.1 - 0.025 13.8 0.0 0.13 11.5 0.0 1.9 2 0 0 2 2 2 0 StbA protein CPDase PF07823.11 KXL42568.1 - 1.4e-32 113.0 0.0 1.6e-32 112.8 0.0 1.0 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 KXL42568.1 - 6.9e-05 22.8 0.0 0.4 10.6 0.0 2.2 2 0 0 2 2 2 2 2'-5' RNA ligase superfamily WD40 PF00400.32 KXL42569.1 - 1.3e-43 146.1 14.8 5.7e-09 36.5 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL42569.1 - 1.2e-06 28.7 1.5 0.86 9.9 0.1 5.2 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXL42569.1 - 0.028 13.1 0.3 5.8 5.4 0.1 2.7 1 1 2 3 3 3 0 Nucleoporin Nup120/160 COA2 PF17051.5 KXL42570.1 - 0.008 16.2 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 UreE_N PF02814.15 KXL42570.1 - 0.063 12.9 0.0 0.094 12.3 0.0 1.2 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain Mnd1 PF03962.15 KXL42572.1 - 1.4e-21 76.5 0.1 4e-21 75.0 0.1 1.8 1 0 0 1 1 1 1 Mnd1 HTH domain LZ3wCH PF18517.1 KXL42572.1 - 0.0015 18.6 0.1 0.0015 18.6 0.1 2.6 3 1 0 3 3 3 1 Leucine zipper with capping helix domain TFIIE_beta PF02186.15 KXL42572.1 - 0.089 13.1 0.4 0.2 11.9 0.1 1.9 2 0 0 2 2 2 0 TFIIE beta subunit core domain F_actin_bind PF08919.10 KXL42572.1 - 0.1 12.7 1.2 0.74 9.9 0.0 2.5 3 0 0 3 3 3 0 F-actin binding V_ATPase_I PF01496.19 KXL42572.1 - 0.1 10.5 1.3 0.12 10.3 1.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TPR_MLP1_2 PF07926.12 KXL42572.1 - 0.15 12.2 11.4 0.64 10.1 2.8 2.5 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.9 KXL42572.1 - 0.17 11.0 3.6 0.2 10.7 3.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF724 PF05266.14 KXL42572.1 - 0.53 10.1 5.2 1.8 8.4 4.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Cortex-I_coil PF09304.10 KXL42572.1 - 0.75 10.0 10.3 0.22 11.8 4.2 2.7 1 1 1 2 2 2 0 Cortexillin I, coiled coil TBCA PF02970.16 KXL42572.1 - 1 9.8 12.9 0.092 13.1 3.3 3.1 2 1 3 5 5 5 0 Tubulin binding cofactor A Fib_alpha PF08702.10 KXL42572.1 - 1.2 9.3 7.9 4.5 7.4 0.9 3.1 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family APG6_N PF17675.1 KXL42572.1 - 1.4 9.5 11.5 0.57 10.7 7.2 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 KXL42572.1 - 2.6 8.1 11.6 2.4 8.2 8.5 2.4 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ribosomal_L29 PF00831.23 KXL42572.1 - 6.6 6.8 7.3 1.9 8.5 0.2 3.0 3 0 0 3 3 3 0 Ribosomal L29 protein UAF_Rrn10 PF05234.11 KXL42573.1 - 0.0017 18.6 0.0 0.0027 17.9 0.0 1.3 1 0 0 1 1 1 1 UAF complex subunit Rrn10 WD40 PF00400.32 KXL42574.1 - 6.6e-19 67.9 18.4 5.4e-06 27.0 0.8 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL42574.1 - 4.3e-09 36.5 0.1 0.055 13.8 0.0 5.3 6 1 1 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Sulfotransfer_4 PF17784.1 KXL42575.1 - 1e-65 221.6 0.0 1.3e-65 221.3 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXL42575.1 - 3.2e-05 24.4 0.1 0.0015 19.0 0.0 2.5 2 1 1 3 3 3 1 Sulfotransferase family TPR_14 PF13428.6 KXL42576.1 - 3.5e-13 49.2 9.0 0.028 15.2 0.2 6.2 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 KXL42576.1 - 1.5e-05 25.4 0.0 1.7 9.2 0.0 3.7 2 1 0 3 3 3 2 Tetratricopeptide repeat Suf PF05843.14 KXL42576.1 - 3.3e-05 24.0 9.6 0.00088 19.3 0.7 3.6 2 1 1 3 3 3 2 Suppressor of forked protein (Suf) TPR_12 PF13424.6 KXL42576.1 - 0.011 16.0 1.9 0.76 10.1 0.2 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXL42576.1 - 0.023 15.3 2.5 0.77 10.5 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat YdjC PF04794.12 KXL42576.1 - 0.063 13.3 0.4 0.14 12.1 0.1 1.7 2 0 0 2 2 2 0 YdjC-like protein Wzy_C_2 PF11846.8 KXL42576.1 - 0.07 13.1 0.1 0.23 11.4 0.0 1.9 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal zf-CSL PF05207.13 KXL42577.1 - 8.7e-19 67.0 0.7 1.2e-18 66.5 0.7 1.2 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 KXL42577.1 - 1.4e-10 41.2 0.1 2e-10 40.6 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain FAD_binding_3 PF01494.19 KXL42578.1 - 1.8e-23 83.3 0.2 8.9e-16 58.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXL42578.1 - 6.9e-08 32.6 0.7 2.4e-07 30.8 0.7 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXL42578.1 - 3.2e-05 23.7 1.9 0.00011 22.0 1.8 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXL42578.1 - 0.00012 21.3 0.2 0.0002 20.6 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXL42578.1 - 0.00016 21.0 0.2 0.005 16.1 0.4 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXL42578.1 - 0.0093 15.2 0.1 0.017 14.4 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 KXL42578.1 - 0.021 14.2 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ThiF PF00899.21 KXL42578.1 - 0.029 13.7 0.1 0.048 13.0 0.1 1.3 1 0 0 1 1 1 0 ThiF family Trp_halogenase PF04820.14 KXL42578.1 - 0.037 12.9 0.2 0.059 12.2 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 KXL42578.1 - 0.041 14.4 0.1 0.11 13.0 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXL42578.1 - 0.1 11.8 0.1 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXL42578.1 - 0.13 11.3 1.3 0.22 10.6 1.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF1749 PF08538.10 KXL42579.1 - 1.8e-74 250.5 0.0 2e-74 250.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 KXL42579.1 - 1.1e-07 32.7 0.0 1.6e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXL42579.1 - 7.5e-06 25.4 0.0 3.8e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF900 PF05990.12 KXL42579.1 - 0.01 15.4 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Ser_hydrolase PF06821.13 KXL42579.1 - 0.016 15.1 0.0 0.044 13.7 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase Abhydrolase_3 PF07859.13 KXL42579.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KXL42579.1 - 0.18 10.7 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Fer2_3 PF13085.6 KXL42581.1 - 8.8e-32 109.4 0.0 1.4e-31 108.7 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 KXL42581.1 - 2.1e-09 37.8 7.5 2.1e-09 37.8 7.5 2.1 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KXL42581.1 - 1.5e-07 31.7 9.0 1.5e-07 31.7 9.0 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KXL42581.1 - 9.3e-07 28.9 4.1 9.3e-07 28.9 4.1 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KXL42581.1 - 0.01 16.4 6.8 0.01 16.4 6.8 2.5 2 2 1 3 3 3 0 4Fe-4S dicluster domain Fer2 PF00111.27 KXL42581.1 - 0.01 15.7 0.4 0.01 15.7 0.4 2.3 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain SF3a60_bindingd PF12108.8 KXL42581.1 - 0.15 12.0 2.4 0.19 11.6 0.4 2.0 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain Fer4_18 PF13746.6 KXL42581.1 - 0.2 11.9 6.7 0.36 11.1 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 KXL42581.1 - 4 7.7 13.0 15 5.8 10.1 2.8 2 1 1 3 3 3 0 4Fe-4S dicluster domain HAD PF12710.7 KXL42582.1 - 0.00042 20.8 0.1 0.41 11.0 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 KXL42583.1 - 1.4e-62 211.5 0.0 1.7e-62 211.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL42583.1 - 2.9e-31 108.7 0.0 4.7e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXL42583.1 - 2.6e-05 23.7 0.0 3.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXL42583.1 - 0.00055 19.3 0.2 0.00092 18.6 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXL42583.1 - 0.01 15.8 0.6 0.03 14.3 0.4 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family IGR PF09597.10 KXL42584.1 - 1.6e-26 92.2 0.1 2.6e-26 91.5 0.1 1.4 1 0 0 1 1 1 1 IGR protein motif FAD_binding_4 PF01565.23 KXL42586.1 - 2.2e-15 56.6 2.5 5.1e-15 55.4 2.5 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXL42586.1 - 0.00016 21.7 0.1 0.0003 20.8 0.1 1.4 1 0 0 1 1 1 1 Berberine and berberine like Methyltransf_24 PF13578.6 KXL42588.1 - 8e-11 42.9 0.0 1.5e-10 42.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 KXL42588.1 - 8.6e-11 41.4 0.0 1.1e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase CmcI PF04989.12 KXL42588.1 - 0.18 11.5 0.0 0.31 10.7 0.0 1.5 1 1 0 1 1 1 0 Cephalosporin hydroxylase DHQ_synthase PF01761.20 KXL42589.1 - 3.5e-53 180.4 0.0 5.3e-53 179.8 0.0 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 KXL42589.1 - 1.2e-10 41.5 0.0 2.1e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Kinesin PF00225.23 KXL42590.1 - 1.2e-95 320.2 0.0 2.4e-95 319.3 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXL42590.1 - 5e-23 81.7 0.0 1.1e-22 80.6 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Porin_7 PF16956.5 KXL42590.1 - 0.11 12.1 0.9 0.18 11.4 0.9 1.2 1 0 0 1 1 1 0 Putative general bacterial porin XLF PF09302.11 KXL42590.1 - 5.7 7.1 9.5 3.6 7.7 1.7 3.1 2 1 1 3 3 3 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component MFS_1 PF07690.16 KXL42592.1 - 1.9e-51 175.1 34.7 1.9e-51 175.1 34.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXL42592.1 - 1.1e-07 30.7 1.1 2.1e-07 29.8 1.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXL42592.1 - 2.4e-05 23.4 19.8 2.4e-05 23.4 19.8 3.1 2 1 0 2 2 2 1 Sugar (and other) transporter FPN1 PF06963.12 KXL42592.1 - 0.0023 16.6 0.0 0.0043 15.7 0.0 1.3 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Trm112p PF03966.16 KXL42593.1 - 5.2e-15 55.8 0.1 7.8e-15 55.2 0.1 1.3 1 0 0 1 1 1 1 Trm112p-like protein UAF_Rrn10 PF05234.11 KXL42593.1 - 0.19 11.9 0.0 0.27 11.5 0.0 1.2 1 0 0 1 1 1 0 UAF complex subunit Rrn10 DUF4603 PF15376.6 KXL42594.1 - 0.23 8.8 4.1 0.34 8.2 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Methyltransf_11 PF08241.12 KXL42596.1 - 7.9e-17 61.7 0.1 1.3e-16 61.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL42596.1 - 6.4e-16 58.8 0.1 1.3e-15 57.8 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL42596.1 - 1.3e-09 38.7 0.0 3e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL42596.1 - 1.8e-08 34.3 0.0 3.7e-08 33.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXL42596.1 - 7.2e-08 32.4 0.0 1.2e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXL42596.1 - 9.2e-07 28.4 0.0 1.5e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXL42596.1 - 0.00013 21.6 0.0 0.00024 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 KXL42596.1 - 0.0019 17.8 0.0 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) DREV PF05219.12 KXL42596.1 - 0.0069 15.5 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_8 PF05148.15 KXL42596.1 - 0.013 15.4 0.0 0.025 14.4 0.0 1.5 1 1 0 1 1 1 0 Hypothetical methyltransferase FtsJ PF01728.19 KXL42596.1 - 0.016 15.3 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_29 PF03141.16 KXL42596.1 - 0.024 13.2 0.0 0.13 10.8 0.0 1.9 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.20 KXL42596.1 - 0.036 13.1 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.17 KXL42596.1 - 0.037 13.5 0.1 13 5.2 0.0 3.0 2 1 1 3 3 3 0 Putative methyltransferase DUF938 PF06080.12 KXL42596.1 - 0.042 13.6 0.0 0.18 11.5 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF938) LSM PF01423.22 KXL42597.1 - 6e-17 61.1 0.0 7.4e-17 60.8 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXL42597.1 - 0.00042 20.4 0.0 0.00053 20.1 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 KXL42597.1 - 0.0035 17.4 0.0 0.004 17.2 0.0 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain Hfq PF17209.3 KXL42597.1 - 0.18 11.5 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Hfq protein Rad60-SLD PF11976.8 KXL42598.1 - 2.4e-15 56.1 0.2 1.9e-14 53.2 0.1 2.4 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KXL42598.1 - 0.00048 19.8 0.0 0.0014 18.4 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family TUG-UBL1 PF11470.8 KXL42598.1 - 0.0031 17.7 0.0 0.017 15.3 0.0 2.0 2 0 0 2 2 2 1 TUG ubiquitin-like domain TFIIA PF03153.13 KXL42599.1 - 0.051 13.6 18.2 0.014 15.4 6.3 2.5 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 KXL42599.1 - 0.43 9.2 12.4 0.015 14.0 5.1 1.9 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup ERM PF00769.19 KXL42599.1 - 2.7 7.7 48.5 0.018 14.8 39.8 1.7 2 0 0 2 2 2 0 Ezrin/radixin/moesin family NUP50 PF08911.11 KXL42601.1 - 0.056 14.1 1.7 0.17 12.6 1.7 1.8 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) Cwf_Cwc_15 PF04889.12 KXL42601.1 - 0.079 12.7 8.8 0.14 11.9 8.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DnaJ PF00226.31 KXL42604.1 - 4.2e-20 71.6 1.5 4.9e-20 71.4 1.5 1.1 1 0 0 1 1 1 1 DnaJ domain Mt_ATP-synt_D PF05873.12 KXL42604.1 - 0.072 12.9 0.0 0.079 12.8 0.0 1.1 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Glyco_hydro_31 PF01055.26 KXL42605.1 - 1.6e-106 357.1 0.7 1.9e-106 356.9 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KXL42605.1 - 7.9e-17 61.4 0.1 2e-16 60.0 0.1 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like PAM2 PF07145.15 KXL42606.1 - 0.006 16.2 0.0 0.016 14.9 0.0 1.7 1 0 0 1 1 1 1 Ataxin-2 C-terminal region FAA_hydrolase PF01557.18 KXL42607.1 - 8.1e-60 202.2 0.0 1e-59 201.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family EPL1 PF10513.9 KXL42608.1 - 0.37 11.2 5.4 0.13 12.7 1.3 2.0 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF4396 PF14342.6 KXL42610.1 - 4.5e-37 127.5 13.9 4.5e-37 127.5 13.9 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4396) MFS_1 PF07690.16 KXL42610.1 - 4e-05 22.7 11.4 0.00012 21.2 11.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL42611.1 - 2e-13 50.0 2.8 2.2e-13 49.9 2.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Phage_holin_3_2 PF04550.12 KXL42611.1 - 0.11 13.0 1.1 0.19 12.3 1.1 1.3 1 0 0 1 1 1 0 Phage holin family 2 QCR10 PF09796.9 KXL42611.1 - 0.13 12.4 0.3 0.24 11.5 0.1 1.6 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) SWIB PF02201.18 KXL42612.1 - 9.3e-22 76.7 0.0 2e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain Amidohydro_3 PF07969.11 KXL42613.1 - 0.00076 19.1 1.1 0.087 12.3 0.0 2.6 1 1 1 2 2 2 2 Amidohydrolase family Tim54 PF11711.8 KXL42614.1 - 0.0099 14.7 2.2 0.018 13.8 2.2 1.4 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 RNase_H2_suC PF08615.11 KXL42614.1 - 0.037 14.2 0.0 0.077 13.2 0.0 1.7 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Nop14 PF04147.12 KXL42614.1 - 0.086 11.1 11.3 0.14 10.3 11.3 1.2 1 0 0 1 1 1 0 Nop14-like family NBD_C PF17042.5 KXL42614.1 - 0.092 13.2 0.2 0.22 12.0 0.2 1.6 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain Sporozoite_P67 PF05642.11 KXL42614.1 - 0.21 9.6 3.5 0.41 8.7 3.5 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Myc_N PF01056.18 KXL42614.1 - 2.3 8.0 8.7 8.2 6.2 8.7 1.9 1 0 0 1 1 1 0 Myc amino-terminal region RXT2_N PF08595.11 KXL42614.1 - 2.4 8.2 10.0 2.9 7.9 8.1 2.0 2 0 0 2 2 2 0 RXT2-like, N-terminal NOA36 PF06524.12 KXL42614.1 - 2.6 7.3 14.4 4.3 6.6 14.4 1.2 1 0 0 1 1 1 0 NOA36 protein TRAP_alpha PF03896.16 KXL42614.1 - 2.9 7.0 8.9 5.7 6.1 8.9 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Folate_carrier PF01770.18 KXL42614.1 - 3.2 6.4 3.7 4.6 5.9 3.7 1.1 1 0 0 1 1 1 0 Reduced folate carrier Radial_spoke PF04712.12 KXL42614.1 - 3.2 6.6 16.7 5.9 5.7 16.7 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein DUF4746 PF15928.5 KXL42614.1 - 3.5 7.0 14.5 7.9 5.8 14.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RAB3GAP2_C PF14656.6 KXL42614.1 - 3.8 5.6 5.6 5.5 5.1 5.6 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus RPA43_OB PF17875.1 KXL42614.1 - 4.9 7.8 6.6 16 6.1 6.6 1.9 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I CDC45 PF02724.14 KXL42614.1 - 5.3 5.2 12.5 8.4 4.5 12.5 1.2 1 0 0 1 1 1 0 CDC45-like protein HSP90 PF00183.18 KXL42614.1 - 8.9 5.1 14.7 6.7 5.5 13.0 1.5 2 0 0 2 2 2 0 Hsp90 protein adh_short PF00106.25 KXL42615.1 - 6.9e-26 90.9 0.0 2.8e-23 82.4 0.0 2.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL42615.1 - 1.1e-16 61.1 0.1 4.5e-08 32.9 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL42615.1 - 1.3e-07 31.7 0.4 1.4e-05 25.1 0.4 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL42615.1 - 0.0095 15.4 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXL42615.1 - 0.03 13.3 0.0 0.043 12.8 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1580 PF07618.11 KXL42616.1 - 0.33 10.6 1.6 0.98 9.1 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1580) Pkinase PF00069.25 KXL42617.1 - 7.1e-64 215.7 0.0 9.7e-64 215.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL42617.1 - 4e-31 108.2 0.0 4.2e-29 101.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXL42617.1 - 0.00017 21.0 0.2 0.0019 17.6 0.0 2.3 3 0 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 KXL42617.1 - 0.0012 17.9 0.0 0.0017 17.3 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KXL42617.1 - 0.0013 18.1 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXL42617.1 - 0.004 17.1 0.0 0.0068 16.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KXL42617.1 - 0.018 14.7 0.1 2.1 7.9 0.0 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 TRAM_LAG1_CLN8 PF03798.16 KXL42618.1 - 2e-46 158.3 15.0 2e-46 158.3 15.0 1.6 2 0 0 2 2 2 1 TLC domain DUF4870 PF09685.10 KXL42618.1 - 0.51 10.5 4.9 1.1 9.4 1.7 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4870) Bac_rhamnosid6H PF17389.2 KXL42619.1 - 6.9e-11 42.0 0.1 1.2e-10 41.1 0.1 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Trehalase PF01204.18 KXL42619.1 - 0.0088 14.9 0.3 0.014 14.3 0.3 1.2 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.14 KXL42619.1 - 0.028 13.4 0.3 0.096 11.6 0.3 1.7 1 1 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Bac_rhamnosid_C PF17390.2 KXL42619.1 - 0.063 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase C-terminal domain Cpn60_TCP1 PF00118.24 KXL42620.1 - 1.5e-163 545.0 3.6 1.7e-163 544.8 3.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family BRK PF07533.16 KXL42620.1 - 0.18 11.5 0.0 0.35 10.5 0.0 1.5 1 0 0 1 1 1 0 BRK domain Glyco_hydro_35 PF01301.19 KXL42621.1 - 3.9e-87 292.8 0.5 6.4e-87 292.1 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KXL42621.1 - 1.1e-49 167.7 7.5 1.1e-27 96.8 0.0 4.0 4 0 0 4 4 4 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KXL42621.1 - 4.1e-46 157.1 0.6 6.6e-46 156.4 0.6 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KXL42621.1 - 1.8e-19 69.1 0.6 4e-18 64.8 0.1 2.7 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 KXL42621.1 - 0.002 17.6 0.2 0.0043 16.5 0.2 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) VPR PF00522.18 KXL42621.1 - 0.11 12.5 0.6 0.83 9.7 0.1 2.2 2 0 0 2 2 2 0 VPR/VPX protein ABC2_membrane PF01061.24 KXL42622.1 - 1.4e-79 266.4 59.7 1.1e-41 142.6 32.1 3.4 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KXL42622.1 - 4.1e-37 127.8 0.0 1.1e-18 68.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KXL42622.1 - 1.5e-24 85.7 23.1 7.1e-24 83.5 0.1 4.1 4 0 0 4 4 4 2 CDR ABC transporter ABC_trans_N PF14510.6 KXL42622.1 - 1.5e-17 64.0 0.7 5.1e-17 62.2 0.7 2.0 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 KXL42622.1 - 1.9e-06 27.9 0.1 0.00026 20.9 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KXL42622.1 - 1.4e-05 25.6 0.1 0.0044 17.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KXL42622.1 - 3.2e-05 23.9 0.1 0.033 14.0 0.0 2.5 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KXL42622.1 - 7.5e-05 22.8 0.2 0.092 12.8 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 KXL42622.1 - 0.00018 21.8 0.4 0.0043 17.3 0.1 3.0 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 KXL42622.1 - 0.00028 20.5 0.2 0.43 10.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 KXL42622.1 - 0.00034 21.2 0.0 0.021 15.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXL42622.1 - 0.0044 17.3 0.2 0.64 10.3 0.1 2.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KXL42622.1 - 0.0079 15.8 0.1 0.28 10.8 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KXL42622.1 - 0.0082 16.3 0.0 0.2 11.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KXL42622.1 - 0.014 15.1 0.5 0.47 10.1 0.1 2.9 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 KXL42622.1 - 0.029 14.3 0.2 1.3 8.9 0.2 2.3 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 KXL42622.1 - 0.032 13.8 0.2 0.41 10.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KXL42622.1 - 0.033 13.9 1.2 2.7 7.7 0.4 2.5 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 KXL42622.1 - 0.034 13.6 1.0 0.22 10.9 0.0 2.6 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.23 KXL42622.1 - 0.052 13.6 0.1 0.55 10.3 0.0 2.8 3 0 0 3 3 3 0 Dynamin family TsaE PF02367.17 KXL42622.1 - 0.072 13.1 0.9 1.8 8.6 0.3 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 KXL42622.1 - 0.088 12.0 0.2 2.7 7.1 0.2 2.4 2 0 0 2 2 2 0 NB-ARC domain Septin PF00735.18 KXL42622.1 - 0.089 12.1 0.1 0.46 9.7 0.2 1.9 2 0 0 2 2 2 0 Septin GBP PF02263.19 KXL42622.1 - 0.15 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain PduV-EutP PF10662.9 KXL42622.1 - 0.17 11.6 0.3 0.47 10.2 0.2 1.7 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.18 KXL42622.1 - 0.2 11.0 0.3 7.4 5.8 0.2 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Cnn_1N PF07989.11 KXL42624.1 - 4.9e-07 29.8 9.8 1.2e-06 28.6 9.8 1.6 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 Herpes_UL25 PF01499.16 KXL42624.1 - 0.013 14.1 1.4 0.023 13.2 1.4 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family FlxA PF14282.6 KXL42624.1 - 0.092 12.7 2.8 0.36 10.8 2.8 2.0 1 0 0 1 1 1 0 FlxA-like protein KASH_CCD PF14662.6 KXL42624.1 - 0.12 12.2 9.2 0.23 11.3 9.2 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Lectin_N PF03954.14 KXL42624.1 - 0.35 10.6 2.8 1.1 9.0 2.8 1.8 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Csm1_N PF18504.1 KXL42624.1 - 1.3 9.4 10.1 2.7 8.4 5.3 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Cupin_8 PF13621.6 KXL42625.1 - 1.5e-39 136.3 0.0 2.3e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KXL42625.1 - 6e-07 29.2 0.0 5.1e-05 22.9 0.0 2.6 3 0 0 3 3 3 1 Cupin superfamily protein JmjC PF02373.22 KXL42625.1 - 0.026 14.9 0.0 0.25 11.8 0.0 2.2 2 0 0 2 2 2 0 JmjC domain, hydroxylase Cupin_2 PF07883.11 KXL42625.1 - 0.2 11.4 0.0 0.62 9.8 0.0 1.8 2 0 0 2 2 2 0 Cupin domain SLX9 PF15341.6 KXL42626.1 - 2.3e-28 99.2 1.7 3.8e-28 98.5 1.7 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 DUF5549 PF17703.1 KXL42626.1 - 1.4 8.6 4.8 2.5 7.7 4.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5549) ADH_N PF08240.12 KXL42627.1 - 1.3e-31 108.7 0.3 2.6e-31 107.8 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXL42627.1 - 4.4e-17 62.3 0.0 6.7e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXL42627.1 - 1.2e-06 28.1 0.0 2.5e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KXL42627.1 - 5.4e-05 22.6 0.0 8.5e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KXL42627.1 - 0.00051 21.1 0.0 0.0012 19.8 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Fer4_10 PF13237.6 KXL42627.1 - 0.024 14.7 0.8 1.2 9.3 0.1 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain Phage_SSB PF16773.5 KXL42627.1 - 0.15 12.2 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 Lactococcus phage single-stranded DNA binding protein RPN7 PF10602.9 KXL42628.1 - 7.3e-23 81.2 0.7 2.9e-11 43.4 0.0 3.2 2 1 0 2 2 2 2 26S proteasome subunit RPN7 PCI PF01399.27 KXL42628.1 - 5.9e-07 30.0 0.0 1.1e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 PCI domain AhpC-TSA_2 PF13911.6 KXL42629.1 - 1.1e-17 64.1 0.0 1.7e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KXL42629.1 - 0.00091 19.1 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXL42629.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Redoxin Fez1 PF06818.15 KXL42631.1 - 0.033 14.7 0.1 0.043 14.3 0.1 1.2 1 0 0 1 1 1 0 Fez1 Pkinase PF00069.25 KXL42632.1 - 1.1e-06 28.2 0.4 2.2e-06 27.3 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 KXL42632.1 - 1.4e-06 27.8 0.0 3.3e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Radial_spoke_3 PF06098.11 KXL42632.1 - 8.5e-05 22.0 10.6 0.00017 21.0 10.6 1.5 1 0 0 1 1 1 1 Radial spoke protein 3 Choline_kinase PF01633.20 KXL42632.1 - 0.00013 21.6 0.0 0.00032 20.3 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase G0-G1_switch_2 PF15103.6 KXL42632.1 - 0.00043 20.7 3.5 0.0011 19.4 3.5 1.7 1 0 0 1 1 1 1 G0/G1 switch protein 2 APH PF01636.23 KXL42632.1 - 0.0005 20.1 0.0 0.0005 20.1 0.0 3.3 3 1 1 4 4 4 1 Phosphotransferase enzyme family DUF913 PF06025.12 KXL42632.1 - 0.033 13.2 0.1 0.057 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Kinase-like PF14531.6 KXL42632.1 - 0.037 13.3 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 KXL42632.1 - 0.071 12.7 0.0 0.071 12.7 0.0 2.0 2 0 0 2 2 1 0 RIO1 family MIF4G_like_2 PF09090.11 KXL42632.1 - 0.087 12.3 4.9 0.18 11.2 4.9 1.4 1 0 0 1 1 1 0 MIF4G like CPSF100_C PF13299.6 KXL42632.1 - 0.14 12.3 5.4 0.34 11.1 5.4 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DNA_pol_phi PF04931.13 KXL42632.1 - 0.21 9.6 4.6 0.33 9.0 4.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi AAA_11 PF13086.6 KXL42632.1 - 0.23 11.2 4.1 0.45 10.3 4.1 1.4 1 0 0 1 1 1 0 AAA domain Connexin PF00029.19 KXL42632.1 - 0.31 10.7 3.7 0.52 10.0 3.7 1.2 1 0 0 1 1 1 0 Connexin DUF4407 PF14362.6 KXL42632.1 - 0.32 10.3 4.7 0.64 9.3 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) eIF3_subunit PF08597.10 KXL42632.1 - 0.4 10.5 12.4 0.8 9.6 12.4 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit FemAB PF02388.16 KXL42632.1 - 0.57 9.0 6.3 0.93 8.3 6.3 1.2 1 0 0 1 1 1 0 FemAB family PPL5 PF18168.1 KXL42632.1 - 0.59 9.4 3.2 0.99 8.6 3.2 1.2 1 0 0 1 1 1 0 Prim-pol family 5 NARP1 PF12569.8 KXL42632.1 - 0.95 8.3 8.9 1.5 7.6 8.9 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Ctr PF04145.15 KXL42632.1 - 1 10.0 2.5 7.8 7.1 1.0 2.4 2 0 0 2 2 2 0 Ctr copper transporter family U79_P34 PF03064.16 KXL42632.1 - 1.1 8.6 10.9 2 7.7 10.9 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DDRGK PF09756.9 KXL42632.1 - 1.7 8.2 24.3 3.1 7.3 24.3 1.3 1 0 0 1 1 1 0 DDRGK domain Macoilin PF09726.9 KXL42632.1 - 3 6.3 13.4 4.6 5.7 13.4 1.2 1 0 0 1 1 1 0 Macoilin family DUF2828 PF11443.8 KXL42632.1 - 4.4 5.3 10.2 8.2 4.4 10.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF4192 PF13830.6 KXL42632.1 - 7.7 6.5 20.1 4.4 7.3 11.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4192) Presenilin PF01080.17 KXL42632.1 - 9.1 4.9 8.7 15 4.2 8.7 1.2 1 0 0 1 1 1 0 Presenilin DUF725 PF05267.12 KXL42634.1 - 0.072 13.1 3.2 0.078 13.0 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF725) PEP-utilisers_N PF05524.13 KXL42634.1 - 0.13 12.5 8.9 0.17 12.1 8.9 1.3 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal DUF883 PF05957.13 KXL42634.1 - 1 10.0 10.2 1.1 9.9 10.2 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) ATP-synt_B PF00430.18 KXL42634.1 - 1.6 8.8 17.3 1.7 8.7 17.3 1.0 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) KfrA_N PF11740.8 KXL42634.1 - 2 9.1 13.9 2.1 9.0 13.9 1.1 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term DUF3987 PF13148.6 KXL42634.1 - 4.2 6.3 13.8 4.3 6.3 13.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) GrpE PF01025.19 KXL42634.1 - 5.7 6.6 12.3 5.9 6.5 12.3 1.0 1 0 0 1 1 1 0 GrpE DUF2229 PF09989.9 KXL42634.1 - 9.1 5.9 8.4 11 5.6 8.4 1.1 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) DDE_1 PF03184.19 KXL42635.1 - 0.0005 19.8 0.0 0.00075 19.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2046 PF09755.9 KXL42635.1 - 0.0085 15.4 0.6 0.013 14.8 0.4 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) EMP70 PF02990.16 KXL42636.1 - 1.6e-200 667.2 0.2 2.1e-200 666.8 0.2 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 NMT1 PF09084.11 KXL42638.1 - 0.00024 21.1 0.0 0.0023 17.9 0.0 2.1 2 0 0 2 2 2 1 NMT1/THI5 like VitK2_biosynth PF02621.14 KXL42638.1 - 0.0028 17.2 0.0 0.032 13.7 0.0 2.1 2 0 0 2 2 2 1 Menaquinone biosynthesis SBP_bac_3 PF00497.20 KXL42638.1 - 0.0036 16.8 0.0 0.0066 15.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 KXL42638.1 - 0.04 13.5 0.0 0.059 13.0 0.0 1.2 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Sugar_tr PF00083.24 KXL42639.1 - 2e-83 280.8 25.5 2.3e-83 280.6 25.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL42639.1 - 7.5e-19 67.9 55.5 5.1e-15 55.3 29.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 KXL42639.1 - 0.0066 14.8 1.1 0.011 14.1 1.1 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) ABC2_membrane_2 PF12679.7 KXL42639.1 - 1.4 8.1 10.2 0.12 11.6 5.3 1.7 2 0 0 2 2 2 0 ABC-2 family transporter protein SRPRB PF09439.10 KXL42640.1 - 1.3e-30 106.2 0.0 5.5e-30 104.1 0.0 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 KXL42640.1 - 3.3e-06 26.7 0.0 0.00039 19.9 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXL42640.1 - 7.7e-06 26.0 0.0 1.2e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KXL42640.1 - 1.5e-05 25.5 0.1 2.6e-05 24.7 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXL42640.1 - 0.00014 22.2 0.0 0.0003 21.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KXL42640.1 - 0.001 19.0 0.1 0.0063 16.4 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA PF00004.29 KXL42640.1 - 0.0013 19.1 0.0 0.0022 18.4 0.0 1.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 KXL42640.1 - 0.0026 17.9 0.1 0.017 15.4 0.0 2.4 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 KXL42640.1 - 0.0047 17.5 0.0 0.009 16.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ATP_bind_1 PF03029.17 KXL42640.1 - 0.0069 16.2 0.0 0.44 10.3 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 KXL42640.1 - 0.0084 16.6 0.0 0.014 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 KXL42640.1 - 0.0093 15.4 0.0 0.033 13.6 0.0 1.7 2 0 0 2 2 2 1 Bacterial TniB protein TsaE PF02367.17 KXL42640.1 - 0.011 15.7 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 KXL42640.1 - 0.015 14.9 0.4 0.68 9.5 0.3 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 KXL42640.1 - 0.02 14.9 0.0 0.047 13.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 KXL42640.1 - 0.029 14.1 0.0 0.073 12.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KXL42640.1 - 0.046 13.0 0.0 0.089 12.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Gtr1_RagA PF04670.12 KXL42640.1 - 0.082 12.2 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 KXL42640.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SRP54 PF00448.22 KXL42640.1 - 0.13 11.9 0.0 0.99 9.0 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain VIT1 PF01988.19 KXL42641.1 - 2.1e-70 237.0 0.2 2.3e-70 236.8 0.2 1.0 1 0 0 1 1 1 1 VIT family OST3_OST6 PF04756.13 KXL42641.1 - 0.24 10.7 1.8 0.35 10.2 1.8 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Sugar_tr PF00083.24 KXL42642.1 - 9.5e-79 265.4 20.0 1.1e-78 265.2 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL42642.1 - 3.7e-33 114.9 48.9 5.4e-29 101.2 27.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXL42642.1 - 0.64 8.2 13.2 0.17 10.1 5.4 2.3 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family NPR2 PF06218.11 KXL42643.1 - 4.1e-94 315.8 0.0 8.6e-93 311.5 0.0 2.0 1 1 0 1 1 1 1 Nitrogen permease regulator 2 NPR3 PF03666.13 KXL42643.1 - 0.015 14.2 0.3 0.042 12.6 0.2 1.7 2 1 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 RGS PF00615.19 KXL42644.1 - 3.1e-12 46.8 0.0 1.7e-09 37.9 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain Glyco_trans_1_4 PF13692.6 KXL42647.1 - 4.4e-10 40.1 0.0 5.3e-08 33.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KXL42647.1 - 4.6e-06 26.3 0.0 9.1e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KXL42647.1 - 0.0022 18.3 0.0 0.0053 17.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Cation_efflux PF01545.21 KXL42648.1 - 6.7e-44 150.0 4.4 6.7e-44 150.0 4.4 2.7 3 0 0 3 3 3 1 Cation efflux family Sugar_tr PF00083.24 KXL42649.1 - 2.2e-95 320.2 15.3 2.6e-95 320.0 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL42649.1 - 6.5e-30 104.2 55.0 8.6e-29 100.6 30.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3040 PF11239.8 KXL42649.1 - 0.85 9.9 3.6 8 6.8 1.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) HTH_psq PF05225.16 KXL42650.1 - 0.0023 17.6 0.9 0.0058 16.4 0.2 1.9 2 0 0 2 2 2 1 helix-turn-helix, Psq domain F_bP_aldolase PF01116.20 KXL42652.1 - 2.6e-75 253.5 1.0 3e-75 253.3 1.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Zn_clus PF00172.18 KXL42654.1 - 0.0049 17.0 8.1 0.011 15.9 8.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 KXL42654.1 - 0.3 11.0 14.6 0.48 10.4 14.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit M_domain PF12938.7 KXL42654.1 - 1.5 8.5 19.3 3.7 7.3 19.3 1.6 1 0 0 1 1 1 0 M domain of GW182 AA_permease_2 PF13520.6 KXL42656.1 - 4e-52 177.5 47.0 5e-52 177.2 47.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXL42656.1 - 2.2e-23 82.6 37.9 2.9e-23 82.2 37.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4112 PF13430.6 KXL42656.1 - 0.094 13.0 3.6 0.096 13.0 1.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4112) DEAD PF00270.29 KXL42657.1 - 6.9e-43 146.4 0.1 1.2e-42 145.6 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXL42657.1 - 1.7e-21 76.6 0.0 8.5e-21 74.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL42657.1 - 1.3e-05 25.2 0.0 2.3e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KXL42657.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase SecA_DEAD PF07517.14 KXL42657.1 - 0.13 11.5 0.1 0.23 10.7 0.1 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain GFO_IDH_MocA PF01408.22 KXL42658.1 - 7.2e-16 59.1 0.3 1.9e-15 57.8 0.1 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Fanconi_A PF03511.14 KXL42658.1 - 0.19 11.7 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 Fanconi anaemia group A protein MFS_1 PF07690.16 KXL42659.1 - 2e-26 92.8 21.6 2e-26 92.8 21.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXL42659.1 - 0.00091 17.8 4.1 0.00091 17.8 4.1 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OPT PF03169.15 KXL42660.1 - 1.2e-148 496.5 49.9 1.3e-148 496.4 49.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Otopetrin PF03189.13 KXL42661.1 - 0.026 13.3 0.0 0.033 13.0 0.0 1.1 1 0 0 1 1 1 0 Otopetrin Phage_Gp23 PF10669.9 KXL42661.1 - 0.2 12.0 3.3 0.29 11.5 2.8 1.6 1 1 0 1 1 1 0 Protein gp23 (Bacteriophage A118) MAP17 PF15807.5 KXL42661.1 - 0.39 10.9 4.4 0.12 12.7 0.6 1.8 1 1 1 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Peptidase_S15 PF02129.18 KXL42661.1 - 0.5 9.9 3.3 0.51 9.9 2.6 1.4 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) G0-G1_switch_2 PF15103.6 KXL42661.1 - 1.7 9.1 5.1 3.1 8.3 4.5 1.8 1 1 1 2 2 2 0 G0/G1 switch protein 2 Sedlin_N PF04628.13 KXL42662.1 - 1.7e-38 131.7 0.0 3.7e-38 130.6 0.0 1.5 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KXL42662.1 - 0.00031 20.7 0.0 0.012 15.6 0.0 2.1 2 0 0 2 2 2 2 Sybindin-like family L31 PF09784.9 KXL42663.1 - 9.9e-42 141.5 0.7 1.1e-23 83.6 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial ribosomal protein L31 RINGv PF12906.7 KXL42664.1 - 3.6e-17 62.2 8.4 7.6e-17 61.2 8.4 1.6 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KXL42664.1 - 0.0013 19.0 9.1 0.004 17.4 9.1 1.9 1 0 0 1 1 1 1 Ring finger domain CPL PF08144.11 KXL42664.1 - 0.025 14.9 0.3 0.66 10.3 0.0 2.4 2 0 0 2 2 2 0 CPL (NUC119) domain zf-ANAPC11 PF12861.7 KXL42664.1 - 0.044 13.8 2.8 0.12 12.5 2.8 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rsm22 PF09243.10 KXL42664.1 - 0.14 11.4 0.4 0.38 10.0 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial small ribosomal subunit Rsm22 DLP_helical PF18709.1 KXL42664.1 - 0.24 10.6 5.0 0.36 10.0 5.0 1.2 1 0 0 1 1 1 0 Dynamin-like helical domain zf-C3HC4_3 PF13920.6 KXL42664.1 - 0.65 9.9 5.7 1.5 8.8 5.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KXL42664.1 - 0.69 9.7 7.9 1.6 8.5 7.9 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF745 PF05335.13 KXL42664.1 - 2.4 7.9 4.1 5.6 6.7 4.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF745) FANCL_C PF11793.8 KXL42664.1 - 8.2 6.7 6.6 19 5.5 6.6 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain Apolipoprotein PF01442.18 KXL42665.1 - 0.00066 19.6 43.0 0.41 10.5 4.5 8.6 7 4 1 8 8 8 6 Apolipoprotein A1/A4/E domain DUF842 PF05811.13 KXL42665.1 - 0.2 11.4 1.7 7.9 6.2 0.3 4.2 4 0 0 4 4 4 0 Eukaryotic protein of unknown function (DUF842) BshC PF10079.9 KXL42665.1 - 0.28 9.9 2.3 0.43 9.3 0.4 2.3 2 0 0 2 2 2 0 Bacillithiol biosynthesis BshC DUF148 PF02520.17 KXL42665.1 - 0.49 10.5 6.1 0.2 11.8 0.3 3.6 3 0 0 3 3 3 0 Domain of unknown function DUF148 CDC37_N PF03234.14 KXL42667.1 - 1.9e-47 161.4 0.8 1.9e-47 161.4 0.8 2.6 4 0 0 4 4 4 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 KXL42667.1 - 3e-41 140.0 0.3 6.2e-41 139.0 0.3 1.5 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 KXL42667.1 - 2.7e-29 101.2 0.8 1.2e-28 99.1 0.1 2.4 2 0 0 2 2 2 1 Cdc37 C terminal domain YkuD_2 PF13645.6 KXL42669.1 - 0.2 11.1 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain Actin PF00022.19 KXL42670.1 - 3.2e-81 273.0 0.0 1.5e-79 267.5 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KXL42670.1 - 0.16 10.8 0.0 0.71 8.6 0.0 2.0 3 0 0 3 3 3 0 MreB/Mbl protein FtsA PF14450.6 KXL42670.1 - 0.16 12.4 0.0 0.33 11.4 0.0 1.5 1 1 0 1 1 1 0 Cell division protein FtsA GCIP PF13324.6 KXL42671.1 - 2.8e-36 125.5 0.0 3.3e-36 125.2 0.0 1.0 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting SinI PF08671.10 KXL42671.1 - 9.9 6.1 8.1 28 4.6 1.0 2.7 2 0 0 2 2 2 0 Anti-repressor SinI DUF1729 PF08354.10 KXL42672.1 - 4.9e-163 542.1 0.0 8e-163 541.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 KXL42672.1 - 1.8e-87 293.8 0.0 5.1e-87 292.3 0.0 1.8 1 0 0 1 1 1 1 Acyl transferase domain FAS_meander PF17951.1 KXL42672.1 - 2.2e-53 180.0 0.0 4.8e-53 178.9 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 KXL42672.1 - 1.8e-38 132.6 0.0 3.9e-38 131.5 0.0 1.6 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 KXL42672.1 - 8e-36 122.3 0.2 3.1e-35 120.4 0.0 2.1 2 0 0 2 2 2 1 MaoC like domain FAS_N PF17828.1 KXL42672.1 - 3e-33 114.6 0.0 6.4e-33 113.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydrat_N PF13452.6 KXL42672.1 - 4.3e-23 81.9 0.0 1.5e-22 80.1 0.0 2.0 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.15 KXL42672.1 - 0.0016 17.9 0.1 0.027 13.9 0.1 2.5 1 1 0 1 1 1 1 Nitronate monooxygenase IKBKB_SDD PF18397.1 KXL42672.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 IQBAL scaffold dimerization domain FAS_I_H PF18314.1 KXL42673.1 - 9e-80 267.1 0.0 2.4e-79 265.7 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 KXL42673.1 - 2.5e-77 258.8 0.0 5.1e-77 257.8 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 KXL42673.1 - 3.5e-21 75.9 0.0 7.7e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 KXL42673.1 - 1.9e-13 50.5 0.0 4.8e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 KXL42673.1 - 1e-10 41.6 0.0 3e-10 40.2 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 KXL42673.1 - 0.0024 17.8 0.0 0.0078 16.1 0.0 1.8 1 0 0 1 1 1 1 KR domain PnpCD_PnpD_N PF18191.1 KXL42673.1 - 0.076 12.6 0.0 0.23 11.1 0.0 1.8 1 0 0 1 1 1 0 Hydroquinone 1,2-dioxygenase large subunit N-terminal PAP_assoc PF03828.19 KXL42674.1 - 1.4e-10 41.2 0.0 3.4e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KXL42674.1 - 2.1e-08 34.3 0.0 6.4e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Pinin_SDK_N PF04697.13 KXL42676.1 - 3.7 8.2 7.1 28 5.4 0.3 3.7 3 0 0 3 3 3 0 pinin/SDK conserved region DPM3 PF08285.11 KXL42677.1 - 1.2e-36 124.8 0.0 1.3e-36 124.6 0.0 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) ComZ PF10815.8 KXL42677.1 - 0.012 15.5 0.0 3.6 7.7 0.0 2.7 2 1 1 3 3 3 0 ComZ UNC45-central PF11701.8 KXL42678.1 - 0.0089 16.0 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central SNF2_N PF00176.23 KXL42679.1 - 2.1e-75 253.7 0.1 5.5e-75 252.3 0.1 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 KXL42679.1 - 2.3e-42 143.6 8.6 5.3e-42 142.5 2.3 3.2 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 KXL42679.1 - 1.8e-34 118.8 4.1 1.8e-34 118.8 4.1 3.2 3 0 0 3 3 3 1 HAND Helicase_C PF00271.31 KXL42679.1 - 3.3e-19 69.3 0.1 2.7e-18 66.3 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL42679.1 - 2.5e-10 40.6 0.3 1.4e-09 38.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KXL42679.1 - 4.1e-05 22.9 0.7 0.00017 20.8 0.1 2.3 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Myb_DNA-binding PF00249.31 KXL42679.1 - 5.9e-05 23.2 0.0 0.04 14.1 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain DEAD PF00270.29 KXL42679.1 - 0.00033 20.5 0.0 0.00085 19.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KXL42679.1 - 0.0009 19.0 1.8 0.005 16.5 0.0 2.8 3 0 0 3 3 3 1 SWI2/SNF2 ATPase AAA_14 PF13173.6 KXL42679.1 - 0.044 13.8 0.1 0.21 11.6 0.1 2.2 1 0 0 1 1 1 0 AAA domain DEAD_2 PF06733.15 KXL42679.1 - 0.051 13.2 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 DEAD_2 AAA_22 PF13401.6 KXL42679.1 - 0.095 13.0 2.8 1 9.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain PCRF PF03462.18 KXL42680.1 - 1.6e-50 171.7 0.2 8.2e-50 169.4 0.0 2.1 2 1 1 3 3 3 1 PCRF domain RF-1 PF00472.20 KXL42680.1 - 5.5e-34 116.6 2.2 5.5e-34 116.6 2.2 2.3 3 0 0 3 3 3 1 RF-1 domain Tup_N PF08581.10 KXL42680.1 - 0.21 11.9 3.5 0.4 11.0 0.2 2.4 2 0 0 2 2 2 0 Tup N-terminal OmpH PF03938.14 KXL42680.1 - 0.75 10.1 3.7 2.7 8.3 0.3 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) TMF_TATA_bd PF12325.8 KXL42680.1 - 3.8 7.8 9.5 3.2 8.0 1.0 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding UQ_con PF00179.26 KXL42681.1 - 7.1e-39 132.7 0.0 9.2e-39 132.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXL42681.1 - 0.089 12.5 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B Fungal_trans PF04082.18 KXL42682.1 - 4.3e-14 52.2 3.0 1.4e-13 50.5 3.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KXL42682.1 - 0.00034 20.9 10.9 0.0064 16.9 0.3 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KXL42682.1 - 0.02 14.9 0.9 7.2 6.7 0.0 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KXL42682.1 - 3.7 8.6 9.1 1.2 10.2 0.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger FYVE PF01363.21 KXL42683.1 - 0.0025 17.9 6.3 0.0025 17.9 6.3 3.2 3 0 0 3 3 3 1 FYVE zinc finger zf-piccolo PF05715.13 KXL42683.1 - 8.2 6.7 12.3 1.4 9.1 2.7 3.1 3 0 0 3 3 3 0 Piccolo Zn-finger Pkinase PF00069.25 KXL42685.1 - 4.6e-26 91.7 0.0 6.6e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL42685.1 - 5.2e-13 48.9 0.0 7.1e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Rotamase_3 PF13616.6 KXL42685.1 - 0.12 12.9 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 PPIC-type PPIASE domain C2 PF00168.30 KXL42686.1 - 3.6e-16 59.3 0.0 9.9e-16 57.9 0.0 1.8 2 0 0 2 2 2 1 C2 domain Laminin_G_1 PF00054.23 KXL42687.1 - 0.044 14.0 0.0 0.13 12.5 0.0 1.7 1 1 1 2 2 2 0 Laminin G domain DUF3992 PF13157.6 KXL42687.1 - 0.12 13.2 3.4 1.3 9.8 0.1 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF3992) DUF4046 PF13255.6 KXL42689.1 - 0.084 13.4 0.1 0.23 12.0 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4046) LRR_3 PF07725.12 KXL42689.1 - 0.36 10.8 2.5 2.7 8.0 2.5 2.1 1 1 0 1 1 1 0 Leucine Rich Repeat Vps51 PF08700.11 KXL42691.1 - 7.3e-11 42.0 0.0 3.7e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 Vps51/Vps67 WXG100 PF06013.12 KXL42691.1 - 0.16 12.2 0.6 1.4 9.2 0.0 2.9 4 0 0 4 4 4 0 Proteins of 100 residues with WXG HBM PF16591.5 KXL42691.1 - 0.26 10.7 3.1 0.51 9.7 2.1 1.9 2 0 0 2 2 2 0 Helical bimodular sensor domain Apolipoprotein PF01442.18 KXL42691.1 - 0.44 10.4 6.0 11 5.9 0.1 3.5 4 0 0 4 4 4 0 Apolipoprotein A1/A4/E domain HET PF06985.11 KXL42692.1 - 2.4e-21 76.6 0.0 4.9e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ANAPC4_WD40 PF12894.7 KXL42693.1 - 7.1e-05 23.0 0.0 0.19 12.0 0.0 4.7 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KXL42693.1 - 0.00026 21.0 0.0 0.00067 19.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain WD40 PF00400.32 KXL42693.1 - 0.00031 21.5 3.2 0.0089 16.9 0.1 4.6 4 0 0 4 4 4 1 WD domain, G-beta repeat Abhydrolase_6 PF12697.7 KXL42693.1 - 0.00032 21.4 0.2 0.0015 19.1 0.1 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family AAA_16 PF13191.6 KXL42693.1 - 0.0015 18.9 0.0 0.0047 17.3 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXL42693.1 - 0.0023 18.2 0.0 0.0057 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KXL42693.1 - 0.0042 17.4 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase DUF676 PF05057.14 KXL42693.1 - 0.026 14.0 0.1 0.053 13.0 0.1 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) APS_kinase PF01583.20 KXL42693.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Torsin PF06309.11 KXL42693.1 - 0.078 13.1 0.0 0.28 11.3 0.0 1.9 2 0 0 2 2 2 0 Torsin PAP2 PF01569.21 KXL42694.1 - 1.9e-11 43.9 4.8 6.7e-11 42.1 4.8 1.9 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 KXL42694.1 - 0.079 13.1 0.0 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 Divergent PAP2 family GtrA PF04138.14 KXL42694.1 - 0.63 10.3 5.8 0.65 10.2 2.6 2.0 2 0 0 2 2 2 0 GtrA-like protein Suc_Fer-like PF06999.12 KXL42695.1 - 1.1e-56 191.8 0.0 1.4e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Methyltransf_11 PF08241.12 KXL42696.1 - 5.2e-13 49.5 0.0 7.6e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL42696.1 - 3e-11 43.9 0.0 5e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXL42696.1 - 3.7e-11 43.1 0.0 1.8e-10 40.9 0.0 1.8 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL42696.1 - 1.3e-07 32.2 0.0 2.5e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL42696.1 - 7.2e-07 29.1 0.0 1.1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KXL42696.1 - 0.13 11.4 0.0 0.27 10.4 0.0 1.4 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family TehB PF03848.14 KXL42696.1 - 0.16 11.4 0.0 0.36 10.2 0.0 1.5 1 1 0 1 1 1 0 Tellurite resistance protein TehB Pkinase PF00069.25 KXL42697.1 - 6.8e-52 176.4 0.0 9.8e-52 175.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL42697.1 - 2.3e-29 102.5 0.0 3.5e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXL42697.1 - 3.3e-11 43.0 0.0 3.1e-09 36.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KXL42697.1 - 0.0082 15.5 0.0 0.019 14.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXL42697.1 - 0.037 13.9 0.0 0.085 12.8 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF918 PF06033.11 KXL42697.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF918) GMC_oxred_C PF05199.13 KXL42698.1 - 0.017 15.7 0.0 0.024 15.1 0.0 1.2 1 0 0 1 1 1 0 GMC oxidoreductase HAD_2 PF13419.6 KXL42699.1 - 8.1e-06 26.0 0.0 0.17 12.0 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXL42699.1 - 0.0058 16.9 0.0 0.11 12.7 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase 5-nucleotidase PF06189.12 KXL42699.1 - 0.03 13.3 0.0 0.047 12.6 0.0 1.2 1 0 0 1 1 1 0 5'-nucleotidase HAD PF12710.7 KXL42699.1 - 0.071 13.5 0.0 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Nexin_C PF08628.12 KXL42699.1 - 0.1 13.1 0.0 0.27 11.8 0.0 1.7 1 1 0 1 1 1 0 Sorting nexin C terminal 7TM_GPCR_Srt PF10321.9 KXL42700.1 - 0.0098 14.9 0.4 0.014 14.4 0.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srt DHHC PF01529.20 KXL42700.1 - 0.28 11.3 0.8 0.61 10.2 0.8 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase OppC_N PF12911.7 KXL42700.1 - 0.3 11.1 4.2 0.6 10.1 0.1 3.0 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C DUF2569 PF10754.9 KXL42700.1 - 1.8 9.0 9.0 2.1 8.8 7.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2569) Sec16_C PF12931.7 KXL42702.1 - 8.1e-99 331.1 0.0 1.1e-98 330.6 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 KXL42702.1 - 4.7e-27 94.9 0.0 1.7e-26 93.2 0.0 2.1 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Sec16_N PF12935.7 KXL42702.1 - 0.0019 18.4 34.4 0.0019 18.4 34.4 4.5 2 1 1 3 3 3 1 Vesicle coat trafficking protein Sec16 N-terminus PhoLip_ATPase_C PF16212.5 KXL42703.1 - 3.3e-50 171.2 4.0 3.3e-50 171.2 4.0 1.7 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KXL42703.1 - 8.9e-16 57.3 1.1 1.8e-15 56.4 1.1 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KXL42703.1 - 1.9e-14 54.4 3.7 1.2e-08 35.5 1.8 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXL42703.1 - 1.6e-05 24.9 0.0 0.00038 20.5 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KXL42703.1 - 5.4e-05 22.8 3.7 0.0052 16.3 0.1 2.5 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase_3 PF08282.12 KXL42703.1 - 0.017 14.9 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Antibiotic_NAT PF02522.14 KXL42703.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Aminoglycoside 3-N-acetyltransferase HIGH_NTase1_ass PF16581.5 KXL42703.1 - 0.26 11.2 0.0 0.43 10.5 0.0 1.2 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Lipase_2 PF01674.18 KXL42704.1 - 1.5e-06 27.9 0.0 2.3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 2) Abhydrolase_1 PF00561.20 KXL42704.1 - 0.00034 20.3 0.1 0.0061 16.2 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXL42704.1 - 0.0013 19.4 0.1 0.0016 19.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 KXL42704.1 - 0.0026 17.3 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DUF915 PF06028.11 KXL42704.1 - 0.003 16.9 0.0 0.024 14.0 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Palm_thioest PF02089.15 KXL42704.1 - 0.01 15.7 0.0 0.016 15.0 0.0 1.5 1 1 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_2 PF02230.16 KXL42704.1 - 0.014 15.2 0.0 2.4 7.9 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF676 PF05057.14 KXL42704.1 - 0.03 13.8 0.0 0.12 11.8 0.0 1.8 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KXL42704.1 - 0.078 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Rad51 PF08423.11 KXL42705.1 - 1.4e-43 149.0 0.0 5.1e-43 147.2 0.0 1.7 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KXL42705.1 - 2.3e-07 30.6 0.2 8.7e-07 28.7 0.1 1.9 1 1 1 2 2 2 1 AAA domain RecA PF00154.21 KXL42705.1 - 0.00041 19.9 1.9 0.18 11.3 0.1 2.3 2 0 0 2 2 2 2 recA bacterial DNA recombination protein ATPase PF06745.13 KXL42705.1 - 0.00099 18.5 0.2 0.0041 16.5 0.1 2.0 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 KXL42705.1 - 0.016 14.5 2.9 0.14 11.4 1.9 2.6 2 1 0 2 2 2 0 DnaB-like helicase C terminal domain Carn_acyltransf PF00755.20 KXL42706.1 - 9e-210 698.2 0.0 2.1e-209 697.0 0.0 1.5 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase Sld7_C PF18596.1 KXL42707.1 - 1.6e-25 89.0 0.1 2.9e-25 88.2 0.1 1.5 1 0 0 1 1 1 1 Sld7 C-terminal domain DUF1479 PF07350.12 KXL42707.1 - 0.11 11.2 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Arm PF00514.23 KXL42708.1 - 7.1e-10 38.6 7.8 0.027 14.5 0.4 8.2 9 0 0 9 9 9 3 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KXL42708.1 - 0.071 13.4 1.5 35 5.0 0.0 4.5 3 0 0 3 3 3 0 HEAT repeat PTP2 PF17022.5 KXL42708.1 - 0.13 11.9 0.8 0.27 10.8 0.8 1.4 1 0 0 1 1 1 0 Polar tube protein 2 from Microsporidia Cyclin PF08613.11 KXL42709.1 - 8.1e-32 110.8 0.0 1.1e-31 110.4 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KXL42709.1 - 1.6e-05 24.7 0.0 2.2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Asp PF00026.23 KXL42710.1 - 3.2e-77 260.1 2.6 3.8e-77 259.8 2.6 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXL42710.1 - 2.4e-11 44.2 2.2 1.7e-09 38.1 2.2 2.7 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KXL42710.1 - 0.00077 20.1 0.5 0.91 10.2 0.1 3.5 2 1 0 2 2 2 1 Aspartyl protease Lipocalin_4 PF13648.6 KXL42710.1 - 0.06 14.3 2.1 5.1 8.1 0.1 2.6 2 0 0 2 2 2 0 Lipocalin-like domain TAXi_C PF14541.6 KXL42710.1 - 0.12 12.1 0.0 0.85 9.4 0.0 2.1 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal UPF0220 PF05255.11 KXL42711.1 - 9.3e-71 236.7 5.3 1e-70 236.6 5.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF5337 PF17272.2 KXL42711.1 - 0.31 10.9 3.7 0.85 9.5 0.2 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5337) Abhydrolase_1 PF00561.20 KXL42713.1 - 1.2e-08 34.9 0.0 4.8e-08 33.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXL42713.1 - 2.2e-06 27.1 0.0 5.9e-06 25.7 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 VirJ PF06057.11 KXL42713.1 - 0.053 13.4 0.0 0.091 12.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF726 PF05277.12 KXL42713.1 - 0.11 11.4 0.3 4.3 6.2 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF726) Cohesin_load PF10345.9 KXL42714.1 - 5.7e-108 361.9 16.6 7.3e-108 361.6 16.6 1.0 1 0 0 1 1 1 1 Cohesin loading factor Clathrin PF00637.20 KXL42714.1 - 0.24 11.3 2.0 1.9 8.4 0.2 3.0 3 0 0 3 3 3 0 Region in Clathrin and VPS Vps55 PF04133.14 KXL42715.1 - 3.7e-43 146.2 8.7 4.2e-43 146.0 8.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF4231 PF14015.6 KXL42715.1 - 0.0095 16.4 2.9 0.068 13.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4231) DUF4349 PF14257.6 KXL42715.1 - 0.067 12.6 0.0 0.067 12.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) UNC-50 PF05216.13 KXL42715.1 - 7.1 6.1 9.2 0.23 11.0 1.5 1.9 2 0 0 2 2 2 0 UNC-50 family Proteasome PF00227.26 KXL42716.1 - 4.9e-46 156.6 0.0 6e-46 156.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXL42716.1 - 1.1e-12 47.4 0.4 2e-12 46.6 0.4 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RHH_1 PF01402.21 KXL42716.1 - 0.12 12.4 1.4 0.25 11.3 0.2 2.0 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family ATP-synt_ab PF00006.25 KXL42717.1 - 7.1e-62 208.8 0.0 1.1e-61 208.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KXL42717.1 - 4.8e-22 78.2 0.2 1.9e-21 76.3 0.2 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.29 KXL42717.1 - 0.0075 16.7 0.1 0.95 9.9 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T3SS_ATPase_C PF18269.1 KXL42717.1 - 0.0087 15.9 1.1 0.055 13.3 1.1 2.1 1 1 0 1 1 1 1 T3SS EscN ATPase C-terminal domain ATPase PF06745.13 KXL42717.1 - 0.01 15.2 0.2 0.018 14.4 0.2 1.4 1 0 0 1 1 1 0 KaiC RsgA_GTPase PF03193.16 KXL42717.1 - 0.015 15.3 0.8 0.051 13.5 0.1 2.0 2 0 0 2 2 2 0 RsgA GTPase NB-ARC PF00931.22 KXL42717.1 - 0.015 14.5 0.8 0.077 12.2 0.1 2.1 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.12 KXL42717.1 - 0.037 13.9 0.2 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 KXL42717.1 - 0.084 13.2 0.6 0.48 10.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KXL42717.1 - 0.09 13.2 0.2 0.33 11.3 0.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 KXL42717.1 - 0.099 13.0 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Aminotran_3 PF00202.21 KXL42718.1 - 7.6e-116 387.1 0.0 8.7e-116 386.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KXL42718.1 - 0.093 11.9 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II NodZ PF05830.11 KXL42718.1 - 0.24 10.1 0.0 0.39 9.5 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) DUF3402 PF11882.8 KXL42719.1 - 3.6e-139 464.8 0.0 5.4e-139 464.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 KXL42719.1 - 8.3e-81 271.3 0.0 1.3e-80 270.6 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein PrmC_N PF17827.1 KXL42720.1 - 3.7e-05 24.2 3.0 0.00019 21.9 1.6 2.7 2 1 0 2 2 2 1 PrmC N-terminal domain MTS PF05175.14 KXL42720.1 - 4e-05 23.2 0.1 0.16 11.5 0.1 2.2 1 1 1 2 2 2 2 Methyltransferase small domain N6_Mtase PF02384.16 KXL42720.1 - 0.00061 19.2 0.0 0.013 14.8 0.0 2.1 1 1 0 1 1 1 1 N-6 DNA Methylase Methyltransf_10 PF05971.12 KXL42720.1 - 0.0072 15.7 0.2 0.12 11.7 0.0 2.4 2 1 0 3 3 3 1 RNA methyltransferase Methyltransf_31 PF13847.6 KXL42720.1 - 0.013 15.3 0.0 0.033 14.0 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 KXL42720.1 - 0.036 13.9 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KXL42720.1 - 0.076 13.7 0.0 0.22 12.3 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain XPC-binding PF09280.11 KXL42721.1 - 1.2e-24 85.8 14.5 1.9e-24 85.1 14.5 1.3 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.31 KXL42721.1 - 1.7e-23 82.1 3.9 7.5e-13 48.1 0.5 2.5 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 KXL42721.1 - 5.9e-22 77.2 0.2 9.4e-22 76.6 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KXL42721.1 - 1.6e-08 34.2 0.5 3.1e-08 33.3 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 KXL42721.1 - 0.0035 17.1 0.0 0.44 10.4 0.0 2.4 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain Rad60-SLD_2 PF13881.6 KXL42721.1 - 0.012 15.7 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like WIYLD PF10440.9 KXL42721.1 - 0.057 13.2 0.2 0.6 9.9 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain Ubiquitin_2 PF14560.6 KXL42721.1 - 0.057 13.9 0.1 0.12 12.9 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain DUF1421 PF07223.11 KXL42721.1 - 0.086 12.7 0.0 14 5.6 0.0 2.4 2 0 0 2 2 2 0 UBA-like domain (DUF1421) Ubiquitin_5 PF18037.1 KXL42721.1 - 0.11 12.8 0.1 0.22 11.9 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain MCM_N PF14551.6 KXL42721.1 - 0.17 12.5 0.2 0.39 11.3 0.2 1.5 1 0 0 1 1 1 0 MCM N-terminal domain DUF2407 PF10302.9 KXL42721.1 - 0.21 12.2 0.0 0.42 11.2 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain ATF7IP_BD PF16788.5 KXL42721.1 - 0.69 10.0 2.8 1.5 8.9 2.8 1.5 1 0 0 1 1 1 0 ATF-interacting protein binding domain DUF3585 PF12130.8 KXL42722.1 - 0.0021 18.2 0.7 0.0057 16.8 0.7 1.7 1 0 0 1 1 1 1 Bivalent Mical/EHBP Rab binding domain InPase PF18823.1 KXL42723.1 - 0.0029 17.3 0.2 0.005 16.6 0.2 1.3 1 0 0 1 1 1 1 Inorganic Pyrophosphatase SUIM_assoc PF16619.5 KXL42723.1 - 0.0046 17.0 2.3 0.012 15.6 2.3 1.9 1 1 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 DUF2561 PF10812.8 KXL42724.1 - 0.0049 16.9 0.0 0.0062 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2561) DUF4083 PF13314.6 KXL42724.1 - 0.044 13.7 0.3 0.085 12.8 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) UPF0560 PF10577.9 KXL42724.1 - 0.074 11.5 0.0 0.086 11.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF3377 PF11857.8 KXL42724.1 - 0.084 12.8 1.6 0.18 11.8 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Pox_A14 PF05767.12 KXL42724.1 - 0.099 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 MFS_Mycoplasma PF07672.13 KXL42725.1 - 0.1 11.9 0.3 0.14 11.4 0.3 1.3 1 1 0 1 1 1 0 Mycoplasma MFS transporter Phosphodiest PF01663.22 KXL42726.1 - 7.1e-15 55.4 0.5 1.2e-14 54.7 0.5 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KXL42726.1 - 9.4e-07 28.5 0.1 1.6e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 KXL42726.1 - 6.5e-05 22.4 0.5 0.00011 21.7 0.5 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily PglZ PF08665.12 KXL42726.1 - 0.028 14.5 0.1 1.9 8.5 0.1 2.3 2 0 0 2 2 2 0 PglZ domain Aldedh PF00171.22 KXL42728.1 - 2.7e-137 458.1 0.5 3.1e-137 457.9 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KXL42728.1 - 0.02 14.0 0.0 0.039 13.0 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF1344 PF07076.11 KXL42728.1 - 0.12 12.3 0.1 15 5.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) Thioredoxin PF00085.20 KXL42729.1 - 1.4e-25 89.2 0.0 1.6e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KXL42729.1 - 3e-06 27.5 0.0 0.00031 21.0 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KXL42729.1 - 3.4e-06 27.5 0.1 1.1e-05 25.9 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KXL42729.1 - 2.5e-05 23.8 0.0 2.6e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 KXL42729.1 - 0.0044 16.8 0.0 0.0054 16.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KXL42729.1 - 0.0081 16.1 0.1 1.1 9.2 0.0 2.1 1 1 0 2 2 2 1 AhpC/TSA family TraF PF13728.6 KXL42729.1 - 0.0097 15.8 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein HyaE PF07449.11 KXL42729.1 - 0.014 15.4 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_5 PF13743.6 KXL42729.1 - 0.026 14.2 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.6 KXL42729.1 - 0.052 13.7 0.1 0.092 12.9 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like GDPD PF03009.17 KXL42730.1 - 1.8e-55 188.5 0.0 2.8e-55 187.9 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 KXL42730.1 - 1.4e-23 83.3 0.6 9.5e-12 45.3 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXL42730.1 - 4.7e-21 74.9 0.2 5.5e-06 26.8 0.0 5.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXL42730.1 - 5.2e-20 71.2 0.1 5.9e-12 45.6 0.1 4.6 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXL42730.1 - 3.8e-14 51.4 2.0 0.00028 21.1 0.0 6.4 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 KXL42730.1 - 3.2e-10 40.0 5.6 0.0011 19.3 0.0 6.4 7 0 0 7 7 7 2 Ankyrin repeat SPX PF03105.19 KXL42730.1 - 5.8e-05 23.2 0.3 9.4e-05 22.5 0.3 1.3 1 0 0 1 1 1 1 SPX domain PI-PLC-X PF00388.19 KXL42730.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Gpr1_Fun34_YaaH PF01184.19 KXL42731.1 - 4.9e-26 91.6 13.3 6e-26 91.3 13.3 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Sugar_tr PF00083.24 KXL42732.1 - 2.3e-36 125.7 19.3 1.2e-35 123.2 19.3 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL42732.1 - 5.8e-27 94.5 29.2 2.7e-20 72.6 14.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily LIP PF03583.14 KXL42733.1 - 8.8e-62 209.0 0.2 1.3e-61 208.5 0.2 1.1 1 0 0 1 1 1 1 Secretory lipase CRC_subunit PF08624.10 KXL42734.1 - 5.4e-53 179.0 0.2 9.2e-53 178.3 0.2 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Spt5_N PF11942.8 KXL42734.1 - 3.1 8.8 15.6 1.1 10.3 3.8 3.1 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Cyclin PF08613.11 KXL42735.1 - 5.3e-13 49.6 0.0 1e-12 48.7 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KXL42735.1 - 5.7e-05 22.9 0.0 9.7e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Arginosuc_synth PF00764.19 KXL42737.1 - 1e-156 522.1 0.0 1.2e-156 521.9 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KXL42737.1 - 0.012 15.1 0.0 0.031 13.8 0.0 1.6 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KXL42737.1 - 0.04 12.7 0.0 0.057 12.2 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase NTP_transf_9 PF04248.12 KXL42738.1 - 1.5e-34 117.7 0.2 1.8e-34 117.4 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Yip1 PF04893.17 KXL42740.1 - 4.1e-07 29.9 14.0 3.7e-06 26.8 14.0 2.3 1 1 0 1 1 1 1 Yip1 domain HRI1 PF16815.5 KXL42741.1 - 4.6e-72 242.5 3.4 5.1e-72 242.3 3.4 1.0 1 0 0 1 1 1 1 Protein HRI1 Bac_surface_Ag PF01103.23 KXL42744.1 - 7.3e-41 140.7 0.3 9.4e-41 140.3 0.3 1.1 1 0 0 1 1 1 1 Surface antigen ShlB PF03865.13 KXL42744.1 - 0.021 14.3 0.5 0.078 12.4 0.1 1.9 2 0 0 2 2 2 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB Peripla_BP_2 PF01497.18 KXL42744.1 - 0.028 14.0 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein Hist_deacetyl PF00850.19 KXL42746.1 - 1.6e-55 188.8 0.9 5e-55 187.1 0.4 1.9 1 1 1 2 2 2 1 Histone deacetylase domain Peptidase_M76 PF09768.9 KXL42747.1 - 1.7e-66 223.2 0.1 2.1e-66 222.9 0.1 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 KXL42747.1 - 0.0085 15.9 2.6 0.011 15.6 0.5 2.0 1 1 1 2 2 2 1 SprT-like family Peptidase_M91 PF14891.6 KXL42747.1 - 0.064 13.6 0.1 0.096 13.0 0.1 1.2 1 0 0 1 1 1 0 Effector protein DDE_1 PF03184.19 KXL42748.1 - 6.2e-06 26.0 0.0 6.2e-06 26.0 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Cupin_2 PF07883.11 KXL42749.1 - 0.012 15.3 0.4 0.012 15.3 0.4 1.6 2 0 0 2 2 2 0 Cupin domain Membr_traf_MHD PF10540.9 KXL42750.1 - 2.7e-21 76.3 2.3 2.4e-18 66.7 2.3 2.7 1 1 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 KXL42750.1 - 4.1e-16 59.2 0.0 9.2e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.11 KXL42750.1 - 0.0013 17.3 0.1 0.0013 17.3 0.1 1.8 2 0 0 2 2 2 1 Plant family of unknown function (DUF810) HLH PF00010.26 KXL42751.1 - 4.1e-09 36.3 0.0 8.3e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CPSase_L_D3 PF02787.19 KXL42751.1 - 0.14 12.5 2.3 0.2 12.0 0.3 1.9 1 1 1 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CENP-Q PF13094.6 KXL42751.1 - 4.8 7.4 8.8 0.17 12.0 1.9 2.0 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Cwf_Cwc_15 PF04889.12 KXL42751.1 - 5.2 6.7 17.0 15 5.2 17.0 1.7 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein VWA_3 PF13768.6 KXL42752.1 - 1.4e-25 90.1 0.0 2.5e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.10 KXL42752.1 - 1.5e-21 76.7 0.0 4.6e-21 75.1 0.0 1.9 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 KXL42752.1 - 5e-10 39.9 0.1 1.3e-09 38.5 0.1 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KXL42752.1 - 5.2e-08 33.5 0.0 1.3e-07 32.2 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 KXL42752.1 - 5e-07 29.5 0.0 1.2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.14 KXL42752.1 - 0.0043 16.5 0.0 0.0085 15.5 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein F-box PF00646.33 KXL42753.1 - 2.6e-05 24.0 2.3 4.3e-05 23.3 1.2 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KXL42753.1 - 0.00028 20.7 0.3 0.00072 19.4 0.3 1.7 1 0 0 1 1 1 1 F-box-like Nuf2 PF03800.14 KXL42754.1 - 8.5e-42 142.6 0.2 8.5e-42 142.6 0.2 2.5 3 0 0 3 3 3 1 Nuf2 family DHR10 PF18595.1 KXL42754.1 - 3.5e-28 98.0 22.0 3.5e-28 98.0 22.0 3.7 3 0 0 3 3 3 2 Designed helical repeat protein 10 domain Spc7 PF08317.11 KXL42754.1 - 1.5 7.6 56.6 1.7 7.4 12.5 3.4 1 1 2 3 3 3 0 Spc7 kinetochore protein UPF0242 PF06785.11 KXL42754.1 - 3.1 7.8 52.7 0.16 12.0 3.6 3.5 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus AAA_13 PF13166.6 KXL42754.1 - 4.6 5.8 40.2 0.19 10.3 12.4 3.0 1 1 2 3 3 3 0 AAA domain ATP-synt_G PF04718.15 KXL42754.1 - 6.9 7.6 10.3 32 5.4 0.1 3.7 2 1 2 4 4 4 0 Mitochondrial ATP synthase g subunit HrpB7 PF09486.10 KXL42754.1 - 7 7.0 49.6 0.026 14.9 16.8 3.9 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) Adaptin_N PF01602.20 KXL42756.1 - 1.5e-95 320.7 0.7 2.1e-95 320.3 0.7 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KXL42756.1 - 8.9e-16 58.3 0.3 3.4e-12 46.7 0.0 4.4 3 2 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KXL42756.1 - 3.7e-09 36.0 0.5 0.011 15.9 0.0 5.4 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 KXL42756.1 - 4.5e-09 36.6 8.8 0.0012 19.2 0.1 6.0 3 2 4 7 7 7 5 HEAT repeats RTP1_C1 PF10363.9 KXL42756.1 - 0.002 18.3 0.0 4.4 7.5 0.0 3.7 3 1 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 Cohesin_HEAT PF12765.7 KXL42756.1 - 0.0026 18.0 0.2 1.5 9.2 0.0 2.9 2 0 0 2 2 2 2 HEAT repeat associated with sister chromatid cohesion Telomere_reg-2 PF10193.9 KXL42756.1 - 0.074 13.5 0.1 4.6 7.7 0.0 3.0 2 0 0 2 2 2 0 Telomere length regulation protein TMEM119 PF15724.5 KXL42756.1 - 2.5 8.1 6.5 5.4 7.0 6.5 1.5 1 0 0 1 1 1 0 TMEM119 family Metallophos PF00149.28 KXL42758.1 - 2.2e-34 119.8 0.2 2.8e-34 119.4 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KXL42758.1 - 0.043 14.3 0.3 0.1 13.0 0.3 1.7 1 1 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 KXL42758.1 - 0.06 13.5 0.0 0.095 12.9 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Svf1_C PF17187.4 KXL42759.1 - 2.3e-54 183.7 0.0 3.8e-54 182.9 0.0 1.4 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 KXL42759.1 - 1e-53 181.7 0.0 1.4e-53 181.3 0.0 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Acetyltransf_7 PF13508.7 KXL42760.1 - 0.087 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LAT PF15234.6 KXL42760.1 - 0.23 11.2 1.0 0.34 10.6 1.0 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells DUF3439 PF11921.8 KXL42760.1 - 0.61 10.1 13.3 1.1 9.2 13.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) RRM_1 PF00076.22 KXL42762.1 - 5.4e-19 67.8 0.1 2.4e-10 40.1 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXL42762.1 - 0.0011 18.7 0.0 2.1 8.3 0.0 2.4 2 0 0 2 2 2 2 Occluded RNA-recognition motif DUF2406 PF10295.9 KXL42764.1 - 2.2e-23 82.7 0.4 6.9e-23 81.1 0.4 1.9 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) VMA21 PF09446.10 KXL42765.1 - 3.7e-16 59.0 7.6 5.3e-16 58.5 7.6 1.2 1 0 0 1 1 1 1 VMA21-like domain TraQ PF09679.10 KXL42765.1 - 0.1 12.5 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) SNF2_N PF00176.23 KXL42766.1 - 2.9e-53 180.8 0.1 5.7e-53 179.8 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXL42766.1 - 3.3e-16 59.6 0.0 7.6e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL42766.1 - 5.9e-09 36.2 0.0 1.4e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KXL42766.1 - 8.6e-05 22.4 0.0 0.00018 21.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 KXL42766.1 - 0.00012 21.4 0.3 0.00068 18.9 0.1 2.1 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase PhoH PF02562.16 KXL42766.1 - 0.031 13.7 0.0 0.076 12.5 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein RraB PF06877.11 KXL42766.1 - 0.054 14.2 0.0 0.15 12.8 0.0 1.8 1 0 0 1 1 1 0 Regulator of ribonuclease activity B DEAD_2 PF06733.15 KXL42766.1 - 0.085 12.5 0.0 0.51 9.9 0.0 2.1 2 0 0 2 2 2 0 DEAD_2 HIGH_NTase1_ass PF16581.5 KXL42766.1 - 0.11 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region UcrQ PF02939.16 KXL42767.1 - 2.7e-24 84.9 0.1 2.8e-24 84.9 0.1 1.0 1 0 0 1 1 1 1 UcrQ family Calreticulin PF00262.18 KXL42768.1 - 2.3e-174 579.5 15.8 3.2e-174 579.0 15.8 1.2 1 0 0 1 1 1 1 Calreticulin family G0-G1_switch_2 PF15103.6 KXL42768.1 - 0.24 11.8 0.2 0.24 11.8 0.2 2.1 2 0 0 2 2 2 0 G0/G1 switch protein 2 OAD_gamma PF04277.13 KXL42768.1 - 1.3 9.7 5.4 1.8 9.2 0.4 3.0 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Fungal_trans_2 PF11951.8 KXL42769.1 - 1e-12 47.6 0.3 1.3e-12 47.2 0.3 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL42770.1 - 1.2e-07 31.7 9.9 1.2e-07 31.7 9.9 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 KXL42771.1 - 3.4e-47 161.1 0.0 4.2e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ADH_N PF08240.12 KXL42772.1 - 2.3e-27 95.0 3.4 3.6e-27 94.4 3.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXL42772.1 - 6.3e-14 52.1 0.0 9.8e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXL42772.1 - 5.8e-09 35.7 1.4 4e-08 33.0 1.4 2.2 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Flexi_CP_N PF08358.10 KXL42772.1 - 0.2 11.7 0.0 0.46 10.5 0.0 1.6 1 0 0 1 1 1 0 Carlavirus coat Sugar_tr PF00083.24 KXL42773.1 - 8e-78 262.3 26.2 9.7e-78 262.0 26.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL42773.1 - 5e-17 61.8 32.2 4.8e-16 58.6 32.3 2.3 2 1 1 3 3 3 1 Major Facilitator Superfamily DUF1593 PF07632.11 KXL42774.1 - 3.6e-91 305.2 0.0 4.7e-91 304.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.15 KXL42774.1 - 0.0027 16.6 0.0 0.0041 16.0 0.0 1.2 1 0 0 1 1 1 1 REJ domain Epimerase PF01370.21 KXL42775.1 - 1.9e-08 34.1 0.1 0.00016 21.3 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXL42775.1 - 1.3e-06 28.4 0.2 2.9e-06 27.3 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KXL42775.1 - 4.8e-05 23.8 0.0 9.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 KXL42775.1 - 0.0094 15.5 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 KXL42775.1 - 0.14 11.3 0.2 0.49 9.4 0.0 1.9 2 1 1 3 3 3 0 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 KXL42775.1 - 0.15 12.4 0.0 0.38 11.0 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Sugar_tr PF00083.24 KXL42776.1 - 4.6e-80 269.7 28.6 5.7e-80 269.4 28.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL42776.1 - 1.3e-25 90.0 60.6 3.3e-21 75.6 35.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_127 PF07944.12 KXL42777.1 - 4e-59 200.5 0.0 3.4e-44 151.2 0.0 2.3 1 1 1 2 2 2 2 Beta-L-arabinofuranosidase, GH127 ADH_zinc_N PF00107.26 KXL42778.1 - 8.4e-22 77.5 0.0 1.2e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KXL42778.1 - 2.9e-18 65.7 0.0 5e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KXL42778.1 - 3e-06 28.3 0.0 5e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans PF04082.18 KXL42779.1 - 1.8e-23 82.9 0.1 2.8e-23 82.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL42779.1 - 5.3e-08 32.9 13.2 9.6e-08 32.0 13.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MscS_porin PF12795.7 KXL42779.1 - 0.081 12.5 0.5 0.15 11.6 0.5 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain TolA_bind_tri PF16331.5 KXL42779.1 - 2.5 8.2 5.5 0.87 9.7 2.3 1.8 2 0 0 2 2 2 0 TolA binding protein trimerisation MR_MLE_C PF13378.6 KXL42780.1 - 1.6e-42 145.5 0.0 2.3e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KXL42780.1 - 6.7e-09 36.0 0.0 1.1e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain PEP_mutase PF13714.6 KXL42782.1 - 3.7e-45 154.2 0.1 4.3e-45 154.0 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KXL42782.1 - 4.9e-21 74.8 0.2 7.1e-21 74.3 0.2 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Succ_CoA_lig PF13607.6 KXL42782.1 - 0.071 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain SCP2 PF02036.17 KXL42783.1 - 2.7e-25 88.8 0.6 3.1e-25 88.6 0.6 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KXL42783.1 - 6e-07 29.8 0.1 7e-07 29.6 0.1 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal DUF402 PF04167.13 KXL42783.1 - 0.097 12.9 0.0 0.22 11.7 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF402) NUP50 PF08911.11 KXL42784.1 - 7.3e-06 26.6 0.5 7.3e-06 26.6 0.5 7.7 7 1 0 7 7 7 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.18 KXL42784.1 - 1.7e-05 25.0 0.0 4.1e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 RanBP1 domain GWT1 PF06423.12 KXL42785.1 - 8.5e-40 136.3 0.0 3e-39 134.5 0.0 2.0 1 0 0 1 1 1 1 GWT1 DDE_Tnp_IS1595 PF12762.7 KXL42786.1 - 0.18 11.8 0.0 0.45 10.5 0.0 1.6 1 0 0 1 1 1 0 ISXO2-like transposase domain ADH_N PF08240.12 KXL42788.1 - 3.6e-27 94.4 2.7 8.4e-27 93.2 2.7 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXL42788.1 - 3.2e-08 33.6 0.1 9e-05 22.5 0.0 2.7 2 1 0 3 3 3 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KXL42788.1 - 3.7e-06 26.7 0.3 3.7e-06 26.7 0.3 2.6 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-associated Abhydrolase_3 PF07859.13 KXL42789.1 - 3.4e-54 183.9 0.0 6.3e-54 183.0 0.0 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 KXL42789.1 - 0.0002 20.4 0.0 0.00079 18.4 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KXL42789.1 - 0.17 11.3 0.0 0.51 9.8 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family fn3 PF00041.21 KXL42790.1 - 4.6e-05 23.7 0.0 0.00015 22.1 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III domain LNS2 PF08235.13 KXL42791.1 - 2e-89 298.9 0.0 3e-89 298.4 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KXL42791.1 - 6.2e-42 141.7 0.0 1.3e-41 140.7 0.0 1.6 1 0 0 1 1 1 1 lipin, N-terminal conserved region Nop14 PF04147.12 KXL42791.1 - 8.1 4.5 31.7 12 4.0 31.7 1.1 1 0 0 1 1 1 0 Nop14-like family Rhodanese PF00581.20 KXL42792.1 - 2e-10 41.1 0.0 2.8e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain FYVE PF01363.21 KXL42793.1 - 2.5e-06 27.5 2.2 5.1e-06 26.5 2.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 KXL42793.1 - 0.17 12.1 3.6 0.35 11.1 3.6 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger DUF4047 PF13256.6 KXL42794.1 - 0.031 14.5 0.0 0.033 14.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) MCR PF18509.1 KXL42795.1 - 0.052 13.1 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 Magnetochrome domain Goodbye PF17109.5 KXL42796.1 - 4.1e-34 117.6 1.6 5.3e-31 107.6 0.0 2.7 2 1 0 2 2 2 2 fungal STAND N-terminal Goodbye domain 2-Hacid_dh_C PF02826.19 KXL42796.1 - 0.0068 15.8 0.2 0.026 13.9 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TRIF-NTD PF17798.1 KXL42796.1 - 0.0096 16.0 1.4 0.011 15.8 0.2 1.7 2 0 0 2 2 2 1 TRIF N-terminal domain TAFH PF07531.14 KXL42796.1 - 0.035 14.2 0.7 0.12 12.5 0.6 1.9 1 1 0 1 1 1 0 NHR1 homology to TAF DUF2730 PF10805.8 KXL42796.1 - 0.91 9.7 7.9 0.48 10.5 3.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) Occludin_ELL PF07303.13 KXL42796.1 - 3.3 8.5 6.0 12 6.7 1.2 2.8 3 1 0 3 3 3 0 Occludin homology domain DSPc PF00782.20 KXL42797.1 - 2.6e-10 40.2 0.1 4.1e-10 39.6 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KXL42797.1 - 0.03 14.6 0.0 0.044 14.1 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain Sec5 PF15469.6 KXL42798.1 - 6.7e-40 136.9 0.8 2.2e-39 135.2 0.0 2.3 3 0 0 3 3 3 1 Exocyst complex component Sec5 Vps51 PF08700.11 KXL42798.1 - 8.4e-06 25.8 0.0 4e-05 23.6 0.0 2.2 1 0 0 1 1 1 1 Vps51/Vps67 Sec15 PF04091.12 KXL42798.1 - 0.02 14.3 0.1 0.042 13.2 0.1 1.6 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like Iso_dh PF00180.20 KXL42799.1 - 4.1e-100 335.3 0.0 4.9e-100 335.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HHH_2 PF12826.7 KXL42799.1 - 0.047 13.8 0.0 0.41 10.8 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif Sugar_tr PF00083.24 KXL42800.1 - 1.7e-87 294.2 25.3 2e-87 294.0 25.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL42800.1 - 2e-38 132.2 50.1 7.8e-32 110.6 25.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HP0268 PF18618.1 KXL42800.1 - 0.038 14.4 0.0 0.07 13.6 0.0 1.4 1 0 0 1 1 1 0 HP0268 ADH_N_2 PF16884.5 KXL42801.1 - 0.042 13.8 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Glyco_hydro_3_C PF01915.22 KXL42802.1 - 4.8e-47 160.5 0.0 8.5e-47 159.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXL42802.1 - 6.6e-36 124.3 0.0 1.3e-35 123.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXL42802.1 - 5.2e-18 64.9 0.0 9.2e-18 64.1 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Aminotran_1_2 PF00155.21 KXL42803.1 - 5.3e-43 147.6 0.0 7.2e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KXL42803.1 - 6.8e-05 21.6 0.0 0.00012 20.8 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KXL42803.1 - 0.032 13.2 0.0 0.054 12.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Beta_elim_lyase PF01212.21 KXL42803.1 - 0.059 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Alliinase_C PF04864.13 KXL42803.1 - 0.18 10.7 0.0 0.28 10.0 0.0 1.3 1 0 0 1 1 1 0 Allinase Acetyltransf_10 PF13673.7 KXL42805.1 - 4e-05 23.6 0.0 0.00028 20.8 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXL42805.1 - 0.00079 19.7 0.0 0.0013 18.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXL42805.1 - 0.013 15.9 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXL42805.1 - 0.037 14.2 0.0 0.083 13.0 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF745 PF05335.13 KXL42806.1 - 0.0041 16.9 8.8 0.0041 16.9 8.8 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF745) DUF948 PF06103.11 KXL42806.1 - 0.11 12.7 7.6 15 5.9 0.0 4.7 4 1 2 6 6 6 0 Bacterial protein of unknown function (DUF948) FAM76 PF16046.5 KXL42806.1 - 2.1 7.6 23.8 2.1 7.6 6.8 2.5 1 1 1 2 2 2 0 FAM76 protein BCDHK_Adom3 PF10436.9 KXL42806.1 - 2.9 7.7 5.4 15 5.4 0.2 2.7 1 1 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DUF2120 PF09893.9 KXL42806.1 - 3.9 7.6 7.6 14 5.8 0.4 2.9 1 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) Fib_alpha PF08702.10 KXL42806.1 - 7.4 6.8 25.7 2.2 8.5 3.4 4.4 3 1 0 4 4 4 0 Fibrinogen alpha/beta chain family MFS_1 PF07690.16 KXL42808.1 - 1.4e-39 136.0 22.0 1.4e-39 136.0 22.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL42808.1 - 1.4e-13 50.5 5.3 1.4e-13 50.5 5.3 2.4 2 1 1 3 3 3 1 Sugar (and other) transporter RTA1 PF04479.13 KXL42809.1 - 9.2e-47 159.3 19.0 9.2e-47 159.3 19.0 1.6 1 1 0 1 1 1 1 RTA1 like protein ABC2_membrane PF01061.24 KXL42810.1 - 6.2e-39 133.6 22.9 6.2e-39 133.6 22.9 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KXL42810.1 - 1.3e-24 87.2 0.8 2e-24 86.6 0.0 1.7 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.7 KXL42810.1 - 1.9e-06 27.3 25.1 1.9e-06 27.3 25.1 2.8 2 1 1 3 3 3 1 ABC-2 family transporter protein AAA_21 PF13304.6 KXL42810.1 - 0.0026 17.6 0.0 1.2 8.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Syndecan PF01034.20 KXL42810.1 - 0.05 13.5 0.1 0.31 11.0 0.0 2.4 2 0 0 2 2 2 0 Syndecan domain AAA_16 PF13191.6 KXL42810.1 - 0.15 12.4 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KXL42810.1 - 0.18 11.6 0.3 0.45 10.3 0.3 1.7 1 1 0 1 1 1 0 P-loop containing region of AAA domain ABC2_membrane_2 PF12679.7 KXL42810.1 - 0.45 9.7 19.9 0.45 9.7 16.5 2.5 2 1 0 2 2 2 0 ABC-2 family transporter protein EGF PF00008.27 KXL42810.1 - 7.7 6.9 19.3 1.8 8.9 0.2 3.6 3 0 0 3 3 3 0 EGF-like domain DUF397 PF04149.12 KXL42811.1 - 0.18 11.9 1.9 0.39 10.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF397) SPX PF03105.19 KXL42811.1 - 0.85 9.5 11.1 1.1 9.2 11.1 1.1 1 0 0 1 1 1 0 SPX domain QWRF PF04484.12 KXL42811.1 - 5 6.8 10.7 6.8 6.3 10.7 1.2 1 0 0 1 1 1 0 QWRF family Joubert PF15392.6 KXL42811.1 - 7.5 6.2 10.1 9.7 5.8 10.1 1.1 1 0 0 1 1 1 0 Joubert syndrome-associated ADH_zinc_N PF00107.26 KXL42813.1 - 1.4e-15 57.4 0.0 2.3e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXL42813.1 - 0.0081 16.0 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KXL42813.1 - 0.029 14.3 0.1 0.44 10.5 0.1 2.4 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase AAR2 PF05282.11 KXL42813.1 - 0.09 12.2 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 AAR2 protein RNase_T PF00929.24 KXL42814.1 - 2.3e-27 96.6 0.3 2.6e-27 96.4 0.3 1.0 1 0 0 1 1 1 1 Exonuclease bZIP_1 PF00170.21 KXL42815.1 - 3.6e-09 36.6 8.6 1.1e-08 35.0 8.6 1.8 1 1 0 1 1 1 1 bZIP transcription factor ATG16 PF08614.11 KXL42815.1 - 0.054 13.7 6.0 0.11 12.7 6.0 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF501 PF04417.12 KXL42815.1 - 0.066 13.0 0.8 0.25 11.2 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF501) Mod_r PF07200.13 KXL42815.1 - 0.084 13.0 3.2 3.5 7.7 2.6 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein dsrm PF00035.26 KXL42815.1 - 0.13 13.0 0.8 0.28 11.9 0.1 2.0 2 0 0 2 2 2 0 Double-stranded RNA binding motif bZIP_2 PF07716.15 KXL42815.1 - 0.19 11.8 12.2 9.3 6.4 12.2 2.3 1 1 0 1 1 1 0 Basic region leucine zipper VIR_N PF15912.5 KXL42815.1 - 5 6.6 8.2 1.5 8.4 5.5 1.4 2 0 0 2 2 2 0 Virilizer, N-terminal OmpH PF03938.14 KXL42815.1 - 5.8 7.3 10.5 0.44 10.9 6.0 1.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF3445 PF11927.8 KXL42816.1 - 2.6e-77 259.4 0.0 3.1e-77 259.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF3294 PF07957.11 KXL42817.1 - 0.019 14.8 0.0 0.02 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) BTB PF00651.31 KXL42819.1 - 0.0047 17.2 0.0 0.0095 16.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Glyco_transf_8C PF08437.10 KXL42819.1 - 0.14 12.2 0.1 0.3 11.2 0.1 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 8 C-terminal MFS_1 PF07690.16 KXL42820.1 - 2.3e-20 72.8 50.1 3.5e-19 68.9 40.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Flavi_NS4A PF01350.17 KXL42820.1 - 2.4 8.1 7.5 0.19 11.7 1.9 2.0 3 0 0 3 3 3 0 Flavivirus non-structural protein NS4A Anoctamin PF04547.12 KXL42821.1 - 2.9e-116 389.0 0.4 4.2e-116 388.5 0.4 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel Sugar_tr PF00083.24 KXL42822.1 - 2.9e-88 296.7 19.9 3.3e-88 296.5 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL42822.1 - 3.8e-16 59.0 22.9 3.8e-16 59.0 22.9 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 KXL42822.1 - 1.1e-05 24.3 14.8 0.0056 15.3 2.8 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein Methyltransf_23 PF13489.6 KXL42823.1 - 5.1e-26 91.5 0.0 7.3e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL42823.1 - 5.1e-11 43.1 0.0 1.2e-10 42.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL42823.1 - 5.8e-09 36.5 0.0 1e-08 35.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL42823.1 - 6.5e-09 35.8 0.0 0.00058 19.7 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KXL42823.1 - 8.3e-09 36.1 0.0 3.2e-08 34.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXL42823.1 - 0.0062 16.1 0.0 0.013 15.0 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.19 KXL42823.1 - 0.012 15.7 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KXL42823.1 - 0.017 14.6 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.13 KXL42823.1 - 0.02 14.3 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 KXL42823.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain ZapB PF06005.12 KXL42824.1 - 0.0024 18.2 0.3 0.52 10.8 0.2 2.9 2 1 0 2 2 2 2 Cell division protein ZapB Sugar_tr PF00083.24 KXL42825.1 - 2.7e-71 240.8 22.1 3.1e-71 240.6 22.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL42825.1 - 2e-19 69.8 41.5 6.7e-14 51.6 17.8 2.5 1 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXL42825.1 - 3.9e-08 32.3 25.9 1.4e-06 27.2 2.0 3.1 3 1 1 4 4 4 2 MFS/sugar transport protein BT1 PF03092.16 KXL42825.1 - 0.0002 19.7 5.7 0.0032 15.8 0.6 3.1 3 0 0 3 3 3 2 BT1 family MFS_3 PF05977.13 KXL42825.1 - 1.2 7.5 11.4 0.064 11.6 2.1 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector COesterase PF00135.28 KXL42826.1 - 5.8e-55 187.1 0.0 7.8e-55 186.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXL42826.1 - 4.2e-06 26.8 0.0 0.0022 17.9 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Esterase PF00756.20 KXL42826.1 - 0.061 13.0 0.0 0.31 10.6 0.0 2.0 2 0 0 2 2 2 0 Putative esterase GFO_IDH_MocA_C PF02894.17 KXL42827.1 - 1e-19 70.6 0.1 2.5e-19 69.4 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.22 KXL42827.1 - 5.3e-18 66.0 0.0 8.9e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KXL42827.1 - 0.029 15.0 0.0 0.044 14.4 0.0 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain B12-binding PF02310.19 KXL42827.1 - 0.097 12.7 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 B12 binding domain Peripla_BP_2 PF01497.18 KXL42827.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein Prenyltransf PF01255.19 KXL42828.1 - 7.5e-81 270.9 0.8 1.7e-80 269.8 0.8 1.5 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase zn-ribbon_14 PF16503.5 KXL42829.1 - 5.6e-18 64.1 3.0 5.6e-18 64.1 3.0 3.1 3 0 0 3 3 3 1 Zinc-ribbon ATP_bind_3 PF01171.20 KXL42829.1 - 1.3e-16 60.9 0.0 2.2e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 PP-loop family RecR PF02132.15 KXL42829.1 - 0.00033 20.2 0.6 0.00033 20.2 0.6 2.8 4 0 0 4 4 4 1 RecR protein tRNA_Me_trans PF03054.16 KXL42829.1 - 0.039 12.8 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase DPBB_1 PF03330.18 KXL42830.1 - 0.035 14.4 2.6 0.15 12.4 2.6 2.0 1 1 0 1 1 1 0 Lytic transglycolase OCD_Mu_crystall PF02423.15 KXL42831.1 - 5.1e-11 42.1 0.0 0.00012 21.1 0.0 3.7 4 0 0 4 4 4 3 Ornithine cyclodeaminase/mu-crystallin family FAD_binding_3 PF01494.19 KXL42832.1 - 1e-14 54.6 0.4 1.8e-11 43.9 0.2 3.1 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXL42832.1 - 0.0036 17.5 1.3 0.0046 17.2 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KXL42832.1 - 0.078 12.3 0.1 7.8 5.7 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Arylsulfotran_2 PF14269.6 KXL42833.1 - 3.1e-61 207.4 1.2 5e-61 206.7 1.2 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXL42833.1 - 9.3e-20 70.9 0.2 4.5e-19 68.6 0.1 1.8 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) ADH_zinc_N PF00107.26 KXL42834.1 - 1.6e-08 34.6 0.0 2.9e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXL42834.1 - 2.3e-06 27.4 0.2 7.5e-06 25.8 0.1 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXL42834.1 - 0.01 16.9 0.0 0.034 15.2 0.0 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Zn_clus PF00172.18 KXL42835.1 - 1e-06 28.7 10.6 1.7e-06 28.0 10.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.10 KXL42835.1 - 0.92 9.9 5.3 1.7 9.0 5.3 1.5 1 0 0 1 1 1 0 Opy2 protein Methyltransf_23 PF13489.6 KXL42836.1 - 3.7e-14 52.9 0.0 4.5e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL42836.1 - 1.2e-06 29.1 0.0 4.3e-06 27.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL42836.1 - 6e-05 22.9 0.0 0.0011 18.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL42836.1 - 8.7e-05 23.2 0.0 0.0029 18.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL42836.1 - 0.00045 20.8 0.0 0.0018 18.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXL42836.1 - 0.022 14.0 0.0 0.2 10.9 0.0 2.0 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 KXL42836.1 - 0.023 14.8 0.0 0.035 14.2 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KXL42836.1 - 0.025 13.9 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain MTS PF05175.14 KXL42836.1 - 0.026 14.1 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain HpcH_HpaI PF03328.14 KXL42837.1 - 6.8e-31 107.1 0.0 8.5e-31 106.8 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family GHMP_kinases_C PF08544.13 KXL42837.1 - 0.13 12.6 0.1 1.3 9.4 0.0 2.4 2 0 0 2 2 2 0 GHMP kinases C terminal RsbRD_N PF14361.6 KXL42837.1 - 0.14 12.9 0.0 0.34 11.6 0.0 1.6 1 0 0 1 1 1 0 RsbT co-antagonist protein rsbRD N-terminal domain DUF836 PF05768.14 KXL42838.1 - 5.8e-13 49.1 0.0 7.3e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 KXL42838.1 - 0.043 14.0 0.0 0.06 13.6 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin CHORD PF04968.12 KXL42839.1 - 2.6e-48 162.6 23.0 4.6e-24 84.9 9.9 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.16 KXL42839.1 - 2.6e-10 41.2 1.0 3.2e-10 40.9 0.3 1.5 2 0 0 2 2 2 1 CS domain BTK PF00779.19 KXL42839.1 - 2.6 7.9 11.8 2.7 7.9 0.5 3.3 3 0 0 3 3 3 0 BTK motif WD40 PF00400.32 KXL42840.1 - 4.2e-19 68.5 11.8 0.00026 21.7 0.3 6.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL42840.1 - 2.9e-14 53.1 0.0 0.037 14.3 0.0 5.8 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain VID27 PF08553.10 KXL42840.1 - 0.0069 15.5 0.1 0.44 9.6 0.0 2.7 3 0 0 3 3 3 1 VID27 C-terminal WD40-like domain ADH_N PF08240.12 KXL42841.1 - 2.4e-24 85.3 0.5 5.7e-24 84.1 0.5 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXL42841.1 - 5e-17 62.1 1.6 9.7e-17 61.2 1.6 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXL42841.1 - 0.0058 16.0 0.9 0.013 14.9 0.9 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Fringe PF02434.16 KXL42843.1 - 3e-06 26.9 0.9 3.6e-05 23.3 0.9 2.2 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.6 KXL42843.1 - 0.0069 16.3 0.6 0.018 14.9 0.6 1.7 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 KXL42843.1 - 0.017 15.2 0.3 0.037 14.2 0.3 1.5 1 0 0 1 1 1 0 PAN-like domain Got1 PF04178.12 KXL42845.1 - 1.7e-34 118.7 12.4 2.1e-34 118.3 12.4 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2070 PF09843.9 KXL42845.1 - 1.5 7.1 7.0 1.8 6.8 7.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) HLH PF00010.26 KXL42847.1 - 3.1e-12 46.3 0.0 1.6e-11 43.9 0.0 2.2 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain HTH_psq PF05225.16 KXL42848.1 - 1.6e-07 30.9 0.1 2e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.6 KXL42848.1 - 0.0027 17.8 0.1 0.0036 17.4 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_8 PF02954.19 KXL42848.1 - 0.055 13.3 0.0 0.092 12.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family SelP_N PF04592.14 KXL42849.1 - 0.36 10.2 7.4 0.61 9.4 7.4 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Ank_5 PF13857.6 KXL42850.1 - 2e-08 34.4 0.0 2.1e-06 27.9 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXL42850.1 - 9.3e-07 29.3 0.0 0.00011 22.7 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXL42850.1 - 7.7e-06 26.4 0.0 1.4e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXL42850.1 - 0.0016 18.8 0.2 0.074 13.6 0.1 2.8 2 1 0 2 2 2 1 Ankyrin repeat Glyco_transf_4 PF13439.6 KXL42850.1 - 0.12 12.4 0.4 3.2 7.7 0.1 2.7 2 1 0 2 2 2 0 Glycosyltransferase Family 4 DUF3788 PF12663.7 KXL42851.1 - 0.11 12.5 0.0 0.11 12.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3788) GFO_IDH_MocA PF01408.22 KXL42852.1 - 1.9e-10 41.6 0.0 3.1e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXL42852.1 - 1.4e-05 25.1 0.0 3.2e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Cro PF09048.10 KXL42852.1 - 0.19 11.8 0.4 1.2 9.2 0.1 2.5 3 0 0 3 3 3 0 Cro DHquinase_II PF01220.19 KXL42853.1 - 3.1e-59 198.6 0.0 3.5e-59 198.4 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II AurF PF11583.8 KXL42853.1 - 0.019 14.3 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 P-aminobenzoate N-oxygenase AurF Peptidase_S41 PF03572.18 KXL42853.1 - 0.11 12.1 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S41 HGD-D PF06050.13 KXL42853.1 - 0.19 11.4 0.0 0.2 11.4 0.0 1.1 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component Sugar_tr PF00083.24 KXL42854.1 - 2e-91 307.2 36.6 2.7e-90 303.4 36.6 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL42854.1 - 9.3e-12 44.5 63.8 2.5e-05 23.4 31.8 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_23 PF13489.6 KXL42855.1 - 1.6e-21 76.9 0.0 2.4e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL42855.1 - 1.1e-11 44.7 0.0 1.4e-10 41.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL42855.1 - 5.9e-11 42.9 0.0 1.3e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL42855.1 - 4.1e-07 30.7 0.0 2.3e-06 28.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL42855.1 - 5.8e-07 30.1 0.0 1.3e-06 28.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KXL42855.1 - 0.00023 21.3 0.0 0.0005 20.2 0.0 1.7 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 KXL42855.1 - 0.00058 19.5 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KXL42855.1 - 0.00081 18.9 0.0 0.0018 17.8 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.20 KXL42855.1 - 0.0017 17.7 0.0 0.004 16.5 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 KXL42855.1 - 0.0025 17.1 0.0 0.0043 16.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Ubie_methyltran PF01209.18 KXL42855.1 - 0.13 11.6 0.0 1.4 8.2 0.0 2.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF2569 PF10754.9 KXL42856.1 - 8 6.9 12.0 0.86 10.0 2.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) AA_permease_2 PF13520.6 KXL42857.1 - 3.6e-45 154.6 52.2 4.8e-45 154.2 52.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXL42857.1 - 3.3e-23 82.0 45.1 4.4e-23 81.6 45.1 1.1 1 0 0 1 1 1 1 Amino acid permease FA_desaturase PF00487.24 KXL42858.1 - 7.1e-14 52.3 25.9 1.2e-13 51.5 25.9 1.4 1 0 0 1 1 1 1 Fatty acid desaturase DUF1993 PF09351.10 KXL42859.1 - 6.9e-22 78.3 0.0 7.6e-22 78.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) USP7_ICP0_bdg PF12436.8 KXL42859.1 - 0.061 12.6 0.0 0.072 12.4 0.0 1.1 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 AAA_12 PF13087.6 KXL42860.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KXL42862.1 - 2.3e-60 204.6 0.0 9.6e-60 202.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KXL42862.1 - 6.1e-38 130.5 0.0 9.3e-38 129.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXL42862.1 - 2.2e-11 43.8 0.0 8.7e-10 38.6 0.0 2.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXL42862.1 - 5.3e-07 30.1 0.0 3.4e-06 27.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KXL42862.1 - 1.8e-05 24.1 0.0 0.0002 20.8 0.0 2.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 KXL42862.1 - 7.5e-05 23.2 0.2 0.00019 21.9 0.2 1.7 1 0 0 1 1 1 1 AAA ATPase domain ResIII PF04851.15 KXL42862.1 - 0.00012 22.1 0.0 0.0038 17.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KXL42862.1 - 0.00032 20.3 0.0 0.0009 18.8 0.0 1.8 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 KXL42862.1 - 0.00045 20.5 0.1 0.0021 18.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 KXL42862.1 - 0.00046 19.3 0.2 0.0019 17.3 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein Viral_helicase1 PF01443.18 KXL42862.1 - 0.0036 17.1 0.1 2.8 7.6 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 KXL42862.1 - 0.0048 16.4 0.0 0.14 11.6 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 KXL42862.1 - 0.0094 15.4 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KXL42862.1 - 0.016 15.2 0.1 0.08 12.9 0.0 2.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KXL42862.1 - 0.019 14.5 0.7 0.17 11.4 0.0 2.8 3 1 1 4 4 4 0 AAA domain PCB_OB PF17092.5 KXL42862.1 - 0.028 15.2 0.9 0.32 11.8 0.1 2.6 2 0 0 2 2 2 0 Penicillin-binding protein OB-like domain FtsK_SpoIIIE PF01580.18 KXL42862.1 - 0.04 13.3 0.0 0.11 11.8 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family Nsp3_PL2pro PF12124.8 KXL42862.1 - 0.045 13.5 0.2 6.7 6.6 0.1 2.5 2 0 0 2 2 2 0 Coronavirus polyprotein cleavage domain AAA PF00004.29 KXL42862.1 - 0.047 14.1 0.2 0.2 12.1 0.0 2.2 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KXL42862.1 - 0.052 13.3 0.0 0.21 11.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 KXL42862.1 - 0.071 13.0 0.0 1.7 8.4 0.0 2.4 2 0 0 2 2 2 0 Helicase ABC_tran PF00005.27 KXL42862.1 - 0.11 13.0 0.0 0.41 11.2 0.0 2.0 2 0 0 2 2 2 0 ABC transporter PIF1 PF05970.14 KXL42862.1 - 0.17 11.0 0.0 15 4.6 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase Abhydrolase_3 PF07859.13 KXL42865.1 - 3.2e-27 95.8 0.0 4.6e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXL42865.1 - 2.9e-18 65.9 0.0 4.7e-18 65.2 0.0 1.3 1 1 0 1 1 1 1 Steryl acetyl hydrolase DUF2974 PF11187.8 KXL42865.1 - 0.079 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Zn_clus PF00172.18 KXL42867.1 - 2.7e-11 43.4 7.0 4.1e-11 42.8 7.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXL42867.1 - 0.0017 17.3 0.0 0.0029 16.5 0.0 1.4 1 1 1 2 2 2 1 Fungal specific transcription factor domain Me-amine-dh_L PF02975.14 KXL42868.1 - 0.0029 18.1 2.2 0.004 17.7 2.2 1.2 1 0 0 1 1 1 1 Methylamine dehydrogenase, L chain KTI12 PF08433.10 KXL42869.1 - 1.5e-82 277.1 0.0 1.7e-82 277.0 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 CPT PF07931.12 KXL42869.1 - 0.00031 20.6 0.0 0.00044 20.1 0.0 1.2 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 KXL42869.1 - 0.0032 17.6 0.0 0.011 16.0 0.0 1.9 2 1 0 2 2 2 1 AAA domain SPX PF03105.19 KXL42870.1 - 6.4 6.6 6.5 6.9 6.5 6.5 1.1 1 0 0 1 1 1 0 SPX domain Methyltransf_34 PF11312.8 KXL42871.1 - 2.8e-98 328.9 0.0 3.5e-98 328.6 0.0 1.0 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Methyltransf_23 PF13489.6 KXL42871.1 - 0.2 11.5 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain SLAC1 PF03595.17 KXL42872.1 - 2.5e-93 312.9 57.6 2.8e-93 312.7 57.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF5056 PF16479.5 KXL42872.1 - 0.028 14.6 2.2 0.061 13.6 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5056) SBDS PF01172.18 KXL42874.1 - 3.9e-22 78.1 0.0 4.4e-22 78.0 0.0 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein UQ_con PF00179.26 KXL42876.1 - 2.4e-45 153.6 0.0 2.9e-45 153.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KXL42876.1 - 0.00064 20.0 0.0 0.00078 19.7 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KXL42876.1 - 0.0034 17.1 0.0 0.0063 16.2 0.0 1.5 1 1 0 1 1 1 1 Prokaryotic E2 family B Cu-oxidase_3 PF07732.15 KXL42877.1 - 8.1e-46 154.9 3.0 1.2e-42 144.6 0.1 3.5 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXL42877.1 - 2.5e-43 147.1 1.9 6.4e-35 119.9 0.1 2.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KXL42877.1 - 9.6e-37 126.5 0.0 1.4e-31 109.8 0.3 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 KXL42877.1 - 0.00089 19.3 0.0 8.7 6.5 0.0 3.8 4 0 0 4 4 4 2 Cupredoxin-like domain DUF2316 PF10078.9 KXL42877.1 - 0.086 13.1 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) Spc24 PF08286.11 KXL42879.1 - 3.5e-31 107.6 0.1 6.8e-30 103.4 0.0 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 APG6_N PF17675.1 KXL42879.1 - 0.05 14.1 5.6 0.068 13.7 5.6 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region SlyX PF04102.12 KXL42879.1 - 0.11 13.1 0.5 18 6.0 0.1 2.4 2 0 0 2 2 2 0 SlyX DUF4164 PF13747.6 KXL42879.1 - 1.6 9.0 8.9 2.3e+02 2.1 8.9 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Fis1_TPR_C PF14853.6 KXL42880.1 - 1.4e-25 89.1 2.2 2.3e-25 88.4 2.2 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 KXL42880.1 - 1.2e-17 63.2 0.1 2.4e-17 62.3 0.1 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 KXL42880.1 - 0.0017 18.3 2.0 0.0038 17.2 2.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXL42880.1 - 0.043 14.3 0.7 0.13 12.7 0.3 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXL42880.1 - 0.18 12.5 1.4 0.35 11.6 0.4 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat PfkB PF00294.24 KXL42882.1 - 2.1e-17 63.4 0.0 2.9e-17 62.9 0.0 1.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KXL42882.1 - 0.087 12.2 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase RAP80_UIM PF18282.1 KXL42883.1 - 0.0013 18.5 4.3 0.0038 17.0 4.3 1.8 1 0 0 1 1 1 1 RAP80 N-terminal ubiquitin interaction motif UIM PF02809.20 KXL42883.1 - 0.099 12.6 10.6 0.5 10.4 0.7 3.0 3 0 0 3 3 3 0 Ubiquitin interaction motif Cyclin_N PF00134.23 KXL42884.1 - 3e-06 27.0 0.0 5.2e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF4281 PF14108.6 KXL42884.1 - 0.045 14.1 0.0 0.26 11.7 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4281) MutL PF13941.6 KXL42885.1 - 0.27 9.8 0.0 0.32 9.5 0.0 1.0 1 0 0 1 1 1 0 MutL protein Acetyltransf_1 PF00583.25 KXL42886.1 - 6.6e-15 55.4 0.0 1.3e-14 54.4 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXL42886.1 - 3.2e-07 30.7 0.0 7.8e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXL42886.1 - 7.4e-07 29.0 0.0 2e-06 27.7 0.0 1.6 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.7 KXL42886.1 - 6.3e-06 26.1 0.0 1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KXL42886.1 - 0.00033 21.3 0.0 0.00045 20.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 KXL42886.1 - 0.0053 16.5 0.0 0.0091 15.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 KXL42886.1 - 0.033 14.3 0.0 0.074 13.2 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 KXL42886.1 - 0.063 12.7 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_4 PF13420.7 KXL42886.1 - 0.11 12.6 0.0 0.38 10.9 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Complex1_LYR PF05347.15 KXL42887.1 - 0.00066 19.7 0.9 0.0017 18.3 0.9 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KXL42887.1 - 0.045 14.5 1.0 2.1 9.1 0.7 2.3 2 0 0 2 2 2 0 Complex1_LYR-like VirB7 PF17413.2 KXL42887.1 - 0.077 12.3 0.1 0.17 11.2 0.1 1.6 1 0 0 1 1 1 0 Outer membrane lipoprotein virB7 FUSC PF04632.12 KXL42887.1 - 8.4 4.8 8.4 0.88 8.0 0.2 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family Ank_4 PF13637.6 KXL42888.1 - 1.3e-09 38.4 0.3 0.00016 22.2 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXL42888.1 - 4.9e-09 35.7 1.0 0.0092 16.4 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 KXL42888.1 - 1.4e-08 35.2 0.1 0.00057 20.4 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KXL42888.1 - 1.3e-06 28.6 0.8 0.013 15.9 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KXL42888.1 - 2.2e-05 24.7 0.3 2.3 8.7 0.1 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.13 KXL42888.1 - 0.00032 20.5 0.2 0.0042 16.9 0.2 2.3 1 1 0 1 1 1 1 KilA-N domain SMP PF04927.12 KXL42888.1 - 1.9 9.0 7.9 14 6.3 4.6 2.6 2 0 0 2 2 2 0 Seed maturation protein IZUMO PF15005.6 KXL42888.1 - 4.6 7.7 5.4 13 6.3 3.2 2.2 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated tRNA-synt_1c PF00749.21 KXL42889.1 - 3.9e-89 298.6 0.0 1.2e-81 274.0 0.0 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KXL42889.1 - 4.6e-29 101.5 0.0 1.2e-28 100.2 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain Macro PF01661.21 KXL42890.1 - 1.9e-40 137.6 1.2 2.8e-40 137.0 1.2 1.2 1 0 0 1 1 1 1 Macro domain AA_permease PF00324.21 KXL42891.1 - 4.2e-119 398.3 40.3 4.8e-119 398.1 40.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXL42891.1 - 1.3e-25 90.1 44.9 1.8e-25 89.7 44.9 1.0 1 0 0 1 1 1 1 Amino acid permease GCR PF02155.15 KXL42891.1 - 0.18 10.8 0.4 0.28 10.2 0.4 1.1 1 0 0 1 1 1 0 Glucocorticoid receptor Zn_clus PF00172.18 KXL42893.1 - 0.0018 18.4 12.0 0.0038 17.3 12.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.10 KXL42893.1 - 0.006 16.0 0.1 0.006 16.0 0.1 2.4 2 0 0 2 2 2 1 Histone chaperone domain CHZ PGA2 PF07543.12 KXL42893.1 - 1.1 9.3 5.7 0.53 10.3 2.7 2.0 2 0 0 2 2 2 0 Protein trafficking PGA2 Cyclin_N PF00134.23 KXL42896.1 - 7.8e-44 148.5 0.6 1.4e-43 147.7 0.2 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXL42896.1 - 5.9e-34 116.7 0.1 1.1e-33 115.8 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain adh_short_C2 PF13561.6 KXL42897.1 - 1.1e-54 185.5 1.3 1.5e-54 185.1 1.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL42897.1 - 9.8e-46 155.7 3.3 1.2e-45 155.3 3.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL42897.1 - 3.2e-13 50.0 1.2 4.2e-13 49.6 1.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL42897.1 - 0.0033 16.9 0.4 0.16 11.4 0.4 2.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TIR PF01582.20 KXL42897.1 - 0.038 13.8 0.2 0.053 13.3 0.2 1.2 1 0 0 1 1 1 0 TIR domain AdoHcyase_NAD PF00670.21 KXL42897.1 - 0.081 13.0 3.2 0.21 11.6 2.6 1.9 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain B12-binding PF02310.19 KXL42897.1 - 0.082 12.9 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 B12 binding domain SurE PF01975.17 KXL42898.1 - 1.3e-48 165.4 0.0 1.6e-48 165.1 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE PIF1 PF05970.14 KXL42899.1 - 4.3e-65 220.3 0.2 7.1e-62 209.7 0.2 2.4 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KXL42899.1 - 2.3e-24 86.2 0.0 4e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXL42899.1 - 2.8e-13 50.5 0.0 5.2e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXL42899.1 - 3e-07 30.8 0.0 1e-06 29.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KXL42899.1 - 2.5e-05 23.9 0.0 6.4e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 KXL42899.1 - 6.3e-05 23.4 0.0 0.00017 22.0 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain Herpes_Helicase PF02689.14 KXL42899.1 - 0.00013 20.0 0.1 0.00076 17.6 0.0 1.9 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.6 KXL42899.1 - 0.0006 19.6 0.0 0.0015 18.3 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KXL42899.1 - 0.001 18.8 0.0 0.5 10.1 0.1 2.7 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA PF00004.29 KXL42899.1 - 0.0012 19.3 0.0 0.0026 18.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KXL42899.1 - 0.0034 16.8 0.0 0.02 14.4 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein DUF2075 PF09848.9 KXL42899.1 - 0.0077 15.5 0.0 0.02 14.1 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) RsgA_GTPase PF03193.16 KXL42899.1 - 0.0096 15.8 0.1 0.02 14.8 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_11 PF13086.6 KXL42899.1 - 0.01 15.6 2.7 0.031 14.1 0.0 2.7 2 1 1 3 3 3 0 AAA domain T2SSE PF00437.20 KXL42899.1 - 0.013 14.6 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.14 KXL42899.1 - 0.016 15.2 0.4 0.24 11.4 0.4 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KXL42899.1 - 0.016 15.2 0.1 0.11 12.6 0.0 2.3 2 1 0 2 2 1 0 AAA domain NACHT PF05729.12 KXL42899.1 - 0.021 14.7 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 KXL42899.1 - 0.023 14.6 0.5 0.15 12.0 0.7 2.1 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea DUF5605 PF18310.1 KXL42899.1 - 0.023 14.6 0.1 0.13 12.2 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5605) TrwB_AAD_bind PF10412.9 KXL42899.1 - 0.036 13.0 0.0 0.063 12.2 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain UvrD-helicase PF00580.21 KXL42899.1 - 0.04 13.4 0.0 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain NB-ARC PF00931.22 KXL42899.1 - 0.045 12.9 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain SH3_13 PF18335.1 KXL42899.1 - 0.052 13.4 0.0 0.3 10.9 0.0 2.3 2 0 0 2 2 2 0 ATP-dependent RecD-like DNA helicase SH3 domain Helicase_RecD PF05127.14 KXL42899.1 - 0.069 13.0 0.3 0.29 11.0 0.3 2.0 1 1 0 1 1 1 0 Helicase ResIII PF04851.15 KXL42899.1 - 0.075 13.0 0.2 0.22 11.5 0.2 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit FtsK_SpoIIIE PF01580.18 KXL42899.1 - 0.076 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 KXL42899.1 - 0.086 13.2 0.0 0.22 11.9 0.0 1.7 1 1 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KXL42899.1 - 0.1 12.0 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RCC1 PF00415.18 KXL42900.1 - 6e-07 30.0 9.2 0.00076 20.0 0.2 5.2 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 KXL42900.1 - 1.5e-05 24.8 0.1 3e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 F-box-like RCC1_2 PF13540.6 KXL42900.1 - 1.6e-05 24.6 17.9 0.008 16.0 0.1 6.1 7 0 0 7 7 7 2 Regulator of chromosome condensation (RCC1) repeat F-box PF00646.33 KXL42900.1 - 0.071 13.0 0.1 0.17 11.8 0.1 1.7 1 0 0 1 1 1 0 F-box domain Rick_17kDa_Anti PF05433.15 KXL42901.1 - 4.6e-05 23.2 8.0 4.6e-05 23.2 8.0 2.5 2 0 0 2 2 2 1 Glycine zipper 2TM domain DUF533 PF04391.12 KXL42901.1 - 0.048 13.2 1.5 0.11 12.1 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF533) PseudoU_synth_2 PF00849.22 KXL42903.1 - 3.4e-30 105.2 0.0 5.5e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Auto_anti-p27 PF06677.12 KXL42903.1 - 0.061 13.5 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) T2SSG PF08334.11 KXL42903.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein G Acetyltransf_1 PF00583.25 KXL42904.1 - 3e-09 37.1 0.0 4.7e-09 36.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXL42904.1 - 1.1e-08 35.3 0.0 2e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXL42904.1 - 1.6e-08 34.6 0.0 2.8e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXL42904.1 - 3.6e-05 23.6 0.0 6.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KXL42904.1 - 0.00016 21.7 0.0 0.00031 20.8 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KXL42904.1 - 0.00041 20.4 0.0 0.11 12.6 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 KXL42904.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GFO_IDH_MocA PF01408.22 KXL42905.1 - 1.2e-16 61.6 0.0 1.8e-16 61.1 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXL42905.1 - 2.7e-07 30.6 0.0 4.3e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DEP PF00610.21 KXL42905.1 - 0.069 13.2 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Dimer_Tnp_hAT PF05699.14 KXL42906.1 - 0.026 14.3 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region RNA_pol_Rpb2_6 PF00562.28 KXL42907.1 - 3.7e-114 381.8 0.1 4.7e-114 381.5 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KXL42907.1 - 1e-32 113.3 0.0 1.6e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 KXL42907.1 - 3.4e-28 97.6 0.0 8.3e-28 96.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 KXL42907.1 - 4.3e-25 88.5 0.0 8.8e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 KXL42907.1 - 1.3e-23 82.7 0.0 2.5e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 KXL42907.1 - 2.2e-15 56.8 0.3 1.8e-14 53.9 0.0 2.4 2 1 0 2 2 2 1 RNA polymerase Rpb2, domain 7 zf-RING_12 PF17976.1 KXL42907.1 - 0.045 14.0 0.2 0.13 12.5 0.2 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Oxidored_nitro PF00148.19 KXL42908.1 - 0.073 11.8 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase tRNA-synt_1c PF00749.21 KXL42908.1 - 0.14 11.1 1.0 0.57 9.0 0.0 2.0 1 1 1 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain WW PF00397.26 KXL42909.1 - 2.3e-05 24.4 1.6 2.3e-05 24.4 1.6 2.2 2 0 0 2 2 2 1 WW domain DUF2076 PF09849.9 KXL42909.1 - 0.049 13.7 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) TFIID_20kDa PF03847.13 KXL42910.1 - 1.3e-21 76.9 0.1 1.7e-21 76.5 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 KXL42910.1 - 0.053 13.8 0.0 0.077 13.3 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-18kDa PF02269.16 KXL42910.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Pkinase PF00069.25 KXL42911.1 - 3.4e-43 147.9 0.0 1.3e-21 77.2 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXL42911.1 - 2.3e-12 46.7 0.0 3.2e-08 33.2 0.0 3.6 3 1 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXL42911.1 - 0.00013 20.9 0.0 0.00052 18.9 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KXL42911.1 - 0.00073 19.5 0.0 0.042 13.8 0.0 2.5 1 1 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 KXL42911.1 - 0.0076 15.9 0.0 0.11 12.1 0.0 2.6 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KXL42911.1 - 0.015 14.6 0.0 0.036 13.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXL42911.1 - 0.21 10.9 0.0 4.7 6.4 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Cnd1 PF12717.7 KXL42912.1 - 9.8e-48 162.2 3.7 6.3e-42 143.4 0.2 4.1 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 KXL42912.1 - 1.7e-37 128.8 0.0 1e-36 126.3 0.0 2.4 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.6 KXL42912.1 - 8.7e-09 35.7 4.4 0.12 12.7 0.1 5.8 5 1 1 6 6 6 3 HEAT repeats HEAT PF02985.22 KXL42912.1 - 5.6e-05 23.0 9.8 0.5 10.8 0.0 7.8 8 1 1 9 9 9 1 HEAT repeat RTP1_C1 PF10363.9 KXL42912.1 - 0.00081 19.5 0.3 0.17 12.1 0.0 3.3 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 KXL42912.1 - 0.0023 16.6 4.7 0.21 10.1 0.3 3.0 2 1 0 2 2 2 2 Adaptin N terminal region ADH_N_2 PF16884.5 KXL42914.1 - 0.0029 17.5 0.0 0.0031 17.4 0.0 1.1 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_N PF08240.12 KXL42914.1 - 0.029 14.3 0.0 0.039 13.8 0.0 1.2 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain RCR PF12273.8 KXL42916.1 - 5.5e-17 62.5 6.4 7.6e-17 62.1 6.4 1.3 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Rhabdo_glycop PF00974.18 KXL42916.1 - 0.02 13.4 0.5 0.025 13.0 0.5 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Hum_adeno_E3A PF05393.11 KXL42916.1 - 0.058 13.4 0.6 0.086 12.8 0.6 1.2 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein LapA_dom PF06305.11 KXL42916.1 - 0.83 9.5 2.1 1.2 9.0 2.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Arf PF00025.21 KXL42918.1 - 4.1e-43 146.9 0.0 4.5e-43 146.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KXL42918.1 - 8.3e-20 71.0 0.0 9.3e-20 70.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXL42918.1 - 1.7e-16 60.5 0.0 2.7e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KXL42918.1 - 9.2e-09 35.0 0.0 1e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KXL42918.1 - 8.4e-08 31.8 0.0 1e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXL42918.1 - 1.2e-07 31.9 0.0 1.7e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KXL42918.1 - 0.00014 21.1 0.3 0.00037 19.8 0.1 1.7 2 0 0 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.27 KXL42918.1 - 0.0029 17.2 0.0 0.015 14.9 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KXL42918.1 - 0.0082 16.2 0.0 0.32 11.1 0.1 2.1 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.18 KXL42918.1 - 0.009 15.6 0.3 0.028 13.9 0.3 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 KXL42918.1 - 0.029 14.4 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain NACHT PF05729.12 KXL42918.1 - 0.21 11.5 0.7 0.44 10.5 0.0 1.9 2 0 0 2 2 2 0 NACHT domain Adaptin_N PF01602.20 KXL42919.1 - 1.2e-138 463.0 0.5 1.5e-138 462.7 0.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KXL42919.1 - 2.2e-66 222.9 0.2 5.6e-62 208.6 0.0 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXL42919.1 - 9.8e-17 61.1 0.8 3.1e-06 27.5 0.0 5.5 3 2 3 6 6 6 4 HEAT repeats HEAT PF02985.22 KXL42919.1 - 1.2e-13 50.0 1.6 0.0092 16.2 0.0 6.8 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 KXL42919.1 - 2.5e-05 24.7 0.5 0.92 10.1 0.0 5.8 6 1 1 7 7 7 1 HEAT-like repeat Arm PF00514.23 KXL42919.1 - 0.023 14.7 1.1 73 3.6 0.0 5.2 5 1 1 6 6 6 0 Armadillo/beta-catenin-like repeat UNC45-central PF11701.8 KXL42919.1 - 0.024 14.6 0.1 1.2 9.0 0.0 2.6 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 KXL42919.1 - 0.025 14.2 0.3 0.99 8.9 0.0 3.3 3 1 1 4 4 4 0 CLASP N terminal DUF2514 PF10721.9 KXL42919.1 - 0.055 13.5 2.0 0.1 12.6 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) ADH_zinc_N PF00107.26 KXL42920.1 - 1.6e-11 44.3 0.0 2.5e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXL42920.1 - 6.6e-05 22.8 0.6 0.0024 17.8 0.2 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXL42920.1 - 0.00072 20.6 0.0 0.0012 19.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF5310 PF17237.2 KXL42921.1 - 1.7e-21 75.8 1.1 1.9e-21 75.6 1.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5310) Cpn60_TCP1 PF00118.24 KXL42925.1 - 2.8e-153 511.1 5.6 3.2e-153 510.9 5.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PNTB_4TM PF12769.7 KXL42925.1 - 0.16 12.5 0.3 0.67 10.5 0.0 2.2 3 0 0 3 3 3 0 4TM region of pyridine nucleotide transhydrogenase, mitoch Pyridoxal_deC PF00282.19 KXL42926.1 - 4.2e-75 252.8 0.0 6.6e-74 248.9 0.0 2.2 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain PUF PF00806.19 KXL42926.1 - 1.6e-12 46.4 0.0 4.1 7.3 0.0 7.7 7 0 0 7 7 7 5 Pumilio-family RNA binding repeat Beta_elim_lyase PF01212.21 KXL42926.1 - 9.4e-10 38.2 0.0 1.7e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KXL42926.1 - 4e-05 22.7 0.0 6.8e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DUF1722 PF08349.11 KXL42926.1 - 0.085 13.1 0.2 0.46 10.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) SepSecS PF05889.13 KXL42926.1 - 0.11 11.2 0.0 0.2 10.3 0.0 1.3 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS OTU PF02338.19 KXL42927.1 - 1.3e-06 28.9 0.0 2.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Bromodomain PF00439.25 KXL42928.1 - 4.8e-36 122.7 3.7 6e-18 64.7 0.1 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 KXL42928.1 - 8.9e-18 64.3 0.3 2e-17 63.2 0.3 1.6 1 0 0 1 1 1 1 BAH domain CENP-B_dimeris PF09026.10 KXL42928.1 - 4.4 7.8 16.3 14 6.2 16.3 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PRCC PF10253.9 KXL42928.1 - 6.3 7.5 17.9 3.1 8.5 11.5 3.0 2 1 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting AMMECR1 PF01871.17 KXL42929.1 - 8.4e-42 142.6 0.0 1.3e-41 142.0 0.0 1.4 1 0 0 1 1 1 1 AMMECR1 Helicase_C_4 PF13871.6 KXL42929.1 - 0.14 11.8 1.0 0.23 11.1 1.0 1.2 1 0 0 1 1 1 0 C-terminal domain on Strawberry notch homologue PI3K_1B_p101 PF10486.9 KXL42929.1 - 0.19 9.5 3.8 0.24 9.1 3.8 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CXCR4_N PF12109.8 KXL42930.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 CXCR4 Chemokine receptor N terminal HSP9_HSP12 PF04119.12 KXL42931.1 - 3.3e-22 78.6 15.1 3.3e-22 78.6 15.1 1.7 1 1 0 1 1 1 1 Heat shock protein 9/12 YtxH PF12732.7 KXL42931.1 - 0.34 11.5 2.8 0.76 10.4 2.8 1.7 1 1 0 1 1 1 0 YtxH-like protein Aldolase_II PF00596.21 KXL42932.1 - 3.3e-41 141.3 0.1 4.9e-41 140.7 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Sugar_tr PF00083.24 KXL42933.1 - 2.9e-119 398.9 15.7 5.4e-119 398.0 15.7 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL42933.1 - 2.3e-26 92.6 47.7 4.9e-25 88.2 28.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Lactamase_B PF00753.27 KXL42934.1 - 4.5e-20 72.5 0.2 8.2e-13 48.8 0.0 2.2 1 1 1 2 2 2 2 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 KXL42934.1 - 8.2e-20 70.5 0.0 1.7e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 KXL42934.1 - 1.3e-06 28.1 0.0 3.4e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXL42934.1 - 0.0008 19.3 0.0 0.002 18.1 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 KXL42934.1 - 0.0096 15.4 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CSD2 PF17876.1 KXL42934.1 - 0.096 12.9 0.4 2.9 8.1 0.2 2.5 1 1 1 2 2 2 0 Cold shock domain RRM_1 PF00076.22 KXL42935.1 - 2.7e-08 33.5 0.0 5.9e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXL42935.1 - 1e-05 25.1 0.0 2.7e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RF-1 PF00472.20 KXL42936.1 - 5.2e-20 71.5 0.6 8.1e-20 70.9 0.6 1.2 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.9 KXL42936.1 - 0.0032 17.9 0.0 0.0052 17.2 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein HLH PF00010.26 KXL42936.1 - 0.051 13.6 0.4 0.2 11.7 0.0 2.2 2 1 0 2 2 2 0 Helix-loop-helix DNA-binding domain Pro-kuma_activ PF09286.11 KXL42937.1 - 3.6e-41 140.8 0.4 1e-40 139.4 0.3 1.8 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KXL42937.1 - 0.00059 19.2 0.1 0.0011 18.3 0.1 1.4 1 0 0 1 1 1 1 Subtilase family CHS5_N PF16892.5 KXL42938.1 - 0.1 12.5 0.2 0.2 11.6 0.2 1.5 1 1 0 1 1 1 0 Chitin biosynthesis protein CHS5 N-terminus MT0933_antitox PF14013.6 KXL42939.1 - 6.5e-06 26.3 2.4 0.012 15.8 0.6 2.1 2 0 0 2 2 2 2 MT0933-like antitoxin protein HSP9_HSP12 PF04119.12 KXL42939.1 - 0.034 14.5 1.6 0.048 14.1 1.4 1.4 1 1 0 1 1 1 0 Heat shock protein 9/12 EF-hand_7 PF13499.6 KXL42941.1 - 0.00064 20.1 0.5 0.038 14.4 0.2 4.0 2 1 1 3 3 3 2 EF-hand domain pair SH3_15 PF18346.1 KXL42941.1 - 0.025 14.9 0.6 1.9 8.9 0.0 3.7 3 0 0 3 3 3 0 Mind bomb SH3 repeat domain EF-hand_6 PF13405.6 KXL42941.1 - 0.22 11.6 6.0 3 8.0 0.1 4.4 5 0 0 5 5 5 0 EF-hand domain EF-hand_1 PF00036.32 KXL42941.1 - 1.2 8.9 9.0 0.75 9.5 0.2 4.3 4 0 0 4 4 4 0 EF hand Leader_CPA1 PF08252.11 KXL42942.1 - 0.088 12.2 1.4 0.18 11.3 1.4 1.5 1 0 0 1 1 1 0 arg-2/CPA1 leader peptide RINT1_TIP1 PF04437.13 KXL42943.1 - 1.1e-175 585.3 0.0 1.1e-175 585.3 0.0 2.0 2 0 0 2 2 2 1 RINT-1 / TIP-1 family ADIP PF11559.8 KXL42943.1 - 0.013 15.6 9.4 0.15 12.1 10.8 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3371 PF11851.8 KXL42943.1 - 0.2 12.7 2.4 0.8 10.8 2.4 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) RdRP PF05183.12 KXL42944.1 - 5.1e-171 570.3 0.0 6.3e-171 570.0 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.22 KXL42944.1 - 0.0018 18.0 0.0 0.0058 16.4 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) T4SS_TraI PF16932.5 KXL42944.1 - 0.053 12.7 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Type IV secretory system, conjugal DNA-protein transfer Metallopep PF12044.8 KXL42945.1 - 4.2e-170 566.0 0.0 5.2e-170 565.7 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 KXL42945.1 - 0.0011 18.9 0.0 0.011 15.7 0.0 2.1 1 1 1 2 2 2 2 Jacalin-like lectin domain Whi5 PF08528.11 KXL42946.1 - 1.2e-08 34.4 0.0 2.2e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Whi5 like Aminotran_1_2 PF00155.21 KXL42947.1 - 3.3e-32 112.0 0.0 4.4e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KXL42947.1 - 0.12 10.9 0.0 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme MARVEL PF01284.23 KXL42948.1 - 0.0025 17.8 11.0 0.0064 16.5 11.0 1.6 1 1 0 1 1 1 1 Membrane-associating domain SpoIIM PF01944.17 KXL42948.1 - 2.5 8.1 16.3 2.1 8.4 11.7 2.2 2 0 0 2 2 2 0 Stage II sporulation protein M Cupin_1 PF00190.22 KXL42949.1 - 1.9e-37 128.2 0.0 1.2e-17 63.9 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KXL42949.1 - 5.1e-24 83.8 1.4 2.2e-11 43.3 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KXL42949.1 - 7.8e-11 41.5 0.0 3.7e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KXL42949.1 - 3.1e-07 30.4 0.4 5.6e-05 23.1 0.1 2.5 2 0 0 2 2 2 1 AraC-like ligand binding domain CENP-C_C PF11699.8 KXL42949.1 - 0.00026 21.1 0.0 0.042 14.1 0.0 2.5 2 0 0 2 2 2 1 Mif2/CENP-C like BiPBP_C PF06832.12 KXL42949.1 - 0.048 13.7 0.1 4.5 7.4 0.0 2.6 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family ARD PF03079.14 KXL42949.1 - 0.065 13.4 0.2 0.29 11.3 0.0 1.9 2 0 0 2 2 2 0 ARD/ARD' family 3-HAO PF06052.12 KXL42949.1 - 0.087 12.5 0.0 2.9 7.5 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase MannoseP_isomer PF01050.18 KXL42949.1 - 0.14 12.0 0.0 2.6 7.9 0.0 2.1 2 0 0 2 2 2 0 Mannose-6-phosphate isomerase DUF1275 PF06912.11 KXL42950.1 - 8.1e-47 159.6 12.8 9.5e-47 159.4 12.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) CitMHS PF03600.16 KXL42950.1 - 0.03 13.5 4.0 0.041 13.1 4.0 1.3 1 0 0 1 1 1 0 Citrate transporter DUF202 PF02656.15 KXL42950.1 - 3.2 8.3 7.3 2.5 8.6 1.8 3.2 2 2 0 2 2 2 0 Domain of unknown function (DUF202) DUF2370 PF10176.9 KXL42951.1 - 2.9e-85 285.5 0.0 5e-85 284.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) N6-adenineMlase PF10237.9 KXL42952.1 - 2.7e-53 180.1 0.0 3.5e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Piezo_RRas_bdg PF12166.8 KXL42954.1 - 0.092 12.0 0.7 1.3 8.3 0.2 2.0 2 0 0 2 2 2 0 Piezo non-specific cation channel, R-Ras-binding domain RRM_1 PF00076.22 KXL42955.1 - 2.4e-19 68.9 0.0 1.5e-13 50.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PCEMA1 PF07418.11 KXL42955.1 - 0.011 15.3 0.1 0.016 14.7 0.1 1.2 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 DUF4407 PF14362.6 KXL42955.1 - 3 7.1 9.9 4.7 6.5 9.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sec34 PF04136.15 KXL42956.1 - 1.8e-49 167.5 0.6 2.9e-49 166.8 0.6 1.4 1 0 0 1 1 1 1 Sec34-like family Phasin_2 PF09361.10 KXL42956.1 - 0.061 13.6 0.6 0.23 11.8 0.6 2.0 1 0 0 1 1 1 0 Phasin protein Exo70 PF03081.15 KXL42956.1 - 0.32 10.0 1.7 12 4.9 0.0 3.0 2 1 1 3 3 3 0 Exo70 exocyst complex subunit CLN3 PF02487.17 KXL42957.1 - 1.1e-153 512.0 7.2 1.3e-153 511.8 7.2 1.0 1 0 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 KXL42957.1 - 0.023 13.6 33.2 0.49 9.3 31.1 2.8 1 1 0 1 1 1 0 Major Facilitator Superfamily Rxt3 PF08642.10 KXL42959.1 - 1.1e-33 116.8 0.1 4.3e-33 114.8 0.1 2.0 1 1 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 KXL42959.1 - 1.7e-05 24.9 0.0 9.2e-05 22.5 0.0 2.1 3 0 0 3 3 3 1 LCCL domain Cupin_2 PF07883.11 KXL42960.1 - 2.9e-07 30.1 0.0 5.1e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KXL42960.1 - 0.0015 18.2 0.0 0.0047 16.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF861) CtaG_Cox11 PF04442.14 KXL42961.1 - 7.4e-58 194.9 0.0 1.2e-57 194.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DUF2336 PF10098.9 KXL42961.1 - 0.055 12.9 0.2 0.074 12.5 0.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2336) DDE_Tnp_1_7 PF13843.6 KXL42964.1 - 1.3e-23 83.9 0.0 1.4e-23 83.8 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 STIMATE PF12400.8 KXL42965.1 - 1.1e-38 132.6 4.6 1.1e-38 132.6 4.6 1.5 2 0 0 2 2 2 1 STIMATE family FKBP_C PF00254.28 KXL42965.1 - 6.8e-29 100.0 0.0 1.1e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Csm1_N PF18504.1 KXL42968.1 - 0.084 13.2 9.5 0.13 12.6 8.8 1.7 1 1 1 2 2 2 0 Csm1 N-terminal domain HIP1_clath_bdg PF16515.5 KXL42968.1 - 0.11 13.1 10.1 0.2 12.3 10.1 1.5 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Zn_clus PF00172.18 KXL42968.1 - 0.2 11.8 9.7 0.34 11.1 1.6 2.2 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Atg14 PF10186.9 KXL42968.1 - 0.67 9.0 12.4 0.77 8.8 12.4 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Phage_Gp23 PF10669.9 KXL42968.1 - 4.6 7.6 9.1 6.6 7.1 8.2 1.6 1 1 1 2 2 2 0 Protein gp23 (Bacteriophage A118) TPX2 PF06886.11 KXL42968.1 - 5.8 7.2 25.4 4.6 7.6 2.6 3.2 1 1 2 3 3 3 0 Targeting protein for Xklp2 (TPX2) SHMT PF00464.19 KXL42972.1 - 4.5e-204 677.5 0.0 5.3e-204 677.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 KXL42972.1 - 5.4e-06 25.8 0.0 1.1e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KXL42972.1 - 8.8e-06 24.9 0.0 1.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Pyridoxal_deC PF00282.19 KXL42972.1 - 0.055 12.2 0.0 0.12 11.1 0.0 1.6 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain CheZ PF04344.13 KXL42973.1 - 0.0043 17.0 0.3 0.0082 16.1 0.1 1.6 1 1 0 1 1 1 1 Chemotaxis phosphatase, CheZ D-ser_dehydrat PF14031.6 KXL42975.1 - 2.3e-22 79.5 0.0 5.4e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 KXL42975.1 - 6e-13 49.0 0.0 8.7e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DUF2119 PF09892.9 KXL42975.1 - 0.007 15.8 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2119) TPR_12 PF13424.6 KXL42975.1 - 0.19 12.0 0.1 28 5.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat THUMP PF02926.17 KXL42976.1 - 2.2e-09 37.6 0.1 3.4e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 THUMP domain APH PF01636.23 KXL42977.1 - 3.9e-07 30.2 0.0 6.1e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family MFS_1 PF07690.16 KXL42978.1 - 5.7e-34 117.6 33.6 5.7e-34 117.6 33.6 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Cornichon PF03311.14 KXL42978.1 - 0.092 13.1 0.6 1 9.7 0.1 2.4 2 0 0 2 2 2 0 Cornichon protein Thioredoxin PF00085.20 KXL42979.1 - 1.5e-65 217.6 2.4 2.7e-31 107.6 0.0 4.3 4 1 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 KXL42979.1 - 9.5e-49 165.8 0.3 1.8e-36 125.8 0.2 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain Calsequestrin PF01216.17 KXL42979.1 - 7.3e-13 48.3 0.8 7.3e-13 48.3 0.8 1.7 2 0 0 2 2 2 1 Calsequestrin Thioredoxin_8 PF13905.6 KXL42979.1 - 3.8e-09 36.8 0.0 0.027 14.8 0.0 5.0 4 1 1 5 5 5 2 Thioredoxin-like OST3_OST6 PF04756.13 KXL42979.1 - 1.1e-07 31.6 0.1 0.042 13.2 0.0 3.2 2 1 1 3 3 3 3 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KXL42979.1 - 1.1e-07 32.2 0.3 0.0078 16.7 0.0 3.2 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KXL42979.1 - 8.1e-07 29.1 0.0 0.015 15.4 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 KXL42979.1 - 4.2e-06 26.7 0.6 0.061 13.3 0.0 3.2 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.10 KXL42979.1 - 0.0013 18.4 0.7 0.22 11.3 0.0 3.1 3 0 0 3 3 3 1 Redoxin DUF723 PF05265.13 KXL42979.1 - 0.052 13.5 0.9 0.45 10.5 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF723) YtxH PF12732.7 KXL42979.1 - 1.5 9.4 8.0 6.2 7.4 0.4 3.7 3 1 0 3 3 3 0 YtxH-like protein Methyltransf_25 PF13649.6 KXL42980.1 - 8.9e-12 45.6 0.1 1.9e-11 44.5 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL42980.1 - 1.5e-09 38.4 0.0 2.8e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL42980.1 - 3.3e-09 36.7 0.0 4.9e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL42980.1 - 5.9e-08 33.4 0.0 2.1e-07 31.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXL42980.1 - 0.0014 18.5 0.0 0.002 18.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXL42980.1 - 0.0019 18.0 0.0 0.0029 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 KXL42980.1 - 0.01 15.4 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.7 KXL42980.1 - 0.02 14.8 0.0 0.03 14.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 KXL42980.1 - 0.053 12.8 0.0 0.075 12.3 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase zf-rbx1 PF12678.7 KXL42981.1 - 6.5e-08 32.8 4.7 2.1e-07 31.1 4.7 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KXL42981.1 - 7.3e-08 32.6 1.4 7.3e-08 32.6 1.4 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KXL42981.1 - 0.0001 22.1 1.1 0.00023 21.0 1.1 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXL42981.1 - 0.00019 21.3 3.5 0.00053 19.9 3.6 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXL42981.1 - 0.00019 21.2 4.5 0.00048 19.9 1.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXL42981.1 - 0.0002 21.2 2.1 0.00051 19.8 2.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXL42981.1 - 0.00086 19.1 0.5 0.00086 19.1 0.5 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KXL42981.1 - 0.00086 18.9 0.6 0.002 17.7 0.6 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 KXL42981.1 - 0.0014 18.6 0.9 0.0039 17.2 0.9 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KXL42981.1 - 0.0092 16.0 1.3 0.013 15.5 0.3 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KXL42981.1 - 0.041 13.7 0.7 0.1 12.4 0.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 KXL42981.1 - 0.11 12.9 0.6 0.22 11.9 0.6 1.5 1 0 0 1 1 1 0 RING-like domain zinc_ribbon_16 PF17034.5 KXL42981.1 - 0.27 11.5 1.1 0.37 11.0 0.1 1.7 2 0 0 2 2 1 0 Zinc-ribbon like family zf-P11 PF03854.14 KXL42981.1 - 4.8 6.9 7.2 0.42 10.3 2.1 1.8 2 0 0 2 2 2 0 P-11 zinc finger F-box PF00646.33 KXL42982.1 - 1.2e-05 25.0 0.0 3.4e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXL42982.1 - 0.0031 17.4 0.0 0.0078 16.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like DIOX_N PF14226.6 KXL42983.1 - 0.14 12.9 0.0 0.25 12.1 0.0 1.4 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal Glyco_hydro_32N PF00251.20 KXL42984.1 - 1.9e-77 260.8 6.3 3.5e-77 260.0 6.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KXL42984.1 - 3.8e-09 36.7 0.1 6.5e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Enolase_C PF00113.22 KXL42985.1 - 2.8e-115 384.6 0.0 3.6e-115 384.3 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KXL42985.1 - 8.3e-49 165.1 0.1 1.4e-48 164.4 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KXL42985.1 - 9.3e-07 28.6 0.0 1.5e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like Abhydrolase_3 PF07859.13 KXL42987.1 - 3.4e-46 157.8 0.0 4.2e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXL42987.1 - 4.1e-12 45.7 0.1 9e-12 44.6 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 KXL42987.1 - 0.0012 19.5 0.1 0.0028 18.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXL42987.1 - 0.016 14.7 0.1 0.04 13.4 0.1 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family Methyltransf_23 PF13489.6 KXL42988.1 - 2.5e-19 69.7 0.0 3.3e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL42988.1 - 2.2e-10 41.1 0.0 4.5e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL42988.1 - 2.5e-09 37.7 0.0 4.2e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL42988.1 - 1e-06 28.6 0.0 8.2e-06 25.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL42988.1 - 1.1e-06 29.3 0.0 2.9e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXL42988.1 - 0.015 14.7 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KXL42988.1 - 0.07 12.5 0.0 1.1 8.5 0.0 2.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXL42988.1 - 0.2 11.2 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Herpes_gE PF02480.16 KXL42989.1 - 0.28 9.9 0.0 0.35 9.6 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E PsbW PF07123.12 KXL42990.1 - 0.13 12.3 1.2 0.16 12.0 0.2 1.7 2 0 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) Peroxidase_2 PF01328.17 KXL42991.1 - 2.5e-46 158.6 0.0 3.4e-46 158.1 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 LMWPc PF01451.21 KXL42993.1 - 1.4e-31 109.8 0.0 2.2e-31 109.2 0.0 1.3 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase PS_Dcarbxylase PF02666.15 KXL42994.1 - 1.1e-79 266.6 0.0 1.2e-57 194.8 0.0 2.1 2 0 0 2 2 2 2 Phosphatidylserine decarboxylase DUF885 PF05960.11 KXL42995.1 - 2.4e-43 149.6 5.3 2.6e-42 146.2 5.3 2.0 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF885) Rx_N PF18052.1 KXL42996.1 - 0.0078 16.5 0.0 0.026 14.8 0.0 1.8 2 0 0 2 2 2 1 Rx N-terminal domain ubiquitin PF00240.23 KXL42996.1 - 0.19 11.5 0.0 0.4 10.5 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family DUF2407 PF10302.9 KXL42996.1 - 0.2 12.3 1.1 0.6 10.7 0.0 2.4 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain p450 PF00067.22 KXL42997.1 - 0.0033 16.2 0.0 0.0049 15.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KXL42998.1 - 2.6e-42 145.2 0.0 3.5e-41 141.4 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 AcrZ PF10766.9 KXL42999.1 - 0.079 12.5 0.7 0.65 9.6 0.1 2.5 2 0 0 2 2 2 0 Multidrug efflux pump-associated protein AcrZ AA_permease_2 PF13520.6 KXL43000.1 - 7.9e-40 137.0 43.9 9.6e-40 136.7 43.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXL43000.1 - 1.2e-09 37.3 33.6 1.7e-09 36.8 33.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2715 PF10895.8 KXL43000.1 - 0.0082 15.8 2.3 0.032 13.9 0.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF2715) CENP-K PF11802.8 KXL43001.1 - 0.017 14.7 9.0 0.73 9.4 0.1 2.4 1 1 1 2 2 2 0 Centromere-associated protein K DUF4140 PF13600.6 KXL43001.1 - 0.024 15.1 4.5 0.024 15.1 4.5 3.8 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) UPF0184 PF03670.13 KXL43001.1 - 0.27 11.6 4.2 0.3 11.5 1.0 2.7 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) IMD PF08397.11 KXL43001.1 - 1.9 7.8 21.2 2.5 7.4 10.1 2.8 1 1 1 2 2 2 0 IRSp53/MIM homology domain Laminin_II PF06009.12 KXL43001.1 - 7.8 6.5 16.4 0.56 10.2 7.3 2.4 1 1 1 2 2 2 0 Laminin Domain II Glyco_hydro_76 PF03663.14 KXL43002.1 - 1.9e-155 517.9 26.7 2.2e-155 517.7 26.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KXL43002.1 - 0.0013 17.8 10.0 0.0028 16.8 0.5 3.0 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 AA_permease PF00324.21 KXL43003.1 - 8.4e-125 417.1 38.3 1e-124 416.8 38.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXL43003.1 - 9.7e-43 146.6 37.7 1.3e-42 146.2 37.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1690 PF07956.11 KXL43004.1 - 7.8e-35 120.3 8.3 1.2e-33 116.5 8.3 2.0 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) Tup_N PF08581.10 KXL43004.1 - 0.033 14.5 1.7 15 5.9 0.1 3.1 3 0 0 3 3 3 0 Tup N-terminal Acetyltransf_1 PF00583.25 KXL43005.1 - 2.1e-09 37.6 0.0 2.8e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXL43005.1 - 2.2e-05 24.8 0.0 3.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXL43005.1 - 2.5e-05 24.2 0.0 3.3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KXL43005.1 - 0.0009 19.9 0.0 0.0015 19.2 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXL43005.1 - 0.069 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein CorA PF01544.18 KXL43006.1 - 4.7e-10 39.3 0.1 8.9e-10 38.4 0.1 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Phage_holin_3_6 PF07332.11 KXL43006.1 - 0.045 13.8 2.3 0.096 12.7 2.3 1.5 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4199 PF13858.6 KXL43006.1 - 0.058 13.8 0.5 0.099 13.0 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) ApoL PF05461.11 KXL43006.1 - 0.085 12.2 2.1 0.15 11.3 1.7 1.5 1 1 1 2 2 2 0 Apolipoprotein L DUF3696 PF12476.8 KXL43007.1 - 0.023 15.1 0.0 0.041 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3696) Pkinase PF00069.25 KXL43008.1 - 1.5e-60 204.8 0.0 1.2e-37 129.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXL43008.1 - 1.2e-27 96.9 0.0 5.3e-20 71.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 KXL43008.1 - 2.2e-13 50.4 0.1 4.7e-13 49.3 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 KXL43008.1 - 3.3e-08 33.2 0.0 7.3e-06 25.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like PAS PF00989.25 KXL43008.1 - 9.4e-07 28.8 0.0 2.1e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold APH PF01636.23 KXL43008.1 - 4.9e-05 23.4 1.3 0.002 18.1 0.2 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KXL43008.1 - 0.00041 19.8 0.1 0.0008 18.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXL43008.1 - 0.0044 16.0 0.0 0.0044 16.0 0.0 1.8 2 0 0 2 2 2 1 Haspin like kinase domain FTA2 PF13095.6 KXL43008.1 - 0.0059 16.2 0.3 2 8.0 0.1 2.4 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 PAS_9 PF13426.7 KXL43008.1 - 0.057 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 PAS domain PAS_4 PF08448.10 KXL43008.1 - 0.079 13.2 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 PAS fold RIO1 PF01163.22 KXL43008.1 - 0.14 11.8 1.7 0.19 11.3 0.1 2.0 2 0 0 2 2 2 0 RIO1 family Seadorna_VP7 PF07387.11 KXL43008.1 - 0.25 10.4 0.0 0.43 9.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 RNA_pol_Rpb4 PF03874.16 KXL43009.1 - 2.6e-20 73.0 0.0 3.4e-20 72.6 0.0 1.2 1 1 0 1 1 1 1 RNA polymerase Rpb4 RhoGAP PF00620.27 KXL43010.1 - 4e-38 130.6 0.1 9.2e-38 129.4 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 KXL43010.1 - 1.4e-26 92.4 38.8 1.6e-11 44.2 4.1 4.7 5 0 0 5 5 5 4 LIM domain Questin_oxidase PF14027.6 KXL43012.1 - 9.2e-94 314.8 1.3 1.1e-93 314.5 1.3 1.1 1 0 0 1 1 1 1 Questin oxidase-like SAM_KSR1 PF13543.6 KXL43013.1 - 0.014 15.5 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 PhoLip_ATPase_C PF16212.5 KXL43015.1 - 1.6e-77 260.7 26.8 1.6e-77 260.7 26.8 2.0 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KXL43015.1 - 5e-18 64.6 0.1 1.5e-17 63.0 0.1 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KXL43015.1 - 3.9e-13 50.2 3.1 5.6e-09 36.6 1.1 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXL43015.1 - 2.3e-11 43.6 0.0 7.5e-11 42.0 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KXL43015.1 - 0.00021 20.8 0.0 0.0018 17.8 0.0 2.5 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KXL43015.1 - 0.017 14.9 0.5 0.065 13.0 0.9 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase PHD PF00628.29 KXL43016.1 - 0.00091 19.1 11.3 0.0017 18.2 11.3 1.5 1 0 0 1 1 1 1 PHD-finger DUF5427 PF10310.9 KXL43016.1 - 0.11 11.4 7.4 0.23 10.3 7.4 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SpoIIE PF07228.12 KXL43017.1 - 4.8e-11 42.9 1.2 2.4e-10 40.6 1.2 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 KXL43017.1 - 3.7e-09 36.6 0.1 0.00026 20.7 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KXL43017.1 - 0.0032 17.2 1.5 0.014 15.0 1.5 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C RRM_1 PF00076.22 KXL43019.1 - 3e-41 139.1 0.0 2.5e-19 68.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXL43019.1 - 0.00011 22.2 0.0 0.59 10.3 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 KXL43019.1 - 0.0012 18.4 0.0 0.0039 16.8 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3784 PF12650.7 KXL43023.1 - 0.021 15.0 1.4 0.021 15.0 1.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF3096 PF11295.8 KXL43023.1 - 0.03 14.0 5.4 0.1 12.3 5.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3096) HWE_HK PF07536.14 KXL43024.1 - 0.19 12.4 2.6 0.46 11.2 0.6 2.4 2 0 0 2 2 2 0 HWE histidine kinase SEN1_N PF12726.7 KXL43025.1 - 8.7e-166 553.3 7.7 1.2e-165 552.8 7.7 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 KXL43025.1 - 8.6e-73 245.3 1.0 8.6e-73 245.3 1.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.6 KXL43025.1 - 1.1e-59 201.5 0.0 2.5e-59 200.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXL43025.1 - 4.9e-09 36.2 0.3 1.4e-05 24.9 0.1 2.7 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.21 KXL43025.1 - 1.4e-07 31.3 0.1 6.3e-05 22.7 0.0 3.2 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 KXL43025.1 - 2.3e-07 31.3 0.0 1.3e-06 28.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KXL43025.1 - 0.0039 17.0 0.8 0.52 10.0 0.1 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KXL43025.1 - 0.055 13.5 0.1 0.43 10.6 0.1 2.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Sugar_tr PF00083.24 KXL43027.1 - 4.2e-07 29.2 2.3 4.9e-07 29.0 2.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter SKG6 PF08693.10 KXL43027.1 - 3.5 7.1 5.8 0.38 10.2 1.1 1.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain CDPS PF16715.5 KXL43028.1 - 0.24 11.0 0.0 0.34 10.5 0.0 1.2 1 0 0 1 1 1 0 Cyclodipeptide synthase Tyr-DNA_phospho PF06087.12 KXL43029.1 - 4.2e-84 282.9 0.0 5e-84 282.6 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 KXL43029.1 - 0.00063 19.6 0.0 0.01 15.7 0.0 2.3 2 0 0 2 2 2 1 PLD-like domain UIM PF02809.20 KXL43029.1 - 0.0067 16.3 0.4 0.022 14.7 0.4 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif Pyridoxal_deC PF00282.19 KXL43030.1 - 6.9e-106 354.1 0.0 9.4e-106 353.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Sugar_tr PF00083.24 KXL43031.1 - 1.8e-70 238.1 18.3 2.1e-70 237.9 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL43031.1 - 2.1e-19 69.7 32.6 4.6e-19 68.6 18.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GATA PF00320.27 KXL43032.1 - 1.3e-05 24.7 1.8 0.042 13.5 0.3 2.5 2 0 0 2 2 2 2 GATA zinc finger PQ-loop PF04193.14 KXL43034.1 - 5.6e-35 118.9 10.1 6.8e-18 64.2 0.6 2.3 2 0 0 2 2 2 2 PQ loop repeat MARVEL PF01284.23 KXL43034.1 - 0.038 14.0 4.2 0.68 10.0 0.0 3.0 3 0 0 3 3 3 0 Membrane-associating domain MtN3_slv PF03083.16 KXL43034.1 - 0.041 13.9 0.1 0.36 10.9 0.1 2.2 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange YrhC PF14143.6 KXL43034.1 - 0.12 12.5 0.1 0.55 10.4 0.1 2.2 2 0 0 2 2 2 0 YrhC-like protein Porin_3 PF01459.22 KXL43035.1 - 4.6e-43 147.6 0.0 5.2e-43 147.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin 6PF2K PF01591.18 KXL43036.1 - 2.2e-65 220.1 0.1 3e-65 219.7 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KXL43036.1 - 5.7e-22 78.3 0.6 6.5e-21 74.9 0.6 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KXL43036.1 - 0.017 15.3 0.0 0.048 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KXL43036.1 - 0.14 12.0 0.0 8.4 6.3 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF4112 PF13430.6 KXL43037.1 - 8.8e-32 109.5 0.2 1.1e-31 109.2 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Lung_7-TM_R PF06814.13 KXL43038.1 - 1.3e-63 215.0 10.3 1.6e-63 214.7 10.3 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor Strabismus PF06638.11 KXL43038.1 - 1.5 7.4 3.4 2.3 6.8 3.4 1.2 1 0 0 1 1 1 0 Strabismus protein AgrB PF04647.15 KXL43038.1 - 1.5 8.1 6.8 0.21 10.9 2.4 1.7 2 0 0 2 2 2 0 Accessory gene regulator B Frag1 PF10277.9 KXL43038.1 - 2.3 7.7 17.4 0.11 12.0 8.9 2.3 1 1 0 2 2 2 0 Frag1/DRAM/Sfk1 family EF-hand_7 PF13499.6 KXL43039.1 - 0.00061 20.2 0.0 1.2 9.6 0.0 2.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KXL43039.1 - 0.0011 18.7 0.0 1.1 9.4 0.0 3.7 4 0 0 4 4 4 1 EF-hand domain RPT PF13446.6 KXL43039.1 - 0.067 13.1 0.2 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 A repeated domain in UCH-protein EF-hand_8 PF13833.6 KXL43039.1 - 0.068 13.0 0.0 5.4 6.9 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain pair Porin_3 PF01459.22 KXL43040.1 - 1.4e-32 113.3 0.0 1.6e-32 113.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin COX2 PF00116.20 KXL43041.1 - 2.1e-39 134.1 0.4 9.2e-38 128.8 0.4 2.1 1 1 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain COX2_TM PF02790.15 KXL43041.1 - 0.00026 21.0 5.8 0.018 15.1 1.1 2.3 1 1 1 2 2 2 2 Cytochrome C oxidase subunit II, transmembrane domain GIY-YIG PF01541.24 KXL43043.1 - 2.2e-07 31.1 0.8 7.4e-07 29.4 0.8 2.0 1 0 0 1 1 1 1 GIY-YIG catalytic domain NUMOD3 PF07460.11 KXL43043.1 - 9.4e-07 29.0 6.6 1.5e-05 25.1 0.7 3.7 3 1 0 3 3 3 1 NUMOD3 motif (2 copies) NUMOD1 PF07453.13 KXL43043.1 - 4.8e-06 26.7 1.6 2.9e-05 24.2 0.5 2.7 2 0 0 2 2 2 1 NUMOD1 domain LAMTOR PF15454.6 KXL43045.1 - 3.3e-09 37.2 0.8 5.3e-09 36.6 0.5 1.7 2 0 0 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator ANTH PF07651.16 KXL43046.1 - 0.019 14.0 0.3 0.024 13.6 0.3 1.1 1 0 0 1 1 1 0 ANTH domain DUF3958 PF13125.6 KXL43046.1 - 0.22 11.8 5.3 14 5.9 5.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3958) DUF1849 PF08904.11 KXL43046.1 - 1 8.9 6.4 0.53 9.8 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1849) F-box PF00646.33 KXL43048.1 - 1.8e-06 27.7 6.3 1.8e-06 27.7 6.3 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KXL43048.1 - 1.2e-05 25.1 2.7 1.2e-05 25.1 2.7 2.4 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KXL43048.1 - 0.001 18.9 3.4 0.0029 17.5 0.7 2.2 2 0 0 2 2 2 1 F-box RPEL PF02755.15 KXL43048.1 - 0.034 13.8 0.5 0.093 12.5 0.5 1.8 1 0 0 1 1 1 0 RPEL repeat Smr PF01713.21 KXL43048.1 - 0.04 14.3 0.0 0.055 13.8 0.0 1.3 1 0 0 1 1 1 0 Smr domain HSP70 PF00012.20 KXL43049.1 - 1.5e-262 872.2 14.9 1.7e-262 872.0 14.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXL43049.1 - 7.7e-21 74.2 1.2 5.7e-20 71.4 0.5 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KXL43049.1 - 0.054 13.2 0.0 1.9 8.1 0.0 2.5 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 KXL43049.1 - 0.67 10.4 10.8 27 5.3 1.1 3.8 3 2 0 3 3 3 0 Cell division protein FtsA FIVAR PF07554.13 KXL43049.1 - 4.5 8.1 8.7 5.5 7.8 2.2 3.4 3 1 0 3 3 3 0 FIVAR domain F-actin_cap_A PF01267.17 KXL43052.1 - 3.5e-94 315.1 0.1 4e-94 315.0 0.1 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit CdiI_2 PF18593.1 KXL43052.1 - 0.01 16.4 0.2 0.8 10.4 0.0 2.4 2 0 0 2 2 2 0 CdiI immunity protein adh_short_C2 PF13561.6 KXL43053.1 - 2.9e-63 213.5 1.4 3.8e-63 213.2 1.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL43053.1 - 1.2e-54 184.8 1.8 1.6e-54 184.3 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL43053.1 - 1.2e-11 44.9 0.9 1.7e-11 44.3 0.9 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL43053.1 - 8.4e-05 22.1 1.7 0.00039 20.0 1.7 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PfkB PF00294.24 KXL43053.1 - 0.015 14.7 0.3 0.022 14.1 0.3 1.3 1 0 0 1 1 1 0 pfkB family carbohydrate kinase Polysacc_synt_2 PF02719.15 KXL43053.1 - 0.053 12.6 0.1 0.083 12.0 0.1 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ThiF PF00899.21 KXL43053.1 - 0.12 11.7 0.1 0.27 10.6 0.1 1.5 1 0 0 1 1 1 0 ThiF family GDP_Man_Dehyd PF16363.5 KXL43053.1 - 0.33 10.3 1.4 1.8 7.9 0.2 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase SSP160 PF06933.11 KXL43054.1 - 0.022 13.0 3.4 0.03 12.5 3.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.12 KXL43054.1 - 0.14 10.2 6.3 0.18 9.7 6.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein ERF PF04404.12 KXL43054.1 - 0.62 9.9 4.3 0.95 9.3 4.3 1.3 1 0 0 1 1 1 0 ERF superfamily Menin PF05053.13 KXL43054.1 - 1.6 7.0 3.7 2.2 6.6 3.7 1.1 1 0 0 1 1 1 0 Menin MRAP PF15183.6 KXL43055.1 - 0.15 12.0 0.3 0.23 11.4 0.3 1.3 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family adh_short_C2 PF13561.6 KXL43056.1 - 8.5e-50 169.5 1.5 1e-49 169.2 1.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL43056.1 - 2.6e-37 128.2 1.1 3.3e-37 127.8 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL43056.1 - 1.7e-15 57.4 0.6 2.3e-15 57.0 0.6 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL43056.1 - 0.00019 21.0 0.1 0.00036 20.1 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXL43056.1 - 0.0028 17.1 0.0 0.0042 16.5 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase FAD_binding_3 PF01494.19 KXL43056.1 - 0.023 14.0 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Polysacc_synt_2 PF02719.15 KXL43056.1 - 0.057 12.5 0.0 0.08 12.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HECT PF00632.25 KXL43057.1 - 4.8e-60 203.6 0.0 1e-59 202.5 0.0 1.5 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 KXL43057.1 - 3e-13 49.8 0.1 6e-13 48.8 0.1 1.5 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A DEAD PF00270.29 KXL43058.1 - 6.2e-43 146.6 0.0 1.1e-42 145.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXL43058.1 - 2.3e-29 102.0 0.1 1.6e-27 96.0 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL43058.1 - 0.00028 20.9 0.0 0.00049 20.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 KXL43058.1 - 0.016 15.0 0.4 6.7 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KXL43058.1 - 0.024 14.9 0.2 0.097 13.0 0.2 2.1 1 1 0 1 1 1 0 AAA domain UPF0524 PF15823.5 KXL43058.1 - 0.13 11.6 0.0 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 UPF0524 of C3orf70 MAPEG PF01124.18 KXL43059.1 - 2.8e-11 43.4 2.5 3.3e-11 43.2 2.5 1.0 1 0 0 1 1 1 1 MAPEG family FMN_dh PF01070.18 KXL43064.1 - 2.8e-109 365.3 0.0 3.2e-109 365.1 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KXL43064.1 - 0.0033 16.6 0.1 0.0052 16.0 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KXL43064.1 - 0.0039 16.2 1.3 0.007 15.4 1.3 1.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KXL43064.1 - 0.0049 16.2 0.2 2.1 7.6 0.2 2.2 1 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG SH3_12 PF18129.1 KXL43064.1 - 0.14 12.3 0.1 0.35 11.0 0.1 1.7 1 0 0 1 1 1 0 Xrn1 SH3-like domain MFS_1 PF07690.16 KXL43065.1 - 1.9e-39 135.6 27.8 1.9e-39 135.6 27.8 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_5 PF05631.14 KXL43065.1 - 6.8e-05 21.9 3.0 0.00016 20.7 1.8 1.9 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM Syntaxin-18_N PF10496.9 KXL43066.1 - 6e-07 29.6 0.9 3.5e-05 24.0 0.1 3.4 2 1 1 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 KXL43066.1 - 0.016 15.2 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 SNARE domain SAM_KSR1 PF13543.6 KXL43066.1 - 0.26 11.5 4.5 0.13 12.4 0.8 2.2 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 Sec20 PF03908.13 KXL43066.1 - 1.3 9.0 4.3 2.7 8.0 0.5 3.1 3 0 0 3 3 3 0 Sec20 KELK PF15796.5 KXL43066.1 - 8.9 6.9 8.8 2.6 8.5 0.4 3.5 3 1 1 4 4 4 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase FAD_binding_3 PF01494.19 KXL43067.1 - 0.00057 19.2 0.0 0.00059 19.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Arylsulfotran_2 PF14269.6 KXL43068.1 - 6.9e-44 150.4 0.1 2.2e-39 135.6 0.1 2.2 2 0 0 2 2 2 2 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXL43068.1 - 6.6e-14 51.6 0.3 1.1e-13 50.9 0.3 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) adh_short PF00106.25 KXL43069.1 - 9.1e-05 22.0 0.1 0.00015 21.3 0.1 1.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL43069.1 - 0.0017 18.0 0.0 0.0019 17.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase F420_oxidored PF03807.17 KXL43069.1 - 0.054 14.1 0.1 0.077 13.6 0.1 1.3 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DDE_1 PF03184.19 KXL43070.1 - 0.00012 21.8 0.2 0.00013 21.6 0.2 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Med31 PF05669.12 KXL43072.1 - 6.9e-26 90.1 0.0 8.7e-26 89.8 0.0 1.1 1 0 0 1 1 1 1 SOH1 Alpha_GJ PF03229.13 KXL43072.1 - 4.1 8.0 9.4 5.8 7.5 9.4 1.2 1 0 0 1 1 1 0 Alphavirus glycoprotein J DUF2933 PF11666.8 KXL43073.1 - 5.7 7.1 8.9 1.7 8.7 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2933) MARVEL PF01284.23 KXL43074.1 - 1.8e-23 83.2 13.4 2.1e-23 82.9 13.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain stn_TNFRSF12A PF12191.8 KXL43075.1 - 0.009 16.2 0.1 0.024 14.9 0.1 1.7 1 0 0 1 1 1 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain FXR_C1 PF16096.5 KXL43076.1 - 1.9 8.7 6.7 5.3 7.3 6.7 1.7 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 RhlB PF12300.8 KXL43076.1 - 5 7.2 25.0 0.06 13.5 17.0 1.8 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB NmrA PF05368.13 KXL43077.1 - 4.9e-14 52.5 0.0 6.1e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXL43077.1 - 9.1e-10 38.7 0.0 1.3e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Arrestin_C PF02752.22 KXL43078.1 - 0.0023 18.4 0.0 0.007 16.8 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KXL43078.1 - 0.034 14.2 0.1 0.88 9.6 0.0 2.8 3 0 0 3 3 3 0 Arrestin (or S-antigen), N-terminal domain PGA_cap PF09587.10 KXL43079.1 - 2.6e-65 220.4 0.3 3.6e-65 220.0 0.3 1.2 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap Ras PF00071.22 KXL43080.1 - 2.8e-58 196.1 0.0 3.3e-58 195.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXL43080.1 - 4.6e-35 120.4 0.0 7.8e-35 119.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXL43080.1 - 8.4e-15 54.7 0.0 1.6e-14 53.7 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KXL43080.1 - 3.2e-07 29.9 0.0 4e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KXL43080.1 - 3.7e-07 29.9 0.0 6.3e-07 29.1 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KXL43080.1 - 8.9e-05 22.5 0.0 0.00015 21.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KXL43080.1 - 0.00097 19.6 0.0 0.0021 18.5 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KXL43080.1 - 0.0091 15.9 0.1 2.6 7.9 0.0 2.7 2 1 0 2 2 2 2 RsgA GTPase TPP_enzyme_N PF02776.18 KXL43081.1 - 2.7e-32 111.7 0.0 1.7e-31 109.1 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXL43081.1 - 2e-19 69.7 0.0 5.3e-19 68.3 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KXL43081.1 - 1.4e-13 50.9 0.1 3.9e-13 49.5 0.1 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain VCPO_N PF17897.1 KXL43081.1 - 0.15 11.8 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Vanadium chloroperoxidase N-terminal domain UPF0261 PF06792.11 KXL43082.1 - 3.3e-161 536.7 0.1 3.8e-161 536.6 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) PEP_hydrolase PF09370.10 KXL43083.1 - 7.7e-138 458.1 0.5 8.7e-138 457.9 0.5 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like NMO PF03060.15 KXL43083.1 - 0.0038 16.7 0.1 0.0061 16.0 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Phage_holin_3_6 PF07332.11 KXL43085.1 - 0.0045 17.0 1.5 0.006 16.6 1.5 1.1 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III YfhO PF09586.10 KXL43085.1 - 0.043 12.1 0.3 0.053 11.7 0.3 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Mem_trans PF03547.18 KXL43085.1 - 0.056 11.8 2.2 0.069 11.5 2.2 1.0 1 0 0 1 1 1 0 Membrane transport protein Glyco_hydro_2_N PF02837.18 KXL43086.1 - 1.7e-14 54.1 0.0 4.1e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 KXL43086.1 - 4.5e-10 39.1 0.0 2.3e-09 36.8 0.0 2.0 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 KXL43086.1 - 1.7e-09 38.3 0.0 8.1e-09 36.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Thioredoxin PF00085.20 KXL43087.1 - 9e-24 83.4 0.0 1.2e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KXL43087.1 - 3e-05 24.4 0.0 6.3e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KXL43087.1 - 0.00014 21.3 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KXL43087.1 - 0.00067 19.8 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 KXL43087.1 - 0.0011 19.2 0.0 0.024 14.9 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KXL43087.1 - 0.0036 17.1 0.0 0.0049 16.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KXL43087.1 - 0.012 15.5 0.1 0.043 13.7 0.1 1.8 1 1 1 2 2 2 0 AhpC/TSA family Aa_trans PF01490.18 KXL43088.1 - 5.4e-77 259.2 28.2 6.3e-77 259.0 28.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Glyco_hydro_20 PF00728.22 KXL43089.1 - 9e-26 91.1 0.0 4.3e-25 88.9 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 KXL43089.1 - 5.2e-08 33.7 0.0 8.5e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 MFS_1 PF07690.16 KXL43090.1 - 1.2e-25 90.2 25.3 2.2e-24 86.1 25.3 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KXL43090.1 - 0.034 14.0 0.1 0.25 11.1 0.0 2.4 1 1 2 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) ApbA PF02558.16 KXL43091.1 - 4.4e-25 88.1 0.0 6.1e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KXL43091.1 - 1.2e-24 86.9 0.0 2.7e-24 85.7 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal GFO_IDH_MocA PF01408.22 KXL43091.1 - 0.029 15.2 0.0 0.088 13.6 0.0 1.9 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold ThiF PF00899.21 KXL43091.1 - 0.15 11.4 0.6 0.27 10.6 0.6 1.3 1 0 0 1 1 1 0 ThiF family Metallophos PF00149.28 KXL43092.1 - 4.6e-27 95.9 1.4 9.4e-27 94.8 1.4 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 KXL43092.1 - 3e-14 53.3 0.6 2.4e-13 50.5 0.9 2.4 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 KXL43092.1 - 2.2e-11 44.5 0.2 2.2e-11 44.5 0.2 2.3 3 0 0 3 3 3 1 Iron/zinc purple acid phosphatase-like protein C PhoD_N PF16655.5 KXL43092.1 - 0.0021 18.5 0.1 0.0047 17.4 0.1 1.6 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain NAD_binding_8 PF13450.6 KXL43093.1 - 6.2e-11 42.4 0.1 1.5e-10 41.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXL43093.1 - 0.00025 20.4 0.1 0.00044 19.6 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KXL43093.1 - 0.00037 21.0 0.8 0.00065 20.2 0.3 1.6 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXL43093.1 - 0.00062 19.1 0.2 0.0011 18.2 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXL43093.1 - 0.0018 17.1 0.1 0.0026 16.5 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KXL43093.1 - 0.0078 15.3 0.1 0.013 14.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXL43093.1 - 0.01 15.5 0.1 0.023 14.3 0.1 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KXL43093.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KXL43093.1 - 0.011 14.6 0.4 0.024 13.5 0.2 1.6 2 0 0 2 2 2 0 Tryptophan halogenase Amino_oxidase PF01593.24 KXL43093.1 - 0.012 15.0 0.0 0.027 13.8 0.0 1.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KXL43093.1 - 0.05 13.6 0.1 0.09 12.8 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding IlvN PF07991.12 KXL43093.1 - 0.23 11.0 0.5 14 5.3 0.1 2.8 3 1 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain HAD_2 PF13419.6 KXL43094.1 - 1.1e-23 84.2 0.0 1.6e-23 83.7 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXL43094.1 - 4.3e-11 43.5 0.0 1.1e-10 42.1 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXL43094.1 - 0.00026 21.0 0.0 0.00059 19.8 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KXL43094.1 - 0.00051 20.5 0.0 0.00074 20.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KXL43094.1 - 0.12 12.5 0.0 1.6 8.9 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Cyclin_N PF00134.23 KXL43096.1 - 3.3e-14 52.7 0.0 4.8e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KXL43096.1 - 2.2e-08 34.6 0.0 2.7e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Cyclin IBN_N PF03810.19 KXL43097.1 - 5.6e-14 51.8 0.0 2.3e-13 49.9 0.0 2.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KXL43097.1 - 0.00037 20.6 0.1 0.00037 20.6 0.1 2.5 4 0 0 4 4 4 1 Exportin 1-like protein Sigma_1s PF02454.16 KXL43097.1 - 0.036 14.0 0.3 0.12 12.3 0.3 1.9 1 0 0 1 1 1 0 Sigma 1s protein DUF3385 PF11865.8 KXL43097.1 - 0.048 13.6 0.1 0.13 12.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) ADH_N PF08240.12 KXL43099.1 - 2e-22 79.1 4.5 3.2e-22 78.5 4.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXL43099.1 - 1.7e-19 70.1 0.0 2.6e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXL43099.1 - 2.1e-11 45.0 0.0 3.8e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXL43099.1 - 0.00025 20.4 0.0 0.00038 19.8 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KXL43099.1 - 0.006 16.0 0.1 0.01 15.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Alk_phosphatase PF00245.20 KXL43100.1 - 1.8e-102 343.4 0.1 2.4e-102 343.0 0.1 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 KXL43100.1 - 1.7e-05 24.3 0.1 3e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily GRA6 PF05084.13 KXL43100.1 - 0.065 13.2 1.1 0.15 12.0 0.1 1.9 2 0 0 2 2 2 0 Granule antigen protein (GRA6) Rick_17kDa_Anti PF05433.15 KXL43101.1 - 9.8e-06 25.3 10.1 9.8e-06 25.3 10.1 2.3 2 0 0 2 2 2 1 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.6 KXL43101.1 - 1.1e-05 25.0 11.0 0.00056 19.6 10.2 2.2 2 0 0 2 2 2 1 YMGG-like Gly-zipper CbtA PF09490.10 KXL43101.1 - 0.1 12.3 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) TraT PF05818.12 KXL43101.1 - 0.15 11.7 2.1 0.27 10.9 2.1 1.4 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Gly-zipper_Omp PF13488.6 KXL43101.1 - 1.1 9.3 19.8 0.044 13.8 10.7 2.6 2 1 1 3 3 3 0 Glycine zipper Transgly_assoc PF04226.13 KXL43101.1 - 8.6 6.7 9.0 51 4.2 9.1 1.9 1 1 1 2 2 2 0 Transglycosylase associated protein Acyl-CoA_dh_1 PF00441.24 KXL43102.1 - 1.7e-33 115.9 0.2 3.4e-33 115.0 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 KXL43102.1 - 1.3e-18 66.9 0.1 3.7e-18 65.4 0.1 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 KXL43102.1 - 3.4e-18 65.6 0.3 6.6e-18 64.7 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KXL43102.1 - 7.1e-09 36.3 0.2 2.2e-08 34.7 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXL43102.1 - 6.6e-06 26.4 0.0 1.7e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain VARLMGL PF14383.6 KXL43103.1 - 0.063 12.8 0.1 0.16 11.5 0.1 1.8 1 0 0 1 1 1 0 DUF761-associated sequence motif Glyco_hydro_76 PF03663.14 KXL43104.1 - 4.5e-25 88.9 4.5 4e-17 62.8 0.2 3.4 2 2 0 2 2 2 2 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KXL43104.1 - 0.013 14.5 0.1 0.031 13.4 0.1 1.6 1 1 0 1 1 1 0 Glycosyl Hydrolase Family 88 ABC_membrane PF00664.23 KXL43105.1 - 4.7e-35 121.6 10.5 9.4e-35 120.6 10.5 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KXL43105.1 - 2.1e-32 112.5 0.3 9.9e-32 110.3 0.0 2.3 2 1 0 2 2 2 1 ABC transporter SMC_N PF02463.19 KXL43105.1 - 1.4e-06 27.9 0.2 1.6e-05 24.5 0.2 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KXL43105.1 - 0.013 15.7 0.4 0.39 11.0 0.4 3.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 KXL43105.1 - 0.039 13.8 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KXL43105.1 - 0.041 13.6 0.2 0.1 12.3 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KXL43105.1 - 0.073 13.3 0.2 0.87 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Cation_efflux PF01545.21 KXL43105.1 - 0.078 12.7 7.1 0.1 12.3 0.9 2.6 2 0 0 2 2 2 0 Cation efflux family Roughex PF06020.11 KXL43105.1 - 0.85 8.6 6.4 1.5 7.8 6.4 1.3 1 0 0 1 1 1 0 Drosophila roughex protein 5TM-5TMR_LYT PF07694.12 KXL43105.1 - 3.1 7.3 9.1 0.44 10.0 3.0 2.6 2 0 0 2 2 2 0 5TMR of 5TMR-LYT ADH_N PF08240.12 KXL43106.1 - 1.2e-29 102.4 2.9 3.8e-29 100.8 2.4 2.0 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXL43106.1 - 3e-24 85.5 0.1 5.7e-24 84.5 0.1 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXL43106.1 - 1.3e-08 34.6 0.0 1.9e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KXL43106.1 - 1e-05 26.6 0.0 1.6e-05 25.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 KXL43106.1 - 0.0016 18.7 0.1 0.0031 17.7 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain ADH_N_assoc PF13823.6 KXL43106.1 - 0.0047 16.8 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Pyr_redox PF00070.27 KXL43106.1 - 0.013 16.1 0.1 0.038 14.5 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXL43106.1 - 0.095 11.9 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NTP_transf_3 PF12804.7 KXL43106.1 - 0.12 12.7 0.0 0.25 11.7 0.0 1.5 1 1 0 1 1 1 0 MobA-like NTP transferase domain AlaDh_PNT_C PF01262.21 KXL43106.1 - 0.14 11.5 0.1 0.23 10.7 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KXL43106.1 - 0.15 12.5 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ADH_N PF08240.12 KXL43107.1 - 1.3e-23 83.0 5.9 2.3e-23 82.2 5.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXL43107.1 - 3.6e-12 46.4 0.0 4.9e-11 42.7 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXL43107.1 - 0.0011 18.3 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KXL43107.1 - 0.014 14.8 0.0 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 KXL43107.1 - 0.037 14.4 0.1 0.85 10.0 0.0 2.6 3 0 0 3 3 3 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_N PF08240.12 KXL43108.1 - 1.2e-26 92.7 0.6 2e-26 92.0 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXL43108.1 - 4.4e-22 78.4 1.7 6.7e-22 77.9 1.7 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXL43108.1 - 1.6e-06 29.2 0.7 2.8e-06 28.4 0.7 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KXL43108.1 - 0.038 13.9 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase ACT_3 PF10000.9 KXL43109.1 - 1.6e-10 40.8 0.0 2.1e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 ACT domain ACT_7 PF13840.6 KXL43109.1 - 1.7e-06 27.7 0.1 3.4e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 ACT domain GATA PF00320.27 KXL43110.1 - 0.00022 20.8 0.8 0.00049 19.6 0.8 1.6 1 0 0 1 1 1 1 GATA zinc finger Zn-ribbon_8 PF09723.10 KXL43110.1 - 0.011 15.8 0.8 0.027 14.6 0.8 1.7 1 0 0 1 1 1 0 Zinc ribbon domain LRR_4 PF12799.7 KXL43110.1 - 0.011 16.1 5.9 2.4 8.7 0.0 5.2 4 3 2 6 6 6 0 Leucine Rich repeats (2 copies) TFIIF_alpha PF05793.12 KXL43110.1 - 0.064 11.8 21.1 0.09 11.4 21.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TF_Zn_Ribbon PF08271.12 KXL43110.1 - 0.065 12.8 0.2 0.16 11.5 0.2 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding LRR_1 PF00560.33 KXL43110.1 - 0.075 13.6 2.9 27 5.9 0.1 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat CDC45 PF02724.14 KXL43110.1 - 0.39 9.0 13.2 0.53 8.5 13.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KXL43110.1 - 0.53 8.4 20.5 0.78 7.9 20.5 1.1 1 0 0 1 1 1 0 Nop14-like family Consortin_C PF15281.6 KXL43110.1 - 1.5 8.9 3.5 5 7.1 3.5 1.8 1 0 0 1 1 1 0 Consortin C-terminus RR_TM4-6 PF06459.12 KXL43110.1 - 4.1 7.2 13.5 6.9 6.4 13.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HSP70 PF00012.20 KXL43111.1 - 1.1e-13 50.3 0.0 3.1e-12 45.5 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein FtsA PF14450.6 KXL43111.1 - 0.0066 16.9 0.5 0.12 12.8 0.0 2.5 2 0 0 2 2 2 1 Cell division protein FtsA Leu_zip PF15294.6 KXL43112.1 - 0.4 10.1 8.5 1.2 8.5 8.5 1.7 1 1 0 1 1 1 0 Leucine zipper ABC_tran_CTD PF16326.5 KXL43112.1 - 6.9 7.0 8.4 0.27 11.5 1.3 2.3 3 0 0 3 3 3 0 ABC transporter C-terminal domain BING4CT PF08149.11 KXL43113.1 - 1.5e-40 136.9 0.0 2.2e-36 123.5 0.0 3.2 3 0 0 3 3 3 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 KXL43113.1 - 2.9e-09 37.1 0.1 6.1 7.2 0.0 6.1 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXL43113.1 - 1.4e-05 25.7 0.8 0.22 12.5 0.0 4.8 5 1 0 5 5 5 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 KXL43113.1 - 0.0053 15.9 0.0 0.02 13.9 0.0 1.9 2 0 0 2 2 2 1 Coatomer WD associated region DUF1974 PF09317.11 KXL43113.1 - 0.21 11.1 1.3 0.33 10.5 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) Aminotran_1_2 PF00155.21 KXL43114.1 - 8.4e-89 298.3 0.0 9.9e-89 298.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Hpt PF01627.23 KXL43117.1 - 9.1e-12 45.1 0.1 1.4e-11 44.5 0.1 1.4 1 0 0 1 1 1 1 Hpt domain Ribosomal_L3 PF00297.22 KXL43119.1 - 1.2e-186 620.1 9.7 1.4e-186 619.9 9.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 SecY PF00344.20 KXL43120.1 - 2.7e-71 240.3 8.8 3.5e-71 240.0 8.8 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KXL43120.1 - 2e-17 62.7 0.2 5.4e-17 61.3 0.2 1.8 1 0 0 1 1 1 1 Plug domain of Sec61p DUF3464 PF11947.8 KXL43121.1 - 0.01 15.6 0.1 0.017 14.9 0.1 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF4131 PF13567.6 KXL43121.1 - 1.5 8.4 5.5 22 4.6 3.3 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4131) PIG-Y PF15159.6 KXL43121.1 - 6.9 7.7 9.4 38 5.3 0.1 2.5 1 1 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Tetraspanin PF00335.20 KXL43122.1 - 2.6e-08 33.8 0.1 4.6e-08 33.0 0.1 1.5 1 1 0 1 1 1 1 Tetraspanin family DUF1462 PF07315.11 KXL43122.1 - 0.13 12.6 0.1 0.82 10.0 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1462) Mus7 PF09462.10 KXL43123.1 - 2.8e-136 455.9 3.3 5.7e-136 454.9 3.3 1.5 1 0 0 1 1 1 1 Mus7/MMS22 family Apolipoprotein PF01442.18 KXL43123.1 - 0.23 11.3 3.2 0.22 11.4 0.2 2.4 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain SNAP PF14938.6 KXL43124.1 - 8e-116 386.4 19.3 9e-116 386.2 19.3 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 KXL43124.1 - 6.9e-05 22.6 11.4 2.7 8.2 0.0 5.7 3 1 2 5 5 5 3 Tetratricopeptide repeat Spatacsin_C PF14649.6 KXL43124.1 - 0.0021 17.2 8.9 0.11 11.5 0.1 3.0 1 1 2 3 3 3 2 Spatacsin C-terminus TPR_12 PF13424.6 KXL43124.1 - 0.0023 18.2 18.0 0.0057 16.9 3.1 4.2 2 1 3 5 5 5 2 Tetratricopeptide repeat TRAPPC-Trs85 PF12739.7 KXL43124.1 - 0.013 14.5 9.2 0.03 13.3 4.6 2.2 1 1 1 2 2 2 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_2 PF07719.17 KXL43124.1 - 0.015 15.4 18.9 2.9 8.2 0.7 6.3 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXL43124.1 - 0.016 15.0 18.0 0.16 11.9 0.2 6.0 3 1 2 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXL43124.1 - 0.025 14.8 12.6 0.31 11.4 0.2 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat TOM20_plant PF06552.12 KXL43124.1 - 0.12 12.1 6.2 0.47 10.2 0.4 2.6 1 1 1 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 PhageMin_Tail PF10145.9 KXL43124.1 - 0.14 12.0 4.6 1.8 8.4 3.0 2.7 1 1 1 2 2 2 0 Phage-related minor tail protein TPR_6 PF13174.6 KXL43124.1 - 0.29 11.9 16.9 15 6.4 0.2 6.0 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF5375 PF17345.2 KXL43125.1 - 0.054 13.4 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5375) Glu-tRNAGln PF02686.15 KXL43126.1 - 3.9e-08 33.5 0.0 1.3e-07 31.8 0.0 1.8 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit DUF2996 PF11210.8 KXL43126.1 - 0.17 12.3 0.0 0.38 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2996) DUF1772 PF08592.11 KXL43127.1 - 3.1e-06 27.6 6.3 4.2e-06 27.1 6.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) RNA_pol_A_bac PF01000.26 KXL43129.1 - 1.5e-27 96.2 0.0 3e-27 95.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KXL43129.1 - 7.7e-15 54.1 0.0 1.1e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain An_peroxidase PF03098.15 KXL43130.1 - 1.4e-35 122.9 0.0 2.4e-25 89.1 0.0 3.6 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 KXL43130.1 - 5e-07 28.8 0.0 1.4e-06 27.4 0.0 1.6 2 0 0 2 2 2 1 Cytochrome P450 Glyco_hydro_2_N PF02837.18 KXL43131.1 - 2.5e-16 60.1 0.0 5.9e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 KXL43131.1 - 2.4e-11 43.3 0.0 1.7e-10 40.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 KXL43131.1 - 3e-09 37.5 0.0 6.6e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Steroid_dh PF02544.16 KXL43132.1 - 2.3e-33 115.3 0.1 3.3e-33 114.8 0.1 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KXL43132.1 - 0.0011 18.5 0.3 0.0015 18.1 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KXL43132.1 - 0.0053 17.1 0.3 0.013 15.9 0.3 1.7 1 1 0 1 1 1 1 Phospholipid methyltransferase HMG_box PF00505.19 KXL43134.1 - 3e-22 78.8 0.6 6e-22 77.8 0.6 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXL43134.1 - 6.2e-07 29.9 0.4 1.5e-06 28.7 0.4 1.6 1 0 0 1 1 1 1 HMG-box domain Pyridoxal_deC PF00282.19 KXL43136.1 - 3.2e-19 68.9 0.0 4.6e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KXL43136.1 - 2.6e-05 23.4 0.0 8.3e-05 21.7 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KXL43136.1 - 0.015 14.7 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF1775 PF07987.11 KXL43136.1 - 0.03 14.6 0.0 0.055 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unkown function (DUF1775) DUF3802 PF12290.8 KXL43136.1 - 0.089 13.3 0.0 1.6 9.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3802) COX6B PF02297.17 KXL43137.1 - 4.5e-20 71.7 5.5 5.3e-20 71.4 5.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 KXL43137.1 - 0.011 15.7 1.5 0.011 15.7 1.5 1.5 1 1 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, APOBEC_C PF05240.14 KXL43137.1 - 0.014 15.3 1.0 0.017 15.0 0.8 1.4 1 1 0 1 1 1 0 APOBEC-like C-terminal domain B12D PF06522.11 KXL43138.1 - 0.013 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit ApoO PF09769.9 KXL43138.1 - 0.095 12.7 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein O Arginase PF00491.21 KXL43139.1 - 4e-91 305.4 0.0 5e-91 305.1 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KXL43139.1 - 0.07 13.3 0.0 0.11 12.7 0.0 1.4 1 1 0 1 1 1 0 UPF0489 domain MatE PF01554.18 KXL43140.1 - 1.3e-57 193.9 22.4 2.3e-29 102.1 6.5 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KXL43140.1 - 1.7e-08 34.6 7.1 1.7e-08 34.6 7.1 4.0 3 2 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain DUF378 PF04070.12 KXL43140.1 - 0.029 14.2 3.3 0.031 14.2 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF378) CD225 PF04505.12 KXL43140.1 - 0.25 11.5 4.3 0.09 12.9 0.7 2.2 2 0 0 2 2 2 0 Interferon-induced transmembrane protein AA_permease_2 PF13520.6 KXL43141.1 - 4.4e-44 151.0 52.0 5.1e-44 150.8 52.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXL43141.1 - 1.8e-15 56.5 40.9 3e-15 55.8 40.9 1.2 1 0 0 1 1 1 1 Amino acid permease MS_channel PF00924.18 KXL43141.1 - 0.053 13.1 0.1 0.14 11.7 0.1 1.7 1 0 0 1 1 1 0 Mechanosensitive ion channel NAGLU PF05089.12 KXL43142.1 - 1.5e-131 438.3 11.3 2.4e-131 437.7 11.3 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 KXL43142.1 - 3.9e-65 220.0 4.1 6.2e-65 219.4 4.1 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 KXL43142.1 - 3.6e-21 74.7 0.0 9.2e-21 73.4 0.0 1.7 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Mito_carr PF00153.27 KXL43143.1 - 2e-59 197.5 0.2 1.1e-20 73.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXL43143.1 - 0.038 13.2 0.3 0.14 11.2 0.1 1.9 2 0 0 2 2 2 0 Gammaproteobacterial serine protease tRNA-synt_2d PF01409.20 KXL43144.1 - 1.4e-44 152.4 0.9 9.2e-24 84.3 0.0 2.4 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KXL43144.1 - 5.9e-25 87.5 0.0 1.4e-24 86.3 0.0 1.7 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Reprolysin_5 PF13688.6 KXL43145.1 - 2.2e-55 187.9 13.6 2.2e-55 187.9 13.6 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KXL43145.1 - 2.3e-45 154.7 9.1 4.4e-45 153.8 9.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KXL43145.1 - 5.8e-43 147.1 6.3 5.8e-43 147.1 6.3 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 KXL43145.1 - 2.8e-18 66.5 29.9 2.8e-18 66.5 29.9 4.6 4 1 0 4 4 4 1 Disintegrin Reprolysin_3 PF13582.6 KXL43145.1 - 9.1e-08 32.7 0.3 3.5e-07 30.8 0.3 2.1 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DUF1485 PF07364.12 KXL43146.1 - 7.1e-102 340.6 0.0 9.5e-102 340.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M81 MlrC_C PF07171.12 KXL43146.1 - 3.2e-57 193.6 0.1 5.1e-57 192.9 0.1 1.3 1 0 0 1 1 1 1 MlrC C-terminus Sugar_tr PF00083.24 KXL43147.1 - 4.3e-67 226.9 16.9 5.2e-67 226.7 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL43147.1 - 2.9e-22 79.1 32.6 2.9e-22 79.1 32.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXL43147.1 - 0.00093 17.7 2.5 0.0018 16.8 2.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Arylsulfotran_2 PF14269.6 KXL43148.1 - 6.7e-55 186.6 0.9 9.3e-55 186.1 0.9 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXL43148.1 - 7.1e-17 61.4 3.2 5.5e-16 58.5 3.2 1.9 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) AMP-binding PF00501.28 KXL43149.1 - 1e-73 248.4 0.0 1.5e-73 247.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KXL43149.1 - 1.1e-61 208.3 0.0 2.3e-61 207.2 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.25 KXL43149.1 - 3.3e-51 173.5 0.4 7.7e-51 172.3 0.4 1.7 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL43149.1 - 6.8e-39 133.8 0.3 1.4e-38 132.8 0.3 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL43149.1 - 2.3e-19 70.0 0.4 1.9e-14 54.0 0.2 2.4 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 KXL43149.1 - 1.4e-17 64.0 0.1 1.8e-10 40.7 0.0 3.0 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KXL43149.1 - 2.2e-15 56.7 0.0 2.5e-14 53.4 0.0 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.6 KXL43149.1 - 2.5e-08 34.0 0.1 5.2e-06 26.5 0.1 3.4 3 0 0 3 3 3 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KXL43149.1 - 2.2e-06 27.0 0.4 0.00088 18.5 0.0 3.0 3 1 0 3 3 3 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KXL43149.1 - 3.6e-06 26.3 0.2 0.016 14.3 0.0 2.8 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KXL43149.1 - 7.4e-06 25.2 0.0 0.00094 18.3 0.0 3.0 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 KXL43149.1 - 1.6e-05 25.8 0.1 0.00017 22.5 0.1 2.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ApbA PF02558.16 KXL43149.1 - 0.0033 17.1 0.1 0.0086 15.7 0.1 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GDP_Man_Dehyd PF16363.5 KXL43149.1 - 0.0061 16.0 0.0 1.8 7.9 0.0 2.4 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Neugrin PF06413.11 KXL43150.1 - 1.3e-10 41.7 0.3 1.3e-10 41.7 0.3 1.5 2 0 0 2 2 2 1 Neugrin MRP-L20 PF12824.7 KXL43150.1 - 2e-07 31.3 3.7 4.1e-07 30.3 3.7 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_23 PF13384.6 KXL43150.1 - 0.01 15.6 0.7 0.18 11.7 0.2 2.7 2 1 0 2 2 2 0 Homeodomain-like domain AAA_28 PF13521.6 KXL43150.1 - 0.084 13.1 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain HTH_DeoR PF08220.12 KXL43150.1 - 0.17 11.6 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Rgp1 PF08737.10 KXL43151.1 - 7.7e-141 470.0 0.0 1.2e-140 469.4 0.0 1.3 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.29 KXL43151.1 - 0.00019 21.5 0.0 0.0056 16.7 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KXL43151.1 - 0.025 15.0 0.0 0.95 9.9 0.0 2.6 3 0 0 3 3 3 0 Arrestin (or S-antigen), C-terminal domain Metallophos PF00149.28 KXL43152.1 - 6.8e-10 39.8 0.2 9.7e-10 39.3 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXL43152.1 - 0.063 13.5 0.0 0.13 12.5 0.0 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Pectate_lyase_3 PF12708.7 KXL43154.1 - 6.9e-60 202.6 16.4 2.6e-53 181.1 7.9 3.4 3 0 0 3 3 3 2 Pectate lyase superfamily protein NosD PF05048.13 KXL43154.1 - 0.00012 21.4 8.7 0.00012 21.4 8.7 2.3 2 1 1 3 3 3 1 Periplasmic copper-binding protein (NosD) Opy2 PF09463.10 KXL43155.1 - 4.7e-11 42.8 19.4 7.3e-11 42.2 19.4 1.3 1 0 0 1 1 1 1 Opy2 protein MAP17 PF15807.5 KXL43155.1 - 0.038 14.2 0.1 0.073 13.3 0.1 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Polysacc_deac_1 PF01522.21 KXL43156.1 - 3.3e-22 78.7 0.0 4.7e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.13 KXL43156.1 - 0.0025 17.0 0.0 0.0059 15.8 0.0 1.6 2 0 0 2 2 2 1 Divergent polysaccharide deacetylase Ribonuc_2-5A PF06479.12 KXL43156.1 - 0.01 16.0 0.0 0.4 10.9 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease 2-5A HTH_39 PF14090.6 KXL43156.1 - 0.057 13.2 0.0 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain GGDEF_2 PF17853.1 KXL43156.1 - 0.067 13.5 0.0 0.16 12.3 0.0 1.6 2 0 0 2 2 2 0 GGDEF-like domain PipA PF07108.11 KXL43156.1 - 0.17 11.4 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 PipA protein Peptidase_M20 PF01546.28 KXL43157.1 - 1.2e-31 110.1 0.0 1.8e-31 109.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXL43157.1 - 5.7e-12 45.5 0.0 9.3e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Oxysterol_BP PF01237.18 KXL43158.1 - 9.7e-58 195.8 0.0 5.7e-55 186.7 0.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein TetR_C_20 PF17925.1 KXL43158.1 - 0.21 11.9 0.0 0.47 10.8 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Syja_N PF02383.18 KXL43159.1 - 3.7e-94 315.6 0.0 5.4e-94 315.1 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 KXL43159.1 - 3.4e-36 123.4 0.0 8e-36 122.2 0.0 1.7 1 0 0 1 1 1 1 Inositol phosphatase Acetyltransf_10 PF13673.7 KXL43160.1 - 7.5e-07 29.1 0.0 0.023 14.6 0.0 2.6 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXL43160.1 - 0.0021 18.3 0.0 0.005 17.1 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.6 KXL43160.1 - 0.0031 18.2 0.0 0.097 13.4 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXL43160.1 - 0.0048 17.3 0.0 0.011 16.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXL43160.1 - 0.014 15.5 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Asp PF00026.23 KXL43161.1 - 4.6e-71 239.8 12.7 5.3e-71 239.6 12.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXL43161.1 - 1.8e-06 28.3 3.8 0.00025 21.3 2.8 3.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KXL43161.1 - 0.00019 22.0 2.2 0.0051 17.4 0.8 2.9 2 1 0 2 2 2 1 Aspartyl protease Cloacin_immun PF03513.14 KXL43162.1 - 0.11 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Cloacin immunity protein Aminotran_1_2 PF00155.21 KXL43164.1 - 5e-09 35.8 0.0 6.3e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KXL43164.1 - 0.027 13.3 0.1 1.3 7.7 0.0 2.1 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase adh_short PF00106.25 KXL43165.1 - 6.3e-26 91.0 0.0 8.2e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL43165.1 - 1.2e-15 57.7 0.0 1.5e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 KXL43165.1 - 0.0013 17.9 0.0 0.0018 17.5 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KXL43165.1 - 0.0021 18.0 0.0 0.0033 17.3 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXL43165.1 - 0.063 13.2 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding 3HCDH_N PF02737.18 KXL43165.1 - 0.21 11.5 0.0 0.32 10.8 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3253 PF11625.8 KXL43166.1 - 1.2e-10 41.5 0.0 1.7e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3253) zf-CCHC PF00098.23 KXL43167.1 - 2.4e-12 46.3 36.0 1.7e-05 24.7 3.4 5.8 5 1 0 5 5 5 4 Zinc knuckle zf-CCHC_4 PF14392.6 KXL43167.1 - 0.01 15.6 27.4 0.56 10.0 0.2 5.4 4 1 1 5 5 5 4 Zinc knuckle LRIF1 PF15741.5 KXL43167.1 - 0.023 13.2 6.2 0.036 12.6 6.2 1.2 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 zf-CCHC_3 PF13917.6 KXL43167.1 - 0.8 9.7 16.6 1.4 8.9 0.1 4.4 3 1 1 4 4 4 0 Zinc knuckle ORMDL PF04061.14 KXL43168.1 - 1.5e-57 193.2 6.0 1.9e-57 192.9 6.0 1.1 1 0 0 1 1 1 1 ORMDL family NmrA PF05368.13 KXL43169.1 - 3.3e-20 72.7 0.0 4.2e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXL43169.1 - 7.8e-11 42.2 0.0 2e-10 40.9 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 KXL43169.1 - 0.02 15.0 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 KXL43169.1 - 0.067 13.6 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KXL43169.1 - 0.093 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KXL43169.1 - 0.099 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF3391 PF11871.8 KXL43170.1 - 0.11 13.0 2.9 0.15 12.6 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) YabA PF06156.13 KXL43170.1 - 0.61 10.7 9.3 4.9 7.9 9.3 2.0 1 1 0 1 1 1 0 Initiation control protein YabA KLRAQ PF10205.9 KXL43170.1 - 0.69 10.2 9.6 4.2 7.7 9.6 2.1 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein HAD_2 PF13419.6 KXL43171.1 - 1.6e-08 34.9 0.0 7.2e-07 29.5 0.0 2.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXL43171.1 - 3e-07 30.9 0.0 0.013 15.8 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXL43171.1 - 1.4e-06 28.2 0.1 8.6e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like BESS PF02944.20 KXL43171.1 - 0.022 14.6 0.0 0.054 13.3 0.0 1.6 2 0 0 2 2 2 0 BESS motif HAD PF12710.7 KXL43171.1 - 0.085 13.3 0.1 0.77 10.1 0.1 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase T3SS_ATPase_C PF18269.1 KXL43171.1 - 0.17 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 T3SS EscN ATPase C-terminal domain OPT PF03169.15 KXL43172.1 - 3.3e-145 485.2 47.6 3.7e-145 485.0 47.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Zip PF02535.22 KXL43173.1 - 5.8e-60 203.3 0.0 7.1e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter SR-25 PF10500.9 KXL43174.1 - 0.007 16.0 12.2 0.0086 15.7 12.2 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF515 PF04415.12 KXL43174.1 - 2.2 6.6 7.6 2.5 6.4 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Pap_E4 PF02711.14 KXL43174.1 - 8 7.5 8.0 1.1 10.3 3.6 1.7 1 1 1 2 2 2 0 E4 protein IMUP PF15761.5 KXL43174.1 - 8.3 7.1 14.2 1.5 9.5 10.1 1.7 1 1 0 2 2 2 0 Immortalisation up-regulated protein Abhydrolase_3 PF07859.13 KXL43175.1 - 1.2e-31 110.2 0.1 1.5e-31 109.9 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXL43175.1 - 0.00017 20.6 0.0 0.00021 20.3 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 KXL43175.1 - 0.00037 21.2 0.0 0.00053 20.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXL43175.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MFS_1 PF07690.16 KXL43176.1 - 3.1e-44 151.3 24.4 2.1e-42 145.3 22.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL43176.1 - 9.7e-14 51.1 3.7 9.7e-14 51.1 3.7 2.3 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KXL43176.1 - 3.4e-09 35.7 4.9 3.4e-09 35.7 4.9 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KXL43176.1 - 0.0039 16.1 2.9 0.0075 15.2 2.9 1.6 1 0 0 1 1 1 1 MFS_1 like family OATP PF03137.20 KXL43176.1 - 3 6.0 6.8 2.6 6.2 0.0 2.9 2 2 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family ANAPC4 PF12896.7 KXL43177.1 - 1.9e-48 164.7 0.5 3.2e-48 163.9 0.5 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 KXL43177.1 - 1.2e-18 67.2 0.0 6.1e-18 64.9 0.0 2.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain ABM PF03992.16 KXL43178.1 - 4.1e-06 26.8 0.0 7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Adap_comp_sub PF00928.21 KXL43179.1 - 2.5e-13 50.0 0.0 3.6e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KXL43179.1 - 0.00015 21.7 0.0 0.00023 21.1 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Mon1 PF03164.14 KXL43179.1 - 0.00086 18.5 0.0 0.0013 17.9 0.0 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 DUF2420 PF10336.9 KXL43180.1 - 8.5e-19 67.6 0.3 1.4e-18 66.9 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) PAM2 PF07145.15 KXL43181.1 - 0.0067 16.0 0.2 0.024 14.3 0.2 2.0 1 0 0 1 1 1 1 Ataxin-2 C-terminal region Glyco_hydro_16 PF00722.21 KXL43183.1 - 3e-10 39.8 0.1 6.6e-10 38.7 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 RskA PF10099.9 KXL43183.1 - 0.067 13.5 0.0 0.099 12.9 0.0 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA BppU_N PF10651.9 KXL43183.1 - 0.096 12.4 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 BppU N-terminal domain DUF485 PF04341.12 KXL43183.1 - 0.11 12.4 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF485 COX6C PF02937.15 KXL43183.1 - 0.25 11.5 0.4 0.67 10.1 0.4 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc DUF3772 PF12607.8 KXL43183.1 - 5.5 6.8 6.0 29 4.5 2.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) NDUF_B4 PF07225.12 KXL43184.1 - 0.0013 18.6 0.2 0.0015 18.4 0.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) GST_N PF02798.20 KXL43185.1 - 4.5e-08 33.3 0.0 7.9e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXL43185.1 - 1.2e-06 28.6 0.0 2.2e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXL43185.1 - 1.2e-05 25.7 0.0 2.1e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXL43185.1 - 0.00016 21.6 0.0 0.00065 19.7 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXL43185.1 - 0.001 19.3 0.0 0.0017 18.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXL43185.1 - 0.0061 16.8 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CagY_M PF07337.11 KXL43186.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 DC-EC Repeat SRA PF18491.1 KXL43187.1 - 0.13 12.4 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 SET and RING associated domain BTB_2 PF02214.22 KXL43188.1 - 5.4e-07 29.9 0.3 0.0014 19.0 0.0 2.7 3 0 0 3 3 3 2 BTB/POZ domain BTB PF00651.31 KXL43188.1 - 0.012 15.8 0.0 5.3 7.3 0.0 2.4 2 0 0 2 2 2 0 BTB/POZ domain Zn_clus PF00172.18 KXL43189.1 - 1.3e-08 34.8 6.6 2.5e-08 33.9 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.21 KXL43190.1 - 4.2e-99 332.5 0.0 5.6e-99 332.1 0.0 1.2 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.16 KXL43191.1 - 6.4e-21 74.7 54.7 6.4e-14 51.6 22.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GRIM-19 PF06212.12 KXL43191.1 - 0.21 11.5 0.0 3.4 7.6 0.0 2.4 2 0 0 2 2 2 0 GRIM-19 protein PDEase_II PF02112.15 KXL43192.1 - 4.3e-50 170.7 0.0 8.8e-23 80.9 0.0 3.1 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 KXL43192.1 - 0.00097 18.7 0.1 0.0022 17.6 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KXL43192.1 - 0.029 14.4 0.2 0.056 13.4 0.2 1.7 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Ribosomal_S21 PF01165.20 KXL43192.1 - 0.14 11.9 0.1 0.38 10.5 0.1 1.7 1 0 0 1 1 1 0 Ribosomal protein S21 PP2C PF00481.21 KXL43194.1 - 4e-37 128.3 0.0 1.2e-31 110.3 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KXL43194.1 - 1.9e-05 24.4 0.0 4.6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C DnaJ PF00226.31 KXL43196.1 - 3.5e-14 52.7 0.0 9.6e-14 51.3 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 KXL43196.1 - 4.7e-14 52.2 0.4 1.5e-08 34.2 0.1 2.6 3 0 0 3 3 3 2 Sec63 Brl domain DUF2157 PF09925.9 KXL43196.1 - 0.087 12.6 0.1 0.93 9.3 0.0 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) GAT PF03127.14 KXL43199.1 - 1.3e-17 63.8 0.7 2.1e-17 63.2 0.1 1.6 2 0 0 2 2 2 1 GAT domain ANAPC10 PF03256.16 KXL43200.1 - 1.2e-45 155.5 0.0 1.8e-45 154.9 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) DUF4637 PF15470.6 KXL43200.1 - 0.056 13.2 1.3 0.12 12.1 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) INCENP_ARK-bind PF03941.15 KXL43200.1 - 0.19 11.7 0.1 0.19 11.7 0.1 3.0 2 1 0 2 2 2 0 Inner centromere protein, ARK binding region AIM3 PF17096.5 KXL43200.1 - 0.34 11.9 1.2 0.38 11.7 0.1 1.7 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 Nop14 PF04147.12 KXL43200.1 - 2.4 6.3 9.7 3.6 5.7 9.7 1.2 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.10 KXL43200.1 - 8.9 6.8 20.0 9.5 6.7 15.3 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain His_Phos_1 PF00300.22 KXL43201.1 - 1.2e-11 44.7 2.2 7.1e-11 42.2 2.2 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Glyco_transf_28 PF03033.20 KXL43203.1 - 1.4e-18 67.3 0.1 1.5e-17 63.9 0.1 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KXL43203.1 - 1.1e-06 27.7 0.0 1.8e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KXL43203.1 - 0.00076 19.5 0.0 0.0018 18.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain MARVEL PF01284.23 KXL43204.1 - 5.2e-24 84.9 10.7 6.5e-24 84.6 10.7 1.0 1 0 0 1 1 1 1 Membrane-associating domain NADHdeh_related PF10125.9 KXL43204.1 - 0.092 12.1 1.5 0.12 11.7 1.5 1.2 1 0 0 1 1 1 0 NADH dehydrogenase I, subunit N related protein NDUF_B8 PF05821.11 KXL43205.1 - 0.014 15.3 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Methyltransf_31 PF13847.6 KXL43206.1 - 6.3e-28 97.5 0.0 8.6e-28 97.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL43206.1 - 7.2e-20 71.5 0.1 1.6e-19 70.4 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXL43206.1 - 1.1e-16 60.9 0.0 1.5e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KXL43206.1 - 1.2e-16 61.1 0.0 2.6e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXL43206.1 - 1.4e-11 44.6 0.0 1.9e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL43206.1 - 3.1e-11 43.9 0.0 5.2e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXL43206.1 - 7.1e-07 28.9 0.5 1.1e-06 28.3 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 KXL43206.1 - 2.4e-06 27.4 0.1 4.7e-06 26.5 0.1 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 KXL43206.1 - 1.3e-05 25.2 0.0 2.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXL43206.1 - 0.00011 21.6 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KXL43206.1 - 0.0004 20.0 0.0 0.0006 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 KXL43206.1 - 0.0013 18.1 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB FtsJ PF01728.19 KXL43206.1 - 0.0031 17.6 0.1 0.0052 16.9 0.1 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KXL43206.1 - 0.008 15.7 0.3 0.017 14.6 0.2 1.6 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_8 PF05148.15 KXL43206.1 - 0.021 14.7 1.0 0.1 12.4 1.0 1.9 1 1 0 1 1 1 0 Hypothetical methyltransferase UPF0020 PF01170.18 KXL43206.1 - 0.047 13.4 0.3 0.089 12.5 0.3 1.5 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 CheR PF01739.18 KXL43206.1 - 0.1 12.1 0.1 0.64 9.5 0.0 2.0 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_18 PF12847.7 KXL43206.1 - 0.16 11.9 0.1 0.29 11.0 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 KXL43206.1 - 0.19 10.6 0.0 0.31 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) ABC_membrane_2 PF06472.15 KXL43207.1 - 1.2e-87 293.7 0.3 3.4e-87 292.3 0.0 1.8 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KXL43207.1 - 1.5e-16 61.1 0.0 2.9e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter THOC7 PF05615.13 KXL43207.1 - 0.0029 17.9 0.7 0.0065 16.8 0.7 1.5 1 0 0 1 1 1 1 Tho complex subunit 7 AAA_23 PF13476.6 KXL43207.1 - 0.0047 17.5 1.4 0.27 11.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KXL43207.1 - 0.014 15.2 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Mg_chelatase PF01078.21 KXL43207.1 - 0.037 13.4 0.1 0.066 12.6 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 KXL43207.1 - 0.066 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 KXL43207.1 - 0.075 13.5 0.0 0.88 10.0 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXL43207.1 - 0.076 12.8 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXL43207.1 - 0.13 12.6 0.1 0.52 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain SMC_N PF02463.19 KXL43207.1 - 0.14 11.5 0.0 4 6.8 0.1 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain PG_binding_1 PF01471.18 KXL43208.1 - 0.16 12.2 0.1 19 5.6 0.0 3.0 2 0 0 2 2 2 0 Putative peptidoglycan binding domain CLTH PF10607.9 KXL43209.1 - 4.2e-27 94.8 0.0 2.8e-26 92.2 0.0 1.9 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 KXL43209.1 - 9.9e-08 31.9 0.1 2.1e-07 30.9 0.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger RmuC PF02646.16 KXL43209.1 - 0.00042 19.5 0.5 0.00067 18.9 0.5 1.2 1 0 0 1 1 1 1 RmuC family zf-RING_2 PF13639.6 KXL43209.1 - 0.015 15.6 0.2 0.029 14.7 0.2 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 KXL43209.1 - 0.033 14.2 0.8 0.058 13.4 0.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Rtf2 PF04641.12 KXL43209.1 - 0.033 13.6 0.2 0.073 12.4 0.2 1.5 1 0 0 1 1 1 0 Rtf2 RING-finger Phage_Mu_Gam PF07352.12 KXL43209.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein zf-C3HC4 PF00097.25 KXL43209.1 - 0.12 12.3 0.2 0.22 11.4 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXL43209.1 - 0.13 12.1 1.6 0.24 11.3 1.6 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-TRAF PF02176.18 KXL43209.1 - 0.18 12.5 0.3 0.34 11.7 0.3 1.3 1 0 0 1 1 1 0 TRAF-type zinc finger Plasmid_RAQPRD PF09686.10 KXL43209.1 - 1.4 9.2 5.9 0.57 10.4 2.1 2.2 2 1 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) SSF PF00474.17 KXL43211.1 - 1e-17 64.1 32.7 1.7e-17 63.4 32.7 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family ADH_N PF08240.12 KXL43212.1 - 1e-32 112.2 1.1 1.5e-32 111.7 0.2 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXL43212.1 - 2.1e-26 92.4 0.2 3.3e-26 91.8 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXL43212.1 - 7.9e-08 32.0 0.2 1.4e-07 31.3 0.2 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KXL43212.1 - 1.1e-05 24.9 0.9 1.6e-05 24.3 0.9 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KXL43212.1 - 0.0015 18.1 0.0 0.0029 17.2 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_25 PF13649.6 KXL43212.1 - 0.0017 19.0 0.0 0.0033 18.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Pyr_redox_3 PF13738.6 KXL43212.1 - 0.0022 17.3 0.3 0.0037 16.6 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXL43212.1 - 0.0083 15.4 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N_2 PF13602.6 KXL43212.1 - 0.013 16.6 0.0 0.023 15.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase TrkA_N PF02254.18 KXL43212.1 - 0.02 15.1 0.1 0.039 14.2 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain MTS PF05175.14 KXL43212.1 - 0.054 13.0 0.1 0.11 12.1 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 KXL43212.1 - 0.065 13.9 0.0 0.13 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KXL43212.1 - 0.067 13.0 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.19 KXL43212.1 - 0.072 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ferric_reduct PF01794.19 KXL43213.1 - 1.4e-16 60.8 21.8 2.2e-16 60.1 12.6 2.6 2 0 0 2 2 2 2 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXL43213.1 - 2.6e-14 53.6 0.0 4e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXL43213.1 - 3.2e-11 43.3 0.0 7.8e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KXL43213.1 - 0.004 17.8 0.0 0.073 13.7 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain TFB6 PF17110.5 KXL43215.1 - 6.9e-54 182.1 0.0 8.7e-54 181.8 0.0 1.1 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH MIP PF00230.20 KXL43217.1 - 1.9e-24 86.6 2.6 2.4e-24 86.3 2.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein Phage_holin_5_2 PF16079.5 KXL43217.1 - 0.18 12.1 2.1 0.21 11.9 0.1 2.0 2 1 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V Oxidored_molyb PF00174.19 KXL43218.1 - 2.6e-34 118.3 0.0 3.6e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KXL43218.1 - 2e-24 86.2 0.0 3.3e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Glyco_hydro_31 PF01055.26 KXL43219.1 - 1.2e-115 387.2 1.2 1.7e-115 386.8 1.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KXL43219.1 - 5.2e-16 58.7 0.0 1.9e-15 56.9 0.0 2.0 2 0 0 2 2 2 1 Galactose mutarotase-like EHN PF06441.12 KXL43220.1 - 3.9e-31 107.6 0.1 5e-31 107.3 0.1 1.1 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KXL43220.1 - 8.6e-05 22.3 0.1 0.00013 21.7 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXL43220.1 - 0.00091 19.9 0.3 0.0018 19.0 0.3 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family SAM_decarbox PF01536.16 KXL43222.1 - 9.7e-133 442.6 0.0 1.6e-132 441.8 0.0 1.3 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase Peptidase_M16_M PF16187.5 KXL43224.1 - 2.5e-89 299.3 0.1 3.8e-89 298.7 0.1 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 KXL43224.1 - 9e-37 126.9 0.0 1.2e-21 77.6 0.0 3.6 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KXL43224.1 - 5e-34 117.4 0.4 2.1e-33 115.4 0.4 2.1 1 1 0 1 1 1 1 Insulinase (Peptidase family M16) DUF5641 PF18701.1 KXL43224.1 - 0.086 13.0 0.0 0.37 11.0 0.0 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5641) Ribosomal_L27 PF01016.19 KXL43225.1 - 2.6e-28 97.9 0.1 5.1e-28 96.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal L27 protein Ribosomal_L19e PF01280.20 KXL43225.1 - 1.1 9.3 13.2 1.8 8.6 2.9 2.3 2 0 0 2 2 2 0 Ribosomal protein L19e Adap_comp_sub PF00928.21 KXL43226.1 - 9.6e-91 303.8 0.0 1.3e-90 303.4 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KXL43226.1 - 4.4e-10 39.6 0.2 7.2e-10 39.0 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Glyco_transf_21 PF13506.6 KXL43227.1 - 5e-19 68.4 0.2 1.5e-10 40.8 0.0 3.2 2 1 1 3 3 3 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KXL43227.1 - 1.7e-05 24.7 0.0 7.1e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KXL43227.1 - 0.003 17.5 0.0 0.0076 16.2 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Filament PF00038.21 KXL43228.1 - 3 7.3 56.3 15 5.1 46.8 3.1 1 1 0 2 2 2 0 Intermediate filament protein Nop10p PF04135.12 KXL43230.1 - 5.2e-21 74.4 0.3 6.4e-21 74.1 0.3 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family NOB1_Zn_bind PF08772.11 KXL43231.1 - 4.2e-33 113.3 2.9 7.8e-33 112.5 2.9 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 KXL43231.1 - 5.5e-30 103.7 0.8 2.4e-29 101.7 0.3 2.1 2 0 0 2 2 2 1 PIN domain of ribonuclease zf-NADH-PPase PF09297.11 KXL43231.1 - 0.0027 17.4 2.6 0.0057 16.3 0.6 2.2 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain HypA PF01155.19 KXL43231.1 - 0.051 13.6 0.2 0.12 12.4 0.2 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 KXL43231.1 - 0.076 13.0 1.2 0.18 11.8 1.2 1.6 1 0 0 1 1 1 0 zinc-ribbons DUF2616 PF11077.8 KXL43231.1 - 0.08 12.7 0.2 0.14 11.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) DUF2321 PF10083.9 KXL43231.1 - 0.097 12.3 0.2 0.24 11.0 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Zn-ribbon_8 PF09723.10 KXL43231.1 - 0.1 12.7 3.2 0.087 13.0 1.3 2.0 2 0 0 2 2 2 0 Zinc ribbon domain DZR PF12773.7 KXL43231.1 - 0.11 12.5 1.9 0.25 11.4 1.9 1.5 1 0 0 1 1 1 0 Double zinc ribbon PH PF00169.29 KXL43233.1 - 1.4e-05 25.6 0.5 3.5e-05 24.3 0.5 1.6 1 0 0 1 1 1 1 PH domain TAF6_C PF07571.13 KXL43236.1 - 1.1e-27 96.1 0.0 2.8e-27 94.9 0.0 1.7 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 KXL43236.1 - 1.4e-24 86.0 0.0 6e-24 84.0 0.2 2.0 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 KXL43236.1 - 6.9e-06 26.5 0.5 0.00015 22.1 0.3 2.3 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXL43236.1 - 9.2e-05 22.7 0.1 0.00094 19.4 0.1 2.3 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KXL43236.1 - 0.012 15.7 0.4 0.033 14.3 0.4 1.7 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.6 KXL43236.1 - 0.031 14.6 0.1 0.11 12.9 0.1 1.9 1 0 0 1 1 1 0 CENP-S protein CENP-T_C PF15511.6 KXL43236.1 - 0.23 11.6 0.8 6.9 6.8 0.1 2.8 3 0 0 3 3 3 0 Centromere kinetochore component CENP-T histone fold DUF2076 PF09849.9 KXL43237.1 - 0.0017 18.5 7.1 0.0025 17.9 7.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) MFS_1 PF07690.16 KXL43238.1 - 1.9e-48 165.2 32.4 1.9e-48 165.2 32.4 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL43238.1 - 2.4e-13 49.8 13.0 2.4e-13 49.8 13.0 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 KXL43238.1 - 1.9e-07 30.7 4.3 1.9e-07 30.7 4.3 2.2 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 KXL43238.1 - 3.4e-07 29.1 1.8 5.1e-07 28.5 1.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KXL43238.1 - 6.4e-05 21.5 1.1 0.0001 20.9 1.1 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.20 KXL43238.1 - 7.3e-05 21.3 6.4 7.3e-05 21.3 6.4 2.0 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family TMEM247 PF15444.6 KXL43238.1 - 0.025 14.6 0.1 0.049 13.7 0.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 247 NDK PF00334.19 KXL43239.1 - 4.1e-53 179.0 0.0 4.6e-53 178.8 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glyco_hydro_31 PF01055.26 KXL43240.1 - 9.2e-140 466.7 4.4 1.3e-139 466.2 4.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KXL43240.1 - 3e-24 85.1 0.6 1.2e-22 80.0 0.2 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KXL43240.1 - 6.8e-08 32.7 0.2 5.3e-07 29.8 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) DUF364 PF04016.12 KXL43240.1 - 0.026 14.1 0.1 20 4.7 0.0 3.1 3 0 0 3 3 3 0 Putative heavy-metal chelation Cnd3 PF12719.7 KXL43242.1 - 9.8e-86 287.6 8.6 1.3e-85 287.1 5.7 2.3 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 KXL43242.1 - 1.9e-09 37.8 8.8 0.00035 20.9 3.4 5.1 3 2 2 5 5 5 4 HEAT repeats HEAT PF02985.22 KXL43242.1 - 1.1e-07 31.5 4.5 0.21 11.9 0.0 6.5 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 KXL43242.1 - 5.6e-06 26.5 1.9 0.19 11.7 0.1 4.5 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KXL43242.1 - 0.00011 22.7 4.5 0.81 10.3 0.0 5.4 3 1 2 5 5 5 2 HEAT-like repeat RTP1_C1 PF10363.9 KXL43242.1 - 0.11 12.7 0.3 7.8 6.7 0.0 3.2 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 PALP PF00291.25 KXL43243.1 - 3.1e-69 233.6 0.1 4e-69 233.3 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Fungal_trans PF04082.18 KXL43244.1 - 1.2e-14 54.0 0.0 2.4e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL43244.1 - 2.8e-08 33.7 5.8 5.4e-08 32.8 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytomega_gL PF01801.16 KXL43244.1 - 0.0097 15.3 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 1 Cytomegalovirus glycoprotein L Ank_2 PF12796.7 KXL43245.1 - 1e-22 80.5 0.5 2.1e-12 47.4 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXL43245.1 - 1.5e-12 47.8 0.0 1.6e-08 35.0 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KXL43245.1 - 9.9e-11 41.6 0.1 9.4e-08 32.2 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KXL43245.1 - 1.4e-10 40.4 0.1 4.8e-06 26.5 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KXL43245.1 - 2.8e-08 33.8 0.4 1.9e-06 28.1 0.1 2.7 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Abhydrolase_4 PF08386.10 KXL43245.1 - 0.053 13.6 0.0 2.3 8.4 0.0 2.3 2 0 0 2 2 2 0 TAP-like protein PQ-loop PF04193.14 KXL43246.1 - 7.1e-40 134.6 17.0 6.5e-22 77.1 1.7 2.6 3 0 0 3 3 3 2 PQ loop repeat COX1 PF00115.20 KXL43246.1 - 0.0087 15.0 2.2 0.018 13.9 0.0 2.1 2 0 0 2 2 2 1 Cytochrome C and Quinol oxidase polypeptide I AcrZ PF10766.9 KXL43246.1 - 0.11 12.1 0.2 0.4 10.3 0.2 1.9 1 0 0 1 1 1 0 Multidrug efflux pump-associated protein AcrZ ParA PF10609.9 KXL43247.1 - 5.7e-91 304.3 0.2 5.7e-88 294.5 0.2 2.0 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KXL43247.1 - 4.6e-14 52.6 0.0 2.4e-12 47.0 0.0 2.1 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 KXL43247.1 - 4.1e-07 29.5 0.4 2.8e-05 23.5 0.2 2.2 2 0 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 KXL43247.1 - 4.8e-07 29.3 0.0 3.3e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.6 KXL43247.1 - 1.1e-05 25.4 0.3 8.4e-05 22.6 0.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_26 PF13500.6 KXL43247.1 - 0.00012 21.9 1.0 0.014 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 KXL43247.1 - 0.0018 17.3 0.2 0.0029 16.6 0.2 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 KXL43247.1 - 0.0019 17.8 0.6 0.0036 16.9 0.1 1.6 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 KXL43247.1 - 0.014 15.3 0.1 0.023 14.6 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase CBP_BcsQ PF06564.12 KXL43247.1 - 0.015 14.8 0.1 0.071 12.6 0.0 1.8 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ Zeta_toxin PF06414.12 KXL43247.1 - 0.026 13.8 0.0 0.055 12.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RsgA_GTPase PF03193.16 KXL43247.1 - 0.14 12.0 1.5 0.48 10.3 0.9 1.9 2 0 0 2 2 2 0 RsgA GTPase CLP1_P PF16575.5 KXL43247.1 - 0.17 11.6 0.2 0.47 10.2 0.1 1.7 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop SRP54 PF00448.22 KXL43247.1 - 0.18 11.4 0.2 0.93 9.1 0.2 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 KXL43247.1 - 0.19 10.9 0.2 0.29 10.3 0.2 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 KXL43247.1 - 0.24 11.7 0.4 0.61 10.5 0.3 1.7 2 0 0 2 2 2 0 AAA ATPase domain Thymidylate_kin PF02223.17 KXL43250.1 - 7.2e-35 120.3 0.0 8.9e-35 120.0 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.10 KXL43250.1 - 0.0036 16.8 0.0 0.0061 16.1 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 KXL43250.1 - 0.017 15.7 0.1 0.14 12.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KXL43250.1 - 0.088 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase CLP1_P PF16575.5 KXL43250.1 - 0.15 11.9 0.0 9.3 6.0 0.0 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop TGT PF01702.18 KXL43251.1 - 2.8e-41 141.8 0.0 3.6e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase GDPD_2 PF13653.6 KXL43252.1 - 0.0015 18.9 0.4 0.0031 17.9 0.4 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family p450 PF00067.22 KXL43253.1 - 1.8e-20 73.2 0.0 2.6e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Proteasome PF00227.26 KXL43254.1 - 4.6e-49 166.5 0.2 2.1e-39 135.0 0.1 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KXL43254.1 - 1.6e-15 56.5 0.6 2.4e-12 46.3 0.1 2.7 2 0 0 2 2 2 2 Proteasome subunit A N-terminal signature TGBp3 PF02495.17 KXL43254.1 - 0.075 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Triple gene block 3 tRNA_NucTran2_2 PF13735.6 KXL43254.1 - 0.15 12.1 0.1 0.25 11.3 0.1 1.3 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative zf-RanBP PF00641.18 KXL43255.1 - 1.5e-20 72.2 10.9 1.9e-11 43.1 1.1 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.7 KXL43255.1 - 1.9 8.6 7.6 2.5 8.2 1.1 2.3 2 0 0 2 2 2 0 Double zinc ribbon TackOD1 PF18551.1 KXL43255.1 - 2.9 7.5 4.9 14 5.3 0.6 2.1 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 Rubredoxin PF00301.20 KXL43255.1 - 6 7.0 7.6 0.58 10.2 1.1 2.4 2 1 0 2 2 2 0 Rubredoxin adh_short PF00106.25 KXL43256.1 - 6e-36 123.7 0.3 7.8e-36 123.4 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL43256.1 - 4.5e-25 88.6 0.1 6.8e-25 88.0 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL43256.1 - 9e-07 29.0 0.5 7e-06 26.1 0.5 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL43256.1 - 0.0012 18.4 0.0 0.0022 17.5 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXL43256.1 - 0.0028 17.6 0.0 0.0043 17.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXL43256.1 - 0.028 13.4 0.1 0.046 12.7 0.1 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXL43256.1 - 0.037 13.4 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF4345 PF14248.6 KXL43256.1 - 0.15 11.9 1.1 0.5 10.3 0.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4345) GTP1_OBG PF01018.22 KXL43257.1 - 8.2e-39 132.7 1.5 1.1e-28 99.8 3.6 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 KXL43257.1 - 6.3e-24 84.3 0.0 1.2e-23 83.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXL43257.1 - 1.1e-06 28.3 0.0 3e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_33 PF13671.6 KXL43257.1 - 0.027 14.7 0.1 0.14 12.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 KXL43257.1 - 0.03 13.3 0.0 0.32 9.9 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 KXL43257.1 - 0.032 14.7 0.0 0.061 13.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 KXL43257.1 - 0.091 13.3 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 KXL43257.1 - 0.12 11.9 0.0 0.55 9.7 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family Dynamin_N PF00350.23 KXL43257.1 - 0.22 11.6 0.0 4.5 7.3 0.0 2.6 2 1 0 3 3 3 0 Dynamin family NUMOD3 PF07460.11 KXL43259.1 - 0.5 10.6 2.3 1.8 8.9 0.2 2.7 2 1 1 3 3 3 0 NUMOD3 motif (2 copies) T5orf172 PF10544.9 KXL43260.1 - 5.5e-24 84.7 0.2 1.5e-23 83.3 0.2 1.7 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 KXL43260.1 - 2.2e-23 82.7 0.2 3.8e-23 81.9 0.2 1.4 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 zf-NADH-PPase PF09297.11 KXL43260.1 - 0.46 10.2 3.7 0.53 10.0 0.4 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain UQ_con PF00179.26 KXL43261.1 - 6.2e-41 139.3 0.0 8.2e-41 138.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 KXL43261.1 - 9.4e-05 22.1 0.0 0.00016 21.4 0.0 1.3 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.6 KXL43261.1 - 0.012 15.3 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 KXL43261.1 - 0.067 13.5 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 RWD domain UBA PF00627.31 KXL43261.1 - 0.14 12.1 0.1 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 UBA/TS-N domain DUF1421 PF07223.11 KXL43261.1 - 0.17 11.8 0.3 0.32 10.9 0.3 1.4 1 0 0 1 1 1 0 UBA-like domain (DUF1421) AAA PF00004.29 KXL43262.1 - 1.8e-40 138.4 0.0 3.2e-40 137.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXL43262.1 - 6.3e-11 41.9 0.6 1.3e-10 40.9 0.6 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KXL43262.1 - 1.2e-09 37.9 0.1 2.4e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 KXL43262.1 - 2e-06 28.1 0.2 0.02 15.1 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.14 KXL43262.1 - 8.4e-06 26.0 0.0 1.7e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KXL43262.1 - 1.1e-05 24.7 0.0 1.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 KXL43262.1 - 9.2e-05 22.5 0.1 0.00029 20.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXL43262.1 - 0.00011 22.6 0.5 0.0017 18.7 0.4 2.3 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KXL43262.1 - 0.00041 20.1 0.0 0.00076 19.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KXL43262.1 - 0.0032 17.7 0.8 0.0071 16.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KXL43262.1 - 0.0082 16.7 0.0 0.018 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXL43262.1 - 0.0092 16.1 0.1 0.026 14.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 KXL43262.1 - 0.014 15.2 0.0 0.041 13.7 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KXL43262.1 - 0.016 14.9 0.0 0.04 13.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 KXL43262.1 - 0.017 14.4 0.1 0.041 13.1 0.1 1.7 1 1 0 1 1 1 0 TIP49 P-loop domain ATPase PF06745.13 KXL43262.1 - 0.024 14.0 0.2 0.53 9.6 0.1 2.2 1 1 0 2 2 2 0 KaiC AAA_14 PF13173.6 KXL43262.1 - 0.037 14.1 0.0 0.072 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXL43262.1 - 0.042 13.8 0.2 0.68 9.8 0.1 2.3 1 1 1 2 2 2 0 NACHT domain RNA_helicase PF00910.22 KXL43262.1 - 0.054 13.9 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KXL43262.1 - 0.061 12.7 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KXL43262.1 - 0.074 12.6 1.8 0.59 9.7 0.4 2.6 1 1 0 2 2 2 0 AAA domain PhoH PF02562.16 KXL43262.1 - 0.087 12.3 0.3 0.52 9.7 0.1 2.0 2 0 0 2 2 2 0 PhoH-like protein Zeta_toxin PF06414.12 KXL43262.1 - 0.088 12.1 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Prot_ATP_OB_N PF17758.1 KXL43262.1 - 0.1 12.3 0.6 1 9.0 0.0 2.6 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain AAA_24 PF13479.6 KXL43262.1 - 0.16 11.6 0.3 0.33 10.7 0.3 1.6 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KXL43262.1 - 0.18 11.0 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KXL43262.1 - 0.2 11.1 0.1 0.53 9.8 0.1 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region TRAPP PF04051.16 KXL43263.1 - 2.1e-44 150.8 0.0 2.7e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF2378 PF09536.10 KXL43263.1 - 0.047 13.6 0.0 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2378) Mg_trans_NIPA PF05653.14 KXL43264.1 - 1.6e-59 201.4 9.8 3.4e-56 190.5 7.1 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 KXL43264.1 - 0.00031 20.9 1.6 0.00031 20.9 1.6 3.7 3 1 0 3 3 3 2 EamA-like transporter family DUF1345 PF07077.11 KXL43264.1 - 0.024 14.3 1.0 1.6 8.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1345) DUF1461 PF07314.11 KXL43264.1 - 2.9 7.8 6.1 0.83 9.5 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) DUF1772 PF08592.11 KXL43264.1 - 3.8 7.8 12.1 36 4.7 0.0 3.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) UCH_1 PF13423.6 KXL43265.1 - 9.4e-15 55.0 0.0 2.9e-12 46.8 0.0 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L5_C PF00673.21 KXL43267.1 - 7.6e-30 102.9 0.0 1.3e-29 102.2 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KXL43267.1 - 1.8e-14 53.8 0.1 3.4e-14 52.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 Androgen_recep PF02166.16 KXL43267.1 - 0.36 9.6 0.0 0.36 9.6 0.0 2.2 2 1 0 2 2 2 0 Androgen receptor WHIM1 PF15612.6 KXL43268.1 - 1.3e-05 24.6 0.0 3.1e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 TFIIA PF03153.13 KXL43268.1 - 0.19 11.7 12.2 0.016 15.2 7.3 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ribosomal_L2_C PF03947.18 KXL43269.1 - 2.4e-41 140.9 5.1 2.4e-41 140.9 5.1 1.6 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KXL43269.1 - 3.7e-15 55.6 0.2 9.3e-15 54.4 0.2 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain BAR PF03114.18 KXL43270.1 - 4.9e-42 144.2 6.6 6.1e-42 143.9 6.6 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 KXL43270.1 - 0.1 11.7 8.7 0.033 13.3 5.7 1.4 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking CAP_N PF01213.19 KXL43270.1 - 5.5 6.4 10.9 3.7 7.0 5.6 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 KXL43270.1 - 8.2 6.5 7.7 29 4.7 7.7 1.9 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Anp1 PF03452.14 KXL43273.1 - 1.2e-30 106.8 0.1 1.9e-30 106.2 0.1 1.2 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 KXL43273.1 - 0.068 13.0 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Zn_clus PF00172.18 KXL43275.1 - 3.2e-07 30.4 9.2 4.7e-07 29.8 9.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXL43275.1 - 0.0002 20.3 0.0 0.00027 19.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.13 KXL43276.1 - 2.1e-70 236.6 7.7 2.1e-70 236.6 7.7 1.4 2 0 0 2 2 2 1 RTA1 like protein FtsX PF02687.21 KXL43277.1 - 0.02 15.4 3.9 0.029 14.8 3.9 1.2 1 0 0 1 1 1 0 FtsX-like permease family MHC2-interact PF09307.10 KXL43277.1 - 0.021 14.8 0.0 0.038 14.0 0.0 1.6 1 0 0 1 1 1 0 CLIP, MHC2 interacting Wzz PF02706.15 KXL43277.1 - 0.031 14.6 0.1 0.031 14.6 0.1 1.6 2 0 0 2 2 2 0 Chain length determinant protein Zn_peptidase PF04228.13 KXL43277.1 - 0.11 12.0 0.2 0.19 11.1 0.2 1.4 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase SecG PF03840.14 KXL43277.1 - 1 9.5 7.7 1.9 8.6 7.7 1.5 1 0 0 1 1 1 0 Preprotein translocase SecG subunit DUF2749 PF10907.8 KXL43277.1 - 1.1 9.4 8.4 5 7.4 2.9 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2749) zf-Nse PF11789.8 KXL43278.1 - 3.6e-23 81.1 0.6 6.1e-23 80.4 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KXL43278.1 - 2.3e-05 24.3 0.1 4.5e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXL43278.1 - 0.0028 17.5 0.0 0.0071 16.2 0.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Transpos_assoc PF13963.6 KXL43278.1 - 0.071 13.4 0.9 0.16 12.3 0.2 1.9 2 0 0 2 2 2 0 Transposase-associated domain MtrG PF04210.13 KXL43278.1 - 0.12 12.3 0.1 0.5 10.3 0.0 2.1 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G zf-MIZ PF02891.20 KXL43278.1 - 0.12 12.1 0.6 0.24 11.2 0.6 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger COG2 PF06148.11 KXL43278.1 - 0.26 11.4 4.5 1.5 8.9 1.2 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ISG65-75 PF11727.8 KXL43278.1 - 0.44 9.7 5.0 1.2 8.3 0.8 2.2 1 1 1 2 2 2 0 Invariant surface glycoprotein V_ATPase_I PF01496.19 KXL43278.1 - 4.4 5.1 5.0 6.7 4.5 5.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mito_carr PF00153.27 KXL43279.1 - 6.5e-53 176.6 2.1 2.5e-18 65.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXL43279.1 - 0.066 12.4 1.2 0.14 11.3 0.4 2.1 1 1 1 2 2 2 0 Gammaproteobacterial serine protease TMF_DNA_bd PF12329.8 KXL43280.1 - 0.0072 16.3 1.2 0.0072 16.3 1.2 10.0 6 2 8 14 14 14 1 TATA element modulatory factor 1 DNA binding DUF1699 PF08004.11 KXL43280.1 - 0.94 9.2 9.3 0.099 12.3 1.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1699) Ribosomal_L33 PF00471.20 KXL43281.1 - 5.1e-06 26.8 0.2 5.9e-06 26.6 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 PEX11 PF05648.14 KXL43282.1 - 2.1e-69 233.4 1.3 2.4e-69 233.2 1.3 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) HP1451_C PF18472.1 KXL43285.1 - 0.048 13.7 0.4 1.2 9.1 0.1 2.9 3 0 0 3 3 3 0 HP1451 C-terminal domain Isochorismatase PF00857.20 KXL43286.1 - 1.1e-21 77.8 0.0 1.3e-21 77.6 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family T5orf172 PF10544.9 KXL43288.1 - 7.1e-11 42.6 1.1 1.4e-10 41.6 0.1 2.0 2 0 0 2 2 2 1 T5orf172 domain MUG113 PF13455.6 KXL43288.1 - 0.00016 22.3 0.4 0.0006 20.4 0.4 2.0 1 1 0 1 1 1 1 Meiotically up-regulated gene 113 Tox-URI2 PF15653.6 KXL43288.1 - 0.026 14.8 0.2 0.33 11.2 0.0 2.4 2 0 0 2 2 2 0 URI fold toxin 2 TRAUB PF08164.12 KXL43289.1 - 2.9e-28 98.2 0.8 2.9e-28 98.2 0.8 2.4 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 KXL43289.1 - 3.4e-26 92.6 1.8 3.4e-26 92.6 1.8 3.3 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor FAD_binding_3 PF01494.19 KXL43293.1 - 1.9e-71 241.2 0.0 2.9e-71 240.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KXL43293.1 - 7.1e-45 153.0 0.0 3.1e-44 150.9 0.0 2.0 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.17 KXL43293.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 KXL43293.1 - 0.096 11.9 0.0 0.49 9.6 0.0 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase LOR PF04525.12 KXL43294.1 - 1.6e-06 27.8 0.1 2.2e-06 27.4 0.1 1.3 1 1 0 1 1 1 1 LURP-one-related Rrn6 PF10214.9 KXL43295.1 - 0.041 12.4 10.1 0.056 11.9 10.1 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF4746 PF15928.5 KXL43295.1 - 0.79 9.1 6.9 1.2 8.5 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Hydin_ADK PF17213.3 KXL43295.1 - 4 7.7 6.6 4.4 7.5 5.1 1.8 1 1 1 2 2 2 0 Hydin Adenylate kinase-like domain Macoilin PF09726.9 KXL43295.1 - 4.6 5.7 12.0 7.7 4.9 12.0 1.3 1 0 0 1 1 1 0 Macoilin family Borrelia_P83 PF05262.11 KXL43295.1 - 8.1 4.8 10.9 12 4.3 10.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein GrpB PF04229.14 KXL43299.1 - 2.1e-51 174.3 0.0 2.5e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 GrpB protein DHHC PF01529.20 KXL43300.1 - 1.2e-37 129.0 3.4 1.2e-37 129.0 3.4 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase Spt4 PF06093.13 KXL43300.1 - 1.3 9.1 5.9 3 8.0 5.9 1.6 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger Peptidase_S24 PF00717.23 KXL43301.1 - 8.7e-07 28.8 0.0 1.4e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KXL43301.1 - 2.6e-05 24.0 0.0 0.00056 19.7 0.0 2.2 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 Dynamin_N PF00350.23 KXL43302.1 - 3.1e-45 154.2 0.0 5.3e-45 153.5 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KXL43302.1 - 3.7e-12 46.0 0.0 8.2e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 KXL43302.1 - 0.00011 22.2 0.0 0.00043 20.3 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KXL43302.1 - 0.0084 16.5 0.0 0.036 14.4 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 KXL43302.1 - 0.052 13.3 0.1 0.31 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 KXL43302.1 - 0.058 13.2 0.0 0.25 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Coat_F PF07875.12 KXL43302.1 - 0.065 13.5 0.4 4.9 7.5 0.1 3.1 2 0 0 2 2 2 0 Coat F domain Aa_trans PF01490.18 KXL43303.1 - 2.3e-25 89.1 32.4 3.4e-25 88.6 32.4 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Glyco_hydro_88 PF07470.13 KXL43304.1 - 4.5e-09 35.8 1.0 1.1e-08 34.6 0.9 1.6 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 GFA PF04828.14 KXL43305.1 - 7.1e-25 87.2 0.3 9.2e-25 86.8 0.3 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Asp_Arg_Hydrox PF05118.15 KXL43306.1 - 0.05 13.4 0.5 0.095 12.5 0.5 1.5 1 1 0 1 1 1 0 Aspartyl/Asparaginyl beta-hydroxylase DUF3886 PF13025.6 KXL43307.1 - 0.0061 16.7 1.3 0.0073 16.5 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3886) Sugar_tr PF00083.24 KXL43308.1 - 3.1e-79 266.9 22.5 3.6e-79 266.7 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL43308.1 - 1.6e-16 60.2 29.8 2.8e-15 56.1 25.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KXL43308.1 - 9.4e-05 21.9 5.0 9.4e-05 21.9 5.0 1.9 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB CcmD PF04995.14 KXL43308.1 - 0.038 14.1 0.4 0.038 14.1 0.4 3.6 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) MFS_3 PF05977.13 KXL43308.1 - 0.5 8.7 11.3 0.0095 14.4 3.7 1.8 2 0 0 2 2 2 0 Transmembrane secretion effector VIT1 PF01988.19 KXL43308.1 - 1.8 8.4 8.6 3.4 7.5 3.8 2.7 2 1 0 2 2 2 0 VIT family HTH_psq PF05225.16 KXL43309.1 - 0.096 12.4 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Melibiase_2 PF16499.5 KXL43310.1 - 1.6e-62 211.3 3.7 1e-60 205.3 3.7 2.3 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KXL43310.1 - 4.7e-12 45.8 0.1 2.1e-10 40.5 0.1 2.5 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KXL43310.1 - 8.1e-08 31.6 0.0 7.4e-07 28.4 0.0 2.0 2 0 0 2 2 2 1 Melibiase Zn_clus PF00172.18 KXL43311.1 - 6.2e-06 26.2 8.5 1.1e-05 25.4 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXL43311.1 - 0.0011 18.1 0.5 0.0019 17.3 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain SelP_N PF04592.14 KXL43312.1 - 0.0084 15.5 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Selenoprotein P, N terminal region Transket_pyr PF02779.24 KXL43313.1 - 9e-49 165.6 0.0 1.3e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KXL43313.1 - 2.9e-34 117.6 0.0 8.4e-34 116.1 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain zinc_ribbon_12 PF11331.8 KXL43314.1 - 0.13 12.1 2.6 0.18 11.7 0.2 2.2 2 0 0 2 2 2 0 Probable zinc-ribbon domain Pterin_4a PF01329.19 KXL43316.1 - 8.8e-25 86.7 0.6 1.3e-24 86.2 0.6 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase BKACE PF05853.12 KXL43316.1 - 0.1 11.9 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme Sterol_MT_C PF08498.10 KXL43317.1 - 2.9e-30 104.4 0.2 4.8e-30 103.7 0.2 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 KXL43317.1 - 5.2e-20 71.9 0.0 9.1e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL43317.1 - 1.3e-18 67.4 0.0 2.8e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL43317.1 - 5.3e-17 62.0 0.0 8.1e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXL43317.1 - 1.3e-12 47.7 0.0 1.9e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KXL43317.1 - 1.2e-11 44.7 0.0 2e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL43317.1 - 5.2e-09 36.8 0.0 1.2e-08 35.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXL43317.1 - 5.4e-09 35.7 0.0 8.7e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 KXL43317.1 - 4.8e-05 22.1 0.0 7.7e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PrmA PF06325.13 KXL43317.1 - 0.00016 21.2 0.1 0.00041 19.8 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 KXL43317.1 - 0.0013 18.5 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 KXL43317.1 - 0.0019 17.3 0.0 0.003 16.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.14 KXL43317.1 - 0.0024 17.4 0.1 0.0067 16.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain MetW PF07021.12 KXL43317.1 - 0.0069 16.0 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 KXL43317.1 - 0.012 15.6 0.1 0.029 14.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_2 PF00891.18 KXL43317.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_15 PF09445.10 KXL43317.1 - 0.036 13.6 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_3 PF01596.17 KXL43317.1 - 0.13 11.4 0.0 0.25 10.5 0.0 1.5 1 1 0 1 1 1 0 O-methyltransferase RRM_1 PF00076.22 KXL43318.1 - 1.3e-06 28.1 0.0 2.4e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXL43318.1 - 0.0052 16.8 0.0 0.0096 15.9 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif FA_hydroxylase PF04116.13 KXL43319.1 - 4.3e-23 82.1 10.2 4.3e-23 82.1 10.2 2.5 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Thioredoxin_8 PF13905.6 KXL43319.1 - 0.017 15.4 0.0 0.059 13.7 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like RAC_head PF16717.5 KXL43320.1 - 2.3e-29 102.3 5.4 2.3e-29 102.3 5.4 3.2 3 1 0 3 3 3 1 Ribosome-associated complex head domain DnaJ PF00226.31 KXL43320.1 - 1.6e-19 69.7 0.2 6.7e-19 67.8 0.2 2.2 1 0 0 1 1 1 1 DnaJ domain V_ATPase_I PF01496.19 KXL43320.1 - 0.49 8.2 12.2 0.9 7.4 12.2 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.16 KXL43320.1 - 2.5 6.9 7.8 2.8 6.8 7.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein NPCC PF08058.11 KXL43322.1 - 9.1e-25 87.2 0.0 1.4e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 Nuclear pore complex component Cyt-b5 PF00173.28 KXL43323.1 - 2.1e-18 66.2 1.2 3.4e-18 65.6 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 KXL43323.1 - 9.7e-13 48.6 21.0 9.7e-13 48.6 21.0 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 KXL43323.1 - 0.033 14.4 0.2 0.083 13.1 0.2 1.6 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region Hydrolase_4 PF12146.8 KXL43324.1 - 0.016 14.5 0.0 0.16 11.2 0.0 2.3 2 1 0 2 2 2 0 Serine aminopeptidase, S33 DUF3455 PF11937.8 KXL43325.1 - 1.8e-30 106.4 1.0 2.2e-30 106.1 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) COesterase PF00135.28 KXL43326.1 - 6.8e-57 193.5 0.0 4.6e-56 190.7 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXL43326.1 - 0.00073 19.4 0.0 0.22 11.3 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Ceramidase_alk PF04734.13 KXL43327.1 - 2.9e-215 715.7 0.0 3.4e-215 715.5 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KXL43327.1 - 1.3e-54 184.5 0.0 2.1e-54 183.9 0.0 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal BCAS2 PF05700.11 KXL43328.1 - 2.5e-52 177.6 5.6 2.8e-52 177.4 5.6 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) DUF4558 PF15104.6 KXL43328.1 - 0.4 10.8 7.6 5.9 7.0 0.0 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4558) FliJ PF02050.16 KXL43328.1 - 3.8 7.7 12.4 0.24 11.6 5.6 2.3 3 0 0 3 3 3 0 Flagellar FliJ protein AMPK1_CBM PF16561.5 KXL43330.1 - 6.4e-23 80.8 0.5 1.1e-22 80.0 0.5 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 KXL43330.1 - 0.011 16.1 0.1 0.022 15.1 0.1 1.4 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) CBM53 PF16760.5 KXL43330.1 - 0.026 15.1 0.2 0.06 13.9 0.2 1.5 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) CFEM PF05730.11 KXL43331.1 - 1.4e-14 53.9 7.7 2.3e-14 53.2 7.7 1.3 1 0 0 1 1 1 1 CFEM domain HbrB PF08539.11 KXL43332.1 - 1.5e-54 184.5 0.0 2.9e-54 183.6 0.0 1.5 1 0 0 1 1 1 1 HbrB-like Clat_adaptor_s PF01217.20 KXL43335.1 - 4.4e-44 149.9 0.0 7.1e-44 149.2 0.0 1.3 1 1 0 1 1 1 1 Clathrin adaptor complex small chain PDDEXK_7 PF04411.12 KXL43336.1 - 0.2 11.7 1.6 2.8 7.9 0.2 2.3 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily LMBR1 PF04791.16 KXL43336.1 - 0.3 10.0 0.1 0.29 10.0 0.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Abhydrolase_3 PF07859.13 KXL43338.1 - 6.2e-33 114.4 0.0 9.6e-23 81.1 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF1741 PF08427.10 KXL43339.1 - 2.9e-73 246.4 5.1 5.8e-73 245.4 5.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) Dymeclin PF09742.9 KXL43339.1 - 0.042 12.3 8.1 0.12 10.8 6.6 2.3 2 1 0 2 2 2 0 Dyggve-Melchior-Clausen syndrome protein DUF2178 PF09946.9 KXL43339.1 - 0.095 12.9 0.1 0.72 10.1 0.0 2.4 3 0 0 3 3 3 0 Predicted membrane protein (DUF2178) DUF726 PF05277.12 KXL43340.1 - 8.7e-126 419.5 4.4 1.4e-125 418.8 4.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.20 KXL43340.1 - 6.7e-05 23.1 0.0 0.00023 21.4 0.0 1.8 1 0 0 1 1 1 1 Thioesterase domain B12-binding PF02310.19 KXL43340.1 - 0.045 13.8 0.0 0.14 12.2 0.0 1.9 1 0 0 1 1 1 0 B12 binding domain Abhydrolase_6 PF12697.7 KXL43340.1 - 0.2 12.3 1.4 0.82 10.2 0.1 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Methyltransf_23 PF13489.6 KXL43341.1 - 2.3e-19 69.8 0.0 4.6e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL43341.1 - 2e-12 47.7 0.0 5.9e-12 46.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL43341.1 - 2.9e-10 40.7 0.0 8e-10 39.2 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL43341.1 - 3.2e-09 36.7 0.0 2.7e-08 33.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL43341.1 - 2.1e-08 34.8 0.0 1.5e-07 32.0 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXL43341.1 - 0.00054 19.4 0.0 0.0075 15.6 0.0 2.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KXL43341.1 - 0.00064 19.2 0.0 0.00093 18.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 KXL43341.1 - 0.0038 16.5 0.0 0.0092 15.3 0.0 1.6 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 KXL43341.1 - 0.0049 16.4 0.0 0.011 15.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_16 PF10294.9 KXL43341.1 - 0.015 15.0 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_4 PF02390.17 KXL43341.1 - 0.093 12.2 0.0 0.21 11.0 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase DUF938 PF06080.12 KXL43341.1 - 0.17 11.6 0.0 0.31 10.8 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF938) NUDIX PF00293.28 KXL43342.1 - 2.7e-16 59.8 3.7 3.2e-16 59.6 3.7 1.1 1 0 0 1 1 1 1 NUDIX domain Mob1_phocein PF03637.17 KXL43344.1 - 2.8e-68 229.2 0.0 3.7e-68 228.8 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family Sugar_tr PF00083.24 KXL43345.1 - 2.1e-85 287.3 23.2 2.5e-85 287.1 23.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL43345.1 - 2.2e-13 49.9 33.6 1.4e-08 34.0 11.9 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily BatA PF07584.11 KXL43345.1 - 0.22 11.9 1.4 0.4 11.1 0.0 2.1 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal PAF-AH_p_II PF03403.13 KXL43346.1 - 2.2e-38 131.8 0.0 1.6e-37 128.9 0.0 1.9 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KXL43346.1 - 2.2e-08 33.3 0.0 4.1e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KXL43346.1 - 5.5e-05 22.6 0.2 0.011 15.0 0.0 2.5 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXL43346.1 - 8.1e-05 23.3 0.1 0.00018 22.2 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 KXL43346.1 - 0.0052 15.8 0.0 0.0096 15.0 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_2 PF02230.16 KXL43346.1 - 0.055 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KXL43346.1 - 0.07 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Fringe PF02434.16 KXL43347.1 - 0.00043 19.8 2.3 0.022 14.2 0.2 3.3 3 1 0 3 3 3 1 Fringe-like U79_P34 PF03064.16 KXL43349.1 - 0.91 8.8 11.5 1.4 8.2 11.5 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DDRGK PF09756.9 KXL43349.1 - 3.1 7.3 19.9 5.5 6.5 19.9 1.3 1 0 0 1 1 1 0 DDRGK domain Zn_clus PF00172.18 KXL43351.1 - 4.7e-08 33.0 9.1 1.2e-07 31.7 9.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_N_3 PF13417.6 KXL43352.1 - 1.6e-14 54.1 0.0 2.5e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXL43352.1 - 3.9e-13 49.5 0.0 6.2e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXL43352.1 - 1.9e-08 34.4 0.0 3.2e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXL43352.1 - 2.9e-08 33.8 0.0 5.4e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXL43352.1 - 8.3e-08 32.1 0.1 1.3e-07 31.5 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXL43352.1 - 6.4e-06 26.3 0.0 1.2e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ADH_zinc_N PF00107.26 KXL43353.1 - 9.5e-07 28.9 0.5 1.6e-05 24.9 0.5 2.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXL43353.1 - 0.0065 15.8 0.1 0.0099 15.2 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 KXL43353.1 - 0.061 12.8 0.1 0.096 12.1 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase ADH_N PF08240.12 KXL43353.1 - 0.066 13.1 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Gon7 PF08738.10 KXL43354.1 - 9.8e-11 41.7 2.4 1.1e-10 41.6 1.7 1.4 1 1 1 2 2 2 1 Gon7 family DUF4611 PF15387.6 KXL43354.1 - 0.031 14.5 2.7 0.04 14.1 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NOP19 PF10863.8 KXL43354.1 - 0.034 14.0 0.6 0.041 13.7 0.6 1.1 1 0 0 1 1 1 0 Nucleolar protein 19 Spore_Cse60 PF10957.8 KXL43354.1 - 0.045 13.8 0.3 0.077 13.0 0.3 1.3 1 0 0 1 1 1 0 Sporulation protein Cse60 PPTA PF01239.22 KXL43355.1 - 8.4e-40 133.4 12.9 5.7e-08 32.2 0.0 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat WD40 PF00400.32 KXL43356.1 - 2.8e-07 31.1 5.7 0.00037 21.2 0.0 6.1 7 0 0 7 7 7 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL43356.1 - 9.2e-05 22.7 0.0 0.1 12.9 0.0 4.2 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DUF2457 PF10446.9 KXL43356.1 - 0.52 9.4 2.0 0.8 8.8 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) ATE_C PF04377.15 KXL43357.1 - 2e-48 164.4 0.7 4.2e-48 163.4 0.7 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KXL43357.1 - 4.9e-15 55.7 0.1 1.7e-14 54.0 0.0 2.0 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus Phage_CII PF05269.11 KXL43357.1 - 0.13 12.5 0.0 0.63 10.3 0.0 2.0 2 0 0 2 2 2 0 Bacteriophage CII protein DUF3328 PF11807.8 KXL43358.1 - 4.5e-24 85.4 1.2 1.5e-23 83.8 1.2 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Fungal_trans_2 PF11951.8 KXL43359.1 - 1.4e-11 43.8 0.1 1.8e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL43359.1 - 5.7e-07 29.5 10.4 1.1e-06 28.7 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1796 PF08795.10 KXL43359.1 - 0.077 13.0 0.7 0.2 11.6 0.7 1.7 1 1 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) FA_desaturase PF00487.24 KXL43361.1 - 3.9e-19 69.5 12.4 3.9e-19 69.5 12.4 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KXL43361.1 - 3e-16 59.3 0.2 7.9e-16 58.0 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DUF1189 PF06691.11 KXL43361.1 - 0.11 12.0 0.1 0.11 12.0 0.1 1.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1189) ADH_zinc_N PF00107.26 KXL43363.1 - 2.3e-10 40.6 0.6 3.6e-10 39.9 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXL43363.1 - 2.6e-10 40.2 1.0 4.3e-09 36.2 0.1 2.6 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KXL43363.1 - 0.0063 16.4 0.0 0.034 14.0 0.0 2.1 3 0 0 3 3 3 1 N-terminal domain of oxidoreductase Fungal_trans PF04082.18 KXL43364.1 - 1.3e-14 53.8 0.1 2.5e-14 53.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KXL43364.1 - 1.9e-06 28.0 10.5 5.1e-05 23.5 3.5 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXL43364.1 - 0.0011 19.6 16.9 0.033 15.0 5.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 KXL43364.1 - 0.0017 18.6 5.3 0.0034 17.6 5.3 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 KXL43364.1 - 0.061 13.8 16.8 0.17 12.4 7.0 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KXL43364.1 - 0.21 11.9 6.9 0.3 11.4 1.2 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXL43364.1 - 9.1 6.8 7.1 7.9 7.0 0.9 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type OsmC PF02566.19 KXL43365.1 - 4.7e-13 49.5 0.0 1.1e-12 48.3 0.0 1.5 2 0 0 2 2 2 1 OsmC-like protein Dak2 PF02734.17 KXL43366.1 - 7.9e-45 152.9 0.6 3.3e-44 150.8 0.4 2.2 2 0 0 2 2 2 1 DAK2 domain Hydrolase PF00702.26 KXL43366.1 - 0.075 13.3 0.1 0.63 10.3 0.1 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase RTA1 PF04479.13 KXL43367.1 - 1.5e-64 217.4 6.4 1.5e-64 217.4 6.4 1.4 2 0 0 2 2 2 1 RTA1 like protein NAD_binding_2 PF03446.15 KXL43368.1 - 9e-36 123.4 0.0 1.9e-35 122.4 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXL43368.1 - 1e-33 116.2 3.1 1.9e-23 83.0 0.9 2.5 2 1 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 KXL43368.1 - 0.00013 21.3 0.0 0.00032 20.1 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KXL43368.1 - 0.0019 18.7 0.1 0.0055 17.3 0.1 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KXL43368.1 - 0.0046 16.9 0.1 0.01 15.7 0.1 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KXL43368.1 - 0.065 12.8 0.0 3.2 7.3 0.3 2.9 2 1 1 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 KXL43368.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh PF00984.19 KXL43368.1 - 0.11 12.7 0.2 0.71 10.1 0.1 2.4 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain Transketolase_N PF00456.21 KXL43369.1 - 2.7e-127 424.3 0.0 5.1e-127 423.4 0.0 1.4 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KXL43369.1 - 1.2e-34 119.5 1.3 1.3e-34 119.4 0.0 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KXL43369.1 - 2.9e-07 30.4 0.0 7.2e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.20 KXL43369.1 - 2.2e-06 26.9 0.1 3.6e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KXL43369.1 - 3.5e-05 23.2 0.0 0.0001 21.6 0.0 1.8 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase adh_short_C2 PF13561.6 KXL43370.1 - 1.8e-47 161.9 0.4 2.5e-47 161.4 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL43370.1 - 6.8e-37 126.8 1.1 8.8e-37 126.5 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL43370.1 - 4.1e-09 36.6 0.4 6.8e-09 35.9 0.4 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KXL43370.1 - 0.0053 15.8 0.0 0.039 12.9 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXL43370.1 - 0.008 15.7 0.1 0.046 13.2 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Fungal_trans_2 PF11951.8 KXL43371.1 - 5.6e-10 38.6 7.4 1.5e-09 37.1 7.4 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL43371.1 - 2.5e-05 24.3 13.4 5e-05 23.3 13.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MIT PF04212.18 KXL43371.1 - 0.087 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Dickkopf_N PF04706.12 KXL43371.1 - 6.7 7.3 13.3 0.75 10.3 8.3 2.0 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region DASH_Dad3 PF08656.10 KXL43372.1 - 0.05 13.7 0.1 0.21 11.7 0.1 2.1 1 0 0 1 1 1 0 DASH complex subunit Dad3 OmpH PF03938.14 KXL43372.1 - 0.07 13.5 0.1 0.21 11.9 0.0 1.8 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) NAGLU_C PF12972.7 KXL43372.1 - 0.1 12.1 0.7 0.44 10.0 0.1 2.0 2 0 0 2 2 2 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain DUF615 PF04751.14 KXL43372.1 - 0.21 11.6 4.8 0.27 11.2 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF615) HAUS-augmin3 PF14932.6 KXL43372.1 - 0.55 9.8 4.2 2.9 7.4 0.0 2.9 2 1 0 3 3 3 0 HAUS augmin-like complex subunit 3 DUF4407 PF14362.6 KXL43372.1 - 1.9 7.8 10.5 2.9 7.2 4.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) APG17 PF04108.12 KXL43372.1 - 2.6 7.0 6.4 4.3 6.3 0.2 2.3 1 1 1 2 2 2 0 Autophagy protein Apg17 DivIC PF04977.15 KXL43372.1 - 3.7 7.4 5.1 7.4 6.4 1.3 2.7 2 1 0 2 2 2 0 Septum formation initiator TIM21 PF08294.11 KXL43373.1 - 3.7e-24 85.3 0.0 4.7e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 KXL43373.1 - 0.0001 22.0 0.0 0.00027 20.7 0.0 1.7 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 TPR_9 PF13371.6 KXL43374.1 - 1.6 9.0 6.2 7.4 6.8 0.2 3.2 1 1 1 3 3 3 0 Tetratricopeptide repeat Glyoxalase PF00903.25 KXL43375.1 - 5.8e-26 91.2 0.4 3.8e-18 65.9 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KXL43375.1 - 1.9e-13 50.7 0.2 1.7e-05 25.0 0.3 2.5 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KXL43375.1 - 7e-07 29.5 0.3 0.11 12.6 0.2 4.1 3 2 0 4 4 4 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 KXL43375.1 - 0.00021 21.5 0.1 0.0068 16.6 0.1 2.4 1 1 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal SR-25 PF10500.9 KXL43376.1 - 4.7 6.7 24.1 0.15 11.7 12.2 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF1761 PF08570.10 KXL43379.1 - 2.5e-28 98.9 4.0 2.8e-28 98.7 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) PRK PF00485.18 KXL43380.1 - 4.6e-07 29.8 0.0 7.7e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 KXL43380.1 - 2.1e-06 27.1 0.0 3.4e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.6 KXL43380.1 - 7e-05 23.4 0.1 0.00075 20.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KXL43380.1 - 0.0006 20.3 0.1 0.025 15.0 0.1 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KXL43380.1 - 0.00096 18.5 0.1 0.002 17.4 0.0 1.5 2 0 0 2 2 2 1 Zeta toxin T2SSE PF00437.20 KXL43380.1 - 0.0014 17.7 0.0 0.006 15.7 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_33 PF13671.6 KXL43380.1 - 0.0019 18.3 0.0 0.024 14.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXL43380.1 - 0.004 17.4 0.0 0.0097 16.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXL43380.1 - 0.0066 16.9 0.0 0.0099 16.3 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KXL43380.1 - 0.0093 15.9 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain NTPase_1 PF03266.15 KXL43380.1 - 0.0094 15.9 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 NTPase SRP54 PF00448.22 KXL43380.1 - 0.028 14.0 0.0 0.08 12.6 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RuvB_N PF05496.12 KXL43380.1 - 0.031 14.0 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 KXL43380.1 - 0.044 14.2 0.0 0.071 13.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 KXL43380.1 - 0.056 12.4 0.0 0.09 11.7 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KXL43380.1 - 0.058 13.1 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KXL43380.1 - 0.066 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_24 PF13479.6 KXL43380.1 - 0.071 12.8 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 KXL43380.1 - 0.073 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF2075 PF09848.9 KXL43380.1 - 0.081 12.1 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 KXL43380.1 - 0.085 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Thymidylate_kin PF02223.17 KXL43380.1 - 0.15 11.7 0.0 0.57 9.8 0.0 1.8 2 0 0 2 2 2 0 Thymidylate kinase GFA PF04828.14 KXL43381.1 - 0.0018 18.5 0.2 0.0018 18.5 0.2 1.8 2 1 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Cytochrome_CBB3 PF13442.6 KXL43381.1 - 0.042 14.2 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III Acetyltransf_3 PF13302.7 KXL43382.1 - 0.00016 22.3 0.0 0.00024 21.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Hepsin-SRCR PF09272.10 KXL43382.1 - 0.073 13.6 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Hepsin, SRCR domain IF-2B PF01008.17 KXL43383.1 - 7.5e-56 189.4 2.8 7.1e-31 107.4 0.0 2.7 2 1 0 2 2 2 2 Initiation factor 2 subunit family NIF PF03031.18 KXL43384.1 - 3.3e-55 186.1 0.0 4.6e-55 185.7 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Presenilin PF01080.17 KXL43384.1 - 0.64 8.7 1.3 0.8 8.4 1.3 1.2 1 0 0 1 1 1 0 Presenilin Alg14 PF08660.11 KXL43385.1 - 3.3e-45 154.2 0.0 8.5e-45 152.8 0.0 1.6 1 1 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like HCV_NS5a_1b PF08301.13 KXL43385.1 - 0.011 16.3 0.0 0.019 15.5 0.0 1.3 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a domain 1b Ima1_N PF09779.9 KXL43386.1 - 1.6e-31 110.0 2.1 3.9e-31 108.7 2.1 1.7 1 0 0 1 1 1 1 Ima1 N-terminal domain TPPK_C PF12555.8 KXL43386.1 - 0.0041 17.1 0.1 0.013 15.5 0.1 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphokinase C terminal zinc_ribbon_10 PF10058.9 KXL43386.1 - 1 9.1 2.8 35 4.2 0.0 2.6 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF2798 PF11391.8 KXL43386.1 - 3.2 7.9 6.7 0.71 9.9 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2798) Lar_restr_allev PF14354.6 KXL43386.1 - 3.8 8.0 4.8 0.9 10.0 1.1 1.9 2 1 0 2 2 2 0 Restriction alleviation protein Lar Glyco_transf_22 PF03901.17 KXL43387.1 - 7.5e-82 275.8 19.6 9.2e-82 275.5 19.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF5383 PF17355.2 KXL43387.1 - 0.24 11.7 0.1 24 5.3 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5383) UbiA PF01040.18 KXL43388.1 - 2.6e-44 151.4 17.7 3.4e-44 151.0 17.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF2079 PF09852.9 KXL43388.1 - 2.1 7.1 13.5 0.38 9.6 1.6 2.5 2 1 1 3 3 3 0 Predicted membrane protein (DUF2079) HIGH_NTase1_ass PF16581.5 KXL43389.1 - 0.047 13.7 0.0 0.076 13.0 0.0 1.3 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Citrate_ly_lig PF08218.11 KXL43389.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Citrate lyase ligase C-terminal domain CTP_transf_like PF01467.26 KXL43389.1 - 0.19 11.9 0.0 1.8 8.7 0.0 2.3 1 1 0 1 1 1 0 Cytidylyltransferase-like Selenoprotein_S PF06936.11 KXL43390.1 - 2.4 7.9 6.9 3.9 7.2 6.9 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) PP2C PF00481.21 KXL43391.1 - 3e-42 145.0 0.0 6.9e-42 143.9 0.0 1.5 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 KXL43391.1 - 0.0025 17.5 0.1 0.0048 16.6 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KXL43391.1 - 0.0039 17.1 0.1 1 9.2 0.0 3.2 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) DUF2892 PF11127.8 KXL43392.1 - 4.2 7.5 6.8 12 6.0 2.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2892) PNK3P PF08645.11 KXL43394.1 - 6.8e-57 191.7 0.0 1.2e-56 190.9 0.0 1.4 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 KXL43394.1 - 7.9e-26 90.9 0.0 2.9e-12 47.0 0.0 2.7 2 1 1 3 3 3 2 AAA domain KTI12 PF08433.10 KXL43394.1 - 4.6e-06 26.3 0.1 0.0026 17.2 0.0 2.3 2 0 0 2 2 2 2 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 KXL43394.1 - 7.1e-05 22.2 0.0 0.011 15.1 0.0 2.3 1 1 1 2 2 2 2 Zeta toxin SUR7 PF06687.12 KXL43396.1 - 1e-42 146.2 21.6 1.4e-42 145.8 21.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family RCR PF12273.8 KXL43396.1 - 0.086 13.5 0.4 0.086 13.5 0.4 3.2 3 0 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red CrgA PF06781.12 KXL43396.1 - 0.24 11.5 0.0 0.24 11.5 0.0 3.3 2 1 1 3 3 3 0 Cell division protein CrgA ILVD_EDD PF00920.21 KXL43398.1 - 1.1e-152 509.3 0.0 1.3e-152 509.1 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family HET PF06985.11 KXL43399.1 - 5e-10 39.9 1.0 1.1e-06 29.1 0.0 2.8 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) MmgE_PrpD PF03972.14 KXL43400.1 - 1.6e-122 409.2 3.2 2e-122 408.9 3.2 1.0 1 0 0 1 1 1 1 MmgE/PrpD family HHH PF00633.23 KXL43401.1 - 0.014 15.2 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif PIN_11 PF18479.1 KXL43401.1 - 0.093 12.9 0.1 0.13 12.5 0.1 1.3 1 0 0 1 1 1 0 PIN like domain Nucleolin_bd PF16725.5 KXL43401.1 - 0.21 11.3 1.6 2.5 7.8 0.1 2.3 1 1 1 2 2 2 0 Nucleolin binding domain adh_short_C2 PF13561.6 KXL43404.1 - 4.2e-58 196.7 2.9 4.8e-58 196.5 2.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL43404.1 - 1.3e-51 174.9 2.9 1.7e-51 174.5 2.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL43404.1 - 1.4e-11 44.7 0.3 2.4e-11 43.9 0.3 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL43404.1 - 2.4e-05 23.9 0.0 5.2e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXL43404.1 - 0.00017 20.8 0.1 0.00027 20.2 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KXL43404.1 - 0.00046 19.3 0.2 0.00072 18.6 0.2 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.18 KXL43404.1 - 0.0012 18.8 0.7 0.0016 18.3 0.0 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 KXL43404.1 - 0.0013 18.2 0.1 0.0024 17.3 0.0 1.4 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Methyltransf_12 PF08242.12 KXL43404.1 - 0.0017 19.0 0.0 0.0027 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.15 KXL43404.1 - 0.0025 17.0 0.0 0.0032 16.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein TrkA_N PF02254.18 KXL43404.1 - 0.0034 17.6 0.1 0.0077 16.5 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain NmrA PF05368.13 KXL43404.1 - 0.02 14.5 0.2 0.043 13.4 0.1 1.6 2 0 0 2 2 2 0 NmrA-like family F420_oxidored PF03807.17 KXL43404.1 - 0.08 13.5 0.0 0.37 11.4 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AAA PF00004.29 KXL43405.1 - 5.3e-17 62.5 0.0 9e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXL43405.1 - 0.079 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXL43405.1 - 0.18 12.2 0.4 0.43 11.0 0.0 1.8 2 0 0 2 2 2 0 RNA helicase ADH_zinc_N PF00107.26 KXL43406.1 - 2.3e-21 76.1 0.5 5e-21 75.0 0.5 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXL43406.1 - 3e-11 44.5 0.1 6.7e-11 43.4 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXL43406.1 - 0.006 16.5 0.0 0.019 14.9 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KXL43406.1 - 0.021 14.3 2.1 0.038 13.4 2.1 1.5 1 1 0 1 1 1 0 short chain dehydrogenase LDcluster4 PF18306.1 KXL43406.1 - 0.025 14.2 1.5 0.036 13.6 1.5 1.3 1 0 0 1 1 1 0 SLOG cluster4 family Glu_synthase PF01645.17 KXL43406.1 - 0.026 13.7 0.2 0.045 12.9 0.2 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase SIS_2 PF13580.6 KXL43406.1 - 0.068 13.2 0.3 0.13 12.2 0.3 1.5 1 0 0 1 1 1 0 SIS domain tRNA-synt_1b PF00579.25 KXL43407.1 - 6.2e-72 242.4 0.0 8.2e-72 242.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 KXL43407.1 - 4.3e-37 126.6 0.0 1.1e-36 125.3 0.0 1.7 1 1 1 2 2 2 1 Tyrosyl-tRNA synthetase C-terminal domain Complex1_LYR PF05347.15 KXL43408.1 - 6.3e-15 55.0 0.1 1.1e-14 54.2 0.1 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KXL43408.1 - 1.6e-06 28.7 0.1 2.7e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Arg_decarb_HB PF17810.1 KXL43408.1 - 0.055 13.7 0.2 0.18 12.1 0.0 1.9 3 0 0 3 3 3 0 Arginine decarboxylase helical bundle domain LolA_like PF17131.4 KXL43408.1 - 0.1 12.3 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein-sorting protein Acetyltransf_1 PF00583.25 KXL43409.1 - 4.4e-11 43.0 0.0 5.6e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 KXL43409.1 - 0.0005 20.2 0.0 0.0015 18.7 0.0 1.7 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 KXL43409.1 - 0.00062 19.7 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXL43409.1 - 0.003 17.9 0.0 0.0045 17.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXL43409.1 - 0.0037 17.2 0.0 0.0068 16.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein TAF1D PF15333.6 KXL43409.1 - 0.011 15.5 2.1 0.015 15.0 2.1 1.4 1 1 0 1 1 1 0 TATA box-binding protein-associated factor 1D Pescadillo_N PF06732.11 KXL43410.1 - 3.7e-123 410.4 0.1 3.7e-123 410.4 0.1 1.6 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 KXL43410.1 - 0.00018 21.9 0.1 0.0014 19.0 0.1 2.3 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain DUF2457 PF10446.9 KXL43410.1 - 1.3 8.1 30.4 2.6 7.1 30.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PIG-U PF06728.13 KXL43411.1 - 7.4e-108 361.0 31.1 8.6e-108 360.8 31.1 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Pyr_redox_3 PF13738.6 KXL43413.1 - 3.6e-17 62.6 0.1 3.3e-14 52.8 0.1 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXL43413.1 - 1.6e-16 59.9 1.1 1.1e-14 53.8 0.6 2.6 3 1 0 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXL43413.1 - 3.7e-15 55.9 0.0 9.5e-10 38.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXL43413.1 - 1.1e-11 44.5 0.9 1.8e-08 33.9 0.3 3.1 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXL43413.1 - 1.1e-08 35.2 0.2 0.0065 16.5 0.0 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.24 KXL43413.1 - 2.8e-08 33.8 0.7 7.1e-06 25.8 0.7 3.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXL43413.1 - 5.3e-07 29.8 0.0 1.2e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXL43413.1 - 5.8e-05 22.0 0.7 0.021 13.5 0.0 3.6 4 0 0 4 4 4 1 HI0933-like protein Mqo PF06039.15 KXL43413.1 - 0.00056 18.6 0.2 0.35 9.4 0.0 2.4 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) GIDA PF01134.22 KXL43413.1 - 0.00058 19.0 0.1 0.13 11.3 0.0 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 KXL43413.1 - 0.0032 16.7 0.2 0.2 10.9 0.1 2.6 3 0 0 3 3 3 1 Thi4 family Pyr_redox PF00070.27 KXL43413.1 - 0.01 16.4 0.2 4.4 7.9 0.1 3.6 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXL43413.1 - 0.045 13.1 1.8 0.066 12.5 0.1 2.0 2 1 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXL43413.1 - 0.054 12.7 0.1 0.14 11.4 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Mur_ligase_M PF08245.12 KXL43414.1 - 5.6e-06 26.5 0.2 3.7e-05 23.8 0.2 2.2 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_M PF08245.12 KXL43415.1 - 1.1e-05 25.6 0.1 0.48 10.4 0.0 3.7 3 1 0 3 3 3 2 Mur ligase middle domain Mur_ligase_C PF02875.21 KXL43415.1 - 0.073 13.3 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain DUF2322 PF10084.9 KXL43415.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2322) DUF3939 PF13075.6 KXL43415.1 - 0.15 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3939) MutS_V PF00488.21 KXL43416.1 - 3.2e-69 232.7 0.4 6.5e-69 231.7 0.4 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXL43416.1 - 3.4e-39 135.1 0.0 6.3e-39 134.2 0.0 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KXL43416.1 - 3e-32 111.2 0.0 1.1e-31 109.4 0.0 1.9 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.18 KXL43416.1 - 1.2e-15 57.6 0.1 2.4e-15 56.6 0.1 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 KXL43416.1 - 4.1e-12 46.5 0.0 1e-11 45.3 0.0 1.7 1 0 0 1 1 1 1 MutS domain II AAA_29 PF13555.6 KXL43416.1 - 0.13 12.0 0.1 0.32 10.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KXL43416.1 - 0.22 12.0 3.4 0.13 12.7 0.3 2.1 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 KXL43417.1 - 8.8e-45 152.6 0.0 1.5e-44 151.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 KXL43417.1 - 2.8e-16 59.6 3.6 5.3e-16 58.7 3.6 1.4 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.23 KXL43417.1 - 5.9e-06 26.3 0.0 0.00054 20.0 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.17 KXL43417.1 - 0.0011 19.3 0.0 0.0025 18.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KXL43417.1 - 0.049 14.0 0.0 0.16 12.4 0.0 2.0 1 0 0 1 1 1 0 Elongation factor Tu domain 2 Roc PF08477.13 KXL43417.1 - 0.082 13.1 0.0 7.6 6.8 0.0 2.4 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Di19_C PF14571.6 KXL43417.1 - 0.1 13.2 0.2 0.25 11.9 0.2 1.6 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal FeoB_N PF02421.18 KXL43417.1 - 0.13 11.8 0.1 2.3 7.7 0.2 2.6 2 1 0 2 2 2 0 Ferrous iron transport protein B Glyco_hydro_43 PF04616.14 KXL43420.1 - 2.5e-28 99.2 1.3 3.2e-28 98.9 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 RCC1 PF00415.18 KXL43421.1 - 1.5e-23 83.2 0.3 2.1e-07 31.5 0.0 4.9 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KXL43421.1 - 4.7e-12 46.1 0.0 4.1e-08 33.4 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain RCC1_2 PF13540.6 KXL43421.1 - 2.7e-09 36.6 2.1 8.3e-08 31.8 0.5 3.3 3 0 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.6 KXL43421.1 - 5e-07 30.1 0.8 3.4e-05 24.3 0.1 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXL43421.1 - 2.1e-06 28.2 0.1 5.2e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXL43421.1 - 0.00017 21.8 1.5 0.0094 16.3 0.6 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXL43421.1 - 0.013 15.9 0.4 6.8 7.6 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeat Mhr1 PF12829.7 KXL43421.1 - 0.2 11.8 0.4 5.7 7.1 0.0 2.6 2 0 0 2 2 2 0 Transcriptional regulation of mitochondrial recombination DUF4407 PF14362.6 KXL43421.1 - 2.4 7.4 4.9 0.64 9.3 1.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SIS PF01380.22 KXL43422.1 - 2.5e-09 37.1 0.1 8.8e-09 35.3 0.1 1.9 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.6 KXL43422.1 - 7.5e-07 29.3 0.0 0.00013 22.1 0.1 2.3 1 1 1 2 2 2 2 SIS domain ARID PF01388.21 KXL43424.1 - 1.3e-18 67.4 0.2 3.3e-18 66.1 0.2 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Flavokinase PF01687.17 KXL43427.1 - 1.2e-31 109.2 0.0 1.7e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Zn_clus PF00172.18 KXL43428.1 - 0.017 15.2 8.2 0.031 14.4 8.2 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 KXL43428.1 - 0.039 13.9 0.0 0.084 12.9 0.0 1.5 1 0 0 1 1 1 0 PAS fold Pal1 PF08316.11 KXL43429.1 - 2.6e-18 67.1 0.0 9.2e-18 65.3 0.0 1.9 1 1 0 1 1 1 1 Pal1 cell morphology protein DHHC PF01529.20 KXL43430.1 - 1.8e-27 96.1 2.5 1.8e-27 96.1 2.5 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase zf-CRD PF17979.1 KXL43430.1 - 0.0085 16.2 0.2 0.013 15.6 0.2 1.2 1 0 0 1 1 1 1 Cysteine rich domain with multizinc binding regions Ca_hom_mod PF14798.6 KXL43430.1 - 0.15 11.2 3.2 0.65 9.1 0.4 2.2 1 1 1 2 2 2 0 Calcium homeostasis modulator NAD_binding_10 PF13460.6 KXL43431.1 - 2.1e-06 27.8 0.0 3.2e-05 23.9 0.0 2.3 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXL43431.1 - 0.00027 20.1 0.0 0.00053 19.1 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXL43431.1 - 0.00039 20.0 0.0 0.00057 19.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KXL43431.1 - 0.0052 16.0 0.0 0.079 12.1 0.0 2.3 3 0 0 3 3 3 1 Male sterility protein RmlD_sub_bind PF04321.17 KXL43431.1 - 0.045 12.9 0.0 0.2 10.7 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain Arylsulfotran_2 PF14269.6 KXL43432.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Arylsulfotransferase (ASST) Glyco_transf_25 PF01755.17 KXL43433.1 - 0.086 12.7 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) F-box-like PF12937.7 KXL43434.1 - 0.014 15.3 0.0 0.049 13.5 0.0 2.0 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 KXL43434.1 - 0.12 12.3 1.0 0.24 11.3 0.3 1.9 2 0 0 2 2 2 0 F-box domain Ehrlichia_rpt PF09528.10 KXL43434.1 - 0.19 11.2 1.4 1.3 8.6 0.1 2.4 2 0 0 2 2 2 0 Ehrlichia tandem repeat (Ehrlichia_rpt) Peptidase_S8 PF00082.22 KXL43435.1 - 3.9e-07 29.6 0.1 6e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 Subtilase family Pro-kuma_activ PF09286.11 KXL43435.1 - 2.2e-05 24.8 0.0 3.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Ribosomal_S16 PF00886.19 KXL43436.1 - 6e-21 74.3 0.1 1.8e-20 72.7 0.1 1.8 1 1 0 1 1 1 1 Ribosomal protein S16 Septin PF00735.18 KXL43437.1 - 7.5e-108 360.1 0.0 1.6e-107 359.0 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KXL43437.1 - 2.6e-06 27.5 0.0 6e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KXL43437.1 - 0.00075 19.6 2.1 1.4 8.9 0.0 3.1 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 KXL43437.1 - 0.0066 16.0 0.2 0.26 10.8 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KXL43437.1 - 0.03 14.2 3.1 0.034 14.0 0.2 2.5 3 1 0 3 3 3 0 RsgA GTPase AAA_22 PF13401.6 KXL43437.1 - 0.078 13.2 0.6 0.2 11.9 0.1 2.0 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KXL43437.1 - 0.08 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KXL43437.1 - 0.72 10.3 4.5 8.2 6.9 3.8 2.3 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KXL43437.1 - 1.1 8.5 3.1 0.4 10.0 0.2 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family WD40 PF00400.32 KXL43438.1 - 1.4e-10 41.6 0.0 0.0019 19.0 0.0 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KXL43438.1 - 0.015 14.2 0.0 0.04 12.9 0.0 1.6 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KXL43438.1 - 0.048 14.0 0.0 6 7.2 0.0 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF2415 PF10313.9 KXL43438.1 - 0.15 12.0 0.0 1.2 9.1 0.0 2.4 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) Glyco_hydro_64 PF16483.5 KXL43440.1 - 4.2e-125 417.9 0.2 5.7e-125 417.4 0.2 1.2 1 0 0 1 1 1 1 Beta-1,3-glucanase Pro-kuma_activ PF09286.11 KXL43441.1 - 1e-22 81.0 0.0 1.2e-22 80.7 0.0 1.1 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain DUF485 PF04341.12 KXL43441.1 - 0.036 14.0 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF485 Homeobox_KN PF05920.11 KXL43442.1 - 5.3e-09 35.8 3.4 2.2e-08 33.9 3.4 2.1 1 1 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KXL43442.1 - 0.00012 21.9 1.3 0.00034 20.4 1.3 1.8 1 1 0 1 1 1 1 Homeodomain adh_short PF00106.25 KXL43445.1 - 1.6e-15 57.1 0.0 8.7e-15 54.7 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KXL43445.1 - 8.6e-09 35.5 0.0 1.3e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KXL43445.1 - 6.6e-05 22.6 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KXL43445.1 - 0.0022 17.5 0.0 0.0029 17.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXL43445.1 - 0.0093 15.1 0.0 0.023 13.9 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein ZapB PF06005.12 KXL43446.1 - 0.0087 16.5 4.3 0.062 13.7 0.0 2.8 3 1 0 3 3 3 1 Cell division protein ZapB UreD PF01774.17 KXL43446.1 - 0.015 15.2 4.3 1.6 8.6 0.8 2.2 1 1 1 2 2 2 0 UreD urease accessory protein Hepar_II_III PF07940.13 KXL43446.1 - 0.033 13.8 0.5 0.038 13.6 0.5 1.2 1 0 0 1 1 1 0 Heparinase II/III-like protein 5_nucleotid PF05761.14 KXL43446.1 - 0.29 10.0 0.1 0.37 9.6 0.1 1.1 1 0 0 1 1 1 0 5' nucleotidase family DUF4404 PF14357.6 KXL43446.1 - 1 10.1 4.6 1.4 9.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Aa_trans PF01490.18 KXL43447.1 - 2.3e-94 316.4 16.1 2.3e-94 316.4 16.1 1.3 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein ORMDL PF04061.14 KXL43447.1 - 0.34 10.7 0.0 0.34 10.7 0.0 2.5 3 0 0 3 3 3 0 ORMDL family EMP70 PF02990.16 KXL43447.1 - 2 7.0 8.5 0.59 8.7 4.5 2.0 2 1 0 2 2 2 0 Endomembrane protein 70 DUF1769 PF08588.10 KXL43448.1 - 4.5e-26 90.8 0.7 4.2e-25 87.7 0.4 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1769) GFA PF04828.14 KXL43449.1 - 1.2e-08 35.1 0.4 3.4e-08 33.7 0.4 1.7 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Ldl_recept_b PF00058.17 KXL43450.1 - 0.63 10.6 2.1 15 6.2 0.1 2.8 3 0 0 3 3 3 0 Low-density lipoprotein receptor repeat class B zf-C2HCIx2C PF10782.9 KXL43451.1 - 0.29 11.1 0.5 1.5 8.8 0.0 2.0 1 1 1 2 2 2 0 Zinc-finger Fib_alpha PF08702.10 KXL43451.1 - 0.59 10.3 4.8 3.5 7.8 0.8 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Nramp PF01566.18 KXL43453.1 - 4.7e-79 266.0 24.1 4.7e-79 266.0 24.1 2.4 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein COG5 PF10392.9 KXL43454.1 - 0.00043 20.5 0.3 0.00043 20.5 0.3 1.8 3 0 0 3 3 3 1 Golgi transport complex subunit 5 COG7 PF10191.9 KXL43454.1 - 0.0027 16.0 0.0 0.024 12.9 0.0 1.9 2 0 0 2 2 2 1 Golgi complex component 7 (COG7) DUF4226 PF10774.9 KXL43454.1 - 0.065 13.5 0.1 0.15 12.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) DASH_Spc19 PF08287.11 KXL43454.1 - 0.081 12.8 3.9 0.54 10.1 1.1 2.8 2 1 0 2 2 2 0 Spc19 bZIP_1 PF00170.21 KXL43454.1 - 0.13 12.3 2.9 12 6.1 0.5 3.2 3 0 0 3 3 3 0 bZIP transcription factor Apolipoprotein PF01442.18 KXL43454.1 - 0.59 10.0 4.4 0.39 10.6 0.2 2.4 2 2 0 2 2 2 0 Apolipoprotein A1/A4/E domain PARP PF00644.20 KXL43455.1 - 2.3e-08 33.9 0.1 4.4e-08 32.9 0.1 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 KXL43455.1 - 3.8e-06 26.6 0.0 8.3e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KXL43455.1 - 0.099 12.9 0.2 0.52 10.6 0.0 2.3 3 0 0 3 3 3 0 RWD domain Prok-E2_B PF14461.6 KXL43455.1 - 0.14 11.9 0.0 0.39 10.4 0.0 1.7 1 0 0 1 1 1 0 Prokaryotic E2 family B DNA_pol_phi PF04931.13 KXL43455.1 - 0.17 9.9 6.1 0.27 9.3 6.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi YTH PF04146.15 KXL43456.1 - 6e-30 104.4 0.0 1.5e-28 99.8 0.0 2.0 1 1 0 1 1 1 1 YT521-B-like domain DUF4174 PF13778.6 KXL43456.1 - 0.18 12.3 0.0 0.23 12.0 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4174) Sugar_tr PF00083.24 KXL43458.1 - 1.4e-93 314.2 26.6 1.8e-93 313.9 26.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL43458.1 - 1e-16 60.9 37.9 2.9e-13 49.5 12.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydr_30_2 PF14587.6 KXL43459.1 - 2.4e-37 129.4 0.4 3.8e-31 109.0 0.1 2.1 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 MFS_1 PF07690.16 KXL43460.1 - 4.2e-17 62.1 27.0 9.1e-17 61.0 22.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Colicin_K PF17500.2 KXL43460.1 - 1.7 9.3 4.3 27 5.4 0.1 3.4 1 1 2 3 3 3 0 Colicin-K zf-C2H2_10 PF16588.5 KXL43461.1 - 0.0026 17.5 2.4 0.0045 16.7 2.4 1.4 1 0 0 1 1 1 1 C2H2 zinc-finger zf-CCHC PF00098.23 KXL43461.1 - 0.012 15.7 4.1 0.023 14.7 4.1 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 KXL43461.1 - 0.014 15.2 4.7 0.023 14.5 4.7 1.3 1 0 0 1 1 1 0 Zinc knuckle PyrI_C PF02748.15 KXL43461.1 - 0.054 13.4 1.1 0.091 12.7 1.1 1.3 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF3172 PF11371.8 KXL43461.1 - 0.15 11.7 0.0 0.2 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3172) Sugar_tr PF00083.24 KXL43462.1 - 5e-80 269.6 23.5 5.7e-80 269.4 23.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL43462.1 - 4.2e-27 95.0 23.0 6.9e-27 94.3 23.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KXL43462.1 - 0.00019 20.1 1.4 0.00019 20.1 1.4 3.1 2 2 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.13 KXL43462.1 - 0.0012 17.3 2.8 0.0012 17.3 2.8 2.2 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) YMF19 PF02326.15 KXL43462.1 - 0.014 16.2 1.2 0.026 15.3 0.0 2.1 2 0 0 2 2 2 0 Plant ATP synthase F0 OATP PF03137.20 KXL43462.1 - 0.014 13.7 0.5 0.014 13.7 0.5 3.1 2 2 3 5 5 5 0 Organic Anion Transporter Polypeptide (OATP) family Melibiase_2 PF16499.5 KXL43463.1 - 6.5e-35 120.7 2.8 3.5e-23 82.2 0.4 3.4 1 1 2 3 3 3 3 Alpha galactosidase A Ricin_B_lectin PF00652.22 KXL43463.1 - 4.3e-13 49.6 2.8 8.1e-13 48.7 2.8 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Melibiase_C PF17801.1 KXL43463.1 - 9.1e-05 22.5 0.7 0.00045 20.3 0.7 2.2 1 1 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain NOT2_3_5 PF04153.18 KXL43464.1 - 8.4e-27 93.8 11.5 9.1e-27 93.7 11.5 1.0 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.9 KXL43464.1 - 0.0012 18.6 4.0 0.0012 18.6 4.0 1.8 1 1 1 2 2 2 1 Uncharacterised conserved protein (DUF2373) zf-C2H2 PF00096.26 KXL43465.1 - 0.00038 20.8 0.6 0.44 11.1 0.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXL43465.1 - 1.7 9.7 6.6 15 6.8 0.0 3.2 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KXL43465.1 - 4.8 7.0 8.0 11 5.9 1.4 2.4 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Proteasome PF00227.26 KXL43467.1 - 4e-46 156.9 0.0 5.5e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXL43467.1 - 3.3e-12 45.9 0.2 5.9e-12 45.0 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF2373 PF10180.9 KXL43468.1 - 1.3e-22 79.4 0.1 2.9e-22 78.3 0.1 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) DUF678 PF05077.12 KXL43468.1 - 1.2 9.3 4.0 3.4 7.9 1.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF678) Pkinase PF00069.25 KXL43469.1 - 2.1e-65 220.7 0.0 2.8e-65 220.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL43469.1 - 4.7e-38 130.9 0.0 7.2e-38 130.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXL43469.1 - 1.4e-05 24.1 0.0 2.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXL43469.1 - 0.0027 17.1 0.0 0.0043 16.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXL43469.1 - 0.045 13.7 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KXL43469.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 SH2_2 PF14633.6 KXL43470.1 - 2e-81 272.5 0.0 2e-81 272.5 0.0 2.1 2 0 0 2 2 2 1 SH2 domain HHH_7 PF14635.6 KXL43470.1 - 1.5e-34 118.5 0.0 2.7e-34 117.6 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 KXL43470.1 - 1.9e-31 108.9 0.0 7.1e-31 107.0 0.0 2.1 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.6 KXL43470.1 - 4.4e-28 98.0 1.7 1.3e-27 96.5 1.7 1.8 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 KXL43470.1 - 9.1e-17 61.4 34.5 9.1e-17 61.4 34.5 5.4 5 0 0 5 5 5 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 KXL43470.1 - 2.9e-07 31.3 3.5 1.1e-05 26.2 3.5 3.5 1 1 0 1 1 1 1 HHH domain SH2 PF00017.24 KXL43470.1 - 0.0015 18.6 0.0 0.0042 17.2 0.0 1.8 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.7 KXL43470.1 - 0.056 13.7 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif Tex_YqgF PF16921.5 KXL43470.1 - 0.067 13.7 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 Tex protein YqgF-like domain PSD4 PF07631.11 KXL43470.1 - 0.37 11.3 4.8 13 6.3 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1592) ADH_N PF08240.12 KXL43471.1 - 2.3e-22 78.9 0.4 4.7e-22 77.9 0.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXL43471.1 - 1.4e-15 57.4 0.0 2.5e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KXL43471.1 - 8.6e-06 25.2 0.2 1.4e-05 24.6 0.2 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KXL43471.1 - 0.015 14.6 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KXL43471.1 - 0.16 11.8 0.1 0.25 11.2 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2207 PF09972.9 KXL43472.1 - 8.7 5.0 12.7 10 4.7 12.7 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Collagen PF01391.18 KXL43473.1 - 0.0026 17.5 2.0 0.0057 16.4 2.0 1.6 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Methyltransf_2 PF00891.18 KXL43474.1 - 8.3e-14 51.4 0.0 1.4e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 KXL43474.1 - 0.0018 18.2 0.0 0.0041 17.1 0.0 1.6 1 0 0 1 1 1 1 Dimerisation domain Kelch_6 PF13964.6 KXL43475.1 - 0.079 13.3 1.9 0.32 11.3 1.9 2.1 1 0 0 1 1 1 0 Kelch motif Cyto_heme_lyase PF01265.17 KXL43477.1 - 7.3e-39 134.1 5.2 1.2e-34 120.3 1.3 3.0 1 1 1 2 2 2 2 Cytochrome c/c1 heme lyase MDD_C PF18376.1 KXL43478.1 - 1.5e-64 217.2 0.1 2e-64 216.8 0.1 1.1 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 KXL43478.1 - 3.9e-09 36.6 1.1 1e-08 35.3 1.1 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain DUF1819 PF08849.11 KXL43478.1 - 0.11 12.3 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) Lactamase_B PF00753.27 KXL43479.1 - 2.3e-17 63.7 0.2 4.5e-17 62.7 0.2 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXL43479.1 - 0.0013 18.2 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Sulf_transp PF04143.14 KXL43480.1 - 5.1e-34 118.2 24.5 7.5e-33 114.4 24.5 2.0 1 1 0 1 1 1 1 Sulphur transport DUF1275 PF06912.11 KXL43481.1 - 8.4e-41 140.0 16.9 1e-40 139.8 16.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) rRNA_proc-arch PF13234.6 KXL43483.1 - 8.1e-84 281.7 0.0 1.5e-83 280.9 0.0 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 KXL43483.1 - 4.1e-55 185.9 2.1 1.1e-54 184.5 2.1 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 KXL43483.1 - 1e-18 67.7 0.0 2.8e-18 66.3 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXL43483.1 - 3.1e-07 30.7 0.0 1.4e-06 28.6 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL43483.1 - 3.1e-06 27.3 0.0 8.2e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 KXL43483.1 - 0.016 14.3 0.0 0.072 12.1 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein ATPase_2 PF01637.18 KXL43483.1 - 0.028 14.3 0.0 0.11 12.3 0.0 2.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF5388 PF17363.2 KXL43483.1 - 0.049 13.8 0.3 0.34 11.1 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5388) AXIN1_TNKS_BD PF16646.5 KXL43483.1 - 0.11 13.4 0.1 0.11 13.4 0.1 2.4 2 0 0 2 2 2 0 Axin-1 tankyrase binding domain zf-C2H2_8 PF15909.5 KXL43484.1 - 0.063 13.6 0.0 3.2 8.1 0.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc ribbon PPR_2 PF13041.6 KXL43485.1 - 3.2e-12 46.4 0.0 0.032 14.4 0.0 4.7 3 1 1 4 4 4 4 PPR repeat family PPR PF01535.20 KXL43485.1 - 0.001 19.2 1.8 0.27 11.6 0.0 4.8 5 0 0 5 5 5 1 PPR repeat PPR_3 PF13812.6 KXL43485.1 - 0.0025 17.8 0.0 36 4.5 0.0 3.8 3 1 1 4 4 4 0 Pentatricopeptide repeat domain Sec3-PIP2_bind PF15277.6 KXL43485.1 - 0.0086 16.2 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH PPR_1 PF12854.7 KXL43485.1 - 0.098 12.4 0.0 37 4.1 0.0 3.5 3 0 0 3 3 3 0 PPR repeat MRP-S25 PF13741.6 KXL43486.1 - 4e-49 167.2 6.4 2.5e-41 141.7 1.2 2.3 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 KXL43486.1 - 0.12 12.6 2.6 0.22 11.8 0.4 2.3 2 1 1 3 3 3 0 Mitochondrial ribosomal protein S23 GRAB PF10375.9 KXL43487.1 - 1.2e-09 37.6 0.1 3e-09 36.4 0.1 1.7 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Golgin_A5 PF09787.9 KXL43487.1 - 0.0017 17.9 52.8 0.16 11.4 15.1 3.4 1 1 2 3 3 3 3 Golgin subfamily A member 5 CENP-F_leu_zip PF10473.9 KXL43487.1 - 0.0031 17.6 54.8 0.028 14.5 22.7 3.3 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 KXL43487.1 - 0.006 16.2 45.3 0.019 14.6 13.3 3.0 1 1 2 3 3 3 1 Intermediate filament protein MAD PF05557.13 KXL43487.1 - 0.14 10.5 49.5 0.31 9.3 22.8 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein BST2 PF16716.5 KXL43487.1 - 0.45 11.1 35.8 0.08 13.5 6.5 5.2 2 2 2 4 4 4 0 Bone marrow stromal antigen 2 DUF4407 PF14362.6 KXL43487.1 - 0.6 9.4 41.2 0.71 9.2 9.2 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 KXL43487.1 - 1 8.2 49.4 1.4 7.8 16.7 3.4 1 1 3 4 4 4 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KXL43487.1 - 1.1 9.4 54.9 0.64 10.1 14.6 4.5 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 KXL43487.1 - 2.4 8.2 24.6 1.3 9.0 5.4 3.6 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) IFT57 PF10498.9 KXL43487.1 - 2.9 6.8 38.6 2.7 6.9 8.0 3.1 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 Rootletin PF15035.6 KXL43487.1 - 3.2 7.7 53.7 33 4.4 18.2 3.6 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion ADIP PF11559.8 KXL43487.1 - 3.4 7.7 51.6 5.7 7.0 8.9 4.4 2 2 2 4 4 4 0 Afadin- and alpha -actinin-Binding Tweety PF04906.13 KXL43487.1 - 7.1 5.2 11.0 2.6 6.6 3.5 2.4 2 0 0 2 2 2 0 Tweety Fib_alpha PF08702.10 KXL43487.1 - 7.9 6.7 28.6 9.3 6.4 3.6 3.6 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.8 KXL43487.1 - 8.6 3.7 48.6 21 2.4 9.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) NPV_P10 PF05531.12 KXL43487.1 - 8.8 6.9 14.1 2.6 8.6 1.1 4.1 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein F_actin_bind PF08919.10 KXL43487.1 - 9.9 6.3 13.9 30 4.8 4.3 3.5 2 2 0 2 2 2 0 F-actin binding Adeno_E1B_55K_N PF04623.12 KXL43489.1 - 0.1 13.3 0.1 0.33 11.7 0.1 1.8 1 0 0 1 1 1 0 Adenovirus E1B protein N-terminus SUZ PF12752.7 KXL43489.1 - 0.74 10.6 4.0 1.5 9.6 4.0 1.5 1 0 0 1 1 1 0 SUZ domain APH PF01636.23 KXL43490.1 - 0.0016 18.4 0.1 0.0022 18.0 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family AAA_21 PF13304.6 KXL43492.1 - 7.1e-05 22.8 0.1 0.0001 22.3 0.1 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 KXL43492.1 - 0.0024 18.4 0.0 0.0035 17.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter IPPT PF01715.17 KXL43493.1 - 2e-64 217.5 0.1 2.8e-64 217.1 0.1 1.1 1 0 0 1 1 1 1 IPP transferase AAA_33 PF13671.6 KXL43493.1 - 5.7e-05 23.3 0.8 0.0037 17.4 0.0 3.1 3 1 0 3 3 3 1 AAA domain IPT PF01745.16 KXL43493.1 - 7.1e-05 22.3 0.0 0.00015 21.2 0.0 1.6 1 0 0 1 1 1 1 Isopentenyl transferase zf-met PF12874.7 KXL43493.1 - 0.00083 19.7 6.0 0.0023 18.2 6.0 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KXL43493.1 - 0.0025 18.1 0.4 0.0048 17.2 0.4 1.4 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) AAA_18 PF13238.6 KXL43493.1 - 0.0043 17.6 0.2 0.037 14.6 0.0 2.6 3 0 0 3 3 3 1 AAA domain zf-C2H2_jaz PF12171.8 KXL43493.1 - 0.006 16.8 7.1 0.006 16.8 7.1 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding AAA_16 PF13191.6 KXL43493.1 - 0.0069 16.8 0.4 0.034 14.5 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain OrsD PF12013.8 KXL43493.1 - 0.036 14.5 0.8 0.074 13.5 0.8 1.5 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D AAA_22 PF13401.6 KXL43493.1 - 0.047 14.0 0.6 0.28 11.4 0.1 2.5 3 1 0 3 3 3 0 AAA domain AAA_25 PF13481.6 KXL43493.1 - 0.063 12.9 0.0 0.21 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KXL43493.1 - 0.072 13.5 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Cytidylate_kin PF02224.18 KXL43493.1 - 0.073 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase AAA_5 PF07728.14 KXL43493.1 - 0.077 13.0 0.0 0.25 11.3 0.1 1.8 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 KXL43493.1 - 0.11 12.6 0.3 0.54 10.3 0.1 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain AAA PF00004.29 KXL43493.1 - 0.13 12.7 0.0 0.48 10.9 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Abhydrolase_1 PF00561.20 KXL43494.1 - 1.2e-11 44.8 0.0 1.5e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXL43494.1 - 1.7e-08 35.4 1.8 3.7e-08 34.2 1.8 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF5399 PF17377.2 KXL43494.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5399) PalH PF08733.10 KXL43495.1 - 7e-117 390.1 0.1 8.6e-117 389.8 0.1 1.1 1 0 0 1 1 1 1 PalH/RIM21 CRCB PF02537.15 KXL43496.1 - 1.8e-34 117.9 7.0 1.2e-19 70.5 9.1 2.7 2 1 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) 5TM-5TMR_LYT PF07694.12 KXL43496.1 - 4.1 6.9 15.4 0.071 12.6 2.3 3.4 3 1 0 4 4 4 0 5TMR of 5TMR-LYT UPRTase PF14681.6 KXL43497.1 - 2e-73 246.2 0.0 2.3e-73 246.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KXL43497.1 - 1.4e-06 27.9 0.0 3.8e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain RrnaAD PF00398.20 KXL43499.1 - 0.012 14.6 0.1 8.7 5.3 0.2 3.0 2 1 1 3 3 3 0 Ribosomal RNA adenine dimethylase CBS PF00571.28 KXL43499.1 - 0.064 13.7 4.8 9.3 6.8 0.1 4.0 3 0 0 3 3 3 0 CBS domain FliG_M PF14841.6 KXL43499.1 - 0.19 11.9 0.5 4.2 7.7 0.0 2.8 3 0 0 3 3 3 0 FliG middle domain Npa1 PF11707.8 KXL43499.1 - 1.6 8.0 4.5 6.8 5.9 0.1 3.2 3 1 1 4 4 4 0 Ribosome 60S biogenesis N-terminal Cullin PF00888.22 KXL43500.1 - 6.2e-175 583.3 0.0 8.2e-175 582.9 0.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KXL43500.1 - 7.8e-22 77.1 0.2 2.1e-21 75.7 0.2 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF3741 PF12552.8 KXL43500.1 - 0.12 12.3 1.1 0.31 11.0 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3741) UPF0086 PF01868.16 KXL43502.1 - 0.08 12.9 0.5 0.1 12.6 0.4 1.4 1 1 0 1 1 1 0 Domain of unknown function UPF0086 Git3 PF11710.8 KXL43503.1 - 5.3e-16 59.0 9.3 1.6e-15 57.5 9.3 1.8 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KXL43503.1 - 2.3e-05 24.4 0.1 6.2e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term FAD-oxidase_C PF02913.19 KXL43504.1 - 6.9e-66 222.4 0.0 9.7e-66 221.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KXL43504.1 - 9.8e-33 112.8 0.0 1.9e-32 111.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain SepSecS PF05889.13 KXL43504.1 - 0.017 13.8 0.1 0.028 13.1 0.1 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Vps62 PF06101.11 KXL43505.1 - 7.7e-11 41.0 2.2 1.2e-09 37.1 1.0 2.3 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 62 ERG4_ERG24 PF01222.17 KXL43506.1 - 1.9e-139 465.2 27.0 2.2e-139 464.9 27.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Fructosamin_kin PF03881.14 KXL43507.1 - 4.9e-71 239.3 0.0 5.8e-71 239.0 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KXL43507.1 - 3.8e-05 23.7 0.0 6.8e-05 22.9 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KXL43507.1 - 0.02 13.8 0.0 0.032 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) EcKinase PF02958.20 KXL43507.1 - 0.036 13.4 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase peroxidase PF00141.23 KXL43508.1 - 1.5e-83 280.0 0.0 6.8e-43 147.0 0.0 2.2 2 0 0 2 2 2 2 Peroxidase GST_C_3 PF14497.6 KXL43508.1 - 0.011 15.9 0.0 4.9 7.4 0.0 2.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain SCO1-SenC PF02630.14 KXL43509.1 - 6.1e-48 162.1 0.0 9e-48 161.6 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KXL43509.1 - 2e-05 24.5 0.0 3.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KXL43509.1 - 0.004 17.4 0.0 0.0099 16.2 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 KXL43509.1 - 0.027 14.2 0.0 0.12 12.1 0.0 1.8 1 1 0 1 1 1 0 Redoxin DUF3876 PF12992.7 KXL43509.1 - 0.13 12.3 0.1 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3876) TraF PF13728.6 KXL43509.1 - 0.18 11.6 0.0 0.98 9.2 0.0 1.9 2 0 0 2 2 2 0 F plasmid transfer operon protein Glyco_hydro_18 PF00704.28 KXL43510.1 - 2.3e-22 80.1 0.2 4e-22 79.3 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_1 PF00734.18 KXL43510.1 - 2e-10 40.4 10.2 2e-10 40.4 10.2 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain DUF4680 PF15730.5 KXL43510.1 - 0.17 12.2 3.7 0.35 11.2 3.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) SLT PF01464.20 KXL43511.1 - 0.0099 15.5 0.1 0.063 12.9 0.0 2.0 2 0 0 2 2 2 1 Transglycosylase SLT domain PhageMin_Tail PF10145.9 KXL43511.1 - 0.012 15.4 0.1 0.96 9.3 0.0 2.2 2 0 0 2 2 2 0 Phage-related minor tail protein tRNA_int_endo PF01974.17 KXL43511.1 - 0.18 11.9 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 tRNA intron endonuclease, catalytic C-terminal domain Pantoate_ligase PF02569.15 KXL43512.1 - 0.12 11.6 3.7 0.13 11.5 3.7 1.0 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase NB-ARC PF00931.22 KXL43513.1 - 0.00044 19.5 0.0 0.00055 19.2 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KXL43513.1 - 0.00096 19.6 2.2 0.012 16.0 2.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXL43513.1 - 0.0028 17.9 0.0 0.0045 17.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KXL43513.1 - 0.0046 16.6 0.0 0.006 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain GFO_IDH_MocA_C PF02894.17 KXL43514.1 - 5.7e-18 65.0 0.0 1.2e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.22 KXL43514.1 - 0.022 15.6 0.0 0.042 14.7 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Nnf1 PF03980.14 KXL43516.1 - 1.9e-21 76.5 2.2 2.7e-21 76.0 0.3 2.2 3 0 0 3 3 3 1 Nnf1 Baculo_PEP_C PF04513.12 KXL43516.1 - 0.088 12.8 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Atg14 PF10186.9 KXL43516.1 - 0.17 10.9 1.6 0.32 10.0 1.6 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-CpG_bind_C PF12269.8 KXL43516.1 - 0.19 11.5 1.9 1.8 8.3 0.5 2.1 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain ISG65-75 PF11727.8 KXL43516.1 - 1.6 7.9 3.2 2.4 7.3 1.4 1.9 2 0 0 2 2 2 0 Invariant surface glycoprotein SMC_N PF02463.19 KXL43517.1 - 5.8e-55 186.1 0.0 7.2e-53 179.3 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KXL43517.1 - 1.9e-27 95.9 0.0 6.8e-27 94.1 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 KXL43517.1 - 1.1e-11 45.0 0.8 1.1e-11 45.0 0.8 4.7 2 2 2 5 5 4 1 AAA ATPase domain AAA_21 PF13304.6 KXL43517.1 - 2.6e-10 40.6 14.5 4.6e-05 23.4 0.1 4.3 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXL43517.1 - 4.2e-07 29.6 0.0 8.2e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KXL43517.1 - 1.1e-06 29.3 30.2 1.1e-06 29.3 30.2 7.2 3 2 1 5 5 2 1 AAA domain DUF948 PF06103.11 KXL43517.1 - 0.0009 19.5 28.6 0.028 14.7 0.3 6.8 6 2 0 6 6 6 2 Bacterial protein of unknown function (DUF948) zf-C4H2 PF10146.9 KXL43517.1 - 0.00099 19.5 8.5 0.00099 19.5 8.5 6.7 4 1 2 6 6 5 1 Zinc finger-containing protein Fez1 PF06818.15 KXL43517.1 - 0.0034 17.9 14.3 0.0034 17.9 14.3 6.6 3 2 2 6 6 5 2 Fez1 SbcCD_C PF13558.6 KXL43517.1 - 0.0068 16.6 0.0 0.032 14.5 0.0 2.2 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SCA7 PF08313.12 KXL43517.1 - 0.029 14.2 0.7 3.2 7.7 0.1 3.0 2 0 0 2 2 2 0 SCA7, zinc-binding domain DUF2939 PF11159.8 KXL43517.1 - 0.11 12.9 0.2 0.74 10.3 0.2 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) HsbA PF12296.8 KXL43517.1 - 0.23 11.9 2.5 2.3 8.7 0.7 3.5 3 0 0 3 3 3 0 Hydrophobic surface binding protein A AAA_27 PF13514.6 KXL43517.1 - 0.25 10.9 0.0 0.25 10.9 0.0 6.7 6 2 2 8 8 8 0 AAA domain ABC_tran PF00005.27 KXL43517.1 - 0.36 11.3 0.0 0.36 11.3 0.0 6.6 4 2 0 5 5 4 0 ABC transporter ATG16 PF08614.11 KXL43517.1 - 1.8 8.7 111.3 1.6 8.9 7.7 7.2 4 2 1 5 5 5 0 Autophagy protein 16 (ATG16) DASH_Dam1 PF08653.10 KXL43517.1 - 3.4 7.5 8.7 31 4.5 0.1 4.7 4 0 0 4 4 4 0 DASH complex subunit Dam1 DUF1664 PF07889.12 KXL43517.1 - 4.7 7.3 63.5 0.2 11.7 1.5 8.6 5 3 4 9 9 9 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 KXL43517.1 - 7.1 6.6 64.1 0.077 13.0 4.8 7.3 5 2 3 8 8 8 0 Laminin Domain II Baculo_PEP_C PF04513.12 KXL43517.1 - 8.3 6.5 34.0 0.59 10.2 1.0 6.6 6 2 1 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus PSI_PsaF PF02507.15 KXL43517.1 - 9.2 6.1 6.5 95 2.8 1.0 4.0 3 0 0 3 3 3 0 Photosystem I reaction centre subunit III ZZ PF00569.17 KXL43518.1 - 3.3e-12 46.0 5.4 6.6e-12 45.1 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.32 KXL43518.1 - 1.8e-09 36.5 3.7 6.6e-05 22.2 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KXL43518.1 - 2.8e-06 26.8 2.6 0.076 13.0 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KXL43518.1 - 0.00016 22.1 6.1 0.00018 21.9 1.5 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 KXL43518.1 - 0.0012 18.7 3.7 0.25 11.2 0.3 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KXL43518.1 - 0.0012 18.2 5.4 0.38 10.3 0.1 3.2 3 0 0 3 3 3 2 EF hand Memo PF01875.17 KXL43519.1 - 1.9e-68 230.6 0.0 2.4e-68 230.2 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein Fe-ADH PF00465.19 KXL43521.1 - 1.3e-77 261.1 0.0 1.5e-77 260.9 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KXL43521.1 - 3.5e-12 46.6 0.0 4.5e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase FAD_binding_3 PF01494.19 KXL43522.1 - 1.2e-21 77.3 0.0 1.8e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXL43522.1 - 5.9e-06 26.1 0.0 0.014 15.0 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXL43522.1 - 0.00062 20.0 0.0 0.0018 18.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 KXL43522.1 - 0.00084 18.5 0.0 0.0034 16.5 0.0 1.9 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.14 KXL43522.1 - 0.0011 18.3 0.0 0.0028 17.0 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXL43522.1 - 0.0084 16.6 0.0 0.16 12.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXL43522.1 - 0.057 12.5 0.0 0.092 11.8 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 KXL43522.1 - 0.07 11.8 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.18 KXL43522.1 - 0.14 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KXL43522.1 - 0.19 11.0 0.0 0.34 10.2 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Peptidase_M24 PF00557.24 KXL43523.1 - 2.2e-49 168.0 0.0 2.7e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KXL43523.1 - 1.5e-19 70.0 9.8 3.2e-19 69.0 9.8 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KXL43523.1 - 0.00081 19.4 8.3 0.00081 19.4 8.3 2.4 2 0 0 2 2 2 1 MYND finger Cornichon PF03311.14 KXL43524.1 - 5.1e-50 168.9 11.5 5.9e-50 168.7 11.5 1.0 1 0 0 1 1 1 1 Cornichon protein Sugar_tr PF00083.24 KXL43525.1 - 1.1e-75 255.2 23.1 1.3e-75 255.0 23.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL43525.1 - 1.2e-25 90.2 29.3 2.1e-25 89.4 25.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily 7TM-7TMR_HD PF07698.11 KXL43525.1 - 1.3 8.7 12.5 0.073 12.8 3.2 3.0 3 0 0 3 3 3 0 7TM receptor with intracellular HD hydrolase adh_short PF00106.25 KXL43526.1 - 1.9e-34 118.8 0.0 6.8e-34 117.0 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL43526.1 - 1.3e-23 83.8 0.0 2.2e-23 83.0 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL43526.1 - 1.9e-08 34.4 0.0 2.8e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KXL43526.1 - 0.019 15.3 0.1 0.029 14.6 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KXL43526.1 - 0.071 13.0 0.2 0.12 12.2 0.2 1.4 1 1 0 1 1 1 0 NAD(P)H-binding PAS_9 PF13426.7 KXL43527.1 - 2.8e-15 56.4 0.0 2.1e-14 53.6 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 KXL43527.1 - 0.00011 22.2 0.0 0.00029 20.8 0.0 1.7 1 0 0 1 1 1 1 PAS fold PQ-loop PF04193.14 KXL43528.1 - 3e-13 49.3 1.0 4.3e-13 48.8 1.0 1.3 1 0 0 1 1 1 1 PQ loop repeat Form-deh_trans PF09163.11 KXL43528.1 - 0.16 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Formate dehydrogenase N, transmembrane IMPDH PF00478.25 KXL43529.1 - 4.9e-125 417.1 4.3 6.5e-125 416.7 4.3 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KXL43529.1 - 1.4e-18 67.0 0.2 1.2e-09 38.5 0.1 2.8 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 KXL43529.1 - 8.2e-09 34.9 1.1 2e-08 33.7 1.0 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 KXL43529.1 - 7e-06 25.6 5.9 0.0011 18.4 4.8 2.6 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 KXL43529.1 - 9.7e-05 21.9 2.4 0.017 14.6 0.1 3.1 2 1 1 3 3 3 2 Histidine biosynthesis protein Glu_synthase PF01645.17 KXL43529.1 - 0.035 13.2 1.6 0.059 12.5 1.6 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase ThiG PF05690.14 KXL43529.1 - 0.048 13.0 0.5 0.11 11.8 0.5 1.6 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG YpsA PF06908.11 KXL43529.1 - 0.14 12.1 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 YspA SLOG family RasGAP_C PF03836.15 KXL43530.1 - 5.4e-48 162.6 2.2 5.4e-48 162.6 2.2 2.2 2 0 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.19 KXL43530.1 - 3.7e-34 118.2 0.0 5.7e-33 114.4 0.0 2.5 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.27 KXL43530.1 - 2.1e-14 51.9 44.4 0.1 12.5 1.0 14.5 15 0 0 15 15 15 7 IQ calmodulin-binding motif CH PF00307.31 KXL43530.1 - 1.4e-10 41.3 0.0 4.9e-10 39.5 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KXL43530.1 - 0.06 13.2 0.1 2.1 8.2 0.0 2.9 3 0 0 3 3 3 0 CAMSAP CH domain Ribosomal_S19e PF01090.19 KXL43531.1 - 2.4e-59 198.9 0.3 2.8e-59 198.7 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Abhydrolase_6 PF12697.7 KXL43532.1 - 4.6e-15 56.8 0.0 8.6e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXL43532.1 - 2e-14 53.8 0.0 7.6e-14 52.0 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold DSPc PF00782.20 KXL43532.1 - 2e-09 37.4 0.0 5.4e-09 36.0 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Hydrolase_4 PF12146.8 KXL43532.1 - 2e-08 33.8 0.0 2.1e-07 30.5 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KXL43532.1 - 2.4e-05 24.6 0.0 6.8e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 Thioesterase domain PGAP1 PF07819.13 KXL43532.1 - 0.00096 18.9 0.1 0.042 13.6 0.1 2.3 2 0 0 2 2 2 1 PGAP1-like protein Y_phosphatase PF00102.27 KXL43532.1 - 0.017 14.7 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF3089 PF11288.8 KXL43532.1 - 0.024 14.2 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) LCAT PF02450.15 KXL43532.1 - 0.032 13.4 0.0 0.072 12.2 0.0 1.5 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase LIDHydrolase PF10230.9 KXL43532.1 - 0.058 12.9 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase PTPlike_phytase PF14566.6 KXL43532.1 - 0.075 13.2 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 KXL43532.1 - 0.12 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family RRM_1 PF00076.22 KXL43535.1 - 1.4e-15 56.9 0.0 2.1e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXL43535.1 - 0.0029 17.2 0.0 0.0042 16.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KXL43535.1 - 0.015 15.4 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif p450 PF00067.22 KXL43536.1 - 4.5e-60 203.7 0.0 6.1e-60 203.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 KXL43537.1 - 3.6e-22 79.0 0.0 5e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL43537.1 - 8.7e-11 42.4 0.0 5.6e-10 39.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL43537.1 - 2.5e-09 37.1 0.0 0.0019 18.0 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KXL43537.1 - 1.8e-08 35.0 0.1 5.1e-07 30.4 0.0 2.7 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL43537.1 - 1.5e-06 28.7 0.0 3.4e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXL43537.1 - 0.00017 21.2 0.0 0.00083 18.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KXL43537.1 - 0.00074 18.9 0.0 0.018 14.4 0.0 2.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KXL43537.1 - 0.00083 18.9 0.1 0.0037 16.8 0.0 2.0 3 0 0 3 3 3 1 Putative methyltransferase FtsJ PF01728.19 KXL43537.1 - 0.011 15.9 0.0 0.036 14.2 0.0 1.8 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 KXL43537.1 - 0.049 13.4 0.0 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase DUF938 PF06080.12 KXL43537.1 - 0.063 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_2 PF00891.18 KXL43537.1 - 0.066 12.5 0.0 2.8 7.2 0.0 2.3 2 0 0 2 2 2 0 O-methyltransferase domain Nucleoporin_N PF08801.11 KXL43537.1 - 0.072 11.8 0.1 0.1 11.3 0.1 1.1 1 0 0 1 1 1 0 Nup133 N terminal like PCMT PF01135.19 KXL43537.1 - 0.098 12.4 0.0 0.98 9.1 0.0 2.1 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pkinase PF00069.25 KXL43538.1 - 3.7e-68 229.8 0.0 6.4e-68 229.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL43538.1 - 3.2e-47 161.0 0.0 5e-47 160.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 KXL43538.1 - 1.2e-22 80.1 0.0 2.3e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.30 KXL43538.1 - 4.1e-17 62.4 0.1 1.4e-16 60.7 0.1 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KXL43538.1 - 3.9e-15 55.7 0.0 9.2e-15 54.5 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 KXL43538.1 - 2e-06 27.4 0.0 0.0017 17.7 0.0 2.4 2 0 0 2 2 2 2 Kinase-like RA PF00788.23 KXL43538.1 - 4.6e-05 24.0 0.0 8.6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_4 PF18017.1 KXL43538.1 - 0.0044 16.9 0.1 0.0098 15.8 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Seadorna_VP7 PF07387.11 KXL43538.1 - 0.0077 15.3 0.2 0.025 13.7 0.1 1.8 2 0 0 2 2 2 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 KXL43538.1 - 0.043 12.6 0.1 0.08 11.7 0.1 1.4 1 0 0 1 1 1 0 Fungal protein kinase Pico_P2A PF00947.19 KXL43540.1 - 0.055 13.5 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Picornavirus core protein 2A DNA_pol3_delta2 PF13177.6 KXL43541.1 - 1.8e-11 44.1 0.1 4.5e-11 42.8 0.1 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KXL43541.1 - 2.1e-06 28.2 0.1 4.4e-06 27.1 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 KXL43541.1 - 3.4e-05 24.2 0.2 0.00017 21.9 0.0 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA_22 PF13401.6 KXL43541.1 - 0.00028 21.2 0.5 0.0035 17.6 0.3 2.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXL43541.1 - 0.00037 20.9 1.6 0.011 16.1 0.8 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 KXL43541.1 - 0.002 17.9 0.4 0.0053 16.5 0.4 1.6 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KXL43541.1 - 0.0088 16.6 0.0 0.038 14.5 0.0 2.0 1 1 0 1 1 1 1 ABC transporter Rad17 PF03215.15 KXL43541.1 - 0.018 14.9 0.0 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_29 PF13555.6 KXL43541.1 - 0.047 13.4 0.1 0.46 10.3 0.0 2.4 2 1 1 3 3 3 0 P-loop containing region of AAA domain T4SS-DNA_transf PF02534.14 KXL43541.1 - 0.049 12.4 0.1 0.22 10.3 0.0 1.8 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer 2-Hacid_dh_C PF02826.19 KXL43542.1 - 2.7e-40 137.6 0.0 3.6e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXL43542.1 - 7.4e-19 67.7 0.0 9e-19 67.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXL43542.1 - 0.0002 21.5 0.0 0.00034 20.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NTP_transf_3 PF12804.7 KXL43542.1 - 0.1 12.9 0.0 0.25 11.7 0.0 1.6 2 0 0 2 2 2 0 MobA-like NTP transferase domain cIII PF08134.11 KXL43542.1 - 0.14 11.9 0.0 0.43 10.4 0.0 1.8 1 0 0 1 1 1 0 cIII protein family SKG6 PF08693.10 KXL43543.1 - 3.7e-09 35.8 0.5 6.2e-09 35.1 0.5 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF2062 PF09835.9 KXL43543.1 - 0.022 14.6 0.6 0.022 14.6 0.5 1.2 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF4448 PF14610.6 KXL43543.1 - 0.036 13.8 0.0 0.036 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF5134 PF17197.4 KXL43543.1 - 0.046 13.6 1.6 0.053 13.4 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5134) RTX PF02382.15 KXL43543.1 - 0.18 11.4 3.8 0.2 11.3 3.8 1.1 1 0 0 1 1 1 0 N-terminal domain in RTX protein Aldo_ket_red PF00248.21 KXL43545.1 - 1.4e-49 168.9 0.0 1.8e-49 168.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MR_MLE_C PF13378.6 KXL43546.1 - 3.5e-14 52.9 0.0 4.5e-09 36.2 0.0 2.2 1 1 1 2 2 2 2 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KXL43546.1 - 9.2e-06 25.9 0.0 1.7e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain AKAP7_NLS PF10469.9 KXL43547.1 - 3e-19 69.7 0.0 4.1e-18 66.0 0.0 2.1 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain GET2 PF08690.10 KXL43548.1 - 8.4e-29 101.2 2.7 1.8e-28 100.2 2.7 1.5 1 1 0 1 1 1 1 GET complex subunit GET2 Vma12 PF11712.8 KXL43548.1 - 0.47 10.5 2.0 18 5.3 0.0 2.5 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase L51_S25_CI-B8 PF05047.16 KXL43549.1 - 1.6e-16 60.0 0.0 4e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain PGBA_C PF15437.6 KXL43549.1 - 0.025 14.9 2.6 0.036 14.4 2.6 1.3 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal DivIC PF04977.15 KXL43549.1 - 0.028 14.2 1.7 0.052 13.3 1.7 1.4 1 0 0 1 1 1 0 Septum formation initiator Ribosomal_L28 PF00830.19 KXL43550.1 - 4.2e-19 68.5 0.9 6.8e-19 67.8 0.9 1.3 1 0 0 1 1 1 1 Ribosomal L28 family Sde2_N_Ubi PF13019.6 KXL43552.1 - 6.7e-63 211.4 0.1 1.3e-62 210.5 0.1 1.4 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain TP53IP5 PF15331.6 KXL43552.1 - 0.55 10.3 5.5 0.86 9.7 5.5 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 p450 PF00067.22 KXL43553.1 - 9.6e-62 209.2 0.1 1.3e-61 208.8 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 Flavodoxin_1 PF00258.25 KXL43553.1 - 4e-22 79.0 0.0 9e-22 77.8 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 KXL43553.1 - 5.3e-21 75.2 0.0 8.8e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KXL43553.1 - 2.3e-11 44.3 0.1 4.8e-10 40.1 0.0 2.9 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KXL43553.1 - 0.0022 18.3 0.0 0.0047 17.2 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin domain p450 PF00067.22 KXL43554.1 - 0.096 11.4 0.0 0.1 11.3 0.0 1.0 1 0 0 1 1 1 0 Cytochrome P450 Dimer_Tnp_hAT PF05699.14 KXL43556.1 - 2e-08 33.9 0.0 2.1e-08 33.8 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RRM_1 PF00076.22 KXL43557.1 - 1.5e-06 27.9 0.0 3.7e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 KXL43557.1 - 0.04 14.5 0.0 0.064 13.8 0.0 1.3 1 0 0 1 1 1 0 Exonuclease Presenilin PF01080.17 KXL43558.1 - 3.7 6.2 5.5 6.2 5.5 5.5 1.3 1 0 0 1 1 1 0 Presenilin Na_Ca_ex PF01699.24 KXL43559.1 - 5.9e-38 130.2 43.1 9.2e-21 74.4 14.7 2.5 3 0 0 3 3 3 2 Sodium/calcium exchanger protein hNIFK_binding PF12196.8 KXL43560.1 - 5.2 6.7 6.0 1.2 8.7 0.1 2.6 3 0 0 3 3 3 0 FHA Ki67 binding domain of hNIFK Sugar_tr PF00083.24 KXL43561.1 - 1.4e-94 317.5 23.2 1.8e-94 317.2 23.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL43561.1 - 6.1e-25 87.9 21.3 6.1e-25 87.9 21.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily GCP_N_terminal PF17681.1 KXL43563.1 - 3.2e-27 96.0 0.0 6.2e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KXL43563.1 - 4.7e-21 75.6 0.0 9.4e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Apolipoprotein PF01442.18 KXL43563.1 - 0.17 11.8 2.0 0.13 12.1 0.3 1.7 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain WD40 PF00400.32 KXL43565.1 - 4.8e-10 39.9 17.8 0.019 15.8 0.2 6.7 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL43565.1 - 0.00025 21.3 1.3 0.21 11.9 0.0 4.4 4 2 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain FBPase PF00316.20 KXL43565.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain DEAD PF00270.29 KXL43566.1 - 6.7e-41 140.0 0.0 1.1e-40 139.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXL43566.1 - 1.6e-20 73.5 0.0 5.5e-20 71.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KXL43566.1 - 1.6e-17 63.5 0.6 1.3e-16 60.6 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KXL43566.1 - 6.4e-07 29.5 0.0 1.4e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KXL43566.1 - 0.027 13.7 0.0 0.046 12.9 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase HTH_Mga PF08280.11 KXL43566.1 - 0.18 11.9 0.1 7.9 6.6 0.0 2.5 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain Pantoate_ligase PF02569.15 KXL43567.1 - 2.7e-94 315.3 0.0 3.1e-94 315.1 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase ThiF PF00899.21 KXL43568.1 - 8.1e-111 369.2 0.0 1.1e-75 254.1 0.0 2.4 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KXL43568.1 - 4.5e-94 315.1 3.1 2e-93 312.9 1.4 2.4 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 KXL43568.1 - 6.4e-34 116.5 0.3 1.7e-33 115.2 0.3 1.8 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 KXL43568.1 - 7.9e-33 112.5 0.3 2.4e-32 111.0 0.3 1.9 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 KXL43568.1 - 5.5e-27 93.7 0.8 3.8e-26 91.1 0.7 2.4 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle F-box-like PF12937.7 KXL43569.1 - 0.13 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 F-box-like TP53IP5 PF15331.6 KXL43570.1 - 1.2 9.2 8.7 1.4 9.1 8.7 1.0 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 HA2 PF04408.23 KXL43571.1 - 2.7e-21 75.9 1.7 4.6e-21 75.1 0.1 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KXL43571.1 - 4.7e-21 74.9 0.0 1.1e-20 73.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KXL43571.1 - 5.8e-14 52.4 0.0 2.5e-13 50.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain S1 PF00575.23 KXL43571.1 - 1.4e-11 44.5 2.0 1.4e-11 44.5 2.0 1.8 2 0 0 2 2 2 1 S1 RNA binding domain DEAD PF00270.29 KXL43571.1 - 0.00024 20.9 0.1 0.00051 19.9 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KXL43571.1 - 0.00056 20.2 0.1 0.0023 18.2 0.1 2.1 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 KXL43571.1 - 0.00069 18.8 0.0 0.0027 16.8 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 KXL43571.1 - 0.0019 17.9 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KXL43571.1 - 0.063 13.8 0.2 0.68 10.4 0.2 2.4 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 KXL43571.1 - 0.067 13.2 0.2 1.2 9.2 0.2 2.4 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 KXL43571.1 - 0.08 12.4 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.6 KXL43571.1 - 0.13 12.4 1.9 0.24 11.6 0.0 2.6 3 0 0 3 3 2 0 AAA domain MatE PF01554.18 KXL43572.1 - 1.5e-60 203.5 30.0 4.8e-37 127.1 9.7 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KXL43572.1 - 9.4e-07 29.0 9.8 9.4e-07 29.0 9.8 3.2 4 0 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain TAP42 PF04177.12 KXL43573.1 - 1e-103 346.8 2.1 1.2e-103 346.7 2.1 1.0 1 0 0 1 1 1 1 TAP42-like family Dicer_dimer PF03368.14 KXL43574.1 - 2.7e-22 78.7 0.2 1.4e-21 76.5 0.1 2.3 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.31 KXL43574.1 - 2.9e-16 59.8 0.0 9.3e-16 58.2 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXL43574.1 - 6.1e-12 45.7 0.0 1.2e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KXL43574.1 - 4.9e-11 42.9 0.0 1.2e-10 41.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ribonuclease_3 PF00636.26 KXL43574.1 - 1.2e-10 42.0 0.0 6.9e-10 39.5 0.0 2.4 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KXL43574.1 - 3.4e-06 27.2 0.0 7.4e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease-III-like Hamartin PF04388.12 KXL43575.1 - 1.8e-14 53.4 41.3 1.8e-14 53.4 41.3 3.2 1 1 1 2 2 2 1 Hamartin protein DNA_gyraseA_C PF03989.13 KXL43575.1 - 0.074 12.5 0.2 0.15 11.6 0.2 1.5 1 0 0 1 1 1 0 DNA gyrase C-terminal domain, beta-propeller PAPS_reduct PF01507.19 KXL43576.1 - 8.6e-28 97.5 0.0 7.8e-25 87.9 0.0 2.2 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Nucleoporin_FG PF13634.6 KXL43577.1 - 7.4e-09 36.3 108.5 2.9e-06 28.1 29.9 3.7 1 1 3 4 4 4 3 Nucleoporin FG repeat region DUF1664 PF07889.12 KXL43577.1 - 0.037 14.1 2.1 0.15 12.1 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) MCC-bdg_PDZ PF10506.9 KXL43577.1 - 0.055 13.5 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Dynactin_p22 PF07426.11 KXL43577.1 - 0.083 12.7 0.1 0.77 9.6 0.0 2.1 2 0 0 2 2 2 0 Dynactin subunit p22 Syntaxin-6_N PF09177.11 KXL43577.1 - 0.16 12.5 1.5 4.8 7.8 0.0 3.1 2 1 0 2 2 2 0 Syntaxin 6, N-terminal XhlA PF10779.9 KXL43577.1 - 0.29 11.4 6.4 5.1 7.4 0.0 3.3 3 1 1 4 4 4 0 Haemolysin XhlA NPV_P10 PF05531.12 KXL43577.1 - 0.31 11.5 1.5 40 4.8 0.2 3.2 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Tropomyosin PF00261.20 KXL43577.1 - 1.1 8.6 6.3 0.72 9.2 0.3 2.1 2 0 0 2 2 2 0 Tropomyosin TFIIA PF03153.13 KXL43577.1 - 3.1 7.7 20.8 4.6 7.1 20.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Fip1 PF05182.13 KXL43578.1 - 1.1e-19 69.6 0.8 1.9e-19 68.9 0.8 1.4 1 0 0 1 1 1 1 Fip1 motif YL1 PF05764.13 KXL43578.1 - 0.0036 17.5 7.9 0.0047 17.1 7.9 1.1 1 0 0 1 1 1 1 YL1 nuclear protein PTPRCAP PF15713.5 KXL43578.1 - 1.3 9.3 8.2 0.71 10.1 5.9 1.7 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated ADH_zinc_N PF00107.26 KXL43579.1 - 2.4e-28 98.7 0.2 3.8e-28 98.0 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXL43579.1 - 2.1e-13 51.4 0.0 5e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXL43579.1 - 1.6e-07 31.2 0.0 4.3e-07 29.8 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KXL43579.1 - 0.0029 17.8 0.0 0.0051 17.1 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain tRNA_int_endo PF01974.17 KXL43580.1 - 3.8e-15 55.7 0.0 7.2e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Rho_GDI PF02115.17 KXL43581.1 - 7.3e-42 143.3 0.2 8.6e-42 143.1 0.2 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor KilA-N PF04383.13 KXL43582.1 - 4.2e-05 23.3 0.0 0.00031 20.6 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain OsmC PF02566.19 KXL43582.1 - 0.012 16.1 0.1 0.025 15.0 0.1 1.5 1 0 0 1 1 1 0 OsmC-like protein DUF883 PF05957.13 KXL43582.1 - 0.082 13.5 0.3 0.082 13.5 0.3 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) SOG2 PF10428.9 KXL43582.1 - 7 5.7 8.5 9.2 5.3 8.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Thioredoxin PF00085.20 KXL43583.1 - 1.4e-25 89.2 0.0 1.9e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 KXL43583.1 - 0.0002 21.1 0.0 0.00028 20.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KXL43583.1 - 0.0004 20.8 0.2 0.001 19.5 0.2 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KXL43583.1 - 0.0029 17.0 0.0 0.004 16.5 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KXL43583.1 - 0.0062 16.9 0.0 0.061 13.7 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like DNA_binding_2 PF13724.6 KXL43583.1 - 0.029 14.8 0.0 0.071 13.5 0.0 1.6 1 0 0 1 1 1 0 DNA-binding domain HyaE PF07449.11 KXL43583.1 - 0.13 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE zf-C3HC4_2 PF13923.6 KXL43586.1 - 4.7e-12 45.5 11.2 1e-11 44.5 11.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXL43586.1 - 1.2e-08 34.6 11.4 2.7e-08 33.5 11.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXL43586.1 - 1.4e-08 34.6 11.2 3.2e-08 33.4 11.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXL43586.1 - 1.1e-07 31.7 11.1 2.8e-07 30.5 11.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXL43586.1 - 1.2e-06 28.2 8.0 2.4e-06 27.3 8.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXL43586.1 - 1.8e-06 28.1 11.6 3.7e-06 27.2 11.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KXL43586.1 - 1.2e-05 25.4 10.6 2.6e-05 24.3 10.6 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Mob_synth_C PF06463.13 KXL43586.1 - 1.7e-05 24.8 1.9 3.7e-05 23.7 1.9 1.6 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C SAP PF02037.27 KXL43586.1 - 2.6e-05 23.8 0.0 5.7e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 SAP domain zf-RING_10 PF16685.5 KXL43586.1 - 9.7e-05 22.4 3.5 9.7e-05 22.4 3.5 1.8 2 0 0 2 2 2 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 KXL43586.1 - 0.00016 21.4 7.9 0.00016 21.4 7.9 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KXL43586.1 - 0.00027 20.8 2.4 0.00046 20.0 2.4 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 KXL43586.1 - 0.00079 19.7 8.0 0.003 17.8 8.0 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain U-box PF04564.15 KXL43586.1 - 0.0012 19.0 0.0 0.0034 17.5 0.0 1.7 1 0 0 1 1 1 1 U-box domain Rubredoxin_2 PF18073.1 KXL43586.1 - 0.02 14.6 0.5 0.02 14.6 0.5 2.1 3 0 0 3 3 3 0 Rubredoxin metal binding domain DUF1272 PF06906.11 KXL43586.1 - 0.088 12.9 7.1 0.21 11.7 7.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-P11 PF03854.14 KXL43586.1 - 0.1 12.3 5.8 0.3 10.8 5.9 1.7 1 1 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.6 KXL43586.1 - 0.11 12.3 7.6 0.7 9.7 7.7 2.2 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 KXL43586.1 - 1.4 8.8 7.0 3.2 7.6 7.0 1.7 1 1 0 1 1 1 0 RING-like zinc finger TRAPPC-Trs85 PF12739.7 KXL43588.1 - 8.7e-112 374.1 0.0 2e-111 372.9 0.0 1.5 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Fungal_trans PF04082.18 KXL43589.1 - 1.1e-43 149.2 0.0 2e-43 148.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL43589.1 - 6.1e-08 32.7 8.5 1.2e-07 31.7 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Alpha-mann_mid PF09261.11 KXL43590.1 - 0.03 14.4 0.7 0.041 14.0 0.7 1.2 1 0 0 1 1 1 0 Alpha mannosidase middle domain TMF_TATA_bd PF12325.8 KXL43590.1 - 0.36 11.1 6.6 0.41 10.9 6.6 1.0 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding bZIP_1 PF00170.21 KXL43590.1 - 0.5 10.5 13.6 1.9 8.6 13.6 1.9 1 1 0 1 1 1 0 bZIP transcription factor CENP-H PF05837.12 KXL43590.1 - 1.8 9.0 7.1 2.1 8.8 7.1 1.0 1 0 0 1 1 1 0 Centromere protein H (CENP-H) PolyA_pol PF01743.20 KXL43591.1 - 7e-22 78.2 4.6 7.8e-21 74.8 1.8 2.8 2 1 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KXL43591.1 - 8.8e-07 28.6 0.0 2.1e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 KXL43591.1 - 9.5e-05 22.4 0.0 0.00018 21.5 0.0 1.4 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative Snf7 PF03357.21 KXL43592.1 - 1.4e-15 57.3 22.7 1.5e-15 57.3 21.1 1.7 1 1 1 2 2 2 1 Snf7 CorA PF01544.18 KXL43592.1 - 7.9e-05 22.1 1.5 0.00014 21.3 1.5 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein FlaC_arch PF05377.11 KXL43592.1 - 0.096 13.1 0.3 0.096 13.1 0.3 3.3 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) E2R135 PF11570.8 KXL43592.1 - 0.096 13.0 4.8 0.33 11.3 0.0 2.6 1 1 0 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 NPV_P10 PF05531.12 KXL43592.1 - 0.19 12.2 10.7 0.54 10.7 2.8 3.6 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein TraB PF01963.17 KXL43592.1 - 0.36 10.7 11.5 0.051 13.5 7.4 1.7 2 0 0 2 2 2 0 TraB family ProSAAS PF07259.12 KXL43592.1 - 0.39 10.7 3.8 1.1 9.2 3.8 1.7 1 0 0 1 1 1 0 ProSAAS precursor Arteri_nsp7a PF16749.5 KXL43592.1 - 0.57 10.4 4.0 3.5 7.8 0.6 3.5 4 0 0 4 4 4 0 Arterivirus nonstructural protein 7 alpha DASH_Dam1 PF08653.10 KXL43592.1 - 0.61 9.9 2.4 33 4.4 0.0 3.8 4 0 0 4 4 4 0 DASH complex subunit Dam1 BUD22 PF09073.10 KXL43592.1 - 1.4 8.2 13.5 2 7.7 13.5 1.2 1 0 0 1 1 1 0 BUD22 Sec20 PF03908.13 KXL43592.1 - 3.5 7.6 8.1 2.7 8.0 0.2 3.2 2 1 2 4 4 4 0 Sec20 ABC_tran PF00005.27 KXL43594.1 - 2.3e-19 70.2 0.0 4.7e-09 36.9 0.0 2.9 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KXL43594.1 - 5e-06 26.5 1.1 0.024 14.5 0.0 2.7 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KXL43594.1 - 0.00025 21.2 0.0 0.35 11.1 0.0 2.6 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 KXL43594.1 - 0.11 13.0 0.4 0.19 12.2 0.4 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KXL43594.1 - 0.11 12.8 0.1 1.2 9.4 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 KXL43594.1 - 0.17 11.7 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NAD_binding_2 PF03446.15 KXL43595.1 - 1.9e-35 122.4 0.0 2.8e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXL43595.1 - 1.9e-26 92.7 0.0 3.5e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KXL43595.1 - 3.7e-05 24.2 0.0 8.7e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 KXL43595.1 - 0.037 14.9 0.0 0.064 14.1 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Ctr PF04145.15 KXL43596.1 - 4.9e-33 114.8 0.0 5.9e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Amelogenin PF02948.15 KXL43597.1 - 0.043 14.5 13.8 0.063 13.9 13.8 1.4 1 0 0 1 1 1 0 Amelogenin RNA_pol_Rbc25 PF08292.12 KXL43599.1 - 6.2e-26 91.1 0.1 1e-25 90.5 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KXL43599.1 - 1.3e-14 54.3 0.1 2.3e-14 53.5 0.1 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 NUFIP1 PF10453.9 KXL43600.1 - 8.5e-11 41.5 2.3 2.8e-10 39.9 2.3 2.0 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.24 KXL43600.1 - 2.6e-08 33.6 2.5 4.4e-08 32.8 2.5 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KXL43600.1 - 8.8e-06 25.6 6.6 1.5e-05 24.9 6.6 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 KXL43600.1 - 0.00054 19.7 5.7 0.00093 18.9 5.7 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 KXL43600.1 - 0.008 16.9 0.3 0.027 15.2 0.3 1.9 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 KXL43600.1 - 0.14 12.7 3.0 0.38 11.3 3.0 1.8 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger DUF3546 PF12066.8 KXL43601.1 - 2.1e-32 111.6 4.1 5.3e-32 110.3 4.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) DUF4187 PF13821.6 KXL43601.1 - 7.8e-14 51.2 0.4 1.7e-13 50.1 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.13 KXL43601.1 - 3e-12 47.3 0.0 7e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Arsenite-resistance protein 2 Vma12 PF11712.8 KXL43602.1 - 6.8 6.8 5.5 17 5.5 5.1 1.9 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF1772 PF08592.11 KXL43603.1 - 1.7e-16 60.8 3.1 2e-16 60.5 3.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) CRF PF00473.17 KXL43603.1 - 0.15 12.1 0.2 0.3 11.2 0.2 1.5 1 0 0 1 1 1 0 Corticotropin-releasing factor family Glyco_hydro_28 PF00295.17 KXL43604.1 - 3e-47 161.3 10.6 4.5e-47 160.7 10.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF1772 PF08592.11 KXL43605.1 - 8.3e-18 65.0 2.5 1.3e-17 64.4 1.5 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF1772) Abhydrolase_6 PF12697.7 KXL43606.1 - 1.3e-13 52.1 0.0 8.6e-12 46.1 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXL43606.1 - 1.1e-10 41.6 0.4 3.8e-08 33.3 0.2 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXL43606.1 - 2.1e-09 37.0 0.0 4.4e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KXL43606.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein EHN PF06441.12 KXL43606.1 - 0.12 12.7 0.2 0.23 11.8 0.2 1.5 1 0 0 1 1 1 0 Epoxide hydrolase N terminus AA_permease_2 PF13520.6 KXL43608.1 - 3.4e-45 154.6 55.7 4.6e-45 154.2 55.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXL43608.1 - 2.9e-23 82.2 51.5 4.1e-23 81.7 51.5 1.1 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_10 PF13673.7 KXL43610.1 - 1.6e-09 37.8 0.0 4.2e-09 36.4 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXL43610.1 - 2.2e-09 37.6 0.0 6.4e-09 36.1 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXL43610.1 - 4.2e-09 36.7 0.0 1.2e-08 35.3 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 KXL43610.1 - 0.019 14.6 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family FR47 PF08445.10 KXL43610.1 - 0.1 12.6 0.0 0.55 10.2 0.0 2.2 2 0 0 2 2 2 0 FR47-like protein Pro-kuma_activ PF09286.11 KXL43611.1 - 2.4e-39 134.8 0.0 4e-39 134.1 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Pyr_redox_2 PF07992.14 KXL43614.1 - 1.3e-12 47.6 0.0 1.6e-11 44.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXL43614.1 - 9.8e-11 40.8 0.5 2.2e-10 39.6 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXL43614.1 - 2.1e-09 37.1 0.0 2.6e-05 23.6 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXL43614.1 - 4.2e-08 33.3 0.0 1.3e-05 25.4 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXL43614.1 - 6.5e-06 25.5 0.0 7e-05 22.1 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 KXL43614.1 - 7.6e-05 21.9 0.0 0.0049 16.0 0.0 2.5 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 KXL43614.1 - 0.048 14.2 0.1 25 5.5 0.0 3.0 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Myb_DNA-bind_6 PF13921.6 KXL43615.1 - 0.24 11.7 0.1 0.24 11.7 0.1 1.6 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF92 PF01940.16 KXL43616.1 - 2e-69 233.6 11.3 2.3e-69 233.4 11.3 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 DUF1646 PF07854.12 KXL43616.1 - 0.011 15.1 0.2 0.017 14.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1646) SPC12 PF06645.13 KXL43616.1 - 2.3 8.4 4.9 0.58 10.3 0.6 2.3 2 1 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) LIP PF03583.14 KXL43617.1 - 6.2e-69 232.5 0.0 8.4e-69 232.1 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase ADH_zinc_N PF00107.26 KXL43618.1 - 1.5e-06 28.2 0.3 2.4e-06 27.6 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXL43618.1 - 1.7e-06 27.9 0.0 6e-06 26.1 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.21 KXL43618.1 - 0.011 15.2 0.1 0.016 14.7 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF4965 PF16335.5 KXL43620.1 - 7.7e-59 198.2 0.1 1.3e-58 197.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF5127 PF17168.4 KXL43620.1 - 2.5e-43 148.5 4.1 4e-43 147.8 4.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF1793 PF08760.11 KXL43620.1 - 1.5e-23 84.1 0.3 1.5e-23 84.1 0.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KXL43620.1 - 3.9e-07 29.5 0.0 9.1e-07 28.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Glyco_hydr_116N PF12215.8 KXL43620.1 - 3.1e-05 23.6 0.3 5.6e-05 22.8 0.3 1.3 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term DHquinase_I PF01487.15 KXL43623.1 - 6e-44 151.0 0.0 9.7e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Fungal_trans PF04082.18 KXL43625.1 - 4.1e-19 68.6 0.0 4.1e-19 68.6 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL43625.1 - 1.2e-07 31.8 11.9 2e-07 31.0 11.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 KXL43625.1 - 0.0088 16.1 34.2 0.012 15.6 21.3 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Striatin PF08232.12 KXL43625.1 - 1.9 9.0 20.9 1.9 9.1 9.6 2.3 2 0 0 2 2 2 0 Striatin family Suf PF05843.14 KXL43625.1 - 4.4 7.2 20.3 1.7 8.5 7.9 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Zip PF02535.22 KXL43625.1 - 6.2 5.9 7.8 3.3 6.8 0.1 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter FAM60A PF15396.6 KXL43625.1 - 7.6 6.5 12.6 3.4 7.6 2.3 2.4 2 0 0 2 2 2 0 Protein Family FAM60A Steroid_dh PF02544.16 KXL43626.1 - 8e-17 61.6 0.9 8e-17 61.6 0.9 2.4 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KXL43626.1 - 0.03 13.8 2.8 0.078 12.5 2.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) Ribonuc_red_lgC PF02867.15 KXL43628.1 - 4.5e-189 629.3 0.0 5.7e-189 629.0 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KXL43628.1 - 2.3e-24 85.2 0.1 5.4e-24 84.0 0.1 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KXL43628.1 - 1.1e-16 61.1 0.0 2.8e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 ATP cone domain CTP_transf_like PF01467.26 KXL43629.1 - 1e-22 80.9 0.0 2.6e-18 66.6 0.0 2.6 2 1 0 2 2 2 2 Cytidylyltransferase-like CHD5 PF04420.14 KXL43630.1 - 5.8e-57 192.0 2.7 7e-57 191.7 2.7 1.0 1 0 0 1 1 1 1 CHD5-like protein TPR_MLP1_2 PF07926.12 KXL43630.1 - 0.14 12.2 2.1 0.48 10.5 2.1 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF202 PF02656.15 KXL43631.1 - 2e-14 53.8 3.5 2e-14 53.8 3.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF5337 PF17272.2 KXL43631.1 - 2.2 8.2 9.6 0.39 10.6 4.8 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5337) Tctex-1 PF03645.13 KXL43632.1 - 5.1e-38 129.5 0.0 5.8e-38 129.3 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family Thioredoxin_16 PF18569.1 KXL43632.1 - 0.06 13.5 0.2 0.11 12.6 0.2 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain Lyase_1 PF00206.20 KXL43634.1 - 5.7e-96 321.6 0.0 8.3e-96 321.0 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 KXL43634.1 - 1.6e-22 80.0 0.0 6.6e-22 78.0 0.0 2.1 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal CSN7a_helixI PF18392.1 KXL43634.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain Vfa1 PF08432.10 KXL43635.1 - 1.8e-41 142.4 17.1 2.1e-41 142.3 17.1 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Vma12 PF11712.8 KXL43635.1 - 0.14 12.2 2.5 0.16 12.0 2.5 1.3 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase SET PF00856.28 KXL43635.1 - 0.26 11.7 2.2 0.33 11.3 2.2 1.3 1 0 0 1 1 1 0 SET domain Paramyxo_ncap PF00973.19 KXL43635.1 - 8.7 5.1 9.8 11 4.8 9.8 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein PRIMA1 PF16101.5 KXL43636.1 - 0.2 11.7 7.4 0.4 10.7 7.4 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 zf-C2H2 PF00096.26 KXL43637.1 - 0.00044 20.6 22.0 0.017 15.5 1.7 4.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXL43637.1 - 0.0065 16.9 0.5 0.0065 16.9 0.5 4.5 4 1 0 4 4 4 1 Zinc-finger double domain PyrI_C PF02748.15 KXL43637.1 - 0.3 11.0 10.6 1.8 8.5 0.0 2.8 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_4 PF13894.6 KXL43637.1 - 0.51 11.3 26.3 0.49 11.4 2.2 5.0 5 0 0 5 5 5 0 C2H2-type zinc finger zf-CHCC PF10276.9 KXL43637.1 - 0.89 9.7 6.4 1.2 9.2 0.2 2.9 3 0 0 3 3 3 0 Zinc-finger domain zf-C2H2_jaz PF12171.8 KXL43637.1 - 5.8 7.3 17.3 0.4 11.0 5.1 3.8 3 1 1 4 4 4 0 Zinc-finger double-stranded RNA-binding Pkinase PF00069.25 KXL43638.1 - 8.9e-65 218.7 0.0 1.2e-64 218.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL43638.1 - 2.6e-22 79.4 0.0 9.7e-22 77.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXL43638.1 - 2.1e-06 27.3 0.0 1.1e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KXL43638.1 - 0.0042 17.0 0.0 0.012 15.6 0.0 1.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXL43638.1 - 0.16 11.6 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Complex1_LYR_2 PF13233.6 KXL43639.1 - 6.6e-07 30.0 0.7 1.1e-06 29.3 0.7 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KXL43639.1 - 1.6e-06 28.0 0.4 3.1e-06 27.1 0.4 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) FAS_I_H PF18314.1 KXL43639.1 - 0.02 14.5 1.0 0.022 14.4 1.0 1.2 1 0 0 1 1 1 0 Fatty acid synthase type I helical domain IKKbetaNEMObind PF12179.8 KXL43639.1 - 0.02 14.9 0.0 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain Vps51 PF08700.11 KXL43639.1 - 0.049 13.7 0.0 0.11 12.5 0.0 1.7 1 1 0 1 1 1 0 Vps51/Vps67 RNA_pol_L_2 PF13656.6 KXL43640.1 - 6.5e-33 112.3 0.0 8.9e-33 111.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KXL43640.1 - 4.9e-12 45.1 0.0 6.9e-12 44.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain IGPD PF00475.18 KXL43641.1 - 9.5e-60 201.1 0.7 1.3e-59 200.6 0.7 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase SNF2_N PF00176.23 KXL43642.1 - 2.3e-73 246.9 0.9 2.3e-73 246.9 0.9 2.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.25 KXL43642.1 - 8e-24 83.5 0.4 2.3e-23 82.1 0.4 1.8 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.31 KXL43642.1 - 2.7e-21 76.0 0.8 2.3e-18 66.5 0.0 3.9 3 1 1 4 4 4 1 Helicase conserved C-terminal domain HSA PF07529.13 KXL43642.1 - 1.4e-19 70.2 15.8 2.2e-19 69.5 13.0 3.1 2 0 0 2 2 2 1 HSA SnAC PF14619.6 KXL43642.1 - 4.7e-13 49.5 2.2 4.7e-13 49.5 2.2 3.3 2 0 0 2 2 2 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 KXL43642.1 - 8.6e-12 45.4 0.0 8.6e-12 45.4 0.0 3.2 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit QLQ PF08880.11 KXL43642.1 - 6.9e-10 38.5 1.4 6.9e-10 38.5 1.4 2.3 2 0 0 2 2 2 1 QLQ Ldh_1_N PF00056.23 KXL43643.1 - 2.8e-44 150.7 0.1 3.8e-44 150.2 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KXL43643.1 - 1.2e-43 148.9 0.0 1.7e-43 148.5 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 KXL43643.1 - 0.0012 17.9 0.0 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 KXL43643.1 - 0.0068 16.0 0.1 0.29 10.7 0.1 2.2 1 1 1 2 2 2 2 Family 4 glycosyl hydrolase DKCLD PF08068.12 KXL43644.1 - 1.4e-32 111.5 0.1 5.3e-31 106.5 0.1 2.6 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 KXL43644.1 - 4.5e-23 81.2 0.8 9.4e-23 80.1 0.8 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 KXL43644.1 - 2.1e-22 80.1 3.7 2.4e-20 73.4 0.1 3.6 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 KXL43644.1 - 3.6e-20 71.7 1.7 6.9e-20 70.8 1.7 1.5 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 KXL43644.1 - 0.016 15.4 0.0 0.04 14.2 0.0 1.6 1 0 0 1 1 1 0 UPF0113 PUA domain Med19 PF10278.9 KXL43644.1 - 0.73 9.7 11.3 2.8 7.8 11.6 1.8 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Spo12 PF05032.12 KXL43645.1 - 4.6e-11 42.4 0.7 7.3e-11 41.8 0.7 1.4 1 0 0 1 1 1 1 Spo12 family RCR PF12273.8 KXL43645.1 - 0.056 14.1 1.5 0.07 13.8 1.5 1.2 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF2236 PF09995.9 KXL43646.1 - 9e-08 32.6 0.3 1.4e-07 32.0 0.3 1.4 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF3425 PF11905.8 KXL43647.1 - 5.8e-07 29.5 1.0 1.3e-06 28.4 1.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KXL43647.1 - 0.024 14.7 8.6 0.064 13.4 8.6 1.7 1 0 0 1 1 1 0 bZIP transcription factor DUF1635 PF07795.11 KXL43647.1 - 0.047 13.5 0.2 0.087 12.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) FmiP_Thoc5 PF09766.9 KXL43647.1 - 0.13 11.5 5.0 0.2 10.9 5.0 1.2 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 Tocopherol_cycl PF14249.6 KXL43648.1 - 0.057 12.5 0.1 0.095 11.8 0.1 1.3 1 0 0 1 1 1 0 Tocopherol cyclase UQ_con PF00179.26 KXL43649.1 - 3.4e-36 124.0 0.0 4.7e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Inv-AAD PF18785.1 KXL43651.1 - 2.4e-46 156.8 0.0 3.6e-46 156.2 0.0 1.3 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 KXL43651.1 - 2.4e-13 49.8 0.0 4.1e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXL43651.1 - 0.074 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 MafB19-like deaminase Striatin PF08232.12 KXL43652.1 - 3.8e-43 147.8 7.1 3.8e-43 147.8 7.1 2.0 2 1 0 2 2 2 1 Striatin family WD40 PF00400.32 KXL43652.1 - 4.3e-22 78.0 12.6 0.00094 19.9 0.0 8.1 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL43652.1 - 5.2e-06 26.7 0.0 0.33 11.3 0.1 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain UNC119_bdg PF15435.6 KXL43652.1 - 0.083 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 UNC119-binding protein C5orf30 homologue Sacchrp_dh_C PF16653.5 KXL43653.1 - 1.5e-92 310.4 0.0 2.8e-92 309.6 0.0 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KXL43653.1 - 1.1e-22 80.7 1.1 1.5e-22 80.2 1.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KXL43653.1 - 1.6e-06 28.2 0.2 3.1e-06 27.3 0.2 1.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 KXL43653.1 - 0.00032 20.3 0.1 0.0015 18.1 0.1 2.2 1 1 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 KXL43653.1 - 0.015 15.7 0.3 0.032 14.6 0.3 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF2325 PF10087.9 KXL43653.1 - 0.02 15.0 0.2 0.039 14.1 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) AlaDh_PNT_C PF01262.21 KXL43653.1 - 0.046 13.0 0.2 0.068 12.5 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GFO_IDH_MocA PF01408.22 KXL43653.1 - 0.088 13.6 0.1 0.17 12.7 0.1 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_10 PF13460.6 KXL43653.1 - 0.14 12.1 0.3 0.21 11.4 0.3 1.3 1 0 0 1 1 1 0 NAD(P)H-binding TrkA_N PF02254.18 KXL43653.1 - 0.15 12.4 0.5 0.42 10.9 0.8 1.6 2 0 0 2 2 2 0 TrkA-N domain RFX_DNA_binding PF02257.15 KXL43654.1 - 1.7e-28 99.0 0.2 7.1e-28 97.1 0.0 2.1 2 0 0 2 2 2 1 RFX DNA-binding domain TFIIA PF03153.13 KXL43654.1 - 2.9 7.8 38.1 0.29 11.1 22.7 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TB2_DP1_HVA22 PF03134.19 KXL43655.1 - 3e-27 94.4 8.0 3e-27 94.4 8.0 1.5 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Swi5 PF07061.11 KXL43656.1 - 1.1e-22 79.9 0.1 2.4e-22 78.8 0.1 1.6 1 1 0 1 1 1 1 Swi5 DivIC PF04977.15 KXL43656.1 - 0.14 11.9 0.0 0.6 9.9 0.0 1.8 2 0 0 2 2 2 0 Septum formation initiator Ytp1 PF10355.9 KXL43657.1 - 3e-72 243.2 12.7 1e-71 241.4 12.7 1.8 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KXL43657.1 - 1.9e-27 95.1 1.0 1.9e-27 95.1 1.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.16 KXL43657.1 - 0.00062 19.9 6.5 0.00062 19.9 6.5 3.7 5 0 0 5 5 5 1 Eukaryotic cytochrome b561 DUF420 PF04238.12 KXL43657.1 - 1.4 9.2 11.3 0.41 10.9 2.4 3.6 3 2 0 3 3 3 0 Protein of unknown function (DUF420) Sec8_exocyst PF04048.14 KXL43658.1 - 3.6e-39 133.9 0.1 1.2e-38 132.2 0.1 1.9 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 KXL43658.1 - 2.9e-07 30.1 0.2 5.1e-07 29.3 0.2 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 KXL43658.1 - 0.038 12.6 0.4 0.084 11.4 0.1 1.6 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 TPR_2 PF07719.17 KXL43659.1 - 2.2e-19 68.0 30.7 0.00025 20.9 0.1 12.8 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_1 PF00515.28 KXL43659.1 - 7.6e-18 63.5 17.1 0.0011 18.6 0.0 11.2 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_19 PF14559.6 KXL43659.1 - 1.2e-15 57.7 32.5 7.4e-05 23.2 0.0 10.5 9 2 2 11 11 11 5 Tetratricopeptide repeat TPR_16 PF13432.6 KXL43659.1 - 9e-13 48.7 39.2 3.5e-05 24.3 0.5 9.0 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 KXL43659.1 - 6.9e-11 41.5 16.0 0.099 12.9 0.0 11.1 12 0 0 12 12 11 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXL43659.1 - 1.9e-09 36.9 25.9 0.0033 17.4 0.0 9.9 11 1 0 11 11 11 4 Tetratricopeptide repeat TPR_12 PF13424.6 KXL43659.1 - 1.7e-08 34.6 39.0 0.013 15.8 0.3 9.6 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXL43659.1 - 2.2e-08 34.2 49.8 0.013 16.3 0.2 14.6 12 5 5 17 17 15 3 Tetratricopeptide repeat TPR_10 PF13374.6 KXL43659.1 - 1.1e-07 31.5 10.3 0.067 13.1 0.0 8.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXL43659.1 - 3.7e-07 30.4 32.1 0.00037 21.0 0.1 10.4 13 0 0 13 13 12 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KXL43659.1 - 8.2e-06 26.0 9.0 0.069 13.4 0.0 4.6 4 0 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KXL43659.1 - 0.0011 19.2 10.4 13 6.5 0.1 9.8 12 1 1 13 13 11 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXL43659.1 - 0.0032 17.5 0.1 39 4.4 0.0 4.6 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat DUF4383 PF14325.6 KXL43659.1 - 0.1 12.9 0.3 0.56 10.5 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4383) TPR_11 PF13414.6 KXL43659.1 - 0.26 11.0 0.0 0.26 11.0 0.0 8.5 8 2 2 10 10 10 0 TPR repeat Methyltr_RsmB-F PF01189.17 KXL43662.1 - 2.3e-75 252.7 0.0 4e-75 251.9 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KXL43662.1 - 3.5e-08 33.8 0.0 1.4e-07 31.9 0.0 2.1 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Methyltransf_31 PF13847.6 KXL43662.1 - 0.021 14.7 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 KXL43662.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Sulfatase PF00884.23 KXL43663.1 - 1.4e-73 248.0 0.0 2.5e-73 247.2 0.0 1.4 1 1 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 KXL43663.1 - 0.01 16.5 0.0 0.41 11.4 0.0 2.5 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF4976 PF16347.5 KXL43663.1 - 0.012 15.8 0.1 0.055 13.7 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 KXL43663.1 - 0.047 13.3 0.0 5.1 6.6 0.0 2.2 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KXL43663.1 - 0.1 11.2 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Sugar_tr PF00083.24 KXL43664.1 - 1.6e-106 356.9 21.5 1.9e-106 356.6 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL43664.1 - 1.6e-15 56.9 23.0 1.6e-15 56.9 23.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily ATP-synt_Z PF16594.5 KXL43664.1 - 0.017 14.6 0.1 0.07 12.6 0.1 2.1 1 0 0 1 1 1 0 Putative AtpZ or ATP-synthase-associated DUF350 PF03994.14 KXL43664.1 - 0.23 11.6 0.1 0.23 11.6 0.1 3.5 3 0 0 3 3 3 0 Domain of Unknown Function (DUF350) Ferric_reduct PF01794.19 KXL43664.1 - 1.3 9.2 7.5 0.37 10.9 3.4 2.2 2 0 0 2 2 2 0 Ferric reductase like transmembrane component DUF4179 PF13786.6 KXL43664.1 - 4.8 7.7 6.7 6 7.4 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) tRNA-synt_2b PF00587.25 KXL43667.1 - 8.8e-37 126.8 0.0 1.6e-36 125.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KXL43667.1 - 5.8e-13 49.0 7.2 5.8e-13 49.0 7.2 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain IES5 PF17335.2 KXL43667.1 - 0.021 15.1 0.8 0.082 13.2 0.3 2.2 2 0 0 2 2 2 0 Ino80 complex subunit 5 NuA4 PF09340.10 KXL43667.1 - 0.66 9.9 4.0 0.45 10.4 1.4 2.1 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 Brix PF04427.18 KXL43668.1 - 1.9e-38 132.5 0.0 2.5e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Brix domain SNF2_N PF00176.23 KXL43669.1 - 4e-65 219.8 1.5 9.9e-65 218.5 1.5 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 KXL43669.1 - 3.6e-45 153.6 17.4 3.6e-45 153.6 17.4 4.6 5 1 0 5 5 5 1 DNA-binding domain Helicase_C PF00271.31 KXL43669.1 - 1.1e-19 70.7 0.0 2.9e-19 69.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL43669.1 - 1.5e-05 25.1 0.7 5.9e-05 23.1 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KXL43669.1 - 0.046 12.9 3.7 0.077 12.2 0.0 3.0 3 0 0 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 baeRF_family12 PF18856.1 KXL43669.1 - 0.063 13.9 0.1 0.063 13.9 0.1 4.5 5 0 0 5 5 5 0 Bacterial archaeo-eukaryotic release factor family 12 CDP-OH_P_transf PF01066.21 KXL43670.1 - 9.1e-16 58.4 0.3 9.1e-16 58.4 0.3 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase YqzL PF14006.6 KXL43671.1 - 0.0096 16.3 0.0 0.017 15.4 0.0 1.3 1 0 0 1 1 1 1 YqzL-like protein Gti1_Pac2 PF09729.9 KXL43672.1 - 2e-62 210.5 0.0 2.4e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 Gti1/Pac2 family MIF4G_like PF09088.11 KXL43676.1 - 1.5e-81 272.8 0.5 2.3e-81 272.2 0.5 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 KXL43676.1 - 7e-65 219.2 0.2 9.9e-65 218.7 0.2 1.2 1 0 0 1 1 1 1 MIF4G like G10 PF01125.17 KXL43677.1 - 5.1e-68 227.4 6.8 5.5e-68 227.3 6.8 1.0 1 0 0 1 1 1 1 G10 protein Auto_anti-p27 PF06677.12 KXL43677.1 - 0.027 14.6 1.6 0.027 14.6 1.6 1.8 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Sad1_UNC PF07738.13 KXL43678.1 - 6e-33 113.7 0.0 1.2e-32 112.6 0.0 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Auxin_repressed PF05564.12 KXL43678.1 - 0.27 12.0 0.1 0.27 12.0 0.1 3.7 4 0 0 4 4 4 0 Dormancy/auxin associated protein GIDA PF01134.22 KXL43679.1 - 2.2e-158 527.4 0.0 2.7e-158 527.2 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 KXL43679.1 - 5.1e-70 235.9 0.0 7.1e-70 235.5 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain Pyr_redox_2 PF07992.14 KXL43679.1 - 4.7e-06 26.0 0.8 1.5e-05 24.4 0.4 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXL43679.1 - 1.1e-05 25.0 0.3 1.9e-05 24.2 0.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXL43679.1 - 0.0005 19.3 3.4 0.00065 18.9 1.4 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KXL43679.1 - 0.0017 18.8 0.3 0.0048 17.4 0.3 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXL43679.1 - 0.0021 17.4 1.0 0.0044 16.4 1.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KXL43679.1 - 0.018 14.1 0.0 0.032 13.3 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 KXL43679.1 - 0.023 14.3 0.8 4.4 6.8 0.0 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXL43679.1 - 0.027 13.7 0.2 0.087 12.1 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXL43679.1 - 0.06 12.0 3.3 0.36 9.5 0.3 2.7 3 0 0 3 3 3 0 HI0933-like protein DEAD PF00270.29 KXL43681.1 - 1.6e-47 161.5 0.0 1.3e-46 158.5 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXL43681.1 - 7.4e-29 100.3 0.0 5.4e-28 97.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL43681.1 - 0.00032 20.8 0.0 0.00077 19.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PRAI PF00697.22 KXL43681.1 - 0.0049 16.7 0.0 0.0093 15.8 0.0 1.4 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DUF3334 PF11813.8 KXL43681.1 - 0.086 12.6 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) Rad60-SLD PF11976.8 KXL43682.1 - 7.4e-05 22.5 0.0 0.44 10.4 0.0 3.5 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KXL43682.1 - 0.0012 18.5 0.0 0.33 10.7 0.0 3.7 4 0 0 4 4 4 1 Ubiquitin family MOSC PF03473.17 KXL43684.1 - 7e-33 113.4 0.0 1.3e-32 112.6 0.0 1.5 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KXL43684.1 - 2.1e-23 82.5 0.0 4e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.19 KXL43684.1 - 2.7e-23 82.5 0.0 6.1e-23 81.4 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V MCM PF00493.23 KXL43685.1 - 8.5e-104 345.5 0.0 1.3e-103 344.9 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KXL43685.1 - 3.6e-32 110.9 0.4 6e-32 110.1 0.4 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KXL43685.1 - 8.2e-19 67.8 0.7 2e-18 66.6 0.3 2.0 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 KXL43685.1 - 9.2e-17 61.5 0.1 2.4e-16 60.2 0.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KXL43685.1 - 2.1e-07 30.5 0.0 1.5e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KXL43685.1 - 3.2e-06 27.2 0.0 7.8e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 KXL43685.1 - 0.00029 20.6 0.1 0.00099 18.9 0.1 1.9 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 KXL43685.1 - 0.01 15.7 0.1 0.035 14.0 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 KXL43685.1 - 0.077 13.6 0.4 0.34 11.6 0.2 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal SR-25 PF10500.9 KXL43686.1 - 0.0075 15.9 3.5 0.0075 15.9 3.5 1.7 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein bZIP_2 PF07716.15 KXL43686.1 - 0.081 13.0 14.3 0.15 12.2 14.3 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Ribonuc_2-5A PF06479.12 KXL43688.1 - 1.1e-41 142.0 0.0 3.3e-41 140.4 0.0 1.9 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase PF00069.25 KXL43688.1 - 1.1e-39 136.4 0.0 4.3e-38 131.2 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL43688.1 - 1.4e-20 73.7 0.0 3.9e-20 72.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.21 KXL43688.1 - 5e-07 29.4 0.9 0.055 13.4 0.0 3.5 4 0 0 4 4 4 2 PQQ enzyme repeat Pkinase_fungal PF17667.1 KXL43688.1 - 0.00047 19.1 0.0 0.0022 16.8 0.0 1.9 1 1 1 2 2 2 1 Fungal protein kinase PQQ_2 PF13360.6 KXL43688.1 - 0.0044 16.6 0.1 0.13 11.8 0.1 2.5 1 1 1 2 2 2 1 PQQ-like domain APH PF01636.23 KXL43688.1 - 0.008 16.1 4.1 0.069 13.1 0.6 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family PepSY PF03413.19 KXL43688.1 - 0.032 14.8 0.0 0.087 13.4 0.0 1.8 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain YrbL-PhoP_reg PF10707.9 KXL43688.1 - 0.04 13.4 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.14 KXL43688.1 - 0.11 11.8 0.1 0.25 10.7 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Bax1-I PF01027.20 KXL43689.1 - 1.5e-51 175.2 30.9 1.7e-51 175.0 30.9 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Spore_YhaL PF14147.6 KXL43689.1 - 0.13 12.0 0.3 0.53 10.0 0.3 2.0 1 0 0 1 1 1 0 Sporulation protein YhaL DUF3754 PF12576.8 KXL43689.1 - 1.2 9.1 4.1 0.56 10.2 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) Polyketide_cyc PF03364.20 KXL43690.1 - 2.4e-14 53.6 0.0 4.9e-14 52.7 0.0 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 KXL43690.1 - 0.0002 21.6 0.1 0.0039 17.5 0.1 2.2 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Methyltransf_12 PF08242.12 KXL43691.1 - 9.3e-17 61.6 0.0 2.7e-16 60.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL43691.1 - 2.1e-15 57.2 0.0 3.9e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXL43691.1 - 3.3e-13 49.8 0.0 4.9e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL43691.1 - 3.5e-12 46.8 0.0 7.5e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL43691.1 - 1.8e-08 34.3 0.0 3.1e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KXL43691.1 - 3.5e-07 31.2 0.0 7.1e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXL43691.1 - 8.8e-05 21.9 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KXL43691.1 - 0.0018 18.0 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase NNMT_PNMT_TEMT PF01234.17 KXL43691.1 - 0.0019 17.5 0.0 0.43 9.7 0.0 2.4 1 1 0 2 2 2 2 NNMT/PNMT/TEMT family MTS PF05175.14 KXL43691.1 - 0.0019 17.8 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KXL43691.1 - 0.0097 15.9 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXL43691.1 - 0.051 12.9 0.0 0.088 12.1 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase TPMT PF05724.11 KXL43691.1 - 0.057 13.1 0.1 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Cnl2_NKP2 PF09447.10 KXL43691.1 - 0.14 12.4 0.2 1.9 8.7 0.0 2.4 2 0 0 2 2 2 0 Cnl2/NKP2 family protein E1-E2_ATPase PF00122.20 KXL43692.1 - 1.6e-53 180.9 2.2 1.1e-51 174.9 0.5 2.9 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KXL43692.1 - 3.9e-48 163.6 4.6 3.9e-48 163.6 4.6 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KXL43692.1 - 6.8e-22 78.8 2.0 4.6e-21 76.1 2.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXL43692.1 - 5.7e-21 74.4 0.0 1.1e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KXL43692.1 - 2.2e-18 65.7 0.0 7.3e-18 64.0 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXL43692.1 - 3.2e-08 33.6 1.4 1.6e-06 28.0 0.9 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXL43692.1 - 1.2e-06 29.1 0.0 4.5e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Arrestin_N PF00339.29 KXL43693.1 - 1.7e-18 67.1 0.0 9.3e-18 64.7 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KXL43693.1 - 2.4e-09 37.7 0.0 0.00037 21.0 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Response_reg PF00072.24 KXL43694.1 - 2.3e-20 72.8 0.6 9.5e-15 54.7 0.0 3.0 3 0 0 3 3 3 2 Response regulator receiver domain HATPase_c PF02518.26 KXL43694.1 - 2.2e-18 66.8 0.0 5.5e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KXL43694.1 - 1.2e-05 25.3 0.0 2.7e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain RIG-I_C PF18119.1 KXL43694.1 - 0.11 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 RIG-I receptor C-terminal domain HATPase_c_2 PF13581.6 KXL43694.1 - 0.14 12.2 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain FmiP_Thoc5 PF09766.9 KXL43695.1 - 2.2e-28 99.6 8.3 2.9e-28 99.2 8.3 1.2 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 DUF4201 PF13870.6 KXL43695.1 - 0.0084 15.9 8.9 0.4 10.4 1.4 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4201) DUF4140 PF13600.6 KXL43695.1 - 0.078 13.4 10.8 0.5 10.8 1.6 2.8 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) PRKG1_interact PF15898.5 KXL43695.1 - 0.12 13.3 5.0 0.13 13.2 3.3 2.0 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain APG6_N PF17675.1 KXL43695.1 - 0.21 12.1 20.1 0.7 10.4 3.8 2.3 2 1 0 2 2 2 0 Apg6 coiled-coil region DivIC PF04977.15 KXL43695.1 - 0.3 10.9 9.4 3.4 7.5 0.7 2.6 2 0 0 2 2 2 0 Septum formation initiator Seryl_tRNA_N PF02403.22 KXL43695.1 - 0.37 11.0 4.3 12 6.2 0.1 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Mod_r PF07200.13 KXL43695.1 - 0.68 10.0 9.6 1.2 9.2 2.8 2.3 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF4726 PF15855.5 KXL43695.1 - 0.77 10.0 8.0 2.5 8.4 0.3 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4726) TMF_TATA_bd PF12325.8 KXL43695.1 - 3.6 7.8 12.0 10 6.4 5.7 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4200 PF13863.6 KXL43695.1 - 5.9 7.3 13.8 2.6 8.5 1.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) CHAT PF12770.7 KXL43696.1 - 7.4e-33 114.2 0.6 2.4e-31 109.3 0.6 2.7 1 1 0 1 1 1 1 CHAT domain ADK PF00406.22 KXL43699.1 - 1.9e-44 151.4 0.0 2.5e-44 151.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KXL43699.1 - 7.2e-36 123.6 0.0 1e-35 123.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXL43699.1 - 2.8e-10 40.9 0.0 3.9e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXL43699.1 - 6.3e-06 26.4 0.0 1.6e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KXL43699.1 - 4.4e-05 23.3 0.0 0.12 12.0 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase Ploopntkinase3 PF18751.1 KXL43699.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Pro_isomerase PF00160.21 KXL43700.1 - 1.2e-49 168.7 0.1 2.2e-49 167.8 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KXL43700.1 - 8.2e-12 45.5 1.8 0.0019 19.0 0.0 5.0 4 0 0 4 4 4 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KXL43700.1 - 0.00084 18.4 0.7 0.36 9.7 0.0 3.2 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KXL43700.1 - 0.0041 17.4 0.0 0.5 10.7 0.0 3.5 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain BofC_C PF08955.10 KXL43700.1 - 0.067 13.2 0.0 14 5.8 0.0 2.6 2 0 0 2 2 2 0 BofC C-terminal domain R3H PF01424.22 KXL43701.1 - 1.7e-15 56.8 0.1 4.4e-15 55.4 0.1 1.7 2 0 0 2 2 2 1 R3H domain zf-NF-X1 PF01422.17 KXL43701.1 - 5.6e-06 26.3 55.4 0.00014 21.8 12.4 14.3 18 2 0 18 18 18 7 NF-X1 type zinc finger LPP20 PF02169.16 KXL43701.1 - 0.16 12.3 0.0 0.42 11.0 0.0 1.6 1 0 0 1 1 1 0 LPP20 lipoprotein Stm1_N PF09598.10 KXL43701.1 - 7.4 7.5 6.9 27 5.7 6.9 1.9 1 0 0 1 1 1 0 Stm1 RNA_pol_L_2 PF13656.6 KXL43703.1 - 1.4e-24 85.6 0.0 1.9e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KXL43703.1 - 1.1e-08 34.4 0.0 1.8e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain NMO PF03060.15 KXL43704.1 - 2.5e-25 89.6 5.9 4.5e-19 69.0 2.6 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 KXL43704.1 - 1.9e-06 27.2 0.3 2.8e-06 26.6 0.3 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KXL43704.1 - 3.7e-06 26.2 0.4 8.2e-05 21.8 0.4 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KXL43704.1 - 0.00042 19.6 0.3 0.00064 19.0 0.3 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase RabGAP-TBC PF00566.18 KXL43705.1 - 1.6e-33 116.2 0.0 3.3e-33 115.2 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBE2 PF17076.5 KXL43705.1 - 5.1e-06 25.0 4.2 7.4e-06 24.5 4.2 1.1 1 0 0 1 1 1 1 SBE2, cell-wall formation Questin_oxidase PF14027.6 KXL43706.1 - 2.1e-98 330.0 3.7 2.7e-98 329.7 3.7 1.1 1 0 0 1 1 1 1 Questin oxidase-like DUF3669 PF12417.8 KXL43706.1 - 0.19 12.0 0.7 0.54 10.5 0.1 2.2 2 0 0 2 2 2 0 Zinc finger protein MFS_1 PF07690.16 KXL43707.1 - 3.1e-35 121.7 33.0 4.6e-35 121.2 33.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL43707.1 - 5.8e-13 48.5 6.2 5.8e-13 48.5 6.2 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter FAD_binding_3 PF01494.19 KXL43708.1 - 8.7e-25 87.7 0.0 2.3e-24 86.3 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXL43708.1 - 3.1e-10 40.2 5.4 3.1e-05 23.7 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXL43708.1 - 3.1e-08 33.2 0.0 0.005 16.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXL43708.1 - 9.2e-06 24.6 0.8 6.9e-05 21.7 0.8 2.0 1 1 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.14 KXL43708.1 - 3.7e-05 22.8 1.3 0.0015 17.4 0.3 2.2 1 1 1 2 2 2 1 Tryptophan halogenase FAD_binding_2 PF00890.24 KXL43708.1 - 5.1e-05 22.5 3.6 8.6e-05 21.8 3.6 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXL43708.1 - 6.5e-05 23.1 1.6 0.00043 20.5 1.7 2.3 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KXL43708.1 - 0.00035 20.0 0.4 0.003 16.9 0.0 2.5 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase GIDA PF01134.22 KXL43708.1 - 0.00071 18.8 0.0 0.00081 18.6 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KXL43708.1 - 0.00096 18.6 0.1 0.0012 18.3 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXL43708.1 - 0.0013 19.2 1.0 1.4 9.5 0.9 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KXL43708.1 - 0.0035 16.4 0.0 0.12 11.4 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Thi4 PF01946.17 KXL43708.1 - 0.069 12.4 0.6 0.12 11.6 0.6 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KXL43708.1 - 0.075 12.1 2.3 1.6 7.7 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KXL43708.1 - 0.37 10.0 0.7 1.1 8.4 1.2 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3500 PF12006.8 KXL43709.1 - 1.1e-96 323.9 0.0 1.3e-96 323.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) LTXXQ PF07813.12 KXL43709.1 - 0.13 13.0 0.1 0.3 11.8 0.1 1.6 1 0 0 1 1 1 0 LTXXQ motif family protein zf-LYAR PF08790.11 KXL43710.1 - 1.3e-14 53.8 3.4 1.3e-14 53.8 3.4 3.3 3 0 0 3 3 3 1 LYAR-type C2HC zinc finger Apt1 PF10351.9 KXL43710.1 - 7.3 5.3 15.4 0.41 9.5 10.1 1.5 2 0 0 2 2 2 0 Golgi-body localisation protein domain Fungal_trans_2 PF11951.8 KXL43711.1 - 9.6e-12 44.4 0.1 9.6e-12 44.4 0.1 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain SURF6 PF04935.12 KXL43711.1 - 0.45 10.3 5.3 0.64 9.8 5.3 1.2 1 0 0 1 1 1 0 Surfeit locus protein 6 Ribosomal_S28e PF01200.18 KXL43713.1 - 1.9e-31 107.8 1.7 2.1e-31 107.7 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e GST_C PF00043.25 KXL43714.1 - 6.7e-08 32.6 0.0 1e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXL43714.1 - 1e-06 28.6 0.0 1.7e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KXL43714.1 - 0.0018 18.8 0.0 0.0033 18.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXL43714.1 - 0.0072 16.5 0.0 0.028 14.6 0.0 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KXL43714.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain hDGE_amylase PF14701.6 KXL43716.1 - 1.7e-176 587.7 0.0 2.2e-176 587.3 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 KXL43716.1 - 7.5e-117 390.5 0.1 1.2e-116 389.8 0.1 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 KXL43716.1 - 5.4e-84 281.8 0.0 8.7e-84 281.1 0.0 1.3 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 KXL43716.1 - 2.7e-29 101.1 0.1 6.8e-29 99.9 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 KXL43716.1 - 0.001 18.7 0.1 0.002 17.7 0.1 1.4 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Acetyltransf_10 PF13673.7 KXL43717.1 - 8.2e-09 35.5 0.0 1.1e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXL43717.1 - 7.1e-07 29.6 0.0 8.7e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXL43717.1 - 9.4e-07 29.0 0.1 1.2e-06 28.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXL43717.1 - 1.6e-06 28.4 0.0 2e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KXL43717.1 - 0.00027 20.8 0.0 0.00044 20.2 0.0 1.4 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_13 PF13880.6 KXL43717.1 - 0.049 13.6 0.0 0.068 13.2 0.0 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase PanZ PF12568.8 KXL43717.1 - 0.058 13.1 0.0 0.07 12.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 KXL43717.1 - 0.094 12.9 0.0 0.15 12.2 0.0 1.4 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase APG5 PF04106.12 KXL43718.1 - 5.7e-65 219.1 0.0 7.1e-65 218.8 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 HhH-GPD PF00730.25 KXL43719.1 - 2.1e-08 34.6 0.0 2.3e-08 34.4 0.0 1.3 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein WD40 PF00400.32 KXL43720.1 - 1.7e-53 177.4 17.7 0.00013 22.6 0.0 13.6 13 2 0 13 13 13 8 WD domain, G-beta repeat Utp13 PF08625.11 KXL43720.1 - 5e-47 159.4 0.2 8.8e-47 158.6 0.2 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 KXL43720.1 - 3.4e-14 52.9 1.1 1.9 8.9 0.0 8.9 7 2 1 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXL43720.1 - 5e-08 32.1 8.4 0.051 12.2 0.6 6.2 5 2 1 8 8 8 3 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KXL43720.1 - 0.027 13.4 2.8 0.15 11.0 0.1 2.9 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain DNA_pol_A_exoN PF18305.1 KXL43720.1 - 0.088 13.1 0.2 0.34 11.2 0.2 2.0 1 0 0 1 1 1 0 3' to 5' exonuclease C-terminal domain Ge1_WD40 PF16529.5 KXL43720.1 - 0.18 10.7 4.2 17 4.3 0.0 5.2 5 1 2 7 7 7 0 WD40 region of Ge1, enhancer of mRNA-decapping protein cobW PF02492.19 KXL43721.1 - 1.9e-36 125.3 0.1 2.7e-36 124.8 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 KXL43721.1 - 1.5e-05 24.9 0.0 3.8e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.22 KXL43721.1 - 0.00047 19.9 0.0 0.00093 18.9 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_22 PF13401.6 KXL43721.1 - 0.0027 18.0 0.3 0.011 16.0 0.1 2.2 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KXL43721.1 - 0.012 14.8 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CbiA PF01656.23 KXL43721.1 - 0.016 15.3 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Viral_helicase1 PF01443.18 KXL43721.1 - 0.018 14.8 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 KXL43721.1 - 0.02 14.6 0.1 0.081 12.7 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain TrwB_AAD_bind PF10412.9 KXL43721.1 - 0.029 13.3 0.0 0.053 12.4 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.6 KXL43721.1 - 0.031 14.8 3.2 0.052 14.0 2.4 1.7 2 0 0 2 2 2 0 AAA domain DUF463 PF04317.12 KXL43721.1 - 0.034 13.1 0.0 0.054 12.4 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 AAA_16 PF13191.6 KXL43721.1 - 0.043 14.2 0.0 0.074 13.4 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 KXL43721.1 - 0.068 13.1 0.1 0.18 11.7 0.1 1.7 1 0 0 1 1 1 0 NTPase T2SSE PF00437.20 KXL43721.1 - 0.12 11.4 0.1 0.25 10.4 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.6 KXL43721.1 - 0.14 12.2 0.1 0.27 11.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KXL43721.1 - 0.14 12.1 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_11 PF13086.6 KXL43721.1 - 0.24 11.1 1.0 3.3 7.4 0.1 2.3 1 1 1 2 2 2 0 AAA domain Ribosomal_S13 PF00416.22 KXL43722.1 - 3e-20 72.9 1.0 5.5e-18 65.6 1.0 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 KXL43722.1 - 0.006 15.4 0.0 0.0068 15.2 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Proteasome PF00227.26 KXL43723.1 - 7.5e-36 123.4 0.0 8.9e-36 123.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Peptidase_M16_C PF05193.21 KXL43725.1 - 6.7e-22 78.4 0.0 1.8e-17 63.9 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KXL43725.1 - 2e-06 27.8 0.0 4.3e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) CobT PF06213.12 KXL43725.1 - 0.1 11.9 6.0 0.21 11.0 6.0 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Astro_capsid_p PF12226.8 KXL43725.1 - 5.5 6.0 10.6 8.9 5.4 10.6 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Pro_isomerase PF00160.21 KXL43727.1 - 8.3e-51 172.4 0.2 1e-50 172.1 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DEAD PF00270.29 KXL43728.1 - 3.8e-49 166.8 0.0 9.3e-49 165.6 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXL43728.1 - 4.2e-32 110.8 0.0 9.2e-32 109.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL43728.1 - 0.0059 16.6 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KXL43728.1 - 0.089 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit UTP25 PF06862.12 KXL43728.1 - 0.33 9.7 0.0 0.84 8.3 0.0 1.6 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 GSH_synthase PF03199.15 KXL43729.1 - 0.053 14.0 0.1 0.078 13.4 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic glutathione synthase Zn_clus PF00172.18 KXL43730.1 - 4e-06 26.9 21.7 5.5e-06 26.4 21.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SO_alpha_A3 PF17806.1 KXL43731.1 - 0.02 15.2 0.1 0.023 15.0 0.1 1.1 1 0 0 1 1 1 0 Sarcosine oxidase A3 domain PhyH PF05721.13 KXL43732.1 - 8.6e-10 39.2 0.0 9.9e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KXL43732.1 - 0.055 12.2 0.3 4.2 6.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1479) PhyH PF05721.13 KXL43733.1 - 0.031 14.5 0.1 0.48 10.6 0.1 2.2 1 1 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) UPF0697 PF15117.6 KXL43733.1 - 0.2 11.8 0.0 0.38 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0697 Y_phosphatase PF00102.27 KXL43735.1 - 5.4e-49 166.9 0.0 9.9e-49 166.0 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KXL43735.1 - 0.0022 17.8 0.1 0.0064 16.3 0.1 1.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KXL43735.1 - 0.06 13.3 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Mrx7 PF10906.8 KXL43736.1 - 5.9e-07 29.6 0.1 2.8e-06 27.5 0.1 1.8 1 1 0 1 1 1 1 MIOREX complex component 7 DUF2277 PF10041.9 KXL43736.1 - 0.11 12.9 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2277) TauD PF02668.16 KXL43738.1 - 1.4e-33 116.8 0.1 1.9e-33 116.4 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TSSC4 PF15264.6 KXL43738.1 - 0.15 12.3 0.2 0.32 11.3 0.2 1.5 1 0 0 1 1 1 0 Tumour suppressing sub-chromosomal transferable candidate 4 MTS PF05175.14 KXL43740.1 - 0.00011 21.8 0.0 0.00025 20.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KXL43740.1 - 0.14 11.6 0.1 0.17 11.2 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Complex1_LYR_2 PF13233.6 KXL43741.1 - 1.7e-20 73.5 0.0 2.3e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KXL43741.1 - 7.5e-11 41.9 0.0 1.7e-10 40.7 0.0 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Gln-synt_C PF00120.24 KXL43743.1 - 8.2e-63 212.5 0.0 1.2e-62 212.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.14 KXL43743.1 - 9.5e-14 51.9 0.0 1.7e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase DNA_pol_A_exo1 PF01612.20 KXL43744.1 - 8.7e-39 133.0 0.2 1.6e-38 132.2 0.2 1.5 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 KXL43744.1 - 4.9e-27 94.5 0.3 1.6e-26 92.8 0.3 2.0 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.23 KXL43744.1 - 4e-13 49.2 0.0 8.9e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 HRDC domain Glyco_hyd_65N_2 PF14498.6 KXL43745.1 - 1.3e-46 159.4 0.3 2e-46 158.8 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, N-terminal domain UPF0203 PF05254.12 KXL43746.1 - 3.2e-27 94.6 2.8 3.7e-27 94.4 2.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 KXL43746.1 - 3.6e-05 24.0 1.9 7e-05 23.1 1.9 1.4 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 KXL43746.1 - 0.014 15.4 3.4 0.19 11.8 0.1 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.16 KXL43746.1 - 0.02 15.1 3.8 1.8 8.8 0.6 2.1 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein DUF5339 PF17274.2 KXL43746.1 - 0.048 14.5 2.6 0.23 12.3 0.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5339) NDUF_B7 PF05676.13 KXL43746.1 - 0.34 10.7 4.7 2.5 7.9 0.3 2.2 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Sortilin-Vps10 PF15902.5 KXL43747.1 - 5.6e-16 58.4 5.5 2.2e-06 26.8 0.0 6.2 4 3 3 8 8 8 6 Sortilin, neurotensin receptor 3, BNR_6 PF15899.5 KXL43747.1 - 5.1e-05 23.0 30.4 0.032 14.3 0.1 7.5 7 0 0 7 7 7 5 BNR-Asp box repeat BNR_2 PF13088.6 KXL43747.1 - 0.0051 16.2 8.1 0.83 8.9 0.1 4.8 3 2 1 5 5 5 2 BNR repeat-like domain PSII_BNR PF14870.6 KXL43747.1 - 0.016 14.5 3.4 0.93 8.7 0.3 4.3 3 2 0 3 3 3 0 Photosynthesis system II assembly factor YCF48 BNR PF02012.20 KXL43747.1 - 0.026 14.5 48.5 3.1 8.2 0.4 9.4 9 0 0 9 9 9 0 BNR/Asp-box repeat DUF1479 PF07350.12 KXL43748.1 - 0.076 11.8 0.0 0.076 11.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Sugar_tr PF00083.24 KXL43749.1 - 3.1e-21 75.8 5.8 3.5e-21 75.6 5.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL43749.1 - 6.3e-09 35.2 3.2 7.3e-09 35.0 3.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Cupin_2 PF07883.11 KXL43750.1 - 1.3e-12 47.3 0.1 2.4e-12 46.4 0.1 1.5 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.19 KXL43750.1 - 3.8e-05 23.6 0.0 6.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain DMSP_lyase PF16867.5 KXL43750.1 - 0.00096 18.8 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 Dimethlysulfonioproprionate lyase MannoseP_isomer PF01050.18 KXL43750.1 - 0.019 14.9 0.0 0.026 14.4 0.0 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Cupin_1 PF00190.22 KXL43750.1 - 0.02 14.5 0.0 0.038 13.6 0.0 1.4 1 1 0 1 1 1 0 Cupin Auxin_BP PF02041.16 KXL43750.1 - 0.033 13.8 0.0 0.11 12.1 0.0 1.7 1 1 0 1 1 1 0 Auxin binding protein Cupin_3 PF05899.12 KXL43750.1 - 0.061 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_6 PF12852.7 KXL43750.1 - 0.066 12.9 0.0 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 Cupin CENP-C_C PF11699.8 KXL43750.1 - 0.1 12.8 0.0 0.17 12.1 0.0 1.5 1 1 0 1 1 1 0 Mif2/CENP-C like UPF0231 PF06062.11 KXL43751.1 - 0.037 14.3 0.0 0.044 14.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0231) Poxvirus_B22R PF04395.12 KXL43751.1 - 0.059 12.9 0.0 0.068 12.7 0.0 1.0 1 0 0 1 1 1 0 Poxvirus B22R protein TGF_beta_GS PF08515.12 KXL43751.1 - 0.14 11.7 0.8 0.25 10.9 0.8 1.4 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif RTP1_C2 PF10304.9 KXL43752.1 - 0.087 12.5 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 HTH_psq PF05225.16 KXL43753.1 - 0.00049 19.8 0.1 0.00097 18.8 0.0 1.5 2 0 0 2 2 2 1 helix-turn-helix, Psq domain Tannase PF07519.11 KXL43754.1 - 2.6e-15 56.3 0.0 2.9e-15 56.1 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Sugar_tr PF00083.24 KXL43755.1 - 2.2e-56 191.6 13.9 2.5e-56 191.4 13.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter adh_short PF00106.25 KXL43760.1 - 6.5e-31 107.3 0.0 1e-30 106.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL43760.1 - 2e-27 96.3 0.0 2.8e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL43760.1 - 0.00031 20.7 0.6 0.0065 16.4 0.2 2.6 2 1 0 2 2 2 1 KR domain VCBS PF13517.6 KXL43760.1 - 0.047 14.3 0.0 0.13 12.9 0.0 1.8 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Epimerase PF01370.21 KXL43760.1 - 0.16 11.4 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_8 PF13450.6 KXL43761.1 - 1.8e-12 47.3 0.0 5e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 KXL43761.1 - 4.1e-12 45.3 0.1 2.7e-11 42.6 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 KXL43761.1 - 1.9e-05 24.7 0.0 4.9e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KXL43761.1 - 0.00048 19.4 0.0 2.5 7.1 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KXL43761.1 - 0.002 17.4 0.0 0.016 14.4 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXL43761.1 - 0.0058 15.9 0.0 0.43 9.8 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KXL43761.1 - 0.026 13.9 0.0 0.064 12.6 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 KXL43761.1 - 0.047 13.3 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXL43761.1 - 0.08 13.5 0.0 14 6.3 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.18 KXL43762.1 - 5.8e-20 71.4 0.0 1.2e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL43762.1 - 3.1e-05 24.0 9.6 5.5e-05 23.2 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 KXL43762.1 - 0.41 10.6 17.2 0.18 11.7 12.0 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Striatin PF08232.12 KXL43762.1 - 0.6 10.7 3.9 1.5 9.4 1.4 2.4 2 0 0 2 2 2 0 Striatin family CCDC53 PF10152.9 KXL43762.1 - 2.4 8.5 9.1 0.7 10.3 3.9 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex SPX PF03105.19 KXL43762.1 - 2.9 7.7 14.8 2.9 7.7 10.8 2.2 2 0 0 2 2 2 0 SPX domain SOG2 PF10428.9 KXL43762.1 - 3.3 6.8 17.9 1.4 8.0 9.9 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein TRI12 PF06609.13 KXL43763.1 - 3.8e-71 240.3 21.7 5e-71 239.9 21.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KXL43763.1 - 1e-30 106.9 40.8 1e-30 106.9 40.8 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL43763.1 - 4.3e-14 52.2 5.7 4.3e-14 52.2 5.7 3.2 2 1 1 3 3 3 1 Sugar (and other) transporter TNFR_16_TM PF18422.1 KXL43763.1 - 0.21 11.6 2.7 0.86 9.6 0.7 2.7 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain adh_short_C2 PF13561.6 KXL43764.1 - 6.3e-58 196.1 0.1 7.5e-58 195.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL43764.1 - 1.3e-47 161.8 0.0 1.6e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL43764.1 - 1.1e-12 48.3 0.4 1.6e-12 47.7 0.4 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXL43764.1 - 0.0015 17.7 0.1 0.0021 17.2 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Ldh_1_N PF00056.23 KXL43764.1 - 0.016 15.3 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 KXL43764.1 - 0.026 15.2 0.0 0.057 14.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain ThiF PF00899.21 KXL43764.1 - 0.11 11.8 0.8 0.27 10.5 0.3 1.9 2 1 1 3 3 3 0 ThiF family FMO-like PF00743.19 KXL43765.1 - 8.6e-12 44.2 0.0 1e-08 34.1 0.1 2.7 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXL43765.1 - 3.9e-10 39.8 0.0 9.7e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXL43765.1 - 2.3e-06 27.1 0.0 0.009 15.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXL43765.1 - 0.0027 16.9 0.2 5.1 6.1 0.0 3.7 4 1 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXL43765.1 - 0.028 13.7 0.0 0.43 9.8 0.0 2.6 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXL43765.1 - 0.059 12.6 0.0 0.16 11.1 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Fungal_TACC PF12709.7 KXL43766.1 - 7.7e-08 32.7 3.4 7.7e-08 32.7 3.4 4.7 4 1 1 5 5 5 2 Fungal Transforming acidic coiled-coil (TACC) proteins Filament PF00038.21 KXL43766.1 - 0.3 10.6 32.4 0.52 9.8 32.4 1.4 1 0 0 1 1 1 0 Intermediate filament protein DUF4407 PF14362.6 KXL43766.1 - 7 5.9 32.9 4.5 6.6 13.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Fungal_trans PF04082.18 KXL43767.1 - 1.3e-15 57.2 0.1 2.5e-15 56.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL43767.1 - 6.2e-06 26.2 11.9 1.4e-05 25.1 10.6 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 KXL43768.1 - 2e-12 47.1 4.3 0.0038 16.5 0.1 3.2 3 0 0 3 3 3 3 FAD binding domain Pyr_redox_2 PF07992.14 KXL43768.1 - 6.2e-10 38.8 0.1 0.00027 20.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXL43768.1 - 3.9e-08 33.3 0.0 0.00027 20.6 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXL43768.1 - 8.2e-07 29.2 0.5 2.3e-06 27.7 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXL43768.1 - 2.3e-06 27.0 2.9 3.8e-05 23.0 1.0 2.2 1 1 1 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KXL43768.1 - 3.3e-06 26.1 0.1 0.014 14.2 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 KXL43768.1 - 7.2e-06 25.6 0.1 1.2e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KXL43768.1 - 4.7e-05 22.7 0.0 0.12 11.5 0.0 2.0 2 0 0 2 2 2 2 Glucose inhibited division protein A Trp_halogenase PF04820.14 KXL43768.1 - 0.00028 19.9 1.5 0.0068 15.3 0.0 2.2 1 1 0 2 2 2 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 KXL43768.1 - 0.00037 19.8 0.1 0.054 12.7 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXL43768.1 - 0.0012 18.0 0.5 1.8 7.5 0.0 3.0 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox PF00070.27 KXL43768.1 - 0.003 18.1 1.1 0.8 10.3 0.6 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXL43768.1 - 0.055 12.7 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Thi4 family DUF1349 PF07081.11 KXL43769.1 - 2.9e-38 131.4 0.0 3.7e-38 131.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Brr6_like_C_C PF10104.9 KXL43770.1 - 5.1e-49 165.4 2.3 6.9e-49 165.0 2.3 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Adaptin_N PF01602.20 KXL43772.1 - 8.8e-128 427.1 8.0 1.1e-127 426.8 8.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 KXL43772.1 - 3.3e-39 133.6 0.0 7.9e-39 132.4 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 KXL43772.1 - 4.8e-17 62.3 0.0 8.7e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KXL43772.1 - 0.00041 20.4 4.0 0.065 13.3 0.0 3.0 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXL43772.1 - 0.0034 17.7 0.5 6.1 7.3 0.0 4.2 4 1 0 4 4 4 1 HEAT repeats RTP1_C1 PF10363.9 KXL43772.1 - 0.11 12.6 1.7 0.48 10.6 0.2 2.8 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 RasGEF_N_2 PF14663.6 KXL43772.1 - 0.23 11.9 2.4 12 6.4 0.1 3.1 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Metallophos PF00149.28 KXL43773.1 - 9.9e-11 42.5 1.5 9.9e-11 42.5 1.5 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 KXL43773.1 - 0.026 14.7 0.0 0.06 13.6 0.0 1.6 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain RRM_1 PF00076.22 KXL43774.1 - 4.3e-11 42.5 0.0 6.4e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXL43774.1 - 0.0015 18.1 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Profilin PF00235.19 KXL43775.1 - 3.4e-50 169.6 0.7 3.8e-50 169.4 0.7 1.0 1 0 0 1 1 1 1 Profilin GP4 PF03010.14 KXL43775.1 - 0.2 11.5 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 GP4 DUF3328 PF11807.8 KXL43776.1 - 9.6e-38 130.2 0.1 1.1e-37 130.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF5637 PF18687.1 KXL43777.1 - 0.073 13.1 0.3 0.14 12.2 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5637) PMP1_2 PF08114.11 KXL43778.1 - 0.045 13.5 0.3 1.4 8.7 0.1 2.5 2 0 0 2 2 2 0 ATPase proteolipid family FMO-like PF00743.19 KXL43779.1 - 1.1e-12 47.2 0.7 1.3e-11 43.6 0.0 2.5 2 1 1 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXL43779.1 - 6.7e-08 32.1 0.0 1.8e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXL43779.1 - 2.7e-06 26.8 0.0 0.0026 17.0 0.0 3.0 2 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXL43779.1 - 0.0013 18.9 0.0 0.0034 17.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXL43779.1 - 0.002 17.8 0.0 1.6 8.3 0.0 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXL43779.1 - 0.0046 16.2 0.0 0.19 10.9 0.0 2.8 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 KXL43779.1 - 0.04 13.4 0.0 0.41 10.1 0.0 2.4 3 0 0 3 3 3 0 Glucose dehydrogenase C-terminus Thi4 PF01946.17 KXL43779.1 - 0.12 11.6 0.0 7.1 5.8 0.0 2.4 3 0 0 3 3 3 0 Thi4 family NAD_binding_9 PF13454.6 KXL43779.1 - 0.13 12.3 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KXL43779.1 - 0.14 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein MAM33 PF02330.16 KXL43780.1 - 9.8e-55 185.8 4.8 2e-54 184.8 4.8 1.5 1 1 0 1 1 1 1 Mitochondrial glycoprotein IBN_N PF03810.19 KXL43781.1 - 4e-08 33.0 0.1 7.4e-06 25.8 0.0 3.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain RTP1_C1 PF10363.9 KXL43781.1 - 0.036 14.2 0.0 2.8 8.2 0.0 2.8 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Xpo1 PF08389.12 KXL43781.1 - 0.11 12.5 0.0 7.8 6.5 0.0 3.0 1 1 0 1 1 1 0 Exportin 1-like protein DnaJ PF00226.31 KXL43782.1 - 9.1e-21 73.8 1.5 9.1e-21 73.8 1.5 2.2 3 0 0 3 3 2 1 DnaJ domain TPR_2 PF07719.17 KXL43782.1 - 4.6e-16 57.6 21.9 0.00032 20.6 0.3 8.2 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 KXL43782.1 - 6.2e-16 57.5 16.2 0.00019 21.1 0.1 7.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 KXL43782.1 - 1.6e-11 44.2 20.8 1.5e-05 25.0 0.6 6.1 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXL43782.1 - 9.4e-10 38.5 23.6 5.7e-05 23.6 0.6 8.6 4 3 5 9 9 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXL43782.1 - 1.3e-07 31.1 5.8 4.6e-05 23.0 0.7 4.7 3 1 2 5 5 5 2 TPR repeat TPR_8 PF13181.6 KXL43782.1 - 1.3e-07 31.2 6.8 0.18 12.1 0.0 5.4 8 0 0 8 8 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 KXL43782.1 - 7.3e-07 29.1 15.1 0.0018 18.5 0.1 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXL43782.1 - 9.6e-06 26.0 23.2 0.0036 17.8 1.0 5.7 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 KXL43782.1 - 2.7e-05 24.4 23.8 0.0071 16.6 2.5 5.7 5 3 1 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXL43782.1 - 7.3e-05 23.3 27.5 0.00035 21.2 4.6 5.5 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXL43782.1 - 0.00023 20.9 13.3 1.4 9.2 0.3 6.2 5 1 1 6 6 6 2 Tetratricopeptide repeat PknG_TPR PF16918.5 KXL43782.1 - 0.0022 16.8 0.6 0.17 10.5 0.0 2.9 3 0 0 3 3 3 1 Protein kinase G tetratricopeptide repeat TPR_10 PF13374.6 KXL43782.1 - 0.0022 17.8 14.6 0.81 9.6 0.6 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXL43782.1 - 0.031 14.5 8.0 2.2 8.6 1.1 3.6 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Alkyl_sulf_dimr PF14863.6 KXL43782.1 - 0.031 14.7 8.1 4.3 7.8 0.3 3.7 4 0 0 4 4 4 0 Alkyl sulfatase dimerisation TPR_6 PF13174.6 KXL43782.1 - 0.24 12.1 26.7 0.24 12.1 0.2 7.9 10 0 0 10 10 7 0 Tetratricopeptide repeat Glyco_hydro_5_C PF18564.1 KXL43783.1 - 2.6e-20 72.7 0.0 6.7e-20 71.4 0.0 1.8 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 KXL43783.1 - 4.4e-09 36.2 1.1 4.4e-06 26.3 0.1 2.5 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) GTP_EFTU PF00009.27 KXL43784.1 - 2e-09 37.3 0.0 4.8e-08 32.8 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KXL43784.1 - 0.0065 16.3 0.0 1.5 8.6 0.0 2.3 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 KXL43784.1 - 0.14 11.9 0.1 0.82 9.5 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain FeoB_N PF02421.18 KXL43784.1 - 0.23 11.0 0.4 62 3.1 0.1 3.1 3 0 0 3 3 3 0 Ferrous iron transport protein B ANAPC1 PF12859.7 KXL43785.1 - 1.2e-27 97.0 1.0 1.2e-27 97.0 1.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 KXL43785.1 - 0.26 11.8 6.8 25 5.5 0.8 4.6 4 0 0 4 4 4 0 Proteasome/cyclosome repeat Ribosomal_L31 PF01197.18 KXL43787.1 - 0.0009 19.4 0.0 0.0015 18.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L31 DUF2385 PF09539.10 KXL43787.1 - 0.16 12.5 0.0 0.24 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2385) DUF2439 PF10382.9 KXL43788.1 - 1.4e-27 95.8 0.0 2e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) zf-C3HC4_3 PF13920.6 KXL43789.1 - 0.011 15.6 12.0 0.019 14.8 12.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 KXL43789.1 - 0.1 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 U-box domain zf-RING_6 PF14835.6 KXL43789.1 - 0.29 11.0 5.4 0.52 10.2 5.4 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Abhydrolase_3 PF07859.13 KXL43790.1 - 4.2e-21 75.8 0.0 6.4e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXL43790.1 - 8.7e-20 70.9 0.0 1.4e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase UCH PF00443.29 KXL43792.1 - 4.5e-67 226.2 0.0 7.1e-67 225.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KXL43792.1 - 7.9e-11 42.4 0.0 8.1e-10 39.2 0.0 2.5 2 0 0 2 2 2 1 DUSP domain UCH_1 PF13423.6 KXL43792.1 - 2.3e-10 40.6 0.0 0.00055 19.6 0.0 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 KXL43792.1 - 0.029 14.1 0.0 0.077 12.7 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin-specific protease C-terminal ubiquitin PF00240.23 KXL43792.1 - 0.12 12.1 0.0 0.52 10.1 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin family Abhydrolase_1 PF00561.20 KXL43793.1 - 1.8e-44 152.3 0.0 1.2e-43 149.6 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KXL43793.1 - 0.00043 20.0 0.1 0.00071 19.3 0.1 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 KXL43793.1 - 0.026 14.3 0.1 0.097 12.5 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KXL43793.1 - 0.032 13.5 0.2 0.062 12.6 0.2 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MRP-L46 PF11788.8 KXL43796.1 - 6.7e-35 120.4 1.0 3.8e-34 118.0 1.0 2.0 1 1 0 1 1 1 1 39S mitochondrial ribosomal protein L46 zf-C3HC4_3 PF13920.6 KXL43797.1 - 6.9e-10 38.6 10.0 6.9e-10 38.6 10.0 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXL43797.1 - 5.8e-05 22.9 9.0 0.00017 21.4 9.0 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Med9 PF07544.13 KXL43797.1 - 0.68 10.1 6.4 0.87 9.7 3.5 2.7 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF1230 PF06799.11 KXL43798.1 - 0.052 13.7 1.8 0.12 12.5 1.8 1.6 1 0 0 1 1 1 0 Conserved in the green lineage and diatoms 27 DUF3398 PF11878.8 KXL43799.1 - 0.033 14.6 0.1 0.05 14.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3398) APO_RNA-bind PF05634.11 KXL43799.1 - 0.081 12.3 0.1 0.1 12.0 0.1 1.1 1 0 0 1 1 1 0 APO RNA-binding Rab5ip PF07019.12 KXL43800.1 - 5.6e-28 97.4 7.4 6.1e-28 97.2 7.4 1.0 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) PCNA_N PF00705.18 KXL43801.1 - 5.4e-56 187.7 2.6 2.2e-55 185.8 2.7 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KXL43801.1 - 2.5e-51 173.2 0.0 1.7e-50 170.5 0.0 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 KXL43801.1 - 2.7e-07 30.3 0.0 3.4e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.12 KXL43801.1 - 0.00033 19.9 0.3 0.0028 16.8 0.1 2.2 2 1 0 2 2 2 1 Hus1-like protein DUF2576 PF10845.8 KXL43801.1 - 0.038 13.6 2.8 0.041 13.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2576) 3-HAO PF06052.12 KXL43803.1 - 1.2e-57 193.8 0.0 1.5e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 KXL43803.1 - 0.00015 21.4 0.0 0.00024 20.8 0.0 1.3 1 0 0 1 1 1 1 Cupin domain DZR PF12773.7 KXL43803.1 - 0.0081 16.2 5.7 0.014 15.4 5.7 1.4 1 0 0 1 1 1 1 Double zinc ribbon Cupin_1 PF00190.22 KXL43803.1 - 0.021 14.4 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Cupin zf-ribbon_3 PF13248.6 KXL43803.1 - 0.029 13.8 3.8 0.22 11.0 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain ARD PF03079.14 KXL43803.1 - 0.031 14.5 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 ARD/ARD' family AraC_binding PF02311.19 KXL43803.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain HalOD2 PF18547.1 KXL43803.1 - 0.11 12.4 1.0 10 6.1 0.1 2.3 2 0 0 2 2 2 0 Halobacterial output domain 2 zinc_ribbon_10 PF10058.9 KXL43803.1 - 0.12 12.1 2.1 1.9 8.3 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein TF_Zn_Ribbon PF08271.12 KXL43803.1 - 0.23 11.0 2.3 7.3 6.2 0.9 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding NinF PF05810.12 KXL43803.1 - 0.38 10.6 2.5 0.43 10.5 0.1 2.2 2 0 0 2 2 2 0 NinF protein Zn-ribbon_8 PF09723.10 KXL43803.1 - 0.59 10.3 6.6 34 4.6 6.6 2.4 1 1 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_2 PF13240.6 KXL43803.1 - 1.4 8.8 9.7 2.7 7.8 0.7 2.6 3 0 0 3 3 3 0 zinc-ribbon domain C1_1 PF00130.22 KXL43803.1 - 1.5 8.7 8.1 4 7.4 1.8 2.2 1 1 2 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ADK_lid PF05191.14 KXL43803.1 - 3 7.9 5.9 20 5.2 5.7 2.3 1 1 1 2 2 2 0 Adenylate kinase, active site lid Nop14 PF04147.12 KXL43805.1 - 3e-229 763.6 32.8 4.1e-178 594.4 15.6 2.1 1 1 1 2 2 2 2 Nop14-like family DUF1788 PF08747.11 KXL43805.1 - 0.0013 18.8 0.3 1.1 9.3 0.0 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF1788) PBC PF03792.13 KXL43805.1 - 0.0014 18.4 2.2 0.0015 18.4 0.1 2.1 2 0 0 2 2 2 1 PBC domain VIT PF08487.10 KXL43805.1 - 0.8 9.9 4.2 2.4 8.4 0.0 3.2 2 1 0 3 3 3 0 Vault protein inter-alpha-trypsin domain ADH_N PF08240.12 KXL43806.1 - 2.4e-26 91.8 4.0 5.7e-26 90.5 4.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXL43806.1 - 4.7e-18 65.4 0.1 9e-18 64.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXL43806.1 - 8.2e-07 28.7 0.1 1.3e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KXL43806.1 - 1.7e-06 27.5 0.3 2.9e-06 26.7 0.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_N_assoc PF13823.6 KXL43806.1 - 0.00082 19.3 0.3 0.0017 18.2 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.6 KXL43806.1 - 0.0037 18.3 0.0 0.0067 17.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_8 PF13450.6 KXL43806.1 - 0.013 15.8 0.2 0.071 13.4 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXL43806.1 - 0.016 14.5 0.1 0.023 13.9 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXL43806.1 - 0.04 13.0 0.1 0.059 12.5 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 KXL43806.1 - 0.086 13.1 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.14 KXL43806.1 - 0.15 10.7 0.2 0.21 10.3 0.2 1.1 1 0 0 1 1 1 0 HI0933-like protein Vezatin PF12632.7 KXL43807.1 - 3.9e-18 65.8 0.0 2.9e-17 63.0 0.0 2.2 2 1 1 3 3 3 1 Mysoin-binding motif of peroxisomes Cluap1 PF10234.9 KXL43807.1 - 0.0015 18.0 7.1 0.0052 16.2 0.1 2.2 1 1 1 2 2 2 1 Clusterin-associated protein-1 Syntaxin PF00804.25 KXL43807.1 - 0.0088 15.7 0.3 0.0088 15.7 0.3 2.2 2 0 0 2 2 2 1 Syntaxin DASH_Hsk3 PF08227.11 KXL43807.1 - 0.044 14.1 0.8 1.3 9.5 0.0 2.4 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like TPR_MLP1_2 PF07926.12 KXL43807.1 - 0.57 10.3 9.7 0.095 12.8 2.0 2.7 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KXL43807.1 - 4.9 6.0 10.0 0.25 10.2 0.6 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein FAD_binding_2 PF00890.24 KXL43808.1 - 2.9e-81 273.7 0.2 3.6e-81 273.4 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 KXL43808.1 - 3.3e-21 75.2 0.6 6.6e-19 67.8 0.0 3.6 5 0 0 5 5 4 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 KXL43808.1 - 5.6e-13 49.2 0.0 1.1e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KXL43808.1 - 7.5e-10 38.7 0.2 2.5e-09 37.0 0.2 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXL43808.1 - 2.8e-09 36.6 0.1 1.1e-08 34.7 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXL43808.1 - 3.6e-08 33.5 0.2 2.3e-07 30.9 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXL43808.1 - 3.4e-06 26.5 0.0 0.028 13.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXL43808.1 - 8.6e-06 24.7 5.3 2.3e-05 23.3 0.7 2.8 2 1 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KXL43808.1 - 4.6e-05 22.7 0.4 0.012 14.8 0.1 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 KXL43808.1 - 0.00048 19.4 0.1 0.058 12.6 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 KXL43808.1 - 0.0013 18.1 0.3 4.7 6.4 0.1 3.3 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KXL43808.1 - 0.0051 17.3 1.3 4.1 8.0 0.1 3.0 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXL43808.1 - 0.0067 15.7 0.3 0.021 14.1 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 KXL43808.1 - 0.0083 16.1 0.4 0.13 12.3 0.4 2.5 1 1 0 1 1 1 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KXL43808.1 - 0.03 13.6 0.0 0.057 12.7 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PALP PF00291.25 KXL43809.1 - 5.6e-64 216.4 0.3 7.6e-64 215.9 0.3 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KXL43809.1 - 0.06 12.7 0.1 0.099 11.9 0.1 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Trehalase PF01204.18 KXL43810.1 - 2e-190 634.0 0.6 2.4e-190 633.7 0.6 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 KXL43810.1 - 3.9e-15 55.3 1.8 6.7e-15 54.5 1.8 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain NRDE-2 PF08424.10 KXL43811.1 - 9.1e-85 284.6 5.5 2e-84 283.5 0.3 2.9 3 0 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_16 PF13432.6 KXL43811.1 - 0.0011 19.6 1.2 0.009 16.6 0.5 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXL43811.1 - 0.0052 17.1 1.3 0.059 13.7 0.5 2.8 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXL43811.1 - 0.0072 16.6 0.6 0.045 14.1 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat T3SS_needle_reg PF09025.10 KXL43811.1 - 0.066 13.2 0.3 0.43 10.6 0.1 2.4 2 0 0 2 2 2 0 YopR, type III needle-polymerisation regulator TPR_9 PF13371.6 KXL43811.1 - 0.067 13.3 0.5 0.25 11.5 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXL43811.1 - 0.11 12.6 2.7 0.18 12.0 0.6 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXL43811.1 - 1.5 9.9 14.0 11 7.2 0.6 6.5 6 1 1 7 7 7 0 Tetratricopeptide repeat BP28CT PF08146.12 KXL43812.1 - 1.2e-36 125.9 2.7 6.7e-36 123.5 1.5 2.8 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 KXL43812.1 - 1.2e-19 70.7 2.4 4.8e-19 68.8 0.5 3.2 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.22 KXL43812.1 - 5.6e-08 32.4 13.4 0.23 11.8 0.1 6.3 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 KXL43812.1 - 4e-05 23.9 7.4 0.017 15.5 0.9 5.3 4 0 0 4 4 4 2 HEAT repeats EBP PF05241.12 KXL43813.1 - 2.1e-52 177.2 11.3 2.5e-52 176.9 11.3 1.0 1 0 0 1 1 1 1 Emopamil binding protein Voltage_CLC PF00654.20 KXL43813.1 - 0.00039 19.8 3.9 0.00054 19.3 3.9 1.4 1 1 0 1 1 1 1 Voltage gated chloride channel ATG27 PF09451.10 KXL43814.1 - 2.4e-96 322.6 0.0 3e-96 322.3 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 KXL43814.1 - 0.019 15.0 0.1 0.48 10.5 0.0 2.3 2 0 0 2 2 2 0 Cation-independent mannose-6-phosphate receptor repeat TruD PF01142.18 KXL43815.1 - 2.9e-60 204.2 0.2 2.2e-58 198.0 0.1 2.6 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Peptidase_S10 PF00450.22 KXL43816.1 - 2.2e-127 426.0 0.1 2.6e-127 425.7 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 KXL43816.1 - 9.8e-16 58.4 1.7 2.4e-15 57.2 1.7 1.7 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide NmrA PF05368.13 KXL43818.1 - 1.3e-08 34.7 0.0 7.5e-06 25.7 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family PEX11 PF05648.14 KXL43819.1 - 3.5e-11 43.0 0.8 3.1e-10 39.9 0.8 2.4 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Mg_trans_NIPA PF05653.14 KXL43821.1 - 3.2e-100 335.1 12.8 4.6e-100 334.5 12.8 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KXL43821.1 - 9.7e-07 29.0 6.1 9.7e-07 29.0 6.1 3.2 3 0 0 3 3 3 1 EamA-like transporter family DUF4131 PF13567.6 KXL43821.1 - 0.11 12.2 2.1 26 4.4 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) PIRT PF15099.6 KXL43821.1 - 2.3 7.8 4.1 2.7 7.6 0.5 2.3 1 1 1 2 2 2 0 Phosphoinositide-interacting protein family CDP-OH_P_transf PF01066.21 KXL43822.1 - 1e-12 48.6 0.6 1e-12 48.6 0.6 2.3 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Cellulase PF00150.18 KXL43823.1 - 1.1e-48 166.1 0.0 1.5e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KXL43823.1 - 1.4e-11 44.1 16.4 1.4e-11 44.1 16.4 2.9 3 0 0 3 3 3 1 Fungal cellulose binding domain Fungal_trans PF04082.18 KXL43824.1 - 2e-10 40.2 0.0 8.1e-10 38.2 0.0 2.0 1 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL43824.1 - 2e-09 37.4 8.6 4.3e-09 36.3 8.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Arrestin_N PF00339.29 KXL43825.1 - 0.0014 18.7 0.1 0.0041 17.2 0.1 1.8 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KXL43825.1 - 0.018 15.5 0.0 2.1 8.8 0.0 2.5 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Bul1_C PF04426.12 KXL43825.1 - 0.037 13.4 0.0 0.066 12.6 0.0 1.4 1 0 0 1 1 1 0 Bul1 C terminus Oxidored_molyb PF00174.19 KXL43827.1 - 1.3e-53 181.1 0.0 2.1e-53 180.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KXL43827.1 - 3.3e-37 127.6 0.6 7e-37 126.5 0.6 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.24 KXL43827.1 - 1.1e-21 77.0 0.0 1.4e-09 38.2 0.0 2.5 1 1 1 2 2 2 2 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KXL43827.1 - 2.9e-21 76.2 0.0 6.8e-20 71.7 0.0 3.2 4 1 1 5 5 5 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 KXL43827.1 - 1.7e-14 53.7 0.2 6.6e-14 51.8 0.1 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KXL43827.1 - 0.0052 16.9 0.0 0.46 10.6 0.0 2.6 1 1 1 2 2 2 1 Ferric reductase NAD binding domain IFRD PF05004.13 KXL43828.1 - 4.8e-85 285.4 5.2 4.8e-85 285.4 5.2 1.4 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) HHH_9 PF17674.1 KXL43828.1 - 0.01 16.8 0.1 0.031 15.2 0.1 1.9 1 0 0 1 1 1 1 HHH domain FAA_hydro_N_2 PF18288.1 KXL43828.1 - 0.027 14.9 0.1 0.077 13.4 0.1 1.7 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 Caps_synth_GfcC PF06251.11 KXL43828.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Capsule biosynthesis GfcC Chitin_synth_1 PF01644.17 KXL43829.1 - 1.2e-68 230.3 0.0 1.7e-68 229.7 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KXL43829.1 - 5.6e-28 96.7 0.0 1.1e-27 95.8 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KXL43829.1 - 3.7e-24 85.3 4.2 5.5e-21 74.8 0.0 2.4 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KXL43829.1 - 0.0029 17.5 20.8 0.0033 17.4 15.5 3.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 DUF218 PF02698.17 KXL43830.1 - 8.3e-07 29.1 0.0 1.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain Ten1 PF12658.7 KXL43831.1 - 2.5e-29 101.7 0.0 3e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.6 KXL43831.1 - 0.00023 20.9 0.0 0.00027 20.7 0.0 1.3 1 1 0 1 1 1 1 Telomere-capping, CST complex subunit Snf7 PF03357.21 KXL43832.1 - 1.5e-34 119.1 23.9 1.5e-34 119.1 23.9 2.0 1 1 1 2 2 2 1 Snf7 BAF1_ABF1 PF04684.13 KXL43832.1 - 2.1 7.3 15.8 2.3 7.2 15.8 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PIN_8 PF18476.1 KXL43832.1 - 2.1 8.1 11.6 5.2 6.8 11.6 1.7 1 1 0 1 1 1 0 PIN like domain SpoIISA_toxin PF14171.6 KXL43832.1 - 8.7 6.0 7.1 13 5.4 7.1 1.2 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system CH PF00307.31 KXL43833.1 - 5e-13 49.2 0.0 1e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain ARGLU PF15346.6 KXL43833.1 - 0.0036 17.2 40.4 0.0036 17.2 40.4 2.1 2 0 0 2 2 2 1 Arginine and glutamate-rich 1 DUF4677 PF15726.5 KXL43833.1 - 0.16 12.1 0.4 0.43 10.7 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4677) CDC24 PF06395.11 KXL43833.1 - 0.26 11.6 0.0 0.46 10.8 0.0 1.3 1 0 0 1 1 1 0 CDC24 Calponin DUF4588 PF15251.6 KXL43834.1 - 4.2e-07 30.0 0.1 6.6e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4588) Glyco_tranf_2_2 PF10111.9 KXL43834.1 - 0.081 12.4 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase like family 2 ECR1_N PF14382.6 KXL43835.1 - 2.5e-10 40.0 0.4 7.3e-10 38.5 0.2 2.0 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 KXL43835.1 - 0.00035 20.9 0.5 0.0012 19.1 0.7 1.9 2 0 0 2 2 2 1 KH domain ECH_1 PF00378.20 KXL43837.1 - 1.2e-44 152.5 0.0 6.5e-44 150.1 0.0 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXL43837.1 - 2e-33 116.3 0.0 1.3e-32 113.7 0.0 1.9 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase PPR_2 PF13041.6 KXL43839.1 - 0.0099 16.1 0.0 0.17 12.1 0.0 2.5 2 0 0 2 2 2 1 PPR repeat family PPR_long PF17177.4 KXL43839.1 - 0.12 11.7 0.1 0.41 10.0 0.0 1.9 2 0 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP MRC1 PF09444.10 KXL43840.1 - 2.8e-19 70.1 14.1 2.8e-19 70.1 14.1 6.6 6 3 1 7 7 7 1 MRC1-like domain NDUFA12 PF05071.16 KXL43841.1 - 1e-10 42.3 1.6 1.1e-10 42.2 0.2 1.9 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 ArsA_ATPase PF02374.15 KXL43842.1 - 1.7e-105 352.6 0.0 1.9e-105 352.4 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 KXL43842.1 - 1.6e-13 51.0 0.0 1.6e-12 47.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 KXL43842.1 - 6.4e-12 45.6 0.0 1e-11 45.0 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 KXL43842.1 - 2.6e-05 23.8 1.1 0.0002 20.9 0.2 2.5 3 0 0 3 3 3 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 KXL43842.1 - 4.1e-05 23.3 0.1 0.0024 17.6 0.2 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_NifH PF00142.18 KXL43842.1 - 4.8e-05 22.9 0.1 0.0001 21.9 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 KXL43842.1 - 0.00063 19.4 0.5 0.0051 16.4 0.5 2.1 1 1 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 KXL43842.1 - 0.00072 19.1 0.0 0.0048 16.4 0.0 2.1 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ Zeta_toxin PF06414.12 KXL43842.1 - 0.0031 16.8 0.0 0.0057 16.0 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin PhoH PF02562.16 KXL43842.1 - 0.047 13.1 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.22 KXL43842.1 - 0.073 12.2 0.1 0.29 10.3 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain Med8 PF10232.9 KXL43842.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 His_Phos_1 PF00300.22 KXL43845.1 - 0.0039 16.9 0.2 0.0068 16.1 0.2 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Tyr_Deacylase PF02580.16 KXL43846.1 - 2.1e-51 174.2 0.3 3e-51 173.7 0.3 1.2 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Not3 PF04065.15 KXL43847.1 - 1.1e-86 290.1 18.8 1.5e-86 289.6 18.8 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component Cep57_MT_bd PF06657.13 KXL43847.1 - 0.013 15.9 5.2 0.25 11.8 1.1 2.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF1192 PF06698.11 KXL43847.1 - 0.078 13.0 0.9 0.27 11.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Cluap1 PF10234.9 KXL43847.1 - 0.091 12.2 7.9 0.17 11.3 7.9 1.4 1 0 0 1 1 1 0 Clusterin-associated protein-1 CorA PF01544.18 KXL43847.1 - 1.3 8.2 3.7 0.52 9.6 0.9 1.6 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF4407 PF14362.6 KXL43847.1 - 2.8 7.2 5.4 5.5 6.3 5.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Glyco_hydro_7 PF00840.20 KXL43848.1 - 2.5e-24 85.8 0.6 2.6e-24 85.7 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 RhoGAP PF00620.27 KXL43851.1 - 1.3e-44 151.7 0.0 2.4e-44 150.9 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 KXL43851.1 - 3.9e-10 39.9 0.2 1.2e-09 38.3 0.2 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Filament PF00038.21 KXL43851.1 - 0.46 10.0 7.1 0.11 12.0 1.9 2.0 2 0 0 2 2 2 0 Intermediate filament protein DeoC PF01791.9 KXL43852.1 - 3.1e-17 63.0 0.7 4.1e-17 62.6 0.7 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase DHO_dh PF01180.21 KXL43852.1 - 0.0058 15.9 0.2 0.014 14.6 0.1 1.5 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.21 KXL43852.1 - 0.017 14.6 0.1 0.04 13.4 0.0 1.6 2 0 0 2 2 2 0 Histidine biosynthesis protein adh_short_C2 PF13561.6 KXL43853.1 - 8.4e-60 202.2 0.1 9.6e-60 202.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL43853.1 - 6.3e-47 159.6 0.0 8e-47 159.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL43853.1 - 1.9e-06 27.9 0.0 2.8e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KXL43853.1 - 0.065 13.1 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KXL43853.1 - 0.18 10.8 0.0 0.42 9.6 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DLH PF01738.18 KXL43854.1 - 1.7e-25 89.9 0.0 2.1e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 KXL43854.1 - 0.011 15.6 0.0 0.34 10.8 0.0 2.1 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 KXL43854.1 - 0.027 14.0 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) LIDHydrolase PF10230.9 KXL43854.1 - 0.046 13.3 0.0 0.062 12.8 0.0 1.1 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase p450 PF00067.22 KXL43858.1 - 1.3e-07 30.8 0.0 3.5e-05 22.8 0.0 2.2 2 1 0 2 2 2 2 Cytochrome P450 zf-RING_UBOX PF13445.6 KXL43859.1 - 5.6e-09 35.9 1.9 5.6e-09 35.9 1.9 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXL43859.1 - 4e-08 33.0 5.2 1.6e-07 31.0 2.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXL43859.1 - 2.6e-07 30.4 5.8 4.2e-07 29.7 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXL43859.1 - 5.7e-07 29.6 3.8 3.4e-06 27.1 4.3 1.9 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KXL43859.1 - 6.5e-06 26.4 7.4 7.1e-05 23.1 8.1 2.1 1 1 1 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KXL43859.1 - 2.2e-05 24.3 4.7 3.9e-05 23.5 4.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXL43859.1 - 0.00026 20.8 6.2 0.00062 19.6 6.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TerY_C PF15616.6 KXL43859.1 - 0.024 14.7 0.1 0.047 13.8 0.1 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain Prok-RING_4 PF14447.6 KXL43859.1 - 0.038 13.9 8.0 0.66 9.9 8.2 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KXL43859.1 - 0.19 11.5 5.9 0.24 11.2 3.4 2.3 2 0 0 2 2 2 0 RING-like zinc finger zf-MIZ PF02891.20 KXL43859.1 - 1.7 8.5 8.4 4.7 7.0 8.5 1.8 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger Gag_spuma PF03276.14 KXL43859.1 - 6.7 5.0 12.1 0.081 11.4 1.1 2.2 2 0 0 2 2 2 0 Spumavirus gag protein zf-rbx1 PF12678.7 KXL43859.1 - 9.4 6.6 7.4 29 5.0 7.4 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain Ribosomal_S27e PF01667.17 KXL43860.1 - 7.4e-29 99.2 6.8 9e-29 99.0 6.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-C2HC5 PF06221.13 KXL43860.1 - 0.32 11.0 5.7 0.98 9.5 2.8 2.3 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-CSL PF05207.13 KXL43860.1 - 0.45 10.3 3.3 1.3 8.8 3.3 1.7 1 1 0 1 1 1 0 CSL zinc finger Peptidase_C65 PF10275.9 KXL43861.1 - 4.9e-67 226.0 0.0 6.4e-67 225.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain Pentapeptide_3 PF13576.6 KXL43861.1 - 0.39 10.9 2.2 2.5 8.3 0.8 2.3 1 1 0 2 2 2 0 Pentapeptide repeats (9 copies) PCI PF01399.27 KXL43862.1 - 2.5e-19 69.7 0.6 5.2e-19 68.7 0.1 1.8 2 0 0 2 2 2 1 PCI domain TPR_7 PF13176.6 KXL43862.1 - 0.0074 16.2 1.2 7.1 6.9 0.0 4.3 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXL43862.1 - 0.033 14.3 3.1 1.3 9.3 0.1 4.4 5 1 0 5 5 5 0 Tetratricopeptide repeat Sulfotransfer_1 PF00685.27 KXL43862.1 - 0.078 12.4 0.4 0.23 10.9 0.2 1.8 2 0 0 2 2 2 0 Sulfotransferase domain TPR_1 PF00515.28 KXL43862.1 - 0.42 10.5 5.0 1.7 8.6 0.1 4.3 5 1 0 5 5 5 0 Tetratricopeptide repeat CWC25 PF12542.8 KXL43863.1 - 5e-24 85.1 0.0 5e-24 85.1 0.0 3.7 3 2 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 KXL43863.1 - 2e-13 50.3 11.9 2e-13 50.3 11.9 4.1 4 1 1 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR Ras PF00071.22 KXL43864.1 - 7.5e-52 175.2 0.0 8.7e-52 175.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXL43864.1 - 7e-21 74.7 0.0 1.2e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXL43864.1 - 6.7e-09 35.4 0.0 1.1e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KXL43864.1 - 0.0024 17.3 0.0 0.0033 16.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KXL43864.1 - 0.0043 16.4 0.0 0.0059 16.0 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KXL43864.1 - 0.0085 15.3 0.0 0.015 14.5 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit MMR_HSR1 PF01926.23 KXL43864.1 - 0.036 14.1 0.0 0.065 13.3 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 KXL43864.1 - 0.12 12.9 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 KXL43864.1 - 0.14 12.0 0.0 13 5.7 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Annexin PF00191.20 KXL43865.1 - 1e-23 83.2 10.5 1.9e-07 31.1 0.9 4.7 4 1 0 4 4 4 4 Annexin CorA PF01544.18 KXL43866.1 - 2.5e-12 46.7 0.1 4.3e-12 46.0 0.1 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein HTH_38 PF13936.6 KXL43869.1 - 1e-10 41.2 0.0 1.3e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.22 KXL43869.1 - 8.8e-06 25.6 0.0 1.1e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 MarR family HTH_23 PF13384.6 KXL43869.1 - 1.5e-05 24.6 0.1 2e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_24 PF13412.6 KXL43869.1 - 2.2e-05 23.9 0.1 2.9e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 KXL43869.1 - 5e-05 23.3 0.5 7.5e-05 22.8 0.5 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 KXL43869.1 - 6.6e-05 22.7 0.0 9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_Tnp_Tc3_1 PF11427.8 KXL43869.1 - 0.00011 21.9 0.0 0.00013 21.7 0.0 1.1 1 0 0 1 1 1 1 Tc3 transposase HTH_29 PF13551.6 KXL43869.1 - 0.00026 20.9 0.3 0.0004 20.4 0.3 1.3 1 1 0 1 1 1 1 Winged helix-turn helix Trp_repressor PF01371.19 KXL43869.1 - 0.00042 20.4 0.0 0.00049 20.2 0.0 1.1 1 0 0 1 1 1 1 Trp repressor protein HTH_3 PF01381.22 KXL43869.1 - 0.00051 20.0 0.0 0.00081 19.4 0.0 1.3 1 1 0 1 1 1 1 Helix-turn-helix HTH_Crp_2 PF13545.6 KXL43869.1 - 0.00059 19.8 0.0 0.00069 19.5 0.0 1.1 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_7 PF02796.15 KXL43869.1 - 0.0011 19.0 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_36 PF13730.6 KXL43869.1 - 0.0012 18.7 0.0 0.0016 18.3 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 KXL43869.1 - 0.0033 17.1 0.0 0.0039 16.8 0.0 1.2 1 0 0 1 1 1 1 Sigma-70, region 4 Fe_dep_repress PF01325.19 KXL43869.1 - 0.0035 17.5 0.0 0.0049 17.0 0.0 1.2 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain TrmB PF01978.19 KXL43869.1 - 0.0039 17.1 0.0 0.0046 16.8 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_31 PF13560.6 KXL43869.1 - 0.0053 17.1 0.5 0.0089 16.3 0.5 1.4 1 1 0 1 1 1 1 Helix-turn-helix domain GntR PF00392.21 KXL43869.1 - 0.012 15.3 0.0 0.015 15.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_27 PF13463.6 KXL43869.1 - 0.021 15.3 0.0 0.031 14.8 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_AsnC-type PF13404.6 KXL43869.1 - 0.023 14.5 0.3 0.12 12.2 0.1 1.9 1 1 1 2 2 2 0 AsnC-type helix-turn-helix domain HTH_11 PF08279.12 KXL43869.1 - 0.024 14.6 0.1 0.032 14.2 0.1 1.2 1 0 0 1 1 1 0 HTH domain HTH_19 PF12844.7 KXL43869.1 - 0.057 13.5 0.0 0.065 13.3 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KXL43869.1 - 0.057 12.8 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Terminase_5 PF06056.12 KXL43869.1 - 0.062 13.2 0.0 0.073 13.0 0.0 1.1 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Rrf2 PF02082.20 KXL43869.1 - 0.079 13.3 0.0 0.088 13.2 0.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator TnsD PF15978.5 KXL43869.1 - 0.086 11.8 0.0 0.086 11.8 0.0 1.0 1 0 0 1 1 1 0 Tn7-like transposition protein D HTH_IclR PF09339.10 KXL43869.1 - 0.1 12.4 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 IclR helix-turn-helix domain CENP-B_N PF04218.13 KXL43869.1 - 0.1 12.2 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_37 PF13744.6 KXL43869.1 - 0.13 12.3 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain Crp PF00325.20 KXL43869.1 - 0.15 11.8 0.3 0.25 11.0 0.3 1.4 1 1 0 1 1 1 0 Bacterial regulatory proteins, crp family Myb_DNA-binding PF00249.31 KXL43872.1 - 2.1e-24 85.4 0.5 3.2e-14 52.8 0.1 2.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXL43872.1 - 2.2e-17 63.1 0.5 3.3e-13 49.7 0.0 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 KXL43872.1 - 0.0002 21.3 0.0 0.0015 18.6 0.0 1.9 1 1 1 2 2 2 1 SLIDE HTH_23 PF13384.6 KXL43872.1 - 0.02 14.7 0.1 0.038 13.8 0.1 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Myb_DNA-bind_4 PF13837.6 KXL43872.1 - 0.042 14.2 2.6 0.14 12.6 0.3 2.5 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Sigma70_r4_2 PF08281.12 KXL43872.1 - 0.058 13.1 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 DUF2774 PF11242.8 KXL43872.1 - 0.067 13.4 0.0 0.16 12.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) Rap1_C PF11626.8 KXL43872.1 - 0.075 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain 2-oxoacid_dh PF00198.23 KXL43875.1 - 6.5e-74 248.3 0.3 8e-74 248.0 0.3 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KXL43875.1 - 2.7e-17 62.4 0.4 7.1e-17 61.0 0.4 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KXL43875.1 - 2.9e-15 56.3 0.3 9.2e-15 54.7 0.3 1.9 1 0 0 1 1 1 1 e3 binding domain Sec7 PF01369.20 KXL43876.1 - 4.8e-72 241.5 1.7 7.2e-72 240.9 0.3 2.1 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 KXL43876.1 - 5.5e-38 130.4 0.1 5.5e-38 130.4 0.1 2.6 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KXL43876.1 - 9e-32 108.8 0.1 9e-32 108.8 0.1 5.3 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) DCB PF16213.5 KXL43876.1 - 6e-22 78.2 1.1 6e-22 78.2 1.1 2.8 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 CLASP_N PF12348.8 KXL43877.1 - 6.4e-113 375.9 2.2 5.3e-78 261.7 0.0 3.1 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.22 KXL43877.1 - 6.9e-05 22.8 1.3 1 9.8 0.0 5.5 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 KXL43877.1 - 0.014 15.8 8.3 1.3 9.4 0.1 4.5 3 2 1 4 4 4 0 HEAT repeats DUF3361 PF11841.8 KXL43877.1 - 0.021 14.7 0.0 0.063 13.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) Cohesin_HEAT PF12765.7 KXL43877.1 - 0.41 11.0 1.6 28 5.1 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion KH_1 PF00013.29 KXL43878.1 - 9.1e-34 115.1 5.2 1.8e-07 30.8 0.0 7.3 8 0 0 8 8 8 5 KH domain Pfg27 PF09216.10 KXL43878.1 - 1.1 9.0 4.6 1 9.2 0.1 2.6 3 0 0 3 3 3 0 Pfg27 BSP PF04450.12 KXL43879.1 - 2.3e-67 226.8 0.0 2.7e-67 226.6 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria SprT-like PF10263.9 KXL43879.1 - 0.018 14.9 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 SprT-like family RhoGAP PF00620.27 KXL43880.1 - 1.6e-47 161.1 0.0 5e-47 159.5 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain DUF1708 PF08101.11 KXL43880.1 - 0.0026 17.0 0.3 0.039 13.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1708) PhoU PF01895.19 KXL43880.1 - 0.0055 17.1 1.6 0.019 15.4 1.6 1.9 1 0 0 1 1 1 1 PhoU domain CENP-H PF05837.12 KXL43880.1 - 0.045 14.2 10.5 2.2 8.7 0.0 2.9 2 1 0 2 2 2 0 Centromere protein H (CENP-H) MMR1 PF08505.10 KXL43880.1 - 0.11 12.8 11.3 0.24 11.6 11.3 1.6 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein AAA_23 PF13476.6 KXL43880.1 - 0.22 12.0 6.8 0.52 10.8 6.8 1.6 1 0 0 1 1 1 0 AAA domain Herpes_UL6 PF01763.16 KXL43880.1 - 0.22 10.0 8.2 0.13 10.7 6.3 1.5 1 1 0 1 1 1 0 Herpesvirus UL6 like Fez1 PF06818.15 KXL43880.1 - 0.24 11.8 14.3 0.49 10.8 14.3 1.4 1 0 0 1 1 1 0 Fez1 DUF4407 PF14362.6 KXL43880.1 - 0.35 10.2 8.8 0.63 9.3 8.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 KXL43880.1 - 0.38 9.6 16.3 0.69 8.7 6.5 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF1043 PF06295.12 KXL43880.1 - 1.9 8.5 10.5 0.29 11.1 5.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) TBCA PF02970.16 KXL43880.1 - 5.2 7.5 11.8 2.1 8.7 7.8 2.3 1 1 1 2 2 2 0 Tubulin binding cofactor A LIM PF00412.22 KXL43881.1 - 5.1e-16 58.6 17.2 2.1e-10 40.7 1.7 2.3 2 0 0 2 2 2 2 LIM domain Zn-ribbon_8 PF09723.10 KXL43881.1 - 0.0085 16.2 21.6 0.15 12.2 1.3 4.6 2 1 2 4 4 4 2 Zinc ribbon domain zf-ribbon_3 PF13248.6 KXL43881.1 - 0.03 13.8 21.2 0.13 11.7 0.0 6.0 6 1 0 6 6 6 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 KXL43881.1 - 0.73 9.4 25.2 3.4 7.3 2.6 6.1 5 1 0 5 5 5 0 TFIIB zinc-binding RNHCP PF12647.7 KXL43881.1 - 1.5 8.8 18.6 4.3 7.4 1.2 4.3 2 2 2 4 4 4 0 RNHCP domain Desulfoferrod_N PF06397.12 KXL43881.1 - 4.5 7.0 22.0 3.7 7.2 2.0 4.1 3 1 1 4 4 4 0 Desulfoferrodoxin, N-terminal domain OrfB_Zn_ribbon PF07282.11 KXL43881.1 - 8.3 6.4 19.4 0.52 10.3 0.4 3.9 3 1 1 4 4 4 0 Putative transposase DNA-binding domain TPP_enzyme_N PF02776.18 KXL43882.1 - 5.2e-35 120.6 0.4 8.9e-35 119.8 0.4 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KXL43882.1 - 5.8e-15 55.4 0.1 2.5e-13 50.1 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXL43882.1 - 9.3e-08 31.9 0.0 2.6e-07 30.4 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Tox-MPTase3 PF15639.6 KXL43882.1 - 0.09 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Metallopeptidase toxin 3 MFS_1 PF07690.16 KXL43884.1 - 9.2e-24 84.0 35.4 3.1e-23 82.3 35.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily LapA_dom PF06305.11 KXL43884.1 - 0.12 12.3 1.0 0.84 9.5 0.1 3.0 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Pkinase PF00069.25 KXL43885.1 - 2.2e-57 194.4 0.0 1.7e-51 175.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXL43885.1 - 4.3e-37 127.8 0.1 1.6e-35 122.7 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KXL43885.1 - 2.1e-07 30.6 0.0 6.3e-07 29.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KXL43885.1 - 5.3e-05 22.2 0.5 0.00016 20.6 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KXL43885.1 - 0.0011 18.9 0.1 0.0048 16.8 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Sybindin PF04099.12 KXL43886.1 - 3.3e-25 88.7 0.0 3.9e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family MFS_1 PF07690.16 KXL43887.1 - 4.9e-36 124.4 33.7 6.6e-36 124.0 33.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXL43887.1 - 4.7e-14 51.7 7.1 1.1e-10 40.6 4.6 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXL43887.1 - 5e-10 38.8 31.9 6.5e-10 38.5 10.4 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter DDE_3 PF13358.6 KXL43888.1 - 6.2e-10 39.0 0.0 6.2e-10 39.0 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease MMR_HSR1_Xtn PF16897.5 KXL43889.1 - 2.2e-35 120.9 1.0 7.8e-35 119.1 0.5 2.0 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KXL43889.1 - 1.1e-23 83.0 0.1 1.9e-23 82.3 0.1 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KXL43889.1 - 3.7e-20 72.1 0.0 7.7e-20 71.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXL43889.1 - 9.1e-13 48.0 0.0 1.5e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KXL43889.1 - 0.00025 21.2 0.3 0.2 11.7 0.0 2.4 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 KXL43889.1 - 0.021 14.2 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 AIG1 family MeaB PF03308.16 KXL43889.1 - 0.085 11.8 0.1 0.16 10.9 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MCM PF00493.23 KXL43889.1 - 0.093 11.8 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain MBOAT PF03062.19 KXL43890.1 - 5.5e-54 183.8 11.9 9.3e-54 183.1 11.9 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Histone PF00125.24 KXL43891.1 - 3.3e-39 134.2 0.1 4e-39 134.0 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KXL43891.1 - 9.6e-05 22.5 0.0 0.00014 22.0 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXL43891.1 - 0.00035 20.9 0.1 0.0005 20.4 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KXL43891.1 - 0.0031 17.6 0.0 0.0043 17.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 KXL43891.1 - 0.0073 16.6 0.2 0.011 15.9 0.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DER1 PF04511.15 KXL43892.1 - 2e-49 168.2 7.1 2.3e-49 168.0 7.1 1.0 1 0 0 1 1 1 1 Der1-like family WD40_4 PF16300.5 KXL43892.1 - 0.1 12.5 0.4 0.2 11.6 0.4 1.4 1 0 0 1 1 1 0 Type of WD40 repeat Blt1 PF12754.7 KXL43893.1 - 3.9e-29 101.9 0.3 2.7e-28 99.2 0.2 2.0 2 0 0 2 2 2 1 Blt1 N-terminal domain Blt1_C PF17183.4 KXL43893.1 - 9.9e-14 50.7 0.0 1.7e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Get5 carboxyl domain ubiquitin PF00240.23 KXL43893.1 - 5e-05 23.0 0.1 8.9e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KXL43893.1 - 0.0041 16.9 0.1 0.0073 16.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KXL43893.1 - 0.023 15.0 0.0 0.051 13.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain Pro_isomerase PF00160.21 KXL43894.1 - 1.3e-35 123.0 0.0 2.6e-35 122.0 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pinin_SDK_N PF04697.13 KXL43894.1 - 0.66 10.6 7.8 0.26 11.9 0.7 2.9 1 1 2 3 3 3 0 pinin/SDK conserved region Cofilin_ADF PF00241.20 KXL43895.1 - 4e-40 136.4 0.1 4.5e-40 136.2 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Fumerase PF05681.14 KXL43895.1 - 0.068 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) Cation_ATPase_C PF00689.21 KXL43897.1 - 1.6e-47 161.6 8.8 1.6e-47 161.6 8.8 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KXL43897.1 - 2.1e-37 128.4 1.9 2.1e-37 128.4 1.9 3.0 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase PF13246.6 KXL43897.1 - 4.5e-20 71.5 0.0 9.8e-20 70.5 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXL43897.1 - 5.2e-19 69.4 0.0 1.2e-18 68.1 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXL43897.1 - 1.5e-10 40.6 0.2 1e-09 37.9 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXL43897.1 - 0.00024 20.9 0.5 0.00042 20.1 0.5 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase LptF_LptG PF03739.14 KXL43897.1 - 0.0089 14.9 1.6 0.054 12.3 1.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide export system permease LptF/LptG ETRAMP PF09716.10 KXL43897.1 - 0.06 13.4 1.5 15 5.7 0.0 3.6 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Transposase_20 PF02371.16 KXL43897.1 - 0.18 12.2 0.6 4.6 7.6 0.0 2.7 2 0 0 2 2 2 0 Transposase IS116/IS110/IS902 family RskA PF10099.9 KXL43897.1 - 1.5 9.1 4.8 55 4.0 0.0 3.9 3 1 0 3 3 3 0 Anti-sigma-K factor rskA CwfJ_C_2 PF04676.14 KXL43898.1 - 2.8e-23 82.7 0.0 2.8e-23 82.7 0.0 2.3 2 1 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 KXL43898.1 - 5e-23 81.3 0.0 7.4e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 ATP_bind_1 PF03029.17 KXL43899.1 - 3.6e-64 216.8 0.0 2.5e-63 214.1 0.0 1.9 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KXL43899.1 - 0.00094 18.8 0.0 0.24 10.9 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KXL43899.1 - 0.0018 18.2 0.0 0.52 10.2 0.0 3.0 3 0 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 KXL43899.1 - 0.0021 18.3 0.0 0.0052 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain G-alpha PF00503.20 KXL43899.1 - 0.0021 17.3 0.0 0.033 13.4 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA_30 PF13604.6 KXL43899.1 - 0.0024 17.6 0.0 0.0054 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXL43899.1 - 0.0031 17.9 0.0 0.0081 16.6 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 KXL43899.1 - 0.0036 16.3 0.0 0.32 9.9 0.0 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Ras PF00071.22 KXL43899.1 - 0.004 16.8 0.0 0.091 12.4 0.0 2.3 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 KXL43899.1 - 0.0051 16.9 0.0 3 8.0 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase NB-ARC PF00931.22 KXL43899.1 - 0.0056 15.9 0.0 0.0091 15.2 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 KXL43899.1 - 0.0058 16.6 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Roc PF08477.13 KXL43899.1 - 0.0079 16.4 0.0 2.6 8.3 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Thymidylate_kin PF02223.17 KXL43899.1 - 0.011 15.5 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase SRP54 PF00448.22 KXL43899.1 - 0.011 15.3 0.0 0.031 13.9 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 KXL43899.1 - 0.019 15.1 0.6 0.053 13.7 0.0 2.0 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.12 KXL43899.1 - 0.038 13.3 0.0 0.038 13.3 0.0 1.7 2 0 0 2 2 1 0 Zeta toxin FeoB_N PF02421.18 KXL43899.1 - 0.041 13.4 0.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B cobW PF02492.19 KXL43899.1 - 0.055 13.1 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 KXL43899.1 - 0.072 12.5 0.0 1.5 8.2 0.0 2.6 3 0 0 3 3 3 0 ADP-ribosylation factor family Dynamin_N PF00350.23 KXL43899.1 - 0.073 13.1 0.0 0.27 11.3 0.0 2.0 1 1 0 1 1 1 0 Dynamin family KAP_NTPase PF07693.14 KXL43899.1 - 0.15 11.3 0.0 0.17 11.1 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain AAA_24 PF13479.6 KXL43899.1 - 0.16 11.6 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3948 PF13134.6 KXL43899.1 - 5.8 6.7 5.2 5.1 6.9 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3948) HTH_psq PF05225.16 KXL43902.1 - 0.011 15.5 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 helix-turn-helix, Psq domain AA_permease_2 PF13520.6 KXL43903.1 - 7e-58 196.4 53.8 8.7e-58 196.1 53.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXL43903.1 - 2e-28 99.2 46.3 2.7e-28 98.8 46.3 1.0 1 0 0 1 1 1 1 Amino acid permease HET PF06985.11 KXL43904.1 - 2e-21 76.9 0.0 2.3e-21 76.7 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PRP21_like_P PF12230.8 KXL43905.1 - 2.4e-48 164.9 0.1 2.9e-48 164.6 0.1 1.1 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 KXL43905.1 - 5.1e-07 29.6 0.3 8.5e-07 28.9 0.3 1.4 1 0 0 1 1 1 1 Surp module zf_UBZ PF18439.1 KXL43905.1 - 0.0013 18.3 0.1 0.0024 17.4 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger PMT PF02366.18 KXL43906.1 - 1.2e-85 287.0 16.8 2.2e-85 286.2 16.8 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KXL43906.1 - 5.3e-64 215.5 9.2 5.3e-64 215.5 9.2 2.4 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KXL43906.1 - 1.1e-45 155.8 0.0 1.9e-45 155.0 0.0 1.3 1 0 0 1 1 1 1 MIR domain Phage_spike PF18715.1 KXL43906.1 - 0.033 14.3 0.0 0.076 13.1 0.0 1.5 1 0 0 1 1 1 0 Phage spike trimer UCH PF00443.29 KXL43908.1 - 1.2e-45 156.0 0.0 1.8e-45 155.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXL43908.1 - 1.6e-09 37.8 0.0 1.5e-08 34.6 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase baeRF_family7 PF18849.1 KXL43908.1 - 0.15 12.2 0.1 0.29 11.3 0.1 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 7 Romo1 PF10247.9 KXL43909.1 - 3.9e-28 97.6 10.0 5.3e-28 97.2 10.0 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 KXL43909.1 - 0.0064 16.8 1.6 0.008 16.5 1.6 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family CopD PF05425.13 KXL43909.1 - 0.071 13.5 0.1 0.088 13.2 0.1 1.1 1 0 0 1 1 1 0 Copper resistance protein D Gly-zipper_Omp PF13488.6 KXL43909.1 - 0.21 11.6 4.7 0.44 10.6 4.7 1.4 1 0 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.6 KXL43909.1 - 0.25 11.1 5.2 0.44 10.3 5.2 1.4 1 0 0 1 1 1 0 YMGG-like Gly-zipper FHA PF00498.26 KXL43910.1 - 2.3e-17 63.1 0.2 4.2e-17 62.2 0.2 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KXL43910.1 - 0.00031 21.0 0.0 0.00077 19.7 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain sCache_2 PF17200.4 KXL43910.1 - 0.0089 15.9 2.5 0.0089 15.9 2.5 1.8 2 0 0 2 2 2 1 Single Cache domain 2 DUF4037 PF13228.6 KXL43910.1 - 0.3 11.9 0.9 1.7 9.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4037) ERM PF00769.19 KXL43910.1 - 0.67 9.7 25.8 0.02 14.7 18.4 2.0 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF4407 PF14362.6 KXL43910.1 - 1.7 7.9 13.8 3.6 6.9 13.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Jnk-SapK_ap_N PF09744.9 KXL43910.1 - 2.8 8.2 16.8 0.89 9.8 5.1 2.5 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 MscS_porin PF12795.7 KXL43910.1 - 3.4 7.1 22.9 0.16 11.5 5.2 2.9 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain p450 PF00067.22 KXL43911.1 - 0.00021 20.2 3.5 0.00022 20.1 1.6 2.0 2 1 0 2 2 2 1 Cytochrome P450 DUF3780 PF12635.7 KXL43911.1 - 0.022 14.5 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3780) Dioxygenase_N PF04444.14 KXL43912.1 - 2.4e-19 68.9 0.0 3.2e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CDP-OH_P_transf PF01066.21 KXL43913.1 - 2.9e-17 63.2 0.1 2.9e-17 63.2 0.1 3.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase NIPSNAP PF07978.13 KXL43914.1 - 4.4e-42 142.5 0.2 2.7e-30 104.6 0.1 2.5 2 0 0 2 2 2 2 NIPSNAP Kelch_4 PF13418.6 KXL43915.1 - 6.2e-32 109.4 11.2 7.1e-08 32.3 1.4 6.4 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KXL43915.1 - 7.4e-32 109.0 13.7 3.5e-07 30.3 0.6 5.8 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KXL43915.1 - 6.6e-30 102.6 9.0 6.7e-08 32.3 0.4 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KXL43915.1 - 1.4e-28 98.2 8.5 7.7e-10 38.7 1.8 6.4 4 1 2 6 6 6 5 Kelch motif Kelch_1 PF01344.25 KXL43915.1 - 3.1e-27 93.9 2.6 8.7e-09 34.8 1.0 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 KXL43915.1 - 6.5e-20 70.3 5.4 1.5e-05 24.8 1.0 6.3 6 0 0 6 6 6 5 Kelch motif DUF5082 PF16888.5 KXL43915.1 - 0.0086 16.4 1.9 0.0086 16.4 1.9 7.0 4 3 3 7 7 7 3 Domain of unknown function (DUF5082) DUF1664 PF07889.12 KXL43915.1 - 0.65 10.0 58.4 0.027 14.5 4.3 6.8 3 1 3 7 7 7 0 Protein of unknown function (DUF1664) BAAT_C PF08840.11 KXL43915.1 - 3.5 7.5 5.3 2.6 7.9 2.8 2.0 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Strep_SA_rep PF06696.11 KXL43915.1 - 7.4 6.7 11.5 6.8 6.8 0.1 4.5 4 0 0 4 4 4 0 Streptococcal surface antigen repeat GMC_oxred_N PF00732.19 KXL43916.1 - 4.2e-66 223.3 0.0 8e-66 222.4 0.0 1.5 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXL43916.1 - 2.3e-29 102.7 0.0 3.8e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KXL43916.1 - 2.8e-05 23.9 0.0 0.00094 18.8 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXL43916.1 - 3.9e-05 22.9 0.1 6.2e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KXL43916.1 - 0.00012 21.5 0.0 0.022 14.0 0.1 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXL43916.1 - 0.00018 20.7 0.0 0.01 15.0 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KXL43916.1 - 0.00018 21.6 0.0 0.00039 20.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXL43916.1 - 0.00027 20.3 0.0 0.00049 19.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KXL43916.1 - 0.00099 18.4 0.0 0.0043 16.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXL43916.1 - 0.0077 15.0 0.0 0.021 13.5 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 KXL43916.1 - 0.041 13.9 0.0 0.078 13.0 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding RL10P_insert PF17777.1 KXL43916.1 - 0.059 13.4 0.1 0.15 12.1 0.1 1.7 1 0 0 1 1 1 0 Insertion domain in 60S ribosomal protein L10P FAD_binding_3 PF01494.19 KXL43916.1 - 0.062 12.5 0.0 0.09 12.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Methyltransf_23 PF13489.6 KXL43917.1 - 2.6e-23 82.7 0.0 4.6e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL43917.1 - 1.3e-14 54.7 0.0 2.9e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL43917.1 - 5e-14 52.3 0.0 1.8e-13 50.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL43917.1 - 6.6e-11 42.7 0.0 1.6e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL43917.1 - 1.9e-10 41.3 0.0 5.5e-10 39.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXL43917.1 - 0.00012 21.6 0.0 0.00085 18.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KXL43917.1 - 0.00037 20.0 0.0 0.0032 17.0 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.19 KXL43917.1 - 0.00043 20.4 0.0 0.0012 19.0 0.0 1.7 1 0 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.20 KXL43917.1 - 0.0063 15.8 0.0 0.017 14.4 0.0 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KXL43917.1 - 0.012 15.0 0.0 0.057 12.7 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family HetR_C PF18460.1 KXL43917.1 - 0.012 15.5 0.0 0.23 11.4 0.0 2.3 2 0 0 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain PrmA PF06325.13 KXL43917.1 - 0.021 14.2 0.0 0.045 13.1 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 KXL43917.1 - 0.09 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PEMT PF04191.13 KXL43918.1 - 5.7e-56 187.4 16.1 1.6e-35 121.7 1.3 3.0 3 0 0 3 3 3 2 Phospholipid methyltransferase HECW_N PF16562.5 KXL43918.1 - 0.0074 16.1 0.1 0.017 14.9 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 CBP_BcsG PF11658.8 KXL43918.1 - 0.045 12.1 0.0 0.075 11.4 0.0 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG YWFCY PF14293.6 KXL43918.1 - 3.3 8.1 6.7 2.3 8.6 0.2 3.8 4 0 0 4 4 4 0 YWFCY protein MFS_1 PF07690.16 KXL43919.1 - 6e-27 94.5 45.8 1.9e-23 83.0 47.0 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily HD-ZIP_N PF04618.12 KXL43919.1 - 0.098 13.2 0.1 0.27 11.8 0.1 1.7 1 1 0 1 1 1 0 HD-ZIP protein N terminus VIR_N PF15912.5 KXL43922.1 - 3.7e-05 23.5 2.2 5.6e-05 22.9 2.2 1.2 1 0 0 1 1 1 1 Virilizer, N-terminal NOA36 PF06524.12 KXL43922.1 - 0.008 15.5 9.5 0.011 15.1 9.5 1.1 1 0 0 1 1 1 1 NOA36 protein FAM176 PF14851.6 KXL43922.1 - 0.068 12.8 2.1 0.11 12.2 2.1 1.3 1 0 0 1 1 1 0 FAM176 family DUF2722 PF10846.8 KXL43922.1 - 0.082 11.8 0.1 0.098 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CENP-B_dimeris PF09026.10 KXL43922.1 - 0.11 12.9 10.2 0.23 11.9 10.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4336 PF14234.6 KXL43922.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4336) Pox_RNA_Pol_19 PF05320.12 KXL43922.1 - 0.28 11.1 2.7 0.46 10.4 2.7 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF4611 PF15387.6 KXL43922.1 - 0.28 11.4 10.7 0.72 10.1 10.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) SDA1 PF05285.12 KXL43922.1 - 0.34 10.3 6.0 0.47 9.8 6.0 1.1 1 0 0 1 1 1 0 SDA1 Sporozoite_P67 PF05642.11 KXL43922.1 - 0.51 8.3 2.2 0.66 8.0 2.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.12 KXL43922.1 - 0.69 8.1 8.0 1.1 7.4 8.0 1.2 1 0 0 1 1 1 0 Nop14-like family PAC1 PF16094.5 KXL43922.1 - 0.72 9.0 2.1 1.2 8.3 2.1 1.3 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 BUD22 PF09073.10 KXL43922.1 - 0.84 8.9 6.0 1.3 8.3 6.0 1.2 1 0 0 1 1 1 0 BUD22 TRAP_alpha PF03896.16 KXL43922.1 - 1.1 8.4 3.1 1.6 7.9 3.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PPP4R2 PF09184.11 KXL43922.1 - 1.5 8.4 8.2 1.9 8.0 8.2 1.1 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.14 KXL43922.1 - 1.8 6.7 6.9 2.5 6.3 6.9 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 KXL43922.1 - 2.1 6.8 4.4 3.3 6.1 4.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Radial_spoke PF04712.12 KXL43922.1 - 2.2 7.1 8.3 3.2 6.6 8.3 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein GCIP PF13324.6 KXL43922.1 - 2.9 7.4 4.9 4.5 6.8 4.9 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Cwf_Cwc_15 PF04889.12 KXL43922.1 - 3.5 7.3 11.1 5.5 6.6 11.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2457 PF10446.9 KXL43922.1 - 7.2 5.6 16.0 12 4.9 16.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 KXL43922.1 - 9.3 4.2 16.0 14 3.6 16.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi Radical_SAM PF04055.21 KXL43923.1 - 1.5e-08 35.2 0.0 2.6e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KXL43923.1 - 0.00047 20.4 0.1 0.00077 19.7 0.1 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF1054 PF06335.12 KXL43923.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1054) Fer4_14 PF13394.6 KXL43923.1 - 0.092 12.9 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain ParA PF10609.9 KXL43924.1 - 7.6e-95 317.0 0.0 8.8e-95 316.8 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KXL43924.1 - 1.7e-07 31.3 0.0 4.3e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 KXL43924.1 - 2e-05 24.0 0.4 0.00026 20.3 0.3 2.3 1 1 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.6 KXL43924.1 - 0.00029 20.8 0.0 0.00092 19.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KXL43924.1 - 0.019 14.9 0.1 0.039 13.9 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 KXL43924.1 - 0.026 14.1 0.1 0.051 13.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_26 PF13500.6 KXL43924.1 - 0.027 14.3 2.9 1.5 8.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 KXL43924.1 - 0.041 13.9 0.0 0.087 12.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CLP1_P PF16575.5 KXL43924.1 - 0.055 13.3 0.0 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_30 PF13604.6 KXL43924.1 - 0.065 13.0 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain MipZ PF09140.11 KXL43924.1 - 0.09 12.0 0.0 0.17 11.1 0.0 1.5 1 1 0 1 1 1 0 ATPase MipZ RNA_helicase PF00910.22 KXL43924.1 - 0.096 13.1 0.1 0.24 11.8 0.1 1.6 1 1 0 1 1 1 0 RNA helicase Fer4_NifH PF00142.18 KXL43924.1 - 0.11 11.9 0.0 0.84 9.0 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Rad17 PF03215.15 KXL43924.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_16 PF13191.6 KXL43924.1 - 0.15 12.4 0.0 0.27 11.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain p450 PF00067.22 KXL43926.1 - 6.1e-73 246.1 0.0 7.8e-73 245.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 KXL43927.1 - 1.7e-72 244.6 0.0 2.1e-72 244.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KXL43927.1 - 1.3e-37 129.4 0.0 2.9e-37 128.3 0.1 1.5 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 KXL43927.1 - 6.9e-06 25.5 0.2 0.062 12.5 0.0 3.3 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXL43927.1 - 0.00048 19.8 0.5 0.21 11.1 0.1 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXL43927.1 - 0.0053 17.0 0.0 0.043 14.0 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXL43927.1 - 0.017 15.6 0.0 0.17 12.4 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KXL43927.1 - 0.031 13.8 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.12 KXL43927.1 - 0.15 11.1 0.0 0.3 10.1 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein RabGAP-TBC PF00566.18 KXL43928.1 - 6.6e-38 130.5 0.0 9.8e-38 130.0 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF2956 PF11169.8 KXL43928.1 - 0.032 14.4 0.0 0.065 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) PIR PF00399.19 KXL43929.1 - 1.8e-26 91.1 69.5 2.5e-06 26.9 2.4 7.3 7 0 0 7 7 7 7 Yeast PIR protein repeat Pkinase PF00069.25 KXL43930.1 - 4.9e-32 111.3 0.0 3.9e-19 69.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXL43930.1 - 8.8e-15 54.7 0.0 4.4e-14 52.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase PPR_2 PF13041.6 KXL43931.1 - 0.00095 19.3 0.1 0.0037 17.4 0.0 2.1 3 0 0 3 3 3 1 PPR repeat family PPR_3 PF13812.6 KXL43931.1 - 0.016 15.3 0.0 0.28 11.3 0.0 2.5 2 0 0 2 2 2 0 Pentatricopeptide repeat domain SH3_9 PF14604.6 KXL43933.1 - 2.2e-05 24.2 0.1 6.3e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXL43933.1 - 9.6e-05 21.9 0.2 0.0002 20.9 0.2 1.5 1 0 0 1 1 1 1 SH3 domain PTP_tm PF18861.1 KXL43933.1 - 0.019 15.0 0.1 0.032 14.2 0.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Insulin_TMD PF17870.1 KXL43933.1 - 0.057 13.5 0.0 0.098 12.7 0.0 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF4690 PF15756.5 KXL43933.1 - 0.16 12.6 3.4 0.1 13.2 0.8 2.1 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Hemerythrin PF01814.23 KXL43934.1 - 1.1e-10 42.3 5.8 1.7e-10 41.6 5.8 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF4218 PF13960.6 KXL43934.1 - 0.069 12.8 0.0 2.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4218) Nop53 PF07767.11 KXL43935.1 - 2.3e-95 320.4 17.2 3.4e-95 319.8 17.2 1.3 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF4407 PF14362.6 KXL43935.1 - 0.071 12.5 10.6 0.13 11.6 10.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ras PF00071.22 KXL43936.1 - 1.5e-59 200.2 0.3 1.9e-59 199.9 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXL43936.1 - 1.4e-36 125.3 0.1 2.4e-36 124.6 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXL43936.1 - 3.8e-17 62.3 0.1 4.2e-17 62.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXL43936.1 - 9.8e-06 25.6 0.0 2.5e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXL43936.1 - 1.2e-05 25.2 0.3 0.012 15.6 0.1 2.4 2 1 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KXL43936.1 - 1.5e-05 24.5 0.1 2.4e-05 23.8 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KXL43936.1 - 2.4e-05 24.0 0.1 0.00015 21.4 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KXL43936.1 - 2.9e-05 23.5 0.1 3.5e-05 23.3 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 KXL43936.1 - 0.0028 17.2 0.2 0.076 12.5 0.2 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B TIR_2 PF13676.6 KXL43936.1 - 0.007 17.0 0.0 0.012 16.3 0.0 1.3 1 0 0 1 1 1 1 TIR domain AAA_7 PF12775.7 KXL43936.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TetR_C_16 PF17920.1 KXL43936.1 - 0.14 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain PduV-EutP PF10662.9 KXL43936.1 - 0.17 11.6 0.5 0.7 9.6 0.5 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Kei1 PF08552.11 KXL43937.1 - 1.9e-54 184.5 0.3 2.4e-54 184.1 0.3 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 MAS20 PF02064.15 KXL43938.1 - 3.3e-42 143.6 0.1 3.9e-42 143.4 0.1 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor DUF4129 PF13559.6 KXL43938.1 - 0.045 14.0 1.0 0.42 10.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) DUF429 PF04250.13 KXL43938.1 - 0.099 12.4 4.6 4.6 7.0 3.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF429) DUF5305 PF17231.2 KXL43938.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Exo84_C PF16528.5 KXL43939.1 - 1.3e-48 165.6 0.0 2.8e-48 164.4 0.0 1.6 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 KXL43939.1 - 3.6e-14 52.6 1.7 3.6e-14 52.6 1.7 1.9 2 0 0 2 2 2 1 Vps51/Vps67 IFT57 PF10498.9 KXL43939.1 - 0.0065 15.5 2.1 0.011 14.7 2.1 1.3 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Sec5 PF15469.6 KXL43939.1 - 0.018 14.9 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Exocyst complex component Sec5 DUF563 PF04577.14 KXL43940.1 - 2.5e-33 116.0 0.0 4.5e-33 115.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) VSP PF03302.13 KXL43941.1 - 0.011 14.6 0.2 0.011 14.6 0.2 2.0 2 0 0 2 2 2 0 Giardia variant-specific surface protein FHIPEP PF00771.20 KXL43941.1 - 0.47 8.9 1.0 0.66 8.4 1.0 1.1 1 0 0 1 1 1 0 FHIPEP family DUF3149 PF11346.8 KXL43941.1 - 2.8 7.6 4.1 6 6.6 4.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) TPR_14 PF13428.6 KXL43942.1 - 1.1e-12 47.6 24.5 1.2 10.2 0.0 12.0 10 5 4 14 14 13 4 Tetratricopeptide repeat TPR_8 PF13181.6 KXL43942.1 - 1.8e-10 40.2 6.7 0.083 13.2 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat Suf PF05843.14 KXL43942.1 - 2e-10 41.1 13.0 0.004 17.2 0.2 6.1 4 2 0 4 4 4 3 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.12 KXL43942.1 - 2.7e-06 27.4 12.5 0.19 11.7 0.1 6.7 7 0 0 7 7 7 3 Mad3/BUB1 homology region 1 TPR_15 PF13429.6 KXL43942.1 - 2.7e-06 26.8 1.7 2.7e-06 26.8 1.7 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXL43942.1 - 5e-06 26.2 10.8 0.19 12.0 0.0 7.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXL43942.1 - 4.9e-05 23.7 2.6 1.7 9.2 0.0 6.0 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXL43942.1 - 0.00019 21.7 9.2 22 5.4 0.0 7.2 7 0 0 7 7 7 0 Tetratricopeptide repeat MIT PF04212.18 KXL43942.1 - 0.022 14.8 0.5 0.95 9.6 0.1 3.8 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 KXL43942.1 - 0.063 13.9 4.7 58 4.6 0.0 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXL43942.1 - 0.1 12.5 11.0 2 8.4 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat HAT PF02184.16 KXL43942.1 - 0.91 9.5 12.0 2.3 8.3 0.1 6.3 7 0 0 7 7 7 0 HAT (Half-A-TPR) repeat TPR_17 PF13431.6 KXL43942.1 - 3.5 8.2 9.4 22 5.7 0.1 5.1 7 0 0 7 7 5 0 Tetratricopeptide repeat ATP-synt_D PF01813.17 KXL43943.1 - 1.8e-71 240.0 2.4 2.7e-71 239.5 2.4 1.2 1 0 0 1 1 1 1 ATP synthase subunit D Orthopox_A36R PF05950.11 KXL43943.1 - 0.18 12.0 1.3 0.32 11.1 1.3 1.4 1 0 0 1 1 1 0 Orthopoxvirus A36R protein Mig-14 PF07395.11 KXL43943.1 - 0.44 9.9 3.3 0.13 11.6 0.4 1.5 2 0 0 2 2 2 0 Mig-14 DUF4795 PF16043.5 KXL43943.1 - 0.47 10.0 6.3 2.9 7.5 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) APG6_N PF17675.1 KXL43943.1 - 0.56 10.7 6.1 0.2 12.2 2.5 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region PBP1_TM PF14812.6 KXL43943.1 - 1.1 9.7 11.1 35 4.9 0.0 2.8 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ATP_bind_3 PF01171.20 KXL43944.1 - 3.7e-43 147.4 0.0 6.7e-43 146.6 0.0 1.4 1 0 0 1 1 1 1 PP-loop family Asn_synthase PF00733.21 KXL43944.1 - 0.04 13.6 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase NAD_synthase PF02540.17 KXL43944.1 - 0.079 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 NAD synthase CPSase_L_D2 PF02786.17 KXL43945.1 - 6.2e-115 382.0 0.1 2.2e-84 282.2 0.0 2.5 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.28 KXL43945.1 - 7.9e-48 162.8 0.0 2.3e-47 161.3 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 KXL43945.1 - 8.1e-47 159.0 0.0 2e-46 157.7 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_sm_chain PF00988.22 KXL43945.1 - 4.7e-44 149.3 0.0 1.1e-43 148.2 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain CPSase_L_D3 PF02787.19 KXL43945.1 - 1.9e-39 134.8 0.1 4.1e-39 133.7 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 KXL43945.1 - 3.8e-30 105.0 0.0 9.9e-30 103.7 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Dala_Dala_lig_C PF07478.13 KXL43945.1 - 4.9e-21 75.2 0.2 2.9e-10 40.0 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.22 KXL43945.1 - 1.4e-20 73.3 0.0 8.4e-20 70.8 0.0 2.5 1 0 0 1 1 1 1 MGS-like domain ATP-grasp PF02222.22 KXL43945.1 - 2.2e-18 66.4 0.1 2.7e-09 36.9 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KXL43945.1 - 7.1e-10 38.7 0.0 0.0007 19.3 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 KXL43945.1 - 2.3e-07 31.0 0.1 0.03 14.4 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 KXL43945.1 - 2.8e-05 24.0 0.0 0.33 10.7 0.0 2.9 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Peptidase_C26 PF07722.13 KXL43945.1 - 3.8e-05 23.6 0.2 0.0047 16.7 0.2 2.6 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 KXL43945.1 - 0.00032 20.5 0.0 0.16 11.8 0.0 3.9 4 0 0 4 4 4 1 DJ-1/PfpI family RimK PF08443.11 KXL43945.1 - 0.0097 15.5 0.0 1.4 8.5 0.0 2.5 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 KXL43945.1 - 0.017 14.6 0.0 0.9 8.9 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain MFS_1 PF07690.16 KXL43946.1 - 4.5e-20 71.9 49.5 9.5e-16 57.7 30.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PEN-2 PF10251.9 KXL43946.1 - 0.18 12.2 4.6 0.24 11.8 0.1 3.0 2 1 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase CN_hydrolase PF00795.22 KXL43947.1 - 3.3e-29 102.0 0.0 3.9e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PPR_2 PF13041.6 KXL43948.1 - 3.3e-41 139.2 1.8 1.8e-08 34.4 0.0 13.1 12 3 3 15 15 15 7 PPR repeat family PPR_3 PF13812.6 KXL43948.1 - 3.2e-31 107.2 0.2 0.00029 20.9 0.0 10.3 7 3 3 10 10 10 6 Pentatricopeptide repeat domain PPR_1 PF12854.7 KXL43948.1 - 1.1e-20 73.0 0.1 6.6e-06 25.7 0.0 10.1 11 0 0 11 11 11 3 PPR repeat PPR PF01535.20 KXL43948.1 - 4.2e-19 67.4 28.0 0.0011 19.1 0.1 15.1 18 0 0 18 18 18 4 PPR repeat PPR_long PF17177.4 KXL43948.1 - 1.9e-16 60.1 7.9 7.4e-07 28.7 0.0 6.9 4 2 2 6 6 6 4 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 KXL43948.1 - 1.4e-06 28.7 0.0 8.3e-05 23.0 0.0 3.3 3 0 0 3 3 3 1 Mitochondrial ribonuclease P subunit (RPM2) DUF2052 PF09747.9 KXL43948.1 - 0.29 11.2 0.0 0.29 11.2 0.0 2.0 2 1 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) GHMP_kinases_N PF00288.26 KXL43949.1 - 3.9e-17 62.2 2.8 1.1e-16 60.8 2.8 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KXL43949.1 - 2.6e-10 40.5 0.2 7.4e-10 39.1 0.0 1.9 2 0 0 2 2 2 1 GHMP kinases C terminal RPN13_C PF16550.5 KXL43949.1 - 0.11 12.7 0.0 0.7 10.1 0.0 2.4 2 1 0 2 2 2 0 UCH-binding domain PPP4R2 PF09184.11 KXL43952.1 - 0.092 12.3 4.3 0.15 11.6 4.3 1.3 1 0 0 1 1 1 0 PPP4R2 MFS_1 PF07690.16 KXL43954.1 - 3.8e-23 82.0 31.2 3.8e-23 82.0 31.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily FAD_binding_3 PF01494.19 KXL43955.1 - 5.4e-25 88.4 0.0 6.9e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXL43955.1 - 3.8e-09 36.6 4.6 0.00043 20.0 0.0 2.4 2 1 1 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXL43955.1 - 7.1e-09 35.2 0.2 1.5e-08 34.1 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXL43955.1 - 3.7e-06 26.4 0.1 0.0011 18.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXL43955.1 - 1.8e-05 23.6 0.1 0.0011 17.7 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 KXL43955.1 - 2.3e-05 24.5 0.5 0.00018 21.6 0.4 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KXL43955.1 - 4.5e-05 23.0 0.2 8.3e-05 22.1 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXL43955.1 - 4.5e-05 22.9 0.2 0.0037 16.6 1.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXL43955.1 - 0.00066 19.0 0.1 0.00066 19.0 0.1 1.5 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 KXL43955.1 - 0.0013 18.0 0.0 0.069 12.3 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 KXL43955.1 - 0.0017 17.7 0.1 0.03 13.6 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase GIDA PF01134.22 KXL43955.1 - 0.011 14.9 0.1 0.019 14.1 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 KXL43955.1 - 0.012 14.5 0.1 0.87 8.4 0.0 2.7 3 0 0 3 3 3 0 Tryptophan halogenase Lycopene_cycl PF05834.12 KXL43955.1 - 0.025 13.6 0.9 0.09 11.8 0.9 1.9 1 1 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 KXL43955.1 - 0.04 14.5 0.1 1.5 9.5 0.5 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KXL43955.1 - 0.084 11.9 0.0 0.62 9.1 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase tRNA-synt_2 PF00152.20 KXL43956.1 - 7.2e-74 248.7 0.4 7.2e-74 248.7 0.4 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KXL43956.1 - 6.9e-07 29.2 0.1 8.5e-06 25.7 0.0 2.4 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KXL43956.1 - 1.4e-05 24.7 0.8 0.03 13.8 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) DUF4604 PF15377.6 KXL43956.1 - 0.12 12.8 8.2 1.2 9.5 6.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) SPOC PF07744.13 KXL43957.1 - 1.1e-17 64.3 0.0 1.8e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 KXL43957.1 - 1.4e-16 61.0 1.5 2.7e-16 60.0 1.5 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 KXL43957.1 - 3.6e-09 36.4 8.2 6.8e-09 35.5 8.2 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KXL43957.1 - 0.29 10.7 2.9 0.51 9.9 2.9 1.4 1 0 0 1 1 1 0 PHD-finger Transket_pyr PF02779.24 KXL43958.1 - 5.7e-44 149.9 0.1 8.3e-44 149.4 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KXL43958.1 - 1.7e-33 115.1 0.0 6.7e-33 113.2 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain NTP_transf_6 PF06042.11 KXL43959.1 - 6.9e-52 175.5 0.0 8.4e-52 175.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyltransferase HTH_Tnp_Tc5 PF03221.16 KXL43960.1 - 6e-06 26.2 0.0 6.5e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Arrestin_C PF02752.22 KXL43962.1 - 4e-13 50.0 0.2 8.4e-13 48.9 0.2 1.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KXL43962.1 - 8.4e-08 32.4 0.0 3.3e-06 27.2 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Hormone_6 PF00236.18 KXL43963.1 - 0.0044 17.0 0.4 0.0053 16.7 0.4 1.2 1 0 0 1 1 1 1 Glycoprotein hormone Atx10homo_assoc PF09759.9 KXL43965.1 - 1.7e-21 76.1 0.0 3.1e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain SR-25 PF10500.9 KXL43965.1 - 0.23 11.0 5.6 0.5 9.9 5.6 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PRIMA1 PF16101.5 KXL43965.1 - 0.34 10.9 6.3 0.068 13.2 1.2 2.3 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 PAP1 PF08601.10 KXL43965.1 - 6.2 6.4 10.8 13 5.4 10.8 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 Sulfotransfer_4 PF17784.1 KXL43966.1 - 7.8e-58 195.8 0.1 4.6e-57 193.3 0.1 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXL43966.1 - 4.4e-06 27.2 0.4 0.0015 18.9 0.4 2.3 1 1 0 1 1 1 1 Sulfotransferase family Glyco_hydro_18 PF00704.28 KXL43967.1 - 7e-13 49.0 0.0 1.8e-12 47.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 UBA PF00627.31 KXL43967.1 - 1.1e-05 25.2 0.0 3.8e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 UBA/TS-N domain NIF PF03031.18 KXL43968.1 - 7.1e-36 123.3 0.0 1e-35 122.8 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF2756 PF10956.8 KXL43968.1 - 0.6 10.6 3.5 1.7 9.2 3.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) Glyco_hydro_47 PF01532.20 KXL43969.1 - 1.9e-111 373.2 0.0 2.5e-111 372.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Acetyltransf_10 PF13673.7 KXL43970.1 - 1.6e-07 31.3 0.0 2.9e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXL43970.1 - 2e-07 31.3 0.0 4e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXL43970.1 - 7.6e-06 25.8 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 KXL43970.1 - 0.00013 22.1 0.0 0.00022 21.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KXL43970.1 - 0.00084 19.4 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 KXL43970.1 - 0.16 12.1 0.4 0.41 10.8 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Sulfotransfer_4 PF17784.1 KXL43971.1 - 8.4e-61 205.5 0.1 1e-60 205.2 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXL43971.1 - 0.0075 16.7 0.1 0.02 15.3 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family DUF3328 PF11807.8 KXL43972.1 - 3e-15 56.6 0.7 3e-15 56.6 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Bax1-I PF01027.20 KXL43975.1 - 2.7e-32 112.3 10.8 4.2e-32 111.7 10.8 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Ssu72 PF04722.13 KXL43976.1 - 2e-79 265.6 0.0 2.4e-79 265.4 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein FYVE PF01363.21 KXL43977.1 - 6.3e-21 74.3 2.1 6.3e-21 74.3 2.1 3.0 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 KXL43977.1 - 8.1e-08 32.5 24.4 7.5e-07 29.4 5.0 3.6 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.25 KXL43977.1 - 9.1e-05 22.2 2.6 9.1e-05 22.2 2.6 3.9 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXL43977.1 - 0.00012 21.9 3.8 0.00012 21.9 3.8 4.0 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 KXL43977.1 - 0.00033 20.4 4.7 0.059 13.2 0.8 2.4 2 0 0 2 2 2 2 Rad50 zinc hook motif zf-RING_11 PF17123.5 KXL43977.1 - 0.0015 18.3 6.6 0.0015 18.3 6.6 3.3 4 0 0 4 4 3 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KXL43977.1 - 0.0048 16.9 3.9 0.0048 16.9 3.9 3.8 5 0 0 5 5 4 1 RING-type zinc-finger RNF220 PF15926.5 KXL43977.1 - 0.25 10.9 1.0 0.92 9.1 0.1 2.1 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 Elf1 PF05129.13 KXL43977.1 - 0.6 10.2 6.0 0.39 10.8 0.8 2.5 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like FANCL_C PF11793.8 KXL43977.1 - 0.66 10.2 11.7 0.51 10.6 4.0 3.2 3 0 0 3 3 3 0 FANCL C-terminal domain Opy2 PF09463.10 KXL43977.1 - 0.77 10.1 7.3 0.26 11.6 0.5 3.1 3 0 0 3 3 2 0 Opy2 protein FYVE_2 PF02318.16 KXL43977.1 - 0.83 9.9 9.1 0.12 12.7 1.7 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger zf-piccolo PF05715.13 KXL43977.1 - 1.1 9.4 13.5 0.33 11.1 4.2 3.1 3 0 0 3 3 3 0 Piccolo Zn-finger Prok-RING_1 PF14446.6 KXL43977.1 - 1.7 8.7 22.8 0.49 10.4 3.8 4.3 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 zinc_ribbon_2 PF13240.6 KXL43977.1 - 2.3 8.0 10.2 0.63 9.8 0.2 3.4 3 0 0 3 3 3 0 zinc-ribbon domain DNA_ligase_ZBD PF03119.16 KXL43977.1 - 3.9 7.6 11.8 1.5 8.9 0.8 3.2 3 0 0 3 3 2 0 NAD-dependent DNA ligase C4 zinc finger domain Glyco_hydro_3_C PF01915.22 KXL43978.1 - 1.3e-46 159.1 0.0 2e-46 158.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXL43978.1 - 1.8e-25 90.0 0.0 2.5e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXL43978.1 - 1.9e-09 37.5 0.0 3.8e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Sugar_tr PF00083.24 KXL43979.1 - 2.5e-95 320.0 21.8 3e-95 319.7 21.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL43979.1 - 6e-25 87.9 54.1 3e-22 79.0 30.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CMD PF02627.20 KXL43980.1 - 0.012 15.7 0.0 0.18 11.8 0.0 2.1 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family KIX_2 PF16987.5 KXL43980.1 - 0.067 13.2 0.0 6.4 6.8 0.0 2.5 2 0 0 2 2 2 0 KIX domain adh_short PF00106.25 KXL43981.1 - 7.8e-24 84.2 1.3 1e-22 80.5 1.3 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL43981.1 - 5.1e-20 72.0 0.7 9.6e-19 67.9 0.7 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL43981.1 - 0.0013 18.7 0.4 0.0054 16.6 0.3 1.8 1 1 0 1 1 1 1 KR domain HHH_5 PF14520.6 KXL43981.1 - 0.0018 18.8 0.1 0.0034 17.9 0.1 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain Sugar_tr PF00083.24 KXL43982.1 - 1.7e-99 333.8 22.2 1.9e-99 333.6 22.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL43982.1 - 6.4e-18 64.8 23.3 6.4e-18 64.8 23.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Folate_carrier PF01770.18 KXL43982.1 - 0.84 8.3 9.4 0.25 10.0 3.5 2.1 2 0 0 2 2 2 0 Reduced folate carrier Lactamase_B_6 PF16661.5 KXL43983.1 - 7e-56 188.7 0.0 1.1e-55 188.1 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KXL43983.1 - 4.2e-28 98.6 0.1 4.2e-28 98.6 0.1 3.3 3 1 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 KXL43983.1 - 2.8e-15 56.5 0.0 7.5e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 KXL43983.1 - 1e-08 35.0 0.0 2.5e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Pox_Ag35 PF03286.14 KXL43983.1 - 4.7 6.9 11.4 3.5 7.4 1.8 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CSTF2_hinge PF14327.6 KXL43984.1 - 6.4e-26 90.6 0.5 6.4e-26 90.6 0.5 2.0 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 KXL43984.1 - 1.6e-22 79.1 0.0 2.5e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 KXL43984.1 - 6.8e-09 35.2 2.4 6.8e-09 35.2 2.4 2.3 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_occluded PF16842.5 KXL43984.1 - 0.0015 18.4 0.0 0.0035 17.2 0.0 1.7 1 1 0 1 1 1 1 Occluded RNA-recognition motif RRM_5 PF13893.6 KXL43984.1 - 0.051 13.2 0.0 0.089 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXL43984.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif ABA_WDS PF02496.16 KXL43985.1 - 2.2 8.8 7.6 4.4 7.8 0.2 3.3 3 0 0 3 3 3 0 ABA/WDS induced protein DUF4148 PF13663.6 KXL43985.1 - 3.3 8.0 9.4 33 4.8 6.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Filament PF00038.21 KXL43986.1 - 0.00097 18.8 11.7 0.00097 18.8 11.7 2.3 1 1 1 2 2 2 1 Intermediate filament protein UPF0242 PF06785.11 KXL43986.1 - 0.0032 17.6 12.7 0.0068 16.5 12.7 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF4201 PF13870.6 KXL43986.1 - 0.013 15.2 5.7 0.013 15.2 5.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Cep57_CLD_2 PF14197.6 KXL43986.1 - 0.039 14.0 24.6 0.88 9.7 0.7 5.1 5 0 0 5 5 5 0 Centrosome localisation domain of PPC89 ZapB PF06005.12 KXL43986.1 - 0.071 13.6 26.4 0.13 12.7 1.3 5.8 4 1 2 6 6 5 0 Cell division protein ZapB TACC_C PF05010.14 KXL43986.1 - 0.073 12.9 8.3 0.12 12.1 6.7 2.1 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal YlzJ PF14035.6 KXL43986.1 - 0.082 13.1 0.1 0.56 10.5 0.0 2.3 2 0 0 2 2 2 0 YlzJ-like protein Gp58 PF07902.11 KXL43986.1 - 0.085 11.1 4.4 0.11 10.8 4.4 1.2 1 0 0 1 1 1 0 gp58-like protein FapA PF03961.13 KXL43986.1 - 0.1 11.2 6.2 0.088 11.4 4.2 1.8 2 1 0 2 2 2 0 Flagellar Assembly Protein A Spc7 PF08317.11 KXL43986.1 - 0.19 10.5 19.2 0.69 8.7 6.7 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein BAR_3 PF16746.5 KXL43986.1 - 0.22 11.2 8.3 0.049 13.3 4.9 1.6 2 0 0 2 2 1 0 BAR domain of APPL family Herpes_BLRF2 PF05812.12 KXL43986.1 - 0.31 11.2 7.7 6 7.0 2.2 3.0 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein zf-C4H2 PF10146.9 KXL43986.1 - 0.32 11.3 3.4 0.52 10.6 2.1 2.0 2 0 0 2 2 2 0 Zinc finger-containing protein DUF641 PF04859.12 KXL43986.1 - 0.45 10.8 10.1 2 8.8 2.0 2.9 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) bZIP_1 PF00170.21 KXL43986.1 - 0.53 10.4 6.8 1.3 9.2 0.1 3.4 3 0 0 3 3 2 0 bZIP transcription factor V_ATPase_I PF01496.19 KXL43986.1 - 0.71 7.7 6.4 1 7.2 6.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc42p PF11544.8 KXL43986.1 - 0.87 9.6 5.2 0.53 10.3 0.6 2.9 3 0 0 3 3 3 0 Spindle pole body component Spc42p HIP1_clath_bdg PF16515.5 KXL43986.1 - 1.1 9.9 20.7 0.12 13.0 4.5 3.5 2 1 1 3 3 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 HrpB7 PF09486.10 KXL43986.1 - 1.1 9.6 27.2 0.57 10.5 2.7 4.1 2 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB7) TSC22 PF01166.18 KXL43986.1 - 1.4 9.2 6.2 5.6 7.4 0.1 3.9 4 0 0 4 4 4 0 TSC-22/dip/bun family Rootletin PF15035.6 KXL43986.1 - 2.7 8.0 19.5 2.9 7.9 14.6 3.1 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion YkyA PF10368.9 KXL43986.1 - 3.2 7.4 9.2 22 4.7 9.1 2.4 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein Csm1_N PF18504.1 KXL43986.1 - 3.7 7.9 16.0 2.7 8.4 0.5 4.4 5 0 0 5 5 5 0 Csm1 N-terminal domain PKcGMP_CC PF16808.5 KXL43986.1 - 4.1 7.3 15.9 2.1 8.2 0.2 4.7 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Golgin_A5 PF09787.9 KXL43986.1 - 5.3 6.4 15.1 5.9 6.3 13.3 1.8 1 1 0 1 1 1 0 Golgin subfamily A member 5 FAM76 PF16046.5 KXL43986.1 - 7.4 5.8 7.1 0.75 9.1 1.6 2.1 1 1 2 3 3 3 0 FAM76 protein Pil1 PF13805.6 KXL43987.1 - 1.5e-96 322.9 4.9 1.9e-96 322.6 4.9 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 AF-4 PF05110.13 KXL43988.1 - 0.17 10.0 15.2 0.19 9.8 15.2 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Dsh_C PF12316.8 KXL43988.1 - 0.41 11.0 6.4 0.58 10.5 6.4 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Nop14 PF04147.12 KXL43988.1 - 0.81 7.8 27.7 0.94 7.6 27.7 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KXL43988.1 - 1.7 6.8 25.4 2.6 6.3 25.4 1.2 1 0 0 1 1 1 0 CDC45-like protein FAM60A PF15396.6 KXL43988.1 - 2.2 8.2 14.4 2.8 7.9 14.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Sec62 PF03839.16 KXL43988.1 - 2.4 7.6 13.1 3.2 7.2 13.1 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 TFIIF_alpha PF05793.12 KXL43988.1 - 3 6.3 32.8 3.7 6.0 32.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SLC12 PF03522.15 KXL43988.1 - 5.5 5.9 16.9 6.4 5.7 16.9 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Vfa1 PF08432.10 KXL43988.1 - 6.4 7.1 22.1 8.4 6.7 22.1 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Raftlin PF15250.6 KXL43988.1 - 6.5 5.4 13.1 7.2 5.2 13.1 1.1 1 0 0 1 1 1 0 Raftlin DDRGK PF09756.9 KXL43988.1 - 6.8 6.2 27.7 10 5.7 27.7 1.3 1 0 0 1 1 1 0 DDRGK domain Membralin PF09746.9 KXL43988.1 - 8.5 5.3 7.4 9 5.2 7.4 1.0 1 0 0 1 1 1 0 Tumour-associated protein HTH_38 PF13936.6 KXL43989.1 - 1.7e-10 40.5 0.1 6.2e-10 38.7 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain MarR PF01047.22 KXL43989.1 - 7e-06 25.9 0.0 4.6e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 MarR family HTH_23 PF13384.6 KXL43989.1 - 3.9e-05 23.3 2.0 9.2e-05 22.1 0.1 2.3 3 0 0 3 3 3 1 Homeodomain-like domain HTH_24 PF13412.6 KXL43989.1 - 4.9e-05 22.8 0.1 0.00012 21.5 0.1 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 KXL43989.1 - 0.00016 21.7 0.5 0.00042 20.4 0.5 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 KXL43989.1 - 0.00018 21.7 3.3 0.0006 20.0 0.2 2.6 1 1 0 2 2 2 1 Transposase MarR_2 PF12802.7 KXL43989.1 - 0.00018 21.3 0.0 0.0004 20.2 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_7 PF02796.15 KXL43989.1 - 0.00043 20.3 0.0 0.0073 16.4 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 KXL43989.1 - 0.00054 19.9 1.0 0.0014 18.6 0.2 2.1 2 1 0 2 2 2 1 Winged helix-turn helix HTH_3 PF01381.22 KXL43989.1 - 0.00067 19.7 0.1 0.0036 17.3 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix HTH_Crp_2 PF13545.6 KXL43989.1 - 0.00086 19.2 1.1 0.0023 17.9 0.2 2.0 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain Trp_repressor PF01371.19 KXL43989.1 - 0.001 19.1 0.0 0.0025 17.9 0.0 1.6 1 0 0 1 1 1 1 Trp repressor protein HTH_36 PF13730.6 KXL43989.1 - 0.0018 18.2 0.1 0.0071 16.3 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_Tc3_1 PF11427.8 KXL43989.1 - 0.0023 17.7 0.0 0.0038 17.0 0.0 1.3 1 0 0 1 1 1 1 Tc3 transposase TrmB PF01978.19 KXL43989.1 - 0.006 16.4 0.0 0.018 14.9 0.0 1.8 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Sigma70_r4_2 PF08281.12 KXL43989.1 - 0.0089 15.7 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Fe_dep_repress PF01325.19 KXL43989.1 - 0.013 15.7 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain GntR PF00392.21 KXL43989.1 - 0.016 14.9 0.1 0.06 13.0 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_11 PF08279.12 KXL43989.1 - 0.016 15.1 0.1 0.081 12.9 0.0 2.1 2 0 0 2 2 2 0 HTH domain Rrf2 PF02082.20 KXL43989.1 - 0.019 15.3 0.0 0.45 10.9 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulator HTH_31 PF13560.6 KXL43989.1 - 0.02 15.2 1.2 0.048 14.0 1.2 1.8 1 1 0 1 1 1 0 Helix-turn-helix domain TnsD PF15978.5 KXL43989.1 - 0.056 12.4 0.0 0.063 12.3 0.0 1.2 1 0 0 1 1 1 0 Tn7-like transposition protein D HTH_27 PF13463.6 KXL43989.1 - 0.058 13.9 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_40 PF14493.6 KXL43989.1 - 0.07 13.6 0.0 1.2 9.6 0.1 2.2 1 1 0 1 1 1 0 Helix-turn-helix domain p450 PF00067.22 KXL43990.1 - 4.1e-67 226.9 0.0 5.1e-67 226.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Dor1 PF04124.12 KXL43991.1 - 1.6e-46 158.6 8.4 2.4e-34 118.5 4.8 2.1 2 0 0 2 2 2 2 Dor1-like family GAS PF13851.6 KXL43991.1 - 0.036 13.4 0.6 0.14 11.5 0.0 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Vps51 PF08700.11 KXL43991.1 - 0.078 13.1 0.3 0.29 11.2 0.3 2.0 1 0 0 1 1 1 0 Vps51/Vps67 MeaB PF03308.16 KXL43991.1 - 0.14 11.1 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB UQ_con PF00179.26 KXL43992.1 - 4.9e-19 68.4 0.0 8.4e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF3328 PF11807.8 KXL43994.1 - 8e-15 55.2 0.0 1.1e-14 54.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) HTH_Tnp_Tc5 PF03221.16 KXL43995.1 - 8.9e-05 22.4 0.0 0.00038 20.4 0.0 1.8 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Zn_clus PF00172.18 KXL43996.1 - 1e-06 28.8 11.0 1e-06 28.8 11.0 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXL43996.1 - 0.0033 16.3 4.1 0.02 13.7 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain DUF1892 PF08987.10 KXL43996.1 - 0.054 13.7 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1892) Ribosomal_S2 PF00318.20 KXL43999.1 - 3.4e-26 91.8 0.7 3e-15 56.0 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 KXL43999.1 - 1.2e-08 36.2 9.8 2.4e-08 35.2 9.8 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Ribosomal_S15 PF00312.22 KXL44000.1 - 5.9e-22 77.7 0.1 1.5e-21 76.3 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein S15 RseA_C PF03873.13 KXL44000.1 - 1.6 9.0 6.6 13 6.2 0.0 3.0 3 0 0 3 3 3 0 Anti sigma-E protein RseA, C-terminal domain UQ_con PF00179.26 KXL44001.1 - 2.8e-42 143.7 0.0 3.2e-42 143.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ubiquitin PF00240.23 KXL44002.1 - 0.00024 20.8 0.0 0.00035 20.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 KXL44002.1 - 0.0025 18.5 0.0 0.0041 17.8 0.0 1.4 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD adh_short PF00106.25 KXL44003.1 - 1e-22 80.6 0.1 2.1e-18 66.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXL44003.1 - 7.8e-12 45.3 0.0 1.4e-10 41.1 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL44003.1 - 6e-07 29.5 0.2 1.1e-06 28.8 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL44003.1 - 0.12 11.8 0.1 0.23 10.9 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltr_RsmB-F PF01189.17 KXL44004.1 - 1.4e-36 126.0 0.0 1.9e-29 102.7 0.0 3.2 1 1 1 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KXL44004.1 - 0.061 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase FoP_duplication PF13865.6 KXL44004.1 - 0.13 12.9 14.0 0.27 11.8 14.0 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Glyco_hydro_72 PF03198.14 KXL44006.1 - 5.6e-102 341.2 0.1 7.8e-102 340.7 0.1 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.17 KXL44006.1 - 0.12 11.4 0.0 0.38 9.8 0.0 1.7 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Pkinase PF00069.25 KXL44007.1 - 2.6e-13 49.9 0.0 1.9e-12 47.1 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL44007.1 - 1.2e-07 31.4 0.0 6.1e-07 29.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase PGF-CTERM PF18204.1 KXL44008.1 - 0.74 9.9 4.1 1.4 9.0 4.1 1.5 1 0 0 1 1 1 0 PGF-CTERM motif MFS_1 PF07690.16 KXL44009.1 - 1.4e-27 96.6 65.3 7.6e-27 94.2 47.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C2H2 PF00096.26 KXL44010.1 - 1.6e-08 34.5 7.4 5.4e-05 23.4 0.8 2.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXL44010.1 - 1.4e-07 31.8 1.0 0.0007 20.2 0.3 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 KXL44010.1 - 0.00033 20.9 0.7 0.00048 20.4 0.7 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 KXL44010.1 - 0.0005 20.4 5.4 0.17 12.4 0.8 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_12 PF18658.1 KXL44010.1 - 0.0055 16.2 0.2 0.0081 15.7 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger C2H2-type zf-BED PF02892.15 KXL44010.1 - 0.027 14.5 0.9 0.058 13.4 0.9 1.5 1 1 0 1 1 1 0 BED zinc finger zf-C2H2_11 PF16622.5 KXL44010.1 - 0.081 12.7 0.3 0.42 10.4 0.1 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type zf_ZIC PF18366.1 KXL44010.1 - 0.18 11.9 2.2 0.91 9.7 0.0 2.3 1 1 1 2 2 2 0 Zic proteins zinc finger domain zf-H2C2_5 PF13909.6 KXL44010.1 - 2.6 7.9 6.6 1.9 8.3 0.2 2.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Retrotran_gag_3 PF14244.6 KXL44012.1 - 0.00063 19.5 0.0 0.00098 18.9 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type 4HBT PF03061.22 KXL44013.1 - 6.4e-11 42.5 0.0 1e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KXL44013.1 - 0.0018 18.6 0.0 0.0024 18.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily EamA PF00892.20 KXL44014.1 - 7.4e-23 81.2 28.7 7.9e-13 48.7 14.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF2070 PF09843.9 KXL44014.1 - 0.072 11.4 8.4 0.069 11.4 7.7 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) Glyco_hydro_76 PF03663.14 KXL44015.1 - 4.8e-29 102.0 24.6 6e-29 101.7 24.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KXL44015.1 - 0.00015 21.0 1.9 0.0069 15.5 0.0 2.8 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 KXL44015.1 - 0.00065 19.2 2.2 1.7 8.1 0.0 3.7 3 1 1 4 4 4 2 D-glucuronyl C5-epimerase C-terminus HMA PF00403.26 KXL44016.1 - 1.5e-16 60.6 2.1 1.7e-16 60.4 2.1 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Ribosomal_S8 PF00410.19 KXL44016.1 - 0.016 15.1 0.1 0.018 15.0 0.1 1.0 1 0 0 1 1 1 0 Ribosomal protein S8 Dodecin PF07311.12 KXL44016.1 - 0.057 13.7 0.1 0.088 13.1 0.1 1.4 1 0 0 1 1 1 0 Dodecin DUF211 PF02680.14 KXL44016.1 - 0.063 13.4 0.2 0.076 13.2 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 Thiolase_N PF00108.23 KXL44017.1 - 7.4e-14 51.7 0.2 5.2e-12 45.7 0.1 2.9 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXL44017.1 - 2.9e-13 49.6 1.3 1.2e-11 44.3 0.1 3.0 1 1 2 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KXL44017.1 - 3.3e-05 23.7 0.1 0.0013 18.6 0.0 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 KXL44017.1 - 0.0011 18.6 0.1 0.0022 17.6 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 KXL44017.1 - 0.0064 15.2 0.4 0.029 13.1 0.1 1.9 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) Ketoacyl-synt_C PF02801.22 KXL44017.1 - 0.052 13.6 0.9 15 5.6 0.0 3.3 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain SmaI PF17411.2 KXL44017.1 - 0.15 11.2 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 Type II site-specific deoxyribonuclease NMT1 PF09084.11 KXL44020.1 - 8.1e-23 81.5 0.0 9.6e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like MFS_1 PF07690.16 KXL44021.1 - 1.1e-33 116.6 30.2 1.1e-33 116.6 30.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF973 PF06157.11 KXL44021.1 - 0.023 13.8 0.9 0.049 12.7 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF1129 PF06570.11 KXL44021.1 - 2.1 7.8 12.7 6.1 6.3 5.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) PsbN PF02468.15 KXL44021.1 - 9.9 6.1 6.4 3.5 7.6 0.7 2.8 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) RasGEF PF00617.19 KXL44022.1 - 1.1e-50 172.2 0.1 5.5e-50 170.0 0.0 2.2 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KXL44022.1 - 5.8e-15 55.4 0.0 2.2e-14 53.6 0.0 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 KXL44022.1 - 4.6e-05 22.9 0.0 0.00012 21.6 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXL44022.1 - 0.00014 21.6 0.0 0.00047 20.0 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain DUF2408 PF10303.9 KXL44022.1 - 0.0022 18.6 0.1 0.014 16.0 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2408) SH3_2 PF07653.17 KXL44022.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain zf-CHY PF05495.12 KXL44023.1 - 2.4e-18 66.4 19.7 2.4e-18 66.4 19.7 4.0 3 1 1 4 4 4 1 CHY zinc finger zinc_ribbon_6 PF14599.6 KXL44023.1 - 6.5e-18 64.5 2.7 4.9e-15 55.3 0.3 6.0 4 2 1 5 5 5 3 Zinc-ribbon zf-RING_2 PF13639.6 KXL44023.1 - 3.4e-08 33.7 4.0 3.4e-08 33.7 4.0 5.4 2 2 4 6 6 6 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXL44023.1 - 7.5e-05 22.5 6.7 7.5e-05 22.5 6.7 6.6 6 2 2 8 8 8 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXL44023.1 - 0.0048 16.6 0.9 0.0048 16.6 0.9 4.6 7 0 0 7 7 7 1 RING-like zinc finger zf-RING_5 PF14634.6 KXL44023.1 - 0.0064 16.4 12.9 0.0064 16.4 12.9 6.7 3 3 1 5 5 5 1 zinc-RING finger domain Sec23_trunk PF04811.15 KXL44024.1 - 1e-74 251.2 0.0 1.5e-74 250.6 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KXL44024.1 - 1.3e-28 99.6 0.0 3.5e-28 98.2 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KXL44024.1 - 4.2e-24 84.3 0.6 1e-23 83.1 0.1 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KXL44024.1 - 9.4e-16 57.6 7.0 1.7e-15 56.8 7.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KXL44024.1 - 1.3e-11 44.2 0.0 2.7e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KXL44024.1 - 0.15 11.5 0.6 0.34 10.3 0.2 1.7 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Aa_trans PF01490.18 KXL44025.1 - 5.7e-70 236.1 21.0 7e-70 235.8 21.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KXL44025.1 - 0.0031 16.6 14.3 0.0031 16.6 14.3 2.0 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family Ecl1 PF12855.7 KXL44027.1 - 1.9e-13 52.0 22.9 2.2e-13 51.8 22.9 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins YacG PF03884.14 KXL44027.1 - 0.03 14.0 0.7 0.078 12.7 0.7 1.6 1 0 0 1 1 1 0 DNA gyrase inhibitor YacG Flavi_NS4A PF01350.17 KXL44029.1 - 0.041 13.8 0.1 0.048 13.6 0.1 1.2 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A 4HBT_3 PF13622.6 KXL44030.1 - 3.9e-26 92.8 0.0 5.3e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KXL44030.1 - 9.9e-08 31.9 0.3 0.032 14.1 0.1 3.1 2 1 0 2 2 2 2 Acyl-CoA thioesterase Sugar_tr PF00083.24 KXL44031.1 - 1.5e-100 337.2 26.9 1.7e-100 337.0 26.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL44031.1 - 4.6e-22 78.4 35.2 1.4e-17 63.7 8.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily COX7a PF02238.15 KXL44031.1 - 0.76 10.2 3.0 17 5.9 0.0 3.5 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VII Ribosomal_S6 PF01250.17 KXL44032.1 - 5.9e-26 90.6 0.0 7.1e-26 90.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 GCV_H PF01597.19 KXL44034.1 - 1.3e-39 134.9 0.6 1.5e-39 134.7 0.6 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 KXL44034.1 - 0.0036 17.2 0.2 0.0052 16.7 0.2 1.2 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 KXL44034.1 - 0.006 16.4 0.6 0.014 15.2 0.3 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme MCR_alpha PF02249.17 KXL44034.1 - 0.099 13.1 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain Apc13p PF05839.11 KXL44035.1 - 1.8e-30 105.0 0.1 2e-30 104.8 0.1 1.0 1 0 0 1 1 1 1 Apc13p protein Ribosomal_S14 PF00253.21 KXL44036.1 - 4.7e-14 51.9 4.1 5.3e-14 51.7 4.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Nup192 PF11894.8 KXL44037.1 - 1.4e-299 997.2 0.0 1.7e-299 996.9 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 PI3_PI4_kinase PF00454.27 KXL44038.1 - 4.5e-56 190.4 0.1 3.8e-54 184.1 0.0 2.9 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 KXL44038.1 - 2.3e-41 141.4 8.4 4.4e-41 140.5 0.0 4.2 4 0 0 4 4 4 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 KXL44038.1 - 5.1e-11 42.2 0.2 1.3e-10 40.9 0.2 1.7 1 0 0 1 1 1 1 FATC domain Vps53_N PF04100.12 KXL44038.1 - 0.083 11.8 1.2 1.7 7.5 0.0 2.5 2 0 0 2 2 2 0 Vps53-like, N-terminal Telomere_reg-2 PF10193.9 KXL44038.1 - 0.25 11.8 1.8 2.4 8.6 0.2 3.7 3 0 0 3 3 3 0 Telomere length regulation protein IF-2B PF01008.17 KXL44039.1 - 9.6e-76 254.7 0.0 1.2e-75 254.3 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF5549 PF17703.1 KXL44039.1 - 0.23 11.1 2.9 0.55 9.9 2.9 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5549) Glyco_hydro_28 PF00295.17 KXL44040.1 - 3.9e-39 134.6 10.7 5.5e-38 130.8 6.2 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 28 DUF4598 PF15370.6 KXL44041.1 - 5.4e-07 30.1 0.3 5.4e-07 30.1 0.3 3.4 2 2 0 2 2 1 1 Domain of unknown function (DUF4598) SR-25 PF10500.9 KXL44041.1 - 0.0013 18.4 12.9 0.0019 17.9 12.9 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SPX PF03105.19 KXL44041.1 - 0.0083 16.1 2.1 0.0083 16.1 2.1 1.2 1 0 0 1 1 1 1 SPX domain Presenilin PF01080.17 KXL44041.1 - 0.19 10.5 1.4 0.19 10.5 1.4 1.1 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 KXL44041.1 - 0.23 10.3 2.2 0.22 10.3 2.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Myc_N PF01056.18 KXL44041.1 - 0.34 10.8 7.3 0.5 10.2 7.3 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Macoilin PF09726.9 KXL44041.1 - 0.75 8.3 2.6 0.84 8.1 2.6 1.0 1 0 0 1 1 1 0 Macoilin family NOA36 PF06524.12 KXL44041.1 - 0.98 8.7 8.9 1.6 8.0 8.9 1.3 1 0 0 1 1 1 0 NOA36 protein DUF4746 PF15928.5 KXL44041.1 - 1.7 8.0 5.7 2.2 7.6 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PPP4R2 PF09184.11 KXL44041.1 - 2.4 7.7 11.7 3.6 7.1 11.7 1.2 1 0 0 1 1 1 0 PPP4R2 RNA_pol_3_Rpc31 PF11705.8 KXL44041.1 - 5.4 7.2 12.6 0.83 9.9 8.4 1.7 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.12 KXL44041.1 - 5.6 5.1 10.3 7.1 4.7 10.3 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 KXL44041.1 - 5.7 6.6 13.1 10 5.8 13.1 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein IF4E PF01652.18 KXL44042.1 - 5.3e-37 127.1 0.0 6.8e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Cadherin_C PF01049.17 KXL44042.1 - 0.13 12.6 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Cadherin cytoplasmic region Plavaka PF18759.1 KXL44042.1 - 0.2 10.8 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Plavaka transposase Porphobil_deam PF01379.20 KXL44043.1 - 1e-71 240.6 0.0 1.6e-71 240.0 0.0 1.3 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KXL44043.1 - 7e-18 64.8 0.1 1.6e-17 63.7 0.1 1.6 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain DUF4805 PF16063.5 KXL44043.1 - 0.096 12.0 2.4 0.078 12.3 0.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4805) Glyco_transf_15 PF01793.16 KXL44044.1 - 5.9e-98 328.1 6.9 2e-65 221.2 1.0 2.1 2 0 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase ADH_N PF08240.12 KXL44045.1 - 1.7e-25 89.0 2.6 2.7e-25 88.4 2.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXL44045.1 - 2.7e-14 53.3 0.0 1.2e-13 51.1 0.0 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXL44045.1 - 3.1e-05 25.0 0.0 4.9e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_8 PF13450.6 KXL44046.1 - 4.4e-06 26.8 0.0 1.7e-05 25.0 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KXL44046.1 - 6.8e-05 22.3 0.0 0.13 11.5 0.0 2.7 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 KXL44046.1 - 0.011 15.4 0.0 1.8 8.1 0.0 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXL44046.1 - 0.031 14.8 0.1 0.088 13.4 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXL44046.1 - 0.044 13.0 0.0 0.2 10.9 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4131 PF13567.6 KXL44047.1 - 0.16 11.6 0.5 1.5 8.4 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF3237 PF11578.8 KXL44048.1 - 0.00043 20.2 0.0 0.00046 20.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) DnaJ PF00226.31 KXL44050.1 - 1e-19 70.4 0.5 1.8e-19 69.6 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain DUF3552 PF12072.8 KXL44051.1 - 0.085 12.3 18.6 0.1 12.0 18.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) MFS_1 PF07690.16 KXL44053.1 - 9.5e-16 57.7 31.4 1.3e-15 57.2 31.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL44053.1 - 1.5e-08 33.9 8.6 1.5e-08 33.9 8.6 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter PhyH PF05721.13 KXL44054.1 - 5.5e-11 43.1 0.0 1e-10 42.2 0.0 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KXL44054.1 - 0.005 17.2 0.0 0.012 16.1 0.0 1.7 1 1 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase PQ-loop PF04193.14 KXL44055.1 - 1.1e-38 130.8 3.3 3.7e-18 65.1 2.1 2.7 2 0 0 2 2 2 2 PQ loop repeat DUF5571 PF17732.1 KXL44055.1 - 0.091 12.2 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5571) ER_lumen_recept PF00810.18 KXL44055.1 - 0.1 13.4 0.0 2.7 8.8 0.0 2.4 2 0 0 2 2 2 0 ER lumen protein retaining receptor Sugar_tr PF00083.24 KXL44056.1 - 8.3e-120 400.7 28.8 9.4e-120 400.5 28.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL44056.1 - 1.7e-22 79.8 35.8 1.7e-22 79.8 35.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4188 PF13826.6 KXL44057.1 - 6.3e-24 84.6 1.7 9.6e-24 84.0 1.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) PAN_4 PF14295.6 KXL44059.1 - 0.0014 18.4 1.0 0.0026 17.6 1.0 1.4 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 KXL44059.1 - 0.0017 18.3 1.2 0.0025 17.7 1.2 1.3 1 0 0 1 1 1 1 PAN domain EFF-AFF PF14884.6 KXL44059.1 - 0.075 11.2 1.0 0.092 10.8 1.0 1.1 1 0 0 1 1 1 0 Type I membrane glycoproteins cell-cell fusogen Metal_resist PF13801.6 KXL44059.1 - 0.26 11.5 0.1 0.36 11.0 0.1 1.2 1 0 0 1 1 1 0 Heavy-metal resistance CDH-cyt PF16010.5 KXL44061.1 - 4.1e-11 42.9 0.0 1.1e-10 41.4 0.0 1.7 1 1 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DUF2427 PF10348.9 KXL44061.1 - 0.00032 20.4 0.2 0.00078 19.2 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) rRNA_proc-arch PF13234.6 KXL44062.1 - 2.2 8.2 17.2 0.34 10.8 2.4 4.2 4 0 0 4 4 4 0 rRNA-processing arch domain CpxA_peri PF16527.5 KXL44062.1 - 3.1 8.2 8.2 5.3 7.4 1.5 3.6 4 0 0 4 4 4 0 Two-component sensor protein CpxA, periplasmic domain WD40_alt PF14077.6 KXL44062.1 - 3.3 7.6 8.4 11 6.0 0.4 4.9 4 0 0 4 4 4 0 Alternative WD40 repeat motif Pkinase PF00069.25 KXL44063.1 - 1.2e-68 231.4 0.0 2.1e-68 230.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL44063.1 - 5.1e-38 130.8 0.0 8.9e-38 130.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXL44063.1 - 0.0016 17.3 0.0 0.003 16.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXL44063.1 - 0.0034 17.3 0.0 0.007 16.3 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXL44063.1 - 0.0084 15.5 0.0 0.021 14.2 0.0 1.6 1 0 0 1 1 1 1 Kinase-like TACC_C PF05010.14 KXL44063.1 - 0.034 13.9 1.7 0.08 12.7 1.7 1.6 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Seadorna_VP7 PF07387.11 KXL44063.1 - 0.04 13.0 0.0 0.11 11.5 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 Acyl-CoA_dh_1 PF00441.24 KXL44064.1 - 4.7e-29 101.5 2.1 6.6e-29 101.1 2.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXL44064.1 - 8.1e-23 80.5 0.1 1.5e-22 79.6 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KXL44064.1 - 6.8e-19 68.6 0.0 1.5e-18 67.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Ecm29 PF13001.7 KXL44064.1 - 0.29 9.8 0.0 0.46 9.1 0.0 1.2 1 0 0 1 1 1 0 Proteasome stabiliser His_Phos_2 PF00328.22 KXL44065.1 - 1.9e-43 149.3 0.0 2.3e-43 149.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Catalase PF00199.19 KXL44067.1 - 0.081 12.0 0.0 0.095 11.8 0.0 1.1 1 0 0 1 1 1 0 Catalase DUF1774 PF08611.10 KXL44068.1 - 2.5e-34 117.5 4.3 2.5e-34 117.5 4.3 2.1 3 0 0 3 3 3 1 Fungal protein of unknown function (DUF1774) DUF4231 PF14015.6 KXL44068.1 - 0.037 14.5 2.9 0.16 12.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF5362 PF17319.2 KXL44068.1 - 8.6 6.3 12.7 0.051 13.4 2.0 2.8 3 1 0 3 3 3 0 Family of unknown function (DUF5362) zf-H2C2_2 PF13465.6 KXL44069.1 - 0.016 15.6 2.0 0.036 14.5 0.4 2.3 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.26 KXL44069.1 - 0.041 14.4 6.1 0.093 13.2 2.0 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type Band_7 PF01145.25 KXL44070.1 - 3.3e-30 105.4 0.3 6.3e-30 104.5 0.3 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 KXL44070.1 - 4.4e-23 81.1 0.3 1.2e-22 79.7 0.3 1.8 1 0 0 1 1 1 1 C-terminal region of band_7 Pox_A11 PF05061.13 KXL44070.1 - 0.04 13.2 0.3 0.095 12.0 0.2 1.7 2 0 0 2 2 2 0 Poxvirus A11 Protein Ribosomal_L10 PF00466.20 KXL44071.1 - 0.0019 18.3 0.0 0.018 15.2 0.0 2.1 2 1 0 2 2 2 1 Ribosomal protein L10 Glycos_transf_3 PF00591.21 KXL44072.1 - 3.2e-55 187.5 0.0 6.1e-55 186.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KXL44072.1 - 5.3e-11 42.2 0.1 1.3e-10 41.0 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain DUF2755 PF10954.8 KXL44073.1 - 0.11 12.4 0.2 0.25 11.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2755) DUF4448 PF14610.6 KXL44073.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) TMEM154 PF15102.6 KXL44073.1 - 3.5 7.5 5.3 0.33 10.9 0.1 1.9 3 0 0 3 3 3 0 TMEM154 protein family V-ATPase_H_N PF03224.14 KXL44074.1 - 9.6e-77 258.4 1.6 1.2e-76 258.0 1.6 1.1 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 KXL44074.1 - 1.7e-36 124.9 0.5 1.5e-35 121.8 0.0 2.6 3 0 0 3 3 3 1 V-ATPase subunit H RIX1 PF08167.12 KXL44074.1 - 0.0032 17.2 3.5 0.095 12.4 0.0 3.2 3 1 1 4 4 4 2 rRNA processing/ribosome biogenesis KIAA1430 PF13879.6 KXL44074.1 - 0.33 11.7 2.1 0.4 11.4 0.0 2.3 3 0 0 3 3 3 0 KIAA1430 homologue Sterol-sensing PF12349.8 KXL44075.1 - 1.5e-37 128.8 9.9 1.5e-37 128.8 9.9 2.5 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KXL44075.1 - 1.3e-13 50.0 3.1 2e-13 49.4 3.1 1.2 1 0 0 1 1 1 1 Patched family Crystall_3 PF08964.10 KXL44075.1 - 0.12 12.5 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Beta/Gamma crystallin PI_PP_I PF18363.1 KXL44076.1 - 0.12 12.5 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoinositide phosphatase insertion domain Macoilin PF09726.9 KXL44076.1 - 3.2 6.2 5.6 3.8 5.9 5.6 1.1 1 0 0 1 1 1 0 Macoilin family CorA PF01544.18 KXL44077.1 - 8.9e-08 31.8 4.8 3.7e-05 23.2 1.3 2.4 1 1 1 2 2 2 2 CorA-like Mg2+ transporter protein SieB PF14163.6 KXL44077.1 - 2.8 7.4 4.7 4.4 6.8 3.5 1.9 2 0 0 2 2 2 0 Super-infection exclusion protein B Acetyltransf_1 PF00583.25 KXL44078.1 - 2.6e-10 40.6 0.0 3.7e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXL44078.1 - 2.7e-09 37.0 0.0 5e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXL44078.1 - 2.6e-07 31.0 0.0 4.6e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXL44078.1 - 0.0029 17.5 0.0 0.0067 16.4 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KXL44078.1 - 0.0036 17.4 0.0 0.0069 16.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 KXL44078.1 - 0.18 11.8 0.2 0.74 9.8 0.0 2.2 2 1 0 2 2 2 0 ESCO1/2 acetyl-transferase Ribosomal_L1 PF00687.21 KXL44079.1 - 1.3e-46 159.0 0.3 1.4e-46 158.8 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Rcd1 PF04078.13 KXL44080.1 - 1.7e-125 417.5 2.8 2e-125 417.3 2.8 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like HET PF06985.11 KXL44081.1 - 1.5e-07 31.9 0.0 1.6e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DNA_ligase_A_M PF01068.21 KXL44083.1 - 6.9e-59 198.9 0.4 2.5e-46 157.9 0.2 2.4 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KXL44083.1 - 1.4e-42 145.9 0.1 3e-42 144.9 0.1 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KXL44083.1 - 2.9e-27 95.2 0.0 1.2e-26 93.2 0.0 2.2 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.6 KXL44083.1 - 0.11 12.6 0.1 10 6.2 0.1 2.8 2 0 0 2 2 2 0 DNA ligase OB-like domain Rrp15p PF07890.12 KXL44083.1 - 0.16 12.3 5.9 0.67 10.3 5.9 2.1 1 0 0 1 1 1 0 Rrp15p Adeno_E1B_55K_N PF04623.12 KXL44083.1 - 0.24 12.1 0.0 0.24 12.1 0.0 2.6 3 0 0 3 3 3 0 Adenovirus E1B protein N-terminus Cid2 PF09774.9 KXL44084.1 - 2e-51 174.6 0.0 2.4e-51 174.3 0.0 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 DUF1635 PF07795.11 KXL44085.1 - 0.0029 17.5 0.1 0.0043 16.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1635) LEA_5 PF00477.17 KXL44085.1 - 0.13 12.8 2.1 0.19 12.2 0.2 2.1 2 1 0 2 2 2 0 Small hydrophilic plant seed protein Mob1_phocein PF03637.17 KXL44086.1 - 4.9e-43 147.1 0.1 8e-43 146.4 0.1 1.3 1 1 0 1 1 1 1 Mob1/phocein family Leo1 PF04004.13 KXL44087.1 - 8.4e-36 123.3 1.0 1.5e-35 122.5 0.0 1.9 2 0 0 2 2 2 1 Leo1-like protein Arf PF00025.21 KXL44088.1 - 6.6e-80 266.7 0.1 7.7e-80 266.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KXL44088.1 - 3e-14 53.2 0.0 4.3e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KXL44088.1 - 5.1e-14 52.1 0.0 6.2e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KXL44088.1 - 2.5e-13 49.9 1.4 2e-09 37.1 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KXL44088.1 - 8.2e-13 48.3 0.0 8.9e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KXL44088.1 - 1.7e-10 40.7 0.0 2.1e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXL44088.1 - 4.1e-06 26.8 0.0 6.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KXL44088.1 - 0.011 15.1 0.7 0.026 13.8 0.7 1.7 1 1 0 1 1 1 0 6-phosphofructo-2-kinase SnoaL_2 PF12680.7 KXL44089.1 - 6.7e-06 26.7 0.2 1.2e-05 25.9 0.2 1.4 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 KXL44089.1 - 0.0002 21.1 0.0 0.00034 20.4 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase MFS_1 PF07690.16 KXL44090.1 - 4.6e-33 114.6 54.4 9.3e-33 113.6 53.7 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily YqzM PF14141.6 KXL44090.1 - 9.6 6.3 9.2 1.3 9.1 3.2 2.7 2 0 0 2 2 2 0 YqzM-like protein p450 PF00067.22 KXL44091.1 - 1.8e-56 191.8 0.0 2e-56 191.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2615 PF11027.8 KXL44091.1 - 0.16 12.1 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) FAA_hydrolase PF01557.18 KXL44092.1 - 6.9e-55 186.1 0.0 9.8e-55 185.6 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KXL44092.1 - 1.3e-32 112.1 0.0 2.8e-32 111.1 0.0 1.5 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal P22_CoatProtein PF11651.8 KXL44092.1 - 0.08 11.5 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 P22 coat protein - gene protein 5 HgmA PF04209.13 KXL44093.1 - 6e-198 657.8 0.2 6.9e-198 657.6 0.2 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase SLD3 PF08639.10 KXL44094.1 - 2.9e-126 422.4 16.2 4.5e-126 421.8 16.2 1.3 1 0 0 1 1 1 1 DNA replication regulator SLD3 Abhydrolase_6 PF12697.7 KXL44096.1 - 2.7e-09 38.0 0.0 1.3e-08 35.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXL44096.1 - 2e-05 24.0 0.0 3.2e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Tocopherol_cycl PF14249.6 KXL44097.1 - 3.6e-05 23.1 0.0 0.0024 17.0 0.0 2.8 2 2 0 2 2 2 2 Tocopherol cyclase Arginase PF00491.21 KXL44099.1 - 4.1e-92 308.6 0.0 5.4e-92 308.2 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KXL44099.1 - 0.014 15.6 0.6 0.028 14.6 0.3 1.6 1 1 0 1 1 1 0 UPF0489 domain Fapy_DNA_glyco PF01149.24 KXL44100.1 - 4.3e-28 98.2 0.0 1.2e-27 96.8 0.0 1.7 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 KXL44100.1 - 5.9e-22 77.5 0.0 9.5e-22 76.8 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 KXL44100.1 - 0.007 15.2 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) NARP1 PF12569.8 KXL44101.1 - 6.4e-184 612.7 27.3 2.2e-181 604.3 20.5 2.5 2 1 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.6 KXL44101.1 - 1.4e-19 70.4 29.6 0.00011 22.6 1.0 7.8 7 1 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 KXL44101.1 - 6.5e-18 63.3 40.9 2.6e-05 24.0 0.4 12.1 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_16 PF13432.6 KXL44101.1 - 1.5e-17 63.9 37.7 9.2e-05 23.0 0.6 8.8 10 1 0 10 10 7 6 Tetratricopeptide repeat TPR_14 PF13428.6 KXL44101.1 - 1.2e-15 56.8 34.3 0.0029 18.3 0.3 11.7 7 4 5 12 12 11 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXL44101.1 - 3e-13 48.8 23.8 8.2e-05 22.5 0.2 9.1 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_1 PF00515.28 KXL44101.1 - 9e-13 47.4 30.3 1.8e-06 27.5 0.7 9.5 9 0 0 9 9 9 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KXL44101.1 - 1.9e-12 47.2 20.4 4.2e-06 26.9 3.0 4.9 4 1 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KXL44101.1 - 7.2e-11 41.6 12.8 8.8e-08 31.7 0.3 5.8 6 0 0 6 6 5 2 TPR repeat TPR_9 PF13371.6 KXL44101.1 - 1.3e-08 34.8 18.6 0.00049 20.2 0.9 6.9 5 3 2 7 7 7 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXL44101.1 - 1.6e-05 24.9 8.1 0.73 9.9 0.1 5.0 4 0 0 4 4 4 3 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 KXL44101.1 - 0.00016 21.9 37.3 0.021 15.1 0.3 9.2 8 3 0 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXL44101.1 - 0.0004 20.8 17.8 0.58 10.9 0.2 7.3 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_3 PF07720.12 KXL44101.1 - 0.0007 19.5 0.3 0.037 14.0 0.3 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.14 KXL44101.1 - 0.019 15.5 7.5 2.4 9.0 0.2 5.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KXL44101.1 - 0.041 14.3 18.5 4.1 8.0 0.2 7.3 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXL44101.1 - 0.096 12.8 11.7 0.89 9.7 0.2 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat GN3L_Grn1 PF08701.11 KXL44102.1 - 2.5e-25 88.4 17.3 4.2e-25 87.6 16.7 1.7 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase DUF559 PF04480.12 KXL44102.1 - 0.033 14.0 0.1 0.055 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF559) HET PF06985.11 KXL44104.1 - 1.9e-23 83.4 1.2 2.2e-23 83.2 0.4 1.5 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) ACPS PF01648.20 KXL44105.1 - 4.1e-08 33.3 0.1 2.7e-07 30.7 0.1 2.1 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily WHAMM-JMY_N PF15920.5 KXL44105.1 - 0.018 14.9 0.5 0.065 13.1 0.1 2.1 2 0 0 2 2 2 0 N-terminal of Junction-mediating and WASP homolog-associated NUDIX PF00293.28 KXL44106.1 - 1.3e-16 60.8 1.4 6.5e-16 58.6 0.1 2.3 1 1 2 3 3 3 1 NUDIX domain MFS_1 PF07690.16 KXL44108.1 - 1.7e-16 60.1 45.3 4.3e-16 58.8 41.2 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXL44108.1 - 5.5e-07 28.4 12.5 9e-07 27.7 12.5 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Neurensin PF14927.6 KXL44108.1 - 7.4 6.3 6.6 1.8 8.2 0.0 3.1 3 1 0 4 4 4 0 Neurensin DUF1180 PF06679.12 KXL44109.1 - 0.002 18.6 0.5 0.0027 18.1 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) Pkinase PF00069.25 KXL44111.1 - 2.1e-70 237.1 0.0 3.1e-70 236.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL44111.1 - 2.9e-39 134.9 0.0 7.5e-39 133.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KXL44111.1 - 7.9e-19 67.2 0.1 1.3e-18 66.5 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 KXL44111.1 - 3.4e-05 23.3 0.0 0.00011 21.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KXL44111.1 - 5.7e-05 22.6 0.1 0.00011 21.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXL44111.1 - 0.00024 20.2 0.0 0.00036 19.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KXL44111.1 - 0.00028 20.9 1.4 0.055 13.4 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family WaaY PF06176.11 KXL44111.1 - 0.044 13.4 0.1 0.068 12.8 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.22 KXL44111.1 - 0.19 11.3 0.1 0.35 10.4 0.1 1.3 1 0 0 1 1 1 0 RIO1 family DUF1604 PF07713.13 KXL44112.1 - 1.6e-33 114.4 2.1 2.3e-33 113.8 0.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.23 KXL44112.1 - 7.5e-06 25.7 0.8 7.5e-06 25.7 0.8 3.2 4 0 0 4 4 4 1 G-patch domain G-patch_2 PF12656.7 KXL44112.1 - 0.014 15.5 4.9 0.85 9.8 4.9 3.1 1 1 0 1 1 1 0 G-patch domain MFS_1 PF07690.16 KXL44113.1 - 3e-20 72.4 56.9 1.9e-10 40.2 31.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXL44113.1 - 1.4e-05 23.9 19.5 1.4e-05 23.9 19.5 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein Aldo_ket_red PF00248.21 KXL44114.1 - 3.8e-49 167.5 0.0 6.1e-49 166.8 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family IlvN PF07991.12 KXL44114.1 - 0.11 12.1 0.4 1.1 8.8 0.4 2.1 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Beta-lactamase PF00144.24 KXL44115.1 - 1.4e-28 100.1 0.0 2.3e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase Fe_hyd_lg_C PF02906.14 KXL44116.1 - 5.1e-57 193.3 0.0 1e-56 192.4 0.0 1.5 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain DNA_RNApol_7kD PF03604.13 KXL44117.1 - 1.9e-17 62.6 6.5 2.6e-17 62.2 6.5 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.19 KXL44117.1 - 0.00024 21.1 0.0 0.00029 20.8 0.0 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KXL44117.1 - 0.0089 16.0 0.3 0.012 15.6 0.3 1.2 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_13 PF09855.9 KXL44117.1 - 0.019 15.1 0.1 0.038 14.2 0.1 1.5 1 0 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) DUF2197 PF09963.9 KXL44117.1 - 0.023 14.9 2.2 0.57 10.5 0.2 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) Zn-ribbon_8 PF09723.10 KXL44117.1 - 0.026 14.6 0.7 0.047 13.8 0.7 1.4 1 0 0 1 1 1 0 Zinc ribbon domain DUF2757 PF10955.8 KXL44117.1 - 0.094 13.0 0.2 0.12 12.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) zf_UBZ PF18439.1 KXL44117.1 - 0.29 10.8 0.7 12 5.6 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger LYRIC PF15686.5 KXL44118.1 - 0.078 12.5 6.3 0.1 12.1 6.3 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family AP3D1 PF06375.11 KXL44118.1 - 0.35 11.1 5.2 0.48 10.7 5.2 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Pkinase PF00069.25 KXL44119.1 - 2.1e-58 197.8 2.0 2.1e-57 194.5 0.0 2.6 2 1 0 2 2 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL44119.1 - 5.3e-25 88.2 0.2 6.7e-20 71.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KXL44119.1 - 3.1e-06 26.4 0.3 7.2e-06 25.2 0.2 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KXL44119.1 - 0.00057 19.3 1.1 0.0034 16.8 0.0 2.5 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXL44119.1 - 0.0033 17.4 7.4 0.038 13.9 0.1 2.6 2 1 1 3 3 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KXL44119.1 - 0.0052 16.1 1.2 0.021 14.2 0.0 2.3 2 0 0 2 2 2 1 Kinase-like DUF2722 PF10846.8 KXL44119.1 - 0.0052 15.8 8.0 0.0092 15.0 8.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Pox_ser-thr_kin PF05445.11 KXL44119.1 - 0.11 11.4 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 KXL44119.1 - 0.11 12.1 0.0 0.11 12.1 0.0 2.2 3 0 0 3 3 3 0 RIO1 family Spt20 PF12090.8 KXL44119.1 - 0.63 9.6 19.3 1.7 8.2 19.3 1.8 1 0 0 1 1 1 0 Spt20 family EPL1 PF10513.9 KXL44119.1 - 5.3 7.4 8.4 0.45 10.9 2.2 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like Pkinase PF00069.25 KXL44120.1 - 1.2e-18 67.4 0.0 1.5e-18 67.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL44120.1 - 4.5e-17 62.2 0.0 5.4e-17 61.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXL44120.1 - 8.2e-05 22.6 0.2 0.13 12.1 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KXL44120.1 - 0.02 14.3 0.0 0.027 13.8 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BAR_3 PF16746.5 KXL44121.1 - 9.9e-14 51.6 0.0 1.7e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 BAR domain of APPL family VASt PF16016.5 KXL44121.1 - 4.6e-08 33.6 0.0 1.7e-05 25.3 0.0 2.3 1 1 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain PH PF00169.29 KXL44121.1 - 2.4e-07 31.2 0.0 5.4e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 PH domain GRAM PF02893.20 KXL44121.1 - 0.047 13.6 0.0 0.097 12.6 0.0 1.4 1 0 0 1 1 1 0 GRAM domain Ank_2 PF12796.7 KXL44122.1 - 1.3e-20 73.7 7.7 9.7e-12 45.3 1.2 3.0 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXL44122.1 - 7.4e-17 61.5 4.8 4.5e-08 33.5 0.1 4.4 2 1 2 4 4 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KXL44122.1 - 3.3e-16 58.9 9.0 0.0028 18.1 0.1 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KXL44122.1 - 8.9e-13 47.2 1.3 0.29 11.8 0.0 5.0 4 0 0 4 4 4 4 Ankyrin repeat HET PF06985.11 KXL44122.1 - 2.5e-10 40.9 7.5 3.3e-08 34.0 1.1 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) NACHT PF05729.12 KXL44122.1 - 6.9e-09 35.8 0.0 1.6e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Ank_5 PF13857.6 KXL44122.1 - 3.9e-08 33.4 4.1 0.011 16.0 0.3 4.6 2 1 3 5 5 4 4 Ankyrin repeats (many copies) AAA_16 PF13191.6 KXL44122.1 - 0.00036 21.0 0.1 0.0024 18.3 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 KXL44122.1 - 0.0032 17.8 0.0 0.013 15.9 0.0 2.1 1 0 0 1 1 1 1 RNA helicase ATPase_2 PF01637.18 KXL44122.1 - 0.0058 16.6 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KXL44122.1 - 0.027 14.2 0.2 0.63 9.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KXL44122.1 - 0.08 13.2 0.1 0.34 11.2 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 KXL44122.1 - 0.08 13.0 0.0 0.43 10.6 0.0 2.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KXL44122.1 - 0.081 13.3 0.0 0.28 11.6 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HTH_IclR PF09339.10 KXL44122.1 - 0.45 10.4 2.0 0.81 9.5 0.2 2.5 2 0 0 2 2 2 0 IclR helix-turn-helix domain DUF5102 PF17104.5 KXL44123.1 - 0.12 12.4 15.1 0.21 11.6 0.8 3.2 2 2 1 3 3 3 0 Domain of unknown function (DUF5102) PhoLip_ATPase_C PF16212.5 KXL44124.1 - 1e-68 231.8 13.6 1e-68 231.8 13.6 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KXL44124.1 - 3.1e-20 71.6 2.3 2.8e-19 68.6 0.1 2.5 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KXL44124.1 - 1.4e-12 48.3 0.1 9.9e-05 22.7 0.0 3.4 2 1 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXL44124.1 - 9.1e-12 44.9 0.0 1.3e-10 41.2 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KXL44124.1 - 1.2e-10 41.2 0.0 3.3e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KXL44124.1 - 0.0032 17.3 0.0 0.01 15.6 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3602 PF12223.8 KXL44125.1 - 1.5e-08 35.1 9.3 0.00023 21.7 2.6 3.3 2 2 1 3 3 3 3 Protein of unknown function (DUF3602) Ribosomal_L24e PF01246.20 KXL44127.1 - 4.3e-32 110.1 6.6 4.3e-32 110.1 6.6 2.5 3 0 0 3 3 3 1 Ribosomal protein L24e PGA2 PF07543.12 KXL44127.1 - 0.14 12.1 8.9 0.25 11.3 8.9 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 Abhydrolase_6 PF12697.7 KXL44128.1 - 2e-08 35.1 0.1 2.9e-08 34.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Methyltransf_31 PF13847.6 KXL44129.1 - 1.1e-17 64.3 0.0 1.5e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL44129.1 - 1.4e-07 32.1 0.0 2.7e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL44129.1 - 3.6e-07 30.8 0.0 6.9e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KXL44129.1 - 5.3e-05 23.3 0.0 8.1e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXL44129.1 - 0.00015 21.7 0.0 0.00022 21.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL44129.1 - 0.00061 20.4 0.0 0.0011 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXL44129.1 - 0.058 12.9 0.0 0.085 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain AdoMet_MTase PF07757.13 KXL44129.1 - 0.093 13.1 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase MetW PF07021.12 KXL44129.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Mannosyl_trans3 PF11051.8 KXL44130.1 - 6.7e-50 170.0 0.0 2.9e-47 161.3 0.0 2.1 1 1 0 1 1 1 1 Mannosyltransferase putative YadA_anchor PF03895.15 KXL44130.1 - 0.12 12.5 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 YadA-like membrane anchor domain CoA_transf_3 PF02515.17 KXL44132.1 - 5.2e-41 141.0 0.1 1.3e-37 129.8 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III Glyoxalase_3 PF13468.6 KXL44133.1 - 6.9e-28 97.9 0.0 9.3e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain EamA PF00892.20 KXL44134.1 - 4.1e-10 40.0 24.4 9e-05 22.7 11.7 2.5 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KXL44134.1 - 1.1e-09 37.9 0.9 2e-09 37.1 0.9 1.4 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 KXL44134.1 - 3.6e-08 33.0 0.0 7.1e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 KXL44134.1 - 0.00032 20.1 0.3 0.00032 20.1 0.3 2.0 3 0 0 3 3 3 1 Triose-phosphate Transporter family CRT-like PF08627.10 KXL44134.1 - 8.1 5.3 9.2 3.4 6.5 0.0 3.0 4 0 0 4 4 4 0 CRT-like, chloroquine-resistance transporter-like MBOAT PF03062.19 KXL44136.1 - 8.5e-43 147.0 15.0 2.1e-41 142.4 9.7 2.1 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family FAD_binding_3 PF01494.19 KXL44137.1 - 6.1e-15 55.3 11.1 1.2e-11 44.5 0.1 2.9 2 1 0 2 2 2 2 FAD binding domain SE PF08491.10 KXL44137.1 - 4e-07 29.4 0.0 8.7e-05 21.7 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase Amino_oxidase PF01593.24 KXL44137.1 - 0.013 14.8 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KXL44137.1 - 0.015 15.3 0.5 0.52 10.3 0.2 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.24 KXL44137.1 - 0.035 13.7 3.4 0.48 9.9 0.4 2.4 2 1 0 2 2 2 0 FAD dependent oxidoreductase Cullin_binding PF03556.15 KXL44138.1 - 5.7e-31 107.5 1.3 7.4e-31 107.1 1.3 1.1 1 0 0 1 1 1 1 Cullin binding Arylsulfotran_2 PF14269.6 KXL44140.1 - 1.1e-81 274.5 0.0 1.3e-81 274.3 0.0 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXL44140.1 - 3.4e-16 59.1 0.0 7.9e-15 54.6 0.0 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) FNIP PF05725.12 KXL44140.1 - 0.13 12.5 0.0 0.39 10.9 0.0 1.8 1 0 0 1 1 1 0 FNIP Repeat DUF2263 PF10021.9 KXL44141.1 - 1.8e-18 67.3 0.0 5.9e-18 65.7 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.21 KXL44141.1 - 0.0019 18.3 0.0 0.0039 17.2 0.0 1.5 1 0 0 1 1 1 1 Macro domain DUF2883 PF11097.8 KXL44142.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2883) Cactin_mid PF10312.9 KXL44145.1 - 0.033 13.9 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Conserved mid region of cactin zf-RING_2 PF13639.6 KXL44146.1 - 0.48 10.8 15.9 1.4 9.3 15.9 1.9 1 1 0 1 1 1 0 Ring finger domain zf-C2H2 PF00096.26 KXL44147.1 - 1.6e-18 66.0 24.9 0.00021 21.6 0.5 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXL44147.1 - 7.3e-17 60.9 22.7 2.2e-08 34.2 1.1 4.9 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXL44147.1 - 1.7e-08 34.5 22.3 0.021 15.7 0.9 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KXL44147.1 - 3.3e-05 24.1 6.8 0.017 15.4 1.3 3.1 1 1 2 3 3 3 3 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 KXL44147.1 - 0.00028 21.1 8.9 0.17 12.0 0.3 3.6 2 2 2 4 4 4 2 Aberrant zinc-finger zf-met PF12874.7 KXL44147.1 - 0.00033 20.9 11.7 0.18 12.2 0.4 4.4 4 0 0 4 4 4 2 Zinc-finger of C2H2 type RteC PF09357.10 KXL44147.1 - 0.046 13.4 0.1 0.08 12.6 0.1 1.3 1 0 0 1 1 1 0 RteC protein zf-DNA_Pol PF08996.10 KXL44147.1 - 0.13 12.0 5.8 0.78 9.5 1.1 2.2 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger zf_UBZ PF18439.1 KXL44147.1 - 0.81 9.3 4.8 2.8 7.6 0.1 3.5 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger FOXP-CC PF16159.5 KXL44147.1 - 0.86 10.3 4.5 11 6.7 0.1 2.9 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KXL44147.1 - 1.3 9.2 21.3 0.33 11.0 0.7 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger FYVE PF01363.21 KXL44147.1 - 2.6 8.2 11.7 1 9.5 4.6 2.8 1 1 1 2 2 2 0 FYVE zinc finger zf-LYAR PF08790.11 KXL44147.1 - 3.7 7.5 12.5 27 4.8 0.5 4.3 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger Stk19 PF10494.9 KXL44149.1 - 1.6e-76 257.2 0.0 2.1e-76 256.9 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 DAGAT PF03982.13 KXL44150.1 - 6.7e-92 307.6 0.0 7.9e-92 307.3 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.13 KXL44150.1 - 0.1 12.4 0.4 0.17 11.6 0.4 1.2 1 0 0 1 1 1 0 Rer1 family Baculo_PEP_C PF04513.12 KXL44151.1 - 0.021 14.9 2.8 0.042 13.9 1.7 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Myosin_N PF02736.19 KXL44151.1 - 0.69 9.8 4.9 11 6.0 0.1 3.5 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain Pex2_Pex12 PF04757.14 KXL44152.1 - 6.8e-44 150.1 7.4 9.7e-44 149.6 7.4 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 KXL44152.1 - 9.5e-12 44.6 10.8 1.7e-11 43.8 10.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXL44152.1 - 5.6e-11 42.6 10.1 9.5e-11 41.9 10.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KXL44152.1 - 1.9e-10 40.5 6.8 3e-10 39.8 6.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXL44152.1 - 1.9e-09 37.3 7.6 3.1e-09 36.6 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXL44152.1 - 5.6e-08 32.7 8.7 1.1e-07 31.7 8.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXL44152.1 - 2.3e-07 30.7 6.7 4e-07 29.9 6.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KXL44152.1 - 6.2e-07 29.2 8.0 1e-06 28.5 8.0 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KXL44152.1 - 1.8e-06 28.0 8.7 3e-06 27.3 8.7 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KXL44152.1 - 4.9e-06 26.7 11.1 5.7e-06 26.5 9.9 1.8 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 KXL44152.1 - 2.5e-05 24.1 2.5 4.7e-05 23.2 2.5 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Nse PF11789.8 KXL44152.1 - 0.03 14.1 2.7 0.061 13.1 2.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 KXL44152.1 - 0.039 14.1 7.8 0.067 13.3 7.8 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KXL44152.1 - 0.067 13.0 7.2 0.15 11.8 7.2 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KXL44152.1 - 0.095 12.8 8.9 0.15 12.1 6.5 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KXL44152.1 - 0.49 10.1 6.4 0.89 9.2 6.4 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KXL44152.1 - 0.52 10.1 2.7 1.1 9.1 2.7 1.6 1 0 0 1 1 1 0 RING-like zinc finger DZR PF12773.7 KXL44152.1 - 0.82 9.8 5.5 1.6 8.9 5.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon IBR PF01485.21 KXL44152.1 - 0.99 9.7 5.5 2.4 8.5 5.5 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain ArfGap PF01412.18 KXL44153.1 - 3.1e-35 120.8 0.0 3.1e-35 120.8 0.0 2.9 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 KXL44153.1 - 9.4e-17 61.5 14.7 1.8e-16 60.6 14.7 1.3 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 KXL44153.1 - 2.7e-13 50.3 1.0 6.5e-13 49.1 0.1 2.2 2 0 0 2 2 2 1 PH domain GyrB_insert PF18053.1 KXL44153.1 - 0.8 9.6 4.0 3.5 7.5 0.2 2.7 3 0 0 3 3 3 0 DNA gyrase B subunit insert domain 4HBT_3 PF13622.6 KXL44154.1 - 1.3e-49 169.7 0.0 1.5e-49 169.5 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 KXL44154.1 - 0.017 15.5 0.4 0.031 14.6 0.4 1.4 1 0 0 1 1 1 0 Thioesterase superfamily ERAP1_C PF11838.8 KXL44155.1 - 1.3e-87 294.3 2.2 4.6e-87 292.5 0.4 2.4 2 1 1 3 3 3 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KXL44155.1 - 6.5e-85 284.1 0.4 1.3e-84 283.1 0.4 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KXL44155.1 - 1.1e-52 179.0 2.5 3.4e-52 177.3 1.3 2.1 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 KXL44155.1 - 9.1e-05 22.5 0.0 0.0002 21.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2808) Melibiase_2 PF16499.5 KXL44157.1 - 2.5e-17 63.0 1.4 3.7e-17 62.4 1.4 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KXL44157.1 - 1e-10 41.6 0.1 1.7e-10 40.8 0.1 1.4 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain DUF3543 PF12063.8 KXL44158.1 - 7.2e-83 277.8 0.1 1.2e-82 277.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 KXL44158.1 - 1.1e-60 205.3 0.0 1.9e-60 204.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL44158.1 - 1.5e-40 139.1 0.0 2.6e-40 138.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXL44158.1 - 0.0041 17.1 0.1 0.083 12.8 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXL44158.1 - 0.017 13.9 0.2 0.069 11.9 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase NAD_Gly3P_dh_N PF01210.23 KXL44159.1 - 1e-45 155.5 0.0 4.1e-45 153.6 0.0 1.9 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 KXL44159.1 - 1e-43 149.1 0.1 2e-43 148.1 0.1 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 KXL44159.1 - 0.012 16.1 0.0 7.4 7.2 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent MFS_1 PF07690.16 KXL44161.1 - 4.7e-32 111.3 27.9 4.7e-32 111.3 27.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Gly-zipper_Omp PF13488.6 KXL44161.1 - 0.25 11.4 2.7 0.26 11.3 0.2 2.3 2 0 0 2 2 2 0 Glycine zipper Methyltransf_25 PF13649.6 KXL44163.1 - 0.00023 21.8 0.0 0.0007 20.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain DUF1365 PF07103.11 KXL44164.1 - 1.1e-63 215.1 0.2 2.3e-63 214.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1365) DUF1601 PF07671.11 KXL44164.1 - 0.036 13.9 0.2 0.26 11.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1601) Nop53 PF07767.11 KXL44165.1 - 5.7 6.2 14.2 0.23 10.8 7.8 1.8 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Tfb4 PF03850.14 KXL44166.1 - 5.8 6.3 6.8 7.9 5.9 6.8 1.1 1 0 0 1 1 1 0 Transcription factor Tfb4 MFS_1 PF07690.16 KXL44167.1 - 6.1e-35 120.8 41.3 6.1e-35 120.8 41.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_transport PF06800.12 KXL44167.1 - 0.0014 18.0 0.3 0.0014 18.0 0.3 2.2 3 0 0 3 3 3 1 Sugar transport protein SUR7 PF06687.12 KXL44167.1 - 0.014 15.0 2.1 0.014 15.0 2.1 3.0 3 1 0 3 3 3 0 SUR7/PalI family RRN3 PF05327.11 KXL44168.1 - 2.1 6.8 3.6 2.5 6.5 3.6 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 eIF-5_eIF-2B PF01873.17 KXL44169.1 - 1.8e-41 140.7 0.1 3.1e-41 139.9 0.1 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 zf-HYPF PF07503.12 KXL44169.1 - 0.23 11.2 2.3 13 5.7 0.0 2.8 3 0 0 3 3 3 0 HypF finger Arc_trans_TRASH PF08394.10 KXL44169.1 - 1.8 9.0 7.3 1.2 9.6 0.3 2.5 1 1 1 2 2 2 0 Archaeal TRASH domain Ino80_Iec3 PF14612.6 KXL44170.1 - 3.1e-49 168.8 0.0 4e-49 168.4 0.0 1.1 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling HALZ PF02183.18 KXL44170.1 - 0.026 14.7 0.1 0.057 13.6 0.1 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper RRM_1 PF00076.22 KXL44171.1 - 1.8e-20 72.5 0.0 8.6e-12 44.7 0.0 3.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXL44171.1 - 0.0022 18.1 0.0 0.1 12.7 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif RRM_Rrp7 PF17799.1 KXL44171.1 - 0.092 12.5 0.0 17 5.2 0.0 2.3 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain CPSF100_C PF13299.6 KXL44171.1 - 0.13 12.4 2.8 0.33 11.1 0.7 2.3 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Dicty_REP PF05086.12 KXL44171.1 - 0.19 9.7 5.9 0.25 9.3 5.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein adh_short PF00106.25 KXL44173.1 - 3.1e-32 111.6 0.3 4.1e-32 111.2 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL44173.1 - 1.6e-27 96.5 0.0 2.1e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL44173.1 - 4.3e-11 43.1 0.3 6.4e-11 42.5 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL44173.1 - 0.0012 18.4 0.2 0.69 9.3 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family LPD28 PF18843.1 KXL44173.1 - 0.08 12.6 0.0 0.37 10.4 0.0 2.0 2 1 0 2 2 2 0 Large polyvalent protein associated domain 28 SpoU_methylase PF00588.19 KXL44174.1 - 2.4e-23 82.9 0.0 6e-23 81.6 0.0 1.7 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KXL44174.1 - 1.1e-12 48.1 0.0 2e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding zf-PHD-like PF15446.6 KXL44175.1 - 2.2e-64 216.1 14.8 2.2e-64 216.1 14.8 2.1 2 0 0 2 2 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.23 KXL44175.1 - 7.6e-52 176.2 0.0 1.3e-51 175.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-CCCH_6 PF18585.1 KXL44175.1 - 5.3e-26 90.3 0.5 1.5e-25 88.8 0.5 1.9 1 0 0 1 1 1 1 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Helicase_C PF00271.31 KXL44175.1 - 2e-19 69.9 0.0 6.2e-19 68.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL44175.1 - 6.2e-07 29.6 0.4 5.6e-05 23.2 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Chromo PF00385.24 KXL44175.1 - 8.4e-07 28.8 0.1 0.68 9.9 0.2 4.0 3 0 0 3 3 3 3 Chromo (CHRromatin Organisation MOdifier) domain HDA2-3 PF11496.8 KXL44175.1 - 1.5e-05 24.3 0.1 1.5e-05 24.3 0.1 2.5 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 PHD PF00628.29 KXL44175.1 - 0.00039 20.3 4.7 0.00039 20.3 4.7 3.9 4 1 0 4 4 3 1 PHD-finger Myc_N PF01056.18 KXL44175.1 - 0.0063 16.5 12.2 0.022 14.6 12.2 1.9 1 0 0 1 1 1 1 Myc amino-terminal region Paf1 PF03985.13 KXL44175.1 - 0.28 10.1 21.8 0.62 9.0 21.8 1.5 1 0 0 1 1 1 0 Paf1 MCM_bind PF09739.9 KXL44175.1 - 1.5 7.2 9.5 2.8 6.3 9.5 1.3 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor PHD_2 PF13831.6 KXL44175.1 - 6.9 6.3 13.4 1.1 8.9 5.8 3.2 2 1 0 2 2 2 0 PHD-finger CPSF100_C PF13299.6 KXL44175.1 - 9.3 6.4 12.3 35 4.5 12.3 2.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal PLDc PF00614.22 KXL44176.1 - 4.3e-15 55.2 0.3 1e-06 28.7 0.2 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KXL44176.1 - 2.9e-14 53.1 0.0 4.3e-08 33.1 0.0 3.0 3 0 0 3 3 3 2 PLD-like domain PX PF00787.24 KXL44176.1 - 9.1e-10 38.5 1.0 3.3e-09 36.7 0.1 2.5 3 0 0 3 3 3 1 PX domain IQCJ-SCHIP1 PF15157.6 KXL44176.1 - 0.035 14.0 0.1 0.078 12.8 0.1 1.5 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Phage_head_chap PF11113.8 KXL44176.1 - 0.084 13.0 0.0 0.87 9.7 0.0 2.6 2 0 0 2 2 2 0 Head assembly gene product Trimer_CC PF08954.11 KXL44176.1 - 0.24 11.0 2.2 1.2 8.7 0.2 2.7 2 0 0 2 2 2 0 Trimerisation motif GST_N_3 PF13417.6 KXL44177.1 - 4.7e-05 23.7 0.0 0.00017 22.0 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXL44177.1 - 6.9e-05 23.1 0.0 0.00013 22.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXL44177.1 - 0.00084 19.3 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXL44177.1 - 0.00085 19.5 0.0 0.0014 18.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXL44177.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Asp_protease_2 PF13650.6 KXL44178.1 - 0.0017 19.0 0.0 0.0031 18.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KXL44178.1 - 0.005 17.4 0.1 0.024 15.2 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 KXL44178.1 - 0.043 13.6 0.0 0.11 12.3 0.0 1.6 2 0 0 2 2 2 0 Retroviral aspartyl protease DUF1961 PF09224.11 KXL44178.1 - 0.18 11.2 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1961) zf-CCHC_5 PF14787.6 KXL44178.1 - 0.23 11.2 2.5 0.7 9.7 1.1 2.2 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 KXL44178.1 - 0.24 11.5 1.0 0.4 10.8 1.0 1.4 1 0 0 1 1 1 0 Zinc knuckle Cwf_Cwc_15 PF04889.12 KXL44178.1 - 2.4 7.8 11.9 0.37 10.5 7.9 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Tash_PEST PF07708.11 KXL44179.1 - 0.13 12.4 0.9 0.3 11.3 0.9 1.6 1 0 0 1 1 1 0 Tash protein PEST motif Peptidase_C14 PF00656.22 KXL44180.1 - 4.2e-40 138.3 0.0 6.2e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Mpv17_PMP22 PF04117.12 KXL44181.1 - 4.2e-16 58.9 3.1 9e-16 57.9 3.1 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family Histone PF00125.24 KXL44182.1 - 4e-52 176.0 2.5 4.5e-52 175.9 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KXL44182.1 - 6e-06 26.6 0.0 9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 KXL44182.1 - 4e-05 24.2 1.2 4.7e-05 24.0 1.2 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 KXL44182.1 - 4.3e-05 23.6 0.4 7.4e-05 22.8 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KXL44182.1 - 0.0038 17.5 0.4 0.0065 16.7 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KXL44182.1 - 0.026 14.6 0.2 0.042 13.9 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 KXL44183.1 - 7.8e-09 35.6 0.1 9.4e-09 35.4 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KXL44183.1 - 2.3e-05 24.8 0.1 2.7e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KXL44183.1 - 7e-05 22.9 0.1 0.0001 22.4 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXL44183.1 - 0.00019 21.6 0.1 0.00034 20.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KXL44183.1 - 0.00039 20.7 0.1 0.00055 20.3 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KXL44183.1 - 0.0082 16.2 0.0 0.0098 16.0 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXL44183.1 - 0.031 14.3 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KXL44183.1 - 0.051 13.4 0.2 0.062 13.1 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 KXL44183.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region HAD_2 PF13419.6 KXL44184.1 - 5.5e-08 33.1 0.0 5.9e-08 33.0 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXL44184.1 - 1.9e-06 28.3 0.0 5.9e-06 26.7 0.0 1.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXL44184.1 - 0.00024 21.1 0.0 0.00056 19.9 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like MFS_1 PF07690.16 KXL44185.1 - 3.4e-44 151.2 22.2 3.4e-44 151.2 22.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL44185.1 - 3.7e-09 36.0 8.7 3.7e-09 36.0 8.7 2.6 2 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KXL44185.1 - 7.6e-06 24.6 4.5 1.3e-05 23.9 4.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KXL44185.1 - 0.00064 18.2 0.5 0.0013 17.3 0.5 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector Phage_holin_2_4 PF16082.5 KXL44185.1 - 2.7 7.8 0.0 2.7 7.8 0.0 3.4 3 1 0 3 3 3 0 Bacteriophage holin family, superfamily II-like RRM_1 PF00076.22 KXL44187.1 - 1.4e-11 44.0 0.0 2e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXL44187.1 - 0.00019 21.3 0.0 0.00027 20.9 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DNA_pol_phi PF04931.13 KXL44188.1 - 7.8e-159 530.2 10.1 9.6e-159 529.9 10.1 1.1 1 0 0 1 1 1 1 DNA polymerase phi DUF3653 PF12375.8 KXL44188.1 - 0.0055 16.8 0.0 0.067 13.3 0.0 2.5 2 0 0 2 2 2 1 Phage protein Drc1-Sld2 PF11719.8 KXL44188.1 - 3 7.3 7.1 6 6.3 7.1 1.4 1 0 0 1 1 1 0 DNA replication and checkpoint protein SDA1 PF05285.12 KXL44188.1 - 6.2 6.1 15.8 11 5.3 15.8 1.3 1 0 0 1 1 1 0 SDA1 Pyrid_ox_like PF16242.5 KXL44189.1 - 1.3e-26 92.9 0.0 1.9e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 KXL44189.1 - 4.3e-07 30.0 0.0 7.9e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase EMP70 PF02990.16 KXL44190.1 - 8.9e-204 677.9 3.1 8.9e-204 677.9 3.1 1.3 2 0 0 2 2 2 1 Endomembrane protein 70 MOZ_SAS PF01853.18 KXL44191.1 - 1.4e-65 220.3 0.0 1.8e-65 220.0 0.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KXL44191.1 - 1.8e-16 59.5 1.5 3.6e-16 58.5 1.5 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 KXL44191.1 - 0.021 15.2 0.0 0.043 14.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4258 PF14076.6 KXL44191.1 - 0.09 13.2 0.1 0.19 12.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4258) Acetyltransf_1 PF00583.25 KXL44191.1 - 0.1 12.9 0.0 0.21 11.8 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Clat_adaptor_s PF01217.20 KXL44192.1 - 3.7e-14 52.9 1.4 4.8e-13 49.3 1.4 2.0 1 1 0 1 1 1 1 Clathrin adaptor complex small chain DUF4804 PF16062.5 KXL44192.1 - 0.14 10.9 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4804) PPR_3 PF13812.6 KXL44193.1 - 0.0036 17.4 0.2 5.5 7.1 0.0 3.5 2 1 0 3 3 3 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 KXL44193.1 - 0.049 13.8 0.0 0.5 10.6 0.0 2.6 3 0 0 3 3 3 0 PPR repeat family RsgA_N PF16745.5 KXL44194.1 - 0.15 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 RsgA N-terminal domain DUF3445 PF11927.8 KXL44195.1 - 2.6e-77 259.5 0.0 3.3e-77 259.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Glyco_transf_22 PF03901.17 KXL44196.1 - 7.1e-83 279.2 24.6 8.2e-83 278.9 24.6 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Gar1 PF04410.14 KXL44197.1 - 3.2e-21 75.7 0.4 4.3e-21 75.3 0.4 1.2 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Exo5 PF09810.9 KXL44198.1 - 5.4e-130 434.1 0.0 7e-130 433.8 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease DUF5076 PF16826.5 KXL44198.1 - 0.068 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5076) TFIIIC_sub6 PF10419.9 KXL44199.1 - 2.3e-14 53.0 0.0 3.4e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain Vps62 PF06101.11 KXL44201.1 - 3.3e-07 29.0 0.1 0.00058 18.3 0.1 2.3 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 62 ABC_tran PF00005.27 KXL44203.1 - 1.1e-31 110.2 0.0 1.6e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KXL44203.1 - 9.7e-07 28.4 0.4 0.00015 21.3 0.4 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DEAD PF00270.29 KXL44203.1 - 0.00049 19.9 0.0 0.14 11.9 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_21 PF13304.6 KXL44203.1 - 0.0013 18.6 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 KXL44203.1 - 0.0021 18.2 0.4 0.006 16.7 0.1 1.7 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 KXL44203.1 - 0.0032 17.7 0.9 0.089 13.1 0.9 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXL44203.1 - 0.0048 17.3 0.5 0.0093 16.4 0.5 1.7 1 1 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 KXL44203.1 - 0.018 14.1 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.29 KXL44203.1 - 0.022 15.2 0.2 0.23 11.9 0.2 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 KXL44203.1 - 0.023 14.7 0.1 0.13 12.2 0.0 2.2 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 KXL44203.1 - 0.033 13.9 0.0 0.089 12.5 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein CbiA PF01656.23 KXL44203.1 - 0.033 14.2 0.0 0.056 13.5 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain TrwB_AAD_bind PF10412.9 KXL44203.1 - 0.036 13.0 0.0 0.061 12.2 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 KXL44203.1 - 0.043 13.5 0.1 0.74 9.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 KXL44203.1 - 0.044 13.2 0.0 0.084 12.3 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_29 PF13555.6 KXL44203.1 - 0.053 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KXL44203.1 - 0.053 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 KXL44203.1 - 0.072 13.2 0.1 0.19 11.8 0.0 1.8 2 0 0 2 2 1 0 50S ribosome-binding GTPase NACHT PF05729.12 KXL44203.1 - 0.073 13.0 0.3 0.52 10.2 0.0 2.2 2 1 1 3 3 3 0 NACHT domain AAA_25 PF13481.6 KXL44203.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KXL44203.1 - 0.14 11.6 0.0 0.32 10.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Macoilin PF09726.9 KXL44205.1 - 1 7.9 6.7 1.5 7.3 6.7 1.2 1 0 0 1 1 1 0 Macoilin family DUF2197 PF09963.9 KXL44205.1 - 2 8.7 4.6 4.5 7.6 4.6 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) ECH_1 PF00378.20 KXL44206.1 - 7e-38 130.4 0.1 8.4e-38 130.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXL44206.1 - 5.7e-22 78.7 0.1 9.5e-22 77.9 0.1 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Isochorismatase PF00857.20 KXL44207.1 - 6e-16 59.1 0.0 2.6e-15 57.0 0.0 1.9 1 1 0 1 1 1 1 Isochorismatase family zf-C2H2 PF00096.26 KXL44208.1 - 0.00029 21.1 3.8 0.00029 21.1 3.8 2.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXL44208.1 - 0.0015 19.2 2.9 0.0015 19.2 2.9 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXL44208.1 - 0.0024 17.8 0.4 0.005 16.8 0.4 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXL44208.1 - 0.0053 17.0 0.9 0.017 15.4 0.9 2.0 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KXL44208.1 - 0.017 15.6 0.2 0.017 15.6 0.2 3.7 3 0 0 3 3 3 0 Zinc-finger double domain zf-H2C2_5 PF13909.6 KXL44208.1 - 0.028 14.2 12.0 0.029 14.1 0.4 3.4 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Zn-C2H2_12 PF18112.1 KXL44208.1 - 0.59 10.6 3.7 1.9 9.1 3.7 1.9 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain HECT_2 PF09814.9 KXL44210.1 - 6.4e-79 265.5 0.0 7.3e-79 265.3 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Zn_ribbon_recom PF13408.6 KXL44210.1 - 0.013 16.0 5.2 0.15 12.6 0.4 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zinc_ribbon_2 PF13240.6 KXL44210.1 - 0.059 13.1 0.8 0.31 10.8 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Acetyltransf_1 PF00583.25 KXL44211.1 - 2.2e-07 31.1 0.0 2.9e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXL44211.1 - 1.6e-05 24.8 0.0 2.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXL44211.1 - 1.9e-05 25.0 0.0 3.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXL44211.1 - 0.0066 16.4 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KXL44211.1 - 0.022 14.8 0.0 0.29 11.2 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain 3Beta_HSD PF01073.19 KXL44212.1 - 3.4e-51 173.9 0.0 4.3e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXL44212.1 - 3.5e-24 85.6 0.0 4.7e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXL44212.1 - 3.9e-14 52.8 0.1 4.2e-11 42.8 0.2 2.5 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KXL44212.1 - 7.5e-12 45.0 0.0 2.8e-08 33.3 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 KXL44212.1 - 3.3e-11 42.8 0.0 5.3e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KXL44212.1 - 3.2e-08 33.0 0.5 2.9e-07 29.9 0.5 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KXL44212.1 - 4.7e-06 26.6 0.0 7.3e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KXL44212.1 - 0.00017 21.6 0.5 0.0044 17.0 0.5 2.5 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 KXL44212.1 - 0.023 14.2 0.3 0.15 11.6 0.3 2.0 1 1 0 1 1 1 0 NmrA-like family DUF2552 PF10827.8 KXL44212.1 - 0.18 12.0 0.1 0.53 10.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2552) Pkinase PF00069.25 KXL44213.1 - 2e-62 211.0 0.0 4.1e-62 209.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL44213.1 - 5e-34 117.8 0.0 1.2e-33 116.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KXL44213.1 - 4.1e-09 36.7 0.1 3.9e-08 33.5 0.0 2.4 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KXL44213.1 - 3e-05 24.3 0.0 7.8e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 KXL44213.1 - 0.00026 20.4 0.0 0.00046 19.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXL44213.1 - 0.00089 18.6 0.0 0.005 16.2 0.0 2.0 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXL44213.1 - 0.0054 15.6 0.0 0.0084 14.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 KXL44213.1 - 0.14 11.6 0.0 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL FMO-like PF00743.19 KXL44214.1 - 3.8e-13 48.7 0.2 1.7e-12 46.6 0.0 2.0 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXL44214.1 - 9.6e-13 48.0 0.0 2.4e-12 46.7 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXL44214.1 - 8.5e-12 44.9 0.0 1.3e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXL44214.1 - 1.8e-10 40.9 0.0 1.3e-07 31.7 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXL44214.1 - 2e-07 30.5 0.0 1.9e-06 27.3 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 KXL44214.1 - 4.4e-06 26.0 0.1 0.019 14.0 0.0 2.9 2 1 0 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.6 KXL44214.1 - 2.3e-05 24.4 1.7 0.0074 16.3 0.2 3.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KXL44214.1 - 0.00011 22.7 0.5 0.075 13.6 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXL44214.1 - 0.0025 17.1 0.0 0.2 10.8 0.0 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 KXL44214.1 - 0.0082 15.3 1.0 0.05 12.7 0.0 2.3 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 KXL44214.1 - 0.028 13.1 1.0 1.1 7.8 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.24 KXL44214.1 - 0.029 14.0 3.8 0.078 12.5 0.3 2.5 2 1 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KXL44214.1 - 0.047 14.1 0.0 2.1 8.8 0.0 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KXL44214.1 - 0.095 11.9 1.1 0.34 10.1 0.0 2.3 3 0 0 3 3 3 0 FAD binding domain 3HCDH_N PF02737.18 KXL44214.1 - 0.12 12.2 0.1 2.6 7.9 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KXL44214.1 - 0.14 11.5 0.0 0.58 9.5 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KXL44214.1 - 0.15 11.7 0.4 11 5.7 0.2 2.4 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DRMBL PF07522.14 KXL44215.1 - 1.4e-33 115.3 0.0 2.7e-33 114.4 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 KXL44215.1 - 3.6e-05 23.4 0.0 6.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TPP_enzyme_N PF02776.18 KXL44216.1 - 1.5e-39 135.4 1.9 1.5e-39 135.4 1.9 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KXL44216.1 - 2.2e-34 118.4 0.8 6.9e-34 116.8 0.1 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXL44216.1 - 6.6e-23 81.0 0.0 1.4e-22 79.9 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Glyoxalase_6 PF18029.1 KXL44216.1 - 0.012 16.4 0.2 0.067 14.0 0.0 2.4 2 1 0 2 2 2 0 Glyoxalase-like domain POR_N PF01855.19 KXL44216.1 - 0.069 12.9 1.9 0.11 12.2 1.9 1.3 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg UPF0029 PF01205.19 KXL44217.1 - 1.4e-16 60.7 0.0 2.3e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Nbl1_Borealin_N PF10444.9 KXL44218.1 - 1.5e-18 66.2 6.5 2.3e-18 65.6 6.5 1.3 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal DAP_epimerase PF01678.19 KXL44218.1 - 0.018 15.2 1.5 0.035 14.3 1.5 1.4 1 0 0 1 1 1 0 Diaminopimelate epimerase VWA_2 PF13519.6 KXL44219.1 - 4.6e-20 72.3 0.0 2.1e-19 70.2 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 KXL44219.1 - 7.4e-05 23.1 0.0 0.00011 22.5 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 KXL44219.1 - 0.018 14.9 0.0 0.024 14.4 0.0 1.1 1 0 0 1 1 1 0 Ssl1-like Aldo_ket_red PF00248.21 KXL44221.1 - 4.1e-52 177.2 0.0 4.7e-52 177.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SKI PF01202.22 KXL44221.1 - 0.19 11.9 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase Sec2p PF06428.11 KXL44222.1 - 9.6e-28 96.0 26.0 1.7e-27 95.2 17.0 2.4 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Myosin_tail_1 PF01576.19 KXL44222.1 - 0.0046 14.9 21.9 0.007 14.2 21.9 1.2 1 0 0 1 1 1 1 Myosin tail Tup_N PF08581.10 KXL44222.1 - 0.053 13.8 19.6 0.91 9.9 3.5 3.4 1 1 1 2 2 2 0 Tup N-terminal NPV_P10 PF05531.12 KXL44222.1 - 0.26 11.8 4.4 0.32 11.5 0.5 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ADIP PF11559.8 KXL44222.1 - 0.29 11.2 28.0 0.42 10.7 17.7 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.10 KXL44222.1 - 0.36 11.0 14.7 1.4 9.1 4.8 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KXL44222.1 - 0.47 10.5 14.0 2.1 8.4 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 KXL44222.1 - 0.48 9.3 28.8 0.89 8.4 1.7 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein HMMR_N PF15905.5 KXL44222.1 - 0.52 9.7 24.2 0.85 9.0 24.2 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Sec8_exocyst PF04048.14 KXL44222.1 - 0.73 9.7 12.8 2 8.3 4.7 2.3 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain Golgin_A5 PF09787.9 KXL44222.1 - 0.73 9.2 24.1 1.1 8.7 24.1 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF3584 PF12128.8 KXL44222.1 - 1 6.8 25.1 2.6 5.5 24.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) SNARE PF05739.19 KXL44222.1 - 1.1 9.3 3.4 0.71 9.9 0.1 2.3 2 0 0 2 2 2 0 SNARE domain GCN5L1 PF06320.13 KXL44222.1 - 1.2 9.3 14.6 0.2 11.8 9.9 2.1 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) ATG16 PF08614.11 KXL44222.1 - 1.3 9.2 26.6 4.5 7.4 18.4 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FUSC PF04632.12 KXL44222.1 - 2.7 6.4 8.4 4.8 5.6 8.4 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Prominin PF05478.11 KXL44222.1 - 3.5 5.5 10.1 5.1 4.9 10.1 1.1 1 0 0 1 1 1 0 Prominin DUF4407 PF14362.6 KXL44222.1 - 4.5 6.5 13.2 7.7 5.8 13.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 KXL44222.1 - 5 6.1 20.0 11 5.0 20.0 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HR1 PF02185.16 KXL44222.1 - 6.9 6.9 21.3 2.6 8.2 12.9 2.6 2 1 0 2 2 2 0 Hr1 repeat Torus PF16131.5 KXL44223.1 - 3.1e-09 37.5 1.0 1.6e-05 25.6 0.1 2.7 2 0 0 2 2 2 2 Torus domain zf-CCCH PF00642.24 KXL44223.1 - 2.3e-08 33.7 12.6 1e-06 28.5 4.5 3.4 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KXL44223.1 - 2.1e-06 27.6 21.9 0.0013 18.7 4.8 3.5 3 0 0 3 3 3 2 Zinc finger domain SLATT_5 PF18160.1 KXL44223.1 - 6.6 6.0 5.6 2.8 7.2 1.1 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 HAD PF12710.7 KXL44224.1 - 7.5e-20 72.1 0.1 1e-19 71.7 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXL44224.1 - 7.3e-16 59.1 0.1 1.7e-15 57.9 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KXL44224.1 - 1e-08 35.3 0.1 5.9e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXL44224.1 - 0.0016 18.6 0.0 0.14 12.2 0.0 2.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF705 PF05152.12 KXL44224.1 - 0.18 11.2 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) FAD_binding_7 PF03441.14 KXL44225.1 - 1.3e-54 184.8 0.6 1.3e-54 184.8 0.6 1.6 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KXL44225.1 - 4.8e-38 130.8 0.0 8.1e-38 130.0 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Glycos_transf_1 PF00534.20 KXL44225.1 - 0.062 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 SNARE PF05739.19 KXL44226.1 - 4.9e-11 42.4 0.1 4.9e-11 42.4 0.1 2.6 3 0 0 3 3 3 1 SNARE domain Syntaxin-5_N PF11416.8 KXL44226.1 - 2.4e-10 39.3 0.3 6.3e-10 38.0 0.3 1.8 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 KXL44226.1 - 0.00033 20.4 3.7 0.0018 18.0 0.2 2.7 2 1 0 2 2 2 1 Syntaxin TRPM_tetra PF16519.5 KXL44226.1 - 0.021 14.9 0.1 0.082 13.0 0.1 2.0 1 0 0 1 1 1 0 Tetramerisation domain of TRPM Syntaxin-18_N PF10496.9 KXL44226.1 - 0.096 12.9 0.3 1.2 9.4 0.0 2.5 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus DUF1664 PF07889.12 KXL44226.1 - 0.15 12.1 2.6 1.6 8.8 0.2 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.6 KXL44226.1 - 0.3 11.5 5.2 0.85 10.1 0.1 3.4 3 1 0 3 3 3 0 Snapin/Pallidin DUF16 PF01519.16 KXL44226.1 - 0.49 10.9 8.5 0.17 12.4 1.2 2.6 2 1 0 2 2 2 0 Protein of unknown function DUF16 BLOC1_2 PF10046.9 KXL44226.1 - 1.8 8.9 4.4 2.8 8.3 1.5 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RmuC PF02646.16 KXL44226.1 - 2.6 7.1 6.5 10 5.2 0.1 3.1 3 0 0 3 3 3 0 RmuC family MCPsignal PF00015.21 KXL44226.1 - 3.6 7.4 7.8 0.42 10.4 0.9 2.3 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Use1 PF09753.9 KXL44226.1 - 5.4 6.7 6.6 0.45 10.2 0.4 2.3 3 0 0 3 3 3 0 Membrane fusion protein Use1 Spc7 PF08317.11 KXL44226.1 - 6.4 5.6 7.7 1.7 7.4 0.9 2.4 2 1 0 2 2 2 0 Spc7 kinetochore protein Git3 PF11710.8 KXL44228.1 - 5.1e-21 75.4 15.7 1.3e-20 74.1 15.7 1.6 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KXL44228.1 - 4.7e-07 29.8 0.1 1.6e-06 28.0 0.1 2.0 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term DUF5336 PF17270.2 KXL44228.1 - 0.026 14.2 0.2 0.063 12.9 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5336) 7TM_GPCR_Srsx PF10320.9 KXL44228.1 - 0.036 13.4 8.9 0.052 12.9 8.9 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Fumarate_red_D PF02313.17 KXL44228.1 - 2.2 8.4 10.9 1 9.5 2.8 2.6 2 0 0 2 2 2 0 Fumarate reductase subunit D Slu7 PF11708.8 KXL44229.1 - 5.5e-75 252.6 18.0 5.5e-75 252.6 18.0 2.3 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC PF00098.23 KXL44229.1 - 0.0032 17.5 1.7 0.006 16.6 1.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 KXL44229.1 - 0.0039 16.9 0.3 0.0091 15.7 0.3 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 KXL44229.1 - 0.079 12.8 2.5 0.17 11.7 2.5 1.5 1 0 0 1 1 1 0 Zinc knuckle RRM_1 PF00076.22 KXL44230.1 - 1.5e-05 24.7 0.0 0.00013 21.7 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RED_N PF07808.13 KXL44230.1 - 0.0067 16.0 1.1 0.022 14.4 0.1 2.1 2 0 0 2 2 2 1 RED-like protein N-terminal region GSK-3_bind PF05350.12 KXL44230.1 - 0.037 13.3 0.6 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 Glycogen synthase kinase-3 binding MFS_1 PF07690.16 KXL44231.1 - 1.4e-28 99.9 40.5 1.4e-28 99.9 40.5 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL44231.1 - 3.4e-10 39.4 10.7 3.4e-10 39.4 10.7 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXL44231.1 - 0.00053 18.5 0.9 0.00053 18.5 0.9 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) LacY_symp PF01306.19 KXL44231.1 - 0.00082 18.3 3.7 0.00082 18.3 3.7 1.9 2 1 0 2 2 2 1 LacY proton/sugar symporter RRM_1 PF00076.22 KXL44232.1 - 2.4e-14 52.9 0.0 4.5e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXL44232.1 - 0.012 15.8 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif AIRC PF00731.20 KXL44234.1 - 1.6e-56 190.0 1.5 2e-56 189.7 1.5 1.0 1 0 0 1 1 1 1 AIR carboxylase PrpR_N PF06506.11 KXL44234.1 - 0.0089 15.6 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Propionate catabolism activator DUF4781 PF16013.5 KXL44234.1 - 0.88 8.3 2.5 1.2 7.9 2.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4781) GFO_IDH_MocA PF01408.22 KXL44235.1 - 1.6e-17 64.5 0.0 2.6e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KXL44235.1 - 0.00092 19.9 0.2 0.0015 19.2 0.2 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Complex1_LYR PF05347.15 KXL44237.1 - 1.4e-18 66.7 3.8 1.8e-18 66.3 3.8 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KXL44237.1 - 5.6e-05 23.8 2.9 6.8e-05 23.5 2.9 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KXL44237.1 - 0.00097 19.7 0.4 0.0011 19.5 0.4 1.2 1 0 0 1 1 1 1 Complex1_LYR-like SVIP PF15811.5 KXL44237.1 - 0.001 19.5 1.1 0.0015 18.9 1.1 1.3 1 0 0 1 1 1 1 Small VCP/p97-interacting protein IL28A PF15177.6 KXL44237.1 - 0.063 13.1 0.9 0.076 12.9 0.9 1.1 1 0 0 1 1 1 0 Interleukin-28A PglL_A PF15864.5 KXL44237.1 - 0.076 12.8 0.7 0.13 12.0 0.7 1.3 1 0 0 1 1 1 0 Protein glycosylation ligase E3_UFM1_ligase PF09743.9 KXL44238.1 - 0.00063 19.4 0.1 0.011 15.4 0.0 2.7 2 1 0 2 2 2 1 E3 UFM1-protein ligase 1 DUF4191 PF13829.6 KXL44239.1 - 0.0041 16.5 0.6 0.11 11.8 0.2 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4191) MFS_1 PF07690.16 KXL44240.1 - 1.1e-29 103.5 26.9 1.1e-29 103.5 26.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily NUP PF06516.11 KXL44241.1 - 7.7e-127 422.8 1.2 8.7e-127 422.6 1.2 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Dimer_Tnp_hAT PF05699.14 KXL44242.1 - 0.039 13.7 0.1 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region DAO PF01266.24 KXL44244.1 - 3.9e-34 118.8 0.0 4.6e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXL44244.1 - 6.4e-06 26.3 0.0 2.3e-05 24.5 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXL44244.1 - 2.1e-05 23.8 0.0 3.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.20 KXL44244.1 - 0.004 17.2 0.0 0.0069 16.5 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 KXL44244.1 - 0.0044 17.0 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KXL44244.1 - 0.011 15.0 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 KXL44244.1 - 0.018 14.7 0.1 0.17 11.5 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Glu_dehyd_C PF16912.5 KXL44244.1 - 0.027 14.0 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Pyr_redox_2 PF07992.14 KXL44244.1 - 0.033 13.4 0.0 0.14 11.4 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXL44244.1 - 0.033 13.3 0.0 2.2 7.3 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A ThiF PF00899.21 KXL44244.1 - 0.038 13.3 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 ThiF family Pyr_redox_3 PF13738.6 KXL44244.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXL44244.1 - 0.19 12.3 0.0 0.69 10.5 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GYF PF02213.16 KXL44245.1 - 3.9e-17 61.6 0.7 8.5e-17 60.6 0.7 1.6 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 KXL44245.1 - 0.0096 15.7 0.3 0.024 14.4 0.3 1.7 1 0 0 1 1 1 1 GYF domain 2 B12D PF06522.11 KXL44245.1 - 0.17 11.7 0.0 0.68 9.8 0.0 2.0 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Atg14 PF10186.9 KXL44246.1 - 0.00048 19.3 3.5 0.056 12.5 0.2 2.2 2 0 0 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 GAS PF13851.6 KXL44246.1 - 0.0028 17.0 2.2 0.015 14.6 0.0 2.1 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Shugoshin_N PF07558.11 KXL44246.1 - 0.026 14.4 0.7 0.059 13.2 0.7 1.6 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region SlyX PF04102.12 KXL44246.1 - 0.034 14.8 5.8 0.95 10.1 0.1 2.5 2 0 0 2 2 2 0 SlyX DivIC PF04977.15 KXL44246.1 - 0.039 13.7 0.1 0.039 13.7 0.1 1.9 2 0 0 2 2 2 0 Septum formation initiator TMCO5 PF14992.6 KXL44246.1 - 0.044 13.4 0.1 0.044 13.4 0.1 1.5 2 0 0 2 2 2 0 TMCO5 family DUF5320 PF17253.2 KXL44246.1 - 0.047 14.8 0.8 0.18 12.9 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Spc24 PF08286.11 KXL44246.1 - 0.1 12.8 1.2 2.5 8.4 0.2 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Pox_A_type_inc PF04508.12 KXL44246.1 - 0.61 10.0 3.2 1.4 8.9 3.2 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DUF2615 PF11027.8 KXL44246.1 - 0.68 10.1 5.6 4.2 7.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) DASH_Spc34 PF08657.10 KXL44246.1 - 0.78 9.5 9.7 9.5 5.9 0.1 2.5 2 1 0 2 2 2 0 DASH complex subunit Spc34 HOOK PF05622.12 KXL44246.1 - 1.6 6.8 5.2 0.28 9.3 0.2 1.9 2 0 0 2 2 2 0 HOOK protein DUF2046 PF09755.9 KXL44246.1 - 2.4 7.3 8.5 0.31 10.2 0.2 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein H4 (DUF2046) DUF2968 PF11180.8 KXL44246.1 - 3.8 7.1 11.1 1.4 8.5 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Dicty_REP PF05086.12 KXL44246.1 - 4.5 5.1 6.0 7.7 4.4 6.0 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MerR-DNA-bind PF09278.11 KXL44246.1 - 6.7 7.3 8.0 0.3 11.7 0.3 2.2 2 0 0 2 2 2 0 MerR, DNA binding MFS_1 PF07690.16 KXL44249.1 - 5.2e-26 91.4 34.2 8.1e-26 90.8 34.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXL44249.1 - 3.8e-06 25.6 8.0 7.4e-06 24.7 8.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Methyltransf_2 PF00891.18 KXL44250.1 - 1.5e-20 73.4 0.0 4.4e-20 71.9 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase domain COBRA PF04833.15 KXL44251.1 - 0.012 15.6 1.0 0.3 11.0 0.1 2.8 3 0 0 3 3 3 0 COBRA-like protein SpoIID PF08486.10 KXL44251.1 - 0.13 12.9 0.1 0.21 12.1 0.1 1.4 1 0 0 1 1 1 0 Stage II sporulation protein NiFe_hyd_3_EhaA PF17367.2 KXL44251.1 - 0.18 12.0 2.2 0.68 10.1 0.6 2.5 2 1 1 3 3 3 0 NiFe-hydrogenase-type-3 Eha complex subunit A ADH_zinc_N PF00107.26 KXL44254.1 - 1.9e-11 44.1 0.3 2.8e-11 43.5 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXL44254.1 - 2.1e-05 24.4 0.7 0.00012 21.9 0.0 2.3 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXL44254.1 - 0.0056 17.7 0.0 0.0089 17.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Myc_N PF01056.18 KXL44255.1 - 0.0016 18.4 1.7 0.0016 18.4 1.7 1.2 1 0 0 1 1 1 1 Myc amino-terminal region Ribosomal_60s PF00428.19 KXL44255.1 - 0.0024 18.4 0.6 0.003 18.1 0.6 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3169 PF11368.8 KXL44255.1 - 0.012 15.2 0.1 0.014 14.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) FAM176 PF14851.6 KXL44255.1 - 0.023 14.4 1.3 0.029 14.0 1.3 1.2 1 0 0 1 1 1 0 FAM176 family Radial_spoke PF04712.12 KXL44255.1 - 0.036 13.0 5.4 0.039 12.9 5.4 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein HTH_psq PF05225.16 KXL44256.1 - 0.00017 21.3 0.8 0.00022 20.9 0.8 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain zf-RING_2 PF13639.6 KXL44257.1 - 2.4e-13 50.2 8.0 2.4e-13 50.2 8.0 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 KXL44257.1 - 8.6e-10 38.2 3.3 8.6e-10 38.2 3.3 2.6 3 0 0 3 3 3 1 RING-like zinc finger zf-rbx1 PF12678.7 KXL44257.1 - 6.7e-09 35.9 6.3 6.7e-09 35.9 6.3 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KXL44257.1 - 1.3e-08 34.6 10.3 3e-07 30.2 6.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXL44257.1 - 1.7e-08 34.2 4.9 1.7e-08 34.2 4.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXL44257.1 - 4e-08 33.0 7.2 4e-08 33.0 7.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXL44257.1 - 9.7e-08 31.9 6.7 1.7e-07 31.2 3.0 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXL44257.1 - 1.3e-06 28.2 5.3 1.3e-06 28.2 5.3 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KXL44257.1 - 0.00027 20.9 2.2 0.00061 19.8 2.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KXL44257.1 - 0.00034 20.7 9.4 0.0082 16.3 4.7 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING DUF4451 PF14616.6 KXL44257.1 - 0.0022 18.2 1.7 0.7 10.1 0.0 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4451) Zn_ribbon_17 PF17120.5 KXL44257.1 - 0.0034 17.0 8.8 0.022 14.4 8.8 2.1 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KXL44257.1 - 0.0048 16.7 11.3 0.015 15.2 7.7 2.6 2 1 1 3 3 2 2 Prokaryotic RING finger family 4 FANCL_C PF11793.8 KXL44257.1 - 0.0074 16.4 4.1 0.0074 16.4 4.1 1.8 2 0 0 2 2 1 1 FANCL C-terminal domain RINGv PF12906.7 KXL44257.1 - 0.022 14.9 9.5 0.022 14.9 9.5 1.9 2 0 0 2 2 1 0 RING-variant domain Takusan PF04822.13 KXL44257.1 - 0.031 14.2 0.4 0.94 9.4 0.0 2.7 2 0 0 2 2 2 0 Takusan zf-Nse PF11789.8 KXL44257.1 - 0.048 13.5 0.5 0.12 12.2 0.5 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 KXL44257.1 - 1.1 9.1 7.6 0.33 10.8 4.2 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain PHD PF00628.29 KXL44257.1 - 5.4 7.0 10.6 0.91 9.5 5.9 2.1 2 0 0 2 2 2 0 PHD-finger Rick_17kDa_Anti PF05433.15 KXL44258.1 - 0.00039 20.2 19.7 0.00085 19.1 19.7 1.6 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 KXL44258.1 - 0.081 12.9 15.0 0.17 11.9 15.0 1.6 1 0 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.6 KXL44258.1 - 0.086 12.6 14.4 0.16 11.7 14.4 1.5 1 0 0 1 1 1 0 YMGG-like Gly-zipper DUF533 PF04391.12 KXL44258.1 - 0.1 12.1 0.2 0.14 11.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF533) TraT PF05818.12 KXL44258.1 - 0.4 10.3 5.4 0.59 9.8 5.4 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein MDM31_MDM32 PF08118.11 KXL44259.1 - 0.58 8.8 0.9 0.76 8.4 0.9 1.1 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins DUF3270 PF11674.8 KXL44259.1 - 2.8 8.2 5.7 4.4 7.6 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) TatD_DNase PF01026.21 KXL44260.1 - 1.1e-31 110.1 0.0 2.2e-31 109.2 0.0 1.5 1 1 0 1 1 1 1 TatD related DNase Glyco_tranf_2_3 PF13641.6 KXL44262.1 - 1.2e-30 107.1 0.0 1.6e-30 106.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KXL44262.1 - 3.7e-08 33.4 0.0 7e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KXL44262.1 - 1.4e-07 31.1 0.0 7.7e-07 28.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 21 DUF3391 PF11871.8 KXL44264.1 - 0.043 14.4 3.4 0.16 12.5 3.4 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) BRF1 PF07741.13 KXL44264.1 - 0.17 12.2 5.2 5.3 7.5 0.0 2.4 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Presenilin PF01080.17 KXL44264.1 - 0.47 9.1 2.3 0.54 9.0 2.3 1.2 1 0 0 1 1 1 0 Presenilin DUF2968 PF11180.8 KXL44266.1 - 0.015 15.0 1.7 0.02 14.6 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Metallophos PF00149.28 KXL44268.1 - 1.7e-36 126.6 0.1 2.7e-36 126.0 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KXL44268.1 - 2.7e-16 59.7 0.0 4.8e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain SOG2 PF10428.9 KXL44269.1 - 0.27 10.4 2.8 0.31 10.2 2.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Abhydrolase_6 PF12697.7 KXL44270.1 - 6e-15 56.4 0.0 8.1e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 KXL44270.1 - 2.5e-07 31.1 0.0 5e-07 30.1 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.20 KXL44270.1 - 9.7e-05 22.1 1.0 0.00023 20.9 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KXL44270.1 - 0.00051 19.0 0.0 0.003 16.5 0.0 1.9 2 0 0 2 2 2 1 Chlorophyllase enzyme DUF1749 PF08538.10 KXL44270.1 - 0.016 14.3 0.6 0.12 11.4 0.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1749) Abhydrolase_3 PF07859.13 KXL44270.1 - 0.032 14.1 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1057 PF06342.12 KXL44270.1 - 0.036 13.1 0.0 0.067 12.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) PGAP1 PF07819.13 KXL44270.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Ser_hydrolase PF06821.13 KXL44270.1 - 0.14 12.0 0.2 3.1 7.6 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase SQS_PSY PF00494.19 KXL44271.1 - 1.8e-33 116.2 0.0 2.6e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase Kinesin PF00225.23 KXL44272.1 - 3.3e-111 371.4 0.0 3.3e-111 371.4 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KXL44272.1 - 1.1e-27 96.7 0.0 5e-27 94.7 0.0 2.2 1 0 0 1 1 1 1 Microtubule binding Microtub_bind PF13931.6 KXL44272.1 - 2.2e-06 28.1 1.3 2.2e-06 28.1 1.3 4.6 4 0 0 4 4 4 1 Kinesin-associated microtubule-binding UPF0183 PF03676.14 KXL44273.1 - 1.5e-44 152.9 0.0 3.4e-31 108.9 0.0 2.8 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0183) GST_N_3 PF13417.6 KXL44274.1 - 6.8e-14 52.0 0.0 8.5e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXL44274.1 - 2.4e-11 43.8 0.0 3.9e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXL44274.1 - 1.1e-10 41.7 0.0 1.7e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 KXL44274.1 - 0.0012 19.6 0.0 0.0026 18.5 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain UvrD-helicase PF00580.21 KXL44276.1 - 3.2e-60 204.3 4.7 4.9e-59 200.4 2.5 2.6 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KXL44276.1 - 2e-59 201.8 0.0 4.2e-58 197.4 0.0 2.3 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KXL44276.1 - 1.4e-32 113.0 0.1 5.7e-32 111.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 KXL44276.1 - 6.2e-14 51.6 0.1 2.1e-13 49.8 0.0 2.0 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KXL44276.1 - 8.7e-09 35.4 1.0 9e-06 25.5 0.2 2.8 2 1 0 2 2 2 2 AAA domain AAA_11 PF13086.6 KXL44276.1 - 0.00081 19.3 0.1 0.0026 17.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXL44276.1 - 0.057 13.7 2.1 20 5.4 0.1 3.5 2 1 1 3 3 3 0 AAA domain AAA_12 PF13087.6 KXL44276.1 - 0.08 12.6 0.0 0.96 9.0 0.0 2.5 3 0 0 3 3 3 0 AAA domain Helicase_RecD PF05127.14 KXL44276.1 - 0.11 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Helicase T3SS_needle_E PF08988.10 KXL44276.1 - 2.2 8.5 4.4 4.8 7.4 0.0 3.4 4 0 0 4 4 4 0 Type III secretion system, cytoplasmic E component of needle RNA_pol_Rpb6 PF01192.22 KXL44278.1 - 4.2e-16 58.6 0.2 7.9e-16 57.7 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb6 zf-C2H2 PF00096.26 KXL44279.1 - 2.3e-35 119.1 49.6 0.00021 21.6 0.7 11.2 11 0 0 11 11 11 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXL44279.1 - 2.6e-23 80.7 44.4 0.036 14.9 0.7 11.3 11 0 0 11 11 11 8 C2H2-type zinc finger FOXP-CC PF16159.5 KXL44279.1 - 6.8e-10 39.4 28.9 0.0008 20.0 0.3 8.0 6 3 2 8 8 8 2 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 KXL44279.1 - 2.2e-09 37.3 47.0 0.00011 22.4 0.2 10.5 10 0 0 10 10 10 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KXL44279.1 - 6.2e-08 32.7 15.5 3.4 8.1 0.0 9.4 10 0 0 10 10 10 1 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KXL44279.1 - 1.9e-07 30.7 18.5 0.24 11.2 0.0 8.3 9 0 0 9 9 9 2 zinc-finger C2H2-type zf-met PF12874.7 KXL44279.1 - 1.4e-05 25.3 10.3 7.3 7.1 0.0 8.2 10 0 0 10 10 9 1 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KXL44279.1 - 0.00081 19.6 34.6 1.5 9.2 1.2 8.3 6 2 2 8 8 8 3 Drought induced 19 protein (Di19), zinc-binding zf_Hakai PF18408.1 KXL44279.1 - 0.002 17.8 18.1 0.27 11.0 0.2 6.8 7 0 0 7 7 7 2 C2H2 Hakai zinc finger domain zf-C2H2_3rep PF18868.1 KXL44279.1 - 0.0041 17.8 15.9 3.1 8.5 3.0 4.5 2 2 3 5 5 5 1 Zinc finger C2H2-type, 3 repeats zf_ZIC PF18366.1 KXL44279.1 - 0.056 13.5 20.5 11 6.2 0.7 8.0 6 2 3 9 9 9 0 Zic proteins zinc finger domain zf-C2H2_8 PF15909.5 KXL44279.1 - 0.088 13.1 17.1 7 7.0 0.3 6.0 2 2 1 5 5 5 0 C2H2-type zinc ribbon Sgf11 PF08209.11 KXL44279.1 - 0.094 12.3 2.4 0.59 9.7 2.4 2.5 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) zf-H2C2_5 PF13909.6 KXL44279.1 - 0.12 12.2 33.7 0.54 10.1 0.1 8.4 8 0 0 8 8 8 0 C2H2-type zinc-finger domain zf-C2H2_aberr PF17017.5 KXL44279.1 - 1.3 9.1 21.4 6.1 6.9 1.3 6.1 2 2 5 8 8 8 0 Aberrant zinc-finger Ogr_Delta PF04606.12 KXL44279.1 - 4.2 7.4 10.3 1.4 9.0 0.0 4.1 3 1 1 4 4 4 0 Ogr/Delta-like zinc finger zf-C2H2_12 PF18658.1 KXL44279.1 - 5.4 6.7 23.9 1 9.0 0.4 6.6 5 3 4 9 9 9 0 Zinc-finger C2H2-type DUF5321 PF17254.2 KXL44280.1 - 1.6e-47 160.9 1.3 1.8e-47 160.7 1.3 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5321) AbrB PF05145.12 KXL44281.1 - 0.022 13.7 0.4 0.028 13.4 0.4 1.1 1 0 0 1 1 1 0 Transition state regulatory protein AbrB DUF1279 PF06916.13 KXL44283.1 - 9.8e-23 80.5 0.0 1.5e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) HTH_29 PF13551.6 KXL44284.1 - 0.00046 20.1 0.1 0.00058 19.8 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 KXL44284.1 - 0.034 14.3 0.3 0.055 13.6 0.3 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 KXL44284.1 - 0.035 13.9 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain DDE_1 PF03184.19 KXL44285.1 - 5e-22 78.4 0.0 1e-21 77.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease KR PF08659.10 KXL44285.1 - 0.018 14.9 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 KR domain TPP_enzyme_M PF00205.22 KXL44288.1 - 0.0026 17.5 0.0 0.0051 16.6 0.0 1.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain RRM_1 PF00076.22 KXL44289.1 - 6e-15 54.8 0.0 1.1e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EMP24_GP25L PF01105.24 KXL44289.1 - 0.019 14.9 0.9 0.026 14.5 0.9 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF3450 PF11932.8 KXL44289.1 - 0.04 13.2 3.8 0.051 12.9 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) GPS2_interact PF15784.5 KXL44289.1 - 0.064 13.7 1.4 0.099 13.1 1.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Nup35_RRM_2 PF14605.6 KXL44289.1 - 0.068 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif NPV_P10 PF05531.12 KXL44289.1 - 0.078 13.5 0.1 0.13 12.8 0.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 KXL44289.1 - 0.44 9.4 3.7 0.57 9.0 3.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF724 PF05266.14 KXL44289.1 - 0.64 9.8 3.9 0.85 9.4 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4140 PF13600.6 KXL44289.1 - 1 9.9 3.5 1.6 9.2 3.5 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) APG6_N PF17675.1 KXL44289.1 - 3 8.4 8.7 3.9 8.0 8.7 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region HECT PF00632.25 KXL44290.1 - 1.4e-93 313.7 0.0 1.9e-93 313.3 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KXL44290.1 - 8e-34 115.4 18.6 1.2e-11 44.5 1.4 4.0 4 0 0 4 4 4 3 WW domain C2 PF00168.30 KXL44290.1 - 1.1e-19 70.6 0.0 2.7e-19 69.3 0.0 1.7 1 0 0 1 1 1 1 C2 domain SRRM_C PF15230.6 KXL44290.1 - 1.7 9.2 4.1 1.2 9.8 1.8 1.9 2 0 0 2 2 2 0 Serine/arginine repetitive matrix protein C-terminus Spt20 PF12090.8 KXL44290.1 - 4.1 7.0 11.8 25 4.4 0.0 2.6 3 0 0 3 3 3 0 Spt20 family TFIIA PF03153.13 KXL44290.1 - 4.6 7.1 13.2 1.5 8.7 9.5 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit adh_short_C2 PF13561.6 KXL44293.1 - 3.3e-48 164.3 0.1 2.4e-41 141.8 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL44293.1 - 2.3e-45 154.4 0.1 3e-45 154.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL44293.1 - 8.2e-17 61.7 0.1 1.2e-16 61.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL44293.1 - 1.4e-08 34.5 0.1 4.1e-08 33.0 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXL44293.1 - 0.017 14.6 0.0 0.062 12.7 0.0 2.1 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase PAF-AH_p_II PF03403.13 KXL44293.1 - 0.2 10.1 0.0 0.3 9.5 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II RskA PF10099.9 KXL44295.1 - 0.0085 16.4 0.1 0.013 15.8 0.1 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA JmjC PF02373.22 KXL44296.1 - 6.1e-10 39.5 1.2 7.1e-09 36.1 0.8 2.6 2 1 0 2 2 2 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 KXL44296.1 - 2e-06 27.9 7.2 2e-06 27.9 7.2 2.9 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.11 KXL44296.1 - 0.0024 17.6 0.0 0.0059 16.3 0.0 1.6 1 0 0 1 1 1 1 Cupin domain Zn_clus PF00172.18 KXL44297.1 - 8.2e-10 38.6 10.2 8.2e-10 38.6 10.2 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXL44297.1 - 9.7e-08 31.3 2.1 1.5e-07 30.7 2.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PNGaseA PF12222.8 KXL44298.1 - 1e-158 528.8 0.2 1.4e-158 528.3 0.2 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A PUMA PF15826.5 KXL44300.1 - 0.0021 18.3 1.5 0.0025 18.0 1.5 1.0 1 0 0 1 1 1 1 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis p450 PF00067.22 KXL44301.1 - 6.1e-58 196.7 0.0 9e-58 196.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 KXL44302.1 - 3.5e-41 141.3 0.0 4.9e-41 140.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL44302.1 - 3.4e-19 69.1 0.0 5.2e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXL44302.1 - 7e-05 22.9 0.0 0.066 13.1 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KXL44302.1 - 0.00029 20.2 0.0 0.0005 19.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXL44302.1 - 0.002 17.0 0.0 0.0026 16.6 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXL44302.1 - 0.015 14.6 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KXL44302.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 ELFV_dehydrog PF00208.21 KXL44303.1 - 6.9e-65 219.1 0.0 1.2e-64 218.4 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KXL44303.1 - 3.5e-19 67.9 0.0 3e-13 48.3 0.1 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 KXL44303.1 - 0.038 13.9 0.0 0.17 11.8 0.0 2.1 3 0 0 3 3 3 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Mito_carr PF00153.27 KXL44304.1 - 1.1e-73 243.2 5.6 8.1e-24 83.4 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXL44304.1 - 0.00053 19.2 2.2 0.096 11.8 0.1 3.5 3 1 1 4 4 4 2 Gammaproteobacterial serine protease PT-VENN PF04829.13 KXL44304.1 - 3.2 7.9 6.2 29 4.8 0.1 3.1 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif ARTD15_N PF18084.1 KXL44305.1 - 0.0063 16.7 0.1 0.01 16.1 0.1 1.3 1 0 0 1 1 1 1 ARTD15 N-terminal domain Proteasome PF00227.26 KXL44306.1 - 1.6e-47 161.5 0.4 2e-47 161.2 0.4 1.1 1 0 0 1 1 1 1 Proteasome subunit ubiquitin PF00240.23 KXL44307.1 - 8.4e-26 89.5 0.0 9.7e-26 89.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KXL44307.1 - 1.1e-11 44.4 0.0 1.2e-11 44.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 KXL44307.1 - 0.00042 20.2 0.0 0.00051 19.9 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 KXL44307.1 - 0.00045 20.6 0.0 0.0011 19.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KXL44307.1 - 0.14 12.2 0.0 0.68 10.1 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like MCM PF00493.23 KXL44308.1 - 4.8e-99 330.0 0.0 7.1e-99 329.4 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KXL44308.1 - 3.7e-39 133.5 1.2 7.2e-39 132.5 1.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KXL44308.1 - 3.1e-29 101.2 3.4 9.4e-29 99.7 3.4 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KXL44308.1 - 3.5e-14 53.2 0.2 1.6e-13 51.1 0.1 2.2 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 KXL44308.1 - 8.7e-06 25.8 0.1 6.3e-05 23.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KXL44308.1 - 1.2e-05 24.8 0.0 0.0003 20.3 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KXL44308.1 - 0.0016 18.3 0.0 0.004 17.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Elf1 PF05129.13 KXL44308.1 - 0.12 12.5 0.4 0.37 10.9 0.4 1.8 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like TBCA PF02970.16 KXL44309.1 - 1.7e-23 82.7 9.6 2.2e-23 82.4 9.6 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A 2_5_RNA_ligase2 PF13563.6 KXL44309.1 - 0.069 13.1 0.8 0.08 12.9 0.8 1.3 1 1 0 1 1 1 0 2'-5' RNA ligase superfamily Vir_act_alpha_C PF10400.9 KXL44309.1 - 0.15 12.8 3.8 0.12 13.1 2.3 1.6 1 1 1 2 2 2 0 Virulence activator alpha C-term DUF465 PF04325.13 KXL44309.1 - 0.21 11.6 5.5 0.43 10.6 4.8 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF465) RF-1 PF00472.20 KXL44309.1 - 2.2 8.2 12.2 0.32 11.0 2.2 2.1 1 1 0 2 2 2 0 RF-1 domain LMBR1 PF04791.16 KXL44309.1 - 4.4 6.1 4.2 4.8 6.0 4.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Elongin_A PF06881.11 KXL44310.1 - 1.7e-27 95.9 5.1 3.9e-27 94.8 5.1 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Evr1_Alr PF04777.13 KXL44311.1 - 2.3e-29 101.8 2.0 2.3e-29 101.8 2.0 1.7 2 0 0 2 2 2 1 Erv1 / Alr family HEM4 PF02602.15 KXL44312.1 - 1.5e-34 119.4 0.1 4.3e-34 117.9 0.1 1.7 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Omp_AT PF11557.8 KXL44312.1 - 0.13 11.2 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Solitary outer membrane autotransporter beta-barrel domain THOC7 PF05615.13 KXL44313.1 - 1.4e-35 122.4 12.5 1.4e-35 122.4 12.5 1.7 1 1 1 2 2 2 1 Tho complex subunit 7 Med9 PF07544.13 KXL44313.1 - 0.015 15.3 5.8 0.065 13.3 0.4 2.6 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 CTD PF12815.7 KXL44313.1 - 0.11 13.0 1.0 0.21 12.2 1.0 1.3 1 0 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 SGT1 PF07093.11 KXL44313.1 - 0.25 9.8 7.7 0.12 10.8 2.8 1.7 1 1 1 2 2 2 0 SGT1 protein DivIC PF04977.15 KXL44313.1 - 0.27 11.0 0.1 0.27 11.0 0.1 2.6 2 1 0 2 2 2 0 Septum formation initiator DUF4200 PF13863.6 KXL44313.1 - 0.37 11.2 14.8 0.82 10.1 14.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) HAUS6_N PF14661.6 KXL44313.1 - 0.49 9.9 11.6 1.5 8.4 11.5 1.8 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Golgin_A5 PF09787.9 KXL44313.1 - 0.58 9.6 13.2 0.99 8.8 13.2 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 TMPIT PF07851.13 KXL44313.1 - 1.1 8.5 2.4 1.5 8.0 2.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein KfrA_N PF11740.8 KXL44313.1 - 1.1 10.0 12.4 4.7 7.9 5.8 2.7 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term PCRF PF03462.18 KXL44313.1 - 1.4 8.7 7.1 3 7.6 7.1 1.5 1 0 0 1 1 1 0 PCRF domain FUSC PF04632.12 KXL44313.1 - 1.7 7.1 6.5 2.2 6.7 6.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Enkurin PF13864.6 KXL44313.1 - 2.6 8.5 10.2 6.9 7.2 10.2 1.7 1 0 0 1 1 1 0 Calmodulin-binding Fib_alpha PF08702.10 KXL44313.1 - 8.9 6.5 8.3 15 5.8 3.2 2.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family MPLKIP PF15502.6 KXL44314.1 - 0.0015 18.7 2.0 0.0029 17.8 1.0 2.1 1 1 1 2 2 2 1 M-phase-specific PLK1-interacting protein Methyltransf_23 PF13489.6 KXL44315.1 - 1.3e-17 64.2 0.0 1.8e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL44315.1 - 1.9e-11 44.5 0.0 5.1e-11 43.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL44315.1 - 1.2e-09 38.7 0.0 2.6e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL44315.1 - 2.5e-09 37.1 0.0 2.9e-08 33.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL44315.1 - 1.9e-08 35.0 0.0 7.2e-08 33.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KXL44315.1 - 0.00076 18.8 0.0 0.0021 17.4 0.0 1.7 2 0 0 2 2 2 1 O-methyltransferase domain MTS PF05175.14 KXL44315.1 - 0.00077 19.0 0.0 0.0036 16.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KXL44315.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF1100 PF06500.11 KXL44316.1 - 8.7e-17 61.0 0.0 1.2e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Esterase PF00756.20 KXL44316.1 - 9.9e-07 28.6 0.3 8.4e-06 25.6 0.3 2.1 1 1 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 KXL44316.1 - 4.7e-06 27.4 0.1 8.3e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXL44316.1 - 0.00016 21.4 0.1 0.00046 19.9 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXL44316.1 - 0.00074 18.9 0.0 0.0011 18.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 KXL44316.1 - 0.0032 17.4 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal USP8_dimer PF08969.11 KXL44316.1 - 0.0046 17.1 0.4 0.01 16.0 0.2 1.6 2 0 0 2 2 1 1 USP8 dimerisation domain Peptidase_S9 PF00326.21 KXL44316.1 - 0.012 15.1 0.0 0.035 13.6 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KXL44316.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 KXL44316.1 - 0.014 15.0 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) MIT PF04212.18 KXL44316.1 - 0.11 12.6 0.3 0.25 11.4 0.3 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Esterase_phd PF10503.9 KXL44316.1 - 0.19 11.2 0.0 0.43 10.0 0.0 1.5 2 0 0 2 2 2 0 Esterase PHB depolymerase OST3_OST6 PF04756.13 KXL44319.1 - 9.7e-105 350.1 0.0 1.2e-104 349.8 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family QCR10 PF09796.9 KXL44319.1 - 0.53 10.4 3.2 6.1 7.0 0.1 3.0 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) CPBP PF02517.16 KXL44319.1 - 4.2 7.8 5.8 10 6.5 5.6 1.9 1 1 0 1 1 1 0 CPBP intramembrane metalloprotease Hexokinase_2 PF03727.16 KXL44320.1 - 6.9e-82 274.5 0.0 9e-82 274.1 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KXL44320.1 - 5.7e-71 238.5 0.0 1.5e-70 237.2 0.0 1.6 2 0 0 2 2 2 1 Hexokinase IATP PF04568.12 KXL44321.1 - 1.2e-21 77.0 4.3 1.4e-21 76.7 4.3 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP FUSC PF04632.12 KXL44321.1 - 0.78 8.2 3.7 0.92 8.0 3.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1003 PF06210.11 KXL44321.1 - 0.96 9.6 3.7 1.4 9.0 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Ribosomal_L19e PF01280.20 KXL44322.1 - 4.8e-61 205.0 6.7 4.8e-61 205.0 6.7 1.9 1 1 1 2 2 2 1 Ribosomal protein L19e OmdA PF13376.6 KXL44322.1 - 0.06 13.4 1.2 0.06 13.4 1.2 2.8 2 1 1 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated TRAP-gamma PF07074.12 KXL44322.1 - 0.85 9.2 3.8 1.1 8.8 3.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Gcn1_N PF12074.8 KXL44323.1 - 3.7e-115 385.1 0.6 1.4e-112 376.6 0.1 3.8 3 0 0 3 3 3 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT_EZ PF13513.6 KXL44323.1 - 3.8e-30 103.9 49.4 3e-06 27.6 0.0 19.4 17 3 4 21 21 19 8 HEAT-like repeat HEAT_2 PF13646.6 KXL44323.1 - 3.5e-27 94.6 45.3 2.2e-05 24.7 0.0 15.0 10 4 3 15 15 14 7 HEAT repeats HEAT PF02985.22 KXL44323.1 - 2.8e-26 89.3 42.3 0.14 12.5 0.0 21.3 23 0 0 23 23 22 6 HEAT repeat Cnd1 PF12717.7 KXL44323.1 - 8.2e-16 58.5 7.8 0.013 15.5 0.1 9.6 5 2 2 9 9 9 2 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 KXL44323.1 - 4.3e-13 49.8 0.0 0.00074 19.7 0.0 6.4 5 1 2 7 7 7 2 Parkin co-regulated protein Vac14_Fab1_bd PF12755.7 KXL44323.1 - 7.5e-12 45.7 0.0 0.41 11.3 0.0 9.4 9 3 3 12 12 9 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KXL44323.1 - 1.2e-08 34.8 0.0 0.61 9.6 0.0 6.2 5 1 1 6 6 6 2 CLASP N terminal UME PF08064.13 KXL44323.1 - 5.7e-07 29.4 0.2 2.5 8.0 0.0 8.2 8 1 1 9 9 9 1 UME (NUC010) domain Adaptin_N PF01602.20 KXL44323.1 - 8.5e-06 24.6 9.8 0.012 14.2 0.9 6.5 5 2 0 5 5 5 2 Adaptin N terminal region TIP120 PF08623.10 KXL44323.1 - 0.0037 17.1 0.0 3.1 7.5 0.0 4.5 3 1 1 4 4 4 1 TATA-binding protein interacting (TIP20) MMS19_C PF12460.8 KXL44323.1 - 0.015 14.4 0.1 0.015 14.4 0.1 8.6 8 2 3 11 11 11 0 RNAPII transcription regulator C-terminal DUF3080 PF11279.8 KXL44323.1 - 0.035 13.3 0.1 0.12 11.6 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) RasGEF_N_2 PF14663.6 KXL44323.1 - 0.037 14.4 0.1 15 6.0 0.0 4.6 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF937 PF06078.11 KXL44323.1 - 0.054 14.1 11.6 90 3.7 0.1 6.6 6 2 0 6 6 4 0 Bacterial protein of unknown function (DUF937) Ecm29 PF13001.7 KXL44323.1 - 0.079 11.6 5.0 1.6 7.3 0.1 4.4 3 1 1 5 5 5 0 Proteasome stabiliser MMS19_N PF14500.6 KXL44323.1 - 0.15 11.6 11.5 9.5 5.7 0.3 7.4 9 0 0 9 9 9 0 Dos2-interacting transcription regulator of RNA-Pol-II RIX1 PF08167.12 KXL44323.1 - 0.16 11.7 7.8 0.75 9.5 0.2 5.3 5 0 0 5 5 4 0 rRNA processing/ribosome biogenesis RTP1_C1 PF10363.9 KXL44323.1 - 0.21 11.8 12.1 22 5.3 0.0 7.6 9 0 0 9 9 9 0 Required for nuclear transport of RNA pol II C-terminus 1 Tti2 PF10521.9 KXL44323.1 - 0.26 10.8 9.2 3.8 7.0 0.0 5.5 7 0 0 7 7 7 0 Tti2 family HEAT_PBS PF03130.16 KXL44323.1 - 2 9.3 24.5 1.5e+02 3.5 0.0 11.2 11 1 0 11 11 10 0 PBS lyase HEAT-like repeat Cohesin_HEAT PF12765.7 KXL44323.1 - 4.7 7.6 13.2 2.8 8.3 0.0 6.5 7 0 0 7 7 6 0 HEAT repeat associated with sister chromatid cohesion Cytochrom_B561 PF03188.16 KXL44324.1 - 5.2e-17 62.3 4.3 8.9e-17 61.5 4.3 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 KXL44324.1 - 0.0011 19.2 15.5 0.002 18.3 1.2 3.3 1 1 2 3 3 3 2 Protein of unknown function (DUF4079) Phage_holin_1 PF04531.13 KXL44324.1 - 2.8 8.5 7.2 11 6.7 0.5 3.1 3 0 0 3 3 3 0 Bacteriophage holin Putative_PNPOx PF01243.20 KXL44325.1 - 0.00017 21.7 0.0 0.00033 20.8 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase TMEM132D_C PF15706.5 KXL44325.1 - 0.23 11.2 0.4 0.41 10.4 0.4 1.3 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term PLDc PF00614.22 KXL44326.1 - 9.7e-15 54.1 3.9 3.9e-08 33.2 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KXL44326.1 - 2.8e-13 49.9 0.0 0.00011 22.1 0.0 3.5 3 0 0 3 3 3 3 PLD-like domain Pyr_redox_2 PF07992.14 KXL44327.1 - 1.5e-10 40.8 0.0 2.2e-09 37.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXL44327.1 - 0.0029 17.8 0.0 0.012 15.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXL44327.1 - 0.012 14.8 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 KXL44327.1 - 0.059 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding DAO PF01266.24 KXL44329.1 - 7.1e-57 193.6 0.0 8.3e-57 193.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXL44329.1 - 5.2e-06 26.6 0.7 1.1e-05 25.5 0.7 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 KXL44329.1 - 0.0038 16.9 0.3 0.0065 16.1 0.3 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 KXL44329.1 - 0.012 14.9 0.6 0.018 14.3 0.6 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXL44329.1 - 0.015 14.6 0.2 0.024 13.9 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KXL44329.1 - 0.04 13.3 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KXL44329.1 - 0.046 14.0 0.2 0.079 13.2 0.2 1.3 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 KXL44329.1 - 0.079 12.8 0.4 0.66 9.8 0.5 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KXL44329.1 - 0.093 12.7 0.4 0.15 12.0 0.4 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.17 KXL44329.1 - 0.093 12.0 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 KXL44329.1 - 0.11 11.8 0.2 0.15 11.3 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KXL44329.1 - 0.11 13.1 0.3 0.29 11.7 0.3 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXL44329.1 - 0.17 10.9 0.6 0.28 10.2 0.6 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Aldo_ket_red PF00248.21 KXL44330.1 - 2.4e-69 233.8 0.0 2.8e-69 233.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3341 PF11821.8 KXL44331.1 - 0.13 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) SPX PF03105.19 KXL44332.1 - 5.1 6.9 10.0 6.4 6.6 10.0 1.1 1 0 0 1 1 1 0 SPX domain ATP-synt_B PF00430.18 KXL44333.1 - 1.4 9.0 8.1 1.7 8.7 6.8 1.6 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) Mo-co_dimer PF03404.16 KXL44334.1 - 8.5e-60 200.7 0.0 1.5e-59 199.9 0.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 KXL44334.1 - 3.7e-54 182.9 0.0 6.5e-54 182.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 KXL44334.1 - 8.8e-33 112.6 0.0 1.8e-32 111.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KXL44334.1 - 1.1e-26 93.6 0.0 2.2e-26 92.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 KXL44334.1 - 3.9e-21 75.0 0.0 1.2e-20 73.4 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KXL44334.1 - 0.0088 16.2 0.0 0.07 13.2 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain PC_rep PF01851.22 KXL44334.1 - 0.1 13.1 0.0 0.48 11.0 0.0 2.2 2 0 0 2 2 2 0 Proteasome/cyclosome repeat Pyr_redox_2 PF07992.14 KXL44335.1 - 4.2e-40 137.8 0.0 7.4e-40 137.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 KXL44335.1 - 8e-20 71.0 0.0 1.4e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Rieske_2 PF13806.6 KXL44335.1 - 5.4e-16 58.4 0.0 2.6e-15 56.2 0.0 2.1 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Pyr_redox PF00070.27 KXL44335.1 - 1e-15 58.0 0.8 3.3e-15 56.4 0.8 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 KXL44335.1 - 6.7e-14 52.0 7.2 2.6e-11 43.7 4.3 2.8 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rieske PF00355.26 KXL44335.1 - 7.6e-14 51.4 0.1 3.1e-13 49.5 0.0 2.1 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.17 KXL44335.1 - 6.9e-12 45.0 0.0 1.9e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 KXL44335.1 - 2.6e-05 24.1 0.1 0.085 12.8 0.0 3.3 3 0 0 3 3 3 2 Rubredoxin NAD+ reductase C-terminal domain Pyr_redox_3 PF13738.6 KXL44335.1 - 5.9e-05 22.5 0.0 9.2e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXL44335.1 - 0.00033 20.1 0.6 0.024 13.9 0.0 2.3 1 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KXL44335.1 - 0.053 13.5 0.1 4.9 7.1 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 KXL44335.1 - 0.15 11.1 0.9 7.2 5.6 0.3 2.9 2 1 1 3 3 3 0 Glucose inhibited division protein A Methyltransf_32 PF13679.6 KXL44339.1 - 0.04 13.9 0.0 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KXL44339.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 KXL44339.1 - 0.18 11.9 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase BTB PF00651.31 KXL44341.1 - 4.1e-08 33.4 0.0 6.4e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain AAA PF00004.29 KXL44342.1 - 4.1e-10 40.2 0.0 8.5e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KXL44342.1 - 2.6e-05 24.2 0.2 0.00024 21.1 0.0 2.1 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_5 PF07728.14 KXL44342.1 - 6.7e-05 22.9 0.0 0.00015 21.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KXL44342.1 - 0.0001 22.1 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KXL44342.1 - 0.0045 17.2 0.0 0.015 15.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KXL44342.1 - 0.0054 16.7 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 KXL44342.1 - 0.0076 16.5 0.0 0.035 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXL44342.1 - 0.015 15.7 0.0 0.058 13.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.6 KXL44342.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXL44342.1 - 0.15 12.7 0.1 0.33 11.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KXL44342.1 - 0.15 12.0 0.1 0.35 10.8 0.1 1.6 1 0 0 1 1 1 0 NTPase La PF05383.17 KXL44344.1 - 4.6e-19 68.2 0.0 8.7e-19 67.3 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KXL44344.1 - 7.8e-09 35.2 0.1 1.6e-08 34.2 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3449 PF11931.8 KXL44344.1 - 0.049 13.4 1.2 1.8 8.3 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) S4 PF01479.25 KXL44345.1 - 4.1e-13 48.8 0.0 8.7e-13 47.8 0.0 1.6 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 KXL44345.1 - 0.078 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 S4 domain Pex19 PF04614.12 KXL44345.1 - 0.11 12.2 6.1 0.18 11.6 6.1 1.3 1 0 0 1 1 1 0 Pex19 protein family Cellulase PF00150.18 KXL44346.1 - 3e-06 26.9 1.2 0.00015 21.3 0.0 2.2 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Ysc84 PF04366.12 KXL44348.1 - 3.2e-48 162.7 0.0 4.8e-48 162.1 0.0 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator Acetyltransf_1 PF00583.25 KXL44349.1 - 5.1e-06 26.7 0.0 8.1e-06 26.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXL44349.1 - 6.6e-06 26.5 0.0 1.5e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXL44349.1 - 0.00096 19.2 0.0 0.04 14.0 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXL44349.1 - 0.0011 18.9 0.0 0.0032 17.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Methyltransf_16 PF10294.9 KXL44350.1 - 0.0041 16.9 0.0 0.32 10.7 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase adh_short PF00106.25 KXL44351.1 - 8.1e-23 80.9 0.0 6.3e-18 64.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXL44351.1 - 2.1e-15 56.9 0.0 2.6e-14 53.4 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL44351.1 - 0.0026 17.7 0.1 0.0055 16.6 0.1 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL44351.1 - 0.011 15.2 0.0 0.16 11.4 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXL44351.1 - 0.012 15.0 0.0 0.083 12.3 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase VCH_CASS14 PF18315.1 KXL44352.1 - 0.028 14.5 0.1 0.28 11.2 0.0 2.6 2 1 1 3 3 3 0 Integron cassette protein VCH_CASS1 chain ADH_zinc_N PF00107.26 KXL44353.1 - 1.1e-28 99.8 0.0 2.4e-28 98.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXL44353.1 - 4.1e-11 44.1 0.0 7e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXL44353.1 - 2.3e-06 27.5 0.0 1.1e-05 25.2 0.0 2.2 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KXL44353.1 - 0.029 13.7 0.2 0.042 13.1 0.2 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ubiquitin PF00240.23 KXL44354.1 - 7.4e-20 70.5 0.0 1e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KXL44354.1 - 2.2e-06 27.4 0.0 4e-06 26.6 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 KXL44354.1 - 4.2e-06 26.8 0.1 7.2e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KXL44354.1 - 9.8e-06 26.1 0.0 1.6e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Mucin PF01456.17 KXL44355.1 - 0.13 12.2 9.5 0.32 11.0 9.5 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein Vta1 PF04652.16 KXL44355.1 - 0.96 9.4 3.8 1.5 8.8 0.4 2.3 1 1 1 2 2 2 0 Vta1 like ADH_N PF08240.12 KXL44356.1 - 1.6e-26 92.3 1.8 4e-26 91.0 1.8 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXL44356.1 - 1.2e-14 54.4 0.0 1.9e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXL44356.1 - 7.6e-07 28.8 0.4 0.00016 21.2 0.4 2.6 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 KXL44356.1 - 0.043 13.4 0.0 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GFO_IDH_MocA PF01408.22 KXL44357.1 - 2.4e-17 63.8 0.0 3.6e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF3136 PF11334.8 KXL44357.1 - 0.0096 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3136) Pmp3 PF01679.17 KXL44358.1 - 2.8e-13 49.8 6.6 4.3e-13 49.3 6.6 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator AMP-binding PF00501.28 KXL44359.1 - 1.5e-07 30.4 0.0 1.6e-07 30.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Nucleopor_Nup85 PF07575.13 KXL44360.1 - 1.8e-18 66.5 1.7 6.7e-11 41.5 0.4 3.3 3 1 0 3 3 3 2 Nup85 Nucleoporin Glyco_hydro_127 PF07944.12 KXL44361.1 - 8.1e-105 351.2 0.0 9.4e-105 351.0 0.0 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Sugar_tr PF00083.24 KXL44362.1 - 2.7e-77 260.5 26.6 3.2e-77 260.3 26.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL44362.1 - 2.8e-11 43.0 38.4 5.6e-10 38.7 13.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4605 PF15378.6 KXL44362.1 - 0.23 11.3 2.2 0.35 10.7 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4605) FAD_binding_3 PF01494.19 KXL44363.1 - 6.3e-87 292.1 0.0 9.7e-87 291.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KXL44363.1 - 3.5e-52 176.8 0.1 6.5e-52 175.9 0.1 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Fungal_trans PF04082.18 KXL44363.1 - 5e-12 45.4 0.1 1.2e-11 44.2 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL44363.1 - 7.2e-06 26.0 12.1 1.7e-05 24.8 12.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_3 PF13738.6 KXL44363.1 - 0.0015 17.8 0.1 0.0025 17.1 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXL44363.1 - 0.0023 17.2 0.0 0.012 14.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXL44363.1 - 0.0055 16.9 0.0 0.03 14.5 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXL44363.1 - 0.0074 15.0 0.1 0.015 14.0 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KXL44363.1 - 0.057 12.5 0.1 0.099 11.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 KXL44363.1 - 0.14 11.2 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Dioxygenase_C PF00775.21 KXL44364.1 - 5.6e-45 153.0 0.0 7.7e-45 152.6 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KXL44364.1 - 5e-28 96.8 0.1 8.1e-28 96.1 0.1 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KXL44364.1 - 1e-05 25.7 0.0 0.00091 19.4 0.0 2.6 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KXL44364.1 - 0.025 14.6 0.2 11 6.1 0.0 3.8 4 0 0 4 4 4 0 CarboxypepD_reg-like domain FAD_binding_3 PF01494.19 KXL44365.1 - 1.1e-07 31.4 0.0 1.4e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain RNA_pol_Rpb2_6 PF00562.28 KXL44366.1 - 5.5e-125 417.5 0.1 7.8e-125 417.0 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KXL44366.1 - 4.8e-57 192.8 0.0 7.4e-57 192.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KXL44366.1 - 8.9e-43 146.1 0.1 1.9e-42 145.1 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KXL44366.1 - 2.3e-31 108.0 0.1 4.8e-31 107.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 KXL44366.1 - 1.1e-25 89.6 0.1 2.4e-25 88.5 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 KXL44366.1 - 1.4e-22 79.7 0.2 3.5e-22 78.5 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 KXL44366.1 - 1.9e-20 73.2 0.2 4.5e-20 72.0 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Ran_BP1 PF00638.18 KXL44367.1 - 2.7e-15 56.7 0.0 4.5e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain RecA PF00154.21 KXL44368.1 - 6.3e-06 25.8 0.0 9.1e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 KXL44368.1 - 6e-05 22.4 0.0 0.0001 21.7 0.0 1.4 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KXL44368.1 - 0.055 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KXL44368.1 - 0.2 11.5 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MOSC PF03473.17 KXL44369.1 - 1.7e-24 86.3 0.0 3.1e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KXL44369.1 - 8.7e-12 45.0 0.0 2.1e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain DUF2418 PF10332.9 KXL44371.1 - 2.5e-32 111.3 0.0 5.5e-32 110.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) DHO_dh PF01180.21 KXL44372.1 - 6.1e-63 212.8 0.1 2.2e-52 178.1 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase TRAM1 PF08390.11 KXL44372.1 - 0.18 11.4 0.1 0.39 10.4 0.1 1.5 1 0 0 1 1 1 0 TRAM1-like protein YjeF_N PF03853.15 KXL44373.1 - 9.1e-34 116.8 0.0 1.1e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Porin_1 PF00267.21 KXL44373.1 - 0.012 15.0 0.0 0.016 14.7 0.0 1.1 1 0 0 1 1 1 0 Gram-negative porin Torsin PF06309.11 KXL44373.1 - 0.12 12.5 0.0 4.3 7.4 0.0 2.2 2 0 0 2 2 2 0 Torsin Amino_oxidase PF01593.24 KXL44373.1 - 0.12 11.6 0.0 8.7 5.5 0.0 2.3 1 1 1 2 2 2 0 Flavin containing amine oxidoreductase DprA_WH PF17782.1 KXL44373.1 - 0.13 12.4 0.1 0.32 11.2 0.1 1.7 1 0 0 1 1 1 0 DprA winged helix domain ETC_C1_NDUFA5 PF04716.14 KXL44374.1 - 3.7e-27 93.9 5.3 5.8e-26 90.1 0.2 2.6 3 0 0 3 3 3 2 ETC complex I subunit conserved region Thioredoxin PF00085.20 KXL44375.1 - 9.2e-45 150.9 0.1 3.4e-24 84.8 0.0 4.3 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KXL44375.1 - 4.8e-12 46.2 0.0 1.8e-05 24.7 0.0 4.2 3 1 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KXL44375.1 - 8e-08 32.5 1.2 0.0099 16.2 0.0 3.6 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KXL44375.1 - 1.7e-07 31.7 1.3 0.046 14.2 0.1 3.9 3 1 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KXL44375.1 - 7.2e-06 25.6 0.1 0.0081 15.6 0.1 2.4 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family HyaE PF07449.11 KXL44375.1 - 0.0079 16.2 0.0 1.9 8.5 0.0 3.1 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.21 KXL44375.1 - 0.015 15.2 0.1 0.74 9.7 0.0 2.8 3 0 0 3 3 3 0 AhpC/TSA family Thioredoxin_7 PF13899.6 KXL44375.1 - 0.017 15.3 1.8 0.096 12.9 0.1 2.9 3 0 0 3 3 3 0 Thioredoxin-like TraF PF13728.6 KXL44375.1 - 0.093 12.5 3.6 3.7 7.3 0.0 3.3 4 0 0 4 4 4 0 F plasmid transfer operon protein Ribosomal_S17e PF00833.18 KXL44376.1 - 2.8e-61 204.8 1.3 3.4e-61 204.6 1.3 1.1 1 0 0 1 1 1 1 Ribosomal S17 GUCT PF08152.12 KXL44376.1 - 0.031 14.6 0.0 0.045 14.1 0.0 1.3 1 1 0 1 1 1 0 GUCT (NUC152) domain SMC_N PF02463.19 KXL44377.1 - 2.3e-61 207.1 12.8 2.4e-60 203.7 12.8 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KXL44377.1 - 1.3e-20 73.9 0.5 1.6e-19 70.3 0.1 2.8 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KXL44377.1 - 8e-11 42.3 0.8 6.5e-05 22.9 0.3 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KXL44377.1 - 2.6e-05 24.8 42.3 2.6e-05 24.8 42.3 7.9 3 2 0 3 3 1 1 AAA domain AAA_13 PF13166.6 KXL44377.1 - 0.0005 18.9 32.8 0.0005 18.9 32.8 5.5 3 2 2 5 5 5 3 AAA domain AAA_29 PF13555.6 KXL44377.1 - 0.00053 19.7 0.1 0.0013 18.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain GAS PF13851.6 KXL44377.1 - 0.00064 19.1 3.7 0.00064 19.1 3.7 7.4 4 1 2 7 7 7 3 Growth-arrest specific micro-tubule binding MscS_porin PF12795.7 KXL44377.1 - 0.00066 19.3 26.5 0.00066 19.3 26.5 7.7 3 2 4 7 7 5 1 Mechanosensitive ion channel porin domain Cnn_1N PF07989.11 KXL44377.1 - 0.0033 17.6 3.1 0.0033 17.6 3.1 11.3 5 4 4 11 11 9 1 Centrosomin N-terminal motif 1 Spc7 PF08317.11 KXL44377.1 - 0.0037 16.2 20.2 0.0037 16.2 20.2 7.5 2 2 5 7 7 7 2 Spc7 kinetochore protein FlxA PF14282.6 KXL44377.1 - 0.0088 16.0 3.2 0.0088 16.0 3.2 8.0 5 1 3 8 8 6 1 FlxA-like protein AAA_5 PF07728.14 KXL44377.1 - 0.094 12.7 1.7 0.62 10.0 0.7 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF2999 PF11212.8 KXL44377.1 - 0.47 10.8 4.0 0.79 10.0 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2999) Yippee-Mis18 PF03226.14 KXL44378.1 - 0.097 12.9 1.0 0.2 11.9 1.0 1.6 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly GalP_UDP_transf PF01087.22 KXL44380.1 - 9.4e-69 231.5 0.1 2.6e-67 226.8 0.0 2.2 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 KXL44380.1 - 3.8e-59 199.2 0.2 8.9e-59 198.0 0.1 1.6 1 1 1 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF4921 PF16268.5 KXL44380.1 - 0.018 13.9 0.1 0.28 10.0 0.0 2.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4921) WG_beta_rep PF14903.6 KXL44380.1 - 0.059 13.7 0.1 0.13 12.6 0.1 1.5 1 0 0 1 1 1 0 WG containing repeat TPP_enzyme_N PF02776.18 KXL44381.1 - 2.2e-12 46.9 0.3 3.5e-12 46.3 0.3 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KXL44381.1 - 6.8e-10 38.9 0.0 1.6e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXL44381.1 - 0.0087 15.8 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Rad4 PF03835.15 KXL44382.1 - 6.9e-35 119.9 0.1 6.9e-35 119.9 0.1 2.7 3 0 0 3 3 3 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KXL44382.1 - 6.1e-29 100.2 0.1 1.2e-28 99.3 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KXL44382.1 - 1.7e-15 56.6 0.1 4.3e-15 55.3 0.1 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KXL44382.1 - 6.1e-15 55.9 2.3 6.1e-15 55.9 2.3 5.0 6 0 0 6 6 6 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KXL44382.1 - 0.015 15.7 0.0 0.059 13.8 0.0 2.0 1 0 0 1 1 1 0 Transglutaminase-like superfamily Ku_C PF03730.14 KXL44382.1 - 3.7 8.3 7.2 1 10.1 1.3 3.2 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm SlyX PF04102.12 KXL44382.1 - 4.9 7.9 6.8 0.7 10.6 1.2 2.4 2 0 0 2 2 2 0 SlyX Mit_ribos_Mrp51 PF11709.8 KXL44383.1 - 1.1e-109 367.4 0.5 1.3e-109 367.1 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit Ecl1 PF12855.7 KXL44383.1 - 0.88 10.7 3.4 0.6 11.3 1.0 1.9 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins Peptidase_M3 PF01432.20 KXL44384.1 - 4.7e-159 530.5 0.6 6e-159 530.2 0.6 1.1 1 0 0 1 1 1 1 Peptidase family M3 U-box PF04564.15 KXL44385.1 - 2.2e-19 69.4 0.0 5.1e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 U-box domain TPR_1 PF00515.28 KXL44385.1 - 1.4e-10 40.5 4.0 0.0044 16.8 0.7 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXL44385.1 - 5.4e-09 35.5 5.1 0.009 16.1 0.5 4.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KXL44385.1 - 1.5e-08 34.8 1.5 4.8e-05 23.6 0.2 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXL44385.1 - 6.4e-07 29.9 4.6 0.00015 22.4 0.0 3.4 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXL44385.1 - 1.5e-06 28.6 0.3 0.006 17.1 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXL44385.1 - 4.8e-06 26.7 0.3 0.073 13.3 0.1 2.4 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 CHIP_TPR_N PF18391.1 KXL44385.1 - 4.7e-05 24.1 4.6 7.9e-05 23.4 4.6 1.3 1 0 0 1 1 1 1 CHIP N-terminal tetratricopeptide repeat domain zf-Nse PF11789.8 KXL44385.1 - 0.0006 19.6 0.2 0.0018 18.0 0.1 1.7 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit TPR_7 PF13176.6 KXL44385.1 - 0.00064 19.6 0.2 3.6 7.8 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXL44385.1 - 0.0035 17.6 3.6 0.048 14.0 0.1 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat zf-NOSIP PF15906.5 KXL44385.1 - 0.0072 16.4 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein TPR_8 PF13181.6 KXL44385.1 - 0.036 14.3 2.1 5.1 7.6 0.3 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KXL44385.1 - 0.14 11.9 3.9 0.27 11.0 0.1 3.2 2 1 1 3 3 3 0 TPR repeat TPR_14 PF13428.6 KXL44385.1 - 0.34 11.9 9.0 3.1 8.8 0.0 4.4 3 2 2 5 5 4 0 Tetratricopeptide repeat Acetyltransf_6 PF13480.7 KXL44385.1 - 0.63 10.2 4.3 1.1 9.4 4.3 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TPR_4 PF07721.14 KXL44385.1 - 0.95 10.3 0.1 0.95 10.3 0.1 3.0 4 0 0 4 4 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXL44385.1 - 4.4 7.3 6.5 8.2 6.4 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Thymidylat_synt PF00303.19 KXL44386.1 - 1.1e-104 349.4 0.0 1.2e-104 349.2 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase AAA PF00004.29 KXL44387.1 - 1.3e-36 125.9 0.0 1e-35 123.1 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXL44387.1 - 4.1e-09 36.1 0.0 9.6e-09 34.9 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KXL44387.1 - 8.1e-06 25.7 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXL44387.1 - 2.5e-05 24.7 2.2 0.00048 20.6 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.6 KXL44387.1 - 6e-05 23.1 0.0 0.00018 21.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 KXL44387.1 - 0.00017 21.7 0.0 0.00036 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KXL44387.1 - 0.00023 21.2 0.1 0.002 18.1 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXL44387.1 - 0.00036 20.8 0.1 0.012 15.9 0.0 2.7 2 1 1 3 3 2 1 AAA domain AAA_33 PF13671.6 KXL44387.1 - 0.00062 19.9 0.0 0.0014 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 KXL44387.1 - 0.0011 18.4 0.0 1.7 8.0 0.0 2.6 1 1 1 2 2 2 2 Bacterial TniB protein AAA_25 PF13481.6 KXL44387.1 - 0.0014 18.2 0.1 0.12 11.9 0.1 2.4 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KXL44387.1 - 0.002 17.6 0.1 0.0039 16.6 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KXL44387.1 - 0.0025 18.3 0.0 0.0063 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KXL44387.1 - 0.0047 16.7 0.0 0.0085 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KXL44387.1 - 0.0057 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KXL44387.1 - 0.0066 16.8 0.0 0.018 15.4 0.0 1.9 1 1 0 1 1 1 1 RNA helicase NACHT PF05729.12 KXL44387.1 - 0.011 15.6 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.26 KXL44387.1 - 0.014 15.1 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.6 KXL44387.1 - 0.017 15.4 0.3 0.056 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KXL44387.1 - 0.033 14.1 0.0 0.11 12.4 0.0 1.8 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 KXL44387.1 - 0.042 14.4 0.0 0.096 13.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 KXL44387.1 - 0.049 13.2 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region CPT PF07931.12 KXL44387.1 - 0.075 12.9 0.0 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DUF815 PF05673.13 KXL44387.1 - 0.077 12.2 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 KXL44387.1 - 0.089 12.0 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.12 KXL44387.1 - 0.095 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Viral_helicase1 PF01443.18 KXL44387.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 KXL44387.1 - 0.14 11.5 0.0 0.79 9.0 0.0 2.0 1 1 1 2 2 2 0 KaiC TsaE PF02367.17 KXL44387.1 - 0.14 12.1 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 KXL44387.1 - 0.16 11.1 0.0 0.34 10.1 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain PGA2 PF07543.12 KXL44387.1 - 0.78 9.7 5.4 1.4 8.9 0.9 2.3 2 0 0 2 2 2 0 Protein trafficking PGA2 Methyltransf_8 PF05148.15 KXL44388.1 - 1.5e-57 195.0 0.1 7.1e-55 186.2 0.0 3.0 2 2 1 3 3 3 2 Hypothetical methyltransferase Methyltransf_11 PF08241.12 KXL44388.1 - 8.6e-06 26.3 0.0 4.5e-05 24.0 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL44388.1 - 0.00057 20.5 0.0 0.035 14.8 0.0 3.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL44388.1 - 0.0053 16.6 0.0 0.7 9.7 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 KXL44388.1 - 0.086 12.4 0.0 4.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase small domain Nucleo_P87 PF07267.11 KXL44390.1 - 3.4 6.4 7.7 15 4.3 0.0 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 LON_substr_bdg PF02190.16 KXL44391.1 - 8e-32 110.8 0.0 1.3e-31 110.2 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KXL44391.1 - 5.7e-22 78.6 0.0 1.3e-21 77.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Lon_C PF05362.13 KXL44391.1 - 3.4e-20 72.5 0.0 5.9e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA_5 PF07728.14 KXL44391.1 - 3.5e-06 27.1 0.0 7e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXL44391.1 - 9.8e-06 25.9 1.6 0.00017 21.9 0.2 3.0 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 KXL44391.1 - 9.1e-05 22.6 0.0 0.00027 21.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KXL44391.1 - 0.00025 20.8 0.0 0.0017 18.1 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXL44391.1 - 0.0007 20.0 0.4 0.0007 20.0 0.4 2.9 3 1 0 3 3 2 1 AAA ATPase domain AAA_PrkA PF08298.11 KXL44391.1 - 0.00097 18.1 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 PrkA AAA domain IstB_IS21 PF01695.17 KXL44391.1 - 0.0021 17.8 0.0 0.0052 16.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 KXL44391.1 - 0.0047 17.5 0.0 0.016 15.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXL44391.1 - 0.0076 16.0 0.0 0.023 14.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KXL44391.1 - 0.04 13.9 0.0 0.077 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXL44391.1 - 0.048 14.1 0.0 0.18 12.2 0.0 1.9 2 0 0 2 2 2 0 RNA helicase F-box-like_2 PF13013.6 KXL44391.1 - 0.073 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 F-box-like domain zf-C4H2 PF10146.9 KXL44391.1 - 0.085 13.2 0.2 0.085 13.2 0.2 1.9 2 0 0 2 2 2 0 Zinc finger-containing protein TIP49 PF06068.13 KXL44391.1 - 0.091 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain RecG_wedge PF17191.4 KXL44391.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 RecG wedge domain Rad17 PF03215.15 KXL44391.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_33 PF13671.6 KXL44391.1 - 0.12 12.5 0.1 0.32 11.1 0.1 1.8 1 0 0 1 1 1 0 AAA domain SKI PF01202.22 KXL44391.1 - 0.14 12.3 0.5 0.36 11.0 0.1 1.9 2 0 0 2 2 2 0 Shikimate kinase TetR_C_29 PF17938.1 KXL44391.1 - 0.16 12.0 0.0 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain NTPase_1 PF03266.15 KXL44391.1 - 0.18 11.7 0.1 1.9 8.4 0.1 2.5 2 1 1 3 3 3 0 NTPase RsgA_GTPase PF03193.16 KXL44391.1 - 0.19 11.7 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 KXL44391.1 - 0.19 11.7 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Spt20 PF12090.8 KXL44391.1 - 2.4 7.7 4.0 5.5 6.5 0.7 2.2 2 0 0 2 2 2 0 Spt20 family Hexapep_2 PF14602.6 KXL44392.1 - 1e-14 54.0 13.4 7.6e-10 38.4 0.4 2.6 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 KXL44392.1 - 1e-12 47.2 10.7 3.5e-09 36.0 1.1 3.5 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 KXL44392.1 - 5.9e-12 45.6 0.3 1.1e-11 44.8 0.3 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase DUF2040 PF09745.9 KXL44393.1 - 1.2e-36 125.4 19.4 1.2e-36 125.4 19.4 3.0 3 0 0 3 3 3 2 Coiled-coil domain-containing protein 55 (DUF2040) AP_endonuc_2 PF01261.24 KXL44393.1 - 0.0087 15.5 0.4 0.014 14.8 0.4 1.5 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Ku PF02735.16 KXL44394.1 - 2.5e-39 135.1 0.0 4.6e-39 134.3 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KXL44394.1 - 1.5e-30 106.6 0.0 2.3e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 KXL44394.1 - 8.4e-24 84.1 1.1 1.1e-23 83.7 0.0 1.8 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm Ish1 PF10281.9 KXL44394.1 - 0.1 12.9 0.1 0.22 11.9 0.1 1.6 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Methyltransf_23 PF13489.6 KXL44395.1 - 3.9e-15 56.1 0.0 5e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL44395.1 - 5.1e-11 43.2 0.0 8.1e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL44395.1 - 6.1e-10 39.6 0.0 9.2e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL44395.1 - 2.1e-09 38.0 0.0 3e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL44395.1 - 7.5e-06 25.8 0.0 2.2e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 KXL44395.1 - 0.094 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Ferrochelatase PF00762.19 KXL44396.1 - 3.5e-100 335.1 0.0 7.2e-100 334.1 0.0 1.5 1 1 0 1 1 1 1 Ferrochelatase PRP38 PF03371.15 KXL44398.1 - 4.3e-56 189.5 0.0 5.6e-56 189.1 0.0 1.1 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.7 KXL44398.1 - 1.3 9.7 10.9 0.11 13.1 6.2 1.6 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Ycf66_N PF07444.11 KXL44399.1 - 0.14 12.3 0.1 0.14 12.3 0.1 2.1 2 0 0 2 2 2 0 Ycf66 protein N-terminus Dynamin_N PF00350.23 KXL44400.1 - 6.5e-14 52.3 0.0 3.3e-13 50.1 0.0 2.2 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KXL44400.1 - 9.7e-07 28.9 0.0 0.00096 19.2 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase ABC_tran PF00005.27 KXL44400.1 - 7.3e-05 23.3 0.1 0.00064 20.2 0.0 2.6 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 KXL44400.1 - 0.0023 17.8 1.2 0.0086 16.0 0.1 2.4 2 1 1 3 3 3 1 RsgA GTPase AIG1 PF04548.16 KXL44400.1 - 0.0028 17.0 0.2 0.017 14.5 0.1 2.3 2 0 0 2 2 2 1 AIG1 family AAA_16 PF13191.6 KXL44400.1 - 0.0029 18.0 0.0 0.012 16.0 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain IIGP PF05049.13 KXL44400.1 - 0.0064 15.6 2.3 0.17 10.9 0.1 3.0 2 2 1 3 3 3 1 Interferon-inducible GTPase (IIGP) Roc PF08477.13 KXL44400.1 - 0.019 15.2 0.0 0.09 13.0 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF1043 PF06295.12 KXL44400.1 - 0.13 12.3 3.7 0.34 10.9 1.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) ILVD_EDD PF00920.21 KXL44401.1 - 4e-210 698.8 0.0 4.6e-210 698.6 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family FMO-like PF00743.19 KXL44402.1 - 3.3e-15 55.5 0.0 1.5e-14 53.4 0.0 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXL44402.1 - 2.4e-12 46.7 0.0 2.8e-11 43.2 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXL44402.1 - 2.6e-10 40.0 0.0 4.4e-08 32.7 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXL44402.1 - 9.9e-08 32.1 0.0 2.5e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXL44402.1 - 3.9e-07 30.0 0.0 4.5e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KXL44402.1 - 5.1e-07 29.2 0.2 0.00015 21.1 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 KXL44402.1 - 0.00041 20.4 0.0 0.075 13.1 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 KXL44402.1 - 0.00059 19.2 0.1 0.0012 18.1 0.1 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KXL44402.1 - 0.0045 17.0 0.0 0.016 15.2 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KXL44402.1 - 0.0076 15.4 0.1 0.014 14.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KXL44402.1 - 0.074 13.6 0.0 24 5.6 0.0 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3445 PF11927.8 KXL44403.1 - 1.1e-71 241.1 0.0 1.3e-71 240.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Chromo PF00385.24 KXL44404.1 - 0.006 16.5 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain E2F_TDP PF02319.20 KXL44404.1 - 0.13 12.3 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 E2F/DP family winged-helix DNA-binding domain Aldedh PF00171.22 KXL44405.1 - 1.8e-161 537.8 0.0 2e-161 537.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KXL44405.1 - 0.00017 21.1 0.0 0.58 9.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) G_glu_transpept PF01019.21 KXL44405.1 - 0.094 11.5 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase p450 PF00067.22 KXL44406.1 - 4.2e-70 236.8 0.0 5.3e-70 236.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.28 KXL44407.1 - 1e-88 297.8 0.0 1.3e-88 297.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXL44407.1 - 3.5e-13 50.3 0.2 8.1e-13 49.2 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short_C2 PF13561.6 KXL44408.1 - 1.6e-45 155.5 0.0 1.9e-45 155.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL44408.1 - 3.1e-40 137.7 0.1 4.6e-40 137.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL44408.1 - 5.4e-11 42.7 0.2 7.2e-11 42.3 0.2 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 KXL44408.1 - 0.021 14.6 0.2 0.21 11.4 0.2 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Tex_YqgF PF16921.5 KXL44408.1 - 0.06 13.8 0.1 7.3 7.1 0.0 2.2 2 0 0 2 2 2 0 Tex protein YqgF-like domain Tup_N PF08581.10 KXL44409.1 - 0.12 12.6 0.3 0.29 11.5 0.3 1.5 1 0 0 1 1 1 0 Tup N-terminal EthD PF07110.11 KXL44410.1 - 0.0041 18.2 0.1 2.8 9.2 0.0 2.4 2 0 0 2 2 2 2 EthD domain DUF4286 PF14114.6 KXL44410.1 - 0.076 13.5 4.2 0.51 10.9 0.0 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4286) ADH_zinc_N PF00107.26 KXL44411.1 - 2e-19 69.8 0.4 3.2e-19 69.2 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXL44411.1 - 7.2e-17 61.2 0.8 7.2e-17 61.2 0.8 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KXL44411.1 - 6.2e-05 22.4 0.2 8.7e-05 21.9 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KXL44411.1 - 0.00036 20.5 0.7 0.0006 19.7 0.7 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KXL44411.1 - 0.0013 18.2 0.1 0.0023 17.3 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KXL44411.1 - 0.0098 15.2 0.1 0.013 14.8 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase PglD_N PF17836.1 KXL44411.1 - 0.012 16.2 0.1 0.026 15.2 0.1 1.6 1 0 0 1 1 1 0 PglD N-terminal domain Methyltransf_25 PF13649.6 KXL44411.1 - 0.021 15.5 0.1 0.049 14.3 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KXL44411.1 - 0.03 15.0 0.1 0.061 14.0 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain BKACE PF05853.12 KXL44411.1 - 0.053 12.8 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme RimK PF08443.11 KXL44411.1 - 0.064 12.9 0.3 0.39 10.3 0.0 2.1 1 1 1 2 2 2 0 RimK-like ATP-grasp domain DUF5396 PF17374.2 KXL44411.1 - 0.073 10.9 0.0 0.096 10.5 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5396) TrkA_N PF02254.18 KXL44411.1 - 0.098 12.9 0.2 0.18 12.1 0.2 1.4 1 0 0 1 1 1 0 TrkA-N domain XdhC_C PF13478.6 KXL44411.1 - 0.14 12.6 0.1 0.21 12.1 0.1 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain EthD PF07110.11 KXL44412.1 - 4.4e-19 69.4 1.1 5.7e-19 69.1 1.1 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KXL44412.1 - 8.6e-07 29.4 0.3 1.2e-06 29.0 0.3 1.2 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase TRI12 PF06609.13 KXL44413.1 - 5.5e-44 150.6 17.8 7.1e-44 150.2 17.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KXL44413.1 - 1.8e-20 73.2 38.2 1.8e-20 73.2 38.2 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL44413.1 - 1.1e-07 31.0 8.6 1.1e-07 31.0 8.6 2.8 2 0 0 2 2 2 1 Sugar (and other) transporter DUF373 PF04123.13 KXL44413.1 - 0.035 13.5 2.9 0.037 13.5 1.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Glyco_hydro_18 PF00704.28 KXL44414.1 - 1.2e-19 71.2 1.2 2.3e-19 70.2 1.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Acyl-CoA_dh_1 PF00441.24 KXL44416.1 - 3.7e-24 85.7 0.2 6.3e-24 84.9 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXL44416.1 - 1e-12 48.7 0.0 2.1e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KXL44416.1 - 6.9e-07 29.4 0.0 1.6e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXL44416.1 - 6.9e-07 29.6 0.0 1.1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Epimerase PF01370.21 KXL44417.1 - 0.047 13.1 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family APH PF01636.23 KXL44418.1 - 9e-44 150.2 0.0 1.2e-43 149.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KXL44418.1 - 3.5e-07 29.8 0.0 5.4e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 KXL44418.1 - 0.00068 19.3 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KXL44418.1 - 0.0017 18.0 0.0 0.012 15.2 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Fructosamin_kin PF03881.14 KXL44418.1 - 0.0023 17.2 0.0 0.094 11.9 0.0 2.2 1 1 0 1 1 1 1 Fructosamine kinase Kdo PF06293.14 KXL44418.1 - 0.0061 15.9 0.0 0.017 14.4 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.11 KXL44418.1 - 0.043 12.7 0.0 0.083 11.7 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) AtuA PF07287.11 KXL44419.1 - 4.9e-131 436.6 0.1 5.9e-131 436.4 0.1 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA DUF5371 PF17341.2 KXL44419.1 - 0.13 12.5 0.0 0.65 10.2 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5371) RRM_1 PF00076.22 KXL44420.1 - 3.7e-08 33.1 0.0 6.8e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXL44420.1 - 2.5e-07 30.6 0.0 4.8e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KXL44420.1 - 0.0005 19.9 0.0 0.0021 17.9 0.0 2.0 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_3 PF08777.11 KXL44420.1 - 0.087 12.9 0.0 0.26 11.4 0.0 1.8 1 0 0 1 1 1 0 RNA binding motif Pro-kuma_activ PF09286.11 KXL44421.1 - 1.3e-49 168.2 0.0 5e-49 166.3 0.0 1.9 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KXL44421.1 - 0.0019 17.5 0.1 0.0031 16.8 0.1 1.2 1 0 0 1 1 1 1 Subtilase family SR-25 PF10500.9 KXL44422.1 - 8.7 5.9 18.3 14 5.2 18.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DAGK_cat PF00781.24 KXL44424.1 - 3.3e-15 55.8 0.0 4.7e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DASH_Duo1 PF08651.10 KXL44426.1 - 2.6e-26 91.2 0.2 3.6e-26 90.7 0.2 1.2 1 0 0 1 1 1 1 DASH complex subunit Duo1 DASH_Dad2 PF08654.10 KXL44426.1 - 0.0022 18.4 1.9 0.0047 17.3 1.9 1.6 1 1 0 1 1 1 1 DASH complex subunit Dad2 Macoilin PF09726.9 KXL44426.1 - 0.0049 15.5 2.0 0.006 15.2 2.0 1.1 1 0 0 1 1 1 1 Macoilin family Endonuc_Holl PF10107.9 KXL44426.1 - 0.16 11.8 2.4 0.23 11.3 2.4 1.3 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DUF1682 PF07946.14 KXL44426.1 - 0.26 10.4 3.2 0.31 10.2 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) API5 PF05918.11 KXL44426.1 - 0.55 9.0 2.6 0.65 8.7 2.6 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) FUSC PF04632.12 KXL44426.1 - 5.2 5.5 8.4 6.9 5.1 8.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family But2 PF09792.9 KXL44427.1 - 0.0046 17.4 0.1 0.011 16.1 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Tex_N PF09371.10 KXL44427.1 - 0.0067 16.1 0.2 0.21 11.2 0.0 2.2 2 0 0 2 2 2 1 Tex-like protein N-terminal domain RNR_inhib PF08591.10 KXL44427.1 - 0.28 12.5 0.1 0.28 12.5 0.1 2.8 2 1 0 2 2 2 0 Ribonucleotide reductase inhibitor TAA-Trp-ring PF15401.6 KXL44428.1 - 0.22 12.0 3.5 5.4 7.5 0.2 2.4 2 0 0 2 2 2 0 Tryptophan-ring motif of head of Trimeric autotransporter adhesin DUF4690 PF15756.5 KXL44431.1 - 0.48 11.1 2.1 0.44 11.2 0.4 1.7 2 0 0 2 2 2 0 Small Novel Rich in Cartilage BTB PF00651.31 KXL44432.1 - 1.3e-06 28.6 0.0 4.3e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain DUF4203 PF13886.6 KXL44433.1 - 0.0099 15.6 4.9 0.03 14.0 4.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Phage_holin_5_2 PF16079.5 KXL44433.1 - 1.1 9.6 5.7 7.9 6.9 0.1 3.0 3 1 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V ArsB PF02040.15 KXL44434.1 - 5.8e-08 32.5 24.4 2.8e-05 23.6 7.2 2.4 3 0 0 3 3 3 2 Arsenical pump membrane protein DUF347 PF03988.12 KXL44434.1 - 7.3 6.9 10.3 37 4.6 3.2 3.8 2 1 1 3 3 3 0 Repeat of Unknown Function (DUF347) UQ_con PF00179.26 KXL44435.1 - 5.5e-40 136.2 0.0 6.2e-40 136.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXL44435.1 - 8.9e-05 22.2 0.0 0.00012 21.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KXL44435.1 - 0.0003 21.1 0.0 0.00036 20.8 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 KXL44435.1 - 0.0089 15.9 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 UEV domain RabGAP-TBC PF00566.18 KXL44436.1 - 2.5e-33 115.6 0.0 4e-32 111.6 0.0 2.2 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Seipin PF06775.14 KXL44437.1 - 8.8e-56 189.1 0.2 1e-55 188.9 0.2 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) SPW PF03779.14 KXL44437.1 - 0.021 14.4 0.2 2.2 8.0 0.0 2.4 2 0 0 2 2 2 0 SPW repeat Cg6151-P PF10233.9 KXL44439.1 - 4e-44 149.6 16.3 4.7e-44 149.3 16.3 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P COPI_assoc PF08507.10 KXL44439.1 - 0.0046 17.0 15.3 0.0067 16.5 15.3 1.3 1 0 0 1 1 1 1 COPI associated protein DUF3784 PF12650.7 KXL44439.1 - 0.32 11.2 15.6 0.57 10.4 4.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) Dpy19 PF10034.9 KXL44439.1 - 3.6 5.7 10.9 4.3 5.4 10.9 1.0 1 0 0 1 1 1 0 Q-cell neuroblast polarisation UPF0139 PF03669.13 KXL44439.1 - 3.6 7.5 6.8 4.3 7.3 1.9 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) DUF2651 PF10852.8 KXL44439.1 - 5.7 7.6 17.5 0.13 12.9 5.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2651) Actin PF00022.19 KXL44440.1 - 9.4e-28 96.9 0.0 3.9e-16 58.7 0.0 2.3 2 0 0 2 2 2 2 Actin Actin_micro PF17003.5 KXL44440.1 - 1e-05 24.9 0.0 0.0003 20.1 0.0 2.1 2 0 0 2 2 2 1 Putative actin-like family MreB_Mbl PF06723.13 KXL44440.1 - 1.1e-05 24.4 0.0 2.6e-05 23.2 0.0 1.5 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KXL44440.1 - 0.0033 17.8 0.0 0.016 15.6 0.0 2.1 2 0 0 2 2 2 1 Cell division protein FtsA PilM_2 PF11104.8 KXL44440.1 - 0.2 10.6 0.0 0.46 9.5 0.0 1.5 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; NTF2 PF02136.20 KXL44441.1 - 1.7e-30 106.1 0.1 1.9e-30 105.9 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 KXL44441.1 - 0.00087 19.7 0.0 0.0011 19.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) TpcC PF12642.7 KXL44441.1 - 0.014 15.2 0.0 0.017 14.9 0.0 1.1 1 0 0 1 1 1 0 Conjugative transposon protein TcpC Methyltransf_23 PF13489.6 KXL44442.1 - 8.8e-22 77.7 0.0 1.3e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL44442.1 - 1.9e-13 50.9 0.0 5.9e-13 49.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL44442.1 - 2.8e-10 40.2 0.1 6.5e-09 35.8 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL44442.1 - 1.5e-09 38.4 0.0 3.9e-09 37.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL44442.1 - 9.4e-09 35.9 0.0 8.7e-08 32.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXL44442.1 - 1.2e-05 24.9 0.0 0.00015 21.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KXL44442.1 - 0.00046 19.7 0.0 0.018 14.5 0.0 2.8 3 0 0 3 3 3 1 Putative methyltransferase FtsJ PF01728.19 KXL44442.1 - 0.00059 20.0 0.0 0.0024 18.0 0.0 1.9 1 1 0 2 2 2 1 FtsJ-like methyltransferase PrmA PF06325.13 KXL44442.1 - 0.0084 15.5 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 KXL44442.1 - 0.014 14.7 0.0 0.034 13.4 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 KXL44442.1 - 0.04 13.2 0.0 0.18 11.0 0.0 1.9 2 0 0 2 2 2 0 O-methyltransferase domain Methyltransf_8 PF05148.15 KXL44442.1 - 0.1 12.4 0.0 0.27 11.0 0.0 1.6 1 1 0 1 1 1 0 Hypothetical methyltransferase PEP_mutase PF13714.6 KXL44443.1 - 4.1e-44 150.8 0.0 5.1e-44 150.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KXL44443.1 - 2.2e-15 56.2 0.2 3e-15 55.7 0.2 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Mem_trans PF03547.18 KXL44445.1 - 4.8e-24 84.5 0.0 7.1e-24 83.9 0.0 1.2 1 0 0 1 1 1 1 Membrane transport protein NapE PF06796.11 KXL44445.1 - 0.71 9.4 7.0 3.1 7.4 0.0 3.6 3 0 0 3 3 3 0 Periplasmic nitrate reductase protein NapE AA_permease_2 PF13520.6 KXL44446.1 - 4.1e-45 154.4 48.8 5.7e-45 153.9 48.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXL44446.1 - 3.6e-24 85.2 43.8 4.8e-24 84.8 43.8 1.1 1 0 0 1 1 1 1 Amino acid permease Aldedh PF00171.22 KXL44447.1 - 5.1e-15 54.9 0.0 5.3e-15 54.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FAD_binding_3 PF01494.19 KXL44449.1 - 1.1e-21 77.4 0.1 1.6e-21 76.9 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXL44449.1 - 8.8e-08 32.3 1.9 1.9e-07 31.2 1.2 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXL44449.1 - 1.3e-07 31.5 8.0 0.0083 15.7 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KXL44449.1 - 1e-06 27.7 1.0 2.1e-06 26.7 1.0 1.4 1 1 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 KXL44449.1 - 1.7e-06 27.6 3.9 0.024 13.9 1.8 2.5 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KXL44449.1 - 2.1e-06 27.2 3.7 1.7e-05 24.2 3.6 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXL44449.1 - 8.7e-06 26.2 1.1 0.0002 21.9 0.7 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXL44449.1 - 2.6e-05 23.8 2.3 4.1e-05 23.1 2.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXL44449.1 - 0.00049 19.3 7.4 0.00086 18.5 7.4 1.4 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 KXL44449.1 - 0.0013 17.6 5.0 0.0035 16.3 3.0 2.2 3 0 0 3 3 3 1 Tryptophan halogenase Rossmann-like PF10727.9 KXL44449.1 - 0.0031 17.4 0.5 0.0072 16.2 0.5 1.6 1 0 0 1 1 1 1 Rossmann-like domain AlaDh_PNT_C PF01262.21 KXL44449.1 - 0.011 15.0 2.9 0.03 13.6 2.9 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KXL44449.1 - 0.016 14.3 4.6 0.026 13.6 4.6 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KXL44449.1 - 0.034 13.4 5.8 0.19 11.0 5.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXL44449.1 - 0.038 13.2 0.4 0.064 12.5 0.4 1.3 1 0 0 1 1 1 0 Thi4 family UPF0146 PF03686.13 KXL44449.1 - 0.16 11.9 0.1 15 5.5 0.0 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0146) 3HCDH_N PF02737.18 KXL44449.1 - 0.77 9.6 2.7 1.3 8.8 2.7 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans PF04082.18 KXL44450.1 - 3.1e-32 111.7 0.4 5.9e-32 110.7 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL44450.1 - 7.9e-09 35.5 12.4 1.5e-08 34.6 12.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_1 PF00561.20 KXL44451.1 - 1.4e-16 60.9 0.0 7.2e-14 52.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXL44451.1 - 1.1e-08 34.6 0.0 6e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXL44451.1 - 4e-05 24.3 0.0 4.7e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 KXL44451.1 - 0.00027 19.7 0.0 0.00055 18.7 0.0 1.4 2 0 0 2 2 2 1 Ndr family Abhydrolase_2 PF02230.16 KXL44451.1 - 0.0051 16.6 0.0 0.027 14.3 0.1 2.0 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KXL44451.1 - 0.019 14.4 0.1 5.2 6.5 0.0 2.4 2 1 0 2 2 2 0 Prolyl oligopeptidase family AXE1 PF05448.12 KXL44451.1 - 0.03 13.0 0.1 0.26 9.9 0.0 2.3 3 0 0 3 3 3 0 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 KXL44451.1 - 0.084 12.8 0.0 0.77 9.6 0.0 2.0 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal PGAP1 PF07819.13 KXL44451.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein HECT PF00632.25 KXL44453.1 - 5e-94 315.2 0.7 2.7e-93 312.8 0.5 2.2 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 KXL44453.1 - 1.4e-19 68.8 35.2 1e-08 34.3 3.0 5.7 5 1 1 6 6 6 4 Ubiquitin binding region PV-1 PF06637.11 KXL44453.1 - 2 7.2 15.3 3.7 6.3 15.3 1.3 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Borrelia_P83 PF05262.11 KXL44453.1 - 2.4 6.5 18.9 1.9 6.9 15.9 2.0 2 0 0 2 2 2 0 Borrelia P83/100 protein Myotub-related PF06602.14 KXL44454.1 - 5.8e-130 433.3 0.0 7.1e-130 433.0 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain NeA_P2 PF12312.8 KXL44454.1 - 0.025 14.0 0.1 0.056 12.9 0.1 1.5 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein Y_phosphatase3 PF13350.6 KXL44454.1 - 0.025 14.5 0.0 0.068 13.1 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family Vps39_1 PF10366.9 KXL44455.1 - 2.4e-28 98.5 0.0 9.3e-28 96.7 0.0 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 KXL44455.1 - 1.9e-23 83.0 0.0 1.3e-22 80.3 0.0 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 KXL44455.1 - 7.1e-15 55.3 0.0 9.9e-14 51.6 0.0 2.3 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.20 KXL44455.1 - 1.1e-05 25.4 1.3 0.00032 20.6 0.8 2.4 2 0 0 2 2 2 1 Region in Clathrin and VPS TPR_1 PF00515.28 KXL44455.1 - 0.4 10.6 2.2 26 4.8 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXL44455.1 - 0.66 10.3 5.8 20 5.5 0.0 4.4 3 2 1 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KXL44455.1 - 5.7 7.2 5.2 23 5.3 0.0 4.1 4 2 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 LSM PF01423.22 KXL44456.1 - 5.7e-15 54.8 0.0 8.5e-15 54.2 0.0 1.3 1 0 0 1 1 1 1 LSM domain AT_hook PF02178.19 KXL44457.1 - 0.028 14.3 5.1 0.12 12.3 5.1 2.2 1 0 0 1 1 1 0 AT hook motif IAT_beta PF11924.8 KXL44458.1 - 0.013 14.9 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Inverse autotransporter, beta-domain zf-MYND PF01753.18 KXL44459.1 - 7.8e-06 25.9 10.2 0.0044 17.1 0.8 2.4 2 0 0 2 2 2 2 MYND finger ParBc_2 PF08857.11 KXL44459.1 - 0.088 12.9 0.1 0.23 11.5 0.1 1.6 2 0 0 2 2 2 0 Putative ParB-like nuclease ACAS_N PF16177.5 KXL44459.1 - 0.1 12.5 5.3 0.14 12.1 3.6 2.1 2 0 0 2 2 2 0 Acetyl-coenzyme A synthetase N-terminus DinB PF05163.12 KXL44459.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 DinB family UIM PF02809.20 KXL44460.1 - 1.4e-05 24.7 0.6 3.1e-05 23.6 0.6 1.6 1 0 0 1 1 1 1 Ubiquitin interaction motif DUF913 PF06025.12 KXL44462.1 - 8.6e-111 370.5 0.0 6.5e-109 364.3 0.0 2.3 1 1 0 1 1 1 1 Domain of Unknown Function (DUF913) DUF908 PF06012.12 KXL44462.1 - 2.8e-96 323.0 3.1 4.5e-96 322.4 3.1 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) DDE_1 PF03184.19 KXL44463.1 - 2.1e-22 79.6 0.0 2.9e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Acetyltransf_4 PF13420.7 KXL44464.1 - 1e-06 29.0 0.0 1.2e-06 28.8 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KXL44464.1 - 1.3e-05 25.9 0.0 1.6e-05 25.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXL44464.1 - 3.7e-05 23.9 0.1 4.8e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXL44464.1 - 0.0004 20.3 0.0 0.00047 20.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXL44464.1 - 0.0012 19.2 0.0 0.0016 18.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KXL44464.1 - 0.067 12.9 0.0 0.08 12.6 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SLT PF01464.20 KXL44466.1 - 0.029 14.0 0.0 0.064 12.9 0.0 1.5 2 0 0 2 2 2 0 Transglycosylase SLT domain Lysozyme_like PF13702.6 KXL44466.1 - 0.05 13.3 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 Lysozyme-like DUF1989 PF09347.10 KXL44467.1 - 2.7e-41 141.0 0.0 3.3e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) DUF2183 PF09949.9 KXL44468.1 - 3.7e-32 110.6 0.0 9e-32 109.4 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) UIM PF02809.20 KXL44468.1 - 0.047 13.6 5.2 0.13 12.2 5.2 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif LNS2 PF08235.13 KXL44468.1 - 0.18 11.3 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) Herpes_LAMP2 PF06126.11 KXL44468.1 - 0.26 9.8 0.2 0.4 9.2 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 Sugar_tr PF00083.24 KXL44469.1 - 2.7e-123 412.2 23.0 3.1e-123 412.0 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL44469.1 - 9.7e-24 83.9 58.2 3.1e-21 75.7 28.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2107 PF09880.9 KXL44469.1 - 0.013 15.6 0.5 11 6.2 0.0 3.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2107) ArAE_1 PF06081.11 KXL44469.1 - 0.051 13.7 13.9 0.11 12.6 0.8 3.1 3 1 0 3 3 3 0 Aromatic acid exporter family member 1 Cas_Cas2CT1978 PF09707.10 KXL44469.1 - 0.077 13.1 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas2CT1978) DUF4064 PF13273.6 KXL44469.1 - 1.2 9.4 25.7 0.37 11.1 6.2 5.1 4 1 1 5 5 5 0 Protein of unknown function (DUF4064) NUC173 PF08161.12 KXL44470.1 - 1.1e-77 260.4 0.1 6.9e-74 247.9 0.0 3.2 2 0 0 2 2 2 2 NUC173 domain HEAT_2 PF13646.6 KXL44470.1 - 0.0096 16.3 0.4 1.1 9.7 0.2 4.1 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 KXL44470.1 - 0.043 14.1 3.3 9.1 6.9 0.1 4.2 5 0 0 5 5 5 0 HEAT repeat CdiI_2 PF18593.1 KXL44470.1 - 0.082 13.6 0.0 10 6.9 0.0 2.9 2 0 0 2 2 2 0 CdiI immunity protein DUF1674 PF07896.12 KXL44471.1 - 1.5e-19 70.2 2.6 1.5e-19 70.2 2.6 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1674) 4HBT PF03061.22 KXL44472.1 - 6.1e-12 45.7 0.1 9.1e-12 45.2 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KXL44472.1 - 0.0054 17.0 0.0 0.008 16.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily HAUS4 PF14735.6 KXL44473.1 - 1.8e-09 37.7 10.7 1.8e-09 37.7 10.7 1.4 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 4 Phage_GP20 PF06810.11 KXL44473.1 - 0.026 14.3 1.9 0.026 14.3 1.9 2.8 2 1 1 3 3 3 0 Phage minor structural protein GP20 NID PF07292.13 KXL44473.1 - 0.25 12.0 2.1 12 6.6 0.0 3.3 3 0 0 3 3 3 0 Nmi/IFP 35 domain (NID) DUF5082 PF16888.5 KXL44473.1 - 0.49 10.7 16.0 3.3 8.0 1.1 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) TSC22 PF01166.18 KXL44473.1 - 0.66 10.3 0.1 0.66 10.3 0.1 4.5 5 0 0 5 5 5 0 TSC-22/dip/bun family Prefoldin_2 PF01920.20 KXL44473.1 - 1 9.3 19.5 0.43 10.5 5.1 3.8 3 1 1 4 4 4 0 Prefoldin subunit Ntox28 PF15605.6 KXL44473.1 - 1.3 9.3 6.1 32 4.8 0.1 3.4 3 0 0 3 3 3 0 Bacterial toxin 28 TMF_DNA_bd PF12329.8 KXL44473.1 - 1.3 9.1 19.1 0.86 9.6 1.3 4.4 5 0 0 5 5 5 0 TATA element modulatory factor 1 DNA binding DUF4201 PF13870.6 KXL44473.1 - 1.4 8.6 16.0 0.7 9.6 8.0 2.9 2 1 0 3 3 3 0 Domain of unknown function (DUF4201) LapA_dom PF06305.11 KXL44473.1 - 5 7.0 6.1 27 4.7 1.2 3.2 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain HAUS6_N PF14661.6 KXL44473.1 - 5.8 6.4 10.3 6.6 6.2 7.5 2.2 1 1 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus COG2 PF06148.11 KXL44473.1 - 9.4 6.3 11.8 11 6.2 3.4 3.7 2 2 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 RIBIOP_C PF04950.12 KXL44474.1 - 1.9e-109 365.6 0.0 2.7e-109 365.1 0.0 1.3 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KXL44474.1 - 6e-15 55.1 0.3 1e-13 51.2 0.1 2.9 2 1 0 2 2 2 1 AARP2CN (NUC121) domain SIMPL PF04402.14 KXL44475.1 - 4.6e-18 66.4 0.0 5.6e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) RabGAP-TBC PF00566.18 KXL44476.1 - 5.1e-47 160.3 7.3 6.2e-47 160.0 0.1 3.1 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Cnn_1N PF07989.11 KXL44476.1 - 0.00028 21.0 8.7 0.00028 21.0 8.7 3.3 2 1 1 3 3 2 2 Centrosomin N-terminal motif 1 APG6_N PF17675.1 KXL44476.1 - 0.0053 17.3 15.2 0.0053 17.3 15.2 3.1 3 1 0 4 4 4 1 Apg6 coiled-coil region YabA PF06156.13 KXL44476.1 - 0.015 15.9 19.2 0.034 14.8 3.7 3.2 1 1 1 2 2 2 0 Initiation control protein YabA Mt_ATP-synt_D PF05873.12 KXL44476.1 - 0.06 13.2 10.7 0.3 10.9 8.8 2.5 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Seadorna_VP6 PF07407.11 KXL44476.1 - 0.071 12.0 8.2 0.18 10.7 8.1 1.6 1 1 0 1 1 1 0 Seadornavirus VP6 protein DUF4201 PF13870.6 KXL44476.1 - 0.15 11.7 23.5 0.63 9.7 23.5 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF2621 PF11084.8 KXL44476.1 - 0.17 11.8 0.5 0.36 10.8 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) KASH_CCD PF14662.6 KXL44476.1 - 0.24 11.2 27.5 0.25 11.2 15.6 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH T3SSipB PF16535.5 KXL44476.1 - 0.38 11.2 17.5 0.16 12.4 5.7 2.4 1 1 1 2 2 2 0 Type III cell invasion protein SipB TSC22 PF01166.18 KXL44476.1 - 1.4 9.2 19.8 7.4 7.0 5.2 3.7 2 1 1 3 3 3 0 TSC-22/dip/bun family Atg14 PF10186.9 KXL44476.1 - 2.9 6.9 20.7 0.4 9.7 16.4 1.7 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 HALZ PF02183.18 KXL44476.1 - 4 7.7 27.5 0.059 13.6 3.3 4.9 5 0 0 5 5 5 0 Homeobox associated leucine zipper COG2 PF06148.11 KXL44476.1 - 6.8 6.8 14.4 16 5.6 12.7 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 bZIP_1 PF00170.21 KXL44476.1 - 7.5 6.7 25.3 1.8 8.7 2.6 4.0 2 1 1 3 3 3 0 bZIP transcription factor Dynactin PF12455.8 KXL44478.1 - 2e-100 335.7 15.2 2e-100 335.7 15.2 3.6 3 1 0 3 3 3 1 Dynein associated protein CAP_GLY PF01302.25 KXL44478.1 - 2.8e-24 84.9 0.4 4.8e-24 84.1 0.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain BRI3BP PF14965.6 KXL44478.1 - 8.2 5.9 7.0 26 4.3 0.6 3.4 3 0 0 3 3 3 0 Negative regulator of p53/TP53 SPO22 PF08631.10 KXL44479.1 - 7.5e-35 120.7 0.1 7.5e-35 120.7 0.1 3.3 5 0 0 5 5 5 1 Meiosis protein SPO22/ZIP4 like Peptidase_C33 PF05412.12 KXL44479.1 - 0.83 9.7 3.0 4.6 7.3 0.2 3.1 2 1 1 3 3 3 0 Equine arterivirus Nsp2-type cysteine proteinase DUF4233 PF14017.6 KXL44480.1 - 1.4 9.3 8.9 2.9 8.3 8.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4233) FMO-like PF00743.19 KXL44482.1 - 2.7e-10 39.3 0.1 9.2e-10 37.6 0.0 1.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXL44482.1 - 1.1e-09 38.4 0.0 3.5e-09 36.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXL44482.1 - 1.7e-06 27.5 0.0 3.6e-05 23.1 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KXL44482.1 - 2.1e-05 23.9 0.0 0.0011 18.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXL44482.1 - 0.00015 21.4 0.2 0.15 11.6 0.0 2.7 2 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXL44482.1 - 0.00049 19.4 0.0 0.0028 17.0 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXL44482.1 - 0.00079 19.4 0.2 0.029 14.4 0.0 3.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 KXL44482.1 - 0.042 13.1 0.0 0.23 10.7 0.0 1.9 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 KXL44482.1 - 0.064 11.9 0.1 0.098 11.3 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Ycf34 PF10718.9 KXL44482.1 - 0.079 13.7 0.7 12 6.7 0.4 2.9 2 0 0 2 2 2 0 Hypothetical chloroplast protein Ycf34 DUF1751 PF08551.10 KXL44483.1 - 2.2e-25 89.1 1.0 5.5e-25 87.8 1.0 1.7 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 KXL44483.1 - 3e-06 27.3 5.4 4.9e-06 26.6 5.4 1.3 1 0 0 1 1 1 1 Rhomboid family CPBP PF02517.16 KXL44483.1 - 8.6 6.8 9.0 37 4.8 7.7 2.6 2 1 0 2 2 2 0 CPBP intramembrane metalloprotease LisH PF08513.11 KXL44484.1 - 4.9e-05 23.1 0.2 0.00013 21.8 0.2 1.7 1 0 0 1 1 1 1 LisH ANAPC4_WD40 PF12894.7 KXL44484.1 - 0.00041 20.6 0.1 0.57 10.5 0.0 4.8 5 2 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KXL44484.1 - 0.00041 20.2 2.1 0.45 10.5 0.0 3.4 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat WD40 PF00400.32 KXL44484.1 - 0.003 18.4 4.7 9.5 7.3 0.1 5.8 6 0 0 6 6 6 1 WD domain, G-beta repeat FhuF_C PF11575.8 KXL44484.1 - 0.046 13.7 1.0 0.13 12.3 0.2 2.2 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain HTH_psq PF05225.16 KXL44485.1 - 0.0009 18.9 1.7 0.0011 18.6 1.7 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DUF4250 PF14056.6 KXL44485.1 - 0.18 11.8 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) Velvet PF11754.8 KXL44486.1 - 3.8e-49 167.9 0.0 3.1e-33 115.8 0.0 4.0 2 2 1 3 3 3 2 Velvet factor GST_N_2 PF13409.6 KXL44487.1 - 4.7e-10 39.6 0.0 7.9e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXL44487.1 - 5e-10 39.6 0.0 8.7e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXL44487.1 - 0.0043 17.0 0.3 0.012 15.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain FMN_red PF03358.15 KXL44488.1 - 6.6e-25 87.7 0.0 1.1e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KXL44488.1 - 0.046 13.4 0.0 0.088 12.5 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin-like fold zf-P11 PF03854.14 KXL44490.1 - 0.13 11.9 1.8 0.25 11.0 1.8 1.6 1 1 0 1 1 1 0 P-11 zinc finger TPT PF03151.16 KXL44491.1 - 2.3e-10 40.3 3.4 4.8e-10 39.3 3.4 1.5 1 1 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KXL44491.1 - 0.00018 20.8 2.8 0.00019 20.8 2.1 1.4 1 1 0 1 1 1 1 UAA transporter family UDPG_MGDP_dh_N PF03721.14 KXL44492.1 - 8.2e-36 123.3 0.0 3.3e-35 121.4 0.0 1.9 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 KXL44492.1 - 6.5e-24 84.0 0.0 1.2e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 KXL44492.1 - 4.8e-20 71.9 0.0 2.4e-19 69.7 0.1 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain TPT PF03151.16 KXL44493.1 - 3.9e-35 121.6 19.4 4.5e-35 121.4 19.4 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KXL44493.1 - 2e-16 60.1 23.6 2.4e-16 59.8 23.6 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KXL44493.1 - 3.8e-07 30.3 32.3 8.1e-05 22.8 16.9 2.2 2 0 0 2 2 2 2 EamA-like transporter family NAD_binding_1 PF00175.21 KXL44494.1 - 3.3e-23 82.4 0.0 5.9e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KXL44494.1 - 2.4e-17 63.1 0.0 3.9e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KXL44494.1 - 1.7e-09 38.0 0.0 6.1e-08 32.9 0.0 2.2 1 1 1 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KXL44494.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain QRPTase_C PF01729.19 KXL44496.1 - 9.6e-54 181.7 0.0 1.2e-53 181.4 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KXL44496.1 - 1e-21 76.8 0.0 2.9e-21 75.3 0.0 1.8 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain B12-binding PF02310.19 KXL44496.1 - 0.02 14.9 0.1 0.13 12.3 0.1 2.3 2 0 0 2 2 2 0 B12 binding domain ADH_zinc_N PF00107.26 KXL44496.1 - 0.074 13.0 0.9 0.32 11.0 0.5 2.0 2 0 0 2 2 2 0 Zinc-binding dehydrogenase PTS_IIB PF02302.17 KXL44496.1 - 0.11 13.3 1.7 0.22 12.2 1.4 1.7 1 1 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIB subunit IGPS PF00218.21 KXL44496.1 - 0.14 11.3 0.0 0.37 9.9 0.0 1.6 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase Shisa PF13908.6 KXL44498.1 - 2.4e-05 24.7 0.9 3.9e-05 24.0 0.9 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator TMEM154 PF15102.6 KXL44498.1 - 0.00015 21.7 0.0 0.00023 21.1 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 KXL44498.1 - 0.0012 19.7 2.4 0.0025 18.6 2.4 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM156 PF15106.6 KXL44498.1 - 0.0021 17.5 0.4 0.0031 17.0 0.4 1.3 1 0 0 1 1 1 1 TMEM156 protein family Baculo_F PF12259.8 KXL44498.1 - 0.0032 16.1 0.1 0.0038 15.8 0.1 1.1 1 0 0 1 1 1 1 Baculovirus F protein ECSCR PF15820.5 KXL44498.1 - 0.0033 17.2 3.5 0.0067 16.2 3.5 1.5 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator DUF4834 PF16118.5 KXL44498.1 - 0.0047 17.9 1.4 0.01 16.8 1.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) Tmemb_9 PF05434.11 KXL44498.1 - 0.0062 16.4 0.3 0.0075 16.2 0.3 1.2 1 0 0 1 1 1 1 TMEM9 Orf78 PF06024.12 KXL44498.1 - 0.0078 16.5 0.3 0.012 15.9 0.3 1.3 1 0 0 1 1 1 1 Orf78 (ac78) WBP-1 PF11669.8 KXL44498.1 - 0.012 16.2 1.1 0.028 15.0 1.1 1.7 1 0 0 1 1 1 0 WW domain-binding protein 1 LRR19-TM PF15176.6 KXL44498.1 - 0.025 14.5 3.2 0.05 13.6 3.2 1.4 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain AJAP1_PANP_C PF15298.6 KXL44498.1 - 0.04 14.1 0.0 0.073 13.3 0.0 1.5 1 0 0 1 1 1 0 AJAP1/PANP C-terminus TRP PF06011.12 KXL44498.1 - 0.059 12.1 1.4 0.079 11.7 1.4 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel LRRC37AB_C PF14914.6 KXL44498.1 - 0.09 12.7 0.6 0.12 12.3 0.6 1.2 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Protocadherin PF08374.11 KXL44498.1 - 0.11 12.5 1.6 0.17 11.8 1.6 1.3 1 0 0 1 1 1 0 Protocadherin Binary_toxB PF03495.14 KXL44498.1 - 0.12 12.6 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA Ca-binding domain SP_C-Propep PF08999.10 KXL44498.1 - 0.12 12.2 7.6 0.22 11.3 7.6 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide PRIMA1 PF16101.5 KXL44498.1 - 0.13 12.3 5.0 0.24 11.4 5.0 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DAG1 PF05454.11 KXL44498.1 - 0.14 11.5 3.4 0.19 11.0 3.4 1.1 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) TMEM52 PF14979.6 KXL44498.1 - 0.14 12.0 1.7 0.24 11.3 1.7 1.4 1 0 0 1 1 1 0 Transmembrane 52 TMEM108 PF15759.5 KXL44498.1 - 0.16 11.0 2.1 0.2 10.6 2.1 1.1 1 0 0 1 1 1 0 TMEM108 family MAP17 PF15807.5 KXL44498.1 - 0.18 12.0 2.8 0.29 11.4 2.8 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF929 PF06053.11 KXL44498.1 - 0.19 11.0 2.7 0.63 9.3 3.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF929) RCR PF12273.8 KXL44498.1 - 0.22 12.2 4.9 0.11 13.1 2.2 1.9 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Stevor PF17410.2 KXL44498.1 - 0.37 10.3 1.2 0.56 9.7 1.2 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame HemY_N PF07219.13 KXL44498.1 - 0.37 11.0 3.1 0.26 11.5 0.9 1.7 2 0 0 2 2 1 0 HemY protein N-terminus Comm PF15957.5 KXL44498.1 - 0.86 10.0 7.2 0.37 11.1 4.5 1.7 2 0 0 2 2 2 0 Commissureless Baculo_11_kDa PF06143.11 KXL44498.1 - 0.94 9.1 9.8 1.7 8.3 9.8 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family Cadherin_C_2 PF16492.5 KXL44498.1 - 1.9 9.3 4.2 0.94 10.3 2.1 1.6 2 0 0 2 2 1 0 Cadherin cytoplasmic C-terminal Vpu PF00558.19 KXL44498.1 - 2.3 8.1 4.7 4.8 7.0 4.7 1.5 1 0 0 1 1 1 0 Vpu protein TMEM132D_C PF15706.5 KXL44498.1 - 3.3 7.6 6.5 0.58 10.0 2.9 1.7 2 0 0 2 2 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF515 PF04415.12 KXL44498.1 - 4.5 5.6 6.7 6.8 5.0 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) RRN3 PF05327.11 KXL44499.1 - 0.015 13.8 1.4 0.025 13.1 1.4 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 KXL44499.1 - 5.6 5.1 11.6 8.4 4.6 11.6 1.1 1 0 0 1 1 1 0 CDC45-like protein AAA PF00004.29 KXL44500.1 - 2.1e-42 144.6 0.0 4.2e-42 143.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KXL44500.1 - 3.8e-30 103.7 0.1 1.2e-29 102.0 0.1 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 KXL44500.1 - 2.3e-23 82.0 6.2 5.5e-23 80.8 6.2 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 KXL44500.1 - 2.8e-06 27.0 0.0 1.4e-05 24.8 0.0 2.2 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KXL44500.1 - 5.4e-06 26.2 0.0 1.2e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXL44500.1 - 8.4e-06 26.3 0.1 0.0015 19.0 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 KXL44500.1 - 4.8e-05 23.2 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 KXL44500.1 - 5.3e-05 23.2 0.0 0.00024 21.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KXL44500.1 - 5.3e-05 23.6 0.0 0.012 16.0 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_2 PF07724.14 KXL44500.1 - 7.3e-05 22.9 0.0 0.0061 16.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 KXL44500.1 - 8.6e-05 21.9 0.0 0.00015 21.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KXL44500.1 - 0.00012 22.3 0.1 0.0066 16.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KXL44500.1 - 0.00017 21.6 0.0 0.00046 20.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KXL44500.1 - 0.00031 20.0 0.0 0.002 17.3 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KXL44500.1 - 0.00077 20.0 0.3 0.0028 18.2 0.0 2.1 2 1 0 2 2 1 1 AAA domain USP8_dimer PF08969.11 KXL44500.1 - 0.001 19.2 4.4 0.0021 18.2 4.4 1.6 1 0 0 1 1 1 1 USP8 dimerisation domain AAA_24 PF13479.6 KXL44500.1 - 0.0014 18.4 0.1 0.0052 16.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXL44500.1 - 0.0019 18.3 0.0 0.0058 16.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KXL44500.1 - 0.017 15.6 0.2 0.06 13.8 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 KXL44500.1 - 0.017 14.6 0.0 0.12 11.9 0.0 2.3 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 KXL44500.1 - 0.023 14.3 0.0 0.61 9.6 0.1 2.5 1 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KXL44500.1 - 0.024 14.0 0.0 0.081 12.3 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Torsin PF06309.11 KXL44500.1 - 0.04 14.0 0.0 0.09 12.9 0.0 1.5 1 0 0 1 1 1 0 Torsin TPR_1 PF00515.28 KXL44500.1 - 0.041 13.7 2.9 0.19 11.6 3.0 2.2 1 1 0 1 1 1 0 Tetratricopeptide repeat Parvo_NS1 PF01057.17 KXL44500.1 - 0.057 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Phage_GPO PF05929.11 KXL44500.1 - 0.064 12.9 0.8 0.11 12.1 0.8 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase NACHT PF05729.12 KXL44500.1 - 0.076 12.9 0.0 0.69 9.8 0.0 2.1 1 1 1 2 2 2 0 NACHT domain PhoH PF02562.16 KXL44500.1 - 0.078 12.4 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein Zeta_toxin PF06414.12 KXL44500.1 - 0.098 11.9 0.1 1.5 8.0 0.1 2.6 2 1 1 3 3 3 0 Zeta toxin AAA_21 PF13304.6 KXL44500.1 - 0.11 12.3 0.2 13 5.4 0.1 2.4 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Sigma54_activat PF00158.26 KXL44500.1 - 0.15 11.7 0.0 0.49 10.1 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Use1 PF09753.9 KXL44500.1 - 0.15 11.7 2.5 0.32 10.7 2.5 1.4 1 0 0 1 1 1 0 Membrane fusion protein Use1 AFG1_ATPase PF03969.16 KXL44500.1 - 0.17 10.8 0.0 0.39 9.5 0.0 1.6 1 0 0 1 1 1 0 AFG1-like ATPase Cytidylate_kin PF02224.18 KXL44500.1 - 0.19 11.4 1.1 0.5 10.1 0.0 2.2 2 1 1 3 3 3 0 Cytidylate kinase ATPase_2 PF01637.18 KXL44500.1 - 0.24 11.3 2.4 1.2 9.0 0.0 2.7 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Prefoldin_2 PF01920.20 KXL44501.1 - 3.5e-23 81.6 8.4 4.4e-23 81.2 8.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.6 KXL44501.1 - 0.00039 20.4 3.6 0.00058 19.9 3.6 1.2 1 0 0 1 1 1 1 Prefoldin subunit Spc24 PF08286.11 KXL44501.1 - 0.0023 18.2 10.2 0.02 15.1 1.7 2.1 1 1 1 2 2 2 2 Spc24 subunit of Ndc80 MIP-T3_C PF17749.1 KXL44501.1 - 0.0048 16.9 3.3 0.0048 16.9 3.3 1.9 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 C-terminal region Prefoldin PF02996.17 KXL44501.1 - 0.0077 16.1 7.9 0.017 15.1 7.9 1.6 1 1 0 1 1 1 1 Prefoldin subunit PHM7_cyt PF14703.6 KXL44501.1 - 0.025 14.8 3.8 0.049 13.9 3.8 1.6 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter ATG16 PF08614.11 KXL44501.1 - 0.058 13.6 1.4 0.058 13.6 1.4 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Jnk-SapK_ap_N PF09744.9 KXL44501.1 - 0.059 13.6 5.3 0.076 13.2 5.3 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF5082 PF16888.5 KXL44501.1 - 0.067 13.5 11.4 3.5 7.9 11.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Sec16 PF12932.7 KXL44501.1 - 0.095 13.3 0.5 0.11 13.0 0.5 1.2 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region Rx_N PF18052.1 KXL44501.1 - 0.21 11.9 3.0 7 7.0 0.1 2.1 2 0 0 2 2 2 0 Rx N-terminal domain CENP-F_leu_zip PF10473.9 KXL44501.1 - 0.22 11.5 10.5 0.39 10.7 1.8 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.10 KXL44501.1 - 0.34 11.1 7.5 0.48 10.6 7.5 1.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Uso1_p115_C PF04871.13 KXL44501.1 - 0.55 10.6 9.4 33 4.9 9.3 2.1 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Spc7 PF08317.11 KXL44501.1 - 0.64 8.8 10.3 1.2 8.0 10.3 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein UPF0242 PF06785.11 KXL44501.1 - 1.2 9.2 10.5 2.5 8.2 10.5 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 KXL44501.1 - 1.5 9.3 10.1 65 4.1 10.1 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region FlaC_arch PF05377.11 KXL44501.1 - 1.8 9.0 7.8 2.2 8.8 0.4 2.9 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) ABC_tran_CTD PF16326.5 KXL44501.1 - 2.6 8.4 7.1 4.2 7.7 0.5 3.0 2 1 0 2 2 2 0 ABC transporter C-terminal domain TMPIT PF07851.13 KXL44501.1 - 3.2 6.9 5.2 1.3 8.2 2.4 1.5 1 1 0 1 1 1 0 TMPIT-like protein Osmo_CC PF08946.10 KXL44501.1 - 3.2 8.1 8.0 0.37 11.1 2.6 2.3 2 2 0 2 2 2 0 Osmosensory transporter coiled coil YabA PF06156.13 KXL44501.1 - 3.4 8.3 6.4 8.5 7.1 0.5 2.1 2 0 0 2 2 2 0 Initiation control protein YabA Siah-Interact_N PF09032.11 KXL44501.1 - 6.7 7.1 11.6 5.2 7.5 1.8 2.5 3 0 0 3 3 2 0 Siah interacting protein, N terminal SMC_N PF02463.19 KXL44502.1 - 1.5e-69 233.8 27.9 5e-69 232.1 27.9 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KXL44502.1 - 1.4e-26 93.1 0.0 5.4e-26 91.2 0.0 2.1 2 0 0 2 2 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KXL44502.1 - 5.3e-10 40.1 0.1 5.3e-10 40.1 0.1 6.6 2 2 4 6 6 2 1 AAA domain AAA_21 PF13304.6 KXL44502.1 - 4.3e-09 36.6 10.8 2.7e-05 24.1 0.1 3.4 3 2 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KXL44502.1 - 3.5e-08 33.5 3.1 3.5e-08 33.5 3.1 4.5 2 2 2 4 4 3 1 AAA ATPase domain Myosin_tail_1 PF01576.19 KXL44502.1 - 1.4e-06 26.5 49.2 1.4e-06 26.5 49.2 4.2 3 1 2 5 5 5 1 Myosin tail AAA_29 PF13555.6 KXL44502.1 - 0.00066 19.4 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ERM PF00769.19 KXL44502.1 - 0.0025 17.7 18.8 0.0025 17.7 18.8 5.4 3 2 2 5 5 5 2 Ezrin/radixin/moesin family DUF5082 PF16888.5 KXL44502.1 - 0.0088 16.3 8.5 0.0088 16.3 8.5 8.4 4 2 4 9 9 8 2 Domain of unknown function (DUF5082) SbcCD_C PF13558.6 KXL44502.1 - 0.073 13.3 0.0 1.5 9.1 0.0 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Hemocyanin_C PF03723.14 KXL44502.1 - 0.17 11.2 1.2 0.3 10.4 0.4 1.8 1 1 1 2 2 2 0 Hemocyanin, ig-like domain Shugoshin_N PF07558.11 KXL44502.1 - 2.3 8.2 8.2 7.4 6.5 1.6 3.2 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Acetyltransf_11 PF13720.6 KXL44502.1 - 2.5 8.6 6.5 3.7 8.1 0.9 4.0 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 SPT_ssu-like PF11779.8 KXL44503.1 - 4.2e-13 48.7 2.1 7.8e-13 47.8 2.1 1.4 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like Prenylcys_lyase PF07156.14 KXL44504.1 - 5.9e-89 298.7 0.0 8.4e-89 298.2 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 KXL44504.1 - 9.2e-13 48.2 0.1 1.9e-12 47.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KXL44504.1 - 1e-09 38.2 0.0 2.4e-09 37.0 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 KXL44504.1 - 8.8e-08 32.1 0.3 2e-06 27.6 0.5 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXL44504.1 - 2.7e-06 27.4 0.0 0.00019 21.5 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KXL44504.1 - 0.0029 16.9 0.0 0.0048 16.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXL44504.1 - 0.0063 15.9 0.7 1.7 7.9 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 KXL44504.1 - 0.0069 15.6 0.4 0.1 11.8 0.2 2.1 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 KXL44504.1 - 0.025 13.8 0.0 4.2 6.4 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 KXL44504.1 - 0.14 11.4 0.1 0.21 10.8 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 KXL44504.1 - 0.16 11.6 0.3 0.39 10.4 0.3 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 KXL44504.1 - 0.18 12.3 0.1 0.74 10.4 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Gag_MA PF01140.19 KXL44504.1 - 0.19 11.5 0.1 0.39 10.5 0.1 1.4 1 0 0 1 1 1 0 Matrix protein (MA), p15 Sec7 PF01369.20 KXL44505.1 - 3.1e-28 98.7 0.0 6e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 KXL44505.1 - 1.4e-17 64.2 0.0 2.7e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Importin_rep_4 PF18808.1 KXL44506.1 - 5.7e-32 109.9 1.7 4e-31 107.2 0.4 3.3 1 1 1 2 2 2 1 Importin repeat Importin_rep_5 PF18816.1 KXL44506.1 - 2.2e-24 85.5 0.2 2.7e-23 82.0 0.3 2.7 2 0 0 2 2 2 1 Importin repeat HEAT_EZ PF13513.6 KXL44506.1 - 3e-24 85.1 12.4 8e-11 42.2 0.2 9.5 8 1 1 9 9 9 3 HEAT-like repeat HEAT_2 PF13646.6 KXL44506.1 - 9.2e-16 58.0 12.3 6.7e-06 26.4 0.0 8.2 5 3 2 8 8 8 3 HEAT repeats HEAT PF02985.22 KXL44506.1 - 3.2e-15 54.9 9.4 0.0049 17.0 0.0 10.5 11 0 0 11 11 9 2 HEAT repeat RIX1 PF08167.12 KXL44506.1 - 3.5e-12 46.5 0.0 0.0013 18.5 0.0 4.7 3 1 1 4 4 4 4 rRNA processing/ribosome biogenesis Importin_rep_6 PF18829.1 KXL44506.1 - 2.1e-11 43.9 1.3 2.1e-11 43.9 1.3 3.9 6 0 0 6 6 4 1 Importin repeat 6 Vac14_Fab1_bd PF12755.7 KXL44506.1 - 7.7e-09 36.0 0.0 0.0071 16.9 0.0 5.4 5 1 1 6 6 4 2 Vacuolar 14 Fab1-binding region Arm PF00514.23 KXL44506.1 - 2.5e-07 30.5 5.3 0.012 15.6 0.1 4.7 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 KXL44506.1 - 2e-06 27.9 0.6 0.24 11.4 0.0 5.3 3 3 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KXL44506.1 - 1.4e-05 24.8 2.0 0.0089 15.6 0.1 4.8 3 2 3 6 6 6 1 CLASP N terminal MMS19_C PF12460.8 KXL44506.1 - 3.2e-05 23.2 5.4 0.00048 19.3 0.2 4.0 3 1 0 3 3 3 1 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 KXL44506.1 - 4.5e-05 23.4 4.7 1.1 9.1 0.1 5.7 4 2 1 6 6 5 1 Domain of unknown function (DUF3385) DUF4042 PF13251.6 KXL44506.1 - 9.1e-05 22.2 0.3 7.7 6.2 0.0 5.1 4 0 0 4 4 4 1 Domain of unknown function (DUF4042) IBN_N PF03810.19 KXL44506.1 - 0.0003 20.6 0.4 0.012 15.5 0.0 3.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain DRIM PF07539.12 KXL44506.1 - 0.00035 19.0 9.1 0.0004 18.8 0.1 4.1 3 2 1 5 5 5 1 Down-regulated in metastasis DNA_alkylation PF08713.11 KXL44506.1 - 0.012 15.3 0.0 0.059 13.1 0.0 2.2 2 0 0 2 2 2 0 DNA alkylation repair enzyme RTP1_C1 PF10363.9 KXL44506.1 - 0.025 14.8 0.9 1.7 8.8 0.1 4.0 3 1 2 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 KXL44506.1 - 0.049 12.2 3.0 0.24 9.9 0.0 3.1 3 1 0 3 3 3 0 Adaptin N terminal region Dopey_N PF04118.14 KXL44506.1 - 0.078 12.1 3.3 1.2 8.2 0.0 3.4 4 0 0 4 4 4 0 Dopey, N-terminal Picorna_P3A PF06363.11 KXL44506.1 - 0.089 12.7 0.0 6.1 6.8 0.1 2.7 2 0 0 2 2 2 0 Picornaviridae P3A protein MMS19_N PF14500.6 KXL44506.1 - 2.3 7.7 7.6 11 5.5 0.0 4.3 5 0 0 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II Bromodomain PF00439.25 KXL44507.1 - 1.2e-17 63.7 0.4 1.2e-17 63.7 0.4 2.1 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.13 KXL44507.1 - 5.9e-08 32.6 0.0 2.1e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 Bromodomain associated SPARC_Ca_bdg PF10591.9 KXL44507.1 - 0.043 14.1 1.9 0.18 12.2 1.9 2.0 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region VanZ PF04892.12 KXL44508.1 - 2.4e-07 31.4 1.0 3.6e-07 30.9 1.0 1.2 1 0 0 1 1 1 1 VanZ like family Phage_holin_2_4 PF16082.5 KXL44508.1 - 0.11 12.2 0.1 0.27 11.0 0.1 1.6 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like TFIIA PF03153.13 KXL44508.1 - 0.18 11.8 5.6 0.2 11.6 5.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_S26e PF01283.19 KXL44509.1 - 6.4e-52 174.5 8.5 1.1e-51 173.8 8.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 KXL44509.1 - 0.042 13.8 0.4 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Zinc binding domain SF1-HH PF16275.5 KXL44509.1 - 0.06 13.7 0.0 0.073 13.4 0.0 1.3 1 0 0 1 1 1 0 Splicing factor 1 helix-hairpin domain DUF4668 PF15701.5 KXL44509.1 - 0.1 12.4 0.3 0.17 11.7 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) DUF1918 PF08940.11 KXL44509.1 - 0.16 11.6 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) CBS PF00571.28 KXL44510.1 - 5.1e-36 122.9 6.6 1.8e-09 37.9 0.0 6.0 5 1 0 5 5 5 4 CBS domain PB1 PF00564.24 KXL44510.1 - 2.3e-11 43.5 0.0 8.9e-11 41.6 0.0 2.1 2 0 0 2 2 2 1 PB1 domain U3_assoc_6 PF08640.11 KXL44511.1 - 8.2e-27 93.1 2.5 1.1e-25 89.5 0.2 2.3 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 KXL44511.1 - 0.00011 22.7 0.9 0.2 12.6 0.2 4.1 3 1 2 5 5 5 1 Tetratricopeptide repeat NRDE-2 PF08424.10 KXL44511.1 - 0.00099 18.3 1.1 0.0042 16.3 0.1 2.5 2 1 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_9 PF13371.6 KXL44511.1 - 0.012 15.8 0.1 0.1 12.7 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Suf PF05843.14 KXL44511.1 - 0.017 15.1 0.0 0.37 10.7 0.0 2.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Methyltransf_25 PF13649.6 KXL44512.1 - 4.9e-13 49.6 0.0 9.8e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL44512.1 - 2.7e-09 37.6 0.0 5.8e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL44512.1 - 8.7e-07 28.8 0.0 1.9e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXL44512.1 - 1.6e-05 24.8 0.1 5.4e-05 23.1 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL44512.1 - 0.00012 22.7 0.0 0.00031 21.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXL44512.1 - 0.0011 18.4 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 KXL44512.1 - 0.005 16.7 0.0 0.0088 15.9 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 KXL44512.1 - 0.061 12.9 0.0 0.34 10.5 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase small domain Complex1_LYR PF05347.15 KXL44513.1 - 4.5e-06 26.6 0.2 5.5e-06 26.3 0.2 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KXL44513.1 - 3.3e-05 24.5 0.2 3.8e-05 24.3 0.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Mito_carr PF00153.27 KXL44514.1 - 6.3e-68 224.8 4.2 1.5e-22 79.3 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.16 KXL44514.1 - 1.6 8.7 4.2 2.9 7.9 0.1 3.0 3 1 1 4 4 4 0 UcrQ family UCH PF00443.29 KXL44515.1 - 1.5e-32 113.1 0.0 4e-32 111.7 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 KXL44515.1 - 3.8e-32 110.0 4.2 4.2e-14 52.2 0.0 4.9 5 0 0 5 5 5 4 A repeated domain in UCH-protein UCH_1 PF13423.6 KXL44515.1 - 4.7e-06 26.4 0.2 0.00041 20.0 0.2 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Sipho_Gp157 PF05565.11 KXL44515.1 - 0.01 15.9 0.0 0.028 14.4 0.0 1.7 1 0 0 1 1 1 0 Siphovirus Gp157 HSCB_C PF07743.13 KXL44515.1 - 0.04 14.4 2.4 0.12 12.9 1.2 2.6 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain Tannase PF07519.11 KXL44517.1 - 1.3e-96 324.4 0.0 1.5e-96 324.2 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KXL44517.1 - 6.5e-05 22.3 0.0 0.014 14.7 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Esterase PF00756.20 KXL44517.1 - 0.02 14.6 0.1 0.033 13.8 0.1 1.3 1 0 0 1 1 1 0 Putative esterase DUF2647 PF10839.8 KXL44520.1 - 0.0079 16.2 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2647) NADH_dh_m_C1 PF15088.6 KXL44521.1 - 1.1 8.9 3.8 25 4.6 0.4 3.2 3 0 0 3 3 3 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial FMO-like PF00743.19 KXL44522.1 - 6.9e-38 130.4 0.0 9.3e-22 77.1 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXL44522.1 - 7.7e-14 51.6 0.5 6.7e-09 35.4 0.1 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXL44522.1 - 1.6e-10 40.8 0.0 5.9e-10 38.8 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXL44522.1 - 1.6e-07 31.5 0.0 3.3e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXL44522.1 - 5.2e-07 29.1 0.0 7.2e-05 22.1 0.0 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 KXL44522.1 - 2.9e-06 27.4 0.5 0.0001 22.3 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KXL44522.1 - 7.6e-06 25.3 0.8 0.00057 19.1 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KXL44522.1 - 1.1e-05 25.2 0.3 0.00078 19.1 0.4 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXL44522.1 - 0.0011 17.8 0.1 0.014 14.1 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KXL44522.1 - 0.0053 15.9 0.0 0.092 11.8 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 KXL44522.1 - 0.014 14.7 0.1 0.039 13.3 0.0 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KXL44522.1 - 0.021 15.4 0.2 0.64 10.6 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXL44522.1 - 0.023 14.0 0.0 0.042 13.1 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain MCRA PF06100.11 KXL44522.1 - 0.034 12.9 0.2 0.066 12.0 0.0 1.5 2 0 0 2 2 2 0 MCRA family Glu_dehyd_C PF16912.5 KXL44522.1 - 0.077 12.5 0.1 0.17 11.3 0.0 1.5 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Shikimate_DH PF01488.20 KXL44522.1 - 0.14 12.2 0.0 0.48 10.5 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DAP3 PF10236.9 KXL44523.1 - 1.2e-83 280.8 0.0 1.5e-83 280.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 Glyco_hydro_71 PF03659.14 KXL44524.1 - 3.9e-138 460.3 10.8 3.9e-138 460.3 10.8 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 71 Acetyltransf_1 PF00583.25 KXL44525.1 - 2.6e-06 27.7 0.0 9.9e-06 25.8 0.0 1.9 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXL44525.1 - 8.9e-06 25.7 0.0 1.6e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXL44525.1 - 0.001 19.4 0.0 0.0017 18.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXL44525.1 - 0.0078 16.3 0.0 0.65 10.1 0.0 2.8 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXL44525.1 - 0.077 13.0 0.1 0.27 11.2 0.1 1.8 1 1 0 1 1 1 0 FR47-like protein DUF1635 PF07795.11 KXL44526.1 - 0.23 11.3 1.4 0.44 10.4 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) zf-C2H2 PF00096.26 KXL44527.1 - 0.00014 22.1 3.9 0.058 13.9 0.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXL44527.1 - 0.0016 19.1 4.4 0.92 10.5 0.2 2.8 2 1 0 2 2 2 2 C2H2-type zinc finger zf-TFIIB PF13453.6 KXL44527.1 - 0.012 14.9 0.3 0.021 14.1 0.3 1.4 1 0 0 1 1 1 0 Transcription factor zinc-finger Zn-ribbon_8 PF09723.10 KXL44527.1 - 0.062 13.4 0.6 0.13 12.4 0.3 1.8 1 1 0 1 1 1 0 Zinc ribbon domain Zn_ribbon_recom PF13408.6 KXL44527.1 - 1.1 9.9 5.5 0.17 12.4 1.8 1.6 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain adh_short PF00106.25 KXL44529.1 - 3.7e-06 26.5 0.0 0.0014 18.1 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase Phage_connector PF05352.12 KXL44530.1 - 0.13 11.7 0.1 0.18 11.2 0.1 1.1 1 0 0 1 1 1 0 Phage Connector (GP10) DDE_3 PF13358.6 KXL44531.1 - 4.4e-07 29.7 0.3 6.4e-07 29.2 0.3 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Thioredoxin_2 PF13098.6 KXL44531.1 - 0.055 13.9 0.0 0.082 13.4 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain Syntaxin_2 PF14523.6 KXL44531.1 - 0.14 12.6 2.4 3.4 8.1 0.0 2.5 2 1 0 2 2 2 0 Syntaxin-like protein Isochorismatase PF00857.20 KXL44532.1 - 8e-28 97.8 0.0 1.1e-27 97.3 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family COX5B PF01215.19 KXL44533.1 - 1.5e-59 199.4 0.0 2.1e-59 198.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb A2L_zn_ribbon PF08792.10 KXL44533.1 - 0.062 13.0 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 A2L zinc ribbon domain Zn-ribbon_8 PF09723.10 KXL44533.1 - 0.11 12.6 0.9 0.32 11.1 0.9 1.8 1 1 0 1 1 1 0 Zinc ribbon domain Fungal_trans PF04082.18 KXL44534.1 - 1.5e-21 76.7 0.7 3.4e-21 75.5 0.7 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL44534.1 - 4.2e-08 33.2 9.8 8.2e-08 32.3 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1229 PF06797.11 KXL44534.1 - 0.0028 17.9 1.5 0.007 16.6 1.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1229) CGI-121 PF08617.10 KXL44535.1 - 1.4e-46 158.6 0.1 1.6e-46 158.4 0.1 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Methyltransf_2 PF00891.18 KXL44538.1 - 8.8e-26 90.5 0.0 1.5e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain BTB PF00651.31 KXL44541.1 - 0.00036 20.8 0.0 0.00061 20.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF1217 PF06748.12 KXL44541.1 - 0.029 14.4 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1217) SRP40_C PF05022.12 KXL44542.1 - 1.1e-20 74.2 0.3 1.1e-20 74.2 0.3 2.4 2 1 0 2 2 2 1 SRP40, C-terminal domain Pap_E4 PF02711.14 KXL44542.1 - 0.23 12.4 0.2 0.23 12.4 0.2 6.2 1 1 5 6 6 6 0 E4 protein NAD_binding_10 PF13460.6 KXL44543.1 - 5e-33 114.5 0.1 5.7e-33 114.3 0.1 1.0 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXL44543.1 - 3.9e-07 29.8 0.0 5.2e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KXL44543.1 - 0.0004 20.0 0.2 0.0016 18.0 0.2 1.9 1 1 0 1 1 1 1 NmrA-like family Methyltransf_3 PF01596.17 KXL44544.1 - 4.3e-11 42.4 0.0 5.8e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KXL44544.1 - 8.2e-10 39.7 0.1 1.4e-09 39.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.12 KXL44544.1 - 0.0029 17.3 0.0 0.0079 15.9 0.0 1.7 2 0 0 2 2 2 1 Cephalosporin hydroxylase HemX PF04375.14 KXL44544.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Gly_transf_sug PF04488.15 KXL44546.1 - 3.2e-13 50.1 0.1 5.3e-13 49.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KXL44546.1 - 1.9e-05 24.2 0.0 2.9e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein DUF4454 PF14628.6 KXL44546.1 - 0.22 11.3 0.0 0.36 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4454) Ank_2 PF12796.7 KXL44548.1 - 1.5e-13 51.2 0.4 1.7e-13 51.0 0.4 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXL44548.1 - 6e-12 45.8 0.3 1.5e-11 44.6 0.1 1.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXL44548.1 - 6.2e-12 45.5 1.5 2.7e-06 27.5 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KXL44548.1 - 1.4e-09 37.9 1.4 2.2e-05 24.7 0.2 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KXL44548.1 - 8.8e-08 31.8 0.3 0.0065 16.9 0.0 2.5 3 0 0 3 3 3 2 Ankyrin repeat AA_permease_2 PF13520.6 KXL44549.1 - 1.7e-54 185.3 53.1 2.1e-54 185.0 53.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXL44549.1 - 1.1e-24 86.9 45.6 1.5e-24 86.5 45.6 1.1 1 0 0 1 1 1 1 Amino acid permease Fungal_trans_2 PF11951.8 KXL44552.1 - 1.7e-09 37.0 0.2 2.4e-09 36.5 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL44552.1 - 3.6e-07 30.2 10.8 7.1e-07 29.2 10.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain His_Phos_1 PF00300.22 KXL44553.1 - 2.3e-15 56.8 0.0 3.2e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ran-binding PF05508.11 KXL44555.1 - 3.9e-96 321.7 0.0 5e-96 321.4 0.0 1.1 1 0 0 1 1 1 1 RanGTP-binding protein BUD22 PF09073.10 KXL44555.1 - 0.00081 18.9 0.6 0.0015 17.9 0.6 1.4 1 0 0 1 1 1 1 BUD22 GTP_EFTU PF00009.27 KXL44556.1 - 6.2e-42 143.3 0.0 1.4e-41 142.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KXL44556.1 - 1.5e-28 99.4 0.0 3.2e-28 98.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KXL44556.1 - 0.0021 18.4 0.0 0.0054 17.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXL44556.1 - 0.0024 17.9 0.1 0.013 15.6 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dehalogenase PF13486.6 KXL44556.1 - 0.063 12.7 0.2 8.2 5.7 0.0 2.3 2 0 0 2 2 2 0 Reductive dehalogenase subunit Ndc1_Nup PF09531.10 KXL44556.1 - 1.4 7.5 3.6 2.5 6.7 3.6 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CaM_bdg_C0 PF10562.9 KXL44557.1 - 6.1 7.0 5.5 5.9 7.0 0.9 2.4 2 0 0 2 2 2 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit 2OG-FeII_Oxy_2 PF13532.6 KXL44558.1 - 6.2e-29 101.6 0.0 5.1e-28 98.6 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ABC_export PF16962.5 KXL44559.1 - 0.24 9.8 0.1 0.34 9.3 0.1 1.1 1 0 0 1 1 1 0 Putative ABC exporter Ribosomal_L6 PF00347.23 KXL44560.1 - 1.8e-19 70.1 0.0 1.3e-11 45.0 0.0 2.8 2 1 0 2 2 2 2 Ribosomal protein L6 DUF3077 PF11275.8 KXL44562.1 - 0.057 13.6 0.2 0.16 12.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3077) AA_permease_2 PF13520.6 KXL44563.1 - 2.1e-08 33.5 13.8 2.7e-08 33.1 13.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXL44563.1 - 4.4e-06 25.6 10.7 5.7e-06 25.2 10.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXL44564.1 - 2.8e-12 46.2 13.4 3e-12 46.1 13.4 1.0 1 0 0 1 1 1 1 Amino acid permease CPP1-like PF11833.8 KXL44564.1 - 0.021 14.5 0.1 0.032 13.9 0.1 1.3 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF2433 PF10360.9 KXL44565.1 - 9.1e-49 164.7 0.0 1.6e-48 163.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.28 KXL44565.1 - 0.0018 18.8 0.0 0.004 17.7 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXL44565.1 - 0.002 18.3 0.0 0.0078 16.4 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TFIIA PF03153.13 KXL44565.1 - 0.3 11.0 16.2 0.43 10.5 16.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NPC1_N PF16414.5 KXL44566.1 - 1e-80 270.9 6.6 1.5e-80 270.3 6.6 1.3 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 KXL44566.1 - 3.6e-79 266.8 0.2 1.7e-78 264.6 0.2 2.0 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 KXL44566.1 - 5.1e-51 172.5 5.7 5.1e-51 172.5 5.7 3.6 4 0 0 4 4 4 1 Sterol-sensing domain of SREBP cleavage-activation Folate_rec PF03024.14 KXL44566.1 - 0.00068 19.5 1.8 0.0014 18.5 1.8 1.4 1 0 0 1 1 1 1 Folate receptor family MMPL PF03176.15 KXL44566.1 - 0.024 13.6 38.5 0.044 12.7 18.8 3.6 3 1 0 3 3 3 0 MMPL family ABC2_membrane PF01061.24 KXL44567.1 - 6.1e-31 107.5 26.0 9.5e-31 106.9 26.0 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KXL44567.1 - 8.5e-25 87.9 0.1 1.4e-24 87.1 0.1 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KXL44567.1 - 4.1e-05 23.5 0.2 0.00039 20.4 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 KXL44567.1 - 4.2e-05 23.5 0.1 0.35 10.6 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KXL44567.1 - 0.00018 21.2 0.0 0.00042 19.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXL44567.1 - 0.0005 20.5 0.3 0.001 19.5 0.1 1.6 2 0 0 2 2 1 1 AAA ATPase domain SMC_N PF02463.19 KXL44567.1 - 0.0012 18.4 0.1 0.0039 16.6 0.1 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXL44567.1 - 0.0029 17.9 0.0 0.0065 16.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXL44567.1 - 0.011 15.4 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KXL44567.1 - 0.012 14.7 0.1 0.02 13.9 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 KXL44567.1 - 0.012 15.3 0.2 0.027 14.2 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 KXL44567.1 - 0.024 14.2 0.1 0.04 13.5 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_13 PF13166.6 KXL44567.1 - 0.025 13.2 0.5 0.23 10.0 0.2 2.1 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KXL44567.1 - 0.026 14.4 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 KXL44567.1 - 0.031 14.7 0.3 0.12 12.8 0.1 2.2 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KXL44567.1 - 0.034 14.0 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 KXL44567.1 - 0.04 13.9 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KXL44567.1 - 0.043 13.5 0.1 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.6 KXL44567.1 - 0.055 14.0 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXL44567.1 - 0.059 13.8 0.0 0.28 11.6 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.6 KXL44567.1 - 0.071 13.1 0.0 0.18 11.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 KXL44567.1 - 0.077 13.2 0.1 0.17 12.1 0.0 1.6 2 0 0 2 2 1 0 AAA domain Rad17 PF03215.15 KXL44567.1 - 0.081 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain ABC2_membrane_3 PF12698.7 KXL44567.1 - 0.087 11.9 23.2 0.047 12.8 20.7 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein AAA_33 PF13671.6 KXL44567.1 - 0.094 12.9 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KXL44567.1 - 0.11 12.6 0.4 0.34 11.0 0.1 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.6 KXL44567.1 - 0.16 12.5 0.1 0.26 11.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KXL44567.1 - 0.18 11.4 0.1 0.34 10.5 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_35 PF14516.6 KXL44567.1 - 0.2 10.4 0.0 0.35 9.6 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain DUF423 PF04241.15 KXL44567.1 - 0.59 10.4 4.5 16 5.8 0.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF423) Aminotran_5 PF00266.19 KXL44568.1 - 1.4e-24 86.7 0.0 3.1e-18 65.9 0.0 2.8 1 1 1 2 2 2 2 Aminotransferase class-V Abhydrolase_3 PF07859.13 KXL44569.1 - 5.9e-11 42.6 0.0 1.1e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXL44569.1 - 0.00049 19.1 0.0 0.00072 18.5 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Glyco_hydro_cc PF11790.8 KXL44570.1 - 1.2e-58 198.5 0.2 1.4e-58 198.3 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Copper-fist PF00649.18 KXL44571.1 - 5.6e-18 64.2 0.9 5.6e-18 64.2 0.9 2.4 2 1 1 3 3 3 1 Copper fist DNA binding domain GPR15L PF15854.5 KXL44571.1 - 1.9 8.8 6.3 5.4 7.3 6.3 1.8 1 0 0 1 1 1 0 G-protein coupled receptor ligand 15 adh_short_C2 PF13561.6 KXL44572.1 - 1.2e-35 123.2 0.7 1.4e-35 123.0 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL44572.1 - 2.4e-26 92.4 0.0 3.1e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL44572.1 - 3.6e-06 27.0 0.0 7.3e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 KR domain Bac_luciferase PF00296.20 KXL44573.1 - 2.2e-51 175.2 0.3 3.3e-51 174.6 0.3 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase ADH_zinc_N PF00107.26 KXL44574.1 - 4e-11 43.0 0.1 6.2e-11 42.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXL44574.1 - 1.4e-10 41.0 0.0 5e-09 36.0 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Chlorovi_GP_rpt PF06598.11 KXL44574.1 - 0.4 10.8 2.8 0.62 10.2 0.2 2.4 2 0 0 2 2 2 0 Chlorovirus glycoprotein repeat Aa_trans PF01490.18 KXL44575.1 - 2.5e-20 72.6 32.2 3e-20 72.3 32.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein p450 PF00067.22 KXL44576.1 - 3.1e-15 55.9 0.0 3.7e-15 55.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 KXL44577.1 - 1.8e-26 92.8 0.0 3.1e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL44577.1 - 1.5e-09 37.8 10.1 2.8e-09 37.0 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2397 PF09660.10 KXL44577.1 - 0.14 11.0 0.1 0.22 10.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) Bac_luciferase PF00296.20 KXL44578.1 - 7e-56 189.9 0.4 1e-55 189.4 0.4 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase UCH PF00443.29 KXL44579.1 - 1.9e-49 168.5 0.0 2.6e-49 168.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXL44579.1 - 5.2e-15 55.9 0.0 3.1e-13 50.0 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 KXL44579.1 - 0.00086 19.8 0.0 0.0021 18.5 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain VHS PF00790.19 KXL44580.1 - 2.2e-36 124.8 0.0 2.2e-36 124.8 0.0 1.9 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 KXL44580.1 - 4.6e-17 61.9 3.9 8.6e-17 61.0 3.9 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 KXL44580.1 - 3.8e-08 32.7 7.3 0.0023 17.7 1.6 2.9 2 0 0 2 2 2 2 Ubiquitin interaction motif GAT PF03127.14 KXL44580.1 - 9.9e-05 22.6 0.6 0.00035 20.8 0.0 2.3 3 0 0 3 3 3 1 GAT domain FYVE_2 PF02318.16 KXL44580.1 - 0.0027 17.9 2.1 0.0056 16.9 2.1 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger Npa1 PF11707.8 KXL44580.1 - 0.083 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal zf-RING_2 PF13639.6 KXL44580.1 - 0.46 10.9 5.8 0.89 9.9 5.8 1.4 1 0 0 1 1 1 0 Ring finger domain Lsm_interact PF05391.11 KXL44581.1 - 0.4 10.2 2.3 1.1 8.8 2.3 1.8 1 0 0 1 1 1 0 Lsm interaction motif PEPCK_ATP PF01293.20 KXL44582.1 - 1.7e-216 719.4 0.0 2e-216 719.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 KXL44582.1 - 0.16 12.4 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KXL44582.1 - 0.17 12.1 0.1 0.4 10.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain UCH_1 PF13423.6 KXL44583.1 - 3e-86 289.9 0.6 4.1e-86 289.5 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 KXL44583.1 - 1.2e-16 61.7 0.0 2.4e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Exonuclease Flavoprotein PF02441.19 KXL44584.1 - 1.8e-20 73.3 0.0 2.7e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Flavoprotein PHY PF00360.20 KXL44585.1 - 4.1e-29 101.2 0.0 9.1e-29 100.1 0.0 1.5 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 KXL44585.1 - 6.4e-18 65.3 0.2 1.8e-17 63.9 0.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXL44585.1 - 5.5e-16 58.7 0.0 1.5e-15 57.3 0.0 1.8 1 1 0 1 1 1 1 Response regulator receiver domain GAF PF01590.26 KXL44585.1 - 6.7e-14 52.7 0.0 2.5e-12 47.6 0.0 2.5 2 0 0 2 2 2 1 GAF domain HisKA PF00512.25 KXL44585.1 - 1.5e-12 47.4 0.5 4.8e-12 45.7 0.5 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.11 KXL44585.1 - 4.7e-09 36.9 0.0 1.5e-08 35.3 0.0 1.9 1 0 0 1 1 1 1 PAS fold HATPase_c_5 PF14501.6 KXL44585.1 - 0.049 13.5 1.1 0.16 11.9 1.1 1.9 1 1 0 1 1 1 0 GHKL domain HATPase_c_3 PF13589.6 KXL44585.1 - 0.11 12.3 0.2 0.25 11.2 0.2 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Zn_clus PF00172.18 KXL44586.1 - 1.8e-10 40.8 10.7 2.9e-10 40.1 10.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXL44586.1 - 4e-05 22.8 0.0 8.4e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.25 KXL44587.1 - 2.9e-61 207.2 0.0 4.3e-61 206.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL44587.1 - 3e-30 105.4 0.0 4e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXL44587.1 - 0.00078 18.8 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXL44587.1 - 0.0023 17.3 0.1 0.0046 16.3 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXL44587.1 - 0.0053 16.7 0.4 0.041 13.8 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXL44587.1 - 0.012 14.4 0.0 0.023 13.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Endonuc_Holl PF10107.9 KXL44587.1 - 0.069 13.0 0.1 0.49 10.2 0.0 2.0 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Haspin_kinase PF12330.8 KXL44587.1 - 0.27 10.1 0.0 0.41 9.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Haspin_kinase PF12330.8 KXL44588.1 - 0.085 11.8 0.1 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Ribosomal_L39 PF00832.20 KXL44588.1 - 0.77 9.4 3.7 15 5.3 0.0 3.1 3 0 0 3 3 3 0 Ribosomal L39 protein UQ_con PF00179.26 KXL44589.1 - 2.1e-36 124.7 0.1 2.6e-36 124.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme MBOAT_2 PF13813.6 KXL44590.1 - 5e-18 65.2 0.8 5e-18 65.2 0.8 2.4 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family DEAD PF00270.29 KXL44591.1 - 2.5e-37 128.4 0.0 4.3e-37 127.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXL44591.1 - 1.7e-22 79.9 0.0 1e-20 74.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL44591.1 - 3.2e-05 24.0 0.0 7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KXL44591.1 - 0.04 13.6 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KXL44591.1 - 0.043 14.2 0.0 0.091 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 KXL44593.1 - 2.5e-70 236.8 0.0 3.9e-70 236.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL44593.1 - 4.8e-45 153.9 0.0 8.8e-45 153.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KXL44593.1 - 1.7e-22 79.6 0.2 5.2e-22 78.0 0.2 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 KXL44593.1 - 1.3e-06 27.5 1.1 4.4e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KXL44593.1 - 3.1e-06 26.7 0.1 7.5e-06 25.5 0.1 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KXL44593.1 - 0.043 13.7 1.2 0.52 10.2 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family TFIIA PF03153.13 KXL44593.1 - 0.48 10.4 19.0 0.77 9.7 19.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Haspin_kinase PF12330.8 KXL44593.1 - 2.8 6.8 6.9 0.3 10.0 0.9 2.2 2 1 0 2 2 2 0 Haspin like kinase domain Spt20 PF12090.8 KXL44594.1 - 2.1e-40 138.8 0.0 2.9e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Spt20 family Arylsulfotran_2 PF14269.6 KXL44595.1 - 1.5e-51 175.6 0.8 2.1e-51 175.1 0.1 1.6 2 0 0 2 2 2 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXL44595.1 - 7.7e-16 58.0 0.1 2.3e-15 56.4 0.1 1.7 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) MRG PF05712.13 KXL44597.1 - 2.2e-51 174.0 0.0 2.7e-51 173.7 0.0 1.0 1 0 0 1 1 1 1 MRG DUF2013 PF09431.10 KXL44599.1 - 1.2e-51 174.6 0.4 1.2e-51 174.6 0.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) NopRA1 PF16201.5 KXL44599.1 - 0.015 14.9 0.3 0.057 13.0 0.1 2.1 2 0 0 2 2 2 0 Nucleolar pre-ribosomal-associated protein 1 MFS_1 PF07690.16 KXL44600.1 - 9.8e-27 93.8 39.1 1e-24 87.1 32.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldedh PF00171.22 KXL44601.1 - 8.3e-08 31.2 0.3 0.0021 16.6 0.0 2.2 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Tox-ODYAM1 PF15642.6 KXL44601.1 - 2.5e-05 23.4 0.0 4.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Toxin in Odyssella and Amoebophilus FAA_hydrolase PF01557.18 KXL44603.1 - 3.2e-50 170.8 0.0 4.6e-50 170.3 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KXL44603.1 - 3e-15 56.3 0.0 5.6e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Cupin_2 PF07883.11 KXL44604.1 - 2.6e-07 30.2 0.0 4.6e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KXL44604.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Fungal_trans PF04082.18 KXL44605.1 - 1.3e-09 37.5 1.2 3.6e-09 36.0 0.9 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KXL44605.1 - 2e-08 34.2 10.6 0.00045 20.5 0.1 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.18 KXL44605.1 - 4.9e-06 26.5 15.1 4.9e-06 26.5 15.1 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 KXL44605.1 - 6.9e-05 23.1 4.0 0.0012 19.2 1.4 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KXL44605.1 - 0.00016 21.6 10.0 0.11 12.5 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXL44605.1 - 0.00023 21.4 3.2 0.2 12.0 2.2 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KXL44605.1 - 0.00044 20.8 17.3 0.017 15.9 4.5 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KXL44605.1 - 0.039 13.7 13.1 0.05 13.4 0.1 2.9 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-met PF12874.7 KXL44605.1 - 0.1 13.0 4.0 0.6 10.6 2.9 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Peptidase_S15 PF02129.18 KXL44606.1 - 6.8e-45 153.7 0.3 1e-44 153.2 0.3 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 KXL44606.1 - 1.7e-44 152.5 0.4 2.7e-44 151.8 0.4 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 KXL44606.1 - 0.012 14.9 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 AXE1 PF05448.12 KXL44606.1 - 0.098 11.3 0.1 11 4.6 0.0 2.2 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) LigB PF02900.18 KXL44607.1 - 6.5e-16 58.2 0.0 7.6e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase DUF2828 PF11443.8 KXL44608.1 - 2.5e-232 772.5 0.0 2.3e-230 766.0 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF2828) Nitroreductase PF00881.24 KXL44608.1 - 0.046 13.8 0.0 0.092 12.8 0.0 1.4 1 0 0 1 1 1 0 Nitroreductase family BLOC1_2 PF10046.9 KXL44609.1 - 0.017 15.4 0.7 0.026 14.8 0.7 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 JIP_LZII PF16471.5 KXL44609.1 - 0.019 15.1 1.3 0.03 14.5 0.3 1.7 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Mito_carr PF00153.27 KXL44610.1 - 2.9e-56 187.4 0.1 1.7e-18 66.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF760 PF05542.11 KXL44610.1 - 0.18 12.2 0.9 0.51 10.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF760) Peptidase_C2 PF00648.21 KXL44611.1 - 1.4e-26 93.2 0.0 2.2e-25 89.3 0.0 2.1 1 1 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KXL44611.1 - 6.7e-11 42.6 0.0 7.5e-09 36.0 0.1 3.2 3 1 0 3 3 3 1 Calpain large subunit, domain III ARID PF01388.21 KXL44613.1 - 1.7e-15 57.5 0.0 5.6e-15 55.8 0.0 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain GEMIN8 PF15348.6 KXL44613.1 - 1.1 9.5 11.7 0.76 10.0 9.0 2.1 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 COX6B PF02297.17 KXL44614.1 - 2.8e-23 81.9 2.0 3.4e-23 81.7 2.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Oxysterol_BP PF01237.18 KXL44615.1 - 1.6e-54 185.2 4.1 2.1e-52 178.2 4.1 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein AflR PF08493.10 KXL44615.1 - 0.46 9.9 6.0 0.81 9.1 6.0 1.3 1 0 0 1 1 1 0 Aflatoxin regulatory protein Pox_F17 PF04767.12 KXL44616.1 - 0.49 10.9 2.7 11 6.6 1.6 2.1 2 0 0 2 2 2 0 DNA-binding 11 kDa phosphoprotein KH_1 PF00013.29 KXL44617.1 - 2.4e-07 30.5 0.0 2.3e-06 27.3 0.0 2.2 2 0 0 2 2 2 1 KH domain ACT PF01842.25 KXL44618.1 - 1.1e-14 53.8 0.1 2.3e-14 52.9 0.1 1.5 1 0 0 1 1 1 1 ACT domain ALS_ss_C PF10369.9 KXL44618.1 - 1.9e-14 53.6 0.0 1.6e-13 50.7 0.0 2.2 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT_5 PF13710.6 KXL44618.1 - 2.1e-08 33.9 0.0 3.4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 ACT domain MEIOC PF15189.6 KXL44618.1 - 0.088 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Meiosis-specific coiled-coil domain-containing protein MEIOC DUF3712 PF12505.8 KXL44619.1 - 0.17 12.1 0.0 12 6.2 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3712) OTCace_N PF02729.21 KXL44620.1 - 1e-43 148.9 0.1 1.4e-43 148.4 0.1 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 KXL44620.1 - 9.2e-40 136.3 0.0 1.7e-39 135.5 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain zf-CCHC_3 PF13917.6 KXL44622.1 - 6.3e-11 42.1 0.3 2.7e-10 40.0 0.3 2.2 1 0 0 1 1 1 1 Zinc knuckle LAP1C PF05609.12 KXL44622.1 - 5.2 6.0 11.6 6.1 5.8 11.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) R3H PF01424.22 KXL44623.1 - 2.1e-09 37.3 0.0 5.1e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 R3H domain SUZ PF12752.7 KXL44623.1 - 2.7e-09 37.7 1.1 2.7e-09 37.7 1.1 5.0 5 2 0 5 5 5 1 SUZ domain UCR_14kD PF02271.16 KXL44624.1 - 1.4e-32 111.6 2.0 1.6e-32 111.4 2.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit HhH-GPD PF00730.25 KXL44625.1 - 3.3e-13 50.0 0.0 5.5e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Hpr_kinase_C PF07475.12 KXL44625.1 - 0.069 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain SPX PF03105.19 KXL44626.1 - 0.00069 19.6 21.5 0.0064 16.5 0.3 4.5 2 2 1 4 4 4 3 SPX domain VTC PF09359.10 KXL44626.1 - 0.0016 17.9 0.0 0.22 10.9 0.0 2.6 1 1 0 1 1 1 1 VTC domain MARVEL PF01284.23 KXL44626.1 - 0.56 10.2 4.2 1 9.4 4.2 1.3 1 0 0 1 1 1 0 Membrane-associating domain DUF2754 PF10953.8 KXL44626.1 - 1 9.7 3.1 2.5 8.4 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2754) Mito_carr PF00153.27 KXL44627.1 - 5.3e-44 148.1 1.0 2.2e-22 78.8 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein UCR_14kD PF02271.16 KXL44628.1 - 4.4e-20 71.5 0.0 5.1e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Mito_carr PF00153.27 KXL44630.1 - 2.6e-25 88.1 2.2 2e-17 62.9 0.3 2.7 2 1 0 2 2 2 2 Mitochondrial carrier protein Anp1 PF03452.14 KXL44632.1 - 1.4e-107 359.1 0.0 1.6e-107 358.8 0.0 1.0 1 0 0 1 1 1 1 Anp1 Remorin_N PF03766.13 KXL44632.1 - 0.14 12.2 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Remorin, N-terminal region DDE_1 PF03184.19 KXL44633.1 - 4.2e-16 59.1 0.0 6.4e-16 58.5 0.0 1.2 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KXL44633.1 - 0.01 15.6 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Ecm33 PF12454.8 KXL44636.1 - 6.6e-10 39.0 3.0 9.6e-10 38.5 1.5 2.2 2 0 0 2 2 2 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.24 KXL44636.1 - 9.1e-08 32.2 0.6 0.055 13.6 0.0 3.8 2 2 0 2 2 2 2 Receptor L domain DUF418 PF04235.12 KXL44637.1 - 0.15 12.0 6.2 0.18 11.7 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF418) PI-PLC-X PF00388.19 KXL44637.1 - 0.17 11.5 0.1 0.24 11.0 0.1 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain DUF2512 PF10710.9 KXL44637.1 - 8.1 6.1 11.1 0.16 11.6 0.7 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2512) Glycos_transf_4 PF00953.21 KXL44638.1 - 6.2e-32 110.8 8.7 6.2e-32 110.8 8.7 2.2 2 1 0 2 2 2 1 Glycosyl transferase family 4 WD40 PF00400.32 KXL44639.1 - 3e-13 50.0 10.3 6.9e-05 23.5 0.1 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KXL44639.1 - 0.028 13.4 1.0 9.4 5.1 0.2 3.4 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KXL44639.1 - 0.056 12.1 0.1 8.6 4.9 0.5 2.4 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Lipase_GDSL PF00657.22 KXL44640.1 - 9.8e-10 38.7 0.0 1.3e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KXL44640.1 - 1.4e-06 28.8 0.5 3.1e-06 27.7 0.2 1.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Pro_isomerase PF00160.21 KXL44641.1 - 1e-44 152.6 0.0 1.5e-44 152.1 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Nucleoporin_N PF08801.11 KXL44642.1 - 4.2e-74 249.9 0.0 5.8e-74 249.4 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 KXL44642.1 - 1.6e-46 159.2 5.2 2.2e-46 158.8 3.0 1.9 1 1 1 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal zf-C2H2_4 PF13894.6 KXL44643.1 - 4e-08 33.4 19.7 0.00054 20.6 0.6 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KXL44643.1 - 1.2e-07 31.8 24.1 0.0011 19.3 0.8 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KXL44643.1 - 8.9e-07 28.8 18.1 0.00034 20.5 5.7 2.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXL44643.1 - 0.00028 21.2 22.9 0.0023 18.3 1.5 4.7 5 0 0 5 5 5 2 Zinc-finger double domain zf_UBZ PF18439.1 KXL44643.1 - 0.0019 17.7 3.1 0.59 9.8 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 KXL44643.1 - 0.0041 17.4 20.4 0.011 16.0 0.9 3.7 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding HypA PF01155.19 KXL44643.1 - 0.024 14.7 0.2 0.048 13.7 0.2 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Tnp_zf-ribbon_2 PF13842.6 KXL44643.1 - 0.1 13.4 2.2 14 6.6 0.2 2.6 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon zf_C2H2_ZHX PF18387.1 KXL44643.1 - 0.11 12.1 5.5 0.75 9.5 0.8 2.5 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-Di19 PF05605.12 KXL44643.1 - 0.23 11.8 11.6 2.2 8.6 0.1 2.9 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DUF2197 PF09963.9 KXL44643.1 - 0.27 11.5 2.7 1.9 8.8 2.6 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-MYST PF17772.1 KXL44643.1 - 0.4 10.3 1.8 4.5 6.9 0.1 2.4 1 1 1 2 2 2 0 MYST family zinc finger domain XPA_N PF01286.18 KXL44643.1 - 2 8.6 8.2 3.8 7.6 0.4 2.7 3 0 0 3 3 3 0 XPA protein N-terminal zf-C2H2_11 PF16622.5 KXL44643.1 - 2 8.3 5.6 19 5.2 0.7 3.7 4 0 0 4 4 4 0 zinc-finger C2H2-type LIM PF00412.22 KXL44643.1 - 3.1 8.1 9.4 19 5.6 9.4 2.1 1 1 0 1 1 1 0 LIM domain PHD PF00628.29 KXL44643.1 - 3.1 7.7 8.8 1.5 8.7 4.8 2.3 2 1 0 2 2 2 0 PHD-finger Actin_micro PF17003.5 KXL44643.1 - 7 5.7 6.5 48 3.0 6.5 2.0 1 1 0 1 1 1 0 Putative actin-like family MTP18 PF10558.9 KXL44644.1 - 7.8e-80 266.8 0.3 1e-79 266.5 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) ATP19 PF11022.8 KXL44645.1 - 4.6e-26 91.0 0.0 5.3e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 ATP synthase subunit K Halogen_Hydrol PF10112.9 KXL44645.1 - 0.18 11.8 0.0 0.18 11.8 0.0 1.0 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein TGT PF01702.18 KXL44646.1 - 1.5e-140 468.3 0.0 1.8e-140 468.1 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase SLAC1 PF03595.17 KXL44647.1 - 4.8e-78 262.7 47.6 5.4e-78 262.5 47.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel GLTT PF01744.20 KXL44647.1 - 0.075 12.8 1.1 0.17 11.7 1.1 1.7 1 0 0 1 1 1 0 GLTT repeat (6 copies) SecG PF03840.14 KXL44647.1 - 0.1 12.7 0.1 0.1 12.7 0.1 3.7 5 0 0 5 5 5 0 Preprotein translocase SecG subunit PAN_3 PF08277.12 KXL44649.1 - 0.037 13.8 1.3 0.16 11.8 1.3 2.1 1 0 0 1 1 1 0 PAN-like domain MAP7 PF05672.11 KXL44649.1 - 4.8 6.9 62.5 9.8 5.8 62.5 1.4 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family ARGLU PF15346.6 KXL44649.1 - 7.3 6.5 50.1 11 5.9 50.1 1.1 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 YqeY PF09424.10 KXL44650.1 - 1.7e-20 73.6 8.6 2.4e-20 73.1 8.6 1.1 1 0 0 1 1 1 1 Yqey-like protein zf-FPG_IleRS PF06827.14 KXL44650.1 - 0.024 14.5 0.3 0.041 13.7 0.3 1.4 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS BPL_N PF09825.9 KXL44650.1 - 0.038 13.1 0.4 0.049 12.7 0.4 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal CM_2 PF01817.21 KXL44650.1 - 0.078 13.3 0.6 0.19 12.1 0.6 1.8 1 1 0 1 1 1 0 Chorismate mutase type II DUF2781 PF10914.8 KXL44651.1 - 1.5e-42 145.5 9.6 1.7e-42 145.3 9.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) E1-E2_ATPase PF00122.20 KXL44654.1 - 6.6e-38 130.0 8.5 3.3e-37 127.8 0.0 3.8 4 1 0 4 4 4 2 E1-E2 ATPase Hydrolase PF00702.26 KXL44654.1 - 1.3e-16 61.5 0.0 4.2e-16 59.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXL44654.1 - 8.2e-12 44.6 0.0 2.8e-11 42.9 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXL44654.1 - 0.0015 18.4 0.1 0.0036 17.1 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXL44654.1 - 0.0034 17.4 0.0 0.008 16.2 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) adh_short_C2 PF13561.6 KXL44655.1 - 4.6e-59 199.8 0.1 5.6e-59 199.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL44655.1 - 2.3e-43 147.9 0.1 3.3e-43 147.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL44655.1 - 5.3e-11 42.7 0.3 2.6e-10 40.5 0.0 1.9 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 KXL44655.1 - 0.0019 17.4 0.0 0.0035 16.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KXL44655.1 - 0.011 15.2 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 KXL44656.1 - 1.7e-13 50.3 25.8 2.2e-09 36.7 25.3 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily GP3 PF03076.14 KXL44656.1 - 1.8e-05 24.9 3.1 0.0058 16.7 0.2 2.5 2 0 0 2 2 2 2 Equine arteritis virus GP3 Sugar_tr PF00083.24 KXL44656.1 - 0.0013 17.7 2.8 0.0013 17.7 2.8 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter DUF2177 PF09945.9 KXL44656.1 - 0.076 13.1 0.1 0.076 13.1 0.1 2.8 2 1 0 3 3 3 0 Predicted membrane protein (DUF2177) Fungal_trans PF04082.18 KXL44657.1 - 0.018 14.1 0.3 0.046 12.8 0.1 1.8 2 1 0 2 2 2 0 Fungal specific transcription factor domain PHD PF00628.29 KXL44660.1 - 7.3e-08 32.2 6.8 1.5e-07 31.2 6.8 1.6 1 0 0 1 1 1 1 PHD-finger SET PF00856.28 KXL44660.1 - 1.6e-07 31.9 0.0 9.1e-07 29.4 0.0 2.2 3 1 0 3 3 3 1 SET domain COesterase PF00135.28 KXL44662.1 - 1.5e-81 274.8 0.0 4.4e-81 273.3 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXL44662.1 - 4.9e-09 36.3 0.1 1.4e-08 34.8 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXL44662.1 - 0.0011 18.5 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_M1 PF01433.20 KXL44664.1 - 6.8e-43 146.8 0.2 9.5e-43 146.3 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KXL44664.1 - 6.9e-37 126.0 0.0 1.4e-36 125.0 0.0 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KXL44664.1 - 1.4e-28 100.3 0.0 2.3e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain TbpB_B_D PF01298.18 KXL44664.1 - 0.075 13.4 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 C-lobe and N-lobe beta barrels of Tf-binding protein B Peptidase_MA_2 PF13485.6 KXL44664.1 - 0.095 12.4 0.2 0.17 11.5 0.2 1.4 1 0 0 1 1 1 0 Peptidase MA superfamily Peptidase_M61 PF05299.12 KXL44664.1 - 0.25 11.7 2.4 4.5 7.7 2.4 2.5 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Pkinase PF00069.25 KXL44665.1 - 1.8e-11 44.0 0.0 3.3e-09 36.5 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXL44665.1 - 1.4e-09 37.6 0.0 2.2e-08 33.7 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXL44665.1 - 0.015 14.7 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.11 KXL44665.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) AIG2_2 PF13772.6 KXL44666.1 - 1.2e-08 35.3 0.1 6.2e-08 32.9 0.1 2.2 2 1 0 2 2 2 1 AIG2-like family GGACT PF06094.12 KXL44666.1 - 1.6e-07 31.9 0.2 2.4e-07 31.4 0.2 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like ChaC PF04752.12 KXL44666.1 - 0.00025 21.1 0.6 0.00065 19.8 0.6 1.6 1 1 0 1 1 1 1 ChaC-like protein MAPEG PF01124.18 KXL44667.1 - 4e-17 62.3 0.8 5.6e-17 61.9 0.8 1.1 1 0 0 1 1 1 1 MAPEG family zf-C2H2 PF00096.26 KXL44668.1 - 0.00062 20.1 20.9 0.006 17.0 2.0 4.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXL44668.1 - 0.0012 19.5 20.1 0.016 16.0 1.4 4.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KXL44668.1 - 0.0029 17.3 0.9 0.0029 17.3 0.9 3.6 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2HE PF16278.5 KXL44668.1 - 0.013 15.9 3.8 0.42 11.1 0.1 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 KXL44668.1 - 0.081 13.3 3.3 0.11 13.0 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXL44668.1 - 0.091 13.1 3.0 0.24 11.8 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf_Hakai PF18408.1 KXL44668.1 - 0.92 9.3 7.1 0.11 12.2 1.2 2.5 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain zf-C2H2_11 PF16622.5 KXL44668.1 - 1.3 8.8 4.8 7.3 6.5 0.2 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2 PF00096.26 KXL44669.1 - 0.00022 21.5 30.4 0.021 15.3 0.8 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXL44669.1 - 0.007 17.1 24.9 0.096 13.6 0.5 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXL44669.1 - 0.043 14.2 1.6 0.043 14.2 1.6 4.3 4 1 0 4 4 4 0 Zinc-finger double domain zf-C2H2 PF00096.26 KXL44670.1 - 0.002 18.5 21.6 0.13 12.8 1.4 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXL44670.1 - 0.009 16.4 18.4 0.06 13.8 0.7 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-4CXXC_R1 PF10497.9 KXL44670.1 - 0.042 14.1 4.3 0.13 12.5 4.3 1.8 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Zn_ribbon_SprT PF17283.2 KXL44670.1 - 3.6 7.6 6.5 11 6.0 4.3 2.7 1 1 0 1 1 1 0 SprT-like zinc ribbon domain zf-C2H2_4 PF13894.6 KXL44671.1 - 0.0012 19.5 11.4 0.84 10.6 1.3 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KXL44671.1 - 0.0049 17.2 11.1 0.13 12.8 2.2 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXL44671.1 - 0.015 15.7 11.3 0.35 11.4 0.3 3.7 3 0 0 3 3 3 0 Zinc-finger double domain zf-Di19 PF05605.12 KXL44671.1 - 0.26 11.6 7.4 0.082 13.2 2.0 2.5 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-HYPF PF07503.12 KXL44671.1 - 2 8.3 6.3 1.2 8.9 1.7 2.6 2 0 0 2 2 2 0 HypF finger GFA PF04828.14 KXL44672.1 - 2.2e-08 34.3 0.2 2.2e-08 34.3 0.2 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.11 KXL44672.1 - 0.031 14.5 0.1 0.031 14.5 0.1 2.2 2 2 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-NADH-PPase PF09297.11 KXL44672.1 - 0.033 13.9 0.8 0.033 13.9 0.8 2.0 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.6 KXL44672.1 - 0.19 11.7 0.0 0.19 11.7 0.0 2.7 3 0 0 3 3 3 0 Nudix N-terminal ORC4_C PF14629.6 KXL44673.1 - 1.2e-39 135.9 0.0 2.4e-39 135.0 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 KXL44673.1 - 3.8e-12 46.9 0.1 8.3e-12 45.8 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXL44673.1 - 1.7e-08 34.8 0.1 4.8e-08 33.4 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KXL44673.1 - 7.1e-06 26.5 0.0 5.3e-05 23.7 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 KXL44673.1 - 3.5e-05 23.2 0.0 9.8e-05 21.7 0.0 1.7 1 0 0 1 1 1 1 KAP family P-loop domain NB-ARC PF00931.22 KXL44673.1 - 4.9e-05 22.6 0.2 0.00011 21.4 0.2 1.6 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 KXL44673.1 - 5.4e-05 23.2 0.2 0.00063 19.7 0.2 2.2 1 1 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 KXL44673.1 - 5.8e-05 23.1 0.1 0.00016 21.7 0.1 1.8 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea T2SSE PF00437.20 KXL44673.1 - 0.00011 21.4 0.1 0.0002 20.5 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF815 PF05673.13 KXL44673.1 - 0.00028 20.1 0.2 0.00065 18.9 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 KXL44673.1 - 0.00029 20.9 0.0 0.00094 19.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KXL44673.1 - 0.0013 19.2 0.7 0.018 15.5 0.0 2.5 2 0 0 2 2 2 1 ABC transporter TrwB_AAD_bind PF10412.9 KXL44673.1 - 0.0025 16.8 0.1 0.0052 15.7 0.1 1.4 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_21 PF13304.6 KXL44673.1 - 0.003 17.4 0.1 0.39 10.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system Arf PF00025.21 KXL44673.1 - 0.004 16.6 0.0 2.7 7.4 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.6 KXL44673.1 - 0.0042 16.8 0.1 0.0093 15.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain cobW PF02492.19 KXL44673.1 - 0.0055 16.3 0.0 0.016 14.8 0.0 1.8 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain TniB PF05621.11 KXL44673.1 - 0.007 15.8 0.1 0.089 12.2 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein AAA_30 PF13604.6 KXL44673.1 - 0.0095 15.7 0.0 0.029 14.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXL44673.1 - 0.014 15.7 0.2 0.043 14.1 0.1 2.0 2 1 0 2 2 1 0 AAA domain ATP-synt_ab PF00006.25 KXL44673.1 - 0.018 14.7 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 KXL44673.1 - 0.02 14.4 0.0 0.065 12.7 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 KXL44673.1 - 0.025 14.7 0.0 0.07 13.2 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.20 KXL44673.1 - 0.033 13.3 0.2 0.064 12.4 0.2 1.4 1 0 0 1 1 1 0 G-protein alpha subunit RsgA_GTPase PF03193.16 KXL44673.1 - 0.043 13.7 0.1 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 RsgA GTPase FtsK_SpoIIIE PF01580.18 KXL44673.1 - 0.045 13.1 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_33 PF13671.6 KXL44673.1 - 0.053 13.7 0.0 0.32 11.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KXL44673.1 - 0.063 13.8 0.0 0.28 11.7 0.0 2.2 2 0 0 2 2 1 0 AAA domain DLIC PF05783.11 KXL44673.1 - 0.071 11.9 0.0 0.071 11.9 0.0 2.5 2 1 1 3 3 3 0 Dynein light intermediate chain (DLIC) AAA_28 PF13521.6 KXL44673.1 - 0.076 13.3 1.5 0.11 12.7 0.0 2.1 3 0 0 3 3 1 0 AAA domain AAA_23 PF13476.6 KXL44673.1 - 0.083 13.4 2.6 0.15 12.6 0.2 2.3 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KXL44673.1 - 0.11 12.7 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Pinin_SDK_N PF04697.13 KXL44673.1 - 1.5 9.5 7.5 0.33 11.6 3.9 1.8 2 0 0 2 2 1 0 pinin/SDK conserved region adh_short PF00106.25 KXL44675.1 - 3.1e-83 278.0 11.9 3.1e-45 154.0 1.7 2.7 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXL44675.1 - 4.9e-65 219.3 3.8 4.3e-34 118.1 0.4 2.6 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 KXL44675.1 - 1.7e-33 114.8 0.0 5.3e-33 113.2 0.0 1.8 2 0 0 2 2 2 1 MaoC like domain KR PF08659.10 KXL44675.1 - 4.4e-29 101.7 3.6 7.8e-15 55.2 0.2 2.4 2 0 0 2 2 2 2 KR domain MaoC_dehydrat_N PF13452.6 KXL44675.1 - 0.0016 18.6 0.0 1.1 9.4 0.0 2.4 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.19 KXL44675.1 - 0.0027 17.1 0.1 0.0098 15.2 0.1 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain adh_short PF00106.25 KXL44676.1 - 5.1e-32 110.9 0.0 6.6e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL44676.1 - 1.5e-26 93.4 0.0 2.1e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL44676.1 - 2.8e-05 24.1 0.0 0.00062 19.7 0.0 2.2 1 1 0 1 1 1 1 KR domain MoCF_biosynth PF00994.24 KXL44676.1 - 0.12 12.0 0.2 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 Probable molybdopterin binding domain AAA_33 PF13671.6 KXL44677.1 - 0.0055 16.9 0.0 0.0098 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KXL44677.1 - 0.026 14.2 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NACHT PF05729.12 KXL44677.1 - 0.026 14.4 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 KXL44677.1 - 0.027 14.5 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MeaB PF03308.16 KXL44677.1 - 0.035 13.1 0.0 0.068 12.1 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 KXL44677.1 - 0.041 13.1 0.0 0.091 11.9 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.19 KXL44677.1 - 0.045 13.3 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 KXL44677.1 - 0.047 14.1 0.1 0.14 12.5 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 KXL44677.1 - 0.049 13.5 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 KXL44677.1 - 0.062 13.9 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KXL44677.1 - 0.096 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 KXL44677.1 - 0.11 13.1 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Integrase_DNA PF02920.15 KXL44677.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 DNA binding domain of tn916 integrase CbiA PF01656.23 KXL44677.1 - 0.15 12.1 0.2 0.28 11.3 0.2 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA PF00004.29 KXL44677.1 - 0.16 12.4 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cys_Met_Meta_PP PF01053.20 KXL44678.1 - 1.1e-132 442.3 0.0 1.2e-132 442.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KXL44678.1 - 3e-06 26.7 0.0 4.6e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KXL44678.1 - 0.0001 21.4 0.0 0.00028 20.0 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 KXL44678.1 - 0.0014 17.2 0.1 0.0049 15.4 0.1 1.8 1 1 0 1 1 1 1 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.17 KXL44678.1 - 0.038 13.3 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Yip1 PF04893.17 KXL44679.1 - 3.4e-13 49.7 13.7 5.1e-13 49.1 13.7 1.4 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 KXL44679.1 - 0.00066 19.5 4.7 0.0012 18.6 4.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) DUF2070 PF09843.9 KXL44679.1 - 5.1 5.3 9.5 6.6 4.9 9.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) NAT PF04768.13 KXL44680.1 - 2e-52 177.3 0.0 6.6e-52 175.6 0.0 1.9 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 KXL44680.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Amino acid kinase family PigN PF04987.14 KXL44681.1 - 8.1e-157 522.7 28.0 1e-156 522.3 28.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Sulfatase PF00884.23 KXL44681.1 - 9.3e-10 38.4 0.0 6.1e-09 35.7 0.0 2.0 1 1 1 2 2 2 1 Sulfatase Phosphodiest PF01663.22 KXL44681.1 - 1.7e-09 37.7 4.9 3.2e-08 33.6 4.9 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KXL44681.1 - 0.00069 19.1 0.1 0.0012 18.2 0.1 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sensor_TM1 PF13755.6 KXL44681.1 - 0.0031 17.2 0.1 0.011 15.4 0.1 2.0 1 0 0 1 1 1 1 Sensor N-terminal transmembrane domain FlgM PF04316.13 KXL44681.1 - 0.097 13.1 0.2 0.23 11.9 0.2 1.5 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM ATP-synt_F PF01990.17 KXL44682.1 - 1.1e-31 109.0 0.1 1.3e-31 108.8 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF3484 PF11983.8 KXL44682.1 - 0.084 14.0 0.3 0.43 11.7 0.3 2.1 1 1 0 1 1 1 0 Membrane-attachment and polymerisation-promoting switch E1_DerP2_DerF2 PF02221.15 KXL44683.1 - 6.1e-31 107.6 1.4 7.7e-31 107.3 1.4 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 KXL44683.1 - 6e-05 23.4 0.0 0.00011 22.5 0.0 1.4 1 1 0 1 1 1 1 ML-like domain Big_9 PF17963.1 KXL44683.1 - 0.0012 19.5 0.0 0.0024 18.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial Ig domain MG2 PF01835.19 KXL44683.1 - 0.025 15.0 0.0 0.047 14.2 0.0 1.5 1 1 0 1 1 1 0 MG2 domain Y_Y_Y PF07495.13 KXL44683.1 - 0.033 14.1 0.1 11 6.1 0.0 2.3 2 0 0 2 2 2 0 Y_Y_Y domain DUF4832 PF16116.5 KXL44683.1 - 0.075 12.9 0.4 0.93 9.3 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4832) NPCBM_assoc PF10633.9 KXL44683.1 - 0.097 12.9 0.5 1.2 9.4 0.0 2.5 3 0 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Alph_Pro_TM PF09608.10 KXL44683.1 - 0.1 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) DUF4981 PF16353.5 KXL44683.1 - 0.14 12.6 0.3 0.46 11.0 0.0 1.9 2 1 0 2 2 2 0 Domain of unknown function(DUF4981) Coatomer_WDAD PF04053.14 KXL44684.1 - 3.9e-170 566.7 0.0 8e-170 565.7 0.0 1.5 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 KXL44684.1 - 6.8e-38 128.0 7.5 1e-05 26.2 0.0 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL44684.1 - 2.3e-08 34.2 0.0 2.8 8.3 0.0 6.3 4 2 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXL44684.1 - 3.2e-05 22.8 2.5 0.085 11.5 0.0 4.1 1 1 3 4 4 4 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 KXL44684.1 - 0.069 13.2 0.0 12 6.0 0.0 3.4 2 2 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.11 KXL44684.1 - 0.11 12.4 0.0 21 4.9 0.0 3.8 4 1 1 5 5 5 0 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KXL44684.1 - 0.11 11.8 0.0 39 3.4 0.0 3.2 3 0 0 3 3 3 0 WD40-like domain Fungal_trans PF04082.18 KXL44685.1 - 1.9e-32 112.3 0.0 3.9e-32 111.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL44685.1 - 1.1e-07 31.9 8.4 1.8e-07 31.2 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rox3 PF08633.10 KXL44685.1 - 0.0015 18.9 0.2 0.0043 17.4 0.2 1.8 1 0 0 1 1 1 1 Rox3 mediator complex subunit Peptidase_M24 PF00557.24 KXL44686.1 - 1.4e-56 191.5 0.0 1.8e-56 191.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KXL44686.1 - 1.8e-22 79.3 0.0 3.4e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF3793 PF12672.7 KXL44686.1 - 0.13 12.3 0.2 0.42 10.7 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3793) KRE9 PF05390.11 KXL44687.1 - 1.3e-16 61.2 7.6 1.3e-16 61.2 7.6 2.4 2 1 1 3 3 3 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.9 KXL44687.1 - 8.4e-15 55.3 0.7 8.4e-15 55.3 0.7 2.5 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Methyltransf_23 PF13489.6 KXL44688.1 - 5.5e-12 45.8 0.0 9.8e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL44688.1 - 1.7e-07 31.9 0.1 1.3e-06 29.0 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL44688.1 - 1.1e-06 29.2 0.0 2.8e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL44688.1 - 2.8e-06 28.0 0.0 9.6e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL44688.1 - 5.3e-06 26.3 0.0 0.0089 15.8 0.2 2.3 2 0 0 2 2 2 2 Methyltransferase domain CMAS PF02353.20 KXL44688.1 - 0.047 13.0 0.0 0.11 11.8 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 KXL44688.1 - 0.099 12.7 0.0 0.38 10.8 0.0 1.8 2 0 0 2 2 2 0 FtsJ-like methyltransferase Sugar_tr PF00083.24 KXL44690.1 - 1.8e-52 178.8 24.9 4.3e-28 98.4 5.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXL44690.1 - 4.5e-15 55.4 37.9 3.9e-08 32.6 17.0 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily DMT_YdcZ PF04657.13 KXL44690.1 - 0.019 15.2 0.7 0.019 15.2 0.7 3.8 4 0 0 4 4 4 0 Putative inner membrane exporter, YdcZ Arv1 PF04161.13 KXL44691.1 - 6.2e-68 229.1 0.0 1e-67 228.4 0.0 1.3 1 1 0 1 1 1 1 Arv1-like family ATP_synt_H PF05493.13 KXL44692.1 - 1.3e-23 83.2 2.8 1.5e-23 83.0 2.8 1.1 1 0 0 1 1 1 1 ATP synthase subunit H Yip1 PF04893.17 KXL44692.1 - 0.41 10.3 7.8 0.52 10.0 7.8 1.1 1 0 0 1 1 1 0 Yip1 domain adh_short PF00106.25 KXL44693.1 - 8.6e-43 146.1 0.1 1.2e-42 145.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL44693.1 - 8.2e-26 91.0 0.0 1.1e-25 90.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL44693.1 - 8.3e-06 25.8 0.1 1.4e-05 25.1 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXL44693.1 - 0.00014 21.1 0.3 0.0002 20.6 0.3 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KXL44693.1 - 0.036 13.5 0.1 0.051 13.0 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 KXL44693.1 - 0.11 12.4 0.4 0.23 11.3 0.2 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Zn_clus PF00172.18 KXL44694.1 - 2.1e-08 34.2 11.0 3.7e-08 33.4 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXL44694.1 - 1.5e-05 24.2 0.1 9e-05 21.6 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain PSI_integrin PF17205.3 KXL44694.1 - 0.015 15.1 0.8 0.032 14.0 0.8 1.6 1 0 0 1 1 1 0 Integrin plexin domain AA_permease_2 PF13520.6 KXL44695.1 - 3.7e-51 174.3 49.3 2e-50 171.9 49.3 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXL44695.1 - 8.1e-29 100.5 32.1 8.1e-29 100.5 32.1 1.5 2 0 0 2 2 2 1 Amino acid permease ArfGap PF01412.18 KXL44696.1 - 2.1e-33 114.9 0.0 3.4e-33 114.2 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF2415 PF10313.9 KXL44697.1 - 1.6e-15 56.7 0.0 3.6e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) PD40 PF07676.12 KXL44697.1 - 0.024 14.6 0.1 3 7.9 0.0 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 KXL44697.1 - 0.029 14.8 1.5 13 6.5 0.1 4.2 4 0 0 4 4 4 0 PQQ-like domain Mannitol_dh_C PF08125.13 KXL44698.1 - 1.5e-40 139.2 0.0 2.4e-40 138.6 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 KXL44698.1 - 8.6e-16 58.4 0.0 4.7e-15 56.0 0.0 2.1 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain 3HCDH_N PF02737.18 KXL44698.1 - 0.039 13.8 0.0 0.098 12.5 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Choline_transpo PF04515.12 KXL44699.1 - 5.7e-81 272.3 20.4 6.4e-81 272.1 20.4 1.0 1 0 0 1 1 1 1 Plasma-membrane choline transporter DUF2207 PF09972.9 KXL44700.1 - 0.0094 14.8 0.0 0.011 14.6 0.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) RAMP4 PF06624.12 KXL44700.1 - 0.048 13.7 0.8 3 8.0 0.0 2.3 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 Pex14_N PF04695.13 KXL44700.1 - 0.068 13.8 0.4 0.1 13.2 0.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MgtC PF02308.16 KXL44700.1 - 0.18 12.2 3.6 0.25 11.7 3.6 1.2 1 0 0 1 1 1 0 MgtC family HSP70 PF00012.20 KXL44701.1 - 3.1e-267 887.6 14.8 3.6e-267 887.4 14.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXL44701.1 - 5.9e-15 54.9 2.0 2.1e-13 49.8 0.5 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 KXL44701.1 - 0.0045 16.7 0.0 0.0095 15.7 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 KXL44701.1 - 0.0096 16.3 4.9 0.92 10.0 0.3 3.8 3 1 0 3 3 3 2 Cell division protein FtsA Toxin-deaminase PF14424.6 KXL44701.1 - 0.15 12.2 2.7 0.19 11.8 0.0 2.3 2 0 0 2 2 2 0 The BURPS668_1122 family of deaminases DUF948 PF06103.11 KXL44701.1 - 0.87 9.9 3.8 3.2 8.1 0.9 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4192 PF13830.6 KXL44701.1 - 9.4 6.2 6.5 27 4.7 5.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) EAP30 PF04157.16 KXL44702.1 - 6e-39 133.7 0.0 8.3e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 KXL44702.1 - 1.2e-24 86.3 0.0 1.8e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Vps36-NZF-N PF16988.5 KXL44702.1 - 2.8e-21 74.7 0.8 2.8e-21 74.7 0.8 2.7 2 1 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-RanBP PF00641.18 KXL44702.1 - 1e-05 24.7 6.5 0.00057 19.1 1.6 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.15 KXL44702.1 - 2.1e-05 24.5 1.6 0.0087 16.1 0.0 2.7 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger DZR PF12773.7 KXL44702.1 - 0.0069 16.4 6.4 0.0069 16.4 1.2 2.5 2 1 0 2 2 2 1 Double zinc ribbon GRAM PF02893.20 KXL44702.1 - 0.0094 15.8 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 1 GRAM domain DUF35_N PF12172.8 KXL44702.1 - 0.018 14.9 2.4 0.049 13.5 2.4 1.7 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) EutK_C PF16365.5 KXL44702.1 - 0.019 15.0 0.5 0.048 13.7 0.1 1.8 2 0 0 2 2 2 0 Ethanolamine utilization protein EutK C-terminus Rubredoxin PF00301.20 KXL44702.1 - 2.3 8.3 7.2 2.2 8.4 0.4 3.4 3 1 1 4 4 4 0 Rubredoxin SAC3_GANP PF03399.16 KXL44703.1 - 1.4e-24 87.0 1.7 1e-22 80.9 1.7 2.2 1 1 0 1 1 1 1 SAC3/GANP family XRN1_D1 PF18332.1 KXL44705.1 - 4.5e-43 147.2 0.0 5.8e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 KXL44705.1 - 1e-31 109.0 0.0 1.7e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 KXL44706.1 - 1.9e-24 85.5 0.4 3.5e-24 84.7 0.4 1.5 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 KXL44706.1 - 2.9e-07 30.5 0.5 6.1e-07 29.4 0.1 1.8 3 0 0 3 3 3 1 Exoribonuclease 1 Domain-3 XRN_N PF03159.18 KXL44707.1 - 3.2e-90 301.8 0.0 3.6e-90 301.6 0.0 1.0 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus DUF3576 PF12100.8 KXL44708.1 - 0.089 12.9 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3576) KASH_CCD PF14662.6 KXL44710.1 - 0.018 14.9 6.1 0.023 14.6 6.1 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF3450 PF11932.8 KXL44710.1 - 0.19 11.0 4.8 0.23 10.7 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) LppA PF16708.5 KXL44710.1 - 0.21 11.5 2.0 1.5 8.7 0.0 2.1 1 1 1 2 2 2 0 Lipoprotein confined to pathogenic Mycobacterium E2F_CC-MB PF16421.5 KXL44710.1 - 0.54 10.6 3.9 1.4 9.3 4.0 1.7 1 1 0 1 1 1 0 E2F transcription factor CC-MB domain Atg14 PF10186.9 KXL44710.1 - 0.93 8.5 6.0 1.1 8.3 6.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4140 PF13600.6 KXL44710.1 - 6.3 7.3 9.1 1 9.8 4.1 2.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) APG6_N PF17675.1 KXL44710.1 - 8.1 7.0 14.9 24 5.4 14.8 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region PSP1 PF04468.12 KXL44714.1 - 2.6e-26 91.7 2.1 5e-26 90.8 2.1 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Thiolase_N PF00108.23 KXL44715.1 - 7.5e-92 307.4 1.7 7.5e-92 307.4 1.7 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXL44715.1 - 1.6e-37 127.9 1.1 1.6e-37 127.9 1.1 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXL44715.1 - 0.00013 21.7 0.6 0.00013 21.7 0.6 2.2 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KXL44715.1 - 0.0052 16.6 0.8 0.66 9.9 0.2 2.8 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SMN PF06003.12 KXL44719.1 - 0.3 10.3 6.3 0.44 9.8 6.3 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Zip PF02535.22 KXL44720.1 - 1.2e-58 199.0 0.9 1.3e-58 198.8 0.9 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter UNC-50 PF05216.13 KXL44720.1 - 0.0068 16.0 0.8 0.082 12.5 0.3 2.2 2 0 0 2 2 2 1 UNC-50 family EAF PF09816.9 KXL44721.1 - 0.00024 21.5 0.0 0.00051 20.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor EPSP_synthase PF00275.20 KXL44722.1 - 6.7e-119 397.3 0.0 1e-118 396.7 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 KXL44722.1 - 2.8e-95 318.5 0.0 4.8e-95 317.7 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 KXL44722.1 - 1.9e-55 188.7 0.0 3.7e-55 187.7 0.0 1.5 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KXL44722.1 - 2.8e-33 115.3 0.0 5.6e-32 111.0 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 KXL44722.1 - 5.1e-23 81.1 0.0 9.6e-23 80.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KXL44722.1 - 2.5e-08 33.6 0.1 5.9e-08 32.3 0.1 1.7 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KXL44722.1 - 0.00024 21.2 0.0 0.00048 20.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.6 KXL44722.1 - 0.0003 20.6 0.1 0.00084 19.1 0.1 1.7 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Mito_fiss_Elm1 PF06258.11 KXL44722.1 - 0.19 10.8 0.2 2.6 7.1 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial fission ELM1 XFP_N PF09364.10 KXL44724.1 - 3.4e-166 552.5 0.0 4.8e-166 552.1 0.0 1.2 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 KXL44724.1 - 5.3e-81 270.9 0.0 8.4e-81 270.3 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 KXL44724.1 - 1.7e-74 249.4 0.1 2.1e-72 242.6 0.1 2.3 1 1 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase BTRD1 PF17660.1 KXL44724.1 - 0.034 14.0 0.1 10 6.0 0.0 3.2 3 0 0 3 3 3 0 Bacterial tandem repeat domain 1 TPP_enzyme_C PF02775.21 KXL44724.1 - 0.16 11.7 0.1 1 9.1 0.1 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Esterase_phd PF10503.9 KXL44726.1 - 4.4e-06 26.3 0.4 9.4e-06 25.3 0.4 1.5 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KXL44726.1 - 0.0014 18.1 0.5 0.0032 17.0 0.3 1.6 1 1 1 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 KXL44726.1 - 0.015 14.0 0.2 0.11 11.2 0.0 1.9 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 KXL44726.1 - 0.027 13.8 0.0 0.052 12.8 0.0 1.5 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Transp_cyt_pur PF02133.15 KXL44728.1 - 5.8e-94 315.4 38.8 6.8e-94 315.1 38.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Epimerase PF01370.21 KXL44729.1 - 0.00056 19.5 0.0 0.0009 18.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding PF00501.28 KXL44730.1 - 5.7e-74 249.2 0.0 7e-74 248.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KXL44730.1 - 1.3e-19 69.8 0.7 4.7e-19 68.1 0.7 2.0 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KXL44730.1 - 1.3e-15 58.1 0.0 2.5e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Apolipoprotein PF01442.18 KXL44731.1 - 0.001 19.0 8.2 0.001 19.0 8.2 11.4 4 3 5 9 9 9 5 Apolipoprotein A1/A4/E domain Tup_N PF08581.10 KXL44731.1 - 0.0077 16.5 0.8 0.0077 16.5 0.8 12.9 10 5 5 15 15 15 3 Tup N-terminal F_actin_bind PF08919.10 KXL44731.1 - 0.082 13.0 6.9 2.1 8.5 0.0 6.0 5 0 0 5 5 5 0 F-actin binding HEPN_Swt1 PF18731.1 KXL44731.1 - 0.76 10.1 6.0 0.84 10.0 0.0 4.2 4 0 0 4 4 4 0 Swt1-like HEPN Ribosomal_L27e PF01777.18 KXL44732.1 - 4e-37 126.4 3.7 5.8e-37 125.9 3.7 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 KXL44732.1 - 0.046 13.7 1.6 0.089 12.8 0.4 2.1 2 0 0 2 2 2 0 KOW motif Tyrosinase PF00264.20 KXL44734.1 - 7.7e-50 170.2 4.2 1.4e-49 169.3 4.2 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KXL44734.1 - 5.3e-31 107.8 0.0 8.4e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Tyosinase C-terminal domain AA_permease_2 PF13520.6 KXL44735.1 - 3.1e-23 82.3 52.3 2.7e-12 46.3 19.4 3.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 KXL44735.1 - 3.9e-10 38.9 37.8 1.4e-06 27.2 11.2 3.1 2 1 1 3 3 3 3 Amino acid permease ER_lumen_recept PF00810.18 KXL44736.1 - 4.3e-50 170.4 4.9 1.4e-49 168.7 4.9 1.9 1 1 0 1 1 1 1 ER lumen protein retaining receptor PHA_synth_III_E PF09712.10 KXL44736.1 - 0.0043 16.2 0.3 0.0043 16.2 0.3 2.2 2 0 0 2 2 2 1 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) DUF4449 PF14613.6 KXL44736.1 - 0.008 16.3 0.1 0.008 16.3 0.1 3.5 4 0 0 4 4 4 1 Protein of unknown function (DUF4449) PQ-loop PF04193.14 KXL44736.1 - 0.032 14.0 2.7 7.4 6.4 0.0 2.8 2 0 0 2 2 2 0 PQ loop repeat UvrD_C PF13361.6 KXL44736.1 - 0.091 12.1 1.2 0.36 10.2 1.2 1.9 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF1002 PF06207.11 KXL44736.1 - 0.76 9.3 3.0 2.5 7.6 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1002) DUF445 PF04286.12 KXL44736.1 - 0.87 9.3 11.4 0.18 11.6 6.2 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF445) FAST_2 PF08368.12 KXL44736.1 - 1.3 9.8 3.6 25 5.7 0.1 3.3 2 1 1 3 3 3 0 FAST kinase-like protein, subdomain 2 SKA2 PF16740.5 KXL44736.1 - 1.3 8.8 7.1 11 5.8 0.7 3.7 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 RsbRD_N PF14361.6 KXL44736.1 - 1.4 9.7 7.8 0.61 10.8 0.3 3.8 3 1 0 3 3 3 0 RsbT co-antagonist protein rsbRD N-terminal domain Peptidase_M24 PF00557.24 KXL44737.1 - 2e-08 34.2 0.1 7e-08 32.4 0.1 1.7 1 1 0 1 1 1 1 Metallopeptidase family M24 ANAPC15 PF15243.6 KXL44737.1 - 0.22 12.0 8.9 0.5 10.8 8.9 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Ribosomal_60s PF00428.19 KXL44737.1 - 0.26 11.9 4.6 1.8 9.2 5.2 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Pox_Ag35 PF03286.14 KXL44737.1 - 0.55 10.0 11.5 1.1 9.0 11.5 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PBP1_TM PF14812.6 KXL44737.1 - 0.59 10.5 12.0 1.4 9.3 12.0 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.11 KXL44737.1 - 1.3 9.0 11.6 5.9 6.9 9.3 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal FAM176 PF14851.6 KXL44737.1 - 3.6 7.2 8.0 6.3 6.5 8.0 1.4 1 0 0 1 1 1 0 FAM176 family PHD PF00628.29 KXL44738.1 - 9.2e-17 60.7 18.8 5.1e-10 39.1 6.1 2.4 2 0 0 2 2 2 2 PHD-finger zf-HC5HC2H PF13771.6 KXL44738.1 - 0.00072 19.8 6.4 0.44 10.8 1.8 2.4 2 0 0 2 2 2 2 PHD-like zinc-binding domain C1_1 PF00130.22 KXL44738.1 - 0.0015 18.4 11.4 0.013 15.4 2.2 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H_2 PF13832.6 KXL44738.1 - 0.018 15.2 3.1 0.95 9.7 0.3 2.4 2 0 0 2 2 2 0 PHD-zinc-finger like domain zf-PHD-like PF15446.6 KXL44738.1 - 0.076 12.6 9.7 1.4 8.5 2.0 2.5 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Zf_RING PF16744.5 KXL44738.1 - 0.22 11.7 4.9 7.3 6.8 0.4 2.5 2 0 0 2 2 2 0 KIAA1045 RING finger Prok-RING_1 PF14446.6 KXL44738.1 - 0.8 9.7 12.8 0.021 14.7 2.8 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zinc_ribbon_2 PF13240.6 KXL44738.1 - 2.2 8.1 7.8 1 9.1 0.4 3.1 3 0 0 3 3 3 0 zinc-ribbon domain C1_2 PF03107.16 KXL44738.1 - 4.4 7.7 21.7 0.022 15.0 5.6 2.8 3 0 0 3 3 3 0 C1 domain PRP3 PF08572.10 KXL44739.1 - 1.3e-66 224.6 8.5 1.3e-66 224.6 8.5 2.3 2 1 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KXL44739.1 - 1.2e-46 158.5 0.0 3e-46 157.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) GET2 PF08690.10 KXL44739.1 - 4.5 6.9 19.5 0.078 12.6 5.7 2.3 2 0 0 2 2 2 0 GET complex subunit GET2 PRP1_N PF06424.12 KXL44740.1 - 8.8e-52 175.5 7.7 2.2e-51 174.1 7.7 1.7 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_19 PF14559.6 KXL44740.1 - 7e-21 74.5 15.8 1.3e-06 28.9 0.4 9.8 6 3 4 11 11 10 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXL44740.1 - 8.1e-20 69.8 39.3 0.00034 21.2 0.1 13.7 7 3 8 15 15 13 8 Tetratricopeptide repeat TPR_2 PF07719.17 KXL44740.1 - 2.6e-09 36.5 13.8 0.97 9.7 0.0 9.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXL44740.1 - 3.7e-09 37.1 14.7 0.0044 17.7 0.0 6.7 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXL44740.1 - 1.4e-08 34.5 0.3 0.68 10.4 0.0 9.0 11 1 0 11 11 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXL44740.1 - 2.5e-08 33.5 0.0 3.7 8.0 0.0 7.9 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXL44740.1 - 3.4e-06 27.1 8.6 0.0052 16.9 0.0 5.3 5 1 0 5 5 5 2 Tetratricopeptide repeat Suf PF05843.14 KXL44740.1 - 3.4e-05 24.0 3.0 0.19 11.6 0.0 4.3 4 1 0 4 4 4 2 Suppressor of forked protein (Suf) NARP1 PF12569.8 KXL44740.1 - 3.8e-05 22.8 7.9 0.94 8.3 0.0 6.2 4 1 3 7 7 7 2 NMDA receptor-regulated protein 1 TPR_1 PF00515.28 KXL44740.1 - 7.7e-05 22.3 0.1 0.58 10.1 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXL44740.1 - 0.0098 15.6 0.5 12 5.7 0.0 4.7 4 0 0 4 4 4 1 TPR repeat TPR_15 PF13429.6 KXL44740.1 - 0.4 9.8 38.0 0.019 14.2 4.8 5.9 3 2 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXL44740.1 - 0.5 11.1 11.6 18 6.2 0.0 7.4 9 0 0 9 9 8 0 Tetratricopeptide repeat AA_permease_2 PF13520.6 KXL44741.1 - 3e-61 207.5 53.3 3.8e-61 207.2 53.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXL44741.1 - 1.3e-15 57.0 44.5 1.7e-15 56.6 44.5 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1980 PF09323.10 KXL44741.1 - 0.49 10.3 4.7 16 5.4 0.6 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) zf-Mss51 PF13824.6 KXL44742.1 - 2.3e-26 91.6 7.3 4.5e-26 90.7 7.3 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KXL44742.1 - 0.012 15.7 2.3 0.012 15.6 0.3 2.0 2 0 0 2 2 2 0 MYND finger MMS1_N PF10433.9 KXL44743.1 - 3.1e-101 339.4 0.0 4.1e-101 339.0 0.0 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KXL44743.1 - 4.6e-88 295.6 0.0 7.8e-88 294.9 0.0 1.4 1 0 0 1 1 1 1 CPSF A subunit region FAM199X PF15814.5 KXL44745.1 - 0.0046 16.1 1.3 0.009 15.1 1.3 1.5 1 0 0 1 1 1 1 Protein family FAM199X LSM PF01423.22 KXL44746.1 - 2.2e-20 72.1 0.3 3e-20 71.7 0.3 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXL44746.1 - 0.074 13.2 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF3145 PF11343.8 KXL44747.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3145) Zn_clus PF00172.18 KXL44747.1 - 0.43 10.8 12.7 1.2 9.3 12.7 1.8 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KXL44748.1 - 0.0093 16.4 3.3 0.0093 16.4 3.3 2.6 2 1 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXL44748.1 - 4.8 8.3 7.3 0.89 10.6 1.3 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger Choline_kinase PF01633.20 KXL44749.1 - 9.3e-63 211.6 0.0 1.7e-62 210.8 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 KXL44749.1 - 3.1e-17 62.0 0.0 1.3e-16 60.0 0.0 2.0 2 0 0 2 2 2 1 Choline kinase N terminus APH PF01636.23 KXL44749.1 - 1.5e-06 28.3 2.1 3e-06 27.3 2.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family FAD_binding_4 PF01565.23 KXL44750.1 - 7.9e-27 93.7 0.0 1.3e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 KXL44750.1 - 3.4e-14 53.1 0.0 5.7e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain DEAD PF00270.29 KXL44751.1 - 1.5e-46 158.4 0.0 2.5e-46 157.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXL44751.1 - 9.5e-27 93.5 0.4 2.9e-26 92.0 0.1 2.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UTP25 PF06862.12 KXL44751.1 - 4.8e-05 22.3 1.3 0.00062 18.7 0.0 2.8 3 1 1 4 4 4 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 4HBT_3 PF13622.6 KXL44752.1 - 1.9e-84 283.8 0.1 2.4e-84 283.5 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KXL44752.1 - 3.5e-28 98.1 0.0 2.9e-12 46.6 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase HMGL-like PF00682.19 KXL44753.1 - 2.2e-76 256.9 0.0 9.4e-76 254.8 0.0 1.8 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.10 KXL44753.1 - 3e-21 75.7 0.0 6.8e-21 74.6 0.0 1.6 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain Sigma_reg_N PF13800.6 KXL44753.1 - 0.13 12.6 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal IlvN PF07991.12 KXL44754.1 - 6.3e-46 156.0 0.0 1e-45 155.3 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KXL44754.1 - 6.4e-40 136.8 0.7 1.2e-39 135.9 0.7 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.15 KXL44754.1 - 0.014 15.6 0.0 0.026 14.7 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KXL44754.1 - 0.051 14.2 0.0 0.12 12.9 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent CotJA PF11007.8 KXL44754.1 - 0.18 11.6 0.0 0.58 10.0 0.0 1.8 1 0 0 1 1 1 0 Spore coat associated protein JA (CotJA) PRELI PF04707.14 KXL44755.1 - 1.4e-19 70.5 0.1 1.5e-17 63.9 0.1 2.4 2 1 0 2 2 2 2 PRELI-like family tRNA-synt_1b PF00579.25 KXL44756.1 - 1.9e-18 66.8 0.0 2.1e-12 47.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) Pro_isomerase PF00160.21 KXL44757.1 - 3.1e-47 160.8 0.2 4.6e-47 160.2 0.2 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 KXL44757.1 - 3e-10 39.4 2.6 0.0018 18.2 0.3 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXL44757.1 - 4.4e-09 35.8 2.0 0.0027 17.5 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXL44757.1 - 7.1e-06 25.8 2.4 0.061 13.6 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXL44757.1 - 0.00013 22.2 2.5 0.0064 16.8 0.5 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXL44757.1 - 0.00046 19.8 0.5 1.4 8.7 0.1 3.2 3 0 0 3 3 3 2 TPR repeat TPR_14 PF13428.6 KXL44757.1 - 0.0023 18.6 4.5 0.1 13.5 0.4 3.7 3 1 0 4 4 4 1 Tetratricopeptide repeat MIT PF04212.18 KXL44757.1 - 0.0054 16.8 3.3 1.8 8.7 0.0 2.5 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain DUF3856 PF12968.7 KXL44757.1 - 0.028 14.5 1.1 0.15 12.1 0.9 2.3 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) TPR_10 PF13374.6 KXL44757.1 - 0.077 12.9 0.4 1.9 8.5 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXL44757.1 - 0.18 12.5 9.9 0.15 12.7 2.1 3.5 4 1 0 4 4 3 0 Tetratricopeptide repeat DUF5113 PF17140.4 KXL44757.1 - 0.18 11.6 0.0 0.39 10.5 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5113) TPR_6 PF13174.6 KXL44757.1 - 2.4 9.0 6.5 4.5 8.1 0.3 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF4536 PF15055.6 KXL44758.1 - 1.2e-07 31.8 1.2 1.8e-06 28.1 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4536) Ribosomal_L37ae PF01780.19 KXL44758.1 - 0.045 13.8 0.0 0.64 10.1 0.0 2.1 2 0 0 2 2 2 0 Ribosomal L37ae protein family Glyco_hydro_28 PF00295.17 KXL44759.1 - 8.8e-116 386.5 17.5 1.3e-115 385.9 17.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 MOSC PF03473.17 KXL44760.1 - 2.8e-29 101.8 0.0 4.6e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KXL44760.1 - 6e-20 71.3 0.0 1e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain His_Phos_1 PF00300.22 KXL44761.1 - 1.8e-36 125.6 0.0 2.4e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SQHop_cyclase_C PF13243.6 KXL44762.1 - 1.8e-44 152.2 0.4 1e-41 143.1 0.4 3.4 2 2 1 3 3 3 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KXL44762.1 - 9.2e-38 130.0 4.1 2e-31 109.2 0.4 3.3 2 1 1 3 3 3 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 KXL44762.1 - 1.3e-21 76.0 11.5 6.6e-09 35.4 0.5 4.8 5 1 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 KXL44762.1 - 0.00063 18.9 0.1 0.025 13.6 0.0 3.1 2 1 1 3 3 3 1 A-macroglobulin TED domain WD40 PF00400.32 KXL44763.1 - 1.6e-21 76.2 4.0 0.00015 22.5 0.1 6.8 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL44763.1 - 2.2e-14 53.5 0.0 0.15 12.4 0.0 5.6 2 1 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXL44763.1 - 6.2e-07 28.7 0.2 0.00046 19.3 0.0 3.1 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KXL44763.1 - 0.00026 20.4 0.2 4.2 6.6 0.0 3.8 2 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.6 KXL44763.1 - 0.00054 19.6 0.1 0.024 14.2 0.0 2.5 2 1 0 2 2 2 1 PQQ-like domain IKI3 PF04762.12 KXL44763.1 - 0.0048 15.0 0.0 0.1 10.6 0.0 2.5 2 2 0 2 2 2 1 IKI3 family CLTH PF10607.9 KXL44763.1 - 0.063 13.2 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain CAF1C_H4-bd PF12265.8 KXL44763.1 - 0.18 12.0 0.3 0.74 10.1 0.0 2.1 2 0 0 2 2 2 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex PLU-1 PF08429.11 KXL44764.1 - 1.1e-106 356.9 21.7 4.2e-103 345.1 19.9 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 KXL44764.1 - 4.1e-43 146.4 1.6 1e-42 145.1 0.2 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase ARID PF01388.21 KXL44764.1 - 2.7e-21 76.0 0.1 8.5e-21 74.4 0.1 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 KXL44764.1 - 8.9e-15 54.4 3.0 2.3e-14 53.1 3.0 1.8 1 0 0 1 1 1 1 jmjN domain PHD PF00628.29 KXL44764.1 - 9.6e-15 54.2 40.1 2e-08 34.0 15.2 3.1 3 0 0 3 3 3 2 PHD-finger zf-C5HC2 PF02928.16 KXL44764.1 - 7.2e-12 45.5 8.3 7.2e-12 45.5 8.3 2.6 3 0 0 3 3 3 1 C5HC2 zinc finger zf-PHD-like PF15446.6 KXL44764.1 - 0.016 14.8 11.0 0.21 11.2 3.8 2.7 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_4 PF16866.5 KXL44764.1 - 6.5 6.9 25.4 0.1 12.7 5.1 2.7 2 0 0 2 2 2 0 PHD-finger GIY-YIG PF01541.24 KXL44765.1 - 1.9e-14 53.7 0.0 3.3e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.8 KXL44765.1 - 8.2e-05 22.7 1.9 0.00017 21.7 1.9 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-HC5HC2H PF13771.6 KXL44765.1 - 0.0015 18.7 0.3 0.003 17.8 0.3 1.4 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KXL44765.1 - 0.013 15.6 0.2 0.026 14.7 0.2 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain C1_2 PF03107.16 KXL44765.1 - 0.025 14.9 2.1 0.026 14.8 0.3 1.9 2 0 0 2 2 2 0 C1 domain PHD PF00628.29 KXL44765.1 - 0.11 12.5 2.1 0.21 11.5 2.1 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 KXL44765.1 - 0.73 10.2 2.9 2.3 8.6 2.9 1.9 1 1 0 1 1 1 0 RING-like domain MTHFR PF02219.17 KXL44766.1 - 1.3e-99 333.1 0.0 2.2e-99 332.4 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase PSI PF01437.25 KXL44767.1 - 2.6e-05 24.7 9.2 4.3e-05 24.0 9.2 1.4 1 0 0 1 1 1 1 Plexin repeat NUDIX PF00293.28 KXL44769.1 - 8.5e-20 71.1 0.1 1.2e-19 70.6 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KXL44769.1 - 9e-07 28.9 0.0 0.00025 21.0 0.0 2.1 2 0 0 2 2 2 2 NUDIX domain DUF1275 PF06912.11 KXL44770.1 - 2.4e-39 135.3 17.6 2.7e-39 135.1 17.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) ATPase_gene1 PF09527.10 KXL44770.1 - 0.15 12.2 0.4 0.15 12.2 0.4 2.7 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter DUF4131 PF13567.6 KXL44770.1 - 0.22 11.1 9.5 0.71 9.5 4.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) MFS_1 PF07690.16 KXL44771.1 - 5.3e-27 94.7 50.1 2.1e-26 92.7 25.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PTR2 PF00854.21 KXL44771.1 - 0.00015 20.8 0.1 0.0012 17.8 0.0 2.1 2 0 0 2 2 2 1 POT family DUF3382 PF11862.8 KXL44771.1 - 4.6 7.6 11.4 0.62 10.4 0.6 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) Sulfotransfer_4 PF17784.1 KXL44772.1 - 1.7e-31 109.8 0.0 1.8e-31 109.6 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain FAD-oxidase_C PF02913.19 KXL44773.1 - 2.2e-61 207.6 0.0 5.4e-61 206.4 0.0 1.6 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KXL44773.1 - 6.1e-37 126.5 0.2 1.1e-36 125.7 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Tudor_3 PF18115.1 KXL44774.1 - 4.3e-20 71.3 0.4 1.9e-19 69.2 0.2 2.2 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain Rad9_Rad53_bind PF08605.10 KXL44774.1 - 8.4e-10 38.9 0.1 1.6e-09 38.0 0.1 1.5 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.26 KXL44774.1 - 8.7e-08 32.4 0.0 6.3e-05 23.3 0.0 3.5 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KXL44774.1 - 0.026 14.9 0.0 0.21 12.0 0.0 2.5 3 0 0 3 3 3 0 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 KXL44774.1 - 0.031 14.2 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 KXL44774.1 - 0.042 13.9 0.0 12 6.1 0.0 2.6 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain CoA_transf_3 PF02515.17 KXL44775.1 - 8e-64 216.1 0.0 1e-63 215.7 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III DUF1967 PF09269.11 KXL44777.1 - 0.11 12.4 0.2 0.29 11.1 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1967) tRNA-synt_1e PF01406.19 KXL44778.1 - 1.9e-113 378.8 0.0 3.4e-113 378.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KXL44778.1 - 2.2e-06 26.7 0.5 0.0085 14.9 0.1 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1d PF00750.19 KXL44778.1 - 0.0042 16.1 0.0 0.15 11.0 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (R) DALR_2 PF09190.11 KXL44778.1 - 0.0049 17.3 0.0 0.0049 17.3 0.0 2.0 2 0 0 2 2 2 1 DALR domain DnaT PF17948.1 KXL44778.1 - 0.085 12.6 0.0 0.27 11.0 0.0 1.9 1 0 0 1 1 1 0 DnaT DNA-binding domain DUF2330 PF10092.9 KXL44778.1 - 0.094 11.8 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2330) Gtr1_RagA PF04670.12 KXL44779.1 - 1.6e-86 289.5 0.0 2e-86 289.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KXL44779.1 - 1.5e-08 34.9 0.0 3.5e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXL44779.1 - 7.3e-08 32.1 0.0 2.1e-07 30.6 0.0 1.7 1 1 1 2 2 2 1 ADP-ribosylation factor family Ras PF00071.22 KXL44779.1 - 2.7e-07 30.3 0.0 4.4e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KXL44779.1 - 1e-06 28.8 0.0 2.1e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXL44779.1 - 0.00049 20.0 0.2 0.12 12.2 0.0 2.6 3 0 0 3 3 3 1 RsgA GTPase G-alpha PF00503.20 KXL44779.1 - 0.0029 16.8 3.4 0.32 10.1 0.0 2.9 2 1 1 3 3 3 2 G-protein alpha subunit DUF815 PF05673.13 KXL44779.1 - 0.0044 16.2 0.0 0.0077 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 KXL44779.1 - 0.011 16.3 0.1 0.038 14.5 0.0 1.8 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 KXL44779.1 - 0.02 14.6 0.3 0.19 11.5 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KXL44779.1 - 0.021 15.2 0.0 0.042 14.2 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain TniB PF05621.11 KXL44779.1 - 0.062 12.7 0.8 2.4 7.5 0.2 2.6 2 1 0 2 2 2 0 Bacterial TniB protein SWI-SNF_Ssr4 PF08549.10 KXL44782.1 - 1.2e-168 563.1 13.4 1.6e-168 562.6 13.4 1.3 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) RRF PF01765.19 KXL44782.1 - 0.32 11.0 1.9 0.81 9.6 1.1 2.0 2 0 0 2 2 2 0 Ribosome recycling factor HIP1_clath_bdg PF16515.5 KXL44782.1 - 1.1 9.9 3.9 0.46 11.1 0.5 2.1 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Ras PF00071.22 KXL44783.1 - 9e-53 178.2 0.4 5.2e-52 175.7 0.4 1.8 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KXL44783.1 - 3.1e-19 69.4 0.0 1.9e-17 63.6 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXL44783.1 - 2.7e-05 23.7 0.0 0.00054 19.5 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXL44783.1 - 0.0074 15.8 0.1 1.8 8.0 0.1 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KXL44783.1 - 0.022 14.7 0.0 5.8 6.8 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Septin PF00735.18 KXL44783.1 - 0.062 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Septin MMR_HSR1 PF01926.23 KXL44783.1 - 0.063 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.18 KXL44783.1 - 0.086 12.4 0.0 1 8.8 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_25 PF13481.6 KXL44783.1 - 0.17 11.4 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXL44783.1 - 0.18 12.2 0.1 0.32 11.4 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain rve PF00665.26 KXL44784.1 - 0.13 12.4 0.1 0.17 12.1 0.1 1.1 1 0 0 1 1 1 0 Integrase core domain Far-17a_AIG1 PF04750.14 KXL44785.1 - 7e-54 182.2 7.9 8.1e-54 182.0 7.9 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein EHD_N PF16880.5 KXL44785.1 - 0.17 11.8 0.4 0.31 11.0 0.4 1.4 1 0 0 1 1 1 0 N-terminal EH-domain containing protein DDE_1 PF03184.19 KXL44786.1 - 0.0019 17.9 0.0 0.002 17.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease TRP PF06011.12 KXL44787.1 - 2.1e-138 461.7 20.1 2.5e-138 461.4 20.1 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KXL44787.1 - 2e-36 125.4 1.5 4e-36 124.4 1.5 1.5 1 0 0 1 1 1 1 ML-like domain HemY_N PF07219.13 KXL44787.1 - 0.0017 18.5 7.8 0.34 11.1 3.0 3.6 3 0 0 3 3 3 1 HemY protein N-terminus Hydantoinase_A PF01968.18 KXL44787.1 - 0.024 13.9 0.1 0.046 13.0 0.1 1.3 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase DUF2457 PF10446.9 KXL44788.1 - 0.001 18.4 16.8 0.0015 17.8 16.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) YL1 PF05764.13 KXL44788.1 - 0.0022 18.1 1.5 0.0033 17.6 1.5 1.3 1 0 0 1 1 1 1 YL1 nuclear protein TIMELESS_C PF05029.13 KXL44788.1 - 0.0068 15.6 1.0 0.0089 15.2 1.0 1.2 1 0 0 1 1 1 1 Timeless protein C terminal region SDA1 PF05285.12 KXL44788.1 - 0.021 14.3 4.3 0.027 13.9 4.3 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 KXL44788.1 - 0.31 9.3 7.8 0.4 8.9 7.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KXL44788.1 - 0.69 8.0 8.3 0.94 7.6 8.3 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 KXL44788.1 - 1.1 8.6 16.7 1.8 7.8 16.7 1.3 1 0 0 1 1 1 0 NOA36 protein Sporozoite_P67 PF05642.11 KXL44788.1 - 1.3 7.0 5.9 2 6.4 5.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PBP1_TM PF14812.6 KXL44788.1 - 2.2 8.7 15.7 6.6 7.2 15.7 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 KXL44788.1 - 2.6 7.7 5.9 4.8 6.8 5.9 1.5 1 0 0 1 1 1 0 FAM176 family PGA2 PF07543.12 KXL44788.1 - 3.5 7.6 8.5 0.87 9.6 5.1 1.7 2 0 0 2 2 2 0 Protein trafficking PGA2 TFIIF_alpha PF05793.12 KXL44788.1 - 4 5.9 12.9 6.7 5.2 12.9 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.10 KXL44788.1 - 5.5 6.2 13.3 8.6 5.6 13.3 1.2 1 0 0 1 1 1 0 BUD22 DUF4611 PF15387.6 KXL44788.1 - 8.8 6.6 12.0 23 5.3 12.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Med4 PF10018.9 KXL44789.1 - 3.1e-29 102.1 4.3 4.3e-29 101.6 4.3 1.1 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF4665 PF15679.5 KXL44789.1 - 0.1 13.3 0.5 0.67 10.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4665) Lsr2 PF11774.8 KXL44789.1 - 0.62 10.2 5.2 0.49 10.6 1.2 2.1 2 0 0 2 2 2 0 Lsr2 Peptidase_C2 PF00648.21 KXL44791.1 - 7.3e-63 212.4 1.1 1.3e-41 142.6 0.1 2.4 2 0 0 2 2 2 2 Calpain family cysteine protease DUF4662 PF15578.6 KXL44791.1 - 1.6 8.5 13.0 2.8 7.6 13.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) adh_short PF00106.25 KXL44792.1 - 7.6e-40 136.5 0.0 3.7e-39 134.2 0.0 2.0 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL44792.1 - 2.6e-37 128.6 0.0 8.4e-36 123.7 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL44792.1 - 2.8e-06 27.4 0.1 5.5e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXL44792.1 - 0.036 14.0 0.0 0.12 12.2 0.0 1.8 2 1 0 2 2 2 0 NAD(P)H-binding ADH_zinc_N PF00107.26 KXL44792.1 - 0.064 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 3Beta_HSD PF01073.19 KXL44792.1 - 0.16 10.9 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AdoHcyase_NAD PF00670.21 KXL44792.1 - 1.1 9.4 3.3 1.1 9.2 1.8 1.7 1 1 1 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Ring_hydroxyl_A PF00848.19 KXL44793.1 - 7.5e-25 88.1 4.5 7.8e-12 45.6 0.1 2.2 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 KXL44793.1 - 1.5e-12 47.3 0.0 3e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain CxC2 PF18803.1 KXL44793.1 - 0.022 14.9 0.0 0.053 13.7 0.0 1.6 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases GCV_T PF01571.21 KXL44794.1 - 5.1e-59 199.7 0.0 7.9e-59 199.1 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 KXL44794.1 - 8.3e-42 144.0 0.2 8.3e-42 144.0 0.2 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase GCV_T_C PF08669.11 KXL44794.1 - 2.2e-18 65.9 0.6 5.6e-18 64.6 0.1 2.1 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain FAO_M PF16350.5 KXL44794.1 - 3.2e-18 65.8 0.0 5.8e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain Pyr_redox_2 PF07992.14 KXL44794.1 - 4.3e-06 26.2 0.2 0.085 12.1 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 KXL44794.1 - 0.00014 21.3 0.1 0.00028 20.3 0.1 1.4 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.18 KXL44794.1 - 0.00091 19.5 0.4 0.0029 17.9 0.2 2.0 2 0 0 2 2 2 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 KXL44794.1 - 0.00091 19.5 0.1 0.11 12.7 0.1 2.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain FAD_binding_2 PF00890.24 KXL44794.1 - 0.00091 18.4 0.1 0.0018 17.4 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KXL44794.1 - 0.0013 18.8 0.3 0.42 10.6 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 KXL44794.1 - 0.004 17.2 0.1 0.0078 16.3 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SoxG PF04268.12 KXL44794.1 - 0.05 13.8 0.0 0.77 9.9 0.0 2.3 2 0 0 2 2 2 0 Sarcosine oxidase, gamma subunit family Pyr_redox PF00070.27 KXL44794.1 - 0.054 14.0 0.1 0.054 14.0 0.1 2.7 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXL44794.1 - 0.11 12.7 0.0 0.36 11.1 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KXL44794.1 - 0.2 10.9 0.4 2.3 7.4 0.2 2.3 3 0 0 3 3 3 0 FAD binding domain AlaDh_PNT_C PF01262.21 KXL44794.1 - 0.34 10.2 2.8 0.15 11.3 0.2 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KXL44795.1 - 5.2e-35 121.7 0.1 6.3e-35 121.4 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXL44795.1 - 1.8e-07 31.3 0.2 0.0058 16.6 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXL44795.1 - 0.00016 21.8 0.0 0.00072 19.7 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXL44795.1 - 0.00016 21.0 0.1 0.49 9.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXL44795.1 - 0.00024 20.5 0.1 0.63 9.2 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXL44795.1 - 0.00029 20.1 0.0 0.0013 17.9 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 KXL44795.1 - 0.019 14.2 0.0 0.039 13.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 KXL44795.1 - 0.022 13.6 0.1 1.6 7.5 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase TrkA_N PF02254.18 KXL44795.1 - 0.03 14.6 0.0 0.052 13.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.14 KXL44795.1 - 0.03 13.0 0.0 1.8 7.2 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein DUF3328 PF11807.8 KXL44796.1 - 0.00014 21.8 0.0 0.00014 21.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) GATase_4 PF13230.6 KXL44796.1 - 0.013 14.4 0.0 0.013 14.4 0.0 1.0 1 0 0 1 1 1 0 Glutamine amidotransferases class-II Alginate_lyase PF05426.12 KXL44798.1 - 4.1e-14 52.8 0.8 6e-14 52.2 0.8 1.2 1 0 0 1 1 1 1 Alginate lyase RPAP1_C PF08620.10 KXL44800.1 - 2.5e-27 94.8 0.0 4.9e-27 93.8 0.0 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 KXL44800.1 - 8.2e-17 60.7 1.2 1.3e-16 60.1 1.2 1.3 1 0 0 1 1 1 1 RPAP1-like, N-terminal Rtf2 PF04641.12 KXL44801.1 - 0.53 9.6 7.0 0.66 9.3 7.0 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Usp PF00582.26 KXL44801.1 - 1 9.9 5.1 4 7.9 5.1 1.8 1 1 0 1 1 1 0 Universal stress protein family DDE_1 PF03184.19 KXL44802.1 - 2.7e-05 23.9 0.0 2.9e-05 23.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease WASH_WAHD PF11945.8 KXL44803.1 - 0.0052 16.4 0.9 0.0057 16.2 0.9 1.1 1 0 0 1 1 1 1 WAHD domain of WASH complex Hexokinase_2 PF03727.16 KXL44807.1 - 1.1e-59 201.8 0.0 1.5e-59 201.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KXL44807.1 - 1.2e-43 149.3 0.0 1.8e-43 148.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase COG6 PF06419.11 KXL44808.1 - 3.9e-92 309.5 0.0 4.9e-92 309.2 0.0 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Sec34 PF04136.15 KXL44808.1 - 0.046 13.6 0.2 0.084 12.7 0.2 1.5 1 0 0 1 1 1 0 Sec34-like family AKNA PF12443.8 KXL44808.1 - 0.047 14.3 0.3 3.3 8.4 0.5 2.4 2 0 0 2 2 2 0 AT-hook-containing transcription factor Mid2 PF04478.12 KXL44809.1 - 0.0076 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor WD40 PF00400.32 KXL44810.1 - 4.3e-15 55.8 17.9 0.0016 19.2 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL44810.1 - 0.0036 17.6 0.1 0.32 11.3 0.1 3.4 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Rft-1 PF04506.13 KXL44811.1 - 1.6e-139 466.0 11.3 1.8e-139 465.8 11.3 1.0 1 0 0 1 1 1 1 Rft protein SH3_9 PF14604.6 KXL44812.1 - 7e-09 35.4 0.0 1.2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXL44812.1 - 5.4e-08 32.3 0.0 9.1e-08 31.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXL44812.1 - 6.9e-06 25.7 0.0 1.3e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF4328 PF14219.6 KXL44812.1 - 0.038 13.5 0.0 0.095 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) ANAPC3 PF12895.7 KXL44814.1 - 0.0062 16.7 1.1 0.012 15.8 0.2 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KXL44814.1 - 0.038 14.8 0.6 0.74 10.8 0.2 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat PCI PF01399.27 KXL44814.1 - 0.15 12.6 0.0 2.1 8.9 0.0 2.4 1 1 0 1 1 1 0 PCI domain Solute_trans_a PF03619.16 KXL44815.1 - 6.7e-58 196.3 19.8 8e-58 196.0 19.8 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Saf_2TM PF18303.1 KXL44815.1 - 1.3 8.5 9.0 0.73 9.4 2.1 2.7 2 1 1 3 3 3 0 SAVED-fused 2TM effector domain DNA_pol_E_B PF04042.16 KXL44816.1 - 2.1e-47 161.2 0.1 3e-47 160.7 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B SHNi-TPR PF10516.9 KXL44817.1 - 8.4e-12 44.3 0.2 2.6e-11 42.8 0.2 1.9 1 0 0 1 1 1 1 SHNi-TPR TPR_3 PF07720.12 KXL44817.1 - 0.36 10.9 3.8 0.44 10.6 2.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat SL4P PF17618.2 KXL44818.1 - 0.001 19.0 0.0 0.036 14.1 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized Strongylid L4 protein PMC2NT PF08066.12 KXL44818.1 - 0.069 13.8 0.4 0.16 12.7 0.4 1.6 1 0 0 1 1 1 0 PMC2NT (NUC016) domain YlbD_coat PF14071.6 KXL44818.1 - 0.089 13.1 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 Putative coat protein Rep_fac-A_C PF08646.10 KXL44819.1 - 8e-55 184.6 6.9 4.3e-54 182.2 3.3 2.4 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KXL44819.1 - 2.6e-36 123.4 0.2 8.1e-36 121.9 0.1 1.9 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 KXL44819.1 - 1.4e-20 73.2 0.1 3.2e-20 72.0 0.1 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 KXL44819.1 - 1e-12 47.8 0.3 1.1e-08 34.9 0.0 3.7 4 0 0 4 4 4 2 OB-fold nucleic acid binding domain DUF4539 PF15072.6 KXL44819.1 - 0.0001 22.3 0.0 0.75 9.9 0.0 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF4539) CDC24_OB3 PF17244.2 KXL44819.1 - 0.00078 19.2 0.1 0.38 10.4 0.0 3.2 3 0 0 3 3 3 1 Cell division control protein 24, OB domain 3 DUF4503 PF14951.6 KXL44819.1 - 0.12 10.8 0.1 0.2 10.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) Zn_clus PF00172.18 KXL44820.1 - 2.7e-09 37.0 7.1 2.7e-09 37.0 7.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.29 KXL44821.1 - 9.9e-51 172.0 0.3 9.8e-50 168.7 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXL44821.1 - 3e-32 111.2 0.6 1.2e-29 102.9 0.1 2.8 2 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL44821.1 - 1.8e-09 37.8 0.0 4.7e-09 36.5 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KXL44821.1 - 7.1e-05 22.1 0.2 0.00014 21.2 0.2 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SecA_DEAD PF07517.14 KXL44821.1 - 0.0081 15.5 0.0 0.018 14.3 0.0 1.7 2 0 0 2 2 2 1 SecA DEAD-like domain STAC2_u1 PF16664.5 KXL44821.1 - 0.031 14.7 2.4 3 8.3 0.0 3.0 2 1 1 3 3 3 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 CMS1 PF14617.6 KXL44821.1 - 0.054 12.8 1.3 0.13 11.6 0.0 2.1 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit UTP25 PF06862.12 KXL44821.1 - 0.1 11.3 0.1 0.22 10.3 0.1 1.5 1 1 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 KXL44821.1 - 0.11 12.8 0.1 0.41 10.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain RE_MamI PF09567.10 KXL44821.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 MamI restriction endonuclease TAF4 PF05236.14 KXL44821.1 - 0.26 11.0 9.1 0.094 12.4 6.1 1.7 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family Glyco_hydro_17 PF00332.18 KXL44823.1 - 0.0029 17.3 0.0 0.0042 16.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Kelch_3 PF13415.6 KXL44824.1 - 3.2e-05 24.1 0.0 0.00039 20.6 0.0 2.1 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.6 KXL44824.1 - 0.00042 20.2 1.9 0.0038 17.2 1.9 2.0 1 1 0 1 1 1 1 Kelch motif Kelch_1 PF01344.25 KXL44824.1 - 0.0024 17.4 0.1 0.0046 16.5 0.1 1.5 1 0 0 1 1 1 1 Kelch motif Kelch_6 PF13964.6 KXL44824.1 - 0.017 15.4 0.0 0.026 14.8 0.0 1.3 1 0 0 1 1 1 0 Kelch motif Kelch_4 PF13418.6 KXL44824.1 - 0.19 11.7 0.7 0.99 9.5 0.7 2.0 1 1 0 1 1 1 0 Galactose oxidase, central domain Kelch_4 PF13418.6 KXL44825.1 - 9e-33 112.0 12.1 1.2e-11 44.5 0.0 6.1 5 2 0 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KXL44825.1 - 1.7e-22 79.2 11.1 0.00014 22.1 0.0 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.25 KXL44825.1 - 5.8e-19 67.4 1.6 0.039 13.5 0.0 5.4 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 KXL44825.1 - 5.5e-17 61.4 4.1 0.019 15.2 0.0 5.4 4 1 1 5 5 5 5 Kelch motif Kelch_2 PF07646.15 KXL44825.1 - 1.3e-10 40.8 2.2 0.11 12.6 0.0 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 KXL44825.1 - 3.9e-09 36.3 1.1 0.0095 15.9 0.0 4.9 5 0 0 5 5 5 3 Kelch motif ASFV_J13L PF05568.11 KXL44825.1 - 0.0083 15.9 0.1 0.089 12.5 0.0 2.2 2 0 0 2 2 2 1 African swine fever virus J13L protein CBM65_1 PF18259.1 KXL44825.1 - 0.24 11.6 0.8 1.5 9.0 0.0 2.4 3 0 0 3 3 3 0 Carbohydrate binding module 65 domain 1 ADH_zinc_N_2 PF13602.6 KXL44826.1 - 2.6e-19 70.6 0.1 4e-19 70.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXL44826.1 - 6.6e-19 68.2 0.1 1.2e-18 67.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXL44826.1 - 1.2e-10 41.2 0.0 9e-08 32.0 0.0 3.1 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain TFIID-18kDa PF02269.16 KXL44827.1 - 4.8e-23 81.0 0.0 2.1e-22 78.9 0.0 2.0 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Myc_N PF01056.18 KXL44827.1 - 0.076 12.9 0.3 0.11 12.4 0.3 1.2 1 0 0 1 1 1 0 Myc amino-terminal region TP_methylase PF00590.20 KXL44828.1 - 1.8e-22 80.4 0.2 3.5e-22 79.4 0.2 1.5 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases FUSC_2 PF13515.6 KXL44829.1 - 3.4e-27 95.1 6.2 3.4e-27 95.1 6.2 2.6 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 KXL44829.1 - 3.5e-12 45.9 13.6 4.1e-06 25.9 11.5 3.2 2 1 0 2 2 2 2 Aluminium activated malate transporter ArAE_2 PF10334.9 KXL44829.1 - 0.018 14.9 0.0 0.083 12.7 0.0 2.0 2 0 0 2 2 2 0 Aromatic acid exporter family member 2 tRNA-synt_2 PF00152.20 KXL44830.1 - 6.6e-92 307.9 0.0 1e-91 307.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KXL44830.1 - 1.3e-08 34.7 0.0 2.3e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 KXL44830.1 - 0.064 13.5 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Pyr_redox_2 PF07992.14 KXL44831.1 - 1.4e-69 234.5 4.3 2.4e-69 233.8 4.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KXL44831.1 - 1e-40 138.4 0.1 2.5e-40 137.1 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KXL44831.1 - 4.7e-21 75.1 11.0 3e-19 69.3 1.2 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXL44831.1 - 1.9e-09 37.4 0.2 1.9e-09 37.4 0.2 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXL44831.1 - 6.4e-09 35.9 4.7 1.4e-05 25.3 1.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXL44831.1 - 3.7e-07 29.7 5.6 0.00011 21.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXL44831.1 - 7.1e-07 28.6 5.0 7.1e-07 28.6 5.0 2.9 2 2 1 3 3 3 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KXL44831.1 - 1.2e-06 28.0 2.5 0.019 14.3 0.1 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KXL44831.1 - 1.2e-06 27.8 3.6 1.2e-06 27.8 3.6 2.4 2 0 0 2 2 2 1 FAD binding domain K_oxygenase PF13434.6 KXL44831.1 - 7.2e-06 25.4 0.7 0.07 12.3 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KXL44831.1 - 2e-05 24.0 3.0 3e-05 23.4 0.1 2.2 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KXL44831.1 - 2.3e-05 23.3 14.5 0.00022 20.1 2.0 4.1 4 0 0 4 4 4 1 HI0933-like protein DAO PF01266.24 KXL44831.1 - 0.00021 21.0 13.0 0.0086 15.7 0.9 4.0 4 0 0 4 4 4 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXL44831.1 - 0.0097 15.0 2.9 0.025 13.6 0.2 2.3 2 1 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 KXL44831.1 - 0.024 13.9 12.0 0.6 9.3 1.6 3.6 2 1 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.6 KXL44831.1 - 0.61 10.6 3.6 7.1 7.1 0.1 2.8 2 1 0 3 3 3 0 Putative NAD(P)-binding Rad21_Rec8_N PF04825.13 KXL44832.1 - 4e-36 123.5 0.3 7e-36 122.7 0.0 1.6 2 0 0 2 2 2 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KXL44832.1 - 2.8e-07 29.7 0.0 5.9e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein E1-E2_ATPase PF00122.20 KXL44833.1 - 6.9e-45 152.8 0.1 6.9e-45 152.8 0.1 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KXL44833.1 - 2e-39 135.2 0.1 2e-39 135.2 0.1 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KXL44833.1 - 1.7e-21 77.5 4.2 1.7e-20 74.3 4.2 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXL44833.1 - 1.8e-17 62.8 0.0 3.9e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KXL44833.1 - 2.2e-13 50.1 0.0 1.2e-12 47.7 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KXL44833.1 - 2.3e-05 24.3 0.8 0.00083 19.2 0.8 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RITA PF17066.5 KXL44833.1 - 0.21 11.2 2.2 0.39 10.3 2.2 1.3 1 0 0 1 1 1 0 RBPJ-interacting and tubulin associated protein FMN_dh PF01070.18 KXL44834.1 - 1.9e-114 382.4 0.0 2.2e-114 382.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KXL44834.1 - 3e-18 65.7 0.0 7.3e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KXL44834.1 - 3.7e-05 23.0 0.0 6.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KXL44834.1 - 4e-05 22.8 0.2 0.0001 21.4 0.1 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KXL44834.1 - 0.0027 17.2 0.0 0.0049 16.3 0.0 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase FAD_binding_4 PF01565.23 KXL44835.1 - 1.5e-21 76.5 0.2 3.3e-21 75.5 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain MFS_1 PF07690.16 KXL44836.1 - 9.1e-37 126.8 26.1 9.1e-37 126.8 26.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2631 PF10939.8 KXL44836.1 - 0.58 10.0 2.8 32 4.4 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2631) Allantoicase PF03561.15 KXL44837.1 - 2.5e-92 306.4 0.0 2.2e-48 163.9 0.0 2.6 2 0 0 2 2 2 2 Allantoicase repeat DIL PF01843.19 KXL44837.1 - 9.2e-32 109.4 1.8 1e-31 109.3 0.6 1.8 2 0 0 2 2 2 1 DIL domain Ank_2 PF12796.7 KXL44837.1 - 2.8e-14 53.5 0.0 7.4e-14 52.1 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXL44837.1 - 2.2e-11 44.1 0.1 5.1e-06 26.9 0.1 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KXL44837.1 - 8.6e-10 38.6 0.1 0.0009 19.6 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KXL44837.1 - 1e-09 38.5 0.3 1.1e-08 35.2 0.0 2.9 2 1 2 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXL44837.1 - 1.4e-06 28.1 0.0 0.021 15.3 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat HATPase_c PF02518.26 KXL44838.1 - 2.5e-32 111.7 0.0 7.9e-32 110.1 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXL44838.1 - 2.6e-21 75.9 0.1 6.2e-21 74.7 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KXL44838.1 - 5.5e-20 71.2 1.0 1.7e-19 69.6 0.0 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.6 KXL44838.1 - 4.2e-17 63.0 1.9 3.2e-16 60.2 0.0 3.4 4 0 0 4 4 4 1 AAA ATPase domain GAF_2 PF13185.6 KXL44838.1 - 3e-11 43.8 0.0 1.1e-10 41.9 0.0 2.1 2 0 0 2 2 1 1 GAF domain GAF PF01590.26 KXL44838.1 - 1.3e-09 38.8 0.0 3.2e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 KXL44838.1 - 6.6e-09 35.5 0.0 1.2e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain NACHT PF05729.12 KXL44838.1 - 2.9e-05 24.0 0.1 0.14 12.1 0.0 2.9 3 0 0 3 3 2 2 NACHT domain GAF_3 PF13492.6 KXL44838.1 - 0.0007 20.0 0.0 0.0023 18.3 0.0 2.0 1 0 0 1 1 1 1 GAF domain NB-ARC PF00931.22 KXL44838.1 - 0.0035 16.6 0.0 0.0067 15.6 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain HATPase_c_3 PF13589.6 KXL44838.1 - 0.0052 16.6 0.2 0.016 15.0 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RsgA_GTPase PF03193.16 KXL44838.1 - 0.011 15.6 0.2 0.044 13.7 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase Glyco_trans_4_3 PF12000.8 KXL44838.1 - 0.028 14.1 0.0 0.11 12.2 0.0 2.0 1 0 0 1 1 1 0 Glycosyl transferase family 4 group ATPase_2 PF01637.18 KXL44838.1 - 0.041 13.8 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea SMC_N PF02463.19 KXL44838.1 - 0.044 13.2 0.0 5 6.5 0.0 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXL44838.1 - 0.061 13.6 0.0 3.9 7.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain His_Phos_1 PF00300.22 KXL44839.1 - 4.9e-12 45.9 0.1 6.6e-12 45.5 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF871 PF05913.11 KXL44839.1 - 0.0031 16.8 0.0 0.0045 16.2 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF871) ATP_bind_1 PF03029.17 KXL44840.1 - 2.5e-78 263.2 0.0 3.5e-78 262.7 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 KXL44840.1 - 3.5e-05 23.7 0.0 0.00011 22.1 0.0 1.7 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 KXL44840.1 - 4e-05 23.7 0.0 8.3e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXL44840.1 - 0.0002 21.9 0.0 0.00064 20.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KXL44840.1 - 0.00056 20.3 0.0 0.001 19.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXL44840.1 - 0.0012 19.2 0.0 0.0017 18.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXL44840.1 - 0.0024 18.1 0.0 0.0043 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXL44840.1 - 0.0031 17.7 0.0 0.005 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KXL44840.1 - 0.0036 17.0 0.0 0.0067 16.1 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 KXL44840.1 - 0.0038 17.0 0.0 0.0071 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KXL44840.1 - 0.0043 16.8 0.0 0.0062 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KXL44840.1 - 0.0044 16.1 0.0 0.0068 15.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_7 PF12775.7 KXL44840.1 - 0.0046 16.5 0.0 0.0081 15.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region cobW PF02492.19 KXL44840.1 - 0.0047 16.5 0.0 0.17 11.4 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 KXL44840.1 - 0.0074 16.7 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.12 KXL44840.1 - 0.0079 16.1 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 NACHT domain NTPase_1 PF03266.15 KXL44840.1 - 0.013 15.4 0.1 0.088 12.7 0.0 2.0 2 0 0 2 2 2 0 NTPase CbiA PF01656.23 KXL44840.1 - 0.013 15.5 0.0 0.019 15.0 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain GTP_EFTU PF00009.27 KXL44840.1 - 0.014 15.0 0.0 2.1 7.9 0.0 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain ATPase_2 PF01637.18 KXL44840.1 - 0.017 15.0 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_31 PF13614.6 KXL44840.1 - 0.021 14.8 0.0 2.5 8.0 0.0 2.3 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KXL44840.1 - 0.025 14.3 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.14 KXL44840.1 - 0.03 14.3 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 KXL44840.1 - 0.034 14.5 0.0 0.072 13.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KXL44840.1 - 0.036 14.1 0.0 0.19 11.8 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 KXL44840.1 - 0.039 14.5 0.0 0.072 13.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Thymidylate_kin PF02223.17 KXL44840.1 - 0.041 13.6 0.0 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Thymidylate kinase TsaE PF02367.17 KXL44840.1 - 0.051 13.6 0.0 0.096 12.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Septin PF00735.18 KXL44840.1 - 0.064 12.5 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Septin MobB PF03205.14 KXL44840.1 - 0.086 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATPase PF06745.13 KXL44840.1 - 0.096 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 KaiC PduV-EutP PF10662.9 KXL44840.1 - 0.11 12.3 0.0 0.54 10.0 0.0 2.0 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF463 PF04317.12 KXL44840.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 MeaB PF03308.16 KXL44840.1 - 0.14 11.1 0.0 0.29 10.1 0.0 1.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB KTI12 PF08433.10 KXL44840.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_17 PF13207.6 KXL44840.1 - 0.16 12.4 0.0 0.43 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KXL44840.1 - 0.21 10.9 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Metallophos PF00149.28 KXL44841.1 - 1.3e-11 45.4 0.0 2.2e-11 44.7 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXL44841.1 - 4.7e-08 33.4 0.1 2.3e-05 24.7 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain HTH_Tnp_Tc5 PF03221.16 KXL44843.1 - 9e-11 41.7 0.1 1.8e-10 40.7 0.1 1.5 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_28 PF13518.6 KXL44843.1 - 0.078 13.1 1.2 0.25 11.5 0.3 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_psq PF05225.16 KXL44843.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Pol_alpha_B_N PF08418.10 KXL44844.1 - 1.5e-74 251.1 0.0 2e-74 250.7 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 KXL44844.1 - 6e-34 117.3 0.0 8.7e-34 116.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B PEX11 PF05648.14 KXL44845.1 - 8.8e-08 31.9 0.2 2.8e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 Peroxisomal biogenesis factor 11 (PEX11) vWA-TerF-like PF10138.9 KXL44847.1 - 6.9e-06 26.3 0.0 1.1e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 KXL44847.1 - 0.94 9.7 2.6 4.8 7.4 1.1 2.3 2 1 0 2 2 2 0 von Willebrand factor type A domain IF3_N PF05198.16 KXL44848.1 - 2e-07 31.2 0.3 3.9e-07 30.2 0.3 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain IF3_C PF00707.22 KXL44848.1 - 3.7e-05 23.6 0.0 7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.6 KXL44848.1 - 0.0029 17.3 0.1 0.017 14.8 0.1 2.0 1 1 0 1 1 1 1 Mitochondrial translation initiation factor Apt1 PF10351.9 KXL44849.1 - 1.8e-190 633.9 3.3 1.8e-190 633.9 3.3 3.1 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27 PF10344.9 KXL44849.1 - 7.2e-174 580.3 0.0 1.4e-173 579.4 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial protein from FMP27 Fmp27_WPPW PF10359.9 KXL44849.1 - 6.6e-173 576.0 3.9 6.6e-173 576.0 3.9 1.9 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 KXL44849.1 - 2.8e-58 196.4 0.0 6.6e-58 195.2 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 KXL44849.1 - 2.4e-52 177.0 0.2 5.7e-52 175.7 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 KXL44849.1 - 1.8e-31 108.9 0.7 1.2e-30 106.3 0.0 3.0 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain JAB PF01398.21 KXL44850.1 - 7e-28 97.0 0.5 1.2e-27 96.3 0.1 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 KXL44850.1 - 1.2e-21 77.4 0.0 2.2e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 KXL44850.1 - 1e-05 25.3 0.1 4.5e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 KXL44850.1 - 0.026 14.6 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) DUF4858 PF16150.5 KXL44850.1 - 0.042 13.9 0.0 0.085 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4858) Fungal_KA1 PF16797.5 KXL44850.1 - 0.077 12.7 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Fungal kinase associated-1 domain DnaJ_C PF01556.18 KXL44851.1 - 1.5e-36 125.8 0.1 2.1e-36 125.2 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KXL44851.1 - 9e-23 80.2 1.2 1.5e-22 79.4 1.2 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KXL44851.1 - 6.1e-14 52.1 16.9 1.1e-13 51.4 16.9 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KXL44851.1 - 0.019 14.9 12.1 0.76 9.8 0.6 2.6 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KXL44851.1 - 0.23 11.5 7.5 2.2 8.3 0.9 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1356 PF07092.12 KXL44851.1 - 2.1 7.5 4.3 11 5.2 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) tRNA-synt_1c PF00749.21 KXL44852.1 - 4.8e-83 278.6 0.0 6.9e-83 278.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DUF4428 PF14471.6 KXL44852.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Meleagrin PF08189.11 KXL44854.1 - 0.075 12.7 1.0 0.15 11.8 1.0 1.4 1 0 0 1 1 1 0 Meleagrin/Cygnin family Chi-conotoxin PF16981.5 KXL44854.1 - 0.11 12.7 2.4 0.16 12.2 2.4 1.4 1 1 0 1 1 1 0 chi-Conotoxin or t superfamily PBP PF01161.20 KXL44855.1 - 4.1e-05 23.9 0.0 7.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ribosomal_L4 PF00573.22 KXL44856.1 - 9.9e-47 159.1 0.0 1.5e-46 158.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Urm1 PF09138.11 KXL44857.1 - 1.4e-35 121.5 0.0 1.6e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 KXL44857.1 - 0.0068 17.0 0.0 0.0078 16.8 0.0 1.2 1 0 0 1 1 1 1 ThiS family WD40 PF00400.32 KXL44858.1 - 4.7e-31 106.3 16.1 0.00086 20.1 0.0 11.2 11 1 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL44858.1 - 8.8e-12 45.2 2.3 0.13 12.6 0.0 6.4 4 1 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Sugar_tr PF00083.24 KXL44859.1 - 1.2e-30 106.8 9.8 1.4e-30 106.5 9.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL44859.1 - 0.0015 17.6 6.7 0.0015 17.6 6.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF998 PF06197.13 KXL44859.1 - 0.3 10.6 6.9 0.11 12.1 3.6 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF998) Yae1_N PF09811.9 KXL44861.1 - 1.7e-09 37.2 5.1 2.7e-09 36.6 5.1 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Keratin_2_head PF16208.5 KXL44861.1 - 0.1 12.7 0.2 0.15 12.2 0.2 1.2 1 0 0 1 1 1 0 Keratin type II head Romo1 PF10247.9 KXL44861.1 - 0.14 12.6 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 CBF_beta PF02312.17 KXL44862.1 - 0.022 14.4 0.3 0.022 14.4 0.3 1.8 2 0 0 2 2 2 0 Core binding factor beta subunit p450 PF00067.22 KXL44863.1 - 1e-63 215.7 0.0 1.4e-63 215.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Plasmo_rep PF12135.8 KXL44863.1 - 0.11 12.0 0.2 0.23 11.0 0.2 1.5 1 0 0 1 1 1 0 Plasmodium repeat family DUF3944 PF13099.6 KXL44863.1 - 0.13 12.1 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3944) FAD_binding_1 PF00667.20 KXL44864.1 - 9.9e-52 175.7 0.0 1.4e-51 175.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KXL44864.1 - 1.1e-25 90.5 0.0 1.9e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KXL44864.1 - 4.8e-19 69.0 0.0 1.1e-18 67.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain But2 PF09792.9 KXL44865.1 - 1.3e-56 190.9 3.8 1.3e-56 190.9 3.8 3.4 2 1 2 4 4 4 1 Ubiquitin 3 binding protein But2 C-terminal domain Arylsulfotran_2 PF14269.6 KXL44867.1 - 2.1e-39 135.7 0.6 3e-39 135.2 0.6 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXL44867.1 - 2.6e-09 36.5 3.6 1.5e-08 34.0 3.6 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) DAP3 PF10236.9 KXL44867.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Peptidase_S9 PF00326.21 KXL44868.1 - 1.6e-30 106.2 0.0 2.2e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 KXL44868.1 - 4.6e-15 55.1 6.9 5.5e-09 35.7 0.0 4.9 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat Abhydrolase_6 PF12697.7 KXL44868.1 - 6.3e-06 27.0 0.4 2.1e-05 25.3 0.4 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KXL44868.1 - 8.2e-05 22.3 0.0 0.00054 19.6 0.0 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 KXL44868.1 - 0.0001 22.3 0.0 0.0002 21.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KXL44868.1 - 0.00015 21.5 0.3 0.0008 19.1 0.3 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold DPPIV_N PF00930.21 KXL44868.1 - 0.0021 16.9 0.0 0.089 11.5 0.0 3.0 1 1 1 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Abhydrolase_2 PF02230.16 KXL44868.1 - 0.0035 17.2 0.1 3.4 7.4 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase AXE1 PF05448.12 KXL44868.1 - 0.014 14.1 0.0 0.023 13.4 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 KXL44868.1 - 0.017 14.4 0.1 0.9 8.7 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 ANAPC4_WD40 PF12894.7 KXL44868.1 - 0.027 14.8 0.0 17 5.8 0.0 4.3 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain Abhydrolase_4 PF08386.10 KXL44868.1 - 0.084 13.0 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein FlaE PF07559.14 KXL44868.1 - 0.11 13.1 0.0 0.22 12.1 0.0 1.5 1 0 0 1 1 1 0 Flagellar basal body protein FlaE Methyltransf_25 PF13649.6 KXL44869.1 - 9e-08 32.7 0.0 2e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXL44869.1 - 1.3e-07 31.6 0.0 1.9e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL44869.1 - 6.3e-07 29.3 0.0 1.2e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL44869.1 - 4.4e-06 27.4 0.0 1.3e-05 25.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL44869.1 - 0.00015 22.4 0.0 0.00031 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXL44869.1 - 0.0056 16.2 0.0 0.019 14.4 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase DUF2451 PF10474.9 KXL44869.1 - 0.19 11.5 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) QLQ PF08880.11 KXL44869.1 - 0.98 9.2 3.2 17 5.3 0.1 2.7 3 0 0 3 3 3 0 QLQ 120_Rick_ant PF12574.8 KXL44870.1 - 0.043 13.0 0.0 0.071 12.3 0.0 1.2 1 0 0 1 1 1 0 120 KDa Rickettsia surface antigen Radial_spoke_3 PF06098.11 KXL44870.1 - 0.067 12.5 0.0 0.097 11.9 0.0 1.2 1 0 0 1 1 1 0 Radial spoke protein 3 Mito_carr PF00153.27 KXL44871.1 - 2.4e-72 238.9 0.1 2.6e-24 84.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXL44871.1 - 0.0017 17.6 0.1 1.5 7.9 0.0 3.1 3 0 0 3 3 3 2 Gammaproteobacterial serine protease CIA30 PF08547.12 KXL44872.1 - 1.8e-40 138.6 0.0 2.3e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) SGBP_B_XBD PF18329.1 KXL44872.1 - 0.0027 17.7 0.0 0.0035 17.3 0.0 1.2 1 0 0 1 1 1 1 Surface glycan-binding protein B xyloglucan binding domain DUF3128 PF11326.8 KXL44873.1 - 0.039 14.3 0.0 0.082 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) Acatn PF13000.7 KXL44874.1 - 6.9e-164 546.4 16.0 3.9e-83 279.8 5.0 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 MFS_1_like PF12832.7 KXL44874.1 - 0.00038 19.4 6.0 0.00038 19.4 6.0 1.8 2 0 0 2 2 2 1 MFS_1 like family EI24 PF07264.11 KXL44875.1 - 1.6e-11 44.8 1.7 0.00015 22.1 2.9 2.1 1 1 1 2 2 2 2 Etoposide-induced protein 2.4 (EI24) FmdA_AmdA PF03069.15 KXL44876.1 - 5.6e-177 588.2 0.0 6.4e-177 588.0 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family p450 PF00067.22 KXL44877.1 - 5.3e-52 177.1 0.0 9.7e-52 176.2 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 MIT PF04212.18 KXL44879.1 - 1.1e-15 57.4 1.5 2.5e-15 56.3 1.5 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain zf-UBR PF02207.20 KXL44880.1 - 1.4e-17 63.6 16.3 1.4e-17 63.6 16.3 2.1 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KXL44880.1 - 3.3e-07 30.0 0.5 2.2e-06 27.3 0.2 2.4 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS UCR_UQCRX_QCR9 PF05365.12 KXL44881.1 - 4.7e-18 64.9 0.9 5e-18 64.8 0.9 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Mago-bind PF09282.10 KXL44882.1 - 4e-15 55.4 2.4 7.4e-15 54.5 2.4 1.5 1 0 0 1 1 1 1 Mago binding GTSE1_N PF15259.6 KXL44882.1 - 0.0017 18.6 1.0 0.0024 18.1 1.0 1.4 1 0 0 1 1 1 1 G-2 and S-phase expressed 1 DUF4407 PF14362.6 KXL44882.1 - 0.22 10.9 5.0 0.25 10.7 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LegC3_N PF18654.1 KXL44883.1 - 0.016 14.5 0.3 0.016 14.5 0.3 2.2 2 0 0 2 2 2 0 LegC3 N-terminal coiled-coil domain Scm3 PF10384.9 KXL44883.1 - 0.055 13.2 0.1 0.64 9.8 0.0 2.7 3 0 0 3 3 3 0 Centromere protein Scm3 Perilipin PF03036.16 KXL44884.1 - 0.099 11.7 0.0 0.099 11.7 0.0 1.1 1 0 0 1 1 1 0 Perilipin family Band_7 PF01145.25 KXL44886.1 - 3.8e-18 66.1 0.6 3.8e-18 66.1 0.6 3.0 3 1 0 3 3 3 1 SPFH domain / Band 7 family PhzC-PhzF PF02567.16 KXL44887.1 - 4.2e-44 151.1 0.0 5e-44 150.9 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein DUF3328 PF11807.8 KXL44888.1 - 9.4e-40 136.7 0.2 1.3e-39 136.3 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) zf-CCCH_2 PF14608.6 KXL44889.1 - 2.1e-10 40.7 49.3 5.5e-05 23.5 6.0 5.4 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger Nab2p_Zf1 PF18260.1 KXL44889.1 - 0.031 14.2 1.7 0.062 13.2 0.1 2.3 2 0 0 2 2 2 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 ANAPC4_WD40 PF12894.7 KXL44890.1 - 3.6e-06 27.2 0.0 0.47 10.8 0.1 4.4 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXL44890.1 - 1.8e-05 25.4 0.2 38 5.4 0.0 5.6 5 1 0 5 5 5 2 WD domain, G-beta repeat PD40 PF07676.12 KXL44890.1 - 0.12 12.3 0.0 2.7 8.0 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat 6PGD PF00393.19 KXL44891.1 - 1.3e-128 428.5 0.0 1.6e-128 428.1 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KXL44891.1 - 2.9e-50 170.5 0.0 4.4e-50 169.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sas6_CC PF18594.1 KXL44891.1 - 0.047 13.5 0.5 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain RRM_1 PF00076.22 KXL44892.1 - 2.5e-14 52.8 0.0 4.1e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) XS PF03468.14 KXL44892.1 - 0.093 13.0 0.1 0.19 12.1 0.1 1.5 1 1 0 1 1 1 0 XS domain AD PF09793.9 KXL44893.1 - 3.7e-30 103.9 2.5 6.3e-30 103.2 2.5 1.4 1 0 0 1 1 1 1 Anticodon-binding domain Sugar_tr PF00083.24 KXL44894.1 - 1e-80 271.9 24.7 1.1e-80 271.7 24.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL44894.1 - 2.1e-26 92.7 24.0 6.4e-26 91.1 20.9 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Phage_Nu1 PF07471.12 KXL44894.1 - 0.11 12.2 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 Tom6 PF17112.5 KXL44894.1 - 0.13 11.8 1.6 0.67 9.5 0.2 2.6 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom6, fungal Kinesin PF00225.23 KXL44896.1 - 1.1e-83 280.9 0.1 1.6e-83 280.4 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXL44896.1 - 9.5e-22 77.5 0.0 2.1e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding HHH_5 PF14520.6 KXL44896.1 - 0.011 16.4 0.1 0.65 10.6 0.1 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix domain HHH PF00633.23 KXL44896.1 - 0.045 13.6 0.7 0.43 10.5 0.1 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif HHH_3 PF12836.7 KXL44896.1 - 0.059 13.6 0.0 0.2 11.9 0.0 1.9 1 1 0 1 1 1 0 Helix-hairpin-helix motif TPR_14 PF13428.6 KXL44896.1 - 0.11 13.3 0.1 0.38 11.7 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat PBP1_TM PF14812.6 KXL44896.1 - 0.45 10.9 2.6 1.2 9.5 2.6 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ARGLU PF15346.6 KXL44896.1 - 3.5 7.5 8.4 3.3 7.6 6.8 1.8 1 1 0 1 1 1 0 Arginine and glutamate-rich 1 Gly_transf_sug PF04488.15 KXL44898.1 - 7.9e-15 55.3 0.3 1.7e-14 54.2 0.2 1.5 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KXL44898.1 - 0.0064 15.9 0.0 0.0075 15.7 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 KXL44898.1 - 0.16 11.2 0.3 0.52 9.5 0.1 1.8 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Cyt-b5 PF00173.28 KXL44900.1 - 7.7e-18 64.4 0.2 8.6e-18 64.3 0.2 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BRX PF08381.11 KXL44900.1 - 0.18 11.2 1.4 3.7 7.0 1.4 2.7 1 1 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 MFS_1 PF07690.16 KXL44901.1 - 4.8e-35 121.1 26.5 4.8e-35 121.1 26.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily LapA_dom PF06305.11 KXL44901.1 - 0.88 9.4 4.7 5.1 7.0 0.1 4.1 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF1993 PF09351.10 KXL44902.1 - 2.6e-58 196.7 0.0 2.9e-58 196.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) DUF3867 PF12983.7 KXL44902.1 - 0.011 15.7 0.1 0.015 15.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3867) DnaJ_C PF01556.18 KXL44903.1 - 1.4e-26 93.3 0.0 2.3e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KXL44903.1 - 6e-25 87.2 5.6 1e-24 86.4 5.6 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KXL44903.1 - 1.2e-13 51.2 20.5 1.9e-13 50.6 20.5 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KXL44903.1 - 1.4e-05 25.0 7.3 0.0098 15.8 1.8 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KXL44903.1 - 0.0069 16.4 9.0 0.31 11.1 1.4 2.4 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 KXL44903.1 - 0.55 9.9 7.7 1.8 8.2 0.3 2.3 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Acetyltransf_10 PF13673.7 KXL44904.1 - 2e-08 34.2 0.0 2.8e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXL44904.1 - 3.7e-08 33.7 0.2 5.5e-08 33.1 0.2 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXL44904.1 - 5.1e-06 26.7 0.5 1.5e-05 25.2 0.5 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KXL44904.1 - 0.013 15.6 0.2 0.027 14.5 0.1 1.8 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain MutS_V PF00488.21 KXL44905.1 - 1.8e-81 272.7 0.1 3.8e-81 271.6 0.1 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXL44905.1 - 2.3e-36 125.8 1.3 4.6e-36 124.8 0.2 2.1 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 KXL44905.1 - 1.1e-21 77.6 0.1 3.9e-21 75.8 0.1 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KXL44905.1 - 4.9e-17 62.1 2.6 1.4e-16 60.6 1.1 2.6 2 0 0 2 2 2 1 MutS family domain IV MutS_I PF01624.20 KXL44905.1 - 9.6e-16 58.0 0.0 1.1e-14 54.6 0.0 2.4 2 0 0 2 2 2 1 MutS domain I Rpn9_C PF18261.1 KXL44905.1 - 0.31 10.7 5.8 3 7.5 0.3 2.7 2 0 0 2 2 2 0 Rpn9 C-terminal helix PDZ_1 PF12812.7 KXL44906.1 - 1.6e-51 172.2 0.0 7.9e-34 115.5 0.0 2.7 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 KXL44906.1 - 9.1e-28 98.0 1.3 8.8e-22 78.6 0.1 2.9 3 0 0 3 3 3 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 KXL44906.1 - 1.3e-13 50.6 0.3 1.6e-07 31.1 0.2 4.2 4 0 0 4 4 4 2 PDZ domain PDZ_2 PF13180.6 KXL44906.1 - 9.8e-13 48.2 0.1 5.9e-06 26.5 0.1 4.6 4 0 0 4 4 4 2 PDZ domain PDZ PF00595.24 KXL44906.1 - 1.6e-12 47.6 0.0 1.6e-06 28.4 0.0 3.6 3 0 0 3 3 3 2 PDZ domain Tricorn_PDZ PF14685.6 KXL44906.1 - 0.00074 19.4 1.7 0.28 11.2 0.2 3.1 2 0 0 2 2 2 2 Tricorn protease PDZ domain Trypsin PF00089.26 KXL44906.1 - 0.0015 18.4 0.0 0.0068 16.2 0.0 2.0 1 1 0 1 1 1 1 Trypsin 4HPAD_g_N PF18671.1 KXL44906.1 - 0.0034 17.1 0.0 0.015 15.0 0.0 2.1 1 0 0 1 1 1 1 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Peptidase_S46 PF10459.9 KXL44906.1 - 0.071 11.7 0.1 0.13 10.9 0.1 1.3 1 0 0 1 1 1 0 Peptidase S46 DUF31 PF01732.16 KXL44906.1 - 0.14 11.7 0.2 0.21 11.1 0.2 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S7 PF00949.21 KXL44906.1 - 0.19 11.5 0.1 0.49 10.2 0.1 1.6 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Glypican PF01153.19 KXL44907.1 - 0.14 11.0 3.2 0.16 10.8 3.2 1.1 1 0 0 1 1 1 0 Glypican Red1 PF07964.11 KXL44907.1 - 0.21 9.8 2.6 0.35 9.1 1.7 1.7 2 0 0 2 2 2 0 Rec10 / Red1 DUF4674 PF15719.5 KXL44907.1 - 2.1 8.4 7.8 2.8 7.9 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) 3HCDH_N PF02737.18 KXL44909.1 - 3.8e-37 127.9 0.0 5.9e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KXL44909.1 - 1.6e-12 47.9 0.0 2.9e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_8 PF13450.6 KXL44909.1 - 0.00019 21.6 0.0 0.00053 20.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXL44909.1 - 0.0041 16.8 0.0 0.0076 15.9 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KXL44909.1 - 0.012 14.9 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KXL44909.1 - 0.017 14.3 0.0 0.041 13.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ldh_1_N PF00056.23 KXL44909.1 - 0.03 14.4 0.0 0.058 13.5 0.0 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ApbA PF02558.16 KXL44909.1 - 0.034 13.8 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 KXL44909.1 - 0.064 13.8 0.0 0.12 13.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 KXL44909.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.6 KXL44909.1 - 0.16 12.0 0.1 0.35 10.8 0.0 1.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 KXL44909.1 - 0.17 11.1 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family AMP-binding PF00501.28 KXL44910.1 - 6.3e-84 282.0 0.1 7.9e-84 281.7 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXL44910.1 - 1e-16 61.6 0.3 2.5e-16 60.4 0.3 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Rho_RNA_bind PF07497.12 KXL44910.1 - 0.066 13.1 0.0 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Rho termination factor, RNA-binding domain Inp1 PF12634.7 KXL44911.1 - 1.2e-24 86.9 0.1 1.5e-23 83.3 0.0 2.7 2 1 0 2 2 2 1 Inheritance of peroxisomes protein 1 Glyco_transf_25 PF01755.17 KXL44912.1 - 1.6e-12 47.7 0.0 1.6e-09 37.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Foie-gras_1 PF11817.8 KXL44912.1 - 0.045 13.3 0.1 0.071 12.7 0.1 1.2 1 0 0 1 1 1 0 Foie gras liver health family 1 INTS5_C PF14838.6 KXL44913.1 - 0.042 12.5 0.0 0.042 12.5 0.0 1.0 1 0 0 1 1 1 0 Integrator complex subunit 5 C-terminus Catalase PF00199.19 KXL44913.1 - 0.083 12.0 0.0 0.098 11.7 0.0 1.1 1 0 0 1 1 1 0 Catalase HATPase_c PF02518.26 KXL44915.1 - 1.4e-27 96.4 0.4 2.8e-27 95.5 0.4 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KXL44915.1 - 3e-19 68.8 0.2 1.1e-18 67.0 0.1 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 KXL44915.1 - 6.3e-19 68.1 1.1 4.1e-11 43.0 0.3 3.6 3 0 0 3 3 3 3 PAS fold Response_reg PF00072.24 KXL44915.1 - 2.1e-18 66.5 0.0 8.2e-18 64.6 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain PAS PF00989.25 KXL44915.1 - 9.7e-15 54.6 0.0 1.5e-08 34.7 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 KXL44915.1 - 1.2e-09 38.4 0.6 1.5e-07 31.7 0.1 3.1 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.7 KXL44915.1 - 6.5e-08 32.8 0.0 1.3e-05 25.4 0.0 3.5 3 0 0 3 3 3 1 PAS domain PAS_8 PF13188.7 KXL44915.1 - 0.00045 20.2 0.0 0.086 12.9 0.0 2.7 2 0 0 2 2 2 1 PAS domain PAS_10 PF13596.6 KXL44915.1 - 0.0034 18.0 0.0 0.0093 16.5 0.0 1.8 1 0 0 1 1 1 1 PAS domain Aldedh PF00171.22 KXL44916.1 - 5.9e-10 38.2 5.3 3.4e-09 35.7 3.2 2.5 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Glyco_hydro_16 PF00722.21 KXL44917.1 - 7.2e-43 146.1 5.2 1.1e-42 145.5 5.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1080 PF06439.11 KXL44917.1 - 0.014 15.5 0.5 0.022 14.9 0.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1080) Glyco_hydro_20 PF00728.22 KXL44918.1 - 4.4e-84 282.9 0.1 5.5e-84 282.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KXL44918.1 - 5.4e-28 98.3 0.1 1.5e-27 96.9 0.0 1.7 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KXL44918.1 - 4.9e-07 30.6 0.0 8.7e-06 26.5 0.0 2.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Ribosomal_L7Ae PF01248.26 KXL44919.1 - 4e-23 81.0 0.0 4.5e-23 80.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L16 PF00252.18 KXL44920.1 - 1.9e-45 154.1 0.1 2.4e-45 153.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e MBOAT PF03062.19 KXL44921.1 - 1e-41 143.5 9.7 1e-41 143.5 9.7 2.2 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KXL44921.1 - 1.1e-06 28.8 4.6 2.6e-06 27.6 4.6 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Ank_4 PF13637.6 KXL44922.1 - 0.0035 17.9 0.1 2.1 9.1 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXL44922.1 - 0.0047 17.5 0.1 0.13 12.8 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) SnoaL_2 PF12680.7 KXL44923.1 - 0.0027 18.3 0.1 0.0075 16.9 0.0 1.8 2 0 0 2 2 2 1 SnoaL-like domain DLH PF01738.18 KXL44923.1 - 0.033 13.8 0.0 0.45 10.0 0.0 2.2 1 1 1 2 2 2 0 Dienelactone hydrolase family SnoaL PF07366.12 KXL44923.1 - 0.046 13.5 0.0 0.091 12.6 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase SIR2 PF02146.17 KXL44924.1 - 2e-56 190.7 0.0 3e-56 190.1 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KXL44924.1 - 0.11 12.3 0.0 3.7 7.3 0.0 2.6 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, central domain COG4 PF08318.12 KXL44925.1 - 8.9e-118 393.2 0.0 1.2e-117 392.8 0.0 1.1 1 0 0 1 1 1 1 COG4 transport protein DHR10 PF18595.1 KXL44925.1 - 0.23 11.5 1.3 2.1 8.4 0.3 2.4 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Mg_trans_NIPA PF05653.14 KXL44926.1 - 2.2e-91 306.0 24.6 2.8e-91 305.7 24.6 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KXL44926.1 - 2.3e-06 27.8 5.7 2.3e-06 27.8 5.7 3.2 3 0 0 3 3 3 2 EamA-like transporter family DUF805 PF05656.14 KXL44926.1 - 1 9.8 10.2 1.4 9.4 2.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Mo25 PF08569.11 KXL44927.1 - 7.6e-123 410.0 0.0 8.6e-123 409.9 0.0 1.0 1 0 0 1 1 1 1 Mo25-like DUF325 PF03804.13 KXL44928.1 - 0.088 12.9 0.7 0.088 12.9 0.7 3.4 2 1 1 3 3 3 0 Viral proteins of unknown function TRI12 PF06609.13 KXL44930.1 - 6.3e-67 226.3 17.9 8.3e-67 226.0 17.9 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KXL44930.1 - 2e-20 73.0 58.1 1.9e-18 66.5 55.0 3.2 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL44930.1 - 8.7e-09 34.7 6.8 8.7e-09 34.7 6.8 3.0 3 1 0 3 3 3 1 Sugar (and other) transporter PEN-2 PF10251.9 KXL44930.1 - 1 9.8 4.7 2.9 8.4 1.5 2.7 2 0 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase MFS_1 PF07690.16 KXL44931.1 - 3.2e-18 65.8 38.1 2.1e-17 63.1 8.4 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily NADH-u_ox-rdase PF10785.9 KXL44931.1 - 0.79 10.5 5.4 1e+02 3.7 0.1 4.1 3 1 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Arylsulfotran_2 PF14269.6 KXL44932.1 - 4.8e-46 157.5 1.8 6.2e-46 157.1 1.8 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXL44932.1 - 4.8e-16 58.6 2.7 1.3e-14 53.9 2.7 2.2 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) DUF5601 PF18151.1 KXL44932.1 - 0.22 11.9 0.4 0.62 10.4 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) Sulfotransfer_4 PF17784.1 KXL44933.1 - 1.2e-72 244.2 0.3 1.5e-72 243.9 0.3 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXL44933.1 - 1.3e-05 25.7 0.0 0.0019 18.6 0.0 2.3 1 1 1 2 2 2 2 Sulfotransferase family DUF1572 PF07609.11 KXL44933.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1572) HECT PF00632.25 KXL44934.1 - 1.9e-74 251.0 0.0 2.7e-74 250.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Fungal_trans_2 PF11951.8 KXL44935.1 - 2.7e-09 36.3 0.6 3.8e-09 35.8 0.2 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL44935.1 - 4.7e-09 36.2 9.9 4.7e-09 36.2 9.9 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MCM_OB PF17207.3 KXL44935.1 - 0.11 12.4 4.3 0.18 11.7 3.5 1.7 2 0 0 2 2 2 0 MCM OB domain Ribosomal_L15e PF00827.17 KXL44936.1 - 2.2e-91 304.8 10.5 2.7e-91 304.5 10.5 1.0 1 0 0 1 1 1 1 Ribosomal L15 AhpC-TSA PF00578.21 KXL44937.1 - 4.2e-32 110.7 0.0 6e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXL44937.1 - 8.7e-16 58.0 0.0 1.1e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KXL44937.1 - 1.7e-14 53.4 0.1 4e-14 52.2 0.1 1.7 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin NfrA_C PF13283.6 KXL44938.1 - 0.093 12.2 0.0 0.2 11.1 0.0 1.5 1 1 0 1 1 1 0 Bacteriophage N adsorption protein A C-term Abhydrolase_1 PF00561.20 KXL44939.1 - 2.2e-20 73.4 0.2 2e-16 60.4 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXL44939.1 - 6.9e-14 51.7 0.5 9.4e-14 51.3 0.5 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXL44939.1 - 8.5e-11 42.9 0.1 1.1e-10 42.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KXL44939.1 - 0.00016 21.4 0.0 0.00035 20.3 0.0 1.5 1 1 0 1 1 1 1 Putative esterase Ndr PF03096.14 KXL44939.1 - 0.0023 16.7 0.0 0.0035 16.1 0.0 1.2 1 0 0 1 1 1 1 Ndr family Ser_hydrolase PF06821.13 KXL44939.1 - 0.0095 15.8 0.0 0.96 9.3 0.0 2.3 2 0 0 2 2 2 1 Serine hydrolase BAAT_C PF08840.11 KXL44939.1 - 0.013 15.4 3.0 0.026 14.5 0.2 2.6 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 KXL44939.1 - 0.02 14.5 0.5 0.27 10.9 0.3 2.4 1 1 1 2 2 2 0 Serine hydrolase (FSH1) Peptidase_S10 PF00450.22 KXL44939.1 - 0.032 13.6 0.0 0.083 12.3 0.0 1.5 1 1 1 2 2 2 0 Serine carboxypeptidase PGAP1 PF07819.13 KXL44939.1 - 0.053 13.2 0.1 0.087 12.5 0.1 1.5 1 1 0 1 1 1 0 PGAP1-like protein Arylsulfotran_2 PF14269.6 KXL44941.1 - 9.2e-44 150.0 0.2 8.3e-39 133.7 0.1 2.2 2 0 0 2 2 2 2 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXL44941.1 - 7.3e-11 41.6 0.3 2e-10 40.2 0.3 1.8 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Aminotran_1_2 PF00155.21 KXL44944.1 - 2.6e-58 197.9 0.0 3.1e-58 197.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 KXL44944.1 - 0.014 14.3 0.0 0.02 13.8 0.0 1.1 1 0 0 1 1 1 0 Allinase Cys_Met_Meta_PP PF01053.20 KXL44944.1 - 0.17 10.4 0.0 0.27 9.7 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme T2SSM PF04612.12 KXL44945.1 - 0.18 11.9 0.0 0.8 9.7 0.0 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M DUF3984 PF13136.6 KXL44945.1 - 1.7 7.9 11.5 3.3 7.0 8.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3984) UQ_con PF00179.26 KXL44946.1 - 4e-51 172.3 0.0 4.6e-51 172.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXL44946.1 - 0.0014 18.3 0.0 0.0016 18.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KXL44946.1 - 0.089 13.1 0.0 0.15 12.4 0.0 1.4 1 1 0 1 1 1 0 RWD domain zf-C2H2_2 PF12756.7 KXL44947.1 - 0.0076 16.6 0.4 0.013 15.8 0.4 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-DNA_Pol PF08996.10 KXL44947.1 - 0.042 13.6 0.2 3.2 7.5 0.5 2.2 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger DUF3712 PF12505.8 KXL44947.1 - 0.1 12.9 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3712) OPT PF03169.15 KXL44948.1 - 2.4e-149 498.8 15.8 2.8e-149 498.6 15.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2207 PF09972.9 KXL44948.1 - 0.069 11.9 1.4 7.7 5.2 0.1 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) GNVR PF13807.6 KXL44948.1 - 1.2 9.1 2.6 11 6.0 0.0 3.3 3 0 0 3 3 3 0 G-rich domain on putative tyrosine kinase zf-C3HC4 PF00097.25 KXL44952.1 - 0.0081 16.0 8.6 0.021 14.7 7.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXL44952.1 - 0.024 14.6 8.2 0.066 13.2 8.2 1.9 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXL44952.1 - 0.032 14.2 6.5 0.041 13.9 5.2 2.0 2 0 0 2 2 2 0 RING-type zinc-finger Lipase_GDSL_2 PF13472.6 KXL44955.1 - 4.3e-18 66.3 0.0 5.3e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXL44955.1 - 0.00047 20.2 0.0 0.0019 18.2 0.0 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Uso1_p115_head PF04869.14 KXL44956.1 - 3.5e-41 141.4 0.0 4.1e-40 137.8 0.0 2.5 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 KXL44956.1 - 3.4e-09 37.1 23.7 3.4e-09 37.1 23.7 4.5 1 1 3 4 4 4 1 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2353 PF09789.9 KXL44956.1 - 4.3e-05 23.0 16.6 4.3e-05 23.0 16.6 2.4 1 1 1 2 2 2 1 Uncharacterized coiled-coil protein (DUF2353) BRE1 PF08647.11 KXL44956.1 - 0.00073 19.6 7.0 0.00073 19.6 7.0 4.0 3 1 1 4 4 4 1 BRE1 E3 ubiquitin ligase APG6_N PF17675.1 KXL44956.1 - 0.0058 17.2 19.3 0.0058 17.2 19.3 4.8 2 1 3 5 5 5 1 Apg6 coiled-coil region AAA_13 PF13166.6 KXL44956.1 - 0.4 9.3 41.6 0.031 12.9 23.0 2.1 1 1 1 2 2 2 0 AAA domain DUF812 PF05667.11 KXL44956.1 - 1.7 7.4 49.8 2.4 7.0 49.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) CENP-F_leu_zip PF10473.9 KXL44956.1 - 1.9 8.5 64.5 0.036 14.1 18.5 4.2 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pox_A_type_inc PF04508.12 KXL44956.1 - 5.1 7.1 6.2 11 6.0 0.2 3.9 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Laminin_II PF06009.12 KXL44956.1 - 6.6 6.8 34.3 14 5.7 5.3 3.5 1 1 2 3 3 3 0 Laminin Domain II MFS_1 PF07690.16 KXL44957.1 - 3.3e-37 128.3 54.8 1.4e-36 126.1 53.8 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily PTR2 PF00854.21 KXL44957.1 - 1.2 7.9 12.9 0.033 13.0 0.6 2.2 2 0 0 2 2 2 0 POT family Piwi PF02171.17 KXL44960.1 - 7.4e-69 232.3 0.0 1.3e-68 231.5 0.0 1.4 1 1 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KXL44960.1 - 1.3e-18 67.9 0.1 4.7e-18 66.1 0.1 2.0 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KXL44960.1 - 1.2e-14 53.7 0.3 3.2e-14 52.3 0.3 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 KXL44960.1 - 6e-11 42.3 0.0 1.5e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 KXL44960.1 - 1e-09 38.6 0.1 3.5e-09 36.9 0.1 2.0 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 KXL44960.1 - 0.00058 20.1 0.0 0.0015 18.7 0.0 1.7 1 0 0 1 1 1 1 Mid domain of argonaute HTH_OrfB_IS605 PF12323.8 KXL44960.1 - 0.51 9.9 1.6 0.55 9.8 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain p450 PF00067.22 KXL44961.1 - 2.4e-62 211.2 0.0 3.4e-62 210.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 LapA_dom PF06305.11 KXL44962.1 - 4.6 7.1 5.6 1.9 8.4 1.1 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Methyltransf_23 PF13489.6 KXL44963.1 - 6.2e-09 35.9 0.0 8.2e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL44963.1 - 7.5e-05 23.4 0.0 0.00016 22.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL44963.1 - 9.5e-05 23.0 0.0 0.00015 22.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL44963.1 - 0.00017 22.3 0.0 0.00028 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Spc7 PF08317.11 KXL44964.1 - 0.0084 15.0 2.9 0.011 14.6 2.9 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein ARGLU PF15346.6 KXL44964.1 - 0.018 14.9 9.5 0.028 14.3 9.5 1.2 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 EzrA PF06160.12 KXL44964.1 - 0.037 12.2 2.3 0.05 11.8 2.3 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA SCAPER_N PF16501.5 KXL44964.1 - 0.037 14.0 0.1 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 S phase cyclin A-associated protein in the endoplasmic reticulum LRS4 PF10422.9 KXL44964.1 - 0.043 13.4 7.0 0.063 12.9 7.0 1.3 1 1 0 1 1 1 0 Monopolin complex subunit LRS4 DUF4407 PF14362.6 KXL44964.1 - 0.057 12.8 1.5 0.062 12.7 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ApoLp-III PF07464.11 KXL44964.1 - 0.062 13.4 1.5 0.11 12.6 1.5 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF3808 PF10300.9 KXL44964.1 - 0.086 11.6 1.3 0.11 11.2 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) KxDL PF10241.9 KXL44964.1 - 0.087 13.1 6.4 0.17 12.2 6.4 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein ABC_tran_CTD PF16326.5 KXL44964.1 - 0.15 12.3 2.8 0.29 11.4 2.8 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain FlaC_arch PF05377.11 KXL44964.1 - 0.19 12.1 0.7 0.42 11.0 0.7 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) ATG16 PF08614.11 KXL44964.1 - 0.2 11.9 12.3 0.11 12.7 9.4 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Med2 PF11214.8 KXL44964.1 - 0.46 10.7 4.1 0.15 12.2 1.2 1.8 2 0 0 2 2 2 0 Mediator complex subunit 2 Exonuc_VII_L PF02601.15 KXL44964.1 - 1.7 8.2 9.5 2.3 7.7 9.5 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit XhlA PF10779.9 KXL44964.1 - 3.7 7.8 5.8 2.1 8.6 2.1 2.2 1 1 1 2 2 2 0 Haemolysin XhlA Methyltransf_31 PF13847.6 KXL44965.1 - 2.3e-14 53.5 0.1 3.1e-14 53.0 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL44965.1 - 1e-12 48.6 0.0 1.8e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL44965.1 - 3.9e-08 33.8 0.0 6.9e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXL44965.1 - 1.8e-07 30.7 0.0 2.8e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KXL44965.1 - 0.002 18.0 0.0 0.0025 17.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXL44965.1 - 0.0034 17.2 0.1 0.0074 16.1 0.1 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KXL44965.1 - 0.018 14.5 0.2 0.028 13.8 0.2 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DOT1 PF08123.13 KXL44965.1 - 0.22 11.0 0.9 2.1 7.8 0.1 2.2 1 1 0 2 2 2 0 Histone methylation protein DOT1 Npa1 PF11707.8 KXL44967.1 - 2.5e-85 286.9 0.2 6.5e-85 285.5 0.0 1.8 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 KXL44967.1 - 4.3e-58 196.2 0.0 1.1e-57 194.9 0.0 1.8 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 GST_N_2 PF13409.6 KXL44969.1 - 2.6e-22 78.9 0.1 7.9e-22 77.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXL44969.1 - 1.7e-15 56.8 0.0 4.5e-15 55.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXL44969.1 - 4.7e-07 29.9 0.0 1e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXL44969.1 - 3.1e-05 24.3 0.0 0.00079 19.8 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXL44969.1 - 0.00027 21.1 0.1 0.00055 20.1 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KXL44969.1 - 0.031 14.8 0.0 0.057 14.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DEP PF00610.21 KXL44970.1 - 2.1e-22 78.9 0.2 5.6e-22 77.6 0.2 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) IML1 PF12257.8 KXL44971.1 - 1.2e-85 287.2 0.0 1.1e-84 284.0 0.0 1.9 1 1 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DUF4743 PF15916.5 KXL44972.1 - 7.8e-14 51.7 0.0 1.2e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 KXL44972.1 - 2e-10 40.8 0.0 3.6e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain RNA_pol_Rpb8 PF03870.15 KXL44973.1 - 2.6e-41 141.1 0.0 2.8e-41 140.9 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 KXL44973.1 - 0.03 14.4 0.0 3.3 7.8 0.0 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase, subunit G DUF775 PF05603.12 KXL44974.1 - 4.9e-66 222.1 0.0 5.5e-66 221.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) NAD_binding_10 PF13460.6 KXL44977.1 - 0.001 19.0 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Metallophos PF00149.28 KXL44978.1 - 1.5e-35 123.6 0.0 2.5e-35 122.8 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NAAA-beta PF15508.6 KXL44978.1 - 9.9e-14 51.4 0.0 2.3e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase HeLo PF14479.6 KXL44980.1 - 1.8e-39 135.8 0.0 4.7e-39 134.4 0.0 1.6 2 0 0 2 2 2 1 Prion-inhibition and propagation Pro-kuma_activ PF09286.11 KXL44981.1 - 3.5e-43 147.3 0.0 5.2e-42 143.5 0.0 2.2 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain DUF5609 PF18429.1 KXL44981.1 - 0.18 11.6 0.1 0.96 9.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5609) SMN PF06003.12 KXL44982.1 - 0.00029 20.2 11.7 0.018 14.3 2.1 2.3 1 1 0 2 2 2 2 Survival motor neuron protein (SMN) RRM_1 PF00076.22 KXL44983.1 - 1.4e-10 40.8 0.0 2.6e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXL44983.1 - 0.058 13.4 0.1 0.16 12.0 0.0 1.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Acyl_transf_1 PF00698.21 KXL44984.1 - 1.4e-21 77.4 0.0 1e-16 61.4 0.1 2.1 2 0 0 2 2 2 2 Acyl transferase domain GST_N PF02798.20 KXL44985.1 - 1.1e-10 41.7 0.0 1.6e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXL44985.1 - 2.9e-09 37.2 0.0 4.8e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXL44985.1 - 6.3e-09 36.0 0.0 1.1e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXL44985.1 - 2.8e-05 24.2 0.0 5.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXL44985.1 - 4.9e-05 23.3 0.1 9.3e-05 22.4 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXL44985.1 - 9.2e-05 22.6 0.0 0.00016 21.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Vut_1 PF02592.15 KXL44985.1 - 0.024 15.0 0.0 0.037 14.4 0.0 1.3 1 0 0 1 1 1 0 Putative vitamin uptake transporter Glyco_hydro_92 PF07971.12 KXL44986.1 - 1.6e-140 469.1 0.0 2.1e-140 468.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KXL44986.1 - 2.4e-58 197.8 3.1 3.7e-58 197.2 3.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain ELFV_dehydrog PF00208.21 KXL44987.1 - 1.8e-84 283.3 4.0 2.2e-84 283.0 4.0 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KXL44987.1 - 3.9e-53 178.8 0.0 1.2e-52 177.2 0.0 1.8 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Qn_am_d_aIV PF09100.10 KXL44987.1 - 0.0032 17.3 0.3 0.0073 16.1 0.3 1.6 1 0 0 1 1 1 1 Quinohemoprotein amine dehydrogenase, alpha subunit domain IV NAD_binding_7 PF13241.6 KXL44987.1 - 0.16 12.4 0.1 0.53 10.8 0.1 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding COX7C PF02935.16 KXL44988.1 - 2.4e-24 85.4 6.2 2.9e-24 85.1 6.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc IKI3 PF04762.12 KXL44989.1 - 3.9e-264 879.0 0.0 3e-136 455.8 0.0 2.1 1 1 1 2 2 2 2 IKI3 family ANAPC4_WD40 PF12894.7 KXL44989.1 - 0.0041 17.4 0.1 2.3 8.6 0.0 3.9 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KXL44989.1 - 0.14 11.2 0.8 0.6 9.1 0.0 2.3 2 0 0 2 2 2 0 Coatomer WD associated region SIP1 PF04938.12 KXL44990.1 - 1.5e-16 60.7 0.0 1.9e-13 50.7 0.0 2.3 2 0 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) Peptidase_M20 PF01546.28 KXL44991.1 - 1.1e-18 67.7 0.0 2.3e-18 66.6 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXL44991.1 - 1.5e-12 47.4 0.2 4e-12 46.0 0.1 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain ANTH PF07651.16 KXL44992.1 - 3.6e-77 259.1 0.0 3.6e-77 259.1 0.0 3.2 3 1 0 3 3 3 1 ANTH domain I_LWEQ PF01608.17 KXL44992.1 - 3.2e-57 193.1 7.9 3.2e-57 193.1 7.9 6.2 4 1 1 6 6 6 2 I/LWEQ domain TcdB_N PF12918.7 KXL44992.1 - 0.13 12.5 6.6 0.091 13.1 0.5 3.8 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain Focal_AT PF03623.13 KXL44992.1 - 0.81 9.7 9.3 0.23 11.5 0.4 4.0 4 1 0 4 4 4 0 Focal adhesion targeting region zf-RING_2 PF13639.6 KXL44993.1 - 2.1e-12 47.2 5.5 3.3e-12 46.5 5.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXL44993.1 - 4.1e-09 36.1 4.5 6.7e-09 35.4 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXL44993.1 - 2e-08 34.4 3.8 4.4e-08 33.3 3.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KXL44993.1 - 2.3e-08 33.8 3.8 3.8e-08 33.1 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 KXL44993.1 - 3.2e-08 33.5 0.0 1.1e-07 31.8 0.0 1.9 2 0 0 2 2 1 1 PA domain zf-RING_11 PF17123.5 KXL44993.1 - 3.1e-07 30.0 3.3 3.1e-07 30.0 3.3 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 KXL44993.1 - 5.4e-07 29.5 2.7 8.5e-07 28.8 2.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXL44993.1 - 5.9e-06 26.0 3.1 8.7e-06 25.5 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXL44993.1 - 1.1e-05 25.4 2.3 1.6e-05 24.8 0.5 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KXL44993.1 - 0.0007 19.6 0.4 0.0013 18.7 0.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KXL44993.1 - 0.0064 16.3 2.8 0.011 15.6 2.8 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KXL44993.1 - 0.028 14.0 3.0 0.053 13.2 3.0 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KXL44993.1 - 0.12 12.5 4.7 0.25 11.5 4.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KXL44993.1 - 0.16 12.1 2.6 0.42 10.8 2.6 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 KXL44993.1 - 0.37 11.0 3.4 0.73 10.0 3.2 1.7 1 1 0 1 1 1 0 RING-variant domain zf-Nse PF11789.8 KXL44993.1 - 1 9.2 2.7 2.1 8.3 2.7 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 KXL44993.1 - 1.3 9.0 2.7 2.3 8.2 2.7 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 KXL44993.1 - 1.3 9.3 3.3 2.4 8.5 3.3 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 KXL44993.1 - 1.4 8.7 2.9 2.8 7.8 2.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain MIP PF00230.20 KXL44994.1 - 1.1e-49 169.2 16.2 1.5e-49 168.8 16.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein Pyr_redox_2 PF07992.14 KXL44995.1 - 4.3e-10 39.3 0.1 5e-10 39.1 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXL44995.1 - 0.00013 22.1 0.3 0.0003 21.0 0.1 1.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXL44995.1 - 0.00022 21.7 2.9 0.0066 17.0 2.9 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXL44995.1 - 0.0005 19.4 0.3 0.00087 18.6 0.3 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXL44995.1 - 0.0014 17.8 0.2 0.002 17.3 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXL44995.1 - 0.0086 15.7 1.1 0.027 14.1 0.3 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KXL44995.1 - 0.073 11.9 0.0 0.097 11.5 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.14 KXL44995.1 - 0.091 11.4 0.6 0.13 10.9 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein RcpC PF16976.5 KXL44996.1 - 0.057 13.5 1.3 0.073 13.1 1.3 1.2 1 0 0 1 1 1 0 Flp pilus assembly protein RcpC/CpaB DDE_1 PF03184.19 KXL44997.1 - 0.033 13.8 0.0 0.033 13.8 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease SieB PF14163.6 KXL44998.1 - 0.003 17.1 0.3 0.003 17.1 0.3 1.8 3 0 0 3 3 3 1 Super-infection exclusion protein B MARVEL PF01284.23 KXL44998.1 - 0.039 14.0 19.7 0.019 15.0 14.6 2.0 1 1 1 2 2 2 0 Membrane-associating domain RT_RNaseH_2 PF17919.1 KXL44999.1 - 2.5e-21 75.6 0.2 3.1e-20 72.1 0.2 1.9 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KXL44999.1 - 8.8e-12 45.2 0.1 8.4e-11 42.1 0.1 2.0 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Sugar_tr PF00083.24 KXL45001.1 - 2.2e-66 224.6 27.6 2.6e-66 224.4 27.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL45001.1 - 2.2e-25 89.3 30.5 2.7e-16 59.5 15.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3792 PF12670.7 KXL45001.1 - 0.0085 16.3 4.8 0.0085 16.3 4.8 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3792) TMEM40 PF15817.5 KXL45001.1 - 0.18 11.6 0.2 0.18 11.6 0.2 3.3 3 0 0 3 3 3 0 Transmembrane protein 40 family Pkinase PF00069.25 KXL45002.1 - 7.8e-43 146.7 0.0 1.2e-42 146.1 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL45002.1 - 2.2e-27 96.0 0.0 1.8e-18 66.8 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXL45002.1 - 0.095 11.5 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Rpn3_C PF08375.11 KXL45003.1 - 1.1e-21 77.0 0.8 2.1e-21 76.1 0.8 1.4 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 KXL45003.1 - 1.7e-19 70.3 0.0 5e-19 68.8 0.0 1.8 1 0 0 1 1 1 1 PCI domain DASH_Spc34 PF08657.10 KXL45004.1 - 5.9e-40 137.7 4.6 8.2e-20 71.7 1.9 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 DASH_Spc19 PF08287.11 KXL45004.1 - 0.0021 18.0 4.7 0.0033 17.3 4.7 1.3 1 0 0 1 1 1 1 Spc19 GAS PF13851.6 KXL45004.1 - 0.0087 15.4 5.0 0.014 14.7 5.0 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF4140 PF13600.6 KXL45004.1 - 0.037 14.5 5.6 3.5 8.1 1.9 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Spectrin PF00435.21 KXL45004.1 - 0.078 13.5 3.2 5.9 7.4 4.1 2.4 1 1 1 2 2 2 0 Spectrin repeat Spc7 PF08317.11 KXL45004.1 - 0.11 11.3 2.8 0.17 10.7 2.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2730 PF10805.8 KXL45004.1 - 0.41 10.8 3.4 0.71 10.0 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) DUF4407 PF14362.6 KXL45004.1 - 0.44 9.8 3.8 0.53 9.6 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BBS2_C PF14782.6 KXL45004.1 - 0.82 8.4 6.1 2.5 6.8 2.4 2.0 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal DUF3287 PF11690.8 KXL45004.1 - 1.8 8.3 5.8 0.84 9.4 0.8 2.4 2 1 0 3 3 3 0 Protein of unknown function (DUF3287) PfkB PF00294.24 KXL45005.1 - 6.7e-12 45.3 0.0 1.3e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase F-box-like PF12937.7 KXL45006.1 - 1.9e-06 27.6 0.4 5.3e-06 26.2 0.4 1.7 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 KXL45006.1 - 2.4e-05 24.0 4.2 0.02 14.9 0.0 4.3 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 KXL45006.1 - 0.0019 18.5 5.7 16 6.1 0.4 5.1 3 1 2 5 5 5 2 Leucine Rich repeats (2 copies) F-box PF00646.33 KXL45006.1 - 0.07 13.0 0.2 0.37 10.7 0.2 2.2 1 0 0 1 1 1 0 F-box domain LRR_8 PF13855.6 KXL45006.1 - 0.3 10.9 7.3 0.84 9.4 0.3 4.1 3 1 1 4 4 4 0 Leucine rich repeat GMC_oxred_C PF05199.13 KXL45007.1 - 2e-15 57.6 0.1 2.3e-15 57.4 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KXL45008.1 - 2e-69 234.2 0.0 2.5e-69 233.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXL45008.1 - 3.8e-05 23.0 0.4 0.003 16.7 0.4 2.6 3 0 0 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.12 KXL45008.1 - 3.9e-05 22.9 0.0 5.6e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KXL45008.1 - 0.00013 21.3 0.1 0.00027 20.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KXL45008.1 - 0.00032 20.9 0.3 0.0011 19.1 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXL45008.1 - 0.00052 19.7 0.3 0.0015 18.2 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXL45008.1 - 0.02 14.1 0.0 0.073 12.3 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXL45008.1 - 0.067 12.4 0.2 0.59 9.3 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXL45008.1 - 0.07 11.8 0.1 0.07 11.8 0.1 1.5 2 0 0 2 2 2 0 HI0933-like protein RrnaAD PF00398.20 KXL45009.1 - 9.7e-61 205.1 0.1 2e-60 204.1 0.0 1.5 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KXL45009.1 - 3.7e-07 30.8 0.0 8.4e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL45009.1 - 8e-05 23.2 0.0 0.0002 22.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL45009.1 - 0.00066 20.4 0.0 0.0017 19.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL45009.1 - 0.00071 19.4 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXL45009.1 - 0.00092 19.0 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PRMT5 PF05185.16 KXL45009.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_23 PF13489.6 KXL45009.1 - 0.013 15.3 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KXL45009.1 - 0.018 14.6 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain AAA_lid_4 PF17864.1 KXL45009.1 - 0.069 12.9 0.6 0.19 11.5 0.1 1.9 2 0 0 2 2 2 0 RuvB AAA lid domain Met_10 PF02475.16 KXL45009.1 - 0.089 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein CMAS PF02353.20 KXL45009.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase WD40 PF00400.32 KXL45010.1 - 4.4e-34 115.9 21.6 0.00015 22.5 0.4 11.1 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL45010.1 - 5.9e-19 68.2 2.9 1.6e-05 25.1 0.0 7.2 4 3 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXL45010.1 - 7.1e-05 22.8 1.9 0.63 9.9 0.2 4.9 2 2 3 5 5 5 1 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.6 KXL45010.1 - 0.00018 21.5 0.1 0.012 15.7 0.0 3.2 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region PD40 PF07676.12 KXL45010.1 - 0.0012 18.7 3.7 0.23 11.5 0.0 4.9 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 KXL45010.1 - 0.0013 19.1 1.9 30 5.3 0.0 5.5 5 0 0 5 5 5 0 PQQ-like domain Ge1_WD40 PF16529.5 KXL45010.1 - 0.0016 17.5 6.0 0.65 8.9 0.3 5.2 3 2 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Me-amine-dh_H PF06433.11 KXL45010.1 - 0.014 14.3 0.0 0.048 12.5 0.0 2.0 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) Hira PF07569.11 KXL45010.1 - 0.028 14.1 0.2 0.14 11.8 0.1 2.1 2 0 0 2 2 2 0 TUP1-like enhancer of split DBP10CT PF08147.12 KXL45010.1 - 0.18 12.1 0.5 2.9 8.2 0.2 2.6 2 0 0 2 2 2 0 DBP10CT (NUC160) domain AA_permease_2 PF13520.6 KXL45011.1 - 5.6e-53 180.3 48.9 6.9e-53 180.0 48.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXL45011.1 - 1.8e-16 59.8 37.8 2.4e-16 59.4 37.8 1.1 1 0 0 1 1 1 1 Amino acid permease PsbY PF06298.11 KXL45012.1 - 0.36 10.8 3.4 1.1 9.2 3.4 1.8 1 0 0 1 1 1 0 Photosystem II protein Y (PsbY) AP_endonuc_2 PF01261.24 KXL45013.1 - 4.9e-32 111.1 0.3 6.6e-32 110.7 0.3 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel AbfB PF05270.13 KXL45015.1 - 0.09 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Alpha-L-arabinofuranosidase B (ABFB) domain Hep_59 PF07052.11 KXL45017.1 - 2.6e-05 24.9 0.2 2.6e-05 24.9 0.2 2.2 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 GFO_IDH_MocA PF01408.22 KXL45019.1 - 4.8e-24 85.5 0.2 3.5e-23 82.7 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KXL45019.1 - 0.068 13.8 0.0 0.12 13.0 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Thioredoxin_2 PF13098.6 KXL45019.1 - 0.08 13.4 0.1 0.16 12.5 0.1 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain TPR_2 PF07719.17 KXL45020.1 - 4.1e-08 32.7 6.7 0.0047 16.9 0.3 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXL45020.1 - 1.6e-07 30.9 8.8 0.0027 17.5 0.3 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXL45020.1 - 1.1e-05 25.9 7.0 0.00053 20.4 2.3 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXL45020.1 - 0.0024 18.1 2.3 2.5 8.7 0.6 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXL45020.1 - 0.0031 17.7 3.9 0.011 16.0 0.4 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXL45020.1 - 0.011 16.5 8.7 0.038 14.8 2.2 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXL45020.1 - 0.043 13.9 4.6 0.85 9.7 0.1 3.7 3 1 1 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Pox_T4_N PF04491.12 KXL45020.1 - 0.065 13.1 0.3 0.49 10.3 0.0 2.5 3 0 0 3 3 3 0 Poxvirus T4 protein, N terminus ANAPC3 PF12895.7 KXL45020.1 - 0.072 13.3 3.4 0.065 13.5 1.2 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KXL45020.1 - 0.089 12.9 0.1 2.2 8.5 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KXL45020.1 - 0.18 11.5 3.8 7 6.4 0.1 3.3 2 1 1 3 3 3 0 TPR repeat PHP_C PF13263.6 KXL45020.1 - 0.18 11.6 0.8 0.9 9.3 0.5 2.4 2 0 0 2 2 2 0 PHP-associated TPR_8 PF13181.6 KXL45020.1 - 0.36 11.1 3.6 6.4 7.3 0.1 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat Mcp5_PH PF12814.7 KXL45021.1 - 1.2e-42 144.8 0.1 2.4e-42 143.9 0.1 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Fez1 PF06818.15 KXL45021.1 - 0.00042 20.8 15.5 0.00091 19.7 15.5 1.5 1 0 0 1 1 1 1 Fez1 TPR_MLP1_2 PF07926.12 KXL45021.1 - 0.021 14.9 22.0 0.02 15.0 19.2 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3584 PF12128.8 KXL45021.1 - 0.48 7.9 15.6 0.68 7.4 15.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FlaC_arch PF05377.11 KXL45021.1 - 0.54 10.7 1.4 1.3 9.5 1.4 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Exonuc_VII_L PF02601.15 KXL45021.1 - 0.55 9.8 10.6 1.1 8.8 10.6 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Macoilin PF09726.9 KXL45021.1 - 0.83 8.1 14.5 2 6.9 14.5 1.6 1 0 0 1 1 1 0 Macoilin family Jnk-SapK_ap_N PF09744.9 KXL45021.1 - 4.7 7.4 22.9 0.95 9.7 9.2 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Drc1-Sld2 PF11719.8 KXL45022.1 - 9.7e-74 249.5 20.9 1.1e-73 249.3 20.9 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein DUF4456 PF14644.6 KXL45022.1 - 0.32 10.6 2.5 8 6.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4456) DOPA_dioxygen PF08883.11 KXL45023.1 - 2.3e-43 146.7 0.0 2.8e-43 146.4 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family ubiquitin PF00240.23 KXL45024.1 - 4.6e-34 116.0 0.6 7.9e-34 115.2 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 KXL45024.1 - 3.5e-26 91.1 2.3 3.5e-26 91.1 2.3 2.0 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 KXL45024.1 - 2.6e-16 59.2 0.7 4.9e-16 58.3 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KXL45024.1 - 2.7e-05 24.5 0.3 0.00013 22.4 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KXL45024.1 - 0.0012 19.0 0.6 0.0026 17.8 0.6 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KXL45024.1 - 0.004 17.5 0.6 0.0079 16.5 0.0 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KXL45024.1 - 0.0055 16.6 0.0 0.0082 16.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 KXL45024.1 - 0.013 16.1 0.7 0.019 15.6 0.7 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KXL45024.1 - 0.021 14.9 1.0 5.9 7.0 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain zf-C2H2 PF00096.26 KXL45025.1 - 4.6e-15 55.1 8.6 8.1e-07 29.2 1.2 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXL45025.1 - 8.1e-11 41.8 7.8 3e-05 24.5 0.9 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXL45025.1 - 2.2e-10 40.5 6.0 1.4e-06 28.5 0.1 3.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KXL45025.1 - 1.8e-07 31.3 5.1 0.00019 21.7 1.0 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KXL45025.1 - 1.3e-05 25.1 1.7 0.0019 18.1 0.2 3.1 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.7 KXL45025.1 - 0.00027 21.2 4.3 0.0087 16.4 0.3 2.9 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KXL45025.1 - 0.0074 16.6 0.1 0.0089 16.3 0.1 1.2 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf_ZIC PF18366.1 KXL45025.1 - 0.0083 16.2 1.5 0.16 12.1 0.5 2.3 1 1 1 2 2 2 1 Zic proteins zinc finger domain zf-BED PF02892.15 KXL45025.1 - 0.03 14.3 0.6 2.5 8.2 0.1 2.3 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_5 PF13909.6 KXL45025.1 - 0.034 13.9 9.7 0.048 13.4 3.1 3.0 3 1 0 3 3 3 0 C2H2-type zinc-finger domain PAP2_3 PF14378.6 KXL45027.1 - 2.7e-22 79.4 11.4 2.7e-22 79.4 11.4 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 KXL45027.1 - 4.6e-09 36.2 4.4 4.6e-09 36.2 4.4 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 KXL45027.1 - 6.2 7.4 9.3 0.53 10.9 3.7 2.2 2 1 1 3 3 3 0 PAP2 superfamily C-terminal Ribosomal_L11_N PF03946.14 KXL45028.1 - 1.5e-25 88.8 0.5 2.7e-25 88.0 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KXL45028.1 - 7.8e-23 80.8 1.9 2.7e-22 79.0 1.9 1.8 1 1 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Cep57_MT_bd PF06657.13 KXL45029.1 - 0.03 14.8 0.1 0.052 14.0 0.1 1.3 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DUF3995 PF13160.6 KXL45029.1 - 0.19 12.1 7.0 0.18 12.2 5.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3995) CSN8_PSD8_EIF3K PF10075.9 KXL45030.1 - 9.1e-20 71.1 0.0 1.4e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 KXL45030.1 - 0.00016 21.2 0.0 0.00028 20.4 0.0 1.4 2 0 0 2 2 2 1 SAC3/GANP family DUF2582 PF10771.9 KXL45030.1 - 0.12 12.5 0.0 0.37 11.0 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix domain (DUF2582) CSTF2_hinge PF14327.6 KXL45030.1 - 0.56 10.7 3.6 1.2 9.7 3.6 1.5 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 KXL45032.1 - 5.8e-56 186.2 0.0 4.2e-19 68.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KXL45032.1 - 2.4e-06 27.5 0.0 0.067 13.3 0.0 3.9 3 2 0 3 3 3 2 Limkain b1 RRM_occluded PF16842.5 KXL45032.1 - 0.0025 17.7 0.0 0.52 10.2 0.0 2.9 3 0 0 3 3 3 1 Occluded RNA-recognition motif PknH_C PF14032.6 KXL45032.1 - 0.067 13.1 0.1 43 3.9 0.1 3.1 3 0 0 3 3 3 0 PknH-like extracellular domain RRM_5 PF13893.6 KXL45032.1 - 0.087 12.4 0.0 2.7 7.6 0.0 2.6 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3343 PF11823.8 KXL45032.1 - 0.18 11.3 0.0 0.61 9.6 0.0 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3343) RRM_Rrp7 PF17799.1 KXL45032.1 - 0.26 11.1 0.0 7.2 6.4 0.0 2.6 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain Mito_carr PF00153.27 KXL45033.1 - 6.2e-40 135.0 1.7 2.9e-14 52.7 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Rab5ip PF07019.12 KXL45033.1 - 0.02 15.5 2.2 0.075 13.6 0.0 2.8 2 1 1 3 3 3 0 Rab5-interacting protein (Rab5ip) NYN PF01936.18 KXL45034.1 - 0.00015 22.3 0.0 0.00052 20.5 0.0 1.8 1 1 0 1 1 1 1 NYN domain DUF2855 PF11017.8 KXL45035.1 - 6.4e-11 42.6 0.0 7.1e-11 42.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) DUF2681 PF10883.8 KXL45037.1 - 0.042 14.2 0.0 0.061 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) UcrQ PF02939.16 KXL45037.1 - 0.061 13.3 0.1 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 UcrQ family GAD-like PF08887.11 KXL45037.1 - 0.1 12.4 0.0 0.13 12.1 0.0 1.3 1 1 0 1 1 1 0 GAD-like domain Transport_MerF PF11431.8 KXL45037.1 - 0.14 12.0 1.8 0.22 11.4 1.8 1.3 1 0 0 1 1 1 0 Membrane transport protein MerF Gti1_Pac2 PF09729.9 KXL45038.1 - 8.3e-43 146.6 0.6 3.4e-39 134.8 0.3 2.0 1 1 1 2 2 2 2 Gti1/Pac2 family MFS_1 PF07690.16 KXL45040.1 - 2.3e-37 128.7 43.5 4.2e-37 127.9 43.5 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXL45040.1 - 1.2e-10 40.5 22.7 1.8e-10 39.9 22.7 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Alpha-amylase PF00128.24 KXL45042.1 - 1.9e-59 201.9 0.1 2.8e-59 201.4 0.1 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain CBM_20 PF00686.19 KXL45042.1 - 1.5e-30 104.9 0.5 3.9e-30 103.6 0.5 1.8 1 0 0 1 1 1 1 Starch binding domain DUF1966 PF09260.11 KXL45042.1 - 5.7e-26 90.6 0.4 1.2e-25 89.6 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) DUF1688 PF07958.11 KXL45044.1 - 1e-184 614.2 0.0 1.1e-184 614.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) SPX PF03105.19 KXL45046.1 - 1.8e-19 70.9 0.0 2.1e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 SPX domain Abhydrolase_6 PF12697.7 KXL45047.1 - 9.2e-15 55.8 0.0 1.2e-14 55.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXL45047.1 - 1.3e-13 51.2 0.0 1.5e-13 51.0 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXL45047.1 - 2.7e-10 39.9 0.0 1.2e-09 37.9 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KXL45047.1 - 5.9e-07 29.5 0.0 8.5e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.13 KXL45047.1 - 1.2e-05 25.3 0.0 7.3e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KXL45047.1 - 4.1e-05 22.6 0.0 5.2e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KXL45047.1 - 0.0021 17.2 0.0 0.0029 16.7 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Ser_hydrolase PF06821.13 KXL45047.1 - 0.014 15.2 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase DUF1749 PF08538.10 KXL45047.1 - 0.024 13.7 0.0 0.031 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) LIDHydrolase PF10230.9 KXL45047.1 - 0.05 13.2 0.0 0.072 12.6 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF900 PF05990.12 KXL45047.1 - 0.13 11.8 0.0 0.2 11.1 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) COesterase PF00135.28 KXL45047.1 - 0.15 10.9 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family PGC7_Stella PF15549.6 KXL45047.1 - 0.16 12.0 0.2 0.62 10.0 0.1 1.8 1 1 1 2 2 2 0 PGC7/Stella/Dppa3 domain Abhydrolase_5 PF12695.7 KXL45047.1 - 0.17 11.6 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Voldacs PF03517.13 KXL45048.1 - 1e-15 58.0 4.1 3.2e-13 50.0 4.1 2.6 1 1 0 1 1 1 1 Regulator of volume decrease after cellular swelling DUF2201_N PF13203.6 KXL45048.1 - 0.1 12.2 0.3 0.33 10.5 0.0 1.8 2 0 0 2 2 2 0 Putative metallopeptidase domain Menin PF05053.13 KXL45049.1 - 0.23 9.8 0.4 0.35 9.2 0.4 1.2 1 0 0 1 1 1 0 Menin adh_short_C2 PF13561.6 KXL45050.1 - 1e-58 198.7 1.5 8.6e-58 195.7 1.5 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL45050.1 - 1.9e-33 115.6 1.7 6.9e-33 113.7 1.7 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL45050.1 - 2.5e-08 34.0 1.3 1.9e-07 31.2 0.1 2.1 2 0 0 2 2 2 1 KR domain 3HCDH_N PF02737.18 KXL45050.1 - 0.012 15.5 0.4 0.24 11.2 0.2 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 KXL45050.1 - 0.018 14.5 0.1 0.19 11.1 0.1 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 KXL45050.1 - 0.051 12.9 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KXL45051.1 - 1.3e-20 74.4 0.2 2.2e-20 73.6 0.2 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold AMP-binding PF00501.28 KXL45052.1 - 6.7e-45 153.4 0.0 9.5e-45 152.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KXL45052.1 - 2.1e-05 24.3 0.8 5.5e-05 23.0 0.8 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus TIR PF01582.20 KXL45052.1 - 0.034 13.9 0.3 0.076 12.8 0.3 1.5 1 0 0 1 1 1 0 TIR domain PhoD PF09423.10 KXL45054.1 - 3.3e-45 154.6 0.0 5.6e-45 153.9 0.0 1.3 1 0 0 1 1 1 1 PhoD-like phosphatase Pur_ac_phosph_N PF16656.5 KXL45054.1 - 0.047 14.3 0.0 0.17 12.4 0.0 1.9 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain Glyco_hydro_28 PF00295.17 KXL45055.1 - 4.8e-29 101.5 5.3 6.3e-29 101.1 5.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 KXL45055.1 - 1e-05 25.5 15.5 1.7e-05 24.7 3.9 3.2 1 1 1 2 2 2 1 Pectate lyase superfamily protein HET PF06985.11 KXL45056.1 - 4.7e-27 95.1 1.7 7.6e-27 94.5 0.2 2.1 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 KXL45057.1 - 8.2e-42 143.4 0.0 3.5e-41 141.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL45057.1 - 8.2e-32 110.5 0.0 1.1e-31 110.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXL45057.1 - 0.00059 19.2 0.0 0.00099 18.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXL45057.1 - 0.14 11.5 0.1 0.24 10.7 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SPX PF03105.19 KXL45057.1 - 3.2 7.6 5.2 1.9 8.3 2.5 1.8 2 0 0 2 2 2 0 SPX domain zf-Tim10_DDP PF02953.15 KXL45059.1 - 5.4 6.7 7.9 39 4.0 2.9 3.1 2 1 0 2 2 2 0 Tim10/DDP family zinc finger zf-C2H2_jaz PF12171.8 KXL45060.1 - 0.00056 20.1 0.2 0.001 19.3 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXL45060.1 - 0.0027 18.0 0.5 0.0052 17.1 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KXL45060.1 - 0.056 13.8 0.1 0.16 12.3 0.1 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Fzo_mitofusin PF04799.13 KXL45060.1 - 0.23 11.0 1.5 0.45 10.1 1.5 1.6 1 0 0 1 1 1 0 fzo-like conserved region DUF5423 PF17461.2 KXL45060.1 - 0.38 9.6 4.7 0.76 8.6 4.7 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5423) ATG16 PF08614.11 KXL45061.1 - 0.0043 17.3 30.0 0.0043 17.3 30.0 9.7 2 2 5 7 7 7 2 Autophagy protein 16 (ATG16) Golgin_A5 PF09787.9 KXL45061.1 - 0.0044 16.5 16.2 0.0044 16.5 16.2 7.2 1 1 6 7 7 7 2 Golgin subfamily A member 5 TMF_DNA_bd PF12329.8 KXL45061.1 - 0.0066 16.4 6.4 0.0066 16.4 6.4 14.4 4 3 10 15 15 15 7 TATA element modulatory factor 1 DNA binding Filament PF00038.21 KXL45061.1 - 0.062 12.9 158.4 0.014 15.0 24.5 7.0 2 1 4 6 6 6 0 Intermediate filament protein VHS PF00790.19 KXL45062.1 - 3.4e-27 95.0 0.0 6.6e-27 94.1 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KXL45062.1 - 3.5e-06 27.2 0.3 7.7e-06 26.1 0.3 1.6 1 0 0 1 1 1 1 GAT domain Prenyltrans PF00432.21 KXL45063.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat Hexapep PF00132.24 KXL45065.1 - 2.1e-11 43.1 13.7 0.00014 21.4 0.8 4.6 2 1 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 KXL45065.1 - 1.9e-07 30.9 0.0 3.2e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KXL45065.1 - 5.4e-05 23.6 0.0 0.00013 22.3 0.0 1.7 2 0 0 2 2 2 1 MobA-like NTP transferase domain DUF4954 PF16314.5 KXL45065.1 - 0.0061 14.8 2.3 0.01 14.0 0.4 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 KXL45065.1 - 0.0067 16.2 9.3 1.8 8.4 0.9 3.8 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KXL45065.1 - 0.052 12.5 0.4 0.16 10.8 0.4 1.8 1 1 0 1 1 1 0 L-fucokinase HSF_DNA-bind PF00447.17 KXL45066.1 - 4.3e-31 107.4 0.8 8.2e-31 106.5 0.8 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 KXL45066.1 - 3.7e-22 78.6 0.0 6.9e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Redoxin PF08534.10 KXL45067.1 - 2.6e-26 92.1 0.0 3.1e-26 91.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KXL45067.1 - 1.9e-07 31.1 0.0 2.4e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family IBR PF01485.21 KXL45069.1 - 9.6e-21 73.8 53.2 1.8e-11 44.1 8.4 4.9 4 1 1 5 5 5 3 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KXL45069.1 - 7.2e-05 23.0 4.3 7.2e-05 23.0 4.3 4.3 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.25 KXL45069.1 - 0.00011 21.9 4.9 0.00011 21.9 4.9 5.1 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXL45069.1 - 0.003 17.4 4.8 0.003 17.4 4.8 5.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXL45069.1 - 0.01 15.8 4.4 0.01 15.8 4.4 3.8 3 1 0 3 3 3 0 RING-type zinc-finger UN_NPL4 PF11543.8 KXL45069.1 - 0.011 16.2 0.0 0.023 15.2 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 zf-C3HC4_4 PF15227.6 KXL45069.1 - 0.031 14.4 0.5 0.031 14.4 0.5 4.6 4 1 0 4 4 4 0 zinc finger of C3HC4-type, RING adh_short PF00106.25 KXL45070.1 - 1.1e-06 28.2 0.0 1.8e-06 27.6 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL45070.1 - 1e-05 25.2 0.0 1.3e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KXL45070.1 - 0.029 13.8 0.0 0.034 13.6 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KXL45070.1 - 0.052 13.4 0.1 0.088 12.7 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DDE_1 PF03184.19 KXL45071.1 - 6.6e-13 48.7 0.0 8e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease RNA12 PF10443.9 KXL45073.1 - 1.1e-167 558.3 0.5 1.1e-167 558.3 0.5 1.6 2 0 0 2 2 2 1 RNA12 protein ATPase_2 PF01637.18 KXL45073.1 - 2.3e-06 27.7 0.0 1.4e-05 25.2 0.0 2.2 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea RRM_1 PF00076.22 KXL45073.1 - 2.7e-05 23.9 0.0 9e-05 22.2 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.6 KXL45073.1 - 0.0034 17.8 1.3 0.013 15.9 0.1 2.5 2 1 1 3 3 3 1 AAA ATPase domain DUF2487 PF10673.9 KXL45073.1 - 0.0049 16.9 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2487) DBD_Tnp_Hermes PF10683.9 KXL45073.1 - 0.067 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain TIP49 PF06068.13 KXL45074.1 - 6.3e-145 482.8 0.0 7.7e-145 482.5 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KXL45074.1 - 7.1e-22 77.3 0.2 1.8e-21 76.0 0.2 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain RuvB_N PF05496.12 KXL45074.1 - 2.4e-08 33.9 0.2 5.9e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 KXL45074.1 - 9.5e-08 32.5 0.1 7.9e-05 23.1 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXL45074.1 - 9.9e-05 22.8 1.0 0.0008 19.8 1.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 KXL45074.1 - 0.0051 16.2 0.7 0.27 10.6 0.2 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KXL45074.1 - 0.012 15.9 0.1 0.068 13.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 KXL45074.1 - 0.019 14.3 0.2 0.032 13.6 0.2 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Sigma54_activat PF00158.26 KXL45074.1 - 0.034 13.9 0.1 8.7 6.0 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.14 KXL45074.1 - 0.058 13.4 0.1 13 5.8 0.0 2.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXL45074.1 - 0.083 13.2 0.2 3.5 7.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KXL45074.1 - 0.11 12.2 0.3 0.27 11.0 0.3 1.7 1 1 0 1 1 1 0 AAA domain AAA_32 PF13654.6 KXL45074.1 - 0.12 11.2 0.1 0.3 9.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain SlyX PF04102.12 KXL45075.1 - 0.00019 22.0 22.0 0.32 11.7 0.2 8.5 9 1 1 10 10 10 2 SlyX DUF365 PF04033.12 KXL45075.1 - 0.011 15.9 0.1 0.047 14.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF365) DUF4677 PF15726.5 KXL45075.1 - 0.012 15.8 0.1 0.041 14.0 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4677) DUF1664 PF07889.12 KXL45075.1 - 0.014 15.4 0.3 0.014 15.4 0.3 9.2 7 2 4 12 12 12 0 Protein of unknown function (DUF1664) SOG2 PF10428.9 KXL45075.1 - 0.11 11.7 0.1 0.11 11.7 0.1 3.6 2 1 1 3 3 3 0 RAM signalling pathway protein NPV_P10 PF05531.12 KXL45075.1 - 0.48 10.9 36.8 2.4 8.7 1.2 10.0 5 4 4 9 9 9 0 Nucleopolyhedrovirus P10 protein AKNA PF12443.8 KXL45075.1 - 2.3 9.0 9.4 4 8.2 0.0 5.5 6 1 0 6 6 6 0 AT-hook-containing transcription factor Rx_N PF18052.1 KXL45075.1 - 5.4 7.4 13.6 4.7 7.5 0.1 4.7 3 2 1 4 4 4 0 Rx N-terminal domain DUF4061 PF13270.6 KXL45075.1 - 6.6 7.1 9.4 0.86 10.0 0.1 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4061) Cnn_1N PF07989.11 KXL45075.1 - 9.2 6.5 22.6 6.7 7.0 0.5 6.6 5 0 0 5 5 5 0 Centrosomin N-terminal motif 1 WLM PF08325.10 KXL45076.1 - 7.1e-52 176.3 0.0 1.1e-51 175.6 0.0 1.3 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 KXL45076.1 - 0.013 15.5 1.3 0.026 14.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF45 SprT-like PF10263.9 KXL45076.1 - 0.026 14.4 0.1 0.049 13.5 0.1 1.5 1 0 0 1 1 1 0 SprT-like family MARVEL PF01284.23 KXL45077.1 - 9.4e-20 71.1 22.0 1.2e-19 70.8 22.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain T2SSM PF04612.12 KXL45077.1 - 0.18 11.9 0.5 0.31 11.1 0.5 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M DHHC PF01529.20 KXL45077.1 - 3.2 7.9 7.7 4.2 7.5 7.0 1.7 1 1 0 1 1 1 0 DHHC palmitoyltransferase AMP-binding PF00501.28 KXL45079.1 - 2e-90 303.5 0.0 2.4e-90 303.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Cys_Met_Meta_PP PF01053.20 KXL45080.1 - 8e-133 442.7 0.0 1.6e-125 418.6 0.0 2.0 1 1 1 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KXL45080.1 - 3.8e-09 36.0 0.1 7.3e-09 35.0 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KXL45080.1 - 2e-08 33.8 0.0 3e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KXL45080.1 - 6.4e-05 22.4 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KXL45080.1 - 0.0011 18.3 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 KXL45080.1 - 0.0015 17.2 0.0 0.002 16.7 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase Asparaginase_C PF17763.1 KXL45080.1 - 0.0036 17.5 0.1 0.01 16.0 0.0 1.8 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain CPSase_L_D2 PF02786.17 KXL45080.1 - 0.081 12.4 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain TRAPPC10 PF12584.8 KXL45081.1 - 6.7e-26 90.9 0.0 1.1e-25 90.1 0.0 1.4 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gryzun-like PF12742.7 KXL45081.1 - 0.0019 18.1 0.1 0.033 14.2 0.1 2.6 2 0 0 2 2 2 1 Gryzun, putative Golgi trafficking QCR10 PF09796.9 KXL45082.1 - 9.6e-27 92.8 0.4 1.2e-26 92.5 0.4 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DUF1013 PF06242.11 KXL45083.1 - 0.024 14.7 0.1 1.3 9.1 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1013) Preseq_ALAS PF09029.10 KXL45083.1 - 1.4 9.5 8.4 1.6e+02 2.7 8.4 2.8 1 1 0 1 1 1 0 5-aminolevulinate synthase presequence Na_H_Exchanger PF00999.21 KXL45084.1 - 1.6e-43 149.0 17.4 2e-43 148.6 17.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family adh_short_C2 PF13561.6 KXL45085.1 - 3e-53 180.8 3.8 1.4e-30 106.6 1.2 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL45085.1 - 1.9e-38 131.9 6.5 2.8e-31 108.5 4.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase 3HCDH_N PF02737.18 KXL45085.1 - 0.041 13.8 1.4 0.1 12.5 1.4 1.7 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TIG PF01833.24 KXL45087.1 - 4.4e-11 42.7 0.7 2.2e-10 40.5 0.4 2.4 2 0 0 2 2 2 1 IPT/TIG domain SseC PF04888.12 KXL45087.1 - 0.32 10.5 1.9 0.51 9.9 1.9 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family CTNNBL PF08216.11 KXL45089.1 - 6e-37 126.0 0.3 2.1e-36 124.2 0.0 2.1 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.23 KXL45089.1 - 0.0021 18.0 0.1 0.089 12.9 0.0 3.0 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 KXL45089.1 - 0.0056 16.2 0.4 0.016 14.8 0.4 1.8 1 0 0 1 1 1 1 Atypical Arm repeat Mo25 PF08569.11 KXL45089.1 - 0.081 12.3 2.8 0.1 12.0 1.7 1.6 1 1 0 1 1 1 0 Mo25-like MMS19_C PF12460.8 KXL45089.1 - 0.1 11.7 4.3 7.6 5.5 0.2 3.2 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal IBN_N PF03810.19 KXL45090.1 - 4.6e-12 45.7 0.1 1.8e-11 43.8 0.1 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KXL45090.1 - 1.2e-05 25.4 0.1 0.0021 18.1 0.0 3.3 3 0 0 3 3 3 1 Exportin 1-like protein CAS_CSE1 PF03378.15 KXL45090.1 - 0.00025 19.7 0.0 0.0007 18.2 0.0 1.7 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus RIX1 PF08167.12 KXL45090.1 - 0.0019 18.0 0.0 0.037 13.8 0.0 3.0 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis DUF3601 PF12208.8 KXL45090.1 - 0.045 13.9 0.2 0.19 11.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3601) HORMA PF02301.18 KXL45091.1 - 4e-09 36.4 0.0 5.3e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 HORMA domain Asp PF00026.23 KXL45092.1 - 2.2e-45 155.5 0.0 3.9e-45 154.6 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KXL45092.1 - 2.9e-05 24.6 0.0 0.3 11.7 0.0 3.7 4 0 0 4 4 4 2 Aspartyl protease TAXi_C PF14541.6 KXL45092.1 - 0.011 15.5 0.0 2.2 8.0 0.0 3.0 3 0 0 3 3 3 0 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KXL45092.1 - 0.013 16.0 0.0 3.1 8.4 0.0 2.8 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease Nudc_N PF14050.6 KXL45092.1 - 0.033 14.2 0.0 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 N-terminal conserved domain of Nudc. TAXi_N PF14543.6 KXL45092.1 - 0.08 13.2 0.4 1.5 9.0 0.1 2.9 3 1 0 3 3 3 0 Xylanase inhibitor N-terminal Het-C PF07217.11 KXL45093.1 - 5.2e-265 880.3 0.0 6.5e-265 880.0 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C BSMAP PF12280.8 KXL45095.1 - 0.0096 16.1 10.1 4 7.6 10.3 3.1 3 0 0 3 3 3 1 Brain specific membrane anchored protein DDHD PF02862.17 KXL45095.1 - 0.17 12.0 11.2 0.53 10.4 11.2 1.8 1 0 0 1 1 1 0 DDHD domain PA26 PF04636.13 KXL45095.1 - 0.37 9.7 12.6 0.73 8.7 12.6 1.4 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) TFIIA PF03153.13 KXL45095.1 - 0.46 10.4 23.4 1 9.3 23.4 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 KXL45095.1 - 0.72 10.9 10.3 2.3 9.2 10.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 KXL45095.1 - 0.9 9.1 27.1 2 8.0 27.1 1.5 1 0 0 1 1 1 0 Spt20 family Activator_LAG-3 PF11498.8 KXL45095.1 - 1.2 8.0 39.0 1.9 7.4 39.0 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 RR_TM4-6 PF06459.12 KXL45095.1 - 2 8.2 18.7 2.5 7.9 15.5 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 AIF_C PF14721.6 KXL45095.1 - 6.3 7.2 7.8 15 5.9 7.8 1.7 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Afi1 PF07792.12 KXL45095.1 - 6.6 7.2 15.1 4.6 7.7 12.6 1.9 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Presenilin PF01080.17 KXL45095.1 - 9.6 4.9 14.6 16 4.1 14.6 1.3 1 0 0 1 1 1 0 Presenilin DUF924 PF06041.11 KXL45096.1 - 2.2e-38 132.2 0.2 3e-38 131.8 0.2 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Aldedh PF00171.22 KXL45097.1 - 1.7e-186 620.3 0.6 1.9e-186 620.1 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KXL45097.1 - 0.023 14.1 0.1 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) RRM_1 PF00076.22 KXL45098.1 - 1e-14 54.1 0.0 2.1e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KXL45098.1 - 7.6e-05 23.2 2.1 7.6e-05 23.2 2.1 3.3 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 KXL45098.1 - 0.00037 20.3 0.0 0.00074 19.3 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif PAP2 PF01569.21 KXL45099.1 - 8.3e-20 70.9 6.2 2.4e-19 69.5 6.2 1.8 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 KXL45099.1 - 0.02 14.6 5.5 0.041 13.6 5.5 1.6 1 0 0 1 1 1 0 PAP2 superfamily Ras PF00071.22 KXL45100.1 - 4.7e-48 162.8 0.0 6e-48 162.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXL45100.1 - 1.8e-20 73.3 0.0 3.2e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXL45100.1 - 3.4e-05 23.4 0.0 6e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 KXL45100.1 - 0.026 14.1 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 KXL45100.1 - 0.045 13.2 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF2722 PF10846.8 KXL45101.1 - 0.0018 17.3 0.1 0.0018 17.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) PRIMA1 PF16101.5 KXL45102.1 - 0.28 11.2 4.0 0.35 10.9 4.0 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 KXL45102.1 - 3 7.2 4.5 3.4 7.1 4.5 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RVT_1 PF00078.27 KXL45103.1 - 0.03 13.8 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) TPMT PF05724.11 KXL45104.1 - 6.2e-28 98.0 0.0 9e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 KXL45104.1 - 2.4e-11 44.2 0.0 3.7e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL45104.1 - 2.7e-11 44.0 0.0 4.1e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL45104.1 - 1.5e-09 38.5 0.0 3.1e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL45104.1 - 2e-09 37.4 0.0 4.4e-09 36.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXL45104.1 - 5.7e-09 36.0 0.0 7.5e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 KXL45104.1 - 0.016 15.6 0.0 0.074 13.4 0.0 2.0 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase N2227 PF07942.12 KXL45104.1 - 0.12 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 N2227-like protein DUF3368 PF11848.8 KXL45105.1 - 0.061 13.1 0.2 0.14 12.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3368) Pkinase PF00069.25 KXL45110.1 - 3.6e-49 167.5 0.0 2.4e-46 158.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXL45110.1 - 6.5e-28 97.7 0.0 1.4e-26 93.4 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KXL45110.1 - 0.00047 19.6 0.0 0.00072 19.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KXL45110.1 - 0.0029 16.7 0.1 0.0047 16.0 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 KXL45110.1 - 0.13 11.0 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase HTH_psq PF05225.16 KXL45111.1 - 6.7e-07 28.9 0.2 8.1e-07 28.7 0.2 1.1 1 0 0 1 1 1 1 helix-turn-helix, Psq domain CENP-B_N PF04218.13 KXL45111.1 - 0.015 14.9 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain NUMOD1 PF07453.13 KXL45111.1 - 0.052 13.8 0.0 0.12 12.7 0.0 1.8 1 1 0 1 1 1 0 NUMOD1 domain NEL PF14496.6 KXL45112.1 - 0.084 12.3 0.0 0.096 12.1 0.0 1.1 1 0 0 1 1 1 0 C-terminal novel E3 ligase, LRR-interacting HTH_psq PF05225.16 KXL45113.1 - 0.015 15.0 0.1 0.027 14.2 0.1 1.6 1 0 0 1 1 1 0 helix-turn-helix, Psq domain MLVIN_C PF18697.1 KXL45114.1 - 0.041 14.0 0.0 0.099 12.8 0.0 1.7 2 1 0 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Sugar_tr PF00083.24 KXL45117.1 - 2.7e-75 254.0 16.4 3e-75 253.8 16.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL45117.1 - 4.7e-28 98.1 45.6 5.3e-23 81.5 18.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Brr6_like_C_C PF10104.9 KXL45117.1 - 1.9 8.2 4.4 1.3 8.8 1.1 2.3 2 0 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain Aa_trans PF01490.18 KXL45119.1 - 1e-37 129.9 23.8 1e-37 129.9 23.8 1.4 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein NmrA PF05368.13 KXL45120.1 - 2.7e-17 63.1 0.0 3.9e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXL45120.1 - 2e-11 44.1 0.0 3.2e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXL45120.1 - 6.2e-06 26.5 0.0 1.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KXL45120.1 - 7e-05 22.4 0.1 0.00013 21.6 0.1 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KXL45120.1 - 0.011 16.1 0.3 0.031 14.7 0.3 1.8 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 KXL45120.1 - 0.016 15.1 0.1 0.028 14.3 0.1 1.5 1 1 0 1 1 1 0 KR domain GDP_Man_Dehyd PF16363.5 KXL45120.1 - 0.029 13.8 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KXL45120.1 - 0.21 11.0 1.3 0.42 10.0 0.6 1.8 1 1 1 2 2 2 0 short chain dehydrogenase Pyridox_ox_2 PF12900.7 KXL45121.1 - 3.1e-31 108.2 0.0 4e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PPR_2 PF13041.6 KXL45122.1 - 0.034 14.4 0.0 9.7 6.5 0.0 3.1 3 0 0 3 3 3 0 PPR repeat family DUF1749 PF08538.10 KXL45122.1 - 0.056 12.5 0.1 0.1 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) COX7a PF02238.15 KXL45123.1 - 3e-24 85.1 1.9 3.8e-24 84.8 1.9 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII Acetyltransf_2 PF00797.17 KXL45124.1 - 1.8e-33 116.3 0.6 1.6e-30 106.6 0.3 2.0 2 0 0 2 2 2 2 N-acetyltransferase Mito_carr PF00153.27 KXL45125.1 - 4e-46 154.9 0.1 3.6e-17 62.1 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Sgf11_N PF18519.1 KXL45125.1 - 0.22 11.1 0.6 0.57 9.8 0.0 1.9 2 0 0 2 2 2 0 SAGA-associated factor 11 N-terminal domain Sugar_tr PF00083.24 KXL45129.1 - 1.8e-28 99.6 28.1 1.7e-19 70.1 12.3 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXL45129.1 - 6.4e-16 58.2 39.7 4e-14 52.3 32.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NapE PF06796.11 KXL45130.1 - 0.038 13.5 2.8 0.056 13.0 2.8 1.3 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE Rep_fac-A_3 PF08661.11 KXL45131.1 - 0.021 15.1 0.0 0.039 14.3 0.0 1.4 1 0 0 1 1 1 0 Replication factor A protein 3 Big_4 PF07532.11 KXL45131.1 - 0.026 14.3 0.3 0.26 11.1 0.1 2.1 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 4) BEX PF04538.12 KXL45132.1 - 0.13 12.9 1.9 0.15 12.7 1.9 1.1 1 0 0 1 1 1 0 Brain expressed X-linked like family DUF4470 PF14737.6 KXL45133.1 - 1.7e-26 92.3 0.3 8.8e-26 90.0 0.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 KXL45133.1 - 8.5e-09 35.4 11.2 1.6e-08 34.5 11.2 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KXL45133.1 - 2.7 8.4 10.2 8 6.9 10.2 1.8 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding MLVIN_C PF18697.1 KXL45134.1 - 0.073 13.2 0.0 0.12 12.5 0.0 1.4 1 1 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain XAP5 PF04921.14 KXL45138.1 - 9e-83 277.9 0.0 1.3e-82 277.4 0.0 1.2 1 0 0 1 1 1 1 XAP5, circadian clock regulator DUF4604 PF15377.6 KXL45138.1 - 0.014 15.8 2.5 0.014 15.8 2.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) TPR_1 PF00515.28 KXL45139.1 - 5.5e-08 32.3 0.1 0.0072 16.1 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXL45139.1 - 2.7e-06 27.0 0.2 0.11 12.6 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXL45139.1 - 5.2e-06 26.7 0.8 1.2e-05 25.5 0.1 2.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXL45139.1 - 6.8e-05 22.5 0.3 0.00017 21.2 0.1 1.8 2 0 0 2 2 2 1 TPR repeat TPR_7 PF13176.6 KXL45139.1 - 0.0022 17.9 0.0 0.42 10.7 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXL45139.1 - 0.0034 17.8 0.0 0.009 16.5 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXL45139.1 - 0.0075 17.0 0.2 2.1 9.4 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXL45139.1 - 0.019 15.2 0.1 0.84 10.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Fungal_trans PF04082.18 KXL45140.1 - 1.8e-18 66.5 0.1 3.7e-18 65.5 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL45140.1 - 6.5e-05 23.0 7.5 0.00015 21.9 7.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Actin PF00022.19 KXL45141.1 - 1.3e-87 294.0 0.0 2.7e-52 177.7 0.0 2.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 KXL45141.1 - 0.0065 15.3 0.0 0.54 9.0 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein Asparaginase_2 PF01112.18 KXL45142.1 - 1.4e-44 152.4 3.1 3.5e-28 98.5 0.0 2.2 2 0 0 2 2 2 2 Asparaginase MFS_1 PF07690.16 KXL45143.1 - 4.2e-28 98.3 82.5 6.9e-24 84.4 49.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KXL45143.1 - 7.1e-05 22.3 33.9 8.8e-05 22.0 33.9 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB CPP1-like PF11833.8 KXL45143.1 - 5.1 6.7 5.1 4.7 6.8 2.6 2.3 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like tRNA_U5-meth_tr PF05958.11 KXL45144.1 - 5.6e-14 51.9 0.0 2.1e-13 50.0 0.0 2.0 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 KXL45144.1 - 7.7e-08 32.1 0.0 1.6e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 KXL45144.1 - 2.5e-06 28.1 0.0 7.4e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL45144.1 - 4.6e-06 26.5 0.0 1.3e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXL45144.1 - 1.3e-05 24.8 0.1 2.4e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KXL45144.1 - 0.00029 21.4 0.0 0.00078 20.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL45144.1 - 0.00036 21.2 0.0 0.001 19.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXL45144.1 - 0.0028 17.2 0.0 0.0049 16.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 KXL45144.1 - 0.022 14.5 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_4 PF02390.17 KXL45144.1 - 0.073 12.5 0.1 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_23 PF13489.6 KXL45144.1 - 0.083 12.7 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KXL45144.1 - 0.11 12.1 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 APG6_N PF17675.1 KXL45144.1 - 0.13 12.8 5.0 1.1 9.8 0.3 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF349 PF03993.12 KXL45144.1 - 0.18 12.1 1.2 1.2 9.5 0.4 2.6 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) adh_short_C2 PF13561.6 KXL45145.1 - 1e-48 165.9 0.2 1.3e-48 165.6 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL45145.1 - 2.3e-39 134.9 0.1 3.1e-39 134.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL45145.1 - 2.4e-09 37.4 0.1 3.1e-09 37.0 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL45145.1 - 8.4e-05 22.1 0.0 0.00018 21.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXL45145.1 - 0.0011 18.9 0.1 0.022 14.6 0.0 2.2 2 0 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXL45145.1 - 0.008 15.3 0.0 0.013 14.6 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KXL45145.1 - 0.018 14.5 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KXL45145.1 - 0.021 13.9 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain DUF3337 PF11816.8 KXL45146.1 - 4.9e-59 199.0 0.0 1.1e-58 197.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 KXL45146.1 - 4.4e-19 68.5 15.5 6.6e-05 23.6 0.2 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.8 KXL45146.1 - 0.012 14.2 1.2 0.042 12.5 1.2 1.9 1 1 0 1 1 1 0 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KXL45146.1 - 0.043 14.1 0.2 3 8.2 0.1 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXL45146.1 - 0.071 12.1 0.0 0.25 10.3 0.0 1.9 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Me-amine-dh_H PF06433.11 KXL45146.1 - 0.08 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) Glycos_transf_1 PF00534.20 KXL45147.1 - 1.4e-31 109.4 0.0 2.2e-30 105.5 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXL45147.1 - 7.8e-17 61.8 0.0 1.6e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KXL45147.1 - 1.3e-15 58.0 0.0 1.4e-14 54.6 0.0 2.4 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KXL45147.1 - 4e-06 27.4 0.0 1.3e-05 25.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_4_5 PF16994.5 KXL45147.1 - 0.0036 16.9 0.0 0.027 14.1 0.0 2.3 2 0 0 2 2 2 1 Glycosyl-transferase family 4 FAM219A PF15260.6 KXL45147.1 - 0.051 13.9 0.0 0.098 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein family FAM219A FixS PF03597.15 KXL45147.1 - 0.4 10.4 3.0 0.79 9.5 3.0 1.4 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Peptidase_C48 PF02902.19 KXL45149.1 - 3.4e-16 59.7 0.0 4e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Myb_Cef PF11831.8 KXL45152.1 - 1.4e-47 162.3 3.4 1.4e-47 162.3 3.4 3.8 5 0 0 5 5 5 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 KXL45152.1 - 1.6e-20 73.0 9.4 2e-11 43.9 1.0 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXL45152.1 - 1.3e-18 66.9 3.7 2.5e-12 46.9 1.2 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 KXL45152.1 - 0.053 13.6 2.0 0.096 12.8 0.1 2.6 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF4185 PF13810.6 KXL45153.1 - 4.4e-06 26.2 0.1 6.9e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) Anp1 PF03452.14 KXL45157.1 - 6.3e-111 370.0 0.0 1e-110 369.3 0.0 1.3 1 0 0 1 1 1 1 Anp1 Glyco_tranf_2_4 PF13704.6 KXL45157.1 - 0.035 14.6 0.1 0.094 13.2 0.1 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 2 Rad54_N PF08658.10 KXL45157.1 - 0.041 14.0 0.5 0.077 13.2 0.5 1.4 1 0 0 1 1 1 0 Rad54 N terminal Phage_holin_3_2 PF04550.12 KXL45157.1 - 0.09 13.3 0.4 0.16 12.5 0.4 1.3 1 0 0 1 1 1 0 Phage holin family 2 IBR PF01485.21 KXL45158.1 - 1.6e-15 57.1 28.0 1.5e-09 37.9 3.2 3.9 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain PRK PF00485.18 KXL45160.1 - 1.1e-55 188.5 0.0 1.5e-55 188.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 KXL45160.1 - 7.8e-37 126.7 0.0 1.1e-36 126.2 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase CPT PF07931.12 KXL45160.1 - 5.7e-05 23.0 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 KXL45160.1 - 0.012 15.8 0.0 0.051 13.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KXL45160.1 - 0.012 16.1 0.0 0.024 15.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KXL45160.1 - 0.028 14.4 0.0 0.33 10.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 KXL45160.1 - 0.034 13.4 0.0 0.068 12.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.29 KXL45160.1 - 0.034 14.6 0.0 1.6 9.2 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 KXL45160.1 - 0.078 13.0 0.1 0.19 11.8 0.1 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.27 KXL45160.1 - 0.099 13.2 1.3 0.26 11.8 0.3 2.0 2 0 0 2 2 2 0 ABC transporter AAA_26 PF13500.6 KXL45160.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXL45160.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KXL45160.1 - 0.15 12.5 0.1 1.4 9.4 0.2 2.5 2 1 0 2 2 2 0 AAA domain MobB PF03205.14 KXL45160.1 - 0.16 11.8 0.3 0.63 9.9 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B CLTH PF10607.9 KXL45161.1 - 9.8e-30 103.4 0.1 1.3e-29 103.0 0.1 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KXL45161.1 - 7.7e-08 32.0 0.0 1.6e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 LisH PAT1 PF09770.9 KXL45162.1 - 0 1022.0 2.6 0 1021.4 2.6 1.3 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF262 PF03235.14 KXL45162.1 - 0.095 12.9 0.3 0.19 11.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF262 YlqD PF11068.8 KXL45162.1 - 1.4 9.3 3.7 2.2 8.7 1.4 2.5 2 0 0 2 2 2 0 YlqD protein Glyco_transf_15 PF01793.16 KXL45163.1 - 1.9e-132 441.4 8.5 2.3e-132 441.2 8.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase EGF_3 PF12947.7 KXL45163.1 - 0.16 12.2 2.0 0.31 11.3 2.0 1.4 1 0 0 1 1 1 0 EGF domain Pkinase PF00069.25 KXL45164.1 - 3.7e-20 72.4 0.0 6.4e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 KXL45164.1 - 1e-13 51.5 9.4 3.3e-07 30.9 0.1 5.9 5 0 0 5 5 5 3 WD domain, G-beta repeat HEAT PF02985.22 KXL45164.1 - 8.9e-10 38.0 3.6 0.015 15.5 0.0 5.5 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 KXL45164.1 - 3.8e-05 24.0 0.3 0.35 11.3 0.0 4.4 3 1 1 4 4 4 1 HEAT repeats Pkinase_Tyr PF07714.17 KXL45164.1 - 5.7e-05 22.5 0.0 8.7e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXL45164.1 - 0.00021 20.7 0.0 0.00039 19.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like HEAT_EZ PF13513.6 KXL45164.1 - 0.02 15.4 0.3 5.6 7.6 0.0 3.2 3 0 0 3 3 3 0 HEAT-like repeat Ge1_WD40 PF16529.5 KXL45164.1 - 0.022 13.7 0.1 0.046 12.7 0.1 1.5 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein adh_short_C2 PF13561.6 KXL45165.1 - 8e-54 182.7 0.3 9.7e-54 182.4 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL45165.1 - 2.8e-44 150.9 0.5 3.9e-44 150.5 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL45165.1 - 2.1e-07 31.0 0.3 5.5e-07 29.7 0.3 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL45165.1 - 0.00066 19.2 0.0 0.00078 19.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pneumo_M2 PF07380.11 KXL45165.1 - 0.1 12.9 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Pneumovirus M2 protein BNIP3 PF06553.12 KXL45166.1 - 0.018 14.7 0.5 0.023 14.3 0.5 1.2 1 0 0 1 1 1 0 BNIP3 Ferritin_2 PF13668.6 KXL45167.1 - 7.1e-06 26.3 0.0 1.3e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Ferritin-like domain Amino_oxidase PF01593.24 KXL45168.1 - 3e-62 211.4 0.0 4.5e-62 210.8 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXL45168.1 - 1e-14 54.5 0.1 2e-14 53.5 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXL45168.1 - 3e-08 33.6 1.2 8.2e-08 32.2 1.2 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXL45168.1 - 6.3e-07 28.8 2.1 1.3e-06 27.8 2.1 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KXL45168.1 - 8.2e-07 29.5 1.2 0.00023 21.7 0.9 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXL45168.1 - 9.7e-07 28.3 0.0 1.1e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXL45168.1 - 4.6e-06 25.6 0.5 0.00016 20.5 0.8 2.4 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KXL45168.1 - 2.7e-05 23.7 0.7 5.2e-05 22.8 0.7 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXL45168.1 - 8.6e-05 21.9 1.1 0.00014 21.2 1.1 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KXL45168.1 - 0.0005 19.4 0.2 0.0012 18.1 0.2 1.6 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 KXL45168.1 - 0.00087 18.7 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KXL45168.1 - 0.002 17.3 1.4 0.0032 16.6 0.7 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 KXL45168.1 - 0.0026 16.7 0.0 0.0041 16.0 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 KXL45168.1 - 0.004 16.4 0.3 0.017 14.4 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXL45168.1 - 0.0092 15.2 0.0 0.91 8.6 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXL45168.1 - 0.012 15.7 0.3 1.4 8.9 0.3 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KXL45168.1 - 0.02 13.9 0.3 0.096 11.7 0.5 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 KXL45168.1 - 0.032 13.6 0.2 0.075 12.4 0.2 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KXL45168.1 - 0.05 13.2 0.3 0.1 12.2 0.3 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 KXL45168.1 - 0.082 12.8 1.0 0.17 11.8 1.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KXL45168.1 - 0.18 11.9 0.1 0.45 10.6 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.16 KXL45169.1 - 3.6e-38 131.4 22.8 3.6e-38 131.4 22.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL45169.1 - 1.7e-08 33.8 23.7 4.4e-08 32.4 5.5 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter YiaAB PF05360.14 KXL45169.1 - 1.7 8.9 11.3 7.1 7.0 0.2 3.7 3 0 0 3 3 3 0 yiaA/B two helix domain TFIID_30kDa PF03540.13 KXL45170.1 - 3.5e-24 84.5 0.2 5.4e-24 83.9 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Mre11_DNA_bind PF04152.14 KXL45171.1 - 8.7e-53 179.1 4.4 1.3e-52 178.5 0.9 2.3 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 KXL45171.1 - 3.4e-15 57.1 1.8 3.4e-15 57.1 1.8 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXL45171.1 - 8.4e-06 26.1 0.4 9.5e-05 22.6 0.4 2.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Fructosamin_kin PF03881.14 KXL45171.1 - 0.094 11.9 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Fructosamine kinase Ribosomal_S19 PF00203.21 KXL45172.1 - 3.5e-28 97.3 0.0 4.2e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 IPK PF03770.16 KXL45174.1 - 1.7e-56 191.2 0.0 3.8e-56 190.1 0.0 1.7 1 0 0 1 1 1 1 Inositol polyphosphate kinase Aa_trans PF01490.18 KXL45176.1 - 5.7e-31 107.6 24.5 8.1e-31 107.1 24.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Phage_T4_gp36 PF03903.13 KXL45177.1 - 0.11 12.5 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Phage T4 tail fibre UNC45-central PF11701.8 KXL45178.1 - 6.5e-42 143.1 1.8 6.5e-42 143.1 1.8 4.1 5 0 0 5 5 5 1 Myosin-binding striated muscle assembly central Arm PF00514.23 KXL45178.1 - 0.00016 21.6 14.2 3.1 8.0 0.0 7.8 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat TAF6_C PF07571.13 KXL45178.1 - 0.073 13.4 2.9 3.2 8.1 0.0 3.9 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain TM_PBP2_N PF16296.5 KXL45178.1 - 0.11 12.6 0.0 0.53 10.5 0.0 2.2 1 0 0 1 1 1 0 N-terminal of TM subunit in PBP-dependent ABC transporters HrpB1_HrpK PF09613.10 KXL45178.1 - 0.2 11.3 7.2 0.055 13.1 0.6 3.2 3 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) HEAT_2 PF13646.6 KXL45178.1 - 0.45 10.9 16.5 3.4 8.1 1.0 5.6 3 2 2 5 5 5 0 HEAT repeats Alkyl_sulf_dimr PF14863.6 KXL45178.1 - 9.3 6.7 7.7 75 3.8 0.0 4.4 4 1 1 5 5 5 0 Alkyl sulfatase dimerisation PQ-loop PF04193.14 KXL45179.1 - 1.3e-17 63.3 14.6 3.1e-09 36.4 4.6 3.0 2 0 0 2 2 2 2 PQ loop repeat DUF92 PF01940.16 KXL45179.1 - 0.014 14.8 5.6 0.96 8.8 2.1 3.2 3 1 0 3 3 3 0 Integral membrane protein DUF92 DUF4191 PF13829.6 KXL45179.1 - 1.3 8.3 14.6 0.05 12.9 2.4 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4191) Orf78 PF06024.12 KXL45179.1 - 1.5 9.2 0.0 1.5 9.2 0.0 2.5 4 0 0 4 4 4 0 Orf78 (ac78) MFS_1 PF07690.16 KXL45180.1 - 1.3e-30 106.5 23.9 1.3e-30 106.5 23.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily PTR2 PF00854.21 KXL45180.1 - 3.8e-05 22.7 0.3 0.00017 20.5 0.3 1.9 1 1 0 1 1 1 1 POT family TssN PF17555.2 KXL45180.1 - 7.6 5.8 9.6 0.12 11.8 2.0 1.8 2 0 0 2 2 2 0 Type VI secretion system, TssN NMD3 PF04981.13 KXL45181.1 - 1e-77 260.9 3.1 1.4e-77 260.4 3.1 1.2 1 0 0 1 1 1 1 NMD3 family HypA PF01155.19 KXL45181.1 - 0.025 14.6 4.0 1 9.4 0.2 2.9 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF3797 PF12677.7 KXL45181.1 - 0.1 12.5 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) TackOD1 PF18551.1 KXL45181.1 - 0.21 11.2 2.9 4.5 6.9 0.2 2.4 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 DZR PF12773.7 KXL45181.1 - 0.38 10.8 7.6 43 4.2 7.6 2.8 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 KXL45181.1 - 0.76 9.3 2.6 9.9 5.7 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 KXL45181.1 - 2.6 8.1 6.4 3.4 7.7 0.6 2.8 2 1 1 3 3 3 0 zinc-ribbons HscB_4_cys PF18256.1 KXL45181.1 - 9.1 6.2 8.4 0.086 12.7 0.6 1.8 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif eIF-5_eIF-2B PF01873.17 KXL45181.1 - 10 6.1 9.0 3.5 7.5 0.1 2.8 3 0 0 3 3 3 0 Domain found in IF2B/IF5 ThiF PF00899.21 KXL45182.1 - 4.5e-67 225.9 0.1 7.6e-67 225.2 0.1 1.4 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 KXL45182.1 - 4.8e-11 43.1 0.4 4.8e-05 23.4 0.0 2.9 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site UAE_UbL PF14732.6 KXL45182.1 - 9e-09 35.8 0.2 2.4e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain SLT PF01464.20 KXL45183.1 - 0.0013 18.3 0.3 0.0051 16.4 0.2 2.2 2 1 0 2 2 2 1 Transglycosylase SLT domain Lysozyme_like PF13702.6 KXL45183.1 - 0.0057 16.4 1.4 0.0084 15.8 1.4 1.4 1 1 0 1 1 1 1 Lysozyme-like Fimbrial_K88 PF02432.15 KXL45183.1 - 0.031 14.2 1.1 0.61 10.0 0.2 2.2 1 1 1 2 2 2 0 Fimbrial, major and minor subunit SLT_2 PF13406.6 KXL45183.1 - 0.1 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Transglycosylase SLT domain DUF3290 PF11694.8 KXL45183.1 - 0.18 11.8 0.0 0.26 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) Q_salvage PF10343.9 KXL45185.1 - 5.5e-118 393.6 0.0 6.6e-118 393.4 0.0 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family Rad60-SLD_2 PF13881.6 KXL45186.1 - 2.4e-10 40.5 0.0 4.3e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Pex14_N PF04695.13 KXL45186.1 - 1.6 9.4 10.0 2.3 8.9 10.0 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region UMP1 PF05348.11 KXL45187.1 - 4.1e-35 120.6 0.0 5e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Hol_Tox PF16935.5 KXL45188.1 - 0.095 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Putative Holin-like Toxin (Hol-Tox) Zn_Tnp_IS1595 PF12760.7 KXL45188.1 - 0.13 12.2 0.2 0.27 11.2 0.2 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Rad60-SLD PF11976.8 KXL45189.1 - 0.018 14.8 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like USP7_ICP0_bdg PF12436.8 KXL45189.1 - 0.034 13.5 0.2 0.52 9.6 0.0 2.0 1 1 1 2 2 2 0 ICP0-binding domain of Ubiquitin-specific protease 7 ubiquitin PF00240.23 KXL45189.1 - 0.15 11.9 0.0 0.27 11.0 0.0 1.5 2 0 0 2 2 2 0 Ubiquitin family WD40 PF00400.32 KXL45190.1 - 1.5e-06 28.8 8.3 0.098 13.6 0.0 5.1 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL45190.1 - 0.00053 20.2 0.0 0.081 13.2 0.0 3.1 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Cpn10 PF00166.21 KXL45191.1 - 8.9e-30 102.6 0.0 1e-29 102.4 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit RRM_1 PF00076.22 KXL45192.1 - 8.1e-29 99.3 0.7 1.9e-14 53.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXL45192.1 - 3.3e-08 33.2 0.0 0.0012 18.5 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXL45192.1 - 0.0058 16.5 0.0 0.2 11.5 0.0 2.2 2 0 0 2 2 2 1 Occluded RNA-recognition motif MFS_1 PF07690.16 KXL45193.1 - 5.5e-43 147.2 18.6 4e-40 137.8 12.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXL45193.1 - 0.0004 19.1 16.3 0.0048 15.5 0.2 3.3 3 1 1 4 4 4 2 MFS/sugar transport protein OATP PF03137.20 KXL45193.1 - 0.044 12.1 2.8 0.47 8.7 0.9 2.4 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family IL1_propep PF02394.16 KXL45194.1 - 0.15 13.0 0.0 0.17 12.8 0.0 1.1 1 0 0 1 1 1 0 Interleukin-1 propeptide DUF2530 PF10745.9 KXL45195.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) GARP PF16731.5 KXL45196.1 - 0.11 12.1 3.2 0.058 13.1 1.0 1.6 2 0 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma Gram_pos_anchor PF00746.21 KXL45197.1 - 0.077 12.9 0.7 0.17 11.8 0.7 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif SKG6 PF08693.10 KXL45197.1 - 3.7 7.0 5.5 1.1 8.8 1.1 2.3 2 0 0 2 2 2 0 Transmembrane alpha-helix domain HSP70 PF00012.20 KXL45198.1 - 0.005 15.1 0.1 0.016 13.4 0.1 1.7 1 1 0 1 1 1 1 Hsp70 protein DDR PF08841.10 KXL45198.1 - 0.0074 15.3 0.8 0.11 11.5 1.4 2.4 2 1 1 3 3 3 1 Diol dehydratase reactivase ATPase-like domain MreB_Mbl PF06723.13 KXL45198.1 - 0.084 11.7 0.4 0.91 8.3 0.5 2.0 2 0 0 2 2 2 0 MreB/Mbl protein OB_NTP_bind PF07717.16 KXL45200.1 - 1.5e-24 86.2 0.0 4.1e-24 84.8 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KXL45200.1 - 2.1e-18 66.5 0.1 5.3e-18 65.3 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KXL45200.1 - 2.7e-11 43.8 0.0 7.3e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXL45200.1 - 1.9e-08 34.3 0.5 3.9e-08 33.3 0.5 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KXL45200.1 - 1.8e-05 25.0 0.1 6e-05 23.3 0.1 1.9 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KXL45200.1 - 0.0012 18.5 0.4 0.0039 16.8 0.4 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 KXL45200.1 - 0.0024 17.9 0.1 0.0057 16.6 0.1 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_19 PF13245.6 KXL45200.1 - 0.0047 17.3 0.3 0.01 16.2 0.3 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXL45200.1 - 0.0075 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KXL45200.1 - 0.066 13.7 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KXL45200.1 - 0.074 12.1 0.0 0.27 10.2 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein Glyco_transf_17 PF04724.13 KXL45201.1 - 8.2e-54 182.9 2.7 9.7e-52 176.1 2.7 2.7 1 1 0 1 1 1 1 Glycosyltransferase family 17 Methyltransf_33 PF10017.9 KXL45202.1 - 3.9e-89 298.8 0.3 5.2e-89 298.4 0.3 1.1 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 KXL45202.1 - 2.9e-17 63.1 0.7 9.8e-09 35.2 0.2 2.3 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KXL45202.1 - 0.0099 16.4 1.4 0.35 11.4 1.4 2.7 1 1 0 1 1 1 1 DinB superfamily CS PF04969.16 KXL45203.1 - 5e-05 24.2 0.3 9.9e-05 23.3 0.3 1.5 1 1 0 1 1 1 1 CS domain Snf7 PF03357.21 KXL45204.1 - 4.8e-22 78.4 9.5 7.5e-22 77.7 9.5 1.2 1 0 0 1 1 1 1 Snf7 AA_permease_2 PF13520.6 KXL45205.1 - 1.7e-49 168.8 47.7 2.2e-49 168.4 47.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXL45205.1 - 4.2e-19 68.5 39.3 6.5e-19 67.9 39.3 1.2 1 0 0 1 1 1 1 Amino acid permease Thr_synth_N PF14821.6 KXL45206.1 - 1.6e-28 98.7 0.0 4e-28 97.4 0.0 1.8 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 KXL45206.1 - 6.9e-18 65.1 0.0 3.8e-17 62.6 0.0 1.9 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme BLUF PF04940.12 KXL45206.1 - 0.011 15.8 0.0 0.036 14.2 0.0 1.8 2 0 0 2 2 2 0 Sensors of blue-light using FAD FAD_binding_4 PF01565.23 KXL45207.1 - 9.9e-20 70.7 5.7 9.9e-20 70.7 5.7 2.1 3 0 0 3 3 3 1 FAD binding domain BBE PF08031.12 KXL45207.1 - 0.018 15.2 0.1 0.037 14.1 0.1 1.5 1 0 0 1 1 1 0 Berberine and berberine like HAD_2 PF13419.6 KXL45208.1 - 6.5e-21 75.2 0.0 1e-20 74.6 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXL45208.1 - 1.8e-08 34.9 0.0 2.3e-06 28.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NT5C PF06941.12 KXL45208.1 - 0.0037 17.2 0.0 0.015 15.2 0.0 1.9 1 1 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Hydrolase_like PF13242.6 KXL45208.1 - 0.0074 16.3 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.18 KXL45208.1 - 0.1 12.4 0.0 0.2 11.4 0.0 1.5 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase DUF3435 PF11917.8 KXL45212.1 - 6.7e-151 502.9 0.5 9.4e-151 502.5 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Phage_integrase PF00589.22 KXL45212.1 - 0.008 16.0 0.1 0.046 13.5 0.0 2.2 2 0 0 2 2 2 1 Phage integrase family E1-E2_ATPase PF00122.20 KXL45213.1 - 1.2e-46 158.5 2.4 2.8e-46 157.3 2.4 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KXL45213.1 - 2e-23 83.8 0.0 3.5e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KXL45213.1 - 1.6e-06 28.4 0.1 5.7e-06 26.7 0.1 2.0 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KXL45213.1 - 6.3e-05 22.8 0.1 0.0055 16.5 0.1 2.7 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase MauE PF07291.11 KXL45213.1 - 0.073 12.8 3.4 0.067 13.0 1.2 2.0 2 0 0 2 2 2 0 Methylamine utilisation protein MauE Na_Ca_ex PF01699.24 KXL45214.1 - 2.8e-15 56.6 10.5 3.5e-15 56.3 10.5 1.1 1 0 0 1 1 1 1 Sodium/calcium exchanger protein Yip1 PF04893.17 KXL45214.1 - 1.3 8.7 10.0 1.9 8.2 10.0 1.3 1 0 0 1 1 1 0 Yip1 domain GCIP PF13324.6 KXL45215.1 - 0.034 13.7 0.6 0.035 13.7 0.6 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting FAM176 PF14851.6 KXL45215.1 - 0.12 12.0 0.8 0.18 11.4 0.8 1.3 1 0 0 1 1 1 0 FAM176 family K_trans PF02705.16 KXL45216.1 - 4.9e-176 586.4 16.7 5.8e-176 586.1 16.7 1.0 1 0 0 1 1 1 1 K+ potassium transporter zf-RING_2 PF13639.6 KXL45217.1 - 1.3e-12 47.8 2.0 2e-12 47.2 2.0 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXL45217.1 - 4.8e-11 42.3 2.2 7.2e-11 41.7 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXL45217.1 - 2.1e-08 33.9 1.0 3.3e-08 33.3 1.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXL45217.1 - 2.5e-08 33.5 0.9 2.5e-08 33.5 0.9 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 KXL45217.1 - 6e-08 32.9 4.4 8.9e-08 32.3 4.4 1.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KXL45217.1 - 1.4e-05 24.9 3.6 1.8e-05 24.6 3.6 1.2 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KXL45217.1 - 3.2e-05 23.7 2.4 5.2e-05 23.0 2.4 1.4 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KXL45217.1 - 7.1e-05 22.3 3.8 8.8e-05 22.1 3.8 1.3 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 KXL45217.1 - 9e-05 22.5 1.1 9.8e-05 22.3 1.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KXL45217.1 - 0.00023 21.1 1.3 0.00032 20.6 0.4 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXL45217.1 - 0.0015 18.3 1.6 0.0022 17.8 1.6 1.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KXL45217.1 - 0.0082 15.9 1.6 0.015 15.1 1.5 1.5 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain Zf_RING PF16744.5 KXL45217.1 - 0.028 14.5 1.1 0.032 14.3 0.5 1.4 1 1 0 1 1 1 0 KIAA1045 RING finger RINGv PF12906.7 KXL45217.1 - 0.04 14.0 3.1 0.096 12.8 3.1 1.7 1 1 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 KXL45217.1 - 0.11 12.9 4.8 0.23 11.8 4.8 1.7 1 1 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.6 KXL45217.1 - 0.24 11.6 3.9 0.85 9.8 3.9 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KXL45217.1 - 1.2 9.4 6.2 0.39 10.9 1.5 2.3 1 1 1 2 2 2 0 FANCL C-terminal domain AhpC-TSA PF00578.21 KXL45218.1 - 2.7e-30 104.8 0.0 3.6e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXL45218.1 - 4.5e-12 45.9 0.0 6e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KXL45218.1 - 6.8e-08 32.2 0.0 1.3e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin GED PF02212.18 KXL45220.1 - 1.2e-05 25.4 0.0 0.00014 22.0 0.0 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain DUF1128 PF06569.11 KXL45220.1 - 0.035 14.1 0.0 0.19 11.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) RNA_pol_Rbc25 PF08292.12 KXL45220.1 - 0.041 14.1 0.1 0.1 12.8 0.1 1.7 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 HET PF06985.11 KXL45221.1 - 6.3e-23 81.8 0.1 8.9e-23 81.3 0.1 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RecR PF02132.15 KXL45221.1 - 0.016 14.7 0.4 1.9 8.1 0.0 2.7 2 0 0 2 2 2 0 RecR protein 2OG-FeII_Oxy PF03171.20 KXL45222.1 - 2e-18 66.7 0.0 3.7e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KXL45222.1 - 3.2e-14 53.7 0.0 4.4e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal ADH_N PF08240.12 KXL45223.1 - 2.8e-23 81.9 0.4 3.3e-23 81.6 0.4 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glyco_hydro_47 PF01532.20 KXL45224.1 - 5.1e-55 187.2 0.0 6.1e-55 186.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 ATP-synt_C PF00137.21 KXL45225.1 - 4.6e-10 39.7 11.9 4.6e-10 39.7 11.9 1.7 2 0 0 2 2 2 1 ATP synthase subunit C Aldo_ket_red PF00248.21 KXL45226.1 - 3.8e-61 206.8 0.0 4.3e-61 206.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HET PF06985.11 KXL45227.1 - 3.2e-37 128.1 0.9 3.7e-37 127.9 0.9 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ribosomal_S7 PF00177.21 KXL45228.1 - 5.5e-28 97.5 0.0 8.8e-28 96.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e ENTH PF01417.20 KXL45229.1 - 1.4e-45 154.4 0.0 2.2e-45 153.7 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KXL45229.1 - 0.00062 18.9 0.0 0.00092 18.3 0.0 1.2 1 0 0 1 1 1 1 ANTH domain DUF1720 PF08226.11 KXL45229.1 - 0.0028 18.0 37.9 0.0028 18.0 37.9 4.7 1 1 2 3 3 3 1 Domain of unknown function (DUF1720) UIM PF02809.20 KXL45229.1 - 0.0058 16.5 1.2 0.0058 16.5 1.2 2.8 2 0 0 2 2 2 1 Ubiquitin interaction motif VHS PF00790.19 KXL45229.1 - 0.01 15.7 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 0 VHS domain Methyltransf_16 PF10294.9 KXL45230.1 - 8.9e-19 67.9 0.0 2.1e-14 53.6 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 KXL45230.1 - 0.0013 18.6 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXL45230.1 - 0.079 12.3 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Glyco_hydro_47 PF01532.20 KXL45232.1 - 2.8e-67 227.6 0.1 3.2e-67 227.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DnaJ PF00226.31 KXL45234.1 - 1.6e-21 76.2 2.7 1.6e-21 76.2 2.7 2.0 2 0 0 2 2 2 1 DnaJ domain DUF4878 PF12870.7 KXL45234.1 - 0.11 12.8 3.8 0.07 13.4 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4878) Rav1p_C PF12234.8 KXL45235.1 - 1.7e-86 291.1 4.0 1.9e-86 290.9 4.0 1.0 1 0 0 1 1 1 1 RAVE protein 1 C terminal DUF1168 PF06658.12 KXL45236.1 - 3.1e-41 140.4 13.6 5e-41 139.7 13.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Lyase_catalyt PF09093.11 KXL45236.1 - 0.021 13.9 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 Lyase, catalytic Membralin PF09746.9 KXL45236.1 - 0.74 8.8 1.4 0.91 8.5 1.4 1.0 1 0 0 1 1 1 0 Tumour-associated protein TMEM214 PF10151.9 KXL45236.1 - 3.4 6.0 4.2 4.4 5.6 4.2 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Presenilin PF01080.17 KXL45236.1 - 4.3 6.0 3.8 3.9 6.1 3.8 1.1 1 0 0 1 1 1 0 Presenilin His_Phos_1 PF00300.22 KXL45237.1 - 4.1e-21 75.6 1.2 5.6e-20 71.9 1.2 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 KXL45237.1 - 0.00047 19.6 0.3 0.0013 18.2 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) SUR7 PF06687.12 KXL45238.1 - 1e-09 38.4 4.0 1e-09 38.4 4.0 1.6 1 1 1 2 2 2 1 SUR7/PalI family MRAP PF15183.6 KXL45238.1 - 0.036 14.0 1.1 0.036 14.0 1.1 1.9 1 1 1 2 2 2 0 Melanocortin-2 receptor accessory protein family EphA2_TM PF14575.6 KXL45238.1 - 0.12 13.3 0.8 1.1 10.2 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Rhabdo_glycop PF00974.18 KXL45238.1 - 0.19 10.2 0.1 0.23 9.8 0.1 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein RCR PF12273.8 KXL45238.1 - 0.28 11.8 1.2 0.58 10.8 0.1 1.9 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red HemY_N PF07219.13 KXL45238.1 - 1.6 9.0 3.6 10 6.4 0.1 2.3 2 0 0 2 2 2 0 HemY protein N-terminus DHHC PF01529.20 KXL45238.1 - 2 8.5 9.0 3 8.0 8.3 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase DUF4079 PF13301.6 KXL45238.1 - 2 8.5 9.2 1.3 9.2 3.3 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF4079) DUF4389 PF14333.6 KXL45238.1 - 7.7 6.5 12.5 13 5.8 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) DUF3040 PF11239.8 KXL45238.1 - 9.2 6.6 10.7 6.9 7.0 2.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) Yip1 PF04893.17 KXL45239.1 - 0.016 14.9 3.2 0.016 14.9 3.2 1.8 2 0 0 2 2 2 0 Yip1 domain p450 PF00067.22 KXL45240.1 - 1.6e-57 195.3 0.0 2.2e-57 194.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 KXL45241.1 - 1.3e-35 123.1 3.9 1.6e-35 122.8 3.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL45241.1 - 1e-25 90.4 6.9 1.6e-25 89.7 6.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL45241.1 - 9e-09 35.5 2.6 1.3e-08 34.9 2.6 1.2 1 0 0 1 1 1 1 KR domain CDC45 PF02724.14 KXL45243.1 - 1e-59 202.5 0.0 1.2e-59 202.2 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 KXL45243.1 - 1.2 7.3 6.5 1.4 7.0 6.5 1.0 1 0 0 1 1 1 0 Nop14-like family Abhydrolase_4 PF08386.10 KXL45245.1 - 1.4e-20 73.3 0.0 3.6e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KXL45245.1 - 3.4e-16 59.7 0.0 1.1e-13 51.4 0.0 2.8 2 1 0 2 2 2 2 alpha/beta hydrolase fold BRAP2 PF07576.12 KXL45246.1 - 2.6e-30 104.5 0.0 4.8e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 KXL45246.1 - 3.3e-19 69.0 7.1 8.1e-19 67.7 7.1 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 KXL45246.1 - 2.6e-08 34.0 8.8 2.6e-08 34.0 8.8 2.2 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXL45246.1 - 2.2e-06 27.4 8.2 5.8e-06 26.0 8.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXL45246.1 - 1.9e-05 24.4 7.3 5.7e-05 22.9 7.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXL45246.1 - 0.00012 22.0 5.0 0.00064 19.7 5.0 2.2 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KXL45246.1 - 0.00015 22.0 6.0 0.00049 20.3 6.0 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KXL45246.1 - 0.00034 20.3 4.9 0.00034 20.3 4.9 2.2 2 0 0 2 2 2 1 RING-like zinc finger GARP PF16731.5 KXL45246.1 - 0.0013 18.4 17.0 0.0013 18.4 17.0 1.8 2 0 0 2 2 2 1 Glutamic acid/alanine-rich protein of Trypanosoma zf-RING_6 PF14835.6 KXL45246.1 - 0.0016 18.3 3.4 0.0084 16.0 3.4 2.2 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.6 KXL45246.1 - 0.0016 18.3 6.8 0.0016 18.3 6.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXL45246.1 - 0.0024 17.8 6.5 0.0024 17.8 6.5 2.1 2 0 0 2 2 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KXL45246.1 - 0.027 14.5 5.6 0.074 13.1 5.6 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger ATG16 PF08614.11 KXL45246.1 - 0.042 14.1 12.6 0.08 13.2 12.6 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) HTH_Tnp_1 PF01527.20 KXL45246.1 - 0.049 14.0 5.7 0.11 12.8 5.7 1.5 1 0 0 1 1 1 0 Transposase CENP-Q PF13094.6 KXL45246.1 - 0.061 13.5 11.9 0.11 12.7 11.9 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Phlebovirus_NSM PF07246.11 KXL45246.1 - 0.11 11.8 1.4 0.18 11.2 1.4 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF1993 PF09351.10 KXL45246.1 - 0.15 12.2 3.3 0.32 11.1 3.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) DUF3391 PF11871.8 KXL45246.1 - 0.95 10.0 8.2 2.5 8.6 8.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DUF4407 PF14362.6 KXL45246.1 - 0.99 8.7 8.7 1.6 8.1 8.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-RING_4 PF14570.6 KXL45246.1 - 1.8 8.4 5.5 4.9 7.0 5.5 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KXL45246.1 - 2.8 7.9 19.4 0.29 11.0 9.3 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Exonuc_VII_L PF02601.15 KXL45246.1 - 5.7 6.4 9.2 8 5.9 9.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMPIT PF07851.13 KXL45246.1 - 6.3 5.9 5.3 9.9 5.3 5.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein CSN5_C PF18323.1 KXL45246.1 - 7.9 7.5 7.0 44 5.1 6.7 2.3 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain CLASP_N PF12348.8 KXL45248.1 - 1e-06 28.5 0.4 2.3e-05 24.1 0.2 2.3 2 0 0 2 2 2 1 CLASP N terminal Fez1 PF06818.15 KXL45248.1 - 0.00026 21.5 1.6 0.00026 21.5 1.6 2.1 3 0 0 3 3 2 1 Fez1 ATG16 PF08614.11 KXL45248.1 - 0.0018 18.5 7.2 0.0018 18.5 7.2 2.6 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Syntaxin PF00804.25 KXL45248.1 - 0.031 13.9 8.8 0.015 15.0 4.2 2.4 2 0 0 2 2 2 0 Syntaxin HEAT PF02985.22 KXL45248.1 - 0.036 14.3 0.3 26 5.4 0.1 4.2 4 0 0 4 4 4 0 HEAT repeat BRE1 PF08647.11 KXL45248.1 - 0.16 12.0 10.6 2.4 8.3 6.5 3.1 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase End3 PF12761.7 KXL45248.1 - 0.2 11.8 6.5 0.41 10.8 6.5 1.5 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Leu_zip PF15294.6 KXL45248.1 - 0.24 10.9 11.1 0.02 14.5 5.8 1.7 2 0 0 2 2 2 0 Leucine zipper Spc7 PF08317.11 KXL45248.1 - 0.26 10.1 11.9 0.013 14.4 4.3 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein bZIP_2 PF07716.15 KXL45248.1 - 0.36 10.9 15.0 0.53 10.4 1.9 4.0 2 1 1 3 3 3 0 Basic region leucine zipper HALZ PF02183.18 KXL45248.1 - 0.8 10.0 8.8 1.3 9.3 3.1 2.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper Bap31_Bap29_C PF18035.1 KXL45248.1 - 0.85 9.7 5.0 1 9.4 1.9 2.6 1 1 1 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Snapin_Pallidin PF14712.6 KXL45248.1 - 1.4 9.4 10.2 6.8 7.2 10.2 2.3 1 0 0 1 1 1 0 Snapin/Pallidin DivIC PF04977.15 KXL45248.1 - 1.6 8.6 13.8 1.8 8.4 5.0 2.9 1 1 1 2 2 2 0 Septum formation initiator Spc24 PF08286.11 KXL45248.1 - 1.6 9.0 11.3 8.4 6.7 1.3 2.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF4200 PF13863.6 KXL45248.1 - 2 8.8 10.9 11 6.4 10.9 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Atg14 PF10186.9 KXL45248.1 - 2.1 7.4 11.1 4.8 6.2 11.1 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 V_ATPase_I PF01496.19 KXL45248.1 - 3.1 5.6 3.7 1.2 7.0 1.1 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family ZapB PF06005.12 KXL45248.1 - 3.1 8.3 18.5 0.08 13.4 2.1 4.1 5 0 0 5 5 3 0 Cell division protein ZapB DUF5082 PF16888.5 KXL45248.1 - 3.4 8.0 9.2 10 6.4 2.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Golgin_A5 PF09787.9 KXL45248.1 - 3.5 7.0 15.4 0.37 10.2 9.8 2.0 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF4407 PF14362.6 KXL45248.1 - 3.6 6.8 15.3 0.081 12.3 4.4 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) DUF4559 PF15112.6 KXL45248.1 - 3.7 7.1 8.0 2.8 7.5 4.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) DUF724 PF05266.14 KXL45248.1 - 4.7 7.0 10.0 2.6 7.8 7.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) TMF_DNA_bd PF12329.8 KXL45248.1 - 5.5 7.1 12.4 10 6.2 3.9 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding APG6_N PF17675.1 KXL45248.1 - 7.2 7.1 19.9 1.2 9.6 12.1 3.2 2 1 1 3 3 3 0 Apg6 coiled-coil region zf-C4H2 PF10146.9 KXL45248.1 - 7.4 6.8 9.5 11 6.2 5.4 2.7 2 1 0 2 2 2 0 Zinc finger-containing protein WD40 PF00400.32 KXL45249.1 - 3.8e-50 166.8 19.6 1.9e-10 41.1 1.7 8.7 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL45249.1 - 1.3e-12 47.8 0.0 0.00019 21.6 0.0 5.0 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXL45249.1 - 4.2e-05 22.4 0.0 0.0057 15.4 0.0 3.0 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KXL45249.1 - 0.00022 20.1 0.0 1.9 7.1 0.0 3.4 3 1 1 4 4 4 2 Nup133 N terminal like ubiquitin PF00240.23 KXL45251.1 - 3.3e-132 430.4 19.8 3.2e-33 113.3 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 KXL45251.1 - 2.2e-61 203.6 19.7 1.9e-15 56.4 0.7 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KXL45251.1 - 6.6e-23 81.0 10.1 0.00042 20.7 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 KXL45251.1 - 1.8e-16 59.8 3.0 0.026 14.4 0.0 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 KXL45251.1 - 2.8e-15 56.4 7.7 0.027 14.8 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KXL45251.1 - 1.9e-14 53.7 2.7 0.12 12.5 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KXL45251.1 - 4.5e-13 49.7 1.2 0.37 11.4 0.0 4.2 1 1 1 4 4 4 4 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 KXL45251.1 - 1e-09 38.4 0.5 0.5 10.2 0.0 4.1 1 1 3 4 4 4 3 Silencing defective 2 N-terminal ubiquitin domain Methyltrans_RNA PF04452.14 KXL45251.1 - 2.8e-06 26.9 0.4 1.8 7.8 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase DUF3861 PF12977.7 KXL45251.1 - 3.3e-06 27.2 2.3 13 6.1 0.0 4.2 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) Ubiquitin_4 PF18036.1 KXL45251.1 - 5.5e-06 26.3 23.3 16 5.6 0.2 7.8 8 0 0 8 8 8 0 Ubiquitin-like domain DUF2870 PF11069.8 KXL45251.1 - 6.6e-06 26.4 0.0 29 5.1 0.0 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) ACT_5 PF13710.6 KXL45251.1 - 1.1e-05 25.2 4.1 10 6.1 0.0 4.3 4 0 0 4 4 4 0 ACT domain Big_7 PF17957.1 KXL45251.1 - 2.3e-05 25.1 0.6 22 5.9 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig domain UDP-g_GGTase PF06427.11 KXL45251.1 - 6.1e-05 23.1 1.9 7 6.8 0.0 3.5 3 0 0 3 3 3 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 KXL45251.1 - 0.00039 19.9 0.0 23 4.3 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) YcgR_2 PF12945.7 KXL45251.1 - 0.00082 19.5 6.3 23 5.2 0.1 4.3 4 0 0 4 4 4 0 Flagellar protein YcgR DUF493 PF04359.14 KXL45251.1 - 0.003 18.1 0.0 1.4e+02 3.2 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF493) Raf1_HTH PF18579.1 KXL45251.1 - 0.0035 17.0 0.0 1e+02 2.7 0.0 4.1 4 0 0 4 4 4 0 Rubisco accumulation factor 1 helix turn helix domain ACT_4 PF13291.6 KXL45251.1 - 0.0054 17.3 1.0 1.4e+02 3.2 0.0 4.2 4 0 0 4 4 4 0 ACT domain ORF11CD3 PF10549.9 KXL45251.1 - 0.0064 16.6 0.0 90 3.3 0.0 4.3 4 0 0 4 4 4 0 ORF11CD3 domain FLgD_tudor PF13861.6 KXL45251.1 - 0.023 15.0 0.0 6.4 7.1 0.0 3.6 1 1 0 1 1 1 0 FlgD Tudor-like domain ProRS-C_2 PF09181.10 KXL45251.1 - 0.1 12.8 5.8 1e+02 3.1 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal Baculo_p48 PF04878.13 KXL45251.1 - 0.13 11.2 0.0 60 2.4 0.0 2.9 3 0 0 3 3 3 0 Baculovirus P48 protein Tash_PEST PF07708.11 KXL45251.1 - 0.13 12.4 27.2 6.1 7.1 1.4 4.3 4 0 0 4 4 4 0 Tash protein PEST motif HAMP_N3 PF18575.1 KXL45251.1 - 0.22 11.1 1.5 2e+02 1.7 0.0 3.9 4 0 0 4 4 4 0 HAMP N-terminal domain 3 SurA_N PF09312.11 KXL45251.1 - 0.29 11.2 4.1 59 3.8 0.1 3.9 4 0 0 4 4 4 0 SurA N-terminal domain DMA PF03474.14 KXL45251.1 - 0.47 10.1 4.3 1.5e+02 2.1 0.0 4.0 4 0 0 4 4 4 0 DMRTA motif PI3K_p85B PF02192.16 KXL45251.1 - 1.8 8.3 9.3 94 2.8 0.1 4.2 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain Phage_sheath_1N PF17481.2 KXL45251.1 - 2 8.9 10.0 70 4.0 0.3 4.0 1 1 2 3 3 3 0 Phage tail sheath protein beta-sandwich domain Plexin_cytopl PF08337.12 KXL45251.1 - 3.2 6.3 17.1 15 4.1 0.4 4.9 4 3 0 4 4 4 0 Plexin cytoplasmic RasGAP domain ADH_zinc_N PF00107.26 KXL45252.1 - 3.9e-25 88.3 0.0 5.9e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXL45252.1 - 3.4e-17 62.3 2.4 7.1e-17 61.3 2.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXL45252.1 - 3e-06 28.3 0.0 5e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXL45252.1 - 6.5e-06 25.8 0.0 8.2e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus NAD_binding_7 PF13241.6 KXL45252.1 - 0.0019 18.6 0.0 0.0035 17.7 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 KXL45252.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KXL45252.1 - 0.017 15.4 0.1 0.032 14.5 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain XdhC_C PF13478.6 KXL45252.1 - 0.032 14.7 0.1 0.11 13.0 0.0 2.1 2 1 0 2 2 2 0 XdhC Rossmann domain AlaDh_PNT_C PF01262.21 KXL45252.1 - 0.047 13.0 0.0 0.074 12.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KXL45252.1 - 0.12 11.6 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KXL45252.1 - 0.12 13.0 0.6 0.71 10.5 0.2 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXL45253.1 - 3.8e-20 72.4 0.0 8e-20 71.4 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXL45253.1 - 8.4e-07 28.9 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXL45253.1 - 3.9e-06 27.0 0.6 1.2e-05 25.4 0.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXL45253.1 - 1.4e-05 24.4 1.5 0.00017 20.9 1.5 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXL45253.1 - 9.5e-05 21.4 1.2 0.054 12.3 0.9 2.2 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.24 KXL45253.1 - 0.01 14.9 0.7 0.018 14.2 0.7 1.4 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 KXL45253.1 - 0.02 14.2 0.2 0.039 13.2 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KXL45253.1 - 0.087 12.0 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KXL45253.1 - 0.1 11.3 0.4 0.16 10.6 0.4 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 KXL45253.1 - 0.11 13.0 0.3 0.29 11.7 0.3 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXL45253.1 - 0.27 10.2 1.3 3.6 6.5 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein p450 PF00067.22 KXL45254.1 - 1.6e-64 218.4 0.0 3.4e-64 217.3 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KXL45255.1 - 5.5e-31 107.8 27.6 5.5e-31 107.8 27.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL45255.1 - 1.2e-15 57.4 6.4 1.2e-15 57.4 6.4 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KXL45255.1 - 1.3e-06 27.2 5.6 1.3e-06 27.2 5.6 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1269 PF06897.12 KXL45255.1 - 0.046 14.0 0.5 0.046 14.0 0.5 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1269) Usp PF00582.26 KXL45256.1 - 1e-21 77.9 4.7 1.5e-14 54.7 0.2 3.1 4 0 0 4 4 4 2 Universal stress protein family FAM27 PF15832.5 KXL45256.1 - 0.96 10.0 5.0 0.88 10.2 1.5 2.6 2 0 0 2 2 2 0 FAM27 D and E protein family DUF1100 PF06500.11 KXL45257.1 - 5.3e-14 51.8 0.0 6.7e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S15 PF02129.18 KXL45257.1 - 9.6e-08 31.9 0.0 1.7e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 KXL45257.1 - 1.6e-06 27.8 0.1 4.3e-06 26.4 0.1 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KXL45257.1 - 0.00081 18.7 0.0 0.012 14.9 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXL45257.1 - 0.0039 17.8 0.1 0.0069 17.0 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXL45257.1 - 0.01 15.5 0.1 0.86 9.2 0.1 2.4 1 1 1 2 2 2 0 alpha/beta hydrolase fold Esterase PF00756.20 KXL45257.1 - 0.015 15.0 0.0 0.045 13.4 0.0 1.8 1 1 0 1 1 1 0 Putative esterase TPR_2 PF07719.17 KXL45257.1 - 0.065 13.4 0.8 0.065 13.4 0.8 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXL45257.1 - 0.07 13.4 0.3 0.18 12.1 0.3 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat CDC45 PF02724.14 KXL45259.1 - 1e-132 443.6 0.0 1.2e-132 443.5 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein Abhydrolase_3 PF07859.13 KXL45260.1 - 3.3e-08 33.7 0.0 3.4e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KXL45261.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1992 PF09350.10 KXL45264.1 - 2.2e-20 72.6 0.8 4.6e-20 71.5 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) RPAP1_N PF08621.10 KXL45264.1 - 0.05 13.4 2.6 0.74 9.6 0.1 2.7 2 0 0 2 2 2 0 RPAP1-like, N-terminal CDV3 PF15359.6 KXL45264.1 - 0.089 13.3 0.3 0.089 13.3 0.3 2.3 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 YflT PF11181.8 KXL45264.1 - 0.3 11.6 2.1 27 5.3 0.0 2.5 2 0 0 2 2 2 0 Heat induced stress protein YflT FliG_C PF01706.16 KXL45264.1 - 0.55 10.5 3.2 6.5 7.0 0.2 2.9 2 1 0 2 2 2 0 FliG C-terminal domain Peptidase_M41 PF01434.18 KXL45269.1 - 2.2e-59 200.5 4.2 4.2e-59 199.6 4.2 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KXL45269.1 - 1.3e-43 148.6 0.0 3.6e-43 147.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXL45269.1 - 1.3e-09 37.7 0.0 2.7e-08 33.5 0.0 2.5 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 KXL45269.1 - 7.8e-07 29.2 0.1 3.2e-06 27.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXL45269.1 - 6.1e-06 26.7 2.5 0.00038 20.9 2.2 3.5 2 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 KXL45269.1 - 1.8e-05 24.2 0.0 7.5e-05 22.1 0.0 1.7 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_22 PF13401.6 KXL45269.1 - 8.2e-05 22.9 0.0 0.056 13.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KXL45269.1 - 8.3e-05 22.4 0.0 0.00018 21.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KXL45269.1 - 0.0047 17.1 0.0 0.016 15.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KXL45269.1 - 0.0097 15.7 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 KXL45269.1 - 0.012 15.8 0.0 0.042 13.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KXL45269.1 - 0.015 15.8 0.0 0.19 12.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 KXL45269.1 - 0.017 15.1 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KXL45269.1 - 0.02 14.2 0.1 0.046 13.1 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KXL45269.1 - 0.026 14.1 1.0 0.46 10.0 0.2 2.5 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.6 KXL45269.1 - 0.029 14.6 0.0 0.16 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KXL45269.1 - 0.07 12.3 0.0 0.31 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 KXL45269.1 - 0.079 12.5 0.1 0.34 10.4 0.1 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 KXL45269.1 - 0.084 12.2 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_17 PF13207.6 KXL45269.1 - 0.092 13.2 0.0 0.27 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KXL45269.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 KXL45269.1 - 0.12 11.8 0.2 0.43 10.0 0.2 1.9 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.6 KXL45269.1 - 0.12 12.0 0.2 0.83 9.3 0.1 2.4 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KXL45269.1 - 0.13 11.5 1.6 0.79 9.0 0.6 2.3 1 1 1 2 2 2 0 Zeta toxin NACHT PF05729.12 KXL45269.1 - 0.17 11.8 0.3 1.7 8.5 0.1 2.3 2 0 0 2 2 2 0 NACHT domain DUF4129 PF13559.6 KXL45270.1 - 0.00043 20.5 0.0 0.0022 18.2 0.0 2.2 2 1 1 3 3 3 1 Domain of unknown function (DUF4129) NICE-3 PF07406.11 KXL45270.1 - 0.048 13.7 0.0 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 NICE-3 protein Prenyltrans PF00432.21 KXL45271.1 - 2e-34 117.0 20.8 1.8e-08 34.0 0.5 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat PHD PF00628.29 KXL45272.1 - 6.6e-07 29.1 7.8 8e-07 28.9 7.8 1.1 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KXL45272.1 - 0.025 14.8 3.7 0.028 14.7 3.7 1.2 1 0 0 1 1 1 0 PHD-like zinc-binding domain F-box-like PF12937.7 KXL45273.1 - 0.0032 17.3 0.1 0.01 15.7 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXL45273.1 - 0.029 14.3 0.0 0.064 13.2 0.0 1.6 1 0 0 1 1 1 0 F-box domain p450 PF00067.22 KXL45274.1 - 2e-36 125.7 0.0 2.4e-35 122.2 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 RabGAP-TBC PF00566.18 KXL45275.1 - 6.4e-49 166.5 0.0 1.9e-48 165.0 0.0 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain ERM PF00769.19 KXL45275.1 - 0.059 13.2 47.9 0.029 14.2 16.9 3.3 2 1 1 3 3 3 0 Ezrin/radixin/moesin family MINDY_DUB PF04424.13 KXL45275.1 - 0.38 10.8 3.1 0.39 10.8 0.3 2.3 2 0 0 2 2 2 0 MINDY deubiquitinase betaPIX_CC PF16523.5 KXL45275.1 - 0.8 9.6 16.5 0.14 12.0 2.2 3.0 3 0 0 3 3 3 0 betaPIX coiled coil EntA_Immun PF08951.10 KXL45275.1 - 7 7.1 6.9 6.2 7.3 0.9 2.9 2 0 0 2 2 2 0 Enterocin A Immunity CDC45 PF02724.14 KXL45276.1 - 4e-20 71.7 0.3 4e-20 71.7 0.3 2.0 1 1 1 2 2 2 1 CDC45-like protein SR-25 PF10500.9 KXL45276.1 - 0.00024 20.8 8.6 0.00025 20.7 8.6 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF4614 PF15391.6 KXL45276.1 - 0.0033 17.5 4.3 0.0038 17.3 4.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4614) XRCC4 PF06632.12 KXL45276.1 - 0.024 13.5 3.8 0.025 13.4 3.8 1.0 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF4692 PF15763.5 KXL45276.1 - 0.1 13.0 2.4 0.12 12.9 2.4 1.1 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Cwf_Cwc_15 PF04889.12 KXL45276.1 - 0.14 11.9 5.0 0.16 11.7 5.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop53 PF07767.11 KXL45276.1 - 0.23 10.8 4.0 0.26 10.6 4.0 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CCDC106 PF15794.5 KXL45276.1 - 0.4 10.4 5.3 0.45 10.2 5.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 FRG1 PF06229.12 KXL45277.1 - 2.8e-42 144.6 3.7 7.5e-42 143.2 3.7 1.7 1 1 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 KXL45277.1 - 0.041 14.1 0.0 0.076 13.2 0.0 1.5 1 0 0 1 1 1 0 Fascin domain DUF155 PF02582.14 KXL45279.1 - 8.2e-49 166.1 0.1 4.9e-48 163.5 0.1 2.0 1 1 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 SecG PF03840.14 KXL45279.1 - 0.18 11.9 1.3 2.4 8.3 1.2 2.2 2 0 0 2 2 2 0 Preprotein translocase SecG subunit GST_N PF02798.20 KXL45280.1 - 1.4e-08 35.0 0.0 2.2e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXL45280.1 - 7.6e-08 32.7 0.0 1.5e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXL45280.1 - 3.5e-06 27.2 0.0 7.2e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXL45280.1 - 0.00012 22.2 0.0 0.00021 21.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXL45280.1 - 0.0034 17.6 0.0 0.0054 16.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXL45280.1 - 0.0034 17.4 0.3 0.011 15.8 0.1 1.9 1 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain 2-Hacid_dh_C PF02826.19 KXL45281.1 - 1.4e-43 148.3 0.0 2e-43 147.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXL45281.1 - 1e-08 34.9 0.0 1.2e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ELL PF10390.9 KXL45282.1 - 0.0038 16.8 0.0 0.0038 16.8 0.0 2.5 2 1 0 2 2 2 1 RNA polymerase II elongation factor ELL ABC_tran_2 PF16949.5 KXL45282.1 - 0.34 9.7 0.1 0.46 9.2 0.1 1.1 1 0 0 1 1 1 0 Putative ATP-binding cassette SLATT_fungal PF18142.1 KXL45283.1 - 7.8e-24 84.0 0.0 8.9e-24 83.8 0.0 1.0 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain DUF3431 PF11913.8 KXL45284.1 - 5.9e-80 268.1 0.4 6.7e-80 267.9 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Glyco_transf_28 PF03033.20 KXL45285.1 - 1.1e-16 61.2 0.5 3.1e-11 43.5 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KXL45285.1 - 8.2e-08 31.5 0.4 4.8e-07 28.9 0.0 2.0 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 KXL45285.1 - 8.1e-05 22.9 0.1 0.00028 21.2 0.1 1.9 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Glyco_tran_28_C PF04101.16 KXL45285.1 - 0.0024 17.9 0.0 0.048 13.6 0.0 2.6 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain Kelch_4 PF13418.6 KXL45286.1 - 1.1e-24 86.2 7.4 1.8e-06 27.9 0.0 5.6 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KXL45286.1 - 1.5e-24 85.5 1.8 1.5e-07 31.2 0.0 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 KXL45286.1 - 1.1e-21 76.3 2.6 2.2e-06 27.8 0.1 5.7 3 1 2 5 5 5 4 Kelch motif Kelch_2 PF07646.15 KXL45286.1 - 9.2e-16 57.1 6.2 5.4e-06 26.2 0.3 4.9 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 KXL45286.1 - 9.6e-16 57.1 0.5 0.00011 21.7 0.1 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 KXL45286.1 - 4.3e-15 55.6 7.9 1.6e-05 25.1 0.0 6.1 6 0 0 6 6 6 2 Galactose oxidase, central domain BTB PF00651.31 KXL45286.1 - 6.7e-12 45.6 0.0 1.2e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain ANAPC4_WD40 PF12894.7 KXL45287.1 - 3.9e-17 62.3 6.3 3.6e-06 27.2 0.1 4.3 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXL45287.1 - 3.3e-16 59.4 15.6 0.00053 20.7 0.1 6.3 6 1 0 6 6 6 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KXL45287.1 - 3.3e-07 29.6 0.1 0.00015 20.9 0.0 3.4 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KXL45287.1 - 1.6e-05 24.9 0.1 0.021 14.7 0.1 2.6 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A TPR_2 PF07719.17 KXL45288.1 - 0.06 13.5 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat CDC37_M PF08565.11 KXL45288.1 - 0.086 12.8 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 Cdc37 Hsp90 binding domain TPR_7 PF13176.6 KXL45288.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4850 PF16142.5 KXL45288.1 - 0.13 11.7 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4850) Bromodomain PF00439.25 KXL45290.1 - 3.2e-24 84.8 0.1 5.7e-24 84.0 0.1 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KXL45290.1 - 7.1e-08 32.7 0.0 1.3e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXL45290.1 - 4e-06 26.8 0.3 1.2e-05 25.3 0.2 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXL45290.1 - 0.0014 19.1 0.0 0.003 18.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ost5 PF05251.12 KXL45291.1 - 5e-20 71.5 7.8 5.9e-20 71.3 7.8 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 DUF997 PF06196.12 KXL45291.1 - 0.14 12.2 1.4 0.16 12.0 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF997) Rad1 PF02144.16 KXL45292.1 - 7.2e-67 225.3 0.0 8.3e-67 225.1 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 PCNA_C PF02747.15 KXL45292.1 - 0.00069 19.8 0.2 0.023 14.8 0.1 2.2 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain RHS_repeat PF05593.14 KXL45292.1 - 0.025 15.1 0.3 0.12 12.9 0.0 2.2 2 0 0 2 2 2 0 RHS Repeat NAD_binding_3 PF03447.16 KXL45292.1 - 0.047 14.4 0.1 0.11 13.2 0.1 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Zn_clus PF00172.18 KXL45293.1 - 5.5e-06 26.4 6.6 8.8e-06 25.8 6.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_isomerase PF00160.21 KXL45294.1 - 3.4e-37 128.2 0.0 5.2e-37 127.6 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KXL45294.1 - 1.6e-16 59.9 0.0 3.5e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LAM_C PF12544.8 KXL45295.1 - 0.00023 21.3 0.1 0.00046 20.4 0.1 1.4 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Fer4_14 PF13394.6 KXL45295.1 - 0.00045 20.3 0.0 0.00072 19.7 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Radical_SAM PF04055.21 KXL45295.1 - 0.00095 19.6 0.0 0.002 18.5 0.0 1.6 1 1 0 1 1 1 1 Radical SAM superfamily Cypo_polyhedrin PF05865.11 KXL45295.1 - 0.0051 16.2 0.0 0.013 15.0 0.0 1.5 1 1 1 2 2 2 1 Cypovirus polyhedrin protein HTH_Tnp_Tc5 PF03221.16 KXL45297.1 - 0.00027 20.9 0.0 0.00053 20.0 0.0 1.6 1 1 0 1 1 1 1 Tc5 transposase DNA-binding domain RNA_pol_Rpb1_1 PF04997.12 KXL45298.1 - 0.093 12.1 0.0 0.096 12.0 0.0 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 Aldedh PF00171.22 KXL45299.1 - 2.6e-154 514.2 0.0 2.9e-154 514.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GDI PF00996.18 KXL45300.1 - 1.9e-193 642.9 0.0 2.2e-193 642.7 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 KXL45300.1 - 0.095 12.9 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXL45300.1 - 0.15 12.7 0.1 3 8.5 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Kelch_6 PF13964.6 KXL45301.1 - 1.4e-07 31.5 11.7 0.0001 22.5 0.0 5.5 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.6 KXL45301.1 - 2.5e-06 27.3 14.1 3.4e-05 23.7 0.4 4.8 4 1 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 KXL45301.1 - 3.4e-06 26.5 10.8 0.021 14.4 0.0 4.7 4 0 0 4 4 4 2 Kelch motif Syndecan PF01034.20 KXL45301.1 - 0.011 15.7 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain Phage_HK97_TLTM PF06120.11 KXL45301.1 - 0.042 13.0 0.1 0.065 12.4 0.1 1.2 1 0 0 1 1 1 0 Tail length tape measure protein Kelch_4 PF13418.6 KXL45301.1 - 0.065 13.3 12.0 1.3 9.1 0.2 5.0 4 1 0 4 4 4 0 Galactose oxidase, central domain SKG6 PF08693.10 KXL45301.1 - 0.074 12.5 1.0 0.17 11.3 1.0 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Kelch_3 PF13415.6 KXL45301.1 - 0.074 13.4 8.2 9.7 6.6 0.1 5.2 5 0 0 5 5 5 0 Galactose oxidase, central domain Kelch_2 PF07646.15 KXL45301.1 - 0.37 10.9 10.9 4.8 7.3 0.0 5.7 5 1 0 5 5 5 0 Kelch motif MRP-L47 PF06984.13 KXL45302.1 - 3.2e-17 62.4 0.1 5.1e-17 61.8 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) MR_MLE_C PF13378.6 KXL45303.1 - 5.9e-56 189.5 0.0 8.8e-56 188.9 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KXL45303.1 - 0.0065 15.6 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus PepSY PF03413.19 KXL45303.1 - 0.084 13.4 0.4 0.27 11.8 0.4 1.9 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain MR_MLE_N PF02746.16 KXL45303.1 - 0.093 12.9 0.0 0.28 11.4 0.0 1.8 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Cmc1 PF08583.10 KXL45304.1 - 2.8e-11 43.3 17.0 2.3e-10 40.3 17.0 2.0 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 KXL45304.1 - 0.00038 20.5 1.2 0.0011 19.1 1.2 1.7 1 1 0 1 1 1 1 CHCH domain CX9C PF16860.5 KXL45304.1 - 0.0024 17.8 1.7 0.0047 16.9 1.7 1.4 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF2721 PF11026.8 KXL45305.1 - 0.0021 18.0 2.2 0.0058 16.5 0.4 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2721) CrgA PF06781.12 KXL45305.1 - 0.0036 17.3 0.5 0.017 15.2 0.5 2.1 1 1 0 1 1 1 1 Cell division protein CrgA TMEM189_B_dmain PF10520.9 KXL45305.1 - 0.0039 17.3 0.4 0.0078 16.3 0.2 1.5 1 1 0 1 1 1 1 B domain of TMEM189, localisation domain SLAC1 PF03595.17 KXL45305.1 - 0.012 14.9 0.3 0.018 14.3 0.3 1.1 1 0 0 1 1 1 0 Voltage-dependent anion channel SNARE PF05739.19 KXL45305.1 - 0.051 13.6 0.2 0.051 13.6 0.2 1.9 2 0 0 2 2 2 0 SNARE domain DUF2157 PF09925.9 KXL45305.1 - 0.057 13.2 0.0 0.09 12.6 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) NMN_transporter PF04973.12 KXL45305.1 - 0.065 13.2 0.7 0.093 12.7 0.7 1.1 1 0 0 1 1 1 0 Nicotinamide mononucleotide transporter DUF1345 PF07077.11 KXL45305.1 - 0.083 12.6 0.5 0.14 11.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) DUF4191 PF13829.6 KXL45305.1 - 0.1 11.9 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF3169 PF11368.8 KXL45305.1 - 0.17 11.4 0.0 0.24 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) WD40 PF00400.32 KXL45307.1 - 3.3e-38 129.0 12.4 4e-06 27.5 0.0 7.4 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL45307.1 - 1.2e-13 51.2 0.1 0.00016 21.9 0.0 4.7 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXL45307.1 - 0.0059 16.5 0.0 0.9 9.4 0.0 2.8 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KXL45307.1 - 0.032 12.8 0.2 0.18 10.3 0.0 2.2 2 1 2 4 4 4 0 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 KXL45307.1 - 0.043 12.8 0.0 16 4.3 0.0 3.3 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KXL45307.1 - 0.12 11.0 0.1 4.5 5.9 0.0 2.2 2 0 0 2 2 2 0 Nup133 N terminal like TRAPP PF04051.16 KXL45308.1 - 2.4e-33 114.9 0.0 3e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PNGaseA PF12222.8 KXL45308.1 - 0.18 10.6 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A LisH PF08513.11 KXL45309.1 - 0.23 11.5 0.1 0.4 10.7 0.1 1.4 1 0 0 1 1 1 0 LisH Bap31 PF05529.12 KXL45310.1 - 1.8e-44 150.9 5.1 2.2e-44 150.6 5.1 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KXL45310.1 - 7.1e-12 45.1 1.4 2e-11 43.7 0.1 2.2 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain DUF4349 PF14257.6 KXL45310.1 - 0.097 12.1 0.3 0.17 11.3 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF603 PF04645.12 KXL45310.1 - 0.11 12.2 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF603 DivIC PF04977.15 KXL45310.1 - 0.16 11.8 9.9 0.74 9.6 0.4 3.6 2 2 2 4 4 4 0 Septum formation initiator Dus PF01207.17 KXL45311.1 - 2.8e-36 125.2 0.1 5e-26 91.5 0.1 2.7 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) Toxin_20 PF08089.11 KXL45311.1 - 0.23 11.6 5.1 0.89 9.7 4.4 2.5 2 0 0 2 2 2 0 Huwentoxin-II family zf-C2H2_aberr PF17017.5 KXL45312.1 - 0.00058 20.0 5.2 0.025 14.7 0.0 2.6 3 0 0 3 3 3 2 Aberrant zinc-finger zf-C2H2_4 PF13894.6 KXL45312.1 - 0.002 18.8 14.5 0.03 15.2 1.5 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KXL45312.1 - 0.0039 17.6 15.3 0.06 13.8 0.7 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXL45312.1 - 0.006 17.0 12.2 0.0068 16.8 0.6 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-BED PF02892.15 KXL45312.1 - 0.41 10.7 3.2 2.1 8.4 0.1 2.5 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_jaz PF12171.8 KXL45312.1 - 0.54 10.6 6.1 3.9 7.9 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 KXL45312.1 - 4.4 7.0 5.9 8.8 6.1 0.1 3.1 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Amidase PF01425.21 KXL45313.1 - 3.9e-77 260.1 0.0 4.2e-76 256.7 0.0 1.9 1 1 0 1 1 1 1 Amidase WD40 PF00400.32 KXL45315.1 - 5.9e-12 45.9 1.0 0.014 16.2 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL45315.1 - 0.00082 19.6 0.0 0.62 10.4 0.0 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KXL45315.1 - 0.01 16.3 1.8 6.9 7.3 0.1 3.3 3 0 0 3 3 3 0 PQQ-like domain Transp_cyt_pur PF02133.15 KXL45316.1 - 5.4e-42 144.1 3.4 7.2e-42 143.7 3.4 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Epiglycanin_C PF14654.6 KXL45316.1 - 0.98 9.5 4.7 0.25 11.4 1.5 1.7 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region DDE_1 PF03184.19 KXL45317.1 - 1.1e-06 28.4 0.1 3.3e-06 26.9 0.1 1.6 1 1 1 2 2 2 1 DDE superfamily endonuclease IGF2_C PF08365.11 KXL45318.1 - 0.082 12.9 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Insulin-like growth factor II E-peptide SNF2_N PF00176.23 KXL45319.1 - 4.1e-38 131.0 0.0 1.8e-35 122.3 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KXL45319.1 - 0.00013 22.3 0.1 0.00025 21.4 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Utp12 PF04003.12 KXL45320.1 - 2.8e-19 69.4 0.2 2.8e-19 69.4 0.2 1.7 2 0 0 2 2 2 1 Dip2/Utp12 Family Bromodomain PF00439.25 KXL45321.1 - 5e-43 145.1 0.4 2.1e-20 72.6 0.0 2.8 3 0 0 3 3 3 2 Bromodomain BET PF17035.5 KXL45321.1 - 1.1e-12 47.9 1.0 2.9e-12 46.6 1.0 1.8 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Csm1_N PF18504.1 KXL45321.1 - 0.28 11.5 4.5 14 6.1 0.2 3.6 3 0 0 3 3 3 0 Csm1 N-terminal domain 6PF2K PF01591.18 KXL45322.1 - 6.7e-79 264.3 0.0 9e-79 263.9 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KXL45322.1 - 1.8e-34 119.2 0.0 2.8e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KXL45322.1 - 5.3e-05 23.4 0.0 0.00011 22.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KXL45322.1 - 0.0016 17.9 0.1 0.0024 17.4 0.1 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 DUF4248 PF14053.6 KXL45322.1 - 0.05 13.6 0.0 0.62 10.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) DUF3425 PF11905.8 KXL45324.1 - 1.1e-12 48.1 0.3 2.2e-12 47.0 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) BMP2K_C PF15282.6 KXL45324.1 - 0.017 15.0 0.2 0.026 14.4 0.2 1.2 1 0 0 1 1 1 0 BMP-2-inducible protein kinase C-terminus bZIP_1 PF00170.21 KXL45324.1 - 0.23 11.6 9.5 0.46 10.6 9.5 1.5 1 0 0 1 1 1 0 bZIP transcription factor Rnk_N PF14760.6 KXL45324.1 - 6.3 7.4 6.8 12 6.5 6.8 1.4 1 0 0 1 1 1 0 Rnk N-terminus AAA PF00004.29 KXL45325.1 - 1.8e-18 67.2 0.0 3.4e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 KXL45325.1 - 4.5e-05 23.3 0.0 8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 KXL45325.1 - 0.0025 18.2 0.0 0.0072 16.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXL45325.1 - 0.0029 17.9 0.1 0.008 16.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 KXL45325.1 - 0.054 13.4 0.0 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 KXL45325.1 - 0.067 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Torsin PF06309.11 KXL45325.1 - 0.092 12.9 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Torsin ATPase_2 PF01637.18 KXL45325.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KXL45325.1 - 0.13 12.6 0.0 0.33 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 KXL45325.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KXL45325.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_33 PF13671.6 KXL45325.1 - 0.19 11.9 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Acyl-CoA_dh_1 PF00441.24 KXL45326.1 - 3.8e-37 127.8 0.8 4.9e-37 127.4 0.8 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 KXL45326.1 - 8.1e-12 45.6 0.1 1.1e-11 45.1 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DEAD_2 PF06733.15 KXL45326.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 DEAD_2 cNMP_binding PF00027.29 KXL45327.1 - 1.1e-32 111.9 0.0 1e-19 70.4 0.0 3.6 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain cNMPbd_u2 PF16643.5 KXL45327.1 - 8.2e-26 91.3 7.7 8.2e-26 91.3 7.7 2.2 3 0 0 3 3 3 1 Unstructured region on cNMP-binding protein LRR_6 PF13516.6 KXL45327.1 - 9.7e-10 37.7 4.0 4.5 7.6 0.0 8.1 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.7 KXL45327.1 - 1.7e-06 28.2 2.6 1.3 9.5 0.1 6.0 4 1 3 8 8 8 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KXL45327.1 - 3.3e-06 26.9 0.9 8.8e-06 25.5 0.3 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXL45327.1 - 1.7e-05 24.6 1.8 5.1e-05 23.0 0.3 2.7 3 0 0 3 3 3 1 F-box domain LRR_1 PF00560.33 KXL45327.1 - 0.014 15.8 16.6 1.3e+02 3.8 0.0 9.0 10 1 0 10 10 10 0 Leucine Rich Repeat Glyco_hydro_3_C PF01915.22 KXL45329.1 - 1.5e-40 139.3 0.0 2.3e-40 138.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXL45329.1 - 2.7e-34 119.0 0.0 4.2e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain WSC PF01822.19 KXL45329.1 - 1e-15 57.7 13.4 2.9e-15 56.2 13.4 1.9 1 0 0 1 1 1 1 WSC domain Fn3-like PF14310.6 KXL45329.1 - 1.3e-08 34.8 0.0 4e-08 33.3 0.0 1.8 2 0 0 2 2 2 1 Fibronectin type III-like domain Fungal_trans PF04082.18 KXL45330.1 - 1.9e-16 59.9 0.0 3.2e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL45330.1 - 7.1e-10 38.8 12.4 1.7e-09 37.6 12.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transp_cyt_pur PF02133.15 KXL45331.1 - 4.9e-46 157.4 43.9 6.3e-46 157.0 43.9 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin zf-RING_2 PF13639.6 KXL45332.1 - 0.00016 21.9 10.4 0.00016 21.9 10.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KXL45332.1 - 0.00028 20.7 9.2 0.00064 19.5 9.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXL45332.1 - 0.0044 16.8 9.2 0.0044 16.8 9.2 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KXL45332.1 - 0.0052 16.5 8.3 0.0052 16.5 8.3 1.7 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 KXL45332.1 - 0.019 15.0 6.5 0.019 15.0 6.5 1.9 2 0 0 2 2 2 0 RING-type zinc-finger Baculo_IE-1 PF05290.11 KXL45332.1 - 0.082 12.9 5.0 0.22 11.5 5.0 1.7 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_5 PF14634.6 KXL45332.1 - 0.1 12.6 11.4 0.21 11.6 11.4 1.6 1 0 0 1 1 1 0 zinc-RING finger domain AcetylCoA_hydro PF02550.15 KXL45332.1 - 0.16 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase N-terminal domain zf-C3HC4 PF00097.25 KXL45332.1 - 0.38 10.7 11.5 0.88 9.5 11.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXL45332.1 - 0.47 10.6 8.7 1.4 9.1 8.7 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Myb_DNA-binding PF00249.31 KXL45335.1 - 0.00049 20.2 0.0 0.0008 19.6 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Sigma70_r4_2 PF08281.12 KXL45335.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 Myb_DNA-bind_6 PF13921.6 KXL45336.1 - 4.7e-10 39.6 0.0 3.7e-07 30.3 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KXL45336.1 - 6.3e-09 35.9 0.0 0.00049 20.2 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Sigma70_r4_2 PF08281.12 KXL45336.1 - 0.15 11.8 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Myb_DNA-binding PF00249.31 KXL45337.1 - 1.6e-16 60.2 2.2 4.9e-10 39.4 0.4 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXL45337.1 - 4.6e-11 42.8 0.6 2.6e-05 24.4 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KXL45337.1 - 0.0077 16.1 0.3 0.015 15.2 0.1 1.5 1 1 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 KXL45337.1 - 0.086 13.0 0.4 0.4 10.9 0.1 2.1 1 1 1 2 2 2 0 Rap1 Myb domain DUF498 PF04430.14 KXL45339.1 - 2.3e-30 104.9 0.1 4.3e-30 104.0 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) PH_TFIIH PF08567.11 KXL45339.1 - 0.037 14.3 0.0 0.071 13.4 0.0 1.4 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain Ribosomal_L34e PF01199.18 KXL45340.1 - 3.1e-42 142.8 3.7 4.5e-42 142.3 3.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e zf-C2H2_3 PF13878.6 KXL45340.1 - 0.19 11.6 1.1 4.3 7.2 0.1 2.2 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO PROCN PF08083.11 KXL45341.1 - 9.3e-235 778.8 9.1 9.3e-235 778.8 9.1 2.1 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 KXL45341.1 - 1.4e-127 424.1 1.9 2.6e-127 423.2 1.9 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 KXL45341.1 - 8.4e-89 295.6 2.2 2.8e-88 293.9 2.2 2.0 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 KXL45341.1 - 9.7e-82 272.4 3.0 2.5e-81 271.0 3.0 1.8 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 KXL45341.1 - 3.9e-71 237.4 0.1 7.8e-71 236.4 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 KXL45341.1 - 4.4e-47 158.4 0.6 1.2e-46 157.0 0.6 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 KXL45341.1 - 3.8e-45 152.8 0.0 1e-44 151.4 0.0 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain HTH_Tnp_Tc5 PF03221.16 KXL45342.1 - 0.00016 21.7 0.0 0.00016 21.6 0.0 1.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain RVT_2 PF07727.14 KXL45343.1 - 2.6e-27 96.0 0.0 4.4e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Actin PF00022.19 KXL45344.1 - 9.3e-127 423.0 0.0 4.1e-126 420.9 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KXL45344.1 - 0.00057 18.8 0.0 0.21 10.3 0.0 2.7 2 1 0 2 2 2 2 MreB/Mbl protein DUF4692 PF15763.5 KXL45344.1 - 0.0014 19.1 0.1 0.0022 18.5 0.1 1.2 1 0 0 1 1 1 1 Regulator of human erythroid cell expansion (RHEX) DUF3602 PF12223.8 KXL45345.1 - 4.2e-14 52.9 8.7 1.9e-12 47.6 0.1 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) Sec3_C PF09763.9 KXL45345.1 - 0.093 11.1 0.0 0.1 10.9 0.0 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 ADH_zinc_N PF00107.26 KXL45346.1 - 5.2e-08 32.9 0.0 8e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXL45346.1 - 2.5e-07 30.6 1.1 4.7e-07 29.7 0.1 2.0 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXL45346.1 - 0.13 13.3 0.0 0.2 12.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Iso_dh PF00180.20 KXL45347.1 - 5.8e-75 252.6 0.0 6.8e-75 252.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SLATT_fungal PF18142.1 KXL45349.1 - 1.2e-15 57.6 0.8 1.7e-15 57.1 0.7 1.3 1 1 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain ArsP_2 PF11449.8 KXL45349.1 - 0.044 13.0 0.1 0.053 12.7 0.1 1.2 1 0 0 1 1 1 0 Putative, 10TM heavy-metal exporter Flavodoxin_1 PF00258.25 KXL45349.1 - 0.12 12.6 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin NMT1 PF09084.11 KXL45350.1 - 2.2e-77 259.9 0.0 3.1e-77 259.4 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 KXL45350.1 - 7.5e-06 25.8 0.0 0.64 9.7 0.0 3.7 3 1 1 4 4 4 2 NMT1-like family GAS PF13851.6 KXL45350.1 - 0.069 12.5 0.2 0.13 11.6 0.2 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF5011 PF16403.5 KXL45351.1 - 0.078 13.1 0.1 0.28 11.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5011) UBA_4 PF14555.6 KXL45353.1 - 1.8e-06 27.6 0.5 3.3e-06 26.8 0.5 1.4 1 0 0 1 1 1 1 UBA-like domain LysM PF01476.20 KXL45353.1 - 0.0046 17.0 0.0 0.0069 16.4 0.0 1.3 1 0 0 1 1 1 1 LysM domain TAP_C PF03943.13 KXL45353.1 - 0.23 11.1 1.7 0.47 10.1 0.4 2.0 2 0 0 2 2 2 0 TAP C-terminal domain zf-RING_2 PF13639.6 KXL45353.1 - 0.39 11.1 8.0 0.9 9.9 8.0 1.7 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.6 KXL45353.1 - 0.96 9.4 12.6 5.2 7.0 12.6 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXL45353.1 - 3.9 7.5 11.6 7.8 6.6 10.3 2.3 2 1 0 2 2 2 0 zinc-RING finger domain FA_hydroxylase PF04116.13 KXL45354.1 - 2e-22 79.9 12.8 2e-22 79.9 12.8 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily L_HMGIC_fpl PF10242.9 KXL45355.1 - 5.8e-05 23.4 6.7 0.00057 20.1 7.5 1.8 1 1 1 2 2 2 1 Lipoma HMGIC fusion partner-like protein DUF2516 PF10724.9 KXL45355.1 - 0.32 11.3 0.1 0.32 11.3 0.1 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2516) IBR PF01485.21 KXL45357.1 - 0.096 12.9 2.5 1.5 9.1 1.3 2.1 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-C2H2_4 PF13894.6 KXL45357.1 - 7.9 7.6 12.6 18 6.5 0.4 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger TRP PF06011.12 KXL45362.1 - 1.1e-165 551.6 28.8 1.3e-165 551.3 28.8 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KXL45362.1 - 9.6e-40 136.2 1.3 1.6e-39 135.4 1.3 1.4 1 0 0 1 1 1 1 ML-like domain DUF2981 PF11200.8 KXL45362.1 - 0.029 14.1 0.4 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2981) UAA PF08449.11 KXL45364.1 - 0.094 11.9 0.0 0.11 11.7 0.0 1.0 1 0 0 1 1 1 0 UAA transporter family Gln-synt_C PF00120.24 KXL45365.1 - 8.9e-18 64.4 0.0 8.6e-15 54.6 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KXL45365.1 - 1.4e-10 40.8 0.0 2.4e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Aminotran_4 PF01063.19 KXL45366.1 - 1.2e-22 80.9 0.0 1.8e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV CopK PF11525.8 KXL45366.1 - 0.1 12.3 0.1 0.42 10.3 0.0 2.0 2 0 0 2 2 2 0 Copper resistance protein K SH3_1 PF00018.28 KXL45368.1 - 5.9e-15 54.6 0.0 9.1e-15 54.0 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXL45368.1 - 4.7e-11 42.4 0.0 9.8e-11 41.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXL45368.1 - 1.4e-08 34.3 0.0 2.5e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Oxysterol_BP PF01237.18 KXL45369.1 - 3e-112 375.2 0.0 1.5e-111 372.8 0.0 1.9 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 KXL45369.1 - 5.4e-38 129.2 0.1 1.5e-37 127.7 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KXL45369.1 - 2.1e-06 28.2 0.0 5e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 PH domain GOLD_2 PF13897.6 KXL45369.1 - 0.12 12.8 0.0 0.35 11.4 0.0 1.8 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking PDEase_I PF00233.19 KXL45370.1 - 2.1e-70 237.1 0.0 2.4e-70 236.9 0.0 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 KXL45370.1 - 0.014 15.7 0.0 0.025 14.8 0.0 1.7 1 1 0 1 1 1 0 HD domain Myb_DNA-bind_6 PF13921.6 KXL45371.1 - 2.1e-05 24.7 0.3 6.8e-05 23.0 0.1 1.9 1 1 1 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KXL45371.1 - 2.6e-05 24.3 1.7 0.0002 21.5 0.0 2.3 2 1 0 2 2 2 1 Myb-like DNA-binding domain Cation_efflux PF01545.21 KXL45372.1 - 3.9e-48 163.8 7.2 4.8e-48 163.5 7.2 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KXL45372.1 - 0.0011 19.1 0.1 0.0025 17.9 0.1 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Fungal_trans PF04082.18 KXL45373.1 - 2.6e-09 36.5 2.3 3.9e-09 35.9 2.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL45373.1 - 9.7e-08 32.0 9.4 1.7e-07 31.3 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IMUP PF15761.5 KXL45374.1 - 3.7 8.3 19.6 0.42 11.3 8.0 2.6 2 0 0 2 2 2 0 Immortalisation up-regulated protein zf-HC5HC2H_2 PF13832.6 KXL45375.1 - 1.4e-31 108.9 6.9 1.4e-31 108.9 6.9 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 KXL45375.1 - 1.1e-29 103.9 0.2 1.1e-29 103.9 0.2 2.4 2 1 0 2 2 2 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 KXL45375.1 - 1e-26 93.0 4.7 1e-26 93.0 4.7 2.8 2 1 0 2 2 2 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KXL45375.1 - 1e-13 50.6 1.3 1e-13 50.6 1.3 2.6 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 KXL45375.1 - 7.3e-10 38.6 22.3 2.9e-09 36.7 9.6 2.7 2 0 0 2 2 2 2 PHD-finger DUF3150 PF11348.8 KXL45375.1 - 0.021 14.0 0.7 0.035 13.3 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) GCIP PF13324.6 KXL45375.1 - 0.027 14.1 1.8 0.059 13.0 1.8 1.5 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting TINF2_N PF14973.6 KXL45375.1 - 0.39 11.1 2.5 0.44 10.9 0.6 2.1 3 0 0 3 3 3 0 TERF1-interacting nuclear factor 2 N-terminus zf-RING-like PF08746.11 KXL45375.1 - 1.5 9.2 19.2 0.035 14.4 5.9 2.8 2 1 0 2 2 2 0 RING-like domain CCDC-167 PF15188.6 KXL45375.1 - 4.3 7.8 6.6 3.5 8.0 2.7 2.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 PQ-loop PF04193.14 KXL45376.1 - 1.6e-15 56.6 0.5 1.6e-15 56.6 0.5 1.7 2 0 0 2 2 2 1 PQ loop repeat YqhR PF11085.8 KXL45376.1 - 0.043 13.7 0.1 0.072 13.0 0.1 1.3 1 0 0 1 1 1 0 Conserved membrane protein YqhR GMC_oxred_N PF00732.19 KXL45383.1 - 9.5e-12 44.9 0.0 2.8e-11 43.3 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase Sugar_tr PF00083.24 KXL45384.1 - 2.4e-22 79.5 24.7 7.8e-15 54.7 8.3 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter NAAA-beta PF15508.6 KXL45384.1 - 0.19 12.0 0.5 0.82 10.0 0.2 2.3 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Fungal_trans PF04082.18 KXL45385.1 - 9e-08 31.5 0.2 1.6e-07 30.6 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL45385.1 - 0.013 15.6 0.5 0.027 14.6 0.5 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain FcoT PF10862.8 KXL45385.1 - 0.081 12.5 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 FcoT-like thioesterase domain Cupin_2 PF07883.11 KXL45386.1 - 1.5e-08 34.2 0.0 2.7e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KXL45386.1 - 0.00017 21.2 0.0 0.00031 20.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_6 PF12852.7 KXL45386.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Cupin FAD_binding_3 PF01494.19 KXL45387.1 - 2.1e-24 86.4 0.0 2.9e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain ADC PF06314.11 KXL45387.1 - 8.1e-14 51.8 0.0 1.3e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) NAD_binding_8 PF13450.6 KXL45387.1 - 1.5e-06 28.4 0.3 3.1e-06 27.3 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXL45387.1 - 1e-05 24.9 2.9 5.4e-05 22.6 2.9 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXL45387.1 - 3.7e-05 23.0 1.8 6.1e-05 22.3 1.2 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXL45387.1 - 0.00012 21.8 4.5 0.016 14.8 2.0 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KXL45387.1 - 0.005 16.2 0.3 0.01 15.2 0.3 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXL45387.1 - 0.015 14.1 1.2 0.015 14.1 0.1 1.5 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 KXL45387.1 - 0.02 14.0 0.1 0.03 13.4 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 KXL45387.1 - 0.032 13.5 0.2 0.062 12.5 0.2 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 KXL45387.1 - 0.05 14.2 1.0 0.22 12.1 0.5 2.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXL45387.1 - 0.06 12.2 0.9 0.27 10.0 0.2 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 KXL45387.1 - 0.09 12.0 0.5 0.15 11.2 0.5 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short_C2 PF13561.6 KXL45388.1 - 6.2e-54 183.0 0.0 7.6e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL45388.1 - 4e-45 153.7 0.0 5e-45 153.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL45388.1 - 1.1e-09 38.4 0.0 2.9e-09 37.1 0.0 1.5 2 0 0 2 2 2 1 KR domain DFP PF04127.15 KXL45388.1 - 0.0049 16.7 1.2 0.015 15.1 1.2 1.7 1 1 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein YjeF_N PF03853.15 KXL45388.1 - 0.0055 16.6 0.0 0.011 15.6 0.0 1.5 1 1 0 1 1 1 1 YjeF-related protein N-terminus Pyr_redox_3 PF13738.6 KXL45388.1 - 0.2 10.8 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.18 KXL45389.1 - 2.8e-15 56.1 0.1 5.2e-15 55.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL45389.1 - 1.2e-06 28.6 7.7 1.2e-06 28.6 7.7 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KXL45389.1 - 0.0011 19.3 2.9 0.0016 18.8 1.6 2.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXL45389.1 - 0.074 13.9 0.4 0.074 13.9 0.4 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXL45389.1 - 0.078 13.0 0.4 0.24 11.4 0.3 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger MFS_1 PF07690.16 KXL45390.1 - 2.9e-33 115.3 28.1 2.9e-33 115.3 28.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL45390.1 - 2.8e-16 59.5 9.3 2.8e-16 59.5 9.3 2.9 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXL45390.1 - 2.6e-06 26.2 5.4 5e-06 25.2 5.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FAD_binding_4 PF01565.23 KXL45391.1 - 5e-29 100.8 0.1 7.4e-29 100.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Cu_amine_oxid PF01179.20 KXL45392.1 - 1.9e-156 521.1 0.0 2.3e-156 520.9 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KXL45392.1 - 0.00048 20.3 0.1 0.00094 19.4 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 KXL45392.1 - 0.0013 19.1 0.0 0.0026 18.2 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain GFO_IDH_MocA_C PF02894.17 KXL45393.1 - 1.1e-19 70.5 0.1 3.5e-19 68.9 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.22 KXL45393.1 - 4.7e-19 69.4 0.0 8.9e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KXL45393.1 - 0.1 13.3 0.0 0.16 12.7 0.0 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain NYN PF01936.18 KXL45393.1 - 0.15 12.5 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 NYN domain HD_3 PF13023.6 KXL45394.1 - 3.7e-50 170.1 0.2 6e-50 169.4 0.2 1.3 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KXL45394.1 - 8.3e-12 45.2 0.4 1.3e-11 44.6 0.1 1.4 2 0 0 2 2 2 1 HD containing hydrolase-like enzyme HD PF01966.22 KXL45394.1 - 0.054 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 HD domain Bot1p PF12298.8 KXL45394.1 - 0.92 9.7 5.0 6.6 6.9 0.8 2.4 2 0 0 2 2 2 0 Eukaryotic mitochondrial regulator protein HAUS6_N PF14661.6 KXL45395.1 - 7.9e-40 136.9 1.0 1.9e-39 135.6 1.0 1.6 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus Erg28 PF03694.13 KXL45396.1 - 3e-45 153.1 1.7 3.9e-45 152.7 1.7 1.2 1 0 0 1 1 1 1 Erg28 like protein TIM PF00121.18 KXL45397.1 - 5.2e-54 183.2 0.0 5.9e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase MTHFR PF02219.17 KXL45398.1 - 2e-108 362.1 0.0 2.8e-108 361.6 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase TENA_THI-4 PF03070.16 KXL45400.1 - 2.2e-10 40.7 0.1 3.4e-10 40.1 0.1 1.3 1 1 0 1 1 1 1 TENA/THI-4/PQQC family Glyco_hydro_35 PF01301.19 KXL45401.1 - 1.1e-86 291.3 0.1 2e-86 290.5 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 KXL45401.1 - 3.3e-58 196.5 0.2 5.2e-58 195.8 0.2 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 KXL45401.1 - 5.5e-54 181.6 7.1 1.3e-32 112.7 0.5 2.8 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 KXL45401.1 - 6e-21 73.8 0.0 3e-20 71.6 0.0 2.2 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 CUE PF02845.16 KXL45402.1 - 2.5e-07 30.3 0.0 3.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 CUE domain NOT2_3_5 PF04153.18 KXL45403.1 - 3e-26 92.1 0.0 3.4e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Imm51 PF15595.6 KXL45403.1 - 0.01 15.8 0.0 0.037 14.0 0.0 1.7 1 1 1 2 2 2 0 Immunity protein 51 AIRC PF00731.20 KXL45405.1 - 1.1e-56 190.5 4.1 2e-56 189.7 4.1 1.5 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 KXL45405.1 - 3.8e-49 166.6 0.0 5.9e-49 165.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 KXL45405.1 - 3.9e-18 64.9 0.4 9e-18 63.7 0.4 1.7 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 KXL45405.1 - 0.0075 15.8 0.0 0.042 13.4 0.0 2.1 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus 2-Hacid_dh_C PF02826.19 KXL45405.1 - 0.0077 15.6 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KXL45405.1 - 0.0092 15.3 0.1 0.019 14.3 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain CPSase_L_D2 PF02786.17 KXL45405.1 - 0.054 13.0 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Ribosomal_L18 PF17135.4 KXL45406.1 - 3.3e-90 300.5 2.0 3.6e-90 300.4 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 KXL45406.1 - 0.00027 21.6 0.9 0.00044 20.9 0.0 1.9 2 1 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Tra_M PF05261.11 KXL45406.1 - 0.026 14.5 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 TraM protein, DNA-binding SHMT PF00464.19 KXL45407.1 - 9e-194 643.6 0.0 1.1e-193 643.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase MAD PF05557.13 KXL45409.1 - 1.2e-57 195.8 51.7 7.6e-57 193.1 51.8 2.1 1 1 1 2 2 2 1 Mitotic checkpoint protein HrpB7 PF09486.10 KXL45409.1 - 0.0049 17.3 11.6 0.0049 17.3 11.6 6.8 3 3 1 5 5 5 1 Bacterial type III secretion protein (HrpB7) DUF4156 PF13698.6 KXL45409.1 - 0.81 10.1 3.9 6.5 7.2 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4156) DUF3138 PF11336.8 KXL45409.1 - 4.3 5.8 15.9 0.19 10.3 5.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3138) DUF4051 PF13260.6 KXL45409.1 - 5.3 6.9 6.0 0.89 9.3 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) MAJIN PF15077.6 KXL45411.1 - 0.68 9.7 3.0 0.92 9.3 3.0 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein Arginase PF00491.21 KXL45412.1 - 2e-53 181.7 0.0 2.4e-53 181.5 0.0 1.0 1 0 0 1 1 1 1 Arginase family DUF2582 PF10771.9 KXL45412.1 - 0.035 14.3 0.0 3.2 8.0 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix domain (DUF2582) Sugar_tr PF00083.24 KXL45413.1 - 9.7e-97 324.6 16.4 1.2e-96 324.3 16.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL45413.1 - 2.8e-22 79.1 25.8 1.2e-21 77.1 21.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2104 PF09877.9 KXL45413.1 - 0.096 13.0 3.4 0.066 13.5 0.7 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2104) Skp1 PF01466.19 KXL45413.1 - 0.13 12.4 0.3 0.36 11.0 0.3 1.8 1 0 0 1 1 1 0 Skp1 family, dimerisation domain PIG-P PF08510.12 KXL45413.1 - 1.3 9.0 5.8 0.33 10.9 0.3 2.4 1 1 0 2 2 2 0 PIG-P DNA_primase_S PF01896.19 KXL45414.1 - 2.5e-61 206.8 0.1 3.9e-61 206.2 0.1 1.3 1 0 0 1 1 1 1 DNA primase small subunit DUF1917 PF08939.10 KXL45415.1 - 3e-54 184.7 0.0 4.3e-54 184.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) RNA_pol_Rpb2_5 PF04567.17 KXL45415.1 - 0.04 14.5 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 5 Amidohydro_1 PF01979.20 KXL45416.1 - 1.5e-25 90.3 0.0 2.9e-25 89.3 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXL45416.1 - 7.9e-14 52.0 0.1 3.4e-08 33.4 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.14 KXL45416.1 - 0.13 12.1 0.0 0.28 10.9 0.0 1.6 1 1 0 1 1 1 0 Amidohydrolase MSV199 PF10553.9 KXL45417.1 - 0.048 13.9 0.0 0.056 13.7 0.0 1.1 1 0 0 1 1 1 0 MSV199 domain Sulfatase PF00884.23 KXL45418.1 - 3.2e-65 220.5 0.0 4.7e-65 220.0 0.0 1.2 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 KXL45418.1 - 4.9e-22 78.1 5.0 2.5e-21 75.9 5.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 KXL45418.1 - 4.8e-06 26.4 3.6 3.1e-05 23.8 1.6 2.6 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KXL45418.1 - 0.073 11.7 0.1 0.12 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Fungal_trans PF04082.18 KXL45419.1 - 1.9e-06 27.1 0.1 3.1e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain RasGEF_N PF00618.20 KXL45420.1 - 1.1e-13 51.3 0.2 2.4e-13 50.2 0.2 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif 2-oxoacid_dh PF00198.23 KXL45420.1 - 0.16 11.4 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Auxin_repressed PF05564.12 KXL45420.1 - 3.3 8.4 7.7 0.4 11.4 1.2 2.4 2 0 0 2 2 2 0 Dormancy/auxin associated protein RasGEF PF00617.19 KXL45421.1 - 8.9e-47 159.6 0.2 1.2e-46 159.2 0.2 1.2 1 0 0 1 1 1 1 RasGEF domain APG9 PF04109.16 KXL45422.1 - 8.5e-178 592.3 12.2 1e-177 592.0 12.2 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 DUF3295 PF11702.8 KXL45423.1 - 1.2e-159 532.8 28.4 1.5e-159 532.6 28.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 KXL45423.1 - 5.2e-11 42.2 4.4 9.6e-11 41.3 4.4 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Sigma70_ner PF04546.13 KXL45423.1 - 3.4 7.5 6.7 29 4.5 0.0 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region ArAE_2_N PF10337.9 KXL45424.1 - 7.6e-48 163.7 6.6 7.6e-48 163.7 6.6 4.1 4 1 0 4 4 4 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 KXL45424.1 - 3.4e-16 59.5 13.6 3.4e-16 59.5 13.6 3.6 3 0 0 3 3 3 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 KXL45424.1 - 8.3e-10 38.9 0.0 2e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 SH3_1 PF00018.28 KXL45427.1 - 2.6e-05 23.7 0.0 7.5e-05 22.3 0.0 1.9 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXL45427.1 - 0.017 15.0 0.2 0.11 12.4 0.0 2.3 2 0 0 2 2 2 0 Variant SH3 domain CAF1A PF12253.8 KXL45427.1 - 1.9 8.7 9.1 11 6.3 0.1 3.5 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A MDM10 PF12519.8 KXL45428.1 - 5.1e-142 474.0 6.1 2.6e-127 425.5 3.7 2.0 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 KXL45428.1 - 8.5e-06 25.4 0.7 0.038 13.4 0.0 3.0 3 0 0 3 3 3 2 Eukaryotic porin Ribonuc_red_sm PF00268.21 KXL45429.1 - 1.2e-121 405.5 0.5 1.5e-121 405.1 0.5 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4680 PF15730.5 KXL45429.1 - 0.043 14.2 0.0 0.12 12.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4680) MAPEG PF01124.18 KXL45430.1 - 7e-22 77.7 0.4 7.8e-22 77.6 0.4 1.0 1 0 0 1 1 1 1 MAPEG family ADH_zinc_N PF00107.26 KXL45431.1 - 9.9e-11 41.7 0.0 2.1e-09 37.5 0.0 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXL45431.1 - 9.1e-06 26.8 0.0 2.2e-05 25.5 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXL45431.1 - 1.7e-05 24.7 0.0 0.013 15.4 0.0 2.6 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.19 KXL45431.1 - 1.7e-05 24.3 0.0 0.00076 18.9 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 KXL45431.1 - 9e-05 22.0 0.1 0.00024 20.6 0.1 1.7 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family ELFV_dehydrog PF00208.21 KXL45431.1 - 0.0034 17.1 0.0 0.0048 16.6 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase RmlD_sub_bind PF04321.17 KXL45431.1 - 0.0089 15.2 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain DapB_N PF01113.20 KXL45431.1 - 0.018 15.2 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.6 KXL45431.1 - 0.041 13.8 0.2 0.063 13.2 0.2 1.3 1 0 0 1 1 1 0 NAD(P)H-binding LDcluster4 PF18306.1 KXL45431.1 - 0.041 13.5 0.3 0.1 12.2 0.3 1.6 1 0 0 1 1 1 0 SLOG cluster4 family GDP_Man_Dehyd PF16363.5 KXL45431.1 - 0.23 10.8 0.0 0.38 10.1 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RNA_pol_Rpc4 PF05132.14 KXL45432.1 - 8.2e-33 113.9 0.0 8.2e-33 113.9 0.0 4.6 4 1 1 5 5 5 1 RNA polymerase III RPC4 ABC2_membrane PF01061.24 KXL45434.1 - 4.7e-12 45.8 19.8 5.8e-12 45.5 19.8 1.1 1 0 0 1 1 1 1 ABC-2 type transporter DUF973 PF06157.11 KXL45434.1 - 0.091 11.8 4.7 0.13 11.3 4.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF973) Transgly_assoc PF04226.13 KXL45435.1 - 0.082 13.2 4.7 0.13 12.5 4.7 1.3 1 0 0 1 1 1 0 Transglycosylase associated protein Rick_17kDa_Anti PF05433.15 KXL45435.1 - 0.13 12.1 11.4 0.24 11.3 11.4 1.3 1 0 0 1 1 1 0 Glycine zipper 2TM domain TraT PF05818.12 KXL45435.1 - 0.14 11.8 0.2 0.2 11.4 0.2 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein AMP-binding PF00501.28 KXL45436.1 - 8.7e-39 133.3 0.0 1.1e-38 132.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KXL45436.1 - 7.1e-12 45.1 2.6 9.2e-12 44.7 0.6 2.3 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KXL45436.1 - 0.0007 20.5 0.0 0.0025 18.8 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF1810 PF08837.11 KXL45436.1 - 0.044 13.6 0.0 0.083 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1810) DUF1772 PF08592.11 KXL45437.1 - 1.1e-15 58.1 0.7 1.3e-15 57.9 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) RyR PF02026.16 KXL45438.1 - 4.2e-10 39.7 0.0 1.6e-06 28.2 0.0 2.3 2 0 0 2 2 2 2 RyR domain DnaJ PF00226.31 KXL45440.1 - 4.7e-15 55.5 0.3 1.1e-14 54.2 0.3 1.7 1 0 0 1 1 1 1 DnaJ domain HET PF06985.11 KXL45440.1 - 1.7e-12 47.9 0.1 6e-12 46.1 0.1 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 KXL45442.1 - 1.1e-34 119.9 33.6 1.8e-34 119.2 33.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL45442.1 - 5.5e-10 38.7 8.3 5.5e-10 38.7 8.3 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter Imm3 PF14425.6 KXL45443.1 - 0.057 13.5 0.2 0.059 13.4 0.2 1.0 1 0 0 1 1 1 0 Immunity protein Imm3 Inositol_P PF00459.25 KXL45445.1 - 1.9e-50 171.9 0.2 7.4e-50 170.0 0.2 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family Peptidase_S78_2 PF14550.6 KXL45446.1 - 0.094 12.8 0.5 0.17 12.0 0.5 1.4 1 0 0 1 1 1 0 Putative phage serine protease XkdF ABC_tran PF00005.27 KXL45447.1 - 1.2e-49 168.4 0.2 1.7e-24 86.9 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KXL45447.1 - 1.3e-20 74.5 0.4 0.00011 22.1 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KXL45447.1 - 4.6e-17 62.1 56.1 4.4e-09 35.9 29.1 2.6 2 0 0 2 2 2 2 ABC-2 family transporter protein SMC_N PF02463.19 KXL45447.1 - 1.5e-08 34.3 2.2 0.0012 18.3 0.1 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXL45447.1 - 1.5e-06 27.9 1.4 0.02 14.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXL45447.1 - 2.9e-06 27.3 0.1 0.0052 16.7 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KXL45447.1 - 2.3e-05 25.0 2.6 0.13 12.7 0.5 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KXL45447.1 - 0.00027 20.7 1.9 0.38 10.4 0.0 2.9 2 1 1 3 3 3 2 AAA domain SRP54 PF00448.22 KXL45447.1 - 0.00028 20.6 0.4 0.14 11.8 0.4 2.7 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain DUF4162 PF13732.6 KXL45447.1 - 0.00035 21.2 0.1 0.035 14.8 0.0 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF4162) AAA_15 PF13175.6 KXL45447.1 - 0.0013 18.5 0.0 0.18 11.5 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain SbcCD_C PF13558.6 KXL45447.1 - 0.0014 18.8 0.5 10 6.4 0.0 4.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 KXL45447.1 - 0.0065 16.9 0.0 1.2 9.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 KXL45447.1 - 0.011 16.0 0.2 1 9.6 0.2 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KXL45447.1 - 0.048 13.2 0.5 11 5.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KXL45447.1 - 0.05 13.9 1.8 1.1 9.5 0.2 2.9 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KXL45447.1 - 0.12 12.7 0.5 3.3 8.0 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 KXL45447.1 - 0.15 11.6 0.2 7.6 6.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain RecA PF00154.21 KXL45447.1 - 0.18 11.2 0.5 11 5.4 0.0 2.7 3 0 0 3 3 3 0 recA bacterial DNA recombination protein AAA_24 PF13479.6 KXL45447.1 - 0.44 10.2 1.8 6.6 6.4 0.2 2.4 2 0 0 2 2 2 0 AAA domain TPR_8 PF13181.6 KXL45448.1 - 0.065 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXL45448.1 - 0.17 12.0 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Cation_efflux PF01545.21 KXL45449.1 - 1.1e-25 90.6 4.6 1.4e-25 90.2 4.6 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KXL45449.1 - 0.0063 16.6 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter GFO_IDH_MocA PF01408.22 KXL45450.1 - 5.9e-19 69.1 0.0 8.9e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXL45450.1 - 2e-07 31.0 0.0 1e-06 28.7 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KXL45450.1 - 0.05 14.3 0.0 0.082 13.6 0.0 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DUF2012 PF09430.10 KXL45451.1 - 1.9e-25 89.3 0.0 2.5e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) SOP4 PF17081.5 KXL45451.1 - 0.023 14.2 0.0 1.8 8.1 0.0 2.1 2 0 0 2 2 2 0 Suppressor of PMA 1-7 protein Mito_carr PF00153.27 KXL45452.1 - 7.7e-51 170.0 4.8 2.2e-16 59.5 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Abp2 PF09441.10 KXL45453.1 - 1.9e-83 278.7 0.0 4.3e-83 277.5 0.0 1.6 1 0 0 1 1 1 1 ARS binding protein 2 TPT PF03151.16 KXL45454.1 - 5.5e-53 180.2 10.1 6.6e-53 179.9 10.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KXL45454.1 - 2.3e-10 40.2 10.8 4.2e-10 39.3 10.8 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KXL45454.1 - 2e-07 31.3 25.7 8.6e-05 22.7 6.7 2.9 2 2 0 2 2 2 2 EamA-like transporter family Peptidase_S9 PF00326.21 KXL45455.1 - 1.8e-08 34.2 0.0 2.8e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KXL45455.1 - 0.15 11.8 0.0 2.2 8.0 0.0 2.5 2 1 0 3 3 3 0 Phospholipase/Carboxylesterase RHD3 PF05879.12 KXL45456.1 - 0 1011.9 0.0 0 1011.6 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 KXL45456.1 - 1e-07 31.5 0.1 1.8e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 KXL45456.1 - 1.5e-05 25.1 0.0 3.2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KXL45456.1 - 0.00028 20.9 0.0 0.0006 19.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KXL45456.1 - 0.013 15.7 0.2 0.1 12.8 0.0 2.6 2 1 1 3 3 3 0 AAA domain DUF2461 PF09365.10 KXL45456.1 - 0.035 14.0 0.1 0.4 10.6 0.1 2.4 1 1 1 2 2 2 0 Conserved hypothetical protein (DUF2461) PUF PF00806.19 KXL45457.1 - 4e-38 127.0 0.9 2.1e-06 27.1 0.0 8.9 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat RraB PF06877.11 KXL45457.1 - 0.00014 22.5 0.0 0.00051 20.7 0.0 1.9 1 0 0 1 1 1 1 Regulator of ribonuclease activity B Phage_lambda_P PF06992.11 KXL45457.1 - 0.067 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Replication protein P RasGEF PF00617.19 KXL45457.1 - 0.097 12.9 0.0 0.42 10.8 0.0 2.2 2 0 0 2 2 2 0 RasGEF domain Choline_transpo PF04515.12 KXL45458.1 - 6.2e-26 91.4 23.7 6.2e-26 91.4 23.7 3.0 1 1 1 2 2 2 1 Plasma-membrane choline transporter CLPTM1 PF05602.12 KXL45459.1 - 2.2e-153 511.3 0.1 2.6e-153 511.1 0.1 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF1772 PF08592.11 KXL45459.1 - 0.022 15.1 0.8 0.14 12.5 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) Thioredoxin PF00085.20 KXL45460.1 - 3.6e-07 30.1 0.0 5e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KXL45460.1 - 0.0041 17.6 0.0 0.022 15.2 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 KXL45460.1 - 0.062 13.0 0.0 0.088 12.5 0.0 1.2 1 0 0 1 1 1 0 Redoxin Thioredoxin_8 PF13905.6 KXL45460.1 - 0.12 12.8 0.0 14 6.1 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin-like DUF953 PF06110.11 KXL45460.1 - 0.16 11.6 0.2 16 5.2 0.1 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) BES1_N PF05687.13 KXL45464.1 - 4.7 7.6 11.1 5.6 7.3 10.1 1.7 1 1 1 2 2 2 0 BES1/BZR1 plant transcription factor, N-terminal Tubulin_3 PF14881.6 KXL45465.1 - 1.1e-68 230.5 0.0 1.6e-68 229.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 KXL45465.1 - 1e-39 135.5 0.1 3.1e-39 133.9 0.0 1.9 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 KXL45465.1 - 0.00015 22.0 0.0 0.46 10.7 0.0 2.5 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain SNO PF01174.19 KXL45468.1 - 2.7e-55 187.2 0.0 3.2e-46 157.6 0.0 2.1 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 KXL45468.1 - 3.9e-08 33.1 0.0 1.5e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 KXL45468.1 - 0.0014 18.4 0.0 0.002 18.0 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_S51 PF03575.17 KXL45468.1 - 0.0049 16.5 0.0 0.0077 15.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 GATase PF00117.28 KXL45468.1 - 0.042 13.6 0.0 7.6 6.3 0.0 2.2 2 0 0 2 2 2 0 Glutamine amidotransferase class-I RRM_1 PF00076.22 KXL45469.1 - 1.1e-15 57.1 0.0 1.7e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup88 PF10168.9 KXL45470.1 - 0.0023 15.9 3.7 2.2 6.0 1.7 3.3 3 1 0 3 3 3 3 Nuclear pore component WD40 PF00400.32 KXL45470.1 - 0.023 15.6 0.1 5.7 8.0 0.0 3.0 2 0 0 2 2 2 0 WD domain, G-beta repeat adh_short_C2 PF13561.6 KXL45471.1 - 3.4e-37 128.2 0.0 4.6e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL45471.1 - 2.7e-26 92.3 0.0 3.2e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL45471.1 - 6e-07 29.5 0.0 9.3e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KXL45471.1 - 0.0039 16.5 0.1 0.0093 15.3 0.0 1.6 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.8 KXL45471.1 - 0.035 13.9 0.4 0.085 12.6 0.4 1.7 1 1 1 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.21 KXL45471.1 - 0.054 12.9 0.0 0.099 12.1 0.0 1.4 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KXL45471.1 - 0.091 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KXL45471.1 - 0.11 13.0 0.0 0.2 12.1 0.0 1.5 2 0 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 KXL45471.1 - 0.19 11.6 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SNase PF00565.17 KXL45472.1 - 7e-75 248.4 0.9 1.1e-25 90.2 0.0 6.1 6 0 0 6 6 6 5 Staphylococcal nuclease homologue TUDOR PF00567.24 KXL45472.1 - 2.5e-20 72.7 0.0 8.2e-20 71.1 0.0 1.9 2 0 0 2 2 2 1 Tudor domain SMN PF06003.12 KXL45472.1 - 6.6e-05 22.3 0.0 0.00013 21.3 0.0 1.4 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) 7TMR-DISMED2 PF07696.11 KXL45472.1 - 0.0025 17.9 0.0 0.93 9.6 0.0 2.4 2 0 0 2 2 2 2 7TMR-DISM extracellular 2 2OG-FeII_Oxy_2 PF13532.6 KXL45473.1 - 3.9e-16 59.8 0.1 9.1e-16 58.6 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DDE_1 PF03184.19 KXL45474.1 - 2.8e-05 23.9 0.1 3.2e-05 23.7 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DASH_Dad3 PF08656.10 KXL45474.1 - 0.064 13.3 0.0 0.069 13.2 0.0 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad3 zf-C3H1 PF10650.9 KXL45476.1 - 3.4e-08 33.1 2.6 5.9e-08 32.3 2.6 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain SNAPc19 PF15497.6 KXL45476.1 - 0.58 10.7 4.2 1.7 9.2 0.6 3.4 2 0 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Myosin_head PF00063.21 KXL45477.1 - 5.7e-152 507.3 2.9 5.6e-151 504.0 0.0 2.8 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 KXL45477.1 - 1.3e-11 43.1 282.1 1.6e-09 36.2 118.3 7.3 2 2 0 2 2 2 2 Myosin tail Uso1_p115_C PF04871.13 KXL45477.1 - 0.0089 16.4 17.1 0.0089 16.4 17.1 16.6 5 3 9 14 14 14 2 Uso1 / p115 like vesicle tethering protein, C terminal region Exo_endo_phos PF03372.23 KXL45478.1 - 0.0057 16.2 0.0 0.026 14.1 0.0 2.1 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DUF2293 PF10056.9 KXL45479.1 - 1.4e-29 102.2 0.0 3.5e-29 100.9 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) SDA1 PF05285.12 KXL45479.1 - 0.074 12.5 3.7 0.13 11.6 3.7 1.4 1 0 0 1 1 1 0 SDA1 GLE1 PF07817.13 KXL45480.1 - 1.4e-38 132.5 0.0 2.3e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 GLE1-like protein DUF572 PF04502.13 KXL45480.1 - 2.9 7.4 27.9 4.4 6.8 27.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) RNB PF00773.19 KXL45481.1 - 8.7e-88 294.8 0.1 1.9e-87 293.6 0.1 1.6 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 KXL45481.1 - 2.3e-27 94.8 0.0 7.1e-27 93.2 0.0 1.9 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 KXL45481.1 - 2.3e-25 88.7 0.0 6.8e-25 87.2 0.0 1.8 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 KXL45481.1 - 8.1e-06 25.9 0.0 0.0043 17.2 0.0 2.9 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 KXL45481.1 - 0.00015 21.5 1.2 0.00065 19.4 0.0 2.3 2 0 0 2 2 2 1 Rrp44-like cold shock domain EMP24_GP25L PF01105.24 KXL45482.1 - 2.4e-51 174.3 0.2 2.8e-51 174.1 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD ArabFuran-catal PF09206.11 KXL45483.1 - 3e-135 450.6 12.1 3.4e-135 450.4 12.1 1.0 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic CBFB_NFYA PF02045.15 KXL45484.1 - 1.2e-27 96.3 4.7 1.2e-27 96.3 4.7 1.7 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B TFIIA PF03153.13 KXL45484.1 - 0.0049 16.9 20.8 0.0058 16.7 20.8 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Hus1 PF04005.12 KXL45484.1 - 0.13 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Hus1-like protein Ribosomal_L37 PF08561.10 KXL45486.1 - 2.6e-40 137.7 0.0 3.5e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 CCSAP PF15748.5 KXL45486.1 - 1 9.5 11.8 12 6.0 8.7 2.4 2 1 0 2 2 2 0 Centriole, cilia and spindle-associated DUF3446 PF11928.8 KXL45486.1 - 4.2 7.7 15.8 1 9.7 3.1 2.2 2 0 0 2 2 2 0 Early growth response N-terminal domain Aldo_ket_red PF00248.21 KXL45487.1 - 3e-47 161.2 0.0 3.7e-47 161.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_16 PF00722.21 KXL45488.1 - 7.2e-41 139.6 0.2 1.6e-40 138.5 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Tim17 PF02466.19 KXL45489.1 - 5e-13 49.4 1.2 1.1e-12 48.4 1.2 1.5 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family zf-H2C2_5 PF13909.6 KXL45492.1 - 0.26 11.1 9.8 6.9 6.5 0.8 4.2 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KXL45492.1 - 0.5 10.9 38.7 0.25 11.9 1.3 7.1 7 1 0 7 7 7 0 Zinc finger, C2H2 type Pro-kuma_activ PF09286.11 KXL45493.1 - 1.1e-49 168.4 0.1 2.2e-48 164.2 0.0 2.2 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KXL45493.1 - 1.2e-05 24.8 0.3 1.9e-05 24.1 0.3 1.2 1 0 0 1 1 1 1 Subtilase family Ribosomal_S8e PF01201.22 KXL45494.1 - 2.2e-47 160.6 1.1 4.1e-47 159.8 1.1 1.4 1 1 0 1 1 1 1 Ribosomal protein S8e PA26 PF04636.13 KXL45494.1 - 0.14 11.1 2.8 0.18 10.7 2.8 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) US30 PF17624.2 KXL45494.1 - 0.48 9.4 2.1 0.67 8.9 2.1 1.2 1 0 0 1 1 1 0 Family of unknown function Pannexin_like PF12534.8 KXL45494.1 - 1.5 7.9 6.2 2.1 7.4 6.2 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Ribosomal_L21p PF00829.21 KXL45495.1 - 3.8e-05 23.9 0.4 0.083 13.2 0.0 2.3 2 0 0 2 2 2 2 Ribosomal prokaryotic L21 protein PSDC PF12588.8 KXL45496.1 - 0.015 15.3 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Phophatidylserine decarboxylase Peptidase_S9 PF00326.21 KXL45498.1 - 3.7e-55 186.7 2.4 6.1e-55 186.0 2.4 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_N PF00930.21 KXL45498.1 - 8.6e-28 97.1 0.1 1.4e-27 96.4 0.1 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S15 PF02129.18 KXL45498.1 - 1.8e-06 27.8 4.1 1.7e-05 24.6 2.3 2.1 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 KXL45498.1 - 0.0026 18.4 0.0 1.2 9.7 0.1 2.4 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXL45498.1 - 0.0044 16.7 0.2 0.039 13.6 0.1 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 KXL45498.1 - 0.011 15.2 0.1 0.12 11.9 0.1 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KXL45498.1 - 0.02 14.7 0.1 4.2 7.1 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase ELMO_CED12 PF04727.13 KXL45499.1 - 7.9e-43 146.6 0.0 1.4e-42 145.8 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 KXL45499.1 - 9.7e-33 113.6 0.0 2.7e-32 112.1 0.0 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 KXL45499.1 - 6.4e-12 45.7 0.0 2.3e-11 43.9 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) DPPIV_N PF00930.21 KXL45500.1 - 3.6e-43 147.7 0.3 4.9e-43 147.2 0.3 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.12 KXL45500.1 - 0.19 11.7 3.8 13 5.9 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Pkinase PF00069.25 KXL45501.1 - 1.8e-47 161.9 0.0 2.5e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL45501.1 - 6.1e-16 58.5 0.0 1.3e-15 57.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KXL45501.1 - 9.2e-05 22.5 0.6 0.00047 20.2 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF4813 PF16072.5 KXL45501.1 - 0.0062 16.2 4.5 0.0091 15.7 4.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4813) Kinase-like PF14531.6 KXL45501.1 - 0.15 11.3 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 KXL45501.1 - 0.16 11.6 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.11 KXL45501.1 - 0.2 10.6 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase MFS_1 PF07690.16 KXL45503.1 - 2e-32 112.5 40.8 2e-32 112.5 40.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_2 PF00891.18 KXL45504.1 - 1.1e-18 67.3 0.0 1.9e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain TrmB PF01978.19 KXL45504.1 - 0.084 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Hydrolase_6 PF13344.6 KXL45505.1 - 1.1e-24 86.4 0.0 2.2e-24 85.5 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXL45505.1 - 3.9e-14 52.5 0.0 1.7e-13 50.4 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KXL45505.1 - 0.0019 18.5 0.0 3.4 7.9 0.0 3.2 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase T3SS_basalb_I PF17001.5 KXL45506.1 - 0.28 11.8 1.7 0.6 10.7 0.2 2.2 2 0 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI p450 PF00067.22 KXL45507.1 - 3.1e-36 125.1 0.0 7.2e-26 90.9 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Transp_cyt_pur PF02133.15 KXL45508.1 - 2.2e-150 501.3 40.4 2.5e-150 501.1 40.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Zn_clus PF00172.18 KXL45509.1 - 4.3e-08 33.1 7.2 6.6e-08 32.5 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IL2 PF00715.17 KXL45509.1 - 0.046 13.7 0.1 0.14 12.1 0.1 1.7 1 0 0 1 1 1 0 Interleukin 2 Anp1 PF03452.14 KXL45510.1 - 4.3e-110 367.3 0.0 5e-110 367.0 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 KXL45510.1 - 0.026 14.3 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 DSX_dimer PF08828.10 KXL45510.1 - 0.05 13.3 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Doublesex dimerisation domain DUF1996 PF09362.10 KXL45511.1 - 4.5e-80 269.0 0.5 6.7e-80 268.4 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 KXL45511.1 - 1.6e-18 66.7 10.5 3.7e-18 65.5 10.5 1.7 1 0 0 1 1 1 1 WSC domain Toxin_21 PF08091.11 KXL45511.1 - 0.13 12.2 5.1 0.39 10.7 5.1 1.8 1 0 0 1 1 1 0 Spider insecticidal peptide NETI PF14044.6 KXL45511.1 - 0.15 11.8 0.1 0.4 10.4 0.1 1.7 1 0 0 1 1 1 0 NETI protein FAD_binding_3 PF01494.19 KXL45512.1 - 1.1e-16 61.1 0.0 1.9e-07 30.7 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KXL45512.1 - 6e-07 29.4 0.8 0.0041 16.7 1.9 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXL45512.1 - 1.2e-06 28.0 0.5 1.6e-05 24.3 0.5 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXL45512.1 - 0.00024 20.1 0.4 0.0019 17.2 0.1 2.2 2 1 1 3 3 3 1 Tryptophan halogenase FAD_binding_2 PF00890.24 KXL45512.1 - 0.00034 19.8 1.3 0.00066 18.9 1.3 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXL45512.1 - 0.0021 18.3 0.8 0.0021 18.3 0.8 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXL45512.1 - 0.007 16.9 0.0 0.14 12.8 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXL45512.1 - 0.0094 14.7 2.2 0.14 10.9 1.6 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 KXL45512.1 - 0.022 14.0 0.2 0.04 13.2 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXL45512.1 - 0.026 13.6 0.5 0.085 11.9 0.0 2.0 2 1 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 KXL45512.1 - 0.028 13.5 0.1 0.042 12.9 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 KXL45512.1 - 0.075 12.3 0.6 0.12 11.7 0.6 1.3 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 KXL45512.1 - 0.18 11.1 0.6 0.43 9.8 0.6 1.8 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SE PF08491.10 KXL45512.1 - 0.19 10.7 0.0 0.45 9.5 0.0 1.5 2 0 0 2 2 2 0 Squalene epoxidase adh_short_C2 PF13561.6 KXL45513.1 - 6.3e-41 140.4 0.1 5.9e-40 137.3 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL45513.1 - 2.5e-37 128.3 0.7 6.3e-36 123.7 0.3 2.4 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KXL45513.1 - 2e-09 37.6 0.0 3.1e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXL45513.1 - 0.027 13.6 0.1 0.039 13.1 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 KXL45513.1 - 0.043 13.3 0.0 0.075 12.5 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family LDcluster4 PF18306.1 KXL45513.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 SLOG cluster4 family GDP_Man_Dehyd PF16363.5 KXL45513.1 - 0.19 11.1 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase zf-C2H2 PF00096.26 KXL45514.1 - 3.7e-07 30.2 16.1 0.00088 19.6 0.7 4.1 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXL45514.1 - 4.3e-06 27.1 13.0 0.018 15.8 0.8 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KXL45514.1 - 0.028 14.2 0.8 0.1 12.5 0.2 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-Di19 PF05605.12 KXL45514.1 - 0.062 13.6 8.5 0.21 11.9 4.6 3.0 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KXL45514.1 - 0.25 11.8 4.6 0.95 9.9 0.5 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 KXL45514.1 - 0.47 11.1 3.4 12 6.6 0.1 3.2 2 1 1 3 3 3 0 FOXP coiled-coil domain C1_4 PF07975.12 KXL45514.1 - 2.4 8.4 5.3 2.2 8.6 0.2 3.1 3 0 0 3 3 3 0 TFIIH C1-like domain zf-C2H2_6 PF13912.6 KXL45514.1 - 4.9 7.3 10.0 3.8 7.6 0.2 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger Arf PF00025.21 KXL45515.1 - 6.6e-06 25.7 0.1 1.1e-05 25.0 0.1 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KXL45515.1 - 0.076 12.4 0.1 0.098 12.1 0.1 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PTPA PF03095.15 KXL45516.1 - 2.4e-107 358.9 0.0 2.8e-107 358.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF676 PF05057.14 KXL45517.1 - 2.1e-45 154.9 0.0 3.3e-45 154.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 KXL45517.1 - 0.00031 20.6 0.0 0.00048 20.0 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 KXL45517.1 - 0.0061 16.3 0.1 0.012 15.4 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KXL45517.1 - 0.015 15.9 0.1 0.13 12.8 0.0 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 KXL45517.1 - 0.077 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DLH PF01738.18 KXL45517.1 - 0.16 11.5 0.0 1 8.9 0.0 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family YqzE PF14038.6 KXL45517.1 - 0.17 11.9 0.1 0.33 11.0 0.1 1.4 1 0 0 1 1 1 0 YqzE-like protein MFS_1 PF07690.16 KXL45519.1 - 1.3e-32 113.1 10.4 9.9e-19 67.5 3.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXL45519.1 - 2.6e-05 22.7 2.5 0.052 11.8 0.2 2.8 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 KXL45519.1 - 2.7e-05 22.9 17.9 0.00034 19.3 5.6 2.7 2 1 1 3 3 3 2 MFS/sugar transport protein Sugar_tr PF00083.24 KXL45519.1 - 7.9e-05 21.7 10.4 0.004 16.1 3.7 3.3 2 1 0 3 3 3 3 Sugar (and other) transporter MFS_1_like PF12832.7 KXL45519.1 - 0.0024 16.8 3.2 0.0024 16.8 3.2 2.6 2 1 0 2 2 2 1 MFS_1 like family FAM176 PF14851.6 KXL45519.1 - 0.047 13.4 1.9 1.5 8.5 0.0 2.6 3 0 0 3 3 3 0 FAM176 family DUF1645 PF07816.11 KXL45519.1 - 0.07 13.7 0.1 0.12 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) DUF5345 PF17280.2 KXL45519.1 - 0.19 11.7 0.4 0.55 10.3 0.4 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5345) NAD_binding_2 PF03446.15 KXL45520.1 - 0.0015 18.7 0.0 0.03 14.5 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXL45520.1 - 0.054 13.7 0.1 0.089 13.0 0.1 1.4 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DUF4588 PF15251.6 KXL45521.1 - 0.093 12.5 0.2 0.45 10.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4588) PrsW-protease PF13367.6 KXL45522.1 - 1.6e-14 53.8 0.0 2.6e-14 53.1 0.0 1.5 1 1 0 1 1 1 1 PrsW family intramembrane metalloprotease YhfC PF10086.9 KXL45522.1 - 0.066 12.6 0.4 0.42 9.9 0.1 2.3 1 1 1 2 2 2 0 YhfC intramembrane metalloprotease RNA_pol_3_Rpc31 PF11705.8 KXL45523.1 - 8.3e-18 65.5 36.7 4.2e-16 59.9 36.7 2.6 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Pox_Ag35 PF03286.14 KXL45523.1 - 2.1 8.1 8.5 5.4 6.8 8.5 1.7 1 1 0 1 1 1 0 Pox virus Ag35 surface protein Cyclin_N PF00134.23 KXL45525.1 - 5.6e-05 22.9 0.0 0.011 15.5 0.0 2.4 2 1 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.19 KXL45525.1 - 0.05 13.7 0.0 0.25 11.4 0.0 2.2 3 0 0 3 3 3 0 Transcription factor TFIIB repeat CN_hydrolase PF00795.22 KXL45526.1 - 3.3e-32 111.8 0.0 4.6e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Paf67 PF10255.9 KXL45527.1 - 7.7e-155 515.9 0.0 8.9e-155 515.6 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 KXL45527.1 - 0.0025 17.8 0.1 0.015 15.3 0.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXL45527.1 - 0.073 12.9 0.0 0.37 10.7 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L50 PF10501.9 KXL45528.1 - 1.2e-13 51.1 0.3 3.5e-13 49.7 0.0 1.9 2 0 0 2 2 2 1 Ribosomal subunit 39S Pectinesterase PF01095.19 KXL45530.1 - 4e-25 88.1 0.3 1.6e-20 73.1 0.1 2.1 2 0 0 2 2 2 2 Pectinesterase zinc_ribbon_10 PF10058.9 KXL45531.1 - 0.21 11.3 0.2 0.39 10.5 0.2 1.5 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Fe-S_biosyn PF01521.20 KXL45532.1 - 7.4e-12 45.5 0.0 1.7e-11 44.3 0.0 1.6 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis PGM_PMM_I PF02878.16 KXL45533.1 - 1.2e-32 112.5 0.0 1.8e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KXL45533.1 - 6.1e-26 90.9 0.0 1.1e-25 90.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KXL45533.1 - 1.1e-15 58.2 0.1 2.6e-15 56.9 0.1 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KXL45533.1 - 2.4e-08 34.0 0.0 5.6e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain ATG11 PF10377.9 KXL45534.1 - 1.6e-39 134.9 0.1 1.6e-39 134.9 0.1 3.8 5 0 0 5 5 5 1 Autophagy-related protein 11 APG17 PF04108.12 KXL45534.1 - 1.2e-05 24.7 21.0 2.1e-05 23.8 5.2 6.0 3 2 2 5 5 5 2 Autophagy protein Apg17 KicB PF03882.14 KXL45534.1 - 0.015 15.5 2.0 0.034 14.4 0.3 2.5 2 0 0 2 2 2 0 MukF winged-helix domain ATG2_CAD PF13329.6 KXL45534.1 - 0.13 12.0 0.8 0.39 10.4 0.0 2.3 2 0 0 2 2 2 0 Autophagy-related protein 2 CAD motif DUF4635 PF15466.6 KXL45534.1 - 0.24 10.9 5.4 14 5.2 0.0 4.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4635) FAD_binding_3 PF01494.19 KXL45535.1 - 3.7e-21 75.8 0.1 6.7e-21 74.9 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXL45535.1 - 0.00022 20.9 0.2 0.13 11.8 0.0 2.9 1 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXL45535.1 - 0.00059 19.2 0.3 0.13 11.5 0.1 2.4 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXL45535.1 - 0.0018 18.8 0.0 0.45 11.1 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXL45535.1 - 0.0084 16.1 0.1 0.21 11.6 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KXL45535.1 - 0.095 11.7 0.2 0.35 9.9 0.0 1.9 2 1 0 2 2 2 0 Lycopene cyclase protein Glyco_hydro_3_C PF01915.22 KXL45536.1 - 1.1e-43 149.6 0.0 1.6e-43 149.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXL45536.1 - 6.5e-25 88.2 0.0 1.4e-24 87.0 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain MFS_1 PF07690.16 KXL45537.1 - 8.3e-38 130.2 33.4 8.3e-38 130.2 33.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL45537.1 - 1.2e-17 64.0 8.8 1.2e-17 64.0 8.8 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXL45537.1 - 5.1e-05 21.9 2.6 5.1e-05 21.9 2.6 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Clc-like PF07062.12 KXL45537.1 - 1.7 8.0 5.3 1 8.8 0.1 2.8 3 1 0 3 3 3 0 Clc-like Prefoldin_2 PF01920.20 KXL45538.1 - 6.6e-25 87.1 4.6 1e-24 86.5 4.6 1.3 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 KXL45538.1 - 0.0027 17.6 0.4 0.0027 17.6 0.4 2.2 1 1 1 2 2 2 1 Prefoldin subunit Rbsn PF11464.8 KXL45538.1 - 0.0043 16.7 2.7 0.0043 16.7 2.7 2.0 2 1 0 2 2 2 1 Rabenosyn Rab binding domain DUF4854 PF16146.5 KXL45538.1 - 0.052 13.9 1.4 0.084 13.2 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4854) NPV_P10 PF05531.12 KXL45538.1 - 0.066 13.7 2.2 0.35 11.4 0.3 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein CENP-H PF05837.12 KXL45538.1 - 0.15 12.5 0.7 0.15 12.5 0.7 2.4 2 1 0 2 2 2 0 Centromere protein H (CENP-H) DUF1664 PF07889.12 KXL45538.1 - 0.23 11.5 3.2 0.4 10.7 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) EMP24_GP25L PF01105.24 KXL45538.1 - 0.37 10.7 6.2 0.65 9.9 6.2 1.6 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD YabA PF06156.13 KXL45538.1 - 0.53 11.0 0.2 0.53 11.0 0.2 2.2 2 0 0 2 2 2 0 Initiation control protein YabA Tektin PF03148.14 KXL45538.1 - 0.81 8.4 14.9 0.081 11.7 2.9 2.1 1 1 1 2 2 2 0 Tektin family GAS PF13851.6 KXL45538.1 - 0.87 8.9 13.6 0.17 11.3 0.3 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding FlaC_arch PF05377.11 KXL45538.1 - 1 9.8 9.2 0.18 12.2 1.3 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) 5_nucleotid PF05761.14 KXL45538.1 - 1.2 8.0 5.2 1.8 7.4 5.2 1.4 1 1 0 1 1 1 0 5' nucleotidase family PI3K_P85_iSH2 PF16454.5 KXL45538.1 - 4.6 6.8 15.8 1.3e+02 2.0 15.8 2.0 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain V_ATPase_I PF01496.19 KXL45538.1 - 5.2 4.9 6.1 7.8 4.3 6.1 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_1 PF00170.21 KXL45538.1 - 7 6.8 14.7 0.45 10.7 3.1 2.3 2 0 0 2 2 2 0 bZIP transcription factor JIP_LZII PF16471.5 KXL45538.1 - 7.5 6.8 17.0 5.1 7.3 3.2 2.5 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II Seryl_tRNA_N PF02403.22 KXL45538.1 - 8.5 6.7 13.2 1.8 8.8 0.6 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain AA_permease_2 PF13520.6 KXL45539.1 - 5.7e-52 177.0 53.7 6.7e-51 173.4 53.7 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXL45539.1 - 1e-07 31.0 40.0 2e-06 26.7 40.0 2.1 1 1 0 1 1 1 1 Amino acid permease VIT1 PF01988.19 KXL45539.1 - 0.0022 17.9 0.3 0.0022 17.9 0.3 2.0 2 0 0 2 2 2 1 VIT family Alpha-amylase PF00128.24 KXL45540.1 - 4e-22 79.2 0.0 1.3e-19 71.0 0.0 2.2 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 KXL45540.1 - 0.043 12.0 0.2 11 4.1 0.1 3.0 3 0 0 3 3 3 0 Glycosyl hydrolase family 70 Chorismate_synt PF01264.21 KXL45540.1 - 0.1 11.3 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Chorismate synthase Mito_carr PF00153.27 KXL45541.1 - 3.7e-44 148.6 7.8 1.3e-16 60.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CaKB PF03185.15 KXL45542.1 - 0.076 12.7 0.0 0.092 12.4 0.0 1.1 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit DUF2347 PF09804.9 KXL45543.1 - 5.8e-87 291.9 0.0 8e-87 291.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 KXL45543.1 - 5.6e-39 134.4 7.1 7.2e-21 75.2 2.5 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4484) SPA PF08616.10 KXL45543.1 - 0.00013 21.9 0.0 0.00023 21.1 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 KXL45543.1 - 0.0063 15.2 0.0 0.41 9.3 0.0 2.5 2 1 1 3 3 3 2 Transport protein Avl9 SDA1 PF05285.12 KXL45544.1 - 2.5e-90 303.4 36.3 3.7e-90 302.8 29.3 2.1 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 KXL45544.1 - 7.2e-23 80.7 0.0 2e-22 79.2 0.0 1.9 1 0 0 1 1 1 1 NUC130/3NT domain Ctr PF04145.15 KXL45545.1 - 8.9e-37 127.0 0.1 1.1e-36 126.7 0.1 1.0 1 0 0 1 1 1 1 Ctr copper transporter family DUF1011 PF06237.12 KXL45545.1 - 0.3 11.5 4.5 0.14 12.5 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1011) Glyco_hydro_12 PF01670.16 KXL45546.1 - 2.1e-41 142.3 11.1 2.5e-41 142.0 11.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 PAP2 PF01569.21 KXL45547.1 - 2.9e-23 82.2 5.8 5.5e-23 81.2 5.8 1.4 1 0 0 1 1 1 1 PAP2 superfamily DUF2627 PF11118.8 KXL45547.1 - 1.4 9.5 5.4 7.9 7.1 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2627) CCB1 PF12046.8 KXL45547.1 - 1.9 7.8 5.2 9.1 5.6 0.4 2.5 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B CENP-X PF09415.10 KXL45548.1 - 4.7e-18 65.3 0.4 1.6e-17 63.6 0.0 1.9 2 0 0 2 2 2 1 CENP-S associating Centromere protein X TFIIF_alpha PF05793.12 KXL45548.1 - 0.009 14.7 6.5 0.012 14.2 6.5 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RXT2_N PF08595.11 KXL45548.1 - 0.025 14.6 0.6 0.035 14.1 0.6 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Nucleo_P87 PF07267.11 KXL45548.1 - 0.05 12.5 3.9 0.063 12.1 3.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 GP67 PF17634.2 KXL45548.1 - 0.11 13.0 8.9 0.056 13.9 5.9 1.8 2 0 0 2 2 2 0 Gene product 67 Sporozoite_P67 PF05642.11 KXL45548.1 - 0.11 10.5 1.1 0.14 10.3 1.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM176 PF14851.6 KXL45548.1 - 0.12 12.0 2.2 0.19 11.4 2.2 1.3 1 0 0 1 1 1 0 FAM176 family DUF4611 PF15387.6 KXL45548.1 - 0.14 12.4 4.8 0.28 11.4 4.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) PBP1_TM PF14812.6 KXL45548.1 - 0.16 12.3 6.4 0.33 11.3 6.4 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LAT PF15234.6 KXL45548.1 - 0.22 11.2 15.7 0.024 14.4 11.5 1.4 1 1 0 1 1 1 0 Linker for activation of T-cells Astro_capsid_p PF12226.8 KXL45548.1 - 0.22 10.6 3.2 0.27 10.3 3.2 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Myc_N PF01056.18 KXL45548.1 - 0.33 10.8 7.3 0.059 13.3 3.9 1.4 1 1 0 1 1 1 0 Myc amino-terminal region CENP-B_dimeris PF09026.10 KXL45548.1 - 1.2 9.5 10.6 2.6 8.5 10.0 1.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain NOA36 PF06524.12 KXL45548.1 - 2.5 7.4 6.8 3.3 6.9 6.8 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KXL45548.1 - 6.7 4.7 8.1 8.7 4.3 8.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi ELO PF01151.18 KXL45549.1 - 1.2e-76 257.6 0.7 1.4e-76 257.3 0.7 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF334 PF03904.13 KXL45549.1 - 0.11 12.1 0.7 0.21 11.1 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF334) MEDS PF14417.6 KXL45549.1 - 0.11 12.3 0.6 0.25 11.1 0.6 1.6 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain MDM31_MDM32 PF08118.11 KXL45549.1 - 1.1 7.8 2.9 0.39 9.3 0.0 1.6 2 0 0 2 2 2 0 Yeast mitochondrial distribution and morphology (MDM) proteins Haem_degrading PF03928.14 KXL45550.1 - 1.5e-35 121.8 0.1 1.8e-35 121.5 0.1 1.1 1 0 0 1 1 1 1 Haem-degrading DUF348 PF03990.14 KXL45550.1 - 0.052 13.3 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 G5-linked-Ubiquitin-like domain VWA PF00092.28 KXL45551.1 - 8e-08 32.7 0.0 1.5e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KXL45551.1 - 5.1e-05 23.9 0.0 9.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain FTR1 PF03239.14 KXL45553.1 - 9.7e-88 294.3 9.1 1.1e-87 294.1 9.1 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Ctr PF04145.15 KXL45553.1 - 0.041 14.5 0.1 0.13 12.9 0.1 1.9 1 0 0 1 1 1 0 Ctr copper transporter family LptF_LptG PF03739.14 KXL45553.1 - 0.45 9.3 6.0 0.2 10.4 3.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG YitT_membrane PF02588.15 KXL45553.1 - 0.49 9.7 9.0 2.9 7.2 0.8 2.8 2 1 1 3 3 3 0 Uncharacterised 5xTM membrane BCR, YitT family COG1284 Cu-oxidase_2 PF07731.14 KXL45555.1 - 1.4e-45 154.4 3.6 8.8e-41 138.9 0.6 3.2 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KXL45555.1 - 1.6e-38 132.3 0.5 5.7e-34 117.5 0.1 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXL45555.1 - 3.9e-38 130.1 2.3 3.2e-34 117.5 0.1 3.1 4 0 0 4 4 4 2 Multicopper oxidase OMPdecase PF00215.24 KXL45556.1 - 8.1e-76 254.5 0.0 9.7e-76 254.3 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family BetaGal_dom3 PF13363.6 KXL45556.1 - 0.01 15.4 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 Mcm10 PF09332.11 KXL45556.1 - 0.052 13.0 0.3 0.074 12.5 0.3 1.1 1 0 0 1 1 1 0 Mcm10 replication factor Cue1_U7BR PF18499.1 KXL45556.1 - 0.056 13.5 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Ubc7p-binding region of Cue1 Pinin_SDK_N PF04697.13 KXL45556.1 - 2.1 9.0 7.9 0.14 12.8 2.2 1.9 2 0 0 2 2 2 0 pinin/SDK conserved region DUF3357 PF11837.8 KXL45560.1 - 0.019 15.4 0.0 0.055 13.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DUF997 PF06196.12 KXL45560.1 - 0.28 11.2 0.9 0.5 10.4 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF997) hEGF PF12661.7 KXL45560.1 - 8.4 7.2 9.8 4.5 8.1 6.3 2.4 1 1 1 2 2 2 0 Human growth factor-like EGF Methyltrn_RNA_3 PF02598.17 KXL45561.1 - 4.7e-103 344.6 0.0 5.8e-103 344.3 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase bZIP_1 PF00170.21 KXL45563.1 - 5.5e-07 29.6 12.6 1.2e-06 28.5 12.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.10 KXL45563.1 - 2e-06 27.8 0.2 2e-06 27.8 0.2 2.4 1 1 1 2 2 2 1 Transcription factor PAP1 SHE3 PF17078.5 KXL45563.1 - 0.0064 16.2 4.8 0.0089 15.8 4.8 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 bZIP_Maf PF03131.17 KXL45563.1 - 0.042 14.4 11.7 0.072 13.6 11.7 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor Glutaredoxin2_C PF04399.13 KXL45563.1 - 0.18 11.7 1.1 0.3 10.9 1.1 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain bZIP_2 PF07716.15 KXL45563.1 - 0.49 10.5 14.3 0.6 10.2 12.4 2.0 1 1 1 2 2 2 0 Basic region leucine zipper ADIP PF11559.8 KXL45563.1 - 0.85 9.7 10.3 1.3 9.1 10.3 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding GvpL_GvpF PF06386.11 KXL45563.1 - 1.1 9.1 4.8 1.7 8.5 4.8 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF FAM104 PF15434.6 KXL45563.1 - 8.6 7.0 8.8 42 4.8 0.2 2.4 1 1 0 2 2 2 0 Family 104 PH_14 PF17787.1 KXL45564.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 PH domain Adaptin_N PF01602.20 KXL45565.1 - 1.7e-117 393.1 1.2 2.3e-117 392.8 1.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KXL45565.1 - 6.3e-56 188.7 1.8 1.5e-55 187.5 1.8 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KXL45565.1 - 6.7e-33 113.3 0.1 1.9e-32 111.8 0.1 1.9 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KXL45565.1 - 6.4e-21 74.5 2.3 4.9e-13 49.3 0.1 5.9 2 2 5 7 7 7 3 HEAT repeats Cnd1 PF12717.7 KXL45565.1 - 8.7e-10 38.9 12.5 0.019 15.0 0.2 5.2 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KXL45565.1 - 0.00033 20.7 6.2 0.24 11.8 0.2 6.0 5 0 0 5 5 5 1 HEAT repeat HEAT_PBS PF03130.16 KXL45565.1 - 0.0018 18.8 0.4 1.9 9.4 0.1 4.4 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 KXL45565.1 - 0.011 16.2 2.5 0.094 13.3 0.8 2.9 2 0 0 2 2 2 0 HEAT-like repeat Phosducin PF02114.16 KXL45566.1 - 7.7e-13 48.0 1.2 9.9e-13 47.6 1.1 1.3 1 1 0 1 1 1 1 Phosducin Lge1 PF11488.8 KXL45567.1 - 0.066 13.4 2.2 0.1 12.8 2.2 1.3 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 LIP PF03583.14 KXL45568.1 - 2e-61 207.8 0.4 2.9e-61 207.3 0.4 1.1 1 0 0 1 1 1 1 Secretory lipase Plectin PF00681.20 KXL45568.1 - 0.021 14.7 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 Plectin repeat Fungal_trans PF04082.18 KXL45569.1 - 1.8e-16 60.0 0.0 3e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL45569.1 - 2.2e-05 24.5 8.4 4.3e-05 23.6 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CN_hydrolase PF00795.22 KXL45570.1 - 8.6e-07 28.5 0.0 8.8e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CN_hydrolase PF00795.22 KXL45571.1 - 6.1e-22 78.2 0.0 1.1e-21 77.3 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Asp_Glu_race PF01177.22 KXL45571.1 - 2e-09 37.6 0.0 3.2e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase CAP59_mtransfer PF11735.8 KXL45573.1 - 1.8e-85 286.5 0.0 2.3e-85 286.2 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 HTH_19 PF12844.7 KXL45573.1 - 0.12 12.4 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain SET PF00856.28 KXL45574.1 - 0.0043 17.5 0.0 0.0051 17.2 0.0 1.2 1 0 0 1 1 1 1 SET domain DUF2256 PF10013.9 KXL45574.1 - 3.2 8.0 7.1 0.22 11.6 0.9 2.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) MoaE PF02391.17 KXL45575.1 - 1.4e-37 128.5 0.0 1.7e-37 128.2 0.0 1.1 1 0 0 1 1 1 1 MoaE protein zf-CCHC PF00098.23 KXL45576.1 - 0.15 12.2 2.6 0.33 11.1 2.6 1.6 1 0 0 1 1 1 0 Zinc knuckle RRM_1 PF00076.22 KXL45577.1 - 0.0039 17.0 0.0 0.0098 15.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Septin PF00735.18 KXL45578.1 - 2.3e-35 122.3 0.0 1.4e-11 44.2 0.0 3.1 3 0 0 3 3 3 3 Septin MMR_HSR1 PF01926.23 KXL45578.1 - 1.8e-05 24.8 0.0 5.2e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 KXL45578.1 - 0.0001 22.5 0.0 0.00027 21.1 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Spem1 PF15670.5 KXL45578.1 - 0.0002 21.0 0.7 0.00089 18.9 0.0 2.3 2 1 0 2 2 2 1 Spermatid maturation protein 1 FtsK_SpoIIIE PF01580.18 KXL45578.1 - 0.00024 20.5 0.0 0.00045 19.7 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family Dynamin_N PF00350.23 KXL45578.1 - 0.015 15.4 0.4 0.065 13.3 0.1 2.2 2 2 1 3 3 3 0 Dynamin family G-alpha PF00503.20 KXL45578.1 - 0.03 13.5 0.0 0.043 13.0 0.0 1.5 1 1 0 1 1 1 0 G-protein alpha subunit Ras PF00071.22 KXL45578.1 - 0.032 13.8 0.0 0.078 12.6 0.0 1.7 1 1 0 1 1 1 0 Ras family AAA_14 PF13173.6 KXL45578.1 - 0.089 12.8 0.0 0.7 9.9 0.0 2.3 2 1 1 3 3 3 0 AAA domain GcnA_N PF18229.1 KXL45578.1 - 0.097 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 N-acetyl-beta-D-glucosaminidase N-terminal domain AAA_16 PF13191.6 KXL45578.1 - 0.11 12.9 0.0 0.28 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain IIGP PF05049.13 KXL45578.1 - 0.12 11.4 0.0 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) SRPRB PF09439.10 KXL45578.1 - 0.13 11.7 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit BUD22 PF09073.10 KXL45578.1 - 0.6 9.4 7.6 0.88 8.8 7.6 1.3 1 1 0 1 1 1 0 BUD22 DUF2076 PF09849.9 KXL45579.1 - 9.6e-09 35.7 12.5 1.3e-08 35.3 12.5 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 KXL45579.1 - 8.4e-05 22.6 1.4 0.0002 21.4 1.5 1.6 1 1 1 2 2 2 2 CHCH domain CX9C PF16860.5 KXL45579.1 - 0.0013 18.7 1.1 0.0021 18.0 1.1 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Romo1 PF10247.9 KXL45579.1 - 0.014 15.8 0.1 0.024 15.0 0.1 1.4 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 START PF01852.19 KXL45579.1 - 0.15 11.5 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 START domain Ras PF00071.22 KXL45580.1 - 5.1e-55 185.5 0.0 5.9e-55 185.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXL45580.1 - 3.6e-21 75.6 0.0 5.5e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXL45580.1 - 7.7e-08 32.0 0.0 9.1e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXL45580.1 - 0.0017 17.9 0.0 0.004 16.7 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Sas10_Utp3 PF04000.15 KXL45581.1 - 4.8e-15 56.0 0.2 7.5e-15 55.3 0.2 1.3 1 0 0 1 1 1 1 Sas10/Utp3/C1D family LIAS_N PF16881.5 KXL45582.1 - 1.8e-24 86.2 0.0 3.8e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KXL45582.1 - 3.9e-14 53.4 0.0 5.9e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily UPF0139 PF03669.13 KXL45583.1 - 1.6e-07 31.1 0.1 2e-07 30.8 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) DUF308 PF03729.13 KXL45583.1 - 0.018 15.4 0.6 0.024 15.0 0.6 1.1 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) Med12 PF09497.10 KXL45584.1 - 2.6e-26 91.7 0.1 5.3e-26 90.7 0.1 1.6 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 MBA1 PF07961.11 KXL45585.1 - 6.9e-10 38.4 0.1 1.2e-09 37.6 0.1 1.4 1 0 0 1 1 1 1 MBA1-like protein dsDNA_bind PF01984.20 KXL45586.1 - 1.1e-37 128.7 11.6 1.3e-37 128.4 11.6 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain PAPS_reduct PF01507.19 KXL45587.1 - 1.4e-43 148.9 0.0 2e-43 148.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Troponin PF00992.20 KXL45587.1 - 0.14 12.4 1.7 0.39 11.0 0.1 2.1 2 0 0 2 2 2 0 Troponin ATP-sulfurylase PF01747.17 KXL45588.1 - 3.6e-87 291.3 0.0 5.3e-87 290.7 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 KXL45588.1 - 2.1e-56 190.2 0.0 3.1e-56 189.6 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 KXL45588.1 - 2.8e-54 183.1 0.0 4.9e-54 182.3 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain SUI1 PF01253.22 KXL45589.1 - 1.8e-27 95.7 3.6 2.6e-27 95.1 3.6 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF2201_N PF13203.6 KXL45590.1 - 0.17 11.4 8.5 0.47 10.0 8.5 1.7 1 0 0 1 1 1 0 Putative metallopeptidase domain Ribosomal_S14 PF00253.21 KXL45591.1 - 1.5e-23 82.3 4.8 2.4e-23 81.7 2.5 2.0 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e Sel1 PF08238.12 KXL45591.1 - 0.52 11.1 1.9 3.9 8.3 0.0 2.7 3 0 0 3 3 3 0 Sel1 repeat Calpain_u2 PF16648.5 KXL45592.1 - 0.098 13.1 0.8 0.24 11.9 0.1 1.9 2 0 0 2 2 2 0 Unstructured region on Calpain-3 DUF4551 PF15087.6 KXL45592.1 - 0.21 10.4 1.2 0.28 10.0 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Coq4 PF05019.13 KXL45593.1 - 7.9e-88 293.5 0.0 9.8e-88 293.2 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 ApbA_C PF08546.11 KXL45594.1 - 9.5e-31 106.6 1.0 1.6e-30 105.9 1.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KXL45594.1 - 2.6e-24 85.6 0.0 8.4e-17 61.2 0.0 2.4 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA Cnn_1N PF07989.11 KXL45595.1 - 0.064 13.4 0.9 0.12 12.5 0.9 1.4 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Prefoldin_3 PF13758.6 KXL45596.1 - 0.034 14.2 4.6 0.061 13.4 0.4 2.6 2 1 0 2 2 2 0 Prefoldin subunit APG6_N PF17675.1 KXL45596.1 - 0.67 10.5 16.3 1.2 9.7 6.8 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region FAA_hydro_N_2 PF18288.1 KXL45596.1 - 0.71 10.3 3.1 0.37 11.3 0.5 2.0 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 YabA PF06156.13 KXL45596.1 - 5.2 7.8 8.3 9.5 6.9 4.1 2.6 2 1 0 2 2 2 0 Initiation control protein YabA TP_methylase PF00590.20 KXL45597.1 - 4.9e-50 170.4 0.2 1e-49 169.4 0.2 1.6 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 KXL45597.1 - 1.4e-12 47.9 0.0 3.4e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KXL45597.1 - 4.6e-11 42.2 0.0 4.9e-08 32.5 0.0 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KXL45597.1 - 6.9e-11 41.4 0.2 2e-10 40.0 0.2 1.9 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Rogdi_lz PF10259.9 KXL45598.1 - 1.6e-83 280.3 0.0 1.8e-83 280.1 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein SUR7 PF06687.12 KXL45599.1 - 5.6e-32 111.1 15.1 6.5e-32 110.9 15.1 1.0 1 0 0 1 1 1 1 SUR7/PalI family Amastin PF07344.11 KXL45599.1 - 0.0012 18.8 12.6 0.0012 18.8 12.6 1.9 2 0 0 2 2 2 1 Amastin surface glycoprotein Clc-like PF07062.12 KXL45599.1 - 0.0044 16.5 3.1 0.0044 16.5 3.1 1.5 2 0 0 2 2 2 1 Clc-like DUF373 PF04123.13 KXL45599.1 - 0.43 10.0 5.5 0.098 12.1 2.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF373) DUF4231 PF14015.6 KXL45599.1 - 1.9 9.0 6.7 1.1 9.7 3.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF805 PF05656.14 KXL45599.1 - 5 7.6 9.6 1.1 9.7 5.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Acetyltransf_1 PF00583.25 KXL45600.1 - 5.8e-07 29.8 0.0 6.9e-07 29.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXL45600.1 - 3.3e-06 27.1 0.0 5.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXL45600.1 - 6e-05 23.4 0.0 9.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXL45600.1 - 0.053 13.6 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AA_permease_2 PF13520.6 KXL45601.1 - 1.2e-39 136.4 53.6 1.5e-39 136.1 53.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXL45601.1 - 1.4e-15 56.9 45.0 1.9e-15 56.5 45.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3043 PF11241.8 KXL45601.1 - 7.4 6.6 6.0 9.7 6.2 1.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Fanconi_C PF02106.15 KXL45602.1 - 0.044 12.5 0.0 0.048 12.4 0.0 1.1 1 0 0 1 1 1 0 Fanconi anaemia group C protein DUF4271 PF14093.6 KXL45603.1 - 0.073 13.0 3.6 0.043 13.7 0.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) Amino_oxidase PF01593.24 KXL45604.1 - 1.2e-17 64.4 0.3 1.8e-16 60.5 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KXL45604.1 - 4.2e-12 45.9 0.1 2.5e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXL45604.1 - 1.1e-10 41.7 1.7 2.8e-10 40.3 0.2 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXL45604.1 - 2.2e-09 37.4 0.4 7.6e-09 35.7 0.4 2.0 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GDI PF00996.18 KXL45604.1 - 1.5e-06 27.0 0.0 0.014 13.9 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor FAD_binding_2 PF00890.24 KXL45604.1 - 1.6e-06 27.5 0.9 2.7e-05 23.4 0.9 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KXL45604.1 - 3.3e-06 26.1 0.4 0.0023 16.7 0.3 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 KXL45604.1 - 0.00038 19.9 0.0 0.011 15.1 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 KXL45604.1 - 0.0059 15.7 3.2 0.061 12.4 0.3 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KXL45604.1 - 0.0064 17.0 3.0 4.7 7.8 0.3 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXL45604.1 - 0.015 14.5 1.1 0.046 13.0 0.2 2.0 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 KXL45604.1 - 0.019 14.2 0.0 0.049 12.9 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXL45604.1 - 0.019 14.2 0.4 0.042 13.1 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 KXL45604.1 - 0.02 13.8 3.8 0.085 11.7 0.2 2.1 2 0 0 2 2 2 0 Tryptophan halogenase GMC_oxred_N PF00732.19 KXL45604.1 - 0.02 14.2 0.0 0.8 9.0 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase NAD_binding_9 PF13454.6 KXL45604.1 - 0.03 14.3 0.1 0.26 11.2 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding MCRA PF06100.11 KXL45604.1 - 0.034 13.0 0.3 0.33 9.7 0.0 2.1 2 0 0 2 2 2 0 MCRA family Minor_capsid_2 PF11114.8 KXL45604.1 - 0.067 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Minor capsid protein ApbA PF02558.16 KXL45604.1 - 0.073 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KXL45604.1 - 0.1 12.5 0.3 0.18 11.7 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 KXL45604.1 - 0.11 11.6 0.2 1.1 8.3 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 KXL45604.1 - 0.17 12.3 0.0 0.36 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding RPE65 PF03055.15 KXL45605.1 - 4.2e-125 418.5 0.0 5.4e-125 418.2 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein SQS_PSY PF00494.19 KXL45606.1 - 5.1e-54 183.5 0.0 7.3e-54 183.0 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase Bac_rhodopsin PF01036.18 KXL45607.1 - 3.3e-57 193.6 14.3 4.5e-57 193.2 14.3 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF1772 PF08592.11 KXL45607.1 - 1.3 9.3 8.6 0.62 10.4 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) ELP6 PF09807.9 KXL45608.1 - 8e-05 22.2 0.0 0.00017 21.1 0.0 1.4 1 1 0 1 1 1 1 Elongation complex protein 6 Elong_Iki1 PF10483.9 KXL45608.1 - 0.1 12.1 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Elongator subunit Iki1 RdRP PF05183.12 KXL45609.1 - 5.5e-178 593.3 0.0 7.3e-178 592.9 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Myb_DNA-bind_5 PF13873.6 KXL45609.1 - 0.34 11.0 3.1 4.1 7.6 0.6 2.6 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain HTH_38 PF13936.6 KXL45610.1 - 0.0064 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.22 KXL45610.1 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 MarR family Sigma70_r4 PF04545.16 KXL45610.1 - 0.016 14.7 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 KXL45610.1 - 0.033 13.9 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Tnp_Tc3_1 PF11427.8 KXL45610.1 - 0.096 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Tc3 transposase HTH_1 PF00126.27 KXL45610.1 - 0.14 12.1 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family AT_hook PF02178.19 KXL45610.1 - 0.18 11.8 2.8 0.45 10.6 2.8 1.7 1 0 0 1 1 1 0 AT hook motif UPF0122 PF04297.14 KXL45610.1 - 0.21 11.9 0.0 0.26 11.5 0.0 1.1 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like GMC_oxred_N PF00732.19 KXL45611.1 - 1.5e-09 37.7 0.0 1.7e-09 37.5 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KXL45611.1 - 9.5e-07 28.2 0.0 1e-06 28.1 0.0 1.0 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KXL45611.1 - 1.2e-05 24.7 0.1 1.5e-05 24.4 0.1 1.1 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KXL45611.1 - 3.6e-05 23.9 0.2 5.7e-05 23.3 0.2 1.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXL45611.1 - 5.2e-05 23.0 0.2 5.4e-05 22.9 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXL45611.1 - 0.00021 20.5 0.4 0.00024 20.3 0.4 1.0 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXL45611.1 - 0.0043 15.8 0.1 0.0051 15.6 0.1 1.0 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 KXL45611.1 - 0.0064 15.8 0.1 0.0068 15.7 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXL45611.1 - 0.011 15.0 0.0 0.012 14.9 0.0 1.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXL45611.1 - 0.041 13.9 0.1 0.045 13.7 0.1 1.1 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KXL45611.1 - 0.15 10.8 0.1 0.17 10.7 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Malic_M PF03949.15 KXL45611.1 - 0.2 10.9 0.0 0.21 10.8 0.0 1.1 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain FMO-like PF00743.19 KXL45612.1 - 1.3e-15 56.8 0.0 2.3e-10 39.5 0.0 2.9 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXL45612.1 - 1.3e-12 47.6 0.0 7.3e-11 41.8 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXL45612.1 - 8.2e-09 35.1 0.2 2.6e-06 26.9 0.3 3.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXL45612.1 - 6.5e-07 29.3 0.4 0.17 11.4 0.4 3.2 2 1 0 3 3 3 3 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXL45612.1 - 5.9e-06 26.4 0.0 5.2e-05 23.4 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXL45612.1 - 0.0019 17.0 0.1 0.0064 15.2 0.1 1.8 1 1 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 KXL45612.1 - 0.0025 17.8 4.6 0.026 14.5 0.1 3.7 4 1 0 4 4 4 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KXL45612.1 - 0.013 14.6 0.0 0.028 13.5 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.24 KXL45612.1 - 0.021 14.1 0.0 0.042 13.1 0.0 1.5 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Thi4 PF01946.17 KXL45612.1 - 0.027 13.7 0.1 0.048 12.9 0.1 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 KXL45612.1 - 0.031 13.5 0.2 0.055 12.7 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain K_oxygenase PF13434.6 KXL45612.1 - 0.048 12.8 0.7 0.23 10.5 0.0 2.4 3 1 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 KXL45612.1 - 0.056 12.7 0.2 1 8.6 0.2 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain MCRA PF06100.11 KXL45612.1 - 0.13 11.0 0.0 0.24 10.1 0.0 1.4 1 0 0 1 1 1 0 MCRA family GIDA PF01134.22 KXL45612.1 - 0.14 11.2 0.0 0.14 11.2 0.0 1.9 3 0 0 3 3 3 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KXL45612.1 - 0.2 10.9 1.8 0.23 10.7 0.4 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Fungal_trans_2 PF11951.8 KXL45613.1 - 0.00037 19.4 0.3 0.0007 18.5 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain MOSC PF03473.17 KXL45615.1 - 1.7e-32 112.2 0.0 2.3e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KXL45615.1 - 1.8e-08 34.2 0.0 3.7e-08 33.3 0.0 1.6 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain YrbL-PhoP_reg PF10707.9 KXL45615.1 - 0.17 11.4 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Patatin PF01734.22 KXL45616.1 - 2.3e-15 57.4 0.0 3.9e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Glyco_transf_8 PF01501.20 KXL45617.1 - 0.00017 21.2 0.3 0.032 13.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 8 Thx PF17070.5 KXL45617.1 - 0.14 12.3 0.2 0.34 11.1 0.2 1.6 1 0 0 1 1 1 0 30S ribosomal protein Thx Mannosyl_trans3 PF11051.8 KXL45617.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative SLD5_C PF16922.5 KXL45618.1 - 1.1e-18 67.1 0.0 1.8e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 KXL45618.1 - 0.00011 22.6 0.1 0.00026 21.4 0.1 1.6 1 1 0 1 1 1 1 GINS complex protein DLH PF01738.18 KXL45619.1 - 6e-17 61.9 0.1 1.1e-14 54.5 0.1 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 KXL45619.1 - 0.014 15.2 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Vac14_Fig4_bd PF11916.8 KXL45620.1 - 2.7e-76 255.2 8.9 2.7e-76 255.2 8.9 2.2 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 KXL45620.1 - 3.5e-46 155.7 0.4 1.2e-42 144.4 0.0 4.2 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KXL45620.1 - 1.1e-10 41.7 5.2 0.00033 21.1 0.1 5.5 6 0 0 6 6 6 2 HEAT-like repeat HEAT PF02985.22 KXL45620.1 - 1e-07 31.6 1.9 0.0035 17.5 0.0 6.8 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.7 KXL45620.1 - 3.2e-07 30.5 3.5 0.14 12.2 0.3 3.9 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXL45620.1 - 2.9e-06 27.6 3.2 0.11 12.9 0.0 4.9 4 0 0 4 4 4 1 HEAT repeats Arm PF00514.23 KXL45620.1 - 0.0023 17.9 0.7 41 4.4 0.0 5.3 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat ParcG PF10274.9 KXL45620.1 - 0.024 14.7 2.1 4 7.5 0.1 2.8 3 0 0 3 3 3 0 Parkin co-regulated protein UME PF08064.13 KXL45620.1 - 0.039 13.9 0.9 24 4.9 0.1 3.4 3 0 0 3 3 3 0 UME (NUC010) domain DUF3385 PF11865.8 KXL45620.1 - 0.056 13.3 0.1 21 5.0 0.0 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF3385) EI24 PF07264.11 KXL45621.1 - 2.2e-13 50.8 11.0 2.9e-13 50.5 11.0 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF2417 PF10329.9 KXL45621.1 - 0.13 11.7 8.5 0.017 14.6 4.4 1.6 2 0 0 2 2 2 0 Region of unknown function (DUF2417) FA_desaturase PF00487.24 KXL45621.1 - 2.4 7.9 14.2 0.19 11.5 2.8 2.2 2 0 0 2 2 2 0 Fatty acid desaturase MIF4G PF02854.19 KXL45622.1 - 2.7e-20 72.9 4.3 6.3e-20 71.7 2.4 2.2 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 KXL45622.1 - 1e-19 70.6 0.3 2.3e-19 69.4 0.1 1.8 2 0 0 2 2 2 1 MA3 domain Transposase_31 PF04754.12 KXL45622.1 - 0.11 12.0 0.5 0.48 10.0 0.1 2.3 2 1 1 3 3 3 0 Putative transposase, YhgA-like Tn7_Tnp_TnsA_C PF08721.11 KXL45622.1 - 2.2 9.0 4.2 3.6 8.3 0.1 3.5 4 1 1 5 5 5 0 TnsA endonuclease C terminal SRP14 PF02290.15 KXL45623.1 - 4e-27 94.4 0.0 6.4e-27 93.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle 14kD protein Vps36_ESCRT-II PF11605.8 KXL45623.1 - 0.024 14.8 0.0 0.43 10.8 0.0 2.2 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.20 KXL45623.1 - 0.13 12.1 0.0 0.18 11.7 0.0 1.4 1 1 0 1 1 1 0 GRAM domain PP2C PF00481.21 KXL45624.1 - 1.4e-51 175.6 0.0 2.5e-51 174.8 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 KXL45624.1 - 1.3e-42 143.3 67.7 2.8e-09 36.6 3.4 11.7 6 4 8 15 15 15 11 Leucine rich repeat LRR_4 PF12799.7 KXL45624.1 - 1.6e-37 126.8 69.1 1.7e-05 25.1 0.9 13.6 7 1 6 16 16 16 13 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 KXL45624.1 - 9.6e-30 103.6 0.0 3.7e-29 101.6 0.0 1.8 1 1 1 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.33 KXL45624.1 - 3e-08 33.1 49.1 1.3 9.8 0.1 16.4 17 2 0 17 17 17 2 Leucine Rich Repeat Ad_cyc_g-alpha PF08509.11 KXL45624.1 - 8.4e-08 31.8 0.2 2.5e-07 30.3 0.2 1.7 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_9 PF14580.6 KXL45624.1 - 5.3e-05 22.8 19.3 0.006 16.1 0.6 5.3 2 1 4 6 6 6 4 Leucine-rich repeat LRR_5 PF13306.6 KXL45624.1 - 0.00023 21.1 0.0 2.2 8.3 0.0 4.1 4 0 0 4 4 4 1 BspA type Leucine rich repeat region (6 copies) RA PF00788.23 KXL45624.1 - 0.00029 21.4 0.0 0.00093 19.8 0.0 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Mpp10 PF04006.12 KXL45625.1 - 0.028 12.9 2.8 0.04 12.4 2.8 1.1 1 0 0 1 1 1 0 Mpp10 protein CinA PF02464.17 KXL45626.1 - 3.4e-35 120.9 0.2 3.8e-35 120.7 0.2 1.0 1 0 0 1 1 1 1 Competence-damaged protein PrpF PF04303.13 KXL45627.1 - 6.1e-99 331.5 0.1 7.6e-99 331.2 0.1 1.0 1 0 0 1 1 1 1 PrpF protein Polyoma_agno PF01736.16 KXL45627.1 - 0.075 12.8 0.3 0.17 11.6 0.3 1.6 1 0 0 1 1 1 0 Polyomavirus agnoprotein Peptidase_C15 PF01470.17 KXL45630.1 - 7.9e-11 42.5 0.0 5.7e-08 33.2 0.0 2.4 2 0 0 2 2 2 2 Pyroglutamyl peptidase Sua5_yciO_yrdC PF01300.18 KXL45631.1 - 1.2e-49 168.2 0.0 1.8e-49 167.6 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 KXL45631.1 - 4.7e-29 101.6 0.0 1.1e-28 100.4 0.0 1.6 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding Amino_oxidase PF01593.24 KXL45632.1 - 7.9e-34 117.7 0.2 1.5e-32 113.5 0.2 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXL45632.1 - 5.1e-14 52.2 0.0 2.4e-13 50.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXL45632.1 - 6.7e-08 32.5 0.0 4.9e-06 26.4 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXL45632.1 - 4.9e-05 23.8 0.0 0.13 12.9 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXL45632.1 - 8.3e-05 21.9 0.0 0.00014 21.2 0.0 1.2 1 0 0 1 1 1 1 Thi4 family MCRA PF06100.11 KXL45632.1 - 0.0013 17.6 0.0 0.0021 16.9 0.0 1.3 1 0 0 1 1 1 1 MCRA family Pyr_redox_2 PF07992.14 KXL45632.1 - 0.025 13.8 0.0 0.17 11.1 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_transf_34 PF05637.12 KXL45633.1 - 0.022 14.5 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family Glyco_hydro_12 PF01670.16 KXL45633.1 - 0.091 12.7 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 12 Arylsulfotran_2 PF14269.6 KXL45634.1 - 8.6e-40 137.0 2.9 1.3e-39 136.4 2.9 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXL45634.1 - 1.2e-12 47.5 0.3 1.2e-10 40.9 0.3 2.3 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Pectate_lyase_3 PF12708.7 KXL45635.1 - 2.2e-08 34.2 0.6 3.1e-08 33.7 0.6 1.2 1 0 0 1 1 1 1 Pectate lyase superfamily protein End_N_terminal PF12218.8 KXL45635.1 - 0.0088 15.7 2.1 0.0097 15.6 0.5 1.8 2 0 0 2 2 2 1 N terminal extension of bacteriophage endosialidase DUF3176 PF11374.8 KXL45637.1 - 2.5e-32 111.3 1.2 2.5e-32 111.3 1.2 2.4 3 1 0 3 3 3 1 Protein of unknown function (DUF3176) S_4TM PF18159.1 KXL45637.1 - 0.37 10.0 2.6 0.77 9.0 0.3 2.0 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain MFS_1 PF07690.16 KXL45638.1 - 1.2e-35 123.1 26.5 1.2e-35 123.1 26.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily PAP2 PF01569.21 KXL45638.1 - 9.3 6.0 12.1 0.23 11.2 1.6 3.1 2 1 1 3 3 3 0 PAP2 superfamily Polyketide_cyc2 PF10604.9 KXL45639.1 - 1.6e-06 28.4 0.1 2e-06 28.2 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport WHH PF14414.6 KXL45639.1 - 0.12 12.3 0.2 0.46 10.4 0.2 1.8 1 1 0 1 1 1 0 A nuclease of the HNH/ENDO VII superfamily with conserved WHH PI-PLC-X PF00388.19 KXL45640.1 - 0.13 11.9 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Tyrosinase PF00264.20 KXL45641.1 - 1.1e-48 166.5 0.1 1.4e-48 166.1 0.1 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase FAD_binding_4 PF01565.23 KXL45642.1 - 9.5e-28 96.7 0.0 1.5e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 KXL45642.1 - 3.8e-10 39.8 0.2 6.4e-10 39.1 0.2 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain PPR_3 PF13812.6 KXL45642.1 - 0.033 14.3 0.0 0.085 12.9 0.0 1.6 1 0 0 1 1 1 0 Pentatricopeptide repeat domain CMD PF02627.20 KXL45643.1 - 1.9e-12 47.0 0.3 3.3e-07 30.2 0.1 2.5 2 1 0 2 2 2 2 Carboxymuconolactone decarboxylase family NAD_binding_2 PF03446.15 KXL45644.1 - 3.5e-31 108.5 0.1 6.4e-31 107.7 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXL45644.1 - 7.1e-24 84.4 0.0 1.1e-23 83.8 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.15 KXL45644.1 - 1.2e-05 24.4 0.0 2.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.17 KXL45644.1 - 3.4e-05 24.4 0.0 8.7e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 KXL45644.1 - 0.0017 18.0 0.0 0.0034 17.0 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain GFO_IDH_MocA PF01408.22 KXL45644.1 - 0.028 15.2 0.0 0.14 13.0 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold LuxS PF02664.15 KXL45644.1 - 0.13 11.9 0.0 0.55 9.9 0.0 2.0 1 1 0 1 1 1 0 S-Ribosylhomocysteinase (LuxS) FAD_binding_3 PF01494.19 KXL45646.1 - 6.2e-45 154.0 0.0 7.6e-45 153.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KXL45646.1 - 7.5e-05 22.0 0.0 0.00012 21.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXL45646.1 - 0.00037 20.2 0.0 0.0016 18.1 0.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXL45646.1 - 0.00042 20.5 0.0 0.0013 19.0 0.0 1.8 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXL45646.1 - 0.004 15.9 0.0 0.0074 15.0 0.0 1.4 2 0 0 2 2 2 1 HI0933-like protein ApbA PF02558.16 KXL45646.1 - 0.0079 15.9 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 KXL45646.1 - 0.0091 15.3 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SEP PF08059.13 KXL45646.1 - 0.023 15.3 0.0 0.62 10.7 0.0 2.4 2 0 0 2 2 2 0 SEP domain GIDA PF01134.22 KXL45646.1 - 0.04 13.0 0.0 0.054 12.6 0.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 KXL45646.1 - 0.042 13.1 0.0 0.08 12.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KXL45646.1 - 0.043 12.8 0.0 0.065 12.3 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 KXL45646.1 - 0.051 14.1 0.0 0.17 12.4 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KXL45646.1 - 0.068 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 KXL45646.1 - 0.086 12.1 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXL45646.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase p450 PF00067.22 KXL45647.1 - 1.5e-21 76.7 0.0 2.2e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_1 PF00583.25 KXL45648.1 - 5.8e-06 26.5 0.0 9.7e-06 25.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXL45648.1 - 3.2e-05 24.3 0.0 5.7e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXL45648.1 - 0.00039 20.4 0.0 0.00083 19.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain nlz1 PF12402.8 KXL45648.1 - 0.12 12.8 0.0 5.7 7.4 0.0 2.3 2 0 0 2 2 2 0 NocA-like zinc-finger protein 1 DUF3611 PF12263.8 KXL45649.1 - 0.12 12.2 3.2 0.99 9.3 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) Cytochrom_B559 PF00283.19 KXL45649.1 - 0.18 11.3 4.8 0.11 12.0 1.1 2.4 2 0 0 2 2 2 0 Cytochrome b559, alpha (gene psbE) and beta (gene psbF)subunits GFA PF04828.14 KXL45650.1 - 4e-09 36.7 0.2 5.6e-08 33.0 0.2 2.2 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Mtc PF03820.17 KXL45651.1 - 3.3e-122 407.4 0.0 3.7e-122 407.2 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier MoaC PF01967.21 KXL45652.1 - 4.7e-49 166.0 0.0 8.1e-49 165.2 0.0 1.4 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 KXL45652.1 - 6.4e-38 129.6 0.1 1.7e-36 125.0 0.0 2.3 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KXL45652.1 - 2.6e-20 73.4 0.0 6e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KXL45652.1 - 0.045 14.0 0.1 0.16 12.2 0.0 1.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain TAF4 PF05236.14 KXL45653.1 - 1.1e-29 104.0 10.6 1.6e-28 100.3 10.6 2.3 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family CPSF73-100_C PF11718.8 KXL45654.1 - 6e-80 267.9 0.1 8.4e-80 267.4 0.1 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 KXL45654.1 - 1.6e-29 102.4 0.0 3.7e-29 101.2 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 KXL45654.1 - 1.6e-20 73.9 0.6 3e-20 73.1 0.6 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 KXL45654.1 - 1.3e-17 63.9 0.1 2.2e-17 63.1 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 KXL45654.1 - 5.3e-12 45.5 0.0 1.2e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 KXL45654.1 - 3.9e-06 26.5 0.9 1.9e-05 24.2 0.9 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXL45654.1 - 5.2e-05 23.2 0.2 0.00017 21.5 0.2 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 KXL45654.1 - 0.00069 18.9 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 Putative beta-lactamase-like family IRK_N PF08466.10 KXL45654.1 - 0.0089 16.2 0.6 0.032 14.4 0.6 2.0 1 0 0 1 1 1 1 Inward rectifier potassium channel N-terminal Acetyltransf_4 PF13420.7 KXL45655.1 - 0.0014 18.8 0.0 0.051 13.7 0.0 3.1 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXL45655.1 - 0.011 16.2 0.0 0.08 13.4 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXL45655.1 - 0.011 15.9 0.1 0.089 13.0 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family GNAT_acetyltran PF12746.7 KXL45655.1 - 0.035 13.7 0.0 0.082 12.5 0.0 1.5 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_13 PF13880.6 KXL45655.1 - 0.15 12.1 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Arf PF00025.21 KXL45656.1 - 3.4e-65 218.7 0.5 3.9e-65 218.6 0.5 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KXL45656.1 - 2.4e-12 47.1 0.1 3.4e-12 46.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KXL45656.1 - 5.8e-12 45.4 1.3 1.1e-06 28.1 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KXL45656.1 - 1.8e-11 43.9 0.0 2e-11 43.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KXL45656.1 - 5.5e-09 35.7 0.0 6.4e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXL45656.1 - 1.2e-07 31.8 0.0 3e-07 30.5 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 KXL45656.1 - 1.2e-05 24.8 0.0 1.3e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KXL45656.1 - 0.00015 21.4 0.0 0.0027 17.3 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KXL45656.1 - 0.013 15.1 0.4 0.04 13.4 0.4 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.9 KXL45656.1 - 0.12 12.1 0.0 0.37 10.5 0.1 1.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation 6PF2K PF01591.18 KXL45656.1 - 0.15 11.4 0.0 0.31 10.3 0.0 1.6 2 0 0 2 2 2 0 6-phosphofructo-2-kinase DUF2617 PF10936.8 KXL45656.1 - 0.2 11.7 0.0 0.41 10.7 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF2617 DUF4045 PF13254.6 KXL45657.1 - 2.7e-99 333.7 33.8 2.7e-99 333.7 33.8 5.4 3 2 1 5 5 5 1 Domain of unknown function (DUF4045) Gelsolin PF00626.22 KXL45658.1 - 5.9e-13 48.5 0.0 7.1e-05 22.6 0.0 3.4 3 0 0 3 3 3 3 Gelsolin repeat XRN1_DBM PF18245.1 KXL45658.1 - 0.33 11.0 2.4 0.69 10.0 1.4 2.1 1 1 1 2 2 2 0 5-3 exonuclease XRN1 DCP1-binding motif AAA_2 PF07724.14 KXL45659.1 - 9.3e-47 159.3 0.9 3.4e-45 154.2 0.0 3.4 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KXL45659.1 - 1.2e-33 115.1 2.6 1.2e-33 115.1 2.6 4.6 4 1 1 5 5 4 1 AAA lid domain AAA PF00004.29 KXL45659.1 - 1.9e-26 93.0 0.0 2.9e-14 53.6 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KXL45659.1 - 4.5e-25 87.5 0.3 1.6e-24 85.7 0.3 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KXL45659.1 - 3.5e-15 56.2 0.0 3.2e-09 36.9 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXL45659.1 - 5.3e-13 49.4 0.1 4.6e-05 23.7 0.0 4.5 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.6 KXL45659.1 - 8.2e-12 45.8 13.7 1.4e-06 28.8 0.1 5.5 4 3 0 5 5 5 2 AAA ATPase domain Sigma54_activat PF00158.26 KXL45659.1 - 1.6e-08 34.5 0.0 3e-05 23.8 0.0 2.6 2 1 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 KXL45659.1 - 2.4e-06 27.4 0.0 0.081 12.6 0.0 3.1 3 0 0 3 3 3 2 IstB-like ATP binding protein Clp_N PF02861.20 KXL45659.1 - 3.8e-06 26.9 0.3 0.12 12.6 0.0 3.5 3 0 0 3 3 2 2 Clp amino terminal domain, pathogenicity island component AAA_7 PF12775.7 KXL45659.1 - 5.7e-06 26.0 0.0 0.019 14.5 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 KXL45659.1 - 7.3e-06 26.1 0.0 0.25 11.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KXL45659.1 - 1.4e-05 24.6 0.2 0.12 11.8 0.1 3.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KXL45659.1 - 1.6e-05 25.1 0.1 0.27 11.4 0.0 3.6 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KXL45659.1 - 8.1e-05 23.0 0.0 0.56 10.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase ATPase_2 PF01637.18 KXL45659.1 - 8.6e-05 22.6 9.3 0.11 12.4 0.3 4.9 4 1 0 4 4 3 2 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KXL45659.1 - 0.00011 22.0 0.0 0.12 12.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXL45659.1 - 0.00016 21.5 0.0 0.9 9.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 KXL45659.1 - 0.00019 21.4 0.0 0.29 11.2 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KXL45659.1 - 0.00028 21.4 8.3 0.13 12.8 0.0 4.6 3 2 1 4 4 3 2 AAA domain AAA_3 PF07726.11 KXL45659.1 - 0.00031 20.6 0.0 1.1 9.2 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KXL45659.1 - 0.00038 20.4 0.0 0.57 10.1 0.0 3.2 2 1 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 KXL45659.1 - 0.00072 20.1 3.2 1 9.9 0.0 4.0 4 1 0 4 4 2 1 ABC transporter RuvB_N PF05496.12 KXL45659.1 - 0.00081 19.2 2.0 4.6 7.0 0.8 4.3 3 1 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 KXL45659.1 - 0.0019 17.9 0.1 1.8 8.3 0.0 2.8 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_19 PF13245.6 KXL45659.1 - 0.002 18.5 0.2 0.37 11.1 0.2 3.2 2 1 0 2 2 2 1 AAA domain Roc PF08477.13 KXL45659.1 - 0.0036 17.5 0.0 1.1 9.5 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 KXL45659.1 - 0.0042 16.7 0.3 0.48 10.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain Torsin PF06309.11 KXL45659.1 - 0.0048 17.0 0.0 0.037 14.1 0.0 2.3 2 0 0 2 2 2 1 Torsin NTPase_1 PF03266.15 KXL45659.1 - 0.0062 16.5 0.0 0.13 12.1 0.0 2.8 2 0 0 2 2 2 1 NTPase NACHT PF05729.12 KXL45659.1 - 0.0068 16.3 0.0 0.48 10.3 0.0 2.6 2 0 0 2 2 2 1 NACHT domain SRP54 PF00448.22 KXL45659.1 - 0.011 15.4 0.0 1.7 8.2 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 KXL45659.1 - 0.011 16.0 7.9 0.6 10.3 0.0 3.5 4 0 0 4 4 2 0 AAA domain T2SSE PF00437.20 KXL45659.1 - 0.013 14.6 0.0 0.013 14.6 0.0 3.1 4 0 0 4 4 4 0 Type II/IV secretion system protein ResIII PF04851.15 KXL45659.1 - 0.02 14.9 0.2 5.5 7.0 0.0 3.8 4 0 0 4 4 3 0 Type III restriction enzyme, res subunit V_ATPase_I PF01496.19 KXL45659.1 - 0.049 11.6 6.7 0.072 11.0 6.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CbiA PF01656.23 KXL45659.1 - 0.072 13.2 0.0 41 4.2 0.0 3.8 4 0 0 4 4 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain GAS PF13851.6 KXL45659.1 - 0.088 12.1 21.1 0.24 10.7 21.1 1.7 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding MPS2 PF17060.5 KXL45659.1 - 0.36 10.1 7.8 0.83 8.9 7.8 1.6 1 0 0 1 1 1 0 Monopolar spindle protein 2 AAA_23 PF13476.6 KXL45659.1 - 0.39 11.2 0.0 0.39 11.2 0.0 5.1 5 1 0 5 5 2 0 AAA domain TMF_TATA_bd PF12325.8 KXL45659.1 - 0.9 9.8 19.8 0.2 11.9 14.0 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Exonuc_VII_L PF02601.15 KXL45659.1 - 0.92 9.0 9.1 1.9 8.0 9.1 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 KXL45659.1 - 2.1 7.3 10.2 4.2 6.3 10.2 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 KXL45659.1 - 3.3 6.5 20.5 6.7 5.5 20.5 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein UBX PF00789.20 KXL45660.1 - 3.7e-13 49.5 0.0 7.3e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 KXL45660.1 - 2.1e-11 43.5 0.5 5.6e-11 42.1 0.5 1.8 1 0 0 1 1 1 1 UBA-like domain DUF1682 PF07946.14 KXL45660.1 - 0.0081 15.4 6.0 0.013 14.8 6.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) SpoVR PF04293.13 KXL45660.1 - 0.2 10.3 6.3 0.31 9.7 6.3 1.2 1 0 0 1 1 1 0 SpoVR like protein Med19 PF10278.9 KXL45660.1 - 0.21 11.5 4.2 0.34 10.8 4.2 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 PRTP PF01366.18 KXL45660.1 - 0.91 7.5 9.5 1.3 7.0 9.5 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Presenilin PF01080.17 KXL45660.1 - 4.5 5.9 6.3 6.6 5.4 6.3 1.2 1 0 0 1 1 1 0 Presenilin TerB_C PF15615.6 KXL45660.1 - 8.5 6.7 13.1 24 5.2 13.1 1.8 1 0 0 1 1 1 0 TerB-C domain Pan3_PK PF18101.1 KXL45661.1 - 1.2e-54 184.1 0.3 1.3e-52 177.4 0.3 2.3 1 1 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KXL45661.1 - 1.2e-05 24.8 0.0 2.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 KXL45662.1 - 4.2e-46 157.4 0.0 1.2e-45 156.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL45662.1 - 4.7e-14 52.3 0.0 1.7e-13 50.5 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase SRP19 PF01922.17 KXL45663.1 - 2.1e-33 115.2 0.2 3.1e-33 114.6 0.2 1.3 1 0 0 1 1 1 1 SRP19 protein NPH3 PF03000.14 KXL45663.1 - 0.038 13.7 0.1 0.058 13.0 0.1 1.2 1 0 0 1 1 1 0 NPH3 family Aminotran_3 PF00202.21 KXL45664.1 - 6.6e-82 275.3 0.0 9.1e-82 274.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Prp18 PF02840.15 KXL45666.1 - 2.1e-48 164.0 1.3 3.4e-48 163.3 0.0 1.9 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 KXL45666.1 - 3.9e-12 45.5 1.2 3.9e-12 45.5 1.2 2.8 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like CCDC71L PF15374.6 KXL45666.1 - 0.76 9.0 9.2 1.1 8.4 9.2 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L GBP_C PF02841.14 KXL45666.1 - 1.1 8.6 12.8 1.5 8.2 12.8 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain CDC27 PF09507.10 KXL45666.1 - 1.9 7.8 15.5 2.6 7.4 15.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RR_TM4-6 PF06459.12 KXL45666.1 - 6.6 6.5 9.9 11 5.7 9.9 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Borrelia_P83 PF05262.11 KXL45666.1 - 9.3 4.6 13.8 13 4.1 13.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein SAP18 PF06487.12 KXL45667.1 - 2.3e-31 108.8 0.0 2.9e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) DUF3097 PF11296.8 KXL45669.1 - 0.076 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3097) SE PF08491.10 KXL45669.1 - 0.12 11.5 0.1 0.21 10.6 0.1 1.3 1 0 0 1 1 1 0 Squalene epoxidase Exo_endo_phos_2 PF14529.6 KXL45671.1 - 2.4e-12 46.7 0.1 2.5e-12 46.7 0.1 1.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KXL45671.1 - 0.0034 16.9 0.3 0.0037 16.8 0.3 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ubiquitin PF00240.23 KXL45672.1 - 6.7e-34 115.5 0.5 7.5e-34 115.3 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KXL45672.1 - 3.4e-15 55.6 0.4 3.8e-15 55.5 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KXL45672.1 - 6.5e-06 26.5 0.1 2.9e-05 24.4 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 KXL45672.1 - 0.0013 19.0 0.1 0.0015 18.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KXL45672.1 - 0.0016 18.4 0.0 0.0018 18.1 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KXL45672.1 - 0.0035 17.4 0.0 0.008 16.3 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 KXL45672.1 - 0.019 15.0 0.2 2.5 8.2 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 KXL45672.1 - 0.019 15.5 0.1 0.023 15.3 0.1 1.1 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain AMP-binding PF00501.28 KXL45673.1 - 2.2e-58 197.9 0.0 2.7e-58 197.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXL45673.1 - 1.3e-06 29.3 0.0 2.8e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Chitin_synth_2 PF03142.15 KXL45674.1 - 7.8e-22 77.6 2.4 3e-21 75.6 1.5 2.6 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KXL45674.1 - 2.7e-16 60.1 2.1 2.7e-16 60.1 2.1 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXL45674.1 - 1.4e-11 44.7 0.0 4.1e-11 43.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KXL45674.1 - 0.0017 18.2 0.0 0.19 11.5 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 G-alpha PF00503.20 KXL45676.1 - 2.8e-116 388.6 0.2 3.2e-116 388.4 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KXL45676.1 - 2.3e-15 56.5 1.3 1.6e-10 40.7 0.2 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KXL45676.1 - 1.7e-05 24.3 0.0 0.064 12.6 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KXL45676.1 - 0.0025 18.0 0.2 1.1 9.5 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KXL45676.1 - 0.093 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pkinase PF00069.25 KXL45679.1 - 4e-66 223.1 0.0 5.1e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL45679.1 - 3e-32 111.9 0.0 3.9e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXL45679.1 - 3.6e-06 26.2 0.1 4.7e-06 25.8 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KXL45679.1 - 7.1e-05 22.3 0.0 0.00017 21.0 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXL45679.1 - 0.00053 19.4 0.0 0.037 13.4 0.0 2.3 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 KXL45679.1 - 0.00064 19.7 0.0 0.0015 18.5 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KXL45679.1 - 0.0053 16.4 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 KXL45679.1 - 0.01 15.5 0.2 0.022 14.4 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Get5_C PF18514.1 KXL45679.1 - 0.12 12.2 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 Get5 C-terminal domain Myb_DNA-bind_7 PF15963.5 KXL45679.1 - 0.41 10.6 1.2 0.7 9.8 0.2 1.9 2 0 0 2 2 2 0 Myb DNA-binding like Avl9 PF09794.9 KXL45680.1 - 4e-137 456.9 0.0 5e-137 456.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 KXL45680.1 - 2.9e-10 40.1 0.6 2.6e-05 24.1 0.0 2.3 1 1 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.9 KXL45680.1 - 1.9e-08 34.2 2.9 1.4e-06 28.1 0.7 3.3 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) SBBP PF06739.11 KXL45680.1 - 0.087 12.8 0.0 2.6 8.1 0.0 2.4 2 0 0 2 2 2 0 Beta-propeller repeat DENN PF02141.21 KXL45680.1 - 0.12 12.3 1.8 0.2 11.6 0.3 2.0 2 1 0 2 2 2 0 DENN (AEX-3) domain MMS1_N PF10433.9 KXL45681.1 - 1.2e-68 232.0 0.0 1.9e-68 231.3 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Kelch_6 PF13964.6 KXL45681.1 - 0.012 15.8 0.2 0.59 10.5 0.0 3.0 2 0 0 2 2 2 0 Kelch motif RabGAP-TBC PF00566.18 KXL45682.1 - 3.4e-25 89.0 0.0 6e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF5632 PF18646.1 KXL45682.1 - 0.13 12.4 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5632) Aminotran_5 PF00266.19 KXL45683.1 - 1.3e-15 57.2 0.0 2e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KXL45683.1 - 0.00085 18.6 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KXL45683.1 - 0.032 13.5 0.0 1.3 8.3 0.0 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF2034 PF10356.9 KXL45684.1 - 2.6e-24 85.7 0.0 4.6e-11 42.5 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 KXL45684.1 - 1.5e-06 28.2 0.0 2.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease adh_short PF00106.25 KXL45685.1 - 1.7e-41 141.9 0.1 2.4e-41 141.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL45685.1 - 3.7e-36 124.9 0.2 8.4e-36 123.7 0.2 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL45685.1 - 1.1e-08 35.2 3.1 1.2e-08 35.1 0.9 2.0 2 0 0 2 2 2 1 KR domain GST_N PF02798.20 KXL45686.1 - 4.2e-17 62.2 0.0 9.3e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXL45686.1 - 1.4e-16 60.6 0.0 3e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXL45686.1 - 3.2e-15 56.1 0.0 5.3e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXL45686.1 - 2e-11 44.0 0.0 4.2e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXL45686.1 - 4.8e-11 42.7 0.0 7.3e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXL45686.1 - 1.9e-07 31.0 0.0 3.4e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain F-box PF00646.33 KXL45687.1 - 0.038 13.9 2.1 0.15 12.0 2.1 2.0 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KXL45687.1 - 0.072 13.0 1.5 0.24 11.3 1.5 1.9 1 0 0 1 1 1 0 F-box-like PARP PF00644.20 KXL45688.1 - 3.9e-53 179.9 0.0 6.2e-53 179.3 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KXL45688.1 - 1.3e-42 145.2 0.0 1.9e-42 144.6 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 KXL45688.1 - 4.4e-21 74.7 0.1 8.2e-21 73.9 0.1 1.5 1 0 0 1 1 1 1 WGR domain DUF902 PF06001.13 KXL45688.1 - 0.3 11.6 1.6 1.1 9.8 0.2 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF902) EamA PF00892.20 KXL45689.1 - 2.8e-09 37.2 28.5 1.2e-07 32.0 5.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 KXL45689.1 - 0.00017 21.0 14.1 0.0013 18.1 14.1 1.9 1 1 0 1 1 1 1 Triose-phosphate Transporter family IBN_N PF03810.19 KXL45690.1 - 2e-09 37.2 2.1 2.6e-07 30.4 0.0 4.2 4 0 0 4 4 4 1 Importin-beta N-terminal domain Cse1 PF08506.10 KXL45690.1 - 2.6e-05 23.2 0.0 8.2e-05 21.6 0.0 1.9 1 0 0 1 1 1 1 Cse1 Sigma70_ner PF04546.13 KXL45690.1 - 0.0069 16.3 2.3 0.021 14.7 2.3 1.8 1 0 0 1 1 1 1 Sigma-70, non-essential region Xpo1 PF08389.12 KXL45690.1 - 0.011 15.8 2.1 0.39 10.8 0.0 4.2 6 1 0 6 6 6 0 Exportin 1-like protein RTP1_C1 PF10363.9 KXL45690.1 - 0.016 15.4 0.4 0.54 10.5 0.1 3.1 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 RIX1 PF08167.12 KXL45690.1 - 0.034 13.9 0.2 1.3 8.8 0.0 3.4 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.6 KXL45690.1 - 1.4 9.5 5.1 20 5.8 0.3 4.8 6 0 0 6 6 6 0 HEAT-like repeat DSHCT PF08148.12 KXL45691.1 - 5.2e-50 169.3 0.1 1.4e-49 167.9 0.1 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 KXL45691.1 - 1.6e-39 134.8 0.0 3.5e-39 133.7 0.0 1.6 1 0 0 1 1 1 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 KXL45691.1 - 1.5e-22 80.9 1.7 2.3e-22 80.2 1.7 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 KXL45691.1 - 6.8e-19 68.3 0.0 1.9e-18 66.9 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXL45691.1 - 9e-07 29.2 0.0 3e-06 27.6 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL45691.1 - 3.8e-06 27.0 0.0 1e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Peptidase_S66C PF17676.1 KXL45691.1 - 0.1 13.2 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 LD-carboxypeptidase C-terminal domain FrhB_FdhB_C PF04432.13 KXL45691.1 - 0.11 12.3 0.3 0.89 9.4 0.0 2.2 2 0 0 2 2 2 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus Tfb2 PF03849.14 KXL45692.1 - 1.3e-134 448.7 0.0 2e-134 448.1 0.0 1.3 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KXL45692.1 - 6.5e-16 58.5 0.2 1.6e-15 57.3 0.2 1.7 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KXL45692.1 - 6.3e-05 23.1 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pex14_N PF04695.13 KXL45694.1 - 1.4e-36 126.5 6.4 1.4e-36 126.5 6.4 3.3 2 2 0 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Baculo_PEP_C PF04513.12 KXL45694.1 - 0.00069 19.7 1.1 0.022 14.8 0.1 2.5 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1043 PF06295.12 KXL45694.1 - 0.016 15.2 5.3 0.11 12.5 5.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) UPF0242 PF06785.11 KXL45694.1 - 0.03 14.4 6.1 0.05 13.7 6.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus V-SNARE_C PF12352.8 KXL45694.1 - 0.032 14.5 0.4 0.15 12.4 0.0 2.2 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Nup88 PF10168.9 KXL45694.1 - 0.045 11.6 7.1 0.057 11.2 7.1 1.1 1 0 0 1 1 1 0 Nuclear pore component DUF3584 PF12128.8 KXL45694.1 - 0.38 8.2 9.9 0.53 7.7 9.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FUSC PF04632.12 KXL45694.1 - 0.73 8.3 2.6 1.3 7.5 2.6 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family GrpE PF01025.19 KXL45694.1 - 3 7.5 17.4 0.063 12.9 10.7 1.5 2 0 0 2 2 2 0 GrpE YlqD PF11068.8 KXL45694.1 - 3.1 8.2 8.8 3.5 8.0 6.9 2.0 1 1 1 2 2 2 0 YlqD protein ERM PF00769.19 KXL45694.1 - 8.3 6.2 23.7 17 5.1 23.8 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family TMPIT PF07851.13 KXL45694.1 - 9.1 5.4 6.0 17 4.5 6.0 1.4 1 0 0 1 1 1 0 TMPIT-like protein DUF2235 PF09994.9 KXL45695.1 - 1.1e-80 271.1 0.0 1.4e-80 270.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) SAC3_GANP PF03399.16 KXL45696.1 - 0.00078 18.9 0.2 0.0012 18.3 0.2 1.2 1 0 0 1 1 1 1 SAC3/GANP family HlyIII PF03006.20 KXL45697.1 - 4.9e-62 209.6 15.2 5.8e-62 209.3 15.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related Ycf66_N PF07444.11 KXL45697.1 - 0.033 14.3 1.1 1.3 9.2 0.1 2.5 2 0 0 2 2 2 0 Ycf66 protein N-terminus DUF962 PF06127.11 KXL45697.1 - 0.6 10.2 4.8 0.18 11.9 1.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF962) TssN PF17555.2 KXL45697.1 - 7.9 5.8 7.0 3.7 6.9 4.4 1.7 1 1 0 1 1 1 0 Type VI secretion system, TssN DUF1765 PF08578.10 KXL45698.1 - 8e-40 136.2 4.2 1.6e-39 135.2 4.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) Coat_F PF07875.12 KXL45698.1 - 0.024 14.8 1.1 1.7 8.9 0.1 2.6 2 0 0 2 2 2 0 Coat F domain Pkinase PF00069.25 KXL45699.1 - 1.5e-51 175.3 0.0 3.9e-51 174.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL45699.1 - 7e-23 81.2 0.8 9e-23 80.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KXL45699.1 - 2.7e-05 24.2 9.0 0.00067 19.7 0.1 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 KXL45699.1 - 0.0073 15.9 0.1 0.048 13.3 0.0 2.2 1 1 0 2 2 2 1 RIO1 family TAF4 PF05236.14 KXL45699.1 - 0.11 12.2 5.5 0.22 11.2 3.2 2.3 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family Choline_kinase PF01633.20 KXL45699.1 - 0.66 9.5 2.4 0.5 9.9 0.2 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase Sugar_tr PF00083.24 KXL45700.1 - 4.2e-86 289.6 26.2 4.9e-86 289.4 26.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL45700.1 - 1.1e-23 83.8 26.0 1.1e-23 83.8 26.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2368 PF10166.9 KXL45700.1 - 0.86 9.2 3.2 1.8 8.2 1.1 2.3 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2368) adh_short_C2 PF13561.6 KXL45701.1 - 8.8e-58 195.6 0.1 1.1e-57 195.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL45701.1 - 1.5e-39 135.5 0.0 1.9e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL45701.1 - 2.4e-12 47.2 0.2 3.4e-12 46.6 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL45701.1 - 0.0016 18.0 0.1 0.0021 17.6 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.18 KXL45702.1 - 1.2e-22 80.2 0.0 1.7e-22 79.7 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 KXL45703.1 - 1.7e-61 207.8 1.9 2.1e-61 207.5 1.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL45703.1 - 4.1e-46 156.9 1.9 5.4e-46 156.5 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL45703.1 - 2.4e-16 60.2 2.1 3.5e-16 59.6 2.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL45703.1 - 0.017 14.6 0.2 0.022 14.2 0.2 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family YAcAr PF10686.9 KXL45703.1 - 0.037 14.0 0.2 0.17 11.9 0.2 2.1 1 1 1 2 2 2 0 YspA, cpYpsA-related SLOG family PRK PF00485.18 KXL45704.1 - 8e-07 29.0 0.0 1.5e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KXL45704.1 - 6.8e-06 26.7 0.3 7.4e-05 23.3 0.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXL45704.1 - 2.8e-05 24.3 0.2 0.0045 17.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 KXL45704.1 - 0.0002 20.5 0.0 0.00031 19.8 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 KXL45704.1 - 0.00025 20.4 0.2 0.00051 19.4 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.6 KXL45704.1 - 0.0015 18.2 0.0 0.0033 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXL45704.1 - 0.0027 18.1 0.2 0.0048 17.3 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 KXL45704.1 - 0.0095 15.4 0.1 0.027 13.9 0.0 1.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA PF00004.29 KXL45704.1 - 0.013 15.9 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KXL45704.1 - 0.014 15.8 0.2 0.2 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KXL45704.1 - 0.017 15.6 0.0 0.028 14.9 0.0 1.3 1 0 0 1 1 1 0 ABC transporter NB-ARC PF00931.22 KXL45704.1 - 0.022 13.9 0.5 0.034 13.3 0.0 1.4 2 0 0 2 2 2 0 NB-ARC domain APS_kinase PF01583.20 KXL45704.1 - 0.025 14.4 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.6 KXL45704.1 - 0.044 14.0 0.0 0.099 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXL45704.1 - 0.053 13.3 0.0 0.094 12.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 KXL45704.1 - 0.079 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KXL45704.1 - 0.081 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KXL45704.1 - 0.087 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase T2SSE PF00437.20 KXL45704.1 - 0.089 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein CoaE PF01121.20 KXL45704.1 - 0.12 12.1 0.2 1.3 8.7 0.0 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_28 PF13521.6 KXL45704.1 - 0.12 12.6 0.2 0.37 11.0 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KXL45704.1 - 0.16 11.7 0.1 0.34 10.6 0.0 1.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KXL45704.1 - 0.17 11.9 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Cytidylate_kin PF02224.18 KXL45704.1 - 0.32 10.7 1.7 0.36 10.5 0.1 1.8 2 0 0 2 2 2 0 Cytidylate kinase ADH_N PF08240.12 KXL45705.1 - 5.3e-31 106.7 0.1 5.3e-31 106.7 0.1 2.7 3 1 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXL45705.1 - 3.3e-20 72.4 0.1 5.8e-20 71.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXL45705.1 - 1.6e-07 31.0 0.1 9.3e-05 22.0 0.0 2.4 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KXL45705.1 - 1.5e-05 26.0 0.0 6.8e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 KXL45705.1 - 0.01 16.5 0.1 0.021 15.5 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 KXL45705.1 - 0.018 14.6 0.2 0.035 13.7 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_11 PF08241.12 KXL45705.1 - 0.032 14.9 0.0 0.072 13.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_72 PF03198.14 KXL45706.1 - 1.5e-123 412.0 1.7 2.1e-123 411.6 1.7 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KXL45706.1 - 8.8e-24 84.0 10.1 2.4e-23 82.6 10.1 1.8 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 KXL45706.1 - 0.033 13.6 0.4 2.6 7.4 0.0 2.4 3 0 0 3 3 3 0 Cellulase (glycosyl hydrolase family 5) FAD_binding_3 PF01494.19 KXL45707.1 - 3.3e-14 52.9 0.4 1.8e-09 37.3 0.0 2.9 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXL45707.1 - 5e-05 23.5 0.0 0.0016 18.6 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain PAS_9 PF13426.7 KXL45708.1 - 1.2e-14 54.4 0.0 4.1e-14 52.7 0.0 2.0 2 0 0 2 2 2 1 PAS domain RGS PF00615.19 KXL45708.1 - 1.2e-14 54.6 0.2 2.4e-14 53.6 0.2 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain PAS PF00989.25 KXL45708.1 - 8.9e-08 32.1 0.0 5.9e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 KXL45708.1 - 2.6e-05 24.4 0.0 0.0007 19.8 0.0 2.7 3 0 0 3 3 3 1 PAS fold PAS_4 PF08448.10 KXL45708.1 - 0.11 12.7 0.0 0.44 10.8 0.0 1.9 2 0 0 2 2 2 0 PAS fold adh_short PF00106.25 KXL45711.1 - 0.0097 15.4 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase CRAL_TRIO PF00650.20 KXL45712.1 - 4.4e-12 46.0 0.1 6.3e-12 45.5 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXL45712.1 - 0.00051 20.2 0.0 0.0011 19.1 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain PGM_PMM_I PF02878.16 KXL45713.1 - 5.8e-17 61.7 1.0 1.9e-07 30.9 0.0 2.6 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KXL45713.1 - 1.6e-10 41.0 1.6 1.2e-09 38.2 0.2 3.1 3 1 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 KXL45713.1 - 0.0064 16.7 0.2 0.021 15.0 0.2 2.0 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KXL45713.1 - 0.012 16.2 1.4 0.46 11.1 0.5 3.5 3 1 0 3 3 3 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II MRP-L28 PF09812.9 KXL45714.1 - 1.2e-08 35.3 0.6 8e-07 29.3 1.0 2.1 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L28 AMP-binding PF00501.28 KXL45715.1 - 2.3e-230 764.5 0.0 4.9e-81 272.5 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 KXL45715.1 - 2.7e-179 596.6 4.8 1.5e-35 122.8 0.0 7.9 6 2 1 7 7 7 7 Condensation domain PP-binding PF00550.25 KXL45715.1 - 2.1e-44 149.7 8.4 6.4e-10 39.2 0.1 7.1 7 0 0 7 7 7 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KXL45715.1 - 1.7e-11 44.9 0.5 1.8e-05 25.7 0.0 4.2 4 0 0 4 4 4 2 AMP-binding enzyme C-terminal domain CompInhib_SCIN PF11546.8 KXL45715.1 - 0.095 12.7 0.6 0.27 11.3 0.6 1.8 1 0 0 1 1 1 0 Staphylococcal complement inhibitor SCIN WES_acyltransf PF03007.16 KXL45715.1 - 0.15 11.8 1.1 19 4.9 0.1 4.0 4 0 0 4 4 4 0 Wax ester synthase-like Acyl-CoA acyltransferase domain ABC_membrane PF00664.23 KXL45716.1 - 3.8e-75 253.1 15.7 5.6e-40 137.7 3.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXL45716.1 - 2.6e-66 222.3 0.0 3.4e-32 111.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KXL45716.1 - 5.8e-16 59.2 1.3 0.00014 21.8 0.0 4.4 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXL45716.1 - 2.7e-14 53.1 3.6 3.1e-05 23.5 0.0 4.6 3 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KXL45716.1 - 5.5e-08 32.9 0.1 0.012 15.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KXL45716.1 - 1.1e-07 31.4 1.6 0.0037 17.0 0.7 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 KXL45716.1 - 2.6e-07 29.8 0.6 0.0071 15.2 0.0 3.5 3 1 0 3 3 3 1 Predicted ATPase of the ABC class AAA_16 PF13191.6 KXL45716.1 - 5.1e-06 27.0 5.0 0.0046 17.4 0.2 3.4 3 2 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 KXL45716.1 - 2.2e-05 24.8 0.1 0.37 11.1 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KXL45716.1 - 0.00018 21.3 1.5 0.45 10.2 0.0 3.2 3 1 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 KXL45716.1 - 0.00026 21.0 1.5 0.28 11.3 0.4 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase Zeta_toxin PF06414.12 KXL45716.1 - 0.00048 19.5 0.0 0.88 8.8 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.6 KXL45716.1 - 0.00083 19.0 0.8 1.3 8.5 0.0 3.9 4 0 0 4 4 4 1 AAA domain AAA_5 PF07728.14 KXL45716.1 - 0.0023 18.0 0.1 4.9 7.2 0.0 3.7 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 KXL45716.1 - 0.0023 18.5 1.4 0.69 10.4 0.9 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KXL45716.1 - 0.0028 18.1 0.0 17 5.8 0.0 4.2 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KXL45716.1 - 0.0034 17.9 0.0 5.5 7.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KXL45716.1 - 0.0042 16.9 0.0 1.8 8.2 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.6 KXL45716.1 - 0.015 15.5 1.5 12 6.2 0.0 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.23 KXL45716.1 - 0.021 14.9 0.7 36 4.4 0.7 3.2 3 0 0 3 3 3 0 Dynamin family AAA_33 PF13671.6 KXL45716.1 - 0.022 14.9 0.5 7.3 6.7 0.2 3.1 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KXL45716.1 - 0.024 13.8 0.0 3.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF87 PF01935.17 KXL45716.1 - 0.031 14.3 3.2 0.82 9.7 2.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Rad17 PF03215.15 KXL45716.1 - 0.042 13.8 0.0 6.9 6.6 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain PRK PF00485.18 KXL45716.1 - 0.05 13.3 0.0 11 5.6 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF3987 PF13148.6 KXL45716.1 - 0.058 12.4 0.1 1.9 7.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_28 PF13521.6 KXL45716.1 - 0.063 13.5 2.2 9.9 6.4 0.6 3.6 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 KXL45716.1 - 0.089 12.0 0.5 22 4.1 0.0 3.1 2 1 0 2 2 2 0 NB-ARC domain Cuticle_1 PF08140.11 KXL45716.1 - 0.09 12.8 1.0 0.94 9.6 0.3 2.6 2 0 0 2 2 2 0 Crustacean cuticle protein repeat AAA_7 PF12775.7 KXL45716.1 - 0.19 11.2 0.3 5.6 6.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region KAP_NTPase PF07693.14 KXL45716.1 - 0.2 10.9 0.0 15 4.7 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain YuiB PF14068.6 KXL45716.1 - 0.24 12.0 2.7 1.6 9.4 0.1 3.4 3 0 0 3 3 3 0 Putative membrane protein AAA_24 PF13479.6 KXL45716.1 - 0.28 10.9 3.4 9.6 5.9 0.0 2.6 3 0 0 3 3 2 0 AAA domain K_oxygenase PF13434.6 KXL45717.1 - 5.7e-106 354.5 0.0 6.6e-106 354.3 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXL45717.1 - 8.9e-06 25.8 0.1 0.00073 19.6 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KXL45717.1 - 9.2e-06 25.1 0.0 9.1e-05 21.8 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXL45717.1 - 2.4e-05 23.7 0.0 0.00077 18.8 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TIMELESS PF04821.14 KXL45718.1 - 4.6e-84 281.9 0.4 4.6e-84 281.9 0.4 1.9 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.13 KXL45718.1 - 9e-28 97.7 3.2 9e-28 97.7 3.2 4.1 2 2 1 3 3 3 1 Timeless protein C terminal region 3HCDH_N PF02737.18 KXL45719.1 - 7.5e-53 179.1 0.1 9.8e-53 178.7 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KXL45719.1 - 3.1e-32 111.0 0.0 6e-32 110.1 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Sacchrp_dh_NADP PF03435.18 KXL45719.1 - 0.00011 22.4 0.3 0.00022 21.5 0.3 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 KXL45719.1 - 0.0035 17.5 0.1 0.0085 16.3 0.1 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_2 PF07992.14 KXL45719.1 - 0.015 14.5 0.1 0.021 14.1 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXL45719.1 - 0.024 13.9 0.6 0.15 11.3 1.7 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KXL45719.1 - 0.042 13.2 0.1 0.062 12.7 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KXL45719.1 - 0.049 13.2 0.0 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 KXL45719.1 - 0.07 13.7 0.1 0.16 12.5 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase WD40 PF00400.32 KXL45722.1 - 0.097 13.6 0.0 5.4 8.1 0.0 2.1 2 0 0 2 2 2 0 WD domain, G-beta repeat adh_short PF00106.25 KXL45723.1 - 4.3e-31 107.9 0.0 8.7e-31 106.9 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL45723.1 - 1.5e-20 73.8 0.0 1.1e-19 71.0 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL45723.1 - 5.8e-07 29.6 0.0 2.7e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXL45723.1 - 0.016 14.7 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Peptidase_C12 PF01088.21 KXL45724.1 - 1.6e-47 162.0 0.0 1.9e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Rad60-SLD PF11976.8 KXL45724.1 - 0.13 12.1 0.0 0.46 10.4 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Sulfate_transp PF00916.20 KXL45725.1 - 6.4e-76 255.6 15.4 6.4e-76 255.6 15.4 1.7 2 1 0 2 2 2 1 Sulfate permease family STAS PF01740.21 KXL45725.1 - 1.1e-12 47.6 0.0 2.1e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KXL45725.1 - 0.0022 18.4 3.2 0.0022 18.4 3.2 4.0 4 0 0 4 4 4 1 Molybdate transporter of MFS superfamily AAA PF00004.29 KXL45726.1 - 7.5e-44 149.4 0.0 1.2e-43 148.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXL45726.1 - 2.7e-15 55.9 0.0 7e-15 54.6 0.0 1.7 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 KXL45726.1 - 1.3e-07 31.7 0.0 3.5e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KXL45726.1 - 2.4e-07 31.0 0.0 4.6e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 KXL45726.1 - 9.8e-07 28.6 2.0 2.8e-06 27.2 2.0 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 KXL45726.1 - 1.6e-06 28.6 0.1 6.4e-05 23.4 0.1 2.9 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KXL45726.1 - 1.7e-05 25.1 0.2 0.0081 16.4 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 KXL45726.1 - 8.7e-05 22.3 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KXL45726.1 - 0.0014 18.8 0.0 0.0027 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KXL45726.1 - 0.0015 17.8 0.0 0.0026 17.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 KXL45726.1 - 0.0023 18.5 0.0 0.02 15.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain Prot_ATP_OB_N PF17758.1 KXL45726.1 - 0.0025 17.4 0.1 0.0083 15.8 0.1 1.9 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain IstB_IS21 PF01695.17 KXL45726.1 - 0.0026 17.5 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 KXL45726.1 - 0.0056 16.5 0.0 0.016 15.1 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KXL45726.1 - 0.0057 16.0 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 KaiC Mg_chelatase PF01078.21 KXL45726.1 - 0.0079 15.6 0.1 0.018 14.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KXL45726.1 - 0.01 16.1 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KXL45726.1 - 0.015 15.3 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 KXL45726.1 - 0.02 14.0 0.0 0.037 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KXL45726.1 - 0.025 14.3 0.0 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 KXL45726.1 - 0.035 13.6 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 KXL45726.1 - 0.036 13.5 0.0 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein HR1 PF02185.16 KXL45726.1 - 0.037 14.2 1.3 0.093 12.9 1.3 1.6 1 0 0 1 1 1 0 Hr1 repeat AAA_24 PF13479.6 KXL45726.1 - 0.038 13.7 0.0 0.077 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXL45726.1 - 0.04 14.3 0.0 0.074 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 KXL45726.1 - 0.042 13.4 0.1 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KXL45726.1 - 0.044 13.8 0.0 0.075 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KXL45726.1 - 0.06 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2072 PF09845.9 KXL45726.1 - 0.072 13.4 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein Zeta_toxin PF06414.12 KXL45726.1 - 0.088 12.1 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 KXL45726.1 - 0.15 12.6 0.1 0.99 9.9 0.0 2.3 2 0 0 2 2 2 0 ABC transporter FTCD_C PF04961.12 KXL45727.1 - 0.0077 16.0 0.4 0.011 15.5 0.4 1.2 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase Na_Ca_ex PF01699.24 KXL45728.1 - 2.4e-19 69.8 38.4 2.5e-12 47.0 14.4 3.8 4 1 0 4 4 4 2 Sodium/calcium exchanger protein YccF PF03733.13 KXL45728.1 - 5e-12 46.3 10.5 5e-12 46.3 10.5 4.4 4 0 0 4 4 4 1 Inner membrane component domain TFIIA PF03153.13 KXL45728.1 - 0.052 13.5 20.2 0.12 12.4 20.2 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TFIIF_alpha PF05793.12 KXL45728.1 - 1.3 7.5 15.5 2.1 6.8 15.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GCIP PF13324.6 KXL45728.1 - 2.9 7.4 5.6 7.7 6.0 5.6 1.7 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Nop14 PF04147.12 KXL45728.1 - 7.4 4.6 20.9 11 4.1 20.9 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4820 PF16091.5 KXL45728.1 - 7.9 5.8 9.5 15 4.8 9.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Tom6 PF17112.5 KXL45729.1 - 1.3e-05 24.6 0.0 1.6e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom6, fungal Bestrophin PF01062.21 KXL45730.1 - 9.7e-36 123.7 0.1 1.8e-35 122.8 0.1 1.3 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Glyco_hydro_65N PF03636.15 KXL45731.1 - 2.6e-36 125.4 0.0 6.4e-36 124.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.15 KXL45731.1 - 3e-30 105.3 5.0 8.7e-29 100.5 1.4 2.7 2 1 1 3 3 3 2 Glycosyl hydrolase family 65 central catalytic domain F5_F8_type_C PF00754.25 KXL45731.1 - 2.9e-06 27.4 0.5 1.2e-05 25.4 0.5 2.1 1 0 0 1 1 1 1 F5/8 type C domain Glyco_hydro_65C PF03633.15 KXL45731.1 - 6.4e-05 22.8 0.0 0.00016 21.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain GDC-P PF02347.16 KXL45733.1 - 6.4e-179 595.3 0.0 3.8e-167 556.5 0.0 2.4 2 1 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 KXL45733.1 - 1.4e-06 27.8 0.5 3.5e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KXL45733.1 - 0.0025 17.2 0.0 0.0046 16.3 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Paf1 PF03985.13 KXL45735.1 - 2.8e-66 224.3 0.0 4.7e-66 223.5 0.0 1.3 1 1 0 1 1 1 1 Paf1 cNMP_binding PF00027.29 KXL45736.1 - 1.4e-27 95.6 0.1 8.5e-18 64.2 0.0 5.1 4 1 0 4 4 4 2 Cyclic nucleotide-binding domain Patatin PF01734.22 KXL45736.1 - 3e-16 60.2 7.0 3e-14 53.7 7.0 3.1 1 1 0 1 1 1 1 Patatin-like phospholipase zf-primase PF09329.11 KXL45737.1 - 7.6e-16 57.7 0.2 2e-15 56.3 0.2 1.8 1 0 0 1 1 1 1 Primase zinc finger SPT6_acidic PF14632.6 KXL45737.1 - 0.0086 16.6 8.7 0.0086 16.6 8.7 3.4 3 0 0 3 3 3 1 Acidic N-terminal SPT6 Ydr279_N PF17745.1 KXL45738.1 - 3.2e-17 62.6 0.0 7.9e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain RNase_H2-Ydr279 PF09468.10 KXL45738.1 - 4.5e-17 62.7 0.0 7.8e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain TTL PF03133.15 KXL45739.1 - 1.4e-51 175.4 0.0 2.1e-51 174.8 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KXL45739.1 - 0.00033 20.0 0.0 0.00064 19.0 0.0 1.4 1 0 0 1 1 1 1 YheC/D like ATP-grasp Brix PF04427.18 KXL45740.1 - 2.2e-45 155.2 0.1 2.8e-45 154.8 0.1 1.1 1 0 0 1 1 1 1 Brix domain CNDH2_C PF16858.5 KXL45740.1 - 0.078 12.8 7.2 0.14 12.0 7.2 1.5 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term CSRNP_N PF16019.5 KXL45740.1 - 0.49 10.3 4.3 1.2 9.0 4.3 1.6 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Kri1 PF05178.12 KXL45740.1 - 0.99 10.0 26.5 0.052 14.1 18.1 2.7 2 1 1 3 3 3 0 KRI1-like family RNA_pol_Rpc4 PF05132.14 KXL45740.1 - 9.1 6.7 6.6 24 5.3 0.0 2.6 2 0 0 2 2 2 0 RNA polymerase III RPC4 DEAD PF00270.29 KXL45741.1 - 3e-47 160.6 0.0 4.5e-47 160.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXL45741.1 - 6.1e-30 103.8 0.0 3.3e-29 101.5 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL45741.1 - 5.4e-05 23.3 0.0 0.00012 22.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KXL45741.1 - 0.00046 19.5 0.0 0.00088 18.5 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Rnf-Nqr PF02508.14 KXL45741.1 - 0.23 11.4 0.3 3 7.8 0.0 2.1 2 0 0 2 2 2 0 Rnf-Nqr subunit, membrane protein DUF3433 PF11915.8 KXL45742.1 - 0.0073 16.7 0.2 0.013 15.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3433) Sugar_tr PF00083.24 KXL45743.1 - 7.4e-85 285.5 26.4 9.2e-85 285.2 26.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL45743.1 - 2.6e-14 52.9 23.9 2.6e-14 52.9 23.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Melibiase_2 PF16499.5 KXL45744.1 - 1.9e-64 217.6 9.4 1.4e-39 135.9 1.8 2.3 2 0 0 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 KXL45744.1 - 1.3e-12 47.6 0.0 3.2e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KXL45744.1 - 4.6e-06 25.8 0.1 1.2e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 Melibiase Raffinose_syn PF05691.12 KXL45744.1 - 0.022 12.6 0.1 0.032 12.0 0.1 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 Surp PF01805.20 KXL45745.1 - 2.7e-05 24.1 0.0 6e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Surp module FAT PF02259.23 KXL45746.1 - 3.5e-123 411.2 1.0 3.5e-123 411.2 1.0 2.3 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 KXL45746.1 - 1.3e-74 251.2 0.2 1.2e-73 248.1 0.1 2.4 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 KXL45746.1 - 8e-65 217.6 8.9 2.2e-60 203.2 0.1 6.1 5 1 1 6 6 6 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 KXL45746.1 - 4e-46 155.5 2.0 1.7e-43 147.1 0.1 3.4 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain FATC PF02260.20 KXL45746.1 - 5.7e-14 51.6 0.3 2.4e-13 49.6 0.2 2.2 2 0 0 2 2 2 1 FATC domain HEAT_2 PF13646.6 KXL45746.1 - 3.4e-12 46.6 13.6 0.018 15.4 0.0 9.3 9 1 0 9 9 9 3 HEAT repeats Cnd1 PF12717.7 KXL45746.1 - 1.4e-09 38.2 6.4 0.29 11.2 0.0 6.7 5 1 2 7 7 7 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KXL45746.1 - 2.9e-08 34.0 14.3 0.01 16.3 0.0 9.9 12 0 0 12 12 10 2 HEAT-like repeat HEAT PF02985.22 KXL45746.1 - 6.3e-07 29.1 19.7 11 6.6 0.0 11.4 13 0 0 13 13 13 1 HEAT repeat Vac14_Fab1_bd PF12755.7 KXL45746.1 - 1.4e-06 28.8 5.3 5.6 7.6 0.0 8.0 8 2 2 10 10 10 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KXL45746.1 - 6.1e-05 22.7 2.9 0.61 9.6 0.0 5.2 3 2 3 6 6 6 2 CLASP N terminal Adaptin_N PF01602.20 KXL45746.1 - 6.8e-05 21.6 11.6 0.043 12.4 0.6 5.2 4 2 0 4 4 4 2 Adaptin N terminal region Tti2 PF10521.9 KXL45746.1 - 0.0002 21.0 0.2 0.078 12.5 0.0 3.3 3 1 0 3 3 3 1 Tti2 family ParcG PF10274.9 KXL45746.1 - 0.14 12.2 14.3 0.37 10.9 0.1 5.3 6 0 0 6 6 6 0 Parkin co-regulated protein SLAC1 PF03595.17 KXL45747.1 - 2.4e-78 263.6 50.8 2.8e-78 263.4 50.8 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel adh_short PF00106.25 KXL45748.1 - 2.4e-31 108.7 1.3 9.9e-20 70.8 0.0 3.1 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXL45748.1 - 4.1e-23 82.2 1.8 2.4e-13 50.2 0.0 2.8 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL45748.1 - 0.017 15.0 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 KR domain Sad1_UNC PF07738.13 KXL45749.1 - 3.7e-09 36.7 0.0 7.7e-05 22.7 0.0 2.4 1 1 1 2 2 2 2 Sad1 / UNC-like C-terminal DNA_pol_delta_4 PF04081.13 KXL45750.1 - 8.3e-39 132.9 0.5 8.3e-39 132.9 0.5 2.1 2 0 0 2 2 2 1 DNA polymerase delta, subunit 4 CEND1 PF15677.5 KXL45750.1 - 0.056 14.0 1.7 0.097 13.2 1.7 1.4 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 DcpS_C PF11969.8 KXL45751.1 - 4.8e-30 104.4 0.4 7.5e-30 103.7 0.4 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 KXL45751.1 - 2.3e-26 92.6 0.0 4.3e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal RhoGEF PF00621.20 KXL45752.1 - 2.5e-21 76.8 0.0 8.4e-21 75.0 0.0 1.9 1 0 0 1 1 1 1 RhoGEF domain DUF3507 PF12015.8 KXL45752.1 - 2.3e-05 24.2 0.0 4.9e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) Nod1 PF17114.5 KXL45752.1 - 4.2e-05 23.7 0.0 0.00017 21.8 0.0 2.0 3 0 0 3 3 3 1 Gef2-related medial cortical node protein Nod1 Fib_alpha PF08702.10 KXL45752.1 - 0.018 15.3 1.5 0.14 12.4 0.3 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 KXL45752.1 - 0.071 12.5 7.5 0.18 11.2 3.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) TSC22 PF01166.18 KXL45752.1 - 0.23 11.8 1.4 0.8 10.1 0.5 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF848 PF05852.11 KXL45752.1 - 0.49 10.5 3.9 22 5.1 0.5 3.3 2 1 1 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) Med9 PF07544.13 KXL45752.1 - 0.88 9.7 5.1 1.5 9.0 0.0 3.6 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF4201 PF13870.6 KXL45752.1 - 3.8 7.2 7.9 1.2 8.8 3.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) SOGA PF11365.8 KXL45752.1 - 4.9 8.3 11.1 0.49 11.6 3.2 3.2 3 0 0 3 3 3 0 Protein SOGA ATG16 PF08614.11 KXL45752.1 - 4.9 7.3 21.5 0.91 9.7 1.1 4.0 2 1 0 3 3 3 0 Autophagy protein 16 (ATG16) PRKG1_interact PF15898.5 KXL45752.1 - 9.8 7.1 9.9 64 4.5 0.1 3.6 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain Dcc1 PF09724.9 KXL45753.1 - 2.4e-30 106.0 0.0 3e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Auxin_repressed PF05564.12 KXL45753.1 - 0.0027 18.4 0.7 2.6 8.8 0.1 2.3 2 0 0 2 2 2 2 Dormancy/auxin associated protein IF-2B PF01008.17 KXL45754.1 - 1.9e-47 161.8 0.0 2.2e-47 161.6 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Cpn60_TCP1 PF00118.24 KXL45755.1 - 1.4e-151 505.5 7.6 1.6e-151 505.3 7.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Tautomerase_3 PF14832.6 KXL45756.1 - 8e-09 35.8 0.0 2.6e-08 34.2 0.0 1.8 2 1 0 2 2 2 1 Putative oxalocrotonate tautomerase enzyme Synaptobrevin PF00957.21 KXL45757.1 - 1.5e-31 108.1 0.0 1.9e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KXL45757.1 - 7.2e-25 86.9 0.0 1.1e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Ion_trans PF00520.31 KXL45759.1 - 2.4e-10 40.1 24.3 3.8e-10 39.4 24.3 1.3 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KXL45759.1 - 0.0014 17.4 18.4 0.067 11.9 18.4 2.2 1 1 0 1 1 1 1 Polycystin cation channel eIF-1a PF01176.19 KXL45760.1 - 2e-17 62.7 0.0 2.8e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ALG3 PF05208.13 KXL45761.1 - 1.5e-142 475.3 12.3 1.8e-142 475.1 12.3 1.0 1 0 0 1 1 1 1 ALG3 protein DUF2070 PF09843.9 KXL45761.1 - 0.3 9.3 11.9 0.48 8.6 11.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) adh_short PF00106.25 KXL45762.1 - 2e-33 115.5 0.0 1e-25 90.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXL45762.1 - 8e-21 74.7 0.0 2.5e-15 56.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL45762.1 - 6.5e-11 42.5 0.0 1.2e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXL45762.1 - 0.014 15.3 0.0 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXL45762.1 - 0.056 12.6 0.2 0.17 11.0 0.2 1.8 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KXL45762.1 - 0.073 12.2 0.0 0.19 10.9 0.0 1.7 1 1 0 1 1 1 0 Male sterility protein PIN_5 PF08745.11 KXL45764.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 PINc domain ribonuclease NUC173 PF08161.12 KXL45764.1 - 0.017 14.8 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 NUC173 domain Exo_endo_phos_2 PF14529.6 KXL45765.1 - 1.5e-05 24.8 0.0 1.5e-05 24.8 0.0 1.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Asp PF00026.23 KXL45767.1 - 6.7e-07 29.0 0.0 7e-07 29.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KXL45767.1 - 0.021 14.6 0.0 0.021 14.6 0.0 1.1 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Carboxyl_trans PF01039.22 KXL45767.1 - 0.13 10.9 0.0 0.13 10.9 0.0 1.0 1 0 0 1 1 1 0 Carboxyl transferase domain DUF1993 PF09351.10 KXL45768.1 - 3.8e-05 23.9 0.0 4.3e-05 23.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) DUF1993 PF09351.10 KXL45769.1 - 4.4e-18 65.9 0.0 4.7e-18 65.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) USP7_ICP0_bdg PF12436.8 KXL45769.1 - 0.077 12.3 0.0 0.079 12.3 0.0 1.0 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 RNase_H PF00075.24 KXL45770.1 - 8.7e-11 42.2 0.1 7.1e-05 23.0 0.1 2.4 1 1 1 2 2 2 2 RNase H RVT_3 PF13456.6 KXL45770.1 - 0.027 14.3 0.0 0.06 13.2 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like Met_10 PF02475.16 KXL45772.1 - 4e-07 30.0 0.0 5.2e-06 26.3 0.0 2.3 2 1 0 2 2 2 1 Met-10+ like-protein EF-hand_6 PF13405.6 KXL45773.1 - 4.7e-07 29.2 0.3 0.049 13.6 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KXL45773.1 - 1.5e-05 24.2 0.0 5.1e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KXL45773.1 - 4.9e-05 23.7 0.2 0.0001 22.7 0.2 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KXL45773.1 - 0.018 14.5 0.0 0.042 13.4 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.6 KXL45773.1 - 0.09 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair NmrA PF05368.13 KXL45775.1 - 1.9e-47 161.8 0.0 2.4e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXL45775.1 - 2.9e-15 56.6 0.0 5.3e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXL45775.1 - 3.4e-05 23.0 0.0 0.00027 20.1 0.0 1.9 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXL45775.1 - 5.7e-05 22.7 0.0 0.00016 21.2 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXL45775.1 - 0.0035 17.3 0.1 0.0059 16.5 0.1 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KXL45775.1 - 0.0093 15.4 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KXL45775.1 - 0.018 14.5 0.1 0.029 13.8 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase TrkA_N PF02254.18 KXL45775.1 - 0.055 13.7 0.0 0.099 12.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_4 PF07993.12 KXL45775.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Calpain_III PF01067.22 KXL45775.1 - 0.18 12.0 0.0 0.34 11.2 0.0 1.3 1 0 0 1 1 1 0 Calpain large subunit, domain III Caerin_1 PF07440.12 KXL45775.1 - 2.8 8.1 3.9 0.72 10.0 0.2 1.9 2 0 0 2 2 2 0 Caerin 1 protein Abhydrolase_3 PF07859.13 KXL45776.1 - 5.8e-30 104.7 0.0 7.6e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXL45776.1 - 0.18 10.6 0.0 0.25 10.2 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family GDP_Man_Dehyd PF16363.5 KXL45777.1 - 4.2e-54 184.2 0.0 6e-54 183.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KXL45777.1 - 1e-48 165.9 0.0 1.3e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXL45777.1 - 4.4e-16 58.7 0.0 7.1e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KXL45777.1 - 2e-15 56.7 0.0 9.8e-14 51.2 0.0 2.7 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KXL45777.1 - 3.3e-10 39.6 0.0 4.5e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 KXL45777.1 - 1.1e-09 38.1 0.0 1.9e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL45777.1 - 5.8e-08 32.9 0.0 1.1e-07 31.9 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 KXL45777.1 - 7.2e-06 25.4 0.0 0.00039 19.7 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein adh_short_C2 PF13561.6 KXL45777.1 - 2.4e-05 24.0 0.0 4.1e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KXL45777.1 - 0.00043 20.2 0.0 0.00072 19.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXL45777.1 - 0.024 14.2 0.0 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family UDPG_MGDP_dh_N PF03721.14 KXL45777.1 - 0.13 11.8 0.1 0.24 10.9 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Peptidase_C12 PF01088.21 KXL45778.1 - 1.2e-56 191.9 0.0 1.3e-56 191.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 FAD_binding_3 PF01494.19 KXL45779.1 - 4.3e-33 115.0 0.1 6.3e-33 114.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain MIF4G PF02854.19 KXL45781.1 - 2.4e-46 158.1 0.0 4.5e-46 157.1 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 KXL45781.1 - 2.9e-19 69.0 0.5 7.3e-19 67.7 0.5 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 NAM-associated PF14303.6 KXL45781.1 - 0.015 16.0 0.0 0.015 16.0 0.0 5.9 4 1 2 6 6 6 0 No apical meristem-associated C-terminal domain Homeodomain PF00046.29 KXL45783.1 - 7.9e-18 64.1 3.0 1.4e-17 63.3 3.0 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KXL45783.1 - 0.003 17.4 0.1 0.0071 16.2 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain efThoc1 PF11957.8 KXL45784.1 - 6e-117 391.3 0.1 7.8e-117 390.9 0.1 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Swi3 PF07962.12 KXL45785.1 - 2.6e-30 104.3 1.0 4.1e-30 103.6 1.0 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 ECH_1 PF00378.20 KXL45786.1 - 3.2e-76 256.0 0.0 3.6e-76 255.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXL45786.1 - 4.8e-35 121.6 0.1 7.2e-33 114.5 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Rer1 PF03248.13 KXL45787.1 - 6.3e-75 250.6 4.1 7.2e-75 250.4 4.1 1.0 1 0 0 1 1 1 1 Rer1 family DUF2157 PF09925.9 KXL45787.1 - 2.6 7.8 9.1 11 5.8 9.1 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) AFG1_ATPase PF03969.16 KXL45788.1 - 2.3e-62 211.0 0.3 1.3e-29 103.2 0.0 5.0 3 2 2 5 5 5 5 AFG1-like ATPase AAA_5 PF07728.14 KXL45788.1 - 7.5e-06 26.0 0.0 1.9e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXL45788.1 - 0.00024 21.5 0.2 0.0019 18.6 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA PF00004.29 KXL45788.1 - 0.0015 18.9 0.0 0.0034 17.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXL45788.1 - 0.0019 18.5 0.0 0.0038 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KXL45788.1 - 0.054 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 KXL45788.1 - 0.14 11.5 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 KXL45788.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 KXL45788.1 - 0.2 11.6 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE G-patch PF01585.23 KXL45789.1 - 1.9e-10 40.5 0.4 5.2e-10 39.1 0.3 1.8 2 0 0 2 2 2 1 G-patch domain ABC2_membrane PF01061.24 KXL45790.1 - 2.1e-91 305.1 60.4 1.4e-46 158.6 26.2 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KXL45790.1 - 5.6e-37 127.3 0.0 6.1e-17 62.4 0.0 3.3 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 KXL45790.1 - 8.6e-34 115.3 3.3 4.6e-32 109.8 0.5 4.0 5 0 0 5 5 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KXL45790.1 - 5.5e-19 68.6 0.1 1.2e-18 67.5 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 KXL45790.1 - 1.3e-06 28.1 0.0 1.7e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXL45790.1 - 4.1e-06 27.0 0.2 0.0097 16.1 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KXL45790.1 - 1.6e-05 25.3 0.0 0.021 15.2 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KXL45790.1 - 1.7e-05 24.8 0.3 0.0021 18.0 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 KXL45790.1 - 0.0001 22.8 0.0 0.034 14.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KXL45790.1 - 0.00032 21.2 0.7 0.052 14.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KXL45790.1 - 0.00065 19.4 1.9 0.03 14.1 0.2 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KXL45790.1 - 0.00083 19.2 0.0 1.8 8.3 0.0 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KXL45790.1 - 0.0026 17.5 0.3 0.35 10.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXL45790.1 - 0.006 16.9 0.3 2.4 8.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KXL45790.1 - 0.022 14.2 0.0 1.7 8.0 0.0 3.2 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain cobW PF02492.19 KXL45790.1 - 0.035 13.7 1.6 0.56 9.8 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 KXL45790.1 - 0.036 13.8 0.3 6 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 KXL45790.1 - 0.079 12.9 0.1 0.71 9.8 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_28 PF13521.6 KXL45790.1 - 0.12 12.6 0.3 4.1 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KXL45790.1 - 0.13 12.2 1.2 2.8 7.8 0.3 2.5 2 0 0 2 2 2 0 NACHT domain Shugoshin_N PF07558.11 KXL45791.1 - 5.7e-18 64.5 6.8 1e-17 63.7 6.8 1.4 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 KXL45791.1 - 1.4e-11 44.0 4.7 1.4e-11 44.0 4.7 2.6 2 0 0 2 2 2 1 Shugoshin C terminus KASH_CCD PF14662.6 KXL45791.1 - 0.017 15.0 0.5 0.033 14.0 0.5 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH CCDC85 PF10226.9 KXL45791.1 - 0.024 14.3 2.6 0.083 12.6 2.4 2.0 1 1 0 1 1 1 0 CCDC85 family Mod_r PF07200.13 KXL45791.1 - 0.055 13.6 0.3 0.1 12.7 0.3 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein GIT_CC PF16559.5 KXL45791.1 - 0.11 12.3 0.4 0.29 11.0 0.4 1.7 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DASH_Dad2 PF08654.10 KXL45792.1 - 1.4e-31 108.8 0.4 2.2e-31 108.2 0.4 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad2 DASH_Duo1 PF08651.10 KXL45792.1 - 0.011 15.5 0.1 0.018 14.8 0.1 1.3 1 0 0 1 1 1 0 DASH complex subunit Duo1 HAUS2 PF15003.6 KXL45792.1 - 0.019 14.7 0.3 0.027 14.2 0.3 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 IFT20 PF14931.6 KXL45792.1 - 0.1 12.8 2.9 0.22 11.7 3.1 1.5 1 1 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 RapH_N PF18801.1 KXL45792.1 - 0.13 12.4 0.1 0.79 9.9 0.0 2.0 2 0 0 2 2 2 0 response regulator aspartate phosphatase H, N terminal PPI_Ypi1 PF07491.11 KXL45793.1 - 1.3e-24 85.8 2.1 2.7e-24 84.8 2.1 1.6 1 0 0 1 1 1 1 Protein phosphatase inhibitor YL1 PF05764.13 KXL45793.1 - 0.027 14.6 1.2 0.031 14.4 1.2 1.1 1 0 0 1 1 1 0 YL1 nuclear protein CRM1_C PF08767.11 KXL45794.1 - 4.6e-133 443.3 3.5 4.6e-133 443.3 3.5 2.7 2 1 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 KXL45794.1 - 4.5e-39 133.9 8.4 5.7e-39 133.5 2.3 4.0 4 0 0 4 4 4 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KXL45794.1 - 1.1e-33 114.7 4.4 4.9e-33 112.6 2.8 2.8 3 0 0 3 3 3 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KXL45794.1 - 6e-30 103.1 2.3 1.3e-29 102.0 0.9 2.4 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KXL45794.1 - 3.2e-20 71.3 2.9 8.7e-20 70.0 2.9 1.8 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KXL45794.1 - 6.4e-13 48.4 0.1 3.3e-12 46.2 0.1 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.8 KXL45794.1 - 0.0041 17.1 2.5 0.18 11.7 0.0 4.4 3 1 1 4 4 4 1 Domain of unknown function (DUF3385) BID PF06393.11 KXL45794.1 - 0.014 14.9 0.3 0.045 13.3 0.3 1.9 1 0 0 1 1 1 0 BH3 interacting domain (BID) Hemocyanin_M PF00372.19 KXL45794.1 - 0.046 12.9 0.5 0.29 10.3 0.1 2.2 2 0 0 2 2 2 0 Hemocyanin, copper containing domain HD_assoc PF13286.6 KXL45794.1 - 0.055 14.0 0.3 43 4.7 0.1 3.8 3 0 0 3 3 2 0 Phosphohydrolase-associated domain Pre-PUA PF17832.1 KXL45794.1 - 0.079 13.6 0.3 2.2 9.0 0.0 3.3 3 0 0 3 3 3 0 Pre-PUA-like domain Vac14_Fab1_bd PF12755.7 KXL45794.1 - 0.9 10.2 3.5 21 5.8 0.0 4.5 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region YCII PF03795.14 KXL45795.1 - 3.3e-09 37.0 0.0 4.7e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Amidohydro_1 PF01979.20 KXL45796.1 - 3.6e-15 56.1 0.0 4.2e-15 55.9 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXL45796.1 - 4.8e-07 29.6 0.0 4.8e-07 29.6 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family SM-ATX PF14438.6 KXL45796.1 - 0.13 12.4 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Sugar_tr PF00083.24 KXL45797.1 - 3e-80 270.3 20.9 3.5e-80 270.1 20.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL45797.1 - 6.3e-19 68.1 46.1 2.3e-16 59.7 29.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KXL45797.1 - 1.6e-07 31.0 2.4 4.1e-07 29.6 2.4 1.7 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB TPT PF03151.16 KXL45798.1 - 4.4e-09 36.1 5.9 4.9e-09 36.0 5.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family NAD_binding_8 PF13450.6 KXL45800.1 - 9e-08 32.2 0.0 2.8e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KXL45800.1 - 1.6e-07 31.0 0.0 2.1e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 KXL45800.1 - 0.01 15.1 0.1 0.019 14.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KXL45800.1 - 0.02 14.1 0.1 0.033 13.4 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXL45800.1 - 0.021 14.1 0.1 0.057 12.7 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXL45800.1 - 0.025 13.8 0.1 0.042 13.1 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 KXL45800.1 - 0.031 14.5 0.0 0.48 10.7 0.0 2.5 3 0 0 3 3 3 0 TrkA-N domain FAD_oxidored PF12831.7 KXL45800.1 - 0.04 13.3 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.24 KXL45800.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXL45800.1 - 0.18 10.8 0.2 0.3 10.1 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Cellulase PF00150.18 KXL45801.1 - 3.2e-18 66.2 4.6 6.8e-18 65.1 4.6 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SET PF00856.28 KXL45802.1 - 0.12 12.8 0.0 1.7 9.0 0.0 2.3 2 0 0 2 2 2 0 SET domain MCM PF00493.23 KXL45803.1 - 3.6e-101 337.0 0.0 5.5e-101 336.3 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KXL45803.1 - 2.4e-38 130.8 0.0 4.3e-38 130.0 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 KXL45803.1 - 6.3e-30 104.5 23.4 6.3e-30 104.5 23.4 1.8 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 KXL45803.1 - 6.9e-26 90.5 0.5 2.5e-25 88.7 0.5 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KXL45803.1 - 1.2e-14 54.7 0.0 4.2e-13 49.8 0.0 2.5 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KXL45803.1 - 8.9e-09 35.0 0.0 2.5e-06 27.0 0.0 2.5 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KXL45803.1 - 1.2e-06 28.5 0.0 2.7e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KXL45803.1 - 0.00014 21.8 0.1 0.0011 18.8 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KXL45803.1 - 0.00075 19.2 0.1 0.0068 16.1 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_30 PF13604.6 KXL45803.1 - 0.1 12.3 1.1 0.25 11.0 0.3 2.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KXL45803.1 - 0.17 12.3 0.1 0.51 10.8 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-UBR PF02207.20 KXL45804.1 - 7.2e-14 51.7 4.9 7.2e-14 51.7 4.9 3.7 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) Acetyltransf_3 PF13302.7 KXL45805.1 - 1.6e-26 93.6 0.0 1.9e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXL45805.1 - 4.6e-07 30.1 0.0 1e-06 29.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXL45805.1 - 0.1 13.1 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KXL45805.1 - 0.23 11.6 0.0 0.44 10.7 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain 2OG-FeII_Oxy_2 PF13532.6 KXL45806.1 - 4.9e-36 124.8 0.0 6.9e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 KXL45806.1 - 0.00044 20.3 4.4 0.001 19.1 4.4 1.6 1 0 0 1 1 1 1 GRF zinc finger ATG7_N PF16420.5 KXL45807.1 - 4.5e-110 368.0 0.0 6.3e-110 367.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 KXL45807.1 - 1.1e-38 133.1 0.0 1.8e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 ThiF family dCMP_cyt_deam_1 PF00383.23 KXL45808.1 - 9.4e-27 92.9 2.5 1.5e-26 92.2 2.5 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXL45808.1 - 6.4e-10 38.9 0.2 1.1e-09 38.2 0.2 1.3 1 0 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 KXL45808.1 - 0.0043 17.6 0.0 0.01 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain RabGAP-TBC PF00566.18 KXL45809.1 - 9.8e-52 175.7 0.0 1.7e-51 175.0 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RRM_1 PF00076.22 KXL45812.1 - 1.9e-32 110.9 0.6 2.9e-16 59.0 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXL45812.1 - 6.6e-12 45.4 0.1 0.00016 21.7 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KXL45812.1 - 0.0023 17.9 0.0 1.9 8.6 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KXL45812.1 - 0.029 14.4 0.0 1.8 8.6 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif NTP_transferase PF00483.23 KXL45812.1 - 0.04 13.5 0.2 0.081 12.5 0.0 1.5 2 0 0 2 2 2 0 Nucleotidyl transferase XPC-binding PF09280.11 KXL45812.1 - 0.25 11.1 9.2 1.1 9.1 9.2 1.9 1 1 0 1 1 1 0 XPC-binding domain Band_7 PF01145.25 KXL45813.1 - 9.6e-24 84.4 3.3 1.6e-23 83.6 3.3 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family Lectin_leg-like PF03388.13 KXL45814.1 - 3.3e-31 108.4 0.0 5e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Baculo_PEP_C PF04513.12 KXL45814.1 - 0.0019 18.3 0.1 0.0036 17.3 0.1 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus ABC_tran_CTD PF16326.5 KXL45814.1 - 0.0082 16.4 0.0 0.93 9.8 0.0 2.3 2 0 0 2 2 2 1 ABC transporter C-terminal domain Occludin_ELL PF07303.13 KXL45814.1 - 0.026 15.3 0.1 0.11 13.2 0.1 1.9 1 1 0 1 1 1 0 Occludin homology domain Spc7 PF08317.11 KXL45814.1 - 0.05 12.5 0.0 0.074 11.9 0.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Flu_B_NS1 PF02942.14 KXL45814.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Influenza B non-structural protein (NS1) Prefoldin_2 PF01920.20 KXL45814.1 - 0.2 11.6 0.5 16 5.5 0.0 2.3 1 1 1 2 2 2 0 Prefoldin subunit NPV_P10 PF05531.12 KXL45814.1 - 0.25 11.9 0.6 25 5.4 0.1 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein HSBP1 PF06825.12 KXL45814.1 - 0.86 9.5 3.6 23 4.9 0.2 2.8 3 0 0 3 3 3 0 Heat shock factor binding protein 1 Exo_endo_phos PF03372.23 KXL45816.1 - 3.2e-09 36.7 0.0 6.5e-09 35.6 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family XPG_I PF00867.18 KXL45817.1 - 2.7e-32 111.0 2.7 1.6e-31 108.5 0.0 2.6 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 KXL45817.1 - 1.9e-29 102.1 0.0 1.9e-29 102.1 0.0 2.1 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.20 KXL45817.1 - 1.5e-06 28.7 1.2 6.1e-06 26.8 0.0 2.5 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 KXL45817.1 - 0.052 14.2 0.0 0.16 12.6 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain Fe_dep_repr_C PF02742.15 KXL45817.1 - 0.13 12.4 2.6 19 5.5 0.0 3.5 4 0 0 4 4 4 0 Iron dependent repressor, metal binding and dimerisation domain Acyl-CoA_dh_1 PF00441.24 KXL45818.1 - 4.2e-24 85.5 0.5 6.8e-24 84.8 0.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXL45818.1 - 4.9e-23 82.0 0.0 1e-22 80.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KXL45818.1 - 2.4e-16 59.7 0.0 4.6e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXL45818.1 - 4.8e-07 30.1 0.7 9.3e-07 29.2 0.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PH_10 PF15411.6 KXL45819.1 - 8.3e-26 90.7 0.1 1.4e-25 89.9 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 KXL45819.1 - 2.3e-14 54.0 0.0 4e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KXL45819.1 - 9.3e-10 38.6 0.1 3e-09 37.0 0.1 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 KXL45819.1 - 0.0053 17.1 1.3 0.0094 16.3 1.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KXL45819.1 - 0.0053 16.7 1.7 0.0089 16.0 1.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING-like PF08746.11 KXL45819.1 - 0.012 15.9 1.8 0.021 15.1 1.8 1.4 1 0 0 1 1 1 0 RING-like domain zf-rbx1 PF12678.7 KXL45819.1 - 0.019 15.2 1.0 0.034 14.4 1.0 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KXL45819.1 - 0.029 14.2 1.7 0.056 13.3 1.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXL45819.1 - 0.033 14.1 1.9 0.063 13.2 1.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KXL45819.1 - 0.063 12.9 3.2 0.037 13.7 0.9 1.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 KXL45819.1 - 0.12 12.3 0.6 0.2 11.6 0.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1147 PF06615.11 KXL45819.1 - 0.12 12.4 0.2 0.28 11.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) Reo_sigmaC PF04582.12 KXL45819.1 - 0.24 11.7 0.7 7.5 6.8 0.3 2.4 2 0 0 2 2 2 0 Reovirus sigma C capsid protein C-terminal domain SOCS_box PF07525.16 KXL45820.1 - 0.21 11.9 1.9 0.47 10.9 1.9 1.5 1 0 0 1 1 1 0 SOCS box adh_short PF00106.25 KXL45821.1 - 1.6e-37 128.8 0.0 1.9e-37 128.6 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL45821.1 - 6.7e-27 94.6 0.1 7.9e-27 94.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL45821.1 - 1.4e-11 44.7 0.3 1.8e-11 44.3 0.3 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXL45821.1 - 0.022 14.7 0.1 0.048 13.6 0.1 1.8 1 1 0 1 1 1 0 NAD(P)H-binding Eno-Rase_NADH_b PF12242.8 KXL45821.1 - 0.043 13.6 1.9 0.23 11.2 0.0 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.10 KXL45821.1 - 0.047 13.1 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 KXL45821.1 - 0.084 12.0 0.0 0.22 10.6 0.0 1.7 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 KXL45821.1 - 0.13 11.7 0.0 2.9 7.3 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DAO PF01266.24 KXL45822.1 - 7.9e-51 173.7 0.8 9.2e-51 173.5 0.8 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXL45822.1 - 7e-05 22.2 0.0 0.011 14.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXL45822.1 - 0.0017 18.9 0.0 0.024 15.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXL45822.1 - 0.0021 18.3 0.2 0.0052 17.0 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain MCRA PF06100.11 KXL45822.1 - 0.003 16.4 0.1 0.0042 15.9 0.1 1.1 1 0 0 1 1 1 1 MCRA family ApbA PF02558.16 KXL45822.1 - 0.026 14.1 0.1 0.063 12.9 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 KXL45822.1 - 0.049 13.9 0.1 0.18 12.1 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain ThiF PF00899.21 KXL45822.1 - 0.09 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 ThiF family PPR_2 PF13041.6 KXL45824.1 - 1.8e-16 60.1 0.2 8e-14 51.6 0.0 4.4 5 0 0 5 5 5 1 PPR repeat family PPR_3 PF13812.6 KXL45824.1 - 0.0001 22.3 0.0 1.5 8.9 0.0 4.5 4 1 1 5 5 5 2 Pentatricopeptide repeat domain PPR PF01535.20 KXL45824.1 - 0.00011 22.2 0.1 0.024 14.9 0.0 3.8 4 0 0 4 4 4 1 PPR repeat Kinesin PF00225.23 KXL45825.1 - 5.1e-60 203.1 0.0 8e-60 202.5 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXL45825.1 - 7.2e-10 39.0 0.1 2.3e-07 30.9 0.0 2.7 2 0 0 2 2 2 2 Microtubule binding KIAA1430 PF13879.6 KXL45825.1 - 0.025 15.3 0.5 0.089 13.6 0.5 1.9 1 0 0 1 1 1 0 KIAA1430 homologue TSC22 PF01166.18 KXL45825.1 - 0.028 14.7 6.8 0.031 14.6 0.8 2.9 2 0 0 2 2 2 0 TSC-22/dip/bun family LprI PF07007.12 KXL45825.1 - 0.14 12.8 6.8 0.084 13.5 2.7 2.4 2 0 0 2 2 2 0 Lysozyme inhibitor LprI E2F_CC-MB PF16421.5 KXL45825.1 - 5.8 7.3 7.1 9.8 6.6 0.4 3.0 3 0 0 3 3 3 0 E2F transcription factor CC-MB domain DUF87 PF01935.17 KXL45825.1 - 8.2 6.4 5.9 5.7 7.0 0.7 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain Got1 PF04178.12 KXL45826.1 - 3.1e-14 53.3 14.4 3.7e-14 53.1 14.4 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Peptidase_C32 PF05411.12 KXL45826.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Equine arteritis virus putative proteinase Peptidase_A24 PF01478.18 KXL45826.1 - 1.6 9.2 10.0 0.4 11.1 3.0 2.1 2 0 0 2 2 2 0 Type IV leader peptidase family DUF373 PF04123.13 KXL45826.1 - 2.2 7.6 5.3 0.64 9.4 1.7 1.6 1 1 0 2 2 2 0 Domain of unknown function (DUF373) DAHP_synth_1 PF00793.20 KXL45827.1 - 2.8e-101 338.0 0.0 3.5e-101 337.7 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family MFS_1 PF07690.16 KXL45828.1 - 0.012 14.5 0.0 0.021 13.8 0.0 1.3 1 0 0 1 1 1 0 Major Facilitator Superfamily Sod_Cu PF00080.20 KXL45829.1 - 2.3e-13 50.5 0.0 3.8e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.26 KXL45829.1 - 4.4e-11 43.1 0.0 7.9e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain Ribosomal_L13 PF00572.18 KXL45830.1 - 7.1e-49 165.2 0.0 1.1e-48 164.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 Uricase PF01014.18 KXL45831.1 - 1.3e-79 264.9 0.2 9.5e-42 142.4 0.1 2.0 2 0 0 2 2 2 2 Uricase RICTOR_N PF14664.6 KXL45832.1 - 1.9e-121 405.6 1.3 9.6e-121 403.3 0.1 2.6 2 1 1 3 3 3 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 KXL45832.1 - 1e-39 134.5 0.8 1.2e-36 124.7 0.2 4.8 3 1 2 5 5 5 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 KXL45832.1 - 1.1e-38 131.9 0.1 8.5e-36 122.6 0.0 3.6 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 KXL45832.1 - 2.6e-29 101.3 2.8 1.8e-26 92.1 0.3 4.2 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 KXL45832.1 - 2.1e-12 46.9 10.4 6.3e-12 45.4 10.4 1.8 1 0 0 1 1 1 1 Hr1 repeat HEAT_EZ PF13513.6 KXL45832.1 - 0.025 15.1 0.2 14 6.3 0.0 4.2 3 1 1 4 4 4 0 HEAT-like repeat Methyltransf_2 PF00891.18 KXL45832.1 - 0.084 12.2 0.0 0.21 10.9 0.0 1.6 1 1 0 1 1 1 0 O-methyltransferase domain ADH_N PF08240.12 KXL45833.1 - 1.9e-07 30.9 0.0 4.6e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXL45833.1 - 0.00025 21.0 0.0 0.00053 20.0 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KXL45833.1 - 0.06 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Aminotran_5 PF00266.19 KXL45834.1 - 1.4e-09 37.4 0.0 1.2e-06 27.7 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V MFS_1 PF07690.16 KXL45835.1 - 3.2e-23 82.2 22.2 3.2e-23 82.2 22.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3295 PF11702.8 KXL45836.1 - 0.19 11.0 7.7 0.62 9.3 1.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3295) ATG22 PF11700.8 KXL45837.1 - 1e-132 443.2 27.8 1.2e-132 443.0 27.8 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KXL45837.1 - 7.6e-13 48.1 30.0 6.6e-09 35.2 2.1 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily ATP-grasp_2 PF08442.10 KXL45838.1 - 3.9e-77 258.4 0.4 3.9e-77 258.4 0.4 1.7 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 KXL45838.1 - 9.8e-27 93.7 0.3 1.9e-26 92.7 0.3 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KXL45838.1 - 1.7e-08 34.2 0.4 6.9e-08 32.2 0.4 2.0 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KXL45838.1 - 0.0094 15.7 0.6 0.28 10.9 0.1 2.5 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Bromo_TP_like PF17027.5 KXL45838.1 - 0.066 13.4 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Histone-fold protein Pkinase PF00069.25 KXL45839.1 - 3.4e-61 206.9 0.0 6e-61 206.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL45839.1 - 1.1e-35 123.2 0.0 2.2e-35 122.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 KXL45839.1 - 7.1e-31 106.1 15.3 6.7e-16 58.2 2.9 2.6 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 KXL45839.1 - 2.3e-20 72.2 29.3 2.7e-12 46.4 8.9 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 KXL45839.1 - 1.9e-13 50.9 0.2 1.2e-12 48.3 0.3 2.5 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 KXL45839.1 - 0.034 13.5 0.0 0.089 12.1 0.0 1.6 2 0 0 2 2 2 0 Kinase-like FTA2 PF13095.6 KXL45839.1 - 0.13 11.9 0.1 1 8.9 0.1 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Ras PF00071.22 KXL45841.1 - 1.3e-52 177.7 0.0 1.6e-52 177.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXL45841.1 - 1.2e-21 77.1 0.0 1.8e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXL45841.1 - 2.1e-06 27.3 0.0 2.5e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXL45841.1 - 3.1e-06 26.9 0.1 9.8e-05 22.0 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KXL45841.1 - 3.4e-05 23.9 0.0 4.9e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXL45841.1 - 0.0036 17.2 0.2 3.5 7.5 0.2 2.2 1 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 KXL45841.1 - 0.007 15.7 0.0 0.0094 15.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 KXL45841.1 - 0.079 13.2 0.3 0.76 10.0 0.3 2.4 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KXL45841.1 - 0.087 12.0 0.2 0.59 9.3 0.2 1.9 1 1 0 2 2 2 0 NB-ARC domain DUF87 PF01935.17 KXL45841.1 - 0.091 12.8 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_24 PF13479.6 KXL45841.1 - 0.14 11.8 0.0 0.17 11.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 KXL45841.1 - 0.17 11.0 0.0 3.1 6.8 0.0 2.0 1 1 1 2 2 2 0 G-protein alpha subunit EMC1_C PF07774.13 KXL45842.1 - 1.7e-74 250.1 0.0 3e-74 249.3 0.0 1.4 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 KXL45842.1 - 5e-30 104.8 9.9 8.8e-27 94.2 3.4 3.4 4 0 0 4 4 4 2 PQQ-like domain PQQ PF01011.21 KXL45842.1 - 9.4e-13 47.4 0.9 0.024 14.5 0.0 7.2 7 0 0 7 7 7 2 PQQ enzyme repeat Spermine_synth PF01564.17 KXL45843.1 - 1e-06 28.3 0.0 1.7e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Haspin_kinase PF12330.8 KXL45844.1 - 4.5e-41 141.0 0.0 1.8e-40 139.0 0.0 1.8 1 1 0 1 1 1 1 Haspin like kinase domain RRM_1 PF00076.22 KXL45845.1 - 1.1e-19 70.0 0.0 1.6e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KXL45845.1 - 2.3e-07 31.3 10.2 2.3e-07 31.3 10.2 2.8 3 0 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 His_Phos_1 PF00300.22 KXL45847.1 - 2.8e-16 59.8 0.0 4.2e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pkinase PF00069.25 KXL45848.1 - 3.3e-49 167.6 0.0 7.7e-49 166.4 0.0 1.6 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL45848.1 - 1.2e-24 87.0 0.0 8.2e-22 77.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KXL45848.1 - 0.0034 16.7 0.0 0.0064 15.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXL45848.1 - 0.068 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KXL45848.1 - 0.13 11.8 0.3 1 8.9 0.0 2.2 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 DUF3665 PF12427.8 KXL45848.1 - 0.2 11.4 3.0 0.43 10.3 3.0 1.6 1 0 0 1 1 1 0 Branched-chain amino acid aminotransferase adh_short PF00106.25 KXL45851.1 - 3.2e-28 98.5 0.0 5e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL45851.1 - 1.2e-21 77.4 0.0 1.4e-20 73.9 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase F-box PF00646.33 KXL45853.1 - 4e-06 26.6 0.9 1.1e-05 25.1 0.9 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXL45853.1 - 0.012 15.5 0.1 0.012 15.5 0.1 2.8 4 0 0 4 4 4 0 F-box-like Carboxyl_trans PF01039.22 KXL45855.1 - 3.4e-139 464.7 0.0 4.1e-139 464.4 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 KXL45855.1 - 0.034 13.6 0.1 2.7 7.4 0.0 2.3 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) A_deamin PF02137.18 KXL45855.1 - 0.17 11.3 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Adenosine-deaminase (editase) domain Acyl-CoA_dh_1 PF00441.24 KXL45856.1 - 8.3e-41 139.7 0.5 1.4e-40 139.0 0.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXL45856.1 - 9e-34 116.5 0.1 2e-33 115.4 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KXL45856.1 - 1.9e-28 98.5 0.1 3.7e-28 97.6 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXL45856.1 - 1.1e-14 54.9 0.0 1.9e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KXL45856.1 - 0.00013 21.7 0.2 0.00047 19.9 0.2 1.8 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal COesterase PF00135.28 KXL45857.1 - 3.2e-81 273.7 0.0 4.3e-81 273.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXL45857.1 - 0.02 14.8 0.1 0.062 13.1 0.1 1.9 1 0 0 1 1 1 0 alpha/beta hydrolase fold PHD PF00628.29 KXL45858.1 - 6.3e-11 42.0 0.7 1.5e-10 40.8 0.7 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KXL45858.1 - 0.0046 16.5 4.1 0.0083 15.7 4.1 1.4 1 0 0 1 1 1 1 PHD-finger FAD_binding_6 PF00970.24 KXL45859.1 - 8.4e-32 109.5 0.0 1.3e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KXL45859.1 - 2e-29 102.5 0.0 2.8e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KXL45859.1 - 1.2e-05 25.5 0.0 0.0033 17.6 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain DUF1656 PF07869.12 KXL45859.1 - 0.23 11.5 2.3 0.45 10.5 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) AdoHcyase PF05221.17 KXL45862.1 - 1.6e-122 408.3 0.0 4.5e-72 242.7 0.0 3.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KXL45862.1 - 1.5e-84 282.0 3.2 2.2e-84 281.4 3.2 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KXL45862.1 - 1.3e-06 27.9 0.1 2.6e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KXL45862.1 - 0.0018 17.8 0.3 0.0036 16.9 0.3 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KXL45862.1 - 0.0033 17.7 0.1 0.0079 16.4 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.17 KXL45862.1 - 0.098 13.2 0.2 0.2 12.2 0.2 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Nefa_Nip30_N PF10187.9 KXL45863.1 - 1.1e-30 106.1 4.1 1.1e-30 106.1 4.1 1.4 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Aminopep PF10023.9 KXL45863.1 - 0.12 11.8 5.1 0.16 11.3 5.1 1.1 1 0 0 1 1 1 0 Putative aminopeptidase PSD5 PF07637.11 KXL45863.1 - 6.1 7.3 7.8 2 8.8 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1595) Aldo_ket_red PF00248.21 KXL45864.1 - 1.4e-48 165.6 0.0 6.5e-47 160.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family eIF-5a PF01287.20 KXL45865.1 - 1.2e-09 38.2 0.1 2.3e-09 37.2 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Acetyltransf_6 PF13480.7 KXL45865.1 - 0.053 13.7 0.0 2.8 8.1 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Glyco_hydro_17 PF00332.18 KXL45866.1 - 8.3e-14 51.9 5.6 7.1e-11 42.3 5.6 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Rick_17kDa_Anti PF05433.15 KXL45866.1 - 0.1 12.5 6.6 0.32 10.9 6.6 1.8 1 0 0 1 1 1 0 Glycine zipper 2TM domain RRS1 PF04939.12 KXL45866.1 - 0.5 10.2 2.1 0.91 9.4 0.1 2.2 3 0 0 3 3 3 0 Ribosome biogenesis regulatory protein (RRS1) Stealth_CR2 PF11380.8 KXL45868.1 - 0.21 11.7 0.5 0.59 10.3 0.4 1.7 1 1 0 1 1 1 0 Stealth protein CR2, conserved region 2 Peptidase_C97 PF05903.14 KXL45870.1 - 5.1e-32 110.8 0.0 6.2e-32 110.5 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 KXL45870.1 - 0.077 13.3 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin retinol acyltransferase SIR2 PF02146.17 KXL45871.1 - 1.1e-28 100.3 0.2 7.1e-28 97.7 0.0 2.3 2 1 0 2 2 2 1 Sir2 family Macoilin PF09726.9 KXL45871.1 - 2.7 6.4 9.5 4.3 5.8 9.5 1.2 1 0 0 1 1 1 0 Macoilin family Med16 PF11635.8 KXL45872.1 - 3e-69 233.8 0.0 4e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 Mediator complex subunit 16 CsbD PF05532.12 KXL45873.1 - 1.1e-06 28.4 0.6 0.0025 17.7 0.1 2.1 2 0 0 2 2 2 2 CsbD-like UPF0020 PF01170.18 KXL45874.1 - 3.3e-06 26.9 0.7 0.0016 18.1 0.7 2.4 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 KXL45874.1 - 0.0041 16.8 0.0 0.15 11.8 0.0 2.2 2 0 0 2 2 2 1 DNA methylase DUF987 PF06174.11 KXL45874.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF987) DUF4227 PF14004.6 KXL45874.1 - 0.17 11.9 0.0 0.38 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) WD40 PF00400.32 KXL45875.1 - 1.6e-20 73.0 19.6 0.00014 22.5 0.4 7.1 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL45875.1 - 1.6e-10 41.1 0.2 0.0014 18.9 0.0 4.3 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain ABC_tran PF00005.27 KXL45877.1 - 2.4e-46 157.7 0.3 6.6e-22 78.5 0.0 3.1 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 KXL45877.1 - 4.4e-21 74.7 5.7 4.4e-21 74.7 5.7 2.9 2 1 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 KXL45877.1 - 1e-14 55.1 3.6 0.0052 16.6 0.0 4.7 4 1 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXL45877.1 - 1.8e-09 37.4 0.5 0.078 12.4 0.0 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 KXL45877.1 - 9.5e-06 26.2 0.5 0.3 11.6 0.0 3.8 4 0 0 4 4 3 2 AAA domain AAA_22 PF13401.6 KXL45877.1 - 1.4e-05 25.4 0.1 0.2 11.9 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KXL45877.1 - 2.7e-05 23.8 0.2 0.15 11.8 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 KXL45877.1 - 3.2e-05 23.7 0.4 0.0048 16.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 KXL45877.1 - 6.7e-05 22.8 0.1 0.046 13.6 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KXL45877.1 - 8.2e-05 22.7 2.9 0.041 14.0 0.1 3.2 3 1 0 3 3 3 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KXL45877.1 - 0.00013 22.4 2.5 0.064 13.6 0.2 3.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_24 PF13479.6 KXL45877.1 - 0.00031 20.5 1.2 0.62 9.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.6 KXL45877.1 - 0.00035 21.1 19.6 0.015 15.8 0.0 4.9 4 1 1 6 6 6 2 AAA domain AAA_15 PF13175.6 KXL45877.1 - 0.00056 19.7 8.6 0.44 10.2 0.0 4.5 6 0 0 6 6 6 2 AAA ATPase domain AAA_33 PF13671.6 KXL45877.1 - 0.00061 20.0 0.4 1.7 8.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.6 KXL45877.1 - 0.00094 19.5 3.8 0.071 13.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 KXL45877.1 - 0.0018 18.2 0.1 0.84 9.5 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 KXL45877.1 - 0.0039 17.6 0.0 2.5 8.5 0.1 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KXL45877.1 - 0.0085 16.5 0.0 4.5 7.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 KXL45877.1 - 0.012 15.6 0.0 7.1 6.7 0.0 3.0 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 KXL45877.1 - 0.026 13.5 3.6 2.5 7.0 0.1 3.0 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 KXL45877.1 - 0.044 13.4 0.4 4.7 6.8 0.3 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 KXL45877.1 - 0.057 13.5 1.6 5.8 6.9 0.0 3.8 4 0 0 4 4 4 0 Dynamin family NTPase_1 PF03266.15 KXL45877.1 - 0.063 13.2 0.0 5.2 6.9 0.0 2.6 2 0 0 2 2 2 0 NTPase SRP54 PF00448.22 KXL45877.1 - 0.065 12.9 0.7 4.2 7.0 0.0 3.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain TsaE PF02367.17 KXL45877.1 - 0.069 13.1 0.0 17 5.4 0.0 2.8 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MobB PF03205.14 KXL45877.1 - 0.085 12.8 0.2 2.3 8.1 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.14 KXL45877.1 - 0.098 12.7 0.1 7.8 6.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Roc PF08477.13 KXL45877.1 - 0.14 12.4 0.1 7.3 6.8 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 KXL45877.1 - 0.17 11.8 0.6 6.2 6.7 0.0 2.9 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_27 PF13514.6 KXL45877.1 - 0.44 10.1 10.4 3.3 7.2 0.0 4.4 7 0 0 7 7 5 0 AAA domain AAA_17 PF13207.6 KXL45877.1 - 1.8 9.0 4.5 48 4.4 0.1 3.8 4 0 0 4 4 3 0 AAA domain DUF87 PF01935.17 KXL45877.1 - 2.6 8.1 11.6 4.2 7.4 0.0 4.3 5 0 0 5 5 4 0 Helicase HerA, central domain Cupin_2 PF07883.11 KXL45880.1 - 5e-11 42.2 0.6 7.3e-11 41.6 0.6 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KXL45880.1 - 4.3e-07 29.6 0.1 5.5e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 Cupin JmjC PF02373.22 KXL45880.1 - 0.011 16.2 0.1 0.051 14.0 0.1 1.9 1 1 0 1 1 1 0 JmjC domain, hydroxylase AraC_binding PF02311.19 KXL45880.1 - 0.016 15.1 0.6 0.025 14.5 0.6 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain DMSP_lyase PF16867.5 KXL45880.1 - 0.052 13.2 0.4 0.073 12.7 0.4 1.1 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase CENP-C_C PF11699.8 KXL45880.1 - 0.12 12.6 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Mif2/CENP-C like FdtA PF05523.11 KXL45880.1 - 0.14 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 WxcM-like, C-terminal TFIIA PF03153.13 KXL45882.1 - 2.7 7.9 15.1 1.1 9.2 11.7 1.9 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Totivirus_coat PF05518.11 KXL45882.1 - 5.6 4.9 14.2 14 3.6 14.2 1.7 1 0 0 1 1 1 0 Totivirus coat protein 2-Hacid_dh_C PF02826.19 KXL45883.1 - 4e-55 185.9 0.0 5.4e-55 185.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXL45883.1 - 4e-18 65.4 0.0 4.7e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXL45883.1 - 0.00046 20.4 0.2 0.00087 19.5 0.2 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KXL45883.1 - 0.0006 19.4 0.1 0.00095 18.8 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Fungal_trans PF04082.18 KXL45884.1 - 8.7e-09 34.8 0.0 2.9e-08 33.1 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL45884.1 - 3.1e-05 24.0 5.7 5.7e-05 23.1 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro-kuma_activ PF09286.11 KXL45886.1 - 3.6e-27 95.4 0.0 5.4e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Sugar_tr PF00083.24 KXL45887.1 - 3.5e-39 134.9 16.6 8.8e-39 133.6 16.6 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL45887.1 - 2.4e-31 109.0 42.8 5.4e-27 94.6 24.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.8 KXL45887.1 - 2.5e-06 26.4 7.3 5.1e-06 25.4 3.0 2.2 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like PHO4 PF01384.20 KXL45887.1 - 0.0074 15.4 0.1 0.027 13.5 0.0 1.9 1 1 0 1 1 1 1 Phosphate transporter family 2OG-FeII_Oxy PF03171.20 KXL45888.1 - 2.9e-14 53.4 0.0 5.4e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KXL45888.1 - 4.8e-11 43.4 0.0 8e-07 29.8 0.0 2.2 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal SARAF PF06682.12 KXL45889.1 - 0.62 9.7 6.4 0.18 11.4 0.9 2.7 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Protamine_P1 PF00260.20 KXL45890.1 - 0.83 9.8 6.6 0.23 11.6 1.8 2.2 2 0 0 2 2 2 0 Protamine P1 Med8 PF10232.9 KXL45891.1 - 1e-13 51.4 0.0 1.4e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Vfa1 PF08432.10 KXL45892.1 - 0.087 13.2 5.7 0.19 12.1 5.7 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop14 PF04147.12 KXL45892.1 - 0.18 10.0 19.7 0.13 10.5 16.9 1.8 2 0 0 2 2 2 0 Nop14-like family BUD22 PF09073.10 KXL45892.1 - 1.3 8.2 17.0 2.4 7.4 17.0 1.4 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 KXL45892.1 - 1.4 8.6 21.6 3 7.5 21.6 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FYDLN_acid PF09538.10 KXL45892.1 - 1.9 9.2 18.5 5 7.9 18.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CDC45 PF02724.14 KXL45892.1 - 2.6 6.3 13.3 4.2 5.6 13.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop25 PF09805.9 KXL45892.1 - 3.3 8.2 14.0 9.9 6.6 14.0 1.8 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) PPP4R2 PF09184.11 KXL45892.1 - 3.4 7.2 20.6 6.4 6.3 20.6 1.4 1 0 0 1 1 1 0 PPP4R2 Spt5_N PF11942.8 KXL45895.1 - 1.3e-18 67.8 10.4 1.3e-18 67.8 10.4 4.0 3 1 1 4 4 4 1 Spt5 transcription elongation factor, acidic N-terminal Spt5-NGN PF03439.13 KXL45895.1 - 1.3e-18 66.6 0.0 2.6e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section CTD PF12815.7 KXL45895.1 - 8.4e-15 55.1 38.9 1.1e-09 38.8 19.0 3.9 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.29 KXL45895.1 - 4.2e-07 29.7 25.5 0.033 14.2 1.9 5.1 5 0 0 5 5 5 4 KOW motif DUF3912 PF13051.6 KXL45895.1 - 0.00072 19.8 1.8 2 8.7 0.1 3.4 4 0 0 4 4 4 2 Protein of unknown function (DUF3912) DUF4230 PF14014.6 KXL45895.1 - 0.073 13.3 0.0 9.1 6.5 0.0 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF4230) mRNA_triPase PF02940.15 KXL45896.1 - 8.7e-09 35.4 0.0 9.4e-09 35.3 0.0 1.0 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain mRNA_triPase PF02940.15 KXL45897.1 - 5.5e-07 29.5 0.0 1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain SUIM_assoc PF16619.5 KXL45897.1 - 4.9e-05 23.3 10.4 60 3.8 0.0 5.0 3 2 1 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 Zip PF02535.22 KXL45897.1 - 9.4 5.3 8.0 16 4.6 8.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter RPN2_C PF18004.1 KXL45898.1 - 1.7e-45 154.8 1.1 2.8e-45 154.1 1.1 1.4 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KXL45898.1 - 4.9e-39 130.8 12.7 7.2e-09 35.7 0.0 8.1 7 0 0 7 7 7 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KXL45898.1 - 7.6e-19 67.9 2.0 1.1e-13 51.4 0.0 4.9 4 1 2 6 6 6 2 HEAT repeats HEAT_EZ PF13513.6 KXL45898.1 - 0.00028 21.3 0.2 0.021 15.3 0.0 4.2 3 1 1 4 4 4 1 HEAT-like repeat HEAT PF02985.22 KXL45898.1 - 0.006 16.7 0.2 44 4.7 0.1 4.4 4 0 0 4 4 4 0 HEAT repeat ANAPC3 PF12895.7 KXL45898.1 - 0.0061 16.8 0.7 0.85 9.9 0.2 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KXL45898.1 - 0.12 12.9 5.3 0.7 10.4 0.7 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat HEAT_PBS PF03130.16 KXL45898.1 - 0.95 10.3 2.9 4.2 8.3 0.0 3.7 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Polysacc_synt_4 PF04669.13 KXL45899.1 - 3.3e-18 65.9 0.0 1.3e-08 34.6 0.0 2.1 1 1 1 2 2 2 2 Polysaccharide biosynthesis Glyco_hydro_35 PF01301.19 KXL45900.1 - 2.8e-79 267.0 2.7 4.5e-79 266.3 2.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KXL45900.1 - 3.4e-53 179.1 8.1 7e-30 103.9 0.0 3.1 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KXL45900.1 - 1.9e-47 161.4 5.8 3.9e-47 160.4 5.8 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KXL45900.1 - 3.9e-21 74.4 0.1 4.5e-20 71.0 0.0 2.7 3 0 0 3 3 3 1 Beta-galactosidase, domain 3 Filament PF00038.21 KXL45901.1 - 0.0075 15.9 8.3 0.0075 15.9 8.3 2.3 2 0 0 2 2 2 1 Intermediate filament protein RPW8 PF05659.11 KXL45901.1 - 0.0085 15.8 0.6 0.055 13.2 0.3 2.4 2 0 0 2 2 2 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF1635 PF07795.11 KXL45901.1 - 0.1 12.4 0.2 0.1 12.4 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1635) DUF948 PF06103.11 KXL45901.1 - 0.41 10.9 1.6 1.3 9.3 0.6 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SKA1 PF07160.12 KXL45901.1 - 0.43 10.4 8.5 0.43 10.4 7.0 1.8 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 PspB PF06667.12 KXL45901.1 - 0.45 10.6 4.0 1.3 9.2 2.7 2.5 2 0 0 2 2 1 0 Phage shock protein B DUF294_C PF10335.9 KXL45901.1 - 0.48 10.2 5.9 0.21 11.4 3.0 1.9 2 0 0 2 2 2 0 Putative nucleotidyltransferase substrate binding domain TBCA PF02970.16 KXL45901.1 - 0.63 10.4 9.5 1.4 9.3 4.7 3.0 2 0 0 2 2 2 0 Tubulin binding cofactor A DUF1043 PF06295.12 KXL45901.1 - 0.66 10.0 5.5 1.8 8.5 5.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) FAA_hydro_N_2 PF18288.1 KXL45901.1 - 0.84 10.1 4.7 3.1 8.3 0.2 3.6 3 1 0 4 4 3 0 Fumarylacetoacetase N-terminal domain 2 DUF4250 PF14056.6 KXL45901.1 - 0.99 9.4 2.7 21 5.1 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) V_ATPase_I PF01496.19 KXL45901.1 - 1.1 7.1 4.8 1.3 6.8 4.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fibin PF15819.5 KXL45901.1 - 1.3 8.7 8.4 10 5.8 2.8 2.9 1 1 1 3 3 3 0 Fin bud initiation factor homologue Nup88 PF10168.9 KXL45901.1 - 1.7 6.3 10.6 2.6 5.7 10.6 1.2 1 0 0 1 1 1 0 Nuclear pore component TolA_bind_tri PF16331.5 KXL45901.1 - 2.3 8.4 11.8 0.22 11.7 3.4 3.4 4 0 0 4 4 4 0 TolA binding protein trimerisation FlaC_arch PF05377.11 KXL45901.1 - 2.9 8.4 5.7 8.3 6.9 1.5 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.9 KXL45901.1 - 3.2 8.1 13.2 57 4.1 0.1 4.8 3 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prominin PF05478.11 KXL45901.1 - 5.7 4.8 5.2 8.5 4.2 4.5 1.5 1 1 0 1 1 1 0 Prominin LMBR1 PF04791.16 KXL45901.1 - 6 5.6 6.5 8.7 5.1 6.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Sec34 PF04136.15 KXL45901.1 - 6.2 6.7 8.3 19 5.1 2.9 3.4 3 1 0 3 3 3 0 Sec34-like family CTP_transf_like PF01467.26 KXL45902.1 - 8.1e-05 22.8 0.0 0.0002 21.5 0.0 1.7 1 1 0 1 1 1 1 Cytidylyltransferase-like Phosphoesterase PF04185.14 KXL45904.1 - 2.4e-37 129.0 3.3 2.3e-36 125.7 1.5 2.5 1 1 1 2 2 2 2 Phosphoesterase family Cu-oxidase_3 PF07732.15 KXL45905.1 - 3.2e-43 146.5 2.6 3.2e-43 146.5 2.6 2.3 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXL45905.1 - 3.2e-34 117.6 5.0 1.7e-30 105.5 0.0 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KXL45905.1 - 2.4e-32 112.2 0.0 9.1e-31 107.1 0.0 2.4 2 1 0 2 2 2 1 Multicopper oxidase tRNA-synt_2d PF01409.20 KXL45906.1 - 3.7e-86 288.6 0.0 4.8e-86 288.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 KXL45906.1 - 5.6e-14 52.2 0.6 1.2e-13 51.2 0.1 1.8 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 KXL45906.1 - 1.1e-06 28.3 0.0 0.014 14.8 0.0 2.4 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 KXL45906.1 - 0.00012 21.3 0.5 0.0046 16.1 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) DUF5337 PF17272.2 KXL45907.1 - 0.0086 15.9 2.0 0.0086 15.9 2.0 2.7 2 1 1 3 3 3 1 Family of unknown function (DUF5337) MARVEL PF01284.23 KXL45907.1 - 0.041 13.9 19.5 0.06 13.4 19.5 1.2 1 0 0 1 1 1 0 Membrane-associating domain H_PPase PF03030.16 KXL45907.1 - 0.062 11.9 3.8 0.075 11.6 3.8 1.1 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase DUF1980 PF09323.10 KXL45907.1 - 0.1 12.5 0.7 0.51 10.2 0.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1980) FA_hydroxylase PF04116.13 KXL45907.1 - 0.18 12.2 0.0 0.18 12.2 0.0 2.3 1 1 1 2 2 2 0 Fatty acid hydroxylase superfamily DUF2304 PF10066.9 KXL45907.1 - 0.98 9.7 9.3 1.4 9.1 2.6 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) DUF2917 PF11142.8 KXL45908.1 - 0.029 13.8 0.0 0.066 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2917) Mannosyl_trans PF05007.13 KXL45910.1 - 3.4e-68 230.3 18.2 4.9e-66 223.2 18.2 2.2 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 KXL45910.1 - 1.5e-15 57.1 0.7 1.5e-15 57.1 0.7 1.7 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U GT87 PF09594.10 KXL45910.1 - 2e-06 27.7 14.1 2e-06 27.7 14.1 3.1 2 1 0 2 2 2 1 Glycosyltransferase family 87 VIT1 PF01988.19 KXL45911.1 - 9.6e-58 195.6 9.5 1.1e-57 195.4 9.5 1.0 1 0 0 1 1 1 1 VIT family p450 PF00067.22 KXL45912.1 - 7e-33 114.1 0.0 1.2e-32 113.3 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Erf4 PF10256.9 KXL45913.1 - 5.6e-32 110.3 0.0 6.5e-32 110.1 0.0 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family WD40 PF00400.32 KXL45914.1 - 8.3e-65 213.2 15.1 2e-09 37.9 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL45914.1 - 2.6e-22 78.9 0.1 0.00015 22.0 0.0 6.6 1 1 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Tup_N PF08581.10 KXL45914.1 - 1e-16 61.0 11.2 2.3e-16 59.8 11.2 1.6 1 0 0 1 1 1 1 Tup N-terminal WD40_like PF17005.5 KXL45914.1 - 5e-09 35.9 0.0 0.15 11.4 0.0 5.5 4 1 1 5 5 5 2 WD40-like domain Ge1_WD40 PF16529.5 KXL45914.1 - 1.7e-07 30.5 0.5 0.54 9.2 0.0 5.5 1 1 5 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KXL45914.1 - 7.2e-06 24.8 0.1 0.00029 19.5 0.0 2.4 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.8 KXL45914.1 - 1.5e-05 23.9 0.2 1.3 7.6 0.0 4.3 1 1 4 5 5 5 2 Nucleoporin Nup120/160 eIF2A PF08662.11 KXL45914.1 - 3.2e-05 23.9 0.0 0.061 13.2 0.0 3.4 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A MMS1_N PF10433.9 KXL45914.1 - 0.0012 17.6 0.0 0.3 9.7 0.0 2.2 2 0 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term Nbas_N PF15492.6 KXL45914.1 - 0.018 14.4 0.1 11 5.2 0.0 3.0 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Coatomer_WDAD PF04053.14 KXL45914.1 - 0.062 12.3 0.0 0.38 9.7 0.0 1.9 1 1 1 2 2 2 0 Coatomer WD associated region DUF3037 PF11236.8 KXL45914.1 - 0.084 13.3 1.0 0.17 12.3 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) PD40 PF07676.12 KXL45914.1 - 0.11 12.4 0.1 19 5.3 0.0 4.1 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat VID27 PF08553.10 KXL45914.1 - 0.22 10.5 0.0 4.5 6.2 0.0 2.4 1 1 2 3 3 3 0 VID27 C-terminal WD40-like domain Glyco_transf_22 PF03901.17 KXL45916.1 - 1.4e-60 205.7 20.9 1.9e-60 205.3 20.9 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Wzy_C PF04932.15 KXL45916.1 - 0.39 10.3 3.9 0.46 10.1 1.0 2.4 2 0 0 2 2 2 0 O-Antigen ligase DUF1964 PF09244.10 KXL45917.1 - 0.071 13.5 0.1 0.12 12.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1964) Sugar_tr PF00083.24 KXL45918.1 - 3e-77 260.4 27.7 3.5e-77 260.2 27.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL45918.1 - 1.6e-06 27.3 36.8 1.6e-06 27.3 36.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXL45918.1 - 2.8 6.7 16.4 1.1 8.1 9.4 2.3 2 0 0 2 2 2 0 MFS_1 like family DUF3272 PF11676.8 KXL45918.1 - 8.2 6.8 8.5 4.5 7.6 2.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3272) Glyco_hydro_67M PF07488.12 KXL45919.1 - 2.7e-140 467.1 0.0 3.9e-140 466.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 KXL45919.1 - 7.6e-89 297.1 1.2 3.3e-88 295.0 0.6 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.14 KXL45919.1 - 1e-22 80.7 0.0 1.9e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.15 KXL45919.1 - 0.016 16.0 0.0 0.04 14.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 ABC_tran PF00005.27 KXL45920.1 - 2.4e-47 160.9 0.1 4.5e-22 79.0 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KXL45920.1 - 6.8e-23 80.5 5.0 6.8e-23 80.5 5.0 3.1 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.6 KXL45920.1 - 1.2e-19 71.3 1.0 0.00048 20.0 0.1 4.4 4 1 1 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXL45920.1 - 7.5e-11 41.9 0.4 0.27 10.6 0.0 4.5 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXL45920.1 - 2.9e-09 36.5 0.1 0.0036 17.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KXL45920.1 - 2.4e-08 34.7 6.6 0.01 16.4 0.1 3.7 4 0 0 4 4 4 2 AAA domain RsgA_GTPase PF03193.16 KXL45920.1 - 2.3e-07 30.9 0.3 0.00095 19.1 0.1 2.7 3 0 0 3 3 2 2 RsgA GTPase AAA_15 PF13175.6 KXL45920.1 - 5.2e-07 29.7 2.3 0.023 14.4 0.0 3.4 3 1 1 4 4 3 2 AAA ATPase domain AAA_16 PF13191.6 KXL45920.1 - 1.5e-06 28.7 0.0 0.029 14.7 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 KXL45920.1 - 4e-06 27.4 0.0 0.077 13.5 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 KXL45920.1 - 1.6e-05 25.2 0.0 0.065 13.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KXL45920.1 - 3e-05 24.1 0.0 0.086 12.9 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 KXL45920.1 - 5.6e-05 23.4 0.0 0.027 14.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KXL45920.1 - 5.8e-05 23.5 0.0 0.59 10.6 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KXL45920.1 - 6.1e-05 23.0 0.1 0.14 12.1 0.0 2.6 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.22 KXL45920.1 - 0.00024 21.5 0.0 1.1 9.7 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_27 PF13514.6 KXL45920.1 - 0.00064 19.4 1.0 0.36 10.4 0.0 2.8 3 0 0 3 3 2 2 AAA domain Roc PF08477.13 KXL45920.1 - 0.00086 19.5 0.0 2.1 8.6 0.0 2.9 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 KXL45920.1 - 0.0012 18.1 0.0 4.3 6.5 0.0 3.2 3 0 0 3 3 3 1 NB-ARC domain AAA_5 PF07728.14 KXL45920.1 - 0.0018 18.2 0.0 2.8 7.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KXL45920.1 - 0.0037 17.3 0.0 3.9 7.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KXL45920.1 - 0.0038 17.0 0.5 2.7 7.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain Phage_tail_2 PF06199.11 KXL45920.1 - 0.0055 16.8 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 Phage tail tube protein AAA_33 PF13671.6 KXL45920.1 - 0.0092 16.1 2.2 2.1 8.5 0.0 3.4 4 0 0 4 4 4 1 AAA domain ATPase_2 PF01637.18 KXL45920.1 - 0.013 15.5 0.2 2.1 8.2 0.0 2.7 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KXL45920.1 - 0.017 14.6 0.0 1.6 8.2 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Ras PF00071.22 KXL45920.1 - 0.018 14.6 0.1 7.6 6.1 0.0 2.6 3 0 0 3 3 2 0 Ras family AAA_25 PF13481.6 KXL45920.1 - 0.025 14.2 0.1 1.9 8.0 0.0 3.2 3 1 1 4 4 4 0 AAA domain Dynamin_N PF00350.23 KXL45920.1 - 0.032 14.3 3.0 5.6 7.0 0.0 3.7 2 1 1 3 3 3 0 Dynamin family DUF2813 PF11398.8 KXL45920.1 - 0.045 13.0 0.1 6.3 6.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) TsaE PF02367.17 KXL45920.1 - 0.051 13.6 0.2 19 5.3 0.0 3.3 2 1 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 KXL45920.1 - 0.058 13.3 0.1 15 5.4 0.0 2.7 3 0 0 3 3 2 0 Rad17 P-loop domain MCM PF00493.23 KXL45920.1 - 0.06 12.4 0.0 3.6 6.6 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain ABC_ATPase PF09818.9 KXL45920.1 - 0.098 11.4 0.2 15 4.3 0.0 3.2 3 1 0 3 3 3 0 Predicted ATPase of the ABC class DUF815 PF05673.13 KXL45920.1 - 0.1 11.7 0.1 3.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DAP3 PF10236.9 KXL45920.1 - 0.54 9.4 2.7 8.4 5.5 0.0 2.8 3 0 0 3 3 2 0 Mitochondrial ribosomal death-associated protein 3 DUF87 PF01935.17 KXL45920.1 - 4.6 7.3 5.1 25 4.8 0.0 3.5 4 1 0 4 4 3 0 Helicase HerA, central domain Skp1 PF01466.19 KXL45921.1 - 6e-29 99.9 2.5 8.2e-29 99.5 0.7 2.1 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KXL45921.1 - 1.2e-21 76.7 0.2 2.8e-21 75.5 0.1 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain MRP-S33 PF08293.11 KXL45922.1 - 7.3e-31 106.3 0.1 9.4e-31 105.9 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Ribonuclease_3 PF00636.26 KXL45923.1 - 1.6e-16 60.8 0.0 2.7e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KXL45923.1 - 6.5e-14 52.2 0.0 9.4e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like SMI1_KNR4 PF09346.10 KXL45924.1 - 1.4e-32 112.9 0.0 3.4e-32 111.6 0.0 1.7 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) CopD PF05425.13 KXL45925.1 - 0.28 11.6 8.1 0.073 13.5 3.2 2.5 3 0 0 3 3 3 0 Copper resistance protein D SIT PF15330.6 KXL45925.1 - 0.37 11.3 0.8 1 9.8 0.8 1.7 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT TMEM220 PF15071.6 KXL45925.1 - 1.2 9.9 4.1 1.3 9.8 0.1 2.7 2 1 1 3 3 3 0 Transmembrane family 220, helix Zn_clus PF00172.18 KXL45926.1 - 1.1e-07 31.9 9.8 1.1e-07 31.9 9.8 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.24 KXL45928.1 - 6.2e-29 101.1 0.4 1e-28 100.4 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXL45928.1 - 3e-19 69.0 0.0 5.4e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KXL45928.1 - 2.2e-15 57.3 0.1 1.2e-14 55.0 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXL45928.1 - 2.1e-12 47.4 1.3 3.4e-12 46.8 1.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CBM_35 PF16990.5 KXL45929.1 - 0.2 11.9 0.0 0.27 11.5 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate binding module (family 35) Iso_dh PF00180.20 KXL45930.1 - 2.3e-88 296.7 0.0 2.6e-88 296.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ECD PF18432.1 KXL45930.1 - 0.14 12.2 0.1 0.24 11.4 0.1 1.3 1 0 0 1 1 1 0 Extracellular Cadherin domain Exo_endo_phos PF03372.23 KXL45931.1 - 5.6e-06 26.0 0.1 6.4e-06 25.9 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2374 PF09574.10 KXL45931.1 - 0.084 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (Duf2374) Ccdc124 PF06244.12 KXL45932.1 - 2.5e-25 89.5 23.9 2.5e-25 89.5 23.9 2.3 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 GST_C_3 PF14497.6 KXL45933.1 - 3.3e-28 97.8 0.5 6.1e-28 96.9 0.5 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXL45933.1 - 7.7e-07 29.2 0.1 1.3e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXL45933.1 - 0.0041 17.1 0.0 0.0074 16.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Zn_clus PF00172.18 KXL45935.1 - 2.9e-05 24.1 8.0 6.3e-05 23.0 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXL45935.1 - 0.011 14.7 0.5 0.024 13.7 0.5 1.6 1 0 0 1 1 1 0 Fungal specific transcription factor domain Lactamase_B PF00753.27 KXL45936.1 - 4.6e-06 26.8 3.1 1e-05 25.7 1.4 2.6 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily PdxA PF04166.12 KXL45937.1 - 1.5e-16 60.7 0.2 3.9e-14 52.7 0.2 2.2 1 1 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA Iso_dh PF00180.20 KXL45937.1 - 0.015 14.4 0.1 0.018 14.2 0.1 1.2 1 0 0 1 1 1 0 Isocitrate/isopropylmalate dehydrogenase Asparaginase PF00710.20 KXL45938.1 - 7.4e-59 198.5 0.0 1.2e-58 197.8 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KXL45938.1 - 3.1e-25 88.6 0.0 5.8e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 KXL45938.1 - 2.8e-19 69.5 0.0 8.6e-12 45.5 0.0 2.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXL45938.1 - 7.5e-10 38.8 1.8 2.3e-05 24.6 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KXL45938.1 - 5.3e-09 36.5 0.1 3.8e-06 27.3 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXL45938.1 - 1.1e-07 31.6 0.4 0.0075 16.7 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KXL45938.1 - 1.2e-06 28.7 0.0 3.1e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) GrpE PF01025.19 KXL45940.1 - 3.7e-36 124.3 0.1 4.8e-36 123.9 0.1 1.2 1 0 0 1 1 1 1 GrpE Mg_chelatase_C PF13335.6 KXL45940.1 - 0.079 13.6 1.0 0.2 12.3 0.3 2.0 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal GrpE PF01025.19 KXL45942.1 - 4.9e-12 45.8 2.0 6.4e-12 45.4 2.0 1.1 1 0 0 1 1 1 1 GrpE LEA_3 PF03242.13 KXL45942.1 - 0.073 13.8 0.3 0.15 12.8 0.0 1.7 2 0 0 2 2 2 0 Late embryogenesis abundant protein DLP_helical PF18709.1 KXL45942.1 - 0.13 11.4 1.5 0.17 11.1 1.5 1.1 1 0 0 1 1 1 0 Dynamin-like helical domain MMR_HSR1 PF01926.23 KXL45948.1 - 5.8e-19 68.3 0.0 9.8e-19 67.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXL45948.1 - 7.2e-07 28.9 0.0 4.3e-06 26.4 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KXL45948.1 - 6.7e-06 26.1 0.2 0.00011 22.2 0.1 2.5 3 0 0 3 3 3 1 RsgA GTPase Dynamin_N PF00350.23 KXL45948.1 - 4e-05 23.7 0.0 0.026 14.6 0.0 2.3 2 0 0 2 2 2 2 Dynamin family FeoB_N PF02421.18 KXL45948.1 - 0.0031 17.1 0.0 0.026 14.1 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B ABC_tran PF00005.27 KXL45948.1 - 0.033 14.7 0.0 0.049 14.1 0.0 1.5 1 1 0 1 1 1 0 ABC transporter Roc PF08477.13 KXL45948.1 - 0.13 12.5 0.1 0.65 10.2 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Complex1_LYR_2 PF13233.6 KXL45949.1 - 4.9e-22 78.5 2.2 6.6e-22 78.1 2.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like DUF2791 PF10923.8 KXL45949.1 - 0.031 13.1 0.1 0.035 13.0 0.1 1.0 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Complex1_LYR PF05347.15 KXL45949.1 - 0.063 13.3 2.6 0.071 13.2 0.8 2.1 1 1 0 2 2 2 0 Complex 1 protein (LYR family) LRR_6 PF13516.6 KXL45950.1 - 0.00011 22.0 10.3 0.41 10.8 0.4 4.6 5 0 0 5 5 5 3 Leucine Rich repeat LRR_8 PF13855.6 KXL45950.1 - 0.0011 18.7 1.8 7.9 6.3 0.1 3.5 3 0 0 3 3 3 3 Leucine rich repeat LRR_1 PF00560.33 KXL45950.1 - 0.0012 19.1 0.1 16 6.5 0.0 4.2 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_4 PF12799.7 KXL45950.1 - 0.0056 17.1 7.6 0.042 14.3 0.9 3.7 3 1 0 4 4 4 1 Leucine Rich repeats (2 copies) peroxidase PF00141.23 KXL45951.1 - 1.6e-45 155.6 0.0 2.6e-45 154.9 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Acetyltransf_7 PF13508.7 KXL45952.1 - 4.1e-10 39.9 0.0 4.8e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXL45952.1 - 3.6e-09 36.6 0.0 5e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXL45952.1 - 8.7e-08 32.4 0.0 1.1e-07 32.0 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KXL45952.1 - 0.017 15.2 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXL45952.1 - 0.11 12.6 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acid_PPase PF12689.7 KXL45953.1 - 5.7e-28 97.9 0.0 6.6e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase WD40 PF00400.32 KXL45955.1 - 9.8e-17 61.0 4.5 7.8e-07 29.7 0.1 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.8 KXL45955.1 - 0.00046 19.0 2.2 1.2 7.7 0.1 3.0 1 1 1 3 3 3 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KXL45955.1 - 0.0072 16.6 0.1 0.5 10.7 0.0 3.0 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain YoeB_toxin PF06769.14 KXL45955.1 - 0.11 12.5 0.1 0.29 11.2 0.1 1.7 2 0 0 2 2 2 0 YoeB-like toxin of bacterial type II toxin-antitoxin system Acid_PPase PF12689.7 KXL45956.1 - 3.1e-37 128.0 0.0 3.5e-37 127.9 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase WD40 PF00400.32 KXL45957.1 - 3e-29 100.6 14.9 1.4e-05 25.8 0.5 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat F-box-like PF12937.7 KXL45957.1 - 1.3e-09 37.8 0.0 2.4e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXL45957.1 - 3.5e-06 26.7 0.0 8.4e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KXL45957.1 - 0.0022 18.2 0.2 3.3 8.1 0.0 3.6 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXL45957.1 - 0.0077 14.9 0.9 2 6.9 0.1 3.0 2 1 0 3 3 3 2 Nucleoporin Nup120/160 F-box_4 PF15966.5 KXL45957.1 - 0.009 15.9 0.0 0.035 14.0 0.0 2.0 1 0 0 1 1 1 1 F-box DUF1295 PF06966.12 KXL45958.1 - 2e-42 145.3 0.1 8.6e-41 140.0 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KXL45958.1 - 0.029 14.8 0.0 0.22 12.0 0.0 2.4 3 0 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 KXL45958.1 - 0.065 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase WD40 PF00400.32 KXL45959.1 - 9.8e-25 86.4 13.0 0.00017 22.3 0.0 8.1 8 0 0 8 8 8 5 WD domain, G-beta repeat F-box-like PF12937.7 KXL45959.1 - 8.5e-11 41.6 0.3 2e-10 40.4 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXL45959.1 - 1.3e-10 40.9 0.4 2.9e-10 39.8 0.4 1.5 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KXL45959.1 - 0.00021 21.5 0.6 0.62 10.4 0.0 3.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KXL45959.1 - 0.0048 16.3 0.1 0.83 8.9 0.1 2.4 2 0 0 2 2 2 2 WD40-like domain Nup160 PF11715.8 KXL45959.1 - 0.0067 15.1 0.6 4.8 5.7 0.0 3.1 4 0 0 4 4 4 2 Nucleoporin Nup120/160 PH_10 PF15411.6 KXL45960.1 - 6.8e-39 132.9 0.0 1.3e-38 132.0 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.11 KXL45960.1 - 1.3e-31 108.7 0.0 4e-31 107.1 0.0 1.8 2 0 0 2 2 2 1 CDC24 Calponin RhoGEF PF00621.20 KXL45960.1 - 2e-27 96.6 0.1 3.4e-27 95.9 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 KXL45960.1 - 2.3e-09 37.0 0.0 4.8e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 PB1 domain PH PF00169.29 KXL45960.1 - 0.0025 18.3 0.1 0.0052 17.3 0.1 1.5 1 0 0 1 1 1 1 PH domain DASH_Dad1 PF08649.10 KXL45960.1 - 0.18 12.0 0.0 0.48 10.7 0.0 1.8 1 0 0 1 1 1 0 DASH complex subunit Dad1 Periviscerokin PF08259.11 KXL45960.1 - 0.45 10.9 3.5 0.39 11.1 0.4 2.7 2 0 0 2 2 2 0 Periviscerokinin family DHBP_synthase PF00926.19 KXL45961.1 - 2.4e-80 268.6 0.1 2.7e-80 268.4 0.1 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase zf-C2H2 PF00096.26 KXL45963.1 - 1.5e-19 69.2 26.5 3.7e-05 23.9 1.7 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXL45963.1 - 4.2e-16 58.6 29.9 1.7e-06 28.1 1.2 5.5 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXL45963.1 - 2.7e-10 40.2 24.1 0.0042 17.8 1.3 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXL45963.1 - 1.3e-06 28.5 0.3 0.61 10.4 0.0 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXL45963.1 - 0.0051 17.2 8.5 7.5 7.1 0.4 4.2 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 KXL45963.1 - 0.013 15.7 1.2 2.6 8.2 0.0 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_11 PF16622.5 KXL45963.1 - 0.02 14.6 0.8 0.02 14.6 0.8 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type zf_UBZ PF18439.1 KXL45963.1 - 0.069 12.8 0.9 1.2 8.8 0.2 3.0 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-MYST PF17772.1 KXL45963.1 - 0.13 11.8 1.4 4.8 6.9 0.0 3.0 3 0 0 3 3 3 0 MYST family zinc finger domain zf-CRD PF17979.1 KXL45963.1 - 2.7 8.1 7.5 6.5 6.8 1.5 2.3 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions FOXP-CC PF16159.5 KXL45963.1 - 4 8.2 7.2 27 5.5 0.5 3.7 3 1 1 4 4 4 0 FOXP coiled-coil domain Zn-ribbon_8 PF09723.10 KXL45963.1 - 8.2 6.6 8.4 1e+02 3.1 1.1 3.1 1 1 2 3 3 3 0 Zinc ribbon domain Fungal_trans_2 PF11951.8 KXL45965.1 - 6.7e-23 81.1 3.1 1e-18 67.4 2.4 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL45965.1 - 1.2e-07 31.7 10.2 1.2e-07 31.7 10.2 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_Tnp_IS1 PF03811.13 KXL45965.1 - 0.43 10.4 3.3 1.1 9.0 0.2 2.4 2 0 0 2 2 2 0 InsA N-terminal domain Glyco_hydro_127 PF07944.12 KXL45966.1 - 3.9e-21 75.1 1.0 6.6e-20 71.1 0.1 2.2 2 1 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 Cadherin-like PF12733.7 KXL45966.1 - 0.11 13.1 0.1 0.48 11.0 0.0 2.1 2 0 0 2 2 2 0 Cadherin-like beta sandwich domain HEAT_2 PF13646.6 KXL45967.1 - 9.5e-05 22.7 1.6 0.53 10.7 0.3 5.7 2 1 3 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 KXL45967.1 - 0.00042 20.7 2.9 0.0017 18.8 0.0 3.6 4 0 0 4 4 4 1 HEAT-like repeat HEAT PF02985.22 KXL45967.1 - 0.00088 19.3 3.1 0.26 11.6 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 KXL45967.1 - 0.0033 17.5 0.6 0.16 12.0 0.0 4.2 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 PUL PF08324.11 KXL45967.1 - 0.016 14.4 0.7 0.32 10.2 0.1 2.7 2 0 0 2 2 2 0 PUL domain Translin PF01997.16 KXL45967.1 - 0.023 14.7 0.5 0.31 11.0 0.0 2.9 2 1 1 3 3 3 0 Translin family Ribonuc_2-5A PF06479.12 KXL45967.1 - 0.035 14.3 2.6 0.25 11.5 0.1 3.1 3 0 0 3 3 3 0 Ribonuclease 2-5A Ubiq_cyt_C_chap PF03981.12 KXL45968.1 - 9e-34 116.6 1.9 1.2e-33 116.2 1.9 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone mRNA_cap_enzyme PF01331.19 KXL45969.1 - 2.7e-44 151.3 0.0 1e-43 149.5 0.0 1.9 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KXL45969.1 - 3.2e-30 105.0 0.1 3.2e-30 105.0 0.1 1.6 2 0 0 2 2 2 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 KXL45969.1 - 0.013 15.2 4.0 0.12 12.0 0.0 3.0 2 1 1 3 3 3 0 ATP dependent DNA ligase domain U1snRNP70_N PF12220.8 KXL45969.1 - 0.39 11.4 9.9 0.8 10.4 9.9 1.4 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF2722 PF10846.8 KXL45969.1 - 0.82 8.5 10.4 1.2 8.0 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Med3 PF11593.8 KXL45969.1 - 1.2 8.2 9.4 1.7 7.8 9.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Spt20 PF12090.8 KXL45969.1 - 1.6 8.3 9.5 2.6 7.6 9.5 1.3 1 0 0 1 1 1 0 Spt20 family FKBP_N PF01346.18 KXL45969.1 - 1.7 9.7 8.2 2.9 8.9 8.2 1.3 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase ketoacyl-synt PF00109.26 KXL45972.1 - 4.1e-59 200.2 2.1 6e-58 196.4 0.2 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KXL45972.1 - 1.4e-36 125.1 0.9 2.7e-36 124.1 0.9 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KXL45972.1 - 1.3e-05 24.7 0.6 0.00014 21.4 0.1 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXL45972.1 - 0.0015 18.1 2.2 0.043 13.5 0.7 3.0 3 1 0 3 3 3 1 Thiolase, C-terminal domain KAsynt_C_assoc PF16197.5 KXL45972.1 - 0.058 13.9 0.0 0.17 12.3 0.0 1.9 2 0 0 2 2 2 0 Ketoacyl-synthetase C-terminal extension ACP_syn_III PF08545.10 KXL45972.1 - 0.069 13.0 3.0 5.6 6.9 0.0 3.2 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III NicO PF03824.16 KXL45973.1 - 1.5e-61 208.2 11.3 2.3e-61 207.6 11.3 1.2 1 0 0 1 1 1 1 High-affinity nickel-transport protein Ecl1 PF12855.7 KXL45974.1 - 2e-29 104.0 15.7 2e-29 104.0 15.7 1.9 3 0 0 3 3 3 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 KXL45974.1 - 0.0037 17.3 1.1 0.0095 16.0 1.1 1.6 1 0 0 1 1 1 1 MYND finger PLATZ PF04640.14 KXL45974.1 - 0.14 12.7 0.5 0.3 11.7 0.5 1.5 1 0 0 1 1 1 0 PLATZ transcription factor DUF2256 PF10013.9 KXL45974.1 - 2.1 8.5 5.6 1.5 9.0 1.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Epimerase PF01370.21 KXL45975.1 - 0.00036 20.1 0.0 0.00045 19.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PcF PF09461.10 KXL45975.1 - 0.16 12.3 0.1 0.3 11.5 0.1 1.4 1 0 0 1 1 1 0 Phytotoxin PcF protein YL1 PF05764.13 KXL45976.1 - 2.5e-38 132.6 33.6 2.5e-38 132.6 33.6 2.5 3 1 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.11 KXL45976.1 - 4.4e-07 29.5 0.0 8e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DUF3328 PF11807.8 KXL45977.1 - 7.4e-05 22.6 0.1 8.4e-05 22.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) PUF PF00806.19 KXL45979.1 - 1.6e-27 93.6 0.0 0.00014 21.3 0.0 6.2 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 KXL45979.1 - 8.1e-12 44.8 0.0 1.8e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.16 KXL45980.1 - 1.7e-24 86.4 23.2 1.7e-24 86.4 23.2 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL45980.1 - 8.8e-07 28.1 3.9 8.8e-07 28.1 3.9 2.7 2 1 0 3 3 3 1 Sugar (and other) transporter DUF2868 PF11067.8 KXL45980.1 - 0.038 13.5 0.2 0.064 12.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) LapA_dom PF06305.11 KXL45980.1 - 1 9.2 7.8 19 5.2 0.1 4.0 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF1751 PF08551.10 KXL45980.1 - 1.1 9.9 5.6 0.19 12.3 0.4 2.5 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) Methyltransf_16 PF10294.9 KXL45981.1 - 3.6e-21 75.7 0.0 5.5e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KXL45981.1 - 6.5e-06 25.8 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KXL45981.1 - 7.6e-05 22.2 0.0 9.3e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.16 KXL45981.1 - 0.00046 20.0 0.0 0.0014 18.4 0.0 1.7 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_25 PF13649.6 KXL45981.1 - 0.003 18.2 0.0 0.01 16.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 KXL45981.1 - 0.0068 15.5 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.19 KXL45981.1 - 0.023 14.4 0.0 0.036 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) LTV PF04180.14 KXL45981.1 - 0.067 12.9 0.1 3.5 7.3 0.1 2.0 2 0 0 2 2 2 0 Low temperature viability protein Ribosomal_S24e PF01282.19 KXL45982.1 - 3.3e-34 116.7 0.2 5e-34 116.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e AMPK1_CBM PF16561.5 KXL45983.1 - 1.8e-06 28.1 0.0 3.2e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Cwf_Cwc_15 PF04889.12 KXL45983.1 - 0.11 12.2 31.6 0.032 14.0 1.8 3.3 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein Vfa1 PF08432.10 KXL45983.1 - 10 6.4 11.9 10 6.4 4.1 2.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 GDNF PF02351.16 KXL45984.1 - 0.005 17.8 0.6 0.0057 17.6 0.6 1.1 1 0 0 1 1 1 1 GDNF/GAS1 domain RINGv PF12906.7 KXL45984.1 - 0.0083 16.2 1.0 0.025 14.7 0.4 1.8 2 0 0 2 2 2 1 RING-variant domain NACHT PF05729.12 KXL45987.1 - 4.1e-10 39.8 0.0 5.6e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.6 KXL45987.1 - 8.5e-06 25.8 0.0 1.4e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KXL45987.1 - 0.00016 21.7 0.0 0.00035 20.5 0.0 1.5 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KXL45987.1 - 0.00035 21.0 0.0 0.00052 20.4 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXL45987.1 - 0.00044 20.5 0.0 0.0006 20.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 KXL45987.1 - 0.0013 18.2 0.0 0.0022 17.5 0.0 1.4 2 0 0 2 2 2 1 Bacterial TniB protein NB-ARC PF00931.22 KXL45987.1 - 0.0019 17.4 0.5 0.015 14.5 0.5 2.1 1 1 0 1 1 1 1 NB-ARC domain AAA PF00004.29 KXL45987.1 - 0.0033 17.8 0.0 0.0078 16.6 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KXL45987.1 - 0.012 16.0 0.0 0.022 15.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 KXL45987.1 - 0.075 12.4 0.2 0.21 10.9 0.2 1.7 1 1 0 1 1 1 0 KaiC KAP_NTPase PF07693.14 KXL45987.1 - 0.081 12.2 0.0 0.15 11.3 0.0 1.4 1 1 1 2 2 2 0 KAP family P-loop domain protein_MS5 PF04776.12 KXL45987.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein MS5 AAA_24 PF13479.6 KXL45987.1 - 0.12 12.1 0.0 0.13 11.9 0.0 1.3 1 1 0 1 1 1 0 AAA domain L27 PF02828.16 KXL45987.1 - 0.14 11.9 0.1 1.3 8.9 0.0 2.2 1 1 1 2 2 2 0 L27 domain HET PF06985.11 KXL45988.1 - 1.4e-09 38.4 7.0 1.1e-06 29.0 1.3 2.2 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) PP2C PF00481.21 KXL45990.1 - 1.5e-38 132.9 0.0 2.2e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KXL45990.1 - 0.036 14.0 0.0 8 6.3 0.0 2.5 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) GAF_2 PF13185.6 KXL45990.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 GAF domain NUDIX PF00293.28 KXL45991.1 - 7.9e-22 77.7 0.0 8.7e-22 77.6 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain CN_hydrolase PF00795.22 KXL45992.1 - 1.9e-25 89.7 0.0 1.5e-24 86.7 0.0 1.9 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase GRDA PF04723.14 KXL45992.1 - 0.011 15.5 0.1 2.8 7.7 0.0 2.3 2 0 0 2 2 2 0 Glycine reductase complex selenoprotein A ThrE PF06738.12 KXL45992.1 - 0.15 11.5 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Putative threonine/serine exporter Amidohydro_1 PF01979.20 KXL45993.1 - 5.5e-20 72.0 0.0 4.2e-16 59.2 0.0 2.3 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KXL45993.1 - 9.3e-18 64.9 0.1 3.9e-09 36.5 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family Urease_alpha PF00449.20 KXL45993.1 - 0.06 13.7 0.5 0.1 12.9 0.5 1.4 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain EF-hand_1 PF00036.32 KXL45995.1 - 1.8e-16 58.4 5.1 3e-07 29.5 0.1 3.3 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KXL45995.1 - 5.7e-16 58.7 10.6 2e-11 44.2 0.7 2.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KXL45995.1 - 5.6e-15 53.9 3.8 6.8e-07 28.7 0.2 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 KXL45995.1 - 7.1e-12 45.0 2.8 7e-07 29.0 0.2 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 KXL45995.1 - 3.9e-06 27.1 0.0 7.7e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 KXL45995.1 - 2.6e-05 23.5 4.7 0.054 13.0 0.1 2.9 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.7 KXL45995.1 - 0.00062 19.7 0.0 0.056 13.4 0.0 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Methyltransf_3 PF01596.17 KXL45995.1 - 0.0037 16.5 0.1 0.0059 15.8 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase DUF4834 PF16118.5 KXL45995.1 - 0.0056 17.6 1.5 0.0089 17.0 1.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) Caleosin PF05042.13 KXL45995.1 - 0.071 13.0 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Caleosin related protein B5 PF03484.15 KXL45995.1 - 0.12 12.7 0.0 0.57 10.5 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetase B5 domain SPARC_Ca_bdg PF10591.9 KXL45995.1 - 0.17 12.2 0.6 0.82 10.0 0.3 1.9 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Casc1_N PF15927.5 KXL45995.1 - 7.4 6.2 12.8 11 5.6 12.8 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Pyr_redox_2 PF07992.14 KXL45996.1 - 1.6e-13 50.6 0.0 4.5e-10 39.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXL45996.1 - 4.1e-11 42.7 0.0 1.2e-10 41.2 0.0 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXL45996.1 - 4e-09 35.4 0.0 3.5e-08 32.4 0.0 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like DAO PF01266.24 KXL45996.1 - 1.8e-07 31.0 0.4 0.005 16.5 0.2 3.0 1 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXL45996.1 - 1.1e-06 29.1 0.0 0.026 15.1 0.0 2.8 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXL45996.1 - 1.3e-06 27.8 0.0 0.00015 21.0 0.0 2.7 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 KXL45996.1 - 2e-05 23.9 0.0 0.0003 20.0 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 KXL45996.1 - 0.00013 21.4 0.2 0.0013 18.1 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KXL45996.1 - 0.00057 19.0 0.0 0.0041 16.2 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KXL45996.1 - 0.00092 19.4 0.1 0.0031 17.7 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXL45996.1 - 0.0012 18.1 0.1 0.0055 16.0 0.1 2.0 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 KXL45996.1 - 0.0024 17.3 0.0 0.008 15.6 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXL45996.1 - 0.0027 16.5 0.0 0.0084 14.9 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein 2-Hacid_dh_C PF02826.19 KXL45996.1 - 0.016 14.6 0.3 4 6.8 0.1 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 KXL45996.1 - 0.049 12.7 1.7 0.27 10.3 0.0 2.7 3 1 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KXL45996.1 - 0.075 13.0 0.0 12 5.8 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KXL45996.1 - 0.082 11.7 0.3 9.1 5.0 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 KXL45996.1 - 0.11 11.8 0.1 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Arylsulfotran_2 PF14269.6 KXL45997.1 - 7e-41 140.5 0.3 1.1e-40 139.9 0.3 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXL45997.1 - 6.4e-16 58.2 0.4 4.4e-15 55.5 0.4 2.0 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Snf7 PF03357.21 KXL45998.1 - 5.7e-45 153.0 11.4 6.1e-45 152.9 11.4 1.0 1 0 0 1 1 1 1 Snf7 DUF3584 PF12128.8 KXL45998.1 - 0.0029 15.2 9.6 0.0039 14.8 9.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Zwint PF15556.6 KXL45998.1 - 0.0072 15.8 7.3 0.0094 15.5 7.3 1.3 1 0 0 1 1 1 1 ZW10 interactor Exonuc_VII_L PF02601.15 KXL45998.1 - 0.028 14.0 3.3 0.032 13.8 3.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit HSDR_N PF04313.14 KXL45998.1 - 0.03 14.3 2.2 0.048 13.6 2.2 1.3 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) CLZ PF16526.5 KXL45998.1 - 0.077 13.4 0.0 0.077 13.4 0.0 3.6 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NPV_P10 PF05531.12 KXL45998.1 - 0.11 13.0 7.9 2.6 8.6 0.8 3.3 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 KXL45998.1 - 0.4 10.7 9.6 3.1 7.8 0.1 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Allexi_40kDa PF05549.11 KXL45998.1 - 0.82 9.1 4.7 1.4 8.3 0.3 2.1 1 1 0 1 1 1 0 Allexivirus 40kDa protein FlaC_arch PF05377.11 KXL45998.1 - 1.3 9.5 10.8 4.5 7.8 0.0 3.6 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.6 KXL45998.1 - 3.7 6.8 10.1 5.9 6.1 10.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) GrpE PF01025.19 KXL45998.1 - 4.2 7.0 12.4 1.9 8.1 8.8 2.1 1 1 0 2 2 2 0 GrpE Atg14 PF10186.9 KXL45998.1 - 8.8 5.3 11.8 17 4.4 11.7 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cep57_CLD_2 PF14197.6 KXL45998.1 - 9.9 6.3 9.3 8.3 6.6 0.0 3.2 3 1 1 4 4 4 0 Centrosome localisation domain of PPC89 Aha1_N PF09229.11 KXL45999.1 - 8.4e-41 139.4 2.6 1.3e-40 138.8 2.6 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KXL45999.1 - 2.1e-18 66.7 0.4 3.8e-18 65.9 0.4 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 KXL45999.1 - 0.004 17.4 1.0 0.24 11.7 0.3 2.3 2 0 0 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport RRM_1 PF00076.22 KXL46001.1 - 7.4e-81 266.0 3.2 2.2e-21 75.4 0.1 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KXL46001.1 - 5.4e-28 97.0 2.4 5.4e-28 97.0 2.4 2.2 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 KXL46001.1 - 1.2e-14 54.0 0.1 0.0015 18.1 0.0 5.2 2 1 3 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXL46001.1 - 5.4e-09 35.8 0.1 0.0003 20.6 0.0 3.9 4 0 0 4 4 4 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KXL46001.1 - 0.00019 21.4 0.6 7.6 6.6 0.0 4.3 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif YflT PF11181.8 KXL46001.1 - 0.00038 20.9 8.8 0.011 16.2 0.9 3.4 4 0 0 4 4 4 2 Heat induced stress protein YflT RRM_3 PF08777.11 KXL46001.1 - 0.0008 19.4 11.5 0.11 12.6 2.9 4.7 4 2 1 5 5 5 2 RNA binding motif RRM_7 PF16367.5 KXL46001.1 - 0.0011 19.1 0.1 8.9 6.5 0.0 5.1 5 1 0 5 5 5 1 RNA recognition motif Limkain-b1 PF11608.8 KXL46001.1 - 0.0032 17.5 0.7 3.6 7.7 0.1 3.5 3 0 0 3 3 3 1 Limkain b1 OB_RNB PF08206.11 KXL46001.1 - 0.021 14.5 0.7 16 5.3 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain CbiG_mid PF11761.8 KXL46001.1 - 0.04 14.0 0.0 16 5.7 0.0 3.4 3 0 0 3 3 3 0 Cobalamin biosynthesis central region DUF809 PF05663.11 KXL46001.1 - 5.4 7.2 7.7 12 6.1 7.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF809) TMEM214 PF10151.9 KXL46001.1 - 9.4 4.5 7.4 14 3.9 7.4 1.2 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Transket_pyr PF02779.24 KXL46002.1 - 3.3e-63 212.6 0.0 6.4e-63 211.6 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KXL46002.1 - 3.7e-59 200.1 0.0 5.1e-59 199.7 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KXL46002.1 - 2.6e-56 189.5 0.0 4.2e-56 188.9 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KXL46002.1 - 6.6e-20 70.4 1.4 1.4e-19 69.4 1.4 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus GCFC PF07842.12 KXL46003.1 - 1.2e-75 254.6 8.5 2.8e-75 253.5 8.5 1.6 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 KXL46003.1 - 6.9e-17 61.1 3.1 1.5e-16 60.0 3.1 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KXL46003.1 - 2.5e-07 30.7 1.1 6.3e-07 29.4 1.1 1.7 1 0 0 1 1 1 1 G-patch domain 7TMR-HDED PF07697.11 KXL46003.1 - 2.2 8.4 6.7 5 7.2 6.7 1.6 1 1 0 1 1 1 0 7TM-HD extracellular BSD PF03909.17 KXL46006.1 - 3.8e-24 84.4 4.2 2.3e-14 53.1 0.3 2.6 2 0 0 2 2 2 2 BSD domain PH_TFIIH PF08567.11 KXL46006.1 - 1.2e-23 83.3 0.1 2.5e-23 82.2 0.1 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain FAM184 PF15665.5 KXL46006.1 - 0.0031 17.3 1.7 0.0065 16.3 1.7 1.5 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B Cauli_AT PF03233.13 KXL46006.1 - 0.015 15.3 1.0 0.038 13.9 0.2 2.0 2 0 0 2 2 2 0 Aphid transmission protein Interferon PF00143.19 KXL46006.1 - 0.025 14.7 2.2 0.083 13.1 0.1 2.6 3 0 0 3 3 3 0 Interferon alpha/beta domain GlutR_dimer PF00745.20 KXL46006.1 - 0.26 11.8 3.5 0.3 11.5 1.3 2.3 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain CysG_dimeriser PF10414.9 KXL46006.1 - 1.7 8.4 6.7 9.6 6.0 0.1 3.6 3 0 0 3 3 3 0 Sirohaem synthase dimerisation region FAD-oxidase_C PF02913.19 KXL46007.1 - 3.2e-26 92.5 1.3 1.5e-23 83.7 1.3 2.3 1 1 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KXL46007.1 - 1e-07 31.8 0.0 5.5e-07 29.4 0.0 2.2 2 1 0 2 2 2 1 FAD binding domain Aim21 PF11489.8 KXL46010.1 - 3.2e-158 528.8 87.0 4.4e-138 462.3 50.9 2.7 2 1 1 3 3 3 2 Altered inheritance of mitochondria protein 21 EzrA PF06160.12 KXL46015.1 - 0.1 10.7 4.8 1.1 7.4 0.8 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Iron_permease PF04120.12 KXL46016.1 - 5.4e-27 94.1 13.6 6.3e-17 61.6 0.1 4.1 4 0 0 4 4 4 4 Low affinity iron permease DUF3336 PF11815.8 KXL46017.1 - 5.6e-52 175.1 2.8 1.1e-51 174.2 2.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KXL46017.1 - 8.2e-18 65.3 1.3 2.3e-17 63.9 0.3 2.3 2 1 0 2 2 2 1 Patatin-like phospholipase Mpv17_PMP22 PF04117.12 KXL46018.1 - 3.3e-24 84.9 0.5 6.7e-24 83.9 0.5 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family NAPRTase PF04095.16 KXL46019.1 - 8.4e-53 179.4 0.1 2.6e-51 174.6 0.1 2.1 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 KXL46019.1 - 2.6e-36 124.8 0.0 3.9e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain SLT PF01464.20 KXL46020.1 - 0.00016 21.3 0.1 0.00028 20.5 0.1 1.5 1 0 0 1 1 1 1 Transglycosylase SLT domain PNKP_ligase PF16542.5 KXL46020.1 - 0.015 14.8 0.0 0.019 14.5 0.0 1.1 1 0 0 1 1 1 0 PNKP adenylyltransferase domain, ligase domain Lysozyme_like PF13702.6 KXL46020.1 - 0.018 14.7 0.7 0.047 13.4 0.3 1.8 1 1 0 1 1 1 0 Lysozyme-like Glucosaminidase PF01832.20 KXL46020.1 - 0.054 14.0 0.0 0.08 13.5 0.0 1.3 1 0 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase MtrH PF02007.18 KXL46020.1 - 0.069 12.2 0.1 0.092 11.8 0.1 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase MtrH subunit Iso_dh PF00180.20 KXL46021.1 - 1.4e-95 320.4 0.1 4e-95 318.9 0.1 1.6 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase TetR_C_31 PF17940.1 KXL46021.1 - 0.016 15.4 1.0 0.29 11.4 0.0 2.7 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain DUF1447 PF07288.11 KXL46021.1 - 0.17 12.0 0.2 0.32 11.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1447) RB_A PF01858.17 KXL46021.1 - 0.22 11.3 0.2 0.36 10.6 0.2 1.3 1 0 0 1 1 1 0 Retinoblastoma-associated protein A domain DUF1769 PF08588.10 KXL46022.1 - 9.6e-27 93.0 0.4 1.8e-26 92.1 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) CS PF04969.16 KXL46023.1 - 3.7e-18 66.3 0.2 6.6e-18 65.5 0.0 1.5 2 0 0 2 2 2 1 CS domain EthD PF07110.11 KXL46024.1 - 0.012 16.7 0.3 0.19 12.9 0.3 2.0 1 1 0 1 1 1 0 EthD domain ABM PF03992.16 KXL46025.1 - 0.009 16.1 0.0 0.027 14.6 0.0 1.8 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF3506 PF12014.8 KXL46026.1 - 8.1e-50 168.4 0.0 4.1e-49 166.2 0.0 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 KXL46026.1 - 3.6e-06 26.8 0.7 7.4e-06 25.8 0.7 1.6 1 0 0 1 1 1 1 F-box-like Elongin_A PF06881.11 KXL46026.1 - 0.00014 22.3 0.2 0.00041 20.8 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box PF00646.33 KXL46026.1 - 0.001 18.9 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KXL46026.1 - 0.098 12.5 0.2 0.27 11.1 0.2 1.7 1 0 0 1 1 1 0 F-box UbiA PF01040.18 KXL46027.1 - 1.4e-59 201.4 13.8 1.4e-59 201.4 13.8 1.5 1 1 1 2 2 2 1 UbiA prenyltransferase family PMBR PF09373.10 KXL46028.1 - 0.078 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Pseudomurein-binding repeat Peptidase_S9 PF00326.21 KXL46029.1 - 0.0032 17.0 0.0 0.05 13.1 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KXL46029.1 - 0.0043 16.7 0.0 1.9 8.1 0.1 3.0 2 1 1 3 3 3 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXL46029.1 - 0.0069 15.7 0.0 0.21 10.8 0.1 2.7 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 KXL46029.1 - 0.039 13.5 0.0 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) WD40 PF00400.32 KXL46030.1 - 1.7e-08 35.0 9.8 0.014 16.3 0.0 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat WD40 PF00400.32 KXL46031.1 - 7.4e-16 58.3 31.3 0.00035 21.3 0.3 11.9 13 1 0 13 13 13 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL46031.1 - 0.0067 16.7 0.0 2.1 8.7 0.0 4.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Rad4 PF03835.15 KXL46032.1 - 7.3e-16 58.2 0.4 1.5e-15 57.1 0.4 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 KXL46032.1 - 5.5e-12 46.1 1.9 1.3e-11 45.0 1.9 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Radial_spoke_3 PF06098.11 KXL46032.1 - 4.2 6.5 7.8 0.43 9.8 1.1 2.1 2 0 0 2 2 2 0 Radial spoke protein 3 Cupin_2 PF07883.11 KXL46033.1 - 1.4e-06 27.9 0.0 0.031 14.0 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.22 KXL46033.1 - 6.8e-05 22.5 0.0 9.7e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.7 KXL46033.1 - 0.041 13.6 0.1 0.098 12.4 0.1 1.8 1 1 0 1 1 1 0 Cupin Cupin_3 PF05899.12 KXL46033.1 - 0.14 11.8 0.0 0.83 9.4 0.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF861) DUF1708 PF08101.11 KXL46034.1 - 1e-162 542.2 0.0 1.7e-162 541.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) PRKCSH-like PF12999.7 KXL46035.1 - 0.16 11.8 1.3 0.2 11.4 0.3 1.7 2 0 0 2 2 2 0 Glucosidase II beta subunit-like MFS_1 PF07690.16 KXL46036.1 - 5.8e-43 147.2 57.6 4.6e-42 144.2 58.3 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXL46036.1 - 1.8e-22 79.5 18.0 3e-22 78.8 18.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXL46036.1 - 3.9e-14 52.4 14.1 3.9e-14 52.4 14.1 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter Oxidored_q2 PF00420.24 KXL46036.1 - 1.5 8.4 7.3 1.6 8.4 0.2 3.4 3 1 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L EF-hand_1 PF00036.32 KXL46037.1 - 1.2e-25 87.1 5.6 1.7e-07 30.3 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KXL46037.1 - 1.8e-21 74.2 4.0 0.00032 20.4 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KXL46037.1 - 2.2e-19 68.0 6.6 0.00045 19.6 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KXL46037.1 - 3e-19 68.6 3.8 2e-12 46.7 0.0 3.8 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_7 PF13499.6 KXL46037.1 - 3.5e-19 69.0 5.3 2.5e-10 40.6 0.1 3.2 3 0 0 3 3 3 3 EF-hand domain pair SRF-TF PF00319.18 KXL46038.1 - 6.2e-24 83.2 0.1 9.3e-24 82.7 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Dynamitin PF04912.14 KXL46039.1 - 6.4e-66 223.3 14.7 3.2e-64 217.7 14.7 2.0 1 1 0 1 1 1 1 Dynamitin DUF724 PF05266.14 KXL46039.1 - 0.00029 20.7 7.2 0.00041 20.2 0.1 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF724) Filament PF00038.21 KXL46039.1 - 0.011 15.4 6.0 0.11 12.1 0.6 2.3 2 0 0 2 2 2 0 Intermediate filament protein Cytochrom_B562 PF07361.11 KXL46039.1 - 0.029 15.0 4.1 1.9 9.2 0.1 3.4 2 1 1 3 3 3 0 Cytochrome b562 Rx_N PF18052.1 KXL46039.1 - 0.033 14.4 7.7 0.079 13.2 1.4 2.6 2 0 0 2 2 2 0 Rx N-terminal domain Tropomyosin_1 PF12718.7 KXL46039.1 - 0.039 14.1 10.2 0.18 11.9 2.4 2.5 2 0 0 2 2 2 0 Tropomyosin like DUF812 PF05667.11 KXL46039.1 - 0.062 12.2 5.4 0.47 9.3 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF812) DUF2046 PF09755.9 KXL46039.1 - 0.13 11.4 7.9 0.032 13.4 0.8 2.4 2 1 1 3 3 3 0 Uncharacterized conserved protein H4 (DUF2046) AOX PF01786.17 KXL46039.1 - 0.15 11.6 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Alternative oxidase ADIP PF11559.8 KXL46039.1 - 0.33 11.0 10.9 0.34 11.0 0.9 2.6 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 KXL46039.1 - 0.34 11.0 1.2 26 4.9 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DMPK_coil PF08826.10 KXL46039.1 - 0.35 11.0 11.0 2.8 8.1 2.2 2.8 2 0 0 2 2 2 0 DMPK coiled coil domain like DUF2408 PF10303.9 KXL46039.1 - 0.49 11.0 4.1 2.1 8.9 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) DUF4407 PF14362.6 KXL46039.1 - 0.79 9.0 9.9 2.4 7.4 2.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 KXL46039.1 - 0.86 8.6 3.5 6.7 5.7 0.3 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FlaC_arch PF05377.11 KXL46039.1 - 0.88 10.0 6.3 19 5.8 0.3 3.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Prefoldin_2 PF01920.20 KXL46039.1 - 1.1 9.2 10.4 4.2 7.4 0.3 2.7 3 0 0 3 3 2 0 Prefoldin subunit Not3 PF04065.15 KXL46039.1 - 1.3 8.4 5.0 0.36 10.2 0.5 2.1 2 1 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component Spc7 PF08317.11 KXL46039.1 - 1.4 7.7 10.2 3.7 6.4 0.6 2.4 2 1 0 2 2 2 0 Spc7 kinetochore protein DUF2203 PF09969.9 KXL46039.1 - 2 9.1 8.7 9 7.0 0.7 3.0 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Ax_dynein_light PF10211.9 KXL46039.1 - 2.2 8.2 8.4 0.66 9.9 2.3 2.5 2 0 0 2 2 2 0 Axonemal dynein light chain SOGA PF11365.8 KXL46039.1 - 2.2 9.4 7.8 20 6.4 0.1 3.0 3 0 0 3 3 2 0 Protein SOGA DUF5320 PF17253.2 KXL46039.1 - 2.3 9.4 6.5 0.94 10.6 1.8 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Laminin_II PF06009.12 KXL46039.1 - 2.4 8.2 9.8 0.42 10.6 0.9 3.5 3 1 1 4 4 4 0 Laminin Domain II DUF4140 PF13600.6 KXL46039.1 - 3.4 8.2 11.6 3 8.4 2.6 3.4 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) CLZ PF16526.5 KXL46039.1 - 3.9 7.9 11.7 1.8 9.0 1.3 3.9 2 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spc24 PF08286.11 KXL46039.1 - 4.3 7.6 10.0 2.8 8.2 0.5 3.1 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 DUF4337 PF14235.6 KXL46039.1 - 4.4 7.4 8.8 1.8 8.7 1.5 2.7 3 0 0 3 3 2 0 Domain of unknown function (DUF4337) PRKG1_interact PF15898.5 KXL46039.1 - 4.5 8.2 12.3 9.5 7.2 0.7 3.4 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain DivIC PF04977.15 KXL46039.1 - 6.4 6.6 11.0 2.3 8.1 0.5 2.8 3 0 0 3 3 2 0 Septum formation initiator TRAF_BIRC3_bd PF16673.5 KXL46039.1 - 7.1 6.5 8.3 0.7 9.7 1.6 2.5 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain APG6_N PF17675.1 KXL46039.1 - 7.5 7.1 17.5 7.1 7.2 2.0 3.0 2 1 0 2 2 2 0 Apg6 coiled-coil region GAS PF13851.6 KXL46039.1 - 8.2 5.7 9.3 1.9 7.8 0.6 2.5 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding DHHC PF01529.20 KXL46040.1 - 1.1e-29 103.2 11.2 1.1e-29 103.2 11.2 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase IGFBP PF00219.18 KXL46040.1 - 0.65 10.7 6.5 1.2 9.8 6.5 1.4 1 0 0 1 1 1 0 Insulin-like growth factor binding protein Pkinase PF00069.25 KXL46041.1 - 2.6e-65 220.4 0.3 3e-65 220.2 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL46041.1 - 5.8e-19 68.4 0.0 8.1e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXL46041.1 - 2.6e-07 30.8 0.0 1.9e-05 24.7 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXL46041.1 - 0.0047 16.3 0.0 0.0061 15.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXL46041.1 - 0.0048 15.7 0.0 0.0087 14.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXL46041.1 - 0.01 15.2 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KXL46041.1 - 0.036 13.6 0.2 0.036 13.6 0.2 2.0 3 0 0 3 3 3 0 Choline/ethanolamine kinase tRNA-synt_1 PF00133.22 KXL46042.1 - 1.9e-211 703.5 0.0 1.9e-210 700.2 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KXL46042.1 - 3.1e-32 111.6 0.2 8.1e-32 110.3 0.2 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KXL46042.1 - 1.2e-14 53.9 0.3 1.8e-06 27.0 0.0 4.8 3 2 1 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KXL46042.1 - 9.4e-10 38.3 3.6 6.7e-07 29.0 0.0 2.8 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 KXL46042.1 - 0.038 13.3 1.8 0.5 9.7 0.0 2.8 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain PepSY PF03413.19 KXL46042.1 - 0.66 10.6 0.0 0.66 10.6 0.0 2.8 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain Abhydrolase_6 PF12697.7 KXL46043.1 - 4.9e-20 73.1 0.2 6.9e-20 72.6 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXL46043.1 - 1.3e-06 28.3 0.1 3.3e-06 27.0 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXL46043.1 - 0.0044 16.3 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Sial-lect-inser PF09264.10 KXL46043.1 - 0.016 15.0 0.0 0.097 12.4 0.0 2.0 2 0 0 2 2 2 0 Vibrio cholerae sialidase, lectin insertion Thioesterase PF00975.20 KXL46043.1 - 0.12 12.4 0.6 1 9.4 0.5 2.2 1 1 0 1 1 1 0 Thioesterase domain Pap_E4 PF02711.14 KXL46043.1 - 0.15 13.1 2.6 0.3 12.1 2.6 1.4 1 0 0 1 1 1 0 E4 protein Fcf1 PF04900.12 KXL46044.1 - 6.5e-34 116.3 0.1 9.8e-34 115.7 0.1 1.3 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 KXL46044.1 - 0.0021 18.4 0.0 0.0042 17.4 0.0 1.5 1 0 0 1 1 1 1 PIN like domain DUF726 PF05277.12 KXL46045.1 - 1.1e-121 405.9 3.9 1.6e-121 405.5 3.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Toxin_15 PF07906.13 KXL46045.1 - 0.097 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 ShET2 enterotoxin, N-terminal region Dabb PF07876.12 KXL46046.1 - 0.00015 22.3 0.1 0.0012 19.4 0.1 2.0 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF3659 PF12396.8 KXL46047.1 - 2.1e-278 898.7 187.6 4.5e-22 77.7 3.0 16.0 16 0 0 16 16 16 14 Protein of unknown function (DUF3659) GCV_T_C PF08669.11 KXL46047.1 - 0.0028 17.5 0.6 37 4.3 0.0 6.3 5 1 0 5 5 5 1 Glycine cleavage T-protein C-terminal barrel domain RPW8 PF05659.11 KXL46047.1 - 0.65 9.7 1.7 2.9 7.6 0.6 2.2 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF1246 PF06849.12 KXL46048.1 - 0.038 14.0 0.1 0.98 9.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1246) PRIMA1 PF16101.5 KXL46048.1 - 0.64 10.1 12.7 1.3 9.1 12.7 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 KXL46048.1 - 0.72 9.3 8.2 1.3 8.4 8.2 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal IQ PF00612.27 KXL46049.1 - 0.0054 16.4 0.8 0.011 15.4 0.8 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif KGG PF10685.9 KXL46049.1 - 1.6 9.1 0.1 1.6 9.1 0.1 3.0 4 0 0 4 4 4 0 Stress-induced bacterial acidophilic repeat motif HTH_32 PF13565.6 KXL46050.1 - 6.9e-08 33.0 0.6 6.9e-08 33.0 0.6 4.0 4 0 0 4 4 4 1 Homeodomain-like domain HTH_36 PF13730.6 KXL46050.1 - 0.00015 21.7 0.0 0.00074 19.4 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 KXL46050.1 - 0.00017 21.5 0.5 0.00017 21.5 0.5 2.3 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_1 PF01527.20 KXL46050.1 - 0.015 15.6 0.1 0.046 14.0 0.1 1.8 1 0 0 1 1 1 0 Transposase HTH_Tnp_IS630 PF01710.16 KXL46050.1 - 0.046 13.8 0.0 0.16 12.1 0.0 1.9 1 0 0 1 1 1 0 Transposase MerR PF00376.23 KXL46050.1 - 3.7 7.4 4.9 1.3 8.9 1.0 2.3 2 1 0 2 2 2 0 MerR family regulatory protein BAH PF01426.18 KXL46051.1 - 2.3e-17 63.0 0.2 5.2e-17 61.8 0.2 1.6 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H_2 PF13832.6 KXL46051.1 - 2.8e-17 62.9 1.2 2.8e-17 62.9 1.2 4.3 5 0 0 5 5 5 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KXL46051.1 - 7.1e-14 51.8 2.2 7.1e-14 51.8 2.2 5.1 5 1 1 6 6 6 3 PHD-like zinc-binding domain PHD PF00628.29 KXL46051.1 - 8e-11 41.7 56.8 3.8e-06 26.7 10.1 6.5 7 0 0 7 7 7 3 PHD-finger PHD_2 PF13831.6 KXL46051.1 - 5e-05 22.8 1.6 5e-05 22.8 1.6 5.9 6 0 0 6 6 6 1 PHD-finger C1_1 PF00130.22 KXL46051.1 - 0.78 9.7 44.4 0.027 14.4 5.4 5.2 5 0 0 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 KXL46051.1 - 0.93 9.6 39.6 0.014 15.5 5.4 5.4 6 0 0 6 6 6 0 PHD-finger Dus PF01207.17 KXL46052.1 - 8.3e-47 159.8 0.1 3.6e-46 157.7 0.0 1.9 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) IFRD_C PF04836.12 KXL46052.1 - 0.17 12.5 0.7 0.38 11.4 0.7 1.5 1 0 0 1 1 1 0 Interferon-related protein conserved region 2-Hacid_dh_C PF02826.19 KXL46053.1 - 3.6e-41 140.5 0.0 5.8e-26 90.9 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXL46053.1 - 0.021 14.5 0.0 0.023 14.4 0.0 1.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3HCDH_N PF02737.18 KXL46053.1 - 0.33 10.8 1.2 0.54 10.1 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Alpha-L-AF_C PF06964.12 KXL46055.1 - 1.3e-24 87.2 0.0 4e-24 85.6 0.0 1.7 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminal domain CBM_4_9 PF02018.17 KXL46055.1 - 0.0025 18.1 2.7 0.0027 18.0 0.9 2.0 2 1 0 2 2 2 1 Carbohydrate binding domain Peptidase_M75 PF09375.10 KXL46055.1 - 0.095 12.2 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Imelysin Sin3a_C PF16879.5 KXL46056.1 - 1.8e-64 218.2 1.2 5e-63 213.5 0.0 3.3 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein PAH PF02671.21 KXL46056.1 - 1e-43 147.2 3.5 1.5e-16 60.2 2.6 4.2 3 1 1 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 KXL46056.1 - 3.5e-40 136.0 0.5 2.2e-39 133.5 0.0 2.4 2 0 0 2 2 2 1 Sin3 family co-repressor dCMP_cyt_deam_1 PF00383.23 KXL46057.1 - 2.2e-23 82.1 0.0 3e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXL46057.1 - 1.9e-19 69.8 0.0 2.4e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 KXL46057.1 - 3.1e-05 24.1 2.1 0.034 14.2 2.1 2.3 1 1 0 1 1 1 1 Bd3614-like deaminase SNAD4 PF18750.1 KXL46057.1 - 0.00052 20.1 0.0 0.002 18.2 0.0 1.8 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC_N PF08210.11 KXL46057.1 - 0.0013 18.7 0.1 0.0093 15.9 0.1 1.9 1 1 0 1 1 1 1 APOBEC-like N-terminal domain NAD1 PF18778.1 KXL46057.1 - 0.002 18.2 0.0 0.0098 16.0 0.0 1.9 1 1 0 1 1 1 1 Novel AID APOBEC clade 1 NAD2 PF18782.1 KXL46057.1 - 0.0021 18.2 0.0 0.0059 16.7 0.0 1.7 1 1 0 1 1 1 1 Novel AID APOBEC clade 2 APOBEC2 PF18772.1 KXL46057.1 - 0.0024 17.9 0.0 0.015 15.3 0.0 1.9 1 1 0 1 1 1 1 APOBEC2 XOO_2897-deam PF14440.6 KXL46057.1 - 0.012 15.7 0.3 0.028 14.5 0.1 1.7 1 1 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase DUF3725 PF12523.8 KXL46057.1 - 0.027 14.8 0.0 0.042 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3725) URO-D PF01208.17 KXL46058.1 - 2.8e-125 418.0 0.0 3.2e-125 417.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) MutS_V PF00488.21 KXL46059.1 - 8.4e-73 244.4 0.0 1.4e-72 243.7 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXL46059.1 - 4.9e-40 137.8 4.6 8.5e-40 137.0 4.6 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KXL46059.1 - 6.2e-20 71.5 0.0 1.5e-19 70.3 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KXL46059.1 - 1.7e-06 28.4 0.0 4.7e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 MutS domain II AAA_14 PF13173.6 KXL46059.1 - 0.0027 17.7 0.0 0.11 12.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 KXL46059.1 - 0.043 13.4 0.0 0.09 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXL46059.1 - 0.11 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KXL46059.1 - 0.13 12.8 0.1 0.31 11.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain Myosin_head PF00063.21 KXL46060.1 - 2.6e-246 819.1 7.1 3.1e-246 818.9 7.1 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KXL46060.1 - 3.4e-51 173.6 0.0 6.8e-51 172.6 0.0 1.6 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 KXL46060.1 - 3.9e-14 52.0 0.1 7.6e-14 51.1 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXL46060.1 - 4.7e-11 42.4 0.0 1.1e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXL46060.1 - 1.2e-07 31.3 0.0 3.4e-07 29.8 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain IQ PF00612.27 KXL46060.1 - 0.022 14.5 7.3 1.8 8.6 2.1 2.8 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_16 PF13191.6 KXL46060.1 - 0.031 14.7 0.0 0.14 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KXL46060.1 - 0.049 13.9 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 KXL46060.1 - 0.071 12.6 3.3 7.6 6.0 0.0 3.1 3 0 0 3 3 3 0 HPr Serine kinase C-terminal domain NACHT PF05729.12 KXL46060.1 - 0.1 12.5 0.0 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 NACHT domain DUF3602 PF12223.8 KXL46061.1 - 8.9e-19 67.9 12.3 1.7e-16 60.5 5.0 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) Mito_carr PF00153.27 KXL46062.1 - 7.7e-47 157.2 6.5 1.8e-16 59.8 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein CBS PF00571.28 KXL46063.1 - 0.0016 18.8 0.0 2 9.0 0.0 2.9 2 1 0 2 2 2 2 CBS domain Zip PF02535.22 KXL46064.1 - 4.6e-50 170.7 0.1 6.1e-50 170.3 0.1 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter DUF1746 PF08508.10 KXL46065.1 - 4.3e-40 136.6 0.1 6.6e-40 136.0 0.1 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) Kinase-PolyVal PF18762.1 KXL46065.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins DUF4187 PF13821.6 KXL46066.1 - 2.5e-20 72.0 1.7 5.6e-20 70.9 1.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 KXL46066.1 - 1.2e-11 44.2 2.2 2.1e-11 43.5 2.2 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KXL46066.1 - 0.0095 16.0 1.4 0.027 14.5 1.4 1.8 1 0 0 1 1 1 1 G-patch domain FMN_red PF03358.15 KXL46067.1 - 6.1e-08 32.6 0.0 8.3e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KXL46067.1 - 0.00017 21.4 0.0 0.00022 21.0 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 KXL46067.1 - 0.0011 19.2 0.0 0.044 14.0 0.0 2.3 1 1 0 1 1 1 1 Flavodoxin F_actin_cap_B PF01115.17 KXL46068.1 - 2e-92 309.1 0.0 2.3e-92 309.0 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Pkinase PF00069.25 KXL46069.1 - 8.1e-60 202.4 0.0 1.1e-59 202.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL46069.1 - 3.5e-43 147.7 0.0 5.5e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 KXL46069.1 - 1.9e-09 37.6 0.0 3.9e-05 23.8 0.0 2.7 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 KXL46069.1 - 3.4e-08 33.2 0.0 5.6e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXL46069.1 - 0.012 14.4 0.0 0.024 13.4 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KXL46069.1 - 0.018 14.4 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXL46069.1 - 0.037 13.9 0.0 0.091 12.7 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Thioredoxin_4 PF13462.6 KXL46070.1 - 1.2e-07 32.0 0.0 4.4e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin TMEM234 PF10639.9 KXL46071.1 - 6.1e-36 123.0 0.6 2e-35 121.3 0.6 1.7 1 1 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 KXL46071.1 - 0.00019 21.6 9.3 0.027 14.6 6.3 2.3 2 1 0 2 2 2 2 EamA-like transporter family PhyH PF05721.13 KXL46072.1 - 2.8e-54 184.6 0.0 3.4e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Zn_clus PF00172.18 KXL46073.1 - 4.5e-09 36.3 12.6 8.7e-09 35.4 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXL46074.1 - 4.9e-14 52.0 0.0 7.4e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL46074.1 - 5.7e-11 42.4 10.1 1.2e-10 41.3 10.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC2_membrane PF01061.24 KXL46076.1 - 7.3e-31 107.2 29.4 1.1e-30 106.7 29.4 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KXL46076.1 - 9e-27 94.3 0.1 1.6e-26 93.5 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXL46076.1 - 3.8e-07 30.2 0.5 0.027 14.3 0.0 2.5 2 1 0 3 3 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KXL46076.1 - 1.4e-06 28.3 0.1 0.00017 21.6 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KXL46076.1 - 6.6e-06 26.6 0.3 1.4e-05 25.5 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXL46076.1 - 4.3e-05 23.8 0.2 0.00052 20.3 0.2 2.5 1 1 1 2 2 2 1 AAA domain SMC_N PF02463.19 KXL46076.1 - 0.00011 21.7 0.0 0.0032 16.9 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 KXL46076.1 - 0.00019 21.1 0.1 0.00038 20.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KXL46076.1 - 0.00093 18.9 0.2 0.0019 17.9 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 KXL46076.1 - 0.0019 18.0 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_23 PF13476.6 KXL46076.1 - 0.0035 17.9 0.0 0.0069 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KXL46076.1 - 0.0037 17.5 0.0 0.0067 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KXL46076.1 - 0.0046 17.0 0.3 0.018 15.1 0.1 1.9 2 1 0 2 2 1 1 50S ribosome-binding GTPase AAA_13 PF13166.6 KXL46076.1 - 0.0078 14.9 0.1 0.15 10.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KXL46076.1 - 0.0086 15.2 0.1 0.016 14.3 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 KXL46076.1 - 0.0092 15.7 0.1 0.016 14.9 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KXL46076.1 - 0.0094 16.4 0.0 0.085 13.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KXL46076.1 - 0.011 15.6 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 KXL46076.1 - 0.021 15.4 0.0 0.046 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KXL46076.1 - 0.023 14.3 0.3 0.053 13.1 0.3 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 KXL46076.1 - 0.029 14.4 0.0 0.23 11.5 0.1 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KXL46076.1 - 0.047 13.4 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXL46076.1 - 0.058 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 KXL46076.1 - 0.089 12.7 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_35 PF14516.6 KXL46076.1 - 0.098 11.5 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain RNA_helicase PF00910.22 KXL46076.1 - 0.1 13.0 0.0 0.33 11.4 0.0 1.9 1 0 0 1 1 1 0 RNA helicase GTP_EFTU PF00009.27 KXL46076.1 - 0.12 11.9 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Roc PF08477.13 KXL46076.1 - 0.12 12.5 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 KXL46076.1 - 0.13 12.1 0.1 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.6 KXL46076.1 - 0.15 12.1 0.0 0.43 10.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain Cytidylate_kin PF02224.18 KXL46076.1 - 0.15 11.7 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase SRP54 PF00448.22 KXL46076.1 - 0.16 11.6 0.2 0.33 10.6 0.2 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 KXL46076.1 - 0.17 11.6 0.2 0.44 10.3 0.2 1.7 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein PDR_assoc PF08370.11 KXL46076.1 - 0.19 11.5 0.1 0.19 11.5 0.1 3.4 3 0 0 3 3 3 0 Plant PDR ABC transporter associated Lactamase_B PF00753.27 KXL46078.1 - 1.8e-15 57.5 5.6 2.2e-15 57.2 5.6 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXL46078.1 - 0.0032 17.0 1.7 0.004 16.7 0.9 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain zf-CCHC PF00098.23 KXL46080.1 - 1e-27 94.9 108.7 3.2e-06 27.0 0.7 12.1 13 0 0 13 13 13 8 Zinc knuckle zf-CCHC_2 PF13696.6 KXL46080.1 - 6.5e-08 32.3 85.2 0.00093 19.0 0.6 10.5 11 0 0 11 11 11 8 Zinc knuckle zf-CCHC_4 PF14392.6 KXL46080.1 - 0.00012 21.7 67.1 0.09 12.5 1.7 9.5 9 1 1 10 10 10 7 Zinc knuckle zf-CCHC_6 PF15288.6 KXL46080.1 - 0.005 16.6 0.4 0.005 16.6 0.4 10.1 10 1 0 10 10 10 4 Zinc knuckle GCV_T PF01571.21 KXL46080.1 - 0.12 11.7 0.3 0.27 10.6 0.3 1.6 1 1 0 1 1 1 0 Aminomethyltransferase folate-binding domain zf-CCHC_3 PF13917.6 KXL46080.1 - 2.3 8.2 72.4 0.91 9.5 0.2 9.9 2 2 7 9 9 9 0 Zinc knuckle Chitin_synth_1 PF01644.17 KXL46081.1 - 2.7e-74 248.6 0.2 4e-74 248.0 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KXL46081.1 - 8e-30 102.6 0.0 1.5e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KXL46081.1 - 4.4e-20 71.8 4.3 1.9e-16 59.8 0.0 3.0 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KXL46081.1 - 4.8e-07 29.9 15.1 4.8e-06 26.6 15.1 2.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXL46081.1 - 0.0048 16.8 0.0 0.016 15.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Ten_N PF06484.12 KXL46082.1 - 0.11 12.4 0.0 0.12 12.2 0.0 1.0 1 0 0 1 1 1 0 Teneurin Intracellular Region Med1 PF10744.9 KXL46083.1 - 1.8e-66 224.9 0.0 2.6e-66 224.4 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Forkhead PF00250.18 KXL46084.1 - 2.2e-18 66.3 0.0 4.3e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KXL46084.1 - 0.0079 16.5 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain Sec1 PF00995.23 KXL46085.1 - 1.6e-127 427.2 0.0 1.8e-127 427.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family APG6_N PF17675.1 KXL46085.1 - 1.7 9.2 6.5 11 6.6 5.8 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region zf_CCCH_4 PF18345.1 KXL46086.1 - 1.1e-07 31.7 2.8 1.9e-07 30.9 2.8 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 KXL46086.1 - 2.2e-06 27.3 0.8 3.8e-06 26.6 0.8 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 KXL46086.1 - 2.9e-05 23.9 1.3 4.7e-05 23.2 1.3 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KXL46086.1 - 0.00069 20.3 0.4 0.0025 18.5 0.4 1.9 1 0 0 1 1 1 1 Torus domain zf-CCCH_3 PF15663.5 KXL46086.1 - 0.12 12.6 0.7 0.28 11.4 0.7 1.6 1 0 0 1 1 1 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 KXL46086.1 - 0.14 12.6 0.4 0.25 11.9 0.4 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger GFO_IDH_MocA PF01408.22 KXL46087.1 - 4.8e-06 27.4 0.0 1.2e-05 26.2 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold SAF PF08666.12 KXL46087.1 - 8.2e-06 26.4 0.0 1.8e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 SAF domain NAD_binding_3 PF03447.16 KXL46087.1 - 5.2e-05 23.9 0.0 0.00035 21.2 0.0 2.3 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 KXL46087.1 - 0.044 14.1 0.0 0.23 11.8 0.0 2.3 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Transthyretin PF00576.21 KXL46088.1 - 2.3e-33 115.2 0.0 2.8e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family Zn_clus PF00172.18 KXL46089.1 - 1.7 8.8 11.4 0.82 9.8 8.7 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KXL46090.1 - 0.019 13.8 0.1 0.02 13.8 0.1 1.0 1 0 0 1 1 1 0 Sugar (and other) transporter RRM_1 PF00076.22 KXL46091.1 - 2.8e-45 152.0 0.0 6.1e-17 61.2 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXL46091.1 - 7.6e-05 22.8 0.3 0.042 14.0 0.0 3.2 3 1 0 3 3 3 1 RNA recognition motif RRM_3 PF08777.11 KXL46091.1 - 8.9e-05 22.5 0.0 0.00099 19.1 0.0 2.4 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.6 KXL46091.1 - 9.4e-05 22.3 0.0 0.0013 18.7 0.0 2.6 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KXL46091.1 - 0.00014 21.6 0.0 0.046 13.6 0.0 2.9 3 0 0 3 3 3 1 Occluded RNA-recognition motif PHM7_cyt PF14703.6 KXL46091.1 - 0.0026 18.0 0.2 0.79 9.9 0.0 3.5 3 1 1 4 4 4 1 Cytosolic domain of 10TM putative phosphate transporter OB_RNB PF08206.11 KXL46091.1 - 0.013 15.2 0.1 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain RRM_5 PF13893.6 KXL46091.1 - 0.025 14.2 0.0 0.1 12.2 0.0 1.9 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IMUP PF15761.5 KXL46092.1 - 0.61 10.8 5.8 0.83 10.4 5.8 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein PCI PF01399.27 KXL46093.1 - 8.9e-05 23.0 0.0 0.00018 22.0 0.0 1.6 1 0 0 1 1 1 1 PCI domain CSN7a_helixI PF18392.1 KXL46093.1 - 0.00035 20.4 0.7 0.00053 19.8 0.7 1.3 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain Histone_HNS PF00816.21 KXL46093.1 - 0.1 13.4 0.8 0.26 12.1 0.6 1.8 2 0 0 2 2 2 0 H-NS histone family DUF236 PF03057.14 KXL46093.1 - 0.18 11.8 0.3 0.35 10.9 0.3 1.4 1 0 0 1 1 1 0 DUF236 repeat Redoxin PF08534.10 KXL46094.1 - 1.7e-15 57.0 0.0 2.2e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KXL46094.1 - 6.4e-07 29.3 0.0 4.6e-05 23.3 0.0 2.1 2 0 0 2 2 2 2 AhpC/TSA family E1-E2_ATPase PF00122.20 KXL46095.1 - 1.1e-49 168.4 0.4 1.1e-49 168.4 0.4 2.1 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.26 KXL46095.1 - 9.9e-45 150.8 3.6 4e-12 46.4 0.0 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 KXL46095.1 - 9e-38 130.7 0.3 4.2e-37 128.5 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KXL46095.1 - 0.0044 16.8 0.9 0.008 15.9 0.2 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase EccE PF11203.8 KXL46095.1 - 0.08 13.3 0.5 8.9 6.7 0.1 3.5 3 0 0 3 3 3 0 Putative type VII ESX secretion system translocon, EccE Rimk_N PF18030.1 KXL46095.1 - 0.12 12.8 0.0 7.1 7.1 0.0 3.5 4 0 0 4 4 4 0 RimK PreATP-grasp domain DUF1884 PF08967.10 KXL46095.1 - 0.15 12.3 0.2 13 6.1 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1884) Lactamase_B_3 PF13483.6 KXL46096.1 - 0.0013 18.6 0.1 0.0046 16.9 0.1 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF2733 PF10813.8 KXL46098.1 - 0.71 9.7 4.4 0.58 10.0 2.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2733) Pyr_redox_2 PF07992.14 KXL46100.1 - 2.6e-45 154.9 0.7 3.5e-45 154.5 0.7 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 KXL46100.1 - 1.7e-16 59.9 0.0 4.4e-16 58.6 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 KXL46100.1 - 2.6e-14 53.5 0.7 2.2e-13 50.5 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 KXL46100.1 - 2.3e-06 27.4 0.0 1.7e-05 24.7 0.0 2.4 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Pyr_redox_3 PF13738.6 KXL46100.1 - 3.2e-05 23.3 0.1 0.00052 19.4 0.0 2.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 KXL46100.1 - 0.0045 17.5 0.0 0.013 16.1 0.0 1.8 1 0 0 1 1 1 1 Reductase C-terminal UDPG_MGDP_dh_N PF03721.14 KXL46100.1 - 0.032 13.8 0.1 0.068 12.7 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 KXL46100.1 - 0.056 13.3 0.2 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 KXL46100.1 - 0.1 11.5 0.6 0.16 10.8 0.0 1.5 2 0 0 2 2 2 0 Tryptophan halogenase WD40 PF00400.32 KXL46101.1 - 1.7e-16 60.3 3.6 0.00067 20.4 0.2 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL46101.1 - 9.5e-10 38.7 0.0 1e-06 28.9 0.0 4.3 3 3 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXL46101.1 - 0.00078 19.4 0.1 2.3 8.1 0.0 3.1 3 0 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A RNA_pol_Rpb1_1 PF04997.12 KXL46102.1 - 1.5e-108 362.8 0.0 2.7e-108 362.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KXL46102.1 - 3.6e-100 334.8 0.0 6.2e-100 334.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KXL46102.1 - 8.2e-75 250.6 0.1 2.5e-74 249.0 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 KXL46102.1 - 6.5e-55 185.9 0.0 1.2e-54 185.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 KXL46102.1 - 1.4e-43 148.1 2.8 2.6e-43 147.2 2.8 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 KXL46102.1 - 6.9e-43 146.3 0.0 1.2e-42 145.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KXL46102.1 - 1.8e-34 117.9 0.0 4.3e-34 116.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 KXL46102.1 - 2.3e-18 65.5 243.8 0.0038 17.5 12.3 16.8 9 4 7 19 19 19 15 RNA polymerase Rpb1 C-terminal repeat zf-C4pol PF14260.6 KXL46102.1 - 0.23 12.0 0.4 0.51 10.8 0.4 1.6 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta SBF PF01758.16 KXL46104.1 - 1.9e-48 164.8 3.5 1.9e-48 164.8 3.5 2.0 2 0 0 2 2 2 1 Sodium Bile acid symporter family PIG-P PF08510.12 KXL46104.1 - 5.3 7.0 7.2 11 6.0 0.3 2.9 2 1 0 2 2 2 0 PIG-P PTR2 PF00854.21 KXL46105.1 - 1.8e-62 211.5 4.7 2.4e-62 211.1 4.7 1.2 1 0 0 1 1 1 1 POT family Caps_synth_CapC PF14102.6 KXL46105.1 - 0.12 12.8 0.3 0.12 12.8 0.3 3.2 4 0 0 4 4 4 0 Capsule biosynthesis CapC Mei5 PF10376.9 KXL46106.1 - 0.015 15.2 8.5 0.0097 15.8 4.2 2.6 2 1 0 2 2 2 0 Double-strand recombination repair protein U1snRNP70_N PF12220.8 KXL46106.1 - 0.028 15.1 1.3 0.089 13.4 1.3 1.8 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Cu_amine_oxid PF01179.20 KXL46107.1 - 5.9e-117 391.0 1.9 7.3e-117 390.7 1.9 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 KXL46107.1 - 1.4e-21 76.0 0.1 4.5e-21 74.4 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) tRNA-synt_2 PF00152.20 KXL46108.1 - 1.1e-60 205.4 0.0 1.3e-60 205.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KXL46108.1 - 1.2e-12 47.7 0.0 2.2e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KXL46108.1 - 6.7e-05 22.5 0.0 0.033 13.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF5134 PF17197.4 KXL46109.1 - 0.025 14.5 0.5 0.025 14.5 0.5 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF5134) DUF5337 PF17272.2 KXL46109.1 - 0.031 14.1 1.6 0.11 12.3 1.6 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5337) TerC PF03741.16 KXL46109.1 - 0.17 11.5 10.3 0.047 13.4 4.9 2.5 1 1 1 2 2 2 0 Integral membrane protein TerC family EMP24_GP25L PF01105.24 KXL46109.1 - 0.22 11.4 0.3 0.53 10.2 0.3 1.7 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF997 PF06196.12 KXL46109.1 - 4.6 7.3 16.4 0.35 10.9 3.5 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF997) RhoGEF PF00621.20 KXL46110.1 - 1.9e-15 57.6 0.0 7.7e-15 55.6 0.0 2.0 1 1 0 1 1 1 1 RhoGEF domain AMPK1_CBM PF16561.5 KXL46114.1 - 9.4e-06 25.8 0.0 1.8e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Scytalone_dh PF02982.14 KXL46116.1 - 7.6e-84 279.3 2.1 8.5e-84 279.2 2.1 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 KXL46116.1 - 1.2e-07 31.9 0.5 1.6e-07 31.5 0.5 1.1 1 0 0 1 1 1 1 SnoaL-like domain LPD23 PF18838.1 KXL46116.1 - 0.01 15.6 0.4 0.021 14.6 0.4 1.5 1 0 0 1 1 1 0 Large polyvalent protein associated domain 23 HNOB PF07700.15 KXL46116.1 - 0.011 15.7 0.0 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 Haem-NO-binding ADIP PF11559.8 KXL46117.1 - 2e-30 105.9 4.6 2e-30 105.9 4.6 2.4 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding ResB PF05140.14 KXL46117.1 - 1.8 7.2 5.7 3.1 6.4 5.7 1.3 1 0 0 1 1 1 0 ResB-like family Sipho_Gp157 PF05565.11 KXL46117.1 - 1.9 8.5 10.1 8.5 6.4 3.6 2.5 1 1 1 2 2 2 0 Siphovirus Gp157 AAA_13 PF13166.6 KXL46117.1 - 2.3 6.7 5.2 4.6 5.8 5.2 1.4 1 0 0 1 1 1 0 AAA domain Golgin_A5 PF09787.9 KXL46117.1 - 3.1 7.2 18.9 0.017 14.6 7.0 2.5 3 0 0 3 3 3 0 Golgin subfamily A member 5 CLZ PF16526.5 KXL46117.1 - 3.3 8.1 13.5 0.093 13.1 1.7 3.1 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Retrotran_gag_2 PF14223.6 KXL46119.1 - 0.0046 16.6 0.0 0.0054 16.4 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Zn_clus PF00172.18 KXL46120.1 - 3e-06 27.2 10.7 7.9e-06 25.9 10.7 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXL46120.1 - 4.5e-06 25.7 9.3 8.6e-06 24.8 9.3 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KXL46121.1 - 1.1e-39 136.3 30.8 1.6e-39 135.8 30.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXL46121.1 - 9.4e-05 21.9 1.9 9.4e-05 21.9 1.9 2.6 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB Holin_BhlA PF10960.8 KXL46121.1 - 0.0016 18.3 1.3 0.006 16.5 0.0 2.4 3 0 0 3 3 3 1 BhlA holin family Zn_Tnp_IS1595 PF12760.7 KXL46122.1 - 6.3 6.9 10.8 1.9 8.5 2.8 2.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Fungal_trans PF04082.18 KXL46124.1 - 3.4e-13 49.2 0.1 5.1e-13 48.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL46124.1 - 1.2e-08 34.9 10.2 2.4e-08 33.9 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.24 KXL46126.1 - 5.1e-32 111.2 2.0 7e-32 110.7 2.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXL46126.1 - 3.1e-23 81.8 0.0 5.1e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KXL46126.1 - 7e-14 52.4 0.0 4.4e-13 49.9 0.0 2.3 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXL46126.1 - 3.1e-06 27.5 0.3 4.6e-06 26.9 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF1639 PF07797.14 KXL46127.1 - 0.13 12.3 1.4 2.1 8.4 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1639) 4HBT PF03061.22 KXL46128.1 - 2e-08 34.5 0.0 3.3e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily UQ_con PF00179.26 KXL46129.1 - 6.4e-20 71.2 0.0 6.6e-20 71.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KXL46129.1 - 0.0019 18.5 0.0 0.002 18.4 0.0 1.2 1 0 0 1 1 1 1 RWD domain Trs65 PF12735.7 KXL46130.1 - 1.1e-32 113.7 0.0 1.9e-32 112.9 0.0 1.4 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 LIM PF00412.22 KXL46132.1 - 1.2e-25 89.5 33.1 2.2e-09 37.4 4.2 3.7 4 0 0 4 4 4 3 LIM domain DZR PF12773.7 KXL46132.1 - 0.011 15.8 6.0 0.011 15.8 6.0 4.0 3 1 0 3 3 3 0 Double zinc ribbon HLH PF00010.26 KXL46133.1 - 8.1e-14 51.3 0.4 2.2e-13 49.9 0.5 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain GDH_N PF12466.8 KXL46133.1 - 0.038 14.2 0.3 0.27 11.5 0.0 2.3 2 0 0 2 2 2 0 Glutamate dehydrogenase N terminal PIEZO PF15917.5 KXL46133.1 - 0.04 13.4 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 Piezo SUZ PF12752.7 KXL46136.1 - 0.00055 20.6 13.3 0.00055 20.6 13.3 3.3 3 2 0 3 3 3 1 SUZ domain SUZ-C PF12901.7 KXL46136.1 - 0.0037 17.2 2.1 0.011 15.7 2.1 1.8 1 0 0 1 1 1 1 SUZ-C motif vATP-synt_E PF01991.18 KXL46136.1 - 1.8 7.9 8.8 43 3.4 8.6 2.0 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit CDC45 PF02724.14 KXL46136.1 - 8.5 4.5 9.0 12 4.0 9.0 1.2 1 0 0 1 1 1 0 CDC45-like protein HCO3_cotransp PF00955.21 KXL46138.1 - 7e-66 223.1 5.5 2e-36 125.9 4.3 3.0 2 1 1 3 3 3 3 HCO3- transporter family Rhomboid PF01694.22 KXL46140.1 - 6.3e-22 78.2 10.0 1.1e-21 77.4 10.0 1.4 1 0 0 1 1 1 1 Rhomboid family Ntox15 PF15604.6 KXL46140.1 - 0.015 15.4 0.2 0.025 14.7 0.2 1.3 1 0 0 1 1 1 0 Novel toxin 15 WH2 PF02205.20 KXL46142.1 - 1.1e-08 34.6 0.8 2.8e-08 33.3 0.8 1.8 1 0 0 1 1 1 1 WH2 motif CAP_N PF01213.19 KXL46142.1 - 0.00058 19.4 10.5 0.00058 19.4 10.5 8.9 2 2 4 6 6 6 1 Adenylate cyclase associated (CAP) N terminal PKD_channel PF08016.12 KXL46143.1 - 1.4 7.6 13.9 3 6.4 4.8 2.4 1 1 1 2 2 2 0 Polycystin cation channel RNase_PH PF01138.21 KXL46145.1 - 1e-27 97.2 0.0 2.4e-27 96.0 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KXL46145.1 - 0.012 15.6 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 DUF4412 PF14371.6 KXL46145.1 - 0.071 12.9 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4412) Pmp3 PF01679.17 KXL46146.1 - 1.3e-19 70.1 8.1 1.7e-19 69.7 8.1 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator EamA PF00892.20 KXL46147.1 - 0.01 16.0 17.0 0.096 12.9 17.0 2.0 1 1 0 1 1 1 0 EamA-like transporter family ERG4_ERG24 PF01222.17 KXL46147.1 - 0.036 12.8 0.6 0.041 12.6 0.6 1.1 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family DUF2754 PF10953.8 KXL46147.1 - 0.096 12.9 0.3 10 6.5 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2754) TFIIA_gamma_C PF02751.14 KXL46148.1 - 2.1e-24 85.4 1.3 3e-24 84.9 1.3 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 KXL46148.1 - 9.1e-23 80.0 0.1 1.2e-22 79.6 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain ATP-synt_C PF00137.21 KXL46149.1 - 8.8e-25 86.8 33.8 3.1e-15 56.3 10.7 3.0 3 0 0 3 3 3 2 ATP synthase subunit C SLATT_5 PF18160.1 KXL46149.1 - 0.033 13.5 0.7 0.033 13.5 0.7 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 MoCF_biosynth PF00994.24 KXL46150.1 - 3.4e-52 176.0 0.5 6e-27 94.1 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 KXL46150.1 - 2.8e-37 127.9 1.2 4.6e-37 127.2 1.2 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 KXL46150.1 - 2.2e-15 56.6 0.0 5.6e-15 55.3 0.0 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) adh_short_C2 PF13561.6 KXL46151.1 - 2.5e-31 109.1 1.0 3.5e-31 108.6 1.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL46151.1 - 1.8e-29 102.6 0.5 2.3e-29 102.2 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL46151.1 - 2.2e-06 27.7 0.3 3.5e-06 27.0 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL46151.1 - 2e-05 24.2 0.2 0.00014 21.4 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Phi-29_GP16_7 PF06720.11 KXL46151.1 - 0.027 14.3 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 DEAD PF00270.29 KXL46152.1 - 8.5e-47 159.2 0.0 1.6e-46 158.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXL46152.1 - 3.5e-24 85.3 0.0 1.3e-23 83.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KXL46152.1 - 2.4e-19 69.3 0.0 5.4e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KXL46152.1 - 4.8e-05 23.4 0.0 0.00016 21.7 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit FAM110_C PF14160.6 KXL46152.1 - 0.25 12.4 4.3 0.25 12.4 1.2 2.5 2 0 0 2 2 2 0 Centrosome-associated C terminus CMS1 PF14617.6 KXL46152.1 - 0.69 9.2 0.0 0.69 9.2 0.0 4.9 4 1 0 5 5 5 0 U3-containing 90S pre-ribosomal complex subunit DnaJ PF00226.31 KXL46153.1 - 2.3e-15 56.4 1.7 3.9e-15 55.7 0.4 2.1 2 0 0 2 2 2 1 DnaJ domain Cytomega_UL84 PF06284.11 KXL46153.1 - 0.17 10.3 3.6 0.23 9.9 3.6 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein V-SNARE_C PF12352.8 KXL46154.1 - 0.046 14.0 0.2 0.11 12.8 0.2 1.6 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus PRKG1_interact PF15898.5 KXL46154.1 - 0.088 13.7 0.8 0.85 10.6 0.1 2.4 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Gpr1_Fun34_YaaH PF01184.19 KXL46155.1 - 3.6e-22 79.0 17.8 4.5e-22 78.7 17.8 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family GerA PF03323.13 KXL46155.1 - 0.47 8.9 11.0 0.053 12.0 6.4 1.6 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein 4HBT PF03061.22 KXL46156.1 - 1.7e-08 34.7 0.0 2.3e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 KXL46156.1 - 0.00054 19.3 0.5 0.00078 18.8 0.5 1.1 1 0 0 1 1 1 1 Acyl-ACP thioesterase 4HBT_2 PF13279.6 KXL46156.1 - 0.0025 18.3 0.0 0.0032 17.9 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily PAXNEB PF05625.11 KXL46157.1 - 6.3e-93 311.9 0.0 8.5e-93 311.4 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein Caps_synth PF05704.12 KXL46158.1 - 1.1e-12 48.0 0.0 1.9e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 KXL46158.1 - 3e-06 27.8 0.0 6.5e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Glyco_hydro_35 PF01301.19 KXL46159.1 - 4.2e-91 305.8 0.2 7.2e-91 305.1 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 KXL46159.1 - 1e-55 188.4 0.4 2.2e-55 187.3 0.4 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 KXL46159.1 - 5e-52 175.3 6.4 2.6e-28 98.9 0.1 2.6 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 KXL46159.1 - 1.2e-22 79.3 0.2 4.1e-22 77.5 0.2 1.9 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Sin_N PF04801.13 KXL46160.1 - 1.5e-27 96.9 0.0 2.4e-27 96.2 0.0 1.3 1 1 0 1 1 1 1 Sin-like protein conserved region MMS1_N PF10433.9 KXL46161.1 - 1.4e-121 406.6 0.0 1.8e-121 406.2 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KXL46161.1 - 3.5e-66 223.7 0.0 7e-66 222.7 0.0 1.5 1 0 0 1 1 1 1 CPSF A subunit region ICAP-1_inte_bdg PF10480.9 KXL46161.1 - 0.042 13.8 0.1 0.098 12.6 0.0 1.6 2 0 0 2 2 2 0 Beta-1 integrin binding protein HPS3_N PF14761.6 KXL46161.1 - 0.074 12.6 0.3 4.3 6.8 0.0 3.3 3 0 0 3 3 3 0 Hermansky-Pudlak syndrome 3 tify PF06200.14 KXL46161.1 - 0.14 11.5 0.0 2 7.8 0.0 2.7 3 0 0 3 3 3 0 tify domain RRM_1 PF00076.22 KXL46162.1 - 0.00029 20.6 0.0 0.0071 16.1 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) N-SET PF11764.8 KXL46162.1 - 0.025 14.7 0.1 0.025 14.7 0.1 2.3 3 0 0 3 3 3 0 COMPASS (Complex proteins associated with Set1p) component N WD40 PF00400.32 KXL46163.1 - 1.3e-11 44.9 2.3 0.031 15.1 0.1 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL46163.1 - 8.6e-06 26.0 0.0 0.72 10.2 0.0 4.5 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXL46163.1 - 0.00026 20.1 0.1 1.4 7.8 0.0 3.3 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ADH_N PF08240.12 KXL46164.1 - 1.7e-28 98.7 1.1 2.8e-28 98.0 1.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXL46164.1 - 8.6e-10 38.7 0.0 1.5e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXL46164.1 - 1e-08 35.0 0.5 0.0022 17.5 0.0 2.4 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus ATP_bind_1 PF03029.17 KXL46165.1 - 2.9e-60 204.1 0.0 4.3e-60 203.5 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 KXL46165.1 - 0.0013 19.3 0.1 0.0061 17.1 0.0 2.2 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXL46165.1 - 0.014 15.8 0.0 0.039 14.3 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain KTI12 PF08433.10 KXL46165.1 - 0.029 13.8 0.0 0.062 12.7 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 T2SSE PF00437.20 KXL46165.1 - 0.029 13.4 0.1 0.2 10.7 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.6 KXL46165.1 - 0.05 13.4 0.0 0.093 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 KXL46165.1 - 0.079 12.7 2.0 0.86 9.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KXL46165.1 - 0.1 12.1 1.3 3.5 7.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain CFEM PF05730.11 KXL46166.1 - 3.6e-12 46.2 9.3 6e-12 45.5 9.3 1.4 1 0 0 1 1 1 1 CFEM domain DUF4491 PF14898.6 KXL46166.1 - 0.14 12.6 1.4 0.44 11.0 1.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) Peroxidase_2 PF01328.17 KXL46167.1 - 6.3e-46 157.3 0.0 7.9e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Ribosomal_L1 PF00687.21 KXL46170.1 - 3.6e-62 209.7 0.1 4.5e-62 209.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Zn_clus PF00172.18 KXL46171.1 - 8.3e-08 32.2 9.5 8.3e-08 32.2 9.5 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXL46171.1 - 5e-06 25.7 0.5 2.5e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Cwf_Cwc_15 PF04889.12 KXL46172.1 - 0.00054 19.8 16.3 0.00057 19.7 16.3 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein FYDLN_acid PF09538.10 KXL46172.1 - 0.0035 18.0 15.3 0.0043 17.7 15.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (FYDLN_acid) RNA_pol_3_Rpc31 PF11705.8 KXL46172.1 - 0.0059 16.9 20.0 0.0059 16.9 20.0 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Sporozoite_P67 PF05642.11 KXL46172.1 - 0.0067 14.6 6.5 0.0075 14.4 6.5 1.0 1 0 0 1 1 1 1 Sporozoite P67 surface antigen RXT2_N PF08595.11 KXL46172.1 - 0.0085 16.1 9.1 0.0091 16.0 9.1 1.2 1 0 0 1 1 1 1 RXT2-like, N-terminal NOA36 PF06524.12 KXL46172.1 - 0.013 14.9 15.3 0.013 14.9 15.3 1.1 1 0 0 1 1 1 0 NOA36 protein Pox_Ag35 PF03286.14 KXL46172.1 - 0.018 14.9 7.7 0.019 14.7 7.7 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Paf1 PF03985.13 KXL46172.1 - 0.019 14.0 7.6 0.018 14.1 7.6 1.0 1 0 0 1 1 1 0 Paf1 TFB6 PF17110.5 KXL46172.1 - 0.021 14.6 5.8 0.022 14.5 5.8 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Sigma70_ner PF04546.13 KXL46172.1 - 0.037 13.9 11.9 0.037 13.9 11.9 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region SDA1 PF05285.12 KXL46172.1 - 0.05 13.0 12.9 0.048 13.1 12.9 1.1 1 0 0 1 1 1 0 SDA1 RPN2_C PF18004.1 KXL46172.1 - 0.051 13.5 2.9 0.052 13.5 2.9 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Nop14 PF04147.12 KXL46172.1 - 0.056 11.7 15.6 0.054 11.7 15.6 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2722 PF10846.8 KXL46172.1 - 0.069 12.1 7.4 0.07 12.1 7.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) BUD22 PF09073.10 KXL46172.1 - 0.11 11.8 11.5 0.11 11.9 11.5 1.0 1 0 0 1 1 1 0 BUD22 CAF1A PF12253.8 KXL46172.1 - 0.12 12.5 16.2 0.17 12.1 16.2 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A DUF5523 PF17661.1 KXL46172.1 - 0.17 11.6 9.6 0.18 11.4 9.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) V_ATPase_I PF01496.19 KXL46172.1 - 0.21 9.4 0.4 0.22 9.4 0.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2428 PF10350.9 KXL46172.1 - 0.26 10.5 2.3 0.32 10.2 2.3 1.1 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) DUF4820 PF16091.5 KXL46172.1 - 0.29 10.5 4.3 0.3 10.4 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) PPP4R2 PF09184.11 KXL46172.1 - 0.32 10.6 15.3 0.32 10.6 15.3 1.1 1 0 0 1 1 1 0 PPP4R2 Rhabdo_ncap PF00945.18 KXL46172.1 - 0.41 9.5 4.7 0.39 9.5 4.7 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Astro_capsid_p PF12226.8 KXL46172.1 - 0.42 9.7 15.1 0.42 9.7 15.1 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF4746 PF15928.5 KXL46172.1 - 0.65 9.4 9.4 0.65 9.4 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) IFT57 PF10498.9 KXL46172.1 - 0.75 8.7 8.5 0.84 8.5 8.5 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 TRAP_alpha PF03896.16 KXL46172.1 - 0.9 8.7 9.7 0.99 8.5 9.7 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PBP_sp32 PF07222.12 KXL46172.1 - 1 8.8 6.1 1 8.8 6.1 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CDC45 PF02724.14 KXL46172.1 - 1.1 7.5 15.4 1.3 7.3 15.4 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 KXL46172.1 - 1.3 8.0 2.9 1.3 8.0 2.9 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Zip PF02535.22 KXL46172.1 - 1.3 8.1 3.3 1.2 8.3 3.3 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter RRN3 PF05327.11 KXL46172.1 - 1.4 7.4 12.6 1.4 7.4 12.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2076 PF09849.9 KXL46172.1 - 1.8 8.6 7.5 1.9 8.5 7.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DNA_pol_phi PF04931.13 KXL46172.1 - 2.9 5.9 29.4 3.6 5.6 29.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi CobT PF06213.12 KXL46172.1 - 3.1 7.1 18.0 3.7 6.9 18.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Radial_spoke PF04712.12 KXL46172.1 - 3.1 6.6 11.2 3.4 6.5 11.2 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein DUF2457 PF10446.9 KXL46172.1 - 4.8 6.2 28.3 5.8 5.9 28.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) HSP90 PF00183.18 KXL46172.1 - 5.7 5.7 10.4 6.2 5.6 10.4 1.0 1 0 0 1 1 1 0 Hsp90 protein DUF4637 PF15470.6 KXL46172.1 - 7.7 6.2 16.5 12 5.6 16.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Cytomega_UL84 PF06284.11 KXL46172.1 - 8.7 4.7 9.7 9.5 4.5 9.7 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein AvrM-A PF18241.1 KXL46173.1 - 0.034 14.6 0.0 0.038 14.4 0.0 1.1 1 0 0 1 1 1 0 Flax-rust effector AvrM-A BSP_II PF05432.11 KXL46175.1 - 0.0044 16.8 8.9 0.005 16.6 8.9 1.0 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) DUF5520 PF17658.1 KXL46175.1 - 0.0061 15.7 1.8 0.0065 15.6 1.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5520) PEX11 PF05648.14 KXL46175.1 - 0.043 13.3 0.8 0.055 12.9 0.8 1.1 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) FAM176 PF14851.6 KXL46175.1 - 0.054 13.2 3.6 0.064 12.9 3.6 1.1 1 0 0 1 1 1 0 FAM176 family DUF5523 PF17661.1 KXL46175.1 - 0.066 12.9 9.4 0.076 12.7 9.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DFF40 PF09230.10 KXL46175.1 - 0.069 12.8 0.9 0.073 12.7 0.9 1.0 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa TRAP_alpha PF03896.16 KXL46175.1 - 0.12 11.5 2.3 0.14 11.3 2.3 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PI3K_1B_p101 PF10486.9 KXL46175.1 - 0.13 10.0 2.8 0.15 9.8 2.8 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Atrophin-1 PF03154.15 KXL46175.1 - 0.18 10.1 7.3 0.2 9.9 7.3 1.0 1 0 0 1 1 1 0 Atrophin-1 family Usp PF00582.26 KXL46175.1 - 0.19 12.2 2.7 0.23 12.0 2.7 1.1 1 0 0 1 1 1 0 Universal stress protein family Cnd2 PF05786.14 KXL46175.1 - 0.38 9.4 6.4 0.41 9.2 6.4 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 GOLD_2 PF13897.6 KXL46175.1 - 0.51 10.8 2.9 0.62 10.6 2.9 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking CDC45 PF02724.14 KXL46175.1 - 0.55 8.4 5.4 0.62 8.3 5.4 1.0 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 KXL46175.1 - 0.64 8.0 8.5 0.69 7.9 8.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi Cytomega_UL84 PF06284.11 KXL46175.1 - 0.75 8.2 3.5 0.69 8.3 3.5 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DUF4637 PF15470.6 KXL46175.1 - 1.2 8.9 9.1 1.5 8.5 9.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Radial_spoke PF04712.12 KXL46175.1 - 1.6 7.6 10.0 1.8 7.4 10.0 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein NOA36 PF06524.12 KXL46175.1 - 2.8 7.2 7.9 3.4 6.9 7.9 1.1 1 0 0 1 1 1 0 NOA36 protein DUF4618 PF15397.6 KXL46176.1 - 0.0014 18.2 21.0 0.0019 17.7 21.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) DUF1891 PF09004.10 KXL46176.1 - 0.073 12.7 2.0 0.22 11.2 2.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1891) CDC45 PF02724.14 KXL46176.1 - 8.5 4.5 20.6 10 4.3 20.6 1.2 1 0 0 1 1 1 0 CDC45-like protein MDM10 PF12519.8 KXL46176.1 - 9.9 4.9 10.1 12 4.7 10.1 1.4 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 NT-C2 PF10358.9 KXL46177.1 - 2.3e-28 98.8 0.0 3e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Spherulin4 PF12138.8 KXL46180.1 - 4.6e-59 200.0 0.9 5.2e-59 199.8 0.9 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 MFS_1 PF07690.16 KXL46181.1 - 0.00089 18.3 10.8 0.001 18.1 10.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily WD40 PF00400.32 KXL46183.1 - 5.4e-14 52.4 14.9 0.011 16.6 0.3 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat VID27_N PF17748.1 KXL46183.1 - 0.013 15.3 4.0 0.037 13.9 4.1 1.7 2 0 0 2 2 2 0 VID27 N-terminal region MraZ PF02381.18 KXL46183.1 - 0.021 14.8 0.0 2.4 8.2 0.0 2.5 2 0 0 2 2 2 0 MraZ protein, putative antitoxin-like DUF2457 PF10446.9 KXL46183.1 - 0.029 13.5 19.5 0.063 12.4 19.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 KXL46183.1 - 0.087 11.0 16.6 0.14 10.4 16.6 1.2 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.14 KXL46183.1 - 0.25 11.1 9.7 0.54 10.0 9.7 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CENP-B_dimeris PF09026.10 KXL46183.1 - 0.42 11.0 25.5 1.4 9.4 25.5 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 KXL46183.1 - 0.63 8.1 23.1 1 7.4 23.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 KXL46183.1 - 1.1 8.9 7.6 2.9 7.5 7.6 1.7 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 KXL46183.1 - 1.3 8.3 24.7 1.9 7.7 24.7 1.2 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 KXL46183.1 - 1.3 8.7 26.0 2.5 7.8 26.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.13 KXL46183.1 - 1.5 8.6 11.2 2.7 7.9 11.2 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region RXT2_N PF08595.11 KXL46183.1 - 3.4 7.7 15.4 0.65 10.0 11.4 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal RRN3 PF05327.11 KXL46183.1 - 9.5 4.6 10.7 13 4.2 10.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Glyco_hydro_64 PF16483.5 KXL46184.1 - 4.3e-100 335.6 0.1 4.8e-100 335.4 0.1 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase zf-C2H2_12 PF18658.1 KXL46185.1 - 0.0033 17.0 0.4 0.0069 15.9 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger C2H2-type Kin17_mid PF10357.9 KXL46186.1 - 5.4e-52 175.0 0.2 1e-51 174.1 0.2 1.5 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 KXL46186.1 - 0.00022 21.4 2.3 0.00022 21.4 2.3 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXL46186.1 - 0.0003 21.1 3.0 0.0007 19.9 3.0 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KXL46186.1 - 0.004 17.5 4.7 0.006 16.9 0.5 2.3 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Bestrophin PF01062.21 KXL46186.1 - 0.073 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel AMPK1_CBM PF16561.5 KXL46187.1 - 8.4e-27 93.2 0.1 1.5e-26 92.5 0.1 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 KXL46187.1 - 1.8e-23 82.6 1.7 1.8e-23 82.6 1.7 3.1 4 1 0 4 4 4 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM_48 PF02922.18 KXL46187.1 - 0.004 17.5 0.0 0.0079 16.5 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) p450 PF00067.22 KXL46189.1 - 2.3e-14 53.0 0.1 1.8e-09 36.9 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 adh_short PF00106.25 KXL46190.1 - 1.8e-19 69.9 0.4 2.9e-18 66.0 0.4 2.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL46190.1 - 1.3e-11 44.6 0.0 6.8e-11 42.2 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase AAA PF00004.29 KXL46191.1 - 1.3e-16 61.2 0.0 2.4e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 KXL46191.1 - 1.6e-15 57.3 0.0 4.1e-15 56.0 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KXL46191.1 - 7.1e-15 55.2 0.0 2.3e-14 53.5 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KXL46191.1 - 8.7e-08 32.3 0.0 1.5e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 KXL46191.1 - 4.2e-07 30.2 0.0 1.2e-06 28.7 0.0 1.8 2 0 0 2 2 1 1 AAA C-terminal domain AAA_30 PF13604.6 KXL46191.1 - 1.6e-06 28.0 0.0 3.2e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXL46191.1 - 1.5e-05 25.5 0.0 5.2e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.6 KXL46191.1 - 1.6e-05 24.8 0.6 0.0021 17.9 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 KXL46191.1 - 2.7e-05 24.5 0.1 0.00012 22.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXL46191.1 - 2.9e-05 24.1 0.1 0.00015 21.8 0.1 2.3 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) DNA_pol3_delta PF06144.13 KXL46191.1 - 4.9e-05 23.2 0.1 8.1e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit RuvB_N PF05496.12 KXL46191.1 - 6.9e-05 22.6 0.0 0.0002 21.2 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 KXL46191.1 - 7e-05 22.9 0.0 0.029 14.4 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KXL46191.1 - 0.00026 20.5 0.0 0.045 13.2 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_28 PF13521.6 KXL46191.1 - 0.00078 19.7 0.0 0.0017 18.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KXL46191.1 - 0.00079 19.2 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KXL46191.1 - 0.0011 18.3 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.11 KXL46191.1 - 0.0019 18.0 0.0 0.0068 16.3 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 KXL46191.1 - 0.0022 17.2 0.0 0.0036 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KXL46191.1 - 0.0024 18.4 0.0 0.0046 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KXL46191.1 - 0.0024 17.3 0.0 0.022 14.1 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KXL46191.1 - 0.0035 17.1 0.0 0.0061 16.3 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain DEAD PF00270.29 KXL46191.1 - 0.0056 16.5 0.2 0.031 14.1 0.1 2.0 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.6 KXL46191.1 - 0.0091 16.3 0.1 0.036 14.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KXL46191.1 - 0.0098 15.6 0.0 0.23 11.2 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.6 KXL46191.1 - 0.033 13.8 0.0 0.13 11.8 0.0 1.8 1 1 1 2 2 2 0 AAA domain TniB PF05621.11 KXL46191.1 - 0.045 13.1 0.0 0.3 10.5 0.0 2.2 1 1 0 1 1 1 0 Bacterial TniB protein RNA_helicase PF00910.22 KXL46191.1 - 0.046 14.1 0.0 0.083 13.3 0.0 1.5 1 1 0 1 1 1 0 RNA helicase TIP49 PF06068.13 KXL46191.1 - 0.056 12.6 0.0 0.098 11.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_7 PF12775.7 KXL46191.1 - 0.065 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region P21-Arc PF04062.14 KXL46192.1 - 2.9e-74 248.9 0.0 3.3e-74 248.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit GRDP-like PF07173.12 KXL46193.1 - 5.5e-18 66.0 1.9 4e-14 53.5 0.1 3.4 3 0 0 3 3 3 2 Glycine-rich domain-containing protein-like zf-U1 PF06220.12 KXL46193.1 - 0.12 12.2 1.2 0.4 10.5 1.2 1.9 1 0 0 1 1 1 0 U1 zinc finger DM PF00751.18 KXL46193.1 - 1.4 8.9 5.3 0.19 11.7 0.9 1.8 2 0 0 2 2 2 0 DM DNA binding domain GARS_A PF01071.19 KXL46194.1 - 9.2e-86 286.6 0.0 1.2e-85 286.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 KXL46194.1 - 8.1e-32 109.9 0.0 1.4e-31 109.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 KXL46194.1 - 1.8e-28 98.6 0.2 4.2e-28 97.5 0.2 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp PF02222.22 KXL46194.1 - 4.8e-06 26.3 0.0 7.8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KXL46194.1 - 0.0001 22.4 0.0 0.00027 21.0 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 KXL46194.1 - 0.013 15.0 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 KXL46194.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_ST PF14397.6 KXL46194.1 - 0.061 12.6 0.1 0.24 10.6 0.0 1.9 3 0 0 3 3 3 0 Sugar-transfer associated ATP-grasp ATP-grasp_2 PF08442.10 KXL46194.1 - 0.16 11.5 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain MINDY_DUB PF04424.13 KXL46195.1 - 8.6e-26 90.3 0.0 1.6e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 MINDY deubiquitinase CCDC50_N PF15295.6 KXL46195.1 - 0.22 11.7 6.3 0.43 10.7 6.3 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus Ligase_CoA PF00549.19 KXL46196.1 - 7.1e-24 84.4 0.2 9e-24 84.0 0.2 1.1 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KXL46196.1 - 1.4e-10 41.1 0.1 1.9e-10 40.7 0.1 1.3 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain PIG-X PF08320.12 KXL46197.1 - 4.2e-65 219.6 0.0 5.6e-65 219.2 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 DUF410 PF04190.13 KXL46198.1 - 1.1e-90 303.9 0.0 1.7e-90 303.3 0.0 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF410) MoaE PF02391.17 KXL46199.1 - 0.011 16.0 0.0 0.021 15.1 0.0 1.4 1 1 0 1 1 1 0 MoaE protein MMR_HSR1 PF01926.23 KXL46200.1 - 1.1e-16 60.9 0.2 4.5e-15 55.7 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXL46200.1 - 1e-07 31.6 0.3 1e-05 25.1 0.1 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KXL46200.1 - 3e-05 24.0 0.1 0.0019 18.1 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 KXL46200.1 - 0.0078 15.6 0.1 0.014 14.7 0.1 1.4 1 0 0 1 1 1 1 AIG1 family SDA1 PF05285.12 KXL46200.1 - 0.038 13.4 12.7 0.073 12.5 12.7 1.4 1 0 0 1 1 1 0 SDA1 Dynamin_N PF00350.23 KXL46200.1 - 0.076 13.1 2.7 0.11 12.5 0.0 2.6 3 0 0 3 3 3 0 Dynamin family LTV PF04180.14 KXL46201.1 - 1.1e-116 390.7 22.4 1.3e-116 390.5 22.4 1.0 1 0 0 1 1 1 1 Low temperature viability protein UreF PF01730.16 KXL46202.1 - 7.8e-26 91.2 0.8 1.2e-25 90.6 0.8 1.2 1 0 0 1 1 1 1 UreF CH PF00307.31 KXL46203.1 - 3.1e-48 162.5 0.3 2.1e-22 79.4 0.4 3.1 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 KXL46203.1 - 6.9e-25 86.9 0.0 2e-24 85.4 0.0 1.9 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 KXL46203.1 - 1.1e-10 41.1 1.4 2.9e-07 30.2 0.1 3.2 3 0 0 3 3 3 2 CAMSAP CH domain CH_2 PF06294.11 KXL46203.1 - 0.00087 19.4 0.1 0.054 13.6 0.1 3.0 2 0 0 2 2 2 1 CH-like domain in sperm protein zf-RRPl_C4 PF17026.5 KXL46203.1 - 0.0024 18.0 0.3 0.012 15.7 0.1 2.1 2 0 0 2 2 2 1 Putative ribonucleoprotein zinc-finger pf C4 type EF-hand_8 PF13833.6 KXL46203.1 - 0.0043 16.9 0.3 0.084 12.7 0.0 2.7 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KXL46203.1 - 0.0097 15.8 1.8 0.037 13.9 0.1 2.9 3 0 0 3 3 2 1 EF-hand domain EF-hand_1 PF00036.32 KXL46203.1 - 0.012 15.1 0.1 0.6 9.8 0.0 2.8 2 0 0 2 2 2 0 EF hand Spectrin PF00435.21 KXL46203.1 - 0.04 14.4 8.4 1.2 9.6 0.1 3.0 3 0 0 3 3 3 0 Spectrin repeat EF-hand_7 PF13499.6 KXL46203.1 - 0.061 13.8 3.9 0.5 10.9 0.4 3.3 3 0 0 3 3 3 0 EF-hand domain pair DUF2884 PF11101.8 KXL46203.1 - 0.12 11.9 0.1 0.12 11.9 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2884) FliG_N PF14842.6 KXL46203.1 - 0.55 10.8 2.8 1.6 9.3 0.2 2.8 3 0 0 3 3 3 0 FliG N-terminal domain DUF4508 PF14969.6 KXL46203.1 - 0.75 10.1 5.2 2.7 8.3 0.5 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4508) PBD PF00786.28 KXL46204.1 - 0.052 13.9 0.3 0.12 12.8 0.3 1.6 1 0 0 1 1 1 0 P21-Rho-binding domain COG5 PF10392.9 KXL46205.1 - 1.3e-25 90.1 0.1 3.6e-25 88.7 0.1 1.7 1 0 0 1 1 1 1 Golgi transport complex subunit 5 GFA PF04828.14 KXL46206.1 - 9.2e-22 77.2 0.1 1.2e-21 76.8 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.7 KXL46206.1 - 0.011 15.8 5.1 0.053 13.5 2.5 2.2 1 1 1 2 2 2 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 KXL46206.1 - 0.012 15.3 4.7 0.063 13.0 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 KXL46206.1 - 0.023 14.7 3.5 1.9 8.5 0.3 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Ogr_Delta PF04606.12 KXL46206.1 - 0.038 14.0 4.4 0.36 10.8 0.1 2.6 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Nudix_N_2 PF14803.6 KXL46206.1 - 0.044 13.7 0.2 0.044 13.7 0.2 3.2 3 0 0 3 3 3 0 Nudix N-terminal zf-NADH-PPase PF09297.11 KXL46206.1 - 0.048 13.3 0.6 0.048 13.3 0.6 3.2 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain zf-ISL3 PF14690.6 KXL46206.1 - 0.053 14.2 1.4 2.3 8.9 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DNA_ligase_ZBD PF03119.16 KXL46206.1 - 0.18 11.8 5.1 0.64 10.1 0.2 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Zn-ribbon_8 PF09723.10 KXL46206.1 - 0.19 11.8 5.7 0.83 9.8 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain DiS_P_DiS PF06750.13 KXL46206.1 - 0.26 11.4 1.9 1.3 9.2 0.0 2.1 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain DUF35_N PF12172.8 KXL46206.1 - 0.48 10.3 6.7 0.57 10.1 0.7 2.6 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) NOB1_Zn_bind PF08772.11 KXL46206.1 - 0.84 9.8 5.8 6.5 7.0 5.8 2.1 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf-ribbon_3 PF13248.6 KXL46206.1 - 1.2 8.7 10.7 0.27 10.7 0.5 2.7 3 0 0 3 3 3 0 zinc-ribbon domain Zn_ribbon_SprT PF17283.2 KXL46206.1 - 3.4 7.7 9.8 12 5.9 0.3 3.0 2 1 0 2 2 2 0 SprT-like zinc ribbon domain Lactamase_B_3 PF13483.6 KXL46207.1 - 1.7e-06 28.0 0.0 4.8e-06 26.5 0.0 1.7 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 KXL46207.1 - 0.0018 17.9 0.3 0.0027 17.2 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Fungal_trans PF04082.18 KXL46209.1 - 1.7e-16 60.1 0.7 2.8e-16 59.4 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL46209.1 - 2e-05 24.6 12.1 2e-05 24.6 12.1 2.4 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KXL46209.1 - 0.00019 21.7 2.8 0.00019 21.7 2.8 3.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXL46209.1 - 0.0025 18.5 2.4 0.0025 18.5 2.4 4.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KXL46209.1 - 0.022 14.5 15.3 0.092 12.5 2.4 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 KXL46209.1 - 0.022 15.2 4.3 0.022 15.2 4.3 4.1 4 1 0 4 4 4 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KXL46209.1 - 0.029 14.7 10.0 0.54 10.6 0.2 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 KXL46209.1 - 0.18 11.5 2.9 0.58 9.8 0.4 2.6 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 KXL46209.1 - 4.6 7.8 8.6 6.2 7.4 0.3 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type p450 PF00067.22 KXL46210.1 - 4.2e-73 246.7 0.0 4.7e-73 246.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PRMT5_TIM PF17285.2 KXL46211.1 - 1.3e-67 227.7 0.0 1.7e-67 227.3 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 KXL46211.1 - 7.8e-65 217.9 0.0 1.3e-64 217.2 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 KXL46211.1 - 3.4e-56 189.9 0.0 6.1e-56 189.1 0.0 1.5 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Tfb4 PF03850.14 KXL46212.1 - 1.9e-99 332.7 0.0 2.3e-99 332.4 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 zf-RING_5 PF14634.6 KXL46213.1 - 2.2e-08 33.9 6.0 3.8e-08 33.2 6.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KXL46213.1 - 0.00018 21.8 3.6 0.00034 20.9 3.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KXL46213.1 - 0.00053 19.8 6.2 0.0011 18.8 6.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXL46213.1 - 0.0022 17.8 5.5 0.0042 16.9 5.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KXL46213.1 - 0.0023 17.7 5.7 0.0045 16.8 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF641 PF04859.12 KXL46213.1 - 0.0039 17.5 0.8 0.012 15.9 0.1 2.1 1 1 1 2 2 2 1 Plant protein of unknown function (DUF641) zf-C3HC4_2 PF13923.6 KXL46213.1 - 0.0064 16.3 4.4 0.044 13.6 4.7 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-NADH-PPase PF09297.11 KXL46213.1 - 0.018 14.7 0.1 0.046 13.4 0.1 1.7 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain zf-RING_UBOX PF13445.6 KXL46213.1 - 0.019 15.0 3.8 0.089 12.8 2.3 2.4 1 1 1 2 2 2 0 RING-type zinc-finger Cnn_1N PF07989.11 KXL46213.1 - 0.07 13.3 2.5 0.11 12.6 2.5 1.4 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Mito_carr PF00153.27 KXL46213.1 - 0.082 12.8 0.1 0.25 11.3 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial carrier protein DZR PF12773.7 KXL46213.1 - 0.09 12.8 5.6 0.97 9.5 5.0 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_6 PF14835.6 KXL46213.1 - 0.27 11.1 5.5 0.51 10.3 5.5 1.5 1 1 0 1 1 1 0 zf-RING of BARD1-type protein IBR PF01485.21 KXL46213.1 - 0.3 11.4 5.1 2.9 8.2 2.9 2.4 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-C3HC4_4 PF15227.6 KXL46213.1 - 0.5 10.6 5.2 1 9.6 4.8 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DENN PF02141.21 KXL46214.1 - 6.5e-40 137.1 0.1 1.1e-39 136.3 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KXL46214.1 - 5e-05 24.0 0.8 0.0001 23.0 0.0 2.0 2 0 0 2 2 2 1 uDENN domain Elongin_A PF06881.11 KXL46214.1 - 0.019 15.5 6.0 0.077 13.5 6.0 2.0 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A MCC-bdg_PDZ PF10506.9 KXL46214.1 - 0.23 11.5 5.1 0.37 10.8 2.4 2.6 1 1 1 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Seryl_tRNA_N PF02403.22 KXL46214.1 - 3.2 8.0 12.1 0.71 10.1 7.3 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain zf-HIT PF04438.16 KXL46216.1 - 4.8e-06 26.3 9.2 8.2e-06 25.6 9.2 1.4 1 0 0 1 1 1 1 HIT zinc finger DDE_Tnp_1_6 PF13751.6 KXL46216.1 - 0.15 12.3 4.8 0.3 11.3 4.8 1.4 1 0 0 1 1 1 0 Transposase DDE domain Kinesin PF00225.23 KXL46217.1 - 1e-92 310.6 1.0 8.5e-92 307.6 0.0 2.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KXL46217.1 - 3.5e-22 79.0 0.0 2.1e-18 66.7 0.0 3.5 3 0 0 3 3 3 2 Microtubule binding TPR_MLP1_2 PF07926.12 KXL46217.1 - 0.0011 19.0 3.7 0.0011 19.0 3.7 11.0 8 2 2 10 10 10 2 TPR/MLP1/MLP2-like protein ERM PF00769.19 KXL46217.1 - 0.0025 17.7 25.5 0.0025 17.7 25.5 9.3 3 2 6 9 9 9 1 Ezrin/radixin/moesin family Metallophos PF00149.28 KXL46219.1 - 6.1e-34 118.3 0.0 2.1e-29 103.5 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 KXL46219.1 - 0.009 15.7 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain LRR_4 PF12799.7 KXL46221.1 - 3.1e-23 81.4 36.2 1.2e-05 25.5 0.7 8.6 4 2 4 10 10 10 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXL46221.1 - 9.1e-19 67.0 26.9 3.1e-06 26.8 1.8 7.1 5 2 1 7 7 7 5 Leucine rich repeat LRR_9 PF14580.6 KXL46221.1 - 4.5e-09 36.1 14.4 0.053 13.0 0.6 4.3 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 KXL46221.1 - 0.00011 22.3 24.0 5.2 8.0 0.4 9.8 8 2 0 8 8 8 2 Leucine Rich Repeat LRR_6 PF13516.6 KXL46221.1 - 0.00081 19.2 15.3 3.5 7.9 0.0 7.8 8 0 0 8 8 8 2 Leucine Rich repeat DUF3557 PF12078.8 KXL46221.1 - 2.1 8.3 3.8 0.77 9.7 0.3 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3557) Skp1_POZ PF03931.15 KXL46222.1 - 1.4e-08 34.8 0.0 1.9e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 KXL46222.1 - 0.024 14.9 0.2 0.039 14.2 0.2 1.3 1 1 0 1 1 1 0 BTB/POZ domain bZIP_1 PF00170.21 KXL46223.1 - 0.68 10.1 11.8 0.14 12.3 8.0 1.9 2 0 0 2 2 2 0 bZIP transcription factor DASH_Dad1 PF08649.10 KXL46226.1 - 8.4e-25 86.7 1.9 1e-24 86.5 1.9 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 KXL46226.1 - 0.028 14.4 0.5 0.038 13.9 0.5 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad4 Pex2_Pex12 PF04757.14 KXL46227.1 - 7.3e-49 166.4 1.7 9.3e-49 166.0 1.7 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 KXL46227.1 - 1.5e-05 25.1 0.8 2.4e-05 24.4 0.8 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KXL46227.1 - 0.00078 19.2 0.6 0.0013 18.5 0.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXL46227.1 - 0.0012 18.7 0.3 0.0019 18.0 0.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXL46227.1 - 0.0021 18.0 0.6 0.0039 17.2 0.6 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KXL46227.1 - 0.0063 16.8 0.3 0.01 16.1 0.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KXL46227.1 - 0.013 15.3 0.1 0.019 14.8 0.1 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Peptidase_M1 PF01433.20 KXL46228.1 - 5.2e-72 242.0 0.9 1.1e-71 240.9 0.4 1.8 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 KXL46228.1 - 5.2e-69 233.2 2.3 8.7e-69 232.5 2.3 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KXL46228.1 - 1.9e-40 139.1 0.3 3.5e-40 138.2 0.3 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain RE_MjaI PF09568.10 KXL46228.1 - 0.095 12.5 0.0 7.4 6.4 0.0 2.5 2 0 0 2 2 2 0 MjaI restriction endonuclease IBR PF01485.21 KXL46230.1 - 0.0017 18.5 8.1 0.0017 18.5 8.1 3.6 2 1 2 4 4 4 2 IBR domain, a half RING-finger domain zf-H2C2_2 PF13465.6 KXL46230.1 - 1.1 9.8 7.6 17 6.0 0.1 4.3 2 1 0 2 2 2 0 Zinc-finger double domain DUF3328 PF11807.8 KXL46231.1 - 5.9e-35 121.0 0.0 6.9e-35 120.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) 14-3-3 PF00244.20 KXL46233.1 - 1.3e-106 355.1 6.3 1.5e-106 354.9 6.3 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.6 KXL46233.1 - 9.2e-05 22.7 1.6 0.01 16.1 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat Phage_min_cap2 PF06152.11 KXL46233.1 - 0.014 14.3 0.9 0.021 13.7 0.9 1.3 1 0 0 1 1 1 0 Phage minor capsid protein 2 TerB PF05099.13 KXL46233.1 - 0.016 15.1 0.2 0.056 13.4 0.2 1.9 1 0 0 1 1 1 0 Tellurite resistance protein TerB Nsp1_C PF05064.13 KXL46235.1 - 1.3e-30 105.6 0.1 3.2e-30 104.3 0.0 1.6 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 KXL46235.1 - 1.4e-05 25.9 55.1 0.00077 20.3 22.3 6.2 1 1 6 7 7 7 3 Nucleoporin FG repeat region Nup54 PF13874.6 KXL46235.1 - 0.076 13.1 1.0 3.4 7.8 0.1 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 NAD_binding_1 PF00175.21 KXL46236.1 - 8.6e-34 116.5 0.0 1.5e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KXL46236.1 - 4.6e-25 87.8 0.0 1.2e-24 86.5 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KXL46236.1 - 6e-08 33.0 0.0 0.00022 21.4 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KXL46236.1 - 0.066 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Glyco_hydro_45 PF02015.16 KXL46237.1 - 3e-73 246.2 18.4 4.6e-73 245.6 18.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 SOG2 PF10428.9 KXL46237.1 - 0.038 13.2 6.4 0.048 12.9 6.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein ABM PF03992.16 KXL46238.1 - 5e-06 26.5 0.1 6.9e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Lge1 PF11488.8 KXL46238.1 - 0.014 15.5 0.2 0.034 14.3 0.0 1.7 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 DUF4288 PF14119.6 KXL46238.1 - 0.036 14.5 0.2 0.76 10.2 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4288) L27_2 PF09045.10 KXL46238.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 L27_2 MFS_1 PF07690.16 KXL46239.1 - 5.9e-36 124.1 31.6 5.9e-36 124.1 31.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL46239.1 - 1e-11 44.4 8.7 1e-11 44.4 8.7 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KXL46239.1 - 9.3e-06 24.3 2.4 1.6e-05 23.5 2.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1129 PF06570.11 KXL46239.1 - 0.083 12.4 0.6 0.23 10.9 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) PNP_UDP_1 PF01048.20 KXL46243.1 - 0.0009 18.6 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily Multi-haem_cyto PF13447.6 KXL46243.1 - 0.043 13.1 0.0 0.35 10.1 0.1 1.9 2 0 0 2 2 2 0 Seven times multi-haem cytochrome CxxCH MIP PF00230.20 KXL46246.1 - 4.5e-42 144.3 4.4 6.1e-42 143.9 4.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein SPW PF03779.14 KXL46246.1 - 0.054 13.1 0.2 0.17 11.5 0.2 1.9 1 0 0 1 1 1 0 SPW repeat Bax1-I PF01027.20 KXL46246.1 - 7.8 6.3 9.4 21 4.9 8.4 2.0 1 1 1 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 PPP4R2 PF09184.11 KXL46248.1 - 2.2e-10 40.6 0.3 1.1e-09 38.3 0.0 2.0 1 1 1 2 2 2 1 PPP4R2 Fungal_trans PF04082.18 KXL46251.1 - 3.5e-15 55.8 0.9 6.3e-15 54.9 0.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL46251.1 - 1.9e-07 31.1 8.7 3.5e-07 30.2 8.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SURF4 PF02077.15 KXL46252.1 - 5.7e-95 317.9 5.0 6.4e-95 317.8 5.0 1.0 1 0 0 1 1 1 1 SURF4 family DUF3325 PF11804.8 KXL46252.1 - 0.032 14.4 2.7 0.032 14.4 2.7 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF3325) HR_lesion PF05514.11 KXL46252.1 - 9.3 6.4 13.3 0.13 12.4 2.1 2.7 4 0 0 4 4 4 0 HR-like lesion-inducing DDE_Tnp_Tn3 PF01526.17 KXL46253.1 - 0.094 11.5 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Tn3 transposase DDE domain Colicin_E5 PF12106.8 KXL46255.1 - 0.0016 18.7 0.7 0.0062 16.8 0.7 2.0 1 0 0 1 1 1 1 Colicin E5 ribonuclease domain POTRA_TamA_1 PF17243.2 KXL46255.1 - 0.009 16.1 1.0 0.009 16.1 1.0 2.9 2 1 1 3 3 3 1 POTRA domain TamA domain 1 Borrelia_P83 PF05262.11 KXL46255.1 - 0.31 9.5 32.5 0.48 8.9 32.5 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Ndc1_Nup PF09531.10 KXL46255.1 - 9.7 4.7 5.9 12 4.4 5.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup V-ATPase_C PF03223.15 KXL46256.1 - 1.4e-122 409.7 0.0 1.6e-122 409.5 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C GLE1 PF07817.13 KXL46256.1 - 0.064 12.5 0.8 0.11 11.6 0.8 1.4 1 0 0 1 1 1 0 GLE1-like protein APG6_N PF17675.1 KXL46256.1 - 4.8 7.7 7.6 23 5.5 0.3 2.9 2 1 0 2 2 2 0 Apg6 coiled-coil region GCV_T PF01571.21 KXL46257.1 - 5e-76 255.5 0.0 6.5e-76 255.1 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KXL46257.1 - 8.7e-24 83.3 0.3 1.5e-23 82.5 0.3 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DUF3659 PF12396.8 KXL46257.1 - 0.0044 16.9 0.2 0.014 15.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3659) APS_kinase PF01583.20 KXL46259.1 - 2e-71 239.0 0.0 2.5e-71 238.7 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 KXL46259.1 - 3.3e-05 24.1 0.0 4.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KXL46259.1 - 0.00025 20.6 0.0 0.00029 20.4 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 KXL46259.1 - 0.00063 20.3 0.0 0.001 19.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KXL46259.1 - 0.029 14.1 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KXL46259.1 - 0.032 14.6 0.1 0.05 14.0 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain 6PF2K PF01591.18 KXL46259.1 - 0.052 12.8 0.0 0.066 12.5 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase G-alpha PF00503.20 KXL46259.1 - 0.1 11.7 0.1 0.19 10.9 0.1 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Rad60-SLD PF11976.8 KXL46260.1 - 0.01 15.6 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like BLOC1_2 PF10046.9 KXL46260.1 - 0.075 13.3 1.6 0.11 12.9 0.2 1.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Apq12 PF12716.7 KXL46261.1 - 2.8e-16 59.2 12.0 6e-16 58.1 12.0 1.6 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis PAS_9 PF13426.7 KXL46262.1 - 2.8e-16 59.6 0.0 3.7e-15 56.0 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 KXL46262.1 - 4.4e-06 26.7 0.0 1.1e-05 25.3 0.0 1.7 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 KXL46262.1 - 0.0038 17.5 0.4 0.027 14.7 0.0 2.7 3 1 1 4 4 4 1 PAS fold 7TMR-HDED PF07697.11 KXL46262.1 - 0.014 15.5 0.5 0.028 14.6 0.5 1.5 1 0 0 1 1 1 0 7TM-HD extracellular Acetyltransf_1 PF00583.25 KXL46263.1 - 4.1e-06 27.0 0.0 6.8e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXL46263.1 - 5e-06 26.9 0.0 8.8e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXL46263.1 - 3e-05 24.0 0.0 6.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXL46263.1 - 0.018 15.0 0.0 0.047 13.6 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 KXL46263.1 - 0.097 12.7 0.0 0.3 11.2 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain RNA_lig_T4_1 PF09511.10 KXL46264.1 - 3.4e-87 291.9 0.1 5e-87 291.4 0.1 1.3 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.11 KXL46264.1 - 2.2e-83 279.6 0.0 3.2e-83 279.1 0.0 1.3 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.11 KXL46264.1 - 3.8e-52 176.8 0.0 7.7e-52 175.8 0.0 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_18 PF13238.6 KXL46264.1 - 0.0023 18.5 0.2 0.08 13.5 0.1 3.1 2 1 0 2 2 2 1 AAA domain Cauli_VI PF01693.16 KXL46264.1 - 0.057 13.7 0.8 0.11 12.8 0.1 1.9 2 0 0 2 2 2 0 Caulimovirus viroplasmin ABC_tran PF00005.27 KXL46264.1 - 0.11 13.0 0.0 0.51 10.9 0.0 2.0 2 0 0 2 2 2 0 ABC transporter SIR2 PF02146.17 KXL46265.1 - 1e-58 198.2 0.0 1.4e-58 197.8 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 KXL46265.1 - 0.00046 20.0 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 KXL46265.1 - 0.00079 19.2 0.0 0.09 12.5 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Pkinase PF00069.25 KXL46266.1 - 1.1e-56 192.1 0.0 1.5e-56 191.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL46266.1 - 4.3e-32 111.4 0.0 4.2e-31 108.2 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXL46266.1 - 0.025 13.5 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 KXL46266.1 - 0.04 12.9 0.0 0.057 12.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Plasmodium_Vir PF05795.11 KXL46267.1 - 2.7 7.3 7.6 5 6.4 7.6 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein 14-3-3 PF00244.20 KXL46268.1 - 2.5e-11 43.5 0.0 3.8e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 14-3-3 protein MFS_1 PF07690.16 KXL46271.1 - 1.3e-40 139.5 40.2 1.3e-40 139.5 40.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXL46271.1 - 2.3e-10 39.6 19.9 3.8e-10 38.8 19.9 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1682 PF07946.14 KXL46272.1 - 3e-110 368.4 1.1 3.5e-110 368.2 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Cytochrom_NNT PF03264.14 KXL46272.1 - 9.2 5.9 6.1 15 5.2 6.1 1.3 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region DAO PF01266.24 KXL46273.1 - 1.8e-41 142.9 0.1 2.3e-41 142.6 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXL46273.1 - 0.0051 16.8 0.1 1.6 8.7 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 KXL46273.1 - 0.04 13.0 0.0 0.15 11.2 0.0 1.8 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXL46273.1 - 0.046 14.0 0.0 0.16 12.2 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain WD40 PF00400.32 KXL46274.1 - 3.9e-15 56.0 8.2 0.041 14.8 0.2 7.5 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL46274.1 - 1.1e-06 28.9 0.0 2.4 8.5 0.0 4.7 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Glyco_hydro_30C PF17189.4 KXL46274.1 - 0.068 13.4 0.0 0.29 11.4 0.0 2.1 1 1 0 1 1 1 0 Glycosyl hydrolase family 30 beta sandwich domain WD40_like PF17005.5 KXL46274.1 - 0.094 12.0 0.0 5.8 6.1 0.0 2.8 3 0 0 3 3 3 0 WD40-like domain DUF4267 PF14087.6 KXL46275.1 - 1.5e-20 73.4 0.3 2e-20 72.9 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Lyase_1 PF00206.20 KXL46276.1 - 9.4e-25 87.7 0.0 1.9e-24 86.6 0.0 1.4 2 0 0 2 2 2 1 Lyase ADSL_C PF10397.9 KXL46276.1 - 1.4e-17 64.0 0.0 4.6e-17 62.3 0.0 2.0 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus AMP-binding PF00501.28 KXL46277.1 - 2.2e-94 316.5 0.0 2.6e-94 316.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXL46277.1 - 4.5e-19 69.2 0.4 4.5e-19 69.2 0.4 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.25 KXL46278.1 - 1e-64 218.5 0.0 1.2e-64 218.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL46278.1 - 3.1e-34 118.5 0.0 3.9e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXL46278.1 - 0.00047 19.2 0.0 0.00059 18.9 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KXL46278.1 - 0.00054 19.9 0.0 0.019 14.9 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXL46278.1 - 0.0037 16.1 0.0 0.0058 15.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXL46278.1 - 0.029 13.7 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.11 KXL46278.1 - 0.056 12.5 0.0 0.092 11.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Sod_Cu PF00080.20 KXL46279.1 - 9.9e-46 155.4 5.8 1.1e-45 155.2 5.8 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) TAL_FSA PF00923.19 KXL46280.1 - 8.6e-98 327.2 0.4 9.8e-98 327.0 0.4 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase C5-epim_C PF06662.13 KXL46280.1 - 0.014 14.9 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus YEATS PF03366.16 KXL46281.1 - 4.9e-28 96.9 0.0 7.2e-28 96.4 0.0 1.2 1 0 0 1 1 1 1 YEATS family SYF2 PF08231.12 KXL46282.1 - 2.2e-52 177.7 14.3 2.2e-52 177.7 14.3 2.1 2 1 0 2 2 2 1 SYF2 splicing factor SMC_N PF02463.19 KXL46283.1 - 2.4e-72 242.9 0.0 3.9e-72 242.2 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KXL46283.1 - 9.2e-30 103.4 1.5 1.1e-28 99.9 0.1 3.1 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KXL46283.1 - 5.7e-21 75.9 10.1 5.7e-21 75.9 10.1 7.6 1 1 3 4 4 4 1 AAA domain AAA_21 PF13304.6 KXL46283.1 - 7.5e-18 65.4 7.9 1.1e-10 41.8 0.0 3.1 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KXL46283.1 - 8.4e-12 45.5 57.5 3.4e-08 33.6 27.0 4.9 2 2 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.6 KXL46283.1 - 0.022 15.0 0.1 0.18 12.1 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KXL46283.1 - 0.023 14.4 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NPV_P10 PF05531.12 KXL46283.1 - 0.24 11.9 41.6 0.097 13.2 0.4 8.6 6 2 2 9 9 9 0 Nucleopolyhedrovirus P10 protein DUF87 PF01935.17 KXL46283.1 - 2 8.4 0.0 2 8.4 0.0 7.2 3 2 1 4 4 4 0 Helicase HerA, central domain APG6_N PF17675.1 KXL46283.1 - 8.8 6.9 139.9 0.065 13.8 14.0 8.6 3 2 5 8 8 8 0 Apg6 coiled-coil region TMEM208_SND2 PF05620.11 KXL46285.1 - 2.3e-51 173.9 0.1 2.6e-51 173.8 0.1 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 TPR_2 PF07719.17 KXL46286.1 - 5.8e-38 126.0 11.0 6.6e-07 29.0 0.1 9.9 10 0 0 10 10 9 8 Tetratricopeptide repeat TPR_1 PF00515.28 KXL46286.1 - 3.7e-35 118.3 6.7 5.8e-07 29.1 0.1 9.1 9 0 0 9 9 9 7 Tetratricopeptide repeat ANAPC3 PF12895.7 KXL46286.1 - 3.7e-26 91.1 9.4 1.5e-17 63.6 0.3 4.4 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KXL46286.1 - 1.3e-21 75.0 11.1 0.0018 18.4 0.0 9.2 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 KXL46286.1 - 9.5e-21 74.1 9.7 7.4e-08 32.8 0.1 7.3 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 KXL46286.1 - 4.3e-19 67.9 1.8 0.0001 21.9 0.0 8.4 6 2 3 9 9 9 3 TPR repeat TPR_14 PF13428.6 KXL46286.1 - 3e-18 64.9 12.4 8.9e-05 23.0 0.0 8.6 6 2 4 10 10 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 KXL46286.1 - 4.6e-17 62.4 17.9 2.8e-07 31.0 0.1 6.6 5 2 2 7 7 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 KXL46286.1 - 3.3e-15 55.3 8.8 0.015 15.6 0.0 8.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXL46286.1 - 1e-13 51.4 16.3 0.00049 20.3 0.2 8.1 5 1 4 9 9 9 5 Tetratricopeptide repeat TPR_7 PF13176.6 KXL46286.1 - 2.2e-11 43.0 9.1 0.16 12.1 0.0 8.0 9 1 0 9 9 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 KXL46286.1 - 2.9e-08 33.8 13.6 0.079 13.6 0.1 7.8 10 0 0 10 10 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 KXL46286.1 - 2.2e-07 30.9 8.2 0.051 13.7 0.2 5.3 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_15 PF13429.6 KXL46286.1 - 0.00048 19.4 4.2 0.32 10.2 0.0 4.8 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KXL46286.1 - 0.0016 17.9 3.5 0.45 9.8 0.1 4.0 3 1 0 4 4 4 1 MalT-like TPR region ChAPs PF09295.10 KXL46286.1 - 0.017 14.1 0.1 4.4 6.2 0.0 2.6 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) SRP_TPR_like PF17004.5 KXL46286.1 - 0.025 14.6 0.4 14 5.8 0.0 3.0 3 0 0 3 3 3 0 Putative TPR-like repeat TPR_4 PF07721.14 KXL46286.1 - 0.033 14.8 4.6 0.38 11.5 0.1 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat DNA_pol_D_N PF18018.1 KXL46286.1 - 0.1 12.7 0.0 0.34 11.0 0.0 1.8 1 1 0 1 1 1 0 DNA polymerase delta subunit OB-fold domain Fis1_TPR_C PF14853.6 KXL46286.1 - 0.12 12.5 6.6 6 7.0 0.0 3.7 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 KXL46286.1 - 0.21 11.9 0.9 5.8 7.3 0.1 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 KXL46286.1 - 0.31 10.7 1.5 4.8 6.8 0.3 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 KXL46286.1 - 0.78 9.7 14.1 2.9 7.9 0.3 6.5 8 0 0 8 8 8 0 Tetratricopeptide repeat MR_MLE_C PF13378.6 KXL46289.1 - 6.4e-50 169.8 0.0 9.6e-50 169.2 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KXL46289.1 - 8e-06 26.1 0.0 1.7e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 KXL46289.1 - 0.0075 15.5 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Epimerase PF01370.21 KXL46290.1 - 3.9e-15 56.0 0.1 7.2e-15 55.1 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXL46290.1 - 1.2e-14 54.6 0.1 2.2e-14 53.8 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXL46290.1 - 7e-14 51.5 0.0 9.1e-14 51.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXL46290.1 - 1.9e-09 37.1 0.0 0.0015 17.8 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.13 KXL46290.1 - 9.2e-09 35.2 0.4 1.5e-07 31.2 0.7 2.1 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KXL46290.1 - 2.5e-08 33.7 0.1 3.4e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXL46290.1 - 5e-06 25.9 0.3 6.9e-06 25.4 0.3 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KXL46290.1 - 2.4e-05 23.9 0.4 3.9e-05 23.2 0.4 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL46290.1 - 0.00019 21.4 1.8 0.0015 18.5 1.1 2.3 2 1 0 2 2 2 1 KR domain RmlD_sub_bind PF04321.17 KXL46290.1 - 0.00025 20.3 0.0 0.0031 16.7 0.1 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain Sugar_tr PF00083.24 KXL46291.1 - 1.2e-98 331.0 14.6 1.5e-98 330.7 14.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL46291.1 - 1.1e-23 83.8 5.9 1.1e-23 83.8 5.9 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily SNARE_assoc PF09335.11 KXL46291.1 - 0.064 13.7 10.2 0.047 14.2 1.8 3.7 2 2 1 3 3 3 0 SNARE associated Golgi protein Zn_clus PF00172.18 KXL46292.1 - 1.3e-08 34.9 6.6 1.3e-08 34.9 6.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXL46292.1 - 5.2e-07 29.0 2.2 1.6e-05 24.0 2.2 2.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF326 PF03860.16 KXL46292.1 - 0.045 13.7 2.7 0.11 12.5 2.7 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF326) TolA_bind_tri PF16331.5 KXL46292.1 - 0.065 13.3 2.7 0.2 11.8 1.9 2.2 2 0 0 2 2 2 0 TolA binding protein trimerisation ABC_membrane PF00664.23 KXL46293.1 - 2.9e-54 184.6 5.4 3.6e-54 184.3 5.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KXL46293.1 - 1.1e-33 116.7 0.0 2.4e-33 115.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KXL46293.1 - 0.00032 21.1 0.3 0.003 18.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 KXL46293.1 - 0.0008 18.9 0.0 0.0015 18.0 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXL46293.1 - 0.0017 18.6 0.1 0.015 15.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KXL46293.1 - 0.032 13.8 0.1 0.29 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF3987 PF13148.6 KXL46293.1 - 0.09 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DEAD PF00270.29 KXL46293.1 - 0.14 11.9 0.0 14 5.4 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase CTD_bind PF04818.13 KXL46294.1 - 1.5e-17 64.2 0.0 3e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CREPT PF16566.5 KXL46294.1 - 0.0087 16.2 0.7 0.021 15.0 0.7 1.6 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour FAD_binding_3 PF01494.19 KXL46295.1 - 2.7e-26 92.7 0.0 3.2e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain GST_C PF00043.25 KXL46296.1 - 8.6e-18 64.4 0.0 2.1e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXL46296.1 - 1.4e-09 38.0 0.0 3.1e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXL46296.1 - 3.9e-08 33.5 0.0 9.9e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXL46296.1 - 1.5e-07 31.6 0.0 2.8e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXL46296.1 - 1.3e-06 28.7 0.0 2.5e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXL46296.1 - 0.0053 16.8 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KXL46296.1 - 0.028 14.2 0.0 0.11 12.3 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glyco_hydro_15 PF00723.21 KXL46297.1 - 1.1e-68 232.0 0.0 1.3e-68 231.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Tannase PF07519.11 KXL46298.1 - 3.9e-16 59.0 0.4 5e-16 58.7 0.4 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Aa_trans PF01490.18 KXL46299.1 - 4.7e-37 127.7 33.2 5.3e-37 127.5 33.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Bap31 PF05529.12 KXL46299.1 - 0.35 10.7 4.2 0.18 11.7 1.2 2.1 2 0 0 2 2 2 0 Bap31/Bap29 transmembrane region Nop16 PF09420.10 KXL46300.1 - 8.3e-58 195.9 16.2 9.5e-58 195.7 16.2 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Myb_DNA-binding PF00249.31 KXL46300.1 - 0.072 13.3 0.1 0.15 12.3 0.1 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Oxidored_FMN PF00724.20 KXL46302.1 - 2e-38 132.6 0.0 2.6e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family MFS_1 PF07690.16 KXL46303.1 - 1.7e-11 43.7 34.3 1.5e-09 37.3 20.2 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL46303.1 - 0.0064 15.4 2.0 0.0064 15.4 2.0 3.3 2 1 1 3 3 3 1 Sugar (and other) transporter Trp_oprn_chp PF09534.10 KXL46303.1 - 0.02 14.7 0.3 0.02 14.7 0.3 2.1 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Gly-zipper_YMGG PF13441.6 KXL46303.1 - 0.13 12.0 1.2 0.39 10.5 1.0 1.9 1 1 0 1 1 1 0 YMGG-like Gly-zipper DUF2754 PF10953.8 KXL46303.1 - 0.2 11.9 1.3 0.41 10.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) Peptidase_C78 PF07910.13 KXL46304.1 - 6.5e-42 143.4 0.0 7.8e-42 143.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C78 CBM_20 PF00686.19 KXL46305.1 - 2.9e-31 107.2 0.5 3.2e-31 107.1 0.5 1.0 1 0 0 1 1 1 1 Starch binding domain CBM53 PF16760.5 KXL46305.1 - 0.058 14.0 0.0 0.081 13.5 0.0 1.3 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) MFS_1 PF07690.16 KXL46306.1 - 1.5e-41 142.5 47.3 1.5e-41 142.5 47.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL46306.1 - 1.4e-11 44.0 15.3 1.4e-11 44.0 15.3 3.2 2 2 0 2 2 2 1 Sugar (and other) transporter zf-RING_4 PF14570.6 KXL46309.1 - 1.8e-18 66.1 16.0 3e-18 65.3 16.0 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 KXL46309.1 - 2.9e-07 30.2 0.0 7.3e-07 28.9 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rtf2 PF04641.12 KXL46309.1 - 6.3e-07 29.0 5.0 6.3e-07 29.0 5.0 2.2 3 0 0 3 3 3 1 Rtf2 RING-finger zf-C3HC4_3 PF13920.6 KXL46309.1 - 1.5e-05 24.8 12.0 2.5e-05 24.1 12.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXL46309.1 - 0.00078 19.7 14.2 0.0015 18.8 14.2 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KXL46309.1 - 0.0063 16.4 10.0 0.072 13.0 5.7 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.11 KXL46309.1 - 0.018 15.0 7.2 0.034 14.1 7.2 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-UDP PF14569.6 KXL46309.1 - 0.083 13.0 7.3 0.25 11.5 7.3 1.8 1 0 0 1 1 1 0 Zinc-binding RING-finger Nup35_RRM_2 PF14605.6 KXL46309.1 - 0.22 11.6 0.0 0.39 10.7 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif FYVE PF01363.21 KXL46309.1 - 0.5 10.6 6.1 1.1 9.4 6.1 1.6 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 KXL46309.1 - 1 9.6 9.8 0.79 9.9 8.2 1.6 1 1 0 1 1 1 0 FYVE-type zinc finger zf-C3HC4 PF00097.25 KXL46309.1 - 4.5 7.2 14.8 8.7 6.3 14.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXL46309.1 - 5.1 7.1 14.5 9.3 6.3 14.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Complex1_30kDa PF00329.19 KXL46310.1 - 4.7e-46 156.4 0.0 6.6e-46 155.9 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Bac_rhamnosid6H PF17389.2 KXL46311.1 - 8.7e-122 406.6 0.1 1.2e-121 406.2 0.1 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 KXL46311.1 - 1.2e-45 155.5 0.2 2e-45 154.7 0.2 1.4 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 KXL46311.1 - 2.2e-33 114.2 0.0 4.7e-33 113.2 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 KXL46311.1 - 4.6e-19 68.0 0.0 1e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Sugar_tr PF00083.24 KXL46312.1 - 1.1e-81 275.1 19.4 1.1e-81 275.1 19.4 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL46312.1 - 1.4e-21 76.8 17.8 2.3e-21 76.1 17.8 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXL46312.1 - 0.00011 21.6 3.4 0.00011 21.6 3.4 1.9 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 KXL46312.1 - 0.00044 18.9 12.5 0.0079 14.8 3.0 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein Glyco_hydro_31 PF01055.26 KXL46313.1 - 5.4e-118 395.0 3.4 7e-118 394.6 3.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KXL46313.1 - 8.9e-05 22.7 2.4 0.00033 20.9 0.3 3.0 3 1 0 3 3 3 1 Galactose mutarotase-like AidB_N PF18158.1 KXL46314.1 - 1.4e-19 70.6 0.0 2.6e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 KXL46314.1 - 2.8e-17 63.3 8.2 5.2e-16 59.2 4.5 3.1 1 1 1 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXL46314.1 - 4.8e-12 45.9 0.0 1.1e-11 44.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXL46314.1 - 0.063 13.6 1.5 0.31 11.3 0.2 2.7 2 1 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain ECH_1 PF00378.20 KXL46315.1 - 1.6e-38 132.5 0.0 2e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXL46315.1 - 2.3e-19 70.1 0.0 2.9e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KXL46315.1 - 0.059 13.3 0.0 0.25 11.3 0.0 1.9 2 0 0 2 2 2 0 Peptidase family S49 Fe-ADH PF00465.19 KXL46316.1 - 2.2e-103 345.9 0.0 2.7e-103 345.6 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KXL46316.1 - 2.8e-14 53.4 0.0 8.6e-11 42.0 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Formyl_trans_N PF00551.19 KXL46316.1 - 0.028 14.2 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 Formyl transferase Dehydratase_MU PF02288.15 KXL46316.1 - 0.16 11.8 0.0 0.4 10.6 0.0 1.6 1 0 0 1 1 1 0 Dehydratase medium subunit 2-Hacid_dh_C PF02826.19 KXL46317.1 - 2.9e-54 183.1 0.0 4.3e-54 182.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXL46317.1 - 6e-36 123.1 0.1 1.1e-35 122.2 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 KXL46317.1 - 0.0024 17.6 0.1 0.018 14.8 0.0 2.4 2 0 0 2 2 2 1 ACT domain XdhC_C PF13478.6 KXL46317.1 - 0.044 14.3 0.0 0.33 11.4 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_2 PF03446.15 KXL46317.1 - 0.059 13.5 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase HIM1 PF08732.10 KXL46319.1 - 3.4e-10 39.7 0.0 1.1e-09 38.0 0.0 1.7 1 1 0 1 1 1 1 HIM1 NAD_binding_10 PF13460.6 KXL46319.1 - 9.3e-06 25.6 0.1 1.5e-05 25.0 0.1 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXL46319.1 - 0.0069 15.9 0.1 0.038 13.5 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KXL46319.1 - 0.017 15.6 0.0 0.039 14.4 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DUF1471 PF07338.13 KXL46319.1 - 0.072 13.1 0.2 0.072 13.1 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1471) HECT PF00632.25 KXL46320.1 - 4.7e-79 266.1 0.0 2.3e-78 263.8 0.0 2.0 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) HEAT PF02985.22 KXL46320.1 - 0.0014 18.7 0.4 0.95 9.9 0.1 3.7 3 0 0 3 3 3 1 HEAT repeat Adaptin_N PF01602.20 KXL46320.1 - 0.037 12.6 2.5 0.082 11.5 0.1 2.6 3 0 0 3 3 3 0 Adaptin N terminal region Arm PF00514.23 KXL46320.1 - 0.076 13.1 4.7 59 3.9 0.0 6.0 6 1 1 7 7 7 0 Armadillo/beta-catenin-like repeat RRN3 PF05327.11 KXL46320.1 - 5 5.6 10.8 13 4.2 10.8 1.6 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SKG6 PF08693.10 KXL46321.1 - 0.041 13.3 2.6 0.11 11.9 2.6 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TraQ PF09679.10 KXL46321.1 - 0.044 13.7 1.5 0.06 13.3 0.0 1.9 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) CDC45 PF02724.14 KXL46321.1 - 0.98 7.6 6.9 7.7 4.7 3.8 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF4228 PF14009.6 KXL46321.1 - 0.99 9.8 8.0 2.7 8.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) HCV_NS4a PF01006.20 KXL46323.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a Slp PF03843.13 KXL46326.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein Slp family p450 PF00067.22 KXL46328.1 - 2.1e-63 214.7 0.0 2.8e-63 214.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NmrA PF05368.13 KXL46329.1 - 6.2e-16 58.7 0.0 8.2e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXL46329.1 - 4e-07 30.1 0.0 6.1e-07 29.5 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXL46329.1 - 0.0007 19.1 0.0 0.0028 17.1 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXL46329.1 - 0.016 14.3 0.0 0.034 13.3 0.0 1.5 2 0 0 2 2 2 0 RmlD substrate binding domain DapB_N PF01113.20 KXL46329.1 - 0.13 12.4 0.0 0.64 10.2 0.0 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Ish1 PF10281.9 KXL46329.1 - 3.6 8.0 4.5 1.5 9.2 0.2 2.6 4 0 0 4 4 4 0 Putative stress-responsive nuclear envelope protein DUF1295 PF06966.12 KXL46330.1 - 3.7e-42 144.5 8.2 5.1e-42 144.0 8.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KXL46330.1 - 0.64 10.5 0.0 0.64 10.5 0.0 2.6 3 1 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Shisa PF13908.6 KXL46331.1 - 0.16 12.2 4.3 0.56 10.4 0.5 2.4 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator LRR_6 PF13516.6 KXL46332.1 - 7.4e-10 38.1 24.1 0.0029 17.5 0.2 7.9 9 0 0 9 9 9 3 Leucine Rich repeat F-box-like PF12937.7 KXL46332.1 - 8.4e-10 38.4 0.6 2.3e-09 37.0 0.6 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXL46332.1 - 2.2e-09 36.9 0.7 1.8e-08 34.1 0.5 2.5 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 KXL46332.1 - 3.6e-07 30.4 18.4 0.0019 18.6 0.3 5.7 3 2 3 6 6 6 4 Leucine Rich repeats (2 copies) PRANC PF09372.10 KXL46332.1 - 0.063 13.6 0.0 0.39 11.1 0.0 2.4 2 0 0 2 2 2 0 PRANC domain LRR_1 PF00560.33 KXL46332.1 - 0.34 11.6 27.4 0.49 11.1 0.7 7.2 8 0 0 8 8 8 0 Leucine Rich Repeat ABC_membrane PF00664.23 KXL46335.1 - 6.6e-48 163.7 8.8 7.3e-48 163.6 8.8 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF2628 PF10947.8 KXL46335.1 - 0.026 14.9 4.5 0.097 13.0 2.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2628) Cu_bind_CorA PF18252.1 KXL46335.1 - 0.032 13.8 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 Copper(I)-binding protein CorA Phage_holin_3_6 PF07332.11 KXL46335.1 - 0.072 13.1 5.4 1.9 8.6 2.5 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III PrgI PF12666.7 KXL46335.1 - 0.13 12.9 2.1 0.19 12.5 0.4 2.0 2 0 0 2 2 2 0 PrgI family protein ABC_membrane PF00664.23 KXL46337.1 - 4.4e-20 72.5 0.8 5.9e-20 72.0 0.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF4169 PF13770.6 KXL46337.1 - 0.016 15.5 0.5 0.03 14.6 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4169) Acyltransferase PF01553.21 KXL46338.1 - 7.6e-27 93.6 0.0 1.2e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KXL46338.1 - 6.3e-15 55.0 0.1 1.3e-14 54.0 0.1 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus SPR1 PF15356.6 KXL46338.1 - 0.043 14.3 2.0 0.088 13.3 2.0 1.4 1 0 0 1 1 1 0 Psoriasis susceptibility locus 2 NAD_kinase PF01513.21 KXL46339.1 - 2.5e-46 158.2 0.0 3.5e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DER1 PF04511.15 KXL46340.1 - 2.2e-24 86.4 10.4 2.2e-13 50.5 0.3 2.2 2 0 0 2 2 2 2 Der1-like family Rit1_C PF17184.4 KXL46341.1 - 1.8e-103 345.8 0.0 2.3e-103 345.4 0.0 1.1 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 KXL46341.1 - 2.4e-32 111.5 0.0 5e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 Rit1 DUSP-like domain Radical_SAM_C PF16199.5 KXL46342.1 - 5.1e-32 109.8 0.1 9.4e-32 108.9 0.1 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KXL46342.1 - 8.2e-18 65.3 0.0 2.3e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KXL46342.1 - 1.2e-08 35.1 0.1 2.5e-08 34.2 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXL46342.1 - 2.8e-05 24.0 0.0 6.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXL46342.1 - 0.02 15.3 0.0 0.041 14.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SARAF PF06682.12 KXL46343.1 - 1.1e-106 357.3 0.5 1.3e-106 357.1 0.5 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis NDUF_B12 PF08122.12 KXL46343.1 - 0.087 12.9 0.7 0.48 10.5 0.0 2.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family Insulin_TMD PF17870.1 KXL46344.1 - 0.003 17.6 1.9 0.43 10.7 0.0 2.2 2 0 0 2 2 2 1 Insulin receptor trans-membrane segment DUF1282 PF06930.12 KXL46344.1 - 0.0042 16.9 0.3 0.005 16.6 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) Yip1 PF04893.17 KXL46344.1 - 0.013 15.2 1.5 0.016 15.0 1.5 1.1 1 0 0 1 1 1 0 Yip1 domain MIG-14_Wnt-bd PF06664.12 KXL46344.1 - 0.016 14.4 0.1 0.018 14.2 0.1 1.1 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion DUF202 PF02656.15 KXL46344.1 - 0.024 15.1 1.5 0.046 14.2 1.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF202) OppC_N PF12911.7 KXL46344.1 - 0.15 12.1 1.2 8.4 6.5 0.0 2.2 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C TMEMspv1-c74-12 PF11044.8 KXL46344.1 - 0.25 11.4 3.0 0.51 10.4 0.0 2.1 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF2207 PF09972.9 KXL46344.1 - 0.25 10.0 1.2 0.27 10.0 1.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Adap_comp_sub PF00928.21 KXL46345.1 - 2.7e-84 282.7 0.0 3.4e-84 282.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KXL46345.1 - 0.00028 20.8 0.2 0.00053 19.9 0.2 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KXL46345.1 - 0.004 16.6 0.2 0.0074 15.8 0.2 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain UCR_hinge PF02320.16 KXL46346.1 - 0.063 13.5 1.0 0.11 12.7 1.0 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein Ras PF00071.22 KXL46347.1 - 2.5e-47 160.5 0.3 2.9e-47 160.3 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXL46347.1 - 8.1e-16 58.3 0.1 1.1e-15 57.9 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXL46347.1 - 3.3e-09 36.4 0.0 3.5e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KXL46347.1 - 1.5e-05 24.5 0.2 2.4e-05 23.8 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KXL46347.1 - 1.7e-05 24.8 0.2 0.0033 17.3 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KXL46347.1 - 8.5e-05 22.6 0.1 0.00015 21.8 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXL46347.1 - 0.00019 21.0 0.1 0.0023 17.5 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KXL46347.1 - 0.0026 17.3 0.5 0.055 13.0 0.0 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B AAA_14 PF13173.6 KXL46347.1 - 0.029 14.4 0.1 0.046 13.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain Elf1 PF05129.13 KXL46348.1 - 6.6e-26 90.2 2.1 8.7e-26 89.8 2.1 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Zn_ribbon_SprT PF17283.2 KXL46348.1 - 0.0039 17.1 0.6 0.0061 16.4 0.6 1.3 1 0 0 1 1 1 1 SprT-like zinc ribbon domain Vps36-NZF-N PF16988.5 KXL46348.1 - 0.06 12.7 0.2 0.11 11.9 0.2 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Fer4_18 PF13746.6 KXL46348.1 - 0.12 12.6 1.3 0.37 11.0 0.3 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Zn-ribbon_8 PF09723.10 KXL46348.1 - 0.21 11.8 2.1 3.4 7.8 0.3 2.3 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2H2_4 PF13894.6 KXL46348.1 - 0.53 11.3 3.8 2.3 9.3 0.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger GTP_CH_N PF12471.8 KXL46349.1 - 3.6e-93 310.7 0.0 6.3e-93 309.9 0.0 1.4 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 KXL46349.1 - 4.3e-18 65.4 0.0 6.6e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Fib_alpha PF08702.10 KXL46350.1 - 0.03 14.5 7.6 0.038 14.2 7.6 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Golgin_A5 PF09787.9 KXL46350.1 - 0.05 13.1 13.2 0.066 12.7 13.2 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Filaggrin PF03516.13 KXL46350.1 - 0.12 13.2 11.6 0.43 11.3 11.4 2.1 1 1 0 1 1 1 0 Filaggrin Herpes_UL25 PF01499.16 KXL46350.1 - 0.24 9.9 5.3 0.25 9.8 5.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family MRP-S27 PF10037.9 KXL46350.1 - 0.34 9.7 10.3 0.41 9.5 10.3 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Exonuc_VII_L PF02601.15 KXL46350.1 - 0.4 10.2 10.2 0.48 9.9 10.2 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit ISG65-75 PF11727.8 KXL46350.1 - 0.44 9.7 8.5 0.55 9.4 8.5 1.0 1 0 0 1 1 1 0 Invariant surface glycoprotein MPS2 PF17060.5 KXL46350.1 - 0.97 8.6 7.8 1.6 7.9 7.5 1.5 1 1 0 1 1 1 0 Monopolar spindle protein 2 UPF0242 PF06785.11 KXL46350.1 - 1 9.4 11.0 1.3 9.1 11.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Nup88 PF10168.9 KXL46350.1 - 1.1 7.0 8.6 1.2 6.9 8.6 1.1 1 0 0 1 1 1 0 Nuclear pore component TMPIT PF07851.13 KXL46350.1 - 1.2 8.3 7.8 1.4 8.1 7.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein ZapB PF06005.12 KXL46350.1 - 8.9 6.8 15.8 76 3.9 13.3 2.4 1 1 1 2 2 2 0 Cell division protein ZapB Adenylsucc_synt PF00709.21 KXL46351.1 - 4.4e-170 566.1 0.0 4.9e-170 566.0 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase HPP PF04982.13 KXL46353.1 - 1.6e-38 131.6 7.3 2.5e-38 131.0 7.3 1.3 1 0 0 1 1 1 1 HPP family ORC2 PF04084.14 KXL46354.1 - 4.7e-116 387.3 0.0 6e-116 387.0 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Drc1-Sld2 PF11719.8 KXL46354.1 - 0.0012 18.5 4.5 0.0016 18.1 4.5 1.2 1 0 0 1 1 1 1 DNA replication and checkpoint protein ORC6 PF05460.13 KXL46354.1 - 0.028 13.7 9.6 0.063 12.5 9.6 1.5 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) ARD PF03079.14 KXL46355.1 - 8.3e-48 162.5 0.0 9.7e-48 162.3 0.0 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KXL46355.1 - 6e-10 38.7 0.0 1.1e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KXL46355.1 - 3.4e-07 30.2 0.0 5.3e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 KXL46355.1 - 0.0023 17.6 0.0 0.0036 16.9 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 KXL46355.1 - 0.013 15.2 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DMSP_lyase PF16867.5 KXL46355.1 - 0.026 14.2 0.1 0.043 13.4 0.1 1.3 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase Cupin_6 PF12852.7 KXL46355.1 - 0.033 13.9 0.0 0.044 13.5 0.0 1.1 1 0 0 1 1 1 0 Cupin Pet127 PF08634.10 KXL46356.1 - 2.4e-117 391.2 2.7 5.3e-117 390.1 2.7 1.6 1 0 0 1 1 1 1 Mitochondrial protein Pet127 MFS_2 PF13347.6 KXL46357.1 - 6.2e-11 41.5 3.9 2.6e-10 39.5 1.7 2.7 3 0 0 3 3 3 1 MFS/sugar transport protein MFS_1_like PF12832.7 KXL46357.1 - 0.0018 17.2 2.7 0.0041 16.0 1.8 2.0 1 1 0 1 1 1 1 MFS_1 like family G6PD_C PF02781.16 KXL46358.1 - 2.9e-114 381.2 0.0 6.6e-114 380.0 0.0 1.5 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KXL46358.1 - 1.9e-62 211.0 0.0 6.7e-62 209.3 0.0 1.8 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain UL97 PF06734.12 KXL46359.1 - 0.099 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 UL97 Ribosomal_L35Ae PF01247.18 KXL46360.1 - 1.1e-43 147.3 1.0 1.2e-43 147.1 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 KXL46360.1 - 0.0012 19.1 0.1 0.13 12.5 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain ABC_tran PF00005.27 KXL46362.1 - 2.6e-35 121.9 0.0 4.1e-35 121.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KXL46362.1 - 2.3e-07 30.5 0.6 3.2e-05 23.5 0.3 2.3 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 KXL46362.1 - 4e-05 24.1 0.1 0.12 12.8 0.1 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 KXL46362.1 - 0.00059 19.7 0.0 0.034 14.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KXL46362.1 - 0.00061 20.2 0.4 0.0024 18.3 0.3 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXL46362.1 - 0.00082 19.7 0.1 0.0065 16.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 KXL46362.1 - 0.0016 18.4 0.0 0.0049 16.8 0.0 1.7 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_30 PF13604.6 KXL46362.1 - 0.0047 16.7 0.1 0.15 11.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KXL46362.1 - 0.018 15.0 0.0 0.038 13.9 0.0 1.5 2 0 0 2 2 2 0 RsgA GTPase ABC_ATPase PF09818.9 KXL46362.1 - 0.018 13.9 0.1 0.031 13.1 0.1 1.4 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_15 PF13175.6 KXL46362.1 - 0.025 14.3 0.0 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KXL46362.1 - 0.027 14.2 0.0 0.065 13.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 KXL46362.1 - 0.045 13.8 0.0 0.41 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KXL46362.1 - 0.058 13.4 0.0 0.74 9.8 0.0 2.3 1 1 0 2 2 2 0 AAA domain PRK PF00485.18 KXL46362.1 - 0.059 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_7 PF12775.7 KXL46362.1 - 0.06 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 KXL46362.1 - 0.065 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 KXL46362.1 - 0.069 13.4 1.0 0.75 10.1 1.0 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Mg_chelatase PF01078.21 KXL46362.1 - 0.12 11.7 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KXL46362.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain MRNIP PF15749.5 KXL46363.1 - 0.06 14.1 5.1 0.075 13.8 5.1 1.2 1 0 0 1 1 1 0 MRN-interacting protein zf-CHY PF05495.12 KXL46363.1 - 0.088 13.3 1.9 0.088 13.3 1.9 1.9 1 1 1 2 2 2 0 CHY zinc finger OAR PF03826.17 KXL46363.1 - 0.27 11.1 0.2 0.27 11.1 0.2 2.1 2 0 0 2 2 2 0 OAR domain F-box PF00646.33 KXL46364.1 - 5.2e-05 23.0 1.3 0.00016 21.4 1.3 1.9 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 KXL46364.1 - 0.052 14.0 1.2 3.1 8.4 0.1 3.6 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KXL46364.1 - 0.32 10.9 1.6 0.78 9.7 1.6 1.6 1 0 0 1 1 1 0 F-box-like Mitofilin PF09731.9 KXL46367.1 - 1.7e-118 397.2 20.4 3e-100 336.9 14.5 2.0 1 1 0 2 2 2 2 Mitochondrial inner membrane protein DUF1515 PF07439.11 KXL46367.1 - 0.024 14.6 7.3 0.65 10.1 0.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) Exonuc_VII_L PF02601.15 KXL46367.1 - 1.4 8.4 10.5 2.1 7.8 10.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Baculo_PEP_C PF04513.12 KXL46367.1 - 2.1 8.4 8.8 0.31 11.1 1.5 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MFS_1 PF07690.16 KXL46368.1 - 4.4e-20 71.9 64.2 4.9e-17 61.9 44.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5315 PF17242.2 KXL46369.1 - 4.6e-22 77.6 3.3 1.2e-21 76.3 3.3 1.7 1 0 0 1 1 1 1 Disordered region of unknown function (DUF5315) Cluap1 PF10234.9 KXL46369.1 - 0.18 11.2 10.9 0.071 12.5 8.5 1.5 1 1 0 1 1 1 0 Clusterin-associated protein-1 Amidase PF01425.21 KXL46370.1 - 2.6e-78 264.0 0.2 6.4e-75 252.8 0.1 2.0 2 0 0 2 2 2 2 Amidase Herpes_DNAp_acc PF04929.12 KXL46372.1 - 2.5 7.0 4.9 4.4 6.2 4.9 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor VSG_B PF13206.6 KXL46373.1 - 0.24 10.6 3.1 0.28 10.4 3.1 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain RRM_1 PF00076.22 KXL46374.1 - 5.4e-19 67.8 0.0 7.9e-19 67.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXL46374.1 - 0.0005 19.7 0.0 0.00071 19.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3431 PF11913.8 KXL46375.1 - 1.5e-84 283.1 0.0 2e-84 282.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) GDPD PF03009.17 KXL46376.1 - 1.4e-30 106.9 0.0 1.5e-29 103.6 0.0 2.0 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 KXL46376.1 - 0.0028 18.1 1.1 0.66 10.5 1.3 2.8 2 1 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family Tubulin PF00091.25 KXL46377.1 - 6.6e-67 225.5 0.0 9.1e-67 225.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KXL46377.1 - 3.1e-41 140.5 0.1 9.2e-41 138.9 0.0 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KXL46377.1 - 5.7e-08 33.1 0.0 1.1e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain DUF4012 PF13196.6 KXL46377.1 - 0.08 13.4 0.1 0.16 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4012) Tubulin_3 PF14881.6 KXL46377.1 - 0.16 11.7 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Tubulin domain Aldo_ket_red PF00248.21 KXL46379.1 - 1.1e-53 182.4 0.0 1.3e-53 182.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family EamA PF00892.20 KXL46380.1 - 2.1e-06 28.0 29.6 5.2e-06 26.7 2.3 3.0 3 0 0 3 3 3 2 EamA-like transporter family CSG2 PF16965.5 KXL46380.1 - 3e-06 26.5 5.8 2.1e-05 23.7 6.1 2.2 1 1 1 2 2 2 1 Ceramide synthase regulator Nuc_sug_transp PF04142.15 KXL46380.1 - 0.0048 16.1 0.0 0.0079 15.4 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter GCS PF03074.16 KXL46381.1 - 3e-176 586.2 0.0 3.6e-176 585.9 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GATA PF00320.27 KXL46382.1 - 3.6e-15 55.3 5.3 6.4e-15 54.5 5.3 1.4 1 0 0 1 1 1 1 GATA zinc finger zinc_ribbon_9 PF14369.6 KXL46382.1 - 0.44 10.8 1.6 0.94 9.8 1.6 1.5 1 0 0 1 1 1 0 zinc-ribbon Hexapep PF00132.24 KXL46384.1 - 6.5e-12 44.7 8.1 2.1e-06 27.2 0.1 4.6 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KXL46384.1 - 1.2e-05 24.9 5.8 0.0062 16.3 0.3 3.9 3 1 1 4 4 4 4 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KXL46384.1 - 0.011 14.7 0.2 0.015 14.3 0.2 1.3 1 1 0 1 1 1 0 L-fucokinase PI-PLC-X PF00388.19 KXL46385.1 - 3.8e-07 29.8 0.0 6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain NmrA PF05368.13 KXL46386.1 - 1.6e-29 103.2 0.0 1.8e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXL46386.1 - 7.8e-08 32.4 0.0 1.2e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXL46386.1 - 0.006 16.1 0.1 0.012 15.1 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXL46386.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.19 KXL46386.1 - 0.14 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Meth_synt_2 PF01717.18 KXL46387.1 - 1.5e-09 37.6 0.0 2.1e-07 30.6 0.0 2.8 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain ADH_N PF08240.12 KXL46388.1 - 7.7e-27 93.3 2.4 1.9e-26 92.1 2.4 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXL46388.1 - 4.4e-22 78.4 0.3 8.5e-22 77.5 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXL46388.1 - 0.00066 19.0 0.6 0.0012 18.2 0.6 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 KXL46388.1 - 0.0019 18.5 0.1 0.0033 17.7 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Imm70 PF15601.6 KXL46388.1 - 0.044 13.3 0.0 0.35 10.4 0.0 2.1 2 0 0 2 2 2 0 Immunity protein 70 Glu_dehyd_C PF16912.5 KXL46388.1 - 0.067 12.7 0.0 0.32 10.5 0.0 2.0 1 1 0 1 1 1 0 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 KXL46388.1 - 0.086 12.4 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 KXL46388.1 - 0.1 13.2 0.2 0.33 11.6 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 KXL46388.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 KXL46388.1 - 0.15 11.4 0.1 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain p450 PF00067.22 KXL46389.1 - 9.6e-69 232.3 0.0 1.2e-68 232.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ATP-synt_C PF00137.21 KXL46390.1 - 3e-35 120.4 35.6 5e-22 78.0 15.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C AMP-binding PF00501.28 KXL46392.1 - 9.1e-69 232.1 0.1 1.1e-68 231.8 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXL46392.1 - 3.7e-19 69.5 0.1 8.3e-19 68.4 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BAG PF02179.16 KXL46393.1 - 7.3e-18 64.8 0.6 1.2e-17 64.1 0.6 1.4 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 KXL46393.1 - 5.8e-06 26.0 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_5 PF18037.1 KXL46393.1 - 0.081 13.3 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain Ribosomal_L13 PF00572.18 KXL46394.1 - 2.3e-10 40.8 0.0 2.4e-08 34.3 0.0 2.4 1 1 0 1 1 1 1 Ribosomal protein L13 AreA_N PF07573.11 KXL46395.1 - 0.0061 17.2 0.1 0.13 13.0 0.0 2.3 2 0 0 2 2 2 1 Nitrogen regulatory protein AreA N terminus TPR_12 PF13424.6 KXL46396.1 - 0.00063 20.0 0.3 0.0017 18.6 0.3 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXL46396.1 - 1.9 8.9 3.2 2.1 8.8 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat PCMT PF01135.19 KXL46397.1 - 0.044 13.5 0.0 0.051 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF3535 PF12054.8 KXL46401.1 - 1.1e-123 413.8 0.8 6.5e-122 407.9 0.0 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 KXL46401.1 - 1.2e-63 215.0 0.0 2e-62 211.0 0.0 2.4 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXL46401.1 - 1.3e-19 70.6 0.0 6.5e-19 68.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HEAT PF02985.22 KXL46401.1 - 5.5e-18 63.5 20.3 0.004 17.3 0.0 11.5 12 0 0 12 12 12 6 HEAT repeat HEAT_2 PF13646.6 KXL46401.1 - 1.5e-06 28.5 16.8 0.00072 19.9 0.1 7.3 7 1 0 8 8 8 1 HEAT repeats Vac14_Fab1_bd PF12755.7 KXL46401.1 - 4e-06 27.3 0.0 0.022 15.4 0.0 3.8 3 1 0 3 3 3 2 Vacuolar 14 Fab1-binding region TAF6_C PF07571.13 KXL46401.1 - 0.0006 20.1 0.1 3.2 8.1 0.0 5.8 6 0 0 6 6 6 1 TAF6 C-terminal HEAT repeat domain CLASP_N PF12348.8 KXL46401.1 - 0.0012 18.4 0.0 1 8.9 0.0 3.4 2 1 1 3 3 3 1 CLASP N terminal ERCC3_RAD25_C PF16203.5 KXL46401.1 - 0.14 11.3 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase HEAT_EZ PF13513.6 KXL46401.1 - 0.62 10.6 26.1 3.4 8.3 0.1 9.0 9 1 0 9 9 9 0 HEAT-like repeat Ribosomal_L28 PF00830.19 KXL46403.1 - 0.072 13.3 0.0 9.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Ribosomal L28 family DUF4603 PF15376.6 KXL46403.1 - 0.086 10.2 0.2 0.13 9.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) TnpV PF14198.6 KXL46403.1 - 0.14 12.1 0.5 0.36 10.8 0.0 1.8 2 0 0 2 2 2 0 Transposon-encoded protein TnpV zf-CCCH PF00642.24 KXL46403.1 - 0.7 9.9 15.2 0.32 11.0 3.4 3.0 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Abhydrolase_1 PF00561.20 KXL46404.1 - 8.2e-15 55.1 0.0 3.2e-14 53.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXL46404.1 - 1e-12 47.8 0.0 3.2e-12 46.2 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXL46404.1 - 2.4e-11 44.7 0.0 3.3e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXL46404.1 - 0.0014 18.1 0.1 1.3 8.4 0.0 2.4 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KXL46404.1 - 0.0023 17.8 0.1 1.9 8.2 0.0 2.8 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase Esterase PF00756.20 KXL46404.1 - 0.0067 16.1 0.0 0.0098 15.6 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 KXL46404.1 - 0.011 15.9 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 KXL46404.1 - 0.031 14.0 0.6 0.12 12.1 0.5 1.8 1 1 1 2 2 2 0 PGAP1-like protein DLH PF01738.18 KXL46404.1 - 0.05 13.1 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 KXL46404.1 - 0.052 13.4 0.0 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold UPF0227 PF05728.12 KXL46404.1 - 0.1 12.5 0.0 5.3 6.9 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0227) DUF1100 PF06500.11 KXL46404.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) HET PF06985.11 KXL46407.1 - 5.9e-30 104.5 0.1 1.6e-28 99.9 0.1 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CoA_binding_2 PF13380.6 KXL46408.1 - 0.079 13.5 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 CoA binding domain MIP PF00230.20 KXL46409.1 - 1.8e-43 148.9 16.3 2e-43 148.7 16.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein CBM_20 PF00686.19 KXL46410.1 - 0.032 14.1 0.0 0.042 13.8 0.0 1.1 1 0 0 1 1 1 0 Starch binding domain UAA PF08449.11 KXL46411.1 - 1e-45 156.3 15.8 1.9e-45 155.4 15.8 1.4 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 KXL46411.1 - 7.2e-08 32.0 2.4 0.00016 21.0 0.1 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.20 KXL46411.1 - 4.2e-07 30.2 25.2 0.00067 19.8 9.4 3.2 2 2 1 3 3 3 2 EamA-like transporter family TPT PF03151.16 KXL46411.1 - 0.23 10.8 9.0 0.43 9.9 1.8 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family Yippee-Mis18 PF03226.14 KXL46412.1 - 1.8e-17 63.4 1.8 2.1e-17 63.2 1.8 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2039 PF10217.9 KXL46412.1 - 0.022 15.1 0.7 0.022 15.1 0.7 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) RIG-I_C-RD PF11648.8 KXL46412.1 - 0.033 14.4 1.9 0.05 13.8 1.9 1.3 1 0 0 1 1 1 0 C-terminal domain of RIG-I Lactamase_B PF00753.27 KXL46414.1 - 0.00011 22.3 0.1 0.0017 18.4 0.0 2.0 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily MbtH PF03621.13 KXL46415.1 - 0.038 13.4 0.0 0.15 11.5 0.0 1.9 2 0 0 2 2 2 0 MbtH-like protein Zn_clus PF00172.18 KXL46416.1 - 4e-09 36.4 7.3 4e-09 36.4 7.3 2.8 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXL46416.1 - 8.1e-05 21.8 0.1 0.00014 21.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DJ-1_PfpI PF01965.24 KXL46419.1 - 0.00015 21.6 0.0 0.00018 21.4 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family GATase_5 PF13507.6 KXL46419.1 - 0.083 12.0 0.0 0.097 11.7 0.0 1.1 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Aminotran_1_2 PF00155.21 KXL46420.1 - 1.9e-82 277.4 0.0 2.2e-82 277.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Pectinesterase PF01095.19 KXL46421.1 - 8.2e-41 139.7 1.8 1e-40 139.3 1.8 1.0 1 0 0 1 1 1 1 Pectinesterase CDO_I PF05995.12 KXL46422.1 - 1.3e-45 154.8 0.1 1.5e-45 154.5 0.1 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 KXL46422.1 - 0.00017 21.1 0.7 0.00053 19.5 0.7 1.9 1 1 0 1 1 1 1 PCO_ADO Auxin_BP PF02041.16 KXL46422.1 - 0.06 13.0 0.0 0.071 12.8 0.0 1.2 1 0 0 1 1 1 0 Auxin binding protein Sod_Fe_C PF02777.18 KXL46423.1 - 5.1e-40 135.8 0.1 1.3e-39 134.5 0.1 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KXL46423.1 - 3e-30 104.5 0.2 5.1e-30 103.8 0.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain MFS_1 PF07690.16 KXL46424.1 - 7.3e-27 94.2 51.9 2.6e-22 79.2 30.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXL46424.1 - 0.00019 19.8 0.0 0.00064 18.1 0.0 1.8 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF3262 PF11660.8 KXL46424.1 - 7.2 7.1 8.5 13 6.2 0.2 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3262) E1-E2_ATPase PF00122.20 KXL46425.1 - 1.2e-15 57.5 2.0 4.5e-15 55.6 0.0 2.8 2 1 1 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KXL46425.1 - 9.2e-12 45.0 3.6 3.2e-07 30.3 0.1 2.6 1 1 1 2 2 2 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KXL46425.1 - 1.4e-11 45.1 0.0 5.8e-11 43.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cellulase PF00150.18 KXL46427.1 - 7.5e-18 64.9 3.3 1.1e-17 64.4 3.3 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KXL46427.1 - 5.9e-05 22.3 0.0 7.7e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4038 PF13204.6 KXL46427.1 - 0.0032 17.1 1.2 0.0048 16.6 0.6 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4038) Glyco_hydro_42 PF02449.15 KXL46427.1 - 0.0081 15.5 0.1 0.15 11.4 0.1 2.1 2 0 0 2 2 2 1 Beta-galactosidase Glyco_hydro_97 PF10566.9 KXL46427.1 - 0.03 13.6 0.0 0.052 12.8 0.0 1.4 1 0 0 1 1 1 0 Glycoside hydrolase 97 Amidohydro_2 PF04909.14 KXL46429.1 - 2.3e-18 67.0 0.2 1.2e-17 64.6 0.2 1.9 1 1 0 1 1 1 1 Amidohydrolase DHDPS PF00701.22 KXL46430.1 - 6.1e-31 107.2 0.0 8.6e-31 106.7 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Aldolase PF01081.19 KXL46430.1 - 0.096 12.1 0.0 5.2 6.4 0.0 2.3 2 0 0 2 2 2 0 KDPG and KHG aldolase ABC_membrane PF00664.23 KXL46431.1 - 3.6e-24 85.9 14.1 2.1e-22 80.1 3.7 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXL46431.1 - 2.3e-19 70.3 0.0 4.3e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXL46431.1 - 0.00048 20.0 0.6 0.033 14.0 0.1 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXL46431.1 - 0.0015 18.0 0.1 0.17 11.3 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KXL46431.1 - 0.0041 17.7 0.0 0.0065 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KXL46431.1 - 0.013 14.5 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 KXL46431.1 - 0.017 14.8 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KXL46431.1 - 0.045 14.1 0.2 0.11 12.8 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 KXL46431.1 - 0.048 13.7 0.2 0.089 12.8 0.2 1.4 1 0 0 1 1 1 0 Dynamin family RsgA_GTPase PF03193.16 KXL46431.1 - 0.072 13.0 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 KXL46431.1 - 0.11 12.2 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF87 PF01935.17 KXL46431.1 - 0.14 12.3 0.1 0.29 11.2 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain EF-1_beta_acid PF10587.9 KXL46432.1 - 0.033 14.6 2.7 0.033 14.6 2.7 2.4 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region DUF4011 PF13195.6 KXL46432.1 - 0.082 12.8 1.0 0.14 12.1 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) Med21 PF11221.8 KXL46432.1 - 2.8 8.2 7.2 15 5.9 7.2 2.1 1 1 0 1 1 1 0 Subunit 21 of Mediator complex HMG_CoA_synt_C PF08540.10 KXL46433.1 - 3.8e-103 345.0 0.1 4.8e-103 344.6 0.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KXL46433.1 - 1.2e-95 318.3 0.1 1.9e-95 317.7 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal LapA_dom PF06305.11 KXL46434.1 - 0.13 12.1 1.2 0.23 11.3 1.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain RRM_1 PF00076.22 KXL46436.1 - 1.4e-10 40.8 0.0 2.6e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2389 PF09493.10 KXL46437.1 - 0.067 13.8 0.1 0.067 13.8 0.1 1.8 2 0 0 2 2 2 0 Tryptophan-rich protein (DUF2389) Fungal_trans PF04082.18 KXL46438.1 - 5e-12 45.4 0.1 9.9e-12 44.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL46438.1 - 0.00018 21.6 10.4 0.0005 20.1 10.4 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain vATP-synt_E PF01991.18 KXL46439.1 - 2.2e-61 206.8 11.7 2.7e-61 206.5 11.7 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit PACT_coil_coil PF10495.9 KXL46439.1 - 0.032 14.8 0.8 0.032 14.8 0.8 1.7 2 0 0 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein NTS PF15447.6 KXL46439.1 - 0.14 12.7 5.1 4.5 7.8 0.5 2.5 2 0 0 2 2 2 0 N-terminal segments of PfEMP1 IBB PF01749.20 KXL46439.1 - 1.3 9.5 8.5 2.5 8.6 0.2 2.4 2 0 0 2 2 2 0 Importin beta binding domain Pox_G9-A16 PF03003.16 KXL46440.1 - 1.3 8.7 5.6 0.41 10.4 0.4 2.1 2 0 0 2 2 2 0 Pox virus entry-fusion-complex G9/A16 Fungal_trans_2 PF11951.8 KXL46441.1 - 5.9e-21 74.7 0.5 8.3e-21 74.2 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL46441.1 - 1.7e-08 34.4 11.7 2.9e-08 33.7 11.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_7 PF03441.14 KXL46442.1 - 1.4e-76 256.5 0.3 2.1e-76 255.9 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KXL46442.1 - 1.1e-41 142.6 0.2 1.7e-41 142.0 0.2 1.2 1 0 0 1 1 1 1 DNA photolyase Abhydrolase_6 PF12697.7 KXL46444.1 - 0.06 13.9 12.2 0.12 13.0 12.2 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family MoCF_biosynth PF00994.24 KXL46447.1 - 8e-32 109.9 0.0 1.4e-31 109.1 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain Cofilin_ADF PF00241.20 KXL46448.1 - 3.8e-16 59.0 0.0 5.1e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Ras PF00071.22 KXL46449.1 - 2.6e-59 199.5 0.1 3e-59 199.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXL46449.1 - 6.1e-20 71.6 0.0 9.4e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXL46449.1 - 2.4e-07 30.4 0.0 2.6e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXL46449.1 - 4e-05 23.2 0.0 0.00039 20.0 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KXL46449.1 - 7.3e-05 22.7 0.2 0.19 11.6 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1_Xtn PF16897.5 KXL46449.1 - 0.0017 18.3 0.0 0.0033 17.4 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KXL46449.1 - 0.0049 16.9 0.0 0.0072 16.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXL46449.1 - 0.015 14.8 0.0 0.033 13.7 0.0 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B Lon_C PF05362.13 KXL46450.1 - 2.1e-69 233.2 0.4 4.2e-69 232.2 0.4 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KXL46450.1 - 7.9e-31 107.5 0.1 2.2e-30 106.1 0.1 1.8 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KXL46450.1 - 3.4e-24 85.7 0.0 1.3e-23 83.9 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXL46450.1 - 2.3e-08 34.1 0.0 1e-07 32.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 KXL46450.1 - 2e-07 30.9 0.0 4.9e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 KXL46450.1 - 1.5e-06 28.7 0.2 3.5e-05 24.2 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_3 PF07726.11 KXL46450.1 - 0.00015 21.7 0.0 0.00043 20.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 KXL46450.1 - 0.00025 21.2 0.0 0.00064 19.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KXL46450.1 - 0.00027 20.7 0.0 0.00067 19.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 KXL46450.1 - 0.0003 20.6 0.0 0.0016 18.2 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXL46450.1 - 0.0006 20.1 0.0 0.0091 16.3 0.0 2.8 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 KXL46450.1 - 0.0015 17.8 0.0 0.0031 16.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KXL46450.1 - 0.0015 18.7 0.6 0.0046 17.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KXL46450.1 - 0.014 15.0 0.1 0.12 11.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KXL46450.1 - 0.02 14.3 0.1 0.058 12.8 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KXL46450.1 - 0.03 14.7 0.0 0.067 13.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 KXL46450.1 - 0.031 13.8 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 KXL46450.1 - 0.035 13.5 0.0 0.08 12.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein TsaE PF02367.17 KXL46450.1 - 0.045 13.8 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 KXL46450.1 - 0.048 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain ATPase_2 PF01637.18 KXL46450.1 - 0.052 13.5 0.0 0.17 11.7 0.0 1.9 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KXL46450.1 - 0.053 14.1 0.1 0.16 12.5 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KXL46450.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXL46450.1 - 0.055 13.4 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 KXL46450.1 - 0.055 13.5 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_PrkA PF08298.11 KXL46450.1 - 0.076 11.9 0.1 0.71 8.7 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain AAA_23 PF13476.6 KXL46450.1 - 0.097 13.2 0.0 0.097 13.2 0.0 3.2 2 1 1 3 3 1 0 AAA domain AAA_11 PF13086.6 KXL46450.1 - 0.12 12.1 0.1 0.12 12.1 0.1 2.0 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 KXL46450.1 - 0.12 12.0 0.1 0.22 11.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain Laps PF10169.9 KXL46450.1 - 4.4 7.9 8.6 2 9.0 0.5 2.5 1 1 1 2 2 2 0 Learning-associated protein AtuA PF07287.11 KXL46451.1 - 2e-128 428.0 0.0 2.4e-128 427.8 0.0 1.0 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Mito_carr PF00153.27 KXL46452.1 - 1.2e-44 150.1 5.0 2e-16 59.7 0.0 4.2 3 1 1 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 KXL46452.1 - 0.0016 17.7 0.7 0.051 12.7 0.1 2.2 2 0 0 2 2 2 2 Gammaproteobacterial serine protease Ribosomal_L26 PF16906.5 KXL46453.1 - 7.4e-38 128.9 2.7 9.8e-38 128.5 2.7 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KXL46453.1 - 2.2e-07 30.6 2.7 4.7e-07 29.5 2.7 1.6 1 0 0 1 1 1 1 KOW motif DUF1223 PF06764.11 KXL46453.1 - 0.025 14.6 0.1 0.028 14.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) DUF3135 PF11333.8 KXL46454.1 - 1.3 9.3 8.2 5.7 7.3 0.2 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3135) Ost4 PF10215.9 KXL46455.1 - 9.9e-18 63.7 2.4 1.3e-17 63.3 2.4 1.2 1 0 0 1 1 1 1 Oligosaccaryltransferase SVA PF05326.11 KXL46455.1 - 0.066 13.2 0.0 0.074 13.0 0.0 1.1 1 0 0 1 1 1 0 Seminal vesicle autoantigen (SVA) DFRP_C PF16543.5 KXL46456.1 - 5.6e-26 90.9 4.2 5.6e-26 90.9 4.2 3.0 3 0 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 KXL46456.1 - 1.4e-06 28.1 1.9 1.4e-06 28.1 1.9 2.7 3 1 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KXL46456.1 - 7.2e-06 25.7 9.9 7.2e-05 22.5 1.7 3.3 3 0 0 3 3 3 1 CCCH-type zinc finger Torus PF16131.5 KXL46456.1 - 1.2e-05 25.9 14.1 2.5e-05 24.9 3.8 3.3 3 2 0 3 3 3 2 Torus domain zf_CCCH_4 PF18345.1 KXL46456.1 - 0.00026 20.9 7.5 0.00026 20.9 7.5 3.3 4 0 0 4 4 4 1 Zinc finger domain zf-CCCH_3 PF15663.5 KXL46456.1 - 0.0035 17.5 0.7 0.51 10.6 0.2 2.7 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KXL46456.1 - 0.0088 16.5 13.7 0.023 15.2 4.1 2.9 2 1 0 2 2 2 1 RNA-binding, Nab2-type zinc finger DUF4078 PF13300.6 KXL46456.1 - 0.072 13.4 0.6 0.072 13.4 0.6 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4078) DUF866 PF05907.13 KXL46457.1 - 7.7e-69 230.5 0.2 8.7e-69 230.4 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) PHD PF00628.29 KXL46457.1 - 0.037 13.9 0.9 0.065 13.1 0.9 1.4 1 0 0 1 1 1 0 PHD-finger Rubredoxin_2 PF18073.1 KXL46457.1 - 0.31 10.8 5.4 1.5 8.6 0.4 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain Zn_ribbon_SprT PF17283.2 KXL46457.1 - 0.38 10.7 6.3 2.1 8.3 6.3 2.0 1 1 0 1 1 1 0 SprT-like zinc ribbon domain Rubredoxin PF00301.20 KXL46457.1 - 2.4 8.3 0.0 2.4 8.3 0.0 3.5 4 0 0 4 4 4 0 Rubredoxin adh_short PF00106.25 KXL46459.1 - 2.3e-24 86.0 0.1 3.6e-24 85.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL46459.1 - 4.9e-22 78.6 0.1 6.2e-22 78.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL46459.1 - 4.5e-08 33.2 0.1 1.1e-07 32.0 0.1 1.7 1 1 0 1 1 1 1 KR domain AA_permease_2 PF13520.6 KXL46460.1 - 1.7e-30 106.2 31.6 2.1e-30 105.9 31.6 1.0 1 0 0 1 1 1 1 Amino acid permease AAA_6 PF12774.7 KXL46461.1 - 2.4e-124 414.6 0.0 3.5e-123 410.7 0.0 2.8 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KXL46461.1 - 4.7e-118 394.8 5.1 4.7e-118 394.8 5.1 4.7 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 KXL46461.1 - 3.7e-109 365.9 1.9 3.7e-109 365.9 1.9 4.8 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 1 AAA_9 PF12781.7 KXL46461.1 - 2e-74 249.5 0.6 2e-74 249.5 0.6 4.9 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 KXL46461.1 - 3.1e-68 229.9 0.1 1.6e-67 227.6 0.0 2.4 3 0 0 3 3 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 KXL46461.1 - 8.5e-44 149.2 0.0 1.7e-37 128.7 0.0 4.6 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 KXL46461.1 - 2.8e-39 135.1 6.8 6e-39 134.0 6.8 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 KXL46461.1 - 1.5e-29 102.8 0.2 3.8e-12 46.4 0.0 6.4 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_lid_11 PF18198.1 KXL46461.1 - 5.5e-29 101.1 0.0 2e-28 99.3 0.0 2.0 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KXL46461.1 - 4.3e-28 97.8 0.1 2.6e-25 88.8 0.0 3.5 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 KXL46461.1 - 4.1e-20 72.2 3.7 6e-17 61.9 0.0 4.7 4 0 0 4 4 4 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 KXL46461.1 - 2.9e-17 63.2 0.4 0.0074 16.6 0.0 7.2 6 0 0 6 6 5 4 AAA domain AAA PF00004.29 KXL46461.1 - 2.3e-14 53.9 0.0 0.0023 18.3 0.0 5.3 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KXL46461.1 - 9.5e-10 39.1 0.0 0.11 13.0 0.0 5.6 4 0 0 4 4 4 2 AAA domain T2SSE PF00437.20 KXL46461.1 - 8.5e-09 34.9 0.0 0.0099 15.0 0.0 3.9 3 0 0 3 3 3 3 Type II/IV secretion system protein AAA_33 PF13671.6 KXL46461.1 - 1.6e-08 34.8 2.0 0.44 10.7 0.0 5.5 5 0 0 5 5 4 2 AAA domain AAA_16 PF13191.6 KXL46461.1 - 5e-08 33.5 9.6 1.8 9.0 0.0 8.7 9 0 0 9 9 6 1 AAA ATPase domain Mg_chelatase PF01078.21 KXL46461.1 - 1.2e-05 24.8 0.9 0.58 9.5 0.0 4.0 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.18 KXL46461.1 - 4.1e-05 23.0 0.2 3.4 7.0 0.0 4.4 4 0 0 4 4 3 1 FtsK/SpoIIIE family AAA_19 PF13245.6 KXL46461.1 - 0.0001 22.6 0.8 0.24 11.7 0.0 4.7 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.6 KXL46461.1 - 0.00017 21.3 0.2 25 4.5 0.0 4.6 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.27 KXL46461.1 - 0.00018 22.0 0.0 6.4 7.3 0.0 4.9 3 0 0 3 3 3 0 ABC transporter AAA_24 PF13479.6 KXL46461.1 - 0.00019 21.3 0.7 6.3 6.5 0.0 4.6 4 0 0 4 4 4 0 AAA domain AAA_lid_1 PF17857.1 KXL46461.1 - 0.0002 21.5 0.2 0.0033 17.6 0.0 3.0 3 0 0 3 3 2 1 AAA+ lid domain AAA_29 PF13555.6 KXL46461.1 - 0.00031 20.4 0.1 2.2 8.1 0.0 3.6 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KXL46461.1 - 0.00037 20.1 2.7 0.85 9.2 0.0 5.7 6 1 0 6 6 4 1 AAA domain IstB_IS21 PF01695.17 KXL46461.1 - 0.0016 18.2 2.2 1.1 8.9 0.0 5.0 6 0 0 6 6 4 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KXL46461.1 - 0.0062 16.9 0.1 18 5.8 0.0 4.6 4 0 0 4 4 4 0 RNA helicase Rad17 PF03215.15 KXL46461.1 - 0.013 15.4 2.0 5.6 6.8 0.0 5.2 6 0 0 6 6 5 0 Rad17 P-loop domain Spuma_A9PTase PF03539.14 KXL46461.1 - 0.057 13.6 0.1 3.3 7.8 0.0 3.3 3 0 0 3 3 3 0 Spumavirus aspartic protease (A9) P53_tetramer PF07710.11 KXL46461.1 - 0.12 11.7 0.2 0.54 9.6 0.0 2.2 2 0 0 2 2 1 0 P53 tetramerisation motif PduV-EutP PF10662.9 KXL46461.1 - 0.55 10.0 1.9 12 5.7 0.0 4.0 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation Flagellin_C PF00700.21 KXL46461.1 - 1.5 9.3 5.8 12 6.4 0.1 4.1 3 0 0 3 3 2 0 Bacterial flagellin C-terminal helical region DUF4482 PF14818.6 KXL46461.1 - 1.8 9.5 15.2 0.65 10.9 0.2 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) NACHT PF05729.12 KXL46461.1 - 2.6 8.0 9.8 32 4.4 0.1 5.3 6 0 0 6 6 4 0 NACHT domain RPW8 PF05659.11 KXL46461.1 - 4.3 7.0 11.4 20 4.8 0.3 4.3 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Acetyltransf_1 PF00583.25 KXL46462.1 - 4.9e-09 36.5 0.1 1.1e-08 35.4 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Pho86 PF11124.8 KXL46462.1 - 0.00027 20.5 0.5 0.012 15.1 0.2 2.1 2 0 0 2 2 2 1 Inorganic phosphate transporter Pho86 Acetyltransf_10 PF13673.7 KXL46462.1 - 0.001 19.0 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXL46462.1 - 0.0048 17.3 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 KXL46462.1 - 0.014 15.1 0.1 0.03 14.0 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 KXL46462.1 - 0.028 14.5 0.3 0.069 13.3 0.1 1.7 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KXL46462.1 - 0.041 14.0 0.1 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF554 PF04474.12 KXL46462.1 - 0.13 11.7 0.3 0.2 11.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF554) Pkinase PF00069.25 KXL46463.1 - 1.8e-47 161.9 0.0 5.3e-47 160.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL46463.1 - 5e-20 71.9 0.0 1.2e-19 70.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXL46463.1 - 0.016 14.2 0.1 0.029 13.3 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KXL46463.1 - 0.02 14.8 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Phage_TTP_12 PF16461.5 KXL46463.1 - 0.024 14.3 0.0 0.069 12.8 0.0 1.7 2 0 0 2 2 2 0 Lambda phage tail tube protein, TTP FTA2 PF13095.6 KXL46463.1 - 0.094 12.3 0.0 14 5.3 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KXL46463.1 - 0.095 12.0 0.0 0.25 10.6 0.0 1.6 2 0 0 2 2 2 0 Kinase-like SNARE PF05739.19 KXL46464.1 - 8.7e-10 38.5 1.2 1.3e-09 37.9 0.2 1.9 2 0 0 2 2 2 1 SNARE domain Use1 PF09753.9 KXL46464.1 - 5.4e-09 36.2 0.0 7.1e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 TetR_C_18 PF17923.1 KXL46464.1 - 0.086 13.4 0.1 0.16 12.5 0.1 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF4407 PF14362.6 KXL46464.1 - 0.25 10.7 6.7 7 5.9 6.6 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4559 PF15112.6 KXL46464.1 - 1.1 8.8 5.8 2.9 7.5 1.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) zf-TRAF PF02176.18 KXL46465.1 - 8.9e-11 42.3 22.1 2.7e-05 24.8 4.2 3.8 1 1 2 3 3 3 3 TRAF-type zinc finger zf-RING_2 PF13639.6 KXL46465.1 - 6.8e-07 29.5 14.0 6.8e-07 29.5 14.0 3.7 3 1 1 4 4 3 1 Ring finger domain zf-C3HC4 PF00097.25 KXL46465.1 - 8.1e-07 28.8 11.7 8.1e-07 28.8 11.7 3.7 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXL46465.1 - 1.1e-05 25.2 11.6 1.1e-05 25.2 11.6 3.2 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXL46465.1 - 2.3e-05 24.3 13.7 2.3e-05 24.3 13.7 3.0 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXL46465.1 - 6.2e-05 22.8 15.2 6.2e-05 22.8 15.2 4.0 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXL46465.1 - 0.00021 21.1 10.5 0.00021 21.1 10.5 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF_2 PF15965.5 KXL46465.1 - 0.0028 18.1 9.8 0.0028 18.1 9.8 3.7 1 1 3 4 4 4 1 TRAF-like zinc-finger zf-Nse PF11789.8 KXL46465.1 - 0.011 15.6 4.9 0.011 15.6 4.9 2.9 4 0 0 4 4 4 0 Zinc-finger of the MIZ type in Nse subunit Snapin_Pallidin PF14712.6 KXL46465.1 - 0.015 15.7 2.1 0.12 12.8 0.1 2.4 2 1 0 2 2 2 0 Snapin/Pallidin zf-RING_6 PF14835.6 KXL46465.1 - 0.022 14.6 9.2 0.022 14.6 9.2 3.1 2 2 0 2 2 2 0 zf-RING of BARD1-type protein Sina PF03145.16 KXL46465.1 - 2.1 8.2 18.6 0.96 9.4 3.8 2.9 1 1 2 3 3 3 0 Seven in absentia protein family MbeD_MobD PF04899.12 KXL46465.1 - 6 7.1 9.4 0.78 9.9 4.1 2.2 2 0 0 2 2 2 0 MbeD/MobD like ADH_N PF08240.12 KXL46467.1 - 8.2e-30 102.9 0.8 1.4e-29 102.1 0.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXL46467.1 - 2.9e-20 72.5 0.1 5.6e-20 71.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXL46467.1 - 0.0003 21.9 0.0 0.00055 21.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KXL46467.1 - 0.0064 16.0 0.3 0.014 14.8 0.3 1.7 1 0 0 1 1 1 1 short chain dehydrogenase 2-Hacid_dh_C PF02826.19 KXL46467.1 - 0.018 14.4 0.1 0.036 13.4 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Asp PF00026.23 KXL46468.1 - 2.4e-77 260.4 15.3 2.8e-77 260.2 15.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXL46468.1 - 1.1e-10 42.1 7.4 4.7e-07 30.2 0.0 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KXL46468.1 - 1.4e-05 25.6 2.8 0.052 14.2 0.8 2.9 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KXL46468.1 - 0.004 16.9 0.0 0.011 15.5 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal GPI-anchored PF10342.9 KXL46468.1 - 0.78 10.5 5.1 1.5 9.6 0.5 3.1 2 1 2 4 4 4 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family HET PF06985.11 KXL46469.1 - 1.9e-26 93.2 1.5 2.6e-26 92.7 0.0 2.0 3 0 0 3 3 3 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 KXL46471.1 - 3.5e-32 111.7 37.7 6.9e-32 110.7 29.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXL46471.1 - 6.2e-09 34.8 2.3 6.2e-09 34.8 2.3 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1206 PF06724.11 KXL46471.1 - 0.36 11.0 4.6 0.42 10.7 0.2 3.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) LRR_4 PF12799.7 KXL46472.1 - 2.1e-31 107.5 28.1 9.8e-07 29.0 1.3 6.5 2 2 5 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXL46472.1 - 6.7e-21 73.8 27.0 7.1e-06 25.7 5.0 6.0 2 1 5 7 7 7 6 Leucine rich repeat LRR_9 PF14580.6 KXL46472.1 - 1.2e-13 50.9 13.9 1.1e-08 34.8 3.7 3.4 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 KXL46472.1 - 0.016 15.2 19.4 4.2 7.7 0.1 7.6 8 0 0 8 8 8 0 Leucine Rich repeat LRR_1 PF00560.33 KXL46472.1 - 1.6 9.6 29.3 23 6.1 2.3 8.8 7 3 0 7 7 7 0 Leucine Rich Repeat TauD PF02668.16 KXL46473.1 - 2.1e-51 175.3 0.3 2.4e-51 175.1 0.3 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TPR_1 PF00515.28 KXL46475.1 - 0.0076 16.0 0.4 0.035 13.9 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Asp_Glu_race PF01177.22 KXL46475.1 - 0.087 12.7 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase NOC3p PF07540.11 KXL46476.1 - 1.1e-28 99.5 3.3 2.6e-28 98.3 0.1 2.8 2 1 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.17 KXL46476.1 - 1.2e-25 90.5 0.1 1.2e-25 90.5 0.1 2.3 2 1 0 2 2 2 1 CBF/Mak21 family LPD3 PF18798.1 KXL46476.1 - 1.2 9.4 5.5 6.4 7.1 0.0 3.1 3 1 0 3 3 3 0 Large polyvalent protein-associated domain 3 UPF0113 PF03657.13 KXL46477.1 - 4.6e-27 94.1 0.0 5.9e-26 90.5 0.0 2.1 2 0 0 2 2 2 1 UPF0113 PUA domain UPF0113_N PF17833.1 KXL46477.1 - 5.6e-27 94.1 0.0 7.5e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain Sortase PF04203.13 KXL46477.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Sortase domain adh_short PF00106.25 KXL46478.1 - 1.5e-24 86.6 0.1 1.8e-24 86.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL46478.1 - 1.4e-17 64.0 0.0 1.7e-17 63.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL46478.1 - 2.3e-05 24.4 0.0 2.7e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 KR domain bVLRF1 PF18826.1 KXL46479.1 - 4.2e-62 208.4 0.1 7.7e-62 207.6 0.1 1.4 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 KXL46479.1 - 2.5e-06 27.7 0.0 5.9e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KXL46479.1 - 0.00033 21.0 0.3 0.00073 19.9 0.3 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 KXL46479.1 - 0.011 16.3 0.0 0.023 15.3 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXL46479.1 - 0.11 13.2 0.0 0.24 12.0 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXL46479.1 - 0.12 12.9 0.0 0.38 11.5 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeat Zip PF02535.22 KXL46480.1 - 4.9e-28 98.3 4.0 9.6e-28 97.4 4.0 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter DUF4523 PF15023.6 KXL46480.1 - 0.019 14.8 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) PHO4 PF01384.20 KXL46480.1 - 0.046 12.8 5.4 0.24 10.4 4.4 2.2 2 0 0 2 2 2 0 Phosphate transporter family DctQ PF04290.12 KXL46480.1 - 0.13 12.2 4.3 0.05 13.5 0.8 2.0 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Voltage_CLC PF00654.20 KXL46481.1 - 6.3e-90 302.0 23.2 6.3e-90 302.0 23.2 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel MAPEG PF01124.18 KXL46483.1 - 2e-24 85.9 1.5 2.4e-24 85.7 1.5 1.1 1 0 0 1 1 1 1 MAPEG family VASt PF16016.5 KXL46484.1 - 6.9e-34 117.5 0.0 1.1e-33 116.8 0.0 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KXL46484.1 - 4.3e-23 81.4 0.2 2.2e-22 79.1 0.0 2.3 2 0 0 2 2 2 1 GRAM domain Iwr1 PF08574.10 KXL46485.1 - 3.6e-15 56.7 6.2 3.6e-15 56.7 6.2 2.2 2 0 0 2 2 2 1 Transcription factor Iwr1 Aa_trans PF01490.18 KXL46487.1 - 7.5e-36 123.7 19.4 1.3e-35 122.9 19.4 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Transp_cyt_pur PF02133.15 KXL46488.1 - 8.6e-16 57.7 38.8 1.3e-15 57.1 38.8 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin AMP-binding PF00501.28 KXL46489.1 - 5.3e-52 176.8 0.1 7.3e-52 176.4 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme B56 PF01603.20 KXL46489.1 - 0.19 10.7 0.0 0.27 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) TFIIS_M PF07500.14 KXL46490.1 - 2.6e-28 98.7 0.7 5e-28 97.8 0.7 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KXL46490.1 - 1.2e-17 63.5 9.1 2e-17 62.7 9.1 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KXL46490.1 - 2.2e-14 53.2 0.4 4.7e-14 52.1 0.4 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain RRF PF01765.19 KXL46491.1 - 3.5e-32 111.6 0.0 4.8e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Ribosome recycling factor AMP-binding PF00501.28 KXL46492.1 - 4.1e-35 121.2 0.0 5e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXL46492.1 - 2.6e-15 57.1 0.1 4.6e-15 56.4 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.18 KXL46493.1 - 9.5e-24 83.8 0.2 1.4e-23 83.3 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL46493.1 - 0.013 15.6 12.0 0.031 14.4 12.0 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain ROQ_II PF18386.1 KXL46493.1 - 0.15 12.0 0.1 4.4 7.2 0.0 2.4 2 0 0 2 2 2 0 Roquin II domain RNase_P_p30 PF01876.16 KXL46494.1 - 5.3e-61 205.8 0.0 7.1e-61 205.4 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 MRP_L53 PF10780.9 KXL46495.1 - 4.5e-16 58.8 0.1 6.5e-16 58.2 0.1 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 QIL1 PF15884.5 KXL46496.1 - 0.043 14.4 0.0 0.09 13.4 0.0 1.6 1 0 0 1 1 1 0 MICOS complex subunit MIC13, QIL1 zf-primase PF09329.11 KXL46497.1 - 0.1 12.4 0.5 0.2 11.5 0.5 1.5 1 0 0 1 1 1 0 Primase zinc finger Pro_CA PF00484.19 KXL46498.1 - 3.2e-08 34.0 0.0 6.1e-08 33.1 0.0 1.5 1 1 0 1 1 1 1 Carbonic anhydrase DUF3807 PF12720.7 KXL46499.1 - 1.1e-24 87.7 1.4 1.5e-24 87.2 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) DUF1295 PF06966.12 KXL46500.1 - 1.1e-53 182.2 0.4 1.7e-53 181.6 0.4 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KXL46500.1 - 2.7e-05 24.5 1.4 4.7e-05 23.7 0.1 2.2 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 KXL46500.1 - 3.7e-05 23.8 1.9 0.00048 20.1 0.0 3.0 2 1 2 4 4 4 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 KXL46500.1 - 0.0081 16.5 0.0 0.2 12.1 0.0 2.6 1 1 1 2 2 2 1 Phospholipid methyltransferase OGG_N PF07934.12 KXL46501.1 - 1.1e-33 115.9 0.0 1.8e-33 115.2 0.0 1.3 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 KXL46501.1 - 6.7e-17 61.9 0.0 1.2e-16 61.1 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KXL46501.1 - 0.0031 17.3 0.0 0.0081 16.0 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Glyco_hydro_125 PF06824.11 KXL46502.1 - 5.5e-178 592.1 0.4 6.3e-178 591.9 0.4 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) DASH_Dam1 PF08653.10 KXL46502.1 - 0.043 13.6 0.7 0.17 11.7 0.2 2.3 2 0 0 2 2 2 0 DASH complex subunit Dam1 RTC4 PF14474.6 KXL46503.1 - 1.6e-25 89.6 0.0 1.7e-25 89.5 0.0 1.0 1 0 0 1 1 1 1 RTC4-like domain COPIIcoated_ERV PF07970.12 KXL46504.1 - 1.8e-67 227.4 0.1 2.4e-67 227.0 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KXL46504.1 - 7.2e-30 103.2 0.0 1.1e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Sec20 PF03908.13 KXL46505.1 - 5.4e-15 55.1 0.3 5.4e-15 55.1 0.3 3.0 3 0 0 3 3 3 1 Sec20 DUF1664 PF07889.12 KXL46505.1 - 0.085 12.9 4.7 0.14 12.2 1.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin_2 PF14523.6 KXL46505.1 - 6.7 7.1 9.1 5.3 7.5 3.8 2.9 2 1 0 2 2 2 0 Syntaxin-like protein CFEM PF05730.11 KXL46506.1 - 0.0019 18.2 7.3 0.0057 16.7 7.3 1.8 1 1 0 1 1 1 1 CFEM domain Methyltransf_28 PF02636.17 KXL46507.1 - 4.2e-37 128.2 0.0 8.1e-37 127.3 0.0 1.4 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 KXL46507.1 - 0.035 14.0 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase PALP PF00291.25 KXL46508.1 - 1.4e-64 218.4 1.2 1.7e-64 218.1 1.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SF3b1 PF08920.10 KXL46509.1 - 7.8e-24 84.5 0.7 7.8e-24 84.5 0.7 2.1 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 KXL46509.1 - 1.4e-12 47.8 3.9 0.2 12.1 0.1 7.8 6 1 3 9 9 9 5 HEAT repeats HEAT PF02985.22 KXL46509.1 - 2.3e-10 39.8 6.2 0.13 12.6 0.1 9.0 10 0 0 10 10 10 2 HEAT repeat Cnd1 PF12717.7 KXL46509.1 - 1.9e-08 34.5 0.6 1.2 9.2 0.0 6.4 5 2 2 7 7 7 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KXL46509.1 - 2.1e-07 31.3 4.2 0.14 12.7 0.0 6.6 6 1 1 7 7 7 2 HEAT-like repeat NUC173 PF08161.12 KXL46509.1 - 0.0013 18.4 0.3 1.2 8.8 0.0 4.5 4 1 1 5 5 5 1 NUC173 domain Vac14_Fab1_bd PF12755.7 KXL46509.1 - 0.0025 18.4 0.1 96 3.7 0.0 5.4 6 0 0 6 6 6 0 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KXL46509.1 - 0.0036 16.9 0.2 0.92 9.0 0.0 3.3 3 0 0 3 3 3 1 CLASP N terminal zf-ISL3 PF14690.6 KXL46510.1 - 0.96 10.2 6.3 3.6 8.3 0.1 2.3 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 dUTPase PF00692.19 KXL46511.1 - 2.6e-40 137.1 0.0 3.3e-40 136.8 0.0 1.1 1 0 0 1 1 1 1 dUTPase Lactamase_B PF00753.27 KXL46512.1 - 2.1e-06 27.9 0.3 3.2e-06 27.3 0.3 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily NuA4 PF09340.10 KXL46513.1 - 1.4e-27 95.4 1.1 1.7e-27 95.1 0.0 1.6 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 DUF349 PF03993.12 KXL46513.1 - 0.071 13.4 0.2 0.12 12.7 0.2 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) GNAT_acetyltr_2 PF13718.6 KXL46514.1 - 1.3e-97 325.7 0.0 3.2e-97 324.4 0.0 1.7 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KXL46514.1 - 2e-76 256.8 0.6 4.1e-76 255.8 0.6 1.5 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 KXL46514.1 - 2.2e-66 223.1 0.0 5.3e-65 218.6 0.0 2.8 3 0 0 3 3 3 1 Helicase DUF1726 PF08351.11 KXL46514.1 - 3.5e-33 113.4 0.0 1.1e-32 111.8 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 KXL46514.1 - 0.00014 21.7 0.1 0.057 13.1 0.0 3.4 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.6 KXL46514.1 - 0.0038 17.5 0.0 0.31 11.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain DUF815 PF05673.13 KXL46514.1 - 0.036 13.2 0.1 0.13 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Acetyltransf_1 PF00583.25 KXL46514.1 - 0.083 13.1 0.0 0.65 10.2 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family AAA_19 PF13245.6 KXL46514.1 - 0.088 13.1 0.0 0.36 11.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain Acetyltransf_7 PF13508.7 KXL46514.1 - 0.12 12.8 0.0 0.45 11.0 0.0 2.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_transf_90 PF05686.12 KXL46515.1 - 3.3e-14 52.6 0.0 2e-06 27.0 0.0 3.2 3 0 0 3 3 3 3 Glycosyl transferase family 90 NPL4 PF05021.15 KXL46516.1 - 2.4e-128 427.9 0.0 2.9e-128 427.6 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 KXL46516.1 - 1.2e-70 236.3 0.1 1.6e-70 235.8 0.1 1.2 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 KXL46516.1 - 0.017 15.6 0.0 0.055 14.0 0.0 1.9 1 1 0 1 1 1 0 Nuclear pore localisation protein NPL4 Sec66 PF09802.9 KXL46517.1 - 3.4e-76 254.8 0.4 4.1e-76 254.6 0.4 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF3848 PF12959.7 KXL46517.1 - 0.07 13.2 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) F-box-like PF12937.7 KXL46519.1 - 0.0056 16.5 0.0 0.045 13.6 0.0 2.6 1 1 0 1 1 1 1 F-box-like DUF3844 PF12955.7 KXL46520.1 - 3.3e-32 110.8 1.5 4.8e-32 110.2 1.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) ChaC PF04752.12 KXL46522.1 - 5.1e-52 176.5 0.0 6.8e-52 176.1 0.0 1.2 1 0 0 1 1 1 1 ChaC-like protein PP2C_2 PF13672.6 KXL46523.1 - 0.00071 19.3 0.1 0.00099 18.8 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KXL46523.1 - 0.0018 18.3 0.1 0.0043 17.0 0.1 1.8 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Ctr PF04145.15 KXL46524.1 - 4e-32 111.9 0.3 5.1e-32 111.5 0.3 1.1 1 0 0 1 1 1 1 Ctr copper transporter family ORC3_N PF07034.11 KXL46525.1 - 2e-28 99.5 0.7 1.2e-26 93.6 0.7 2.3 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 KXL46525.1 - 9.8e-28 97.0 0.8 9.1e-17 61.4 0.0 2.5 1 1 1 2 2 2 2 Origin recognition complex winged helix C-terminal Sel1 PF08238.12 KXL46526.1 - 8.4e-13 48.5 9.8 0.00031 21.3 1.8 3.9 3 0 0 3 3 3 3 Sel1 repeat RabGAP-TBC PF00566.18 KXL46529.1 - 1.7e-34 119.3 0.0 7.2e-27 94.4 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain ArfA PF03889.13 KXL46529.1 - 0.23 11.0 0.0 0.5 9.9 0.0 1.5 1 0 0 1 1 1 0 Alternative ribosome-rescue factor A Sulfate_transp PF00916.20 KXL46531.1 - 1.7e-109 366.1 19.2 2.3e-109 365.6 19.2 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KXL46531.1 - 5.9e-08 32.4 0.0 1.1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KXL46531.1 - 0.0091 16.4 4.3 0.0091 16.4 4.3 3.0 2 1 0 2 2 2 2 Molybdate transporter of MFS superfamily RPEL PF02755.15 KXL46532.1 - 1.4 8.8 4.5 24 4.8 0.0 2.3 2 0 0 2 2 2 0 RPEL repeat PWWP PF00855.17 KXL46534.1 - 1e-17 64.3 0.0 1e-17 64.3 0.0 3.1 2 1 1 3 3 3 1 PWWP domain Med26 PF08711.11 KXL46534.1 - 0.032 14.3 0.2 0.24 11.4 0.2 2.4 2 0 0 2 2 2 0 TFIIS helical bundle-like domain Pyr_redox_2 PF07992.14 KXL46535.1 - 3.1e-39 135.0 0.1 4.8e-39 134.4 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXL46535.1 - 1.9e-19 70.0 0.1 8.6e-19 67.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KXL46535.1 - 3.2e-16 59.6 0.4 8e-16 58.3 0.0 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Rhodanese PF00581.20 KXL46535.1 - 1.1e-14 54.8 0.0 5.3e-14 52.6 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain Pyr_redox_3 PF13738.6 KXL46535.1 - 6.2e-08 32.2 0.0 9.2e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXL46535.1 - 2.3e-07 30.3 0.1 2.3e-06 27.0 0.1 2.5 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KXL46535.1 - 3e-07 30.4 1.8 0.011 15.3 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXL46535.1 - 8e-07 28.4 0.8 0.0015 17.7 0.0 2.2 1 1 1 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.14 KXL46535.1 - 4.9e-06 25.5 0.5 0.0089 14.8 0.0 2.2 1 1 1 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.6 KXL46535.1 - 6.5e-05 23.0 1.2 0.093 12.7 0.0 2.3 1 1 1 2 2 2 2 FAD-NAD(P)-binding Amino_oxidase PF01593.24 KXL46535.1 - 0.00015 21.2 0.2 0.00097 18.5 0.2 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase GIDA PF01134.22 KXL46535.1 - 0.00068 18.8 1.1 0.08 12.0 0.4 2.7 2 1 1 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KXL46535.1 - 0.0023 17.3 0.1 0.0037 16.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXL46535.1 - 0.0034 17.6 0.0 0.0097 16.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 KXL46535.1 - 0.018 14.9 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 KXL46535.1 - 0.029 13.7 0.4 5.1 6.3 0.0 2.1 1 1 1 2 2 2 0 FAD dependent oxidoreductase Spuma_A9PTase PF03539.14 KXL46535.1 - 0.03 14.5 0.0 0.051 13.7 0.0 1.3 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) 2-Hacid_dh_C PF02826.19 KXL46535.1 - 0.055 12.8 0.0 0.16 11.3 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KXL46535.1 - 0.13 12.7 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ThiF PF00899.21 KXL46535.1 - 0.14 11.5 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 ThiF family CENP-T_N PF16171.5 KXL46535.1 - 0.19 10.6 0.0 0.47 9.3 0.0 1.5 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T N-terminus Lactonase PF10282.9 KXL46537.1 - 1.7e-27 96.6 0.0 4.9e-27 95.1 0.0 1.7 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Cofilin_ADF PF00241.20 KXL46538.1 - 2e-25 88.9 0.0 3e-12 46.4 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Pkinase PF00069.25 KXL46539.1 - 1.9e-73 247.1 0.0 2.4e-73 246.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL46539.1 - 1.5e-38 132.5 0.0 2.1e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXL46539.1 - 0.00017 21.0 0.0 0.00035 20.0 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Rad21_Rec8 PF04824.16 KXL46539.1 - 0.13 11.6 0.3 0.3 10.4 0.3 1.6 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein PRCC PF10253.9 KXL46539.1 - 0.23 12.3 5.4 0.32 11.8 5.4 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Tmemb_170 PF10190.9 KXL46541.1 - 2.1e-22 79.5 10.3 2.4e-22 79.3 10.3 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 Phage_holin_3_6 PF07332.11 KXL46541.1 - 0.8 9.8 5.9 0.38 10.8 3.8 1.5 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Pectate_lyase_3 PF12708.7 KXL46543.1 - 5.4e-97 323.8 12.0 3.3e-83 278.8 4.5 2.7 2 1 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KXL46543.1 - 5.5e-06 26.0 1.2 0.017 14.8 0.1 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase DNA_binding_1 PF01035.20 KXL46544.1 - 7.4e-29 99.7 0.0 9e-29 99.4 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain EBP PF05241.12 KXL46545.1 - 8.7e-72 240.3 9.6 1e-71 240.1 9.6 1.0 1 0 0 1 1 1 1 Emopamil binding protein Methyltransf_11 PF08241.12 KXL46546.1 - 1.3e-10 41.8 0.0 2.9e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXL46546.1 - 1.7e-10 41.0 0.0 3.1e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL46546.1 - 3e-07 31.1 0.0 7e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL46546.1 - 1.4e-06 28.9 0.0 3.3e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL46546.1 - 0.0012 18.6 0.0 0.0028 17.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXL46546.1 - 0.0063 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family GhoS PF11080.8 KXL46546.1 - 0.1 12.6 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 Endoribonuclease GhoS NmrA PF05368.13 KXL46547.1 - 1.9e-50 171.6 0.1 2.4e-50 171.3 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXL46547.1 - 3.1e-11 43.5 0.1 5.5e-11 42.7 0.0 1.4 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXL46547.1 - 0.0015 17.6 0.0 0.0021 17.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DXP_reductoisom PF02670.16 KXL46547.1 - 0.0047 17.6 0.6 0.016 16.0 0.1 2.1 3 0 0 3 3 3 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Adaptin_N PF01602.20 KXL46548.1 - 4.8e-142 474.2 0.2 5.8e-142 473.9 0.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KXL46548.1 - 3e-21 75.8 1.7 3.7e-21 75.5 0.1 2.0 2 0 0 2 2 2 1 Adaptin C-terminal domain Cnd1 PF12717.7 KXL46548.1 - 3.5e-07 30.4 6.1 0.00042 20.4 0.0 4.1 2 2 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXL46548.1 - 1.5e-06 28.5 2.3 0.45 10.9 0.0 5.3 4 1 1 5 5 5 2 HEAT repeats DUF3730 PF12530.8 KXL46548.1 - 0.00068 19.3 0.3 0.016 14.8 0.1 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF3730) HEAT PF02985.22 KXL46548.1 - 0.00085 19.4 0.7 11 6.6 0.0 4.3 3 0 0 3 3 3 2 HEAT repeat RICTOR_M PF14666.6 KXL46548.1 - 0.043 13.6 0.0 0.13 12.0 0.0 1.9 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain Rad51 PF08423.11 KXL46549.1 - 1.7e-08 34.1 0.0 9.3e-06 25.1 0.0 2.2 2 0 0 2 2 2 2 Rad51 DUF3128 PF11326.8 KXL46550.1 - 0.002 18.5 0.4 0.0077 16.6 0.4 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) Ndufs5 PF10200.9 KXL46550.1 - 0.0041 17.4 0.0 0.0061 16.8 0.0 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa COX6B PF02297.17 KXL46550.1 - 0.08 13.2 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb DUF1793 PF08760.11 KXL46551.1 - 2.1e-67 226.8 0.2 4.6e-67 225.6 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 KXL46551.1 - 4.2e-62 208.9 0.4 4.6e-48 163.2 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4965) DUF5127 PF17168.4 KXL46551.1 - 1.4e-38 133.0 0.2 2e-37 129.2 0.2 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 KXL46551.1 - 0.0086 15.6 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) SnoaL_3 PF13474.6 KXL46551.1 - 0.022 15.0 0.1 3.6 7.9 0.0 2.5 2 0 0 2 2 2 0 SnoaL-like domain Tiam_CC_Ex PF18385.1 KXL46551.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 T-lymphoma invasion and metastasis CC-Ex domain Ank_2 PF12796.7 KXL46552.1 - 1.4e-16 60.9 0.0 1.8e-13 50.8 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXL46552.1 - 1e-15 57.9 0.2 3e-08 34.1 0.0 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXL46552.1 - 1.2e-10 41.4 0.5 8.1e-07 29.2 0.1 3.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXL46552.1 - 1e-08 34.7 0.0 0.001 19.3 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KXL46552.1 - 8.2e-07 29.2 0.1 0.0069 16.8 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeat NAM-associated PF14303.6 KXL46552.1 - 0.0012 19.6 39.1 2.9 8.6 0.0 6.4 3 2 0 4 4 4 1 No apical meristem-associated C-terminal domain Ribosomal_S7e PF01251.18 KXL46553.1 - 1.4e-80 269.4 0.1 1.7e-80 269.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Pkinase PF00069.25 KXL46554.1 - 5.2e-56 189.9 0.0 7.3e-56 189.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL46554.1 - 7.2e-19 68.1 0.0 1.1e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXL46554.1 - 1.8e-07 30.8 0.0 1.3e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KXL46554.1 - 0.00012 22.1 0.9 0.14 12.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXL46554.1 - 0.00033 19.6 0.0 0.0012 17.7 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 KXL46554.1 - 0.032 13.8 0.0 0.079 12.5 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 KXL46554.1 - 0.037 13.0 0.0 0.059 12.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FAD_binding_7 PF03441.14 KXL46555.1 - 1.3e-74 250.1 0.2 2.1e-74 249.4 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KXL46555.1 - 7.9e-35 120.3 0.0 1.3e-34 119.6 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase DUF2149 PF09919.9 KXL46555.1 - 0.23 11.8 0.0 0.49 10.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) SF1-HH PF16275.5 KXL46557.1 - 5.3e-42 142.7 0.1 5.3e-42 142.7 0.1 1.9 1 1 1 2 2 2 1 Splicing factor 1 helix-hairpin domain ADH_N PF08240.12 KXL46558.1 - 0.099 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Methyltransf_16 PF10294.9 KXL46560.1 - 2.2e-11 43.8 0.0 3.2e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KXL46560.1 - 0.083 12.3 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Abhydrolase_1 PF00561.20 KXL46562.1 - 5e-19 68.9 0.0 7.9e-18 65.0 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXL46562.1 - 2.5e-13 51.1 11.1 2.5e-13 51.1 11.1 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXL46562.1 - 7.9e-12 44.9 0.0 1.2e-10 41.0 0.0 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 KXL46562.1 - 2.6e-05 24.0 0.0 6.8e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.11 KXL46562.1 - 0.00021 20.7 0.0 0.00054 19.4 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.20 KXL46562.1 - 0.02 15.0 0.0 0.21 11.7 0.0 2.4 1 1 0 1 1 1 0 Thioesterase domain Spo7 PF03907.13 KXL46563.1 - 2.3e-79 265.9 0.0 3.1e-79 265.5 0.0 1.2 1 0 0 1 1 1 1 Spo7-like protein Mit_KHE1 PF10173.9 KXL46564.1 - 7.8e-61 205.5 0.8 7.8e-61 205.5 0.8 1.6 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related Cutinase PF01083.22 KXL46565.1 - 7.3e-35 120.5 5.4 1.2e-30 106.8 3.2 2.1 1 1 1 2 2 2 2 Cutinase PE-PPE PF08237.11 KXL46565.1 - 0.00033 20.3 0.4 0.00044 19.9 0.4 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_6 PF12697.7 KXL46565.1 - 0.096 13.3 0.1 0.1 13.2 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Glyco_hydro_92 PF07971.12 KXL46566.1 - 2.2e-95 320.3 2.0 2.8e-95 319.9 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KXL46566.1 - 2.9e-61 207.4 1.4 2.9e-61 207.4 1.4 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 92 N-terminal domain DUF5494 PF17598.2 KXL46566.1 - 0.18 11.9 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5494) Carn_acyltransf PF00755.20 KXL46567.1 - 1.6e-206 687.5 0.0 1.8e-206 687.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Ldh_1_C PF02866.18 KXL46568.1 - 1.4e-45 155.2 0.0 2.9e-45 154.2 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KXL46568.1 - 5.6e-44 149.7 0.0 8.4e-44 149.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KXL46568.1 - 0.0016 17.5 0.0 0.0023 17.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KXL46568.1 - 0.05 14.0 0.6 0.17 12.4 0.0 2.1 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.16 KXL46568.1 - 0.07 12.7 0.0 0.26 10.8 0.1 1.9 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase Ion_trans_2 PF07885.16 KXL46569.1 - 6.4e-27 93.3 28.5 7.2e-17 61.1 3.2 3.5 3 1 1 4 4 4 2 Ion channel Lig_chan PF00060.26 KXL46569.1 - 1.2 8.9 10.7 0.085 12.7 1.1 3.2 2 1 0 2 2 2 0 Ligand-gated ion channel Phage_holin_4_2 PF04020.13 KXL46569.1 - 2.6 8.8 10.0 0.44 11.2 2.8 3.1 3 0 0 3 3 3 0 Mycobacterial 4 TMS phage holin, superfamily IV PPR_long PF17177.4 KXL46570.1 - 1.5e-19 70.2 0.1 1.8e-09 37.3 0.4 2.8 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 KXL46570.1 - 8e-17 61.2 0.3 0.0006 20.0 0.0 7.4 7 0 0 7 7 7 3 PPR repeat family PPR PF01535.20 KXL46570.1 - 7.2e-16 57.3 0.6 0.19 12.1 0.0 9.3 10 0 0 10 10 10 5 PPR repeat PPR_3 PF13812.6 KXL46570.1 - 5.7e-09 35.9 0.0 0.0089 16.1 0.0 5.3 5 2 2 7 7 7 3 Pentatricopeptide repeat domain TPR_14 PF13428.6 KXL46570.1 - 2.4e-07 31.0 1.2 5.2 8.2 0.0 6.2 5 0 0 5 5 5 3 Tetratricopeptide repeat PPR_1 PF12854.7 KXL46570.1 - 1.9e-06 27.5 0.0 4.9 7.0 0.0 5.5 5 0 0 5 5 5 3 PPR repeat TPR_1 PF00515.28 KXL46570.1 - 0.0051 16.6 0.8 14 5.7 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KXL46570.1 - 0.017 14.9 4.2 8.9 6.3 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXL46570.1 - 0.045 14.1 1.9 2.7 8.3 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXL46570.1 - 3.5 8.1 6.0 12 6.5 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat HSP70 PF00012.20 KXL46571.1 - 7.7e-157 523.0 10.8 1.5e-151 505.6 0.1 3.0 1 1 2 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 KXL46571.1 - 6.2e-12 45.0 0.0 3.6e-11 42.5 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein Ketoacyl-synt_C PF02801.22 KXL46571.1 - 0.022 14.8 0.8 0.054 13.5 0.0 2.1 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain Alanine_zipper PF11839.8 KXL46571.1 - 0.24 11.8 26.9 1 9.8 26.9 2.2 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein FtsA PF14450.6 KXL46571.1 - 0.32 11.4 0.0 0.32 11.4 0.0 3.2 3 1 0 3 3 3 0 Cell division protein FtsA MutL_C PF08676.11 KXL46572.1 - 4.8e-25 88.0 0.0 1.2e-24 86.8 0.0 1.7 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KXL46572.1 - 1.9e-20 72.7 0.1 9.8e-20 70.4 0.0 2.2 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KXL46572.1 - 2.8e-11 43.4 0.6 7.5e-11 42.0 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KXL46572.1 - 3.7e-07 30.6 0.0 1.2e-06 29.0 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1387 PF07139.11 KXL46572.1 - 0.0048 16.7 4.4 0.0048 16.7 4.4 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1387) Rhodanese PF00581.20 KXL46573.1 - 4.2e-19 69.0 0.0 5.8e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain EIF_2_alpha PF07541.12 KXL46575.1 - 4.3e-38 130.0 0.0 8.8e-38 129.0 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KXL46575.1 - 1.2e-13 51.2 0.8 2.4e-13 50.2 0.8 1.5 1 0 0 1 1 1 1 S1 RNA binding domain Treacle PF03546.14 KXL46575.1 - 0.0065 15.4 1.0 0.0089 14.9 1.0 1.1 1 0 0 1 1 1 1 Treacher Collins syndrome protein Treacle FmiP_Thoc5 PF09766.9 KXL46575.1 - 0.012 15.0 0.1 0.018 14.3 0.1 1.2 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 Cellulase PF00150.18 KXL46576.1 - 1.5e-28 100.0 3.3 2.4e-28 99.4 3.3 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.6 KXL46576.1 - 0.00022 20.9 0.4 0.00035 20.3 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Cas_csx3 PF09620.10 KXL46576.1 - 0.048 13.5 0.1 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) DUF295 PF03478.18 KXL46576.1 - 0.14 11.7 0.0 0.37 10.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF295) GFA PF04828.14 KXL46577.1 - 3.2e-10 40.2 2.2 5.7e-10 39.4 2.2 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme PH_4 PF15404.6 KXL46578.1 - 4.2e-63 212.4 0.2 9.8e-63 211.3 0.2 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Spo7_2_N PF15407.6 KXL46578.1 - 2.4e-16 59.1 0.4 2.4e-16 59.1 0.4 1.9 2 0 0 2 2 2 1 Sporulation protein family 7 PH PF00169.29 KXL46578.1 - 1.5e-08 35.1 0.3 0.44 11.1 0.0 5.4 4 1 0 4 4 4 2 PH domain PH_6 PF15406.6 KXL46578.1 - 0.025 14.9 0.0 0.11 12.8 0.0 2.1 1 0 0 1 1 1 0 Pleckstrin homology domain zf-C2H2_assoc PF16606.5 KXL46578.1 - 0.08 13.2 1.7 0.63 10.3 0.3 2.6 2 0 0 2 2 2 0 Unstructured conserved, between two C2H2-type zinc-fingers AA_permease_2 PF13520.6 KXL46579.1 - 4.3e-57 193.9 59.9 5.2e-57 193.6 59.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXL46579.1 - 1.1e-18 67.2 45.8 1.4e-18 66.7 45.8 1.1 1 0 0 1 1 1 1 Amino acid permease E1-E2_ATPase PF00122.20 KXL46580.1 - 7.9 6.0 8.4 1.1 8.7 2.5 2.2 1 1 1 2 2 2 0 E1-E2 ATPase ADP_ribosyl_GH PF03747.14 KXL46581.1 - 3.9e-46 158.1 0.2 6.3e-46 157.4 0.2 1.3 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase DASH_Dad2 PF08654.10 KXL46582.1 - 0.00058 20.2 0.2 0.0013 19.1 0.3 1.6 2 0 0 2 2 2 1 DASH complex subunit Dad2 BLOC1_2 PF10046.9 KXL46582.1 - 0.0022 18.3 0.1 0.0037 17.5 0.1 1.5 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 COG6 PF06419.11 KXL46582.1 - 0.0065 14.7 1.2 0.0077 14.5 1.2 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 XhlA PF10779.9 KXL46582.1 - 0.012 15.8 0.5 0.023 14.9 0.5 1.4 1 0 0 1 1 1 0 Haemolysin XhlA CENP-Q PF13094.6 KXL46582.1 - 0.013 15.7 2.3 0.03 14.5 2.3 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit CorA PF01544.18 KXL46582.1 - 0.032 13.5 0.4 0.043 13.1 0.4 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Sipho_Gp157 PF05565.11 KXL46582.1 - 0.035 14.1 0.1 0.04 13.9 0.1 1.2 1 0 0 1 1 1 0 Siphovirus Gp157 YlqD PF11068.8 KXL46582.1 - 0.045 14.1 0.7 0.15 12.5 0.6 1.9 2 0 0 2 2 2 0 YlqD protein zf-CpG_bind_C PF12269.8 KXL46582.1 - 0.06 13.1 0.7 0.08 12.7 0.7 1.1 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain DUF3287 PF11690.8 KXL46582.1 - 1.9 8.2 5.5 4.8 6.9 1.6 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3287) AA_permease_2 PF13520.6 KXL46583.1 - 6.4e-61 206.5 46.6 8.2e-61 206.1 46.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXL46583.1 - 1.6e-15 56.7 39.1 2e-15 56.4 39.1 1.1 1 0 0 1 1 1 1 Amino acid permease DOCK_N PF16172.5 KXL46584.1 - 1.1e-97 327.4 0.0 1.1e-97 327.4 0.0 1.6 2 0 0 2 2 2 1 DOCK N-terminus DHR-2 PF06920.13 KXL46584.1 - 1.5e-43 149.3 4.3 7e-43 147.1 4.3 1.9 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 KXL46584.1 - 5.5e-34 117.7 0.0 1.2e-33 116.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins SH3_9 PF14604.6 KXL46584.1 - 7.1e-08 32.2 0.0 8.5e-06 25.5 0.0 3.3 3 0 0 3 3 3 1 Variant SH3 domain SH3_1 PF00018.28 KXL46584.1 - 0.00044 19.8 0.0 0.0011 18.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXL46584.1 - 0.0018 17.9 0.0 0.0046 16.6 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain UvdE PF03851.14 KXL46585.1 - 1.7e-111 371.9 0.0 2.3e-111 371.5 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE CorA PF01544.18 KXL46586.1 - 5.2e-11 42.4 0.3 5.2e-11 42.4 0.3 2.6 3 0 0 3 3 3 1 CorA-like Mg2+ transporter protein Phage_holin_3_6 PF07332.11 KXL46586.1 - 0.089 12.8 0.6 0.16 12.0 0.6 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III SUR7 PF06687.12 KXL46586.1 - 0.11 12.1 1.3 0.2 11.3 1.3 1.3 1 0 0 1 1 1 0 SUR7/PalI family DUF3788 PF12663.7 KXL46587.1 - 0.045 13.7 0.1 0.061 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3788) PTH2 PF01981.16 KXL46588.1 - 1.3e-46 157.6 0.3 1.7e-46 157.3 0.3 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Sulfatase PF00884.23 KXL46589.1 - 8.6e-57 192.9 0.0 1.2e-56 192.4 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 KXL46589.1 - 4.1e-22 77.7 6.6 6.4e-22 77.1 2.8 2.4 1 1 1 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 KXL46589.1 - 5e-10 39.5 0.1 0.00016 21.4 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 KXL46589.1 - 0.0044 17.7 0.2 0.018 15.8 0.1 2.0 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF229 PF02995.17 KXL46589.1 - 0.005 15.5 0.0 0.008 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4976 PF16347.5 KXL46589.1 - 0.0097 16.2 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) DUF4994 PF16385.5 KXL46589.1 - 0.065 13.2 0.0 2.4 8.1 0.0 2.4 1 1 0 1 1 1 0 Domain of unknown function PIR PF00399.19 KXL46590.1 - 1.1e-07 31.1 47.3 0.0017 17.8 2.5 7.8 7 0 0 7 7 7 7 Yeast PIR protein repeat TMEM71 PF15121.6 KXL46590.1 - 0.22 11.2 8.2 2.6 7.7 2.2 2.7 1 1 1 2 2 2 0 TMEM71 protein family MFS_1 PF07690.16 KXL46591.1 - 7.3e-32 110.6 43.7 7.3e-32 110.6 43.7 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4153 PF13687.6 KXL46591.1 - 0.002 17.8 3.0 0.002 17.8 3.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4153) Amidohydro_1 PF01979.20 KXL46592.1 - 8.7e-05 22.0 0.0 0.00014 21.3 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXL46592.1 - 0.00033 20.3 0.0 0.0057 16.2 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase family DUF4945 PF16303.5 KXL46592.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4945) C2 PF00168.30 KXL46593.1 - 9.6e-29 99.7 0.2 2.8e-17 62.9 0.0 3.3 3 0 0 3 3 3 2 C2 domain p450 PF00067.22 KXL46594.1 - 9.1e-60 202.7 0.0 2.4e-59 201.3 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Calcipressin PF04847.12 KXL46595.1 - 1.8e-42 145.2 0.1 2.7e-42 144.6 0.1 1.2 1 0 0 1 1 1 1 Calcipressin DUF1631 PF07793.11 KXL46595.1 - 0.057 11.9 0.3 0.076 11.4 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Ribonuclease_3 PF00636.26 KXL46596.1 - 4.1e-41 139.9 0.0 2.7e-23 82.6 0.0 3.1 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KXL46596.1 - 2e-25 89.4 0.0 4.7e-12 46.2 0.0 4.0 3 2 0 3 3 3 2 Ribonuclease-III-like Dicer_dimer PF03368.14 KXL46596.1 - 1.3e-21 76.6 0.1 5.4e-20 71.4 0.0 2.7 2 0 0 2 2 2 1 Dicer dimerisation domain DEAD PF00270.29 KXL46596.1 - 1.5e-16 60.7 0.0 4.1e-16 59.2 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXL46596.1 - 2.4e-15 56.8 0.2 6e-15 55.5 0.2 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL46596.1 - 4.9e-12 46.2 0.0 1.6e-11 44.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit dsrm PF00035.26 KXL46596.1 - 0.12 13.1 0.0 0.49 11.1 0.0 2.1 2 0 0 2 2 2 0 Double-stranded RNA binding motif Nbs1_C PF08599.10 KXL46596.1 - 0.14 12.3 0.4 0.68 10.1 0.4 2.2 2 0 0 2 2 2 0 DNA damage repair protein Nbs1 Proteasome PF00227.26 KXL46597.1 - 1.4e-56 191.0 0.0 2.9e-32 111.7 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KXL46597.1 - 9.6e-11 41.2 0.1 3.2e-10 39.5 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RINGv PF12906.7 KXL46598.1 - 1e-09 38.4 5.1 1.2e-09 38.2 1.1 2.3 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.6 KXL46598.1 - 0.014 15.7 3.9 0.24 11.7 1.4 2.3 2 0 0 2 2 2 0 Ring finger domain Herpes_TK_C PF08465.10 KXL46598.1 - 0.069 12.9 0.3 0.15 11.8 0.3 1.5 1 0 0 1 1 1 0 Thymidine kinase from Herpesvirus C-terminal ATPase_gene1 PF09527.10 KXL46598.1 - 0.087 13.0 0.1 0.087 13.0 0.1 2.5 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter PHD_4 PF16866.5 KXL46598.1 - 5 7.3 12.5 0.45 10.6 3.2 2.7 3 0 0 3 3 3 0 PHD-finger PHD PF00628.29 KXL46598.1 - 5.3 7.0 8.8 0.3 11.0 3.3 1.7 2 0 0 2 2 2 0 PHD-finger HTH_psq PF05225.16 KXL46599.1 - 0.012 15.3 0.1 0.018 14.8 0.1 1.2 1 0 0 1 1 1 0 helix-turn-helix, Psq domain NUMOD1 PF07453.13 KXL46599.1 - 0.11 12.8 0.1 0.17 12.2 0.1 1.3 1 0 0 1 1 1 0 NUMOD1 domain DNApol_Exo PF18136.1 KXL46601.1 - 1.2e-102 342.8 0.0 1.9e-102 342.2 0.0 1.3 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 KXL46601.1 - 4.9e-55 187.1 0.0 7.9e-55 186.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A Mad3_BUB1_I PF08311.12 KXL46601.1 - 0.19 11.7 0.1 0.45 10.5 0.1 1.5 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 zf-C3HC4_3 PF13920.6 KXL46602.1 - 2.5e-10 40.1 6.7 3.7e-10 39.5 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXL46602.1 - 4e-09 36.7 6.3 6.3e-09 36.0 6.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KXL46602.1 - 4.9e-09 36.1 5.6 1.1e-08 35.0 5.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KXL46602.1 - 3e-08 33.4 5.2 5.5e-08 32.5 5.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KXL46602.1 - 5.3e-08 32.6 6.6 8.6e-08 31.9 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXL46602.1 - 1.9e-07 30.9 6.8 3.1e-07 30.2 6.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KXL46602.1 - 4.3e-07 29.7 8.4 1.5e-06 27.9 8.5 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXL46602.1 - 0.0029 17.8 3.1 0.0067 16.7 3.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KXL46602.1 - 0.0089 16.2 6.2 0.016 15.3 6.2 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KXL46602.1 - 0.027 14.3 5.1 0.054 13.3 5.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zinc_ribbon_9 PF14369.6 KXL46602.1 - 0.06 13.6 0.4 0.16 12.3 0.4 1.7 1 0 0 1 1 1 0 zinc-ribbon zf-ANAPC11 PF12861.7 KXL46602.1 - 0.44 10.6 2.2 0.77 9.9 2.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FYVE PF01363.21 KXL46602.1 - 0.74 10.0 5.5 2.6 8.3 6.0 1.6 1 1 0 1 1 1 0 FYVE zinc finger zf-UDP PF14569.6 KXL46602.1 - 1 9.5 3.4 2.2 8.4 3.4 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_11 PF17123.5 KXL46602.1 - 5 7.0 8.9 2.3 8.0 6.6 1.7 2 0 0 2 2 2 0 RING-like zinc finger PX PF00787.24 KXL46603.1 - 7.2e-16 58.2 0.0 1.1e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 PX domain DNA_pol_phi PF04931.13 KXL46604.1 - 7.2 4.6 5.4 6.8 4.7 5.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi Ribosomal_L32e PF01655.18 KXL46605.1 - 7.4e-51 171.1 0.9 1.1e-50 170.6 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L32 RL10P_insert PF17777.1 KXL46606.1 - 1.7e-22 79.2 0.0 2.6e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KXL46606.1 - 5.6e-20 71.3 0.0 8.6e-20 70.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 Sulfotransfer_4 PF17784.1 KXL46607.1 - 8.4e-58 195.7 0.1 9.8e-58 195.5 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXL46607.1 - 8.8e-05 23.0 0.6 0.0077 16.6 0.6 2.2 1 1 0 1 1 1 1 Sulfotransferase family Arylsulfotran_2 PF14269.6 KXL46608.1 - 4.8e-52 177.2 0.7 7.1e-52 176.6 0.7 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXL46608.1 - 5.5e-16 58.4 0.2 8.7e-16 57.8 0.2 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) HTH_Tnp_Tc5 PF03221.16 KXL46609.1 - 0.00066 19.7 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain L51_S25_CI-B8 PF05047.16 KXL46610.1 - 3.5e-16 58.9 0.1 5.7e-16 58.2 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain U1snRNP70_N PF12220.8 KXL46611.1 - 5e-23 81.5 1.7 5e-23 81.5 1.7 1.7 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 KXL46611.1 - 4.7e-15 55.2 0.2 3.2e-06 26.9 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXL46611.1 - 2.8e-05 24.2 0.0 0.00012 22.1 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif PHM7_cyt PF14703.6 KXL46611.1 - 0.063 13.5 0.3 0.25 11.5 0.2 1.8 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter TIM PF00121.18 KXL46612.1 - 1.1e-88 296.7 0.3 1.3e-88 296.5 0.3 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase ALIX_LYPXL_bnd PF13949.6 KXL46614.1 - 0.0013 18.1 0.2 0.0024 17.2 0.2 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV RasGAP_C PF03836.15 KXL46614.1 - 0.0025 18.0 0.4 0.0062 16.7 0.4 1.7 1 0 0 1 1 1 1 RasGAP C-terminus Fungal_trans PF04082.18 KXL46615.1 - 1.5e-18 66.8 3.4 2.3e-18 66.2 3.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KXL46615.1 - 1.9e-06 28.1 14.4 6.3e-05 23.2 5.4 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KXL46615.1 - 0.0004 20.7 13.9 0.091 13.3 5.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXL46615.1 - 0.0015 19.2 12.1 0.34 11.9 0.9 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger RasGEF PF00617.19 KXL46619.1 - 1.1e-60 204.8 0.5 2.2e-60 203.9 0.5 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KXL46619.1 - 3.5e-27 94.7 0.1 7.3e-27 93.7 0.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 KXL46619.1 - 2.7e-15 55.7 0.1 5.2e-15 54.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXL46619.1 - 4.2e-14 52.1 0.1 8.6e-14 51.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXL46619.1 - 7.5e-13 47.9 0.1 1.6e-12 46.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 KXL46619.1 - 0.0002 21.4 0.0 0.00043 20.3 0.0 1.6 1 0 0 1 1 1 1 WW domain AA_permease_2 PF13520.6 KXL46620.1 - 5.6e-48 163.8 58.3 7.1e-48 163.5 58.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXL46620.1 - 7.5e-14 51.2 55.0 1.3e-13 50.4 55.0 1.3 1 1 0 1 1 1 1 Amino acid permease TauD PF02668.16 KXL46621.1 - 1.2e-52 179.4 0.6 1.4e-52 179.2 0.6 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Ras PF00071.22 KXL46623.1 - 2.5e-31 108.5 0.2 3.3e-31 108.1 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXL46623.1 - 9.4e-24 83.9 0.1 1.6e-23 83.2 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXL46623.1 - 8.2e-07 28.6 0.1 1.1e-06 28.3 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KXL46623.1 - 0.00012 21.5 0.2 0.00016 21.1 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 KXL46623.1 - 0.013 14.3 0.1 1.7 7.4 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) G-alpha PF00503.20 KXL46623.1 - 0.052 12.7 0.3 0.15 11.2 0.0 1.9 1 1 1 2 2 2 0 G-protein alpha subunit AAA_7 PF12775.7 KXL46623.1 - 0.14 11.6 0.8 0.77 9.2 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region WD40 PF00400.32 KXL46624.1 - 3.2e-14 53.1 9.9 9.3e-07 29.5 0.1 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 KXL46624.1 - 3.6e-13 49.6 0.0 1.1e-12 48.0 0.0 1.9 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 KXL46624.1 - 1.2e-07 31.9 1.1 0.0019 18.5 0.1 3.5 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 KXL46624.1 - 0.32 9.9 1.5 0.45 9.4 0.5 1.7 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain KRE1 PF17056.5 KXL46626.1 - 5e-05 22.9 5.0 5e-05 22.9 5.0 1.9 2 0 0 2 2 2 1 Killer toxin-resistance protein 1 Oxidored_FMN PF00724.20 KXL46627.1 - 1.5e-08 34.3 0.0 1.7e-08 34.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF4965 PF16335.5 KXL46628.1 - 1e-70 236.9 0.4 2e-70 235.9 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF5127 PF17168.4 KXL46628.1 - 2.7e-68 230.2 13.5 7.1e-43 147.0 3.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF5127) DUF1793 PF08760.11 KXL46628.1 - 3.2e-56 190.3 0.3 3.2e-56 190.3 0.3 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KXL46628.1 - 0.00083 18.9 0.0 0.0029 17.1 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Fungal_trans PF04082.18 KXL46629.1 - 9.4e-11 41.2 0.6 1.3e-10 40.8 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DHR10 PF18595.1 KXL46629.1 - 0.065 13.3 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain PAXX PF15384.6 KXL46629.1 - 0.17 11.6 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 WD40 PF00400.32 KXL46631.1 - 3.9e-13 49.7 0.4 6.1e-08 33.2 0.1 5.3 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL46631.1 - 2.8e-07 30.7 0.0 0.78 10.1 0.0 3.6 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXL46631.1 - 0.0013 18.7 0.0 7.8 6.3 0.0 3.7 3 1 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A Herpes_UL37_1 PF03970.13 KXL46631.1 - 0.016 14.4 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL37 tegument protein Mito_carr PF00153.27 KXL46632.1 - 3.2e-53 177.6 1.0 3.3e-18 65.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein UCH PF00443.29 KXL46633.1 - 4.1e-34 118.2 0.0 1.3e-33 116.6 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXL46633.1 - 5.8e-05 22.8 0.2 0.0013 18.4 0.2 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Alb1 PF09135.11 KXL46634.1 - 9.9e-18 65.0 15.3 2.6e-17 63.6 15.3 1.7 1 1 0 1 1 1 1 Alb1 PUL PF08324.11 KXL46635.1 - 1e-49 169.3 4.4 1.4e-49 168.8 4.4 1.2 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.14 KXL46635.1 - 7e-40 136.3 0.0 1.1e-39 135.7 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.20 KXL46635.1 - 1.1e-16 60.7 0.0 3.2e-16 59.2 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin OST3_OST6 PF04756.13 KXL46635.1 - 6.7e-07 28.9 0.1 1.3e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family TraF PF13728.6 KXL46635.1 - 0.00015 21.7 0.1 0.00047 20.1 0.0 1.8 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 KXL46635.1 - 0.00018 22.0 0.8 0.0021 18.5 0.4 2.5 2 1 0 2 2 2 1 Thioredoxin-like domain T4_deiodinase PF00837.17 KXL46635.1 - 0.011 15.1 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Iodothyronine deiodinase Thioredoxin_8 PF13905.6 KXL46635.1 - 0.025 14.9 0.0 0.074 13.4 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like DSBA PF01323.20 KXL46635.1 - 0.046 13.5 0.4 0.71 9.6 0.1 2.3 1 1 1 2 2 2 0 DSBA-like thioredoxin domain PAN_4 PF14295.6 KXL46636.1 - 2.3e-08 33.8 45.5 0.19 11.7 1.1 8.0 7 0 0 7 7 7 7 PAN domain AMP-binding PF00501.28 KXL46637.1 - 1e-78 264.8 0.0 1.3e-78 264.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXL46637.1 - 2.1e-17 63.9 0.3 5.5e-17 62.5 0.3 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Sugar_tr PF00083.24 KXL46638.1 - 1.4e-98 330.7 20.4 1.6e-98 330.5 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL46638.1 - 3.2e-21 75.6 32.7 4.4e-17 62.0 13.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXL46638.1 - 3.4e-05 22.5 1.0 3.4e-05 22.5 1.0 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) TPR_12 PF13424.6 KXL46639.1 - 0.016 15.5 0.1 0.068 13.5 0.2 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat PRIMA1 PF16101.5 KXL46640.1 - 1 9.4 6.4 1 9.4 6.4 1.1 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 SH3_1 PF00018.28 KXL46641.1 - 2.9e-28 97.2 2.7 1.7e-14 53.1 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KXL46641.1 - 5.5e-27 93.4 3.4 1.1e-12 47.6 0.6 2.5 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.20 KXL46641.1 - 2.1e-14 53.3 0.0 3.5e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.17 KXL46641.1 - 2.4e-13 49.5 0.0 5.4e-07 29.2 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain F-box PF00646.33 KXL46642.1 - 7.5e-05 22.5 0.0 0.00019 21.2 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXL46642.1 - 8.6e-05 22.3 0.4 0.0002 21.2 0.4 1.7 1 0 0 1 1 1 1 F-box-like MMS19_N PF14500.6 KXL46643.1 - 1.3e-89 300.3 2.4 2.1e-89 299.6 0.1 2.6 4 0 0 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 KXL46643.1 - 1.5e-68 231.9 8.4 1.7e-68 231.7 3.2 2.9 3 1 0 3 3 3 1 RNAPII transcription regulator C-terminal HEAT_2 PF13646.6 KXL46643.1 - 0.0053 17.1 6.6 0.027 14.9 0.4 4.6 5 0 0 5 5 5 1 HEAT repeats UME PF08064.13 KXL46643.1 - 0.01 15.7 1.3 6.5 6.7 0.0 5.0 5 0 0 5 5 5 0 UME (NUC010) domain Corona_NS1 PF06145.11 KXL46643.1 - 0.032 13.7 0.1 0.075 12.6 0.1 1.7 1 0 0 1 1 1 0 Coronavirus nonstructural protein NS1 Sec3_C_2 PF15278.6 KXL46643.1 - 0.041 14.2 0.5 2.2 8.7 0.1 3.2 3 0 0 3 3 3 0 Sec3 exocyst complex subunit HEAT_EZ PF13513.6 KXL46643.1 - 0.22 12.1 11.3 0.047 14.2 3.4 4.0 4 0 0 4 4 4 0 HEAT-like repeat THF_DHG_CYH PF00763.23 KXL46644.1 - 2.4e-23 82.6 0.0 3.7e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 KXL46644.1 - 1e-13 50.9 0.0 9.2e-09 34.8 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain PCI PF01399.27 KXL46645.1 - 3e-14 53.4 0.0 1e-13 51.7 0.0 2.0 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.9 KXL46645.1 - 4.2e-05 23.3 0.2 8.5e-05 22.3 0.2 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_19 PF14559.6 KXL46645.1 - 0.011 16.3 0.1 5.6 7.6 0.0 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_21 PF09976.9 KXL46645.1 - 0.011 15.4 1.0 0.05 13.3 0.7 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain TPR_2 PF07719.17 KXL46645.1 - 0.02 15.0 0.0 3.3 8.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribonuc_red_sm PF00268.21 KXL46645.1 - 0.028 13.9 0.1 0.052 13.0 0.1 1.3 1 0 0 1 1 1 0 Ribonucleotide reductase, small chain TFIIF_beta PF02270.15 KXL46646.1 - 1.1e-26 92.7 0.2 2e-26 91.9 0.2 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 KXL46646.1 - 5.7e-26 91.8 0.3 8.4e-26 91.3 0.3 1.2 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus MFS_1 PF07690.16 KXL46647.1 - 3.4e-40 138.0 46.5 1.1e-39 136.4 46.0 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL46647.1 - 1.5e-13 50.4 9.9 1.5e-13 50.4 9.9 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 KXL46647.1 - 1.6e-05 24.3 7.9 1.6e-05 24.3 7.9 3.2 1 1 1 3 3 3 2 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 KXL46647.1 - 0.037 12.3 11.4 0.055 11.8 2.1 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family FAD_binding_3 PF01494.19 KXL46648.1 - 1.4e-17 64.0 0.1 3e-09 36.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KXL46648.1 - 3.6e-08 33.4 12.4 0.0005 19.7 0.1 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXL46648.1 - 6.6e-07 29.5 1.8 1.6e-06 28.3 1.8 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KXL46648.1 - 8.7e-07 28.6 1.7 1.3e-06 28.1 1.7 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KXL46648.1 - 4e-06 25.9 6.5 0.0064 15.4 3.3 3.3 3 1 0 3 3 3 2 Tryptophan halogenase Amino_oxidase PF01593.24 KXL46648.1 - 0.00011 21.7 4.1 0.078 12.3 0.0 2.5 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Rossmann-like PF10727.9 KXL46648.1 - 0.00016 21.6 0.9 0.00039 20.3 0.9 1.6 1 0 0 1 1 1 1 Rossmann-like domain Pyr_redox PF00070.27 KXL46648.1 - 0.00018 22.0 4.5 0.00044 20.8 0.8 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXL46648.1 - 0.00022 20.6 9.7 0.0022 17.3 4.3 2.4 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXL46648.1 - 0.0038 16.4 9.0 0.011 14.9 7.5 2.0 1 1 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KXL46648.1 - 0.0086 15.2 8.8 0.0086 15.2 8.8 2.4 3 0 0 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.12 KXL46648.1 - 0.013 14.6 4.3 0.12 11.4 4.4 2.1 1 1 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 KXL46648.1 - 0.028 13.6 2.6 0.053 12.8 2.6 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KXL46648.1 - 0.03 13.0 10.3 0.036 12.8 5.9 2.1 2 0 0 2 2 2 0 HI0933-like protein 3HCDH_N PF02737.18 KXL46648.1 - 0.092 12.6 2.4 0.19 11.6 2.4 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KXL46648.1 - 0.13 12.3 3.4 0.82 9.6 3.4 2.1 1 1 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KXL46648.1 - 0.31 10.2 5.6 0.57 9.4 4.3 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXL46648.1 - 0.65 9.3 7.2 0.46 9.7 5.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain zf-C2H2_4 PF13894.6 KXL46649.1 - 0.0016 19.1 11.0 0.055 14.3 0.3 4.6 3 1 0 3 3 3 1 C2H2-type zinc finger zf-LYAR PF08790.11 KXL46649.1 - 0.13 12.2 0.7 14 5.7 0.1 2.8 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_3rep PF18868.1 KXL46649.1 - 0.17 12.6 2.2 1.7 9.3 1.9 2.2 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 KXL46649.1 - 0.38 11.1 7.7 0.5 10.7 0.2 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KXL46649.1 - 3.1 8.4 13.9 1.5 9.4 0.2 3.9 3 1 0 3 3 3 0 Zinc finger, C2H2 type Abhydrolase_3 PF07859.13 KXL46650.1 - 7e-24 84.9 0.0 7.3e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF826 PF05696.11 KXL46651.1 - 0.039 14.0 0.0 0.074 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF826) eIF-3_zeta PF05091.12 KXL46652.1 - 7.7e-205 681.8 0.0 9.5e-205 681.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.13 KXL46652.1 - 0.081 12.6 0.0 0.21 11.3 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF569) Prenyltransf PF01255.19 KXL46653.1 - 2.6e-05 23.9 0.0 0.0002 21.0 0.0 1.9 2 0 0 2 2 2 1 Putative undecaprenyl diphosphate synthase SecG PF03840.14 KXL46654.1 - 0.033 14.3 1.3 0.063 13.4 0.3 2.1 2 0 0 2 2 2 0 Preprotein translocase SecG subunit Aa_trans PF01490.18 KXL46655.1 - 1.5e-27 96.3 29.5 1.9e-27 96.0 29.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 KXL46655.1 - 5.9e-06 25.4 26.7 5.9e-06 25.4 26.7 2.1 1 1 1 2 2 2 2 Amino acid permease PIR PF00399.19 KXL46657.1 - 3.7e-07 29.5 6.7 3.7e-07 29.5 6.7 2.8 2 0 0 2 2 2 1 Yeast PIR protein repeat RIFIN PF02009.16 KXL46657.1 - 0.27 11.1 5.1 0.34 10.8 5.1 1.0 1 0 0 1 1 1 0 Rifin Sugar_tr PF00083.24 KXL46659.1 - 9e-26 90.7 20.0 2.1e-23 83.0 20.0 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter AA_permease_2 PF13520.6 KXL46660.1 - 3.6e-64 217.2 47.6 4.2e-64 216.9 47.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXL46660.1 - 7e-15 54.6 34.8 9.5e-15 54.1 34.8 1.2 1 0 0 1 1 1 1 Amino acid permease Gln_deamidase_2 PF18626.1 KXL46660.1 - 0.072 13.3 0.1 0.22 11.8 0.0 1.7 2 0 0 2 2 2 0 Glutaminase Peptidase_S8 PF00082.22 KXL46662.1 - 6.9e-29 101.0 11.9 2.9e-28 99.0 11.9 1.7 1 1 0 1 1 1 1 Subtilase family UQ_con PF00179.26 KXL46664.1 - 1.3e-38 131.8 0.0 3.8e-28 97.9 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXL46664.1 - 3.9e-08 33.1 0.0 0.012 15.3 0.0 2.5 2 0 0 2 2 2 2 Prokaryotic E2 family B UEV PF05743.13 KXL46664.1 - 0.035 14.0 0.1 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 UEV domain RWD PF05773.22 KXL46664.1 - 0.081 13.2 0.0 2.5 8.4 0.0 2.3 2 0 0 2 2 2 0 RWD domain UFC1 PF08694.11 KXL46664.1 - 0.18 11.5 0.0 0.93 9.1 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-fold modifier-conjugating enzyme 1 Sybindin PF04099.12 KXL46665.1 - 1.7e-42 144.8 0.0 2.1e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KXL46665.1 - 3.5e-06 27.2 0.0 4.8e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Nic96 PF04097.14 KXL46667.1 - 1.2e-211 704.4 0.0 1.5e-211 704.1 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.6 KXL46667.1 - 5.7e-05 23.9 38.2 8e-05 23.4 33.7 3.0 2 1 0 2 2 2 1 Nucleoporin FG repeat region RRM_1 PF00076.22 KXL46669.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Amidase PF01425.21 KXL46671.1 - 8.5e-118 394.2 0.0 1e-117 393.9 0.0 1.0 1 0 0 1 1 1 1 Amidase Per1 PF04080.13 KXL46672.1 - 1.1e-104 349.7 10.1 1.3e-104 349.5 10.1 1.1 1 0 0 1 1 1 1 Per1-like family Orai-1 PF07856.12 KXL46672.1 - 0.2 11.3 3.0 0.37 10.4 3.0 1.4 1 0 0 1 1 1 0 Mediator of CRAC channel activity CENP-F_N PF10481.9 KXL46673.1 - 0.0065 16.1 4.0 0.36 10.4 0.1 2.2 2 0 0 2 2 2 2 Cenp-F N-terminal domain DUF2046 PF09755.9 KXL46673.1 - 0.018 14.3 0.2 0.39 9.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Striatin PF08232.12 KXL46673.1 - 0.26 11.9 2.4 0.68 10.5 0.3 2.5 2 1 0 2 2 2 0 Striatin family SlyX PF04102.12 KXL46673.1 - 3.8 8.2 6.0 27 5.4 0.4 2.7 3 0 0 3 3 3 0 SlyX Amidohydro_1 PF01979.20 KXL46674.1 - 1.2e-76 258.3 0.1 1.3e-76 258.1 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXL46674.1 - 1.6e-09 37.8 4.5 4.1e-08 33.1 0.5 2.2 2 0 0 2 2 2 2 Amidohydrolase family IBR PF01485.21 KXL46675.1 - 1.1e-19 70.4 33.1 1.7e-10 41.0 8.7 3.8 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain FeS PF04060.13 KXL46675.1 - 9.2 6.0 12.5 5.9 6.6 2.3 3.2 2 1 0 2 2 2 0 Putative Fe-S cluster FCH PF00611.23 KXL46676.1 - 1.1e-14 54.4 0.0 3.7e-14 52.8 0.0 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Katanin_con80 PF13925.6 KXL46676.1 - 0.082 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 con80 domain of Katanin Rapsyn_N PF10579.9 KXL46676.1 - 0.15 12.2 0.1 0.31 11.2 0.1 1.5 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region Na_Ca_ex PF01699.24 KXL46677.1 - 1.7e-38 131.9 42.8 5.3e-20 71.9 18.0 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein CCDC106 PF15794.5 KXL46677.1 - 4.8 6.8 12.5 1.8 8.2 3.7 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 eIF-3c_N PF05470.12 KXL46678.1 - 5.8e-172 573.1 24.0 2.6e-140 468.6 3.2 3.2 2 1 0 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 KXL46678.1 - 3.8e-15 56.3 1.8 2e-14 53.9 0.0 3.2 3 0 0 3 3 3 1 PCI domain DUF2779 PF11074.8 KXL46678.1 - 0.42 11.1 3.6 1.6 9.2 0.1 3.3 2 2 1 3 3 3 0 Domain of unknown function(DUF2779) EAP30 PF04157.16 KXL46679.1 - 2.4e-66 223.4 0.0 2.7e-66 223.2 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Phage_TAC_11 PF11836.8 KXL46679.1 - 0.019 15.1 0.1 0.042 14.0 0.1 1.6 1 0 0 1 1 1 0 Phage tail tube protein, GTA-gp10 Ribosomal_L30_N PF08079.12 KXL46680.1 - 5.1e-27 93.9 22.2 5.1e-27 93.9 22.2 1.8 3 0 0 3 3 3 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KXL46680.1 - 8.9e-19 67.1 2.4 8.9e-19 67.1 2.4 2.1 2 1 1 3 3 3 1 Ribosomal protein L30p/L7e CSRNP_N PF16019.5 KXL46680.1 - 0.019 14.9 5.4 0.029 14.3 5.4 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Pox_L3_FP4 PF03339.14 KXL46680.1 - 0.5 9.3 2.7 0.64 9.0 1.9 1.5 2 0 0 2 2 2 0 Poxvirus L3/FP4 protein Pyr_redox_2 PF07992.14 KXL46681.1 - 1e-51 175.9 0.0 1.3e-51 175.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KXL46681.1 - 7.4e-19 68.0 0.0 1.9e-18 66.7 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KXL46681.1 - 1.9e-17 63.6 0.2 2.5e-16 60.0 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXL46681.1 - 6e-12 45.4 0.0 5.3e-10 39.0 0.0 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXL46681.1 - 2e-07 30.5 7.3 0.008 15.3 0.3 4.2 2 2 2 4 4 4 3 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KXL46681.1 - 1.7e-05 24.9 1.4 0.056 13.7 0.2 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 KXL46681.1 - 3.7e-05 23.1 0.0 8.5e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KXL46681.1 - 5.9e-05 23.5 0.1 0.0078 16.6 0.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 KXL46681.1 - 0.00026 20.9 0.2 0.029 14.3 0.0 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 KXL46681.1 - 0.00076 18.3 2.9 0.38 9.4 0.0 3.0 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_2 PF00890.24 KXL46681.1 - 0.00077 18.7 1.8 0.023 13.8 0.1 2.6 2 1 0 2 2 2 1 FAD binding domain UDPG_MGDP_dh_N PF03721.14 KXL46681.1 - 0.00094 18.8 4.7 0.0028 17.3 1.7 2.7 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain K_oxygenase PF13434.6 KXL46681.1 - 0.0014 17.9 0.0 0.078 12.1 0.2 2.2 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 KXL46681.1 - 0.0043 16.5 2.8 0.021 14.2 0.1 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase DAO PF01266.24 KXL46681.1 - 0.0046 16.6 0.7 0.12 11.9 0.1 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase XdhC_C PF13478.6 KXL46681.1 - 0.0061 17.1 0.0 0.58 10.7 0.0 2.8 2 1 0 2 2 2 1 XdhC Rossmann domain 2-Hacid_dh_C PF02826.19 KXL46681.1 - 0.021 14.2 0.4 0.021 14.2 0.4 2.5 3 1 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 KXL46681.1 - 0.17 10.9 0.2 12 4.8 0.0 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 KXL46681.1 - 0.45 10.5 4.1 0.53 10.3 0.1 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding ApbA PF02558.16 KXL46681.1 - 0.54 9.9 3.8 4.6 6.9 0.2 3.1 2 2 0 2 2 2 0 Ketopantoate reductase PanE/ApbA MS_channel PF00924.18 KXL46682.1 - 1.8e-18 66.9 3.2 3.1e-18 66.1 3.2 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KXL46682.1 - 0.0011 18.3 0.2 0.0026 17.2 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXL46682.1 - 0.011 15.6 0.1 0.029 14.3 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 KXL46682.1 - 0.03 14.8 0.1 0.075 13.5 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair PRIMA1 PF16101.5 KXL46682.1 - 0.095 12.7 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 EF-hand_5 PF13202.6 KXL46682.1 - 0.15 11.6 0.1 0.34 10.5 0.1 1.5 1 0 0 1 1 1 0 EF hand DUF1189 PF06691.11 KXL46682.1 - 8.2 5.9 8.7 6.4 6.3 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1189) DUF3043 PF11241.8 KXL46682.1 - 8.6 6.4 6.2 3 7.9 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3043) PI3_PI4_kinase PF00454.27 KXL46683.1 - 8.8e-54 183.0 0.0 1.7e-53 182.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.13 KXL46683.1 - 7.1e-30 102.9 0.6 4.8e-29 100.3 0.6 2.6 1 0 0 1 1 1 1 UME (NUC010) domain FAT PF02259.23 KXL46683.1 - 1.4e-24 87.0 4.5 4.1e-24 85.5 4.5 1.9 1 0 0 1 1 1 1 FAT domain FATC PF02260.20 KXL46683.1 - 6.5e-12 45.0 0.0 1.4e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 FATC domain DUF2408 PF10303.9 KXL46683.1 - 0.074 13.6 0.3 4 8.0 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) PET122 PF05476.11 KXL46683.1 - 0.12 11.7 0.4 0.5 9.6 0.4 2.1 1 1 0 1 1 1 0 PET122 HEAT_2 PF13646.6 KXL46683.1 - 0.14 12.6 2.4 18 5.8 0.0 4.9 3 1 0 3 3 3 0 HEAT repeats COX16 PF14138.6 KXL46684.1 - 9e-34 115.8 0.2 1.1e-33 115.5 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 OppC_N PF12911.7 KXL46684.1 - 0.012 15.5 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF1682 PF07946.14 KXL46684.1 - 0.33 10.1 2.4 0.43 9.8 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PFK PF00365.20 KXL46685.1 - 1.3e-181 602.2 0.4 2.8e-107 358.3 0.4 3.1 2 1 0 2 2 2 2 Phosphofructokinase DAGK_cat PF00781.24 KXL46685.1 - 0.13 11.9 0.2 0.41 10.3 0.2 1.8 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Med17 PF10156.9 KXL46686.1 - 3.1e-85 286.6 1.4 4.3e-85 286.1 1.4 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex ISN1 PF06437.11 KXL46687.1 - 1.4e-196 653.3 0.0 1.5e-196 653.2 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase TRM PF02005.16 KXL46688.1 - 1.1e-107 360.5 0.0 3.8e-92 309.4 0.0 2.1 1 1 1 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase TrmK PF04816.12 KXL46688.1 - 0.14 11.7 0.0 0.55 9.7 0.0 1.9 2 0 0 2 2 2 0 tRNA (adenine(22)-N(1))-methyltransferase Ferritin_2 PF13668.6 KXL46689.1 - 2.7e-17 63.2 0.0 4.5e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Snf7 PF03357.21 KXL46690.1 - 2.3e-13 50.1 7.6 3e-13 49.8 7.6 1.2 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 KXL46690.1 - 0.0096 15.9 2.4 0.015 15.2 2.4 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DMSP_lyase PF16867.5 KXL46690.1 - 0.011 15.4 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase SKA2 PF16740.5 KXL46690.1 - 0.21 11.4 3.6 2 8.2 0.2 2.8 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 YlqD PF11068.8 KXL46690.1 - 0.27 11.6 5.7 0.73 10.2 4.1 2.0 1 1 0 2 2 2 0 YlqD protein DUF1484 PF07363.11 KXL46690.1 - 6.3 7.9 9.9 29 5.7 0.4 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1484) TPP_enzyme_N PF02776.18 KXL46692.1 - 1.3e-55 187.6 0.0 4.2e-55 186.0 0.0 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KXL46692.1 - 3.4e-46 156.8 0.0 2.3e-45 154.1 0.0 2.5 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXL46692.1 - 4.2e-42 143.1 0.6 1.3e-41 141.6 0.1 2.1 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 KXL46692.1 - 0.02 14.6 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Spt20 PF12090.8 KXL46692.1 - 0.15 11.6 2.7 0.25 10.9 2.7 1.2 1 0 0 1 1 1 0 Spt20 family TPR_19 PF14559.6 KXL46693.1 - 0.0012 19.3 4.7 0.072 13.6 0.3 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat DNA_pol_B PF00136.21 KXL46694.1 - 2.5e-114 382.5 0.1 4.1e-114 381.8 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 KXL46694.1 - 4.3e-64 215.7 0.0 4.3e-64 215.7 0.0 1.7 2 0 0 2 2 2 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 KXL46694.1 - 1.7e-43 149.1 0.0 3.3e-43 148.1 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 KXL46694.1 - 2.7e-24 85.0 9.0 3.2e-24 84.8 5.1 2.7 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 KXL46694.1 - 0.0027 16.6 0.2 0.01 14.7 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral tRNA_NucTran2_2 PF13735.6 KXL46694.1 - 0.1 12.6 0.2 0.21 11.6 0.2 1.5 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative YL1 PF05764.13 KXL46694.1 - 5.1 7.1 12.7 10 6.1 12.7 1.5 1 0 0 1 1 1 0 YL1 nuclear protein Ribosomal_L13e PF01294.18 KXL46695.1 - 3.4e-77 258.4 7.3 3.4e-77 258.4 7.3 1.4 2 0 0 2 2 2 1 Ribosomal protein L13e Cas_Csy4 PF09618.10 KXL46695.1 - 7.7 6.6 10.1 1.4 9.0 1.4 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy4) ERG2_Sigma1R PF04622.12 KXL46697.1 - 6e-95 316.5 0.1 8.3e-95 316.0 0.1 1.2 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein GPI-anchored PF10342.9 KXL46698.1 - 2.3e-10 41.1 0.2 4.3e-10 40.2 0.0 1.5 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Cyt-b5 PF00173.28 KXL46700.1 - 4.6e-13 49.1 0.0 5.5e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3449 PF11931.8 KXL46701.1 - 0.0018 18.1 1.0 0.0037 17.1 1.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) Abhydrolase_3 PF07859.13 KXL46702.1 - 2.1e-46 158.5 0.1 2.6e-46 158.2 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXL46702.1 - 1.3e-06 27.6 0.0 1.8e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KXL46702.1 - 0.001 18.6 0.0 0.0025 17.3 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 KXL46702.1 - 0.0013 17.7 0.0 0.0016 17.4 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Fungal_trans PF04082.18 KXL46704.1 - 1.6e-18 66.7 0.0 2.7e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL46704.1 - 6.4e-08 32.6 9.1 1.1e-07 31.8 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AhpC-TSA PF00578.21 KXL46705.1 - 0.001 19.0 0.0 0.002 18.1 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family AhpC-TSA_2 PF13911.6 KXL46705.1 - 0.0018 18.4 0.0 0.0028 17.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.10 KXL46705.1 - 0.058 13.1 0.0 0.17 11.6 0.0 1.6 2 0 0 2 2 2 0 Redoxin Pribosyltran_N PF13793.6 KXL46707.1 - 2.8e-44 149.8 0.1 7.7e-44 148.4 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KXL46707.1 - 5.2e-34 117.9 0.0 2.9e-28 99.1 0.0 2.4 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KXL46707.1 - 5.9e-08 32.4 0.0 2.4e-05 23.9 0.1 2.4 2 0 0 2 2 2 2 Phosphoribosyl transferase domain PARM PF17061.5 KXL46707.1 - 7 6.7 13.0 0.12 12.5 5.5 1.7 2 0 0 2 2 2 0 PARM SelP_N PF04592.14 KXL46707.1 - 9.8 5.5 21.1 1 8.7 12.5 2.2 2 0 0 2 2 2 0 Selenoprotein P, N terminal region UPF0121 PF03661.13 KXL46708.1 - 1.6e-31 109.5 0.0 2.2e-31 109.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) SnoaL_4 PF13577.6 KXL46710.1 - 2.3e-26 92.4 0.0 3.2e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain RPE65 PF03055.15 KXL46711.1 - 1.9e-103 347.2 0.0 2.2e-103 346.9 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DDE_1 PF03184.19 KXL46712.1 - 3e-19 69.3 0.0 4.9e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease PPV_E2_C PF00511.17 KXL46712.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 E2 (early) protein, C terminal Y1_Tnp PF01797.16 KXL46712.1 - 0.15 12.2 0.1 0.28 11.3 0.1 1.3 1 0 0 1 1 1 0 Transposase IS200 like HTH_Tnp_Tc5 PF03221.16 KXL46713.1 - 0.043 13.9 0.2 0.048 13.7 0.2 1.2 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain Na_H_Exchanger PF00999.21 KXL46714.1 - 5.4e-23 81.4 33.7 5.9e-20 71.4 20.7 3.1 3 0 0 3 3 3 3 Sodium/hydrogen exchanger family FAD_binding_3 PF01494.19 KXL46715.1 - 1.6e-23 83.5 0.2 7.3e-19 68.2 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KXL46715.1 - 8.2e-10 38.8 0.1 3.3e-05 23.6 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXL46715.1 - 5e-07 29.3 0.1 9.5e-05 21.8 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXL46715.1 - 1e-05 26.0 0.3 4.3e-05 24.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXL46715.1 - 4e-05 22.9 0.3 0.0049 16.0 0.0 2.5 2 1 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 KXL46715.1 - 0.00011 22.3 0.1 0.00028 21.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KXL46715.1 - 0.00062 18.7 0.3 0.48 9.2 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase ApbA PF02558.16 KXL46715.1 - 0.00066 19.3 0.1 0.0012 18.5 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 KXL46715.1 - 0.024 13.4 0.0 0.24 10.0 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein AlaDh_PNT_C PF01262.21 KXL46715.1 - 0.026 13.8 0.1 0.05 12.9 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KXL46715.1 - 0.028 13.5 0.0 0.053 12.6 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 KXL46715.1 - 0.047 12.9 0.0 0.076 12.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 KXL46715.1 - 0.071 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 KXL46715.1 - 0.16 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF1188 PF06690.11 KXL46715.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) TrkA_N PF02254.18 KXL46715.1 - 0.2 11.9 0.1 0.44 10.8 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain bZIP_1 PF00170.21 KXL46716.1 - 1.1e-05 25.5 9.0 1.7e-05 24.8 9.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXL46716.1 - 0.027 14.6 9.3 0.06 13.4 9.3 1.6 1 0 0 1 1 1 0 Basic region leucine zipper Stm1_N PF09598.10 KXL46717.1 - 3.1e-16 60.0 1.4 3.1e-16 60.0 1.4 3.9 4 2 0 4 4 4 1 Stm1 HABP4_PAI-RBP1 PF04774.15 KXL46717.1 - 1.6e-06 28.9 6.3 1.6e-06 28.9 6.3 2.2 3 0 0 3 3 3 1 Hyaluronan / mRNA binding family Nucleoside_tran PF01733.18 KXL46719.1 - 0.00055 19.4 0.1 0.0007 19.1 0.1 1.1 1 0 0 1 1 1 1 Nucleoside transporter Tetraspanin PF00335.20 KXL46719.1 - 6.2 6.5 7.6 76 2.9 7.6 2.1 1 1 0 1 1 1 0 Tetraspanin family F-box-like PF12937.7 KXL46720.1 - 6.4e-05 22.8 0.2 0.00016 21.5 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXL46720.1 - 0.00076 19.3 0.1 0.00076 19.3 0.1 2.1 2 0 0 2 2 2 1 F-box domain Mito_fiss_reg PF05308.11 KXL46721.1 - 6.7 6.7 5.9 5.8 6.9 2.4 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator Sec61_beta PF03911.16 KXL46723.1 - 4.5e-17 61.8 1.2 5.9e-17 61.4 1.2 1.2 1 0 0 1 1 1 1 Sec61beta family Aldo_ket_red PF00248.21 KXL46724.1 - 5e-45 154.0 0.0 6e-45 153.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Chlorosome_CsmC PF11098.8 KXL46725.1 - 0.00012 22.0 3.7 0.00015 21.8 3.7 1.2 1 0 0 1 1 1 1 Chlorosome envelope protein C FAM199X PF15814.5 KXL46725.1 - 1.1 8.2 4.9 1.1 8.2 4.9 1.0 1 0 0 1 1 1 0 Protein family FAM199X SUR7 PF06687.12 KXL46726.1 - 1.3 8.6 9.4 1.3 8.6 1.2 2.8 2 1 1 3 3 3 0 SUR7/PalI family DUF485 PF04341.12 KXL46726.1 - 5.5 7.0 7.3 0.26 11.3 0.8 2.1 2 1 1 3 3 3 0 Protein of unknown function, DUF485 Mcp5_PH PF12814.7 KXL46727.1 - 3.2e-45 153.2 0.5 7.1e-45 152.1 0.5 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 KXL46727.1 - 0.00023 21.6 0.0 0.0006 20.3 0.0 1.7 1 0 0 1 1 1 1 PH domain VGPC1_C PF16799.5 KXL46727.1 - 0.2 11.7 6.1 0.14 12.1 0.3 3.2 3 0 0 3 3 3 0 C-terminal membrane-localisation domain of ion-channel, VCN1 DDE_1 PF03184.19 KXL46728.1 - 0.0025 17.5 0.0 0.0027 17.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Abhydrolase_6 PF12697.7 KXL46729.1 - 0.18 12.4 8.1 0.32 11.6 8.1 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family C1_2 PF03107.16 KXL46731.1 - 0.0016 18.7 9.5 0.002 18.4 9.5 1.1 1 0 0 1 1 1 1 C1 domain C1_1 PF00130.22 KXL46731.1 - 0.0074 16.2 11.1 0.028 14.3 0.7 2.0 1 1 1 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-B_box PF00643.24 KXL46731.1 - 0.69 10.1 12.0 0.39 10.9 9.7 1.8 2 1 0 2 2 2 0 B-box zinc finger PPR_3 PF13812.6 KXL46733.1 - 2.3e-10 40.4 3.9 0.32 11.1 0.2 6.7 4 3 3 7 7 7 4 Pentatricopeptide repeat domain PPR_2 PF13041.6 KXL46733.1 - 2.5e-10 40.4 1.1 0.35 11.1 0.0 7.9 8 2 2 10 10 10 2 PPR repeat family PPR PF01535.20 KXL46733.1 - 5.8e-08 32.5 0.0 0.57 10.5 0.0 7.0 7 0 0 7 7 7 1 PPR repeat TPR_19 PF14559.6 KXL46733.1 - 5.8e-06 26.7 0.6 1.1 9.8 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat PPR_long PF17177.4 KXL46733.1 - 0.0002 20.8 1.7 0.012 15.0 0.0 2.9 4 0 0 4 4 4 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KXL46733.1 - 0.00038 20.1 1.3 4.3 7.1 0.0 4.8 5 0 0 5 5 5 1 PPR repeat RecO_C PF02565.15 KXL46733.1 - 0.042 13.6 0.0 0.17 11.7 0.0 2.0 1 0 0 1 1 1 0 Recombination protein O C terminal DUF5305 PF17231.2 KXL46734.1 - 0.045 13.2 0.8 0.068 12.6 0.1 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5305) Glyco_transf_4 PF13439.6 KXL46734.1 - 0.35 10.9 2.1 0.65 10.0 0.0 2.3 3 0 0 3 3 3 0 Glycosyltransferase Family 4 LSM PF01423.22 KXL46735.1 - 1.9e-17 62.7 0.0 2.9e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXL46735.1 - 0.0021 18.2 0.0 0.0027 17.8 0.0 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain RAM PF15320.6 KXL46735.1 - 0.18 12.5 8.5 0.25 11.9 8.5 1.2 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein DUF4210 PF13915.6 KXL46736.1 - 6.8e-33 113.1 0.1 6.8e-33 113.1 0.1 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 KXL46736.1 - 1.3e-23 82.9 0.6 4e-23 81.3 0.6 2.0 1 0 0 1 1 1 1 Chromosome segregation during meiosis rRNA_processing PF08524.11 KXL46737.1 - 0.013 15.5 29.1 0.37 10.8 29.1 2.2 1 1 0 1 1 1 0 rRNA processing 2OG-FeII_Oxy_3 PF13640.6 KXL46739.1 - 8.1e-08 33.1 0.0 1.8e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.18 KXL46740.1 - 1.3e-23 83.4 2.6 1.8e-23 82.9 2.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL46740.1 - 0.013 15.6 0.9 0.022 14.8 0.9 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4680 PF15730.5 KXL46740.1 - 0.22 11.9 2.9 3.4 8.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4680) adh_short PF00106.25 KXL46741.1 - 7e-47 159.4 0.0 9.2e-47 159.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL46741.1 - 6.1e-34 117.6 0.0 7.9e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL46741.1 - 6.5e-06 26.2 0.0 1.2e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXL46741.1 - 2.3e-05 24.4 0.0 3.4e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXL46741.1 - 0.00011 21.7 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXL46741.1 - 0.0019 17.4 0.0 0.0034 16.5 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KXL46741.1 - 0.082 12.3 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Pirin PF02678.16 KXL46742.1 - 1.3e-27 95.9 0.6 2.7e-27 94.9 0.6 1.5 1 0 0 1 1 1 1 Pirin Pirin_C_2 PF17954.1 KXL46742.1 - 5.3e-09 36.1 0.0 6e-08 32.7 0.0 2.5 2 1 0 2 2 2 1 Quercetinase C-terminal cupin domain Cupin_2 PF07883.11 KXL46742.1 - 0.00063 19.4 2.5 0.0013 18.4 0.3 2.5 3 0 0 3 3 3 1 Cupin domain CorA PF01544.18 KXL46743.1 - 2.1e-06 27.3 1.6 2.1e-06 27.3 1.6 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein EMP70 PF02990.16 KXL46743.1 - 0.0031 16.3 1.6 0.0044 15.8 1.6 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 TauD PF02668.16 KXL46744.1 - 2.7e-33 115.9 0.0 3.8e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sirohm_synth_C PF14823.6 KXL46744.1 - 0.13 11.9 0.8 0.25 11.0 0.2 1.8 2 0 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal dsrm PF00035.26 KXL46746.1 - 1.4e-07 32.1 0.0 2.7e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 KXL46746.1 - 0.00076 19.6 0.0 0.24 11.5 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KXL46746.1 - 0.016 15.9 0.4 0.28 11.8 0.4 2.4 1 1 0 1 1 1 0 Ribonuclease III domain RCDG1 PF15725.5 KXL46746.1 - 1 9.9 7.7 3.6 8.1 7.7 1.9 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein FOXP-CC PF16159.5 KXL46747.1 - 0.53 11.0 5.8 1.3 9.7 0.6 2.8 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KXL46747.1 - 3.9 8.6 16.3 0.35 11.8 2.6 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger Mito_fiss_reg PF05308.11 KXL46748.1 - 0.45 10.5 4.2 0.43 10.6 4.2 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 KXL46748.1 - 0.47 10.5 8.4 0.52 10.3 8.4 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 KXL46748.1 - 0.89 9.0 6.6 0.87 9.0 6.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal EF-hand_7 PF13499.6 KXL46749.1 - 4.8e-11 43.0 0.6 4e-07 30.4 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 KXL46749.1 - 2.7e-09 37.2 0.0 0.00014 22.1 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.6 KXL46749.1 - 4.3e-08 32.5 0.4 0.019 14.9 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KXL46749.1 - 1.3e-07 30.6 0.1 0.026 14.0 0.0 3.5 3 1 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KXL46749.1 - 3.7e-06 26.7 0.1 0.00012 21.9 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain pair Thioredoxin_3 PF13192.6 KXL46749.1 - 0.078 13.0 0.0 0.19 11.8 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin domain DUF3216 PF11505.8 KXL46749.1 - 0.11 12.8 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) HIT PF01230.23 KXL46750.1 - 4.9e-22 78.5 0.0 7.6e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KXL46750.1 - 0.0003 21.2 0.0 0.00042 20.8 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KXL46750.1 - 0.055 13.3 0.0 0.081 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 adh_short PF00106.25 KXL46751.1 - 5.2e-23 81.5 0.0 3.2e-18 65.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXL46751.1 - 2.9e-12 46.7 0.0 1.1e-10 41.4 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL46751.1 - 1.4e-08 34.9 0.0 2.1e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL46751.1 - 0.11 11.9 0.0 0.25 10.8 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXL46751.1 - 0.22 10.6 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_11 PF08241.12 KXL46752.1 - 6.1e-19 68.5 0.0 1e-18 67.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL46752.1 - 2.2e-18 66.7 0.0 3.9e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL46752.1 - 4.7e-14 52.9 0.0 8.5e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL46752.1 - 8.7e-13 48.3 0.0 1.3e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXL46752.1 - 5e-09 36.2 0.0 7.5e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 KXL46752.1 - 0.0012 18.0 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase PrmA PF06325.13 KXL46752.1 - 0.0024 17.3 0.0 0.058 12.8 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) tRNA_U5-meth_tr PF05958.11 KXL46752.1 - 0.029 13.4 0.0 0.06 12.3 0.0 1.4 2 0 0 2 2 2 0 tRNA (Uracil-5-)-methyltransferase NodS PF05401.11 KXL46752.1 - 0.11 12.1 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) MTS PF05175.14 KXL46752.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.20 KXL46752.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 KXL46752.1 - 0.18 11.9 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DPBB_1 PF03330.18 KXL46753.1 - 1.8e-05 24.9 0.0 3.5e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Lytic transglycolase CoA_binding_2 PF13380.6 KXL46757.1 - 1e-24 87.2 0.0 1.2e-24 87.0 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain Amidohydro_2 PF04909.14 KXL46760.1 - 1.5e-27 97.2 0.1 8.7e-27 94.6 0.1 1.9 1 1 0 1 1 1 1 Amidohydrolase CDC73_C PF05179.14 KXL46761.1 - 1.1e-55 187.6 0.0 1.9e-55 186.8 0.0 1.4 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal SMP PF04927.12 KXL46761.1 - 0.0043 17.5 1.7 0.012 16.1 1.7 1.7 1 0 0 1 1 1 1 Seed maturation protein PAS_3 PF08447.12 KXL46762.1 - 4.5e-07 30.1 0.0 7.8e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 KXL46762.1 - 5.9e-07 29.7 0.0 1.3e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 KXL46762.1 - 8.8e-05 22.7 0.1 0.18 12.1 0.0 2.9 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 KXL46762.1 - 0.00016 21.6 0.0 0.002 18.1 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.6 KXL46762.1 - 0.065 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 PAS domain WD40 PF00400.32 KXL46763.1 - 1.3e-16 60.6 3.4 1.8e-06 28.6 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat PD40 PF07676.12 KXL46763.1 - 0.032 14.2 0.1 0.093 12.7 0.1 1.8 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat AA_kinase PF00696.28 KXL46764.1 - 2.2e-38 132.2 1.0 3.1e-38 131.8 1.0 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 KXL46764.1 - 1.2e-15 57.2 0.4 2.8e-15 56.0 0.1 1.8 2 0 0 2 2 2 1 PUA domain TIP41 PF04176.13 KXL46765.1 - 1.4e-65 220.0 0.5 1.8e-65 219.7 0.5 1.1 1 0 0 1 1 1 1 TIP41-like family MIB_HERC2 PF06701.13 KXL46765.1 - 0.072 13.3 1.5 0.14 12.4 0.3 2.0 2 0 0 2 2 2 0 Mib_herc2 FAD_binding_2 PF00890.24 KXL46766.1 - 1.3e-117 393.5 2.8 1.8e-117 393.0 2.8 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KXL46766.1 - 2.8e-40 137.3 3.0 4.5e-40 136.6 3.0 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 KXL46766.1 - 2.2e-06 27.2 0.3 0.0014 17.9 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXL46766.1 - 0.00011 21.5 1.5 0.022 13.9 2.7 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 KXL46766.1 - 0.0026 17.1 0.5 0.094 11.9 0.1 2.5 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 KXL46766.1 - 0.0032 16.8 0.5 0.0061 15.9 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXL46766.1 - 0.031 13.0 0.6 0.14 10.8 0.2 2.2 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.24 KXL46766.1 - 0.032 13.8 0.2 0.068 12.7 0.2 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase I_LWEQ PF01608.17 KXL46766.1 - 0.13 12.5 0.5 0.27 11.5 0.1 1.6 2 0 0 2 2 2 0 I/LWEQ domain Pyr_redox_3 PF13738.6 KXL46766.1 - 1.6 7.9 3.0 1.9 7.6 1.7 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HIGH_NTase1_ass PF16581.5 KXL46767.1 - 0.27 11.2 0.0 0.43 10.5 0.0 1.2 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Collagen PF01391.18 KXL46767.1 - 1 9.1 12.5 0.084 12.6 7.0 2.1 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Glyco_hydro_6 PF01341.17 KXL46768.1 - 2.8e-90 303.1 0.5 1.3e-89 300.9 0.5 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 6 PI3K_P85_iSH2 PF16454.5 KXL46769.1 - 0.0045 16.6 0.1 0.023 14.3 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain BLOC1_2 PF10046.9 KXL46769.1 - 0.03 14.6 0.1 0.064 13.6 0.1 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1757 PF08560.10 KXL46770.1 - 0.017 15.2 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1757) PhoD PF09423.10 KXL46770.1 - 0.078 12.0 0.0 0.092 11.7 0.0 1.1 1 0 0 1 1 1 0 PhoD-like phosphatase DUF1254 PF06863.12 KXL46771.1 - 4.2e-25 88.4 0.1 8.2e-25 87.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1254) DUF1214 PF06742.11 KXL46771.1 - 4.9e-19 68.8 0.0 1.4e-18 67.3 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1214) BRO1 PF03097.18 KXL46772.1 - 2.9e-135 451.1 2.7 2.9e-135 451.1 2.7 2.6 2 1 1 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KXL46772.1 - 4.3e-77 259.3 13.6 4.3e-77 259.3 13.6 1.7 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Unstab_antitox PF09720.10 KXL46772.1 - 0.091 12.8 0.3 30 4.8 0.2 3.2 2 0 0 2 2 2 0 Putative addiction module component DSBA PF01323.20 KXL46772.1 - 0.14 12.0 0.7 0.36 10.6 0.7 1.7 1 0 0 1 1 1 0 DSBA-like thioredoxin domain DUF835 PF05763.12 KXL46772.1 - 0.23 11.2 0.8 0.46 10.2 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF835) DUF416 PF04222.12 KXL46772.1 - 0.32 10.4 4.2 0.37 10.2 0.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF416) Pex19 PF04614.12 KXL46772.1 - 7.1 6.3 8.9 12 5.6 7.2 2.2 2 1 0 2 2 2 0 Pex19 protein family DnaJ_C PF01556.18 KXL46773.1 - 7.1e-37 126.8 0.0 1e-36 126.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KXL46773.1 - 1.1e-22 79.9 2.7 2.2e-22 78.9 2.7 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KXL46773.1 - 1.3e-07 31.9 23.0 2.7e-07 30.8 23.0 1.6 1 0 0 1 1 1 1 DnaJ central domain 5-FTHF_cyc-lig PF01812.20 KXL46774.1 - 1.4e-35 122.9 0.0 2.9e-35 121.8 0.0 1.5 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Rot1 PF10681.9 KXL46775.1 - 3.3e-93 311.0 0.1 3.8e-93 310.8 0.1 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Sugar_tr PF00083.24 KXL46777.1 - 1.4e-111 373.6 19.6 1.6e-111 373.3 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL46777.1 - 9.2e-25 87.3 46.0 1.5e-17 63.6 13.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXL46777.1 - 0.00024 19.7 1.7 0.00024 19.7 1.7 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) UNC-93 PF05978.16 KXL46777.1 - 0.00026 20.7 0.8 0.00026 20.7 0.8 2.8 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 DUF1735 PF08522.10 KXL46778.1 - 0.013 16.1 0.1 0.014 16.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1735) TAP_C PF03943.13 KXL46781.1 - 9.6e-16 57.2 0.5 1.9e-15 56.2 0.5 1.5 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.7 KXL46781.1 - 7e-07 29.5 4.7 2.8e-05 24.4 1.8 2.6 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KXL46781.1 - 3.4e-06 26.7 0.4 7e-06 25.7 0.4 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 KXL46781.1 - 0.00011 21.9 2.2 0.00035 20.3 2.2 1.9 1 0 0 1 1 1 1 Leucine rich repeat NTF2 PF02136.20 KXL46781.1 - 0.0013 19.2 0.1 0.0078 16.8 0.1 2.2 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_1 PF00560.33 KXL46781.1 - 0.018 15.5 1.7 3.1 8.7 0.0 3.2 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_6 PF13516.6 KXL46781.1 - 0.077 13.1 5.7 12 6.3 0.3 4.1 4 0 0 4 4 4 0 Leucine Rich repeat P3A PF08727.11 KXL46782.1 - 0.11 11.9 0.0 0.27 10.6 0.0 1.6 1 0 0 1 1 1 0 Poliovirus 3A protein like Acetyltransf_1 PF00583.25 KXL46783.1 - 8.6e-13 48.5 0.0 1e-12 48.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXL46783.1 - 1.3e-08 35.1 0.0 1.7e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXL46783.1 - 2.2e-08 34.1 0.0 3e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXL46783.1 - 4.1e-08 33.1 0.0 6.4e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KXL46783.1 - 0.00031 21.4 0.0 0.00032 21.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXL46783.1 - 0.22 11.7 0.0 0.35 11.0 0.0 1.2 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Phos_pyr_kin PF08543.12 KXL46785.1 - 4.7e-13 49.1 0.0 7.4e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KXL46785.1 - 0.0003 20.2 0.0 0.0016 17.8 0.0 1.9 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Peptidase_S8 PF00082.22 KXL46787.1 - 5.6e-33 114.5 3.8 9.2e-33 113.8 3.8 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KXL46787.1 - 3.4e-29 100.7 0.9 7.2e-29 99.6 0.9 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain DUF4131 PF13567.6 KXL46787.1 - 8.7 6.0 7.6 26 4.4 2.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) PhoD PF09423.10 KXL46788.1 - 7.7e-06 25.2 0.0 9.7e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase Beta-lactamase PF00144.24 KXL46789.1 - 4.5e-14 52.4 0.0 5.2e-14 52.2 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Ribosomal_L12 PF00542.19 KXL46790.1 - 1.1e-19 70.5 4.4 7.7e-19 67.8 3.5 2.1 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KXL46790.1 - 1.5e-11 43.8 2.5 2e-11 43.4 0.1 2.4 3 0 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain SpoVIF PF14069.6 KXL46790.1 - 0.087 12.6 0.4 0.25 11.1 0.1 1.9 2 1 0 2 2 2 0 Stage VI sporulation protein F AAA_5 PF07728.14 KXL46791.1 - 7.6e-128 421.2 2.7 3.6e-23 82.1 0.0 9.7 8 1 1 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KXL46791.1 - 6.5e-49 164.5 5.8 1e-18 67.4 0.0 6.4 5 0 0 5 5 5 3 Midasin AAA lid domain AAA_3 PF07726.11 KXL46791.1 - 1.8e-30 105.5 0.0 3.2e-09 36.7 0.0 8.0 8 0 0 8 8 8 3 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KXL46791.1 - 1e-29 103.4 0.6 9.6e-05 22.0 0.0 7.4 7 0 0 7 7 6 6 P-loop containing dynein motor region AAA_16 PF13191.6 KXL46791.1 - 3e-29 102.6 11.8 0.00016 22.1 0.1 8.0 6 1 1 7 7 7 6 AAA ATPase domain AAA PF00004.29 KXL46791.1 - 5e-29 101.4 2.0 0.0006 20.2 0.0 7.5 7 0 0 7 7 6 6 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 KXL46791.1 - 1.3e-28 99.1 1.5 2.6e-27 95.0 0.0 3.8 4 0 0 4 4 2 1 Midasin AAA lid domain Dynein_heavy PF03028.15 KXL46791.1 - 1.5e-25 89.6 0.0 0.0036 17.4 0.0 8.9 8 1 0 8 8 8 4 Dynein heavy chain region D6 P-loop domain AAA_22 PF13401.6 KXL46791.1 - 1.6e-22 80.3 0.9 0.0065 16.8 0.0 7.4 6 0 0 6 6 6 4 AAA domain AAA_18 PF13238.6 KXL46791.1 - 1.6e-22 80.4 1.6 0.0057 17.2 0.0 7.8 6 1 0 7 7 6 5 AAA domain AAA_33 PF13671.6 KXL46791.1 - 8.9e-20 71.3 0.8 0.0018 18.5 0.1 7.0 6 0 0 6 6 6 3 AAA domain AAA_6 PF12774.7 KXL46791.1 - 3.4e-19 69.0 0.2 0.08 11.9 0.0 7.9 8 0 0 8 8 7 6 Hydrolytic ATP binding site of dynein motor region ABC_tran PF00005.27 KXL46791.1 - 9.1e-19 68.3 1.2 0.0037 17.8 0.1 7.4 6 0 0 6 6 6 4 ABC transporter Sigma54_activat PF00158.26 KXL46791.1 - 1.4e-18 67.2 0.0 0.028 14.1 0.0 6.8 6 0 0 6 6 6 4 Sigma-54 interaction domain TsaE PF02367.17 KXL46791.1 - 1.5e-18 67.0 3.4 0.014 15.4 0.0 6.7 6 0 0 6 6 6 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KXL46791.1 - 5.1e-18 65.4 0.0 0.0034 17.4 0.0 8.7 9 0 0 9 9 7 2 AAA domain Sigma54_activ_2 PF14532.6 KXL46791.1 - 2.7e-16 59.9 0.8 0.0096 16.0 0.0 7.0 6 0 0 6 6 6 2 Sigma-54 interaction domain RNA_helicase PF00910.22 KXL46791.1 - 6.2e-16 58.7 0.6 0.16 12.4 0.0 6.9 6 0 0 6 6 6 1 RNA helicase AAA_30 PF13604.6 KXL46791.1 - 1.3e-15 57.6 6.2 0.2 11.3 0.0 9.1 7 2 0 7 7 7 3 AAA domain RsgA_GTPase PF03193.16 KXL46791.1 - 6.5e-14 52.2 0.3 0.33 10.8 0.0 6.6 6 0 0 6 6 6 2 RsgA GTPase T2SSE PF00437.20 KXL46791.1 - 6.6e-14 51.6 0.0 0.045 12.8 0.0 6.1 6 0 0 6 6 6 3 Type II/IV secretion system protein NACHT PF05729.12 KXL46791.1 - 4.1e-13 49.6 11.4 0.014 15.3 0.0 7.2 7 0 0 7 7 6 3 NACHT domain Zeta_toxin PF06414.12 KXL46791.1 - 4.8e-13 48.8 1.3 0.0078 15.5 0.0 6.9 6 0 0 6 6 6 2 Zeta toxin AAA_28 PF13521.6 KXL46791.1 - 5.4e-13 49.5 7.6 0.17 12.2 0.0 7.1 7 0 0 7 7 6 3 AAA domain RuvB_N PF05496.12 KXL46791.1 - 2e-11 43.9 4.7 1 9.1 0.0 6.9 7 0 0 7 7 6 2 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KXL46791.1 - 2.6e-11 43.3 1.9 2.6 7.3 0.0 8.8 9 0 0 9 9 8 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 KXL46791.1 - 2.8e-11 43.0 0.9 0.87 9.4 0.0 6.7 6 0 0 6 6 6 2 P-loop containing region of AAA domain AAA_19 PF13245.6 KXL46791.1 - 1e-10 42.1 7.3 0.061 13.7 0.1 7.6 8 0 0 8 8 6 1 AAA domain Rad17 PF03215.15 KXL46791.1 - 6.7e-10 39.2 2.5 0.19 11.6 0.0 6.6 7 0 0 7 7 6 2 Rad17 P-loop domain AAA_25 PF13481.6 KXL46791.1 - 1.3e-09 37.9 3.8 2.4 7.7 0.0 6.4 6 0 0 6 6 5 0 AAA domain IstB_IS21 PF01695.17 KXL46791.1 - 1.5e-09 37.8 0.1 0.48 10.1 0.0 6.6 6 0 0 6 6 6 1 IstB-like ATP binding protein PduV-EutP PF10662.9 KXL46791.1 - 2.4e-09 37.1 2.4 0.2 11.4 0.1 5.9 6 0 0 6 6 6 2 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 KXL46791.1 - 1.2e-08 35.7 6.6 0.83 10.1 0.0 7.6 8 0 0 8 8 6 1 AAA domain Roc PF08477.13 KXL46791.1 - 1.3e-08 35.0 2.6 0.86 9.8 0.0 6.6 6 0 0 6 6 6 1 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 KXL46791.1 - 1.6e-08 34.7 0.0 0.47 10.3 0.0 5.9 6 0 0 6 6 5 2 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 KXL46791.1 - 3.2e-08 33.6 0.5 22 5.2 0.0 6.7 6 0 0 6 6 6 0 50S ribosome-binding GTPase AAA_24 PF13479.6 KXL46791.1 - 1.4e-07 31.5 0.0 3.2 7.4 0.0 6.1 6 0 0 6 6 6 0 AAA domain DUF815 PF05673.13 KXL46791.1 - 1.9e-07 30.5 0.6 2 7.5 0.0 6.4 7 0 0 7 7 6 1 Protein of unknown function (DUF815) SRP54 PF00448.22 KXL46791.1 - 2.6e-07 30.5 9.4 1 9.0 0.0 6.0 6 0 0 6 6 5 1 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 KXL46791.1 - 9.6e-07 28.9 9.0 0.016 15.1 0.1 6.0 6 0 0 6 6 5 1 NTPase TniB PF05621.11 KXL46791.1 - 9.7e-07 28.4 0.1 2.8 7.3 0.0 5.6 5 0 0 5 5 5 0 Bacterial TniB protein cobW PF02492.19 KXL46791.1 - 4e-06 26.5 9.0 0.027 14.1 0.0 5.7 6 0 0 6 6 6 2 CobW/HypB/UreG, nucleotide-binding domain MCM PF00493.23 KXL46791.1 - 8.9e-06 25.0 0.0 0.022 13.9 0.0 5.0 7 0 0 7 7 5 1 MCM P-loop domain AAA_17 PF13207.6 KXL46791.1 - 1.7e-05 25.3 5.5 2.1 8.8 0.1 5.9 6 0 0 6 6 5 1 AAA domain TIP49 PF06068.13 KXL46791.1 - 2.1e-05 23.9 1.1 1.8 7.7 0.0 5.7 6 0 0 6 6 6 1 TIP49 P-loop domain Bac_DnaA PF00308.18 KXL46791.1 - 2.2e-05 24.4 0.2 4.2 7.1 0.0 5.5 5 0 0 5 5 5 0 Bacterial dnaA protein KAP_NTPase PF07693.14 KXL46791.1 - 2.4e-05 23.8 0.0 19 4.4 0.0 5.1 5 0 0 5 5 5 0 KAP family P-loop domain Viral_helicase1 PF01443.18 KXL46791.1 - 4.5e-05 23.3 0.5 2.1 8.1 0.0 5.7 6 0 0 6 6 6 1 Viral (Superfamily 1) RNA helicase G-alpha PF00503.20 KXL46791.1 - 6.7e-05 22.2 7.8 1.4 8.0 0.0 5.8 6 0 0 6 6 6 1 G-protein alpha subunit ResIII PF04851.15 KXL46791.1 - 0.00017 21.7 2.9 1.7 8.6 0.0 5.6 6 0 0 6 6 5 1 Type III restriction enzyme, res subunit SRPRB PF09439.10 KXL46791.1 - 0.00017 21.0 1.6 5.2 6.5 0.0 5.2 6 0 0 6 6 4 0 Signal recognition particle receptor beta subunit dNK PF01712.19 KXL46791.1 - 0.00038 20.4 6.9 8.3 6.2 0.0 6.2 6 0 0 6 6 6 0 Deoxynucleoside kinase ATPase PF06745.13 KXL46791.1 - 0.00039 19.8 0.7 9.4 5.5 0.0 4.7 5 0 0 5 5 4 0 KaiC NB-ARC PF00931.22 KXL46791.1 - 0.00075 18.8 1.3 5.7 6.0 0.0 5.5 6 0 0 6 6 5 0 NB-ARC domain FtsK_SpoIIIE PF01580.18 KXL46791.1 - 0.00088 18.7 1.0 2.9 7.2 0.0 4.6 5 0 0 5 5 4 0 FtsK/SpoIIIE family VWA PF00092.28 KXL46791.1 - 0.00088 19.6 0.2 0.0024 18.1 0.2 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain CPT PF07931.12 KXL46791.1 - 0.001 18.9 3.0 7.4 6.4 0.0 5.8 6 1 0 6 6 4 0 Chloramphenicol phosphotransferase-like protein Dynamin_N PF00350.23 KXL46791.1 - 0.0012 18.9 0.1 3.6 7.6 0.0 4.2 3 0 0 3 3 3 0 Dynamin family DEAD PF00270.29 KXL46791.1 - 0.0014 18.5 0.4 12 5.7 0.0 4.6 5 0 0 5 5 3 0 DEAD/DEAH box helicase Pox_A32 PF04665.12 KXL46791.1 - 0.0016 18.0 0.1 0.81 9.1 0.0 4.3 5 0 0 5 5 4 1 Poxvirus A32 protein PRK PF00485.18 KXL46791.1 - 0.0034 17.2 0.3 6.8 6.4 0.0 3.9 4 0 0 4 4 3 0 Phosphoribulokinase / Uridine kinase family Septin PF00735.18 KXL46791.1 - 0.005 16.2 2.3 33 3.6 0.0 5.6 6 0 0 6 6 6 0 Septin PhoH PF02562.16 KXL46791.1 - 0.0068 15.9 1.0 14 5.0 0.0 4.9 5 0 0 5 5 5 0 PhoH-like protein KTI12 PF08433.10 KXL46791.1 - 0.0087 15.5 0.3 0.24 10.8 0.0 3.3 3 0 0 3 3 2 1 Chromatin associated protein KTI12 AAA_8 PF12780.7 KXL46791.1 - 0.009 15.4 1.7 7.3 5.8 0.0 4.8 4 0 0 4 4 3 0 P-loop containing dynein motor region D4 FeoB_N PF02421.18 KXL46791.1 - 0.022 14.3 1.9 24 4.4 0.0 4.7 5 0 0 5 5 4 0 Ferrous iron transport protein B VWA_2 PF13519.6 KXL46791.1 - 0.022 15.4 1.2 0.083 13.6 0.1 2.7 2 0 0 2 2 1 0 von Willebrand factor type A domain DnaB_C PF03796.15 KXL46791.1 - 0.023 14.0 5.1 10 5.4 0.0 4.8 4 0 0 4 4 4 0 DnaB-like helicase C terminal domain MeaB PF03308.16 KXL46791.1 - 0.032 13.2 2.2 3.3 6.6 0.1 4.0 4 0 0 4 4 4 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 KXL46791.1 - 0.064 13.2 8.6 5 7.0 0.0 5.6 6 0 0 6 6 6 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2075 PF09848.9 KXL46791.1 - 0.093 12.0 2.9 8.5 5.5 0.0 4.2 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2075) ATP_bind_1 PF03029.17 KXL46791.1 - 0.095 12.5 8.3 5.9 6.6 0.0 5.5 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein Ploopntkinase3 PF18751.1 KXL46791.1 - 0.12 12.3 1.0 11 5.9 0.0 3.9 5 0 0 5 5 4 0 P-loop Nucleotide Kinase3 APS_kinase PF01583.20 KXL46791.1 - 0.12 12.2 1.3 4.9 7.0 0.0 3.9 4 0 0 4 4 3 0 Adenylylsulphate kinase Cytidylate_kin PF02224.18 KXL46791.1 - 0.13 11.9 0.7 19 4.9 0.0 4.1 4 0 0 4 4 4 0 Cytidylate kinase IPT PF01745.16 KXL46791.1 - 0.15 11.5 0.9 5.4 6.3 0.0 3.5 4 0 0 4 4 3 0 Isopentenyl transferase SKI PF01202.22 KXL46791.1 - 0.16 12.1 2.0 51 4.0 0.0 4.3 4 0 0 4 4 3 0 Shikimate kinase AAA_21 PF13304.6 KXL46791.1 - 0.17 11.6 1.9 1.5 8.6 0.1 3.6 5 0 0 5 5 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DAP3 PF10236.9 KXL46791.1 - 0.21 10.7 3.8 3 6.9 0.0 4.0 5 0 0 5 5 4 0 Mitochondrial ribosomal death-associated protein 3 DUF87 PF01935.17 KXL46791.1 - 0.57 10.2 9.9 0.95 9.5 0.0 5.6 6 0 0 6 6 5 0 Helicase HerA, central domain Ras PF00071.22 KXL46791.1 - 1.2 8.8 2.9 70 3.0 0.0 4.4 5 0 0 5 5 3 0 Ras family CbiA PF01656.23 KXL46791.1 - 3.8 7.6 10.3 39 4.3 0.0 5.4 5 0 0 5 5 5 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF805 PF05656.14 KXL46792.1 - 5.2 7.5 11.3 1.8 9.0 0.6 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF805) Sulfotransfer_4 PF17784.1 KXL46794.1 - 3.7e-47 160.9 0.2 4.8e-47 160.6 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXL46794.1 - 1.6e-07 32.0 0.2 0.00021 21.8 0.0 2.2 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 KXL46794.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Sulfotransferase domain GTP_EFTU PF00009.27 KXL46795.1 - 1.1e-40 139.3 0.0 1.6e-40 138.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KXL46795.1 - 3.2e-24 84.8 0.0 8.6e-24 83.4 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KXL46795.1 - 1.2e-16 60.5 0.1 1.7e-08 34.3 0.0 2.5 1 1 1 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KXL46795.1 - 6.1e-08 32.9 0.0 2.5e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 KXL46795.1 - 7.2e-08 32.2 0.0 0.0063 16.3 0.0 2.7 2 0 0 2 2 2 2 Elongation factor G, domain IV RF3_C PF16658.5 KXL46795.1 - 0.0073 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Vps5 PF09325.10 KXL46796.1 - 6.6e-13 48.8 5.0 1.2e-12 47.9 5.0 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KXL46796.1 - 9.1e-10 38.5 0.0 1.8e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 PX domain CENP-H PF05837.12 KXL46796.1 - 1.7 9.1 9.3 3.7 8.0 7.0 2.5 2 0 0 2 2 2 0 Centromere protein H (CENP-H) NST1 PF13945.6 KXL46796.1 - 3.1 7.9 11.2 0.75 9.9 3.0 2.3 2 0 0 2 2 2 0 Salt tolerance down-regulator Voltage_CLC PF00654.20 KXL46799.1 - 1.2e-90 304.3 26.5 1.8e-90 303.7 26.5 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 KXL46799.1 - 1.7e-06 28.4 0.0 0.0019 18.6 0.0 2.6 2 0 0 2 2 2 2 CBS domain MFS_1 PF07690.16 KXL46800.1 - 2.7e-44 151.6 49.8 2.7e-44 151.6 49.8 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily RAI16-like PF10257.9 KXL46801.1 - 1.1e-66 225.2 0.1 1.6e-66 224.6 0.1 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein ADP_ribosyl_GH PF03747.14 KXL46801.1 - 0.29 10.8 0.9 0.55 9.9 0.9 1.3 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase EST1_DNA_bind PF10373.9 KXL46802.1 - 8.4e-07 28.7 0.0 2.5e-05 23.9 0.0 2.3 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain PX PF00787.24 KXL46803.1 - 3.4e-17 62.5 0.0 6.3e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 PX domain P5CR_dimer PF14748.6 KXL46804.1 - 8.6e-32 109.5 3.2 1.8e-31 108.5 3.2 1.6 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KXL46804.1 - 1.6e-09 38.2 1.8 9.2e-08 32.6 0.0 3.1 5 0 0 5 5 5 1 NADP oxidoreductase coenzyme F420-dependent E1_dh PF00676.20 KXL46805.1 - 1.3e-112 375.6 0.3 1.6e-112 375.3 0.3 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KXL46805.1 - 0.00058 19.2 0.3 0.00094 18.5 0.3 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase adh_short PF00106.25 KXL46808.1 - 5.3e-19 68.4 0.0 1.7e-14 53.8 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXL46808.1 - 2.2e-07 30.7 0.0 7.1e-06 25.7 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL46808.1 - 9.3e-07 28.9 0.2 1.4e-06 28.3 0.2 1.3 1 0 0 1 1 1 1 KR domain WD40 PF00400.32 KXL46809.1 - 1.2e-37 127.2 19.5 3e-07 31.0 0.1 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL46809.1 - 1.6e-09 37.9 0.1 0.12 12.7 0.0 5.3 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXL46809.1 - 5.6e-07 28.6 6.0 0.88 8.1 0.0 5.7 1 1 5 6 6 6 4 Nucleoporin Nup120/160 WD40_like PF17005.5 KXL46809.1 - 0.002 17.5 0.0 0.051 12.9 0.0 2.1 1 1 1 2 2 2 1 WD40-like domain PQQ_2 PF13360.6 KXL46809.1 - 0.013 15.1 4.1 0.034 13.7 4.1 1.7 1 1 0 1 1 1 0 PQQ-like domain PQQ_3 PF13570.6 KXL46809.1 - 0.055 14.0 10.4 10 6.8 0.1 4.8 3 2 2 5 5 5 0 PQQ-like domain DUF5046 PF16465.5 KXL46809.1 - 0.086 12.3 0.0 2.7 7.4 0.0 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF5046) Mito_carr PF00153.27 KXL46810.1 - 1.1e-45 153.4 4.7 1.9e-15 56.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Hat1_N PF10394.9 KXL46811.1 - 1.1e-43 149.2 0.0 2.6e-43 148.0 0.0 1.6 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus CLZ PF16526.5 KXL46811.1 - 0.12 12.8 1.3 0.27 11.6 1.3 1.6 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4890 PF16231.5 KXL46811.1 - 1.2 9.7 5.4 2.8 8.5 5.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4890) Zip PF02535.22 KXL46812.1 - 2.8e-32 112.3 24.6 5.7e-23 81.7 16.6 3.0 2 1 0 2 2 2 2 ZIP Zinc transporter HET PF06985.11 KXL46813.1 - 1.8e-32 112.7 5.8 4.8e-32 111.3 5.8 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ETF PF01012.21 KXL46814.1 - 6.2e-46 156.6 0.7 8.3e-46 156.2 0.7 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Aldedh PF00171.22 KXL46815.1 - 1.3e-161 538.2 2.6 1.5e-161 538.1 2.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3102 PF11300.8 KXL46815.1 - 0.069 13.4 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3102) DUF4604 PF15377.6 KXL46815.1 - 0.12 12.7 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Glyco_hydro_43 PF04616.14 KXL46816.1 - 9e-31 107.2 0.4 1.2e-30 106.9 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Cation_ATPase_C PF00689.21 KXL46817.1 - 2.3e-39 135.0 6.3 2.3e-39 135.0 6.3 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KXL46817.1 - 3.4e-37 127.7 7.4 1.7e-36 125.4 0.1 3.1 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase PF00702.26 KXL46817.1 - 1.7e-22 80.7 0.1 1e-10 42.3 0.1 3.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXL46817.1 - 4.5e-16 58.7 0.0 8.9e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KXL46817.1 - 9.9e-09 34.8 0.0 2.5e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXL46817.1 - 0.00026 20.8 0.5 0.0012 18.6 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXL46817.1 - 0.011 16.1 0.0 0.078 13.4 0.0 2.3 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF2807 PF10988.8 KXL46817.1 - 0.09 12.6 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain DUF2157 PF09925.9 KXL46817.1 - 3.7 7.3 8.3 1.1 9.1 0.1 3.0 4 0 0 4 4 4 0 Predicted membrane protein (DUF2157) DUF2428 PF10350.9 KXL46818.1 - 9.4e-52 176.0 0.1 4.9e-51 173.6 0.0 2.4 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) Tim17 PF02466.19 KXL46819.1 - 5e-28 97.7 3.7 7.5e-28 97.1 3.7 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family NIF PF03031.18 KXL46821.1 - 2.9e-55 186.3 0.1 3.4e-55 186.1 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Ribosomal_60s PF00428.19 KXL46822.1 - 0.44 11.2 2.6 0.64 10.6 2.6 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein CBM_21 PF03370.13 KXL46823.1 - 5.8e-35 119.9 0.4 9.1e-35 119.3 0.4 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KXL46823.1 - 5.8e-09 36.4 1.9 1.2e-08 35.5 1.9 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) BolA PF01722.18 KXL46825.1 - 8.9e-13 48.3 0.0 2.3e-12 47.0 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein Metallophos PF00149.28 KXL46826.1 - 7.9e-11 42.8 0.0 2e-10 41.5 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXL46826.1 - 2.2e-05 24.7 0.2 0.00011 22.4 0.1 1.9 1 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain PI3Ka PF00613.20 KXL46827.1 - 1.7e-54 184.1 0.3 2.7e-54 183.4 0.3 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KXL46827.1 - 1.1e-40 140.1 0.0 2e-37 129.4 0.0 2.7 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 KXL46827.1 - 2e-30 105.5 0.0 3.7e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 KXL46827.1 - 0.078 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Nse4_C PF08743.10 KXL46828.1 - 1.3e-32 111.9 0.0 6e-32 109.8 0.0 2.1 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 KXL46828.1 - 1.1e-17 63.8 2.6 7.3e-17 61.2 2.6 2.3 1 1 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE MgtE_N PF03448.17 KXL46829.1 - 0.14 12.8 0.0 0.2 12.3 0.0 1.2 1 0 0 1 1 1 0 MgtE intracellular N domain Zn_clus PF00172.18 KXL46830.1 - 3e-05 24.1 4.6 5.4e-05 23.2 4.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1203 PF06718.11 KXL46831.1 - 0.64 10.3 2.9 4.7 7.5 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1203) ECR1_N PF14382.6 KXL46831.1 - 1.5 8.6 17.2 29 4.5 0.1 6.5 7 0 0 7 7 7 0 Exosome complex exonuclease RRP4 N-terminal region bZIP_1 PF00170.21 KXL46832.1 - 0.0081 16.2 6.1 0.0081 16.2 6.1 1.5 2 0 0 2 2 2 1 bZIP transcription factor PspA_IM30 PF04012.12 KXL46832.1 - 0.0081 15.8 1.5 0.012 15.2 1.5 1.2 1 0 0 1 1 1 1 PspA/IM30 family Tropomyosin PF00261.20 KXL46832.1 - 0.013 14.9 2.0 0.019 14.3 2.0 1.2 1 0 0 1 1 1 0 Tropomyosin Mt_ATP-synt_B PF05405.14 KXL46832.1 - 0.017 14.8 0.4 0.028 14.0 0.4 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) HR1 PF02185.16 KXL46832.1 - 0.019 15.1 4.1 0.043 13.9 4.1 1.6 1 0 0 1 1 1 0 Hr1 repeat V_ATPase_I PF01496.19 KXL46832.1 - 0.041 11.8 0.1 0.051 11.5 0.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TSC22 PF01166.18 KXL46832.1 - 0.089 13.1 0.5 0.19 12.0 0.5 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF2383 PF09537.10 KXL46832.1 - 0.14 12.5 0.7 0.25 11.7 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) TMPIT PF07851.13 KXL46832.1 - 0.4 9.9 1.4 0.55 9.4 1.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF3328 PF11807.8 KXL46833.1 - 3.6e-15 56.4 2.1 4.1e-15 56.2 2.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Phosphoesterase PF04185.14 KXL46834.1 - 5.9e-21 75.0 10.2 2e-20 73.3 7.9 2.4 1 1 1 2 2 2 1 Phosphoesterase family p450 PF00067.22 KXL46836.1 - 1.9e-38 132.4 0.0 2e-38 132.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MgtC PF02308.16 KXL46837.1 - 5.8e-34 117.1 9.6 7.3e-34 116.7 9.6 1.1 1 0 0 1 1 1 1 MgtC family Glyco_hydro_15 PF00723.21 KXL46838.1 - 1.3e-56 192.3 0.0 1.7e-56 191.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 SMP PF04927.12 KXL46839.1 - 0.0023 18.4 2.1 0.0038 17.7 2.1 1.4 1 0 0 1 1 1 1 Seed maturation protein ECH_1 PF00378.20 KXL46840.1 - 1.5e-54 185.0 0.1 2.2e-54 184.4 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXL46840.1 - 3.2e-23 82.8 0.5 5.1e-23 82.1 0.5 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DoxD PF04173.13 KXL46840.1 - 0.011 15.6 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 TQO small subunit DoxD Peptidase_S49 PF01343.18 KXL46840.1 - 0.016 15.2 0.2 0.21 11.5 0.2 2.0 1 1 0 1 1 1 0 Peptidase family S49 Sgf11 PF08209.11 KXL46841.1 - 2.9e-11 42.7 0.2 2.9e-11 42.7 0.2 1.9 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-ACC PF17848.1 KXL46841.1 - 6.7 6.9 5.6 0.52 10.4 0.3 1.8 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zf-C2HC_2 PF13913.6 KXL46841.1 - 9.8 6.2 8.9 0.12 12.3 1.6 1.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Glyco_hydro_39 PF01229.17 KXL46842.1 - 2.8e-47 161.5 0.0 4.2e-47 160.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Serine_rich PF08824.10 KXL46842.1 - 0.21 11.6 0.0 4.7 7.2 0.0 2.1 2 0 0 2 2 2 0 Serine rich protein interaction domain DUF4140 PF13600.6 KXL46843.1 - 5.1e-05 23.6 3.5 0.082 13.3 0.0 2.7 3 0 0 3 3 2 2 N-terminal domain of unknown function (DUF4140) CC2-LZ PF16516.5 KXL46843.1 - 9.7e-05 22.7 0.2 0.044 14.2 0.5 3.0 3 0 0 3 3 3 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator CP12 PF02672.15 KXL46843.1 - 0.0023 18.7 2.0 0.048 14.4 1.3 2.4 2 0 0 2 2 2 1 CP12 domain SOGA PF11365.8 KXL46843.1 - 0.0031 18.6 0.5 0.016 16.3 0.4 2.1 1 1 1 2 2 2 1 Protein SOGA KASH_CCD PF14662.6 KXL46843.1 - 0.0042 16.9 1.5 0.18 11.6 0.4 2.3 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 KXL46843.1 - 0.0048 15.8 0.9 0.12 11.2 0.6 2.1 2 0 0 2 2 2 1 Spc7 kinetochore protein Filament PF00038.21 KXL46843.1 - 0.0054 16.4 0.2 0.2 11.2 0.1 2.1 2 0 0 2 2 2 1 Intermediate filament protein Tropomyosin PF00261.20 KXL46843.1 - 0.0074 15.7 2.4 0.0074 15.7 2.4 1.9 2 0 0 2 2 2 1 Tropomyosin TMF_TATA_bd PF12325.8 KXL46843.1 - 0.013 15.7 1.2 1.9 8.7 0.5 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Prefoldin PF02996.17 KXL46843.1 - 0.02 14.8 1.7 2 8.4 3.1 2.8 3 0 0 3 3 3 0 Prefoldin subunit ZapB PF06005.12 KXL46843.1 - 0.04 14.3 5.3 5.1 7.6 0.0 2.8 2 1 0 2 2 2 0 Cell division protein ZapB APG6_N PF17675.1 KXL46843.1 - 0.051 14.1 3.0 1.3 9.6 2.1 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region Fez1 PF06818.15 KXL46843.1 - 0.064 13.7 0.3 0.11 13.0 0.3 1.3 1 0 0 1 1 1 0 Fez1 TolA_bind_tri PF16331.5 KXL46843.1 - 0.067 13.3 0.7 2.4 8.3 0.0 2.6 2 1 0 2 2 2 0 TolA binding protein trimerisation DUF2408 PF10303.9 KXL46843.1 - 0.068 13.7 1.4 1.6 9.3 1.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) DUF2913 PF11140.8 KXL46843.1 - 0.068 12.9 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2913) MctB PF11382.8 KXL46843.1 - 0.086 12.5 1.7 5.5 6.6 0.0 2.1 2 0 0 2 2 2 0 Copper transport outer membrane protein, MctB Csm1_N PF18504.1 KXL46843.1 - 0.12 12.8 2.5 9.2 6.7 0.7 2.6 2 1 0 2 2 2 0 Csm1 N-terminal domain DivIC PF04977.15 KXL46843.1 - 0.13 12.1 4.3 7.4 6.4 1.5 2.5 2 0 0 2 2 2 0 Septum formation initiator Troponin PF00992.20 KXL46843.1 - 0.17 12.2 1.5 0.35 11.2 0.5 1.9 2 0 0 2 2 2 0 Troponin MAD PF05557.13 KXL46843.1 - 0.18 10.1 0.8 5.1 5.3 0.3 2.0 2 0 0 2 2 2 0 Mitotic checkpoint protein HR1 PF02185.16 KXL46843.1 - 0.2 11.8 2.3 3.4 7.8 0.3 2.4 2 0 0 2 2 2 0 Hr1 repeat MPS2 PF17060.5 KXL46843.1 - 0.24 10.6 1.2 7.6 5.7 0.0 2.1 1 1 0 2 2 2 0 Monopolar spindle protein 2 SlyX PF04102.12 KXL46843.1 - 0.25 12.0 2.5 26 5.5 0.3 2.9 2 1 1 3 3 3 0 SlyX CENP-F_leu_zip PF10473.9 KXL46843.1 - 0.25 11.3 4.0 6.7 6.7 0.7 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lebercilin PF15619.6 KXL46843.1 - 0.38 10.4 5.4 4.9 6.8 0.8 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF1515 PF07439.11 KXL46843.1 - 0.5 10.4 2.3 6.9 6.7 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Takusan PF04822.13 KXL46843.1 - 0.99 9.3 3.0 16 5.4 0.0 2.5 2 1 0 2 2 2 0 Takusan TRAF_BIRC3_bd PF16673.5 KXL46843.1 - 1.1 9.0 7.1 0.5 10.2 3.0 2.2 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain Cep57_CLD_2 PF14197.6 KXL46843.1 - 2.3 8.4 8.2 16 5.6 0.4 2.9 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 TSC22 PF01166.18 KXL46843.1 - 2.9 8.3 4.2 13 6.2 0.0 3.2 3 1 1 4 4 3 0 TSC-22/dip/bun family MCPVI PF02993.14 KXL46843.1 - 3.4 7.4 6.2 2.8 7.7 2.0 2.2 1 1 1 2 2 2 0 Minor capsid protein VI HrpB7 PF09486.10 KXL46843.1 - 4.7 7.6 12.0 0.31 11.4 2.0 2.5 3 0 0 3 3 2 0 Bacterial type III secretion protein (HrpB7) Pox_A_type_inc PF04508.12 KXL46843.1 - 9.5 6.3 9.5 0.27 11.1 2.0 2.4 3 0 0 3 3 1 0 Viral A-type inclusion protein repeat Alpha-amylase PF00128.24 KXL46844.1 - 8.9e-105 350.9 0.0 1.3e-104 350.4 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KXL46844.1 - 2.1e-07 30.9 0.0 4.9e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KXL46844.1 - 0.0036 16.4 0.0 0.0053 15.9 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain p450 PF00067.22 KXL46846.1 - 5.4e-27 94.7 0.0 6.3e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DDE_1 PF03184.19 KXL46847.1 - 0.024 14.3 0.0 0.026 14.2 0.0 1.0 1 0 0 1 1 1 0 DDE superfamily endonuclease Sulfotransfer_4 PF17784.1 KXL46848.1 - 8.4e-55 185.9 0.0 9.8e-55 185.7 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXL46848.1 - 9.5e-05 22.9 0.1 0.011 16.2 0.0 2.3 1 1 0 2 2 2 2 Sulfotransferase family Caps_synth PF05704.12 KXL46849.1 - 1.2e-11 44.5 0.1 2.3e-11 43.6 0.1 1.4 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 KXL46849.1 - 2.5e-05 24.8 0.0 4.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif p450 PF00067.22 KXL46850.1 - 1.2e-30 106.7 0.8 1.5e-30 106.4 0.8 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KXL46851.1 - 2.4e-23 82.6 0.3 4e-18 65.4 0.0 2.7 2 1 0 2 2 2 2 Cytochrome P450 ketoacyl-synt PF00109.26 KXL46852.1 - 4.7e-68 229.5 0.1 7.5e-68 228.8 0.1 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXL46852.1 - 2.6e-60 203.4 0.3 1.3e-59 201.1 0.0 2.4 3 0 0 3 3 2 1 KR domain PS-DH PF14765.6 KXL46852.1 - 2.6e-55 187.8 0.0 4.4e-55 187.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KXL46852.1 - 1.2e-47 162.9 0.0 1.2e-46 159.7 0.0 2.4 2 1 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXL46852.1 - 1.5e-36 125.0 0.1 3.3e-36 123.9 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KXL46852.1 - 9.4e-19 68.0 0.0 2.4e-18 66.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 KXL46852.1 - 5.4e-17 62.0 0.0 2.5e-15 56.6 0.0 3.3 3 0 0 3 3 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 KXL46852.1 - 3.1e-14 52.9 0.0 1.5e-13 50.6 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 KXL46852.1 - 4.1e-13 50.5 0.0 2.8e-12 47.9 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 KXL46852.1 - 5.7e-12 46.1 0.0 3e-10 40.5 0.0 2.8 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Methyltransf_31 PF13847.6 KXL46852.1 - 3.4e-09 36.7 0.0 1.2e-08 34.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KXL46852.1 - 6.1e-09 35.8 0.0 2.6e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_25 PF13649.6 KXL46852.1 - 7.3e-08 33.0 0.0 2.7e-07 31.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXL46852.1 - 1.1e-07 31.8 0.0 7.8e-07 29.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL46852.1 - 2e-07 31.5 0.0 5e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.12 KXL46852.1 - 2.3e-07 30.7 0.1 7.8e-07 29.0 0.1 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 KXL46852.1 - 1.8e-06 28.2 0.2 4.1e-06 27.0 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KXL46852.1 - 0.00039 19.9 0.1 0.0011 18.4 0.1 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 KXL46852.1 - 0.0053 16.1 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 KXL46852.1 - 0.013 15.2 0.0 0.035 13.7 0.0 1.7 1 0 0 1 1 1 0 Nodulation protein S (NodS) RE_Bsp6I PF09504.10 KXL46852.1 - 0.045 13.3 0.0 0.5 9.9 0.0 2.2 2 0 0 2 2 2 0 Bsp6I restriction endonuclease FSH1 PF03959.13 KXL46853.1 - 7.6e-24 84.6 0.0 4.7e-23 82.0 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) GTP_cyclohydro2 PF00925.20 KXL46854.1 - 9.8e-56 187.8 0.0 1.9e-55 186.9 0.0 1.4 1 1 0 1 1 1 1 GTP cyclohydrolase II Aldedh PF00171.22 KXL46855.1 - 7.9e-158 525.8 0.3 8.8e-158 525.6 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KXL46855.1 - 3.1e-06 26.8 0.0 8.8e-06 25.3 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) HOOK PF05622.12 KXL46857.1 - 2.2e-21 75.8 64.4 1.1e-14 53.6 0.0 4.0 1 1 2 3 3 3 3 HOOK protein TPR_MLP1_2 PF07926.12 KXL46857.1 - 0.0083 16.2 24.9 0.0083 16.2 24.9 4.4 2 2 2 4 4 4 2 TPR/MLP1/MLP2-like protein Phage_int_SAM_1 PF02899.17 KXL46857.1 - 0.072 13.4 2.8 0.25 11.6 0.7 3.1 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Speriolin_N PF15058.6 KXL46857.1 - 0.8 9.8 3.9 2.3 8.3 3.9 1.8 1 0 0 1 1 1 0 Speriolin N terminus FlaC_arch PF05377.11 KXL46857.1 - 1.2 9.5 19.1 9.8 6.7 0.1 5.7 3 1 2 5 5 5 0 Flagella accessory protein C (FlaC) Tyrosinase PF00264.20 KXL46857.1 - 5.4 7.2 8.2 0.55 10.5 0.4 2.8 1 1 2 3 3 3 0 Common central domain of tyrosinase NCE101 PF11654.8 KXL46858.1 - 5.8e-11 41.9 0.0 7.5e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Non-classical export protein 1 DUF465 PF04325.13 KXL46858.1 - 0.073 13.1 0.7 0.1 12.7 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF465) Phage_holin_3_6 PF07332.11 KXL46858.1 - 0.13 12.3 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Atg8 PF02991.16 KXL46859.1 - 6e-51 171.0 0.2 8.7e-51 170.4 0.2 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KXL46859.1 - 5.4e-06 26.7 0.0 9.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 PMT_4TMC PF16192.5 KXL46860.1 - 4.1e-66 222.4 18.9 4.1e-66 222.4 18.9 2.7 2 1 1 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase PMT PF02366.18 KXL46860.1 - 2.7e-64 217.1 14.2 2.7e-64 217.1 14.2 2.3 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.19 KXL46860.1 - 1.4e-34 119.6 2.0 2.1e-34 119.0 2.0 1.2 1 0 0 1 1 1 1 MIR domain WW PF00397.26 KXL46862.1 - 0.0012 18.8 0.6 0.0012 18.8 0.6 2.1 3 0 0 3 3 3 1 WW domain Hva1_TUDOR PF11160.8 KXL46862.1 - 0.38 11.0 1.9 4.5 7.5 0.1 2.3 1 1 1 2 2 2 0 Hypervirulence associated proteins TUDOR domain Thymidylate_kin PF02223.17 KXL46862.1 - 0.45 10.2 2.0 0.74 9.5 2.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase DUF2235 PF09994.9 KXL46863.1 - 5.8e-75 252.3 0.0 7.3e-75 252.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) zf-RING_2 PF13639.6 KXL46864.1 - 1.6e-08 34.7 6.8 1.6e-08 34.7 6.8 2.0 2 0 0 2 2 2 1 Ring finger domain FANCL_C PF11793.8 KXL46864.1 - 0.0051 17.0 7.0 0.0051 17.0 7.0 2.1 2 1 0 2 2 2 1 FANCL C-terminal domain PHD PF00628.29 KXL46864.1 - 0.0053 16.6 6.8 0.011 15.6 6.8 1.5 1 0 0 1 1 1 1 PHD-finger RINGv PF12906.7 KXL46864.1 - 0.011 15.8 4.7 0.019 15.1 3.9 1.9 1 1 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.6 KXL46864.1 - 0.019 15.0 3.6 0.048 13.7 3.6 1.7 1 0 0 1 1 1 0 RING-type zinc-finger DTHCT PF08070.11 KXL46864.1 - 0.021 15.6 2.3 0.036 14.8 2.3 1.4 1 0 0 1 1 1 0 DTHCT (NUC029) region zf-RING_5 PF14634.6 KXL46864.1 - 0.26 11.3 11.3 0.044 13.7 7.6 1.7 2 0 0 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KXL46864.1 - 0.54 10.2 6.3 0.35 10.8 0.2 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KXL46864.1 - 1.2 9.3 9.1 0.05 13.7 2.5 2.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.6 KXL46864.1 - 5.5 7.0 17.6 0.07 13.1 5.9 2.7 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 zf-rbx1 PF12678.7 KXL46864.1 - 7.3 7.0 12.6 0.24 11.7 5.9 2.0 2 1 0 2 2 2 0 RING-H2 zinc finger domain Nop PF01798.18 KXL46865.1 - 3.5e-85 285.1 0.0 3.5e-85 285.1 0.0 1.7 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KXL46865.1 - 1.5e-19 70.1 0.1 1.5e-19 70.1 0.1 2.5 3 0 0 3 3 3 1 NOP5NT (NUC127) domain Cpn60_TCP1 PF00118.24 KXL46866.1 - 1.6e-165 551.5 0.0 1.8e-165 551.3 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Herpes_UL6 PF01763.16 KXL46866.1 - 0.1 11.1 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like MFS_1 PF07690.16 KXL46867.1 - 5.5e-33 114.4 35.9 5.5e-33 114.4 35.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL46867.1 - 1.5e-11 43.9 8.9 1.5e-11 43.9 8.9 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter AcrZ PF10766.9 KXL46867.1 - 2.4 7.8 5.3 3.4 7.3 0.8 2.7 2 0 0 2 2 2 0 Multidrug efflux pump-associated protein AcrZ Zn_clus PF00172.18 KXL46868.1 - 5.2e-09 36.1 11.5 9.2e-09 35.3 11.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PDEase_I PF00233.19 KXL46868.1 - 0.23 11.2 0.2 0.35 10.5 0.2 1.2 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase LETM1 PF07766.13 KXL46869.1 - 3.3e-21 75.8 1.2 2.8e-13 49.8 0.1 2.1 2 0 0 2 2 2 2 LETM1-like protein JAB PF01398.21 KXL46871.1 - 1.7e-12 47.3 0.0 2.8e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 KXL46871.1 - 5.3e-07 29.4 0.0 1.2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain USP8_dimer PF08969.11 KXL46871.1 - 0.00092 19.4 0.0 0.0014 18.8 0.0 1.3 1 0 0 1 1 1 1 USP8 dimerisation domain DUF1744 PF08490.12 KXL46873.1 - 4.5e-148 493.1 0.1 6.2e-148 492.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 KXL46873.1 - 1.6e-82 277.4 0.0 2.8e-82 276.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 KXL46873.1 - 5.6e-15 55.0 2.3 9.8e-13 47.6 0.2 3.4 2 2 0 2 2 2 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 KXL46873.1 - 7.4e-10 38.9 0.0 2e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KXL46873.1 - 0.00011 22.2 0.0 0.00033 20.7 0.0 1.8 1 0 0 1 1 1 1 RNase_H superfamily IFN-gamma PF00714.17 KXL46873.1 - 0.16 11.8 0.1 0.52 10.2 0.1 1.9 1 0 0 1 1 1 0 Interferon gamma DUF3767 PF12597.8 KXL46874.1 - 3.5e-25 87.8 0.1 3.5e-25 87.8 0.1 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF3767) K_channel_TID PF07941.11 KXL46874.1 - 0.28 11.7 6.1 0.62 10.5 6.1 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain iPGM_N PF06415.13 KXL46875.1 - 1.6e-75 253.3 0.0 2.3e-75 252.8 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 KXL46875.1 - 8.4e-70 235.0 0.1 9.8e-70 234.7 0.1 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KXL46875.1 - 3.1e-05 23.5 0.0 0.00017 21.1 0.0 2.2 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 KXL46875.1 - 7.8e-05 22.4 0.0 0.00029 20.5 0.0 1.6 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Alk_phosphatase PF00245.20 KXL46875.1 - 0.032 13.2 0.1 0.33 9.9 0.0 2.2 2 0 0 2 2 2 0 Alkaline phosphatase Med9 PF07544.13 KXL46876.1 - 1.2e-13 50.9 0.0 1.5e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.8 KXL46876.1 - 0.056 13.7 3.2 0.086 13.1 3.2 1.6 1 1 0 1 1 1 0 Subunit 21 of Mediator complex DUF2183 PF09949.9 KXL46877.1 - 9.6e-34 115.7 0.0 1.7e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Pkinase PF00069.25 KXL46878.1 - 8.6e-72 241.7 0.0 1e-71 241.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL46878.1 - 8e-30 104.0 0.0 1e-29 103.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXL46878.1 - 1.4e-07 31.1 0.0 2.1e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXL46878.1 - 2.9e-05 23.0 0.1 0.00015 20.7 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KXL46878.1 - 0.00014 21.3 0.1 0.00024 20.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXL46878.1 - 0.00031 20.7 0.0 0.00059 19.8 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fis1_TPR_C PF14853.6 KXL46878.1 - 0.043 13.9 0.1 19 5.4 0.0 2.7 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Glyco_hydro_32C PF08244.12 KXL46879.1 - 7.4e-15 55.3 0.0 1e-14 54.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal MAPEG PF01124.18 KXL46880.1 - 8.4e-12 45.1 0.4 1.4e-11 44.5 0.4 1.3 1 0 0 1 1 1 1 MAPEG family Hexapep PF00132.24 KXL46882.1 - 6.6e-15 54.2 11.5 7.8e-11 41.3 4.2 3.3 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KXL46882.1 - 2.8e-14 52.6 10.6 5.7e-12 45.2 5.2 2.3 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Alanine_zipper PF11839.8 KXL46883.1 - 5.2 7.5 9.6 2.2 8.7 1.1 2.5 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein EMG1 PF03587.14 KXL46884.1 - 6.9e-79 264.0 0.0 8.2e-79 263.8 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase ADH_N PF08240.12 KXL46885.1 - 6.8e-34 116.0 0.9 1.2e-33 115.2 0.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXL46885.1 - 1.2e-15 57.6 0.0 2.1e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXL46885.1 - 1.6e-08 34.3 0.0 2.6e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KXL46885.1 - 2.9e-05 25.1 0.0 5e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 KXL46885.1 - 0.028 13.7 0.1 0.039 13.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_3 PF03447.16 KXL46885.1 - 0.045 14.4 0.0 0.12 13.1 0.0 1.7 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain ThiF PF00899.21 KXL46885.1 - 0.17 11.2 0.2 0.39 10.0 0.2 1.5 1 0 0 1 1 1 0 ThiF family Peptidase_M3 PF01432.20 KXL46886.1 - 5.1e-101 339.2 0.0 8.2e-101 338.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M3 Pkr1 PF08636.10 KXL46887.1 - 3.2e-30 104.1 3.8 4.3e-30 103.7 3.8 1.2 1 0 0 1 1 1 1 ER protein Pkr1 SAP30_Sin3_bdg PF13867.6 KXL46888.1 - 0.044 14.1 0.1 0.27 11.6 0.1 1.9 2 0 0 2 2 2 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Xpo1 PF08389.12 KXL46889.1 - 3.3e-23 82.4 0.0 2.3e-22 79.7 0.0 2.6 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 KXL46889.1 - 1.3e-08 34.6 0.1 3.3e-08 33.3 0.1 1.8 1 0 0 1 1 1 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 KXL46889.1 - 6.1e-06 26.5 0.4 0.0021 18.4 0.0 4.4 4 0 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 KXL46889.1 - 0.00082 19.8 1.2 0.039 14.5 0.0 4.1 3 0 0 3 3 3 1 HEAT-like repeat HEAT PF02985.22 KXL46889.1 - 0.0044 17.1 0.0 5.8 7.5 0.0 4.4 3 0 0 3 3 3 1 HEAT repeat LSM PF01423.22 KXL46890.1 - 3.2e-16 58.8 0.0 3.8e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KXL46890.1 - 0.00012 21.7 0.0 0.00017 21.2 0.0 1.2 1 0 0 1 1 1 1 Hfq protein PhnA PF03831.14 KXL46890.1 - 0.05 13.5 0.0 3.1 7.7 0.0 2.1 2 0 0 2 2 2 0 PhnA domain Mob1_phocein PF03637.17 KXL46891.1 - 7.1e-22 78.2 0.0 1e-21 77.7 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family cobW PF02492.19 KXL46892.1 - 5.9e-44 149.7 0.1 8.9e-44 149.2 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 KXL46892.1 - 9.7e-06 25.6 0.6 0.039 13.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase CobW_C PF07683.14 KXL46892.1 - 0.00024 20.9 0.0 0.00047 20.0 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_23 PF13476.6 KXL46892.1 - 0.0004 20.9 0.0 0.00098 19.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXL46892.1 - 0.00082 19.1 1.0 0.042 13.6 0.2 2.3 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 KXL46892.1 - 0.00088 18.3 2.0 0.81 8.6 0.1 2.9 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KXL46892.1 - 0.0025 18.2 0.0 0.0063 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KXL46892.1 - 0.004 17.7 0.1 0.11 13.0 0.1 2.6 2 0 0 2 2 2 1 ABC transporter GTP_EFTU PF00009.27 KXL46892.1 - 0.0045 16.6 3.6 1 8.9 0.1 2.7 3 1 0 3 3 3 2 Elongation factor Tu GTP binding domain TsaE PF02367.17 KXL46892.1 - 0.022 14.7 0.2 0.062 13.3 0.1 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 KXL46892.1 - 0.027 14.7 0.1 0.24 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 KXL46892.1 - 0.058 12.7 0.3 2.8 7.1 0.1 2.2 2 0 0 2 2 2 0 Septin ATPase_2 PF01637.18 KXL46892.1 - 0.062 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 KXL46892.1 - 0.064 13.0 0.1 0.064 13.0 0.1 2.6 3 0 0 3 3 3 0 P-loop containing region of AAA domain T2SSE PF00437.20 KXL46892.1 - 0.085 11.9 0.1 0.18 10.8 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 KXL46892.1 - 0.098 12.7 0.6 0.38 10.9 0.3 2.4 2 1 0 2 2 1 0 50S ribosome-binding GTPase Arf PF00025.21 KXL46892.1 - 0.12 11.9 1.8 4.6 6.7 0.1 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_18 PF13238.6 KXL46892.1 - 0.16 12.5 0.1 0.77 10.3 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KXL46892.1 - 0.17 11.9 0.2 0.49 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Fungal_trans PF04082.18 KXL46895.1 - 8.7e-62 208.6 0.2 1.5e-61 207.8 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KXL46895.1 - 6.1e-06 26.4 9.8 0.0001 22.5 0.6 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXL46895.1 - 0.0013 19.0 7.9 0.063 13.7 2.7 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXL46895.1 - 0.076 13.9 0.5 0.076 13.9 0.5 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger SOG2 PF10428.9 KXL46895.1 - 0.78 8.9 15.5 1.3 8.1 15.5 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein DHHC PF01529.20 KXL46897.1 - 1.1e-35 122.6 4.6 1.1e-35 122.6 4.6 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 KXL46897.1 - 3.3e-27 94.9 0.1 1.4e-10 41.6 0.0 3.7 1 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXL46897.1 - 1.8e-20 73.0 5.4 5.6e-06 26.8 0.4 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXL46897.1 - 7.1e-20 69.0 3.6 6.2e-06 26.2 0.1 6.0 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 KXL46897.1 - 9.1e-19 67.0 3.9 1.5e-05 25.2 0.2 5.7 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KXL46897.1 - 6.8e-16 58.1 1.1 0.00048 20.4 0.1 5.1 2 1 4 6 6 6 5 Ankyrin repeats (many copies) DZR PF12773.7 KXL46897.1 - 1.6 8.8 7.8 3.3 7.8 7.8 1.4 1 0 0 1 1 1 0 Double zinc ribbon adh_short PF00106.25 KXL46898.1 - 8.5e-05 22.1 0.0 0.00033 20.2 0.0 1.9 2 1 0 2 2 2 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 KXL46898.1 - 0.045 14.0 0.0 0.077 13.3 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain LacAB_rpiB PF02502.18 KXL46899.1 - 2.1e-44 150.9 0.3 2.4e-44 150.7 0.3 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.6 KXL46899.1 - 0.016 15.2 0.3 0.17 11.9 0.0 2.1 1 1 1 2 2 2 0 Glycine-rich SFCGS DUF2620 PF10941.8 KXL46899.1 - 0.016 15.3 0.5 0.032 14.4 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF2620 Cyclin PF08613.11 KXL46900.1 - 1.5e-26 93.7 0.0 2.5e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KXL46900.1 - 0.0018 18.0 0.0 0.0027 17.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain HTH_19 PF12844.7 KXL46900.1 - 0.048 13.7 0.0 0.099 12.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Ribosomal_S21 PF01165.20 KXL46901.1 - 1.2e-13 50.5 8.8 2.8e-13 49.4 8.8 1.6 1 0 0 1 1 1 1 Ribosomal protein S21 PWI PF01480.17 KXL46902.1 - 1.2e-11 44.8 0.6 3.8e-11 43.1 0.6 1.9 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 KXL46902.1 - 0.01 15.6 0.0 0.066 13.0 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Borrelia_P83 PF05262.11 KXL46903.1 - 5.7 5.3 20.7 7.8 4.9 20.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein TFIIA PF03153.13 KXL46903.1 - 6.8 6.6 15.0 8.9 6.2 15.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PGI PF00342.19 KXL46904.1 - 7.9e-241 799.8 0.7 9e-241 799.6 0.7 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase ZZ PF00569.17 KXL46905.1 - 1.4e-10 40.8 5.6 1.4e-10 40.8 5.6 1.9 3 0 0 3 3 3 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 KXL46905.1 - 1.1e-09 38.4 0.0 3.3e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 KXL46905.1 - 2.7e-08 34.1 0.0 8.9e-08 32.4 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 KXL46905.1 - 4.5e-06 26.8 0.0 1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF4239 PF14023.6 KXL46905.1 - 0.22 11.2 1.7 0.34 10.6 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Phosducin PF02114.16 KXL46905.1 - 0.59 9.0 3.1 0.95 8.3 3.1 1.3 1 0 0 1 1 1 0 Phosducin Pkinase PF00069.25 KXL46906.1 - 1.6e-70 237.5 0.0 2.2e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL46906.1 - 4.4e-34 117.9 0.0 6.4e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KXL46906.1 - 1.2e-11 45.2 0.2 3.6e-11 43.6 0.2 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KXL46906.1 - 7.4e-06 25.2 0.0 1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain C2 PF00168.30 KXL46906.1 - 0.0052 17.1 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 KXL46906.1 - 0.0053 16.1 0.0 0.0084 15.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 KXL46906.1 - 0.087 12.4 0.1 3.2 7.3 0.1 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 eIF3g PF12353.8 KXL46908.1 - 3e-41 140.7 1.7 4.5e-41 140.2 1.7 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 KXL46908.1 - 4.2e-17 61.7 0.1 7e-17 61.0 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXL46908.1 - 0.046 13.6 0.0 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KXL46908.1 - 0.19 11.7 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif CBS PF00571.28 KXL46910.1 - 1.3e-08 35.2 4.3 0.00018 21.9 0.1 3.4 4 0 0 4 4 4 2 CBS domain COMPASS-Shg1 PF05205.12 KXL46911.1 - 2.3e-19 70.0 0.0 2.3e-19 70.0 0.0 2.3 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 UPF0052 PF01933.18 KXL46913.1 - 1.1e-64 218.6 0.0 1.3e-64 218.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 GFO_IDH_MocA PF01408.22 KXL46914.1 - 2.4e-23 83.2 0.0 3.7e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXL46914.1 - 5.3e-09 36.1 0.0 9.6e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KXL46914.1 - 0.00019 22.1 0.0 0.00033 21.3 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 KXL46914.1 - 0.022 14.9 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Rhomboid PF01694.22 KXL46916.1 - 8.1e-35 120.0 8.1 1.9e-34 118.8 8.1 1.6 1 0 0 1 1 1 1 Rhomboid family CitMHS PF03600.16 KXL46916.1 - 0.036 13.3 0.0 7.7 5.6 0.0 2.2 1 1 1 2 2 2 0 Citrate transporter TssN PF17555.2 KXL46916.1 - 2.9 7.2 5.2 5.6 6.3 5.2 1.4 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF1275 PF06912.11 KXL46917.1 - 1.4e-39 136.0 10.2 1.9e-39 135.6 10.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF1129 PF06570.11 KXL46917.1 - 0.072 12.6 1.4 0.86 9.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) NADH5_C PF06455.11 KXL46917.1 - 0.098 12.2 3.2 0.15 11.7 0.2 2.2 2 0 0 2 2 2 0 NADH dehydrogenase subunit 5 C-terminus Ribosomal_L27A PF00828.19 KXL46918.1 - 3e-32 112.0 0.1 5.1e-32 111.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DnaB_2 PF07261.11 KXL46918.1 - 0.19 11.5 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 Replication initiation and membrane attachment Cyclin PF08613.11 KXL46921.1 - 1.4e-11 45.1 0.0 2.8e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KXL46921.1 - 0.027 14.2 0.1 0.047 13.4 0.1 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain Pyr_redox_2 PF07992.14 KXL46922.1 - 7.7e-53 179.6 0.0 9.6e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXL46922.1 - 8.7e-11 42.2 0.0 2.8e-09 37.4 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXL46922.1 - 0.002 17.4 1.2 0.82 8.9 0.2 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FlxA PF14282.6 KXL46922.1 - 0.067 13.2 1.1 0.14 12.1 1.1 1.5 1 0 0 1 1 1 0 FlxA-like protein DUF4604 PF15377.6 KXL46925.1 - 2.2e-20 73.8 12.3 2.5e-20 73.6 12.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) CAF20 PF17052.5 KXL46925.1 - 1.2 9.3 9.9 0.3 11.2 1.9 2.0 1 1 1 2 2 2 0 Cap associated factor SQS_PSY PF00494.19 KXL46926.1 - 8.7e-50 169.7 0.0 1.2e-49 169.2 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase EzrA PF06160.12 KXL46927.1 - 0.054 11.7 3.1 0.076 11.2 3.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA RNA_pol_Rpc82 PF05645.13 KXL46927.1 - 0.056 13.2 0.5 0.086 12.6 0.5 1.2 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 CENP-F_leu_zip PF10473.9 KXL46927.1 - 0.079 13.0 8.6 0.19 11.7 8.6 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KXL46927.1 - 0.19 10.6 7.5 0.14 11.0 5.9 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein SCAMP PF04144.13 KXL46927.1 - 0.28 11.5 3.2 0.45 10.8 3.2 1.4 1 1 0 1 1 1 0 SCAMP family Prefoldin_2 PF01920.20 KXL46927.1 - 0.89 9.5 7.2 1.8 8.6 6.9 1.6 1 1 0 1 1 1 0 Prefoldin subunit UPF0242 PF06785.11 KXL46927.1 - 2.1 8.4 8.7 87 3.1 8.7 2.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4746 PF15928.5 KXL46928.1 - 0.018 14.5 5.7 0.022 14.2 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CDC45 PF02724.14 KXL46928.1 - 0.86 7.8 3.2 0.86 7.8 3.2 1.0 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 KXL46928.1 - 4 6.7 9.1 5.3 6.3 9.1 1.1 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 KXL46928.1 - 4.5 5.3 7.9 5.1 5.2 7.9 1.0 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 KXL46928.1 - 9.6 5.9 8.6 21 4.7 8.5 1.6 1 1 0 1 1 1 0 FAM176 family SprT-like PF10263.9 KXL46929.1 - 0.00075 19.3 0.0 0.002 17.9 0.0 1.7 1 1 0 1 1 1 1 SprT-like family Pox_A30L_A26L PF06086.12 KXL46930.1 - 0.057 13.1 0.0 0.08 12.6 0.0 1.2 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein Mpv17_PMP22 PF04117.12 KXL46931.1 - 4.1e-12 46.2 1.8 5.4e-11 42.5 1.1 2.2 1 1 1 2 2 2 1 Mpv17 / PMP22 family SelK_SelG PF10961.8 KXL46931.1 - 1.2 9.8 4.4 1.6 9.4 0.1 2.6 3 0 0 3 3 3 0 Selenoprotein SelK_SelG DUF3439 PF11921.8 KXL46933.1 - 0.12 12.4 6.1 4.2 7.4 3.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) ECH_2 PF16113.5 KXL46934.1 - 2e-120 402.3 0.0 2.7e-120 401.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KXL46934.1 - 1.1e-26 93.7 0.0 2.6e-26 92.4 0.0 1.5 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase GTP_EFTU PF00009.27 KXL46935.1 - 1e-57 194.8 0.1 1.4e-57 194.4 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KXL46935.1 - 2.9e-26 91.9 0.0 6.3e-26 90.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KXL46935.1 - 1e-16 61.1 1.2 2.5e-16 59.8 1.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXL46935.1 - 3.6e-05 23.8 0.0 6.7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KXL46935.1 - 0.0083 15.9 0.4 3.5 7.3 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KXL46935.1 - 0.0087 15.7 0.3 0.054 13.1 0.0 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 KXL46935.1 - 0.018 14.9 0.1 0.062 13.2 0.0 1.8 1 1 1 2 2 2 0 RsgA GTPase Thioredoxin PF00085.20 KXL46936.1 - 3.5e-57 190.8 0.0 4.6e-29 100.4 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 KXL46936.1 - 4.6e-20 72.3 0.9 9e-20 71.4 0.0 1.9 3 0 0 3 3 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 KXL46936.1 - 9.7e-17 61.2 0.0 9.2e-08 31.8 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KXL46936.1 - 3.2e-15 56.5 0.0 3.6e-07 30.6 0.0 2.8 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KXL46936.1 - 4.8e-08 33.2 0.0 0.0088 16.4 0.0 3.4 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.6 KXL46936.1 - 7.6e-08 32.4 0.0 0.013 15.7 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 KXL46936.1 - 3.3e-07 30.2 0.0 0.0095 15.8 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 KXL46936.1 - 3.7e-05 23.5 0.1 0.03 14.1 0.0 2.3 2 0 0 2 2 2 2 Redoxin TraF PF13728.6 KXL46936.1 - 0.00016 21.6 0.0 0.33 10.7 0.0 2.2 2 0 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 KXL46936.1 - 0.00078 19.2 0.0 0.54 10.0 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin HyaE PF07449.11 KXL46936.1 - 0.0012 18.8 0.0 0.045 13.7 0.0 2.5 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_6 PF13848.6 KXL46936.1 - 0.0028 17.6 0.0 1.5 8.7 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_3 PF13192.6 KXL46936.1 - 0.0052 16.8 0.0 6.6 6.9 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin domain ERp29_N PF07912.13 KXL46936.1 - 0.014 15.6 0.0 0.34 11.0 0.0 2.3 2 0 0 2 2 2 0 ERp29, N-terminal domain Glutaredoxin PF00462.24 KXL46936.1 - 0.045 14.0 1.6 7.3 6.9 0.2 3.1 2 2 0 2 2 2 0 Glutaredoxin Thioredoxin_4 PF13462.6 KXL46936.1 - 0.057 13.6 0.7 37 4.4 0.0 3.4 3 1 1 4 4 4 0 Thioredoxin PMP1_2 PF08114.11 KXL46939.1 - 0.048 13.4 0.1 0.065 13.0 0.1 1.2 1 0 0 1 1 1 0 ATPase proteolipid family DUF4381 PF14316.6 KXL46939.1 - 0.071 13.4 0.0 0.074 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Gram_pos_anchor PF00746.21 KXL46939.1 - 0.13 12.2 0.2 0.19 11.7 0.2 1.2 1 0 0 1 1 1 0 LPXTG cell wall anchor motif E1-E2_ATPase PF00122.20 KXL46940.1 - 2.2e-34 118.5 5.9 2e-32 112.2 0.1 4.1 4 1 0 4 4 4 2 E1-E2 ATPase Hydrolase PF00702.26 KXL46940.1 - 3.4e-17 63.4 0.1 7.4e-17 62.3 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXL46940.1 - 3.2e-11 42.7 0.0 1e-10 41.1 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXL46940.1 - 0.0012 18.7 0.2 0.0035 17.1 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXL46940.1 - 0.023 14.8 0.0 0.051 13.7 0.0 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) FAM176 PF14851.6 KXL46940.1 - 1.3 8.6 3.8 10 5.8 0.5 3.1 3 0 0 3 3 3 0 FAM176 family Chs7 PF12271.8 KXL46941.1 - 9e-121 402.6 16.8 1e-120 402.5 16.8 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone PIG-L PF02585.17 KXL46942.1 - 1.9e-23 83.5 0.0 2.9e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase OHCU_decarbox PF09349.10 KXL46943.1 - 1.4e-47 162.1 0.8 1.5e-47 161.9 0.8 1.0 1 0 0 1 1 1 1 OHCU decarboxylase BLOC1_2 PF10046.9 KXL46943.1 - 0.015 15.6 0.2 0.15 12.4 0.2 2.2 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IFT20 PF14931.6 KXL46943.1 - 0.042 14.0 1.6 0.066 13.4 0.4 1.8 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 DUF5327 PF17261.2 KXL46943.1 - 0.1 13.4 2.7 1.3 9.8 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5327) Epimerase PF01370.21 KXL46944.1 - 3.4e-21 75.8 0.0 4.5e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXL46944.1 - 2.6e-12 46.8 0.0 7.9e-12 45.2 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXL46944.1 - 5.8e-11 41.9 0.0 7.3e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KXL46944.1 - 2.7e-06 26.7 0.0 9.2e-06 25.0 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KXL46944.1 - 7.9e-05 21.9 0.1 0.19 10.9 0.0 2.6 2 1 0 2 2 2 2 Male sterility protein adh_short PF00106.25 KXL46944.1 - 0.00085 18.8 0.0 0.0022 17.5 0.0 1.8 2 1 0 2 2 2 1 short chain dehydrogenase Ldh_1_N PF00056.23 KXL46944.1 - 0.014 15.5 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KXL46944.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain adh_short PF00106.25 KXL46945.1 - 8.1e-05 22.2 0.0 0.16 11.4 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXL46945.1 - 0.00094 18.8 0.0 0.33 10.5 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase DUF1752 PF08550.10 KXL46947.1 - 2.6e-13 49.5 1.9 2.6e-13 49.5 1.9 1.6 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) DLH PF01738.18 KXL46950.1 - 3.5e-18 66.0 0.1 4.3e-18 65.7 0.1 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family BTB PF00651.31 KXL46951.1 - 4.6e-21 75.1 0.2 4.5e-11 42.9 0.2 2.9 3 0 0 3 3 3 2 BTB/POZ domain Ank_4 PF13637.6 KXL46951.1 - 6.3e-08 33.0 0.1 3.1e-07 30.8 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXL46951.1 - 1e-06 28.9 0.0 3.1e-06 27.3 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXL46951.1 - 1.9e-06 28.4 0.0 4e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXL46951.1 - 4.7e-06 26.8 0.7 0.013 16.0 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KXL46951.1 - 0.00026 21.2 0.3 0.12 13.0 0.0 3.3 2 0 0 2 2 2 1 Ankyrin repeat Pkinase PF00069.25 KXL46952.1 - 6.9e-55 186.2 0.0 7.8e-55 186.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL46952.1 - 1.1e-37 129.7 0.0 1.5e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXL46952.1 - 9e-06 25.2 0.0 1.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXL46952.1 - 0.0017 18.3 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KXL46952.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Cys_Met_Meta_PP PF01053.20 KXL46953.1 - 1.3e-136 455.1 0.0 1.5e-136 454.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KXL46953.1 - 1.8e-07 30.7 0.0 3.1e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KXL46953.1 - 1.4e-06 27.9 0.6 2.4e-06 27.1 0.6 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KXL46953.1 - 5.7e-05 22.2 0.2 0.00011 21.3 0.2 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KXL46953.1 - 0.0021 17.4 0.1 0.0043 16.4 0.1 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase PRKCSH PF07915.13 KXL46954.1 - 1.3e-17 64.6 0.1 5.1e-17 62.7 0.1 2.1 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 KXL46954.1 - 0.00096 18.9 0.1 0.0044 16.7 0.1 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein DUF295 PF03478.18 KXL46954.1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF295) Sds3 PF08598.11 KXL46955.1 - 1.2e-12 48.3 1.8 1.2e-12 48.3 1.8 1.8 2 0 0 2 2 2 1 Sds3-like DUF4110 PF13422.6 KXL46955.1 - 0.066 13.3 4.8 0.29 11.2 4.8 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) RRM_1 PF00076.22 KXL46956.1 - 8.2e-11 41.6 0.0 3.3e-09 36.5 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PMT PF02366.18 KXL46957.1 - 5.6e-85 284.8 17.9 9e-85 284.2 17.9 1.3 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KXL46957.1 - 3.4e-68 229.2 6.4 3.4e-68 229.2 6.4 3.3 2 1 2 4 4 4 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KXL46957.1 - 2.6e-15 56.8 0.0 4.8e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 KXL46957.1 - 0.0034 17.6 10.1 0.0034 17.6 10.1 2.8 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase UCR_Fe-S_N PF10399.9 KXL46957.1 - 5 6.6 6.7 16 5.0 6.7 1.8 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Amdase PF17645.1 KXL46958.1 - 2.7e-14 53.3 0.1 5.9e-09 35.9 0.0 2.1 1 1 1 2 2 2 2 Arylmalonate decarboxylase Asp_Glu_race PF01177.22 KXL46958.1 - 2.8e-07 30.6 0.8 1.4e-05 25.0 0.8 2.5 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase ATP-synt_ab PF00006.25 KXL46960.1 - 1.3e-72 243.9 0.0 2.1e-72 243.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KXL46960.1 - 2e-48 163.9 0.5 3.4e-48 163.1 0.5 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KXL46960.1 - 5e-16 59.0 2.9 5e-16 59.0 2.9 2.4 3 0 0 3 3 3 1 ATP synthase alpha/beta family, beta-barrel domain Radical_SAM_C PF16199.5 KXL46960.1 - 0.19 11.8 0.0 0.4 10.7 0.0 1.5 1 0 0 1 1 1 0 Radical_SAM C-terminal domain DUF962 PF06127.11 KXL46961.1 - 7.3e-25 86.9 2.1 1e-24 86.4 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF962) SPT2 PF08243.11 KXL46962.1 - 2.5e-08 34.4 15.4 2.5e-08 34.4 15.4 2.7 2 1 1 3 3 3 1 SPT2 chromatin protein Ribosomal_60s PF00428.19 KXL46963.1 - 1.8e-27 95.7 13.1 2.1e-27 95.5 13.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein EF-hand_14 PF17959.1 KXL46963.1 - 0.013 15.8 0.0 0.019 15.3 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain DUF3138 PF11336.8 KXL46963.1 - 0.15 10.7 0.8 0.14 10.7 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Ribosomal_S19 PF00203.21 KXL46964.1 - 3.2e-34 116.7 0.4 4.4e-34 116.2 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 SHS2_Rpb7-N PF03876.17 KXL46965.1 - 4.2e-11 43.0 0.0 7.9e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KXL46965.1 - 2.2e-09 37.5 0.2 3.9e-09 36.7 0.2 1.4 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 KXL46965.1 - 0.0005 20.3 0.0 0.00096 19.4 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 MRP-S35 PF10246.9 KXL46965.1 - 0.24 11.4 0.5 8.2 6.4 0.5 2.2 1 1 0 1 1 1 0 Mitochondrial ribosomal protein MRP-S35 Dynamin_M PF01031.20 KXL46966.1 - 1.2e-108 362.6 0.0 2.6e-108 361.6 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KXL46966.1 - 4e-59 199.4 1.5 7.3e-57 192.1 0.0 2.8 3 0 0 3 3 3 2 Dynamin family GED PF02212.18 KXL46966.1 - 5.7e-33 112.9 2.6 2.9e-32 110.7 3.0 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KXL46966.1 - 0.00011 22.3 2.7 0.0015 18.6 0.4 3.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase WD40 PF00400.32 KXL46968.1 - 3.5e-33 113.1 22.5 6.6e-08 33.1 0.2 8.3 7 1 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.11 KXL46968.1 - 2.8e-12 45.9 6.9 4.9e-12 45.2 6.9 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 KXL46968.1 - 1.5e-10 41.2 0.0 0.22 11.8 0.0 5.2 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Recep_L_domain PF01030.24 KXL46969.1 - 7.8e-07 29.2 5.8 0.026 14.6 0.2 4.5 1 1 3 4 4 4 3 Receptor L domain Helicase_C PF00271.31 KXL46969.1 - 0.055 13.8 0.1 0.16 12.3 0.1 1.8 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Na_Ca_ex PF01699.24 KXL46969.1 - 0.8 9.7 6.8 0.53 10.2 0.1 2.5 2 0 0 2 2 2 0 Sodium/calcium exchanger protein Pirin PF02678.16 KXL46970.1 - 1.1e-30 105.8 0.3 2.3e-30 104.8 0.2 1.6 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 KXL46970.1 - 3.4e-20 72.3 0.0 5.4e-19 68.5 0.0 2.1 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 KXL46970.1 - 4.3e-06 26.3 0.7 8.5e-05 22.2 0.9 2.3 2 0 0 2 2 2 1 Cupin domain Brix PF04427.18 KXL46971.1 - 2.9e-40 138.5 0.5 3.9e-40 138.0 0.5 1.2 1 0 0 1 1 1 1 Brix domain Glutaredoxin PF00462.24 KXL46972.1 - 1.4e-21 76.5 0.0 3.4e-19 68.8 0.0 2.5 2 0 0 2 2 2 2 Glutaredoxin Thioredoxin PF00085.20 KXL46972.1 - 6.1e-14 51.9 0.0 1.3e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KXL46972.1 - 4.5e-05 23.7 0.0 0.013 15.8 0.0 2.5 1 1 1 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 KXL46972.1 - 0.022 14.1 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family HyaE PF07449.11 KXL46972.1 - 0.11 12.5 0.0 0.47 10.4 0.0 2.0 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE Glyco_transf_34 PF05637.12 KXL46973.1 - 2.6e-66 223.7 0.4 9.8e-66 221.9 0.4 1.9 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF5134 PF17197.4 KXL46974.1 - 0.13 12.2 2.7 0.083 12.8 0.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5134) Abhydrolase_1 PF00561.20 KXL46975.1 - 2.3e-19 70.1 0.0 2.3e-16 60.2 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXL46975.1 - 8.3e-19 69.1 7.0 1e-18 68.8 7.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXL46975.1 - 2.1e-05 23.9 0.0 8.7e-05 21.9 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 EHN PF06441.12 KXL46975.1 - 0.19 12.1 0.2 0.42 11.0 0.2 1.5 1 0 0 1 1 1 0 Epoxide hydrolase N terminus COX14 PF14880.6 KXL46976.1 - 5.3e-12 45.4 0.1 5.3e-12 45.4 0.1 1.9 2 0 0 2 2 2 1 Cytochrome oxidase c assembly DUF2458 PF10454.9 KXL46977.1 - 5e-53 179.3 0.0 6.1e-53 179.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) Chitin_bind_1 PF00187.19 KXL46978.1 - 0.03 14.8 15.4 0.048 14.1 15.4 1.3 1 0 0 1 1 1 0 Chitin recognition protein zf_C2HC_14 PF18574.1 KXL46979.1 - 0.037 13.8 1.3 0.037 13.8 1.3 1.8 2 0 0 2 2 2 0 C2HC Zing finger domain DNA_pol_phi PF04931.13 KXL46980.1 - 3.8 5.5 7.4 6.1 4.8 7.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi FmiP_Thoc5 PF09766.9 KXL46981.1 - 0.00096 18.5 1.1 0.00096 18.5 1.1 1.7 2 0 0 2 2 2 1 Fms-interacting protein/Thoc5 Ras PF00071.22 KXL46983.1 - 9.4e-51 171.6 0.0 1.1e-50 171.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXL46983.1 - 4.6e-21 75.3 0.0 6.8e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXL46983.1 - 1.3e-07 31.2 0.0 1.7e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXL46983.1 - 0.00046 19.8 0.0 0.0026 17.3 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KXL46983.1 - 0.016 14.6 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ADH_zinc_N PF00107.26 KXL46983.1 - 0.025 14.6 0.0 1.3 9.0 0.0 2.2 2 0 0 2 2 2 0 Zinc-binding dehydrogenase SRPRB PF09439.10 KXL46983.1 - 0.034 13.6 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_21 PF13304.6 KXL46983.1 - 0.21 11.3 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system NST1 PF13945.6 KXL46984.1 - 3.4e-52 177.4 5.0 3.4e-52 177.4 5.0 5.4 5 2 1 6 6 6 1 Salt tolerance down-regulator Red1 PF07964.11 KXL46984.1 - 6.1 4.9 43.7 14 3.7 43.7 1.7 1 0 0 1 1 1 0 Rec10 / Red1 Kelch_4 PF13418.6 KXL46985.1 - 2e-21 75.7 8.5 4.1e-08 33.1 0.1 5.3 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KXL46985.1 - 5.6e-20 71.1 0.1 5.2e-05 23.4 0.0 5.5 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KXL46985.1 - 1.2e-16 60.3 0.2 9.4e-05 22.6 0.1 5.7 4 1 1 5 5 5 4 Kelch motif Kelch_1 PF01344.25 KXL46985.1 - 1.4e-15 56.6 0.1 4.4e-05 23.0 0.0 4.5 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 KXL46985.1 - 3.7e-15 55.5 1.4 0.0011 18.9 0.0 5.7 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 KXL46985.1 - 4.3e-08 32.8 8.0 0.0071 16.3 0.0 5.5 7 0 0 7 7 7 3 Kelch motif DUF4741 PF15897.5 KXL46985.1 - 0.019 14.8 1.1 2.4 7.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4741) Fungal_trans PF04082.18 KXL46987.1 - 2.2e-09 36.7 0.1 3.1e-09 36.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL46987.1 - 3.8e-07 30.1 8.8 7e-07 29.3 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BPS1 PF05633.11 KXL46987.1 - 0.14 11.1 0.2 0.65 8.9 0.0 1.9 2 0 0 2 2 2 0 Protein BYPASS1-related HEPN_STY4199 PF18729.1 KXL46988.1 - 0.16 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 STY4199-like HEPN Cupin_1 PF00190.22 KXL46990.1 - 2.5e-39 134.3 0.0 3.2e-20 72.3 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KXL46990.1 - 8e-24 83.1 0.8 9.5e-11 41.3 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KXL46990.1 - 1.1e-10 41.0 0.0 0.0005 19.7 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KXL46990.1 - 5.2e-06 26.4 0.1 0.001 19.0 0.1 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain CENP-C_C PF11699.8 KXL46990.1 - 0.0016 18.6 0.0 0.37 11.0 0.0 2.5 2 0 0 2 2 2 1 Mif2/CENP-C like ARD PF03079.14 KXL46990.1 - 0.0095 16.1 0.2 2.9 8.0 0.0 2.3 2 0 0 2 2 2 2 ARD/ARD' family MannoseP_isomer PF01050.18 KXL46990.1 - 0.025 14.4 0.0 2.1 8.2 0.0 2.1 2 0 0 2 2 2 0 Mannose-6-phosphate isomerase BiPBP_C PF06832.12 KXL46990.1 - 0.052 13.6 0.2 5.1 7.2 0.1 2.7 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family Sulfate_transp PF00916.20 KXL46991.1 - 2.7e-80 270.0 14.1 3.6e-80 269.5 14.1 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KXL46991.1 - 2.2e-14 53.1 0.0 4.4e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 STAS domain zf-RING_2 PF13639.6 KXL46992.1 - 7.5e-11 42.2 4.5 1.2e-10 41.6 4.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXL46992.1 - 2.9e-09 36.5 2.0 4.9e-09 35.8 2.0 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KXL46992.1 - 1.5e-07 31.1 2.6 2.4e-07 30.5 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXL46992.1 - 7.3e-07 28.9 3.8 1.2e-06 28.3 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXL46992.1 - 1.6e-05 25.1 6.1 4.9e-05 23.5 6.1 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KXL46992.1 - 4.5e-05 23.2 3.6 8.2e-05 22.4 3.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXL46992.1 - 0.00055 19.8 1.5 0.00087 19.2 1.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXL46992.1 - 0.0028 17.7 3.3 0.0052 16.8 3.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KXL46992.1 - 0.0049 16.9 0.6 0.01 15.9 0.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KXL46992.1 - 0.02 14.7 1.4 0.034 14.0 1.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1180 PF06679.12 KXL46992.1 - 0.045 14.2 1.1 0.14 12.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) zf-RING_4 PF14570.6 KXL46992.1 - 0.094 12.5 3.6 0.16 11.8 3.6 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TMEM154 PF15102.6 KXL46992.1 - 0.12 12.2 0.1 0.25 11.2 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF5305 PF17231.2 KXL46992.1 - 0.19 11.1 0.1 0.51 9.7 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5305) p450 PF00067.22 KXL46993.1 - 3.4e-41 141.5 0.0 4.2e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Y_phosphatase PF00102.27 KXL46994.1 - 1.8e-56 191.3 11.1 1.1e-49 169.1 6.8 3.2 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.20 KXL46994.1 - 1e-12 48.5 0.0 3.9e-12 46.6 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.20 KXL46994.1 - 0.013 15.3 1.6 0.018 14.8 0.1 2.0 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KXL46994.1 - 0.014 15.4 0.9 0.044 13.7 0.9 1.9 1 1 0 1 1 1 0 Tyrosine phosphatase family Abhydrolase_3 PF07859.13 KXL46995.1 - 9.1e-40 136.8 0.1 4.2e-30 105.2 0.1 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXL46995.1 - 2.6e-13 49.6 0.0 4.2e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase adh_short PF00106.25 KXL46996.1 - 1.3e-32 112.9 0.0 2e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL46996.1 - 5.1e-32 111.3 0.0 1.7e-31 109.6 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL46996.1 - 1.2e-07 31.9 0.2 7.6e-07 29.2 0.1 2.0 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 KXL46996.1 - 0.0014 17.8 0.0 0.0022 17.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 KXL46996.1 - 0.03 14.4 0.1 0.11 12.5 0.1 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF1776 PF08643.10 KXL46996.1 - 0.031 13.6 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.26 KXL46996.1 - 0.039 13.9 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Acetyltransf_1 PF00583.25 KXL46997.1 - 6e-08 32.9 0.0 8.7e-08 32.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXL46997.1 - 6.7e-08 32.5 0.0 1.3e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXL46997.1 - 1.8e-07 31.5 0.0 3.7e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXL46997.1 - 0.0026 17.8 0.0 0.016 15.3 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXL46997.1 - 0.022 14.9 0.0 0.039 14.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase bZIP_1 PF00170.21 KXL46998.1 - 0.0094 16.0 9.9 0.023 14.8 9.9 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXL46998.1 - 0.089 12.9 16.0 0.19 11.9 16.0 1.6 1 0 0 1 1 1 0 Basic region leucine zipper Fumble PF03630.14 KXL46999.1 - 6.8e-142 472.5 0.0 8.6e-142 472.2 0.0 1.1 1 0 0 1 1 1 1 Fumble Rtf2 PF04641.12 KXL47000.1 - 3.5e-55 187.2 0.9 4.7e-55 186.8 0.9 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 KXL47000.1 - 5.9e-06 26.0 0.0 8.3e-05 22.3 0.0 2.3 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 KXL47000.1 - 0.025 14.3 0.5 0.72 9.7 0.0 2.3 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_2 PF13639.6 KXL47000.1 - 0.033 14.5 0.0 0.53 10.7 0.1 2.2 1 1 1 2 2 2 0 Ring finger domain zf-RING_5 PF14634.6 KXL47000.1 - 0.037 14.0 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXL47000.1 - 0.085 12.9 0.0 0.33 11.0 0.0 2.0 1 1 1 2 2 2 0 RING-type zinc-finger Ndc1_Nup PF09531.10 KXL47000.1 - 4.5 5.8 6.4 7.2 5.2 6.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GMC_oxred_N PF00732.19 KXL47001.1 - 1.5e-50 172.3 0.0 2.2e-50 171.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXL47001.1 - 1.7e-36 125.9 0.0 2.6e-36 125.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXL47001.1 - 1.5e-05 24.3 0.0 0.03 13.4 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KXL47001.1 - 0.00049 19.3 0.0 0.00072 18.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KXL47001.1 - 0.0005 20.2 0.1 0.0018 18.4 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXL47001.1 - 0.003 17.2 0.0 0.084 12.4 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXL47001.1 - 0.044 13.0 0.0 0.22 10.7 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXL47001.1 - 0.046 14.3 0.0 0.77 10.4 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXL47001.1 - 0.059 12.7 0.1 0.74 9.1 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KXL47001.1 - 0.089 11.6 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Aldedh PF00171.22 KXL47002.1 - 9.2e-149 495.9 0.0 1.1e-148 495.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TRF PF08558.10 KXL47003.1 - 0.0042 16.7 0.0 0.0086 15.7 0.0 1.5 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 KXL47003.1 - 0.013 15.7 0.0 0.029 14.6 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain UPF0016 PF01169.19 KXL47004.1 - 1.2e-42 144.0 25.5 4.2e-21 75.0 7.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF2070 PF09843.9 KXL47004.1 - 0.061 11.6 0.4 0.11 10.8 0.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) G3P_acyltransf PF02660.15 KXL47004.1 - 0.91 9.6 11.4 1.1 9.3 2.4 2.2 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase DUF3357 PF11837.8 KXL47004.1 - 4.5 7.8 8.8 6.5 7.3 0.1 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) RR_TM4-6 PF06459.12 KXL47005.1 - 6.4 6.5 7.7 5.2 6.8 4.2 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Aldo_ket_red PF00248.21 KXL47006.1 - 3e-61 207.2 0.0 4e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Epimerase_2 PF02350.19 KXL47006.1 - 0.054 12.3 0.0 0.085 11.7 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Oxidored-like PF09791.9 KXL47007.1 - 5.1e-25 86.9 2.7 8.5e-25 86.2 2.7 1.4 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Wtap PF17098.5 KXL47007.1 - 0.033 14.1 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 WTAP/Mum2p family TPP_enzyme_N PF02776.18 KXL47008.1 - 8.3e-37 126.4 0.4 1.4e-36 125.6 0.4 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KXL47008.1 - 1.8e-18 66.8 0.0 3.2e-17 62.7 0.0 2.6 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXL47008.1 - 4.1e-13 49.2 0.0 9.6e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain MFS_1 PF07690.16 KXL47009.1 - 5.8e-29 101.1 63.0 2.4e-24 85.9 34.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Tankyrase_bdg_C PF15327.6 KXL47011.1 - 0.027 14.9 0.6 0.058 13.8 0.1 1.8 2 0 0 2 2 2 0 Tankyrase binding protein C terminal domain FAM60A PF15396.6 KXL47012.1 - 0.0018 18.3 0.1 0.002 18.2 0.1 1.2 1 0 0 1 1 1 1 Protein Family FAM60A DUF1033 PF06279.11 KXL47012.1 - 0.084 13.1 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1033) Peptidase_S24 PF00717.23 KXL47013.1 - 2.8e-08 33.6 0.0 3.9e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Not1 PF04054.15 KXL47014.1 - 6.7e-103 344.4 0.0 1.8e-102 343.0 0.0 1.8 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 KXL47014.1 - 2.1e-88 295.5 4.3 4.2e-88 294.5 2.5 2.4 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 KXL47014.1 - 9.9e-48 161.8 4.4 2.9e-47 160.3 4.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 KXL47014.1 - 5e-36 123.7 0.0 1.6e-35 122.0 0.0 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 KXL47014.1 - 1.2e-34 119.6 0.4 1.2e-34 119.6 0.4 2.9 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 HEAT repeat DUF4487 PF14868.6 KXL47014.1 - 0.039 12.8 0.9 1.4 7.6 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4487) Mgm101p PF06420.12 KXL47015.1 - 7e-86 286.0 0.0 8.8e-86 285.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 BPL_N PF09825.9 KXL47016.1 - 2.1e-140 468.1 0.0 2.7e-140 467.7 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 KXL47016.1 - 2e-20 73.0 0.0 3.8e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 KXL47016.1 - 0.00012 21.9 0.0 0.00028 20.7 0.0 1.7 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain Glyco_hydro_42M PF08532.10 KXL47016.1 - 0.11 12.0 0.4 6.3 6.2 0.0 2.6 2 0 0 2 2 2 0 Beta-galactosidase trimerisation domain CHCH PF06747.13 KXL47017.1 - 3.3e-06 27.1 7.6 5.1e-06 26.5 7.6 1.3 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 KXL47017.1 - 0.0028 17.6 1.6 0.04 13.9 0.4 2.1 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 KXL47017.1 - 0.015 15.3 4.3 0.041 13.9 0.5 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 KXL47017.1 - 0.029 14.7 2.3 0.038 14.3 2.3 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) NAR2 PF16974.5 KXL47017.1 - 0.22 10.9 2.8 0.21 10.9 2.8 1.1 1 0 0 1 1 1 0 High-affinity nitrate transporter accessory Oxysterol_BP PF01237.18 KXL47018.1 - 2.5e-62 210.9 4.9 3.7e-60 203.7 4.9 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein DUF3752 PF12572.8 KXL47018.1 - 0.064 13.8 4.1 0.13 12.8 4.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) DUF676 PF05057.14 KXL47019.1 - 9.8e-40 136.4 0.0 1.3e-25 90.2 0.0 3.2 3 0 0 3 3 3 3 Putative serine esterase (DUF676) Lipase_3 PF01764.25 KXL47019.1 - 0.17 11.8 0.0 0.4 10.6 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase PF00702.26 KXL47020.1 - 1.1e-08 35.6 0.0 2.6e-08 34.4 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXL47020.1 - 1.6e-05 24.9 0.0 2.8e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 KXL47020.1 - 0.0013 18.8 0.0 0.39 10.8 0.0 2.8 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Smg8_Smg9 PF10220.9 KXL47020.1 - 0.22 9.8 0.0 0.3 9.4 0.0 1.1 1 0 0 1 1 1 0 Smg8_Smg9 PH PF00169.29 KXL47023.1 - 6.3e-07 29.9 0.1 1.2e-06 28.9 0.1 1.5 1 0 0 1 1 1 1 PH domain DUF5344 PF17279.2 KXL47023.1 - 0.15 12.7 0.3 9.1 6.9 0.1 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5344) Glyco_hydro_43 PF04616.14 KXL47024.1 - 6.1e-27 94.7 0.5 8.5e-27 94.2 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 XPG_I PF00867.18 KXL47025.1 - 1.4e-23 83.0 0.0 2.8e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KXL47025.1 - 4.7e-21 75.2 0.0 9.8e-21 74.1 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 KXL47025.1 - 1.5e-08 34.4 0.0 2.4e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 KXL47025.1 - 0.00022 21.7 0.0 0.00047 20.7 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 KXL47025.1 - 0.12 12.5 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Tma16 PF11176.8 KXL47026.1 - 8.5e-52 174.9 1.2 1e-51 174.6 1.2 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 Vir_act_alpha_C PF10400.9 KXL47026.1 - 0.27 12.0 2.6 3.7 8.3 0.3 2.4 2 1 0 2 2 2 0 Virulence activator alpha C-term HTH_32 PF13565.6 KXL47026.1 - 0.27 11.9 2.3 0.4 11.3 0.4 2.0 2 0 0 2 2 2 0 Homeodomain-like domain CRAL_TRIO PF00650.20 KXL47027.1 - 2.5e-25 89.1 0.0 3.7e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXL47027.1 - 1.9e-08 34.3 0.1 6.3e-08 32.7 0.0 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain YccV-like PF08755.11 KXL47028.1 - 5.4e-27 94.2 0.0 1.5e-26 92.8 0.0 1.8 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 KXL47028.1 - 3.2e-12 46.3 0.0 6.1e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 KXL47028.1 - 2.9e-08 33.5 1.1 7e-08 32.2 1.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXL47028.1 - 4.4e-07 29.6 0.1 1.1e-06 28.4 0.1 1.7 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 KXL47028.1 - 0.0076 16.8 0.5 0.017 15.6 0.5 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF4457 PF14652.6 KXL47029.1 - 0.11 11.7 0.0 0.22 10.7 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4457) HisKA PF00512.25 KXL47029.1 - 0.12 12.4 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain EzrA PF06160.12 KXL47029.1 - 0.13 10.4 0.0 0.17 10.0 0.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Glyco_hydro_16 PF00722.21 KXL47030.1 - 2.4e-35 121.6 1.5 3.9e-35 120.9 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Podoplanin PF05808.11 KXL47030.1 - 0.059 13.5 0.6 0.098 12.8 0.1 1.5 2 0 0 2 2 2 0 Podoplanin Leu_Phe_trans PF03588.14 KXL47030.1 - 0.092 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Leucyl/phenylalanyl-tRNA protein transferase MFS_1 PF07690.16 KXL47031.1 - 5.3e-25 88.1 23.1 5.3e-25 88.1 23.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL47031.1 - 0.00024 20.1 9.3 0.00024 20.1 9.3 2.6 2 1 0 3 3 3 1 Sugar (and other) transporter PTR2 PF00854.21 KXL47031.1 - 0.019 13.8 0.1 0.019 13.8 0.1 3.0 3 0 0 3 3 3 0 POT family CCSMST1 PF15013.6 KXL47031.1 - 0.8 9.9 2.4 1 9.6 0.1 2.4 3 0 0 3 3 3 0 CCSMST1 family Peptidase_C12 PF01088.21 KXL47032.1 - 1.6e-59 201.2 0.0 3.1e-59 200.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KXL47032.1 - 0.0018 18.2 0.0 0.0047 16.8 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases LtuB PF17455.2 KXL47032.1 - 0.13 12.9 0.1 0.28 11.8 0.1 1.5 1 0 0 1 1 1 0 Late transcription unit B Zn_clus PF00172.18 KXL47034.1 - 1.2e-05 25.3 14.8 3e-05 24.1 14.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 3HCDH_N PF02737.18 KXL47035.1 - 1.1e-24 87.3 0.0 1.7e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KXL47035.1 - 3.6e-22 78.8 0.0 6.5e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.19 KXL47035.1 - 0.026 13.9 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 KXL47035.1 - 0.035 14.6 0.0 0.052 14.1 0.0 1.5 1 1 0 1 1 1 0 XdhC Rossmann domain F420_oxidored PF03807.17 KXL47035.1 - 0.037 14.6 0.0 0.096 13.3 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 KXL47035.1 - 0.08 12.2 0.0 0.094 12.0 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KXL47035.1 - 0.1 13.2 0.0 0.18 12.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXL47035.1 - 0.15 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 KXL47035.1 - 0.2 11.6 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Esterase_phd PF10503.9 KXL47036.1 - 3.1e-12 46.5 5.8 1.9e-05 24.3 0.9 3.0 2 1 0 2 2 2 2 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KXL47036.1 - 0.00027 20.5 0.1 0.00048 19.7 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Cation_ATPase_C PF00689.21 KXL47037.1 - 1.6e-43 148.5 6.2 1.6e-43 148.5 6.2 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KXL47037.1 - 1.4e-39 135.4 4.3 6.4e-39 133.3 2.7 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KXL47037.1 - 4.4e-22 79.4 0.0 6.9e-11 42.8 0.0 3.6 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXL47037.1 - 2.1e-20 72.6 0.0 4e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KXL47037.1 - 4.7e-12 45.4 0.0 1e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXL47037.1 - 2.5e-06 27.4 0.4 5e-06 26.4 0.4 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase BUD22 PF09073.10 KXL47038.1 - 0.043 13.2 5.9 0.049 13.0 5.9 1.1 1 0 0 1 1 1 0 BUD22 SWIRM-assoc_2 PF16496.5 KXL47038.1 - 0.15 10.9 1.9 0.17 10.7 1.9 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Nop14 PF04147.12 KXL47038.1 - 0.99 7.5 7.8 1.1 7.4 7.8 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KXL47038.1 - 2.8 7.3 9.4 3.2 7.1 9.4 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 KXL47038.1 - 4.1 5.6 5.7 5 5.3 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.14 KXL47038.1 - 4.8 6.9 7.0 2.3 8.0 2.9 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CBS PF00571.28 KXL47040.1 - 6.4e-15 55.3 2.2 0.00012 22.4 0.0 5.3 5 0 0 5 5 5 3 CBS domain Sugar_tr PF00083.24 KXL47041.1 - 2.6e-41 141.9 19.2 3.4e-41 141.6 19.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL47041.1 - 3.5e-13 49.2 29.9 3.5e-13 49.2 29.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4129 PF13559.6 KXL47041.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) F-box-like PF12937.7 KXL47042.1 - 3.7e-09 36.3 0.0 7.9e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXL47042.1 - 0.0016 18.3 0.1 0.0033 17.3 0.1 1.5 1 0 0 1 1 1 1 F-box domain TPR_1 PF00515.28 KXL47042.1 - 0.017 14.9 0.1 0.43 10.5 0.2 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXL47042.1 - 0.09 12.9 2.0 0.5 10.6 0.3 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KXL47042.1 - 0.095 12.4 0.0 2.2 8.0 0.0 2.5 2 0 0 2 2 2 0 TPR repeat Vma12 PF11712.8 KXL47042.1 - 0.37 10.8 1.3 1.2 9.2 0.0 2.2 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Mito_carr PF00153.27 KXL47043.1 - 1.5e-60 201.1 1.5 2.4e-20 72.2 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXL47043.1 - 0.01 15.0 1.3 0.02 14.1 0.0 2.1 3 0 0 3 3 3 0 Gammaproteobacterial serine protease Vps51 PF08700.11 KXL47044.1 - 1.1e-27 95.9 0.3 2.3e-27 94.9 0.2 1.7 1 1 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.12 KXL47044.1 - 1.2e-05 24.2 1.1 1.5e-05 23.9 1.1 1.1 1 0 0 1 1 1 1 Dor1-like family COG2 PF06148.11 KXL47044.1 - 0.0008 19.5 0.2 0.0014 18.7 0.2 1.4 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 KXL47044.1 - 0.0013 18.9 0.7 0.0021 18.2 0.7 1.5 1 1 0 1 1 1 1 Golgi transport complex subunit 5 ZapB PF06005.12 KXL47044.1 - 0.32 11.5 5.1 1.2 9.6 4.7 2.3 1 1 0 1 1 1 0 Cell division protein ZapB Piwi PF02171.17 KXL47045.1 - 3.1e-82 276.2 0.0 4.3e-82 275.8 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 KXL47045.1 - 7.3e-20 71.2 0.4 1.3e-19 70.4 0.4 1.4 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 KXL47045.1 - 1.9e-18 67.4 0.0 4.2e-18 66.3 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KXL47045.1 - 4.5e-13 48.7 0.3 1.2e-12 47.3 0.3 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KXL47045.1 - 7.3e-12 45.4 0.0 1.7e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 KXL47045.1 - 4.5e-07 30.0 0.0 1.7e-06 28.1 0.0 2.0 1 0 0 1 1 1 1 Mid domain of argonaute DDE_1 PF03184.19 KXL47046.1 - 0.017 14.8 0.1 0.075 12.7 0.0 1.7 1 1 1 2 2 2 0 DDE superfamily endonuclease Fig1 PF12351.8 KXL47047.1 - 1.2e-57 194.9 2.7 1.2e-57 194.9 2.7 2.1 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 KXL47047.1 - 3.4e-07 30.1 6.7 5.6e-07 29.4 6.7 1.4 1 1 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.13 KXL47047.1 - 0.00052 19.2 2.7 0.00052 19.2 2.7 1.7 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) DUF2207 PF09972.9 KXL47047.1 - 0.047 12.5 11.5 0.26 10.0 1.8 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) PGG PF13962.6 KXL47047.1 - 0.57 10.0 8.2 0.031 14.1 2.2 2.1 2 1 0 2 2 2 0 Domain of unknown function DUF751 PF05421.11 KXL47047.1 - 0.83 10.4 0.1 0.83 10.4 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF751) FtsX PF02687.21 KXL47047.1 - 2.2 8.8 22.2 3.2 8.3 9.4 3.2 3 0 0 3 3 3 0 FtsX-like permease family Pox_A_type_inc PF04508.12 KXL47048.1 - 2.2 8.3 4.8 26 4.9 0.1 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat GTP_EFTU PF00009.27 KXL47049.1 - 9.4e-35 119.9 1.7 5.3e-33 114.2 1.7 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KXL47049.1 - 5.6e-24 84.3 0.0 2e-23 82.5 0.0 2.0 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 KXL47049.1 - 1e-08 35.3 0.0 2.2e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KXL47049.1 - 3.5e-05 23.3 0.0 6.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KXL47049.1 - 7.7e-05 22.7 0.1 0.0033 17.4 0.0 2.4 1 1 1 2 2 2 1 RsgA GTPase GTP_EFTU_D2 PF03144.25 KXL47049.1 - 0.0015 18.8 11.7 0.0072 16.7 1.4 3.5 3 0 0 3 3 3 2 Elongation factor Tu domain 2 FeoB_N PF02421.18 KXL47049.1 - 0.0024 17.4 0.1 0.0077 15.8 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 KXL47049.1 - 0.0085 15.5 0.0 0.017 14.5 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KXL47049.1 - 0.065 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 KXL47049.1 - 0.12 12.2 0.1 0.63 9.8 0.1 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RMI1_N PF08585.12 KXL47051.1 - 2e-62 210.8 0.0 2.4e-62 210.5 0.0 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein DUF1923 PF09083.10 KXL47051.1 - 0.066 12.9 0.2 0.13 12.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1923) DnaJ PF00226.31 KXL47052.1 - 3.2e-24 84.8 0.6 3.2e-24 84.8 0.6 2.0 2 0 0 2 2 2 1 DnaJ domain zf-met PF12874.7 KXL47052.1 - 1.1e-10 41.5 5.6 2.3e-08 34.1 2.8 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXL47052.1 - 2.2e-10 40.5 4.3 2.2e-10 40.5 4.3 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KXL47052.1 - 1.4e-06 28.5 0.9 0.0013 19.0 0.5 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KXL47052.1 - 7.3e-05 23.3 2.8 0.24 12.3 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KXL47052.1 - 0.0001 22.6 4.6 0.037 14.5 0.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type Actin_micro PF17003.5 KXL47052.1 - 0.012 14.8 1.0 0.063 12.4 0.2 2.1 2 0 0 2 2 2 0 Putative actin-like family zf-C2H2_6 PF13912.6 KXL47052.1 - 0.098 12.7 7.4 4 7.6 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger RPT PF13446.6 KXL47052.1 - 0.1 12.6 0.0 0.43 10.5 0.0 2.1 2 0 0 2 2 2 0 A repeated domain in UCH-protein Mog1 PF04603.12 KXL47053.1 - 1.9e-41 141.7 0.0 2.2e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein SprT-like PF10263.9 KXL47054.1 - 1.9e-37 127.5 1.6 4e-37 126.5 1.6 1.6 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 KXL47054.1 - 0.00023 21.0 3.8 0.00023 21.0 3.8 2.0 2 0 0 2 2 2 1 SprT-like zinc ribbon domain YdjO PF14169.6 KXL47054.1 - 0.14 11.9 2.3 0.29 10.9 0.7 2.1 2 0 0 2 2 2 0 Cold-inducible protein YdjO Zn-ribbon_8 PF09723.10 KXL47054.1 - 0.15 12.2 1.4 0.35 11.0 1.4 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Ndc1_Nup PF09531.10 KXL47054.1 - 0.17 10.5 1.5 0.27 9.9 1.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup UNC-50 PF05216.13 KXL47057.1 - 2.4e-89 298.7 12.6 2.8e-89 298.5 12.6 1.0 1 0 0 1 1 1 1 UNC-50 family Suf PF05843.14 KXL47058.1 - 1.8e-76 257.9 0.0 1.8e-76 257.9 0.0 4.5 6 0 0 6 6 6 1 Suppressor of forked protein (Suf) NRDE-2 PF08424.10 KXL47058.1 - 1.6e-05 24.2 0.1 0.0053 15.9 0.0 2.9 1 1 1 2 2 2 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 KXL47058.1 - 0.00021 21.9 3.5 0.0069 17.1 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat HAT PF02184.16 KXL47058.1 - 0.054 13.5 1.7 0.25 11.3 0.1 2.7 3 0 0 3 3 3 0 HAT (Half-A-TPR) repeat TPR_9 PF13371.6 KXL47058.1 - 0.12 12.5 0.1 0.6 10.3 0.1 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat THOC2_N PF16134.5 KXL47058.1 - 0.22 10.1 2.8 0.37 9.4 2.8 1.3 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus DUF3106 PF11304.8 KXL47058.1 - 7 7.2 10.1 0.97 9.9 2.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3106) HA2 PF04408.23 KXL47060.1 - 8.9e-22 77.4 0.0 2e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KXL47060.1 - 9.4e-14 51.5 0.0 2e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KXL47060.1 - 5.2e-12 46.1 0.0 1.2e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXL47060.1 - 1.5e-07 31.4 0.0 3.1e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KXL47060.1 - 8.8e-05 22.8 0.0 0.00027 21.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXL47060.1 - 0.00055 19.7 0.1 0.0016 18.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KXL47060.1 - 0.0024 18.2 0.0 0.0051 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KXL47060.1 - 0.0034 16.5 0.0 0.0061 15.7 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 KXL47060.1 - 0.027 14.2 0.0 0.069 12.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KXL47060.1 - 0.058 13.9 0.0 0.18 12.3 0.0 1.9 1 0 0 1 1 1 0 ABC transporter INCENP_ARK-bind PF03941.15 KXL47060.1 - 0.13 12.2 0.2 0.39 10.7 0.2 1.8 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region WLM PF08325.10 KXL47061.1 - 4.3e-26 92.2 1.8 4.3e-26 92.2 1.8 2.3 2 1 0 2 2 2 1 WLM domain DUF45 PF01863.17 KXL47061.1 - 6.5e-07 29.6 0.2 1.3e-06 28.6 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 zf-RanBP PF00641.18 KXL47061.1 - 0.001 18.3 8.8 0.005 16.1 2.5 2.8 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.7 KXL47061.1 - 0.84 9.7 8.6 2.2 8.4 8.6 1.7 1 0 0 1 1 1 0 Double zinc ribbon Glyco_hydro_47 PF01532.20 KXL47062.1 - 1.8e-165 551.3 0.0 2.1e-165 551.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 tRNA-synt_2 PF00152.20 KXL47064.1 - 9.4e-75 251.6 0.0 1.2e-74 251.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KXL47064.1 - 2.1e-09 37.2 0.0 3.5e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KXL47064.1 - 0.0083 15.6 0.2 2.7 7.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Vps23_core PF09454.10 KXL47064.1 - 0.039 13.9 0.0 4.3 7.4 0.0 2.9 3 0 0 3 3 3 0 Vps23 core domain AAA PF00004.29 KXL47065.1 - 3.4e-36 124.6 0.0 5.7e-36 123.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXL47065.1 - 9.3e-10 38.2 0.0 2.4e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 KXL47065.1 - 4.3e-08 33.0 0.0 4.3e-06 26.6 0.0 3.0 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_16 PF13191.6 KXL47065.1 - 9.4e-05 22.8 2.0 0.0053 17.2 0.1 3.4 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KXL47065.1 - 0.00015 22.1 0.0 0.002 18.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KXL47065.1 - 0.00016 21.4 0.0 0.00029 20.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KXL47065.1 - 0.0016 18.5 0.0 0.0038 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KXL47065.1 - 0.0025 17.1 0.0 0.0046 16.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 KXL47065.1 - 0.0026 17.5 0.0 0.0047 16.7 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KXL47065.1 - 0.0059 16.0 0.1 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 KXL47065.1 - 0.019 14.1 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 KXL47065.1 - 0.028 14.0 0.0 0.2 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KXL47065.1 - 0.034 14.3 0.0 0.073 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXL47065.1 - 0.071 13.7 0.0 0.24 12.0 0.0 1.9 2 1 0 2 2 1 0 AAA domain AAA_24 PF13479.6 KXL47065.1 - 0.097 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 KXL47065.1 - 0.1 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 KXL47065.1 - 0.13 12.5 2.9 0.7 10.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 KXL47065.1 - 0.16 12.0 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXL47065.1 - 0.19 11.6 0.0 0.42 10.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain SYS1 PF09801.9 KXL47066.1 - 4.6e-51 172.8 10.9 5.4e-51 172.5 10.9 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Tim17 PF02466.19 KXL47067.1 - 1.3e-06 28.7 8.2 2.2e-06 28.0 7.6 1.8 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family NDUF_C2 PF06374.11 KXL47067.1 - 0.17 12.0 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) TBCC PF07986.12 KXL47068.1 - 3.7e-23 81.5 0.0 8.9e-22 77.1 0.0 2.3 1 1 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 KXL47068.1 - 0.0035 17.8 0.0 0.0084 16.5 0.0 1.6 1 1 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain 4HBT_2 PF13279.6 KXL47069.1 - 4.4e-24 85.3 0.0 6.5e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 KXL47069.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Acyl-ACP thioesterase Macoilin PF09726.9 KXL47070.1 - 0.045 12.3 20.9 0.014 14.0 10.2 2.2 1 1 1 2 2 2 0 Macoilin family HxlR PF01638.17 KXL47070.1 - 0.15 11.9 0.5 0.31 10.9 0.5 1.4 1 0 0 1 1 1 0 HxlR-like helix-turn-helix PgaD PF13994.6 KXL47070.1 - 0.69 10.0 2.9 1.1 9.3 0.8 2.3 3 0 0 3 3 3 0 PgaD-like protein Methyltransf_2 PF00891.18 KXL47075.1 - 2.9e-25 88.8 0.0 4.4e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 KXL47075.1 - 0.0064 16.5 0.1 0.016 15.2 0.1 1.7 1 0 0 1 1 1 1 Dimerisation domain Dimerisation2 PF16864.5 KXL47075.1 - 0.013 15.4 0.1 0.024 14.6 0.1 1.4 1 0 0 1 1 1 0 Dimerisation domain HTH_20 PF12840.7 KXL47075.1 - 0.027 14.5 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Rrf2 PF02082.20 KXL47075.1 - 0.068 13.5 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator Catalase PF00199.19 KXL47076.1 - 1.6e-174 580.5 0.0 1.9e-174 580.2 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KXL47076.1 - 4.1e-17 62.2 0.0 1.2e-16 60.7 0.0 1.9 1 0 0 1 1 1 1 Catalase-related immune-responsive Bot1p PF12298.8 KXL47077.1 - 1.1e-46 159.2 1.0 1.1e-46 159.2 1.0 1.6 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein RHH_5 PF07878.11 KXL47077.1 - 0.01 15.7 0.0 0.029 14.2 0.0 1.7 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 DUF2526 PF10735.9 KXL47077.1 - 7.1 6.9 11.6 0.4 10.9 3.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2526) Acyltransferase PF01553.21 KXL47078.1 - 3.7e-31 107.6 0.0 5.6e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Poly_export PF02563.16 KXL47078.1 - 0.041 14.1 0.0 0.073 13.3 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis/export protein adh_short PF00106.25 KXL47079.1 - 6.7e-44 149.7 0.3 8e-44 149.4 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL47079.1 - 1.7e-42 145.6 1.4 1.9e-42 145.4 1.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL47079.1 - 6e-11 42.6 0.5 8.3e-11 42.1 0.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL47079.1 - 0.0036 16.8 0.0 0.0053 16.3 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KXL47079.1 - 0.022 15.0 0.1 0.038 14.3 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 KXL47079.1 - 0.057 12.8 0.1 0.082 12.3 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase TTc_toxin_rep PF18807.1 KXL47079.1 - 0.082 12.7 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Tripartite Tc toxins repeat ACC_central PF08326.12 KXL47081.1 - 8.6e-274 910.3 0.0 1.1e-273 910.0 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 KXL47081.1 - 7.6e-186 618.5 0.0 1.1e-185 618.1 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KXL47081.1 - 3.4e-52 177.0 0.1 6.4e-52 176.1 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KXL47081.1 - 1.3e-27 96.5 0.1 3e-27 95.4 0.1 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KXL47081.1 - 1e-23 83.4 0.0 4.5e-21 75.0 0.0 3.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KXL47081.1 - 1.1e-16 60.4 0.1 3.1e-16 59.0 0.1 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KXL47081.1 - 5.7e-05 22.8 0.1 0.00064 19.3 0.0 2.5 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KXL47081.1 - 0.0014 18.2 0.1 0.0037 16.9 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KXL47081.1 - 0.0016 18.5 0.0 0.0051 16.9 0.0 1.9 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 KXL47081.1 - 0.0035 17.1 0.0 0.011 15.5 0.0 1.8 1 0 0 1 1 1 1 Biotin-lipoyl like GxGYxYP_N PF16216.5 KXL47081.1 - 0.019 15.2 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal PSD5 PF07637.11 KXL47081.1 - 0.84 10.0 3.8 0.43 11.0 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1595) NUDE_C PF04880.13 KXL47082.1 - 3.7e-44 151.3 6.0 3.7e-44 151.3 6.0 4.2 3 1 1 4 4 2 1 NUDE protein, C-terminal conserved region YppF PF14178.6 KXL47082.1 - 0.048 13.5 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 YppF-like protein Macoilin PF09726.9 KXL47082.1 - 1 7.8 14.0 2.2 6.7 14.0 1.5 1 0 0 1 1 1 0 Macoilin family YlqD PF11068.8 KXL47082.1 - 1.2 9.5 23.0 0.18 12.2 13.9 3.1 3 1 1 4 4 4 0 YlqD protein DUF745 PF05335.13 KXL47082.1 - 1.2 8.8 17.0 0.34 10.6 14.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF745) FemAB PF02388.16 KXL47082.1 - 1.5 7.7 10.6 2.3 7.0 10.6 1.2 1 0 0 1 1 1 0 FemAB family Tropomyosin_1 PF12718.7 KXL47082.1 - 1.5 9.0 36.0 0.79 9.9 26.4 3.4 2 1 1 3 3 3 0 Tropomyosin like Prefoldin_2 PF01920.20 KXL47082.1 - 2.8 7.9 29.1 0.11 12.5 8.4 5.0 2 1 3 5 5 5 0 Prefoldin subunit DUF3584 PF12128.8 KXL47082.1 - 3.7 5.0 23.5 21 2.4 24.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) ERM PF00769.19 KXL47082.1 - 6.2 6.6 37.9 1.1 9.1 15.6 2.5 2 1 1 3 3 3 0 Ezrin/radixin/moesin family HMMR_N PF15905.5 KXL47082.1 - 8 5.8 30.5 27 4.1 29.4 2.1 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal IFT57 PF10498.9 KXL47082.1 - 8.4 5.2 20.6 0.44 9.5 13.5 1.9 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 TPR_MLP1_2 PF07926.12 KXL47082.1 - 8.8 6.4 33.3 6.7 6.8 20.6 4.0 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein WD40 PF00400.32 KXL47083.1 - 2.6e-25 88.2 8.4 2.3e-08 34.5 0.0 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL47083.1 - 5.5e-08 33.0 0.0 0.017 15.4 0.0 3.7 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXL47083.1 - 0.00049 18.9 0.0 0.0093 14.7 0.0 2.6 3 0 0 3 3 3 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KXL47083.1 - 0.0028 16.7 0.1 0.023 13.7 0.0 2.4 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein dsrm PF00035.26 KXL47083.1 - 0.16 12.7 0.0 0.32 11.7 0.0 1.5 1 0 0 1 1 1 0 Double-stranded RNA binding motif RRM_1 PF00076.22 KXL47085.1 - 7.2e-18 64.2 0.0 4.4e-13 48.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXL47085.1 - 0.0025 17.7 0.0 0.0046 16.8 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif CAP_N PF01213.19 KXL47086.1 - 2 7.8 5.1 2.4 7.5 5.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal IMS PF00817.20 KXL47090.1 - 1e-42 145.6 0.0 1.7e-42 144.9 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family zf_UBZ PF18439.1 KXL47090.1 - 1.3e-14 53.5 1.4 2.6e-14 52.5 1.4 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 KXL47090.1 - 2.4e-12 47.6 0.0 9.1e-12 45.7 0.0 2.0 3 0 0 3 3 3 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KXL47090.1 - 0.014 15.7 0.0 0.029 14.7 0.0 1.6 1 0 0 1 1 1 0 IMS family HHH motif DUF2052 PF09747.9 KXL47091.1 - 1e-21 78.0 20.8 6.7e-11 42.7 0.8 2.6 1 1 2 3 3 3 2 Coiled-coil domain containing protein (DUF2052) MFS_1 PF07690.16 KXL47093.1 - 9.4e-22 77.4 23.0 1.3e-21 77.0 23.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.8 KXL47093.1 - 0.002 16.8 3.9 0.0038 15.9 3.9 1.5 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like ATP-synt_C PF00137.21 KXL47094.1 - 2.5e-28 98.2 36.1 6.9e-18 64.7 12.1 2.1 2 0 0 2 2 2 2 ATP synthase subunit C CNH PF00780.22 KXL47095.1 - 4.6e-67 226.5 0.0 1.2e-66 225.2 0.0 1.6 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 KXL47095.1 - 2.7e-44 150.5 0.0 7.9e-44 149.0 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KXL47095.1 - 3.6e-38 131.6 0.1 6.7e-38 130.7 0.1 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 KXL47095.1 - 3.4e-14 52.7 0.0 6.8e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Gly_transf_sug PF04488.15 KXL47097.1 - 4.1e-13 49.8 0.0 1.3e-12 48.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif HeLo PF14479.6 KXL47098.1 - 5.7e-06 26.3 1.3 0.0025 17.7 0.0 3.0 3 0 0 3 3 3 2 Prion-inhibition and propagation adh_short_C2 PF13561.6 KXL47099.1 - 6.9e-56 189.4 0.1 9.6e-56 189.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL47099.1 - 2.6e-38 131.4 0.1 3.6e-38 131.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL47099.1 - 7.1e-13 48.9 0.3 1e-12 48.3 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL47099.1 - 0.013 15.0 0.1 0.035 13.6 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXL47099.1 - 0.05 13.0 0.0 4.5 6.6 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KXL47100.1 - 3.1e-10 39.8 0.6 6.7e-10 38.7 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL47100.1 - 2.6e-06 27.2 0.1 1.1e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL47100.1 - 0.0089 16.0 0.1 0.019 14.9 0.0 1.5 2 0 0 2 2 2 1 KR domain Glyco_hydro_38N PF01074.22 KXL47101.1 - 1.5e-81 273.9 0.2 3e-81 272.9 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KXL47101.1 - 4.1e-55 187.2 0.1 6.8e-55 186.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KXL47101.1 - 1e-26 92.9 0.0 2.2e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KXL47101.1 - 1.6e-05 25.0 0.0 4e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Sugar_tr PF00083.24 KXL47102.1 - 3.2e-84 283.4 19.1 3.7e-84 283.2 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL47102.1 - 2.7e-40 138.4 40.5 2.9e-32 112.0 22.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXL47102.1 - 1.8e-05 23.4 0.5 1.8e-05 23.4 0.5 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF543 PF04418.12 KXL47102.1 - 0.47 10.5 3.4 1.8 8.6 0.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF543) MFS_1 PF07690.16 KXL47103.1 - 1.5e-16 60.3 69.6 8.2e-14 51.3 32.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NDT80_PhoG PF05224.12 KXL47104.1 - 9.1e-37 127.1 0.3 2.5e-36 125.7 0.3 1.7 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Alpha-amylase PF00128.24 KXL47105.1 - 3e-117 392.0 0.2 5e-117 391.2 0.2 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KXL47105.1 - 2.2e-06 27.7 0.0 1.1e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 Maltogenic Amylase, C-terminal domain Glyco_hydro_114 PF03537.13 KXL47105.1 - 0.062 12.6 0.2 0.43 9.8 0.0 2.4 3 0 0 3 3 3 0 Glycoside-hydrolase family GH114 Glyco_hydro_42C PF08533.10 KXL47105.1 - 0.066 12.9 0.0 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 Beta-galactosidase C-terminal domain Zn_clus PF00172.18 KXL47106.1 - 1e-08 35.1 12.4 2.6e-08 33.8 12.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3950 PF13132.6 KXL47106.1 - 0.26 11.1 0.0 0.26 11.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3950) Metallophos PF00149.28 KXL47107.1 - 1.1e-13 52.1 3.4 2.2e-13 51.2 3.4 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXL47107.1 - 6.4e-07 29.7 0.0 1.8e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RCC1 PF00415.18 KXL47108.1 - 1.6e-52 175.9 7.4 2e-10 41.1 0.0 8.6 7 2 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KXL47108.1 - 4.3e-43 144.3 27.0 1.5e-08 34.2 0.1 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Presenilin PF01080.17 KXL47108.1 - 7.8 5.1 5.4 11 4.7 5.4 1.2 1 0 0 1 1 1 0 Presenilin Cyclase PF04199.13 KXL47109.1 - 1.6e-14 54.3 0.0 2.3e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Cation_efflux PF01545.21 KXL47110.1 - 6e-08 32.7 13.8 8.7e-08 32.1 13.8 1.2 1 0 0 1 1 1 1 Cation efflux family PIG-Y PF15159.6 KXL47111.1 - 2.2e-21 76.5 6.1 3.6e-21 75.9 6.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Abhydrolase_3 PF07859.13 KXL47112.1 - 5e-41 140.9 0.1 2e-40 138.9 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXL47112.1 - 1.2e-05 24.4 0.0 2.6e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Steryl acetyl hydrolase DAO PF01266.24 KXL47112.1 - 0.085 12.4 0.0 0.18 11.3 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase CHZ PF09649.10 KXL47113.1 - 5.6e-05 22.5 2.4 0.00011 21.6 2.4 1.4 1 0 0 1 1 1 1 Histone chaperone domain CHZ zf-PARP PF00645.18 KXL47114.1 - 1.4e-19 70.7 0.2 1.4e-19 70.7 0.2 2.1 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region RD3 PF14473.6 KXL47115.1 - 0.081 12.8 0.0 0.32 10.8 0.0 2.0 1 0 0 1 1 1 0 RD3 protein DPBB_1 PF03330.18 KXL47116.1 - 0.036 14.4 0.8 0.07 13.4 0.7 1.6 1 1 0 1 1 1 0 Lytic transglycolase Transferrin PF00405.17 KXL47116.1 - 0.1 11.8 0.4 0.17 11.0 0.1 1.4 1 1 0 1 1 1 0 Transferrin FANCL_C PF11793.8 KXL47117.1 - 2.2e-06 27.8 3.0 4.2e-06 26.8 3.0 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.7 KXL47117.1 - 1e-05 25.6 5.7 1.9e-05 24.7 5.7 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KXL47117.1 - 0.27 11.6 9.6 0.6 10.5 9.6 1.6 1 1 0 1 1 1 0 Ring finger domain SNF2_N PF00176.23 KXL47118.1 - 9.7e-67 225.1 0.0 1.9e-66 224.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXL47118.1 - 1.2e-19 70.6 0.0 5.1e-19 68.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL47118.1 - 9.3e-08 32.3 0.5 5.7e-06 26.4 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit TFIIF_beta PF02270.15 KXL47118.1 - 0.0066 16.6 0.0 0.018 15.2 0.0 1.7 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain Snapin_Pallidin PF14712.6 KXL47118.1 - 0.021 15.2 9.9 0.016 15.6 5.9 2.5 1 1 1 2 2 2 0 Snapin/Pallidin KxDL PF10241.9 KXL47118.1 - 0.13 12.6 4.9 0.46 10.8 4.9 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein Lactamase_B_2 PF12706.7 KXL47121.1 - 1e-28 100.2 0.0 2.2e-27 95.9 0.0 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXL47121.1 - 2.9e-12 46.8 0.0 8.5e-12 45.3 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KXL47121.1 - 2.1e-05 24.7 0.3 0.0006 19.9 0.1 2.5 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily UQ_con PF00179.26 KXL47122.1 - 3.5e-19 68.8 0.0 5.3e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ribosomal_S11 PF00411.19 KXL47123.1 - 1.4e-46 157.4 1.4 1.8e-46 157.1 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 PDH PF02153.17 KXL47124.1 - 9.8e-14 51.0 0.0 1.7e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 KXL47124.1 - 1.5e-06 28.5 0.1 2.9e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KXL47124.1 - 2.8e-06 27.8 0.0 6.6e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KXL47124.1 - 0.00083 18.8 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KXL47124.1 - 0.0028 17.3 0.0 0.005 16.5 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KXL47124.1 - 0.0064 16.4 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 KXL47124.1 - 0.11 12.1 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain XdhC_C PF13478.6 KXL47124.1 - 0.16 12.5 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain TFR_dimer PF04253.15 KXL47125.1 - 4.6e-34 117.1 0.0 7.6e-34 116.4 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KXL47125.1 - 3.9e-21 75.6 0.0 7.8e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KXL47125.1 - 1.3e-07 31.5 0.0 3.1e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 PA domain Glyoxalase PF00903.25 KXL47126.1 - 2.3e-10 40.7 0.2 3.8e-10 40.0 0.2 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF5025 PF16428.5 KXL47126.1 - 0.058 13.6 0.0 0.08 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5025) Glyoxalase_6 PF18029.1 KXL47126.1 - 0.11 13.3 0.0 0.22 12.3 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase-like domain Cyto_heme_lyase PF01265.17 KXL47127.1 - 4.6e-120 400.6 0.3 6e-120 400.2 0.3 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase GFO_IDH_MocA PF01408.22 KXL47128.1 - 8.2e-09 36.3 0.0 2.3e-08 34.9 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Zn_clus PF00172.18 KXL47128.1 - 1.3e-08 34.8 8.5 1.3e-08 34.8 8.5 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GFO_IDH_MocA_C PF02894.17 KXL47128.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain IBP39 PF11422.8 KXL47129.1 - 0.0035 17.1 1.2 2 8.2 0.2 2.7 2 1 1 3 3 3 2 Initiator binding protein 39 kDa DnaI_N PF07319.11 KXL47129.1 - 0.0059 17.3 3.6 0.0059 17.3 3.6 2.5 2 0 0 2 2 2 1 Primosomal protein DnaI N-terminus XH PF03469.14 KXL47129.1 - 0.006 16.5 7.1 0.084 12.8 0.2 3.7 3 2 0 3 3 3 1 XH domain Activator-TraM PF11657.8 KXL47129.1 - 0.14 12.0 1.9 0.23 11.3 0.1 2.3 2 0 0 2 2 2 0 Transcriptional activator TraM DUF2232 PF09991.9 KXL47129.1 - 0.24 10.5 0.6 3.4 6.8 0.1 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) DUF948 PF06103.11 KXL47129.1 - 0.37 11.1 11.8 0.6 10.4 0.1 4.8 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) ACP_PD PF04336.12 KXL47129.1 - 0.5 10.8 2.9 3 8.3 0.0 3.5 3 2 1 4 4 4 0 Acyl carrier protein phosphodiesterase Bacteriocin_IIc PF10439.9 KXL47129.1 - 0.56 10.4 3.5 1 9.5 3.5 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide TMCCDC2 PF15844.5 KXL47129.1 - 0.67 9.9 5.3 0.44 10.5 2.6 2.1 2 0 0 2 2 2 0 Transmembrane and coiled-coil domain-containing protein 2 Tugs PF17840.1 KXL47129.1 - 1 9.6 6.1 0.88 9.8 0.1 3.1 3 0 0 3 3 3 0 Tethering Ubl4a to BAGS domain Prominin PF05478.11 KXL47129.1 - 1.3 6.9 16.7 0.084 10.8 0.1 2.9 1 1 0 2 2 2 0 Prominin CarD_CdnL_TRCF PF02559.16 KXL47129.1 - 1.7 9.4 9.2 21 5.9 0.4 4.6 3 2 2 5 5 5 0 CarD-like/TRCF domain DUF2937 PF11157.8 KXL47129.1 - 3.1 7.5 8.3 1.6 8.4 1.1 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2937) DAP_B PF07930.12 KXL47130.1 - 3.2e-65 219.5 0.0 4.4e-65 219.1 0.0 1.2 1 0 0 1 1 1 1 D-aminopeptidase, domain B Beta-lactamase PF00144.24 KXL47130.1 - 1.2e-47 162.8 0.0 1.6e-47 162.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase GFA PF04828.14 KXL47131.1 - 0.0088 16.4 12.2 0.04 14.2 0.3 2.9 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme Lipase_GDSL_2 PF13472.6 KXL47132.1 - 2.6e-17 63.8 0.2 4.2e-17 63.1 0.2 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXL47132.1 - 5.9e-05 23.1 0.0 9.7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Sugar_tr PF00083.24 KXL47134.1 - 6.6e-101 338.4 33.4 7.6e-101 338.2 33.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL47134.1 - 2.8e-26 92.3 35.6 2.8e-26 92.3 35.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1385 PF07136.11 KXL47134.1 - 0.48 9.7 3.9 22 4.2 2.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1385) YtpI PF14007.6 KXL47134.1 - 5.9 7.1 8.0 1.6 9.0 0.4 3.4 3 0 0 3 3 3 0 YtpI-like protein AAA_12 PF13087.6 KXL47135.1 - 5.3e-38 130.7 0.0 1.3e-37 129.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KXL47135.1 - 2.9e-22 79.7 0.2 1.7e-21 77.2 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXL47135.1 - 7.1e-11 42.6 0.0 1.1e-09 38.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXL47135.1 - 2.3e-08 34.0 0.1 1.5e-06 28.1 0.0 3.2 4 0 0 4 4 4 1 AAA domain Viral_helicase1 PF01443.18 KXL47135.1 - 0.00025 20.9 0.0 0.12 12.1 0.0 2.9 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 KXL47135.1 - 0.0017 17.8 0.0 0.0037 16.8 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein ResIII PF04851.15 KXL47135.1 - 0.012 15.6 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KXL47135.1 - 0.042 13.4 0.0 0.16 11.5 0.0 2.0 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 KXL47135.1 - 0.049 14.0 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DEAD PF00270.29 KXL47135.1 - 0.089 12.6 0.1 0.2 11.4 0.0 1.6 2 0 0 2 2 2 0 DEAD/DEAH box helicase Arg_decarbox_C PF17944.1 KXL47137.1 - 0.14 12.7 0.0 0.38 11.3 0.0 1.8 1 0 0 1 1 1 0 Arginine decarboxylase C-terminal helical extension CPSase_L_D2 PF02786.17 KXL47138.1 - 3.8e-74 248.7 0.0 6.1e-74 248.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KXL47138.1 - 2.4e-38 130.5 0.0 4.8e-38 129.6 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KXL47138.1 - 1.2e-36 125.6 0.0 2.5e-36 124.5 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 KXL47138.1 - 6.5e-17 61.1 0.5 1.3e-16 60.1 0.5 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KXL47138.1 - 1.1e-09 38.2 0.0 2.3e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KXL47138.1 - 1.5e-08 34.4 0.0 3.6e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 KXL47138.1 - 1.8e-07 30.8 0.0 0.005 16.6 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 KXL47138.1 - 0.00017 21.7 0.0 0.00035 20.7 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 KXL47138.1 - 0.0015 19.2 0.0 1.6 9.4 0.0 2.6 2 0 0 2 2 2 2 HlyD family secretion protein RimK PF08443.11 KXL47138.1 - 0.021 14.4 0.0 0.07 12.7 0.0 2.0 1 1 0 1 1 1 0 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.6 KXL47138.1 - 0.04 13.1 0.0 0.081 12.2 0.0 1.4 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp GARS_A PF01071.19 KXL47138.1 - 0.054 13.3 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GCV_H PF01597.19 KXL47138.1 - 0.12 12.3 0.1 0.29 11.0 0.1 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein ATP-grasp_4 PF13535.6 KXL47138.1 - 0.13 11.8 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Asp PF00026.23 KXL47139.1 - 1.1e-68 232.0 1.7 2.5e-68 230.8 1.7 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXL47139.1 - 1.1e-12 48.5 0.0 1.3e-06 28.8 0.2 2.6 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KXL47139.1 - 3.8e-05 23.5 0.0 0.00015 21.6 0.0 2.0 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KXL47139.1 - 0.019 15.6 1.4 4.7 7.9 0.0 3.7 4 1 0 4 4 4 0 Aspartyl protease gag-asp_proteas PF13975.6 KXL47139.1 - 0.14 12.8 0.3 47 4.6 0.0 3.6 3 1 0 3 3 3 0 gag-polyprotein putative aspartyl protease Sugar_tr PF00083.24 KXL47140.1 - 7.6e-43 147.0 18.5 1.1e-42 146.4 18.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL47140.1 - 9.3e-18 64.3 27.6 9.3e-18 64.3 27.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2759 PF10958.8 KXL47140.1 - 2.4 8.0 10.3 0.11 12.2 0.4 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2759) Lactamase_B_2 PF12706.7 KXL47141.1 - 2.3e-20 73.0 0.0 1.4e-17 63.9 0.0 2.3 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXL47141.1 - 0.00045 20.1 0.0 0.0012 18.8 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Sugar_tr PF00083.24 KXL47142.1 - 2.3e-85 287.2 20.0 2.7e-85 286.9 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL47142.1 - 7.2e-44 150.1 44.6 6.5e-34 117.4 25.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXL47142.1 - 0.00011 20.7 1.8 0.00018 20.1 1.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KXL47142.1 - 0.25 10.2 15.4 0.8 8.5 1.7 2.3 2 0 0 2 2 2 0 MFS_1 like family BNR_4 PF15892.5 KXL47143.1 - 5.1e-73 245.8 6.4 6.1e-73 245.5 6.4 1.1 1 0 0 1 1 1 1 BNR repeat-containing family member DUF2264 PF10022.9 KXL47144.1 - 7.9e-124 413.3 0.8 9.9e-124 413.0 0.8 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Glyco_hydro_88 PF07470.13 KXL47145.1 - 3.3e-11 42.9 0.4 8.6e-11 41.5 0.4 1.9 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 Fungal_trans PF04082.18 KXL47146.1 - 3.1e-15 55.9 0.0 5.6e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL47146.1 - 6.3e-09 35.8 11.9 1.1e-08 35.0 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HERV-K_REC PF15695.5 KXL47146.1 - 0.084 12.9 1.3 14 5.8 0.0 2.5 2 0 0 2 2 2 0 Rec (regulator of expression encoded by corf) of HERV-K-113 Ank_5 PF13857.6 KXL47147.1 - 8e-20 70.7 0.1 2.5e-12 46.7 0.1 5.9 5 1 1 6 6 6 2 Ankyrin repeats (many copies) VPS9 PF02204.18 KXL47147.1 - 1.8e-15 57.1 0.1 6.6e-15 55.2 0.0 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.7 KXL47147.1 - 6.5e-14 52.3 0.1 7.3e-06 26.5 0.0 4.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXL47147.1 - 2.3e-07 30.6 0.1 0.94 10.2 0.0 5.8 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 KXL47147.1 - 8.9e-06 26.2 0.0 0.17 12.5 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KXL47147.1 - 0.0006 20.1 0.7 28 5.4 0.4 4.8 5 0 0 5 5 5 0 Ankyrin repeat PX PF00787.24 KXL47147.1 - 0.047 13.7 0.0 0.16 11.9 0.0 1.9 1 0 0 1 1 1 0 PX domain PriCT_1 PF08708.11 KXL47147.1 - 0.15 11.8 0.3 3.6 7.4 0.0 2.9 2 0 0 2 2 2 0 Primase C terminal 1 (PriCT-1) YchF-GTPase_C PF06071.13 KXL47148.1 - 2.5e-33 114.1 0.1 7.3e-33 112.6 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KXL47148.1 - 1.9e-15 57.0 0.0 5.6e-15 55.4 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 KXL47148.1 - 0.00075 19.5 0.1 0.0019 18.2 0.1 1.7 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KXL47148.1 - 0.0033 17.0 0.0 0.0071 15.9 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Halogen_Hydrol PF10112.9 KXL47149.1 - 0.053 13.5 0.1 3.7 7.5 0.0 2.1 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein ATP1G1_PLM_MAT8 PF02038.16 KXL47149.1 - 0.075 12.5 1.0 0.15 11.5 1.0 1.5 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family Aldo_ket_red PF00248.21 KXL47150.1 - 3.5e-64 216.8 0.0 3.9e-64 216.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-H2C2_2 PF13465.6 KXL47151.1 - 1.7e-08 34.5 11.3 4e-07 30.2 1.0 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KXL47151.1 - 2.3e-06 27.7 9.9 2.9e-05 24.3 0.2 4.2 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KXL47151.1 - 3.1e-06 27.0 0.9 0.018 15.1 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KXL47151.1 - 0.026 15.4 11.8 0.032 15.0 0.2 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger FOXP-CC PF16159.5 KXL47151.1 - 0.037 14.7 0.1 0.037 14.7 0.1 4.5 4 1 1 5 5 5 0 FOXP coiled-coil domain zf-Di19 PF05605.12 KXL47151.1 - 0.31 11.4 5.7 0.89 9.9 1.4 2.5 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding NRBF2 PF08961.10 KXL47151.1 - 0.39 10.3 6.3 1.6 8.3 0.2 2.4 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator Zap1_zf2 PF18217.1 KXL47151.1 - 0.86 9.7 6.8 0.45 10.5 0.3 2.5 2 0 0 2 2 2 0 Zap1 zinc finger 2 HALZ PF02183.18 KXL47151.1 - 1.4 9.2 7.8 11 6.3 2.5 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper zf-H2C2_5 PF13909.6 KXL47151.1 - 2.1 8.2 5.9 3.3 7.5 0.0 3.4 4 0 0 4 4 4 0 C2H2-type zinc-finger domain Gal4_dimer PF03902.13 KXL47152.1 - 5.5e-06 26.4 0.4 1.3e-05 25.2 0.4 1.6 1 0 0 1 1 1 1 Gal4-like dimerisation domain Zn_clus PF00172.18 KXL47152.1 - 0.057 13.5 4.6 0.16 12.2 4.6 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KXL47153.1 - 3.6e-30 105.2 0.0 4.8e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL47153.1 - 0.00077 18.5 7.1 0.00095 18.2 2.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PAP2 PF01569.21 KXL47154.1 - 2.1e-26 92.3 3.1 2.1e-26 92.3 3.1 2.2 2 1 0 2 2 2 1 PAP2 superfamily DUF389 PF04087.14 KXL47154.1 - 0.059 13.4 1.6 0.57 10.2 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF389) FTZ PF03867.14 KXL47158.1 - 0.021 14.4 0.9 0.055 13.0 0.9 1.7 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region Thiamine_BP PF01910.17 KXL47159.1 - 3.8e-32 110.1 0.0 4.3e-32 109.9 0.0 1.0 1 0 0 1 1 1 1 Thiamine-binding protein Retro_M PF02813.14 KXL47159.1 - 0.0044 17.4 0.1 0.0062 16.9 0.1 1.3 1 0 0 1 1 1 1 Retroviral M domain ATP_Ca_trans_C PF12424.8 KXL47159.1 - 0.086 13.3 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 Plasma membrane calcium transporter ATPase C terminal Ins_P5_2-kin PF06090.12 KXL47160.1 - 7.5e-45 153.8 2.1 1.3e-44 153.0 2.1 1.4 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase TRAM_LAG1_CLN8 PF03798.16 KXL47161.1 - 5.8e-39 133.9 19.1 8.9e-39 133.3 19.1 1.3 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 KXL47161.1 - 3.7e-14 52.1 2.1 1.2e-13 50.5 0.0 2.5 2 0 0 2 2 2 1 TRAM1-like protein Annexin PF00191.20 KXL47162.1 - 5.9e-74 244.1 5.1 4e-19 68.4 0.2 4.1 4 0 0 4 4 4 4 Annexin Acetyltransf_11 PF13720.6 KXL47162.1 - 0.012 16.1 2.2 16 6.0 0.2 3.5 2 1 1 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 PID PF00640.23 KXL47162.1 - 0.079 13.0 0.1 0.2 11.7 0.1 1.5 1 1 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) DUF5638 PF18688.1 KXL47162.1 - 0.082 13.2 0.8 3.6 7.9 0.1 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5638) DUF3574 PF12098.8 KXL47162.1 - 0.13 12.1 0.4 2.4 8.0 0.0 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3574) DUF758 PF05527.11 KXL47162.1 - 0.15 12.1 0.0 0.35 10.8 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF758) YlbE PF14003.6 KXL47162.1 - 0.15 12.5 0.9 6.6 7.3 0.0 3.0 3 0 0 3 3 3 0 YlbE-like protein Glyco_hydro_17 PF00332.18 KXL47163.1 - 5.9e-18 65.5 6.1 1.1e-17 64.7 6.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 2-Hacid_dh_C PF02826.19 KXL47164.1 - 3.3e-45 153.6 0.0 4.6e-45 153.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXL47164.1 - 9.1e-07 28.6 0.0 3.8e-06 26.6 0.0 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 KXL47164.1 - 0.0024 18.0 0.0 0.0059 16.7 0.0 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ELFV_dehydrog PF00208.21 KXL47164.1 - 0.014 15.1 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_7 PF13241.6 KXL47164.1 - 0.032 14.6 0.0 0.42 11.1 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding XdhC_C PF13478.6 KXL47164.1 - 0.1 13.1 0.0 0.27 11.8 0.0 1.6 2 0 0 2 2 2 0 XdhC Rossmann domain HET PF06985.11 KXL47165.1 - 3.1e-23 82.7 0.0 4.9e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.18 KXL47166.1 - 3.5e-13 49.2 0.1 5.9e-13 48.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL47166.1 - 4.3e-07 30.0 9.8 8.3e-07 29.0 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Velvet PF11754.8 KXL47167.1 - 0.12 12.3 5.1 0.81 9.6 5.1 2.2 1 1 0 1 1 1 0 Velvet factor Presenilin PF01080.17 KXL47167.1 - 0.43 9.3 1.0 0.46 9.2 1.0 1.1 1 0 0 1 1 1 0 Presenilin WD40 PF00400.32 KXL47169.1 - 1e-13 51.5 1.5 0.035 15.0 0.0 7.7 8 0 0 8 8 8 3 WD domain, G-beta repeat BUD22 PF09073.10 KXL47169.1 - 0.61 9.4 25.3 0.27 10.5 20.7 2.0 2 0 0 2 2 2 0 BUD22 Nop53 PF07767.11 KXL47169.1 - 0.88 8.9 6.1 1.4 8.2 6.1 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 KXL47169.1 - 1.1 7.5 14.3 1.6 7.0 14.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4637 PF15470.6 KXL47169.1 - 1.4 8.7 8.9 0.79 9.4 6.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) Nop14 PF04147.12 KXL47169.1 - 2.3 6.3 18.3 3.3 5.8 18.3 1.2 1 0 0 1 1 1 0 Nop14-like family MS_channel PF00924.18 KXL47170.1 - 8.3e-25 87.5 0.8 1.4e-24 86.8 0.8 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_5 PF13202.6 KXL47170.1 - 0.00026 20.4 0.0 0.00076 18.9 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXL47170.1 - 0.00052 19.7 0.1 0.0038 17.1 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KXL47170.1 - 0.0011 18.3 0.3 0.0027 17.2 0.3 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KXL47170.1 - 0.024 15.1 0.3 0.069 13.6 0.3 1.8 1 0 0 1 1 1 0 EF-hand domain pair PSDC PF12588.8 KXL47171.1 - 2.9e-58 195.8 0.0 4.3e-58 195.3 0.0 1.2 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 KXL47171.1 - 2.9e-37 128.2 0.0 4.8e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.6 KXL47171.1 - 0.01 15.7 0.8 0.084 12.7 0.9 2.2 2 0 0 2 2 2 0 Biotin-lipoyl like Glyco_hydro_3_C PF01915.22 KXL47173.1 - 4.5e-48 163.9 0.0 9e-48 162.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXL47173.1 - 1e-41 143.4 0.0 1.5e-41 142.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXL47173.1 - 7.4e-15 54.8 0.1 1.5e-14 53.8 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain HflK_N PF12221.8 KXL47173.1 - 0.13 12.3 1.1 0.33 11.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial membrane protein N terminal Cgr1 PF03879.14 KXL47174.1 - 8.4e-30 103.3 32.2 9.5e-30 103.2 32.2 1.0 1 0 0 1 1 1 1 Cgr1 family AAA_23 PF13476.6 KXL47174.1 - 1.1 9.7 7.7 1.3 9.5 7.7 1.1 1 0 0 1 1 1 0 AAA domain RR_TM4-6 PF06459.12 KXL47174.1 - 9.1 6.0 13.7 9.7 5.9 13.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mito_carr PF00153.27 KXL47175.1 - 2.1e-63 210.3 0.2 4e-21 74.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXL47175.1 - 0.0007 18.8 0.1 3.2 6.8 0.0 3.4 3 1 0 3 3 3 2 Gammaproteobacterial serine protease DUF3818 PF12825.7 KXL47176.1 - 8.1e-127 422.9 2.6 1.5e-126 422.0 2.6 1.5 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KXL47176.1 - 8.7e-39 132.5 1.6 1.6e-38 131.6 1.6 1.5 1 0 0 1 1 1 1 PX-associated PX PF00787.24 KXL47176.1 - 5e-12 45.8 1.2 6.5e-11 42.2 0.1 3.2 3 1 0 3 3 3 1 PX domain F-box-like_2 PF13013.6 KXL47176.1 - 0.11 12.5 0.1 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 F-box-like domain Alg6_Alg8 PF03155.15 KXL47177.1 - 4.2e-121 405.3 23.9 2.7e-77 260.8 9.4 2.2 2 1 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family COX17 PF05051.13 KXL47178.1 - 9.3e-22 77.1 6.2 1.2e-21 76.8 6.2 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) LRR_6 PF13516.6 KXL47179.1 - 4.8e-12 44.9 5.2 0.01 15.8 0.0 7.3 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 KXL47179.1 - 1.1e-06 28.9 17.8 0.56 10.7 0.2 6.1 6 2 0 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXL47179.1 - 9.5e-06 25.5 0.9 14 6.7 0.0 5.8 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.6 KXL47179.1 - 0.0043 16.8 14.1 1.1 9.0 0.0 5.5 4 2 0 4 4 4 2 Leucine rich repeat DUF604 PF04646.12 KXL47179.1 - 0.11 11.9 0.0 0.3 10.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF604 Pes-10 PF07149.11 KXL47179.1 - 0.56 9.2 17.0 1 8.4 17.0 1.3 1 0 0 1 1 1 0 Pes-10 WBS_methylT PF12589.8 KXL47179.1 - 1.9 9.3 4.2 5 8.0 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome NOA36 PF06524.12 KXL47179.1 - 3.3 6.9 6.2 5.1 6.3 6.2 1.3 1 0 0 1 1 1 0 NOA36 protein MFS_1 PF07690.16 KXL47180.1 - 1.3e-32 113.1 28.8 1.3e-32 113.1 28.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4267 PF14087.6 KXL47180.1 - 8.2 6.5 9.7 1.1 9.3 4.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4267) TPR_2 PF07719.17 KXL47181.1 - 3.5e-21 73.5 5.5 7.8e-06 25.6 0.2 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXL47181.1 - 6.3e-21 73.3 2.3 3.5e-07 29.7 0.1 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXL47181.1 - 3.7e-18 64.9 0.6 8.5e-07 28.6 0.1 4.6 4 0 0 4 4 4 3 TPR repeat TPR_16 PF13432.6 KXL47181.1 - 7e-17 61.8 8.7 5.4e-06 27.0 0.3 4.0 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 KXL47181.1 - 1.1e-15 56.5 0.4 0.00034 20.6 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXL47181.1 - 4e-14 52.1 7.1 0.00031 21.3 0.1 5.6 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 KXL47181.1 - 2.9e-13 49.2 0.7 0.021 15.2 0.0 5.6 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXL47181.1 - 1.3e-12 48.1 5.1 0.0018 18.8 0.1 4.6 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 KXL47181.1 - 2.9e-09 36.3 4.1 0.012 15.6 0.1 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 KXL47181.1 - 1.2e-08 34.9 6.4 0.00061 19.9 0.4 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.6 KXL47181.1 - 1e-07 32.1 4.2 4.4 8.2 0.0 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXL47181.1 - 4e-07 30.2 7.2 4.2e-05 23.8 0.7 4.1 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_20 PF14561.6 KXL47181.1 - 7.6e-07 29.4 2.1 0.27 11.6 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXL47181.1 - 7.4e-05 22.9 2.0 0.0064 16.7 0.3 2.7 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KXL47181.1 - 0.00015 21.1 0.7 0.22 10.7 0.3 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_3 PF07720.12 KXL47181.1 - 0.018 15.0 0.2 1 9.4 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXL47181.1 - 2.1 8.3 8.4 15 5.6 1.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat STT3 PF02516.14 KXL47182.1 - 3.4e-144 481.4 35.1 7.5e-140 467.1 32.1 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit FAD_binding_3 PF01494.19 KXL47183.1 - 2.5e-74 250.6 0.0 3.3e-74 250.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXL47183.1 - 0.0088 15.3 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 KXL47183.1 - 0.038 13.4 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 ThiF family NAD_binding_8 PF13450.6 KXL47183.1 - 0.092 13.0 1.9 0.19 12.0 1.9 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Glyco_hydro_35 PF01301.19 KXL47184.1 - 3.8e-79 266.6 1.0 5.7e-79 266.0 1.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KXL47184.1 - 5.3e-57 191.3 5.6 2.8e-31 108.4 0.1 3.6 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KXL47184.1 - 5.7e-56 189.2 0.0 8.7e-56 188.6 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KXL47184.1 - 4.9e-19 67.7 0.0 2.5e-18 65.4 0.0 2.1 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Peptidase_S28 PF05577.12 KXL47185.1 - 7.7e-47 160.1 4.0 7.7e-46 156.8 4.0 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase S28 HhH-GPD PF00730.25 KXL47186.1 - 2.8e-08 34.2 0.0 5.6e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KXL47186.1 - 0.013 15.4 0.0 0.04 13.8 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif Glyco_hydro_76 PF03663.14 KXL47187.1 - 1.7e-160 534.5 22.2 2e-160 534.3 22.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 UBA PF00627.31 KXL47188.1 - 0.0009 19.1 1.1 0.0025 17.7 0.1 2.3 3 0 0 3 3 3 1 UBA/TS-N domain PLAC8 PF04749.17 KXL47189.1 - 3.2e-22 79.4 13.3 3.8e-22 79.1 13.3 1.1 1 0 0 1 1 1 1 PLAC8 family TRI12 PF06609.13 KXL47190.1 - 2.7e-31 108.6 28.6 3.8e-31 108.2 28.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KXL47190.1 - 6.4e-24 84.5 51.4 6.4e-24 84.5 51.4 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL47190.1 - 2.1e-10 40.1 31.7 6.5e-09 35.2 14.6 2.8 2 0 0 2 2 2 2 Sugar (and other) transporter SRF-TF PF00319.18 KXL47191.1 - 3.5e-21 74.4 0.1 4.9e-21 73.9 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) RIC3 PF15361.6 KXL47191.1 - 0.084 13.3 1.5 0.15 12.5 1.5 1.5 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Shisa PF13908.6 KXL47191.1 - 3.6 7.8 7.5 0.29 11.4 0.5 2.0 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Carb_kinase PF01256.17 KXL47192.1 - 4.1e-58 196.7 0.0 5.3e-58 196.4 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 KXL47192.1 - 0.00037 20.0 0.0 0.00057 19.4 0.0 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.12 KXL47192.1 - 0.0043 16.5 0.1 0.0066 15.9 0.1 1.4 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase Abhydrolase_1 PF00561.20 KXL47194.1 - 2.3e-19 70.0 0.0 1.4e-18 67.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXL47194.1 - 8.9e-13 48.0 0.1 1.3e-12 47.5 0.1 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXL47194.1 - 1.2e-11 45.7 0.0 1.5e-11 45.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 KXL47194.1 - 0.0042 16.5 0.1 0.0064 15.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.20 KXL47194.1 - 0.0078 16.4 0.1 0.013 15.7 0.1 1.4 1 1 0 1 1 1 1 Thioesterase domain Methyltransf_7 PF03492.15 KXL47194.1 - 0.019 14.2 0.0 0.025 13.8 0.0 1.1 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase Abhydrolase_4 PF08386.10 KXL47194.1 - 0.079 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein FSH1 PF03959.13 KXL47194.1 - 0.19 11.3 0.0 1.1 8.9 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase (FSH1) dCMP_cyt_deam_1 PF00383.23 KXL47195.1 - 5.3e-13 48.7 0.8 7.6e-13 48.2 0.8 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 KXL47195.1 - 8.2e-11 42.2 1.0 2.6e-08 34.2 0.1 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 KXL47195.1 - 0.045 13.3 1.6 3 7.4 0.2 2.1 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases HSCB_C PF07743.13 KXL47196.1 - 4.7e-20 71.9 4.0 4.7e-20 71.9 4.0 2.1 2 1 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 KXL47196.1 - 4.5e-07 29.9 1.0 8.1e-07 29.1 0.4 1.8 2 0 0 2 2 2 1 DnaJ domain ThiD2 PF17792.1 KXL47196.1 - 0.00055 20.4 3.2 0.023 15.2 0.6 2.7 1 1 1 3 3 3 1 ThiD2 family SMBP PF16785.5 KXL47196.1 - 0.029 14.6 0.8 0.029 14.6 0.8 1.7 2 0 0 2 2 2 0 Small metal-binding protein Beta-lactamase PF00144.24 KXL47197.1 - 2.6e-32 112.4 0.2 5.7e-32 111.3 0.2 1.4 1 1 0 1 1 1 1 Beta-lactamase PAS PF00989.25 KXL47197.1 - 0.17 11.9 0.0 0.75 9.8 0.0 1.9 1 1 0 2 2 2 0 PAS fold FAD_binding_2 PF00890.24 KXL47198.1 - 7e-124 414.1 2.0 9.1e-124 413.7 2.0 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KXL47198.1 - 2.2e-44 150.6 1.1 3.2e-44 150.0 1.1 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 KXL47198.1 - 0.00026 20.3 0.1 0.12 11.6 0.0 2.3 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.14 KXL47198.1 - 0.00045 19.5 0.2 0.076 12.2 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXL47198.1 - 0.00046 19.4 1.2 0.21 10.6 1.6 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KXL47198.1 - 0.0058 15.9 0.5 0.011 15.0 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KXL47198.1 - 0.14 11.7 1.2 0.32 10.5 1.2 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase EMC3_TMCO1 PF01956.16 KXL47200.1 - 3.8e-53 179.7 1.8 3.8e-53 179.7 1.8 1.9 2 1 0 2 2 2 1 Integral membrane protein EMC3/TMCO1-like DUF1676 PF07898.13 KXL47200.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) SPC25 PF06703.11 KXL47201.1 - 1.8e-46 157.9 0.1 2.1e-46 157.7 0.1 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Nucleotid_trans PF03407.16 KXL47202.1 - 1.4e-18 67.6 0.4 2.2e-18 67.0 0.4 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_hydro_30 PF02055.16 KXL47202.1 - 0.079 11.9 0.1 0.23 10.4 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 30 TIM-barrel domain HTH_Tnp_Tc3_2 PF01498.18 KXL47203.1 - 2.3e-09 37.4 0.4 3e-09 37.0 0.4 1.2 1 0 0 1 1 1 1 Transposase RabGAP-TBC PF00566.18 KXL47204.1 - 6.6e-30 104.4 0.0 1e-29 103.8 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain FtsJ PF01728.19 KXL47205.1 - 9.1e-55 185.5 0.0 1.2e-54 185.1 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 KXL47205.1 - 0.01 15.7 0.3 0.025 14.4 0.3 1.6 1 1 0 1 1 1 0 Methyltransferase domain AJAP1_PANP_C PF15298.6 KXL47205.1 - 0.088 13.0 9.6 0.14 12.3 9.6 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Methyltransf_25 PF13649.6 KXL47205.1 - 0.11 13.2 0.0 0.81 10.4 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 KXL47205.1 - 0.14 11.9 0.0 0.51 10.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Cucumopine_C PF18631.1 KXL47205.1 - 0.19 11.7 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Cucumopine synthase C-terminal helical bundle domain Dicty_REP PF05086.12 KXL47205.1 - 2.2 6.2 3.8 2.8 5.8 3.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF2722 PF10846.8 KXL47206.1 - 1.3e-06 27.7 5.6 1.5e-05 24.2 5.5 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF2722) MIS13 PF08202.11 KXL47207.1 - 0.14 11.4 0.0 0.31 10.3 0.0 1.4 1 1 0 1 1 1 0 Mis12-Mtw1 protein family Fungal_trans PF04082.18 KXL47209.1 - 4.9e-23 81.5 0.0 7.2e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL47209.1 - 1e-07 32.0 15.1 1e-07 32.0 15.1 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HTH_Tnp_Tc3_2 PF01498.18 KXL47211.1 - 4.4e-08 33.3 1.1 5.6e-08 32.9 1.1 1.2 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 KXL47211.1 - 0.043 14.4 0.5 0.066 13.8 0.2 1.4 1 1 0 1 1 1 0 Homeodomain-like domain Glyco_hydro_88 PF07470.13 KXL47212.1 - 0.0017 17.5 0.2 0.042 12.9 0.5 2.1 1 1 1 2 2 2 2 Glycosyl Hydrolase Family 88 Sugar_tr PF00083.24 KXL47213.1 - 2.4e-65 221.2 9.1 2.6e-65 221.0 9.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL47213.1 - 1.1e-15 57.5 32.1 2.7e-11 43.0 11.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily LisH_2 PF16045.5 KXL47213.1 - 0.69 9.0 4.5 0.27 10.3 0.2 2.4 3 0 0 3 3 3 0 LisH Prefoldin PF02996.17 KXL47214.1 - 2e-33 114.9 0.1 4e-33 113.9 0.0 1.5 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.20 KXL47214.1 - 0.0063 16.4 0.4 0.067 13.1 0.0 2.3 2 1 1 3 3 3 1 Prefoldin subunit Filament PF00038.21 KXL47214.1 - 0.011 15.4 0.0 1.9 8.0 0.0 2.1 2 0 0 2 2 2 0 Intermediate filament protein Sec2p PF06428.11 KXL47214.1 - 0.084 12.8 1.3 3.4 7.7 0.7 2.6 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p MetRS-N PF09635.10 KXL47214.1 - 0.11 13.0 0.1 0.45 11.1 0.1 1.9 2 0 0 2 2 2 0 MetRS-N binding domain Acetyltransf_13 PF13880.6 KXL47215.1 - 4.6e-23 81.0 0.0 9.5e-23 80.0 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 KXL47215.1 - 3e-14 52.6 1.7 5.5e-14 51.7 1.7 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.25 KXL47215.1 - 0.01 16.0 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Ureidogly_lyase PF04115.12 KXL47216.1 - 6.5e-64 215.1 0.0 7.8e-64 214.9 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate lyase TPR_19 PF14559.6 KXL47217.1 - 2.4e-11 44.0 11.5 0.0033 17.9 0.0 6.4 5 2 2 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 KXL47217.1 - 7.5e-08 32.6 7.0 0.022 15.5 0.1 6.1 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXL47217.1 - 2.8e-07 31.1 2.5 0.0089 16.7 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXL47217.1 - 2.8e-07 30.1 8.4 3.6 7.6 0.0 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXL47217.1 - 1e-06 28.4 12.2 0.014 15.4 0.1 8.6 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXL47217.1 - 2.9e-05 24.1 0.0 0.13 12.7 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXL47217.1 - 4e-05 23.4 2.8 2.7 8.2 0.0 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_21 PF09976.9 KXL47217.1 - 0.0047 16.7 1.2 0.89 9.2 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 KXL47217.1 - 0.0062 17.1 1.3 8.2 7.3 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXL47217.1 - 0.0089 16.2 8.6 3.2 8.2 0.0 7.5 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_15 PF13429.6 KXL47217.1 - 0.014 14.6 0.6 0.9 8.7 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXL47217.1 - 0.056 13.7 15.7 8.6 6.7 0.2 6.5 5 1 2 7 7 7 0 Tetratricopeptide repeat TPPII_N PF12583.8 KXL47217.1 - 0.19 12.3 0.2 1.2 9.7 0.0 2.2 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal TPR_9 PF13371.6 KXL47217.1 - 0.24 11.6 7.3 3.4 7.9 0.0 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 KXL47217.1 - 1.6 9.1 7.2 2 8.8 0.1 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat Img2 PF05046.14 KXL47218.1 - 1.4e-23 82.9 0.0 1.9e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) eIF3_N PF09440.10 KXL47219.1 - 1.1e-45 155.4 0.7 2.1e-45 154.5 0.7 1.5 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 KXL47219.1 - 3.5e-14 53.2 0.2 9.8e-14 51.7 0.0 1.9 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.9 KXL47219.1 - 0.076 12.7 0.2 0.16 11.7 0.2 1.4 1 0 0 1 1 1 0 26S proteasome subunit RPN7 Kelch_4 PF13418.6 KXL47220.1 - 9.3e-33 112.0 4.3 1.7e-08 34.3 0.0 6.5 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KXL47220.1 - 1.7e-32 111.0 1.4 5.4e-10 39.3 0.0 6.8 7 0 0 7 7 7 3 Galactose oxidase, central domain DUF4110 PF13422.6 KXL47220.1 - 1.5e-28 98.7 1.6 1.5e-28 98.7 1.6 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_5 PF13854.6 KXL47220.1 - 2.8e-20 71.8 4.8 6.7e-08 32.3 0.0 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 KXL47220.1 - 8.7e-20 70.3 4.3 2.1e-05 24.6 0.0 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 KXL47220.1 - 1.8e-16 59.5 0.9 9e-07 28.4 0.0 5.2 5 1 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 KXL47220.1 - 2.5e-14 52.6 5.5 0.00012 21.9 0.0 6.4 6 1 0 6 6 6 3 Kelch motif MCPVI PF02993.14 KXL47220.1 - 0.2 11.5 6.4 0.075 12.8 3.1 1.9 2 0 0 2 2 2 0 Minor capsid protein VI Abhydrolase_1 PF00561.20 KXL47221.1 - 3.6e-12 46.5 0.0 6.1e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXL47221.1 - 5.1e-09 35.8 0.0 1e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KXL47221.1 - 0.00075 19.0 0.0 0.0078 15.7 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KXL47221.1 - 0.012 15.3 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase TraL PF07178.11 KXL47222.1 - 0.02 15.3 2.2 0.02 15.3 2.2 2.3 3 1 0 3 3 3 0 TraL protein HXXEE PF13787.6 KXL47222.1 - 0.36 11.6 5.7 0.084 13.7 1.1 2.1 2 1 0 2 2 2 0 Protein of unknown function with HXXEE motif Exo_endo_phos PF03372.23 KXL47223.1 - 5.6e-19 68.6 0.0 1.1e-18 67.6 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 KXL47223.1 - 1.2e-10 41.4 5.3 1.2e-05 25.5 0.1 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXL47223.1 - 4.2e-10 39.2 5.1 8.8e-07 28.6 4.5 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 KXL47223.1 - 2.2 8.6 5.1 1.1 9.5 0.1 3.1 3 0 0 3 3 3 0 Leucine Rich repeat Frag1 PF10277.9 KXL47224.1 - 2.2e-37 128.7 10.8 2.2e-37 128.7 10.8 2.9 2 1 0 2 2 2 2 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.23 KXL47224.1 - 0.01 15.4 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family RNA_polI_A34 PF08208.11 KXL47225.1 - 1.7e-32 113.2 2.5 1.7e-32 113.2 2.5 5.2 3 2 1 4 4 4 1 DNA-directed RNA polymerase I subunit RPA34.5 CLP1_P PF16575.5 KXL47226.1 - 2e-37 128.9 0.0 3.4e-37 128.1 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MeaB PF03308.16 KXL47226.1 - 0.089 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Gly-rich_Ago1 PF12764.7 KXL47226.1 - 0.2 12.4 0.4 0.58 11.0 0.1 1.9 2 0 0 2 2 2 0 Glycine-rich region of argonaut Glyco_hydro_16 PF00722.21 KXL47227.1 - 0.0064 16.0 0.0 0.017 14.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 SAM_2 PF07647.17 KXL47228.1 - 2e-06 27.8 0.1 3.5e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KXL47228.1 - 0.001 19.4 0.1 0.002 18.5 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4508 PF14969.6 KXL47228.1 - 0.13 12.5 0.1 0.28 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) DUF3074 PF11274.8 KXL47229.1 - 2.7e-43 148.1 0.0 3.6e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Spond_N PF06468.13 KXL47229.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Spondin_N Cnn_1N PF07989.11 KXL47230.1 - 7.3e-22 77.3 10.3 7.3e-22 77.3 10.3 13.9 6 2 9 15 15 15 2 Centrosomin N-terminal motif 1 PACT_coil_coil PF10495.9 KXL47230.1 - 2.1e-18 66.7 0.2 2.1e-18 66.7 0.2 6.0 5 3 0 5 5 5 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Spc7 PF08317.11 KXL47230.1 - 0.005 15.8 12.8 0.005 15.8 12.8 9.6 1 1 8 10 10 10 5 Spc7 kinetochore protein Spc110_C PF18520.1 KXL47230.1 - 0.019 14.6 5.1 0.067 12.8 0.2 3.8 3 0 0 3 3 3 0 Spindle pole body component 110 C-terminal domain bMG3 PF11974.8 KXL47230.1 - 0.058 13.4 4.3 0.63 10.1 0.5 3.0 2 0 0 2 2 2 0 Bacterial alpha-2-macroglobulin MG3 domain DUF4407 PF14362.6 KXL47230.1 - 1.8 7.8 170.1 0.021 14.2 27.5 7.2 1 1 6 7 7 7 0 Domain of unknown function (DUF4407) SGT1 PF07093.11 KXL47231.1 - 3.4e-90 303.2 18.5 1.2e-84 284.9 0.0 2.3 2 1 1 3 3 3 2 SGT1 protein COMPASS-Shg1 PF05205.12 KXL47231.1 - 0.0057 17.4 0.5 0.016 15.9 0.5 1.7 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 WD40 PF00400.32 KXL47232.1 - 1.3e-41 139.8 22.5 3.2e-08 34.1 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 KXL47232.1 - 1.7e-40 138.3 0.2 2.5e-40 137.7 0.2 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 KXL47232.1 - 3.4e-14 52.9 0.2 0.0011 19.2 0.0 5.4 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 KXL47232.1 - 6.5e-07 29.1 0.1 1.4e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 LisH RAB3GAP2_N PF14655.6 KXL47232.1 - 0.0016 17.8 0.1 0.37 10.0 0.0 2.7 2 1 1 3 3 3 2 Rab3 GTPase-activating protein regulatory subunit N-terminus Nucleoporin_N PF08801.11 KXL47232.1 - 0.024 13.4 0.1 2.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Nup133 N terminal like DUF5641 PF18701.1 KXL47232.1 - 0.15 12.3 0.8 1.1 9.4 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5641) Med11 PF10280.9 KXL47233.1 - 5.4e-36 124.1 0.0 6.2e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 Mediator complex protein DUF2397 PF09660.10 KXL47233.1 - 0.065 12.1 0.2 0.089 11.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) Rhomboid PF01694.22 KXL47234.1 - 3.1e-19 69.5 11.4 5.7e-19 68.6 10.7 1.7 2 0 0 2 2 2 1 Rhomboid family HIF-1 PF11413.8 KXL47234.1 - 0.085 12.3 0.3 0.16 11.4 0.3 1.3 1 0 0 1 1 1 0 Hypoxia-inducible factor-1 Chordopox_A13L PF05961.11 KXL47234.1 - 0.47 10.7 1.8 1.1 9.6 0.0 2.3 3 0 0 3 3 3 0 Chordopoxvirus A13L protein DEAD PF00270.29 KXL47235.1 - 1e-42 145.9 0.3 1.9e-42 145.0 0.3 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXL47235.1 - 1.1e-26 93.4 6.0 2.6e-26 92.1 0.3 3.0 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL47235.1 - 4.1e-05 23.6 0.0 4.1e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit EPL1 PF10513.9 KXL47235.1 - 0.025 15.0 1.1 0.17 12.2 1.8 1.9 2 0 0 2 2 2 0 Enhancer of polycomb-like CMS1 PF14617.6 KXL47235.1 - 0.1 12.0 0.0 0.1 12.0 0.0 2.4 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DUF2722 PF10846.8 KXL47235.1 - 0.72 8.7 13.0 1 8.2 13.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 KXL47235.1 - 1.8 8.5 16.8 2.6 8.0 16.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GRP PF07172.11 KXL47235.1 - 4.4 8.1 14.3 8.3 7.2 14.3 1.4 1 0 0 1 1 1 0 Glycine rich protein family UPF0560 PF10577.9 KXL47235.1 - 5.5 5.4 8.4 7.9 4.8 8.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 HUN PF08729.10 KXL47236.1 - 5.5e-09 35.9 0.0 1.1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Med3 PF11593.8 KXL47236.1 - 0.0024 17.1 2.6 0.0031 16.8 1.8 1.6 1 1 0 1 1 1 1 Mediator complex subunit 3 fungal DUF1764 PF08576.10 KXL47236.1 - 0.16 12.9 1.7 0.26 12.2 0.2 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Thaumatin PF00314.17 KXL47237.1 - 1.8e-70 236.9 8.3 2.7e-70 236.3 8.3 1.3 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 KXL47237.1 - 0.00013 21.4 4.6 0.0082 15.5 0.0 2.4 2 1 0 2 2 2 2 Beta-1,3-glucanase NAD_binding_11 PF14833.6 KXL47238.1 - 3.2e-29 101.6 0.3 5.7e-28 97.6 0.1 2.2 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 KXL47238.1 - 2.3e-25 89.6 0.1 3.6e-25 89.0 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KXL47238.1 - 0.00015 21.2 0.0 0.0003 20.2 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KXL47238.1 - 0.0051 16.4 0.0 0.032 13.8 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain XdhC_C PF13478.6 KXL47238.1 - 0.0064 17.0 0.1 0.058 13.9 0.0 2.1 2 0 0 2 2 2 1 XdhC Rossmann domain F420_oxidored PF03807.17 KXL47238.1 - 0.032 14.8 0.1 0.088 13.4 0.1 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 KXL47238.1 - 0.072 12.4 0.1 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PDH PF02153.17 KXL47238.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase 3HCDH_N PF02737.18 KXL47238.1 - 0.12 12.2 0.0 0.43 10.4 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cyt-b5 PF00173.28 KXL47239.1 - 6.3e-11 42.3 0.0 9.6e-11 41.7 0.0 1.5 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4202 PF13875.6 KXL47241.1 - 5.2e-17 62.4 0.0 2e-16 60.4 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4202) MFS_1 PF07690.16 KXL47242.1 - 2.2e-30 105.8 54.2 6.9e-30 104.2 36.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXL47242.1 - 0.00021 19.9 5.8 0.00021 19.9 5.8 2.6 3 0 0 3 3 3 2 Fungal trichothecene efflux pump (TRI12) adh_short_C2 PF13561.6 KXL47243.1 - 7.1e-47 159.9 0.5 8.8e-47 159.6 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL47243.1 - 3e-45 154.1 0.3 4.2e-45 153.6 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL47243.1 - 1.6e-12 47.7 0.7 2.8e-12 46.9 0.7 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL47243.1 - 0.0021 17.5 0.1 0.013 14.9 0.1 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family malic PF00390.19 KXL47243.1 - 0.043 13.6 0.0 2.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Malic enzyme, N-terminal domain GDP_Man_Dehyd PF16363.5 KXL47243.1 - 0.23 10.8 0.0 0.77 9.1 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Glyco_hydro_7 PF00840.20 KXL47244.1 - 8.2e-124 413.6 12.6 9.2e-124 413.5 12.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Cu-oxidase_2 PF07731.14 KXL47245.1 - 3.3e-10 39.8 3.3 8.5e-08 32.0 3.4 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXL47245.1 - 8.5e-06 25.8 3.2 0.0066 16.4 0.0 3.4 3 0 0 3 3 3 2 Multicopper oxidase ZF-HD_dimer PF04770.12 KXL47249.1 - 0.24 11.7 1.2 0.72 10.2 0.1 2.1 2 0 0 2 2 2 0 ZF-HD protein dimerisation region Solute_trans_a PF03619.16 KXL47250.1 - 1e-94 317.0 9.8 1.3e-94 316.7 9.8 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha GTP_EFTU PF00009.27 KXL47251.1 - 1.6e-64 217.1 0.2 2.2e-64 216.6 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KXL47251.1 - 4.3e-34 116.9 0.0 1.4e-33 115.3 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KXL47251.1 - 2.4e-21 75.6 0.0 5.9e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KXL47251.1 - 1.1e-11 44.6 0.0 2.9e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KXL47251.1 - 1.3e-11 44.7 0.0 5.1e-11 42.8 0.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXL47251.1 - 0.0012 18.9 0.2 0.0027 17.8 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PWI PF01480.17 KXL47253.1 - 1.9e-09 37.7 0.0 3.9e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 KXL47253.1 - 0.00011 21.9 0.2 0.00037 20.3 0.2 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXL47253.1 - 0.00023 21.1 0.1 0.00048 20.1 0.1 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KXL47253.1 - 0.0013 18.5 0.0 0.0055 16.5 0.0 2.0 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_3 PF08777.11 KXL47253.1 - 0.016 15.3 9.4 3.1 7.9 0.0 3.2 3 0 0 3 3 3 0 RNA binding motif DUF4407 PF14362.6 KXL47253.1 - 0.064 12.6 6.1 0.11 11.8 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PHM7_cyt PF14703.6 KXL47253.1 - 0.12 12.5 4.4 4.1 7.6 0.0 2.5 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Atg14 PF10186.9 KXL47253.1 - 0.28 10.2 6.6 0.46 9.5 6.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf_CCCH_4 PF18345.1 KXL47253.1 - 0.3 11.2 0.7 0.54 10.4 0.7 1.4 1 0 0 1 1 1 0 Zinc finger domain TMPIT PF07851.13 KXL47253.1 - 1.7 7.8 9.9 2.5 7.3 9.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein Vfa1 PF08432.10 KXL47253.1 - 2.6 8.4 12.2 5 7.4 12.2 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 zf-CpG_bind_C PF12269.8 KXL47253.1 - 4 7.2 12.7 6.6 6.4 12.7 1.2 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain Borrelia_P83 PF05262.11 KXL47253.1 - 4.7 5.6 13.5 7.3 5.0 13.5 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein FapA PF03961.13 KXL47253.1 - 8.8 4.8 14.3 13 4.2 14.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Cyclin_N PF00134.23 KXL47255.1 - 5.6e-06 26.1 0.0 2.9e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Chitin_synth_2 PF03142.15 KXL47256.1 - 1.2e-240 799.6 0.7 1.7e-240 799.2 0.7 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 KXL47256.1 - 5.2e-71 239.8 0.0 3.2e-70 237.2 0.0 2.0 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 KXL47256.1 - 9.8e-16 57.4 0.1 1.5e-14 53.7 0.3 2.5 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 KXL47256.1 - 2.1e-14 53.4 0.4 6.3e-11 42.3 0.0 3.0 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 KXL47256.1 - 7.2e-11 42.4 3.4 7.2e-11 42.4 3.4 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXL47256.1 - 8.9e-10 38.8 0.0 6.8e-09 36.0 0.1 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KXL47256.1 - 0.004 17.0 0.0 1.5 8.6 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KXL47256.1 - 0.11 12.0 0.1 0.32 10.5 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 KXL47257.1 - 8.6e-227 753.9 0.2 1.2e-226 753.5 0.2 1.2 1 0 0 1 1 1 1 Chitin synthase DEK_C PF08766.11 KXL47257.1 - 6.5e-16 58.0 0.1 4.2e-15 55.4 0.3 2.1 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 KXL47257.1 - 3.9e-15 55.8 0.8 6.6e-09 35.8 0.0 3.8 3 1 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 KXL47257.1 - 6.1e-12 45.9 2.1 6.1e-12 45.9 2.1 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXL47257.1 - 1.1e-11 45.0 0.0 3.1e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Myosin_head PF00063.21 KXL47257.1 - 4.6e-11 41.7 0.0 3.8e-09 35.4 0.0 2.2 1 1 0 2 2 2 2 Myosin head (motor domain) Glyco_transf_21 PF13506.6 KXL47257.1 - 0.0012 18.4 0.0 0.0049 16.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 21 DUF5360 PF17314.2 KXL47257.1 - 0.0089 16.1 3.0 0.029 14.4 3.0 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5360) Glycos_transf_2 PF00535.26 KXL47257.1 - 0.011 15.5 0.0 0.35 10.7 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 ADH_zinc_N PF00107.26 KXL47258.1 - 1.4e-21 76.8 0.8 2.1e-21 76.2 0.4 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXL47258.1 - 4.4e-12 47.2 0.0 9.9e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXL47258.1 - 5.8e-06 25.9 0.0 8.8e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N PF08240.12 KXL47258.1 - 0.00022 21.1 0.0 0.00043 20.1 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KXL47258.1 - 0.019 14.4 0.2 0.037 13.5 0.2 1.5 1 0 0 1 1 1 0 short chain dehydrogenase ACP_syn_III_C PF08541.10 KXL47258.1 - 0.13 12.5 0.3 0.26 11.5 0.3 1.5 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal IBR PF01485.21 KXL47259.1 - 0.061 13.6 2.1 0.061 13.6 2.1 3.0 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_6 PF14835.6 KXL47259.1 - 0.33 10.9 8.3 0.19 11.7 0.8 2.8 2 1 0 2 2 2 0 zf-RING of BARD1-type protein DZR PF12773.7 KXL47259.1 - 0.66 10.1 21.1 0.29 11.2 4.0 3.2 3 1 0 3 3 3 0 Double zinc ribbon zinc_ribbon_5 PF13719.6 KXL47259.1 - 2.8 7.8 11.1 29 4.5 0.1 3.1 2 1 0 2 2 2 0 zinc-ribbon domain PNP_UDP_1 PF01048.20 KXL47260.1 - 0.056 12.7 0.0 0.056 12.7 0.0 1.1 1 0 0 1 1 1 0 Phosphorylase superfamily ABC_tran PF00005.27 KXL47261.1 - 6.4e-47 159.5 0.1 9.7e-24 84.4 0.0 3.6 2 1 0 2 2 2 2 ABC transporter 4HB PF17947.1 KXL47261.1 - 5.3e-29 100.1 0.1 1.2e-27 95.7 0.0 2.9 2 0 0 2 2 2 1 Four helical bundle domain SMC_N PF02463.19 KXL47261.1 - 7.1e-17 61.6 0.0 3.6e-06 26.6 0.0 3.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KXL47261.1 - 3e-16 60.1 0.0 0.0021 17.9 0.0 4.9 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KXL47261.1 - 2.8e-09 37.8 7.9 0.00016 22.3 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.6 KXL47261.1 - 3.9e-08 32.9 0.2 0.013 15.2 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 KXL47261.1 - 7.9e-08 32.7 0.1 0.01 16.1 0.1 2.7 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KXL47261.1 - 7.9e-07 29.1 0.1 0.0014 18.6 0.0 2.9 3 0 0 3 3 2 1 RsgA GTPase PduV-EutP PF10662.9 KXL47261.1 - 3e-06 27.1 0.1 0.14 11.9 0.0 3.0 3 0 0 3 3 2 2 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 KXL47261.1 - 3.1e-06 27.6 0.1 0.1 13.0 0.0 4.4 5 0 0 5 5 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXL47261.1 - 3.9e-06 27.2 0.1 0.19 12.0 0.0 4.1 5 0 0 5 5 3 2 AAA domain AAA_18 PF13238.6 KXL47261.1 - 4e-06 27.4 0.1 0.098 13.2 0.0 3.2 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KXL47261.1 - 6.4e-06 26.2 0.0 0.0061 16.6 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KXL47261.1 - 2e-05 25.0 0.8 0.25 11.7 0.0 3.7 3 2 0 3 3 2 2 AAA ATPase domain HEAT_2 PF13646.6 KXL47261.1 - 6.7e-05 23.2 0.3 0.075 13.4 0.1 3.1 1 1 2 3 3 3 2 HEAT repeats G-alpha PF00503.20 KXL47261.1 - 0.00012 21.3 0.1 0.55 9.3 0.0 2.8 3 0 0 3 3 3 2 G-protein alpha subunit Dynamin_N PF00350.23 KXL47261.1 - 0.00014 22.0 0.3 0.0029 17.7 0.0 3.0 3 0 0 3 3 2 1 Dynamin family HEAT PF02985.22 KXL47261.1 - 0.00015 21.7 1.7 0.41 11.0 0.1 4.6 4 0 0 4 4 3 1 HEAT repeat MeaB PF03308.16 KXL47261.1 - 0.00018 20.6 0.1 0.11 11.4 0.0 2.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 KXL47261.1 - 0.0002 21.2 0.0 0.82 9.4 0.0 3.0 3 0 0 3 3 3 2 AAA domain DRIM PF07539.12 KXL47261.1 - 0.00021 19.7 0.8 0.022 13.1 0.1 2.2 1 1 1 2 2 2 1 Down-regulated in metastasis RNA_helicase PF00910.22 KXL47261.1 - 0.00038 20.8 0.1 0.83 10.1 0.0 3.1 3 0 0 3 3 2 1 RNA helicase AAA_14 PF13173.6 KXL47261.1 - 0.00038 20.5 0.1 1 9.4 0.0 3.4 3 0 0 3 3 2 1 AAA domain AAA_15 PF13175.6 KXL47261.1 - 0.0004 20.2 4.0 0.62 9.7 0.0 3.9 2 2 1 3 3 3 1 AAA ATPase domain cobW PF02492.19 KXL47261.1 - 0.00042 20.0 0.1 0.25 10.9 0.0 3.1 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KXL47261.1 - 0.00057 19.8 0.0 0.35 10.8 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 KXL47261.1 - 0.00068 19.8 0.0 1.2 9.3 0.0 3.3 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.17 KXL47261.1 - 0.00073 19.7 3.1 0.23 11.5 0.0 4.1 4 0 0 4 4 4 1 Helicase HerA, central domain DUF3385 PF11865.8 KXL47261.1 - 0.00086 19.3 0.5 0.16 11.8 0.1 3.2 2 1 1 3 3 3 1 Domain of unknown function (DUF3385) AAA_27 PF13514.6 KXL47261.1 - 0.0013 18.4 0.1 0.8 9.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXL47261.1 - 0.0015 18.3 0.0 1.2 8.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain Roc PF08477.13 KXL47261.1 - 0.0021 18.3 0.1 2.4 8.4 0.0 3.0 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 KXL47261.1 - 0.0038 16.4 0.1 0.22 10.7 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain ATPase_2 PF01637.18 KXL47261.1 - 0.0043 17.0 0.1 1.4 8.8 0.0 3.5 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea TsaE PF02367.17 KXL47261.1 - 0.0045 17.0 1.7 7.1 6.6 0.1 3.6 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP_bind_1 PF03029.17 KXL47261.1 - 0.0049 16.7 0.0 4 7.1 0.0 2.8 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein ATP-synt_ab PF00006.25 KXL47261.1 - 0.0085 15.8 0.0 3.2 7.4 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.6 KXL47261.1 - 0.013 15.7 0.0 1.4 9.2 0.0 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit IstB_IS21 PF01695.17 KXL47261.1 - 0.014 15.1 0.0 5 6.8 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Septin PF00735.18 KXL47261.1 - 0.019 14.2 0.0 4.6 6.4 0.0 2.6 2 0 0 2 2 2 0 Septin MMS19_N PF14500.6 KXL47261.1 - 0.023 14.3 0.2 6.8 6.2 0.2 3.0 2 1 1 3 3 2 0 Dos2-interacting transcription regulator of RNA-Pol-II MobB PF03205.14 KXL47261.1 - 0.034 14.0 0.0 11 5.9 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.21 KXL47261.1 - 0.035 13.5 0.0 5.1 6.4 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI CLP1_P PF16575.5 KXL47261.1 - 0.046 13.5 0.1 4.2 7.1 0.0 3.1 3 0 0 3 3 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop T2SSE PF00437.20 KXL47261.1 - 0.048 12.7 0.2 7.4 5.5 0.0 2.7 3 0 0 3 3 2 0 Type II/IV secretion system protein Vac14_Fab1_bd PF12755.7 KXL47261.1 - 0.055 14.1 0.1 0.66 10.6 0.0 2.8 2 1 1 3 3 2 0 Vacuolar 14 Fab1-binding region UME PF08064.13 KXL47261.1 - 0.057 13.3 0.5 12 5.9 0.1 3.2 3 0 0 3 3 3 0 UME (NUC010) domain AAA_7 PF12775.7 KXL47261.1 - 0.059 12.9 0.0 7.8 6.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region HEAT_EZ PF13513.6 KXL47261.1 - 0.06 13.9 4.3 1.2 9.8 0.0 4.8 6 0 0 6 6 3 0 HEAT-like repeat Rad17 PF03215.15 KXL47261.1 - 0.065 13.2 0.0 3.6 7.5 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_5 PF07728.14 KXL47261.1 - 0.083 12.9 0.0 17 5.4 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Arf PF00025.21 KXL47261.1 - 0.094 12.2 0.0 15 5.0 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family NTPase_1 PF03266.15 KXL47261.1 - 0.095 12.6 0.1 17 5.3 0.1 2.7 2 0 0 2 2 2 0 NTPase PRK PF00485.18 KXL47261.1 - 0.11 12.2 0.0 5 6.8 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MukB PF04310.12 KXL47261.1 - 0.14 12.0 0.0 22 4.8 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal RuvB_N PF05496.12 KXL47261.1 - 0.16 11.7 0.1 14 5.4 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain MMS19_C PF12460.8 KXL47261.1 - 0.85 8.7 3.4 25 3.8 1.1 3.0 2 1 0 2 2 2 0 RNAPII transcription regulator C-terminal AAA_13 PF13166.6 KXL47261.1 - 4.3 5.9 18.2 0.46 9.1 0.0 5.1 5 1 1 6 6 6 0 AAA domain HAD_2 PF13419.6 KXL47262.1 - 2.2e-11 44.2 0.0 2.9e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXL47262.1 - 2.5e-11 44.3 0.0 5.1e-10 40.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXL47262.1 - 0.00028 20.9 0.0 0.00043 20.3 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like RibD_C PF01872.17 KXL47263.1 - 5.7e-34 117.7 0.0 6.7e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain Glyco_hydro_1 PF00232.18 KXL47265.1 - 1.8e-98 329.9 0.9 2.3e-98 329.6 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_31 PF01055.26 KXL47267.1 - 6e-64 216.8 0.7 1.2e-36 126.9 0.0 3.2 2 1 1 3 3 3 3 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KXL47267.1 - 1.7e-14 54.0 0.0 3.6e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Pyr_redox_2 PF07992.14 KXL47268.1 - 7.4e-16 58.2 0.0 2.4e-13 50.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXL47268.1 - 2.3e-12 46.1 1.4 3.1e-12 45.7 0.0 1.8 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXL47268.1 - 6.5e-12 45.5 0.0 5.8e-09 36.1 0.0 3.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXL47268.1 - 2.7e-11 43.3 0.0 7.7e-11 41.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXL47268.1 - 5.4e-08 32.4 0.0 4.5e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 KXL47268.1 - 7.5e-05 22.0 0.0 0.00023 20.4 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KXL47268.1 - 0.00011 21.5 0.0 0.0016 17.7 0.0 2.1 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KXL47268.1 - 0.0012 18.5 0.5 0.031 13.9 0.0 2.7 3 1 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXL47268.1 - 0.0042 15.9 0.9 0.28 9.8 0.0 2.5 3 0 0 3 3 3 1 HI0933-like protein Shikimate_DH PF01488.20 KXL47268.1 - 0.0073 16.4 0.0 0.19 11.8 0.0 2.7 4 0 0 4 4 4 1 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.7 KXL47268.1 - 0.044 13.1 0.0 0.083 12.2 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXL47268.1 - 0.062 13.9 0.2 1.6 9.4 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXL47268.1 - 0.095 11.8 1.1 0.31 10.1 0.0 2.2 2 1 1 3 3 3 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KXL47268.1 - 0.13 11.3 0.0 5.2 6.0 0.0 2.9 2 1 0 2 2 2 0 Lycopene cyclase protein V-SNARE_C PF12352.8 KXL47269.1 - 7.4e-16 58.2 0.2 1.6e-15 57.1 0.2 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KXL47269.1 - 2.6e-05 24.0 0.1 9.8e-05 22.2 0.0 1.9 2 1 0 2 2 2 1 Sec20 Snapin_Pallidin PF14712.6 KXL47269.1 - 0.0027 18.1 0.2 0.025 15.0 0.1 2.1 2 0 0 2 2 2 1 Snapin/Pallidin Sigma70_r4 PF04545.16 KXL47269.1 - 0.037 13.6 0.1 0.083 12.4 0.1 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 Spc7 PF08317.11 KXL47269.1 - 0.32 9.8 3.4 0.3 9.9 2.2 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein ASXH PF13919.6 KXL47269.1 - 0.49 10.4 3.4 3.9 7.5 0.0 2.7 2 1 0 2 2 2 0 Asx homology domain SRP68 PF16969.5 KXL47270.1 - 1.9e-169 565.3 7.2 2.8e-169 564.7 7.2 1.2 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 AA_permease PF00324.21 KXL47271.1 - 1.7e-141 472.1 33.1 2e-141 471.9 33.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXL47271.1 - 2.8e-35 122.0 36.7 3.7e-35 121.6 36.7 1.1 1 0 0 1 1 1 1 Amino acid permease Sugar_tr PF00083.24 KXL47272.1 - 3.8e-39 134.8 24.3 6e-38 130.9 24.3 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL47272.1 - 8.9e-33 113.7 49.8 2.6e-30 105.6 28.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily AAA PF00004.29 KXL47273.1 - 1.2e-16 61.4 0.0 1.3e-15 58.0 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXL47273.1 - 0.002 18.2 0.0 0.0075 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXL47273.1 - 0.0047 17.2 1.9 0.1 12.9 0.5 2.9 1 1 1 2 2 2 1 AAA domain AAA_11 PF13086.6 KXL47273.1 - 0.079 12.7 0.0 0.079 12.7 0.0 4.7 2 1 1 3 3 3 0 AAA domain PYRIN PF02758.16 KXL47273.1 - 0.22 11.7 1.9 0.58 10.3 1.9 1.7 1 0 0 1 1 1 0 PAAD/DAPIN/Pyrin domain AAA_16 PF13191.6 KXL47273.1 - 3.4 8.0 8.6 6.2 7.2 4.0 3.1 2 1 0 2 2 2 0 AAA ATPase domain Muted PF14942.6 KXL47274.1 - 0.2 12.0 0.1 0.2 12.0 0.1 2.8 3 1 1 4 4 4 0 Organelle biogenesis, Muted-like protein HET PF06985.11 KXL47275.1 - 3.3e-11 43.7 1.3 1e-10 42.1 1.3 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Coatomer_WDAD PF04053.14 KXL47277.1 - 6e-147 490.3 0.0 9.9e-147 489.6 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 KXL47277.1 - 2.8e-90 303.0 0.0 3.9e-90 302.5 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 KXL47277.1 - 7.6e-23 80.4 6.0 9.1e-08 32.7 0.6 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL47277.1 - 0.00011 22.4 2.4 0.0051 17.1 0.1 3.8 3 2 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXL47277.1 - 0.00063 18.5 0.3 0.22 10.1 0.2 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Sugar_tr PF00083.24 KXL47279.1 - 1e-77 262.0 26.5 1.2e-77 261.7 26.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL47279.1 - 6.1e-12 45.1 37.1 6.1e-12 45.1 37.1 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXL47279.1 - 4.5 6.0 25.3 0.057 12.3 11.0 2.3 2 1 0 2 2 2 0 MFS_1 like family Dynamin_N PF00350.23 KXL47280.1 - 3.3e-32 111.9 0.1 8.1e-32 110.6 0.0 1.7 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 KXL47280.1 - 2.7e-21 76.1 0.0 3.6e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Dynamin central region AAA_16 PF13191.6 KXL47280.1 - 0.00071 20.0 0.1 0.0041 17.5 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 KXL47280.1 - 0.0028 17.7 0.1 0.019 15.1 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KXL47280.1 - 0.066 12.5 0.1 5.3 6.3 0.0 2.4 2 0 0 2 2 2 0 AIG1 family Peptidase_M75 PF09375.10 KXL47280.1 - 0.1 12.1 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Imelysin DSBA PF01323.20 KXL47281.1 - 0.11 12.3 0.4 0.12 12.1 0.4 1.1 1 0 0 1 1 1 0 DSBA-like thioredoxin domain DUF1776 PF08643.10 KXL47282.1 - 1.4e-62 211.7 0.1 1e-58 199.1 0.1 2.1 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short PF00106.25 KXL47282.1 - 9.7e-06 25.2 0.0 3.1e-05 23.5 0.0 1.9 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL47282.1 - 1e-05 25.2 0.0 2.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RskA PF10099.9 KXL47282.1 - 0.0073 16.6 0.8 0.015 15.6 0.8 1.4 1 0 0 1 1 1 1 Anti-sigma-K factor rskA HTH_psq PF05225.16 KXL47286.1 - 0.00098 18.8 0.3 0.0015 18.3 0.3 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.6 KXL47286.1 - 0.01 15.6 0.1 0.014 15.2 0.1 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_7 PF02796.15 KXL47286.1 - 0.026 14.6 0.3 0.044 13.9 0.3 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_Tnp_ISL3 PF13542.6 KXL47286.1 - 0.028 13.9 0.1 0.037 13.4 0.1 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_1 PF00126.27 KXL47286.1 - 0.043 13.8 0.2 0.056 13.4 0.2 1.3 1 1 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family SpoIIID PF12116.8 KXL47286.1 - 0.048 13.8 0.1 0.052 13.7 0.1 1.2 1 0 0 1 1 1 0 Stage III sporulation protein D adh_short_C2 PF13561.6 KXL47287.1 - 8.7e-49 166.2 1.2 2.8e-25 89.3 0.1 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL47287.1 - 5.9e-29 100.9 0.1 8.4e-23 80.8 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 KXL47287.1 - 4e-06 26.9 0.1 2e-05 24.6 0.1 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL47287.1 - 0.14 11.6 0.1 0.26 10.7 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fungal_trans_2 PF11951.8 KXL47288.1 - 9.5e-49 166.2 0.0 1.3e-48 165.8 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1849 PF08904.11 KXL47289.1 - 0.034 13.7 0.2 0.042 13.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1849) DUF3918 PF13056.6 KXL47289.1 - 0.42 10.3 2.1 0.51 10.0 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) Ferric_reduct PF01794.19 KXL47290.1 - 4.7e-17 62.3 7.6 1.8e-16 60.4 7.6 2.1 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXL47290.1 - 5.3e-17 62.4 0.1 1.9e-14 54.1 0.1 2.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXL47290.1 - 1.8e-10 40.9 0.0 3.8e-06 27.0 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.21 KXL47290.1 - 0.081 13.6 0.0 0.55 10.9 0.0 2.4 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain Peptidase_U4 PF03419.13 KXL47290.1 - 0.99 8.6 6.3 0.19 11.0 1.9 1.8 2 0 0 2 2 2 0 Sporulation factor SpoIIGA AMP-binding PF00501.28 KXL47292.1 - 1.3e-58 198.7 0.1 1.3e-23 83.3 0.0 4.5 3 1 0 3 3 3 3 AMP-binding enzyme DMAP_binding PF06464.11 KXL47292.1 - 3e-10 40.9 0.1 9e-10 39.4 0.1 1.8 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.12 KXL47292.1 - 0.0042 17.1 0.4 0.0087 16.0 0.4 1.5 1 0 0 1 1 1 1 Gas vesicle protein G Lipase_chap PF03280.14 KXL47292.1 - 0.2 11.6 0.4 0.37 10.7 0.4 1.3 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein Acetyltransf_1 PF00583.25 KXL47294.1 - 0.08 13.2 0.0 0.096 12.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family APC_u15 PF16636.5 KXL47295.1 - 0.072 13.5 1.9 0.2 12.1 1.9 1.7 1 0 0 1 1 1 0 Unstructured region on APC between APC_crr regions 5 and 6 Zn_clus PF00172.18 KXL47295.1 - 3.4 7.9 15.7 0.09 12.9 9.2 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain AIM24 PF01987.17 KXL47297.1 - 7.8e-48 162.9 0.1 9.4e-48 162.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Aldo_ket_red PF00248.21 KXL47298.1 - 4.5e-69 232.9 0.0 5.7e-69 232.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GCIP PF13324.6 KXL47298.1 - 0.056 13.0 0.0 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting Vps39_2 PF10367.9 KXL47299.1 - 2.5e-08 34.3 0.0 6.5e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 KXL47299.1 - 0.0015 18.8 0.1 0.25 11.6 0.0 3.0 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 TPR_12 PF13424.6 KXL47299.1 - 0.1 12.9 0.6 20 5.6 0.0 3.9 3 2 2 5 5 5 0 Tetratricopeptide repeat DUF3455 PF11937.8 KXL47300.1 - 6.9e-40 137.0 0.1 8.9e-40 136.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 KXL47300.1 - 0.18 12.0 1.8 0.92 9.7 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2990) NAD_binding_10 PF13460.6 KXL47302.1 - 3.8e-40 137.8 0.3 4.8e-40 137.4 0.3 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXL47302.1 - 1.9e-09 37.3 0.0 2.6e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KXL47302.1 - 5.3e-09 36.0 0.3 3.9e-08 33.1 0.1 2.3 2 2 1 3 3 3 1 NmrA-like family NAD_binding_4 PF07993.12 KXL47302.1 - 3.2e-05 23.2 0.0 0.00027 20.2 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 KXL47302.1 - 0.0018 17.3 0.0 0.0023 17.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 KXL47302.1 - 0.025 15.2 0.2 0.077 13.6 0.1 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.17 KXL47302.1 - 0.042 12.9 0.0 0.064 12.4 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Glyco_trans_4_4 PF13579.6 KXL47302.1 - 0.066 13.7 0.1 0.21 12.0 0.0 1.8 1 1 0 2 2 2 0 Glycosyl transferase 4-like domain Ligase_CoA PF00549.19 KXL47302.1 - 0.099 12.5 0.4 0.28 11.0 0.1 1.8 2 0 0 2 2 2 0 CoA-ligase GDP_Man_Dehyd PF16363.5 KXL47302.1 - 0.11 11.8 0.0 0.28 10.5 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase SDP_N PF12278.8 KXL47303.1 - 2.4 8.3 7.3 0.5 10.5 2.0 2.7 2 0 0 2 2 2 0 Sex determination protein N terminal Amidase PF01425.21 KXL47304.1 - 2.4e-70 237.8 0.0 1.3e-69 235.4 0.0 1.9 1 1 0 1 1 1 1 Amidase Polysacc_deac_1 PF01522.21 KXL47305.1 - 8e-06 25.8 0.0 1.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Oxidored_molyb PF00174.19 KXL47306.1 - 1.6e-50 171.1 0.0 2.8e-50 170.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KXL47306.1 - 6.6e-32 110.4 0.8 1.3e-31 109.5 0.8 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 KXL47306.1 - 2e-10 40.7 0.0 4.6e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2381 PF09544.10 KXL47306.1 - 0.11 12.0 0.1 0.18 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) BNR PF02012.20 KXL47306.1 - 0.19 11.8 1.6 0.51 10.5 0.2 2.6 2 0 0 2 2 2 0 BNR/Asp-box repeat Keratin_2_head PF16208.5 KXL47307.1 - 0.047 13.8 6.4 0.078 13.1 6.4 1.4 1 0 0 1 1 1 0 Keratin type II head SAD_SRA PF02182.17 KXL47308.1 - 8.6e-10 38.5 0.0 6.9e-09 35.6 0.0 2.1 1 1 0 1 1 1 1 SAD/SRA domain Iso_dh PF00180.20 KXL47309.1 - 4.3e-128 427.3 0.0 4.9e-128 427.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SET PF00856.28 KXL47310.1 - 0.0076 16.7 0.0 0.0093 16.4 0.0 1.3 1 0 0 1 1 1 1 SET domain EST1_DNA_bind PF10373.9 KXL47312.1 - 4.5e-45 154.3 0.2 6.9e-45 153.7 0.2 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 KXL47312.1 - 2.5e-16 60.5 0.8 1.6e-15 58.0 0.1 2.5 2 1 0 2 2 2 1 Telomerase activating protein Est1 Ephrin_lbd PF01404.19 KXL47312.1 - 0.0029 17.7 0.0 0.0063 16.6 0.0 1.5 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain zf-C2H2_jaz PF12171.8 KXL47313.1 - 0.0039 17.4 0.9 0.13 12.6 0.2 2.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding FRG2 PF15315.6 KXL47313.1 - 0.0051 17.0 2.2 0.88 9.7 2.4 2.2 2 0 0 2 2 2 2 Facioscapulohumeral muscular dystrophy candidate 2 zf-C2H2 PF00096.26 KXL47313.1 - 0.07 13.6 12.3 0.54 10.8 0.5 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type Amino_oxidase PF01593.24 KXL47315.1 - 5.7e-48 164.3 0.0 6.6e-48 164.1 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXL47315.1 - 1.2e-11 44.6 0.2 2.5e-11 43.6 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXL47315.1 - 3.8e-09 36.1 2.8 5.9e-09 35.5 2.8 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KXL47315.1 - 7e-09 35.5 0.0 9.7e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXL47315.1 - 1.6e-07 30.4 0.2 2.5e-07 29.7 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KXL47315.1 - 7.9e-07 28.6 0.8 1.2e-06 28.0 0.8 1.2 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KXL47315.1 - 1.1e-06 28.5 1.0 0.00011 22.0 1.7 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXL47315.1 - 1.6e-05 24.3 0.1 3.1e-05 23.4 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXL47315.1 - 0.00013 21.2 1.2 0.00022 20.4 1.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KXL47315.1 - 0.00053 19.3 0.3 0.0037 16.6 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXL47315.1 - 0.0008 19.9 0.4 0.0018 18.8 0.4 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXL47315.1 - 0.0017 17.5 0.7 0.0033 16.6 0.6 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 KXL47315.1 - 0.0023 17.2 1.9 0.0053 16.0 1.5 1.7 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 KXL47315.1 - 0.01 15.1 0.3 0.018 14.4 0.3 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FMO-like PF00743.19 KXL47315.1 - 0.026 13.0 0.0 0.037 12.4 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like 3HCDH_N PF02737.18 KXL47315.1 - 0.062 13.2 0.5 0.12 12.2 0.5 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KXL47315.1 - 0.064 13.2 0.1 1.3 9.0 0.2 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding BrkDBD PF09607.10 KXL47316.1 - 0.073 12.9 0.7 0.1 12.4 0.5 1.5 1 1 0 1 1 1 0 Brinker DNA-binding domain Peptidase_M24 PF00557.24 KXL47317.1 - 9.5e-56 188.8 0.0 1.2e-55 188.4 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF900 PF05990.12 KXL47317.1 - 0.071 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) EF-hand_1 PF00036.32 KXL47318.1 - 8.2e-28 93.9 10.6 1.8e-07 30.2 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KXL47318.1 - 2.9e-24 85.3 11.6 2.2e-14 53.7 1.5 2.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KXL47318.1 - 2.1e-20 70.8 5.5 7.8e-05 22.3 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KXL47318.1 - 4.5e-19 67.0 8.6 2.2e-06 26.9 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KXL47318.1 - 6.5e-14 51.5 9.8 0.0001 22.1 0.6 4.1 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KXL47318.1 - 7.5e-07 29.5 0.1 0.0052 17.1 0.1 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KXL47318.1 - 3.4e-06 27.0 7.4 0.0026 17.7 0.5 3.9 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KXL47318.1 - 0.067 13.4 0.6 0.28 11.4 0.4 2.2 1 1 0 1 1 1 0 Dockerin type I domain DUF1770 PF08589.10 KXL47319.1 - 3.1e-34 117.9 0.5 4e-34 117.5 0.5 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) adh_short PF00106.25 KXL47322.1 - 5e-21 75.1 0.0 3.1e-19 69.2 0.0 2.1 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL47322.1 - 5.4e-12 45.8 0.0 1.6e-11 44.2 0.0 1.7 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL47322.1 - 1.9e-05 24.7 0.0 3.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL47322.1 - 6.4e-05 22.5 0.0 0.00015 21.3 0.0 1.6 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXL47322.1 - 0.0024 17.3 0.0 0.0034 16.8 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 KXL47322.1 - 0.088 12.9 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAA_hydrolase_N PF09298.11 KXL47325.1 - 8.9e-26 90.2 0.0 1.2e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal FAA_hydrolase PF01557.18 KXL47325.1 - 1.4e-13 51.1 0.0 2e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase PF01557.18 KXL47326.1 - 1.4e-25 90.3 0.0 1.6e-25 90.1 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family PQ-loop PF04193.14 KXL47327.1 - 9.3e-24 83.0 7.9 1.9e-13 50.0 1.1 2.7 3 0 0 3 3 3 2 PQ loop repeat SAYSvFN PF10260.9 KXL47327.1 - 0.012 15.5 0.3 1.7 8.6 0.0 2.8 1 1 1 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) HET PF06985.11 KXL47329.1 - 1.2e-21 77.6 0.1 1.8e-21 77.0 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2457 PF10446.9 KXL47330.1 - 5.4e-121 405.0 42.1 5.4e-121 405.0 42.1 3.7 2 2 1 3 3 3 1 Protein of unknown function (DUF2457) Extensin_2 PF04554.13 KXL47330.1 - 0.0036 17.4 29.0 0.0036 17.4 29.0 5.3 4 3 1 5 5 5 2 Extensin-like region DUF3665 PF12427.8 KXL47330.1 - 1.8 8.4 4.9 5.1 6.9 4.9 1.8 1 0 0 1 1 1 0 Branched-chain amino acid aminotransferase Ribosomal_S8 PF00410.19 KXL47334.1 - 8.2e-17 61.3 0.0 2.7e-09 37.0 0.1 3.8 2 1 0 2 2 2 2 Ribosomal protein S8 BRI3BP PF14965.6 KXL47336.1 - 0.0031 17.1 4.8 1 8.9 0.0 2.2 2 0 0 2 2 2 2 Negative regulator of p53/TP53 MAP65_ASE1 PF03999.12 KXL47336.1 - 0.036 12.8 0.1 0.047 12.4 0.1 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF21 PF01595.20 KXL47336.1 - 0.041 13.6 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain MAP17 PF15807.5 KXL47336.1 - 9.1 6.5 7.3 0.79 10.0 0.2 2.1 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Xpo1 PF08389.12 KXL47337.1 - 7.1e-29 100.8 1.0 5.2e-28 98.0 0.0 3.1 3 1 0 3 3 3 1 Exportin 1-like protein Aldedh PF00171.22 KXL47338.1 - 2.9e-182 606.3 2.1 3.2e-182 606.2 2.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family tRNA-synt_2 PF00152.20 KXL47339.1 - 1.4e-91 306.9 0.0 1.9e-91 306.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 KXL47339.1 - 0.071 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.25 KXL47339.1 - 0.095 12.7 0.0 0.18 11.7 0.0 1.7 1 1 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) ANAPC4_WD40 PF12894.7 KXL47340.1 - 0.0022 18.3 0.3 2.4 8.5 0.0 4.0 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 KXL47340.1 - 0.03 13.6 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller WD40 PF00400.32 KXL47340.1 - 0.049 14.5 0.2 7.6 7.6 0.0 4.3 4 0 0 4 4 4 0 WD domain, G-beta repeat NHL PF01436.21 KXL47340.1 - 0.2 11.8 0.8 15 5.8 0.0 3.0 3 0 0 3 3 3 0 NHL repeat p450 PF00067.22 KXL47341.1 - 9.2e-61 206.0 0.0 1.3e-60 205.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.32 KXL47342.1 - 3.7e-24 84.5 13.8 9.9e-07 29.4 0.0 7.0 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL47342.1 - 2.9e-08 33.9 0.0 0.0057 16.9 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1513 PF07433.11 KXL47342.1 - 0.0078 15.3 0.3 0.1 11.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1513) eIF2A PF08662.11 KXL47342.1 - 0.011 15.6 0.0 1.6 8.6 0.0 2.9 2 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KXL47342.1 - 0.082 11.5 0.1 0.9 8.1 0.0 2.3 1 1 1 2 2 2 0 Nucleoporin Nup120/160 GTP_EFTU PF00009.27 KXL47343.1 - 2.2e-56 190.5 0.1 3.5e-56 189.8 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KXL47343.1 - 9.8e-35 119.0 0.0 1.9e-34 118.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 KXL47343.1 - 2.3e-31 107.7 0.0 5e-31 106.6 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KXL47343.1 - 5.3e-23 80.9 0.0 1.3e-22 79.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KXL47343.1 - 1.1e-13 51.4 0.3 3.8e-13 49.6 0.2 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KXL47343.1 - 9.9e-05 22.2 0.0 0.00031 20.6 0.0 1.8 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 KXL47343.1 - 0.095 12.8 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase ANAPC4_WD40 PF12894.7 KXL47344.1 - 0.0002 21.6 0.1 0.016 15.5 0.0 3.1 2 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXL47344.1 - 0.0013 19.5 4.0 0.21 12.5 0.0 4.1 5 0 0 5 5 5 2 WD domain, G-beta repeat WD40_like PF17005.5 KXL47344.1 - 0.16 11.3 0.1 0.24 10.7 0.1 1.2 1 0 0 1 1 1 0 WD40-like domain Cu-oxidase_2 PF07731.14 KXL47345.1 - 9.1e-22 77.3 3.9 5.2e-19 68.3 2.8 2.7 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXL47345.1 - 1.3e-17 63.9 1.4 2.5e-17 63.0 0.7 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 KXL47345.1 - 0.0016 18.6 0.1 0.0065 16.6 0.0 2.2 2 0 0 2 2 2 1 Multicopper oxidase MFS_1 PF07690.16 KXL47346.1 - 7e-37 127.2 23.3 7e-37 127.2 23.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXL47346.1 - 0.0014 17.2 0.8 0.0014 17.2 0.8 2.9 3 0 0 3 3 3 2 Fungal trichothecene efflux pump (TRI12) VanZ PF04892.12 KXL47346.1 - 0.0085 16.8 0.0 0.035 14.8 0.0 2.0 1 0 0 1 1 1 1 VanZ like family LSM PF01423.22 KXL47347.1 - 1.3e-10 40.8 0.0 1.5e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXL47347.1 - 0.037 14.2 0.0 0.063 13.4 0.0 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain DUF150_C PF17384.2 KXL47347.1 - 0.11 12.7 0.0 0.27 11.4 0.0 1.7 2 0 0 2 2 2 0 RimP C-terminal SH3 domain Glyco_hydro_64 PF16483.5 KXL47347.1 - 0.17 11.1 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 Beta-1,3-glucanase DUF2264 PF10022.9 KXL47348.1 - 4.6e-136 453.6 0.0 5.5e-136 453.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Glyco_tran_28_C PF04101.16 KXL47348.1 - 0.26 11.3 0.1 0.47 10.4 0.1 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Aldedh PF00171.22 KXL47349.1 - 1.1e-164 548.3 0.8 1.3e-164 548.1 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TetR_N PF00440.23 KXL47349.1 - 0.092 12.6 0.1 6.1 6.7 0.0 3.1 3 0 0 3 3 3 0 Bacterial regulatory proteins, tetR family MA3 PF02847.17 KXL47351.1 - 1.9e-25 89.0 0.1 4.9e-25 87.7 0.0 1.8 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 KXL47351.1 - 1.8e-11 44.1 1.0 2.9e-11 43.4 1.0 1.4 1 0 0 1 1 1 1 MIF4G domain DUF2196 PF09962.9 KXL47352.1 - 6.4e-24 83.7 3.8 1.2e-23 82.8 3.8 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) zf-Di19 PF05605.12 KXL47352.1 - 0.017 15.4 0.4 0.031 14.6 0.1 1.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding UPF0547 PF10571.9 KXL47352.1 - 0.1 12.7 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 Rdx PF10262.9 KXL47353.1 - 1.7e-31 108.2 0.0 1.7e-31 108.2 0.0 1.4 2 0 0 2 2 2 1 Rdx family Fungal_trans PF04082.18 KXL47354.1 - 1.1e-17 64.0 0.1 2.1e-17 63.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL47354.1 - 4.1e-07 30.0 8.3 8.6e-07 29.0 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cwf_Cwc_15 PF04889.12 KXL47354.1 - 0.29 10.8 10.3 0.71 9.6 6.9 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein TFIIA PF03153.13 KXL47354.1 - 8.8 6.2 19.7 17 5.3 19.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1348 PF07080.11 KXL47355.1 - 5.1e-61 204.3 9.8 5.8e-61 204.1 9.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 KXL47355.1 - 0.0023 18.6 0.1 0.003 18.2 0.1 1.4 1 1 0 1 1 1 1 SnoaL-like domain Beta_elim_lyase PF01212.21 KXL47356.1 - 2.7e-67 227.1 0.0 3.2e-67 226.9 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KXL47356.1 - 0.24 9.9 0.0 0.42 9.1 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Robl_LC7 PF03259.17 KXL47357.1 - 1e-07 31.6 0.1 0.0002 21.0 0.0 2.2 2 0 0 2 2 2 2 Roadblock/LC7 domain Ipi1_N PF12333.8 KXL47358.1 - 4.7e-23 81.7 1.2 2.2e-22 79.6 0.2 2.3 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation CaM_binding PF07839.11 KXL47358.1 - 0.0072 17.1 2.8 0.0072 17.1 2.8 1.6 2 0 0 2 2 2 1 Plant calmodulin-binding domain Pep1_7 PF17232.2 KXL47358.1 - 0.1 13.1 0.9 0.46 11.0 0.0 2.4 3 0 0 3 3 3 0 Elicitor peptide 1-7 Sec10 PF07393.11 KXL47359.1 - 1.6e-204 681.4 0.0 2e-204 681.1 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 Spore_III_AB PF09548.10 KXL47359.1 - 0.2 11.8 2.4 4.5 7.4 0.0 3.3 3 1 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) FAM184 PF15665.5 KXL47360.1 - 0.05 13.4 1.4 0.099 12.4 1.4 1.6 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Sugarporin_N PF11471.8 KXL47360.1 - 0.31 11.0 9.0 24 5.0 0.0 4.3 4 0 0 4 4 4 0 Maltoporin periplasmic N-terminal extension ATG2_CAD PF13329.6 KXL47361.1 - 0.092 12.5 0.1 0.11 12.3 0.1 1.0 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif tRNA-synt_2 PF00152.20 KXL47362.1 - 4.7e-72 242.7 0.0 7.9e-72 242.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 KXL47362.1 - 1.4e-14 53.8 0.0 2.2e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 KXL47362.1 - 1.7e-07 31.1 0.3 3.8e-07 30.0 0.0 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KXL47362.1 - 0.0023 17.5 0.5 1.3 8.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF3395 PF11875.8 KXL47362.1 - 0.19 11.6 3.2 0.33 10.8 3.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) Fungal_trans PF04082.18 KXL47363.1 - 3.6e-14 52.4 0.0 5.8e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL47363.1 - 7.1e-06 26.1 12.5 1.1e-05 25.4 12.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.12 KXL47363.1 - 0.17 11.8 0.0 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 Heat shock factor binding protein 1 FAD_binding_3 PF01494.19 KXL47364.1 - 2.9e-13 49.8 0.3 7.6e-12 45.1 0.3 2.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXL47364.1 - 5.4e-07 29.1 0.2 0.0017 17.6 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXL47364.1 - 1.2e-05 25.4 0.2 2.7e-05 24.3 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXL47364.1 - 5.4e-05 23.7 0.1 0.0019 18.7 0.1 3.0 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXL47364.1 - 9.3e-05 21.7 0.1 0.00019 20.6 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXL47364.1 - 9.6e-05 22.1 0.8 0.0032 17.1 0.2 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 KXL47364.1 - 0.0026 16.9 0.4 0.0059 15.7 0.2 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 KXL47364.1 - 0.003 16.3 0.0 0.039 12.7 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 KXL47364.1 - 0.14 11.4 0.1 0.22 10.8 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAT PF04768.13 KXL47365.1 - 4.3e-50 169.7 0.2 9.8e-50 168.5 0.1 1.7 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 KXL47365.1 - 6.2e-33 113.8 0.0 2.5e-32 111.9 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 KXL47365.1 - 1.7e-30 106.4 1.0 2.2e-30 106.0 0.1 1.6 2 0 0 2 2 2 1 Amino acid kinase family Sacchrp_dh_NADP PF03435.18 KXL47365.1 - 0.0044 17.3 0.0 0.02 15.2 0.0 2.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 KXL47365.1 - 0.039 14.1 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Corona_S2 PF01601.16 KXL47366.1 - 0.0061 15.1 10.4 0.0079 14.7 10.4 1.0 1 0 0 1 1 1 1 Coronavirus S2 glycoprotein Tannase PF07519.11 KXL47367.1 - 3.4e-106 356.0 0.2 4.1e-106 355.7 0.2 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KXL47367.1 - 0.036 13.3 0.0 0.11 11.7 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 PapC_C PF13953.6 KXL47368.1 - 0.039 13.8 0.0 0.29 11.0 0.0 2.0 2 0 0 2 2 2 0 PapC C-terminal domain LSM PF01423.22 KXL47369.1 - 2.7e-18 65.4 0.5 3.7e-18 65.0 0.5 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KXL47369.1 - 0.091 12.4 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Hfq protein Ribul_P_3_epim PF00834.19 KXL47370.1 - 1.6e-62 210.4 0.1 1.9e-61 206.9 0.1 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 KXL47370.1 - 0.021 14.6 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain OMPdecase PF00215.24 KXL47370.1 - 0.043 13.4 0.1 0.065 12.8 0.1 1.5 1 1 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family AhpC-TSA PF00578.21 KXL47370.1 - 0.18 11.7 0.4 1.1 9.2 0.4 2.0 1 1 0 1 1 1 0 AhpC/TSA family Methyltransf_11 PF08241.12 KXL47371.1 - 1.2e-09 38.7 0.0 5e-09 36.7 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL47371.1 - 0.0016 19.1 0.0 0.0062 17.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL47371.1 - 0.08 13.7 0.0 0.27 12.0 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain VGCC_beta4Aa_N PF12052.8 KXL47371.1 - 8.6 6.6 6.4 0.99 9.6 0.5 2.3 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal SH3BGR PF04908.15 KXL47373.1 - 6.3e-05 23.1 0.0 0.00012 22.1 0.0 1.4 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 KXL47373.1 - 0.024 14.9 0.0 0.052 13.8 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin bZIP_1 PF00170.21 KXL47374.1 - 2.9e-05 24.1 9.0 5.4e-05 23.2 9.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor DUF1635 PF07795.11 KXL47374.1 - 0.062 13.2 2.2 0.13 12.1 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF3053 PF11254.8 KXL47374.1 - 0.066 12.8 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) bZIP_2 PF07716.15 KXL47374.1 - 0.1 12.7 9.5 0.04 14.0 6.4 1.9 1 1 1 2 2 2 0 Basic region leucine zipper bZIP_Maf PF03131.17 KXL47374.1 - 7.9 7.1 10.8 1.6 9.3 7.1 1.7 2 0 0 2 2 2 0 bZIP Maf transcription factor Acyltransferase PF01553.21 KXL47375.1 - 1.3e-18 66.9 0.0 1.7e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KXL47375.1 - 1.8e-07 31.2 0.2 4.4e-07 29.9 0.2 1.7 1 0 0 1 1 1 1 Acyltransferase C-terminus F-box-like PF12937.7 KXL47377.1 - 0.036 13.9 0.0 0.75 9.7 0.0 2.7 2 0 0 2 2 2 0 F-box-like CBF PF03914.17 KXL47378.1 - 4.9e-35 121.1 0.7 1.2e-34 119.9 0.7 1.7 1 0 0 1 1 1 1 CBF/Mak21 family Bt_P21 PF05560.11 KXL47378.1 - 0.06 12.9 0.0 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 Bacillus thuringiensis P21 molecular chaperone protein Mt_ATP-synt_B PF05405.14 KXL47379.1 - 1.2e-50 171.3 6.3 1.5e-50 171.0 6.3 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) PLU-1 PF08429.11 KXL47379.1 - 0.083 12.0 4.0 0.11 11.6 4.0 1.1 1 0 0 1 1 1 0 PLU-1-like protein A_deaminase PF00962.22 KXL47380.1 - 7e-123 410.1 0.1 4.7e-122 407.4 0.2 2.1 2 0 0 2 2 2 1 Adenosine/AMP deaminase Bromo_TP PF07524.13 KXL47381.1 - 2.5e-07 30.6 0.0 3.7e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 KXL47381.1 - 0.0075 16.3 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Ank_2 PF12796.7 KXL47382.1 - 5.7e-22 78.1 0.0 1.8e-12 47.7 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXL47382.1 - 1.4e-17 63.8 0.9 2.9e-06 27.7 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXL47382.1 - 4.3e-16 58.8 0.6 7.2e-07 29.4 0.4 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KXL47382.1 - 5.7e-16 58.2 1.8 8.7e-05 22.8 0.2 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KXL47382.1 - 1.3e-14 52.9 0.1 0.00055 20.2 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat ABC_tran PF00005.27 KXL47383.1 - 5.3e-27 95.0 0.1 1.1e-26 93.9 0.0 1.6 2 0 0 2 2 2 1 ABC transporter ABC2_membrane PF01061.24 KXL47383.1 - 1.2e-14 54.2 10.8 1.2e-14 54.2 10.8 2.3 3 0 0 3 3 3 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 KXL47383.1 - 0.00028 20.1 10.0 0.00073 18.8 10.0 1.7 1 0 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KXL47383.1 - 0.00089 19.2 0.2 0.0016 18.4 0.2 1.3 1 0 0 1 1 1 1 RsgA GTPase RNA_helicase PF00910.22 KXL47383.1 - 0.0029 18.0 1.0 1.2 9.6 0.0 2.4 2 0 0 2 2 2 2 RNA helicase AAA_21 PF13304.6 KXL47383.1 - 0.018 14.9 0.0 0.25 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KXL47383.1 - 0.052 13.6 0.3 0.1 12.7 0.3 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.23 KXL47383.1 - 0.069 13.2 0.3 0.13 12.3 0.3 1.4 1 0 0 1 1 1 0 Dynamin family SbcCD_C PF13558.6 KXL47383.1 - 0.16 12.2 0.0 0.38 11.0 0.0 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KXL47383.1 - 0.22 11.3 0.6 0.49 10.2 0.6 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 KXL47383.1 - 0.47 10.5 1.4 0.87 9.6 1.4 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain F-box PF00646.33 KXL47385.1 - 1.3e-05 24.9 1.2 4.8e-05 23.1 1.2 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXL47385.1 - 0.002 18.0 3.1 0.0065 16.3 0.5 2.6 2 0 0 2 2 2 1 F-box-like PRANC PF09372.10 KXL47385.1 - 0.13 12.6 0.1 0.44 10.9 0.1 1.9 1 0 0 1 1 1 0 PRANC domain Abhydrolase_1 PF00561.20 KXL47386.1 - 5.3e-15 55.7 0.0 5e-13 49.3 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXL47386.1 - 2e-13 51.5 0.2 4.6e-13 50.3 0.0 1.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXL47386.1 - 9.3e-08 31.6 0.0 2e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 EthD PF07110.11 KXL47386.1 - 0.00073 20.6 0.2 0.2 12.8 0.0 2.9 3 0 0 3 3 3 1 EthD domain Esterase PF00756.20 KXL47386.1 - 0.0011 18.7 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Putative esterase zf-C2H2 PF00096.26 KXL47388.1 - 4.8e-09 36.2 12.2 0.00033 20.9 2.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXL47388.1 - 3.4e-07 30.4 9.8 5.9e-05 23.3 2.5 3.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXL47388.1 - 0.0001 22.8 11.5 0.069 14.0 2.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KXL47388.1 - 0.017 15.5 4.5 0.052 14.0 2.3 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXL47388.1 - 0.021 15.1 4.2 0.044 14.1 0.8 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Rpr2 PF04032.16 KXL47388.1 - 0.03 14.6 0.4 0.046 14.0 0.4 1.5 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2H2_6 PF13912.6 KXL47388.1 - 0.071 13.1 1.0 0.071 13.1 1.0 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KXL47388.1 - 0.12 12.5 2.2 0.97 9.6 0.7 2.3 1 1 1 2 2 2 0 Zinc ribbon domain Pap_E4 PF02711.14 KXL47388.1 - 2.2 9.3 7.8 0.77 10.8 4.6 1.9 2 0 0 2 2 2 0 E4 protein Gln-synt_C PF00120.24 KXL47391.1 - 1.5e-82 277.3 0.0 1.9e-82 277.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain DUF1201 PF06716.11 KXL47391.1 - 0.064 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1201) adh_short_C2 PF13561.6 KXL47392.1 - 5.5e-58 196.3 0.5 6.3e-58 196.1 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL47392.1 - 8.7e-40 136.3 0.1 1.1e-39 135.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL47392.1 - 2.9e-08 33.8 0.9 4.6e-08 33.2 0.9 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KXL47392.1 - 0.0025 17.7 0.2 0.0041 17.0 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KXL47392.1 - 0.0087 15.2 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.19 KXL47392.1 - 0.049 13.0 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Methyltransf_25 PF13649.6 KXL47392.1 - 0.062 14.0 0.0 0.12 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ChuX_HutX PF06228.13 KXL47392.1 - 0.097 12.4 0.0 6.3 6.6 0.0 2.2 2 0 0 2 2 2 0 Haem utilisation ChuX/HutX GDP_Man_Dehyd PF16363.5 KXL47392.1 - 0.1 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXL47392.1 - 0.17 10.9 0.0 0.29 10.1 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Abhydrolase_2 PF02230.16 KXL47393.1 - 8.3e-56 189.2 0.0 9.4e-56 189.0 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KXL47393.1 - 4.1e-06 27.6 1.6 5.6e-06 27.1 1.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXL47393.1 - 1.2e-05 25.0 0.0 0.00033 20.2 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KXL47393.1 - 1.6e-05 24.3 0.1 0.1 11.8 0.0 2.8 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KXL47393.1 - 7.1e-05 22.8 0.3 0.11 12.3 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 KXL47393.1 - 0.0058 16.2 0.0 0.01 15.4 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KXL47393.1 - 0.026 14.2 0.2 2.2 7.8 0.1 2.7 2 1 1 3 3 3 0 alpha/beta hydrolase fold Cutinase PF01083.22 KXL47393.1 - 0.066 13.2 0.0 0.092 12.7 0.0 1.2 1 0 0 1 1 1 0 Cutinase Lipase_3 PF01764.25 KXL47393.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) LigB PF02900.18 KXL47394.1 - 7.8e-30 103.9 0.0 9.2e-30 103.6 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase L51_S25_CI-B8 PF05047.16 KXL47395.1 - 5.8e-16 58.2 0.0 7.3e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MPC PF03650.13 KXL47396.1 - 2.3e-47 159.7 0.7 3.7e-47 159.0 0.2 1.5 2 0 0 2 2 2 1 Mitochondrial pyruvate carriers adh_short PF00106.25 KXL47397.1 - 3.8e-06 26.5 0.0 0.011 15.2 0.0 3.1 2 1 1 3 3 3 3 short chain dehydrogenase KR PF08659.10 KXL47397.1 - 0.0043 17.0 0.0 0.0091 15.9 0.0 1.6 1 0 0 1 1 1 1 KR domain zf-CCCH PF00642.24 KXL47398.1 - 4.1e-15 55.3 26.4 4.5e-05 23.2 1.5 6.2 6 0 0 6 6 6 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KXL47398.1 - 1.7e-08 34.2 42.2 0.005 16.8 1.6 6.6 7 1 0 7 7 7 4 Zinc finger domain zf-CCCH_4 PF18044.1 KXL47398.1 - 5.2e-06 26.1 6.8 0.00073 19.3 0.6 5.4 5 1 0 5 5 5 2 CCCH-type zinc finger Torus PF16131.5 KXL47398.1 - 0.0019 18.9 24.6 0.22 12.2 0.6 5.1 1 1 3 4 4 4 3 Torus domain zf-CCCH_3 PF15663.5 KXL47398.1 - 0.38 11.0 16.2 0.08 13.2 3.4 3.2 1 1 2 3 3 3 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 KXL47398.1 - 2.2 8.9 27.4 1.6 9.3 1.1 4.7 4 0 0 4 4 4 0 RNA-binding, Nab2-type zinc finger Rad17 PF03215.15 KXL47399.1 - 3.2e-28 98.9 0.0 6.1e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 KXL47399.1 - 0.0018 18.7 0.0 0.0041 17.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXL47399.1 - 0.006 17.0 0.0 0.017 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KXL47399.1 - 0.0068 17.0 0.0 0.02 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXL47399.1 - 0.007 16.7 0.0 0.019 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KXL47399.1 - 0.012 15.5 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase RuvB_N PF05496.12 KXL47399.1 - 0.029 14.1 0.0 0.096 12.4 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 KXL47399.1 - 0.042 13.6 0.0 0.094 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KXL47399.1 - 0.12 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein TP53IP5 PF15331.6 KXL47399.1 - 3.5 7.7 6.5 6.4 6.9 6.5 1.4 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 WD40 PF00400.32 KXL47401.1 - 4.9e-39 131.6 19.0 6e-10 39.6 0.2 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL47401.1 - 1.1e-12 48.1 0.9 0.0045 17.3 0.0 5.2 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXL47401.1 - 2.2e-09 36.7 0.3 0.14 11.1 0.0 4.4 2 2 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KXL47401.1 - 6.8e-06 25.0 5.4 0.023 13.4 0.1 4.8 3 1 1 5 5 5 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.14 KXL47401.1 - 0.0068 15.5 0.0 0.015 14.4 0.0 1.6 1 1 0 1 1 1 1 Coatomer WD associated region DUF2796 PF10986.8 KXL47401.1 - 0.041 13.8 0.9 0.07 13.1 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Frtz PF11768.8 KXL47401.1 - 0.049 12.0 0.0 0.11 10.8 0.0 1.5 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz PALB2_WD40 PF16756.5 KXL47401.1 - 0.052 12.5 0.1 0.052 12.5 0.1 2.6 4 0 0 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Urease_linker PF18473.1 KXL47401.1 - 0.073 13.0 2.3 0.16 11.9 2.3 1.5 1 0 0 1 1 1 0 Urease subunit beta-alpha linker domain AAA_12 PF13087.6 KXL47402.1 - 1.8e-26 93.0 0.0 3e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXL47402.1 - 2.4e-24 86.5 0.0 4.3e-24 85.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXL47402.1 - 1.4e-09 37.9 0.0 9.8e-05 22.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KXL47402.1 - 1.3e-07 32.0 0.0 4.9e-07 30.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KXL47402.1 - 1.5e-06 28.3 0.0 3.1e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DnaB_C PF03796.15 KXL47402.1 - 0.00033 20.1 0.0 0.00053 19.4 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 KXL47402.1 - 0.0018 18.7 0.3 0.0064 16.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain UvrD_C_2 PF13538.6 KXL47402.1 - 0.0026 17.6 0.0 0.006 16.4 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA PF00004.29 KXL47402.1 - 0.0039 17.6 0.0 0.012 16.0 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KXL47402.1 - 0.0055 17.1 0.0 0.32 11.4 0.0 3.0 3 0 0 3 3 3 1 RNA helicase DEAD PF00270.29 KXL47402.1 - 0.0065 16.2 0.1 0.018 14.8 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_5 PF07728.14 KXL47402.1 - 0.0088 16.0 0.0 0.086 12.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) UvrD-helicase PF00580.21 KXL47402.1 - 0.013 15.0 0.0 0.02 14.4 0.0 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain RecA PF00154.21 KXL47402.1 - 0.025 14.0 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein Viral_helicase1 PF01443.18 KXL47402.1 - 0.029 14.1 0.1 19 4.9 0.0 3.2 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KXL47402.1 - 0.032 13.5 0.8 0.094 11.9 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KXL47402.1 - 0.042 14.1 0.2 0.18 12.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.15 KXL47402.1 - 0.05 12.4 0.0 0.084 11.7 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein Helicase_RecD PF05127.14 KXL47402.1 - 0.11 12.4 0.0 0.62 9.9 0.0 2.0 2 0 0 2 2 2 0 Helicase SMC_N PF02463.19 KXL47402.1 - 0.16 11.4 0.0 0.16 11.3 0.0 1.4 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain 4HBT PF03061.22 KXL47403.1 - 6.8e-13 48.8 0.1 9.3e-13 48.3 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KXL47403.1 - 0.0021 18.4 0.0 0.0023 18.2 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily MaoC_dehydratas PF01575.19 KXL47404.1 - 7e-22 77.3 0.0 1.1e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KXL47404.1 - 0.00016 21.8 0.0 0.014 15.6 0.0 2.4 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase PBP PF01161.20 KXL47405.1 - 5.4e-14 52.6 0.0 7e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Retinal PF15449.6 KXL47406.1 - 0.73 7.5 5.5 0.88 7.3 5.5 1.0 1 0 0 1 1 1 0 Retinal protein Epimerase PF01370.21 KXL47407.1 - 1.1e-15 57.8 0.0 1.5e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KXL47407.1 - 1.1e-09 37.9 0.0 0.00012 21.3 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 KXL47407.1 - 1.2e-09 37.6 0.0 1.7e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXL47407.1 - 2e-09 37.3 0.0 4e-09 36.3 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KXL47407.1 - 8.1e-06 25.8 0.0 1.7e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXL47407.1 - 0.00031 20.4 0.5 0.0098 15.5 0.2 2.3 2 1 0 2 2 2 1 NmrA-like family KR PF08659.10 KXL47407.1 - 0.00053 19.9 0.0 0.00094 19.1 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KXL47407.1 - 0.0011 18.4 0.0 0.01 15.3 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KXL47407.1 - 0.0094 15.1 0.1 0.023 13.8 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KXL47407.1 - 0.052 12.6 0.0 0.12 11.4 0.0 1.7 1 1 0 1 1 1 0 RmlD substrate binding domain MFS_1 PF07690.16 KXL47409.1 - 2e-29 102.6 65.8 6.1e-23 81.3 32.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Arf PF00025.21 KXL47410.1 - 5.8e-75 250.6 0.1 6.5e-75 250.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KXL47410.1 - 8.2e-15 55.1 0.0 1.1e-14 54.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KXL47410.1 - 1.1e-12 47.7 0.0 1.4e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KXL47410.1 - 2.2e-11 43.6 0.0 2.6e-11 43.4 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KXL47410.1 - 5.5e-11 42.2 0.3 8.3e-07 28.5 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KXL47410.1 - 2.6e-09 36.8 0.0 3.4e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXL47410.1 - 1.1e-06 28.7 0.0 1.9e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXL47410.1 - 0.00087 18.9 0.0 0.068 12.7 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 KXL47410.1 - 0.0016 17.5 0.2 0.0059 15.6 0.1 1.9 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 KXL47410.1 - 0.011 15.2 0.6 0.039 13.5 0.6 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B Flg_hook PF02120.16 KXL47410.1 - 0.11 12.3 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK AAA_18 PF13238.6 KXL47410.1 - 0.15 12.6 0.2 0.3 11.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain VWA_3 PF13768.6 KXL47410.1 - 0.16 11.9 0.0 3 7.8 0.0 2.1 2 0 0 2 2 2 0 von Willebrand factor type A domain Helicase_C PF00271.31 KXL47411.1 - 1.7e-15 57.3 0.1 8.7e-15 55.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.23 KXL47411.1 - 9.9e-13 48.3 0.1 3.9e-12 46.4 0.1 2.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KXL47411.1 - 3.3e-09 37.0 0.0 9.2e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KXL47411.1 - 5.3e-08 32.8 0.0 1.6e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 KXL47411.1 - 7.7e-05 23.1 0.0 0.00054 20.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Dicer_dimer PF03368.14 KXL47411.1 - 0.0047 17.1 1.0 11 6.3 0.0 4.5 4 0 0 4 4 4 1 Dicer dimerisation domain FtsK_SpoIIIE PF01580.18 KXL47411.1 - 0.0052 16.2 0.0 0.014 14.8 0.0 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family BCS1_N PF08740.11 KXL47412.1 - 4.8e-40 137.5 0.1 8.3e-40 136.8 0.1 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KXL47412.1 - 3.8e-19 69.4 0.0 1.1e-18 68.0 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXL47412.1 - 0.00013 22.0 0.0 0.00034 20.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXL47412.1 - 0.00033 21.1 0.2 0.0012 19.2 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain AAA_7 PF12775.7 KXL47412.1 - 0.0016 18.0 0.0 0.018 14.6 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 KXL47412.1 - 0.0046 17.1 0.0 0.012 15.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KXL47412.1 - 0.0046 17.3 0.0 0.056 13.8 0.0 2.4 2 0 0 2 2 2 1 RNA helicase RuvB_N PF05496.12 KXL47412.1 - 0.0051 16.6 0.0 0.0096 15.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KXL47412.1 - 0.0069 16.1 0.0 0.049 13.3 0.0 2.2 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 KXL47412.1 - 0.0093 15.6 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KXL47412.1 - 0.01 15.2 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 KaiC DUF815 PF05673.13 KXL47412.1 - 0.018 14.2 0.0 0.03 13.5 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 KXL47412.1 - 0.022 15.0 0.0 0.073 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXL47412.1 - 0.023 15.2 0.0 0.053 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KXL47412.1 - 0.025 14.4 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KXL47412.1 - 0.07 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PPV_E1_C PF00519.17 KXL47412.1 - 0.086 11.7 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase AAA_28 PF13521.6 KXL47412.1 - 0.092 13.0 0.0 0.38 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KXL47412.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 KXL47412.1 - 0.17 11.8 0.0 0.77 9.7 0.0 2.1 2 0 0 2 2 2 0 NACHT domain DUF2922 PF11148.8 KXL47413.1 - 0.19 11.5 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) DUF3419 PF11899.8 KXL47414.1 - 5.8e-150 499.8 0.0 9.6e-150 499.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 KXL47414.1 - 1.4e-07 31.5 0.0 3.4e-07 30.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL47414.1 - 2.8e-07 31.1 0.0 4.2e-06 27.4 0.0 2.9 3 1 1 4 4 4 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL47414.1 - 8.6e-07 29.6 0.0 4.4e-06 27.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL47414.1 - 1.8e-05 25.3 0.0 0.0012 19.4 0.0 3.6 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL47414.1 - 5e-05 23.1 0.0 0.0027 17.5 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXL47414.1 - 0.00085 18.7 0.0 0.14 11.5 0.0 2.9 2 1 1 3 3 3 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KXL47414.1 - 0.015 14.8 0.0 0.043 13.3 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase PCMT PF01135.19 KXL47414.1 - 0.021 14.6 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NADH-u_ox-rdase PF10785.9 KXL47415.1 - 1.7e-28 99.1 0.1 3.4e-28 98.2 0.1 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 KXL47415.1 - 4.6e-27 93.8 0.1 6.8e-27 93.3 0.1 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Aquarius_N PF16399.5 KXL47416.1 - 1.9e-302 1005.3 0.0 2.3e-302 1005.0 0.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_11 PF13086.6 KXL47416.1 - 7.1e-10 39.1 0.1 1.7e-09 37.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KXL47416.1 - 3.1e-06 27.6 0.1 1.6e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KXL47416.1 - 3.2e-06 27.2 0.0 7.2e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KXL47416.1 - 0.00016 21.5 0.0 0.00029 20.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 KXL47416.1 - 0.00039 19.8 0.0 0.00099 18.5 0.0 1.6 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 KXL47416.1 - 0.00065 20.1 0.2 0.042 14.2 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KXL47416.1 - 0.0024 18.3 0.0 0.024 15.1 0.0 2.7 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 KXL47416.1 - 0.03 14.1 0.1 0.062 13.1 0.1 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase UvrD-helicase PF00580.21 KXL47416.1 - 0.039 13.5 0.0 0.081 12.4 0.0 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Adeno_IVa2 PF02456.15 KXL47416.1 - 0.043 12.6 0.0 0.074 11.8 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_22 PF13401.6 KXL47416.1 - 0.048 13.9 0.0 0.25 11.6 0.0 2.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KXL47416.1 - 0.063 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 KXL47416.1 - 0.087 12.0 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 KXL47416.1 - 0.15 11.7 0.0 0.45 10.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain SAP PF02037.27 KXL47416.1 - 0.21 11.4 1.1 0.45 10.3 0.4 2.0 2 0 0 2 2 2 0 SAP domain AF-4 PF05110.13 KXL47417.1 - 0.15 10.1 1.0 0.18 9.9 1.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein AAA_2 PF07724.14 KXL47418.1 - 1.1e-37 129.7 0.0 1.8e-37 129.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.9 KXL47418.1 - 9.5e-27 92.9 0.5 2e-26 91.8 0.2 1.8 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KXL47418.1 - 0.00055 19.9 0.0 0.0016 18.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Cathelicidins PF00666.17 KXL47419.1 - 0.008 16.5 0.9 0.0096 16.2 0.9 1.2 1 0 0 1 1 1 1 Cathelicidin Cyt-b5 PF00173.28 KXL47420.1 - 7.6e-11 42.0 0.1 9e-11 41.8 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3987 PF13148.6 KXL47420.1 - 0.14 11.2 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) MFS_1 PF07690.16 KXL47421.1 - 3.4e-35 121.6 27.0 3.4e-35 121.6 27.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL47421.1 - 8.8e-10 38.0 5.4 8.8e-10 38.0 5.4 2.5 2 2 0 2 2 2 1 Sugar (and other) transporter Phage_holin_5_2 PF16079.5 KXL47421.1 - 0.4 11.0 0.1 0.4 11.0 0.1 4.3 3 2 2 5 5 5 0 Phage holin family Hol44, in holin superfamily V Arginase PF00491.21 KXL47422.1 - 2.7e-84 283.0 0.1 3.4e-84 282.7 0.1 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KXL47422.1 - 0.17 12.1 0.2 0.28 11.4 0.2 1.3 1 0 0 1 1 1 0 UPF0489 domain RRM_1 PF00076.22 KXL47423.1 - 9.3e-58 192.0 0.0 1.2e-17 63.4 0.0 5.2 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 KXL47423.1 - 0.0079 16.0 0.2 1.8 8.4 0.0 3.2 2 2 2 4 4 4 1 Rrp7 RRM-like N-terminal domain Nup35_RRM_2 PF14605.6 KXL47423.1 - 0.021 14.8 0.3 14 5.8 0.0 3.4 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KXL47423.1 - 0.071 12.7 0.0 6.9 6.3 0.0 2.4 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M49 PF03571.15 KXL47424.1 - 8.4e-242 803.4 0.0 9.8e-242 803.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 2C_adapt PF08793.10 KXL47424.1 - 0.12 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 2-cysteine adaptor domain Methyltransf_25 PF13649.6 KXL47425.1 - 1.8e-20 73.5 0.0 3.2e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL47425.1 - 2e-18 66.8 0.0 3.3e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL47425.1 - 1.8e-17 63.5 0.0 2.3e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXL47425.1 - 3.7e-11 43.1 0.0 5.2e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL47425.1 - 8.8e-11 42.4 0.0 1.5e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXL47425.1 - 3.5e-08 33.1 0.0 6.6e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXL47425.1 - 5e-05 22.9 0.0 7.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KXL47425.1 - 6.1e-05 22.9 0.0 9.4e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 KXL47425.1 - 0.00055 19.9 0.0 0.00083 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KXL47425.1 - 0.0036 17.3 0.0 0.0062 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXL47425.1 - 0.0037 16.6 0.0 0.006 15.9 0.0 1.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 KXL47425.1 - 0.0066 15.9 0.1 0.017 14.6 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.13 KXL47425.1 - 0.0088 15.5 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_29 PF03141.16 KXL47425.1 - 0.07 11.7 0.0 0.16 10.5 0.0 1.7 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase CheR PF01739.18 KXL47425.1 - 0.12 11.8 0.0 3.1 7.2 0.0 2.1 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain NAD_binding_5 PF07994.12 KXL47427.1 - 4.4e-144 479.8 0.0 5.2e-144 479.5 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KXL47427.1 - 4.5e-45 152.4 0.7 8.2e-45 151.5 0.7 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase NAGLU_N PF12971.7 KXL47428.1 - 0.15 11.9 1.4 2.6 7.9 0.1 2.3 2 0 0 2 2 2 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain BetaGal_dom4_5 PF13364.6 KXL47429.1 - 0.0014 19.1 0.0 0.0019 18.7 0.0 1.1 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain NFACT-R_1 PF05670.13 KXL47430.1 - 3.2e-42 143.6 0.0 5.7e-42 142.8 0.0 1.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain LMBR1 PF04791.16 KXL47430.1 - 1.3 7.8 3.6 1.4 7.7 3.6 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein adh_short PF00106.25 KXL47431.1 - 5.3e-23 81.5 0.0 2.8e-22 79.1 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL47431.1 - 9.3e-17 61.4 0.1 1.8e-15 57.2 0.1 2.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL47431.1 - 4.9e-09 36.3 0.0 2.5e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 KR domain 3HCDH_N PF02737.18 KXL47431.1 - 0.0007 19.5 0.1 0.0014 18.6 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KXL47431.1 - 0.0029 16.9 0.0 0.0045 16.3 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ADH_zinc_N PF00107.26 KXL47431.1 - 0.029 14.4 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_7 PF13241.6 KXL47431.1 - 0.053 14.0 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding CoA_binding_2 PF13380.6 KXL47431.1 - 0.078 13.5 0.0 0.23 11.9 0.0 1.8 2 0 0 2 2 2 0 CoA binding domain YjeF_N PF03853.15 KXL47431.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus NAD_binding_10 PF13460.6 KXL47431.1 - 0.13 12.1 0.1 0.39 10.6 0.0 1.8 2 0 0 2 2 2 0 NAD(P)H-binding FAD_binding_4 PF01565.23 KXL47432.1 - 3.6e-16 59.1 0.0 6.4e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain ADH_N PF08240.12 KXL47433.1 - 1.8e-26 92.1 1.6 3.7e-26 91.1 1.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXL47433.1 - 7.8e-20 71.2 0.6 1.4e-19 70.4 0.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXL47433.1 - 0.0018 19.4 0.0 0.0033 18.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2742 PF10888.8 KXL47433.1 - 0.18 12.1 0.1 0.73 10.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2742) MFS_1 PF07690.16 KXL47434.1 - 4.3e-29 101.5 29.4 4.3e-29 101.5 29.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL47434.1 - 2.3e-11 43.2 24.7 2.8e-10 39.7 24.7 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 KXL47434.1 - 9.2e-06 24.2 4.4 9.2e-06 24.2 4.4 1.6 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.13 KXL47434.1 - 0.007 14.8 3.1 0.01 14.3 3.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Rick_17kDa_Anti PF05433.15 KXL47434.1 - 0.37 10.7 7.9 0.68 9.8 0.2 2.6 2 0 0 2 2 2 0 Glycine zipper 2TM domain Pkinase PF00069.25 KXL47436.1 - 2.7e-26 92.5 0.0 3.4e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL47436.1 - 7.3e-14 51.7 0.0 1e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXL47436.1 - 4.5e-09 35.6 0.0 6.7e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXL47436.1 - 0.00018 21.5 0.0 0.0015 18.5 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family ATP-synt_J PF04911.12 KXL47437.1 - 3.4e-28 97.0 2.9 3.8e-28 96.8 2.9 1.0 1 0 0 1 1 1 1 ATP synthase j chain DASH_Spc19 PF08287.11 KXL47438.1 - 8.1e-44 149.3 1.2 1.2e-43 148.7 1.2 1.3 1 0 0 1 1 1 1 Spc19 MMM1 PF10296.9 KXL47439.1 - 0.0071 15.4 0.0 0.016 14.3 0.0 1.4 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 MATalpha_HMGbox PF04769.12 KXL47440.1 - 1.2e-31 109.6 0.0 1.5e-31 109.3 0.0 1.0 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box HMG_box PF00505.19 KXL47440.1 - 0.54 10.7 2.3 4.1 7.9 2.3 2.3 1 1 0 1 1 1 0 HMG (high mobility group) box ANAPC5 PF12862.7 KXL47441.1 - 8e-31 106.0 4.6 2.3e-30 104.5 3.2 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 Exo_endo_phos PF03372.23 KXL47442.1 - 1.8e-08 34.2 0.3 4.8e-08 32.8 0.3 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 KXL47442.1 - 0.00064 19.8 2.5 0.0015 18.5 2.5 1.7 1 0 0 1 1 1 1 GRF zinc finger Putative_PNPOx PF01243.20 KXL47443.1 - 9.7e-11 41.7 0.0 1.9e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Zn_clus PF00172.18 KXL47444.1 - 7.8e-05 22.7 8.2 0.00014 21.9 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4183 PF13799.6 KXL47444.1 - 0.2 11.5 0.3 0.39 10.6 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4183) SAICAR_synt PF01259.18 KXL47445.1 - 1.1e-99 333.1 0.0 1.3e-99 332.9 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase F-box-like PF12937.7 KXL47446.1 - 3.5e-07 30.0 3.5 3.5e-07 30.0 3.5 2.3 3 0 0 3 3 3 1 F-box-like COX6A PF02046.15 KXL47447.1 - 3.2e-51 172.5 0.5 3.6e-51 172.3 0.5 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Tannase PF07519.11 KXL47448.1 - 3.4e-110 369.2 0.9 4e-110 368.9 0.9 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KXL47448.1 - 0.001 18.4 0.0 0.036 13.3 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF1338 PF07063.13 KXL47448.1 - 0.23 10.6 0.0 0.34 10.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1338) EI24 PF07264.11 KXL47449.1 - 5.2e-12 46.4 4.4 2e-11 44.4 4.4 1.8 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DFP PF04127.15 KXL47450.1 - 6.1e-13 49.0 0.0 4.2e-05 23.5 0.0 3.3 2 1 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein zf-C3HC4 PF00097.25 KXL47452.1 - 0.019 14.8 2.6 0.051 13.4 2.7 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4407 PF14362.6 KXL47452.1 - 0.83 8.9 16.8 1.2 8.4 16.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PAP_RNA-bind PF04926.15 KXL47452.1 - 1.9 8.1 5.3 3.5 7.2 5.2 1.5 1 1 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain zf-RING_2 PF13639.6 KXL47452.1 - 1.9 8.9 6.5 3.9 7.9 6.5 1.5 1 0 0 1 1 1 0 Ring finger domain COesterase PF00135.28 KXL47453.1 - 1.3e-89 301.4 0.0 1.9e-89 300.9 0.0 1.2 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXL47453.1 - 0.0014 18.6 0.1 0.0041 17.0 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXL47453.1 - 0.13 11.7 0.1 0.24 10.8 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family ABC1 PF03109.16 KXL47454.1 - 3.1e-22 79.0 0.0 6.6e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 ABC1 family PGBA_C PF15437.6 KXL47454.1 - 0.041 14.3 0.1 0.11 12.8 0.1 1.8 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal APH PF01636.23 KXL47454.1 - 0.047 13.6 0.3 0.27 11.1 0.1 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family ABC_membrane PF00664.23 KXL47455.1 - 3.2e-21 76.2 6.7 2e-20 73.6 4.4 2.0 1 1 1 2 2 2 2 ABC transporter transmembrane region Fungal_trans_2 PF11951.8 KXL47456.1 - 1.6e-05 23.9 0.6 2.4e-05 23.4 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3328 PF11807.8 KXL47457.1 - 5.5e-48 163.6 1.0 6.2e-48 163.5 1.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 KXL47458.1 - 2.9e-45 154.7 0.6 3.5e-45 154.5 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 KXL47459.1 - 1.6e-38 132.7 0.5 1.9e-38 132.5 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) RPEL PF02755.15 KXL47460.1 - 1.4e-25 88.2 21.6 2.3e-09 36.6 1.3 3.8 5 0 0 5 5 5 3 RPEL repeat Rotamase_3 PF13616.6 KXL47460.1 - 0.017 15.7 2.0 0.35 11.4 0.1 2.1 1 1 1 2 2 2 0 PPIC-type PPIASE domain Bac_rhodopsin PF01036.18 KXL47461.1 - 1.6e-48 165.2 17.5 2e-48 164.9 17.5 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein MerC PF03203.14 KXL47461.1 - 0.08 13.4 13.2 0.23 11.9 6.1 2.4 2 0 0 2 2 2 0 MerC mercury resistance protein DUF1772 PF08592.11 KXL47461.1 - 0.25 11.6 13.1 0.42 10.9 1.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) DUF4381 PF14316.6 KXL47461.1 - 0.65 10.2 2.0 4.2 7.6 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) TMEM208_SND2 PF05620.11 KXL47461.1 - 0.95 9.2 9.2 0.5 10.1 2.4 2.8 2 1 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 DUF2516 PF10724.9 KXL47461.1 - 1.7 9.0 9.8 0.62 10.4 3.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) DUF3810 PF12725.7 KXL47461.1 - 1.9 7.7 6.6 9.4 5.5 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Phage_holin_3_6 PF07332.11 KXL47461.1 - 3.1 7.9 11.6 4.7 7.3 5.8 2.8 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4131 PF13567.6 KXL47461.1 - 4.2 7.0 7.9 0.66 9.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) STE PF02200.16 KXL47463.1 - 2.4e-56 188.9 0.1 3.7e-56 188.3 0.1 1.3 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 KXL47463.1 - 1.2e-09 38.1 14.2 6.1e-05 23.3 3.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXL47463.1 - 4.7e-08 33.1 4.9 4.7e-08 33.1 4.9 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXL47463.1 - 8.5e-05 23.1 18.4 0.0027 18.4 1.8 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXL47463.1 - 8.7e-05 22.4 1.5 8.7e-05 22.4 1.5 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 KXL47463.1 - 0.0038 17.6 4.1 0.007 16.7 1.9 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXL47463.1 - 0.0051 17.1 2.3 0.049 13.9 1.2 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding PhyH PF05721.13 KXL47465.1 - 6.9e-27 95.1 0.1 9.4e-27 94.6 0.1 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AtuA PF07287.11 KXL47466.1 - 8.8e-78 261.5 0.5 2e-40 138.6 0.1 2.0 1 1 1 2 2 2 2 Acyclic terpene utilisation family protein AtuA Fungal_trans PF04082.18 KXL47468.1 - 3.3e-18 65.7 0.3 6.6e-18 64.7 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pantoate_transf PF02548.15 KXL47469.1 - 8e-108 359.7 1.2 9.5e-108 359.5 1.2 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KXL47469.1 - 1.5e-06 27.9 0.4 1.5e-06 27.9 0.4 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF4861 PF16153.5 KXL47469.1 - 0.028 13.4 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4861) APG12 PF04110.13 KXL47470.1 - 3.3e-26 91.5 0.0 4.7e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 KXL47470.1 - 0.13 12.5 0.0 0.22 11.7 0.0 1.5 1 1 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like Dfp1_Him1_M PF08630.10 KXL47471.1 - 2.4e-40 137.7 0.0 7.8e-40 136.0 0.0 1.9 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.12 KXL47471.1 - 2.9e-22 78.5 0.3 5e-22 77.7 0.3 1.4 1 0 0 1 1 1 1 DBF zinc finger ACT PF01842.25 KXL47471.1 - 0.04 13.7 0.1 0.96 9.3 0.0 2.8 3 0 0 3 3 3 0 ACT domain DUF4817 PF16087.5 KXL47471.1 - 0.13 12.1 0.1 0.31 10.9 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) DUF4633 PF15464.6 KXL47471.1 - 4 7.6 6.6 0.56 10.4 0.1 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4633) Tannase PF07519.11 KXL47472.1 - 2.6e-78 264.0 1.7 1.4e-76 258.3 1.7 2.0 1 1 0 1 1 1 1 Tannase and feruloyl esterase Sugar_tr PF00083.24 KXL47473.1 - 2.5e-92 310.1 28.8 2.9e-92 309.9 28.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL47473.1 - 1.7e-16 60.1 49.8 3.7e-08 32.7 21.3 2.6 1 1 1 3 3 3 2 Major Facilitator Superfamily PQ-loop PF04193.14 KXL47476.1 - 1e-18 66.8 4.7 2.1e-12 46.6 0.0 2.7 3 0 0 3 3 3 2 PQ loop repeat Phage_tail_X PF05489.12 KXL47476.1 - 0.069 12.8 0.8 0.069 12.8 0.8 1.6 2 0 0 2 2 2 0 Phage Tail Protein X GGACT PF06094.12 KXL47477.1 - 8.8e-21 74.8 0.1 1.4e-20 74.1 0.1 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like EMP24_GP25L PF01105.24 KXL47478.1 - 1.5e-47 161.9 0.1 1.7e-47 161.7 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2271 PF10029.9 KXL47478.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2271) EthD PF07110.11 KXL47479.1 - 3.7e-17 63.2 0.7 4.7e-17 62.9 0.7 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KXL47479.1 - 1.2e-05 25.8 0.3 6.3e-05 23.4 0.3 1.9 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase Glyco_hydro_35 PF01301.19 KXL47480.1 - 2.8e-84 283.5 0.2 4.2e-84 282.9 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 KXL47480.1 - 5.8e-54 182.6 1.4 9.3e-54 182.0 1.4 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 KXL47480.1 - 1.5e-46 157.6 5.9 9.6e-26 90.6 0.2 2.8 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 KXL47480.1 - 5.2e-16 58.0 0.0 1.3e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 DUF3449 PF11931.8 KXL47481.1 - 2.5e-75 252.3 0.3 2.5e-75 252.3 0.3 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 KXL47481.1 - 3.4e-26 91.6 0.7 3.4e-26 91.6 0.7 1.9 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 KXL47481.1 - 6.4e-16 57.9 0.5 2e-15 56.3 0.5 1.9 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 KXL47481.1 - 1.3e-08 34.9 2.8 6.1e-07 29.6 1.1 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXL47481.1 - 7.9e-08 32.4 4.8 3.4e-07 30.4 1.8 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KXL47481.1 - 0.00022 21.5 0.2 0.013 15.8 0.1 2.8 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KXL47481.1 - 0.032 15.1 1.1 9.9 7.3 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KXL47481.1 - 0.26 11.8 4.2 2.8 8.6 0.5 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type PRP9_N PF16958.5 KXL47481.1 - 1.3 9.0 20.0 0.43 10.6 0.5 3.7 3 1 1 4 4 4 0 Pre-mRNA-splicing factor PRP9 N-terminus DEAD PF00270.29 KXL47482.1 - 2e-41 141.7 0.1 3.4e-41 140.9 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXL47482.1 - 1.2e-32 112.5 0.0 6.3e-32 110.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 KXL47482.1 - 0.00038 20.2 0.0 0.00056 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXL47482.1 - 0.00082 19.7 0.0 0.0078 16.6 0.1 2.2 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KXL47482.1 - 0.0025 17.9 0.0 0.0049 16.9 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 KXL47482.1 - 0.034 14.1 0.1 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 Flavivirus DEAD domain Helicase_RecD PF05127.14 KXL47482.1 - 0.036 13.9 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 Helicase TniB PF05621.11 KXL47482.1 - 0.086 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 KXL47482.1 - 0.13 12.6 0.4 0.39 11.0 0.4 1.8 1 1 0 1 1 1 0 AAA domain Tmemb_cc2 PF10267.9 KXL47483.1 - 7.3e-06 25.4 0.8 9.8e-06 25.0 0.8 1.1 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Sipho_Gp157 PF05565.11 KXL47483.1 - 0.0014 18.7 1.9 0.0021 18.1 1.9 1.2 1 0 0 1 1 1 1 Siphovirus Gp157 CdvA PF18822.1 KXL47483.1 - 0.0071 16.2 8.9 0.011 15.6 8.9 1.2 1 0 0 1 1 1 1 CdvA-like coiled-coil domain Prefoldin_2 PF01920.20 KXL47483.1 - 0.012 15.5 5.1 0.012 15.5 5.1 2.7 2 1 1 3 3 2 0 Prefoldin subunit Med8 PF10232.9 KXL47483.1 - 0.013 15.1 3.1 0.022 14.4 3.1 1.3 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 FAM184 PF15665.5 KXL47483.1 - 0.023 14.5 12.0 0.038 13.8 12.0 1.3 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B VSG_B PF13206.6 KXL47483.1 - 0.024 13.9 0.3 0.032 13.5 0.3 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain SKA2 PF16740.5 KXL47483.1 - 0.035 13.9 5.4 0.068 13.0 5.4 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Exonuc_VII_L PF02601.15 KXL47483.1 - 0.04 13.5 2.0 0.062 12.9 2.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Herpes_UL6 PF01763.16 KXL47483.1 - 0.052 12.1 2.6 0.068 11.7 2.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Baculo_PEP_C PF04513.12 KXL47483.1 - 0.084 12.9 0.9 0.13 12.3 0.9 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus bZIP_1 PF00170.21 KXL47483.1 - 0.097 12.8 19.7 0.083 13.0 10.3 2.6 1 1 1 2 2 2 0 bZIP transcription factor DUF5344 PF17279.2 KXL47483.1 - 0.11 13.0 2.7 0.14 12.8 1.8 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5344) Jnk-SapK_ap_N PF09744.9 KXL47483.1 - 0.12 12.6 12.4 0.25 11.6 12.4 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Golgin_A5 PF09787.9 KXL47483.1 - 0.12 11.8 9.6 0.2 11.1 9.6 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Seryl_tRNA_N PF02403.22 KXL47483.1 - 0.21 11.8 11.6 0.36 11.1 11.6 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain FapA PF03961.13 KXL47483.1 - 0.23 10.0 2.2 0.3 9.6 2.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A UPF0242 PF06785.11 KXL47483.1 - 0.23 11.5 6.5 0.44 10.6 6.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TRAF_BIRC3_bd PF16673.5 KXL47483.1 - 0.3 10.9 5.4 0.59 10.0 5.4 1.4 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain bZIP_2 PF07716.15 KXL47483.1 - 0.36 11.0 24.8 0.071 13.2 14.2 2.5 1 1 1 2 2 2 0 Basic region leucine zipper Fungal_TACC PF12709.7 KXL47483.1 - 0.45 11.0 5.3 0.72 10.3 4.8 1.6 1 1 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF4107 PF13389.6 KXL47483.1 - 0.65 10.1 0.0 0.65 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4107) Cep57_CLD PF14073.6 KXL47483.1 - 1.1 9.2 14.5 0.042 13.9 8.7 1.6 2 0 0 2 2 1 0 Centrosome localisation domain of Cep57 DUF4446 PF14584.6 KXL47483.1 - 2.8 7.9 4.0 4.4 7.3 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) TMPIT PF07851.13 KXL47483.1 - 3 7.0 5.7 4.1 6.5 5.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein AAA_13 PF13166.6 KXL47483.1 - 3.7 6.1 7.7 6.6 5.3 7.7 1.3 1 1 0 1 1 1 0 AAA domain bZIP_Maf PF03131.17 KXL47483.1 - 4.6 7.8 25.1 0.27 11.8 17.4 2.5 2 1 0 2 2 1 0 bZIP Maf transcription factor PIEZO PF15917.5 KXL47483.1 - 5.7 6.3 11.0 0.43 10.0 4.2 2.0 2 0 0 2 2 2 0 Piezo Fzo_mitofusin PF04799.13 KXL47483.1 - 6.6 6.2 8.1 10 5.6 8.1 1.2 1 0 0 1 1 1 0 fzo-like conserved region Allexi_40kDa PF05549.11 KXL47483.1 - 8.3 5.8 7.0 0.28 10.6 0.5 1.7 2 0 0 2 2 2 0 Allexivirus 40kDa protein MCM PF00493.23 KXL47484.1 - 2.8e-104 347.1 0.0 5.3e-104 346.2 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KXL47484.1 - 9.3e-34 116.0 0.0 1.8e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KXL47484.1 - 6.4e-28 97.0 1.2 1.5e-27 95.8 1.2 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KXL47484.1 - 5.5e-14 52.6 0.5 1.2e-13 51.6 0.5 1.5 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KXL47484.1 - 1.7e-06 27.6 0.0 0.00018 21.0 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KXL47484.1 - 8.9e-06 25.7 0.0 2e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KXL47484.1 - 0.00061 19.7 0.1 0.0024 17.7 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KXL47484.1 - 0.035 13.8 0.1 0.63 9.7 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Ogr_Delta PF04606.12 KXL47484.1 - 0.11 12.5 0.5 0.27 11.2 0.5 1.6 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger Mg_chelatase_C PF13335.6 KXL47484.1 - 5 7.8 8.1 55 4.5 5.4 3.5 3 1 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal NMO PF03060.15 KXL47487.1 - 6.1e-57 193.5 0.2 2.3e-56 191.6 0.2 1.7 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KXL47487.1 - 5.7e-13 48.6 0.1 3.8e-12 45.9 0.1 1.9 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KXL47487.1 - 0.0014 17.7 0.1 0.0027 16.8 0.1 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KXL47487.1 - 0.044 12.9 0.4 0.24 10.5 0.4 2.1 1 1 0 1 1 1 0 Conserved region in glutamate synthase DUF1729 PF08354.10 KXL47487.1 - 0.057 12.3 0.0 0.11 11.4 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1729) His_biosynth PF00977.21 KXL47487.1 - 0.081 12.4 0.1 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein HAT_KAT11 PF08214.11 KXL47488.1 - 9.3e-78 261.9 0.0 1.3e-77 261.5 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein Ribonucleas_3_3 PF14622.6 KXL47489.1 - 5.1e-27 94.6 0.0 7.7e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KXL47489.1 - 2.8e-06 27.9 0.0 4.5e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease III domain HSBP1 PF06825.12 KXL47489.1 - 0.2 11.5 0.0 18 5.3 0.0 2.3 2 0 0 2 2 2 0 Heat shock factor binding protein 1 FLILHELTA PF10306.9 KXL47490.1 - 6.4e-31 106.6 1.1 1.3e-30 105.6 0.1 2.0 2 0 0 2 2 2 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 KXL47490.1 - 0.0023 18.5 0.3 0.0039 17.7 0.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) Dynamin_M PF01031.20 KXL47491.1 - 5.8e-102 340.7 0.4 9.6e-102 340.0 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KXL47491.1 - 2.8e-56 190.2 0.0 5.3e-56 189.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KXL47491.1 - 1.2e-29 102.3 6.3 2.5e-29 101.2 6.3 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KXL47491.1 - 1.8e-05 24.8 0.2 9.7e-05 22.4 0.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 KXL47491.1 - 0.018 14.8 0.6 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain ATP-synt_ab PF00006.25 KXL47492.1 - 1.4e-107 358.2 0.1 2.9e-107 357.1 0.0 1.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KXL47492.1 - 5.8e-46 155.3 0.0 1.3e-45 154.2 0.0 1.6 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 KXL47492.1 - 3.2e-15 56.4 0.6 6.5e-15 55.4 0.6 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 KXL47492.1 - 0.09 12.0 0.1 1.3 8.1 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain DUF1295 PF06966.12 KXL47493.1 - 1.3e-15 57.5 0.5 1.7e-15 57.2 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 KXL47493.1 - 1e-05 25.6 2.5 1.4e-05 25.1 2.5 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ERG4_ERG24 PF01222.17 KXL47493.1 - 0.00014 20.8 7.9 0.00036 19.4 6.2 2.2 2 1 0 2 2 2 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.13 KXL47493.1 - 0.001 19.4 1.1 0.0024 18.3 1.1 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.14 KXL47493.1 - 0.048 14.1 0.0 0.12 12.8 0.0 1.6 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family polyprenyl_synt PF00348.17 KXL47494.1 - 4.5e-95 317.6 0.1 6.3e-95 317.1 0.1 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase RNase_H2-Ydr279 PF09468.10 KXL47494.1 - 0.00029 21.0 2.3 0.0026 18.0 1.0 2.2 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain YkyB PF14177.6 KXL47494.1 - 0.05 13.9 0.0 0.085 13.1 0.0 1.4 1 0 0 1 1 1 0 YkyB-like protein DIT1_PvcA PF05141.12 KXL47494.1 - 0.092 12.2 1.0 0.13 11.7 1.0 1.2 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein ANAPC8 PF04049.13 KXL47495.1 - 8.9e-49 165.1 0.1 1.7e-47 161.0 0.0 2.3 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 KXL47495.1 - 3.1e-19 67.9 16.3 0.00045 19.9 0.0 6.3 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KXL47495.1 - 9.4e-19 66.0 26.1 0.0014 18.5 1.3 8.0 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 KXL47495.1 - 5.8e-14 51.1 10.0 4.5e-05 23.3 0.0 6.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXL47495.1 - 1.6e-12 47.1 29.3 0.0035 18.0 0.8 8.3 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 KXL47495.1 - 6.7e-12 44.9 6.4 4.5e-05 23.0 0.5 4.6 3 1 1 4 4 4 3 TPR repeat TPR_16 PF13432.6 KXL47495.1 - 1.3e-10 41.8 23.4 3.7e-05 24.3 0.2 6.3 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXL47495.1 - 1.4e-07 31.9 13.3 0.0089 16.5 0.2 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXL47495.1 - 9.9e-06 25.6 4.9 0.085 13.3 0.4 5.5 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXL47495.1 - 0.00025 20.9 21.7 0.49 10.5 0.2 6.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 KXL47495.1 - 0.00031 21.2 20.5 0.98 10.2 0.0 7.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 KXL47495.1 - 0.0025 17.1 7.7 0.092 11.9 4.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXL47495.1 - 0.0042 17.3 25.6 2.3 8.6 0.1 6.5 4 1 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXL47495.1 - 0.0091 16.1 24.8 0.022 14.9 0.0 6.3 5 2 2 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXL47495.1 - 0.034 14.4 12.9 1.2 9.4 1.2 5.8 5 1 2 7 7 6 0 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 KXL47495.1 - 0.14 11.1 0.1 32 3.4 0.0 3.0 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) PPR PF01535.20 KXL47495.1 - 0.25 11.7 1.0 67 4.1 0.0 3.8 4 0 0 4 4 3 0 PPR repeat DUF4530 PF15039.6 KXL47495.1 - 0.28 11.3 4.8 0.89 9.7 4.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) Ribosomal_60s PF00428.19 KXL47495.1 - 3.5 8.3 8.7 8.6 7.0 8.7 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein TPR_10 PF13374.6 KXL47495.1 - 5.9 6.9 17.9 53 3.9 0.1 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat ABC_tran PF00005.27 KXL47496.1 - 6.9e-43 146.5 0.0 1.2e-22 80.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXL47496.1 - 6.3e-29 101.5 30.7 1.8e-26 93.4 11.7 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.6 KXL47496.1 - 6.9e-11 42.5 4.3 0.13 12.1 0.0 4.4 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXL47496.1 - 1.3e-05 24.7 0.6 3.5 7.0 0.0 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KXL47496.1 - 3.5e-05 24.3 0.0 0.65 10.4 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KXL47496.1 - 0.00014 22.1 0.0 1.2 9.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KXL47496.1 - 0.00018 21.1 0.4 0.59 9.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXL47496.1 - 0.00035 20.5 0.0 1.1 9.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase T2SSE PF00437.20 KXL47496.1 - 0.0042 16.2 0.0 0.67 9.0 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein MMR_HSR1 PF01926.23 KXL47496.1 - 0.0051 16.9 0.4 2.9 8.0 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase TerC PF03741.16 KXL47496.1 - 0.0066 16.1 0.3 0.0066 16.1 0.3 3.4 3 0 0 3 3 3 1 Integral membrane protein TerC family FtsK_SpoIIIE PF01580.18 KXL47496.1 - 0.01 15.2 0.2 3.5 6.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.9 KXL47496.1 - 0.019 13.9 0.0 5.2 5.9 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 KXL47496.1 - 0.019 15.1 0.9 2 8.5 0.2 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_7 PF12775.7 KXL47496.1 - 0.021 14.3 0.0 5.4 6.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_23 PF13476.6 KXL47496.1 - 0.029 14.9 1.3 2.9 8.3 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KXL47496.1 - 0.034 14.3 0.0 8.7 6.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KXL47496.1 - 0.041 14.4 0.0 16 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KXL47496.1 - 0.059 13.1 0.0 1.6 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 KXL47496.1 - 0.12 12.6 0.1 9.6 6.5 0.0 3.1 2 1 1 3 3 3 0 Putative exonuclease SbcCD, C subunit MobB PF03205.14 KXL47496.1 - 0.13 12.1 0.1 2.6 7.9 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 KXL47496.1 - 0.13 12.1 0.0 6.3 6.7 0.0 2.5 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.22 KXL47496.1 - 0.14 11.3 0.2 13 4.9 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_15 PF13175.6 KXL47496.1 - 0.15 11.8 0.2 16 5.1 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain ATPase_2 PF01637.18 KXL47496.1 - 0.16 11.8 0.0 8.5 6.2 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Roc PF08477.13 KXL47496.1 - 0.18 12.0 0.4 9.8 6.4 0.0 2.9 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KXL47496.1 - 0.18 11.5 0.1 12 5.6 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein HET PF06985.11 KXL47497.1 - 4.6e-11 43.3 9.9 1.1e-08 35.6 1.7 2.6 1 1 0 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF4401 PF14351.6 KXL47498.1 - 0.0012 18.2 0.5 0.0013 18.1 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) AA_permease_2 PF13520.6 KXL47498.1 - 0.008 15.1 2.5 0.008 15.1 2.5 1.5 2 0 0 2 2 2 1 Amino acid permease DUF5367 PF17329.2 KXL47498.1 - 0.019 15.1 0.1 0.043 13.9 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5367) DUF4181 PF13789.6 KXL47498.1 - 0.038 14.2 1.2 0.064 13.5 0.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4181) DUF5134 PF17197.4 KXL47498.1 - 0.042 13.7 2.5 0.06 13.3 2.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5134) DUF2070 PF09843.9 KXL47498.1 - 0.052 11.8 0.3 0.066 11.5 0.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF1516 PF07457.11 KXL47498.1 - 0.062 13.5 3.0 0.11 12.7 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1516) Ni_hydr_CYTB PF01292.20 KXL47498.1 - 0.098 12.2 5.7 0.23 11.0 5.9 1.5 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 Prominin PF05478.11 KXL47498.1 - 0.22 9.5 0.1 0.29 9.0 0.1 1.1 1 0 0 1 1 1 0 Prominin DUF4079 PF13301.6 KXL47498.1 - 0.3 11.2 2.9 1.3 9.2 3.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) FtsK_4TM PF13491.6 KXL47498.1 - 0.33 10.6 6.3 0.13 12.0 3.5 1.8 2 1 0 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE Virul_fac_BrkB PF03631.15 KXL47498.1 - 0.85 9.2 9.1 10 5.6 8.5 2.3 2 1 1 3 3 3 0 Virulence factor BrkB DLH PF01738.18 KXL47499.1 - 3.3e-18 66.0 0.0 6.8e-18 65.0 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Fungal_trans PF04082.18 KXL47500.1 - 1.3e-14 53.8 0.0 2.6e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL47500.1 - 4.8e-09 36.2 10.9 8.3e-09 35.4 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2778 PF10908.8 KXL47500.1 - 0.028 14.7 0.5 0.26 11.6 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2778) NuA4 PF09340.10 KXL47500.1 - 0.069 13.0 0.2 0.21 11.5 0.2 1.8 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 DUF3277 PF11681.8 KXL47502.1 - 0.066 13.1 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) Sulfate_transp PF00916.20 KXL47504.1 - 1.7e-100 336.5 19.6 2.2e-100 336.1 19.6 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KXL47504.1 - 3.3e-07 30.0 0.0 6.9e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KXL47504.1 - 0.099 13.0 0.2 0.29 11.5 0.2 1.7 1 0 0 1 1 1 0 STAS domain zf-CHCC PF10276.9 KXL47505.1 - 1.1e-14 54.2 2.8 1.9e-14 53.4 2.8 1.4 1 0 0 1 1 1 1 Zinc-finger domain UPF0047 PF01894.17 KXL47506.1 - 1.1e-37 128.7 0.0 1.3e-37 128.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 GMC_oxred_C PF05199.13 KXL47508.1 - 4.3e-29 101.9 0.0 3.2e-28 99.0 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KXL47508.1 - 4.1e-23 82.2 0.0 1.7e-16 60.5 0.0 3.1 3 0 0 3 3 3 3 GMC oxidoreductase Pyr_redox_2 PF07992.14 KXL47508.1 - 0.00013 21.3 0.0 0.0002 20.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXL47508.1 - 0.0014 18.8 0.0 0.0039 17.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KXL47508.1 - 0.021 14.1 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain AAA_31 PF13614.6 KXL47508.1 - 0.044 13.7 0.2 0.23 11.3 0.0 2.1 1 1 1 2 2 2 0 AAA domain Lycopene_cycl PF05834.12 KXL47508.1 - 0.048 12.7 0.0 0.072 12.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 KXL47508.1 - 0.054 12.2 0.0 0.46 9.1 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 KXL47508.1 - 0.059 12.6 0.0 7.7 5.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXL47508.1 - 0.067 12.3 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain SUIM_assoc PF16619.5 KXL47509.1 - 0.11 12.6 5.0 0.16 12.1 5.0 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Vps54 PF07928.12 KXL47510.1 - 3.1e-45 153.9 0.0 7.1e-45 152.7 0.0 1.7 1 0 0 1 1 1 1 Vps54-like protein Vps54_N PF10475.9 KXL47510.1 - 8.5e-08 31.8 0.2 3e-07 30.0 0.2 1.9 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Cytochrom_C550 PF14495.6 KXL47510.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Cytochrome c-550 domain FliJ PF02050.16 KXL47510.1 - 0.21 11.8 8.6 0.14 12.3 0.7 3.5 3 0 0 3 3 3 0 Flagellar FliJ protein COG2 PF06148.11 KXL47510.1 - 0.24 11.5 1.0 0.8 9.8 1.0 1.9 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2722 PF10846.8 KXL47511.1 - 0.01 14.8 0.4 0.013 14.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) PhoLip_ATPase_C PF16212.5 KXL47511.1 - 0.036 13.8 4.8 0.083 12.6 4.8 1.5 1 0 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal SUIM_assoc PF16619.5 KXL47511.1 - 0.054 13.6 6.0 0.1 12.7 6.0 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 KXL47511.1 - 0.5 9.9 9.8 0.73 9.4 9.8 1.1 1 0 0 1 1 1 0 Spt20 family SdpI PF13630.6 KXL47511.1 - 3.6 7.8 13.1 0.31 11.2 3.1 2.8 2 0 0 2 2 2 0 SdpI/YhfL protein family UEV PF05743.13 KXL47512.1 - 3e-37 127.2 0.0 4.1e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 UEV domain UQ_con PF00179.26 KXL47512.1 - 0.00097 18.8 0.0 0.0013 18.3 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KXL47512.1 - 0.033 14.5 0.1 0.039 14.2 0.1 1.4 1 1 0 1 1 1 0 RWD domain EXS PF03124.14 KXL47513.1 - 0.0012 18.3 0.1 0.0013 18.1 0.1 1.0 1 0 0 1 1 1 1 EXS family Fe-ADH PF00465.19 KXL47514.1 - 3.2e-71 240.1 0.0 3.9e-71 239.8 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KXL47514.1 - 0.00024 20.9 0.0 0.026 14.2 0.0 2.4 2 1 0 2 2 2 2 Iron-containing alcohol dehydrogenase Spermine_synth PF01564.17 KXL47514.1 - 0.14 11.5 0.0 0.34 10.3 0.0 1.6 1 0 0 1 1 1 0 Spermine/spermidine synthase domain FAD_binding_3 PF01494.19 KXL47515.1 - 3.4e-26 92.3 0.0 4.5e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 KXL47515.1 - 1.5e-05 24.2 0.0 0.00024 20.2 0.0 2.1 1 1 0 1 1 1 1 Squalene epoxidase Pyr_redox_3 PF13738.6 KXL47515.1 - 0.00098 18.5 0.1 0.056 12.7 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXL47515.1 - 0.0042 17.3 0.0 0.0088 16.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXL47515.1 - 0.014 16.0 0.1 0.047 14.3 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXL47515.1 - 0.02 14.1 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXL47515.1 - 0.021 14.4 1.2 0.062 12.9 0.1 2.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.22 KXL47515.1 - 0.11 11.5 0.3 2.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Adap_comp_sub PF00928.21 KXL47516.1 - 6.2e-56 189.7 0.0 7.9e-56 189.3 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KXL47516.1 - 0.042 13.8 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 Clathrin adaptor complex small chain DEAD PF00270.29 KXL47518.1 - 7e-50 169.2 0.0 2.6e-48 164.1 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXL47518.1 - 6.8e-23 81.1 0.0 5.8e-22 78.1 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KXL47518.1 - 6.5e-19 67.9 0.1 1.3e-18 67.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KXL47518.1 - 0.00028 20.9 0.0 0.0012 18.9 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KXL47518.1 - 0.046 14.0 0.5 0.81 10.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain EMP24_GP25L PF01105.24 KXL47519.1 - 5.3e-43 147.1 0.0 6.4e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD N_BRCA1_IG PF16158.5 KXL47520.1 - 3e-32 111.4 0.0 7.6e-32 110.1 0.0 1.7 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 KXL47520.1 - 7e-22 77.0 54.3 1.3e-07 31.3 8.2 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type C1_2 PF03107.16 KXL47520.1 - 0.005 17.1 7.4 0.005 17.1 7.4 4.6 4 0 0 4 4 4 2 C1 domain HSD3 PF15244.6 KXL47520.1 - 0.13 11.8 5.3 0.24 10.9 5.3 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 Btz PF09405.10 KXL47521.1 - 9.2e-21 74.5 5.1 9.2e-21 74.5 5.1 2.1 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding Aldedh PF00171.22 KXL47522.1 - 1.2e-106 357.0 1.6 1.6e-106 356.6 1.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family zf-U1 PF06220.12 KXL47523.1 - 9.4e-22 76.5 3.0 1.2e-21 76.1 3.0 1.2 1 0 0 1 1 1 1 U1 zinc finger Actin_micro PF17003.5 KXL47523.1 - 0.25 10.5 0.1 0.3 10.2 0.1 1.0 1 0 0 1 1 1 0 Putative actin-like family Ribosomal_L22 PF00237.19 KXL47525.1 - 1.5e-26 92.6 0.1 5e-26 90.9 0.1 1.9 1 1 0 1 1 1 1 Ribosomal protein L22p/L17e Calsequestrin PF01216.17 KXL47525.1 - 0.18 10.8 0.1 0.27 10.2 0.1 1.2 1 0 0 1 1 1 0 Calsequestrin RRM_1 PF00076.22 KXL47526.1 - 4e-46 154.7 2.9 1.3e-13 50.5 0.2 4.9 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXL47526.1 - 3.9e-22 77.9 0.4 2.4e-14 52.9 0.0 3.7 3 1 0 3 3 3 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KXL47526.1 - 1.4e-07 31.4 0.0 2.7 8.1 0.0 4.4 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KXL47526.1 - 3.3e-05 23.8 0.5 0.77 9.8 0.1 4.5 4 0 0 4 4 4 1 RNA binding motif Lsm_interact PF05391.11 KXL47526.1 - 0.013 14.9 0.1 0.038 13.5 0.1 1.9 1 0 0 1 1 1 0 Lsm interaction motif BSD PF03909.17 KXL47526.1 - 0.033 14.2 0.5 0.12 12.4 0.5 2.0 1 0 0 1 1 1 0 BSD domain Anti-adapt_IraP PF10796.9 KXL47526.1 - 0.055 14.0 0.0 0.17 12.5 0.0 1.8 1 0 0 1 1 1 0 Sigma-S stabilisation anti-adaptor protein TPR_14 PF13428.6 KXL47526.1 - 3.5 8.7 9.3 1.1e+02 4.0 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Lipase_GDSL_2 PF13472.6 KXL47527.1 - 1.3e-19 71.3 0.7 2e-19 70.6 0.7 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXL47527.1 - 8.9e-14 51.9 0.0 1.1e-13 51.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KXL47527.1 - 4.3e-06 27.0 0.0 6.4e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family ODV-E18 PF10717.9 KXL47527.1 - 0.037 13.9 1.4 3.9 7.4 0.0 3.3 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 ZF-HD_dimer PF04770.12 KXL47528.1 - 0.074 13.4 1.9 0.15 12.4 1.9 1.5 1 0 0 1 1 1 0 ZF-HD protein dimerisation region PhyH PF05721.13 KXL47530.1 - 1.1e-18 68.3 0.0 1.4e-18 67.9 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KXL47530.1 - 0.0098 16.3 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Sugar_tr PF00083.24 KXL47531.1 - 1.7e-80 271.2 18.0 1.9e-80 270.9 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL47531.1 - 1.8e-15 56.8 27.2 1.8e-15 56.8 27.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily EBP PF05241.12 KXL47531.1 - 0.0064 16.0 0.8 0.0064 16.0 0.8 2.2 2 1 0 2 2 2 1 Emopamil binding protein MIT PF04212.18 KXL47531.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain FHA PF00498.26 KXL47532.1 - 5.6e-14 52.3 0.0 1.2e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 FHA domain RNA_pol_Rpb1_1 PF04997.12 KXL47533.1 - 3e-80 269.9 0.0 4.8e-80 269.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KXL47533.1 - 1.7e-78 263.7 0.2 2.7e-78 263.1 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KXL47533.1 - 1.3e-71 240.2 0.0 2.1e-71 239.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KXL47533.1 - 1.6e-32 112.6 0.0 3.9e-32 111.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KXL47533.1 - 8.6e-29 99.7 0.2 3.1e-28 97.8 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 ICL PF00463.21 KXL47534.1 - 1.3e-295 980.9 1.7 1.5e-295 980.7 1.7 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KXL47534.1 - 2.7e-11 43.4 0.1 9.7e-11 41.6 0.0 1.9 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Abhydrolase_6 PF12697.7 KXL47535.1 - 0.00054 20.6 0.0 0.0016 19.1 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.15 KXL47535.1 - 0.0064 15.7 0.0 0.027 13.7 0.0 1.9 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 KXL47535.1 - 0.013 14.7 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF676 PF05057.14 KXL47535.1 - 0.047 13.2 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Peptidase_S9 PF00326.21 KXL47535.1 - 0.096 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KXL47535.1 - 0.098 12.3 0.7 0.66 9.6 0.0 2.6 3 0 0 3 3 3 0 alpha/beta hydrolase fold His_Phos_1 PF00300.22 KXL47537.1 - 1.5e-08 34.6 0.0 4.2e-08 33.1 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SBDS_C PF09377.10 KXL47538.1 - 5.1e-47 158.7 0.0 6.2e-47 158.4 0.0 1.1 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 KXL47538.1 - 0.026 14.6 0.1 0.052 13.6 0.1 1.5 1 0 0 1 1 1 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein GP38 PF05268.11 KXL47538.1 - 0.073 12.7 2.6 0.098 12.3 2.6 1.1 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 ANAPC4_WD40 PF12894.7 KXL47539.1 - 7.9e-06 26.1 0.0 3.2 8.1 0.0 4.5 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 KXL47539.1 - 0.05 11.6 0.1 0.34 8.8 0.0 2.3 1 1 1 3 3 3 0 IKI3 family PD40 PF07676.12 KXL47539.1 - 0.07 13.1 0.1 4.1 7.5 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat WD40 PF00400.32 KXL47539.1 - 0.11 13.4 3.9 5.7 8.0 0.1 4.7 5 0 0 5 5 5 0 WD domain, G-beta repeat HSP20 PF00011.21 KXL47540.1 - 7.5e-13 48.5 0.1 1e-12 48.1 0.1 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KXL47540.1 - 0.0081 15.7 0.0 0.038 13.6 0.0 2.0 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Fungal_trans PF04082.18 KXL47541.1 - 2.8e-22 79.0 0.1 6e-22 77.9 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL47541.1 - 1.7e-07 31.2 8.7 2.9e-07 30.5 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gag_MA PF01140.19 KXL47541.1 - 0.11 12.2 0.2 0.49 10.1 0.0 2.1 2 0 0 2 2 2 0 Matrix protein (MA), p15 Mannosidase_ig PF17786.1 KXL47542.1 - 1.9e-18 66.9 0.0 4.6e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KXL47542.1 - 2e-10 41.3 0.1 5.7e-10 39.8 0.1 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Fungal_trans PF04082.18 KXL47543.1 - 2.3e-17 62.9 0.7 2.3e-17 62.9 0.7 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL47543.1 - 6.5e-05 23.0 15.5 0.00014 21.9 15.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 KXL47544.1 - 5.6e-68 229.8 0.0 7.1e-68 229.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Oxysterol_BP PF01237.18 KXL47545.1 - 6.4e-132 439.9 0.0 2.3e-131 438.1 0.0 1.9 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.7 KXL47545.1 - 2e-14 53.9 0.1 5.8e-09 36.4 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXL47545.1 - 6.2e-12 45.4 0.1 0.00032 21.0 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat PH PF00169.29 KXL47545.1 - 9e-12 45.4 0.2 2.9e-11 43.8 0.2 1.9 1 0 0 1 1 1 1 PH domain Ank_5 PF13857.6 KXL47545.1 - 4.4e-11 42.8 0.3 4.9e-05 23.5 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXL47545.1 - 7.9e-11 42.3 0.0 1.7e-05 25.2 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXL47545.1 - 2e-09 36.9 0.0 0.0014 19.0 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat PH_8 PF15409.6 KXL47545.1 - 9.4e-06 25.8 0.2 2.4e-05 24.5 0.2 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KXL47545.1 - 4.8e-05 23.7 0.9 0.0002 21.7 0.9 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain adh_short_C2 PF13561.6 KXL47548.1 - 6.4e-67 225.5 2.0 7.5e-67 225.3 2.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL47548.1 - 9.2e-53 178.6 1.4 1.2e-52 178.2 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL47548.1 - 1.6e-16 60.8 1.2 2e-16 60.4 1.2 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KXL47548.1 - 0.0015 18.0 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 KXL47548.1 - 0.0073 16.2 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KXL47548.1 - 0.0089 15.2 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KXL47548.1 - 0.018 14.5 0.1 0.025 14.1 0.1 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 KXL47548.1 - 0.025 14.6 0.1 0.073 13.1 0.1 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KXL47548.1 - 0.03 13.7 0.5 0.25 10.7 0.1 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AIM3 PF17096.5 KXL47549.1 - 0.00086 20.2 1.6 0.00086 20.2 1.6 4.0 4 0 0 4 4 4 1 Altered inheritance of mitochondria protein 3 MIF PF01187.18 KXL47551.1 - 3.4e-14 53.1 0.0 6.4e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) BCNT PF07572.12 KXL47552.1 - 7.3e-19 67.6 3.4 1.2e-18 67.0 1.6 2.4 2 0 0 2 2 2 1 Bucentaur or craniofacial development eIF-3_zeta PF05091.12 KXL47552.1 - 0.41 9.6 6.0 0.59 9.0 6.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TSP_NTD PF17804.1 KXL47552.1 - 2.2 8.5 8.4 1.9 8.7 6.6 1.8 2 0 0 2 2 2 0 Tail specific protease N-terminal domain bZIP_1 PF00170.21 KXL47554.1 - 1.1e-08 35.1 10.5 4.1e-08 33.2 10.5 2.0 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KXL47554.1 - 0.00045 20.7 8.9 0.00045 20.7 8.9 3.5 3 0 0 3 3 3 1 bZIP Maf transcription factor bZIP_2 PF07716.15 KXL47554.1 - 0.015 15.3 13.0 0.015 15.3 13.0 3.1 3 0 0 3 3 3 0 Basic region leucine zipper RRM_1 PF00076.22 KXL47557.1 - 5e-44 148.0 1.4 1.2e-20 73.1 0.1 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 KXL47557.1 - 1.2e-18 68.0 0.1 1.7e-17 64.3 0.1 2.9 1 1 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.11 KXL47557.1 - 6.2e-05 23.0 3.6 0.0053 16.8 0.0 3.8 4 0 0 4 4 4 1 RNA binding motif Nup35_RRM_2 PF14605.6 KXL47557.1 - 0.0062 16.5 0.0 0.12 12.4 0.0 2.8 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KXL47557.1 - 0.033 14.0 0.0 2.4 8.1 0.0 2.7 3 0 0 3 3 3 0 Occluded RNA-recognition motif RRM_7 PF16367.5 KXL47557.1 - 0.038 14.1 0.1 0.59 10.3 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif Lactamase_B_4 PF13691.6 KXL47558.1 - 1.8e-24 85.2 0.1 5.6e-24 83.6 0.1 1.9 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 KXL47558.1 - 2e-13 50.3 0.5 8.2e-06 25.5 0.0 2.6 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Ribosomal_S7 PF00177.21 KXL47559.1 - 2.5e-36 124.6 1.6 3.3e-36 124.2 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e p450 PF00067.22 KXL47560.1 - 1.5e-72 244.8 0.0 1.9e-72 244.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 KXL47561.1 - 1e-14 54.6 0.2 6.4e-14 52.0 0.2 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXL47561.1 - 4.4e-09 36.0 0.0 0.00028 20.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXL47561.1 - 1.3e-06 27.8 0.7 3.1e-06 26.5 0.4 1.7 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KXL47561.1 - 4.7e-06 26.4 0.0 0.00098 18.8 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KXL47561.1 - 3.7e-05 22.6 0.1 0.001 17.9 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KXL47561.1 - 0.00012 21.5 0.2 0.00026 20.5 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXL47561.1 - 0.00033 20.8 0.5 0.00081 19.6 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KXL47561.1 - 0.0013 17.9 0.1 0.0019 17.4 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KXL47561.1 - 0.0019 17.5 0.1 0.0042 16.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXL47561.1 - 0.0019 18.7 0.4 1.2 9.8 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXL47561.1 - 0.0056 15.6 0.9 0.062 12.1 0.1 2.1 1 1 1 2 2 2 1 Tryptophan halogenase Thi4 PF01946.17 KXL47561.1 - 0.029 13.6 0.1 0.059 12.6 0.1 1.4 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 KXL47561.1 - 0.039 13.2 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.16 KXL47562.1 - 1.4e-16 60.4 34.9 1.4e-16 60.4 34.9 2.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sars6 PF12133.8 KXL47562.1 - 0.18 11.8 0.1 0.37 10.7 0.1 1.5 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus DUF5516 PF17637.2 KXL47562.1 - 0.76 9.6 8.5 0.14 11.9 2.9 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5516) adh_short_C2 PF13561.6 KXL47563.1 - 4.2e-24 85.4 0.0 5.6e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL47563.1 - 6.3e-24 84.5 0.0 9.2e-24 84.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Pex24p PF06398.11 KXL47564.1 - 5.7e-14 51.9 0.1 8e-14 51.4 0.1 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Mito_carr PF00153.27 KXL47565.1 - 4.5e-37 125.9 0.1 2.9e-17 62.4 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Glyco_transf_8 PF01501.20 KXL47566.1 - 1.6e-10 41.0 0.0 0.00014 21.6 0.1 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 8 Arf PF00025.21 KXL47567.1 - 1.4e-71 239.5 0.2 1.6e-71 239.4 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KXL47567.1 - 1e-13 51.6 0.0 1.4e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KXL47567.1 - 7.9e-13 48.2 0.0 9.8e-13 47.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KXL47567.1 - 2.8e-12 46.5 1.6 2.6e-08 33.5 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KXL47567.1 - 4.5e-11 42.6 0.0 4.9e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KXL47567.1 - 3.9e-09 36.2 0.0 4.6e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXL47567.1 - 0.00041 20.4 0.0 0.00059 19.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KXL47567.1 - 0.059 12.7 0.1 0.096 12.0 0.1 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DUF4185 PF13810.6 KXL47567.1 - 0.085 12.1 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4185) HET PF06985.11 KXL47568.1 - 1.1e-20 74.5 0.1 1.1e-20 74.5 0.1 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PMI_typeI PF01238.21 KXL47570.1 - 1.7e-140 468.5 0.0 2e-140 468.2 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I DUF1325 PF07039.11 KXL47571.1 - 2e-28 99.1 0.1 4.4e-28 98.0 0.0 1.6 2 0 0 2 2 2 1 SGF29 tudor-like domain Seryl_tRNA_N PF02403.22 KXL47571.1 - 0.012 15.8 4.2 0.012 15.8 4.2 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HEPN_AbiU2 PF18734.1 KXL47571.1 - 0.031 13.8 0.4 0.049 13.1 0.4 1.2 1 0 0 1 1 1 0 AbiU2 JAKMIP_CC3 PF16034.5 KXL47571.1 - 0.043 13.8 2.4 0.08 12.9 2.4 1.4 1 0 0 1 1 1 0 JAKMIP CC3 domain 4HB_MCP_1 PF12729.7 KXL47571.1 - 0.52 9.8 2.9 1.1 8.7 2.9 1.5 1 1 0 1 1 1 0 Four helix bundle sensory module for signal transduction DIRP PF06584.13 KXL47573.1 - 0.00025 21.2 0.1 0.00025 21.2 0.1 2.3 2 1 0 2 2 2 1 DIRP Spc7 PF08317.11 KXL47573.1 - 0.016 14.1 16.3 0.31 9.9 10.6 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein T3SS_ATPase_C PF18269.1 KXL47573.1 - 0.19 11.6 3.0 0.76 9.7 0.4 2.6 2 0 0 2 2 2 0 T3SS EscN ATPase C-terminal domain TSC22 PF01166.18 KXL47573.1 - 0.29 11.5 5.6 2.2 8.7 0.0 3.8 3 1 1 4 4 4 0 TSC-22/dip/bun family APH PF01636.23 KXL47573.1 - 0.55 10.1 6.3 0.067 13.1 1.9 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF4298 PF14131.6 KXL47573.1 - 0.73 9.8 7.5 0.19 11.7 1.6 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4298) GIT_CC PF16559.5 KXL47573.1 - 4.8 7.1 8.0 1 9.3 0.2 3.3 3 1 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Pex24p PF06398.11 KXL47574.1 - 5.8e-75 252.6 1.0 6.7e-75 252.4 1.0 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin IDO PF01231.18 KXL47575.1 - 8.9e-35 120.3 0.0 1e-34 120.1 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase PhyH PF05721.13 KXL47576.1 - 5.7e-10 39.8 0.0 7.7e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KXL47576.1 - 1.4e-09 37.3 0.1 0.0022 16.8 0.1 3.0 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) Asp PF00026.23 KXL47577.1 - 1.4e-69 235.0 3.6 1.6e-69 234.7 3.6 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXL47577.1 - 4.5e-12 46.6 0.5 1.6e-09 38.2 0.5 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KXL47577.1 - 0.0052 17.4 6.3 3.5 8.3 0.8 4.0 4 1 0 4 4 4 2 Aspartyl protease DLH PF01738.18 KXL47578.1 - 1e-16 61.1 0.5 1.2e-12 47.9 0.4 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family IDO PF01231.18 KXL47579.1 - 1.1e-119 400.1 0.0 1.2e-119 399.9 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Pcc1 PF09341.10 KXL47580.1 - 3.7e-30 103.9 2.4 8.1e-30 102.8 2.4 1.6 1 1 0 1 1 1 1 Transcription factor Pcc1 Glyco_hydro_28 PF00295.17 KXL47581.1 - 4.4e-118 394.1 16.9 5.5e-118 393.7 16.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 RNase_PH PF01138.21 KXL47582.1 - 1.7e-09 38.3 0.0 2.5e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 GST_N_4 PF17172.4 KXL47583.1 - 2.4e-16 60.3 0.0 3.8e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KXL47583.1 - 5.3e-15 55.0 0.0 1.2e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KXL47583.1 - 8.5e-08 32.6 0.0 2.3e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 Outer mitochondrial membrane transport complex protein SAM35 PF10806.8 KXL47583.1 - 0.00059 20.1 0.1 0.0012 19.1 0.1 1.5 1 0 0 1 1 1 1 SAM35, subunit of SAM coomplex GST_C_2 PF13410.6 KXL47583.1 - 0.0012 18.8 0.1 0.004 17.1 0.1 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_hydro_43 PF04616.14 KXL47584.1 - 6e-08 32.3 8.2 2e-07 30.6 8.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Bac_rhamnosid6H PF17389.2 KXL47585.1 - 1.5e-72 244.7 0.5 2e-72 244.3 0.5 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 KXL47585.1 - 2.2e-36 125.3 0.0 6e-36 123.9 0.0 1.7 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 KXL47585.1 - 4.9e-17 61.8 0.0 9e-17 60.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 KXL47585.1 - 6.8e-17 61.0 0.0 1.4e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain DUF2850 PF11012.8 KXL47585.1 - 0.024 14.9 0.0 0.096 13.0 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2850) tRNA_anti-codon PF01336.25 KXL47588.1 - 0.00031 20.6 0.0 0.00084 19.3 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain REPA_OB_2 PF16900.5 KXL47588.1 - 0.012 15.5 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 Replication protein A OB domain DUF4774 PF15999.5 KXL47588.1 - 0.016 15.0 0.1 0.032 14.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4774) CDC24_OB3 PF17244.2 KXL47588.1 - 0.03 14.1 0.1 0.091 12.4 0.0 1.8 2 0 0 2 2 2 0 Cell division control protein 24, OB domain 3 AMP-binding PF00501.28 KXL47589.1 - 2.6e-91 306.3 0.0 3.3e-91 306.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXL47589.1 - 1.4e-12 48.4 0.2 2.7e-12 47.5 0.2 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LRR_6 PF13516.6 KXL47591.1 - 0.00047 20.0 4.7 11 6.4 0.1 5.9 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.7 KXL47591.1 - 0.0013 19.1 2.5 1.6 9.2 0.0 3.5 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) PRCC PF10253.9 KXL47592.1 - 0.92 10.3 7.2 1.4 9.7 7.2 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Glyco_hydro_72 PF03198.14 KXL47593.1 - 5.9e-132 439.7 5.1 7.4e-132 439.4 5.1 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KXL47593.1 - 0.00012 21.6 0.2 0.001 18.6 0.2 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF2749 PF10907.8 KXL47593.1 - 0.048 13.8 1.0 0.048 13.8 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) Baculo_PEP_C PF04513.12 KXL47594.1 - 0.00019 21.5 6.1 0.023 14.7 0.7 2.3 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus WEMBL PF05701.11 KXL47594.1 - 0.00054 18.8 0.5 0.00068 18.5 0.5 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light DUF1664 PF07889.12 KXL47594.1 - 0.0039 17.2 0.1 0.21 11.6 0.0 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) DUF948 PF06103.11 KXL47594.1 - 0.0045 17.2 1.5 0.042 14.1 0.8 2.3 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 KXL47594.1 - 0.014 15.8 0.8 0.32 11.5 0.8 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein LPP PF04728.13 KXL47594.1 - 0.018 15.4 13.2 6.3 7.3 4.4 4.3 1 1 2 3 3 3 0 Lipoprotein leucine-zipper TPR_MLP1_2 PF07926.12 KXL47594.1 - 0.018 15.1 0.0 0.4 10.8 0.0 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Laminin_II PF06009.12 KXL47594.1 - 0.035 14.1 2.9 0.087 12.8 1.0 2.0 1 1 1 2 2 2 0 Laminin Domain II Atg14 PF10186.9 KXL47594.1 - 0.046 12.8 0.1 0.056 12.5 0.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Allexi_40kDa PF05549.11 KXL47594.1 - 0.18 11.3 2.0 0.23 10.9 1.4 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein StbA PF06406.11 KXL47594.1 - 0.19 10.9 3.5 0.24 10.6 3.5 1.3 1 0 0 1 1 1 0 StbA protein DUF883 PF05957.13 KXL47594.1 - 0.82 10.3 8.4 0.9 10.2 2.1 2.9 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF883) Lectin_N PF03954.14 KXL47594.1 - 2 8.2 6.0 6.5 6.5 3.0 2.1 1 1 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF677 PF05055.12 KXL47594.1 - 5.1 5.9 9.2 3 6.7 0.1 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF677) MIF4G PF02854.19 KXL47596.1 - 1.3e-59 201.5 1.5 1.5e-32 113.0 0.1 3.4 4 0 0 4 4 4 2 MIF4G domain Upf2 PF04050.14 KXL47596.1 - 1.4e-39 136.0 4.9 1.4e-39 136.0 4.9 2.9 2 0 0 2 2 2 1 Up-frameshift suppressor 2 ResIII PF04851.15 KXL47597.1 - 6.7e-23 81.5 0.2 1.7e-22 80.2 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXL47597.1 - 9.2e-15 55.0 0.0 1.1e-13 51.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXL47597.1 - 2.4e-14 53.5 0.0 4.5e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KXL47597.1 - 3.1e-05 23.8 0.0 7.2e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 KXL47597.1 - 0.00067 19.0 0.0 0.0014 17.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KXL47597.1 - 0.0056 17.0 0.1 0.069 13.4 0.1 2.7 2 1 0 2 2 2 1 AAA domain ERCC3_RAD25_C PF16203.5 KXL47597.1 - 0.0066 15.7 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF87 PF01935.17 KXL47597.1 - 0.034 14.2 0.5 1 9.4 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain Transglut_core PF01841.19 KXL47597.1 - 0.088 13.3 0.0 0.38 11.2 0.0 2.0 2 0 0 2 2 2 0 Transglutaminase-like superfamily Helicase_RecD PF05127.14 KXL47597.1 - 0.11 12.4 0.1 0.33 10.8 0.0 1.8 2 0 0 2 2 2 0 Helicase Phosphorylase PF00343.20 KXL47598.1 - 0 1065.2 0.0 0 1065.0 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase CTP_transf_1 PF01148.20 KXL47599.1 - 2.5e-81 273.3 24.5 3.1e-81 273.0 24.5 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family AA_permease_C PF13906.6 KXL47599.1 - 0.064 13.3 7.5 3.3 7.8 0.5 4.2 3 0 0 3 3 3 0 C-terminus of AA_permease DUF3636 PF12331.8 KXL47600.1 - 2.3e-44 150.8 0.1 4.2e-44 150.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) LCD1 PF09798.9 KXL47600.1 - 0.0035 15.9 1.4 0.033 12.7 0.6 2.2 2 0 0 2 2 2 1 DNA damage checkpoint protein FAM76 PF16046.5 KXL47600.1 - 0.23 10.8 9.1 0.038 13.3 4.8 1.7 2 0 0 2 2 2 0 FAM76 protein DivIC PF04977.15 KXL47600.1 - 3.7 7.4 8.0 5.7 6.8 0.7 2.7 2 0 0 2 2 2 0 Septum formation initiator NAD_binding_2 PF03446.15 KXL47601.1 - 2.2e-34 118.9 0.0 3.3e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXL47601.1 - 8.5e-21 74.4 0.0 1.4e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KXL47601.1 - 0.011 16.3 0.0 0.021 15.4 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF656 PF04920.12 KXL47601.1 - 0.063 13.2 0.0 0.32 10.9 0.0 2.1 3 0 0 3 3 3 0 Family of unknown function (DUF656) PGAP1 PF07819.13 KXL47602.1 - 7.4e-89 297.4 0.0 1.1e-88 296.8 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KXL47602.1 - 3.3e-06 27.9 1.4 5.1e-06 27.2 0.3 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXL47602.1 - 0.0016 18.1 0.1 0.0036 17.0 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXL47602.1 - 0.002 17.4 0.0 0.0045 16.3 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Palm_thioest PF02089.15 KXL47602.1 - 0.003 17.4 0.0 0.011 15.6 0.0 2.0 2 0 0 2 2 2 1 Palmitoyl protein thioesterase DUF676 PF05057.14 KXL47602.1 - 0.007 15.9 0.1 0.014 14.9 0.1 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.15 KXL47602.1 - 0.028 13.6 0.0 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Peptidase_M78 PF06114.13 KXL47602.1 - 0.16 11.9 0.0 0.43 10.5 0.0 1.6 1 0 0 1 1 1 0 IrrE N-terminal-like domain SPRY PF00622.28 KXL47604.1 - 1.5e-18 67.1 0.0 2.3e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 SPRY domain Cullin PF00888.22 KXL47605.1 - 8.7e-183 609.3 13.9 1.2e-182 608.8 13.9 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KXL47605.1 - 1.2e-26 92.5 4.2 1.2e-26 92.5 4.2 2.6 2 0 0 2 2 2 1 Cullin protein neddylation domain NDUF_C2 PF06374.11 KXL47605.1 - 0.062 13.5 0.3 0.2 11.8 0.3 1.9 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) CHCH PF06747.13 KXL47606.1 - 9e-06 25.7 3.8 1.7e-05 24.8 3.8 1.5 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 KXL47606.1 - 7e-05 23.2 1.4 0.00013 22.3 1.4 1.4 1 0 0 1 1 1 1 GCK domain TPK_catalytic PF04263.16 KXL47607.1 - 5.3e-28 97.5 0.0 7.9e-28 96.9 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 KXL47607.1 - 3.1e-18 65.2 0.1 7.8e-18 64.0 0.0 1.7 2 0 0 2 2 2 1 Thiamin pyrophosphokinase, vitamin B1 binding domain HEAT_EZ PF13513.6 KXL47608.1 - 8e-29 99.7 11.6 1e-12 48.3 0.0 9.6 8 1 2 10 10 10 4 HEAT-like repeat HEAT PF02985.22 KXL47608.1 - 2e-24 83.6 14.5 0.0058 16.8 0.1 10.7 11 0 0 11 11 11 6 HEAT repeat HEAT_2 PF13646.6 KXL47608.1 - 2.4e-23 82.3 2.0 1.6e-08 34.8 0.0 7.4 7 1 1 8 8 7 3 HEAT repeats Vac14_Fab1_bd PF12755.7 KXL47608.1 - 1.8e-15 57.3 0.0 0.024 15.2 0.0 7.0 5 2 2 7 7 7 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KXL47608.1 - 1.1e-12 48.3 0.6 0.003 17.6 0.0 4.9 4 1 1 5 5 5 4 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 KXL47608.1 - 3.8e-09 36.3 0.2 1.9e-07 30.9 0.0 4.0 4 1 0 4 4 4 1 Importin-beta N-terminal domain Arm PF00514.23 KXL47608.1 - 9.4e-05 22.3 5.2 2.3 8.4 0.0 5.7 6 0 0 6 6 5 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 KXL47608.1 - 0.0003 19.5 0.1 0.6 8.6 0.0 3.5 3 1 0 3 3 3 2 Adaptin N terminal region TAF6_C PF07571.13 KXL47608.1 - 0.00045 20.5 0.0 0.46 10.8 0.0 4.0 4 0 0 4 4 4 1 TAF6 C-terminal HEAT repeat domain Tti2 PF10521.9 KXL47608.1 - 0.0017 17.9 0.8 0.23 11.0 0.0 3.3 3 0 0 3 3 3 1 Tti2 family HEAT_PBS PF03130.16 KXL47608.1 - 0.024 15.3 6.3 0.61 10.9 0.0 5.2 6 0 0 6 6 4 0 PBS lyase HEAT-like repeat Nipped-B_C PF12830.7 KXL47608.1 - 0.043 13.8 0.2 8.6 6.3 0.0 4.1 6 0 0 6 6 6 0 Sister chromatid cohesion C-terminus Phage_TTP_13 PF16463.5 KXL47608.1 - 0.046 13.3 0.0 0.091 12.3 0.0 1.5 1 0 0 1 1 1 0 Phage tail tube protein family MMS19_C PF12460.8 KXL47608.1 - 0.05 12.7 4.8 1.7 7.7 0.4 4.5 5 1 0 5 5 5 0 RNAPII transcription regulator C-terminal IFRD PF05004.13 KXL47608.1 - 0.077 12.1 0.0 13 4.8 0.0 3.3 4 0 0 4 4 4 0 Interferon-related developmental regulator (IFRD) Cohesin_HEAT PF12765.7 KXL47608.1 - 0.084 13.2 0.0 27 5.2 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Xpo1 PF08389.12 KXL47608.1 - 0.13 12.4 0.2 2.3 8.3 0.0 3.3 3 2 1 4 4 4 0 Exportin 1-like protein UPF0253 PF06786.12 KXL47608.1 - 0.16 12.3 0.6 9.1 6.6 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0253) E1-E2_ATPase PF00122.20 KXL47609.1 - 2.3e-20 72.9 0.0 5.8e-20 71.6 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KXL47609.1 - 1.2e-15 58.4 0.8 8e-10 39.4 0.7 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KXL47609.1 - 0.013 15.3 0.1 0.035 13.8 0.1 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXL47609.1 - 0.055 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus FAD_binding_3 PF01494.19 KXL47610.1 - 5e-11 42.5 0.3 0.0018 17.6 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain Pyr_redox_2 PF07992.14 KXL47610.1 - 5.9e-06 25.7 0.5 0.00097 18.5 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXL47610.1 - 2.7e-05 23.5 0.1 4e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXL47610.1 - 0.0001 22.5 0.1 0.00026 21.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXL47610.1 - 0.00013 20.8 0.1 0.004 15.9 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KXL47610.1 - 0.00021 20.7 0.0 0.0004 19.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KXL47610.1 - 0.0031 16.7 0.0 0.0089 15.1 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.24 KXL47610.1 - 0.0062 16.2 0.2 0.014 15.0 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXL47610.1 - 0.013 14.7 0.0 0.16 11.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXL47610.1 - 0.23 10.5 0.4 1.7 7.6 0.4 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein adh_short PF00106.25 KXL47611.1 - 9.3e-22 77.4 0.0 6.1e-17 61.7 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXL47611.1 - 1.6e-15 57.4 0.0 3.9e-11 43.0 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL47611.1 - 2.4e-06 27.6 0.3 4.8e-06 26.6 0.3 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXL47611.1 - 0.031 13.4 0.1 0.046 12.8 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 KXL47611.1 - 0.045 13.8 0.1 0.092 12.8 0.1 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KXL47611.1 - 0.092 13.0 0.2 0.17 12.2 0.2 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Sugar_tr PF00083.24 KXL47612.1 - 4.2e-79 266.5 23.5 5e-79 266.3 23.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL47612.1 - 1.1e-20 73.8 30.2 1.1e-20 73.8 30.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXL47612.1 - 0.04 12.2 7.7 0.45 8.7 6.9 2.4 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.22 KXL47613.1 - 6.6e-67 226.2 0.0 8.4e-67 225.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Na_Ca_ex PF01699.24 KXL47614.1 - 2.9e-37 127.9 36.2 3.7e-19 69.2 14.1 2.0 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Lig_chan PF00060.26 KXL47614.1 - 2.1 8.2 4.1 5.7 6.8 0.8 2.7 2 1 0 2 2 2 0 Ligand-gated ion channel Pox_P21 PF05313.12 KXL47614.1 - 3.5 7.2 8.9 0.059 12.9 0.5 2.2 3 0 0 3 3 3 0 Poxvirus P21 membrane protein Myb_DNA-binding PF00249.31 KXL47615.1 - 0.044 14.0 0.0 0.074 13.3 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Sulfate_transp PF00916.20 KXL47616.1 - 5.9e-36 124.0 0.8 4.1e-35 121.2 0.8 2.0 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KXL47616.1 - 5.6e-16 58.2 0.0 9.3e-16 57.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KXL47616.1 - 0.00039 20.8 1.8 0.00086 19.7 1.8 1.6 1 0 0 1 1 1 1 Molybdate transporter of MFS superfamily Ank_2 PF12796.7 KXL47617.1 - 1.6e-08 35.0 0.0 2.3e-05 24.9 0.0 2.6 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXL47617.1 - 2.8e-07 31.0 0.2 0.0017 18.9 0.0 4.1 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXL47617.1 - 1.2e-06 28.3 0.1 2.1 9.2 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KXL47617.1 - 0.00012 22.3 0.2 12 6.3 0.0 4.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) DUF2083 PF09856.9 KXL47617.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Predicted transcriptional regulator (DUF2083) End3 PF12761.7 KXL47618.1 - 1.2e-77 260.6 2.3 1.7e-77 260.1 2.3 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 KXL47618.1 - 5.7e-49 164.4 0.1 7.5e-48 160.8 0.2 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KXL47618.1 - 9.6e-08 31.1 0.5 5.7e-07 28.6 0.3 2.3 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KXL47618.1 - 8.1e-07 29.4 0.1 2.9e-06 27.6 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KXL47618.1 - 2.9e-06 27.0 0.1 0.0002 21.1 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KXL47618.1 - 2.9e-05 23.7 0.8 0.002 17.9 0.2 3.6 4 0 0 4 4 3 1 EF-hand domain EF-hand_5 PF13202.6 KXL47618.1 - 0.003 17.0 0.0 0.013 15.0 0.0 2.1 1 0 0 1 1 1 1 EF hand SKA1 PF07160.12 KXL47618.1 - 0.1 12.4 3.7 0.12 12.2 0.3 2.1 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Syntaxin-6_N PF09177.11 KXL47618.1 - 0.12 13.0 4.6 4.7 7.8 4.6 2.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal CSN5_C PF18323.1 KXL47618.1 - 0.22 12.5 3.0 0.68 10.9 3.0 1.9 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain DUF4140 PF13600.6 KXL47618.1 - 0.23 11.9 3.4 11 6.5 0.1 2.6 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) CorA PF01544.18 KXL47618.1 - 0.23 10.7 4.7 0.36 10.1 4.7 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Phlebovirus_NSM PF07246.11 KXL47618.1 - 0.33 10.3 2.8 0.55 9.6 2.8 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M FlaC_arch PF05377.11 KXL47618.1 - 0.47 10.9 5.9 5.6 7.4 0.2 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF16 PF01519.16 KXL47618.1 - 0.72 10.4 8.4 0.61 10.6 1.9 2.4 1 1 0 2 2 2 0 Protein of unknown function DUF16 Adaptin_binding PF10199.9 KXL47618.1 - 1.1 9.9 6.4 2.6 8.7 6.4 1.6 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 FliJ PF02050.16 KXL47618.1 - 2.2 8.5 10.1 0.3 11.3 2.6 2.3 1 1 0 2 2 2 0 Flagellar FliJ protein UPF0242 PF06785.11 KXL47618.1 - 4.8 7.2 7.4 8.8 6.4 7.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 KXL47618.1 - 5.5 6.3 5.9 8 5.7 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Thiolase_N PF00108.23 KXL47619.1 - 2.7e-69 233.4 0.0 3.3e-69 233.2 0.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXL47619.1 - 6.9e-42 142.0 0.1 6.9e-42 142.0 0.1 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXL47619.1 - 0.024 14.2 0.5 0.097 12.2 0.2 2.1 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KXL47619.1 - 0.12 12.2 0.0 20 5.2 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III AcetylCoA_hydro PF02550.15 KXL47620.1 - 1.5e-49 168.7 0.0 2.2e-49 168.1 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 KXL47620.1 - 2.1e-42 144.7 0.0 4e-42 143.7 0.0 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain BAR_2 PF10455.9 KXL47621.1 - 1.9e-53 181.5 0.1 2.7e-53 181.0 0.1 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KXL47621.1 - 8.7e-21 74.7 4.3 2.1e-19 70.1 4.3 2.1 1 1 0 1 1 1 1 BAR domain P53_TAD PF08563.11 KXL47621.1 - 0.077 12.5 0.0 2.5 7.7 0.0 2.4 2 0 0 2 2 2 0 P53 transactivation motif Mis12 PF05859.12 KXL47621.1 - 0.43 10.6 3.6 13 5.8 0.8 2.7 2 1 1 3 3 3 0 Mis12 protein DUF5082 PF16888.5 KXL47621.1 - 1.7 9.0 5.6 3.6 7.9 0.6 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) DUF2564 PF10819.8 KXL47621.1 - 2.3 8.7 7.0 2.8 8.4 3.0 3.0 2 1 2 4 4 4 0 Protein of unknown function (DUF2564) Pex19 PF04614.12 KXL47621.1 - 4.5 7.0 7.0 0.67 9.7 0.2 2.1 1 1 1 2 2 2 0 Pex19 protein family tRNA_int_endo PF01974.17 KXL47624.1 - 4.6e-19 68.3 0.4 1.4e-18 66.8 0.4 1.8 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 KXL47624.1 - 1.4e-05 24.6 0.0 0.008 15.8 0.0 2.9 3 0 0 3 3 3 2 tRNA intron endonuclease, N-terminal domain Peptidase_C48 PF02902.19 KXL47625.1 - 5.5e-06 26.4 0.2 6.2e-06 26.2 0.2 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain IF4E PF01652.18 KXL47627.1 - 9.2e-53 178.3 0.0 1.6e-52 177.5 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E PGAP1 PF07819.13 KXL47628.1 - 6.8e-05 22.7 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein ANAPC4_WD40 PF12894.7 KXL47628.1 - 0.00047 20.4 1.2 0.69 10.3 0.0 5.0 5 1 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain DUF676 PF05057.14 KXL47628.1 - 0.0031 17.1 0.3 0.0076 15.8 0.0 1.8 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KXL47628.1 - 0.018 14.3 0.0 0.036 13.3 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXL47628.1 - 0.03 14.9 0.0 0.072 13.7 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family WD40 PF00400.32 KXL47628.1 - 0.12 13.3 0.2 94 4.1 0.1 5.5 5 1 0 5 5 5 0 WD domain, G-beta repeat Hira PF07569.11 KXL47628.1 - 0.12 12.1 0.1 0.55 9.9 0.0 2.2 2 0 0 2 2 2 0 TUP1-like enhancer of split Pkinase PF00069.25 KXL47630.1 - 7.4e-67 225.5 0.0 1.1e-66 225.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL47630.1 - 5.1e-45 153.8 0.0 7.5e-45 153.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXL47630.1 - 7.2e-05 21.7 0.0 0.00019 20.3 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXL47630.1 - 0.0028 17.0 0.0 0.01 15.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KXL47630.1 - 0.0087 16.0 0.0 2.3 8.0 0.0 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXL47630.1 - 0.38 9.6 1.1 1.1 8.2 0.0 2.2 2 1 0 2 2 2 0 Haspin like kinase domain Abhydrolase_2 PF02230.16 KXL47631.1 - 1.4e-19 70.8 0.0 1.8e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 KXL47631.1 - 0.00029 20.5 0.0 0.00082 19.1 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KXL47631.1 - 0.00083 20.0 0.1 0.001 19.8 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXL47631.1 - 0.018 14.3 0.0 2.5 7.3 0.0 2.4 2 1 1 3 3 3 0 Serine aminopeptidase, S33 Palm_thioest PF02089.15 KXL47631.1 - 0.034 14.0 0.0 0.052 13.4 0.0 1.3 1 1 0 1 1 1 0 Palmitoyl protein thioesterase DUF3759 PF12585.8 KXL47632.1 - 7.9e-41 138.0 3.5 1e-40 137.6 3.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF3824 PF12868.7 KXL47632.1 - 0.0064 17.2 4.9 0.085 13.5 4.9 2.1 1 1 0 1 1 1 1 Domain of unknwon function (DUF3824) Serine_protease PF18405.1 KXL47632.1 - 0.051 12.7 0.0 0.064 12.4 0.0 1.0 1 0 0 1 1 1 0 Gammaproteobacterial serine protease HDA2-3 PF11496.8 KXL47633.1 - 1.8e-18 66.8 0.0 3.5e-16 59.2 0.0 2.5 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 MnmE_helical PF12631.7 KXL47634.1 - 0.0059 16.8 0.0 0.034 14.3 0.0 2.4 1 1 0 1 1 1 1 MnmE helical domain zf-C2H2 PF00096.26 KXL47634.1 - 0.011 16.1 0.6 0.011 16.1 0.6 4.8 4 0 0 4 4 4 0 Zinc finger, C2H2 type NOG1_N PF17835.1 KXL47634.1 - 0.17 11.8 1.8 0.33 10.9 1.8 1.4 1 0 0 1 1 1 0 NOG1 N-terminal helical domain APG6_N PF17675.1 KXL47634.1 - 0.29 11.6 11.9 0.9 10.1 11.9 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region zf-C2H2_4 PF13894.6 KXL47634.1 - 2.4 9.2 21.2 5.6 8.1 1.0 5.5 5 0 0 5 5 5 0 C2H2-type zinc finger SlyX PF04102.12 KXL47634.1 - 3.8 8.2 11.8 17 6.1 11.8 2.2 1 0 0 1 1 1 0 SlyX DUF2333 PF10095.9 KXL47634.1 - 9.9 5.1 7.6 21 4.0 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2333) Acetyltransf_10 PF13673.7 KXL47635.1 - 6.6e-05 22.9 0.1 0.00015 21.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXL47635.1 - 0.00063 20.1 0.0 0.00087 19.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXL47635.1 - 0.0052 17.0 0.0 0.0067 16.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Fringe PF02434.16 KXL47636.1 - 0.00016 21.2 0.1 0.0024 17.4 0.1 2.1 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.6 KXL47636.1 - 0.00033 20.5 0.5 0.0011 18.8 0.5 1.9 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 KXL47636.1 - 0.017 15.0 0.2 0.034 14.1 0.2 1.4 1 0 0 1 1 1 0 PAN domain PAN_2 PF08276.11 KXL47636.1 - 0.072 13.2 1.1 0.14 12.3 1.1 1.4 1 0 0 1 1 1 0 PAN-like domain CMD PF02627.20 KXL47639.1 - 3.2e-09 36.7 0.2 1.6e-07 31.2 0.0 2.2 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family THDPS_N_2 PF14805.6 KXL47639.1 - 0.08 13.2 0.6 0.17 12.1 0.0 1.9 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal CDC14 PF08045.11 KXL47640.1 - 1.5e-107 359.0 0.9 1.8e-107 358.7 0.9 1.1 1 0 0 1 1 1 1 Cell division control protein 14, SIN component Transketolase_N PF00456.21 KXL47641.1 - 1.2e-153 511.0 0.0 1.6e-153 510.6 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KXL47641.1 - 1.3e-45 155.2 0.0 2.3e-45 154.4 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KXL47641.1 - 2.6e-13 49.9 0.0 5.1e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KXL47641.1 - 0.00018 20.8 0.0 0.00031 20.0 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 KXL47641.1 - 0.0092 15.0 0.1 0.015 14.2 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Beta_elim_lyase PF01212.21 KXL47641.1 - 0.02 14.2 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase GtrA PF04138.14 KXL47641.1 - 0.13 12.5 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 GtrA-like protein CFEM PF05730.11 KXL47642.1 - 2.4e-05 24.3 6.2 4.2e-05 23.6 6.2 1.4 1 0 0 1 1 1 1 CFEM domain Podoplanin PF05808.11 KXL47642.1 - 0.0099 16.0 5.8 0.027 14.6 5.8 1.7 1 0 0 1 1 1 1 Podoplanin RIFIN PF02009.16 KXL47642.1 - 0.058 13.3 0.0 0.089 12.7 0.0 1.2 1 0 0 1 1 1 0 Rifin Gpr1_Fun34_YaaH PF01184.19 KXL47644.1 - 2.1e-37 128.8 26.3 2.5e-37 128.5 26.3 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Sugar_tr PF00083.24 KXL47645.1 - 1.1e-81 275.0 27.8 1.3e-81 274.8 27.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL47645.1 - 2e-21 76.3 29.6 2e-21 76.3 29.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXL47645.1 - 0.00027 19.9 6.9 0.00061 18.8 6.9 1.6 1 0 0 1 1 1 1 MFS_1 like family Zn_clus PF00172.18 KXL47646.1 - 3.3e-09 36.7 9.1 6.4e-09 35.8 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KXL47647.1 - 1.7e-86 290.9 23.5 2e-86 290.7 23.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL47647.1 - 2.8e-21 75.8 43.5 2.5e-13 49.7 16.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXL47647.1 - 0.0035 15.8 3.5 0.0035 15.8 3.5 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KXL47647.1 - 1.4 7.1 9.9 0.68 8.2 2.4 3.0 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 KXL47648.1 - 4.3e-99 332.4 27.5 5.3e-99 332.1 27.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL47648.1 - 5.3e-25 88.1 31.4 7.5e-25 87.6 31.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXL47648.1 - 0.00013 20.5 4.9 0.00013 20.5 4.9 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2530 PF10745.9 KXL47648.1 - 1.4 9.2 4.9 0.51 10.6 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) RSN1_7TM PF02714.15 KXL47650.1 - 2e-81 273.3 25.7 3.6e-81 272.5 25.7 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KXL47650.1 - 2e-42 144.6 2.8 2e-42 144.6 2.8 2.9 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KXL47650.1 - 9.4e-27 94.4 2.8 3.2e-15 56.8 0.0 2.6 3 0 0 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KXL47650.1 - 3.1e-11 43.3 0.0 6e-09 36.0 0.0 2.9 1 1 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter HSP70 PF00012.20 KXL47652.1 - 4.7e-57 193.5 8.5 1.3e-54 185.4 0.0 3.5 2 2 1 3 3 3 2 Hsp70 protein PI3K_1B_p101 PF10486.9 KXL47652.1 - 0.11 10.2 4.7 0.2 9.4 4.7 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Sugar_tr PF00083.24 KXL47653.1 - 1.2e-89 301.2 20.6 1.4e-89 301.0 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL47653.1 - 2.7e-27 95.6 42.1 4.4e-26 91.6 26.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXL47653.1 - 0.66 8.2 13.3 3.3 5.9 5.1 3.3 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF3693 PF12472.8 KXL47653.1 - 0.66 9.7 2.5 3.2 7.5 0.0 3.0 3 0 0 3 3 3 0 Phage related protein Abhydrolase_1 PF00561.20 KXL47654.1 - 0.00043 20.0 0.0 0.00055 19.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold WD40 PF00400.32 KXL47658.1 - 1.4e-29 101.7 14.8 4.4e-07 30.5 0.2 7.9 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL47658.1 - 2.4e-09 37.4 1.2 0.0002 21.6 0.0 4.5 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain zf-NOSIP PF15906.5 KXL47658.1 - 0.18 12.0 0.0 0.39 10.9 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein DEAD PF00270.29 KXL47659.1 - 5e-17 62.2 0.0 9.6e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXL47659.1 - 1.2e-13 51.4 0.0 5.7e-11 42.7 0.0 2.8 3 0 0 3 3 3 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KXL47659.1 - 9.3e-12 45.5 3.1 2.3e-11 44.3 3.1 1.7 1 0 0 1 1 1 1 RecQ zinc-binding Glyco_hydro_1 PF00232.18 KXL47662.1 - 6.3e-159 529.2 0.8 7.7e-159 528.9 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 DUF1479 PF07350.12 KXL47663.1 - 8.3e-160 532.1 0.0 9.9e-160 531.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 KXL47663.1 - 0.11 12.8 0.1 10 6.3 0.0 2.5 3 0 0 3 3 3 0 Phytanoyl-CoA dioxygenase (PhyH) Sugar_tr PF00083.24 KXL47664.1 - 1.2e-95 321.0 30.0 1.4e-95 320.8 30.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL47664.1 - 1.6e-21 76.6 37.5 3.1e-20 72.4 23.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TLP1_add_C PF18313.1 KXL47665.1 - 2.2e-27 94.8 0.1 5.5e-27 93.5 0.0 1.7 2 0 0 2 2 2 1 Thiolase-like protein type 1 additional C-terminal domain Septin PF00735.18 KXL47666.1 - 1.1e-121 405.5 0.2 1.1e-121 405.5 0.2 1.8 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KXL47666.1 - 2.1e-08 34.2 0.9 4.9e-08 33.1 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXL47666.1 - 6.1e-07 29.2 1.4 0.00019 21.1 0.0 3.0 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Roc PF08477.13 KXL47666.1 - 0.00026 21.2 0.0 0.00063 20.0 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 KXL47666.1 - 0.0003 21.3 2.5 0.021 15.3 0.0 2.7 3 0 0 3 3 3 1 ABC transporter AIG1 PF04548.16 KXL47666.1 - 0.00077 18.8 1.6 0.0013 18.1 0.0 2.1 2 0 0 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 KXL47666.1 - 0.0015 18.5 0.6 0.0015 18.5 0.6 3.6 3 1 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 KXL47666.1 - 0.0019 18.6 0.0 0.0057 17.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Ras PF00071.22 KXL47666.1 - 0.0032 17.1 0.0 0.011 15.3 0.0 1.9 1 0 0 1 1 1 1 Ras family AAA_22 PF13401.6 KXL47666.1 - 0.0049 17.2 0.9 0.02 15.2 0.0 2.5 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KXL47666.1 - 0.013 15.3 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KXL47666.1 - 0.041 13.4 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 KXL47666.1 - 0.054 12.9 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 KXL47666.1 - 0.064 13.0 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KXL47666.1 - 0.076 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 KXL47666.1 - 0.11 12.9 1.0 0.41 11.1 0.0 2.4 3 0 0 3 3 2 0 RNA helicase Exonuc_VII_L PF02601.15 KXL47666.1 - 0.28 10.7 6.5 0.51 9.8 6.5 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 KXL47666.1 - 0.36 9.9 8.1 0.53 9.3 8.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF87 PF01935.17 KXL47666.1 - 0.49 10.5 5.4 5.3 7.1 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain Dynamin_N PF00350.23 KXL47666.1 - 0.58 10.2 12.4 0.99 9.4 0.1 3.6 2 2 1 3 3 3 0 Dynamin family ATP_bind_1 PF03029.17 KXL47666.1 - 0.86 9.3 7.0 1.5 8.5 0.0 3.1 2 1 1 3 3 2 0 Conserved hypothetical ATP binding protein UPF0242 PF06785.11 KXL47666.1 - 3.6 7.6 15.9 7.3 6.7 15.9 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exo70 PF03081.15 KXL47667.1 - 1.8e-91 307.0 0.0 2.9e-91 306.3 0.0 1.3 1 0 0 1 1 1 1 Exo70 exocyst complex subunit CagA PF03507.13 KXL47667.1 - 0.0024 17.9 0.1 0.19 11.6 0.0 2.5 2 0 0 2 2 2 1 CagA exotoxin ApoLp-III PF07464.11 KXL47667.1 - 0.012 15.8 3.9 0.38 10.8 1.6 3.2 3 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Prominin PF05478.11 KXL47667.1 - 0.046 11.7 0.4 0.2 9.5 0.2 1.8 2 0 0 2 2 2 0 Prominin DASH_Dam1 PF08653.10 KXL47667.1 - 0.084 12.7 1.1 20 5.0 0.0 4.6 5 0 0 5 5 5 0 DASH complex subunit Dam1 TACC_C PF05010.14 KXL47667.1 - 0.32 10.7 1.9 3.2 7.5 0.4 2.7 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal PLA2_B PF01735.18 KXL47668.1 - 6.6e-21 74.3 0.0 1e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Lysophospholipase catalytic domain SKN1 PF03935.15 KXL47669.1 - 1.1e-222 739.9 8.4 1.2e-222 739.8 8.4 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) PMP1_2 PF08114.11 KXL47669.1 - 1.1 9.0 3.5 2.3 8.0 3.5 1.4 1 0 0 1 1 1 0 ATPase proteolipid family Sigma70_ner PF04546.13 KXL47670.1 - 0.011 15.6 1.3 0.012 15.5 1.3 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.9 KXL47670.1 - 0.026 13.7 15.0 0.031 13.4 15.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FAM176 PF14851.6 KXL47670.1 - 0.033 13.8 3.4 0.045 13.4 3.4 1.2 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.12 KXL47670.1 - 0.062 11.5 2.9 0.062 11.5 2.9 1.0 1 0 0 1 1 1 0 Nop14-like family TFB6 PF17110.5 KXL47670.1 - 0.087 12.6 2.9 0.12 12.1 2.9 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Sporozoite_P67 PF05642.11 KXL47670.1 - 0.089 10.9 2.8 0.098 10.7 2.8 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Tom22 PF04281.13 KXL47670.1 - 0.13 12.0 3.1 0.18 11.6 3.1 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 eIF-3c_N PF05470.12 KXL47670.1 - 0.14 10.5 1.3 0.13 10.6 1.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SDA1 PF05285.12 KXL47670.1 - 0.25 10.7 4.7 0.26 10.7 4.7 1.1 1 0 0 1 1 1 0 SDA1 Utp14 PF04615.13 KXL47670.1 - 0.26 9.8 4.4 0.29 9.7 4.4 1.0 1 0 0 1 1 1 0 Utp14 protein DNA_pol_phi PF04931.13 KXL47670.1 - 0.26 9.3 10.9 0.29 9.2 10.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi RXT2_N PF08595.11 KXL47670.1 - 0.33 11.0 5.9 0.43 10.6 5.9 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 KXL47670.1 - 0.35 11.3 22.7 0.79 10.1 22.7 1.6 1 1 0 1 1 1 0 Centromere protein B dimerisation domain CDC45 PF02724.14 KXL47670.1 - 0.45 8.7 5.5 0.49 8.6 5.5 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 KXL47670.1 - 0.75 10.2 14.9 1.3 9.4 14.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GCIP PF13324.6 KXL47670.1 - 1.6 8.3 6.4 1.8 8.1 6.4 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting NOA36 PF06524.12 KXL47670.1 - 1.7 7.9 19.8 2.2 7.5 19.8 1.1 1 0 0 1 1 1 0 NOA36 protein RRN3 PF05327.11 KXL47670.1 - 4.1 5.8 7.7 4.6 5.7 7.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4611 PF15387.6 KXL47670.1 - 8.5 6.7 11.6 15 5.8 11.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NMT_C PF02799.15 KXL47671.1 - 2e-75 252.9 0.0 2.6e-75 252.5 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KXL47671.1 - 1.4e-67 226.5 0.0 5e-66 221.5 0.0 2.1 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_1 PF00583.25 KXL47671.1 - 0.0019 18.4 0.1 0.011 15.9 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KXL47671.1 - 0.049 13.7 0.1 0.25 11.4 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Amidohydro_3 PF07969.11 KXL47672.1 - 3.8e-25 89.3 0.0 2.2e-24 86.8 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KXL47672.1 - 6.8e-07 28.9 0.3 0.0019 17.6 0.0 3.2 3 1 0 3 3 3 2 Amidohydrolase family AP_endonuc_2 PF01261.24 KXL47672.1 - 0.003 17.0 0.0 0.97 8.8 0.0 2.4 2 0 0 2 2 2 2 Xylose isomerase-like TIM barrel ABC_tran PF00005.27 KXL47673.1 - 2.9e-44 150.9 0.0 1.4e-23 83.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXL47673.1 - 1.5e-35 123.2 26.3 1.2e-26 94.0 9.5 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.6 KXL47673.1 - 1.1e-10 41.8 0.1 0.038 13.8 0.0 4.4 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXL47673.1 - 1.1e-08 34.8 1.0 0.0071 15.8 0.1 3.9 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXL47673.1 - 0.00013 21.6 0.2 0.11 12.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KXL47673.1 - 0.00013 22.2 0.1 0.43 10.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KXL47673.1 - 0.00018 21.9 0.1 0.72 10.2 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KXL47673.1 - 0.0004 20.5 0.1 0.15 12.2 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KXL47673.1 - 0.0021 18.6 0.0 3.5 8.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 KXL47673.1 - 0.0041 16.2 0.2 0.4 9.7 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 KXL47673.1 - 0.0042 16.7 0.0 3.3 7.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KXL47673.1 - 0.0063 17.0 1.0 0.15 12.5 0.2 2.3 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 KXL47673.1 - 0.0066 15.3 1.1 0.086 11.6 0.1 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 KXL47673.1 - 0.011 15.7 0.6 3.4 7.6 0.1 2.7 2 0 0 2 2 2 0 RsgA GTPase RNA_helicase PF00910.22 KXL47673.1 - 0.013 15.9 0.0 6.7 7.2 0.0 2.8 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.18 KXL47673.1 - 0.014 14.8 0.2 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.17 KXL47673.1 - 0.017 15.2 0.5 0.7 9.9 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_24 PF13479.6 KXL47673.1 - 0.025 14.3 0.0 0.68 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KXL47673.1 - 0.027 13.8 0.2 2.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_15 PF13175.6 KXL47673.1 - 0.046 13.4 0.2 1.2 8.7 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain PRK PF00485.18 KXL47673.1 - 0.08 12.7 0.0 0.44 10.3 0.0 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Dynamin_N PF00350.23 KXL47673.1 - 0.15 12.1 0.5 1.6 8.8 0.0 2.2 2 0 0 2 2 2 0 Dynamin family adh_short PF00106.25 KXL47675.1 - 5.3e-12 45.6 0.0 9.9e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL47675.1 - 2e-06 27.9 0.0 3.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KXL47675.1 - 1.9e-05 24.4 0.0 3.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Sacchrp_dh_NADP PF03435.18 KXL47675.1 - 0.0042 17.3 0.1 0.0095 16.2 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KXL47675.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 KXL47675.1 - 0.13 12.3 0.0 0.3 11.2 0.0 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ribosomal_L19 PF01245.20 KXL47676.1 - 1.1e-12 47.8 0.1 2e-12 47.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 MFS_1 PF07690.16 KXL47678.1 - 1e-35 123.3 46.3 1e-35 123.3 46.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL47678.1 - 1.6e-05 24.0 18.6 1.6e-05 24.0 18.6 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter Opi1 PF08618.10 KXL47679.1 - 1.7e-30 106.6 5.7 2.6e-23 83.0 1.9 2.3 1 1 1 2 2 2 2 Transcription factor Opi1 ABC2_membrane PF01061.24 KXL47680.1 - 1.3e-77 260.0 58.7 2.6e-41 141.4 28.6 2.9 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KXL47680.1 - 2.3e-33 115.6 0.0 2.3e-15 57.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KXL47680.1 - 1.4e-25 89.0 9.8 1e-23 83.0 0.1 4.0 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KXL47680.1 - 6.8e-17 61.9 0.0 1.8e-16 60.5 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KXL47680.1 - 2.5e-06 28.0 0.2 0.011 16.1 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KXL47680.1 - 1.2e-05 25.3 0.0 0.14 12.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 KXL47680.1 - 0.0001 22.5 0.3 0.012 15.8 0.0 2.8 3 0 0 3 3 2 1 AAA domain ABC2_membrane_3 PF12698.7 KXL47680.1 - 0.00023 20.4 15.3 0.00023 20.4 15.3 3.2 2 1 1 3 3 3 1 ABC-2 family transporter protein AAA_18 PF13238.6 KXL47680.1 - 0.00039 21.0 0.1 0.025 15.1 0.0 2.7 3 0 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 KXL47680.1 - 0.00054 19.9 0.0 0.0048 16.8 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KXL47680.1 - 0.00064 19.4 0.2 0.011 15.4 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KXL47680.1 - 0.00085 19.0 0.3 0.012 15.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KXL47680.1 - 0.0062 16.8 0.0 0.11 12.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXL47680.1 - 0.011 15.4 0.3 2.5 7.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KXL47680.1 - 0.02 15.2 0.0 0.79 10.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain SMC_N PF02463.19 KXL47680.1 - 0.02 14.3 0.0 0.77 9.2 0.0 2.5 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain cobW PF02492.19 KXL47680.1 - 0.044 13.4 1.1 0.43 10.1 0.4 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 KXL47680.1 - 0.081 13.3 0.1 11 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KXL47680.1 - 0.088 12.7 0.6 4 7.3 0.2 2.3 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 KXL47680.1 - 0.16 12.4 0.0 29 5.1 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KXL47680.1 - 0.18 11.8 0.7 9.3 6.3 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.23 KXL47680.1 - 0.18 11.9 0.1 15 5.8 0.2 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 KXL47680.1 - 0.18 12.2 0.3 59 4.1 0.0 3.3 3 0 0 3 3 3 0 RNA helicase Serpentine_r_xa PF03383.15 KXL47680.1 - 0.31 11.0 6.1 0.85 9.6 0.4 2.9 2 1 1 3 3 2 0 Caenorhabditis serpentine receptor-like protein, class xa AAA_23 PF13476.6 KXL47680.1 - 5.5 7.4 5.6 0.59 10.6 0.1 2.2 3 0 0 3 3 1 0 AAA domain CAF1C_H4-bd PF12265.8 KXL47682.1 - 7.2e-23 80.6 0.1 2.4e-22 79.0 0.1 2.0 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KXL47682.1 - 2.7e-22 78.6 18.2 2.6e-05 24.9 1.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL47682.1 - 8.7e-05 22.7 0.2 0.92 9.8 0.0 4.0 2 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KXL47682.1 - 0.0072 14.7 0.0 0.04 12.2 0.0 1.9 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz GATase_5 PF13507.6 KXL47683.1 - 1.5e-100 335.6 0.0 2.2e-100 335.1 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 KXL47683.1 - 9.5e-36 123.3 0.5 8.2e-24 84.5 0.2 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 KXL47683.1 - 2.9e-33 114.3 0.0 5.1e-33 113.5 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 KXL47683.1 - 3.1e-23 82.1 0.1 6.8e-23 81.0 0.1 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 KXL47683.1 - 0.052 14.2 0.2 1.5 9.5 0.0 2.6 2 0 0 2 2 2 0 AIR synthase related protein, N-terminal domain Tau95_N PF17682.1 KXL47684.1 - 5e-33 114.0 0.0 1e-32 113.0 0.0 1.5 1 0 0 1 1 1 1 Tau95 Triple barrel domain Tau95 PF09734.9 KXL47684.1 - 3.6e-31 108.8 0.1 7.8e-31 107.7 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain B56 PF01603.20 KXL47685.1 - 2.4e-191 636.2 6.2 2.9e-191 635.9 6.2 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 KXL47685.1 - 0.0051 16.7 1.9 1.7 8.5 0.0 2.4 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal SOG2 PF10428.9 KXL47685.1 - 0.15 11.2 0.0 0.15 11.2 0.0 2.6 3 0 0 3 3 3 0 RAM signalling pathway protein ELO PF01151.18 KXL47687.1 - 1.8e-60 204.6 17.2 2.1e-60 204.3 17.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Orai-1 PF07856.12 KXL47687.1 - 0.92 9.2 6.3 0.17 11.5 0.9 2.0 1 1 1 2 2 2 0 Mediator of CRAC channel activity COX5A PF02284.16 KXL47689.1 - 2.1e-41 140.1 0.2 2.6e-41 139.8 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DUF488 PF04343.13 KXL47689.1 - 0.053 14.1 0.5 0.098 13.2 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function, DUF488 Ank_2 PF12796.7 KXL47690.1 - 1.8e-06 28.4 0.1 9.3e-06 26.1 0.0 2.1 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXL47690.1 - 2.4e-06 27.5 0.3 0.27 11.9 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KXL47690.1 - 1.6e-05 25.3 0.1 0.00026 21.5 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KXL47690.1 - 0.00037 20.8 0.1 0.16 12.5 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Metallophos_2 PF12850.7 KXL47692.1 - 6.5e-10 39.4 0.0 8.3e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Aminotran_5 PF00266.19 KXL47693.1 - 5.9e-31 107.7 0.0 7.8e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.19 KXL47693.1 - 0.0038 17.3 0.0 0.027 14.5 0.0 2.3 3 0 0 3 3 3 1 B12 binding domain V-SNARE_C PF12352.8 KXL47695.1 - 0.0025 18.0 4.0 0.013 15.7 0.4 2.7 2 1 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus LANC_like PF05147.13 KXL47696.1 - 3.9e-31 107.9 0.0 5.9e-31 107.3 0.0 1.3 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein Pec_lyase PF09492.10 KXL47696.1 - 0.048 13.0 0.0 0.15 11.3 0.0 1.6 1 1 0 1 1 1 0 Pectic acid lyase DUF5388 PF17363.2 KXL47696.1 - 0.15 12.2 0.2 0.46 10.7 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5388) Ribosomal_L11_N PF03946.14 KXL47698.1 - 6.5e-24 83.6 0.1 1.2e-23 82.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KXL47698.1 - 1.1e-15 57.9 0.5 1.8e-15 57.2 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Sec62 PF03839.16 KXL47699.1 - 9.6e-71 237.7 2.9 9.6e-71 237.7 2.9 1.9 2 0 0 2 2 2 1 Translocation protein Sec62 MPM1 PF17234.2 KXL47699.1 - 0.049 13.9 0.5 0.049 13.9 0.5 2.1 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 Tom5 PF10642.9 KXL47699.1 - 3.6 7.7 9.5 0.37 10.9 1.5 3.3 3 0 0 3 3 3 0 Mitochondrial import receptor subunit or translocase PEHE PF15275.6 KXL47699.1 - 5.6 7.6 9.7 6.7 7.4 1.8 2.5 2 0 0 2 2 2 0 PEHE domain TFIIA PF03153.13 KXL47699.1 - 7.2 6.5 17.2 0.47 10.4 10.1 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Zn_clus PF00172.18 KXL47700.1 - 1.7e-07 31.2 9.8 1.7e-07 31.2 9.8 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXL47700.1 - 8.8e-06 24.8 4.3 1.8e-05 23.7 4.3 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain PLA2_inh PF02988.15 KXL47700.1 - 0.025 15.2 1.9 0.035 14.8 0.7 1.9 2 0 0 2 2 2 0 Phospholipase A2 inhibitor GLTP PF08718.11 KXL47701.1 - 6.4e-48 162.8 0.0 8.3e-48 162.4 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) NUP PF06516.11 KXL47701.1 - 0.016 14.5 0.0 0.018 14.3 0.0 1.1 1 0 0 1 1 1 0 Purine nucleoside permease (NUP) Caerin_1 PF07440.12 KXL47701.1 - 0.1 12.7 0.3 0.17 12.0 0.3 1.4 1 0 0 1 1 1 0 Caerin 1 protein Peptidase_S24 PF00717.23 KXL47702.1 - 1.2e-06 28.4 0.1 5e-06 26.4 0.1 1.9 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KXL47702.1 - 3.8e-05 23.5 0.0 0.0032 17.2 0.0 2.4 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Sirohm_synth_C PF14823.6 KXL47703.1 - 1.8e-25 88.4 0.0 2.6e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal NAD_binding_7 PF13241.6 KXL47703.1 - 6.3e-25 87.6 0.0 9.3e-25 87.1 0.0 1.2 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 KXL47703.1 - 4.6e-12 45.2 0.0 8.9e-12 44.2 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.6 KXL47703.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Spermine_synth PF01564.17 KXL47703.1 - 0.2 11.0 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Spermine/spermidine synthase domain FYVE PF01363.21 KXL47704.1 - 3.5e-22 78.3 17.6 5e-17 61.8 3.7 3.0 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 KXL47704.1 - 1.6e-11 43.8 1.8 4.3e-11 42.4 1.8 1.8 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-AN1 PF01428.16 KXL47704.1 - 0.003 17.7 4.9 0.003 17.7 4.9 3.3 3 1 1 4 4 4 1 AN1-like Zinc finger zf-Di19 PF05605.12 KXL47704.1 - 0.022 15.1 5.1 0.039 14.2 0.0 2.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding IBR PF01485.21 KXL47704.1 - 0.1 12.8 11.7 0.59 10.4 2.6 3.2 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain zf-C2H2_4 PF13894.6 KXL47704.1 - 0.33 11.9 18.5 4.5 8.4 0.0 5.0 4 0 0 4 4 4 0 C2H2-type zinc finger Methyltransf_13 PF08421.11 KXL47704.1 - 1.1 9.5 0.0 1.1 9.5 0.0 3.7 5 0 0 5 5 5 0 Putative zinc binding domain zinc_ribbon_15 PF17032.5 KXL47704.1 - 1.2 10.0 10.5 6.6 7.6 1.1 3.5 4 0 0 4 4 4 0 zinc-ribbon family HypA PF01155.19 KXL47704.1 - 3.4 7.7 10.8 1.9 8.5 0.8 3.2 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-UBP PF02148.19 KXL47704.1 - 8.4 6.8 8.6 4.2 7.8 2.9 2.6 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Rieske PF00355.26 KXL47706.1 - 1.1e-16 60.5 0.0 1.4e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ring_hydroxyl_A PF00848.19 KXL47707.1 - 3.4e-22 79.5 1.0 1.1e-12 48.4 0.1 2.3 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Methyltransf_10 PF05971.12 KXL47708.1 - 2.1e-60 204.6 0.0 2.9e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 KXL47708.1 - 2.2e-06 27.4 0.0 4.3e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KXL47708.1 - 0.00029 20.7 0.0 0.00055 19.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXL47708.1 - 0.0008 18.9 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 KXL47708.1 - 0.00086 19.0 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 KXL47708.1 - 0.0038 17.9 0.0 0.016 15.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL47708.1 - 0.0049 17.5 0.0 0.015 15.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 KXL47708.1 - 0.016 15.0 0.0 0.054 13.2 0.0 1.8 2 0 0 2 2 2 0 Met-10+ like-protein N6_Mtase PF02384.16 KXL47708.1 - 0.18 11.1 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase SWIRM PF04433.17 KXL47709.1 - 1.7e-32 111.6 0.1 4.1e-32 110.4 0.1 1.7 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 KXL47709.1 - 4.1e-26 90.8 14.6 8.1e-26 89.8 14.6 1.5 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 KXL47709.1 - 1.9e-09 37.6 0.0 3.9e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXL47709.1 - 1.7e-05 25.0 0.1 3.8e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 KXL47709.1 - 0.022 14.6 5.7 1.9 8.4 0.1 2.3 2 0 0 2 2 2 0 Zinc finger, ZZ type CDC45 PF02724.14 KXL47709.1 - 8.2 4.6 10.4 13 3.9 10.4 1.2 1 0 0 1 1 1 0 CDC45-like protein SNF2_N PF00176.23 KXL47710.1 - 2.6e-67 227.0 0.1 4.1e-67 226.4 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXL47710.1 - 3.6e-16 59.5 0.0 1.5e-14 54.3 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL47710.1 - 3.7e-05 23.8 0.0 0.00012 22.1 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KXL47710.1 - 0.043 13.0 0.0 0.095 11.9 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Prok-RING_4 PF14447.6 KXL47710.1 - 0.062 13.2 1.6 0.55 10.1 0.1 2.8 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXL47710.1 - 0.15 12.0 4.5 0.4 10.7 4.5 1.8 1 1 0 1 1 1 0 zinc-RING finger domain Cys_rich_KTR PF14205.6 KXL47710.1 - 0.44 10.4 1.6 1.7 8.5 1.6 2.0 1 0 0 1 1 1 0 Cysteine-rich KTR Zn-ribbon_8 PF09723.10 KXL47710.1 - 0.49 10.5 8.4 0.8 9.9 5.6 2.5 2 0 0 2 2 2 0 Zinc ribbon domain PI3_PI4_kinase PF00454.27 KXL47711.1 - 6.8e-40 137.5 0.0 1.4e-39 136.4 0.0 1.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase GATA PF00320.27 KXL47712.1 - 5.9e-16 57.8 2.6 1.1e-15 56.9 2.6 1.5 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 KXL47712.1 - 0.01 15.3 0.5 0.017 14.6 0.5 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding DUF4686 PF15742.5 KXL47712.1 - 0.016 14.3 1.3 0.028 13.5 1.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) CENP-F_leu_zip PF10473.9 KXL47712.1 - 0.018 15.0 6.3 1.5 8.9 2.5 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 KXL47712.1 - 0.031 13.6 2.1 0.047 13.0 2.1 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF2353 PF09789.9 KXL47712.1 - 0.071 12.5 2.6 0.11 11.9 2.6 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Pox_A_type_inc PF04508.12 KXL47712.1 - 0.1 12.5 1.1 2.4 8.1 0.0 2.7 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Zn-ribbon_8 PF09723.10 KXL47712.1 - 0.11 12.6 0.2 0.21 11.7 0.2 1.4 1 0 0 1 1 1 0 Zinc ribbon domain DUF2387 PF09526.10 KXL47712.1 - 0.18 12.0 0.0 0.46 10.7 0.0 1.6 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) DivIC PF04977.15 KXL47712.1 - 0.23 11.2 2.0 1.1 9.1 1.0 2.2 2 0 0 2 2 2 0 Septum formation initiator Csm1_N PF18504.1 KXL47712.1 - 0.42 11.0 0.1 0.42 11.0 0.1 2.6 2 1 1 3 3 3 0 Csm1 N-terminal domain Atg14 PF10186.9 KXL47712.1 - 1.3 8.0 5.7 1.1 8.3 4.2 1.6 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Abhydrolase_3 PF07859.13 KXL47713.1 - 2e-06 27.9 0.0 2.8e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXL47713.1 - 3.7e-06 26.1 0.0 5.7e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family GPHH PF16905.5 KXL47713.1 - 0.0054 16.5 0.1 0.013 15.3 0.1 1.6 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated Say1_Mug180 PF10340.9 KXL47713.1 - 0.3 9.9 0.0 0.69 8.7 0.0 1.6 1 1 0 1 1 1 0 Steryl acetyl hydrolase Cupin_2 PF07883.11 KXL47714.1 - 7.1e-14 51.3 0.2 1.4e-08 34.3 0.0 2.6 3 0 0 3 3 3 2 Cupin domain Cupin_3 PF05899.12 KXL47714.1 - 0.00031 20.4 0.0 0.19 11.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 KXL47714.1 - 0.00063 19.7 0.0 0.17 11.8 0.0 2.3 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase FdtA PF05523.11 KXL47714.1 - 0.0022 17.7 0.1 0.0099 15.6 0.0 2.0 2 0 0 2 2 2 1 WxcM-like, C-terminal Cupin_1 PF00190.22 KXL47714.1 - 0.0059 16.2 0.1 0.82 9.3 0.0 2.5 2 0 0 2 2 2 1 Cupin ARD PF03079.14 KXL47714.1 - 0.017 15.3 0.0 3 8.0 0.0 2.4 2 0 0 2 2 2 0 ARD/ARD' family AraC_binding PF02311.19 KXL47714.1 - 0.031 14.2 0.1 0.065 13.1 0.1 1.5 1 0 0 1 1 1 0 AraC-like ligand binding domain EutQ PF06249.12 KXL47714.1 - 0.1 12.4 0.0 1.5 8.5 0.0 2.5 2 1 1 3 3 3 0 Ethanolamine utilisation protein EutQ Vac_ImportDeg PF09783.9 KXL47715.1 - 3.2e-28 98.6 0.0 2.6e-27 95.6 0.0 2.3 2 1 0 2 2 2 1 Vacuolar import and degradation protein MFS_1 PF07690.16 KXL47718.1 - 3.4e-41 141.4 25.7 3.4e-41 141.4 25.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL47718.1 - 6.1e-16 58.3 3.9 6.1e-16 58.3 3.9 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXL47718.1 - 0.0012 17.3 3.1 0.0019 16.7 3.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Mntp PF02659.15 KXL47718.1 - 0.003 17.3 0.1 0.003 17.3 0.1 3.1 4 0 0 4 4 4 1 Putative manganese efflux pump MFS_3 PF05977.13 KXL47718.1 - 0.0054 15.2 2.3 0.0077 14.7 2.3 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector adh_short_C2 PF13561.6 KXL47719.1 - 5.7e-62 209.3 1.5 6.6e-62 209.1 1.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL47719.1 - 2e-41 141.6 1.2 2.4e-41 141.4 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL47719.1 - 3.3e-13 50.0 0.9 4.8e-13 49.4 0.9 1.2 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.15 KXL47719.1 - 0.052 13.4 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 YjeF-related protein N-terminus CDH-cyt PF16010.5 KXL47721.1 - 1.2e-19 70.7 1.1 3.4e-19 69.3 1.1 1.7 1 1 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 KXL47721.1 - 1.3e-06 28.6 0.2 1.4e-05 25.3 0.1 2.2 2 0 0 2 2 2 1 DOMON domain DUF4987 PF16377.5 KXL47721.1 - 0.0083 16.3 1.0 0.018 15.2 0.0 2.0 2 1 0 2 2 2 1 Domain of unknown function Reo_sigmaC PF04582.12 KXL47721.1 - 0.031 14.6 0.1 0.055 13.7 0.1 1.5 1 1 0 1 1 1 0 Reovirus sigma C capsid protein C-terminal domain Pribosyltran PF00156.27 KXL47722.1 - 8.4e-16 57.9 0.0 9.9e-16 57.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KXL47722.1 - 0.003 17.0 0.0 0.0041 16.6 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 KXL47722.1 - 0.049 13.1 0.0 0.067 12.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase Acyl-CoA_dh_1 PF00441.24 KXL47723.1 - 1.1e-31 110.1 1.6 1.6e-31 109.5 1.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXL47723.1 - 9e-20 71.4 0.2 3.1e-19 69.7 0.0 2.0 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KXL47723.1 - 4e-17 62.2 0.0 8e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXL47723.1 - 4.4e-11 43.2 0.1 8.2e-11 42.3 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Glucosaminidase PF01832.20 KXL47723.1 - 0.095 13.2 0.0 0.21 12.1 0.0 1.8 2 0 0 2 2 2 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase DUF4863 PF16155.5 KXL47724.1 - 0.00058 19.7 0.1 0.0012 18.7 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4863) Lactamase_B PF00753.27 KXL47725.1 - 1.1e-06 28.8 2.2 4.6e-06 26.8 2.2 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXL47725.1 - 0.00023 20.7 0.0 0.00047 19.7 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain HHH_7 PF14635.6 KXL47726.1 - 0.035 14.5 0.0 0.069 13.5 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Melibiase_2 PF16499.5 KXL47727.1 - 1.3e-38 132.8 4.8 1.7e-38 132.4 4.8 1.2 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KXL47727.1 - 1.6e-09 37.7 0.1 3.2e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain CoA_transf_3 PF02515.17 KXL47728.1 - 3.1e-129 431.3 0.0 3.5e-129 431.1 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III HET PF06985.11 KXL47730.1 - 1.2e-05 25.7 0.6 0.0058 17.0 0.5 2.1 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HET PF06985.11 KXL47731.1 - 2e-08 34.7 0.7 2.4e-08 34.4 0.7 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) COQ9 PF08511.11 KXL47732.1 - 4.5e-29 100.0 0.2 6.6e-29 99.5 0.2 1.2 1 0 0 1 1 1 1 COQ9 Malic_M PF03949.15 KXL47733.1 - 5.6e-90 301.1 0.0 7.5e-90 300.7 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KXL47733.1 - 2.7e-58 196.8 0.0 5.1e-58 195.9 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Glyco_hydro_26 PF02156.15 KXL47735.1 - 0.00061 19.3 0.4 0.0011 18.5 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 FlgO PF17680.1 KXL47736.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 FlgO protein PAC4 PF16093.5 KXL47737.1 - 2.7e-19 69.1 0.0 3.7e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 N2227 PF07942.12 KXL47738.1 - 9.5e-95 316.9 0.0 1.2e-94 316.6 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.12 KXL47738.1 - 0.028 15.1 0.1 0.13 13.0 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 KXL47738.1 - 0.079 13.6 0.1 0.37 11.5 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 KXL47738.1 - 0.1 12.4 0.1 0.24 11.2 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain RabGAP-TBC PF00566.18 KXL47739.1 - 2.2e-37 128.8 0.1 2.2e-37 128.8 0.1 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF4407 PF14362.6 KXL47739.1 - 0.21 10.9 2.7 2 7.7 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) MFS_1 PF07690.16 KXL47741.1 - 1e-06 28.0 21.0 0.0015 17.6 9.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_transf_8 PF01501.20 KXL47743.1 - 6.6e-23 81.6 0.1 5.1e-22 78.7 0.1 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KXL47743.1 - 0.016 14.6 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Nucleotid_trans PF03407.16 KXL47743.1 - 0.067 13.2 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase adh_short PF00106.25 KXL47745.1 - 7.8e-31 107.0 0.0 3e-30 105.2 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL47745.1 - 1.9e-24 86.5 0.0 5.5e-24 85.0 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL47745.1 - 0.00019 21.4 0.0 0.00038 20.4 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL47745.1 - 0.012 15.0 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family PX PF00787.24 KXL47747.1 - 1.3e-14 54.2 0.0 2e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 PX domain Syntaxin-6_N PF09177.11 KXL47747.1 - 0.00018 22.0 0.7 0.00056 20.4 0.7 1.9 1 0 0 1 1 1 1 Syntaxin 6, N-terminal SbsC_C PF18058.1 KXL47747.1 - 0.092 13.0 1.0 0.2 11.9 1.0 1.5 1 0 0 1 1 1 0 SbsC C-terminal domain TIP120 PF08623.10 KXL47747.1 - 0.1 12.4 0.2 0.2 11.4 0.2 1.4 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) Radical_SAM PF04055.21 KXL47749.1 - 2.5e-15 57.3 0.1 6.4e-15 55.9 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily BATS PF06968.13 KXL47749.1 - 2e-07 31.0 0.6 2e-07 31.0 0.6 2.1 2 1 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain SET PF00856.28 KXL47750.1 - 5.6e-12 46.4 0.0 1.1e-10 42.2 0.0 2.4 1 1 0 1 1 1 1 SET domain TPR_2 PF07719.17 KXL47750.1 - 1.3e-05 24.9 7.1 0.00074 19.4 0.2 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXL47750.1 - 2.3e-05 24.0 5.0 0.017 14.9 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXL47750.1 - 0.00057 19.9 0.1 0.015 15.5 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KXL47750.1 - 0.073 12.4 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 MalT-like TPR region DUF2148 PF09918.9 KXL47750.1 - 0.079 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein containing a ferredoxin domain (DUF2148) Amidohydro_3 PF07969.11 KXL47752.1 - 1.2e-16 61.2 1.0 5.4e-10 39.3 0.0 3.2 3 0 0 3 3 3 3 Amidohydrolase family Amidohydro_1 PF01979.20 KXL47752.1 - 1.6e-12 47.4 0.4 7.4e-09 35.4 0.0 3.3 3 0 0 3 3 3 2 Amidohydrolase family Ribosomal_S3_C PF00189.20 KXL47753.1 - 4.8e-25 87.9 0.1 2.1e-24 85.8 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KXL47753.1 - 1.3e-09 37.7 0.0 2.4e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 KH domain PHD PF00628.29 KXL47754.1 - 6.8e-06 25.9 7.2 1.2e-05 25.1 7.2 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KXL47754.1 - 0.018 15.3 0.3 0.04 14.2 0.3 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KXL47754.1 - 0.031 14.4 0.2 0.062 13.5 0.2 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain ING PF12998.7 KXL47754.1 - 0.11 13.1 0.4 0.25 11.9 0.4 1.7 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding DDE_1 PF03184.19 KXL47755.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease Coilin_N PF15862.5 KXL47756.1 - 0.092 12.6 0.5 0.14 12.0 0.5 1.2 1 0 0 1 1 1 0 Coilin N-terminus DUF3328 PF11807.8 KXL47757.1 - 1.2e-45 156.0 0.2 1.3e-45 155.9 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) tRNA-synt_1b PF00579.25 KXL47759.1 - 1.1e-57 195.6 0.0 1.5e-57 195.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Nexin_C PF08628.12 KXL47761.1 - 5.1e-21 75.3 0.1 1.3e-20 74.1 0.1 1.7 1 0 0 1 1 1 1 Sorting nexin C terminal NAGLU PF05089.12 KXL47761.1 - 0.022 13.8 0.0 0.031 13.2 0.0 1.1 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain SOG2 PF10428.9 KXL47761.1 - 1.5 7.9 8.6 1.9 7.6 8.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Dscam_C PF12355.8 KXL47761.1 - 4.4 8.3 13.2 4.4 8.3 11.9 1.6 1 1 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal VID27 PF08553.10 KXL47766.1 - 6.8e-191 633.9 0.0 9.5e-191 633.4 0.0 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 KXL47766.1 - 7.9e-71 237.4 0.0 7.9e-71 237.4 0.0 2.8 2 0 0 2 2 2 1 VID27 N-terminal region VID27_PH PF17747.1 KXL47766.1 - 9.4e-46 154.6 4.3 9.4e-46 154.6 4.3 2.0 2 0 0 2 2 2 1 VID27 PH-like domain Sid-5 PF17204.3 KXL47767.1 - 0.067 13.4 0.1 0.075 13.2 0.1 1.1 1 0 0 1 1 1 0 Sid-5 family HET PF06985.11 KXL47768.1 - 1.4e-08 35.2 0.0 1.5e-08 35.1 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cir_N PF10197.9 KXL47770.1 - 7.3e-06 26.1 1.6 7.3e-06 26.1 1.6 3.4 4 0 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR RIH_assoc PF08454.11 KXL47771.1 - 0.043 13.7 0.5 0.13 12.2 0.5 1.8 1 1 0 1 1 1 0 RyR and IP3R Homology associated AAA PF00004.29 KXL47772.1 - 7.4e-51 172.0 0.0 1.5e-39 135.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXL47772.1 - 5.7e-12 46.3 0.1 0.00035 21.0 0.0 3.7 3 0 0 3 3 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 KXL47772.1 - 4.4e-11 42.4 0.0 1.4e-10 40.8 0.0 2.0 1 1 0 1 1 1 1 AAA+ lid domain CDC48_2 PF02933.17 KXL47772.1 - 4.9e-10 39.0 0.2 1e-08 34.8 0.1 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 KXL47772.1 - 1.7e-09 38.0 0.3 0.0011 19.3 0.0 4.3 2 2 3 5 5 4 2 AAA domain TIP49 PF06068.13 KXL47772.1 - 3.6e-08 33.0 0.0 0.0078 15.5 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain NACHT PF05729.12 KXL47772.1 - 1.7e-07 31.3 1.9 0.0093 15.9 0.3 3.7 3 1 0 3 3 2 1 NACHT domain AAA_14 PF13173.6 KXL47772.1 - 2.6e-07 30.7 0.0 0.0019 18.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 KXL47772.1 - 4e-07 29.9 0.7 0.049 13.4 0.1 3.6 4 1 1 5 5 4 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KXL47772.1 - 6e-07 29.7 0.4 8.4e-05 22.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KXL47772.1 - 8.5e-07 29.1 0.4 0.0018 18.2 0.0 3.0 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KXL47772.1 - 1.6e-06 28.3 0.0 0.075 13.2 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KXL47772.1 - 1.6e-06 28.0 0.0 0.014 15.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KXL47772.1 - 2.8e-06 26.9 0.1 0.005 16.3 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KXL47772.1 - 3.4e-06 27.6 0.0 0.013 16.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 KXL47772.1 - 6.6e-06 26.5 0.0 0.038 14.4 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Sigma54_activat PF00158.26 KXL47772.1 - 6.8e-06 25.9 0.0 0.071 12.8 0.0 2.9 2 0 0 2 2 2 2 Sigma-54 interaction domain CDC48_N PF02359.18 KXL47772.1 - 1.2e-05 25.3 0.0 3.7e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain ATPase PF06745.13 KXL47772.1 - 1.6e-05 24.3 0.3 0.013 14.9 0.1 2.4 2 0 0 2 2 2 2 KaiC ATPase_2 PF01637.18 KXL47772.1 - 2.7e-05 24.2 1.1 0.36 10.7 0.0 3.8 2 2 3 5 5 4 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KXL47772.1 - 8.9e-05 22.3 0.0 0.13 12.0 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein TsaE PF02367.17 KXL47772.1 - 9.7e-05 22.4 0.0 0.23 11.5 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KXL47772.1 - 0.0001 21.9 2.7 0.05 13.1 0.0 3.5 4 0 0 4 4 4 1 P-loop containing dynein motor region NB-ARC PF00931.22 KXL47772.1 - 0.00019 20.7 0.0 0.23 10.6 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_30 PF13604.6 KXL47772.1 - 0.00022 21.0 0.7 0.28 10.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 KXL47772.1 - 0.00035 21.1 3.8 0.028 14.9 0.1 2.9 3 0 0 3 3 2 1 ABC transporter AAA_28 PF13521.6 KXL47772.1 - 0.00042 20.6 0.0 0.21 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 KXL47772.1 - 0.00064 19.2 0.0 1.4 8.4 0.0 2.8 2 0 0 2 2 2 2 PhoH-like protein AAA_11 PF13086.6 KXL47772.1 - 0.0023 17.8 0.0 0.46 10.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KXL47772.1 - 0.003 17.2 0.3 2.1 7.9 0.0 3.2 4 0 0 4 4 3 1 AAA domain AAA_3 PF07726.11 KXL47772.1 - 0.0067 16.3 0.2 0.57 10.0 0.0 2.9 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KXL47772.1 - 0.0071 15.6 0.1 1 8.6 0.1 2.6 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KXL47772.1 - 0.012 15.9 0.6 0.69 10.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 KXL47772.1 - 0.017 15.5 0.0 6.2 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 KXL47772.1 - 0.019 14.0 0.0 0.45 9.6 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 TniB PF05621.11 KXL47772.1 - 0.021 14.3 1.0 4.9 6.5 0.0 3.7 3 1 0 3 3 3 0 Bacterial TniB protein PEPCK_GTP PF00821.18 KXL47772.1 - 0.028 13.3 0.0 0.051 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain Cytidylate_kin PF02224.18 KXL47772.1 - 0.033 13.9 2.1 9.5 5.9 1.5 3.0 2 1 0 2 2 2 0 Cytidylate kinase AAA_29 PF13555.6 KXL47772.1 - 0.048 13.4 0.1 4.1 7.2 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain ResIII PF04851.15 KXL47772.1 - 0.048 13.7 2.4 12 5.9 0.1 3.3 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit Vps4_C PF09336.10 KXL47772.1 - 0.076 13.0 0.0 0.32 11.0 0.0 2.1 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain AAA_23 PF13476.6 KXL47772.1 - 0.12 12.9 1.4 2.6 8.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 KXL47772.1 - 0.12 12.5 0.0 30 4.7 0.0 2.9 3 0 0 3 3 2 0 Sigma-54 interaction domain KxDL PF10241.9 KXL47773.1 - 8.1e-31 106.2 1.6 1.1e-30 105.8 1.6 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein Spc7 PF08317.11 KXL47773.1 - 0.039 12.8 0.4 0.045 12.6 0.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein muHD PF10291.9 KXL47774.1 - 1.3e-69 234.6 0.0 1.9e-69 234.0 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 KXL47774.1 - 4.5e-09 36.5 0.1 1.3e-08 35.0 0.0 1.9 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain BAR PF03114.18 KXL47774.1 - 0.00029 20.6 1.3 0.00044 20.0 1.3 1.2 1 0 0 1 1 1 1 BAR domain Laminin_II PF06009.12 KXL47774.1 - 0.077 13.0 1.6 0.17 11.9 1.6 1.5 1 0 0 1 1 1 0 Laminin Domain II VPS38 PF17649.1 KXL47774.1 - 0.21 10.4 2.1 0.31 9.9 2.1 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting 38 Exonuc_VII_L PF02601.15 KXL47774.1 - 0.31 10.6 4.9 0.52 9.8 4.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit GAS PF13851.6 KXL47774.1 - 5.7 6.2 9.1 17 4.7 9.1 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DHR10 PF18595.1 KXL47774.1 - 6.4 6.9 9.1 0.2 11.7 2.1 2.0 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain HSP20 PF00011.21 KXL47775.1 - 1.8e-19 69.8 0.5 2.9e-14 53.0 0.2 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KXL47775.1 - 1.1e-05 24.9 0.0 0.02 14.4 0.0 2.7 2 1 0 2 2 2 2 HSP20-like domain found in ArsA NFACT-C PF11923.8 KXL47776.1 - 2.1e-41 140.1 0.3 2.1e-41 140.1 0.3 3.9 4 0 0 4 4 4 1 NFACT protein C-terminal domain NFACT-R_1 PF05670.13 KXL47776.1 - 2.3e-33 115.1 0.0 6.6e-33 113.6 0.0 1.9 1 0 0 1 1 1 1 NFACT protein RNA binding domain FbpA PF05833.11 KXL47776.1 - 3.5e-29 101.9 11.9 3.5e-29 101.9 11.9 2.3 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) Serine_rich PF08824.10 KXL47776.1 - 0.039 13.9 0.4 0.098 12.7 0.4 1.7 1 0 0 1 1 1 0 Serine rich protein interaction domain DUF4446 PF14584.6 KXL47776.1 - 8.2 6.4 9.9 0.4 10.6 1.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) RTA1 PF04479.13 KXL47777.1 - 4.9e-51 173.3 11.1 1.8e-48 164.9 3.3 2.6 3 0 0 3 3 3 2 RTA1 like protein PAP2_C PF14360.6 KXL47777.1 - 0.3 11.6 0.1 0.3 11.6 0.1 3.9 3 1 1 4 4 4 0 PAP2 superfamily C-terminal DUF373 PF04123.13 KXL47777.1 - 0.82 9.0 7.5 1.2 8.5 7.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Fungal_trans_2 PF11951.8 KXL47778.1 - 2.1e-07 30.1 0.1 2.1e-07 30.1 0.1 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL47778.1 - 4.1e-07 30.0 11.5 6.6e-07 29.3 11.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain vATP-synt_AC39 PF01992.16 KXL47778.1 - 0.051 13.1 0.1 0.94 8.9 0.0 2.2 2 0 0 2 2 2 0 ATP synthase (C/AC39) subunit RasGAP PF00616.19 KXL47780.1 - 5e-56 189.7 0.0 1.5e-55 188.2 0.0 1.8 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KXL47780.1 - 2.3e-30 105.6 1.5 2.3e-30 105.6 1.5 2.4 3 0 0 3 3 3 1 RasGAP C-terminus Orthopox_F14 PF06076.12 KXL47780.1 - 0.24 11.7 1.3 1.2 9.4 0.1 2.8 4 0 0 4 4 4 0 Orthopoxvirus F14 protein COG5 PF10392.9 KXL47780.1 - 9.1 6.5 10.1 0.31 11.2 0.4 3.5 4 1 0 4 4 4 0 Golgi transport complex subunit 5 Mis14 PF08641.12 KXL47782.1 - 3.1e-19 69.6 2.9 3.1e-19 69.6 2.9 1.7 2 0 0 2 2 2 1 Kinetochore protein Mis14 like TSC22 PF01166.18 KXL47782.1 - 0.12 12.7 1.6 0.18 12.2 0.4 2.0 2 0 0 2 2 2 0 TSC-22/dip/bun family Fib_alpha PF08702.10 KXL47782.1 - 0.33 11.1 2.6 1.2 9.3 1.3 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Cep57_MT_bd PF06657.13 KXL47782.1 - 0.99 9.9 7.2 0.64 10.5 0.6 3.5 2 1 2 4 4 4 0 Centrosome microtubule-binding domain of Cep57 HSCB_C PF07743.13 KXL47782.1 - 1.7 9.2 8.9 1.4 9.4 2.7 3.3 2 1 2 4 4 4 0 HSCB C-terminal oligomerisation domain OmpH PF03938.14 KXL47782.1 - 2.8 8.3 8.1 6.5 7.1 8.1 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Glyco_transf_24 PF18404.1 KXL47784.1 - 6e-148 491.5 3.0 1.1e-147 490.7 3.0 1.4 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 KXL47784.1 - 4.7e-70 236.4 0.1 1.1e-68 232.0 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KXL47784.1 - 1.1e-47 162.4 0.2 2e-47 161.6 0.2 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KXL47784.1 - 3.8e-42 142.8 0.0 7.5e-42 141.9 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 KXL47784.1 - 5.2e-42 143.0 1.5 2.8e-41 140.6 0.4 2.7 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 KXL47784.1 - 6e-34 117.8 0.3 1.6e-33 116.4 0.1 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 KXL47784.1 - 0.0035 16.9 0.2 0.0067 16.0 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mhr1 PF12829.7 KXL47784.1 - 0.063 13.4 0.1 0.92 9.6 0.0 2.7 2 0 0 2 2 2 0 Transcriptional regulation of mitochondrial recombination KcnmB2_inactiv PF09303.10 KXL47784.1 - 0.2 11.5 0.3 0.61 9.9 0.3 1.8 1 0 0 1 1 1 0 KCNMB2, ball and chain domain Helicase_C_2 PF13307.6 KXL47785.1 - 3.7e-55 186.7 0.0 9.4e-55 185.4 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 KXL47785.1 - 9.1e-50 168.7 0.0 1.6e-49 167.9 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 KXL47785.1 - 0.00011 22.2 0.0 0.16 11.9 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 KXL47785.1 - 0.0023 17.7 0.0 0.27 11.0 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase HBB PF06777.11 KXL47785.1 - 0.0028 17.4 0.0 0.0065 16.2 0.0 1.6 1 0 0 1 1 1 1 Helical and beta-bridge domain AAA_22 PF13401.6 KXL47785.1 - 0.0081 16.4 0.1 3 8.1 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KXL47785.1 - 0.015 14.9 0.0 0.059 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain PspB PF06667.12 KXL47785.1 - 0.11 12.6 0.4 0.25 11.4 0.4 1.6 1 0 0 1 1 1 0 Phage shock protein B Vma12 PF11712.8 KXL47786.1 - 3.1e-42 143.9 0.0 4.2e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase SWIRM-assoc_3 PF16498.5 KXL47786.1 - 0.11 12.7 0.1 0.29 11.4 0.1 1.7 1 0 0 1 1 1 0 SWIRM-associated domain at the C-terminal polyprenyl_synt PF00348.17 KXL47787.1 - 3.2e-72 242.7 0.0 1e-71 241.0 0.0 1.8 2 0 0 2 2 2 1 Polyprenyl synthetase GatB_N PF02934.15 KXL47788.1 - 4.8e-94 314.8 0.0 6.3e-94 314.4 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KXL47788.1 - 6.3e-21 74.8 0.1 1e-20 74.1 0.1 1.3 1 0 0 1 1 1 1 GatB domain SSXT PF05030.12 KXL47788.1 - 0.018 14.7 0.0 0.041 13.5 0.0 1.5 1 0 0 1 1 1 0 SSXT protein (N-terminal region) NTP_transf_3 PF12804.7 KXL47788.1 - 0.044 14.1 0.2 0.45 10.9 0.1 2.6 2 1 0 2 2 2 0 MobA-like NTP transferase domain DUF3683 PF12447.8 KXL47788.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3683) zf-CCCH_4 PF18044.1 KXL47789.1 - 1.9e-12 46.7 8.7 3.1e-06 26.8 2.9 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 KXL47789.1 - 1e-08 34.9 8.7 0.00032 20.5 0.3 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KXL47789.1 - 1.7e-08 34.3 15.8 3.9e-06 26.7 1.2 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 KXL47789.1 - 0.00039 20.6 0.5 0.00071 19.8 0.5 1.3 1 0 0 1 1 1 1 Zinc-finger containing family Torus PF16131.5 KXL47789.1 - 0.0015 19.2 9.9 0.14 12.8 1.2 2.6 2 1 1 3 3 3 2 Torus domain zf-CCCH_2 PF14608.6 KXL47789.1 - 0.0024 18.3 13.6 0.0072 16.8 2.1 2.3 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger DFP PF04127.15 KXL47789.1 - 0.18 11.6 0.5 0.31 10.9 0.5 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Lustrin_cystein PF14625.6 KXL47789.1 - 2.3 8.7 6.9 0.35 11.3 1.2 2.2 1 1 1 2 2 2 0 Lustrin, cysteine-rich repeated domain Carboxyl_trans PF01039.22 KXL47790.1 - 5.5e-80 269.4 0.0 6.9e-80 269.1 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain JmjC PF02373.22 KXL47791.1 - 1.3e-09 38.5 0.1 3.4e-09 37.1 0.1 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 KXL47791.1 - 7.9e-08 32.1 8.0 7.9e-08 32.1 8.0 2.5 2 0 0 2 2 2 1 PHD-finger Cupin_8 PF13621.6 KXL47791.1 - 7.9e-07 29.0 0.1 3.5e-06 26.9 0.1 2.0 1 1 0 1 1 1 1 Cupin-like domain JHD PF17811.1 KXL47791.1 - 1e-05 26.0 0.7 1e-05 26.0 0.7 1.8 2 0 0 2 2 2 1 Jumonji helical domain PHD_2 PF13831.6 KXL47791.1 - 0.0023 17.5 2.9 0.0023 17.5 2.9 2.9 4 0 0 4 4 4 1 PHD-finger Zn_clus PF00172.18 KXL47791.1 - 4.6 7.4 34.2 0.15 12.2 4.2 3.9 3 1 1 4 4 4 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.22 KXL47792.1 - 2e-15 56.4 0.4 3.1e-15 55.7 0.1 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXL47792.1 - 0.0013 18.3 0.0 0.0015 18.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_127 PF07944.12 KXL47794.1 - 3.3e-124 415.3 0.0 3.9e-124 415.0 0.0 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Sugar_tr PF00083.24 KXL47795.1 - 1e-88 298.2 25.7 1.2e-88 298.0 25.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL47795.1 - 6.6e-39 133.8 36.0 2.7e-35 122.0 23.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily HTH_psq PF05225.16 KXL47796.1 - 0.099 12.4 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Pkinase PF00069.25 KXL47797.1 - 9.9e-42 143.1 0.0 1.8e-41 142.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL47797.1 - 3.8e-23 82.1 0.0 7.8e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Vac7 PF12751.7 KXL47799.1 - 1.2e-141 472.7 11.2 1.4e-141 472.4 11.2 1.1 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 SAGA-Tad1 PF12767.7 KXL47800.1 - 4.6e-53 180.4 0.0 5.8e-53 180.0 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit CN_hydrolase PF00795.22 KXL47801.1 - 1.8e-38 132.4 0.0 6.6e-38 130.5 0.0 1.8 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase 2H-phosphodiest PF08975.10 KXL47802.1 - 0.075 13.0 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1868) DUF2183 PF09949.9 KXL47803.1 - 1.8e-22 79.5 0.1 5e-22 78.1 0.1 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) CotJA PF11007.8 KXL47803.1 - 0.027 14.3 0.8 0.19 11.6 0.8 2.3 2 0 0 2 2 2 0 Spore coat associated protein JA (CotJA) Acetyltransf_1 PF00583.25 KXL47804.1 - 3.4e-10 40.2 0.0 4.3e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXL47804.1 - 5.8e-06 26.6 0.0 9.2e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXL47804.1 - 1.3e-05 25.1 0.0 2.2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KXL47804.1 - 6e-05 23.0 0.0 8.4e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXL47804.1 - 0.006 16.7 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AIM24 PF01987.17 KXL47805.1 - 3.2e-48 164.2 0.0 4.2e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 ABC_membrane PF00664.23 KXL47806.1 - 7.8e-38 130.7 10.3 1e-37 130.3 10.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KXL47806.1 - 1.1e-34 119.8 0.0 2.3e-34 118.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KXL47806.1 - 6e-06 25.9 0.0 0.0014 18.1 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KXL47806.1 - 0.00051 20.5 0.0 0.0013 19.1 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KXL47806.1 - 0.00067 19.6 0.3 0.0071 16.2 0.1 2.3 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KXL47806.1 - 0.00078 19.3 0.6 0.0024 17.7 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXL47806.1 - 0.0013 19.0 0.0 0.0059 16.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KXL47806.1 - 0.0047 17.0 0.0 0.041 14.0 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.29 KXL47806.1 - 0.006 17.0 0.0 0.046 14.2 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KXL47806.1 - 0.0075 16.0 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KXL47806.1 - 0.01 15.8 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_14 PF13173.6 KXL47806.1 - 0.015 15.4 0.0 0.081 13.0 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXL47806.1 - 0.015 15.0 0.1 0.039 13.7 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 KXL47806.1 - 0.025 14.5 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain G-alpha PF00503.20 KXL47806.1 - 0.028 13.6 0.0 0.054 12.7 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AAA_23 PF13476.6 KXL47806.1 - 0.03 14.8 0.0 0.065 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KXL47806.1 - 0.06 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 KXL47806.1 - 0.067 13.4 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KXL47806.1 - 0.068 12.7 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 KXL47806.1 - 0.073 11.9 0.0 1.7 7.3 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Cytidylate_kin PF02224.18 KXL47806.1 - 0.089 12.5 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase Zeta_toxin PF06414.12 KXL47806.1 - 0.093 12.0 0.0 0.31 10.3 0.0 1.9 1 0 0 1 1 1 0 Zeta toxin ATP-synt_ab PF00006.25 KXL47806.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.6 KXL47806.1 - 0.16 12.6 0.0 0.43 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain 2Fe-2S_thioredx PF01257.19 KXL47807.1 - 9e-62 207.2 0.1 1.2e-61 206.8 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Cu_amine_oxid PF01179.20 KXL47808.1 - 3.4e-144 480.8 0.0 4.5e-144 480.4 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KXL47808.1 - 5.2e-09 36.2 0.2 1.1e-08 35.2 0.2 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 KXL47808.1 - 0.0018 18.6 0.0 0.005 17.2 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain TMEM234 PF10639.9 KXL47808.1 - 0.17 12.0 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative transmembrane family 234 Fungal_trans_2 PF11951.8 KXL47809.1 - 2.9e-54 184.4 1.9 3.6e-54 184.0 1.9 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL47809.1 - 8.3e-09 35.4 11.2 1.3e-08 34.8 11.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.19 KXL47809.1 - 1.6 8.9 8.4 4.5 7.5 8.4 1.8 1 0 0 1 1 1 0 AT hook motif DUF3824 PF12868.7 KXL47811.1 - 4e-24 85.9 37.2 4e-24 85.9 37.2 9.9 4 3 6 10 10 10 4 Domain of unknwon function (DUF3824) Acyltransferase PF01553.21 KXL47813.1 - 1.8e-25 89.1 0.0 2.8e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KXL47813.1 - 2.9e-13 49.7 0.1 6.1e-13 48.7 0.1 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus SGP PF17228.2 KXL47815.1 - 0.41 11.5 5.5 0.91 10.4 5.5 1.7 1 0 0 1 1 1 0 Sulphur globule protein DUF3482 PF11981.8 KXL47815.1 - 0.58 9.5 4.7 0.76 9.1 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) CorA PF01544.18 KXL47816.1 - 1.1e-46 159.5 0.7 9.7e-25 87.5 1.0 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Cupin_2 PF07883.11 KXL47817.1 - 0.0018 17.9 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain RTA1 PF04479.13 KXL47818.1 - 4e-29 101.7 12.8 5.2e-29 101.3 12.8 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF2567 PF10821.8 KXL47818.1 - 0.2 11.8 5.7 0.12 12.4 2.5 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2567) SpoIIE PF07228.12 KXL47818.1 - 0.21 11.5 0.0 0.4 10.6 0.0 1.6 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) LCAT PF02450.15 KXL47819.1 - 3.7e-106 355.6 0.0 4.5e-106 355.3 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF1749 PF08538.10 KXL47819.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Acetyltransf_1 PF00583.25 KXL47820.1 - 1.2e-17 64.2 0.0 1.8e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXL47820.1 - 8.1e-11 42.0 0.0 1.3e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXL47820.1 - 2.1e-09 37.7 0.0 3.3e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXL47820.1 - 7.7e-09 35.4 0.0 1.2e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KXL47820.1 - 6.5e-08 33.3 0.0 8.5e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KXL47820.1 - 7.5e-05 22.4 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXL47820.1 - 0.00046 20.3 0.0 0.00085 19.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KXL47820.1 - 0.0051 17.0 0.0 0.0062 16.7 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 KXL47820.1 - 0.016 14.8 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_CG PF14542.6 KXL47820.1 - 0.029 14.5 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 KXL47820.1 - 0.12 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Polysacc_deac_1 PF01522.21 KXL47821.1 - 1.9e-18 66.5 0.0 3.2e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KXL47821.1 - 0.00063 19.5 0.2 0.0036 17.0 0.2 2.1 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 KXL47821.1 - 0.046 12.1 0.0 0.066 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) CPSase_L_D2 PF02786.17 KXL47822.1 - 1.3e-56 191.4 0.2 2.4e-56 190.6 0.2 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KXL47822.1 - 8.7e-33 112.7 0.0 2.9e-32 111.0 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KXL47822.1 - 7.4e-29 100.5 0.0 1.9e-28 99.2 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 KXL47822.1 - 1.7e-11 43.8 5.4 4.2e-11 42.5 4.0 2.4 1 1 1 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KXL47822.1 - 1.2e-09 38.0 0.0 2.6e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KXL47822.1 - 5.1e-07 29.4 0.3 3.4e-06 26.8 0.2 2.2 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KXL47822.1 - 4.5e-06 26.8 0.2 9.1e-06 25.8 0.2 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 KXL47822.1 - 0.0014 18.5 0.3 0.0014 18.5 0.3 2.3 3 0 0 3 3 3 1 Biotin-lipoyl like RnfC_N PF13375.6 KXL47822.1 - 0.0017 18.3 0.4 0.0038 17.2 0.4 1.5 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain DUF5017 PF16409.5 KXL47822.1 - 0.0087 15.6 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5017) DUF2118 PF09891.9 KXL47822.1 - 0.0098 15.9 0.2 0.025 14.5 0.2 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) ATPgrasp_ST PF14397.6 KXL47822.1 - 0.011 15.1 0.0 0.066 12.4 0.0 2.0 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp ATPgrasp_Ter PF15632.6 KXL47822.1 - 0.023 14.5 0.0 0.064 13.0 0.0 1.8 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.11 KXL47822.1 - 0.044 13.4 0.0 0.16 11.6 0.0 1.9 1 1 0 1 1 1 0 RimK-like ATP-grasp domain DUF639 PF04842.12 KXL47822.1 - 0.067 12.6 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) ATPgrasp_YheCD PF14398.6 KXL47822.1 - 0.069 12.4 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 YheC/D like ATP-grasp Sec23_trunk PF04811.15 KXL47823.1 - 2.8e-45 154.8 0.0 6.5e-44 150.3 0.0 2.2 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KXL47823.1 - 8.4e-23 80.2 0.0 1.7e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KXL47823.1 - 9.2e-18 64.8 0.1 1.9e-17 63.8 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KXL47823.1 - 1.3e-16 60.3 3.5 3.4e-16 59.0 3.5 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KXL47823.1 - 3.2e-07 30.2 0.0 8.3e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat SLS PF14611.6 KXL47823.1 - 0.2 11.5 0.0 0.4 10.5 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator DLH PF01738.18 KXL47824.1 - 2.7e-14 53.3 0.0 3.5e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KXL47824.1 - 0.079 12.6 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold AOX PF01786.17 KXL47826.1 - 2.2e-97 324.9 0.1 2.5e-97 324.6 0.1 1.0 1 0 0 1 1 1 1 Alternative oxidase Acylphosphatase PF00708.18 KXL47827.1 - 2.5e-20 72.7 0.1 2.9e-20 72.5 0.1 1.1 1 0 0 1 1 1 1 Acylphosphatase CH PF00307.31 KXL47828.1 - 1.9e-05 24.8 0.0 4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain KAR9 PF08580.10 KXL47829.1 - 3.9e-146 488.4 12.2 3.9e-146 488.4 12.2 1.7 1 1 1 2 2 2 1 Yeast cortical protein KAR9 PLU-1 PF08429.11 KXL47829.1 - 0.0034 16.6 2.8 0.68 9.1 1.3 2.7 2 1 0 2 2 2 2 PLU-1-like protein GP41 PF00517.17 KXL47829.1 - 0.23 11.3 0.9 0.45 10.4 0.9 1.4 1 0 0 1 1 1 0 Retroviral envelope protein Spectrin PF00435.21 KXL47829.1 - 1.9 9.0 9.9 2 9.0 0.2 3.6 4 0 0 4 4 4 0 Spectrin repeat Spore_III_AB PF09548.10 KXL47829.1 - 4 7.5 5.5 14 5.8 0.1 2.9 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Prefoldin PF02996.17 KXL47829.1 - 5.1 7.0 5.7 36 4.3 0.1 3.4 4 0 0 4 4 4 0 Prefoldin subunit Prefoldin_2 PF01920.20 KXL47829.1 - 8.1 6.4 8.2 2 8.4 0.3 3.4 4 0 0 4 4 4 0 Prefoldin subunit Fringe PF02434.16 KXL47831.1 - 0.00023 20.7 0.2 0.0031 17.0 0.2 2.2 1 1 0 1 1 1 1 Fringe-like PAN_3 PF08277.12 KXL47831.1 - 0.00092 19.0 0.2 0.002 17.9 0.2 1.5 1 0 0 1 1 1 1 PAN-like domain PAN_4 PF14295.6 KXL47831.1 - 0.0013 18.6 0.8 0.0033 17.3 0.8 1.7 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 KXL47831.1 - 0.035 14.1 0.3 0.079 12.9 0.3 1.5 1 0 0 1 1 1 0 PAN domain Kelch_5 PF13854.6 KXL47832.1 - 1e-16 60.5 7.7 1.6e-08 34.4 0.0 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 KXL47832.1 - 6.2e-07 29.6 15.4 0.012 15.9 0.2 5.4 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_4 PF13418.6 KXL47832.1 - 2.5e-05 24.2 13.4 0.058 13.4 0.1 6.1 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.6 KXL47832.1 - 0.00026 21.2 11.2 1.4 9.3 0.2 5.6 4 1 1 5 5 5 2 Kelch motif Kelch_2 PF07646.15 KXL47832.1 - 0.0032 17.4 3.5 1.5 8.9 0.3 4.3 4 1 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 KXL47832.1 - 0.0047 16.5 6.6 0.29 10.7 1.1 4.0 4 0 0 4 4 4 2 Kelch motif DMRT-like PF15791.5 KXL47832.1 - 0.21 12.0 1.6 1.4 9.4 0.2 2.6 2 0 0 2 2 2 0 Doublesex-and mab-3-related transcription factor C1 and C2 SKG6 PF08693.10 KXL47832.1 - 0.9 9.0 2.8 0.69 9.4 0.3 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain SpoIISB_antitox PF14185.6 KXL47833.1 - 0.2 11.6 0.0 0.4 10.6 0.0 1.4 1 0 0 1 1 1 0 Antitoxin SpoIISB, type II toxin-antitoxin system DUF948 PF06103.11 KXL47834.1 - 0.39 11.0 7.3 0.23 11.7 0.3 2.9 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Pkinase PF00069.25 KXL47835.1 - 9.1e-15 54.7 0.0 1.3e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL47835.1 - 2.8e-08 33.4 0.0 4.2e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXL47835.1 - 0.0031 16.9 0.1 0.0045 16.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KXL47835.1 - 0.022 14.4 0.3 0.032 13.8 0.3 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 KXL47835.1 - 0.051 13.5 0.1 0.074 13.0 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family HSBP1 PF06825.12 KXL47836.1 - 8.6e-05 22.3 0.0 0.64 9.9 0.0 2.6 2 0 0 2 2 2 2 Heat shock factor binding protein 1 Xrn1_D3 PF18194.1 KXL47836.1 - 0.14 12.2 0.0 0.43 10.7 0.0 1.7 2 0 0 2 2 2 0 Exoribonuclease 1 Domain-3 GMC_oxred_N PF00732.19 KXL47837.1 - 6.8e-78 262.0 0.0 1e-77 261.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXL47837.1 - 4.2e-36 124.6 0.0 1.4e-35 122.9 0.0 1.9 1 1 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KXL47837.1 - 0.00014 21.0 0.1 0.00022 20.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXL47837.1 - 0.0011 18.3 0.0 0.0021 17.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXL47837.1 - 0.0016 18.1 0.2 0.078 12.5 0.1 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXL47837.1 - 0.0022 17.1 0.2 0.86 8.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 KXL47837.1 - 0.03 14.9 0.7 0.1 13.2 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXL47837.1 - 0.046 13.7 0.2 0.28 11.2 0.0 2.4 2 1 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXL47837.1 - 0.065 13.5 0.1 0.17 12.2 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXL47837.1 - 0.07 12.4 0.2 0.15 11.3 0.1 1.5 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.14 KXL47837.1 - 0.11 11.3 0.1 0.16 10.7 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.22 KXL47837.1 - 0.26 10.3 0.1 1 8.4 0.1 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Ribosomal_S18 PF01084.20 KXL47838.1 - 2.1e-13 50.2 0.0 4.9e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S18 PPR_2 PF13041.6 KXL47839.1 - 4.3e-09 36.4 0.4 0.0024 18.0 0.0 5.0 7 0 0 7 7 7 2 PPR repeat family PPR_3 PF13812.6 KXL47839.1 - 3.7e-06 26.9 0.3 1.3 9.2 0.0 4.4 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_long PF17177.4 KXL47839.1 - 2.9e-05 23.6 0.0 0.001 18.5 0.0 3.3 3 1 1 4 4 4 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KXL47839.1 - 0.00018 21.6 0.4 0.29 11.5 0.0 5.4 7 0 0 7 7 7 1 PPR repeat Ribosomal_L27A PF00828.19 KXL47840.1 - 3.2e-21 76.3 0.0 4.8e-21 75.8 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A K_trans PF02705.16 KXL47841.1 - 2.1e-166 554.6 17.3 2.5e-166 554.3 17.3 1.0 1 0 0 1 1 1 1 K+ potassium transporter His_biosynth PF00977.21 KXL47842.1 - 1.3e-47 162.2 0.1 3.9e-47 160.7 0.1 1.8 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 KXL47842.1 - 1e-22 80.8 0.0 1.8e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 KXL47842.1 - 3e-10 40.3 0.0 1.1e-06 28.6 0.0 2.3 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 KXL47842.1 - 3.2e-05 23.6 0.0 0.00011 21.9 0.0 1.8 3 0 0 3 3 3 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 KXL47842.1 - 0.0022 17.8 0.0 0.0054 16.5 0.0 1.7 1 0 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 KXL47842.1 - 0.0035 17.2 0.0 0.02 14.7 0.0 2.2 2 0 0 2 2 2 1 DJ-1/PfpI family SOR_SNZ PF01680.17 KXL47842.1 - 0.06 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 SOR/SNZ family ThiG PF05690.14 KXL47842.1 - 0.14 11.4 0.1 0.33 10.2 0.1 1.5 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Dus PF01207.17 KXL47842.1 - 0.2 10.7 0.1 0.41 9.7 0.1 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) S4 PF01479.25 KXL47843.1 - 1.6e-12 46.9 0.0 2.5e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 KXL47843.1 - 2e-08 35.0 0.0 3e-08 34.5 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain DSBA PF01323.20 KXL47845.1 - 8.3e-39 133.4 0.0 9.4e-39 133.2 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 KXL47845.1 - 0.00014 22.1 0.1 0.00046 20.4 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.6 KXL47845.1 - 0.011 15.8 0.1 0.44 10.6 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_5 PF13743.6 KXL47845.1 - 0.061 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin ANAPC4_WD40 PF12894.7 KXL47846.1 - 0.0002 21.6 0.0 0.0018 18.5 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXL47846.1 - 0.51 11.3 6.2 18 6.4 0.1 4.6 5 0 0 5 5 5 0 WD domain, G-beta repeat Lipocalin_5 PF13924.6 KXL47847.1 - 2e-25 89.3 0.0 2.9e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 Lipocalin-like domain Thi4 PF01946.17 KXL47848.1 - 2.2e-110 367.5 0.0 2.7e-110 367.1 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KXL47848.1 - 1.4e-07 31.4 2.1 3.2e-06 27.0 1.8 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXL47848.1 - 2.5e-05 23.5 0.1 0.00026 20.2 0.3 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KXL47848.1 - 7.2e-05 22.9 0.4 0.00021 21.4 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXL47848.1 - 0.00058 19.2 0.0 0.00083 18.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXL47848.1 - 0.0012 18.9 0.5 0.0028 17.6 0.1 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KXL47848.1 - 0.013 14.6 3.4 0.069 12.2 1.2 2.6 2 1 1 3 3 3 0 FAD binding domain Pyr_redox_3 PF13738.6 KXL47848.1 - 0.032 13.5 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXL47848.1 - 0.035 13.4 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXL47848.1 - 0.051 12.8 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KXL47848.1 - 0.1 11.3 0.6 0.37 9.4 1.0 1.6 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.14 KXL47848.1 - 0.23 10.2 0.5 0.34 9.7 0.5 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Y_phosphatase3 PF13350.6 KXL47849.1 - 3.5e-54 184.2 0.0 3.9e-54 184.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KXL47849.1 - 5.6e-06 26.1 0.0 7.9e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KXL47849.1 - 1.9e-05 24.3 0.0 8e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 KXL47849.1 - 0.023 14.5 0.0 0.057 13.2 0.0 1.6 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Glyco_hydro_10 PF00331.20 KXL47850.1 - 6.6e-78 262.0 0.1 8e-78 261.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Sugar_tr PF00083.24 KXL47851.1 - 3.7e-66 223.9 29.1 4.3e-66 223.6 29.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL47851.1 - 1.9e-19 69.8 56.7 1e-14 54.3 34.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DDOST_48kD PF03345.14 KXL47852.1 - 8e-143 476.2 0.0 9.1e-143 476.0 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta CFEM PF05730.11 KXL47855.1 - 1e-10 41.5 7.4 1.9e-10 40.7 7.4 1.5 1 0 0 1 1 1 1 CFEM domain Sporozoite_P67 PF05642.11 KXL47855.1 - 0.19 9.8 11.6 0.22 9.6 11.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen zf-C2H2_8 PF15909.5 KXL47855.1 - 0.64 10.3 4.9 1.3 9.3 4.9 1.5 1 0 0 1 1 1 0 C2H2-type zinc ribbon Aerolysin PF01117.20 KXL47855.1 - 0.77 8.9 6.4 0.93 8.6 6.4 1.0 1 0 0 1 1 1 0 Aerolysin toxin DUF281 PF03436.13 KXL47855.1 - 6.7 7.2 11.1 0.43 11.0 2.7 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF281) Sugar_tr PF00083.24 KXL47856.1 - 4.8e-101 338.9 27.9 6e-101 338.5 27.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL47856.1 - 1.6e-23 83.2 57.4 1.3e-20 73.7 33.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 KXL47860.1 - 0.00034 19.7 0.0 0.0006 18.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DLIC PF05783.11 KXL47862.1 - 0.00018 20.5 17.2 0.013 14.3 0.1 4.9 6 0 0 6 6 6 3 Dynein light intermediate chain (DLIC) RIX1 PF08167.12 KXL47862.1 - 0.022 14.5 0.2 0.038 13.7 0.2 1.3 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis Adeno_terminal PF02459.15 KXL47862.1 - 0.073 11.5 0.3 0.23 9.8 0.0 1.8 2 1 0 2 2 2 0 Adenoviral DNA terminal protein EVC2_like PF12297.8 KXL47863.1 - 0.004 15.9 0.1 0.0093 14.7 0.0 1.5 2 0 0 2 2 2 1 Ellis van Creveld protein 2 like protein CYYR1 PF10873.8 KXL47863.1 - 0.0064 17.0 1.8 0.22 12.0 0.2 2.3 2 0 0 2 2 2 1 Cysteine and tyrosine-rich protein 1 Amnionless PF14828.6 KXL47863.1 - 0.018 13.9 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Amnionless SKG6 PF08693.10 KXL47863.1 - 0.059 12.8 4.0 0.096 12.1 4.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 KXL47863.1 - 1.2 9.0 4.2 2.2 8.1 4.2 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 FMO-like PF00743.19 KXL47864.1 - 4.8e-17 61.6 0.9 2.8e-16 59.1 0.2 2.1 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXL47864.1 - 5e-07 29.2 0.0 0.0013 17.9 0.0 3.7 3 1 1 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KXL47864.1 - 5.3e-07 29.2 0.0 3e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXL47864.1 - 2.3e-06 27.7 0.0 1.3e-05 25.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXL47864.1 - 4.9e-05 22.7 0.0 0.00041 19.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXL47864.1 - 0.00041 20.4 0.0 0.017 15.1 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Mqo PF06039.15 KXL47864.1 - 0.061 11.9 0.1 0.3 9.6 0.0 1.9 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) EFP_N PF08207.12 KXL47864.1 - 0.064 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain CNH PF00780.22 KXL47866.1 - 4.1e-69 233.2 0.0 6.3e-69 232.6 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 KXL47866.1 - 3.9e-32 112.0 0.1 6.2e-32 111.3 0.1 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 KXL47866.1 - 2e-12 47.4 0.0 3.5e-11 43.3 0.0 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 KXL47866.1 - 0.0066 16.3 0.0 0.4 10.5 0.1 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KXL47866.1 - 0.032 14.7 0.0 0.22 12.0 0.0 2.4 2 0 0 2 2 2 0 PH domain Nup160 PF11715.8 KXL47867.1 - 3.4e-90 303.2 0.0 4.9e-90 302.7 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Hira PF07569.11 KXL47868.1 - 1.7e-82 276.5 0.0 4.5e-82 275.1 0.0 1.8 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 KXL47868.1 - 5.5e-27 93.5 20.0 9.1e-05 23.2 0.0 8.7 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL47868.1 - 9.6e-15 54.7 0.0 0.0098 16.2 0.0 5.9 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 KXL47868.1 - 8.6e-09 35.0 0.3 1.8e-08 34.0 0.3 1.6 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 KXL47868.1 - 0.00016 21.5 1.0 0.014 15.3 0.2 3.8 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KXL47868.1 - 0.00019 20.5 0.3 0.091 11.7 0.0 3.9 4 0 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 KXL47868.1 - 0.048 11.6 0.2 1.1 7.2 0.0 2.4 3 0 0 3 3 3 0 IKI3 family CIA30 PF08547.12 KXL47869.1 - 1.8e-39 135.3 0.0 2.6e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) L_biotic_typeA PF04604.13 KXL47869.1 - 0.053 13.4 0.2 0.22 11.4 0.0 2.1 3 0 0 3 3 3 0 Type-A lantibiotic FAM60A PF15396.6 KXL47871.1 - 0.033 14.2 1.7 0.55 10.2 0.3 2.1 1 1 1 2 2 2 0 Protein Family FAM60A bZIP_Maf PF03131.17 KXL47871.1 - 0.041 14.4 2.0 0.069 13.7 2.0 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_1 PF00170.21 KXL47871.1 - 0.089 12.9 5.7 0.18 11.9 5.7 1.4 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 KXL47871.1 - 0.1 12.7 4.7 0.17 12.0 4.7 1.3 1 0 0 1 1 1 0 Basic region leucine zipper Pectinesterase PF01095.19 KXL47873.1 - 4.9e-46 156.8 3.7 6e-46 156.5 3.7 1.0 1 0 0 1 1 1 1 Pectinesterase Methyltransf_11 PF08241.12 KXL47875.1 - 1.9e-17 63.7 0.0 3.6e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL47875.1 - 5.5e-16 59.1 0.0 1.4e-15 57.7 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXL47875.1 - 4.8e-12 46.0 0.0 8.3e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL47875.1 - 9.1e-12 45.0 0.0 1.5e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL47875.1 - 5.7e-10 39.8 0.0 9.5e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXL47875.1 - 3.4e-07 29.8 0.0 5.7e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KXL47875.1 - 7.8e-07 28.7 0.0 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXL47875.1 - 3.1e-06 26.8 0.0 4.9e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KXL47875.1 - 0.00011 22.0 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 KXL47875.1 - 0.00013 21.6 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.13 KXL47875.1 - 0.0022 17.4 0.0 0.0031 17.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.14 KXL47875.1 - 0.0032 16.9 0.0 0.0052 16.2 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_2 PF00891.18 KXL47875.1 - 0.013 14.8 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain RrnaAD PF00398.20 KXL47875.1 - 0.018 14.1 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_8 PF05148.15 KXL47875.1 - 0.021 14.7 0.0 0.33 10.8 0.0 2.4 2 1 0 2 2 2 0 Hypothetical methyltransferase DUF3368 PF11848.8 KXL47875.1 - 0.037 13.8 0.0 0.27 11.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) Methyltransf_32 PF13679.6 KXL47875.1 - 0.14 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PXA PF02194.15 KXL47876.1 - 1.7e-47 161.7 0.4 7.6e-47 159.6 0.4 2.1 1 0 0 1 1 1 1 PXA domain DAO PF01266.24 KXL47876.1 - 7.1e-45 154.1 0.3 7.1e-45 154.1 0.3 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Nexin_C PF08628.12 KXL47876.1 - 6.2e-22 78.3 0.7 1.8e-21 76.8 0.1 2.2 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 KXL47876.1 - 5.2e-21 74.7 0.1 1.1e-20 73.8 0.1 1.5 1 0 0 1 1 1 1 PX domain RGS PF00615.19 KXL47876.1 - 2.6e-11 43.8 0.0 6.2e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain NAD_binding_8 PF13450.6 KXL47876.1 - 0.00048 20.3 0.5 0.0014 18.8 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXL47876.1 - 0.0005 19.4 0.0 0.0013 18.0 0.0 1.6 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KXL47876.1 - 0.027 14.4 0.3 1.6 8.7 0.2 2.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KXL47876.1 - 0.056 12.5 0.2 0.87 8.6 0.1 2.3 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 KXL47876.1 - 0.075 12.3 0.0 0.55 9.4 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase LprI PF07007.12 KXL47876.1 - 9.6 6.9 6.7 58 4.4 0.3 3.4 3 0 0 3 3 3 0 Lysozyme inhibitor LprI EHN PF06441.12 KXL47877.1 - 4.4e-34 117.1 0.1 4e-32 110.8 0.0 2.8 3 0 0 3 3 3 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KXL47877.1 - 1.5e-06 28.1 0.2 2.2e-05 24.2 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold tRNA-synt_2b PF00587.25 KXL47879.1 - 8.4e-41 139.9 0.0 1.4e-40 139.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KXL47879.1 - 6.8e-11 42.2 0.0 1.3e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain TOC159_MAD PF11886.8 KXL47879.1 - 0.15 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Translocase of chloroplast 159/132, membrane anchor domain HsbA PF12296.8 KXL47880.1 - 1.5e-21 77.1 6.6 1.5e-21 77.1 6.6 2.4 2 1 1 3 3 3 1 Hydrophobic surface binding protein A Sugar_tr PF00083.24 KXL47881.1 - 1.9e-88 297.3 15.2 2.2e-88 297.1 15.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL47881.1 - 1.8e-21 76.5 23.0 7.9e-14 51.3 13.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXL47881.1 - 0.00022 19.9 0.7 0.00022 19.9 0.7 3.4 4 0 0 4 4 4 2 MFS/sugar transport protein TRI12 PF06609.13 KXL47881.1 - 0.037 12.5 0.1 0.037 12.5 0.1 1.7 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Zn_clus PF00172.18 KXL47882.1 - 1.6e-09 37.7 8.1 2.8e-09 36.9 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PseudoU_synth_1 PF01416.20 KXL47885.1 - 2.6e-08 34.3 0.0 1.1e-06 29.0 0.0 2.9 2 1 0 2 2 2 1 tRNA pseudouridine synthase TFIIE-A_C PF11521.8 KXL47885.1 - 0.031 14.6 2.0 0.82 10.0 0.0 3.6 4 0 0 4 4 4 0 C-terminal general transcription factor TFIIE alpha CEL_III_C PF18054.1 KXL47885.1 - 0.031 14.3 0.3 0.055 13.5 0.3 1.4 1 0 0 1 1 1 0 CEL-III C-terminal WASH-7_mid PF14744.6 KXL47885.1 - 0.17 11.0 0.2 0.35 9.9 0.1 1.5 2 0 0 2 2 2 0 WASH complex subunit 7 MFS_1 PF07690.16 KXL47886.1 - 6e-33 114.2 35.2 6e-33 114.2 35.2 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL47886.1 - 1.6e-13 50.4 7.4 1.6e-13 50.4 7.4 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter PUA PF01472.20 KXL47886.1 - 0.054 13.5 0.0 0.096 12.7 0.0 1.3 1 0 0 1 1 1 0 PUA domain MFS_1 PF07690.16 KXL47887.1 - 5.8e-39 134.0 18.2 5.8e-39 134.0 18.2 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KXL47887.1 - 0.012 13.9 4.2 0.014 13.7 1.5 2.1 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MPC PF03650.13 KXL47887.1 - 0.18 12.0 2.5 1.6 8.9 0.2 2.7 2 0 0 2 2 2 0 Mitochondrial pyruvate carriers FMN_dh PF01070.18 KXL47888.1 - 3.4e-112 374.9 0.7 4.2e-112 374.6 0.7 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KXL47888.1 - 1.5e-19 69.9 0.0 1.8e-18 66.4 0.0 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KXL47888.1 - 4e-07 29.5 0.1 6.2e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KXL47888.1 - 9.5e-05 21.5 4.8 0.0003 19.9 2.5 2.6 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KXL47888.1 - 0.0022 17.3 0.1 2 7.6 0.0 2.5 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KXL47888.1 - 0.0099 15.4 0.2 0.2 11.1 0.1 2.3 2 0 0 2 2 2 1 Histidine biosynthesis protein Glu_syn_central PF04898.14 KXL47888.1 - 0.057 12.9 0.0 0.087 12.3 0.0 1.2 1 0 0 1 1 1 0 Glutamate synthase central domain Sugar_tr PF00083.24 KXL47889.1 - 9e-90 301.7 24.7 1.1e-89 301.4 24.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL47889.1 - 9.7e-24 83.9 33.6 6e-23 81.3 27.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 KXL47889.1 - 0.014 15.9 2.5 0.014 15.9 2.5 2.8 4 0 0 4 4 4 0 Phage holin family 2 MR_MLE_C PF13378.6 KXL47890.1 - 2.4e-55 187.5 0.1 3.8e-55 186.8 0.1 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like ApbA_C PF08546.11 KXL47890.1 - 9.6e-29 100.1 0.0 2e-28 99.1 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KXL47890.1 - 5.7e-26 91.0 0.0 1e-25 90.1 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA MR_MLE_N PF02746.16 KXL47890.1 - 1.4e-18 67.2 0.0 2.9e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain AAA_12 PF13087.6 KXL47891.1 - 8.8e-41 139.7 0.1 1.7e-40 138.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXL47891.1 - 6.1e-24 85.2 0.0 2.4e-23 83.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXL47891.1 - 3.1e-08 34.1 0.0 3.8e-06 27.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXL47891.1 - 1.4e-05 25.0 0.0 0.0093 15.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 KXL47891.1 - 3.2e-05 23.3 0.1 0.19 10.9 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.6 KXL47891.1 - 0.097 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain HTH_7 PF02796.15 KXL47891.1 - 0.22 11.6 1.5 2.1 8.5 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase Solute_trans_a PF03619.16 KXL47892.1 - 4.9e-55 186.9 8.2 5.9e-55 186.6 8.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha CAF1 PF04857.20 KXL47893.1 - 1.4e-78 264.3 0.0 1.7e-78 264.0 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.20 KXL47893.1 - 0.0022 17.7 0.0 0.0057 16.4 0.0 1.7 2 0 0 2 2 2 1 3'-5' exonuclease Pex26 PF07163.12 KXL47894.1 - 0.00045 19.6 1.8 0.5 9.6 0.3 2.7 2 1 1 3 3 3 2 Pex26 protein Selenoprotein_S PF06936.11 KXL47894.1 - 0.0049 16.7 4.0 0.01 15.6 4.0 1.5 1 0 0 1 1 1 1 Selenoprotein S (SelS) SRP-alpha_N PF04086.13 KXL47894.1 - 0.36 10.7 3.3 0.54 10.1 3.3 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SWIRM-assoc_2 PF16496.5 KXL47894.1 - 6.2 5.6 7.6 8.9 5.1 7.6 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal ThiF PF00899.21 KXL47895.1 - 7.2e-40 136.9 0.0 1e-39 136.4 0.0 1.1 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 KXL47895.1 - 0.0026 18.0 0.0 0.011 16.0 0.0 1.9 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KXL47895.1 - 0.011 16.0 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 KXL47895.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 KXL47895.1 - 0.16 11.5 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.22 KXL47895.1 - 0.36 9.9 0.6 0.51 9.4 0.6 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Lectin_leg-like PF03388.13 KXL47896.1 - 3.2e-68 229.5 0.0 3.9e-68 229.2 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 KXL47896.1 - 1.5e-07 31.6 0.1 2.1e-07 31.1 0.1 1.1 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 KXL47896.1 - 4.2e-06 26.5 0.0 0.019 14.5 0.0 2.1 2 0 0 2 2 2 2 Legume lectin domain Golgin_A5 PF09787.9 KXL47897.1 - 0.016 14.7 3.5 0.04 13.4 3.5 1.7 1 0 0 1 1 1 0 Golgin subfamily A member 5 CENP-Q PF13094.6 KXL47897.1 - 0.4 10.9 13.7 0.061 13.5 5.1 3.1 3 1 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit zf-CpG_bind_C PF12269.8 KXL47897.1 - 1.7 8.3 6.1 4.3 7.1 0.1 2.3 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain RRM_1 PF00076.22 KXL47898.1 - 6.4e-39 131.6 2.4 3.3e-12 46.0 0.0 4.8 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXL47898.1 - 1.6e-15 56.7 0.0 0.0062 16.4 0.0 4.3 4 0 0 4 4 4 4 Occluded RNA-recognition motif RRM PF10378.9 KXL47898.1 - 3.2e-09 36.3 5.6 3.2e-09 36.3 5.6 4.2 4 0 0 4 4 4 1 Putative RRM domain RRM_7 PF16367.5 KXL47898.1 - 7.6e-06 26.0 0.0 0.095 12.8 0.0 3.7 3 0 0 3 3 3 2 RNA recognition motif DUF4523 PF15023.6 KXL47898.1 - 0.00031 20.6 0.0 0.43 10.4 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) FtsH_ext PF06480.15 KXL47898.1 - 0.045 14.1 1.3 3.5 8.0 0.7 3.0 3 0 0 3 3 3 0 FtsH Extracellular Nup35_RRM_2 PF14605.6 KXL47898.1 - 0.094 12.7 0.0 41 4.3 0.0 3.2 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KXL47898.1 - 0.1 12.6 8.2 3.9 7.6 3.6 3.6 4 1 0 4 4 4 0 RNA binding motif RNA_bind PF08675.11 KXL47898.1 - 0.2 11.7 0.3 1.1 9.4 0.0 2.4 3 0 0 3 3 3 0 RNA binding domain PRAS PF15798.5 KXL47898.1 - 0.79 10.3 3.8 0.39 11.3 0.2 2.2 2 0 0 2 2 2 0 Proline-rich AKT1 substrate 1 Oxidored_FMN PF00724.20 KXL47899.1 - 5.5e-38 131.1 0.0 7.3e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FMN_dh PF01070.18 KXL47899.1 - 0.0099 14.9 0.0 0.03 13.3 0.0 1.6 1 1 0 2 2 2 1 FMN-dependent dehydrogenase WAC_Acf1_DNA_bd PF10537.9 KXL47900.1 - 5.9e-35 119.8 0.0 5.9e-35 119.8 0.0 2.0 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 KXL47900.1 - 7e-22 77.8 0.3 7e-22 77.8 0.3 2.5 2 0 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 KXL47900.1 - 3e-13 49.9 0.9 6.2e-13 48.9 0.9 1.6 1 0 0 1 1 1 1 DDT domain Choline_kinase PF01633.20 KXL47900.1 - 0.036 13.7 0.3 0.098 12.2 0.3 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase WHIM1 PF15612.6 KXL47900.1 - 0.053 13.1 0.4 0.33 10.6 0.0 2.6 3 0 0 3 3 3 0 WSTF, HB1, Itc1p, MBD9 motif 1 Nop53 PF07767.11 KXL47900.1 - 2.5 7.4 25.6 0.015 14.7 14.2 2.3 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) PEARLI-4 PF05278.12 KXL47900.1 - 7.3 6.1 9.2 22 4.5 9.2 1.7 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Alg6_Alg8 PF03155.15 KXL47901.1 - 1.5e-178 594.7 24.1 1.7e-178 594.5 24.1 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Glyco_hydro_47 PF01532.20 KXL47902.1 - 4.2e-180 599.5 0.1 5.1e-180 599.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 SCA7 PF08313.12 KXL47903.1 - 3.4e-31 107.0 1.3 3.4e-31 107.0 1.3 1.9 2 0 0 2 2 2 1 SCA7, zinc-binding domain Sgf11 PF08209.11 KXL47903.1 - 0.0054 16.3 1.8 0.0093 15.5 1.8 1.4 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) CDC45 PF02724.14 KXL47903.1 - 2.6 6.2 8.7 3.5 5.8 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein U79_P34 PF03064.16 KXL47903.1 - 7.3 5.9 11.0 12 5.2 11.0 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF4611 PF15387.6 KXL47903.1 - 9.5 6.5 14.6 0.17 12.1 5.9 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Acetyltransf_7 PF13508.7 KXL47904.1 - 2e-08 34.5 0.1 2.5e-08 34.2 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXL47904.1 - 2.1e-07 30.9 0.0 2.6e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXL47904.1 - 1.8e-06 28.2 0.0 2.6e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KXL47904.1 - 0.0025 17.7 0.0 0.0042 17.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein PanZ PF12568.8 KXL47904.1 - 0.073 12.8 0.0 0.092 12.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Telomere_reg-2 PF10193.9 KXL47905.1 - 0.0081 16.6 1.3 4 7.9 0.5 3.9 3 0 0 3 3 3 1 Telomere length regulation protein HEAT PF02985.22 KXL47905.1 - 0.019 15.2 0.0 3.3 8.2 0.0 4.2 3 0 0 3 3 3 0 HEAT repeat Methyltr_RsmB-F PF01189.17 KXL47906.1 - 1.8e-25 89.8 0.7 1e-23 84.0 0.7 2.3 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KXL47906.1 - 3.6e-05 23.9 0.0 6.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Gar1 PF04410.14 KXL47907.1 - 2e-37 128.3 0.0 2.4e-37 128.1 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region DNA_ligase_A_M PF01068.21 KXL47908.1 - 1.1e-50 172.1 0.1 8.6e-48 162.7 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KXL47908.1 - 7.3e-21 75.3 0.1 1.6e-20 74.1 0.1 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KXL47908.1 - 8.3e-21 74.5 0.2 1.5e-19 70.4 0.0 2.7 2 1 1 3 3 3 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.19 KXL47908.1 - 0.034 14.0 0.1 5 6.9 0.0 2.3 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain ANAPC4_WD40 PF12894.7 KXL47910.1 - 4.4e-06 26.9 0.0 0.0035 17.6 0.0 3.1 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXL47910.1 - 7.9e-05 23.4 9.6 0.33 11.9 0.2 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat Raffinose_syn PF05691.12 KXL47911.1 - 1.7e-53 181.6 2.8 4.5e-43 147.1 0.1 3.3 1 1 2 3 3 3 3 Raffinose synthase or seed imbibition protein Sip1 DUF2396 PF09654.10 KXL47911.1 - 0.083 13.0 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2396) Fungal_trans PF04082.18 KXL47913.1 - 8.6e-14 51.2 1.5 3.5e-13 49.2 1.5 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KXL47913.1 - 8.4e-08 32.3 14.1 0.00096 19.5 1.6 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXL47913.1 - 0.0063 17.3 12.9 0.56 11.2 4.9 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXL47913.1 - 0.022 15.2 2.6 0.022 15.2 2.6 2.5 3 0 0 3 3 3 0 Zinc-finger double domain zf-met PF12874.7 KXL47913.1 - 1.9 9.0 6.0 32 5.1 0.2 3.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Phosphodiest PF01663.22 KXL47914.1 - 1.7e-21 77.3 0.2 3e-21 76.4 0.2 1.4 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KXL47914.1 - 0.00054 19.4 0.0 2.5 7.4 0.0 3.4 2 1 1 3 3 3 2 Sulfatase Sugar_tr PF00083.24 KXL47917.1 - 4.4e-84 282.9 15.9 5.1e-84 282.7 15.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL47917.1 - 1.1e-17 64.1 22.5 1.1e-17 64.1 22.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_31 PF01055.26 KXL47919.1 - 2.2e-88 297.4 7.8 3e-88 296.9 7.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 KXL47919.1 - 0.00011 22.4 0.1 0.0005 20.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4968) DUF5110 PF17137.4 KXL47919.1 - 0.0024 18.1 0.0 0.0063 16.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Alpha-amylase PF00128.24 KXL47920.1 - 5.7e-58 197.1 0.0 7.8e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KXL47920.1 - 4.9e-24 84.4 0.0 1.5e-23 82.8 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) CBM_20 PF00686.19 KXL47920.1 - 8.5e-17 60.9 0.0 1.7e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Starch binding domain TPR_12 PF13424.6 KXL47921.1 - 9.8e-25 86.7 11.2 3.4e-13 49.7 2.5 2.3 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 KXL47921.1 - 5.8e-16 57.8 4.0 4.3e-10 39.1 0.4 3.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXL47921.1 - 8.9e-10 38.0 5.3 0.00048 19.8 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXL47921.1 - 5.6e-09 35.5 1.8 0.0034 17.5 0.4 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXL47921.1 - 1.1e-06 28.3 2.6 0.12 12.6 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KXL47921.1 - 4.6e-06 26.2 0.2 9.5e-05 21.9 0.2 1.9 1 1 0 1 1 1 1 MalT-like TPR region TPR_7 PF13176.6 KXL47921.1 - 6.4e-05 22.7 0.6 0.057 13.5 0.0 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXL47921.1 - 6.7e-05 23.4 0.0 0.16 12.9 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXL47921.1 - 0.00012 22.2 1.6 0.27 11.7 0.1 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXL47921.1 - 0.00077 19.1 4.2 1.2 8.8 0.3 3.5 3 0 0 3 3 3 1 TPR repeat TPR_21 PF09976.9 KXL47921.1 - 0.0013 18.4 0.1 0.44 10.2 0.0 2.4 1 1 2 3 3 3 2 Tetratricopeptide repeat-like domain TPR_16 PF13432.6 KXL47921.1 - 0.011 16.3 0.2 0.44 11.2 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF630 PF04783.12 KXL47921.1 - 0.021 15.0 0.1 0.53 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF630) PPR PF01535.20 KXL47921.1 - 0.079 13.2 0.1 4.9 7.6 0.0 2.6 2 1 0 2 2 2 0 PPR repeat Glyco_hydro_2_C PF02836.17 KXL47922.1 - 1.3e-102 343.0 0.1 1.8e-102 342.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 KXL47922.1 - 2.9e-64 217.0 0.0 4.6e-64 216.4 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 KXL47922.1 - 1.2e-40 139.2 0.0 4.3e-40 137.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 KXL47922.1 - 2.3e-21 76.0 0.0 1.3e-20 73.7 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 KXL47922.1 - 3e-12 47.2 1.5 5.6e-12 46.3 0.1 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Mito_carr PF00153.27 KXL47923.1 - 8.7e-14 51.2 0.0 9.1e-05 22.3 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Fer2 PF00111.27 KXL47924.1 - 1.6e-13 50.4 0.5 2.3e-13 49.9 0.5 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain TOM13 PF08219.11 KXL47925.1 - 7.1e-30 102.8 0.0 1.6e-29 101.7 0.0 1.5 1 0 0 1 1 1 1 Outer membrane protein TOM13 60KD_IMP PF02096.20 KXL47925.1 - 6.2e-17 62.0 0.1 8.6e-17 61.5 0.1 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Cu_amine_oxid PF01179.20 KXL47926.1 - 2.9e-154 513.9 0.0 3.7e-154 513.6 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KXL47926.1 - 9.6e-17 61.2 0.0 2e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KXL47926.1 - 1.1e-13 51.2 0.1 2e-13 50.4 0.1 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Aldedh PF00171.22 KXL47927.1 - 8.7e-180 598.1 0.2 9.9e-180 598.0 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SMBP PF16785.5 KXL47927.1 - 0.029 14.6 0.2 0.071 13.3 0.2 1.6 1 0 0 1 1 1 0 Small metal-binding protein 7TMR-DISM_7TM PF07695.11 KXL47928.1 - 0.00021 21.2 6.3 0.00021 21.2 6.3 2.4 2 1 1 3 3 3 1 7TM diverse intracellular signalling Fun_ATP-synt_8 PF05933.13 KXL47928.1 - 0.11 12.7 1.2 0.33 11.1 1.2 1.8 1 0 0 1 1 1 0 Fungal ATP synthase protein 8 (A6L) SEP PF08059.13 KXL47929.1 - 2.4e-25 88.9 0.0 5.3e-25 87.8 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 KXL47929.1 - 2.1e-14 53.5 0.1 3.8e-14 52.7 0.1 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 KXL47929.1 - 7.7e-10 38.4 0.0 1.4e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 KXL47929.1 - 0.00055 19.5 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 TAP C-terminal domain Glyco_hydro_28 PF00295.17 KXL47932.1 - 1.6e-23 83.3 4.0 2.1e-23 82.9 4.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 KXL47932.1 - 5.2e-07 29.7 2.9 5.2e-07 29.7 2.9 2.9 1 1 1 2 2 2 1 Pectate lyase superfamily protein SGP PF17228.2 KXL47932.1 - 8.1 7.4 7.5 0.94 10.4 0.1 2.7 3 0 0 3 3 3 0 Sulphur globule protein WW PF00397.26 KXL47936.1 - 0.00048 20.1 1.6 0.0013 18.8 1.6 1.8 1 0 0 1 1 1 1 WW domain WRW PF10206.9 KXL47936.1 - 0.34 11.3 4.1 0.3 11.5 2.0 1.9 2 0 0 2 2 2 0 Mitochondrial F1F0-ATP synthase, subunit f SPC22 PF04573.12 KXL47937.1 - 1.6e-40 138.4 0.5 7.3e-28 97.2 0.1 2.1 2 0 0 2 2 2 2 Signal peptidase subunit Peptidase_S15 PF02129.18 KXL47938.1 - 3.8e-33 115.2 0.1 2.3e-31 109.4 0.0 2.1 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 KXL47938.1 - 6.8e-23 81.8 0.0 2.2e-21 76.9 0.0 2.3 2 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 KXL47938.1 - 0.0037 16.6 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 FAD_binding_3 PF01494.19 KXL47939.1 - 3.1e-78 263.5 0.0 4.2e-78 263.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXL47939.1 - 0.0015 17.8 0.0 0.052 12.8 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXL47939.1 - 0.0035 16.6 0.0 0.021 14.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXL47939.1 - 0.018 14.3 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 KXL47939.1 - 0.032 14.4 0.0 0.098 12.9 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lactamase_B_3 PF13483.6 KXL47940.1 - 1.1e-08 35.1 0.0 7e-06 26.0 0.0 2.2 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 KXL47940.1 - 1.6e-07 31.1 0.0 2.8e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KXL47940.1 - 1.7e-06 28.2 0.0 2.5e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily MFS_1 PF07690.16 KXL47941.1 - 6.1e-26 91.2 46.5 1.3e-24 86.8 45.3 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXL47941.1 - 9.7e-23 80.4 24.9 1.4e-22 79.9 24.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TMEM43 PF07787.12 KXL47941.1 - 0.00067 19.1 0.8 0.00067 19.1 0.8 2.5 2 1 0 2 2 2 1 Transmembrane protein 43 adh_short PF00106.25 KXL47942.1 - 4.9e-42 143.6 0.0 6.7e-42 143.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL47942.1 - 1.1e-27 97.1 0.0 2.8e-27 95.8 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL47942.1 - 8.9e-07 29.0 0.0 1.3e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KXL47942.1 - 0.024 14.5 0.1 0.041 13.8 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KXL47942.1 - 0.12 13.0 0.2 0.22 12.1 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TRI12 PF06609.13 KXL47944.1 - 8e-45 153.4 22.0 8.8e-45 153.2 22.0 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KXL47944.1 - 5.7e-21 74.8 43.0 5.7e-21 74.8 43.0 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 KXL47945.1 - 5.5e-09 35.3 0.9 5.5e-09 35.3 0.9 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL47945.1 - 0.00021 21.4 10.2 0.00042 20.4 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSI_integrin PF17205.3 KXL47945.1 - 0.025 14.3 1.3 0.064 13.0 1.3 1.7 1 0 0 1 1 1 0 Integrin plexin domain Ephrin_rec_like PF07699.13 KXL47945.1 - 0.24 11.2 5.8 0.45 10.3 5.8 1.4 1 0 0 1 1 1 0 Putative ephrin-receptor like PhyH PF05721.13 KXL47946.1 - 1.2e-10 42.0 0.0 2.2e-10 41.1 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) bZIP_1 PF00170.21 KXL47947.1 - 4.6e-08 33.0 13.6 4.6e-08 33.0 13.6 2.6 1 1 1 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 KXL47947.1 - 1.4e-05 25.5 13.9 1.4e-05 25.5 13.9 3.0 3 1 1 4 4 4 1 bZIP Maf transcription factor bZIP_2 PF07716.15 KXL47947.1 - 2.2e-05 24.4 11.9 2.2e-05 24.4 11.9 3.0 3 0 0 3 3 3 1 Basic region leucine zipper Fmp27_WPPW PF10359.9 KXL47947.1 - 0.061 12.2 11.3 0.14 11.0 11.3 1.5 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Atg14 PF10186.9 KXL47947.1 - 2.2 7.3 15.8 4.4 6.3 15.8 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 COMP PF11598.8 KXL47947.1 - 2.7 8.5 5.9 0.45 11.0 1.1 2.2 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein Tho2 PF11262.8 KXL47947.1 - 3 7.0 10.4 1.7 7.8 8.3 1.5 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Prominin PF05478.11 KXL47947.1 - 5.9 4.7 7.3 9.1 4.1 7.3 1.2 1 0 0 1 1 1 0 Prominin Sel1 PF08238.12 KXL47948.1 - 6.4e-17 61.6 5.8 3.9e-05 24.2 0.0 3.5 3 0 0 3 3 3 3 Sel1 repeat TPR_6 PF13174.6 KXL47948.1 - 0.0057 17.2 0.9 15 6.5 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat Cutinase PF01083.22 KXL47949.1 - 3.3e-38 131.4 0.1 4.1e-38 131.1 0.1 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_8 PF06259.12 KXL47949.1 - 0.00013 21.7 0.2 0.0002 21.1 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase DUF676 PF05057.14 KXL47949.1 - 0.062 12.8 0.0 0.082 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) BSD PF03909.17 KXL47950.1 - 2.6e-17 62.5 0.6 6e-17 61.4 0.6 1.6 1 0 0 1 1 1 1 BSD domain Suf PF05843.14 KXL47950.1 - 0.45 10.5 2.6 0.78 9.7 2.6 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) HTH_psq PF05225.16 KXL47951.1 - 6.5e-05 22.6 1.6 9.9e-05 22.0 1.6 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.16 KXL47951.1 - 0.0003 20.7 0.6 0.00059 19.8 0.1 1.8 2 1 0 2 2 2 1 Tc5 transposase DNA-binding domain Iron_permease PF04120.12 KXL47954.1 - 4.2e-39 133.2 14.9 1.6e-18 66.7 0.2 4.2 3 1 1 4 4 4 4 Low affinity iron permease MgtE PF01769.16 KXL47954.1 - 6.6 7.1 11.6 4.3 7.7 0.2 3.5 4 0 0 4 4 4 0 Divalent cation transporter WD40 PF00400.32 KXL47955.1 - 2.9e-39 132.4 22.1 2e-08 34.7 0.1 11.3 12 0 0 12 12 12 7 WD domain, G-beta repeat Utp12 PF04003.12 KXL47955.1 - 1.8e-19 70.0 0.0 2.8e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KXL47955.1 - 2.9e-15 56.3 0.0 0.91 9.9 0.0 9.4 4 1 4 10 10 10 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXL47955.1 - 6.8e-06 25.3 1.0 2.9 6.8 0.0 5.7 4 2 2 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KXL47955.1 - 9.8e-06 25.6 0.0 0.37 10.6 0.0 4.7 5 2 2 7 7 7 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KXL47955.1 - 0.0011 17.8 1.4 0.69 8.5 0.0 3.4 4 2 1 5 5 5 2 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KXL47955.1 - 0.023 15.2 4.8 1.8 9.2 0.0 4.8 4 0 0 4 4 4 0 PQQ-like domain Septin PF00735.18 KXL47956.1 - 1.8e-113 378.5 0.2 2.8e-113 377.9 0.2 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KXL47956.1 - 2.5e-07 30.8 0.0 5.1e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXL47956.1 - 9.6e-06 25.6 0.6 4.6e-05 23.4 0.0 2.4 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 KXL47956.1 - 5.6e-05 22.8 2.6 0.00024 20.7 0.2 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KXL47956.1 - 0.00071 19.9 0.5 0.0026 18.0 0.0 2.1 2 1 0 2 2 2 1 AAA domain Pox_A32 PF04665.12 KXL47956.1 - 0.0029 17.1 0.0 0.0051 16.3 0.0 1.3 1 0 0 1 1 1 1 Poxvirus A32 protein AIG1 PF04548.16 KXL47956.1 - 0.0057 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Roc PF08477.13 KXL47956.1 - 0.007 16.6 0.1 0.015 15.5 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 KXL47956.1 - 0.01 14.9 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) FOXP-CC PF16159.5 KXL47956.1 - 0.011 16.3 1.5 0.032 14.8 1.0 2.1 1 1 0 1 1 1 0 FOXP coiled-coil domain AAA_24 PF13479.6 KXL47956.1 - 0.012 15.4 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXL47956.1 - 0.026 14.9 0.8 0.074 13.4 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 KXL47956.1 - 0.03 13.4 0.3 0.13 11.3 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein KAP_NTPase PF07693.14 KXL47956.1 - 0.035 13.3 0.0 0.052 12.8 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain Ras PF00071.22 KXL47956.1 - 0.059 13.0 0.4 0.17 11.5 0.4 1.8 1 1 0 1 1 1 0 Ras family NACHT PF05729.12 KXL47956.1 - 0.073 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KXL47956.1 - 0.097 13.2 0.1 0.31 11.6 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.26 KXL47956.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PduV-EutP PF10662.9 KXL47956.1 - 0.13 12.0 0.3 4.8 6.9 0.3 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 KXL47956.1 - 0.23 11.2 0.5 14 5.4 0.1 2.5 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 KXL47956.1 - 0.34 11.0 6.3 4.4 7.3 0.0 3.2 2 1 1 3 3 3 0 Dynamin family DUF1664 PF07889.12 KXL47956.1 - 0.34 11.0 4.4 0.26 11.3 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) AAA_11 PF13086.6 KXL47956.1 - 2.6 7.8 5.7 35 4.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Cep57_CLD_2 PF14197.6 KXL47956.1 - 3.3 7.9 8.1 1.1 9.4 4.0 2.1 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Myc-LZ PF02344.15 KXL47956.1 - 4.2 7.6 7.0 2.8 8.1 1.4 2.6 2 0 0 2 2 2 0 Myc leucine zipper domain DegS PF05384.11 KXL47956.1 - 5.7 6.4 12.7 1.2 8.6 6.4 2.6 2 1 1 3 3 3 0 Sensor protein DegS WD40 PF00400.32 KXL47957.1 - 7.6e-23 80.4 5.9 0.00022 22.0 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL47957.1 - 4.4e-08 33.3 0.7 0.43 10.9 0.0 5.4 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 KXL47957.1 - 0.0042 17.0 0.1 4.7 7.3 0.0 3.7 4 0 0 4 4 4 1 PQQ enzyme repeat WD40_like PF17005.5 KXL47957.1 - 0.0051 16.2 0.0 0.076 12.3 0.0 2.1 2 0 0 2 2 2 1 WD40-like domain eIF2A PF08662.11 KXL47957.1 - 0.01 15.7 0.0 4.7 7.0 0.0 3.0 2 2 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.6 KXL47957.1 - 0.066 13.7 2.7 7.9 7.1 0.2 4.2 4 0 0 4 4 4 0 PQQ-like domain TPR_2 PF07719.17 KXL47958.1 - 1.2e-05 25.1 2.8 0.5 10.6 0.8 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat UBA PF00627.31 KXL47958.1 - 0.0022 17.9 0.0 0.0044 16.9 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain DnaJ PF00226.31 KXL47958.1 - 0.013 15.6 0.0 0.044 13.9 0.0 1.9 1 0 0 1 1 1 0 DnaJ domain TPR_12 PF13424.6 KXL47958.1 - 0.04 14.2 1.3 54 4.2 0.4 3.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXL47958.1 - 0.073 12.9 0.5 21 5.2 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Sugar_tr PF00083.24 KXL47961.1 - 3.6e-96 322.8 25.8 4.2e-96 322.5 25.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL47961.1 - 4.6e-24 85.0 29.9 6.5e-24 84.5 29.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXL47961.1 - 0.011 14.2 10.2 0.0069 14.8 3.3 2.1 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_64 PF16483.5 KXL47962.1 - 4e-130 434.4 0.0 4.5e-130 434.2 0.0 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase CRCB PF02537.15 KXL47963.1 - 5.9e-33 113.0 17.6 4e-19 68.7 7.0 2.4 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) Fungal_trans PF04082.18 KXL47964.1 - 1e-28 100.1 1.2 1.8e-28 99.3 1.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL47964.1 - 1.4e-08 34.7 7.5 2.6e-08 33.8 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_114 PF03537.13 KXL47965.1 - 1.9e-77 259.7 0.1 2.2e-77 259.5 0.1 1.0 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Translin PF01997.16 KXL47966.1 - 1.1e-46 159.4 0.0 1.3e-46 159.2 0.0 1.0 1 0 0 1 1 1 1 Translin family GMP_synt_C PF00958.22 KXL47966.1 - 0.025 14.6 0.1 0.49 10.5 0.0 2.2 2 0 0 2 2 2 0 GMP synthase C terminal domain DUF1241 PF06840.11 KXL47966.1 - 0.13 11.9 0.7 2.9 7.5 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1241) NAD_binding_10 PF13460.6 KXL47967.1 - 3.8e-08 33.5 0.1 2.2e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KXL47967.1 - 2.1e-06 27.5 0.0 9.8e-05 22.0 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family ApbA PF02558.16 KXL47967.1 - 0.0083 15.8 0.1 0.013 15.1 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 KXL47967.1 - 0.0095 16.2 0.0 0.028 14.7 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain DUF749 PF05370.11 KXL47967.1 - 0.11 12.6 0.0 0.31 11.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF749) PglD_N PF17836.1 KXL47967.1 - 0.12 13.0 0.0 0.29 11.8 0.0 1.6 1 0 0 1 1 1 0 PglD N-terminal domain Homeodomain PF00046.29 KXL47968.1 - 4.2e-13 48.9 2.6 8.3e-13 48.0 2.6 1.5 1 0 0 1 1 1 1 Homeodomain Urb2 PF10441.9 KXL47969.1 - 2.2e-40 138.8 2.7 2.2e-40 138.8 2.7 4.7 5 0 0 5 5 5 2 Urb2/Npa2 family MpPF26 PF07666.11 KXL47969.1 - 0.052 13.7 0.1 0.17 12.0 0.1 1.9 1 0 0 1 1 1 0 M penetrans paralogue family 26 COPIIcoated_ERV PF07970.12 KXL47970.1 - 1.2e-35 123.4 0.2 2.1e-35 122.6 0.2 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KXL47970.1 - 5.1e-26 90.9 0.0 1.1e-25 89.8 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) MFS_1 PF07690.16 KXL47971.1 - 8.1e-26 90.8 27.5 1.2e-25 90.2 27.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXL47971.1 - 0.0001 20.9 3.2 0.0001 20.9 3.2 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Methyltransf_2 PF00891.18 KXL47972.1 - 8.1e-24 84.1 0.2 2.8e-23 82.3 0.2 1.7 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 KXL47972.1 - 0.011 16.5 0.0 0.069 13.9 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain DAO PF01266.24 KXL47973.1 - 1.6e-24 87.2 0.0 1e-22 81.2 0.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXL47973.1 - 1.3e-05 24.6 0.0 0.0052 16.1 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXL47973.1 - 8.3e-05 23.1 0.1 0.14 12.7 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXL47973.1 - 0.0016 18.5 0.0 0.0061 16.6 0.1 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KXL47973.1 - 0.0035 16.5 0.1 0.18 10.9 0.1 2.2 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXL47973.1 - 0.014 15.6 0.1 0.031 14.5 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXL47973.1 - 0.044 12.5 0.1 0.54 8.9 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein DUF3431 PF11913.8 KXL47974.1 - 2.5e-85 285.7 0.2 3.1e-85 285.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Med13_C PF06333.12 KXL47975.1 - 4.2e-71 239.9 0.0 5.1e-71 239.6 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal domain MID_MedPIWI PF18296.1 KXL47975.1 - 1.1e-05 25.3 0.1 2.1e-05 24.5 0.0 1.5 2 0 0 2 2 2 1 MID domain of medPIWI RPN7 PF10602.9 KXL47976.1 - 2.4e-54 183.7 0.6 2.4e-54 183.7 0.6 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 KXL47976.1 - 3.2e-14 53.3 0.0 8.9e-14 51.9 0.0 1.8 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 KXL47976.1 - 0.023 14.8 1.3 0.071 13.2 1.3 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXL47976.1 - 0.32 11.7 4.8 0.13 13.0 1.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Med30 PF11315.8 KXL47976.1 - 2.1 8.5 4.7 1 9.5 1.2 2.0 2 0 0 2 2 2 0 Mediator complex subunit 30 Pox_MCEL PF03291.16 KXL47977.1 - 6.9e-73 245.6 0.0 1.1e-49 169.3 0.0 2.1 2 0 0 2 2 2 2 mRNA capping enzyme Methyltransf_25 PF13649.6 KXL47977.1 - 2.8e-09 37.6 0.0 0.0001 22.9 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KXL47977.1 - 3.2e-09 37.4 0.0 1.7e-08 35.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXL47977.1 - 3.9e-06 26.8 0.0 7.4e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL47977.1 - 9.4e-06 26.2 0.0 0.24 12.1 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KXL47977.1 - 1.2e-05 25.2 0.0 0.0001 22.1 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain MID_MedPIWI PF18296.1 KXL47978.1 - 1.1e-11 45.1 0.0 2e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 MID domain of medPIWI Aa_trans PF01490.18 KXL47979.1 - 1.2e-50 172.4 39.9 1.4e-50 172.2 39.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Amidohydro_1 PF01979.20 KXL47980.1 - 1.9e-44 152.4 0.0 3.4e-44 151.6 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXL47980.1 - 0.00033 20.3 0.0 0.038 13.4 0.0 2.6 3 0 0 3 3 3 2 Amidohydrolase family NUC153 PF08159.12 KXL47981.1 - 1e-10 41.2 1.6 2.6e-10 39.9 1.6 1.7 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 KXL47981.1 - 0.0025 18.6 0.2 15 6.7 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat Med13_N PF11597.8 KXL47982.1 - 4.7e-20 72.2 0.0 3.4e-19 69.4 0.0 2.1 1 1 0 1 1 1 1 Mediator complex subunit 13 N-terminal Cep57_MT_bd PF06657.13 KXL47983.1 - 1.7e-26 92.5 2.2 1.7e-26 92.5 2.2 5.3 5 0 0 5 5 5 2 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.6 KXL47983.1 - 3.7e-15 55.7 1.3 3.7e-15 55.7 1.3 5.4 4 3 1 5 5 5 1 Centrosome localisation domain of PPC89 Trimer_CC PF08954.11 KXL47983.1 - 0.015 14.8 2.1 0.081 12.5 0.5 3.2 2 0 0 2 2 2 0 Trimerisation motif Cnn_1N PF07989.11 KXL47983.1 - 0.016 15.3 1.1 0.016 15.3 1.1 5.9 4 1 2 6 6 6 0 Centrosomin N-terminal motif 1 NAPRTase_C PF17956.1 KXL47983.1 - 1.2 9.6 5.3 1 9.8 0.7 2.8 2 0 0 2 2 2 0 Nicotinate phosphoribosyltransferase C-terminal domain AA_permease_2 PF13520.6 KXL47984.1 - 5.1e-43 147.5 46.9 6.5e-43 147.1 46.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXL47984.1 - 8.1e-20 70.9 37.8 1.1e-19 70.4 37.8 1.1 1 0 0 1 1 1 1 Amino acid permease SID-1_RNA_chan PF13965.6 KXL47984.1 - 0.033 12.6 2.6 0.072 11.5 2.6 1.5 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 zf-C3HC PF07967.13 KXL47985.1 - 1.5e-35 122.2 4.5 2.6e-28 98.7 1.1 2.5 2 1 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 KXL47985.1 - 1.7e-19 69.8 1.5 1.3e-17 63.7 0.2 2.8 2 1 0 2 2 2 1 Rsm1-like Radial_spoke PF04712.12 KXL47985.1 - 1.3 7.9 8.1 0.097 11.6 2.4 1.8 2 0 0 2 2 2 0 Radial spokehead-like protein FAM176 PF14851.6 KXL47985.1 - 1.8 8.3 11.1 0.37 10.4 2.4 2.4 2 0 0 2 2 2 0 FAM176 family CENP-B_dimeris PF09026.10 KXL47985.1 - 2.5 8.5 13.6 0.074 13.4 6.3 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 KXL47985.1 - 2.7 8.4 9.6 20 5.6 0.3 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Voldacs PF03517.13 KXL47985.1 - 6.6 6.8 9.8 3.5 7.7 3.1 2.5 2 1 0 2 2 2 0 Regulator of volume decrease after cellular swelling Tom22 PF04281.13 KXL47985.1 - 8.7 6.1 10.0 0.71 9.7 2.7 2.6 3 0 0 3 3 3 0 Mitochondrial import receptor subunit Tom22 Fungal_trans PF04082.18 KXL47986.1 - 1.1e-10 41.0 0.0 1.8e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL47986.1 - 6.5e-09 35.8 11.4 1.1e-08 35.0 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NTP_transferase PF00483.23 KXL47987.1 - 2.8e-32 112.3 0.0 4e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KXL47987.1 - 2.8e-11 42.7 6.7 2.3e-06 27.1 0.0 3.5 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KXL47987.1 - 1.1e-08 35.6 0.0 1.8e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 KXL47987.1 - 0.039 13.7 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF2968 PF11180.8 KXL47987.1 - 0.039 13.6 0.1 0.071 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Hexapep_2 PF14602.6 KXL47987.1 - 0.52 10.1 1.9 15 5.5 0.0 3.2 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase Dynamin_N PF00350.23 KXL47988.1 - 3.6e-21 75.9 0.0 1.6e-20 73.9 0.0 2.2 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 KXL47988.1 - 1.2e-17 64.1 0.0 3.6e-12 46.1 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 KXL47988.1 - 6.2e-05 23.0 0.4 0.0023 18.0 0.1 3.3 3 1 0 3 3 3 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KXL47988.1 - 0.0026 18.2 0.0 0.032 14.6 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 KXL47988.1 - 0.0039 17.1 0.0 0.16 11.9 0.0 3.2 3 1 1 4 4 4 1 RsgA GTPase GED PF02212.18 KXL47988.1 - 0.0059 16.7 2.1 0.0066 16.6 0.5 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain ABC_tran PF00005.27 KXL47988.1 - 0.009 16.5 0.0 0.036 14.6 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 KXL47988.1 - 0.015 15.1 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 KXL47988.1 - 0.019 15.1 0.0 0.23 11.7 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 KXL47988.1 - 0.046 14.2 1.5 0.12 12.8 0.0 2.4 3 0 0 3 3 3 0 AAA domain FeoB_N PF02421.18 KXL47988.1 - 0.093 12.2 0.1 13 5.3 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_5 PF07728.14 KXL47988.1 - 0.15 12.0 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) VIT1 PF01988.19 KXL47988.1 - 0.17 11.7 0.1 0.41 10.5 0.1 1.6 1 0 0 1 1 1 0 VIT family Putative_PNPOx PF01243.20 KXL47989.1 - 2.1e-08 34.3 0.0 2.2e-05 24.6 0.0 2.8 2 1 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase ADH_zinc_N PF00107.26 KXL47990.1 - 8.7e-22 77.5 1.4 1.4e-21 76.8 1.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXL47990.1 - 1.2e-20 73.4 0.5 2.8e-20 72.2 0.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXL47990.1 - 0.0017 19.4 0.0 0.0032 18.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KXL47990.1 - 0.014 14.8 0.6 0.025 14.0 0.4 1.5 1 1 0 1 1 1 0 short chain dehydrogenase Glu_dehyd_C PF16912.5 KXL47990.1 - 0.019 14.5 0.4 0.027 13.9 0.4 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Epimerase PF01370.21 KXL47990.1 - 0.023 14.2 0.2 0.033 13.6 0.2 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family AlaDh_PNT_C PF01262.21 KXL47990.1 - 0.027 13.8 0.8 0.041 13.2 0.8 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain BTB PF00651.31 KXL47992.1 - 0.0018 18.5 0.0 0.0033 17.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain COX15-CtaA PF02628.15 KXL47993.1 - 3.9e-109 364.6 13.8 4.6e-109 364.4 13.8 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein MFS_1 PF07690.16 KXL47995.1 - 2.3e-10 39.9 35.5 2.3e-10 39.9 35.5 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Smr PF01713.21 KXL47996.1 - 0.00039 20.7 0.0 0.0012 19.1 0.0 1.9 1 0 0 1 1 1 1 Smr domain CUE PF02845.16 KXL47996.1 - 0.0017 18.0 0.0 0.0068 16.1 0.0 2.1 2 0 0 2 2 2 1 CUE domain UBA_4 PF14555.6 KXL47996.1 - 0.0041 16.9 0.1 0.11 12.3 0.0 2.6 3 0 0 3 3 3 1 UBA-like domain DUF1296 PF06972.11 KXL47996.1 - 0.089 12.9 0.0 2 8.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1296) KCH PF16944.5 KXL47997.1 - 6.5e-97 324.2 10.8 7.7e-97 324.0 10.8 1.0 1 0 0 1 1 1 1 Fungal potassium channel ECH_1 PF00378.20 KXL47998.1 - 3.6e-07 29.8 0.0 3.7e-06 26.4 0.0 2.2 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Dabb PF07876.12 KXL47999.1 - 2.6e-16 60.0 0.0 2.8e-16 59.9 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Sugar_tr PF00083.24 KXL48000.1 - 3e-79 267.0 20.4 3.4e-79 266.8 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL48000.1 - 6.5e-11 41.7 36.4 8.9e-11 41.3 33.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXL48000.1 - 0.0097 14.8 13.3 0.022 13.6 6.4 2.2 2 0 0 2 2 2 2 MFS_1 like family MFS_1 PF07690.16 KXL48003.1 - 1.1e-14 54.2 2.9 1.3e-14 53.9 2.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXL48003.1 - 0.0021 17.4 0.1 0.003 16.9 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB INTAP PF16617.5 KXL48005.1 - 0.00056 20.2 1.7 0.0012 19.1 1.7 1.7 1 0 0 1 1 1 1 Intersectin and clathrin adaptor AP2 binding region SLT PF01464.20 KXL48005.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Transglycosylase SLT domain AOC_like PF18678.1 KXL48005.1 - 0.52 9.9 2.7 2 8.1 0.1 2.6 3 0 0 3 3 3 0 Allene oxide cyclase barrel like domain AAT PF03417.16 KXL48006.1 - 2.1e-07 30.9 0.0 9.2e-07 28.8 0.0 2.0 1 1 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Glyoxalase PF00903.25 KXL48007.1 - 7.2e-38 129.7 0.7 3.6e-18 66.0 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KXL48007.1 - 1.3e-17 64.0 0.4 1.5e-06 28.4 0.0 4.9 2 2 3 5 5 5 5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KXL48007.1 - 1.8e-08 34.7 0.0 0.0037 17.4 0.0 3.2 1 1 2 3 3 3 3 Glyoxalase-like domain Glyoxalase_6 PF18029.1 KXL48007.1 - 3.7e-08 34.1 0.0 0.00054 20.7 0.0 2.7 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KXL48007.1 - 4.1e-05 23.5 2.1 0.11 12.5 0.1 4.3 4 1 1 5 5 5 1 Glyoxalase-like domain CppA_N PF14506.6 KXL48007.1 - 0.00066 19.7 0.1 0.57 10.2 0.1 2.3 2 0 0 2 2 2 2 CppA N-terminal DUF1338 PF07063.13 KXL48007.1 - 0.0025 17.1 0.1 24 4.0 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1338) MoaF PF10703.9 KXL48007.1 - 0.028 14.4 0.0 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 MoaF N-terminal domain CTP_transf_like PF01467.26 KXL48008.1 - 5.7e-22 78.5 0.0 7.7e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like HU-CCDC81_bac_1 PF18174.1 KXL48008.1 - 0.038 13.9 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 1 DUF5131 PF07505.11 KXL48008.1 - 0.14 11.6 0.1 0.47 9.9 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF5131) E1_dh PF00676.20 KXL48009.1 - 4.8e-91 304.8 0.0 6.1e-91 304.5 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KXL48009.1 - 9.7e-05 22.2 0.1 0.00085 19.1 0.1 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 KXL48009.1 - 0.017 14.3 0.0 0.04 13.1 0.0 1.5 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Ferritin PF00210.24 KXL48009.1 - 0.099 12.6 0.4 0.17 11.8 0.4 1.3 1 0 0 1 1 1 0 Ferritin-like domain Med7 PF05983.11 KXL48010.1 - 1.4e-52 178.6 0.9 1.5e-52 178.4 0.9 1.0 1 0 0 1 1 1 1 MED7 protein BLOC1_2 PF10046.9 KXL48010.1 - 0.065 13.5 0.3 0.11 12.8 0.3 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PAP2 PF01569.21 KXL48011.1 - 4.9e-28 97.6 1.4 4.9e-28 97.6 1.4 2.1 2 0 0 2 2 2 1 PAP2 superfamily HisKA_7TM PF16927.5 KXL48011.1 - 0.0092 16.0 5.9 0.022 14.8 0.8 2.2 2 0 0 2 2 2 1 N-terminal 7TM region of histidine kinase YhhN PF07947.14 KXL48011.1 - 0.015 14.9 0.9 0.015 14.9 0.9 2.2 3 0 0 3 3 3 0 YhhN family DUF1772 PF08592.11 KXL48011.1 - 1.5 9.1 5.8 13 6.1 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Cu-oxidase_3 PF07732.15 KXL48012.1 - 1.9e-42 144.0 8.5 8.8e-41 138.7 2.7 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXL48012.1 - 2.3e-39 134.3 6.3 5.7e-32 110.3 0.1 3.7 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 KXL48012.1 - 1.6e-38 132.3 0.4 6.1e-38 130.4 0.1 2.1 2 0 0 2 2 2 1 Multicopper oxidase p450 PF00067.22 KXL48014.1 - 1.6e-74 251.4 0.0 3.3e-74 250.3 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Ubie_methyltran PF01209.18 KXL48015.1 - 4.9e-59 199.5 0.0 2.1e-58 197.4 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KXL48015.1 - 2.3e-16 60.3 0.0 5.5e-16 59.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL48015.1 - 3e-13 50.2 0.0 9.2e-13 48.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL48015.1 - 5.6e-13 49.0 0.0 6.8e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL48015.1 - 5.5e-10 39.9 0.0 1.2e-09 38.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXL48015.1 - 3.7e-07 30.1 0.0 5.6e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KXL48015.1 - 0.14 13.2 0.0 0.36 11.9 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Diphthamide_syn PF01866.17 KXL48017.1 - 3.3e-87 292.7 0.0 5.3e-87 292.1 0.0 1.3 1 1 0 1 1 1 1 Putative diphthamide synthesis protein Keratin_assoc PF09775.9 KXL48018.1 - 0.011 15.4 0.2 0.012 15.3 0.2 1.1 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 Complex1_LYR PF05347.15 KXL48019.1 - 3.7e-07 30.1 2.4 6e-07 29.4 0.2 2.4 2 0 0 2 2 2 1 Complex 1 protein (LYR family) VPS9 PF02204.18 KXL48020.1 - 3.2e-28 98.0 0.0 5.8e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KXL48020.1 - 9.7e-16 57.8 0.3 2.9e-15 56.3 0.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 KXL48020.1 - 1.4e-11 43.8 0.3 1.7e-10 40.4 0.0 2.3 2 0 0 2 2 2 1 CUE domain DCB PF16213.5 KXL48021.1 - 1.4e-42 145.4 2.3 1.4e-42 145.4 2.3 2.9 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 KXL48021.1 - 1.4e-29 103.1 0.0 1.4e-29 103.1 0.0 3.7 5 0 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 KXL48021.1 - 1.2e-12 46.8 0.1 3.4e-11 42.1 0.1 2.6 2 0 0 2 2 2 1 C-terminal region of Mon2 protein DUF1981 PF09324.10 KXL48021.1 - 0.00011 22.0 0.3 0.13 12.1 0.0 4.8 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) RTP1_C1 PF10363.9 KXL48021.1 - 0.13 12.5 3.8 4 7.7 0.0 4.4 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 UME PF08064.13 KXL48021.1 - 0.26 11.2 2.9 3.4 7.6 0.0 4.2 4 1 0 4 4 4 0 UME (NUC010) domain DUF948 PF06103.11 KXL48021.1 - 1.1 9.5 4.7 10 6.5 0.2 3.7 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Ribonuc_P_40 PF08584.11 KXL48022.1 - 3.4e-26 92.2 0.0 4.5e-26 91.8 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit DUF2069 PF09842.9 KXL48022.1 - 0.037 14.2 0.4 0.078 13.2 0.4 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2069) DUF5337 PF17272.2 KXL48024.1 - 0.13 12.2 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5337) LSM PF01423.22 KXL48025.1 - 5.6e-16 58.0 0.5 7.8e-16 57.5 0.2 1.4 2 0 0 2 2 2 1 LSM domain FF PF01846.19 KXL48026.1 - 7.5e-42 141.3 12.5 2.4e-11 43.6 0.0 5.9 5 0 0 5 5 5 5 FF domain WW PF00397.26 KXL48026.1 - 2.7e-18 65.7 8.3 8e-09 35.4 1.3 2.7 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 KXL48026.1 - 1.3e-06 29.0 5.4 0.56 10.9 0.0 5.3 2 1 3 5 5 5 3 p190-A and -B Rho GAPs FF domain EDS1_EP PF18117.1 KXL48026.1 - 0.48 10.9 7.7 1.6 9.2 0.5 3.2 2 1 0 2 2 2 0 Enhanced disease susceptibility 1 protein EP domain SHIRT PF18655.1 KXL48027.1 - 0.044 14.4 0.1 0.056 14.0 0.1 1.2 1 0 0 1 1 1 0 SHIRT domain ABC_tran PF00005.27 KXL48028.1 - 3.9e-37 127.8 0.0 3.8e-17 63.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXL48028.1 - 2.6e-12 46.6 2.0 0.00082 18.9 0.0 4.0 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KXL48028.1 - 3.8e-10 40.1 3.8 0.13 12.0 1.0 4.3 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KXL48028.1 - 1.3e-06 28.7 0.0 0.00068 19.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KXL48028.1 - 2.2e-06 27.7 0.7 0.069 12.8 0.3 3.0 2 1 0 3 3 3 2 AAA ATPase domain AAA PF00004.29 KXL48028.1 - 4.4e-06 27.2 0.1 0.031 14.7 0.1 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KXL48028.1 - 8.7e-06 25.8 0.0 0.031 14.2 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_16 PF13191.6 KXL48028.1 - 2.9e-05 24.5 0.0 0.015 15.7 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_13 PF13166.6 KXL48028.1 - 0.0001 21.1 0.8 0.00014 20.6 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KXL48028.1 - 0.00011 22.0 0.4 0.032 13.9 0.1 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KXL48028.1 - 0.00021 21.2 0.4 0.47 10.3 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 KXL48028.1 - 0.00027 21.5 0.0 0.6 10.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain SRP54 PF00448.22 KXL48028.1 - 0.00037 20.2 2.2 0.073 12.7 0.1 2.3 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 KXL48028.1 - 0.00055 20.3 0.1 0.63 10.5 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 KXL48028.1 - 0.0022 18.1 0.1 5.6 7.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 KXL48028.1 - 0.0023 17.2 0.0 0.47 9.6 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_7 PF12775.7 KXL48028.1 - 0.0029 17.1 1.5 0.031 13.8 0.1 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region NACHT PF05729.12 KXL48028.1 - 0.0034 17.3 2.0 0.53 10.2 0.0 2.4 2 0 0 2 2 2 1 NACHT domain TsaE PF02367.17 KXL48028.1 - 0.0035 17.3 0.2 0.055 13.5 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 KXL48028.1 - 0.0038 16.9 1.4 1.2 8.9 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.6 KXL48028.1 - 0.0042 17.4 0.1 1.7 8.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain DLIC PF05783.11 KXL48028.1 - 0.0043 15.9 0.0 0.0081 15.0 0.0 1.4 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) AAA_30 PF13604.6 KXL48028.1 - 0.01 15.5 0.2 1.7 8.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 KXL48028.1 - 0.018 14.8 0.2 4.8 6.8 0.0 2.8 2 0 0 2 2 2 0 Thymidylate kinase VirE PF05272.11 KXL48028.1 - 0.028 14.1 0.0 9.5 5.9 0.0 2.5 2 0 0 2 2 2 0 Virulence-associated protein E AAA_5 PF07728.14 KXL48028.1 - 0.039 14.0 0.1 3.5 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 KXL48028.1 - 0.041 13.2 0.2 0.093 12.1 0.2 1.5 1 0 0 1 1 1 0 KaiC DnaB_C PF03796.15 KXL48028.1 - 0.045 13.1 0.0 0.23 10.8 0.0 1.9 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_14 PF13173.6 KXL48028.1 - 0.052 13.6 1.8 3.3 7.7 0.1 2.9 2 2 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KXL48028.1 - 0.064 13.4 0.9 8.8 6.4 0.0 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase G-alpha PF00503.20 KXL48028.1 - 0.091 11.9 0.7 3.7 6.6 0.0 2.6 3 0 0 3 3 3 0 G-protein alpha subunit PduV-EutP PF10662.9 KXL48028.1 - 0.096 12.4 0.1 0.096 12.4 0.1 2.5 4 0 0 4 4 3 0 Ethanolamine utilisation - propanediol utilisation dNK PF01712.19 KXL48028.1 - 0.12 12.2 0.3 33 4.3 0.0 3.1 3 0 0 3 3 3 0 Deoxynucleoside kinase AAA_25 PF13481.6 KXL48028.1 - 0.13 11.8 0.4 1.9 8.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Rad51 PF08423.11 KXL48028.1 - 0.22 10.7 0.6 1.4 8.1 0.0 2.3 3 0 0 3 3 3 0 Rad51 NTPase_1 PF03266.15 KXL48028.1 - 0.27 11.1 3.4 9.7 6.1 0.1 3.1 3 0 0 3 3 3 0 NTPase AAA_23 PF13476.6 KXL48028.1 - 0.32 11.5 8.8 0.29 11.6 0.7 2.6 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 KXL48028.1 - 0.95 9.7 3.6 1.5 9.1 0.1 2.7 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase SNF2_N PF00176.23 KXL48029.1 - 1.2e-55 188.6 0.0 2.2e-55 187.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 KXL48029.1 - 2.2e-25 88.3 3.9 1.9e-16 59.7 0.9 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 KXL48029.1 - 2.7e-19 69.6 0.0 6.5e-19 68.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 KXL48029.1 - 4.8e-16 59.0 0.2 1.6e-15 57.3 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) HDA2-3 PF11496.8 KXL48029.1 - 3.7e-08 32.9 0.1 1.5e-07 30.9 0.1 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 KXL48029.1 - 3.2e-06 27.2 0.0 1.7e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SLIDE PF09111.10 KXL48029.1 - 0.0064 16.5 0.0 0.0064 16.5 0.0 3.0 3 0 0 3 3 3 1 SLIDE Cdh1_DBD_1 PF18196.1 KXL48029.1 - 0.008 16.5 2.7 0.008 16.5 2.7 4.7 4 1 1 5 5 4 2 Chromodomain helicase DNA-binding domain 1 CHDCT2 PF08074.11 KXL48029.1 - 0.029 14.5 3.3 0.47 10.6 0.0 3.6 4 0 0 4 4 4 0 CHDCT2 (NUC038) domain Chromo_shadow PF01393.19 KXL48029.1 - 0.06 13.5 0.1 2.1 8.5 0.0 2.7 2 0 0 2 2 2 0 Chromo shadow domain Tudor-knot PF11717.8 KXL48029.1 - 0.11 12.4 0.1 2.5 8.1 0.0 2.7 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain AAA_22 PF13401.6 KXL48029.1 - 0.14 12.5 0.0 0.64 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF3808 PF10300.9 KXL48030.1 - 3.2e-134 448.3 4.0 3.9e-134 448.0 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) Interferon PF00143.19 KXL48030.1 - 0.068 13.4 0.5 0.19 11.9 0.5 1.7 1 0 0 1 1 1 0 Interferon alpha/beta domain PTS_IIA PF02255.16 KXL48030.1 - 1.6 8.8 5.8 12 6.0 0.0 3.8 3 1 1 4 4 4 0 PTS system, Lactose/Cellobiose specific IIA subunit DUF2256 PF10013.9 KXL48031.1 - 0.00026 21.0 2.8 0.00064 19.8 2.8 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) Zn_ribbon_2 PF12674.7 KXL48031.1 - 0.046 14.4 0.1 0.087 13.5 0.1 1.5 1 0 0 1 1 1 0 Putative zinc ribbon domain zf-MYND PF01753.18 KXL48031.1 - 0.22 11.7 2.9 0.53 10.4 2.9 1.6 1 0 0 1 1 1 0 MYND finger Metallophos PF00149.28 KXL48032.1 - 3.2e-09 37.6 0.8 7.9e-09 36.3 0.8 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TDRP PF15683.5 KXL48032.1 - 0.085 12.8 3.9 0.2 11.6 3.9 1.5 1 0 0 1 1 1 0 Testis development-related protein p450 PF00067.22 KXL48033.1 - 1.7e-68 231.5 0.0 2.6e-68 230.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 KXL48033.1 - 4.2e-29 101.7 0.0 8.1e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KXL48033.1 - 2.6e-19 69.8 0.0 5.9e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KXL48033.1 - 3.5e-12 46.9 0.0 9e-12 45.6 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KXL48033.1 - 0.0044 17.2 0.0 0.1 12.7 0.0 2.8 2 1 1 3 3 3 1 Ferric reductase NAD binding domain Flavodoxin_5 PF12724.7 KXL48033.1 - 0.07 13.4 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain MFS_1 PF07690.16 KXL48034.1 - 8.8e-39 133.4 46.4 7.4e-38 130.4 43.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily V_ATPase_I PF01496.19 KXL48034.1 - 0.21 9.5 0.0 0.31 8.9 0.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4746 PF15928.5 KXL48034.1 - 4.8 6.5 10.2 11 5.4 9.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) F-box-like PF12937.7 KXL48035.1 - 7e-05 22.6 0.3 0.0008 19.2 0.3 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXL48035.1 - 0.024 14.5 0.1 0.085 12.8 0.0 2.0 2 0 0 2 2 2 0 F-box domain FAD_binding_4 PF01565.23 KXL48036.1 - 5.5e-18 65.0 0.2 9.2e-18 64.3 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXL48036.1 - 1.2e-08 35.0 0.0 2.3e-07 30.8 0.1 2.3 2 0 0 2 2 2 1 Berberine and berberine like Dioxygenase_C PF00775.21 KXL48036.1 - 0.05 13.0 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 Dioxygenase Secretogranin_V PF05281.11 KXL48036.1 - 0.28 10.8 2.3 0.33 10.6 0.3 1.9 2 0 0 2 2 2 0 Neuroendocrine protein 7B2 precursor (Secretogranin V) MFS_1 PF07690.16 KXL48037.1 - 3.7e-10 39.3 33.3 8.2e-10 38.1 33.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Keratin_assoc PF09775.9 KXL48037.1 - 2.2 8.0 5.4 2.8 7.6 1.6 2.4 2 0 0 2 2 2 0 Keratinocyte-associated protein 2 DUF3096 PF11295.8 KXL48037.1 - 5.7 6.7 6.9 23 4.8 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3096) CPL PF08144.11 KXL48039.1 - 1.2e-28 100.3 0.0 3.1e-27 95.7 0.0 3.1 3 0 0 3 3 3 1 CPL (NUC119) domain DrrA_P4M PF14860.6 KXL48039.1 - 0.023 14.5 2.6 0.11 12.3 2.6 2.2 1 0 0 1 1 1 0 DrrA phosphatidylinositol 4-phosphate binding domain SCHIP-1 PF10148.9 KXL48039.1 - 0.031 13.9 2.4 0.061 12.9 2.4 1.4 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 AA_permease PF00324.21 KXL48040.1 - 9.5e-132 440.0 46.7 1.2e-131 439.7 46.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXL48040.1 - 2.3e-25 89.3 51.6 2.7e-25 89.1 51.6 1.0 1 0 0 1 1 1 1 Amino acid permease HATPase_c PF02518.26 KXL48041.1 - 9.1e-23 80.9 0.1 4.2e-22 78.8 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXL48041.1 - 4.9e-19 68.6 0.4 1.2e-18 67.3 0.4 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KXL48041.1 - 2e-10 40.5 0.1 5.4e-10 39.2 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 KXL48041.1 - 1.2e-06 28.7 0.1 3.1e-06 27.4 0.1 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KXL48041.1 - 0.00066 19.9 0.0 0.0066 16.7 0.0 2.6 3 0 0 3 3 3 1 PAS fold PAS PF00989.25 KXL48041.1 - 0.011 15.7 0.0 0.032 14.2 0.0 1.8 1 0 0 1 1 1 0 PAS fold PAS_8 PF13188.7 KXL48041.1 - 0.04 13.9 0.0 0.23 11.5 0.0 2.2 2 0 0 2 2 2 0 PAS domain PAS_7 PF12860.7 KXL48041.1 - 0.048 13.8 0.0 2.8 8.1 0.0 2.8 2 0 0 2 2 2 0 PAS fold zf-U1 PF06220.12 KXL48042.1 - 1.2e-07 31.3 0.3 2.6e-07 30.3 0.3 1.6 1 0 0 1 1 1 1 U1 zinc finger FA_hydroxylase PF04116.13 KXL48043.1 - 8.1e-13 48.9 4.5 8.1e-13 48.9 4.5 2.5 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily GtrA PF04138.14 KXL48043.1 - 3.4 7.9 7.4 6.6 7.0 0.6 3.0 3 1 0 3 3 3 0 GtrA-like protein Herpes_UL49_5 PF05702.11 KXL48044.1 - 0.65 10.1 3.3 13 6.0 0.1 2.6 2 1 0 2 2 2 0 Herpesvirus UL49.5 envelope/tegument protein DUF3425 PF11905.8 KXL48045.1 - 8e-13 48.4 0.1 2e-12 47.2 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) Macoilin PF09726.9 KXL48045.1 - 0.25 9.9 1.8 0.3 9.6 1.8 1.1 1 0 0 1 1 1 0 Macoilin family FAM70 PF14967.6 KXL48045.1 - 0.26 10.7 3.6 0.35 10.3 3.6 1.1 1 0 0 1 1 1 0 FAM70 protein Lin-8 PF03353.15 KXL48045.1 - 0.28 10.7 2.9 0.38 10.3 2.9 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist bZIP_1 PF00170.21 KXL48045.1 - 1.4 9.1 8.1 0.15 12.2 3.7 1.7 2 0 0 2 2 2 0 bZIP transcription factor NPR3 PF03666.13 KXL48045.1 - 3.9 6.2 7.8 5.1 5.8 7.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Abhydrolase_1 PF00561.20 KXL48046.1 - 1.8e-09 37.7 0.0 8.4e-09 35.4 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXL48046.1 - 1.2e-08 35.8 5.8 2.2e-06 28.4 5.2 3.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Glycophorin_A PF01102.18 KXL48047.1 - 0.012 15.9 0.0 0.032 14.5 0.0 1.7 1 0 0 1 1 1 0 Glycophorin A DUF5305 PF17231.2 KXL48047.1 - 0.049 13.0 0.2 1.3 8.4 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5305) DUF4834 PF16118.5 KXL48047.1 - 0.18 12.8 0.0 14 6.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Adeno_E3_CR2 PF02439.15 KXL48047.1 - 1.3 8.9 4.8 2.9 7.7 4.8 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Fungal_trans_2 PF11951.8 KXL48048.1 - 3.6e-09 35.9 0.2 5.7e-09 35.3 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL48048.1 - 6.2e-08 32.6 6.7 1.3e-07 31.6 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1269 PF06897.12 KXL48049.1 - 0.22 11.8 1.8 2.5 8.4 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) Aa_trans PF01490.18 KXL48051.1 - 3.3e-26 91.9 34.7 4.3e-26 91.6 34.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4231 PF14015.6 KXL48051.1 - 7.4 7.1 14.7 15 6.1 1.1 4.1 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) PEMT PF04191.13 KXL48052.1 - 2.8e-34 117.7 2.5 4.4e-34 117.1 2.5 1.3 1 0 0 1 1 1 1 Phospholipid methyltransferase RUN PF02759.19 KXL48053.1 - 0.14 12.1 0.0 0.16 11.9 0.0 1.3 1 1 0 1 1 1 0 RUN domain Granulin PF00396.18 KXL48054.1 - 1.3 9.4 13.4 3.4 8.1 13.5 1.7 1 1 0 1 1 1 0 Granulin Aldo_ket_red PF00248.21 KXL48055.1 - 1.8e-66 224.3 0.0 2.5e-66 223.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_transf_7C PF02709.14 KXL48055.1 - 0.14 11.8 0.1 0.98 9.1 0.2 2.2 2 0 0 2 2 2 0 N-terminal domain of galactosyltransferase PhyH PF05721.13 KXL48056.1 - 0.0026 18.0 0.0 0.036 14.3 0.0 2.1 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KXL48056.1 - 0.013 14.3 0.0 3.6 6.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1479) AMP-binding PF00501.28 KXL48057.1 - 4.1e-17 61.9 0.0 6e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme NUMOD1 PF07453.13 KXL48058.1 - 0.00038 20.6 0.0 0.0006 20.0 0.0 1.4 1 0 0 1 1 1 1 NUMOD1 domain HTH_psq PF05225.16 KXL48058.1 - 0.0015 18.2 0.2 0.002 17.8 0.2 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.6 KXL48058.1 - 0.006 16.7 0.1 0.0096 16.0 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 KXL48058.1 - 0.02 15.3 0.1 0.026 14.9 0.1 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KXL48058.1 - 0.044 13.2 0.0 0.085 12.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_50 PF18024.1 KXL48058.1 - 0.13 11.9 1.4 0.4 10.3 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_36 PF13730.6 KXL48058.1 - 0.16 11.9 0.0 0.59 10.1 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain zf-C2H2_4 PF13894.6 KXL48059.1 - 1.1e-05 25.8 5.8 0.014 16.2 1.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXL48059.1 - 0.009 16.3 3.2 2.9 8.3 1.1 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KXL48059.1 - 0.022 15.2 7.7 0.45 11.1 2.5 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Kinesin PF00225.23 KXL48061.1 - 9.1e-115 383.1 0.0 1.2e-114 382.7 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXL48061.1 - 2e-27 96.0 0.2 6.7e-27 94.2 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding AAA_33 PF13671.6 KXL48061.1 - 0.035 14.3 0.1 0.19 11.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Bul1_C PF04426.12 KXL48061.1 - 0.075 12.4 1.5 0.18 11.2 1.5 1.6 1 0 0 1 1 1 0 Bul1 C terminus HEPN_Apea PF18739.1 KXL48061.1 - 0.14 12.6 0.4 0.36 11.3 0.4 1.7 1 0 0 1 1 1 0 Apea-like HEPN DUF932 PF06067.11 KXL48061.1 - 0.27 11.0 4.3 0.55 9.9 4.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF932) T3SSipB PF16535.5 KXL48061.1 - 0.31 11.5 6.5 0.61 10.5 0.8 2.4 2 0 0 2 2 2 0 Type III cell invasion protein SipB ADH_zinc_N PF00107.26 KXL48062.1 - 1.2e-05 25.3 0.0 5e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXL48062.1 - 3.4e-05 23.7 0.0 8.8e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF4345 PF14248.6 KXL48063.1 - 0.59 10.0 5.9 4.2 7.3 2.8 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4345) ECH_1 PF00378.20 KXL48064.1 - 2.2e-44 151.7 0.0 3.9e-43 147.6 0.0 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXL48064.1 - 2.7e-24 86.3 0.3 1.7e-22 80.4 0.4 2.5 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KXL48064.1 - 0.0051 16.8 0.1 0.021 14.8 0.0 1.8 1 1 1 2 2 2 1 Peptidase family S49 DNA_ligase_C PF17879.1 KXL48065.1 - 0.15 12.1 0.1 2.2 8.4 0.1 2.0 1 1 1 2 2 2 0 DNA ligase C-terminal domain ILVD_EDD PF00920.21 KXL48066.1 - 6.2e-208 691.6 0.4 7.1e-208 691.4 0.4 1.0 1 0 0 1 1 1 1 Dehydratase family adh_short_C2 PF13561.6 KXL48067.1 - 1.9e-61 207.6 0.2 2.2e-61 207.4 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL48067.1 - 2.1e-41 141.5 0.6 2.7e-41 141.2 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL48067.1 - 1.9e-13 50.7 0.1 2.8e-13 50.2 0.1 1.1 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KXL48067.1 - 0.011 16.0 0.1 0.018 15.3 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KXL48067.1 - 0.019 15.4 0.1 0.039 14.4 0.1 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KXL48067.1 - 0.025 13.9 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 KXL48067.1 - 0.027 13.9 0.2 0.11 12.0 0.2 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_hydro_25 PF01183.20 KXL48068.1 - 1.3e-39 136.2 0.0 1.6e-39 135.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 AAA_18 PF13238.6 KXL48071.1 - 0.00079 20.0 0.0 0.0046 17.5 0.0 2.1 1 1 1 2 2 2 1 AAA domain CPT PF07931.12 KXL48071.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Peptidase_C15 PF01470.17 KXL48072.1 - 0.0099 16.1 0.1 0.015 15.5 0.1 1.2 1 1 0 1 1 1 1 Pyroglutamyl peptidase FtsK_SpoIIIE PF01580.18 KXL48072.1 - 0.012 15.0 0.1 0.022 14.1 0.1 1.4 1 1 0 1 1 1 0 FtsK/SpoIIIE family PknG_TPR PF16918.5 KXL48072.1 - 0.07 11.8 0.0 0.086 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat DXP_reductoisom PF02670.16 KXL48072.1 - 0.17 12.6 0.1 0.25 12.1 0.1 1.3 1 1 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Gpr1_Fun34_YaaH PF01184.19 KXL48074.1 - 8.8e-82 273.7 16.9 1e-81 273.5 16.9 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Clathrin PF00637.20 KXL48075.1 - 0.12 12.2 0.1 0.43 10.4 0.1 1.9 2 0 0 2 2 2 0 Region in Clathrin and VPS DUF1673 PF07895.11 KXL48076.1 - 0.011 15.5 2.6 0.012 15.3 2.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) Plasmodium_Vir PF05795.11 KXL48076.1 - 0.15 11.5 0.4 0.16 11.4 0.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Tetraspanin PF00335.20 KXL48076.1 - 0.2 11.4 5.7 0.19 11.4 5.7 1.1 1 0 0 1 1 1 0 Tetraspanin family Ac81 PF05820.11 KXL48076.1 - 0.92 9.0 9.2 1.3 8.6 9.2 1.4 1 0 0 1 1 1 0 Baculoviridae AC81 ABC2_membrane_3 PF12698.7 KXL48076.1 - 2.5 7.1 19.7 3 6.9 19.7 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein EVC2_like PF12297.8 KXL48076.1 - 3 6.4 4.9 3.3 6.3 4.9 1.0 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein DUF2207 PF09972.9 KXL48076.1 - 7.4 5.2 8.7 8.5 5.0 8.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Fungal_trans PF04082.18 KXL48077.1 - 3.7e-18 65.5 0.0 8.4e-18 64.4 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL48077.1 - 1.8e-09 37.6 9.7 3e-09 36.8 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CASP_C PF08172.12 KXL48077.1 - 0.014 14.8 0.4 0.022 14.1 0.4 1.2 1 0 0 1 1 1 0 CASP C terminal Rox3 PF08633.10 KXL48078.1 - 6.6e-49 167.0 0.4 1.1e-48 166.3 0.4 1.4 1 0 0 1 1 1 1 Rox3 mediator complex subunit Rad10 PF03834.14 KXL48079.1 - 4.6e-48 162.0 0.0 8.2e-48 161.2 0.0 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Lact-deh-memb PF09330.11 KXL48079.1 - 0.0016 17.9 0.0 0.19 11.0 0.0 2.2 2 0 0 2 2 2 2 D-lactate dehydrogenase, membrane binding HHH_5 PF14520.6 KXL48079.1 - 0.061 13.9 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain Zn_clus PF00172.18 KXL48080.1 - 2.2e-07 30.9 7.3 2.2e-07 30.9 7.3 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BOP1NT PF08145.12 KXL48081.1 - 5e-103 344.6 5.6 6.5e-103 344.2 5.6 1.1 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 KXL48081.1 - 8.2e-25 86.6 7.6 4e-11 43.3 0.4 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL48081.1 - 2.8e-09 37.1 0.0 4.4e-05 23.7 0.0 3.8 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nop53 PF07767.11 KXL48081.1 - 0.054 12.9 0.3 0.087 12.2 0.3 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) p450 PF00067.22 KXL48082.1 - 2.3e-75 254.1 0.0 2.7e-75 253.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pro_CA PF00484.19 KXL48083.1 - 1.3e-12 48.3 0.3 1.9e-11 44.5 0.3 2.0 1 1 0 1 1 1 1 Carbonic anhydrase Asn_synthase PF00733.21 KXL48084.1 - 2.7e-15 56.9 0.2 5.3e-06 26.3 0.0 3.1 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 KXL48084.1 - 2.7e-06 27.3 0.0 1e-05 25.4 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KXL48084.1 - 0.0043 17.3 0.0 0.013 15.7 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase domain DSS1_SEM1 PF05160.13 KXL48085.1 - 8.3e-23 80.2 17.3 8.3e-23 80.2 17.3 1.4 1 1 0 1 1 1 1 DSS1/SEM1 family DUF3889 PF13028.6 KXL48085.1 - 0.12 12.3 0.9 0.16 11.9 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3889) PGK PF00162.19 KXL48086.1 - 1.2e-152 508.3 0.9 1.4e-152 508.1 0.9 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 KXL48086.1 - 0.00037 20.5 0.0 0.046 13.7 0.0 3.1 3 1 0 3 3 3 1 PA domain DUF3530 PF12048.8 KXL48086.1 - 0.064 12.7 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Mpv17_PMP22 PF04117.12 KXL48087.1 - 5.2e-20 71.4 0.4 5.2e-20 71.4 0.4 1.9 2 0 0 2 2 2 1 Mpv17 / PMP22 family HisKA_4TM PF16926.5 KXL48087.1 - 0.00048 19.7 0.0 0.00079 19.0 0.0 1.3 1 0 0 1 1 1 1 Archaeal 4TM region of histidine kinase DUF5129 PF17173.4 KXL48087.1 - 0.13 11.3 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5129) CUE PF02845.16 KXL48088.1 - 2.7e-10 39.7 0.0 4.7e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 CUE domain eRF1_2 PF03464.15 KXL48088.1 - 0.14 12.4 0.1 22 5.3 0.0 2.3 2 0 0 2 2 2 0 eRF1 domain 2 HA2 PF04408.23 KXL48089.1 - 9.1e-18 64.5 0.1 2.2e-17 63.3 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KXL48089.1 - 2.3e-14 53.5 0.0 5.4e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KXL48089.1 - 2.9e-10 40.5 0.0 6.1e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXL48089.1 - 0.0087 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase PITH PF06201.13 KXL48090.1 - 1e-43 149.2 0.1 1.2e-43 148.9 0.1 1.1 1 0 0 1 1 1 1 PITH domain Sad1_UNC PF07738.13 KXL48090.1 - 0.024 14.7 0.0 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal MFS_1 PF07690.16 KXL48091.1 - 4.4e-34 117.9 38.5 4.4e-34 117.9 38.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KXL48091.1 - 0.0081 14.5 6.3 0.01 14.2 4.1 2.0 1 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family ESSS PF10183.9 KXL48091.1 - 0.06 13.6 0.1 0.2 11.9 0.1 1.9 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Sugar_tr PF00083.24 KXL48092.1 - 1e-101 341.1 31.0 1.2e-101 340.9 31.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL48092.1 - 4.9e-34 117.8 51.4 2.2e-29 102.5 25.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ost5 PF05251.12 KXL48092.1 - 0.028 14.7 0.4 0.028 14.7 0.4 3.8 4 0 0 4 4 4 0 Oligosaccharyltransferase subunit 5 PEP-utilisers_N PF05524.13 KXL48092.1 - 0.15 12.2 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal MFS_2 PF13347.6 KXL48092.1 - 0.37 9.3 25.9 0.012 14.2 5.4 3.4 1 1 1 3 3 3 0 MFS/sugar transport protein Sortilin_C PF15901.5 KXL48093.1 - 0.035 14.4 0.2 0.057 13.8 0.1 1.4 1 1 0 1 1 1 0 Sortilin, neurotensin receptor 3, C-terminal PI-TkoII_IV PF18714.1 KXL48094.1 - 0.033 13.7 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase II intein Domain IV SUR7 PF06687.12 KXL48095.1 - 3.5e-26 92.2 10.2 4.6e-26 91.8 10.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family SirB PF04247.12 KXL48095.1 - 0.2 11.7 7.7 0.34 11.0 7.7 1.3 1 0 0 1 1 1 0 Invasion gene expression up-regulator, SirB SCIMP PF15050.6 KXL48095.1 - 0.4 11.2 1.5 0.59 10.6 0.0 2.0 2 0 0 2 2 2 0 SCIMP protein DUF2070 PF09843.9 KXL48095.1 - 9.9 4.3 6.5 16 3.6 6.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RTC PF01137.21 KXL48097.1 - 1.6e-59 200.8 0.0 2.3e-59 200.3 0.0 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase TPP_enzyme_C PF02775.21 KXL48100.1 - 0.021 14.6 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Ofd1_CTDD PF10637.9 KXL48101.1 - 1.3e-82 277.0 0.0 1.3e-79 267.2 0.0 2.1 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KXL48101.1 - 5.7e-25 87.8 0.0 1.9e-24 86.1 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KXL48101.1 - 1.4e-13 51.5 0.0 3.6e-13 50.2 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MARVEL PF01284.23 KXL48102.1 - 6.8e-05 22.9 13.8 0.00022 21.3 7.9 2.1 2 0 0 2 2 2 2 Membrane-associating domain DUF1673 PF07895.11 KXL48102.1 - 0.17 11.6 2.3 0.12 12.0 0.6 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1673) MutL_C PF08676.11 KXL48102.1 - 0.21 11.4 0.1 0.32 10.8 0.1 1.2 1 0 0 1 1 1 0 MutL C terminal dimerisation domain DUF4131 PF13567.6 KXL48102.1 - 2.8 7.6 6.2 0.4 10.3 1.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) RabGAP-TBC PF00566.18 KXL48104.1 - 7.9e-47 159.7 0.0 1.1e-46 159.2 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 KXL48104.1 - 8.4e-05 22.2 0.8 0.27 11.3 0.7 3.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KXL48104.1 - 0.00023 21.5 0.1 0.028 14.9 0.3 3.2 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KXL48104.1 - 0.001 18.5 6.0 0.11 12.2 1.0 3.6 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 KXL48104.1 - 0.11 12.0 4.7 0.79 9.3 0.6 3.3 3 0 0 3 3 3 0 EF hand BTB PF00651.31 KXL48105.1 - 7.9e-10 38.9 0.0 1.8e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain MIP PF00230.20 KXL48106.1 - 8.3e-46 156.5 18.6 1e-45 156.2 18.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein Tubulin PF00091.25 KXL48108.1 - 3.1e-68 229.9 0.0 7.7e-68 228.6 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KXL48108.1 - 2.5e-43 147.3 0.0 4e-43 146.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KXL48108.1 - 5.5e-05 23.5 0.0 0.00016 22.0 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KXL48108.1 - 0.0031 16.7 0.0 0.024 13.8 0.0 2.0 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 KXL48108.1 - 0.0036 17.0 0.0 0.0069 16.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain LtrA PF06772.11 KXL48109.1 - 3e-23 82.6 22.3 3e-23 82.6 22.3 2.2 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) DUF2818 PF10993.8 KXL48109.1 - 0.0076 16.8 1.3 0.0076 16.8 1.3 3.2 4 0 0 4 4 4 1 Protein of unknown function (DUF2818) TerC PF03741.16 KXL48109.1 - 0.046 13.4 0.1 0.046 13.4 0.1 2.9 3 1 0 3 3 3 0 Integral membrane protein TerC family DUF3493 PF11998.8 KXL48109.1 - 0.5 10.6 4.6 2.1 8.6 0.3 3.0 1 1 1 2 2 2 0 Low psii accumulation1 / Rep27 DUF2613 PF11021.8 KXL48109.1 - 1.9 8.7 4.6 0.84 9.8 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) Snf7 PF03357.21 KXL48112.1 - 7.8e-38 129.8 9.9 9.3e-38 129.5 9.9 1.1 1 0 0 1 1 1 1 Snf7 Seryl_tRNA_N PF02403.22 KXL48112.1 - 0.014 15.6 0.3 0.014 15.6 0.3 2.7 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain AAA PF00004.29 KXL48113.1 - 3.3e-89 296.1 0.0 2.2e-43 147.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXL48113.1 - 2.6e-18 65.6 0.1 5e-08 32.6 0.0 2.9 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KXL48113.1 - 6.8e-11 42.8 1.7 0.00022 21.7 0.0 4.2 3 2 0 3 3 2 2 AAA ATPase domain AAA_5 PF07728.14 KXL48113.1 - 8e-11 42.1 0.2 7.2e-05 22.8 0.0 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KXL48113.1 - 4.4e-10 39.5 0.0 0.0012 18.7 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KXL48113.1 - 5.7e-09 36.3 0.0 0.001 19.2 0.0 3.1 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KXL48113.1 - 1.5e-08 34.9 0.0 0.0014 18.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KXL48113.1 - 3.4e-08 33.8 0.6 0.088 13.1 0.1 4.4 3 2 1 4 4 3 2 AAA domain Mg_chelatase PF01078.21 KXL48113.1 - 9.4e-07 28.4 0.4 0.035 13.5 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KXL48113.1 - 3e-06 27.6 0.0 0.076 13.4 0.0 2.9 2 1 0 2 2 2 2 RNA helicase AAA_25 PF13481.6 KXL48113.1 - 4e-06 26.5 0.4 0.24 11.0 0.0 3.7 3 1 0 3 3 3 2 AAA domain TIP49 PF06068.13 KXL48113.1 - 6.8e-06 25.5 0.3 0.035 13.3 0.1 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_3 PF07726.11 KXL48113.1 - 6.8e-06 26.0 0.0 0.0049 16.7 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KXL48113.1 - 1.7e-05 24.8 0.0 0.044 13.8 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 KXL48113.1 - 2.1e-05 23.9 0.2 0.068 12.4 0.0 2.9 3 0 0 3 3 3 2 Zeta toxin AAA_14 PF13173.6 KXL48113.1 - 2.3e-05 24.5 0.0 0.22 11.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KXL48113.1 - 2.5e-05 24.8 0.0 0.28 11.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KXL48113.1 - 2.7e-05 24.0 0.2 0.19 11.5 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 KXL48113.1 - 6.6e-05 23.2 0.0 0.081 13.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KXL48113.1 - 9.7e-05 21.9 0.0 0.22 11.0 0.0 2.9 3 0 0 3 3 3 2 P-loop containing dynein motor region Rad17 PF03215.15 KXL48113.1 - 0.00012 22.0 0.0 0.23 11.3 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain PhoH PF02562.16 KXL48113.1 - 0.00017 21.1 0.0 0.34 10.3 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein Sigma54_activat PF00158.26 KXL48113.1 - 0.00026 20.7 0.0 0.76 9.5 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain ABC_tran PF00005.27 KXL48113.1 - 0.00034 21.1 0.0 1 9.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_17 PF13207.6 KXL48113.1 - 0.0004 20.8 0.3 0.95 9.9 0.1 3.2 2 1 0 2 2 2 1 AAA domain ATPase PF06745.13 KXL48113.1 - 0.00042 19.7 0.1 0.72 9.2 0.0 2.7 3 0 0 3 3 3 2 KaiC AAA_11 PF13086.6 KXL48113.1 - 0.00059 19.7 0.0 0.55 10.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 KXL48113.1 - 0.0006 19.1 0.0 0.27 10.4 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Viral_helicase1 PF01443.18 KXL48113.1 - 0.00061 19.6 0.0 0.72 9.6 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 KXL48113.1 - 0.00074 19.5 1.4 1.3 8.9 0.0 3.5 3 1 1 4 4 3 1 NACHT domain TniB PF05621.11 KXL48113.1 - 0.0011 18.4 0.0 0.16 11.3 0.0 2.8 2 0 0 2 2 2 1 Bacterial TniB protein AAA_24 PF13479.6 KXL48113.1 - 0.0017 18.1 0.1 0.56 9.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KXL48113.1 - 0.0035 17.7 0.3 2.2 8.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 KXL48113.1 - 0.0041 17.2 0.0 3.1 7.9 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain ResIII PF04851.15 KXL48113.1 - 0.0069 16.4 0.0 6.7 6.7 0.0 2.7 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 KXL48113.1 - 0.0086 16.0 0.0 6.6 6.6 0.0 3.0 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea SKI PF01202.22 KXL48113.1 - 0.012 15.8 0.1 1.3 9.2 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase NB-ARC PF00931.22 KXL48113.1 - 0.013 14.7 0.1 4.3 6.4 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.6 KXL48113.1 - 0.042 13.6 0.1 10 5.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain CPT PF07931.12 KXL48113.1 - 0.045 13.6 0.0 0.61 9.9 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AFG1_ATPase PF03969.16 KXL48113.1 - 0.078 11.9 0.2 11 4.8 0.0 2.7 3 0 0 3 3 3 0 AFG1-like ATPase Parvo_NS1 PF01057.17 KXL48113.1 - 0.1 11.7 0.2 11 5.1 0.1 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Spindle_Spc25 PF08234.12 KXL48114.1 - 1.1e-22 80.0 0.3 2.3e-22 79.0 0.3 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 CSRNP_N PF16019.5 KXL48114.1 - 0.081 12.8 3.5 0.14 12.0 3.5 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus APG6_N PF17675.1 KXL48114.1 - 1.1 9.8 13.4 0.34 11.4 10.1 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region SIMPL PF04402.14 KXL48114.1 - 1.4 9.3 7.0 5.7 7.3 7.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF541) FapA PF03961.13 KXL48114.1 - 6.8 5.2 5.9 11 4.5 5.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Rrn6 PF10214.9 KXL48115.1 - 1.6e-143 480.2 10.2 2e-143 479.9 10.2 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor DUF2992 PF11208.8 KXL48115.1 - 0.018 15.3 0.2 0.037 14.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Phage_min_cap2 PF06152.11 KXL48115.1 - 0.058 12.3 4.1 0.12 11.3 4.1 1.4 1 0 0 1 1 1 0 Phage minor capsid protein 2 PhoD PF09423.10 KXL48116.1 - 9.2e-07 28.2 0.4 0.00028 20.0 0.1 2.5 2 1 0 2 2 2 2 PhoD-like phosphatase COesterase PF00135.28 KXL48117.1 - 9.4e-91 305.2 0.0 1.4e-90 304.6 0.0 1.2 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXL48117.1 - 0.00055 19.9 0.8 0.0055 16.6 0.8 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXL48117.1 - 0.00079 19.0 0.1 0.0016 18.0 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF3440 PF11922.8 KXL48117.1 - 0.21 11.3 0.0 0.39 10.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) MFS_1 PF07690.16 KXL48118.1 - 6.1e-07 28.7 23.5 0.0023 16.9 13.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Amino_oxidase PF01593.24 KXL48119.1 - 6.2e-15 55.4 0.0 6.6e-15 55.3 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXL48119.1 - 2.7e-11 43.5 0.1 4.5e-11 42.8 0.1 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXL48119.1 - 0.0058 17.2 0.5 0.018 15.6 0.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXL48119.1 - 0.011 15.0 0.1 0.011 15.0 0.1 1.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXL48119.1 - 0.012 14.4 0.2 0.036 12.8 0.1 1.6 1 1 1 2 2 2 0 HI0933-like protein Thi4 PF01946.17 KXL48119.1 - 0.02 14.1 0.1 0.026 13.8 0.1 1.2 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 KXL48119.1 - 0.039 13.0 0.3 0.34 9.9 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain DUF5608 PF18356.1 KXL48119.1 - 0.056 13.4 0.0 0.089 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5608) RXT2_N PF08595.11 KXL48120.1 - 1.6e-38 132.1 0.5 6.6e-38 130.2 0.0 2.1 2 0 0 2 2 2 1 RXT2-like, N-terminal DUF1818 PF08848.11 KXL48120.1 - 0.019 15.0 0.1 0.037 14.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1818) FAD_binding_4 PF01565.23 KXL48121.1 - 1e-15 57.7 0.0 1.6e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Myb_DNA-bind_6 PF13921.6 KXL48122.1 - 4.6e-07 30.0 0.3 3.2e-05 24.1 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KXL48122.1 - 1.8e-05 24.8 1.2 5e-05 23.4 1.2 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain P16-Arc PF04699.14 KXL48124.1 - 9.8e-49 165.6 0.0 1.1e-48 165.4 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Ras PF00071.22 KXL48125.1 - 6.8e-40 136.3 0.0 6.3e-37 126.7 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KXL48125.1 - 1.5e-30 105.9 0.0 2.1e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXL48125.1 - 5.4e-12 45.5 0.0 9.6e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXL48125.1 - 0.0013 18.8 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KXL48125.1 - 0.0072 16.7 0.0 0.016 15.6 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXL48125.1 - 0.04 14.2 0.0 0.13 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KXL48125.1 - 0.073 12.8 0.0 0.11 12.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 KXL48125.1 - 0.088 12.1 0.0 0.46 9.7 0.0 1.9 2 0 0 2 2 2 0 Septin Gtr1_RagA PF04670.12 KXL48125.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KXL48125.1 - 0.22 11.4 0.1 0.56 10.1 0.1 1.7 1 1 0 1 1 1 0 RsgA GTPase MFS_1 PF07690.16 KXL48127.1 - 3.5e-26 92.0 29.7 5.7e-25 88.0 26.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL48127.1 - 8.4e-08 31.5 7.4 8.4e-08 31.5 7.4 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter Methyltransf_25 PF13649.6 KXL48128.1 - 3e-10 40.7 0.0 7.2e-10 39.5 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.13 KXL48128.1 - 4e-10 39.6 0.0 6.3e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KXL48128.1 - 4.1e-09 36.4 0.0 7.9e-09 35.5 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL48128.1 - 2.8e-07 31.1 0.0 8.2e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 KXL48128.1 - 1.8e-06 27.1 0.1 2.7e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 KXL48128.1 - 0.00019 21.4 0.0 0.00033 20.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL48128.1 - 0.00048 20.8 0.0 0.00094 19.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXL48128.1 - 0.00061 19.7 0.0 0.0008 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXL48128.1 - 0.0012 18.2 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KXL48128.1 - 0.0096 15.5 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KXL48128.1 - 0.028 14.4 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.16 KXL48128.1 - 0.092 12.6 0.1 0.21 11.4 0.1 1.6 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Actin PF00022.19 KXL48129.1 - 7.2e-50 169.8 0.0 7.1e-26 90.8 0.0 2.4 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.13 KXL48129.1 - 0.16 10.8 0.0 0.3 9.9 0.0 1.4 1 0 0 1 1 1 0 MreB/Mbl protein Pkinase PF00069.25 KXL48131.1 - 3.9e-48 164.1 0.0 8.5e-48 163.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL48131.1 - 3e-27 95.6 0.0 1.2e-26 93.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXL48131.1 - 0.00063 19.2 0.1 0.00097 18.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXL48131.1 - 0.0036 17.3 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXL48131.1 - 0.0091 15.3 0.0 0.039 13.3 0.0 2.0 2 1 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KXL48131.1 - 0.013 15.1 0.0 0.092 12.4 0.0 2.0 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KXL48131.1 - 0.037 13.6 0.0 0.076 12.6 0.0 1.5 1 1 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.11 KXL48131.1 - 0.18 10.7 0.0 0.31 10.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Sugar_tr PF00083.24 KXL48133.1 - 2.9e-88 296.7 13.9 5.2e-88 295.9 13.9 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL48133.1 - 1.5e-22 80.0 20.7 2.8e-22 79.1 13.6 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXL48133.1 - 0.00071 18.5 6.9 0.14 11.0 0.0 2.5 1 1 0 2 2 2 2 MFS_1 like family Glyco_hydro_16 PF00722.21 KXL48134.1 - 8e-08 32.0 0.0 4.5e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Aminotran_1_2 PF00155.21 KXL48135.1 - 3.2e-37 128.6 0.0 4e-37 128.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KXL48135.1 - 0.049 12.1 0.0 0.076 11.5 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Rad4 PF03835.15 KXL48136.1 - 4.3e-30 104.3 1.5 5.3e-30 104.0 0.0 1.9 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KXL48136.1 - 1.1e-25 89.9 0.4 1.8e-25 89.1 0.4 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KXL48136.1 - 3.4e-21 74.8 1.4 5.3e-21 74.2 0.3 1.9 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KXL48136.1 - 5.5e-16 59.3 3.9 1.1e-15 58.4 0.2 3.3 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KXL48136.1 - 0.00078 19.9 0.0 0.0028 18.1 0.0 2.0 1 1 0 1 1 1 1 Transglutaminase-like superfamily Pkinase PF00069.25 KXL48137.1 - 2.1e-71 240.4 0.0 2.9e-71 239.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL48137.1 - 8.5e-31 107.2 0.0 1.1e-30 106.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXL48137.1 - 0.00032 19.8 0.3 0.0084 15.1 0.0 2.3 3 0 0 3 3 3 1 Haspin like kinase domain APH PF01636.23 KXL48137.1 - 0.0017 18.3 0.0 0.0057 16.6 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXL48137.1 - 0.0033 16.8 0.0 0.0094 15.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 KXL48137.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 KH_1 PF00013.29 KXL48140.1 - 9.3e-89 291.3 30.0 5.4e-12 45.4 0.3 14.2 15 1 0 15 15 15 10 KH domain SLS PF14611.6 KXL48140.1 - 1.4e-11 44.6 2.4 0.0001 22.2 0.1 6.1 4 2 2 6 6 6 2 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 KXL48140.1 - 1e-10 41.3 16.7 0.48 10.3 0.4 7.5 7 0 0 7 7 7 5 KH domain KH_4 PF13083.6 KXL48140.1 - 2.1e-07 30.7 0.9 1.4 8.9 0.1 5.8 5 0 0 5 5 5 1 KH domain BMC PF00936.19 KXL48140.1 - 0.00027 20.9 0.7 52 3.9 0.0 5.0 5 0 0 5 5 5 0 BMC domain DUF3825 PF12873.7 KXL48140.1 - 0.011 15.3 0.2 0.042 13.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3825) DUF2120 PF09893.9 KXL48140.1 - 0.077 13.1 1.9 7.2 6.7 0.2 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) KH_5 PF13184.6 KXL48140.1 - 0.29 11.3 9.8 2.8 8.1 0.1 5.1 6 0 0 6 6 6 0 NusA-like KH domain Phage_holin_3_6 PF07332.11 KXL48141.1 - 5.2 7.1 5.5 4.5 7.3 0.4 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III adh_short PF00106.25 KXL48142.1 - 6e-39 133.5 0.1 8.3e-39 133.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL48142.1 - 1.6e-26 93.3 0.5 2.1e-26 92.9 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL48142.1 - 0.0012 18.8 0.1 0.0059 16.5 0.1 1.8 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 KXL48142.1 - 0.0046 16.1 0.2 0.036 13.2 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KXL48143.1 - 4.4e-35 120.9 0.1 1.5e-34 119.1 0.1 1.9 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL48143.1 - 7.4e-32 110.8 0.6 2.6e-30 105.7 0.6 2.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL48143.1 - 2e-09 37.7 0.1 2e-09 37.7 0.1 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXL48143.1 - 0.0007 19.1 0.2 0.0058 16.1 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 KXL48143.1 - 0.042 13.8 0.1 0.085 12.8 0.1 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Polysacc_synt_2 PF02719.15 KXL48143.1 - 0.043 13.0 0.0 0.069 12.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KXL48143.1 - 0.08 12.3 0.2 0.31 10.4 0.0 1.9 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase LUC7 PF03194.15 KXL48144.1 - 2.6e-74 250.1 3.3 2.6e-74 250.1 3.3 1.3 1 1 0 1 1 1 1 LUC7 N_terminus Occludin_ELL PF07303.13 KXL48144.1 - 0.69 10.7 4.5 4.7 8.0 0.2 3.0 3 0 0 3 3 3 0 Occludin homology domain Laminin_II PF06009.12 KXL48144.1 - 0.82 9.7 6.1 3.2 7.7 0.2 2.5 2 1 0 2 2 2 0 Laminin Domain II DUF4600 PF15372.6 KXL48144.1 - 2.7 8.4 10.6 2.6 8.5 0.5 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4600) Gpi16 PF04113.14 KXL48145.1 - 3.1e-210 699.4 0.0 3.8e-210 699.1 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Ribosomal_L27A PF00828.19 KXL48145.1 - 0.045 14.4 0.0 0.082 13.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A zf-TFIIB PF13453.6 KXL48146.1 - 0.13 11.7 0.1 0.27 10.6 0.1 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger SIR2 PF02146.17 KXL48147.1 - 1.3e-37 129.4 0.0 6.1e-37 127.2 0.0 1.8 1 1 0 1 1 1 1 Sir2 family zf-RING_7 PF02591.15 KXL48147.1 - 0.01 16.0 0.1 0.026 14.7 0.1 1.7 1 0 0 1 1 1 0 C4-type zinc ribbon domain Peptidase_M24 PF00557.24 KXL48148.1 - 3.8e-52 177.0 0.0 6.5e-52 176.3 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KXL48148.1 - 4.2e-39 133.1 0.0 7e-39 132.4 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DIOX_N PF14226.6 KXL48149.1 - 2.5e-12 47.6 0.2 5.8e-12 46.4 0.1 1.5 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXL48149.1 - 1.4e-09 38.3 0.0 7.4e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily AEP1 PF17049.5 KXL48150.1 - 0.034 13.2 0.3 0.044 12.9 0.3 1.1 1 0 0 1 1 1 0 ATPase expression protein 1 zf-Di19 PF05605.12 KXL48151.1 - 0.02 15.2 0.0 0.038 14.3 0.0 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KXL48151.1 - 0.032 15.1 0.1 0.096 13.6 0.1 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KXL48151.1 - 0.045 13.6 0.1 0.077 12.9 0.1 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 KXL48151.1 - 0.071 13.6 0.1 0.2 12.2 0.1 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type Cas_Cas02710 PF09670.10 KXL48151.1 - 0.13 11.0 0.6 0.21 10.4 0.6 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) zf-ribbon_3 PF13248.6 KXL48151.1 - 0.19 11.2 0.2 0.53 9.8 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain SH3BP5 PF05276.14 KXL48151.1 - 0.88 9.3 6.6 0.15 11.9 1.8 1.9 2 0 0 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) SNF2_N PF00176.23 KXL48152.1 - 1.7e-70 237.5 0.0 2.3e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KXL48152.1 - 2.2e-16 59.6 0.0 5.1e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 KXL48152.1 - 1.4e-14 54.3 0.0 8.9e-14 51.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 KXL48152.1 - 1.9e-10 40.4 6.9 4.3e-10 39.3 6.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXL48152.1 - 1.5e-08 34.9 7.0 1.5e-08 34.9 7.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KXL48152.1 - 2.4e-08 33.9 5.7 5.4e-08 32.7 5.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KXL48152.1 - 6.1e-08 32.7 5.5 1.2e-07 31.7 5.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KXL48152.1 - 6.2e-08 32.4 4.3 6.2e-08 32.4 4.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXL48152.1 - 1.4e-06 28.1 6.0 1.4e-06 28.1 6.0 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KXL48152.1 - 2e-06 27.5 6.4 2e-06 27.5 6.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KXL48152.1 - 8.4e-06 25.9 0.0 2.3e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-Nse PF11789.8 KXL48152.1 - 1.4e-05 24.8 3.4 3.3e-05 23.6 3.4 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 KXL48152.1 - 2.3e-05 24.1 4.6 5.9e-05 22.8 4.6 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KXL48152.1 - 3.4e-05 24.0 6.2 0.00014 22.1 6.2 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain U-box PF04564.15 KXL48152.1 - 0.0019 18.3 0.0 0.0062 16.7 0.0 1.9 2 0 0 2 2 2 1 U-box domain zf-ANAPC11 PF12861.7 KXL48152.1 - 0.019 15.0 3.1 0.08 13.0 3.1 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.14 KXL48152.1 - 0.071 13.0 0.5 2.4 8.1 0.0 2.8 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_10 PF16685.5 KXL48152.1 - 0.099 12.8 2.1 0.27 11.4 2.1 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KXL48152.1 - 0.17 11.7 4.3 0.52 10.2 4.3 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 KXL48152.1 - 0.35 10.7 3.3 1 9.1 3.3 1.9 1 0 0 1 1 1 0 RING-like zinc finger DUF1644 PF07800.12 KXL48152.1 - 0.39 10.8 3.8 1.3 9.0 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) DUF4449 PF14613.6 KXL48153.1 - 9.1e-69 230.7 6.5 9.1e-69 230.7 6.5 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Endotoxin_N PF03945.14 KXL48153.1 - 0.012 15.3 2.8 0.028 14.1 1.6 2.2 2 0 0 2 2 2 0 delta endotoxin, N-terminal domain Prp18 PF02840.15 KXL48153.1 - 8.1 6.5 10.3 2.2 8.3 0.0 3.7 2 2 1 4 4 4 0 Prp18 domain Utp8 PF10395.9 KXL48156.1 - 9e-09 34.4 0.0 7.6e-06 24.7 0.0 2.8 3 0 0 3 3 3 2 Utp8 family SIN1_PH PF16979.5 KXL48156.1 - 0.15 12.3 0.0 1.9 8.8 0.0 2.3 2 0 0 2 2 2 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TRAM_LAG1_CLN8 PF03798.16 KXL48158.1 - 2.5e-34 118.8 25.7 3.5e-34 118.3 22.7 2.1 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KXL48158.1 - 2.1e-23 81.7 1.9 1.3e-22 79.2 0.0 2.5 2 0 0 2 2 2 1 TRAM1-like protein TFIIE-A_C PF11521.8 KXL48158.1 - 0.13 12.6 0.6 0.29 11.4 0.6 1.5 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha Med3 PF11593.8 KXL48158.1 - 4.5 6.4 7.6 6.7 5.8 7.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DSPc PF00782.20 KXL48159.1 - 1.3e-28 99.5 0.0 1.5e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KXL48159.1 - 0.088 13.1 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Rit1 DUSP-like domain WD40 PF00400.32 KXL48160.1 - 2.2e-24 85.3 7.7 3.6e-06 27.6 0.0 7.4 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL48160.1 - 2e-06 28.0 0.0 1.8 8.9 0.0 4.1 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXL48160.1 - 0.006 15.3 0.6 1.8 7.1 0.2 3.1 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KXL48160.1 - 0.013 14.5 0.1 0.66 8.9 0.0 3.0 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Snf7 PF03357.21 KXL48161.1 - 5.9e-36 123.7 21.9 8.3e-36 123.2 21.5 1.4 2 0 0 2 2 2 1 Snf7 YlqD PF11068.8 KXL48161.1 - 0.051 14.0 23.1 1.9 8.9 9.4 2.2 1 1 1 2 2 2 0 YlqD protein Exonuc_VII_L PF02601.15 KXL48161.1 - 0.19 11.2 8.1 0.27 10.8 8.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 KXL48161.1 - 1.2 8.4 8.5 1.7 7.9 8.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LMBR1 PF04791.16 KXL48161.1 - 2.3 7.0 3.7 3 6.6 3.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Remorin_C PF03763.13 KXL48161.1 - 3.2 7.7 11.9 0.92 9.4 8.4 1.9 1 1 1 2 2 2 0 Remorin, C-terminal region O-antigen_lig PF13425.6 KXL48161.1 - 6.8 5.4 5.0 8.4 5.1 5.0 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Dynamin_N PF00350.23 KXL48162.1 - 4.2e-16 59.5 0.1 1.4e-15 57.8 0.0 2.0 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KXL48162.1 - 2e-09 37.6 0.0 2e-08 34.3 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXL48162.1 - 4.4e-06 26.4 0.0 0.0028 17.2 0.0 2.8 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain DUF2205 PF10224.9 KXL48162.1 - 0.00017 21.5 0.5 0.00069 19.6 0.5 2.0 1 0 0 1 1 1 1 Short coiled-coil protein IIGP PF05049.13 KXL48162.1 - 0.07 12.2 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_18 PF13238.6 KXL48162.1 - 0.12 12.9 0.0 0.84 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KXL48162.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE USP8_dimer PF08969.11 KXL48162.1 - 0.65 10.2 6.1 3.7 7.7 0.4 3.9 4 0 0 4 4 4 0 USP8 dimerisation domain Abhydrolase_6 PF12697.7 KXL48163.1 - 0.00011 22.9 0.3 0.00017 22.2 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KXL48163.1 - 0.00053 19.8 0.3 0.0012 18.6 0.3 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 KXL48163.1 - 0.0022 17.5 0.0 0.0054 16.3 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KXL48163.1 - 0.0032 16.8 0.1 0.031 13.6 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KXL48163.1 - 0.0043 16.9 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) DUF915 PF06028.11 KXL48163.1 - 0.0051 16.2 0.0 1.7 7.9 0.0 2.8 3 0 0 3 3 3 2 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.20 KXL48163.1 - 0.0092 16.1 0.0 0.037 14.1 0.0 2.1 3 0 0 3 3 3 1 Thioesterase domain DUF3145 PF11343.8 KXL48163.1 - 0.047 13.2 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3145) DUF3237 PF11578.8 KXL48164.1 - 3.3e-23 82.2 0.2 4.1e-18 65.7 0.1 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3237) Vps16_N PF04841.13 KXL48165.1 - 2.7e-95 319.6 0.0 3.7e-95 319.1 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 KXL48165.1 - 4.2e-91 305.3 1.2 6.1e-91 304.8 1.2 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 KXL48165.1 - 7.8e-05 22.9 0.0 0.12 12.7 0.0 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain FATC PF02260.20 KXL48165.1 - 0.087 12.7 0.3 4.1 7.3 0.0 2.6 2 0 0 2 2 2 0 FATC domain Coatomer_WDAD PF04053.14 KXL48165.1 - 0.23 10.5 1.9 1.3 8.0 0.0 2.9 4 0 0 4 4 4 0 Coatomer WD associated region AAA_lid_2 PF17863.1 KXL48166.1 - 0.023 14.5 0.4 0.051 13.4 0.4 1.5 1 0 0 1 1 1 0 AAA lid domain Bestrophin PF01062.21 KXL48167.1 - 1.7e-44 152.4 0.0 2.1e-44 152.1 0.0 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel HA2 PF04408.23 KXL48168.1 - 1e-18 67.6 0.1 7.1e-18 64.9 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KXL48168.1 - 1.4e-13 51.1 0.0 3.3e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KXL48168.1 - 4.2e-12 46.3 0.0 9.5e-12 45.1 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KXL48168.1 - 4.1e-10 39.7 0.3 1.1e-09 38.3 0.3 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase RWD PF05773.22 KXL48168.1 - 6.9e-10 39.2 1.6 1.3e-09 38.3 1.6 1.5 1 0 0 1 1 1 1 RWD domain UBA PF00627.31 KXL48168.1 - 8.1e-06 25.6 0.0 0.053 13.4 0.0 3.2 2 0 0 2 2 2 2 UBA/TS-N domain AAA_29 PF13555.6 KXL48168.1 - 0.0062 16.3 0.1 0.036 13.8 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SSE PF00437.20 KXL48168.1 - 0.0082 15.2 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 KXL48168.1 - 0.036 14.3 2.4 0.25 11.6 2.4 2.2 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KXL48168.1 - 0.052 13.9 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KXL48168.1 - 0.067 12.5 0.1 0.15 11.4 0.1 1.5 1 0 0 1 1 1 0 KaiC HOIP-UBA PF16678.5 KXL48168.1 - 0.07 13.1 0.4 25 4.8 0.0 3.2 3 0 0 3 3 3 0 HOIP UBA domain pair PhoH PF02562.16 KXL48168.1 - 0.11 12.0 0.0 0.26 10.7 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 KXL48168.1 - 0.13 11.8 0.4 0.36 10.4 0.1 1.9 2 1 0 2 2 2 0 AAA domain Invasin_D3 PF09134.10 KXL48168.1 - 2.4 8.5 4.8 1.4 9.3 1.6 2.1 2 0 0 2 2 2 0 Invasin, domain 3 EHN PF06441.12 KXL48169.1 - 1.3e-31 109.1 0.0 2.3e-31 108.3 0.0 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KXL48169.1 - 8.6e-10 38.7 0.0 1.4e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXL48169.1 - 0.032 14.8 0.8 0.11 13.1 0.8 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family AAA PF00004.29 KXL48171.1 - 1.6e-97 323.0 0.0 1.3e-47 161.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXL48171.1 - 6.7e-25 86.6 3.3 6.6e-13 48.2 0.4 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 KXL48171.1 - 6.4e-21 74.3 0.5 1.7e-20 73.0 0.5 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 KXL48171.1 - 4.1e-14 52.6 0.0 4.5e-06 26.5 0.0 3.1 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KXL48171.1 - 8.1e-14 52.1 0.0 1.1e-07 32.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KXL48171.1 - 1.8e-13 51.2 0.0 0.00014 22.3 0.0 4.6 3 2 1 4 4 3 2 AAA ATPase domain AAA_33 PF13671.6 KXL48171.1 - 1.3e-11 44.8 0.0 6e-05 23.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KXL48171.1 - 3.3e-11 43.3 0.5 7.3e-06 26.0 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXL48171.1 - 1.4e-09 38.3 0.4 0.014 15.7 0.1 4.2 2 2 1 3 3 3 2 AAA domain TIP49 PF06068.13 KXL48171.1 - 6.1e-09 35.5 1.3 0.0012 18.1 0.0 3.0 3 1 0 3 3 3 2 TIP49 P-loop domain AAA_18 PF13238.6 KXL48171.1 - 2.2e-07 31.5 0.0 0.031 14.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KXL48171.1 - 3.1e-07 30.2 4.1 0.65 9.5 0.1 4.8 3 2 1 5 5 5 3 AAA domain IstB_IS21 PF01695.17 KXL48171.1 - 3.4e-07 30.2 0.1 0.027 14.2 0.0 2.9 3 0 0 3 3 2 2 IstB-like ATP binding protein CDC48_2 PF02933.17 KXL48171.1 - 4.1e-07 29.7 0.0 1.1e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 RNA_helicase PF00910.22 KXL48171.1 - 5.2e-07 30.0 0.0 0.032 14.6 0.0 2.8 2 0 0 2 2 2 2 RNA helicase ATPase PF06745.13 KXL48171.1 - 5.6e-07 29.1 0.4 0.26 10.6 0.0 3.5 3 0 0 3 3 3 2 KaiC Mg_chelatase PF01078.21 KXL48171.1 - 7.1e-07 28.8 0.7 0.033 13.6 0.0 2.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KXL48171.1 - 1.2e-06 28.6 0.0 0.0088 16.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KXL48171.1 - 4.1e-06 26.4 0.0 0.042 13.4 0.0 3.1 2 2 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 KXL48171.1 - 7.6e-06 25.8 0.0 0.055 13.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 KXL48171.1 - 9.8e-06 25.5 0.2 3.7e-05 23.6 0.1 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain DUF815 PF05673.13 KXL48171.1 - 1.1e-05 24.7 0.0 0.017 14.3 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 KXL48171.1 - 1.8e-05 24.0 0.1 0.098 11.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 KXL48171.1 - 1.8e-05 25.0 0.0 0.31 11.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 KXL48171.1 - 3.7e-05 23.5 0.0 0.42 10.3 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain Bac_DnaA PF00308.18 KXL48171.1 - 4.7e-05 23.3 0.0 0.13 12.1 0.0 2.9 3 0 0 3 3 2 2 Bacterial dnaA protein ABC_tran PF00005.27 KXL48171.1 - 7.3e-05 23.3 0.0 0.65 10.5 0.0 3.5 2 1 0 2 2 2 1 ABC transporter AAA_17 PF13207.6 KXL48171.1 - 8.5e-05 23.0 0.1 0.6 10.5 0.0 3.7 3 0 0 3 3 3 1 AAA domain TsaE PF02367.17 KXL48171.1 - 0.00012 22.0 0.0 0.7 9.9 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 KXL48171.1 - 0.00018 21.5 0.0 0.043 13.8 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KXL48171.1 - 0.00027 20.5 0.4 0.45 9.9 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.11 KXL48171.1 - 0.00042 20.2 0.0 0.83 9.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KXL48171.1 - 0.00054 19.8 1.2 1.5 8.5 0.7 3.0 2 1 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 KXL48171.1 - 0.00068 19.6 0.0 1.5 8.7 0.0 3.6 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea DUF2075 PF09848.9 KXL48171.1 - 0.00075 18.8 0.0 0.91 8.7 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KXL48171.1 - 0.00094 18.9 0.2 1.6 8.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KXL48171.1 - 0.0012 18.8 0.1 1.3 8.9 0.0 3.0 3 0 0 3 3 3 1 NACHT domain AAA_19 PF13245.6 KXL48171.1 - 0.0037 17.6 1.1 7.3 6.9 0.1 3.5 3 1 1 4 4 3 0 AAA domain UFD1 PF03152.14 KXL48171.1 - 0.004 16.6 0.0 0.053 13.0 0.0 2.1 1 1 1 2 2 2 1 Ubiquitin fusion degradation protein UFD1 NB-ARC PF00931.22 KXL48171.1 - 0.0047 16.1 0.0 1.5 7.9 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain KAP_NTPase PF07693.14 KXL48171.1 - 0.0062 15.8 0.3 0.93 8.7 0.0 3.3 2 2 2 4 4 4 1 KAP family P-loop domain Sigma54_activ_2 PF14532.6 KXL48171.1 - 0.0087 16.2 0.0 1.5 9.0 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Viral_helicase1 PF01443.18 KXL48171.1 - 0.01 15.6 0.0 0.67 9.6 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 KXL48171.1 - 0.011 15.7 0.4 4.1 7.3 0.0 3.5 3 0 0 3 3 3 0 NTPase IPT PF01745.16 KXL48171.1 - 0.025 14.0 0.0 1.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Zot PF05707.12 KXL48171.1 - 0.027 14.1 0.1 2.8 7.5 0.0 3.5 2 2 0 2 2 2 0 Zonular occludens toxin (Zot) Zeta_toxin PF06414.12 KXL48171.1 - 0.032 13.5 0.3 10 5.3 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin Cytidylate_kin PF02224.18 KXL48171.1 - 0.077 12.7 0.0 18 5.0 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase AAA_6 PF12774.7 KXL48171.1 - 0.093 11.7 0.2 9.7 5.1 0.0 2.5 3 0 0 3 3 2 0 Hydrolytic ATP binding site of dynein motor region eIF-1a PF01176.19 KXL48171.1 - 0.13 12.1 1.3 0.59 10.0 0.3 2.4 1 1 1 2 2 2 0 Translation initiation factor 1A / IF-1 TRAP_alpha PF03896.16 KXL48172.1 - 2.9e-14 52.9 0.3 2.3e-13 50.0 0.3 1.9 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit UQ_con PF00179.26 KXL48173.1 - 1.8e-20 73.0 0.0 3e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pex14_N PF04695.13 KXL48173.1 - 0.028 15.1 1.0 0.05 14.3 1.0 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-MIZ PF02891.20 KXL48173.1 - 0.059 13.1 0.3 0.13 12.0 0.3 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger RWD PF05773.22 KXL48173.1 - 0.12 12.6 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 RWD domain FAM76 PF16046.5 KXL48173.1 - 0.18 11.1 1.3 0.28 10.5 1.3 1.3 1 0 0 1 1 1 0 FAM76 protein DNA_ligase_ZBD PF03119.16 KXL48173.1 - 1.1 9.3 3.3 1.8 8.7 2.1 2.0 2 1 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Cupin_8 PF13621.6 KXL48174.1 - 1.5e-70 237.8 0.9 2e-70 237.4 0.9 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KXL48174.1 - 5e-05 22.9 0.0 0.014 14.8 0.0 2.4 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 KXL48174.1 - 0.012 16.0 0.1 0.46 10.9 0.0 3.0 2 2 0 2 2 2 0 JmjC domain, hydroxylase PAS_11 PF14598.6 KXL48174.1 - 0.13 12.4 0.0 1.6 8.9 0.0 2.4 1 1 1 2 2 2 0 PAS domain Patatin PF01734.22 KXL48175.1 - 8.2e-23 81.7 0.1 1.7e-22 80.6 0.1 1.5 1 1 0 1 1 1 1 Patatin-like phospholipase ADH_N PF08240.12 KXL48176.1 - 8.1e-17 61.1 0.0 1.5e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXL48176.1 - 1.4e-12 47.7 0.1 2.1e-12 47.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KXL48176.1 - 0.0018 17.7 1.8 0.0042 16.6 1.8 1.6 1 1 0 1 1 1 1 short chain dehydrogenase PRMT5 PF05185.16 KXL48176.1 - 0.035 14.0 0.1 0.057 13.3 0.1 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_32 PF13679.6 KXL48176.1 - 0.069 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain 3HCDH_N PF02737.18 KXL48176.1 - 0.2 11.5 1.9 0.79 9.6 2.1 1.8 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_hydro_7 PF00840.20 KXL48177.1 - 8.7e-151 502.5 6.0 1.1e-150 502.2 6.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Ectatomin PF06457.11 KXL48177.1 - 0.032 14.1 0.2 0.075 13.0 0.2 1.6 1 0 0 1 1 1 0 Ectatomin TauD PF02668.16 KXL48178.1 - 7.3e-55 186.6 0.0 8.4e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sulfatase PF00884.23 KXL48179.1 - 5.9e-44 150.7 1.0 1.3e-42 146.3 0.1 2.4 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 KXL48179.1 - 2.3e-08 34.0 0.1 1.6e-07 31.3 0.1 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 KXL48179.1 - 0.0014 18.9 1.4 0.0036 17.5 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) Sulfatase_C PF14707.6 KXL48179.1 - 0.0035 18.1 0.0 0.0087 16.8 0.0 1.7 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF5098 PF17023.5 KXL48179.1 - 0.079 11.9 0.1 0.16 10.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5098) SNF2_N PF00176.23 KXL48180.1 - 6.4e-71 238.9 0.0 9.5e-71 238.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KXL48180.1 - 3.3e-23 81.4 0.0 6.6e-23 80.5 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 KXL48180.1 - 7.4e-17 61.7 0.0 1.7e-16 60.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL48180.1 - 0.00011 22.3 0.0 0.00029 20.9 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KXL48180.1 - 0.00011 22.0 0.0 0.00027 20.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.25 KXL48180.1 - 0.00015 21.6 7.9 0.00031 20.6 7.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXL48180.1 - 0.00034 20.4 4.7 0.00072 19.3 4.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXL48180.1 - 0.00078 19.3 5.8 0.0015 18.3 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXL48180.1 - 0.0015 18.9 8.3 0.0038 17.5 8.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KXL48180.1 - 0.013 15.5 7.9 0.026 14.5 7.9 1.6 1 0 0 1 1 1 0 RING-type zinc-finger ERCC3_RAD25_C PF16203.5 KXL48180.1 - 0.013 14.7 0.1 0.023 13.9 0.1 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase UBA_4 PF14555.6 KXL48180.1 - 0.032 14.0 0.2 0.093 12.6 0.1 1.8 2 0 0 2 2 2 0 UBA-like domain zf-RING_5 PF14634.6 KXL48180.1 - 0.079 12.9 7.1 0.4 10.7 7.5 2.0 1 1 1 2 2 2 0 zinc-RING finger domain DNA_pol_B PF00136.21 KXL48181.1 - 7.3e-145 483.2 2.8 1.1e-144 482.6 2.8 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KXL48181.1 - 1.6e-82 277.4 0.1 2.6e-82 276.6 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KXL48181.1 - 3.8e-17 62.5 0.9 9.3e-17 61.3 0.9 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.9 KXL48181.1 - 0.00031 20.5 0.0 0.00066 19.4 0.0 1.5 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_2 PF03175.13 KXL48181.1 - 0.0042 16.0 0.6 0.041 12.8 0.0 2.4 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral ORC6 PF05460.13 KXL48181.1 - 0.061 12.6 1.1 0.11 11.7 1.1 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Homeodomain PF00046.29 KXL48183.1 - 3e-19 68.6 4.1 6.4e-19 67.6 4.1 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KXL48183.1 - 0.025 14.5 0.5 0.055 13.4 0.5 1.6 1 0 0 1 1 1 0 Homeobox KN domain Sugar_tr PF00083.24 KXL48184.1 - 3.1e-111 372.4 26.9 3.7e-111 372.2 26.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL48184.1 - 8.7e-27 94.0 50.4 2.7e-25 89.0 30.7 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXL48184.1 - 5.1e-05 21.9 1.7 0.00011 20.8 1.7 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 KXL48184.1 - 8.9e-05 21.6 1.3 0.00022 20.3 1.3 1.6 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM DUF2530 PF10745.9 KXL48184.1 - 3.4 8.0 7.0 1.6 9.0 2.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Sdh5 PF03937.16 KXL48185.1 - 1.3e-23 82.7 0.2 5.4e-23 80.7 0.2 1.9 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase Hydantoinase_B PF02538.14 KXL48186.1 - 3.3e-125 418.4 0.0 5e-125 417.8 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KXL48186.1 - 1.4e-87 293.7 2.4 4.6e-87 292.0 1.3 2.1 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KXL48186.1 - 1.2e-45 155.4 0.1 1e-42 145.9 0.0 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 KXL48186.1 - 5.5e-06 25.3 0.2 0.0044 15.7 0.1 2.4 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.20 KXL48186.1 - 0.0071 15.9 0.3 0.26 10.8 0.0 2.3 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.6 KXL48186.1 - 0.16 12.4 0.2 26 5.3 0.0 2.8 2 0 0 2 2 2 0 Cell division protein FtsA Ppx-GppA PF02541.16 KXL48186.1 - 0.19 11.2 0.2 0.35 10.2 0.2 1.4 1 0 0 1 1 1 0 Ppx/GppA phosphatase family SRR1 PF07985.12 KXL48187.1 - 4.1e-11 42.8 0.0 7.3e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 SRR1 Clathrin_bdg PF15045.6 KXL48187.1 - 0.032 14.2 0.1 0.07 13.1 0.1 1.6 1 0 0 1 1 1 0 Clathrin-binding box of Aftiphilin, vesicle trafficking Sugar_tr PF00083.24 KXL48188.1 - 2.9e-73 247.3 23.8 3.4e-73 247.0 23.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL48188.1 - 3e-20 72.5 33.3 5.2e-14 51.9 13.6 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXL48188.1 - 0.72 8.6 14.3 0.012 14.5 3.5 2.7 2 1 0 2 2 2 0 MFS_1 like family Phage_holin_7_1 PF16081.5 KXL48188.1 - 4.7 7.4 5.3 0.88 9.7 0.5 2.2 3 0 0 3 3 3 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family zf-ISL3 PF14690.6 KXL48189.1 - 0.081 13.6 3.2 9 7.0 0.1 2.6 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Glyco_transf_34 PF05637.12 KXL48190.1 - 1.2e-62 211.7 0.0 1.4e-62 211.5 0.0 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF3645 PF12359.8 KXL48190.1 - 0.17 11.3 0.9 0.36 10.2 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3645) MMR_HSR1 PF01926.23 KXL48191.1 - 0.00026 21.1 0.0 0.0027 17.8 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase HIP1_clath_bdg PF16515.5 KXL48192.1 - 0.019 15.6 8.0 0.023 15.3 8.0 1.0 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Pterin_4a PF01329.19 KXL48192.1 - 0.052 13.7 0.0 0.056 13.6 0.0 1.1 1 0 0 1 1 1 0 Pterin 4 alpha carbinolamine dehydratase TPX2 PF06886.11 KXL48192.1 - 0.82 9.9 19.0 1.8 8.8 3.0 2.2 1 1 1 2 2 2 0 Targeting protein for Xklp2 (TPX2) DUF3328 PF11807.8 KXL48194.1 - 4.5e-37 127.9 2.3 5.3e-37 127.7 2.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 KXL48195.1 - 1.7e-49 168.6 1.0 2.1e-49 168.3 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Asp PF00026.23 KXL48196.1 - 2.6e-64 217.6 0.4 3e-64 217.4 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXL48196.1 - 4.4e-11 43.4 0.9 0.00087 19.6 0.1 3.9 2 2 2 4 4 4 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KXL48196.1 - 5.3e-05 23.8 0.1 0.024 15.3 0.1 2.9 2 1 0 2 2 2 2 Aspartyl protease EF-hand_1 PF00036.32 KXL48198.1 - 1.7e-24 83.5 7.1 7.1e-08 31.5 0.1 4.8 6 0 0 6 6 6 3 EF hand EF-hand_7 PF13499.6 KXL48198.1 - 3.4e-24 85.1 4.1 4.6e-15 55.8 0.4 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KXL48198.1 - 2e-23 80.2 2.8 2.3e-06 27.1 0.1 5.3 4 1 1 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 KXL48198.1 - 2.4e-16 58.4 9.8 0.00013 21.3 0.0 4.9 6 0 0 6 6 6 3 EF hand EF-hand_8 PF13833.6 KXL48198.1 - 1.1e-15 57.2 10.0 1.5e-05 24.7 0.2 4.0 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 KXL48198.1 - 6e-09 35.8 4.6 0.0032 17.4 0.1 3.8 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KXL48198.1 - 0.00071 19.9 0.2 0.033 14.5 0.1 3.0 2 1 1 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.9 KXL48198.1 - 0.0069 16.7 2.2 0.77 10.1 0.1 3.4 1 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 KXL48198.1 - 0.17 11.7 2.7 1.7 8.6 0.0 3.5 4 1 0 4 4 4 0 EF hand NIF3 PF01784.18 KXL48199.1 - 3.1e-62 210.4 0.0 4.1e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) DUF5546 PF17700.1 KXL48199.1 - 0.33 11.3 1.8 0.57 10.5 1.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5546) BolA PF01722.18 KXL48200.1 - 6.8e-17 61.5 0.0 2e-16 60.0 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein 2OG-FeII_Oxy PF03171.20 KXL48201.1 - 4.5e-15 56.0 0.0 8.7e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KXL48201.1 - 3.2e-13 50.5 0.1 6.6e-13 49.4 0.1 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal ADH_zinc_N PF00107.26 KXL48202.1 - 1.5e-27 96.1 0.2 1.5e-27 96.1 0.2 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXL48202.1 - 5e-20 71.4 2.2 1.3e-19 70.1 2.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KXL48202.1 - 0.013 15.0 1.2 0.034 13.6 0.7 1.9 1 1 1 2 2 2 0 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 KXL48202.1 - 0.072 14.1 0.0 0.12 13.5 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXL48202.1 - 0.075 12.3 0.4 0.11 11.7 0.4 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SCAB-ABD PF16711.5 KXL48203.1 - 0.03 14.2 0.2 0.034 14.1 0.2 1.2 1 0 0 1 1 1 0 Actin-binding domain of plant-specific actin-binding protein FtsJ PF01728.19 KXL48204.1 - 4.7e-63 212.5 0.0 6e-63 212.1 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase BORCS6 PF10157.9 KXL48206.1 - 0.08 13.2 0.2 0.12 12.6 0.2 1.1 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 6 FAD_binding_3 PF01494.19 KXL48207.1 - 1.2e-10 41.2 0.0 2.7e-10 40.0 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXL48207.1 - 0.00038 20.6 0.0 0.00089 19.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXL48207.1 - 0.00085 19.0 0.1 0.0015 18.2 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXL48207.1 - 0.021 14.1 0.4 2 7.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXL48207.1 - 0.023 15.2 0.3 1.5 9.4 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXL48207.1 - 0.068 13.2 0.1 0.84 9.6 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KXL48207.1 - 0.08 11.8 0.2 0.8 8.5 0.0 2.3 3 0 0 3 3 3 0 Tryptophan halogenase HetR_C PF18460.1 KXL48207.1 - 0.15 12.0 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 Heterocyst differentiation regulator C-terminal Hood domain p450 PF00067.22 KXL48209.1 - 2.4e-42 145.3 0.0 2.1e-41 142.1 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 AA_permease PF00324.21 KXL48210.1 - 8.7e-140 466.5 43.9 1e-139 466.3 43.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXL48210.1 - 6.7e-36 124.0 47.9 8.6e-36 123.7 47.9 1.0 1 0 0 1 1 1 1 Amino acid permease Mid2 PF04478.12 KXL48211.1 - 0.02 14.8 0.1 0.073 12.9 0.1 2.0 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor DUF3546 PF12066.8 KXL48212.1 - 0.041 14.1 0.0 0.044 14.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3546) TRAF_BIRC3_bd PF16673.5 KXL48212.1 - 0.14 12.0 0.2 0.28 11.0 0.2 1.6 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain Ysc84 PF04366.12 KXL48213.1 - 9.3e-40 135.3 0.4 1.4e-39 134.7 0.4 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 KXL48213.1 - 5.9e-14 51.4 0.5 1.2e-13 50.4 0.1 1.7 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KXL48213.1 - 2e-12 46.6 0.0 4.6e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KXL48213.1 - 4e-10 39.4 0.0 7.6e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain BUD22 PF09073.10 KXL48214.1 - 3.5e-83 280.3 11.2 4.2e-83 280.1 11.2 1.1 1 0 0 1 1 1 1 BUD22 RTA1 PF04479.13 KXL48215.1 - 3e-56 190.3 6.3 3e-56 190.3 6.3 1.6 1 1 1 2 2 2 1 RTA1 like protein Zn_clus PF00172.18 KXL48216.1 - 4.1e-08 33.2 9.0 6.7e-08 32.5 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXL48216.1 - 0.00057 18.8 0.1 0.00082 18.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain LPD3 PF18798.1 KXL48216.1 - 0.0044 17.3 0.0 0.0077 16.5 0.0 1.3 1 0 0 1 1 1 1 Large polyvalent protein-associated domain 3 DUF2797 PF10977.8 KXL48216.1 - 0.054 13.4 0.4 0.096 12.6 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) zf-RING_2 PF13639.6 KXL48217.1 - 2.1e-09 37.6 3.5 3e-09 37.0 3.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KXL48217.1 - 1.9e-06 28.0 6.1 6.5e-06 26.3 1.0 2.3 1 1 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KXL48217.1 - 0.00013 21.9 0.6 0.00021 21.3 0.6 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KXL48217.1 - 0.00058 19.8 6.2 0.00096 19.1 6.2 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXL48217.1 - 0.0051 16.6 5.7 0.021 14.7 5.8 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 KXL48217.1 - 0.012 15.8 0.0 0.032 14.5 0.0 1.7 1 0 0 1 1 1 0 zinc-ribbon zf-RING_11 PF17123.5 KXL48217.1 - 0.033 13.9 3.7 0.054 13.3 3.7 1.4 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_3 PF13920.6 KXL48217.1 - 0.037 13.9 1.4 0.12 12.3 1.3 1.7 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXL48217.1 - 0.063 13.2 0.9 0.13 12.1 0.9 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXL48217.1 - 0.1 12.6 1.4 0.46 10.5 1.3 1.9 1 1 1 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KXL48217.1 - 0.15 11.9 5.1 3 7.8 0.6 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DUF747 PF05346.11 KXL48218.1 - 7.5e-124 413.3 6.9 9.4e-124 413.0 6.9 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family Asparaginase_2 PF01112.18 KXL48219.1 - 1.2e-57 195.3 0.5 8.5e-52 176.1 0.0 2.8 2 1 0 2 2 2 2 Asparaginase Asp PF00026.23 KXL48222.1 - 1.2e-09 38.1 0.0 1.5e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Adeno_E3_CR2 PF02439.15 KXL48222.1 - 0.0095 15.7 0.8 0.017 14.9 0.8 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF4328 PF14219.6 KXL48222.1 - 0.041 13.4 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) VSP PF03302.13 KXL48222.1 - 0.13 11.1 0.6 0.2 10.5 0.6 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein SKG6 PF08693.10 KXL48222.1 - 0.34 10.3 6.3 0.63 9.5 6.3 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain cNMP_binding PF00027.29 KXL48223.1 - 2.8e-40 136.3 0.0 1.7e-19 69.7 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 KXL48223.1 - 8.1e-10 38.2 0.8 1.5e-09 37.3 0.8 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit YscJ_FliF PF01514.17 KXL48223.1 - 0.093 12.4 0.0 0.96 9.1 0.0 2.0 2 0 0 2 2 2 0 Secretory protein of YscJ/FliF family Response_reg PF00072.24 KXL48226.1 - 1.7e-26 92.6 0.2 3e-26 91.8 0.2 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 KXL48226.1 - 5.5e-24 84.8 0.0 3.7e-23 82.2 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KXL48226.1 - 1.4e-15 57.1 0.0 4.5e-15 55.4 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain dCache_1 PF02743.18 KXL48226.1 - 0.15 11.8 5.6 1.6 8.5 5.6 2.3 1 1 0 1 1 1 0 Cache domain FtsX PF02687.21 KXL48226.1 - 0.17 12.4 1.6 2.6 8.5 0.5 2.4 2 0 0 2 2 2 0 FtsX-like permease family HAMP PF00672.25 KXL48226.1 - 0.57 10.6 8.3 0.44 11.0 0.1 3.4 3 0 0 3 3 3 0 HAMP domain PTPA PF03095.15 KXL48228.1 - 7.4e-116 386.8 0.0 8.6e-116 386.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein NicO PF03824.16 KXL48230.1 - 0.15 11.4 0.1 0.21 10.9 0.1 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein AA_permease PF00324.21 KXL48231.1 - 1.3e-124 416.4 42.8 1.6e-124 416.1 42.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXL48231.1 - 9.8e-29 100.4 45.1 1.3e-28 100.0 45.1 1.1 1 0 0 1 1 1 1 Amino acid permease Methyltransf_11 PF08241.12 KXL48233.1 - 3.2e-23 82.2 0.0 5.6e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL48233.1 - 3.4e-23 82.2 0.0 1.2e-22 80.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL48233.1 - 3.4e-22 78.9 0.0 4.9e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXL48233.1 - 4.4e-16 58.9 0.0 6.5e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KXL48233.1 - 1.1e-15 58.2 0.0 1.6e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXL48233.1 - 7.9e-15 55.1 0.0 1.2e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXL48233.1 - 1.2e-08 34.7 0.0 2.1e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KXL48233.1 - 2.2e-06 27.6 0.0 3.2e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KXL48233.1 - 0.00011 21.7 0.0 0.00017 21.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 KXL48233.1 - 0.00013 21.4 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain DREV PF05219.12 KXL48233.1 - 0.00014 21.0 0.0 0.00024 20.3 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase MetW PF07021.12 KXL48233.1 - 0.00032 20.3 0.0 0.00066 19.3 0.0 1.5 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_16 PF10294.9 KXL48233.1 - 0.00064 19.5 0.0 0.00098 18.9 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_4 PF02390.17 KXL48233.1 - 0.001 18.6 0.0 0.0021 17.5 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.6 KXL48233.1 - 0.0018 18.3 0.0 0.0026 17.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 KXL48233.1 - 0.0024 16.5 0.0 0.0034 16.0 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_18 PF12847.7 KXL48233.1 - 0.0031 17.4 0.0 0.0057 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 KXL48233.1 - 0.0036 17.1 0.0 0.0062 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) GCD14 PF08704.10 KXL48233.1 - 0.0076 16.0 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit CheR PF01739.18 KXL48233.1 - 0.015 14.8 0.0 0.85 9.1 0.0 2.4 2 1 1 3 3 3 0 CheR methyltransferase, SAM binding domain CMAS PF02353.20 KXL48233.1 - 0.066 12.5 0.0 0.095 12.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase RrnaAD PF00398.20 KXL48233.1 - 0.084 11.9 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Cytochrom_C1 PF02167.15 KXL48234.1 - 5.7e-94 313.9 0.0 7.1e-94 313.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 KXL48234.1 - 0.0088 16.4 0.0 0.021 15.1 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 KXL48234.1 - 0.033 15.3 0.1 0.38 11.9 0.0 2.7 3 0 0 3 3 3 0 Cytochrome c HTH_Tnp_Tc5 PF03221.16 KXL48238.1 - 1.6e-05 24.9 0.0 1.8e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Mito_carr PF00153.27 KXL48239.1 - 1.7e-05 24.6 0.0 0.21 11.5 0.0 2.1 1 1 1 2 2 2 2 Mitochondrial carrier protein SPOUT_MTase_2 PF14419.6 KXL48239.1 - 0.15 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP Pro-kuma_activ PF09286.11 KXL48240.1 - 1.4e-41 142.1 0.0 2.2e-41 141.4 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KXL48240.1 - 0.037 13.3 0.2 0.062 12.5 0.2 1.3 1 0 0 1 1 1 0 Subtilase family DUF1772 PF08592.11 KXL48241.1 - 5.5e-23 81.8 1.6 6.4e-23 81.6 1.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) HTH_psq PF05225.16 KXL48242.1 - 1.5e-05 24.6 0.6 2.4e-05 24.0 0.6 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.16 KXL48242.1 - 0.0004 20.4 0.0 0.00074 19.5 0.0 1.5 1 1 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 KXL48243.1 - 1.3e-05 24.9 0.2 1.9e-05 24.3 0.2 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.16 KXL48243.1 - 0.00016 21.6 0.0 0.00025 21.0 0.0 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KXL48243.1 - 0.068 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain NAD_binding_4 PF07993.12 KXL48244.1 - 2.5e-33 115.3 0.0 3.8e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KXL48244.1 - 2.8e-25 88.8 0.0 4.2e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KXL48244.1 - 6.3e-09 35.6 0.0 1.1e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KXL48244.1 - 7e-07 29.5 0.0 1.9e-06 28.1 0.0 1.8 1 1 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 KXL48244.1 - 0.0094 15.0 0.0 0.03 13.3 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KXL48244.1 - 0.18 10.9 0.0 5.6 6.0 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain RPN5_C PF18098.1 KXL48244.1 - 1.7 8.8 7.9 2.8 8.1 1.4 3.4 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN5 C-terminal domain GFO_IDH_MocA PF01408.22 KXL48245.1 - 1.2e-24 87.4 0.0 2.2e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 KXL48245.1 - 0.00024 21.2 0.0 0.015 15.4 0.0 2.5 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA_C PF02894.17 KXL48245.1 - 0.0012 18.8 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Gp_dh_N PF00044.24 KXL48245.1 - 0.15 12.4 0.2 0.5 10.7 0.1 1.8 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.8 KXL48246.1 - 1.9e-05 23.7 0.0 3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 KXL48247.1 - 2.9e-47 161.6 18.4 4.4e-47 161.0 18.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL48247.1 - 1.6e-13 50.3 21.4 1.6e-13 50.3 21.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3388 PF11868.8 KXL48247.1 - 0.094 12.0 0.2 0.18 11.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3388) HAD_2 PF13419.6 KXL48250.1 - 2.1e-05 24.7 0.0 3.4e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXL48250.1 - 0.02 14.9 0.0 0.039 14.0 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Aminotran_5 PF00266.19 KXL48252.1 - 8e-14 51.4 0.0 6.4e-10 38.5 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Aminotran_1_2 PF00155.21 KXL48252.1 - 0.073 12.2 0.0 8 5.5 0.0 2.2 1 1 1 2 2 2 0 Aminotransferase class I and II GP46 PF07409.12 KXL48253.1 - 0.088 12.6 0.2 0.18 11.6 0.1 1.6 1 1 0 1 1 1 0 Phage protein GP46 FSH1 PF03959.13 KXL48254.1 - 0.16 11.6 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Ank_2 PF12796.7 KXL48255.1 - 5.5e-16 58.9 0.1 8.6e-06 26.3 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXL48255.1 - 2.4e-11 43.9 0.2 8.4e-06 26.2 0.0 3.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KXL48255.1 - 1.5e-10 41.0 0.0 0.0011 19.3 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KXL48255.1 - 1.9e-09 37.6 0.3 0.0013 19.0 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXL48255.1 - 2.4e-08 33.6 0.1 0.016 15.7 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.13 KXL48255.1 - 2.3e-05 24.2 0.1 9.6e-05 22.2 0.1 1.9 1 1 0 1 1 1 1 KilA-N domain IGPS PF00218.21 KXL48256.1 - 1.4e-97 325.8 0.0 4.2e-97 324.3 0.0 1.7 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 KXL48256.1 - 9.2e-51 172.4 0.0 1.6e-46 158.6 0.0 2.3 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 KXL48256.1 - 4e-45 153.9 0.0 6.9e-45 153.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KXL48256.1 - 1.8e-05 24.6 0.2 8.7e-05 22.4 0.2 2.1 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 KXL48256.1 - 0.0014 18.4 1.1 0.12 12.1 0.1 3.1 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain Aldolase PF01081.19 KXL48256.1 - 0.078 12.4 0.1 2 7.8 0.0 2.8 3 0 0 3 3 3 0 KDPG and KHG aldolase NDUF_B7 PF05676.13 KXL48257.1 - 4.8e-30 103.1 7.4 5.7e-30 102.8 7.4 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 KXL48257.1 - 0.041 13.9 2.5 0.053 13.6 2.5 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pro-kuma_activ PF09286.11 KXL48259.1 - 1e-25 90.7 0.0 2.5e-15 57.0 0.0 2.8 2 1 1 3 3 3 2 Pro-kumamolisin, activation domain Sugar_tr PF00083.24 KXL48260.1 - 4.5e-104 348.8 21.5 5.3e-104 348.6 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL48260.1 - 3e-27 95.5 52.5 3e-21 75.7 25.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3623 PF12291.8 KXL48260.1 - 0.007 15.6 3.0 0.01 15.1 0.4 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF3623) TRI12 PF06609.13 KXL48260.1 - 0.013 14.0 6.1 0.0069 14.9 2.2 2.2 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Iron_permease PF04120.12 KXL48261.1 - 5e-31 107.1 24.2 8.5e-10 38.5 4.3 4.1 3 1 1 4 4 4 4 Low affinity iron permease HTH_psq PF05225.16 KXL48262.1 - 0.0012 18.6 0.2 0.0019 17.9 0.2 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain SpoIIID PF12116.8 KXL48262.1 - 0.032 14.3 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 Stage III sporulation protein D HTH_Tnp_Tc5 PF03221.16 KXL48262.1 - 0.051 13.6 0.1 0.12 12.4 0.1 1.7 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain Aldo_ket_red PF00248.21 KXL48263.1 - 1.3e-75 254.4 0.0 1.4e-75 254.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LacI PF00356.21 KXL48263.1 - 0.0002 21.1 0.2 0.00049 19.8 0.2 1.7 1 1 0 1 1 1 1 Bacterial regulatory proteins, lacI family Ank_4 PF13637.6 KXL48263.1 - 0.055 14.1 0.0 4.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) RGS PF00615.19 KXL48265.1 - 3.5e-30 104.7 0.1 9e-30 103.4 0.0 1.7 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 KXL48265.1 - 3.4e-19 68.7 0.1 2e-13 50.2 0.0 3.4 3 0 0 3 3 3 3 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Peptidase_M24 PF00557.24 KXL48266.1 - 1e-43 149.5 0.1 1.3e-43 149.1 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Pectinesterase PF01095.19 KXL48266.1 - 0.00022 20.1 0.0 0.00036 19.3 0.0 1.2 1 0 0 1 1 1 1 Pectinesterase YL1 PF05764.13 KXL48266.1 - 0.03 14.4 6.3 0.045 13.9 6.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein NST1 PF13945.6 KXL48266.1 - 0.078 13.1 2.2 0.12 12.4 2.2 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator VSG_B PF13206.6 KXL48266.1 - 0.16 11.2 3.3 0.24 10.6 3.3 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain TFIIF_alpha PF05793.12 KXL48266.1 - 0.19 10.3 9.2 0.28 9.8 9.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RNA_polI_A34 PF08208.11 KXL48266.1 - 0.51 10.4 9.7 0.91 9.6 9.7 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CDC45 PF02724.14 KXL48266.1 - 0.57 8.4 6.5 0.83 7.9 6.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3405 PF11885.8 KXL48267.1 - 8.2e-227 753.9 6.8 1.1e-226 753.5 6.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) WavE PF07507.11 KXL48267.1 - 0.052 12.7 0.0 0.08 12.1 0.0 1.3 1 0 0 1 1 1 0 WavE lipopolysaccharide synthesis TatD_DNase PF01026.21 KXL48268.1 - 5.6e-51 173.4 0.0 7.1e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Prefoldin_3 PF13758.6 KXL48270.1 - 4.5e-19 68.3 0.8 4.5e-19 68.3 0.8 2.3 2 0 0 2 2 2 1 Prefoldin subunit DUF3835 PF12927.7 KXL48270.1 - 5.3e-17 62.4 1.3 5.3e-17 62.4 1.3 4.4 4 0 0 4 4 4 1 Domain of unknown function (DUF3835) FRG2 PF15315.6 KXL48270.1 - 0.035 14.3 0.4 0.37 11.0 0.0 2.6 2 0 0 2 2 2 0 Facioscapulohumeral muscular dystrophy candidate 2 Prefoldin_2 PF01920.20 KXL48270.1 - 0.036 14.0 1.6 12 5.9 0.0 3.0 2 0 0 2 2 2 0 Prefoldin subunit YqjK PF13997.6 KXL48270.1 - 0.099 12.9 1.7 0.22 11.8 1.7 1.5 1 0 0 1 1 1 0 YqjK-like protein Tim17 PF02466.19 KXL48271.1 - 2.6e-33 114.7 7.5 3.3e-33 114.4 7.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Phage_holin_3_3 PF16083.5 KXL48271.1 - 0.11 12.6 0.4 0.11 12.6 0.4 2.3 2 0 0 2 2 2 0 LydA holin phage, holin superfamily III HATPase_c_4 PF13749.6 KXL48271.1 - 0.22 11.7 0.0 0.42 10.8 0.0 1.5 1 1 0 1 1 1 0 Putative ATP-dependent DNA helicase recG C-terminal PsaL PF02605.15 KXL48271.1 - 2 8.1 4.5 17 5.0 1.2 2.2 2 0 0 2 2 2 0 Photosystem I reaction centre subunit XI MAT1 PF06391.13 KXL48272.1 - 1.5e-46 158.9 15.3 1.8e-46 158.5 15.3 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 KXL48272.1 - 4.5e-15 55.3 6.1 7.4e-15 54.6 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXL48272.1 - 0.0015 18.3 3.0 0.0026 17.5 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXL48272.1 - 0.0021 17.9 2.9 0.0037 17.1 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KXL48272.1 - 0.0031 17.1 1.0 0.0048 16.5 1.0 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KXL48272.1 - 0.0039 17.1 5.0 0.0069 16.3 5.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXL48272.1 - 0.055 13.3 3.9 0.082 12.8 3.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXL48272.1 - 0.064 13.3 3.6 0.12 12.4 3.6 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.6 KXL48272.1 - 0.23 11.3 3.5 0.48 10.3 3.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KXL48272.1 - 0.3 11.0 4.0 0.58 10.1 4.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KXL48272.1 - 0.32 11.4 5.1 0.52 10.7 5.1 1.3 1 0 0 1 1 1 0 Ring finger domain Glyco_hydro_64 PF16483.5 KXL48273.1 - 6.3e-135 450.2 1.9 7.3e-135 450.0 1.9 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase DUF916 PF06030.12 KXL48273.1 - 0.026 14.6 0.5 0.19 11.8 0.2 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF916) TSC22 PF01166.18 KXL48274.1 - 0.05 13.9 0.7 0.1 12.9 0.2 1.7 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF572 PF04502.13 KXL48275.1 - 5.7e-60 203.7 0.5 6.7e-60 203.5 0.5 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-C2H2_2 PF12756.7 KXL48276.1 - 4e-31 107.3 23.8 4.1e-30 104.1 1.4 3.7 4 0 0 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KXL48276.1 - 6e-08 32.8 23.8 4e-05 23.8 4.3 4.1 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXL48276.1 - 1e-06 28.9 10.4 1.4e-05 25.3 4.0 3.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type DUF629 PF04780.12 KXL48276.1 - 0.018 13.6 1.9 1.2 7.6 0.5 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF629) AA_permease PF00324.21 KXL48279.1 - 4.7e-96 322.3 40.9 5.6e-96 322.0 40.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXL48279.1 - 1.2e-17 63.9 41.8 1.6e-17 63.5 41.8 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3671 PF12420.8 KXL48279.1 - 4.9 7.3 6.6 67 3.6 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function Abhydrolase_1 PF00561.20 KXL48280.1 - 4.6e-11 42.9 0.1 7.8e-11 42.1 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXL48280.1 - 1.2e-09 39.1 0.1 2.4e-09 38.2 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXL48280.1 - 8.4e-09 35.0 0.0 1.2e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 ABC_tran PF00005.27 KXL48282.1 - 4.5e-46 156.8 0.0 3e-29 102.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXL48282.1 - 5.3e-34 118.1 45.9 4.7e-20 72.4 20.9 4.3 4 0 0 4 4 4 3 ABC transporter transmembrane region SMC_N PF02463.19 KXL48282.1 - 5e-13 49.0 0.6 2.2e-05 24.0 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXL48282.1 - 2.1e-06 27.4 0.9 0.00079 19.1 0.4 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KXL48282.1 - 2.6e-06 27.7 0.1 0.14 12.5 0.1 3.0 2 1 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KXL48282.1 - 5.5e-06 26.4 0.2 0.42 10.4 0.0 4.2 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KXL48282.1 - 7.1e-05 23.4 0.4 0.043 14.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KXL48282.1 - 0.00093 19.0 0.0 0.14 11.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 KXL48282.1 - 0.0039 17.6 0.0 1.5 9.2 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KXL48282.1 - 0.0049 16.2 0.3 0.78 9.0 0.2 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family T2SSE PF00437.20 KXL48282.1 - 0.0067 15.5 0.0 1 8.4 0.1 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 KXL48282.1 - 0.011 15.4 1.5 0.35 10.6 0.0 2.8 3 0 0 3 3 2 0 IstB-like ATP binding protein AAA_25 PF13481.6 KXL48282.1 - 0.015 14.9 0.4 0.081 12.5 0.1 2.2 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KXL48282.1 - 0.027 14.5 0.8 0.058 13.5 0.8 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain Dynamin_N PF00350.23 KXL48282.1 - 0.033 14.3 0.2 3.4 7.7 0.0 2.6 2 0 0 2 2 2 0 Dynamin family SbcCD_C PF13558.6 KXL48282.1 - 0.054 13.7 0.0 8.5 6.7 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 KXL48282.1 - 0.058 13.6 0.1 12 6.0 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 KXL48282.1 - 0.059 13.8 0.0 0.96 9.9 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KXL48282.1 - 0.091 12.9 0.1 1.9 8.6 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Pox_A32 PF04665.12 KXL48282.1 - 0.11 11.9 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein DOT1 PF08123.13 KXL48284.1 - 5.3e-67 225.3 0.0 7.9e-67 224.8 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 DUF4942 PF13708.6 KXL48284.1 - 0.066 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4942) Methyltransf_25 PF13649.6 KXL48284.1 - 0.11 13.2 0.0 0.27 11.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Lon_C PF05362.13 KXL48284.1 - 0.16 11.5 0.2 0.3 10.6 0.2 1.3 1 0 0 1 1 1 0 Lon protease (S16) C-terminal proteolytic domain JHBP PF06585.11 KXL48285.1 - 0.18 11.0 0.0 0.31 10.2 0.0 1.4 1 1 0 1 1 1 0 Haemolymph juvenile hormone binding protein (JHBP) FAD_binding_4 PF01565.23 KXL48286.1 - 2.7e-19 69.3 1.0 5.7e-19 68.2 1.0 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXL48286.1 - 7.4e-09 35.6 0.2 1.6e-08 34.5 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like Glyco_hydro_16 PF00722.21 KXL48288.1 - 6.7e-15 55.0 0.0 1.1e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 EF-hand_4 PF12763.7 KXL48289.1 - 1e-05 25.4 0.1 2e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KXL48289.1 - 0.058 13.0 0.1 0.098 12.2 0.1 1.4 1 0 0 1 1 1 0 EF hand DNA_ligase_A_M PF01068.21 KXL48290.1 - 1e-47 162.5 0.7 7.3e-47 159.7 0.0 2.5 3 0 0 3 3 3 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KXL48290.1 - 5.6e-43 147.3 0.0 1.5e-42 145.9 0.0 1.8 1 0 0 1 1 1 1 DNA ligase N terminus BRCT_2 PF16589.5 KXL48290.1 - 2.6e-22 79.0 0.0 1.4e-13 51.0 0.0 3.0 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 KXL48290.1 - 6.6e-17 61.9 0.1 2e-16 60.4 0.1 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KXL48290.1 - 5.1e-15 56.1 0.0 1.6e-14 54.5 0.0 1.9 2 0 0 2 2 2 1 RNA ligase BRCT PF00533.26 KXL48290.1 - 1.8e-08 34.7 0.0 0.00036 20.9 0.0 3.0 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KXL48290.1 - 6.1e-07 29.6 0.0 0.048 14.0 0.0 2.6 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain DNA_ligase_IV PF11411.8 KXL48290.1 - 0.00022 21.3 0.0 0.00053 20.1 0.0 1.6 1 0 0 1 1 1 1 DNA ligase IV PTCB-BRCT PF12738.7 KXL48290.1 - 0.023 14.6 0.0 4.5 7.3 0.0 2.6 2 0 0 2 2 2 0 twin BRCT domain mRNA_cap_enzyme PF01331.19 KXL48290.1 - 0.068 13.0 0.0 1.2 9.0 0.0 2.6 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain Amidohydro_2 PF04909.14 KXL48291.1 - 1.1e-29 104.2 0.5 1.5e-29 103.7 0.5 1.2 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 KXL48291.1 - 0.012 15.0 0.0 1.7 8.0 0.0 2.2 2 0 0 2 2 2 0 TatD related DNase DIOX_N PF14226.6 KXL48292.1 - 7.7e-27 94.4 0.1 1.3e-26 93.7 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXL48292.1 - 7.9e-19 68.0 0.0 1.2e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily LDB19 PF13002.7 KXL48295.1 - 3.2e-41 141.2 0.1 1.2e-40 139.4 0.1 1.9 1 1 1 2 2 2 1 Arrestin_N terminal like Arrestin_N PF00339.29 KXL48295.1 - 0.00014 22.0 0.0 0.00033 20.7 0.0 1.6 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Spo0M PF07070.11 KXL48295.1 - 0.0055 16.3 0.0 0.0092 15.5 0.0 1.2 1 0 0 1 1 1 1 SpoOM protein F-box-like PF12937.7 KXL48296.1 - 2.7e-05 24.0 0.4 0.00016 21.5 0.3 2.2 2 0 0 2 2 2 1 F-box-like Amidohydro_1 PF01979.20 KXL48297.1 - 7.1e-45 153.8 0.0 8.8e-45 153.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXL48297.1 - 2.7e-12 46.9 0.3 1.5e-07 31.3 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family PP2C PF00481.21 KXL48298.1 - 2e-60 204.6 2.9 1.2e-49 169.3 0.1 3.7 2 1 2 4 4 4 3 Protein phosphatase 2C CRA PF06589.11 KXL48298.1 - 0.66 10.1 7.4 1.6 8.8 7.4 1.6 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) SAM_1 PF00536.30 KXL48300.1 - 1.9e-13 50.6 0.0 3.5e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KXL48300.1 - 2.2e-12 46.9 0.0 4.4e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 KXL48300.1 - 1.7e-11 44.6 0.0 3.1e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_PNT PF02198.16 KXL48300.1 - 8e-05 22.5 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain RasGAP_C PF03836.15 KXL48300.1 - 0.035 14.2 0.0 0.072 13.2 0.0 1.5 1 0 0 1 1 1 0 RasGAP C-terminus YabA PF06156.13 KXL48300.1 - 0.057 14.1 0.0 0.13 12.9 0.0 1.5 1 0 0 1 1 1 0 Initiation control protein YabA TMF_TATA_bd PF12325.8 KXL48300.1 - 0.068 13.4 0.5 0.13 12.5 0.5 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding ZapB PF06005.12 KXL48300.1 - 0.072 13.5 0.7 0.14 12.6 0.7 1.4 1 0 0 1 1 1 0 Cell division protein ZapB DUF4201 PF13870.6 KXL48300.1 - 0.089 12.5 0.6 0.14 11.9 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) SAM_4 PF18017.1 KXL48300.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DivIC PF04977.15 KXL48300.1 - 0.15 11.8 0.8 0.29 10.9 0.8 1.4 1 0 0 1 1 1 0 Septum formation initiator GTP_EFTU PF00009.27 KXL48301.1 - 1.7e-18 66.8 0.0 4.9e-18 65.4 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KXL48301.1 - 2.5e-08 34.2 0.8 2.4e-07 31.1 0.6 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KXL48301.1 - 3.5e-05 24.1 0.0 0.0001 22.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KXL48301.1 - 0.0048 17.0 0.2 0.02 15.0 0.1 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXL48301.1 - 0.02 14.8 0.3 5.6 6.8 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 KXL48301.1 - 0.037 13.8 0.7 5.8 6.6 0.1 3.1 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 KXL48301.1 - 0.61 10.1 2.1 0.87 9.6 0.7 2.0 2 0 0 2 2 2 0 Dynamin family Sec2p PF06428.11 KXL48303.1 - 1.8e-10 40.6 13.2 1.8e-10 40.6 13.2 2.7 2 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p ATG16 PF08614.11 KXL48303.1 - 0.00063 20.0 25.8 0.0014 18.9 2.1 2.1 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) CALCOCO1 PF07888.11 KXL48303.1 - 0.0013 17.7 28.8 0.038 12.9 2.4 2.0 2 0 0 2 2 2 2 Calcium binding and coiled-coil domain (CALCOCO1) like ADIP PF11559.8 KXL48303.1 - 0.0039 17.3 26.2 0.0044 17.1 3.8 2.5 2 1 0 2 2 2 1 Afadin- and alpha -actinin-Binding DUF4795 PF16043.5 KXL48303.1 - 0.012 15.2 0.7 0.012 15.2 0.7 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) HH_signal PF01085.18 KXL48303.1 - 0.015 15.0 0.7 0.028 14.1 0.7 1.5 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain Tropomyosin PF00261.20 KXL48303.1 - 0.017 14.5 0.7 0.017 14.5 0.7 2.8 2 1 0 2 2 2 0 Tropomyosin V_ATPase_I PF01496.19 KXL48303.1 - 0.021 12.8 11.3 0.03 12.2 11.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BST2 PF16716.5 KXL48303.1 - 0.04 14.5 2.6 0.04 14.5 2.6 4.1 2 2 2 4 4 4 0 Bone marrow stromal antigen 2 Fez1 PF06818.15 KXL48303.1 - 0.34 11.3 21.2 1.3 9.5 0.5 2.1 2 0 0 2 2 2 0 Fez1 Fib_alpha PF08702.10 KXL48303.1 - 0.58 10.3 15.0 2.8 8.1 1.9 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family GAS PF13851.6 KXL48303.1 - 1.2 8.4 29.6 0.3 10.4 4.1 3.0 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding FAM76 PF16046.5 KXL48303.1 - 1.7 7.9 18.2 0.085 12.2 1.1 2.2 1 1 1 2 2 2 0 FAM76 protein Lebercilin PF15619.6 KXL48303.1 - 1.8 8.2 29.8 0.044 13.4 2.6 3.3 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease HAUS5 PF14817.6 KXL48303.1 - 2.8 6.6 23.6 0.62 8.8 13.3 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 5 FlxA PF14282.6 KXL48303.1 - 4.7 7.3 29.1 1.1 9.3 11.6 3.4 2 2 1 3 3 3 0 FlxA-like protein APG6_N PF17675.1 KXL48303.1 - 5.1 7.6 32.9 0.56 10.7 3.1 3.1 2 1 1 3 3 3 0 Apg6 coiled-coil region Cnn_1N PF07989.11 KXL48303.1 - 6.8 6.9 24.8 1 9.6 10.8 3.3 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 UPF0227 PF05728.12 KXL48303.1 - 9.2 6.2 6.8 21 5.0 0.6 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0227) FapA PF03961.13 KXL48303.1 - 9.3 4.7 15.7 11 4.5 9.6 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A bZIP_1 PF00170.21 KXL48304.1 - 1.8e-08 34.3 13.7 1.8e-08 34.3 13.7 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KXL48304.1 - 2.1e-06 27.7 15.2 2.1e-06 27.7 15.2 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 KXL48304.1 - 0.0016 18.9 12.6 0.0016 18.9 12.6 2.0 1 1 1 2 2 2 1 bZIP Maf transcription factor DivIC PF04977.15 KXL48304.1 - 7.3 6.4 5.9 17 5.3 5.9 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF4407 PF14362.6 KXL48304.1 - 9.6 5.5 10.3 13 5.0 10.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HAGH_C PF16123.5 KXL48305.1 - 8e-18 64.7 0.1 1.2e-17 64.1 0.1 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KXL48305.1 - 3.8e-16 59.7 7.5 1.2e-14 54.8 7.5 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXL48305.1 - 0.0056 16.2 2.4 0.037 13.5 2.4 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain BcrAD_BadFG PF01869.20 KXL48305.1 - 0.094 12.2 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family DUF1236 PF06823.12 KXL48305.1 - 0.099 12.5 0.0 0.67 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1236) zf-DNL PF05180.12 KXL48306.1 - 1.5e-26 92.1 0.6 2.3e-26 91.5 0.6 1.3 1 0 0 1 1 1 1 DNL zinc finger Zn_Tnp_IS1595 PF12760.7 KXL48306.1 - 0.63 10.1 5.4 10 6.2 0.8 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Cullin PF00888.22 KXL48307.1 - 1.7e-180 601.7 0.0 2.1e-180 601.4 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KXL48307.1 - 7.9e-25 86.7 0.7 1.6e-24 85.7 0.7 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain Nse4_C PF08743.10 KXL48310.1 - 0.014 15.7 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 Nse4 C-terminal A_deaminase PF00962.22 KXL48311.1 - 9.3e-22 77.8 0.0 1.9e-21 76.8 0.0 1.5 1 1 0 1 1 1 1 Adenosine/AMP deaminase RESP18 PF14948.6 KXL48311.1 - 0.039 14.3 0.0 0.079 13.3 0.0 1.4 1 0 0 1 1 1 0 RESP18 domain ATG2_CAD PF13329.6 KXL48312.1 - 7.8e-31 106.9 0.0 1.4e-30 106.1 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 KXL48312.1 - 8.8e-24 83.7 0.0 4.5e-23 81.4 0.0 2.3 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain D5_N PF08706.11 KXL48312.1 - 0.18 12.0 0.0 0.85 9.9 0.0 2.2 2 0 0 2 2 2 0 D5 N terminal like MFS_1 PF07690.16 KXL48313.1 - 5.2e-33 114.4 88.0 3.6e-26 91.9 52.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL48313.1 - 1.3e-06 27.6 44.1 0.00032 19.7 14.4 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter adh_short_C2 PF13561.6 KXL48314.1 - 1.9e-62 210.9 0.0 2.2e-62 210.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL48314.1 - 3e-45 154.1 0.1 3.6e-45 153.8 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL48314.1 - 5.2e-12 46.1 0.2 7.7e-12 45.5 0.2 1.2 1 0 0 1 1 1 1 KR domain DEAD PF00270.29 KXL48315.1 - 3.5e-29 101.8 0.1 6e-29 101.1 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXL48315.1 - 1.4e-24 86.6 0.0 5.6e-24 84.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL48315.1 - 3.9e-06 27.0 0.0 7.5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ATP-synt_G PF04718.15 KXL48316.1 - 1.1e-32 112.8 0.1 2.5e-32 111.7 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit AAL_decarboxy PF03306.13 KXL48319.1 - 1.1e-51 175.2 1.5 1.4e-51 174.9 1.5 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase Sigma70_r1_1 PF03979.14 KXL48319.1 - 0.15 12.1 0.1 2.9 8.0 0.0 2.4 3 0 0 3 3 3 0 Sigma-70 factor, region 1.1 DUF3591 PF12157.8 KXL48320.1 - 2.1e-171 570.5 1.0 2.9e-171 570.0 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.23 KXL48320.1 - 0.0057 16.7 0.7 0.011 15.8 0.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 KXL48320.1 - 0.0088 15.9 0.7 0.022 14.6 0.7 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2 PF00096.26 KXL48321.1 - 2.6e-09 37.0 14.9 1.1e-05 25.5 1.7 3.7 4 0 0 4 4 3 2 Zinc finger, C2H2 type Fungal_trans PF04082.18 KXL48321.1 - 3.4e-09 36.1 0.8 5.6e-09 35.4 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.6 KXL48321.1 - 1.7e-07 31.5 16.2 0.00057 20.5 0.8 4.2 4 0 0 4 4 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXL48321.1 - 0.00067 19.6 0.4 0.069 13.2 0.2 2.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXL48321.1 - 0.0024 18.1 9.6 0.26 11.6 0.0 3.6 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding Zn_clus PF00172.18 KXL48321.1 - 0.0058 16.7 10.6 0.02 15.0 10.6 2.0 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 KXL48321.1 - 0.02 15.3 8.4 0.25 11.9 0.3 3.7 3 0 0 3 3 3 0 Zinc-finger double domain zf-met PF12874.7 KXL48321.1 - 0.026 14.9 4.4 1.1 9.8 0.1 3.6 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KXL48321.1 - 0.11 12.3 1.3 1.3 8.8 0.2 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KXL48321.1 - 0.19 12.1 1.6 2.4 8.5 0.2 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 KXL48321.1 - 1.2 9.2 9.9 0.87 9.6 0.2 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Melibiase PF02065.18 KXL48322.1 - 1.2e-37 129.7 0.0 1.7e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 KXL48322.1 - 5.7e-09 35.9 0.0 1.1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Glyco_hydro_31 PF01055.26 KXL48322.1 - 0.011 14.9 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 Melibiase_2 PF16499.5 KXL48322.1 - 0.025 13.7 0.0 0.046 12.9 0.0 1.4 1 0 0 1 1 1 0 Alpha galactosidase A Peptidase_C13 PF01650.18 KXL48323.1 - 2.7e-23 82.8 0.1 7.5e-23 81.4 0.1 1.7 1 1 0 1 1 1 1 Peptidase C13 family Aldolase_II PF00596.21 KXL48324.1 - 1.8e-47 161.7 0.1 2.2e-47 161.4 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain NADH_4Fe-4S PF10589.9 KXL48324.1 - 0.025 14.6 0.0 1.3 9.1 0.0 2.3 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Homeobox_KN PF05920.11 KXL48325.1 - 2.6e-14 52.9 0.9 5.5e-14 51.8 0.9 1.6 1 0 0 1 1 1 1 Homeobox KN domain HTH_Tnp_Tc5 PF03221.16 KXL48325.1 - 1.6e-05 24.9 0.4 6e-05 23.0 0.1 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Homeodomain PF00046.29 KXL48325.1 - 0.00013 21.7 0.3 0.00033 20.4 0.3 1.7 1 0 0 1 1 1 1 Homeodomain zf-C2H2_4 PF13894.6 KXL48325.1 - 0.0023 18.6 2.2 0.0023 18.6 2.2 5.9 7 0 0 7 7 7 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KXL48325.1 - 7.8 6.9 11.8 48 4.4 2.5 3.8 2 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) 5_nucleotid_C PF02872.18 KXL48326.1 - 6.9e-40 136.8 0.0 1.2e-39 136.0 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KXL48326.1 - 2.7e-05 24.8 0.0 4.5e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase His_Phos_1 PF00300.22 KXL48327.1 - 1.4e-05 24.9 1.4 4.9 6.8 0.8 4.2 3 1 0 3 3 3 3 Histidine phosphatase superfamily (branch 1) DNA_topoisoIV PF00521.20 KXL48328.1 - 1.1e-130 436.4 0.5 2.7e-130 435.1 0.1 1.8 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KXL48328.1 - 1.1e-49 168.0 0.8 3.7e-49 166.3 0.8 2.0 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KXL48328.1 - 2.4e-26 92.3 2.9 5.4e-26 91.1 2.9 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KXL48328.1 - 3.2e-12 46.9 0.0 7.7e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KXL48328.1 - 6.6e-08 32.7 0.0 8.7e-07 29.1 0.0 2.9 2 0 0 2 2 2 1 Toprim domain zf-C2H2_jaz PF12171.8 KXL48329.1 - 1.2e-09 38.2 0.5 1.9e-09 37.5 0.5 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXL48329.1 - 4.2e-07 30.1 0.5 7.3e-07 29.4 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type OrsD PF12013.8 KXL48329.1 - 0.024 15.1 0.8 2.6 8.5 0.3 2.3 1 1 1 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-DBF PF07535.12 KXL48329.1 - 0.03 14.4 0.1 0.058 13.5 0.1 1.4 1 0 0 1 1 1 0 DBF zinc finger zf-U1 PF06220.12 KXL48329.1 - 0.032 14.0 0.1 0.069 12.9 0.1 1.5 1 0 0 1 1 1 0 U1 zinc finger zf-C2H2_2 PF12756.7 KXL48329.1 - 0.098 13.0 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KXL48329.1 - 0.17 12.4 0.5 0.29 11.7 0.5 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type SANT_DAMP1_like PF16282.5 KXL48330.1 - 3.4e-18 65.6 1.6 6.8e-18 64.7 1.6 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-binding PF00249.31 KXL48330.1 - 0.00059 20.0 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXL48330.1 - 0.0089 16.3 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain KOW PF00467.29 KXL48331.1 - 2.2e-05 24.3 2.3 7.9e-05 22.5 2.3 2.0 1 0 0 1 1 1 1 KOW motif DUF4208 PF13907.6 KXL48331.1 - 0.98 9.9 7.4 0.14 12.6 2.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) PTCB-BRCT PF12738.7 KXL48332.1 - 1.1e-42 143.8 2.5 7.4e-20 70.7 0.1 3.6 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.26 KXL48332.1 - 1.4e-32 111.9 0.0 2.7e-14 53.3 0.0 4.2 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KXL48332.1 - 3.7e-12 46.5 0.0 6.3e-05 23.3 0.0 4.3 4 0 0 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KXL48332.1 - 3.7e-06 27.1 3.0 0.14 12.5 0.1 4.2 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 KXL48332.1 - 4.8e-05 23.4 0.4 0.0071 16.4 0.1 3.3 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KXL48332.1 - 0.00057 19.7 0.0 8.5 6.3 0.0 3.5 2 1 1 3 3 3 3 Regulator of Ty1 transposition protein 107 BRCT domain OxoDH_E1alpha_N PF12573.8 KXL48333.1 - 0.038 13.8 0.1 0.091 12.5 0.1 1.7 1 0 0 1 1 1 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal Arrestin_C PF02752.22 KXL48335.1 - 2.4e-22 79.8 0.0 1.2e-21 77.6 0.0 2.1 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KXL48335.1 - 1.3e-09 38.3 0.0 1.1e-05 25.6 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain B-block_TFIIIC PF04182.12 KXL48336.1 - 3.3e-12 46.4 0.0 1e-11 44.8 0.0 1.9 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC MFAP1 PF06991.11 KXL48337.1 - 3.2e-65 220.0 35.5 3.2e-65 220.0 35.5 2.9 2 1 1 3 3 3 1 Microfibril-associated/Pre-mRNA processing TSLP PF15216.6 KXL48339.1 - 0.003 17.9 1.6 0.0049 17.2 1.4 1.4 1 1 0 1 1 1 1 Thymic stromal lymphopoietin Pro_isomerase PF00160.21 KXL48340.1 - 1.7e-44 151.9 0.0 3.9e-44 150.7 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-NOSIP PF15906.5 KXL48340.1 - 0.00045 20.3 0.0 0.0012 18.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein U-box PF04564.15 KXL48340.1 - 0.0013 18.9 0.0 0.008 16.3 0.0 2.3 1 1 1 2 2 2 1 U-box domain DNMT1-RFD PF12047.8 KXL48341.1 - 0.012 15.7 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 Cytosine specific DNA methyltransferase replication foci domain CPSase_C PF18302.1 KXL48341.1 - 0.13 12.6 0.1 0.48 11.0 0.1 2.0 1 0 0 1 1 1 0 Carbamoyl phosphate synthetase C-terminal domain TruB_N PF01509.18 KXL48342.1 - 3.2e-45 154.1 0.0 7e-45 153.0 0.0 1.5 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KXL48342.1 - 2.4e-05 24.4 0.0 5.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain LSM PF01423.22 KXL48343.1 - 1.4e-16 59.9 0.1 1.9e-16 59.5 0.1 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KXL48343.1 - 0.14 11.8 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Hfq protein Dak1 PF02733.17 KXL48344.1 - 2e-108 362.0 4.1 3.3e-108 361.3 4.1 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KXL48344.1 - 5.8e-45 153.3 2.4 1.3e-44 152.1 2.4 1.6 1 0 0 1 1 1 1 DAK2 domain F-box-like_2 PF13013.6 KXL48345.1 - 1.4e-05 25.0 0.4 0.16 11.9 0.1 2.5 2 0 0 2 2 2 2 F-box-like domain RRM_1 PF00076.22 KXL48347.1 - 1.2e-60 201.3 0.0 2.6e-20 72.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXL48347.1 - 3.5e-10 39.6 0.0 2.5e-05 23.9 0.0 3.0 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXL48347.1 - 3.1e-09 36.5 0.0 0.0016 18.3 0.0 3.6 3 1 0 3 3 3 2 Occluded RNA-recognition motif RRM_8 PF11835.8 KXL48347.1 - 7.4e-06 26.1 0.0 0.013 15.7 0.0 2.5 2 0 0 2 2 2 2 RRM-like domain Nup35_RRM_2 PF14605.6 KXL48347.1 - 0.00056 19.9 0.3 8.9 6.4 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KXL48347.1 - 0.00082 19.5 0.2 5.7 7.1 0.0 3.6 3 1 0 3 3 3 2 RNA recognition motif Cas_Cas2CT1978 PF09707.10 KXL48347.1 - 0.025 14.6 0.0 4 7.6 0.0 2.8 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_Cas2CT1978) SH3_16 PF18348.1 KXL48347.1 - 0.061 13.1 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain DUF1987 PF09345.10 KXL48347.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1987) Limkain-b1 PF11608.8 KXL48347.1 - 0.13 12.4 0.3 15 5.8 0.0 3.4 4 1 0 4 4 4 0 Limkain b1 RRM_3 PF08777.11 KXL48347.1 - 0.17 11.9 0.0 2 8.5 0.0 2.5 3 0 0 3 3 3 0 RNA binding motif Borrelia_P83 PF05262.11 KXL48348.1 - 2.1 6.7 9.5 2.4 6.5 9.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein RR_TM4-6 PF06459.12 KXL48348.1 - 5.9 6.6 8.7 7 6.4 8.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FMO-like PF00743.19 KXL48350.1 - 3.5e-18 65.3 0.0 1e-17 63.8 0.0 1.7 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXL48350.1 - 2.8e-13 49.8 0.1 1.1e-11 44.5 0.3 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXL48350.1 - 4.3e-12 45.8 0.1 6.2e-10 38.7 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KXL48350.1 - 8.8e-11 41.6 0.0 2.5e-10 40.1 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXL48350.1 - 4.5e-07 30.0 2.0 1.1e-06 28.7 0.3 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXL48350.1 - 1.5e-05 25.4 1.8 0.12 12.9 1.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXL48350.1 - 0.0002 20.6 0.3 0.00072 18.8 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 KXL48350.1 - 0.00024 20.5 1.8 0.033 13.5 0.7 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 KXL48350.1 - 0.0015 18.6 0.2 1.7 8.7 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 KXL48350.1 - 0.0036 16.9 4.1 0.0036 16.9 4.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KXL48350.1 - 0.0099 15.8 0.6 0.018 14.9 0.6 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KXL48350.1 - 0.021 14.8 2.2 0.066 13.2 0.2 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KXL48350.1 - 0.022 13.5 2.3 0.13 11.0 0.6 2.5 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 KXL48350.1 - 0.079 12.3 0.4 0.2 11.0 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KXL48350.1 - 0.13 12.7 0.0 1.2 9.6 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding Amino_oxidase PF01593.24 KXL48350.1 - 0.2 10.9 0.1 0.92 8.7 0.1 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Thi4 PF01946.17 KXL48350.1 - 0.4 9.9 2.0 1.8 7.7 0.5 2.1 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 KXL48350.1 - 0.74 8.8 4.9 0.33 10.0 1.2 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A SnoaL_2 PF12680.7 KXL48351.1 - 0.004 17.8 0.1 0.0069 17.0 0.1 1.5 1 1 0 1 1 1 1 SnoaL-like domain FMO-like PF00743.19 KXL48351.1 - 0.073 11.5 0.0 0.089 11.2 0.0 1.0 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like POT1PC PF16686.5 KXL48352.1 - 3.3e-38 131.0 0.5 7.2e-37 126.6 0.0 2.9 3 0 0 3 3 3 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 KXL48352.1 - 1.3e-16 60.7 0.1 9.9e-16 57.9 0.0 2.5 3 0 0 3 3 3 1 Telomeric single stranded DNA binding POT1/CDC13 Fungus-induced PF10917.8 KXL48352.1 - 0.0017 18.6 1.0 0.0039 17.5 1.0 1.6 1 0 0 1 1 1 1 Fungus-induced protein REPA_OB_2 PF16900.5 KXL48352.1 - 0.024 14.5 0.0 0.076 12.9 0.0 1.9 1 0 0 1 1 1 0 Replication protein A OB domain DUF1168 PF06658.12 KXL48352.1 - 0.03 14.1 6.7 0.068 13.0 6.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) HAND PF09110.11 KXL48352.1 - 0.47 11.2 7.4 1.1 10.1 7.4 1.5 1 0 0 1 1 1 0 HAND Arm PF00514.23 KXL48353.1 - 1.5e-97 317.0 12.3 4.1e-14 52.0 0.0 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KXL48353.1 - 3.5e-28 97.9 0.5 9.1e-28 96.5 0.5 1.8 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.6 KXL48353.1 - 9.1e-24 83.5 7.5 1.5e-09 38.2 0.1 6.4 5 1 1 6 6 6 4 HEAT-like repeat Arm_3 PF16186.5 KXL48353.1 - 1.2e-23 82.4 2.1 2.9e-23 81.2 2.1 1.7 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_2 PF13646.6 KXL48353.1 - 2.4e-22 79.1 0.1 5.7e-10 39.5 0.0 5.3 1 1 3 4 4 4 3 HEAT repeats HEAT PF02985.22 KXL48353.1 - 1.5e-20 71.5 1.5 3.5e-06 26.8 0.0 7.5 8 0 0 8 8 8 4 HEAT repeat Arm_2 PF04826.13 KXL48353.1 - 1.8e-09 37.4 0.0 0.0027 17.2 0.0 4.0 2 1 2 4 4 4 2 Armadillo-like Adaptin_N PF01602.20 KXL48353.1 - 1.3e-06 27.3 0.0 0.00038 19.2 0.0 2.2 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_C PF11698.8 KXL48353.1 - 4.2e-05 23.6 0.0 1.4 9.0 0.0 4.4 3 2 1 4 4 4 2 V-ATPase subunit H HEAT_PBS PF03130.16 KXL48353.1 - 0.00024 21.5 4.8 0.06 14.0 0.1 4.9 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat RICTOR_V PF14668.6 KXL48353.1 - 0.0014 18.9 2.9 1.1 9.6 0.0 5.0 3 2 3 6 6 6 2 Rapamycin-insensitive companion of mTOR, domain 5 NopRA1 PF16201.5 KXL48353.1 - 0.0025 17.4 0.0 0.76 9.3 0.0 3.6 1 1 2 4 4 4 1 Nucleolar pre-ribosomal-associated protein 1 Cnd1 PF12717.7 KXL48353.1 - 0.0028 17.7 0.0 4.8 7.2 0.0 3.2 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Glycos_trans_3N PF02885.17 KXL48353.1 - 0.11 12.4 0.1 36 4.3 0.0 3.8 5 0 0 5 5 5 0 Glycosyl transferase family, helical bundle domain Mo25 PF08569.11 KXL48353.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Mo25-like NUSAP PF16006.5 KXL48353.1 - 2.2 8.0 6.0 3 7.5 6.0 1.2 1 0 0 1 1 1 0 Nucleolar and spindle-associated protein YjeF_N PF03853.15 KXL48354.1 - 1.9e-23 83.2 0.1 3.4e-23 82.4 0.1 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 KXL48354.1 - 1.7e-08 35.3 0.8 1.7e-08 35.3 0.8 2.0 2 0 0 2 2 2 1 FDF domain Sugar_tr PF00083.24 KXL48355.1 - 8.3e-84 282.0 26.2 9.5e-84 281.8 26.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL48355.1 - 7.3e-31 107.4 60.0 6.8e-24 84.5 28.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3021 PF11457.8 KXL48355.1 - 0.0095 16.3 15.8 0.0095 16.3 15.8 2.9 3 1 0 3 3 3 1 Protein of unknown function (DUF3021) adh_short PF00106.25 KXL48356.1 - 5.4e-29 101.0 0.0 7.6e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL48356.1 - 7.5e-28 97.7 0.0 9.6e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL48356.1 - 0.00071 19.5 0.0 0.0026 17.7 0.0 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXL48356.1 - 0.0011 18.5 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Nha1_C PF08619.10 KXL48357.1 - 5.8e-102 342.3 41.4 6.8e-102 342.1 41.4 1.0 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 KXL48357.1 - 3.1e-82 276.4 21.8 3.7e-82 276.1 21.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF4190 PF13828.6 KXL48357.1 - 0.074 12.8 0.1 0.074 12.8 0.1 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4190) DUF21 PF01595.20 KXL48357.1 - 4.5 7.0 8.9 0.48 10.1 2.2 2.4 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain YrhC PF14143.6 KXL48357.1 - 5 7.3 4.8 1.7 8.8 1.2 2.0 2 0 0 2 2 2 0 YrhC-like protein CTU2 PF10288.9 KXL48358.1 - 1.5e-11 44.5 3.4 2.1e-11 44.1 0.1 2.8 2 1 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 ATP_bind_3 PF01171.20 KXL48358.1 - 0.085 12.6 0.0 0.91 9.3 0.0 2.1 2 0 0 2 2 2 0 PP-loop family DZR PF12773.7 KXL48358.1 - 0.37 10.8 7.2 2.7 8.1 1.0 2.3 2 0 0 2 2 2 0 Double zinc ribbon Bystin PF05291.11 KXL48360.1 - 4.2e-131 436.6 0.0 5.3e-131 436.2 0.0 1.1 1 0 0 1 1 1 1 Bystin zf-C2H2 PF00096.26 KXL48362.1 - 3.4e-10 39.8 11.6 1.4e-05 25.2 4.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXL48362.1 - 7.6e-10 38.8 12.4 4e-05 23.8 0.3 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXL48362.1 - 2.9e-07 30.7 10.2 0.00061 20.4 2.9 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KXL48362.1 - 6e-06 26.5 1.2 1.9e-05 24.9 1.2 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KXL48362.1 - 8.2e-05 22.5 7.6 0.00014 21.8 2.1 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXL48362.1 - 0.00086 19.5 5.0 0.001 19.3 2.5 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KXL48362.1 - 0.022 15.1 0.1 0.057 13.8 0.1 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 KXL48362.1 - 0.14 12.0 4.1 3.6 7.6 0.3 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 KXL48362.1 - 0.29 11.0 8.9 1.3 8.9 0.9 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-BED PF02892.15 KXL48362.1 - 2.3 8.3 5.3 0.92 9.6 0.9 2.2 2 0 0 2 2 2 0 BED zinc finger Sugar_tr PF00083.24 KXL48364.1 - 3.7e-107 359.0 22.8 4.2e-107 358.8 22.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL48364.1 - 1e-24 87.1 29.3 5.5e-23 81.5 18.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily YbhQ PF11076.8 KXL48364.1 - 0.12 12.4 0.2 0.12 12.4 0.2 2.0 2 0 0 2 2 2 0 Putative inner membrane protein YbhQ Phage_holin_3_2 PF04550.12 KXL48364.1 - 2.3 8.8 7.4 0.86 10.2 3.5 2.3 2 0 0 2 2 2 0 Phage holin family 2 OATP PF03137.20 KXL48364.1 - 9.1 4.4 13.3 0.29 9.4 3.6 2.7 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Zn_clus PF00172.18 KXL48366.1 - 2.1e-06 27.8 7.4 3.5e-06 27.0 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXL48366.1 - 4.2e-05 22.7 0.5 0.00018 20.6 0.1 2.2 2 1 0 2 2 2 1 Fungal specific transcription factor domain SGL PF08450.12 KXL48367.1 - 4.2e-28 98.6 0.0 7.6e-28 97.7 0.0 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KXL48367.1 - 2.7e-05 24.3 0.0 6.6e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Arylesterase Str_synth PF03088.16 KXL48367.1 - 0.013 15.7 0.0 0.052 13.7 0.0 2.1 2 1 0 2 2 2 0 Strictosidine synthase Cas_Cas02710 PF09670.10 KXL48368.1 - 6.8e-14 51.5 4.4 1.1e-13 50.8 4.4 1.4 1 1 0 1 1 1 1 CRISPR-associated protein (Cas_Cas02710) Cas_Csm6 PF09659.10 KXL48368.1 - 0.0012 17.7 0.1 0.15 10.8 0.0 2.5 2 2 0 2 2 2 2 CRISPR-associated protein (Cas_Csm6) RAMPs PF03787.15 KXL48370.1 - 4.2e-08 33.5 0.0 9.4e-08 32.3 0.0 1.6 1 1 0 1 1 1 1 RAMP superfamily Cas_Cas6 PF01881.16 KXL48371.1 - 3.2e-21 76.4 0.0 4.9e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 CRISPR associated protein Cas6 Csm1_B PF18211.1 KXL48371.1 - 0.0002 21.2 0.0 0.00044 20.0 0.0 1.6 1 0 0 1 1 1 1 Csm1 subunit domain B DUF5545 PF17699.1 KXL48371.1 - 0.0076 16.1 1.7 0.23 11.3 0.2 2.4 2 0 0 2 2 2 2 Family of unknown function (DUF5545) SWI2_SNF2 PF18766.1 KXL48372.1 - 3.3e-28 98.9 1.3 4.1e-27 95.3 1.3 2.7 1 1 0 1 1 1 1 SWI2/SNF2 ATPase ResIII PF04851.15 KXL48372.1 - 3.5e-18 66.2 1.0 1.5e-17 64.1 1.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HSDR_N PF04313.14 KXL48372.1 - 1.4e-14 54.5 0.2 7.2e-14 52.2 0.1 2.3 2 0 0 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) DEAD PF00270.29 KXL48372.1 - 7.3e-09 35.6 0.9 4.4e-08 33.1 0.5 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_11 PF13086.6 KXL48372.1 - 0.0033 17.2 1.6 0.9 9.3 0.7 2.7 1 1 1 2 2 2 2 AAA domain AAA_22 PF13401.6 KXL48372.1 - 0.021 15.1 0.1 0.078 13.2 0.1 2.0 1 0 0 1 1 1 0 AAA domain DUF2161 PF09929.9 KXL48372.1 - 0.038 14.1 0.1 0.12 12.5 0.1 1.9 1 0 0 1 1 1 0 Putative PD-(D/E)XK phosphodiesterase (DUF2161) UvrD-helicase PF00580.21 KXL48372.1 - 0.25 10.8 3.5 0.17 11.4 1.2 2.0 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain NucS PF01939.16 KXL48373.1 - 0.001 18.5 0.0 0.013 14.9 0.0 2.0 1 1 1 2 2 2 2 Endonuclease NucS N6_Mtase PF02384.16 KXL48374.1 - 6.3e-61 206.3 0.0 1e-60 205.7 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase HsdM_N PF12161.8 KXL48374.1 - 1.7e-23 83.8 1.1 6e-23 82.0 0.1 2.5 3 0 0 3 3 3 1 HsdM N-terminal domain Methylase_S PF01420.19 KXL48374.1 - 5.3e-20 72.3 0.0 4.9e-12 46.4 0.0 2.8 3 0 0 3 3 3 2 Type I restriction modification DNA specificity domain DUF2791 PF10923.8 KXL48374.1 - 0.012 14.5 0.1 0.023 13.6 0.1 1.4 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) MTS PF05175.14 KXL48374.1 - 0.03 13.9 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain AAA_21 PF13304.6 KXL48375.1 - 5.9e-10 39.4 0.2 9e-10 38.8 0.2 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KXL48375.1 - 2.8e-08 33.9 0.0 4.6e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain DUF4276 PF14103.6 KXL48375.1 - 1.1e-05 25.7 0.0 1.9e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4276) ABM PF03992.16 KXL48376.1 - 3e-05 24.0 0.0 4.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF4188 PF13826.6 KXL48376.1 - 0.02 15.3 0.1 0.043 14.1 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.6 KXL48376.1 - 0.026 14.0 0.1 0.027 13.9 0.1 1.1 1 0 0 1 1 1 0 Haem-containing dehydratase Polysacc_deac_1 PF01522.21 KXL48378.1 - 8.4e-11 41.8 0.0 1.3e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Amidase PF01425.21 KXL48379.1 - 7.6e-102 341.6 0.0 8.7e-102 341.4 0.0 1.0 1 0 0 1 1 1 1 Amidase NAD_synthase PF02540.17 KXL48379.1 - 0.16 11.0 0.4 0.3 10.2 0.4 1.3 1 0 0 1 1 1 0 NAD synthase Ank_3 PF13606.6 KXL48380.1 - 1.8e-11 43.2 0.0 0.00085 19.6 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KXL48380.1 - 1.3e-10 41.3 0.1 0.0019 18.5 0.0 4.2 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXL48380.1 - 2.2e-10 40.9 0.0 5.1e-07 30.1 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXL48380.1 - 6.3e-10 39.5 0.0 1.7e-08 34.9 0.0 2.8 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXL48380.1 - 7.6e-09 35.6 0.0 0.063 13.8 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat DUF4646 PF15496.6 KXL48381.1 - 1.2e-11 45.3 0.0 2.4e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) ALGX PF16822.5 KXL48381.1 - 0.036 13.7 0.1 0.056 13.1 0.1 1.3 1 0 0 1 1 1 0 SGNH hydrolase-like domain, acetyltransferase AlgX p450 PF00067.22 KXL48383.1 - 8.4e-08 31.4 0.0 9.4e-08 31.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DPBB_1 PF03330.18 KXL48384.1 - 1.7e-10 41.1 0.2 1.2e-09 38.4 0.0 2.4 2 1 0 2 2 2 1 Lytic transglycolase Cerato-platanin PF07249.12 KXL48384.1 - 0.0015 18.6 0.1 0.0027 17.8 0.1 1.5 1 0 0 1 1 1 1 Cerato-platanin BNR PF02012.20 KXL48384.1 - 0.017 15.0 0.1 0.072 13.1 0.1 2.2 1 0 0 1 1 1 0 BNR/Asp-box repeat Pollen_allerg_1 PF01357.21 KXL48384.1 - 0.077 13.0 3.0 0.23 11.5 3.1 1.8 1 1 1 2 2 2 0 Pollen allergen SLS PF14611.6 KXL48385.1 - 3.3e-21 76.1 0.0 7.7e-21 74.9 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator GTP_EFTU PF00009.27 KXL48386.1 - 1.8e-55 187.5 0.0 2.9e-55 186.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KXL48386.1 - 6.3e-42 142.4 0.0 1.4e-41 141.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KXL48386.1 - 8.5e-13 48.5 2.4 8.5e-13 48.5 2.4 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXL48386.1 - 0.00073 19.6 0.1 0.018 15.1 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase A_deamin PF02137.18 KXL48387.1 - 9.7e-26 91.0 0.0 2e-24 86.7 0.0 2.7 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain Dynactin_p62 PF05502.13 KXL48389.1 - 3.8e-141 471.2 9.0 3.2e-140 468.1 9.0 1.9 1 1 0 1 1 1 1 Dynactin p62 family Macoilin PF09726.9 KXL48390.1 - 10 4.6 10.8 12 4.3 10.8 1.1 1 0 0 1 1 1 0 Macoilin family Carb_bind PF10645.9 KXL48391.1 - 3.6e-15 55.9 7.2 8.6e-15 54.7 7.2 1.7 1 0 0 1 1 1 1 Carbohydrate binding Rotamase_3 PF13616.6 KXL48392.1 - 1.6e-15 57.6 0.0 2.9e-15 56.8 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 KXL48392.1 - 5.5e-15 56.1 0.0 6.9e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KXL48392.1 - 1.2e-05 26.2 0.0 1.3e-05 26.1 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain 2OG-FeII_Oxy_2 PF13532.6 KXL48393.1 - 1.2e-10 41.9 0.0 3.9e-09 37.0 0.0 2.2 1 1 1 2 2 2 2 2OG-Fe(II) oxygenase superfamily SnoaL_2 PF12680.7 KXL48395.1 - 0.0069 17.0 0.1 0.0089 16.7 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF1521 PF07481.11 KXL48395.1 - 0.056 13.4 0.0 0.075 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1521) CDH-cyt PF16010.5 KXL48396.1 - 8.5e-24 84.2 4.8 1.4e-23 83.6 4.8 1.2 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 KXL48396.1 - 5.9e-06 26.5 1.0 9.7e-06 25.8 1.0 1.2 1 0 0 1 1 1 1 DOMON domain DUF1700 PF08006.11 KXL48396.1 - 2 7.9 6.7 3.5 7.1 6.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) RRM_1 PF00076.22 KXL48397.1 - 1.1e-18 66.9 0.1 3.9e-18 65.0 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXL48397.1 - 6.9e-05 22.9 0.0 0.00032 20.7 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 KXL48397.1 - 0.023 14.3 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EB1 PF03271.17 KXL48398.1 - 7.3e-17 61.3 0.5 1.6e-16 60.3 0.5 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 KXL48398.1 - 1.5e-07 31.6 0.3 2.9e-07 30.6 0.2 1.5 2 0 0 2 2 2 1 Calponin homology (CH) domain Suppressor_APC PF11414.8 KXL48398.1 - 0.1 12.7 0.3 0.19 11.8 0.3 1.5 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein CCDC106 PF15794.5 KXL48398.1 - 0.11 12.1 0.2 6 6.5 0.2 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 FoP_duplication PF13865.6 KXL48398.1 - 1.6 9.3 5.2 2.6 8.7 5.2 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 DUF2207 PF09972.9 KXL48399.1 - 0.012 14.4 6.8 0.35 9.6 0.8 2.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) DUF3487 PF11990.8 KXL48399.1 - 2.3 8.1 7.2 17 5.3 3.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) GFA PF04828.14 KXL48400.1 - 0.00017 21.8 0.7 0.00017 21.8 0.7 1.9 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Pkinase PF00069.25 KXL48401.1 - 1.7e-63 214.4 0.0 2.1e-63 214.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL48401.1 - 6.7e-34 117.3 0.0 9.7e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXL48401.1 - 4.7e-07 29.4 0.0 7.5e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXL48401.1 - 7.6e-05 21.6 0.0 0.00011 21.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXL48401.1 - 0.084 12.2 0.0 0.25 10.7 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M41 PF01434.18 KXL48403.1 - 8.1e-67 224.8 0.1 1.9e-66 223.6 0.1 1.7 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KXL48403.1 - 4.8e-43 146.7 0.0 9.9e-43 145.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXL48403.1 - 1e-09 38.0 0.0 2.8e-09 36.6 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 KXL48403.1 - 6e-08 33.0 0.1 1.6e-07 31.6 0.1 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 KXL48403.1 - 0.00015 21.7 0.0 0.00045 20.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXL48403.1 - 0.0031 17.9 0.2 0.18 12.1 0.2 2.8 1 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 KXL48403.1 - 0.0059 15.9 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KXL48403.1 - 0.0066 16.7 0.1 1.2 9.4 0.1 2.7 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KXL48403.1 - 0.015 15.0 0.0 0.045 13.5 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KXL48403.1 - 0.072 13.2 0.0 0.21 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) NYD-SP28 PF14772.6 KXL48403.1 - 0.075 13.1 2.3 2.1 8.4 0.0 2.6 2 0 0 2 2 2 0 Sperm tail Forkhead PF00250.18 KXL48405.1 - 6.8e-34 116.0 0.1 1.2e-33 115.2 0.1 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KXL48405.1 - 4.8e-09 36.4 0.1 1.2e-08 35.1 0.1 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KXL48405.1 - 0.0084 16.4 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain CBP_BcsO PF17037.5 KXL48405.1 - 0.091 12.9 0.2 0.091 12.9 0.2 3.0 3 1 1 4 4 4 0 Cellulose biosynthesis protein BcsO Topoisom_bac PF01131.20 KXL48406.1 - 4.4e-105 352.1 0.0 1.4e-97 327.3 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.22 KXL48406.1 - 2.5e-20 72.6 0.0 6.9e-20 71.2 0.0 1.8 1 0 0 1 1 1 1 Toprim domain DnaJ PF00226.31 KXL48407.1 - 2.3e-05 24.4 0.0 4e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 KXL48407.1 - 0.00076 19.5 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 Pam16 IU_nuc_hydro PF01156.19 KXL48408.1 - 8.5e-80 268.6 0.0 1e-79 268.3 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF3445 PF11927.8 KXL48408.1 - 0.047 13.3 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3445) GST_N_3 PF13417.6 KXL48409.1 - 6.7e-13 48.9 0.0 1.4e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXL48409.1 - 7.8e-13 48.5 0.0 2e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXL48409.1 - 1.1e-12 48.1 0.0 3e-12 46.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXL48409.1 - 1e-10 41.7 0.0 2.1e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXL48409.1 - 1.8e-10 41.0 0.0 3.3e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXL48409.1 - 1.9e-05 24.6 0.0 3.6e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Podoplanin PF05808.11 KXL48410.1 - 0.0023 18.0 1.4 0.0041 17.2 1.4 1.3 1 0 0 1 1 1 1 Podoplanin VSP PF03302.13 KXL48410.1 - 0.0075 15.2 0.6 0.011 14.7 0.6 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Syndecan PF01034.20 KXL48410.1 - 0.017 15.0 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain DUF4690 PF15756.5 KXL48410.1 - 0.027 15.1 0.6 0.1 13.2 0.7 1.9 2 0 0 2 2 2 0 Small Novel Rich in Cartilage CYYR1 PF10873.8 KXL48410.1 - 0.031 14.7 0.3 0.084 13.3 0.0 1.8 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 EphA2_TM PF14575.6 KXL48410.1 - 0.035 15.0 0.0 0.067 14.1 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 KXL48410.1 - 0.069 12.9 2.9 0.15 11.8 2.9 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 WSS_VP PF12175.8 KXL48410.1 - 0.25 10.8 2.0 4.2 6.8 0.0 2.3 2 0 0 2 2 2 0 White spot syndrome virus structural envelope protein VP SKG6 PF08693.10 KXL48410.1 - 1.5 8.3 7.5 2.6 7.5 7.5 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain KH_1 PF00013.29 KXL48411.1 - 1.3e-41 140.2 7.1 2.5e-17 62.5 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KXL48411.1 - 3.9e-12 45.8 9.7 0.00019 21.2 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KXL48411.1 - 1.8e-08 34.1 5.2 0.03 14.2 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KXL48411.1 - 6.3e-05 23.0 5.7 0.12 12.5 0.2 3.4 3 0 0 3 3 3 2 NusA-like KH domain Peptidase_M20 PF01546.28 KXL48412.1 - 2.2e-06 27.5 0.0 2.5e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXL48412.1 - 0.00097 19.0 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain MFS_1 PF07690.16 KXL48413.1 - 1e-33 116.7 25.5 1e-33 116.7 25.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL48413.1 - 2.8e-12 46.2 12.3 2.8e-12 46.2 12.3 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXL48413.1 - 1.8e-07 30.0 5.7 1.8e-07 30.0 5.7 1.7 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) TRIC PF05197.13 KXL48414.1 - 0.062 12.9 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 TRIC channel Cellulase PF00150.18 KXL48416.1 - 4.2e-12 46.1 0.0 6.3e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) LRR_6 PF13516.6 KXL48417.1 - 2.1e-17 61.6 24.1 0.0041 17.1 0.1 11.9 12 0 0 12 12 12 7 Leucine Rich repeat LRR_4 PF12799.7 KXL48417.1 - 8.4e-14 51.5 15.4 0.024 15.1 0.1 7.6 3 2 6 9 9 9 7 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KXL48417.1 - 7.8e-10 38.5 0.1 2.1e-09 37.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXL48417.1 - 0.0016 18.3 0.3 0.0091 15.9 0.1 2.4 2 0 0 2 2 2 1 F-box domain DUF1699 PF08004.11 KXL48417.1 - 0.0062 16.2 0.6 2.3 7.9 0.0 4.1 3 1 1 4 4 4 1 Protein of unknown function (DUF1699) LRR_9 PF14580.6 KXL48417.1 - 0.27 10.7 1.5 1.8 8.0 0.0 2.7 2 1 0 3 3 3 0 Leucine-rich repeat LRR_1 PF00560.33 KXL48417.1 - 1.8 9.4 15.0 72 4.5 0.0 7.8 8 1 0 8 8 8 0 Leucine Rich Repeat HLH PF00010.26 KXL48419.1 - 7.1e-11 41.9 0.2 2.3e-10 40.3 0.0 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF3818 PF12825.7 KXL48420.1 - 1.1e-52 179.2 0.8 4e-31 108.3 0.2 3.0 2 1 1 3 3 3 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KXL48420.1 - 1.3e-36 125.5 0.0 4.3e-36 123.8 0.0 1.9 2 0 0 2 2 2 1 PX-associated DUF615 PF04751.14 KXL48420.1 - 0.0045 17.0 1.4 4.6 7.2 0.1 3.6 3 1 0 3 3 3 2 Protein of unknown function (DUF615) Fungal_trans PF04082.18 KXL48423.1 - 1.3e-28 99.8 0.0 2.1e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL48423.1 - 3e-09 36.8 10.9 4.6e-09 36.2 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIS_C PF01096.18 KXL48426.1 - 4e-19 68.2 4.3 4.7e-19 68.0 4.3 1.1 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Baculo_LEF5_C PF11792.8 KXL48426.1 - 0.017 14.8 0.2 0.021 14.5 0.2 1.2 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain HeLo PF14479.6 KXL48427.1 - 8.4e-34 117.2 3.2 1.1e-33 116.8 3.2 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation YceD PF02620.17 KXL48427.1 - 0.044 13.9 0.6 0.088 12.9 0.6 1.4 1 0 0 1 1 1 0 Large ribosomal RNA subunit accumulation protein YceD Hc1 PF07432.13 KXL48427.1 - 0.062 13.7 5.2 0.11 12.9 5.2 1.5 1 0 0 1 1 1 0 Histone H1-like protein Hc1 Syntaxin-6_N PF09177.11 KXL48427.1 - 2.1 9.0 8.8 7.6 7.2 0.2 2.7 1 1 2 3 3 3 0 Syntaxin 6, N-terminal WD40 PF00400.32 KXL48428.1 - 6.7e-135 435.0 8.7 9.3e-10 39.0 0.0 12.8 12 0 0 12 12 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL48428.1 - 4.8e-56 187.0 5.8 3.6e-05 24.0 0.0 12.2 1 1 11 12 12 12 12 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXL48428.1 - 1.2e-42 146.1 7.6 0.0035 16.3 0.0 11.6 1 1 10 11 11 11 11 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KXL48428.1 - 1.3e-26 91.9 0.7 0.85 9.6 0.0 11.0 12 0 0 12 12 11 8 WD40-like Beta Propeller Repeat NACHT PF05729.12 KXL48428.1 - 1.1e-12 48.2 0.1 4.6e-12 46.2 0.0 2.2 2 0 0 2 2 2 1 NACHT domain eIF2A PF08662.11 KXL48428.1 - 1.2e-09 38.4 0.0 0.046 13.6 0.0 4.7 1 1 5 6 6 6 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KXL48428.1 - 4e-09 35.7 5.2 7 5.2 0.0 8.9 1 1 9 11 11 11 1 Nucleoporin Nup120/160 Proteasome_A_N PF10584.9 KXL48428.1 - 4.7e-07 29.4 3.2 45 3.8 0.0 8.9 9 0 0 9 9 9 0 Proteasome subunit A N-terminal signature AAA_16 PF13191.6 KXL48428.1 - 4.8e-07 30.3 0.1 2.3e-06 28.1 0.1 2.2 1 0 0 1 1 1 1 AAA ATPase domain DPPIV_N PF00930.21 KXL48428.1 - 0.0012 17.7 0.9 18 4.0 0.0 6.5 4 3 1 6 6 6 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nbas_N PF15492.6 KXL48428.1 - 0.0013 18.1 7.7 13 5.0 0.1 7.1 2 2 7 9 9 9 0 Neuroblastoma-amplified sequence, N terminal APS_kinase PF01583.20 KXL48428.1 - 0.002 18.0 0.1 0.0043 17.0 0.1 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase GluRS_N PF18466.1 KXL48428.1 - 0.0078 16.6 13.3 1e+02 3.4 0.0 9.4 11 0 0 11 11 10 0 Glutamate--tRNA ligase N-terminal domain AAA_22 PF13401.6 KXL48428.1 - 0.023 15.0 0.0 0.11 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KXL48428.1 - 0.041 13.1 0.0 0.093 11.9 0.0 1.6 1 1 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 KXL48428.1 - 0.073 13.6 0.2 0.42 11.2 0.2 2.4 1 1 0 1 1 1 0 AAA domain SMP_2 PF10144.9 KXL48428.1 - 0.077 12.6 0.0 27 4.4 0.0 3.9 2 1 1 3 3 3 0 Bacterial virulence factor haemolysin AAA_30 PF13604.6 KXL48428.1 - 0.085 12.6 0.0 0.085 12.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 KXL48428.1 - 0.22 11.7 1.5 2.9 8.0 0.1 3.5 4 0 0 4 4 4 0 AAA domain KAP_NTPase PF07693.14 KXL48428.1 - 0.35 10.1 1.4 0.73 9.0 1.2 1.6 1 1 0 1 1 1 0 KAP family P-loop domain DUF4596 PF15363.6 KXL48428.1 - 3.6 7.9 9.6 32 4.8 0.6 5.4 8 0 0 8 8 5 0 Domain of unknown function (DUF4596) SurE PF01975.17 KXL48428.1 - 8.8 6.0 7.8 64 3.2 0.1 4.8 3 3 2 5 5 5 0 Survival protein SurE Glyco_hydro81C PF17652.1 KXL48430.1 - 4.8e-160 532.5 5.9 8.2e-160 531.8 5.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KXL48430.1 - 3.6e-111 371.4 5.8 3.6e-111 371.4 5.8 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 81 N-terminal domain Cyclase PF04199.13 KXL48431.1 - 2.4e-16 60.2 0.1 3.3e-16 59.8 0.1 1.2 1 0 0 1 1 1 1 Putative cyclase DUF2015 PF09435.10 KXL48432.1 - 7e-42 141.8 0.0 9e-42 141.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) RRM_1 PF00076.22 KXL48433.1 - 2.1e-33 114.0 0.0 5.9e-16 58.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXL48433.1 - 0.00045 19.8 0.0 0.017 14.7 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXL48433.1 - 0.00045 20.3 0.0 0.031 14.4 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif OB_RNB PF08206.11 KXL48433.1 - 0.043 13.5 0.4 4.2 7.1 0.1 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain Limkain-b1 PF11608.8 KXL48433.1 - 0.082 13.0 0.1 0.74 9.9 0.0 2.3 2 0 0 2 2 2 0 Limkain b1 PHM7_cyt PF14703.6 KXL48433.1 - 0.12 12.6 0.0 0.61 10.3 0.0 1.9 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Tom7 PF08038.12 KXL48434.1 - 6.6e-14 51.3 0.1 1e-13 50.7 0.1 1.3 1 0 0 1 1 1 1 TOM7 family Ribosomal_L28e PF01778.17 KXL48435.1 - 4.8e-34 117.6 2.8 5.9e-34 117.3 2.8 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family DUF2156 PF09924.9 KXL48435.1 - 0.08 11.9 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2156) Sec15 PF04091.12 KXL48436.1 - 4.1e-95 318.8 0.7 8.3e-95 317.8 0.7 1.6 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like Sec8_exocyst PF04048.14 KXL48436.1 - 2e-05 24.5 3.2 2e-05 24.5 3.2 3.3 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain COG2 PF06148.11 KXL48436.1 - 0.00025 21.1 3.3 0.00025 21.1 3.3 3.0 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 ATG16 PF08614.11 KXL48436.1 - 0.0012 19.1 2.9 0.0035 17.6 2.9 1.8 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) COG5 PF10392.9 KXL48436.1 - 0.0016 18.6 3.8 0.0016 18.6 3.8 2.8 2 2 1 3 3 3 1 Golgi transport complex subunit 5 TMCCDC2 PF15844.5 KXL48436.1 - 0.044 13.7 0.0 0.42 10.5 0.1 2.4 2 0 0 2 2 2 0 Transmembrane and coiled-coil domain-containing protein 2 Vps51 PF08700.11 KXL48436.1 - 0.077 13.1 0.1 0.65 10.1 0.1 2.8 1 0 0 1 1 1 0 Vps51/Vps67 DUF4201 PF13870.6 KXL48436.1 - 0.097 12.4 2.6 0.23 11.2 2.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Mre11_DNA_bind PF04152.14 KXL48436.1 - 0.12 12.6 1.5 1.4 9.2 0.0 3.0 3 0 0 3 3 3 0 Mre11 DNA-binding presumed domain Fib_alpha PF08702.10 KXL48436.1 - 0.14 12.3 5.4 2.2 8.4 1.6 3.2 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Vps54_N PF10475.9 KXL48436.1 - 0.24 10.6 10.9 0.017 14.4 4.6 2.3 3 0 0 3 3 3 0 Vacuolar-sorting protein 54, of GARP complex RRM_2 PF04059.12 KXL48438.1 - 1.5e-25 89.2 0.1 2e-25 88.8 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 KXL48438.1 - 0.00049 19.9 0.0 0.00073 19.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.15 KXL48438.1 - 0.15 12.1 0.1 0.21 11.6 0.1 1.2 1 0 0 1 1 1 0 Smg-4/UPF3 family Phosphodiest PF01663.22 KXL48439.1 - 7.9e-17 61.9 1.4 3.3e-11 43.4 0.1 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KXL48439.1 - 1.3e-07 31.4 0.0 3.5e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 KXL48439.1 - 0.0042 16.5 0.1 0.0072 15.7 0.1 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF229 PF02995.17 KXL48439.1 - 0.014 14.0 0.1 0.021 13.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Importin_rep_3 PF18806.1 KXL48441.1 - 0.0036 17.3 0.0 0.075 13.1 0.0 3.1 4 0 0 4 4 4 1 Importin 13 repeat IBN_N PF03810.19 KXL48441.1 - 0.011 15.7 0.0 0.034 14.1 0.0 2.0 1 0 0 1 1 1 0 Importin-beta N-terminal domain Importin_rep PF18773.1 KXL48441.1 - 0.024 14.4 0.0 0.096 12.4 0.0 2.0 2 0 0 2 2 2 0 Importin 13 repeat ATG101 PF07855.12 KXL48442.1 - 9.2e-51 171.9 0.1 1.1e-50 171.7 0.1 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 Mito_carr PF00153.27 KXL48444.1 - 3.3e-63 209.6 2.8 2.8e-21 75.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXL48444.1 - 0.0099 15.1 3.4 0.027 13.6 0.1 3.1 4 1 0 4 4 4 1 Gammaproteobacterial serine protease TauD PF02668.16 KXL48445.1 - 2.4e-44 152.2 0.6 6.6e-44 150.7 0.6 1.7 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KXL48445.1 - 0.012 16.3 0.0 0.036 14.7 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF971) Pkinase PF00069.25 KXL48447.1 - 4.2e-46 157.5 0.0 1.1e-45 156.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL48447.1 - 1.8e-18 66.8 0.0 4e-18 65.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KXL48447.1 - 0.00086 19.0 0.1 0.003 17.2 0.0 1.8 1 1 1 2 2 2 1 RIO1 family APH PF01636.23 KXL48447.1 - 0.0011 19.0 0.1 0.16 11.9 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KXL48447.1 - 0.0041 16.5 0.2 0.007 15.7 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXL48447.1 - 0.051 12.9 0.0 0.29 10.4 0.0 1.9 1 1 0 1 1 1 0 Kinase-like SUI1 PF01253.22 KXL48448.1 - 3.5e-25 88.3 0.1 6.7e-25 87.4 0.1 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 SHD1 PF03983.12 KXL48449.1 - 1.2e-34 117.9 0.0 2.1e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.28 KXL48449.1 - 3.3e-32 109.8 9.4 4.9e-10 38.9 0.9 4.3 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 KXL48449.1 - 9.6e-32 108.6 9.0 4.3e-10 39.3 0.5 3.9 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 KXL48449.1 - 4.7e-20 71.0 0.5 6.2e-07 29.0 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain SH3_10 PF17902.1 KXL48449.1 - 3.2e-05 23.9 0.2 0.86 9.7 0.0 3.6 3 0 0 3 3 3 2 SH3 domain SAM_4 PF18017.1 KXL48449.1 - 0.002 18.0 0.0 0.0047 16.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_3 PF08239.11 KXL48449.1 - 0.24 11.7 4.1 1.2 9.5 0.5 2.6 3 0 0 3 3 3 0 Bacterial SH3 domain ABC_tran PF00005.27 KXL48451.1 - 4.5e-49 166.5 0.1 1.3e-27 97.0 0.0 3.6 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KXL48451.1 - 2.1e-16 60.6 5.3 7.8e-06 25.9 0.0 5.0 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXL48451.1 - 4.3e-14 52.5 0.0 0.00022 20.7 0.0 3.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Chromo PF00385.24 KXL48451.1 - 5.4e-08 32.6 0.1 1e-07 31.7 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 KXL48451.1 - 6.8e-07 30.0 0.0 0.084 13.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 KXL48451.1 - 8.2e-07 28.7 0.3 0.016 15.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KXL48451.1 - 1.5e-06 28.3 0.0 0.024 14.7 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXL48451.1 - 4.2e-06 26.8 0.0 0.031 14.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KXL48451.1 - 4.4e-05 23.8 0.0 0.055 13.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KXL48451.1 - 6.7e-05 22.9 0.0 0.25 11.2 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.6 KXL48451.1 - 7.4e-05 23.0 0.0 0.072 13.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KXL48451.1 - 0.00016 21.8 3.9 0.006 16.7 0.1 3.2 4 0 0 4 4 2 1 Helicase HerA, central domain AAA_15 PF13175.6 KXL48451.1 - 0.00049 19.9 0.3 0.53 9.9 0.1 2.6 3 0 0 3 3 2 2 AAA ATPase domain RNA_helicase PF00910.22 KXL48451.1 - 0.0011 19.3 0.1 2.2 8.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 KXL48451.1 - 0.0012 19.1 0.0 1.7 8.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KXL48451.1 - 0.0016 19.0 0.1 0.72 10.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KXL48451.1 - 0.0021 17.2 0.1 0.13 11.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) SbcCD_C PF13558.6 KXL48451.1 - 0.0026 17.9 0.0 0.78 10.0 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MeaB PF03308.16 KXL48451.1 - 0.0034 16.4 0.3 1 8.3 0.0 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_14 PF13173.6 KXL48451.1 - 0.0084 16.1 0.0 6.1 6.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 KXL48451.1 - 0.0092 14.7 0.0 2.6 6.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Adaptin_N PF01602.20 KXL48451.1 - 0.01 14.4 0.2 0.032 12.8 0.2 1.7 2 0 0 2 2 2 0 Adaptin N terminal region AAA_16 PF13191.6 KXL48451.1 - 0.011 16.1 0.0 1.4 9.3 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain HEAT_EZ PF13513.6 KXL48451.1 - 0.012 16.1 2.6 0.65 10.6 0.0 4.1 3 1 1 4 4 4 0 HEAT-like repeat PduV-EutP PF10662.9 KXL48451.1 - 0.012 15.4 0.0 0.75 9.5 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 KXL48451.1 - 0.012 15.8 0.0 3.1 8.0 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 KXL48451.1 - 0.013 16.0 0.0 7.7 6.9 0.0 3.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KXL48451.1 - 0.015 15.0 0.1 7.9 6.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain Arf PF00025.21 KXL48451.1 - 0.024 14.1 0.5 10 5.5 0.0 3.1 3 0 0 3 3 3 0 ADP-ribosylation factor family FtsK_SpoIIIE PF01580.18 KXL48451.1 - 0.025 14.0 0.2 0.44 9.8 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family HEAT_2 PF13646.6 KXL48451.1 - 0.029 14.7 2.2 0.41 11.1 0.2 3.2 2 1 0 2 2 2 0 HEAT repeats TsaE PF02367.17 KXL48451.1 - 0.036 14.1 0.0 16 5.5 0.0 2.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MukB PF04310.12 KXL48451.1 - 0.04 13.7 0.1 5.2 6.8 0.0 2.3 2 0 0 2 2 2 0 MukB N-terminal Septin PF00735.18 KXL48451.1 - 0.041 13.2 0.0 3.2 7.0 0.0 2.3 2 0 0 2 2 2 0 Septin DUF3584 PF12128.8 KXL48451.1 - 0.041 11.4 1.2 2.9 5.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) NB-ARC PF00931.22 KXL48451.1 - 0.05 12.8 0.0 3.1 6.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 KXL48451.1 - 0.05 13.3 0.1 4.2 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 KXL48451.1 - 0.053 13.1 0.2 14 5.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain Dynamin_N PF00350.23 KXL48451.1 - 0.055 13.5 0.0 1.1 9.3 0.0 2.5 2 1 0 2 2 2 0 Dynamin family CLASP_N PF12348.8 KXL48451.1 - 0.057 13.0 0.0 0.59 9.7 0.0 2.2 2 0 0 2 2 2 0 CLASP N terminal AAA_25 PF13481.6 KXL48451.1 - 0.073 12.6 0.0 8.7 5.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain G-alpha PF00503.20 KXL48451.1 - 0.12 11.5 0.0 5.9 5.9 0.0 2.5 3 0 0 3 3 3 0 G-protein alpha subunit HEAT PF02985.22 KXL48451.1 - 0.13 12.6 0.6 34 5.0 0.0 4.4 5 0 0 5 5 3 0 HEAT repeat SR-25 PF10500.9 KXL48451.1 - 0.2 11.2 3.4 0.36 10.4 3.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Nup188 PF10487.9 KXL48451.1 - 0.27 9.1 1.2 0.27 9.1 0.2 1.4 2 0 0 2 2 2 0 Nucleoporin subcomplex protein binding to Pom34 HSP9_HSP12 PF04119.12 KXL48452.1 - 7.1e-17 61.5 3.9 7.9e-17 61.4 3.9 1.0 1 0 0 1 1 1 1 Heat shock protein 9/12 Zn_clus PF00172.18 KXL48453.1 - 8.6e-09 35.4 8.0 1.3e-08 34.8 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clostridium_P47 PF06597.11 KXL48456.1 - 0.26 9.9 5.9 0.29 9.8 5.9 1.0 1 0 0 1 1 1 0 Clostridium P-47 protein Psm4 PF17063.5 KXL48456.1 - 6 7.7 10.6 2.9 8.7 3.2 3.0 2 1 1 3 3 3 0 Phenol-soluble modulin alpha 4 peptide Synaptobrevin PF00957.21 KXL48457.1 - 4.7e-29 100.0 2.7 5.5e-29 99.8 2.7 1.1 1 0 0 1 1 1 1 Synaptobrevin MCU PF04678.13 KXL48457.1 - 0.022 14.9 0.1 0.027 14.6 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter RE_ApaLI PF09499.10 KXL48457.1 - 0.026 14.2 0.0 0.029 14.1 0.0 1.1 1 0 0 1 1 1 0 ApaLI-like restriction endonuclease Fzo_mitofusin PF04799.13 KXL48457.1 - 0.06 12.9 0.3 0.087 12.4 0.3 1.3 1 0 0 1 1 1 0 fzo-like conserved region Lyase_1 PF00206.20 KXL48458.1 - 9.9e-113 376.6 0.0 1.5e-112 376.1 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KXL48458.1 - 6.6e-21 74.5 0.1 1.5e-20 73.3 0.1 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus Sel1 PF08238.12 KXL48459.1 - 3.6e-45 151.4 26.3 5.9e-08 33.1 0.4 7.6 7 0 0 7 7 7 7 Sel1 repeat TPR_16 PF13432.6 KXL48459.1 - 0.015 16.0 4.9 0.015 16.0 4.9 5.5 5 1 1 6 6 6 0 Tetratricopeptide repeat Fasciclin PF02469.22 KXL48460.1 - 8.7e-50 168.2 0.0 7.2e-25 87.7 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain Tape_meas_lam_C PF09718.10 KXL48460.1 - 0.44 10.7 1.5 2.1 8.5 0.2 2.5 2 1 1 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) p450 PF00067.22 KXL48462.1 - 2.6e-22 79.2 0.0 1.2e-21 77.1 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 ASFV_L11L PF05293.11 KXL48465.1 - 0.0033 17.7 2.4 0.15 12.4 0.2 2.5 2 0 0 2 2 2 2 African swine fever virus (ASFV) L11L protein ABM PF03992.16 KXL48466.1 - 0.016 15.3 0.0 0.029 14.5 0.0 1.3 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Abhydrolase_1 PF00561.20 KXL48467.1 - 9.7e-18 64.7 0.1 1.7e-15 57.3 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXL48467.1 - 2.5e-14 54.4 6.0 3.3e-14 54.0 6.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXL48467.1 - 1.3e-12 47.5 0.0 1e-11 44.5 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 KXL48467.1 - 0.036 13.7 0.0 0.056 13.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF900 PF05990.12 KXL48467.1 - 0.065 12.7 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Ser_hydrolase PF06821.13 KXL48467.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Arm PF00514.23 KXL48468.1 - 5.1e-78 255.0 27.2 3.3e-12 46.0 0.0 11.3 11 1 1 12 12 12 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KXL48468.1 - 1.7e-19 70.0 10.8 7e-05 23.1 0.1 7.1 4 2 1 6 6 6 4 HEAT repeats HEAT PF02985.22 KXL48468.1 - 9.3e-18 62.8 10.5 0.061 13.6 0.0 9.3 9 0 0 9 9 9 4 HEAT repeat HEAT_EZ PF13513.6 KXL48468.1 - 1.2e-15 57.6 19.0 2.6e-05 24.6 0.2 8.5 5 2 4 9 9 9 4 HEAT-like repeat Arm_2 PF04826.13 KXL48468.1 - 2.5e-12 46.8 1.1 6.5e-07 29.1 0.1 2.6 1 1 0 2 2 2 2 Armadillo-like Adaptin_N PF01602.20 KXL48468.1 - 6.8e-12 44.7 4.2 5.3e-06 25.3 0.1 2.7 2 1 1 3 3 3 2 Adaptin N terminal region KAP PF05804.12 KXL48468.1 - 6.7e-10 37.8 0.2 1.5e-09 36.6 0.1 1.6 2 0 0 2 2 2 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 KXL48468.1 - 1.6e-06 27.7 0.1 0.0015 17.9 0.0 3.5 2 1 1 3 3 3 2 V-ATPase subunit H Cnd1 PF12717.7 KXL48468.1 - 1.6e-06 28.2 1.9 0.015 15.4 0.0 5.0 3 2 3 6 6 5 2 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 KXL48468.1 - 6.6e-05 23.0 0.9 8.3 6.6 0.0 5.3 2 1 6 8 8 8 2 V-ATPase subunit H DUF3361 PF11841.8 KXL48468.1 - 0.00014 21.8 5.1 1.7 8.5 0.0 4.4 2 1 4 6 6 6 1 Domain of unknown function (DUF3361) DUF5578 PF17741.1 KXL48468.1 - 0.00047 19.7 5.6 1.4 8.2 0.0 4.9 2 1 4 6 6 6 1 Family of unknown function (DUF5578) Atx10homo_assoc PF09759.9 KXL48468.1 - 0.0015 18.5 4.8 2.5 8.2 0.0 5.0 3 1 2 6 6 6 1 Spinocerebellar ataxia type 10 protein domain WAPL PF07814.13 KXL48468.1 - 0.0084 14.9 2.6 1.2 7.8 0.1 2.7 2 1 1 3 3 3 2 Wings apart-like protein regulation of heterochromatin RTP1_C1 PF10363.9 KXL48468.1 - 0.019 15.2 1.6 29 4.9 0.0 4.5 3 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 UNC45-central PF11701.8 KXL48468.1 - 0.089 12.8 0.2 29 4.6 0.0 3.1 2 1 1 3 3 3 0 Myosin-binding striated muscle assembly central IFRD PF05004.13 KXL48468.1 - 0.1 11.7 5.4 2.1 7.3 0.6 4.3 2 1 0 3 3 3 0 Interferon-related developmental regulator (IFRD) DrsE PF02635.15 KXL48468.1 - 0.12 12.8 0.0 0.35 11.3 0.0 1.8 1 0 0 1 1 1 0 DsrE/DsrF-like family HEAT_PBS PF03130.16 KXL48468.1 - 0.17 12.7 11.0 25 5.9 0.3 7.0 7 0 0 7 7 7 0 PBS lyase HEAT-like repeat RasGEF_N_2 PF14663.6 KXL48468.1 - 2.7 8.5 4.9 96 3.4 0.2 4.1 3 1 3 6 6 6 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain EamA PF00892.20 KXL48469.1 - 2.1e-09 37.7 41.3 9.7e-07 29.0 7.1 3.3 3 1 0 3 3 3 2 EamA-like transporter family DUF3955 PF13127.6 KXL48469.1 - 5.8e-07 29.2 3.0 5.8e-07 29.2 3.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3955) PUNUT PF16913.5 KXL48469.1 - 9.2e-06 25.1 10.6 9.2e-06 25.1 10.6 2.1 2 1 0 2 2 2 1 Purine nucleobase transmembrane transport SLC35F PF06027.12 KXL48469.1 - 9.9e-06 25.3 10.8 9.9e-06 25.3 10.8 2.1 2 0 0 2 2 2 1 Solute carrier family 35 Sugar_transport PF06800.12 KXL48469.1 - 0.00015 21.2 8.8 0.01 15.2 0.4 2.3 2 0 0 2 2 2 2 Sugar transport protein CitMHS_2 PF16980.5 KXL48469.1 - 0.0013 17.5 6.6 0.03 13.0 0.9 2.6 2 0 0 2 2 2 2 Putative citrate transport HemY_N PF07219.13 KXL48469.1 - 0.22 11.8 0.0 0.22 11.8 0.0 3.2 2 1 1 3 3 3 0 HemY protein N-terminus CRT-like PF08627.10 KXL48469.1 - 0.4 9.6 8.8 0.15 11.0 0.5 2.4 1 1 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 KXL48469.1 - 3.8 6.8 19.0 0.38 10.1 2.4 2.4 3 0 0 3 3 3 0 Triose-phosphate Transporter family Methyltransf_23 PF13489.6 KXL48470.1 - 6.6e-17 61.8 0.0 8.7e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL48470.1 - 4.8e-10 40.0 0.0 7.1e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL48470.1 - 9.2e-10 39.0 0.0 1.4e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL48470.1 - 5.9e-09 35.9 0.0 7.6e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL48470.1 - 7.6e-09 36.2 0.0 2.3e-08 34.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXL48470.1 - 1.9e-05 24.1 0.0 2.7e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family UPF0020 PF01170.18 KXL48470.1 - 0.033 13.9 0.0 0.045 13.4 0.0 1.1 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_21 PF05050.12 KXL48470.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase FkbM domain Spb1_C PF07780.12 KXL48471.1 - 1.9e-80 269.5 20.9 1.9e-80 269.5 20.9 2.6 2 0 0 2 2 2 1 Spb1 C-terminal domain FtsJ PF01728.19 KXL48471.1 - 2.2e-54 184.3 0.0 3.8e-54 183.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 KXL48471.1 - 1.8e-49 167.7 11.7 1.8e-49 167.7 11.7 4.9 3 1 0 4 4 4 1 Domain of unknown function (DUF3381) tRNA_bind_3 PF17176.4 KXL48471.1 - 0.02 15.2 0.1 0.053 13.8 0.1 1.7 1 0 0 1 1 1 0 tRNA-binding domain DUF922 PF06037.11 KXL48471.1 - 0.086 12.6 0.1 0.086 12.6 0.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF922) AAA PF00004.29 KXL48472.1 - 1.6e-08 35.0 2.7 1.5e-07 31.9 2.7 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KXL48472.1 - 2.2e-08 34.3 0.6 0.00086 19.3 0.0 3.1 2 1 1 3 3 3 2 Rad17 P-loop domain AAA_16 PF13191.6 KXL48472.1 - 1.8e-05 25.2 0.0 6e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 KXL48472.1 - 0.00074 18.8 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 KXL48472.1 - 0.0012 19.4 0.1 0.021 15.4 0.1 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KXL48472.1 - 0.0037 17.0 0.0 0.0069 16.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXL48472.1 - 0.006 16.9 1.2 0.006 16.9 1.2 2.5 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KXL48472.1 - 0.022 14.8 0.1 2.8 8.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 KXL48472.1 - 0.035 14.5 0.8 0.12 12.8 0.7 2.0 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 KXL48472.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_11 PF13086.6 KXL48472.1 - 0.13 12.0 3.4 13 5.5 2.5 2.4 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.22 KXL48472.1 - 0.13 12.6 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 KXL48472.1 - 0.2 11.7 0.5 0.43 10.6 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zn_clus PF00172.18 KXL48473.1 - 7e-07 29.3 10.2 1.2e-06 28.6 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DIOX_N PF14226.6 KXL48474.1 - 1.2e-19 71.2 0.1 1.8e-19 70.6 0.1 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXL48474.1 - 1.5e-13 51.1 0.0 7.5e-13 48.8 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ketoacyl-synt_C PF02801.22 KXL48474.1 - 0.054 13.5 0.0 0.092 12.8 0.0 1.3 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain PLDc_2 PF13091.6 KXL48476.1 - 9e-16 58.0 0.0 7.7e-06 25.8 0.0 4.2 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.22 KXL48476.1 - 2.1e-11 43.5 3.7 4.3e-06 26.7 0.1 3.0 3 0 0 3 3 3 2 Phospholipase D Active site motif DUF883 PF05957.13 KXL48476.1 - 0.75 10.4 2.0 4.1 8.1 0.1 3.0 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Phosducin PF02114.16 KXL48478.1 - 2.5e-10 39.7 0.0 1.8e-09 36.9 0.0 2.0 1 1 0 1 1 1 1 Phosducin WD40 PF00400.32 KXL48479.1 - 1e-38 130.6 16.4 2.4e-05 25.0 0.4 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL48479.1 - 2.8e-16 59.6 0.0 0.00039 20.7 0.1 4.9 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXL48479.1 - 7.3e-05 22.7 0.0 0.04 13.8 0.0 2.8 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KXL48479.1 - 0.00067 19.1 0.0 0.011 15.1 0.0 2.6 1 1 1 3 3 3 1 WD40-like domain zf-C2H2 PF00096.26 KXL48481.1 - 8.6e-08 32.2 26.3 0.13 12.7 0.3 6.8 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXL48481.1 - 4e-07 30.3 28.1 0.57 11.2 0.1 7.2 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KXL48481.1 - 0.0051 17.1 2.6 0.0051 17.1 2.6 4.0 3 2 0 3 3 3 1 C2H2 type zinc-finger (2 copies) AFOR_C PF01314.18 KXL48481.1 - 0.031 13.3 0.9 0.052 12.6 0.9 1.3 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 zf-met PF12874.7 KXL48481.1 - 1.5 9.3 8.1 3 8.4 1.7 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type IBR PF01485.21 KXL48481.1 - 1.8 8.8 15.6 1.3 9.3 0.1 3.9 2 1 2 4 4 4 0 IBR domain, a half RING-finger domain zf_C2H2_ZHX PF18387.1 KXL48481.1 - 6.1 6.6 9.7 2.1 8.0 0.6 3.3 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Cyanate_lyase PF02560.14 KXL48482.1 - 4.8e-34 116.0 0.1 7e-34 115.5 0.1 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_3 PF01381.22 KXL48482.1 - 0.0015 18.5 0.0 0.0023 18.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 KXL48482.1 - 0.0045 17.0 0.1 0.019 15.0 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_31 PF13560.6 KXL48482.1 - 0.091 13.1 0.0 0.14 12.6 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Atg14 PF10186.9 KXL48483.1 - 1.6e-15 57.0 2.9 2.9e-15 56.2 2.9 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 KXL48483.1 - 9.9e-14 51.0 0.1 1.5e-10 40.5 0.0 2.5 2 1 0 2 2 2 2 Vacuolar protein sorting 38 TEX13 PF15186.6 KXL48483.1 - 2.8 7.6 9.1 2.2 8.0 7.1 1.9 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family Mhr1 PF12829.7 KXL48484.1 - 6.7e-27 93.4 0.2 9.4e-27 92.9 0.2 1.2 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination L27_2 PF09045.10 KXL48484.1 - 0.092 12.7 0.5 0.32 11.0 0.2 2.0 2 0 0 2 2 2 0 L27_2 Rep_fac-A_3 PF08661.11 KXL48485.1 - 7.4e-25 87.3 0.0 8.3e-25 87.2 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 DUF1308 PF07000.11 KXL48486.1 - 1.2e-14 54.6 0.2 8.6e-14 51.8 0.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) DUF5614 PF18474.1 KXL48486.1 - 0.14 11.4 1.2 4.7 6.5 1.2 2.4 1 1 0 1 1 1 0 Family of unknown function (DUF5614) SRP9-21 PF05486.12 KXL48487.1 - 5.9e-35 119.5 0.4 5.9e-35 119.5 0.4 1.9 2 0 0 2 2 2 1 Signal recognition particle 9 kDa protein (SRP9) OAR PF03826.17 KXL48488.1 - 0.36 10.7 0.2 0.36 10.7 0.2 2.5 2 1 0 2 2 2 0 OAR domain Sugar_tr PF00083.24 KXL48489.1 - 4.2e-70 236.9 23.0 4.8e-70 236.7 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL48489.1 - 1.8e-17 63.3 26.8 3.8e-16 58.9 26.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily COesterase PF00135.28 KXL48490.1 - 1.5e-56 192.3 0.0 2.2e-56 191.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXL48490.1 - 7.1e-06 26.0 0.1 0.00046 20.1 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Apc15p PF05841.11 KXL48491.1 - 6.3e-13 49.6 0.3 6.3e-13 49.6 0.3 2.6 2 1 0 2 2 2 1 Apc15p protein HrcA PF01628.21 KXL48491.1 - 0.019 14.9 1.0 0.034 14.1 1.0 1.4 1 0 0 1 1 1 0 HrcA protein C terminal domain ThiF PF00899.21 KXL48492.1 - 4.6e-33 114.6 0.0 6.1e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 ThiF family E1_4HB PF16191.5 KXL48492.1 - 0.017 15.3 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 four-helix bundle Endomucin PF07010.12 KXL48495.1 - 0.0014 18.7 3.1 0.0014 18.7 3.1 2.0 2 0 0 2 2 2 1 Endomucin Rap1_C PF11626.8 KXL48495.1 - 0.052 13.6 0.1 0.1 12.7 0.1 1.5 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain CDC45 PF02724.14 KXL48495.1 - 0.43 8.8 4.5 0.57 8.4 4.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Fer4 PF00037.27 KXL48496.1 - 7.2e-14 50.9 15.4 6.3e-08 32.1 3.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KXL48496.1 - 1.8e-12 47.6 9.1 2.8e-12 47.0 9.1 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KXL48496.1 - 1.6e-10 41.7 6.9 6.9e-05 23.7 0.4 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 KXL48496.1 - 3.9e-10 39.7 3.8 0.00012 22.1 0.4 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 KXL48496.1 - 1.7e-08 34.8 2.4 0.00038 20.8 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KXL48496.1 - 2.1e-08 34.2 8.5 3.7e-08 33.4 8.5 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KXL48496.1 - 2.8e-08 33.7 21.1 4.9e-06 26.6 12.1 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KXL48496.1 - 1.6e-06 27.9 17.1 0.00041 20.3 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KXL48496.1 - 4.8e-06 26.3 12.1 0.01 15.9 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KXL48496.1 - 1.2e-05 25.5 11.6 0.00037 20.8 2.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KXL48496.1 - 0.00036 21.0 11.5 0.034 14.7 12.4 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 KXL48496.1 - 0.074 13.6 14.9 0.77 10.4 4.3 2.6 2 1 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 KXL48496.1 - 0.12 12.6 9.1 1 9.6 1.5 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 KXL48496.1 - 0.14 12.3 5.7 0.71 10.0 0.5 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_3 PF12798.7 KXL48496.1 - 0.25 12.4 15.5 0.44 11.6 3.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 KXL48496.1 - 0.86 10.5 11.7 2.9 8.8 1.7 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 KXL48496.1 - 2.5 8.4 12.6 1.1 9.6 0.3 2.7 2 1 1 3 3 3 0 c-SKI Smad4 binding domain PAP_assoc PF03828.19 KXL48497.1 - 0.00026 21.1 0.1 0.0043 17.2 0.1 2.3 1 1 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KXL48497.1 - 0.067 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyltransferase domain Glyco_transf_20 PF00982.21 KXL48498.1 - 4e-147 490.7 0.0 5.6e-147 490.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KXL48498.1 - 1.1e-79 266.9 0.0 1.6e-79 266.3 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.11 KXL48498.1 - 0.081 12.6 0.1 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain BRD4_CDT PF17105.5 KXL48498.1 - 0.11 12.1 0.0 0.42 10.2 0.0 2.0 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 TilS_C PF11734.8 KXL48500.1 - 0.16 11.4 0.2 0.45 10.0 0.1 1.8 2 0 0 2 2 2 0 TilS substrate C-terminal domain Sas10 PF09368.10 KXL48501.1 - 7.7e-29 100.0 7.1 2.4e-28 98.4 7.1 1.9 1 0 0 1 1 1 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 KXL48501.1 - 1.2e-05 25.9 0.0 4e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 Sas10/Utp3/C1D family CH PF00307.31 KXL48504.1 - 4.8e-68 226.2 0.0 1.4e-17 63.8 0.1 4.3 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 KXL48504.1 - 2.7e-05 24.5 2.0 6.6e-05 23.3 0.2 2.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 KXL48504.1 - 0.0018 17.7 1.7 0.61 9.8 0.3 3.5 3 0 0 3 3 3 1 EF hand CAMSAP_CH PF11971.8 KXL48504.1 - 0.0055 16.5 0.0 5.2 7.0 0.0 4.0 5 0 0 5 5 5 1 CAMSAP CH domain EF-hand_6 PF13405.6 KXL48504.1 - 0.077 13.0 4.2 0.27 11.3 0.1 3.1 3 0 0 3 3 3 0 EF-hand domain DUF1907 PF08925.11 KXL48505.1 - 3.1e-107 358.2 0.0 3.6e-107 358.0 0.0 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) RED_N PF07808.13 KXL48506.1 - 6.7e-07 29.1 4.5 1.6e-06 27.9 4.5 1.7 1 0 0 1 1 1 1 RED-like protein N-terminal region TssO PF17561.2 KXL48507.1 - 0.095 12.8 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssO AA_permease_2 PF13520.6 KXL48511.1 - 5.2e-53 180.4 56.5 6.4e-53 180.1 56.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXL48511.1 - 3e-24 85.5 49.4 3.9e-24 85.1 49.4 1.1 1 0 0 1 1 1 1 Amino acid permease CrgA PF06781.12 KXL48511.1 - 0.23 11.5 5.2 0.6 10.2 2.6 3.0 2 0 0 2 2 2 0 Cell division protein CrgA Methyltransf_25 PF13649.6 KXL48512.1 - 3e-16 59.9 0.0 5.2e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL48512.1 - 8.2e-16 58.4 0.0 1.4e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL48512.1 - 1.7e-14 53.9 0.0 2.5e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXL48512.1 - 7.6e-11 42.1 0.0 9.6e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL48512.1 - 4.7e-10 40.1 0.0 7.8e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXL48512.1 - 2.8e-08 33.4 0.0 5.3e-08 32.5 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Pox_MCEL PF03291.16 KXL48512.1 - 7.8e-07 28.5 0.1 4.2e-06 26.1 0.1 2.0 1 1 0 1 1 1 1 mRNA capping enzyme PrmA PF06325.13 KXL48512.1 - 2.6e-05 23.8 0.0 3.7e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KXL48512.1 - 0.0001 21.9 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 KXL48512.1 - 0.00013 21.0 0.0 0.00045 19.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) NodS PF05401.11 KXL48512.1 - 0.00063 19.4 0.0 0.00092 18.9 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MetW PF07021.12 KXL48512.1 - 0.0088 15.7 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Rsm22 PF09243.10 KXL48512.1 - 0.022 14.0 0.0 0.028 13.7 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 CMAS PF02353.20 KXL48512.1 - 0.031 13.6 0.0 0.043 13.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Bmt2 PF11968.8 KXL48512.1 - 0.053 13.4 0.0 0.082 12.7 0.0 1.2 1 0 0 1 1 1 0 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 WD40 PF00400.32 KXL48513.1 - 3.7e-26 90.8 5.7 2.3e-09 37.7 0.0 4.4 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL48513.1 - 2.1e-09 37.6 0.0 0.0015 18.8 0.1 3.4 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXL48513.1 - 8.2e-09 34.9 0.2 0.0013 17.7 0.1 2.8 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KXL48513.1 - 0.0018 17.0 0.2 0.23 10.1 0.0 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 KXL48513.1 - 0.023 14.0 0.4 2.3 7.4 0.0 2.6 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 KXL48513.1 - 0.032 14.2 0.2 6 6.9 0.0 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KXL48513.1 - 0.079 11.5 0.0 0.1 11.1 0.0 1.1 1 0 0 1 1 1 0 Cytochrome D1 heme domain SAS4 PF15460.6 KXL48515.1 - 0.047 13.8 0.3 0.11 12.7 0.3 1.5 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 C6_DPF PF10170.9 KXL48516.1 - 0.63 10.4 5.7 1.6 9.1 5.8 1.8 1 1 0 1 1 1 0 Cysteine-rich domain NifU_N PF01592.16 KXL48517.1 - 5e-54 181.9 0.0 6.4e-54 181.5 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain TSCPD PF12637.7 KXL48517.1 - 0.019 15.2 0.0 0.038 14.2 0.0 1.4 1 0 0 1 1 1 0 TSCPD domain Methyltransf_23 PF13489.6 KXL48518.1 - 3.5e-20 72.5 0.0 5e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL48518.1 - 2.2e-13 50.7 0.0 5.7e-13 49.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL48518.1 - 4.3e-09 36.9 0.0 1.3e-08 35.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL48518.1 - 1.7e-08 35.1 0.0 2e-07 31.7 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL48518.1 - 3.4e-07 30.2 0.0 9e-06 25.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KXL48518.1 - 0.00012 21.5 0.0 0.00026 20.4 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_4 PF02390.17 KXL48518.1 - 0.00033 20.2 0.0 0.013 15.0 0.0 2.4 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 KXL48518.1 - 0.0012 18.4 0.0 0.017 14.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_16 PF10294.9 KXL48518.1 - 0.0026 17.5 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase FtsJ PF01728.19 KXL48518.1 - 0.0036 17.4 0.0 0.0058 16.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.20 KXL48518.1 - 0.0053 16.1 0.0 0.012 14.9 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KXL48518.1 - 0.049 13.0 0.0 0.12 11.7 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KXL48518.1 - 0.088 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Mito_carr PF00153.27 KXL48520.1 - 1.9e-57 191.2 5.9 5e-19 68.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CoA_trans PF01144.23 KXL48521.1 - 8.5e-102 339.1 2.0 6e-62 208.9 0.2 2.1 2 0 0 2 2 2 2 Coenzyme A transferase Fungal_trans PF04082.18 KXL48522.1 - 4.5e-09 35.7 0.2 8.3e-09 34.9 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL48522.1 - 5.2e-06 26.5 15.9 5.4e-06 26.4 13.0 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Vps39_2 PF10367.9 KXL48522.1 - 0.12 12.9 2.5 0.21 12.1 1.0 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 OAR PF03826.17 KXL48522.1 - 3 7.8 5.7 6.6 6.7 0.1 2.6 2 0 0 2 2 2 0 OAR domain FRQ PF09421.10 KXL48523.1 - 5.3e-122 408.8 44.7 1e-119 401.2 44.7 2.6 1 1 0 1 1 1 1 Frequency clock protein CYSTM PF12734.7 KXL48524.1 - 0.036 14.4 28.2 0.036 14.4 28.2 3.7 2 2 0 2 2 2 0 Cysteine-rich TM module stress tolerance P68HR PF08061.11 KXL48524.1 - 0.85 9.8 9.8 1.8 8.7 1.0 2.6 2 0 0 2 2 2 0 P68HR (NUC004) repeat RNA_pol_Rpb5_C PF01191.19 KXL48525.1 - 8.4e-33 112.1 0.1 1.6e-32 111.2 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KXL48525.1 - 3.8e-26 91.5 0.0 7.3e-26 90.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 KXL48525.1 - 0.0011 18.9 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease LCM PF04072.14 KXL48526.1 - 6.5e-24 84.9 0.0 1.1e-23 84.2 0.0 1.4 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase DLH PF01738.18 KXL48527.1 - 2.5e-33 115.5 0.0 3e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KXL48527.1 - 0.003 17.3 0.0 0.081 12.6 0.0 2.4 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF915 PF06028.11 KXL48527.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) UCH PF00443.29 KXL48528.1 - 1.3e-38 133.0 0.0 1.7e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 KXL48528.1 - 4.1e-25 87.3 1.6 1.8e-23 82.1 0.1 2.6 2 0 0 2 2 2 1 Variant UBP zinc finger zf-UBP PF02148.19 KXL48528.1 - 2.6e-22 78.9 17.6 1e-19 70.6 0.8 3.5 4 0 0 4 4 4 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 KXL48528.1 - 3.2e-20 71.6 0.0 3.4e-09 36.4 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 KXL48528.1 - 1.5e-17 64.2 0.1 1.3e-14 54.5 0.0 3.1 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase zf-RING_UBOX PF13445.6 KXL48528.1 - 0.0035 17.3 9.9 0.2 11.7 2.1 3.9 3 0 0 3 3 3 1 RING-type zinc-finger UBA_4 PF14555.6 KXL48528.1 - 0.0041 16.9 0.0 0.0081 16.0 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain zf-C3HC4_2 PF13923.6 KXL48528.1 - 0.012 15.5 1.6 0.012 15.5 1.6 3.6 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.32 KXL48529.1 - 3.7e-11 43.4 0.6 0.1 13.5 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat Atg8 PF02991.16 KXL48529.1 - 0.087 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like WD40_like PF17005.5 KXL48529.1 - 0.22 10.8 0.0 0.63 9.3 0.0 1.8 1 1 0 1 1 1 0 WD40-like domain Histone_HNS PF00816.21 KXL48529.1 - 5.2 7.9 8.1 5.9 7.8 1.5 3.3 3 0 0 3 3 3 0 H-NS histone family ADH_zinc_N PF00107.26 KXL48530.1 - 2.4e-27 95.5 0.2 1.8e-26 92.7 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXL48530.1 - 8.5e-21 73.9 2.8 1.5e-20 73.1 2.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KXL48530.1 - 6.1e-10 38.9 0.0 1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KXL48530.1 - 1.9e-06 28.9 0.0 5.2e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXL48530.1 - 0.0065 15.8 0.1 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KXL48530.1 - 0.085 12.4 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Erg28 PF03694.13 KXL48531.1 - 1.2e-20 73.9 3.4 1.2e-20 73.9 3.4 1.5 1 1 1 2 2 2 1 Erg28 like protein ThiF PF00899.21 KXL48532.1 - 1.2e-58 198.3 0.0 1.8e-58 197.8 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 KXL48532.1 - 4.4e-09 36.8 0.0 1.5e-08 35.1 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain NAD_binding_7 PF13241.6 KXL48532.1 - 0.028 14.8 0.0 0.055 13.9 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Hydantoinase_B PF02538.14 KXL48533.1 - 2.1e-222 739.1 0.4 3e-222 738.6 0.4 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KXL48533.1 - 1.7e-102 342.6 0.1 4.5e-102 341.2 0.1 1.7 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KXL48533.1 - 2.2e-62 209.9 0.4 1.1e-60 204.4 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region PALP PF00291.25 KXL48534.1 - 2.6e-50 171.5 0.1 3.2e-50 171.2 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Sugar_tr PF00083.24 KXL48535.1 - 1.1e-93 314.6 28.9 1.3e-93 314.3 28.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL48535.1 - 2.1e-21 76.3 40.4 3.5e-17 62.4 19.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_PK PF05891.12 KXL48535.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase S-AdoMet_synt_C PF02773.16 KXL48536.1 - 6.9e-68 226.9 0.0 1.4e-67 225.9 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KXL48536.1 - 1.8e-47 160.5 0.0 3.5e-47 159.6 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KXL48536.1 - 1.5e-43 147.5 0.2 3.4e-43 146.4 0.2 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 KXL48536.1 - 0.024 13.4 0.4 0.38 9.5 0.1 2.2 1 1 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) Thioesterase PF00975.20 KXL48537.1 - 7.7e-23 81.8 0.0 1.1e-22 81.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 KXL48537.1 - 0.00022 21.9 0.0 0.0006 20.5 0.0 1.6 1 1 0 2 2 2 1 Alpha/beta hydrolase family PP-binding PF00550.25 KXL48537.1 - 0.00071 19.9 0.0 0.0018 18.6 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF2974 PF11187.8 KXL48537.1 - 0.02 14.5 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 KXL48537.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KXL48537.1 - 0.16 11.8 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Asp PF00026.23 KXL48538.1 - 1e-107 360.2 0.0 1.2e-107 360.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXL48538.1 - 5e-15 56.2 0.8 2.1e-13 50.9 0.3 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KXL48538.1 - 0.00071 20.2 0.0 3.4 8.4 0.0 3.5 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KXL48538.1 - 0.00076 20.0 0.0 1.4 9.6 0.0 2.8 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KXL48538.1 - 0.001 18.8 0.0 0.0055 16.5 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Glyco_transf_28 PF03033.20 KXL48539.1 - 2.5e-28 98.9 0.0 6.9e-28 97.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 KXL48539.1 - 1e-25 89.8 0.4 2.5e-15 56.4 0.0 3.4 3 0 0 3 3 3 3 GRAM domain PH PF00169.29 KXL48539.1 - 6.7e-12 45.8 0.0 1.7e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 PH domain UDPGT PF00201.18 KXL48539.1 - 0.00062 18.7 0.0 0.001 18.0 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_8 PF15409.6 KXL48539.1 - 0.0033 17.7 0.0 0.007 16.6 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 KXL48539.1 - 0.025 14.9 0.3 0.1 12.9 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain PH_11 PF15413.6 KXL48539.1 - 0.039 14.4 0.3 0.84 10.1 0.3 2.6 1 1 0 1 1 1 0 Pleckstrin homology domain NIF PF03031.18 KXL48540.1 - 8e-26 90.7 0.0 1.8e-25 89.5 0.0 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 KXL48540.1 - 1.7e-07 31.5 0.0 4e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KXL48540.1 - 0.0014 19.0 0.0 0.0042 17.5 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 KXL48540.1 - 0.0025 17.7 0.1 0.006 16.5 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain RTT107_BRCT_5 PF16770.5 KXL48540.1 - 0.018 14.9 0.0 0.052 13.4 0.0 1.8 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain F-box-like PF12937.7 KXL48541.1 - 0.00016 21.5 0.0 0.00045 20.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like Glyco_trans_2_3 PF13632.6 KXL48543.1 - 1.9e-23 83.4 3.0 1.9e-23 83.4 3.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 DUF2418 PF10332.9 KXL48543.1 - 2.9 8.5 6.3 9.3 6.9 1.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2418) Sec23_trunk PF04811.15 KXL48544.1 - 2.5e-69 233.6 0.0 3.7e-69 233.0 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KXL48544.1 - 1.7e-24 85.6 0.1 7.4e-24 83.5 0.0 2.2 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KXL48544.1 - 2.9e-17 63.2 0.0 7.4e-17 61.9 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KXL48544.1 - 6.9e-16 58.0 5.2 1.3e-15 57.2 5.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KXL48544.1 - 2.3e-08 33.8 0.1 8e-08 32.1 0.0 2.0 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KXL48544.1 - 0.017 14.5 0.3 0.038 13.4 0.3 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain MFS_1 PF07690.16 KXL48545.1 - 1.9e-37 129.1 48.4 3.9e-33 114.9 33.7 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 KXL48545.1 - 0.011 14.6 0.2 0.011 14.6 0.2 2.5 2 0 0 2 2 2 0 LacY proton/sugar symporter XhlA PF10779.9 KXL48545.1 - 2 8.7 3.3 14 6.0 0.1 2.6 2 0 0 2 2 2 0 Haemolysin XhlA AA_permease_2 PF13520.6 KXL48546.1 - 8.4e-56 189.6 47.9 1e-55 189.3 47.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXL48546.1 - 5.8e-13 48.3 44.1 9.9e-13 47.5 44.1 1.3 1 1 0 1 1 1 1 Amino acid permease RVT_1 PF00078.27 KXL48547.1 - 2e-05 24.2 0.1 0.02 14.4 0.0 2.8 1 1 2 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF469 PF04320.14 KXL48547.1 - 0.084 13.7 0.0 0.09 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein with unknown function (DUF469) HTH_Tnp_Tc5 PF03221.16 KXL48548.1 - 5.2e-10 39.2 0.0 6.8e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CPSase_L_D2 PF02786.17 KXL48551.1 - 1.8e-82 275.9 0.1 2.9e-82 275.3 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 KXL48551.1 - 2.2e-70 236.4 0.1 5.2e-70 235.2 0.0 1.7 2 0 0 2 2 2 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 KXL48551.1 - 2.8e-39 134.1 0.0 5.5e-39 133.1 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KXL48551.1 - 5e-31 107.0 0.0 1.8e-30 105.2 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 KXL48551.1 - 9.7e-27 94.2 0.0 2.1e-26 93.1 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 KXL48551.1 - 9e-18 63.9 4.8 1.4e-17 63.3 3.4 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KXL48551.1 - 8.3e-10 38.3 1.9 8.3e-06 25.5 0.8 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 KXL48551.1 - 1.9e-09 37.4 0.0 4e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KXL48551.1 - 9.7e-06 25.3 0.1 2.2e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KXL48551.1 - 2e-05 24.7 0.0 5e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 KXL48551.1 - 0.00045 20.9 0.5 1.6 9.5 0.2 3.0 3 0 0 3 3 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 KXL48551.1 - 0.0008 18.7 0.2 0.088 12.0 0.2 2.4 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion RimK PF08443.11 KXL48551.1 - 0.0054 16.4 0.0 0.026 14.1 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 KXL48551.1 - 0.006 16.2 0.1 0.046 13.3 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 KXL48551.1 - 0.028 14.2 0.0 0.059 13.1 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 KXL48551.1 - 0.12 11.6 0.0 0.31 10.2 0.0 1.6 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp GCV_H PF01597.19 KXL48551.1 - 0.18 11.7 0.5 0.58 10.1 0.3 1.9 1 1 0 1 1 1 0 Glycine cleavage H-protein RnfC_N PF13375.6 KXL48551.1 - 0.2 11.7 1.1 0.81 9.7 1.1 2.0 1 1 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Peptidase_M24 PF00557.24 KXL48553.1 - 1.7e-40 139.0 0.1 2.2e-40 138.6 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3323 PF11796.8 KXL48553.1 - 0.18 11.7 0.7 0.33 10.8 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) Pyr_redox_2 PF07992.14 KXL48554.1 - 0.00041 19.7 0.1 0.0067 15.7 0.2 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXL48554.1 - 0.00056 19.1 0.0 0.0013 17.9 0.0 1.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXL48554.1 - 0.017 15.1 0.0 4 7.4 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KXL48554.1 - 0.09 12.0 0.0 3 7.0 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase AA_permease PF00324.21 KXL48555.1 - 2.7e-113 379.1 45.1 3.3e-113 378.8 45.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXL48555.1 - 8.4e-33 113.8 48.1 1e-32 113.5 48.1 1.0 1 0 0 1 1 1 1 Amino acid permease Lactonase PF10282.9 KXL48556.1 - 9e-15 54.8 0.0 1.5e-14 54.0 0.0 1.4 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller AICARFT_IMPCHas PF01808.18 KXL48558.1 - 1.5e-91 307.0 0.0 2.3e-91 306.3 0.0 1.3 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 KXL48558.1 - 1.6e-23 82.7 0.0 3e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain EF-hand_4 PF12763.7 KXL48561.1 - 1e-28 99.3 0.0 5e-14 52.1 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.20 KXL48561.1 - 1.5e-07 31.0 2.2 2.3e-07 30.4 0.8 2.2 2 0 0 2 2 2 1 WH2 motif EF-hand_7 PF13499.6 KXL48561.1 - 7.9e-06 26.2 2.6 0.0019 18.6 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KXL48561.1 - 1.2e-05 24.5 0.0 0.015 14.8 0.0 3.3 3 0 0 3 3 3 2 EF hand DUF1720 PF08226.11 KXL48561.1 - 0.011 16.2 32.9 0.011 16.2 32.9 8.1 6 2 2 8 8 8 0 Domain of unknown function (DUF1720) EF-hand_6 PF13405.6 KXL48561.1 - 0.014 15.3 0.2 10 6.3 0.0 3.6 4 0 0 4 4 4 0 EF-hand domain EF-hand_8 PF13833.6 KXL48561.1 - 0.19 11.6 1.0 1.3 9.0 0.0 2.8 4 0 0 4 4 4 0 EF-hand domain pair Laminin_I PF06008.14 KXL48562.1 - 0.15 11.8 2.8 0.28 10.8 2.8 1.4 1 0 0 1 1 1 0 Laminin Domain I KELK PF15796.5 KXL48562.1 - 0.65 10.5 8.2 2.3 8.7 8.2 1.9 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase AIG2_2 PF13772.6 KXL48563.1 - 0.00066 20.0 0.0 0.0039 17.6 0.0 2.1 2 0 0 2 2 2 1 AIG2-like family CLZ PF16526.5 KXL48564.1 - 0.00076 19.8 3.1 0.0009 19.6 3.1 1.1 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DHR10 PF18595.1 KXL48564.1 - 0.0041 17.2 5.3 0.0048 16.9 5.3 1.2 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain ATG16 PF08614.11 KXL48564.1 - 0.005 17.1 5.8 0.0052 17.0 5.8 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Helo_like_N PF17111.5 KXL48564.1 - 0.025 14.0 1.5 0.028 13.8 1.5 1.1 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins DUF1045 PF06299.12 KXL48564.1 - 0.071 13.1 2.1 0.1 12.6 2.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1045) APG6_N PF17675.1 KXL48564.1 - 0.099 13.2 7.7 0.11 13.0 7.7 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region OmpH PF03938.14 KXL48564.1 - 0.23 11.8 7.3 0.3 11.4 7.3 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) MbeB_N PF04837.12 KXL48564.1 - 0.82 10.0 8.3 0.094 13.0 4.1 1.6 2 0 0 2 2 2 0 MbeB-like, N-term conserved region IF-2B PF01008.17 KXL48565.1 - 9.3e-74 248.2 0.7 1.1e-73 247.9 0.7 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Aldo_ket_red PF00248.21 KXL48566.1 - 1.3e-28 100.1 0.3 8.8e-17 61.2 0.0 3.0 1 1 2 3 3 3 3 Aldo/keto reductase family Peptidase_C48 PF02902.19 KXL48567.1 - 4.3e-19 69.2 0.0 1.8e-18 67.2 0.0 1.9 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF4951 PF16309.5 KXL48567.1 - 0.015 15.4 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 Domian of unknown function (DUF4951) Myb_DNA-binding PF00249.31 KXL48569.1 - 1.5e-24 85.9 3.2 0.0002 21.5 0.1 5.3 5 0 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXL48569.1 - 4.7e-17 62.0 2.6 0.00023 21.3 0.2 5.1 4 1 1 5 5 5 4 Myb-like DNA-binding domain HTH_38 PF13936.6 KXL48569.1 - 1.4e-05 24.8 9.1 0.042 13.6 0.0 3.9 4 0 0 4 4 4 3 Helix-turn-helix domain HTH_7 PF02796.15 KXL48569.1 - 0.00064 19.7 0.2 0.058 13.5 0.0 3.4 4 0 0 4 4 4 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 KXL48569.1 - 0.0021 17.8 3.3 1.1 9.1 0.1 3.4 4 0 0 4 4 4 2 Homeodomain-like domain HTH_32 PF13565.6 KXL48569.1 - 0.0054 17.3 24.8 0.72 10.5 0.6 5.1 1 1 4 5 5 5 2 Homeodomain-like domain Myb_DNA-bind_7 PF15963.5 KXL48569.1 - 0.0073 16.2 0.3 0.43 10.5 0.0 3.3 3 1 1 4 4 4 1 Myb DNA-binding like DUF2285 PF10074.9 KXL48569.1 - 0.047 14.3 0.5 0.047 14.3 0.5 3.1 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2285) Sigma70_r4_2 PF08281.12 KXL48569.1 - 0.049 13.3 0.1 4.8 6.9 0.0 3.4 4 0 0 4 4 4 0 Sigma-70, region 4 DUF2481 PF10654.9 KXL48569.1 - 0.16 12.0 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2481) eIF2_C PF09173.11 KXL48570.1 - 3.3e-35 120.2 0.4 7.3e-35 119.1 0.4 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KXL48570.1 - 6.6e-24 84.5 0.3 4.8e-23 81.7 0.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KXL48570.1 - 1.2e-11 44.9 0.3 2.4e-11 43.9 0.3 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 KXL48570.1 - 0.0019 18.1 0.1 0.018 15.0 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KXL48570.1 - 0.0037 17.3 0.0 0.0078 16.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 KXL48570.1 - 0.042 13.9 0.1 0.089 12.8 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain PMM PF03332.13 KXL48571.1 - 5.4e-102 340.2 0.2 6.4e-102 340.0 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 KXL48571.1 - 1e-05 25.4 0.0 5.9e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KXL48571.1 - 0.0092 15.5 0.0 1.2 8.6 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.7 KXL48571.1 - 0.05 14.0 0.0 7 7.0 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Fcf1 PF04900.12 KXL48572.1 - 3.3e-36 123.7 0.2 7.6e-36 122.5 0.2 1.6 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 KXL48572.1 - 3.6e-12 46.6 0.3 2.8e-11 43.8 0.0 1.9 2 0 0 2 2 2 1 PIN like domain Glyco_hydro_7 PF00840.20 KXL48572.1 - 0.19 10.4 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 7 DUF3431 PF11913.8 KXL48576.1 - 7.3e-90 300.5 0.4 1.2e-89 299.7 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3431) MtrF PF09472.10 KXL48578.1 - 0.045 13.2 1.8 0.087 12.2 1.8 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) TRAPPC9-Trs120 PF08626.11 KXL48578.1 - 0.3 8.4 1.0 0.37 8.1 1.0 1.0 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Glyco_hydro_17 PF00332.18 KXL48580.1 - 1.9e-05 24.4 5.3 5.9e-05 22.8 4.9 2.2 1 1 1 2 2 2 1 Glycosyl hydrolases family 17 Orn_Arg_deC_N PF02784.16 KXL48581.1 - 3.4e-82 275.5 0.0 5e-82 275.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KXL48581.1 - 2.1e-19 69.6 0.0 3e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 KXL48581.1 - 0.00012 21.6 0.0 0.00021 20.8 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel ArfGap PF01412.18 KXL48582.1 - 2.4e-39 134.0 0.1 8.2e-39 132.3 0.1 1.9 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UBA PF00627.31 KXL48582.1 - 0.08 12.9 1.9 0.14 12.1 0.1 2.2 2 0 0 2 2 2 0 UBA/TS-N domain FMO-like PF00743.19 KXL48584.1 - 1.8e-15 56.4 0.5 2.8e-14 52.4 0.3 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXL48584.1 - 9.1e-11 41.8 0.0 9.3e-10 38.6 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXL48584.1 - 1.6e-05 24.3 0.0 0.0086 15.3 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXL48584.1 - 2.8e-05 23.4 0.0 0.0003 20.0 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KXL48584.1 - 0.00072 19.2 1.0 0.26 10.8 0.0 2.8 2 1 1 3 3 3 2 FAD dependent oxidoreductase Shikimate_DH PF01488.20 KXL48584.1 - 0.054 13.6 0.0 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 KXL48584.1 - 0.15 11.3 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family LBR_tudor PF09465.10 KXL48584.1 - 0.2 11.5 0.9 0.53 10.1 0.2 2.1 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain Diphthami_syn_2 PF01902.17 KXL48585.1 - 2.9e-25 89.1 0.0 4.4e-23 81.9 0.0 2.6 2 1 0 2 2 2 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 KXL48585.1 - 7.1e-14 51.9 0.0 4.7e-07 29.8 0.0 3.6 3 1 0 3 3 3 2 Endoribonuclease L-PSP Glyco_hydro_79C PF16862.5 KXL48586.1 - 2.6e-23 82.9 0.2 1e-22 80.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain AAA PF00004.29 KXL48587.1 - 2.4e-15 57.1 0.0 4.2e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KXL48587.1 - 0.056 13.2 0.0 0.087 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_membrane PF00664.23 KXL48588.1 - 7.3e-55 186.5 31.0 1.5e-35 123.2 16.6 3.1 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXL48588.1 - 9e-46 155.8 0.0 5.2e-27 95.0 0.1 3.1 3 0 0 3 3 2 2 ABC transporter Zeta_toxin PF06414.12 KXL48588.1 - 2.7e-06 26.8 0.1 0.00041 19.7 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 KXL48588.1 - 1e-05 26.0 0.1 0.093 13.1 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 KXL48588.1 - 5.3e-05 22.7 0.9 1.4 8.3 0.3 3.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KXL48588.1 - 7.9e-05 22.7 4.1 0.099 12.7 0.4 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXL48588.1 - 0.00025 21.0 0.8 0.14 12.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KXL48588.1 - 0.00028 20.6 1.7 0.19 11.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.23 KXL48588.1 - 0.0017 18.4 4.3 0.044 13.8 0.3 2.7 2 0 0 2 2 2 1 Dynamin family AAA_21 PF13304.6 KXL48588.1 - 0.0083 16.0 3.1 1.9 8.2 0.2 3.3 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system EI24 PF07264.11 KXL48588.1 - 0.019 15.2 15.5 0.44 10.8 1.7 3.1 2 2 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) MeaB PF03308.16 KXL48588.1 - 0.025 13.6 3.2 1.9 7.4 0.1 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 KXL48588.1 - 0.048 13.9 3.5 8.6 6.6 0.3 3.1 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 KXL48588.1 - 0.052 13.8 0.3 6.5 7.0 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ploopntkinase3 PF18751.1 KXL48588.1 - 0.065 13.1 0.2 12 5.8 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_30 PF13604.6 KXL48588.1 - 0.18 11.5 4.2 6.2 6.5 0.4 2.7 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 KXL48588.1 - 0.18 12.3 1.4 4.1 7.9 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KXL48588.1 - 0.23 11.0 1.1 2.2 7.8 0.2 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF87 PF01935.17 KXL48588.1 - 0.59 10.2 10.2 0.22 11.6 0.7 2.8 2 1 1 3 3 3 0 Helicase HerA, central domain AAA_28 PF13521.6 KXL48588.1 - 0.94 9.7 3.4 0.97 9.7 0.2 2.7 3 0 0 3 3 3 0 AAA domain Pex24p PF06398.11 KXL48588.1 - 0.99 8.3 3.8 8.5 5.2 0.5 2.4 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin ATP_bind_1 PF03029.17 KXL48588.1 - 1.2 8.9 4.2 15 5.3 0.7 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 KXL48588.1 - 1.6 9.2 8.3 7.9 6.9 0.0 3.6 4 0 0 4 4 4 0 AAA domain Rrn6 PF10214.9 KXL48588.1 - 5.8 5.3 8.1 8.7 4.7 8.1 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor AlaDh_PNT_N PF05222.15 KXL48589.1 - 2.6e-29 102.3 0.0 3.8e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 KXL48589.1 - 0.001 18.4 0.0 0.0046 16.3 0.0 2.0 1 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ThiC-associated PF13667.6 KXL48589.1 - 0.017 14.9 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 ThiC-associated domain tRNA-synt_1g PF09334.11 KXL48590.1 - 3.4e-93 312.5 0.1 1.1e-91 307.5 0.1 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KXL48590.1 - 9.9e-23 80.2 3.5 2.9e-10 39.0 0.0 3.6 1 1 3 4 4 4 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KXL48590.1 - 9.6e-09 35.0 0.1 0.00019 20.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 KXL48590.1 - 0.00035 20.6 0.0 0.0021 18.1 0.0 2.1 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA F-box-like PF12937.7 KXL48591.1 - 5.8e-06 26.1 0.3 2.6e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 F-box-like DUF5508 PF17621.2 KXL48591.1 - 0.044 12.9 0.0 0.051 12.7 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5508) Peptidase_M48_N PF16491.5 KXL48593.1 - 1.6e-60 204.1 8.0 2.7e-60 203.4 8.0 1.4 1 0 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 KXL48593.1 - 6.9e-40 136.9 0.0 1.3e-39 136.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 KXL48593.1 - 0.029 13.6 0.2 0.078 12.2 0.2 1.7 1 1 0 1 1 1 0 BlaR1 peptidase M56 WW PF00397.26 KXL48594.1 - 4.8e-11 42.6 0.5 1e-10 41.5 0.5 1.6 1 0 0 1 1 1 1 WW domain PhoD PF09423.10 KXL48594.1 - 0.08 11.9 0.1 0.14 11.1 0.1 1.3 1 0 0 1 1 1 0 PhoD-like phosphatase Sec10 PF07393.11 KXL48595.1 - 5.9e-139 464.6 0.0 7.8e-139 464.2 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.33 KXL48595.1 - 4.8e-07 29.5 0.1 1.6e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KXL48595.1 - 7.2e-07 29.0 0.0 1.7e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like DUF5302 PF17227.2 KXL48595.1 - 0.34 11.9 2.1 0.91 10.6 2.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5302) Syja_N PF02383.18 KXL48597.1 - 9.5e-77 258.4 0.0 1.6e-76 257.7 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 KXL48597.1 - 5.4e-09 35.9 0.0 1e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family OPT PF03169.15 KXL48598.1 - 3.4e-89 300.1 44.5 4.5e-89 299.8 44.5 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Prenyltrans PF00432.21 KXL48599.1 - 7.5e-30 102.4 5.6 9.8e-09 34.8 0.0 6.4 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KXL48599.1 - 0.00097 18.3 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain TED_complement PF07678.14 KXL48599.1 - 0.02 14.0 0.0 0.12 11.4 0.0 2.2 1 1 1 2 2 2 0 A-macroglobulin TED domain Hydrolase_4 PF12146.8 KXL48600.1 - 5e-15 55.4 0.0 4.6e-09 35.9 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXL48600.1 - 6.9e-13 48.8 0.0 1.2e-08 34.9 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 KXL48600.1 - 7.3e-06 24.9 0.0 0.38 9.4 0.0 3.1 2 1 1 3 3 3 3 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 KXL48600.1 - 3.7e-05 23.3 0.0 0.14 11.6 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family FSH1 PF03959.13 KXL48600.1 - 0.00012 21.8 0.0 0.00017 21.3 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KXL48600.1 - 0.00015 22.5 0.0 0.00048 20.8 0.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 KXL48600.1 - 0.00016 21.3 0.0 0.0033 17.0 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 KXL48600.1 - 0.00033 20.6 0.0 0.0038 17.2 0.0 2.0 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF818 PF05677.12 KXL48600.1 - 0.0019 17.2 0.0 0.0026 16.8 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.16 KXL48600.1 - 0.0084 15.9 0.0 0.87 9.3 0.0 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KXL48600.1 - 0.039 13.8 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold LIDHydrolase PF10230.9 KXL48600.1 - 0.055 13.0 0.0 11 5.5 0.0 2.2 1 1 0 2 2 2 0 Lipid-droplet associated hydrolase Abhydrolase_5 PF12695.7 KXL48600.1 - 0.097 12.4 0.0 0.41 10.4 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family PPTA PF01239.22 KXL48601.1 - 9.8e-42 139.5 25.0 2.9e-10 39.5 0.5 6.6 7 0 0 7 7 7 5 Protein prenyltransferase alpha subunit repeat TPR_17 PF13431.6 KXL48601.1 - 0.021 15.2 2.7 1.6 9.3 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXL48601.1 - 0.094 13.2 1.1 17 6.0 0.0 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat PALP PF00291.25 KXL48602.1 - 1.7e-64 218.1 2.0 2e-64 217.8 2.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DAGK_cat PF00781.24 KXL48602.1 - 0.23 11.1 1.2 0.89 9.2 0.1 2.1 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain GHMP_kinases_N PF00288.26 KXL48603.1 - 4e-15 55.8 0.1 1.1e-14 54.4 0.1 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KXL48603.1 - 1.4e-09 38.1 0.0 8.1e-09 35.7 0.1 2.2 1 1 1 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 KXL48603.1 - 0.0082 15.7 0.1 0.017 14.6 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature M20_dimer PF07687.14 KXL48603.1 - 0.025 14.5 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 Peptidase dimerisation domain Ig_mannosidase PF17753.1 KXL48604.1 - 8.1e-26 89.6 0.5 1.7e-25 88.6 0.5 1.6 1 0 0 1 1 1 1 Ig-fold domain Mannosidase_ig PF17786.1 KXL48604.1 - 1.4e-14 54.4 0.1 5.7e-14 52.5 0.1 2.1 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KXL48604.1 - 6.2e-07 30.1 0.0 2.2e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 WIF PF02019.18 KXL48604.1 - 0.001 18.8 0.0 0.0033 17.1 0.0 1.8 2 0 0 2 2 2 1 WIF domain DUF4217 PF13959.6 KXL48604.1 - 0.17 12.1 0.0 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4217) AA_permease PF00324.21 KXL48605.1 - 1.8e-150 501.7 47.9 2e-150 501.5 47.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXL48605.1 - 4.6e-35 121.3 49.1 5.7e-35 121.0 49.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 KXL48605.1 - 0.06 12.2 2.4 0.11 11.2 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) Pkinase PF00069.25 KXL48607.1 - 1.5e-64 217.9 0.0 2.4e-64 217.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL48607.1 - 9.7e-41 139.8 0.0 1.4e-40 139.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXL48607.1 - 3.2e-09 36.5 0.0 9.9e-09 34.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KXL48607.1 - 2.3e-05 23.5 0.2 2.3e-05 23.5 0.2 2.0 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KXL48607.1 - 0.007 16.3 2.9 0.08 12.8 0.1 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KXL48607.1 - 0.035 13.5 0.2 0.1 11.9 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ferlin_C PF16165.5 KXL48607.1 - 0.058 13.3 0.4 0.12 12.3 0.4 1.5 1 0 0 1 1 1 0 Ferlin C-terminus RIO1 PF01163.22 KXL48607.1 - 0.29 10.7 0.0 0.29 10.7 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Glyco_transf_20 PF00982.21 KXL48608.1 - 4.6e-159 530.1 0.1 7.6e-159 529.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KXL48608.1 - 3.1e-37 128.0 0.0 4.9e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Cyclin PF08613.11 KXL48609.1 - 5e-41 140.8 0.5 2.2e-25 89.9 0.2 2.7 2 0 0 2 2 2 2 Cyclin Proteasome PF00227.26 KXL48611.1 - 2.2e-47 161.0 0.4 2.5e-47 160.8 0.4 1.0 1 0 0 1 1 1 1 Proteasome subunit SNF2_N PF00176.23 KXL48612.1 - 6.7e-63 212.5 0.0 1.1e-62 211.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 KXL48612.1 - 8.3e-07 28.8 12.5 2e-06 27.6 12.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXL48612.1 - 3.4e-06 26.8 13.7 7.7e-06 25.7 13.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXL48612.1 - 4e-06 26.6 13.7 8.7e-06 25.5 13.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXL48612.1 - 6.3e-06 26.4 15.6 1.4e-05 25.3 15.6 1.7 1 0 0 1 1 1 1 Ring finger domain Helicase_C PF00271.31 KXL48612.1 - 1.1e-05 25.8 0.0 7e-05 23.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Prok-RING_4 PF14447.6 KXL48612.1 - 2.2e-05 24.2 11.8 4.5e-05 23.2 11.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KXL48612.1 - 0.0017 18.3 9.8 0.002 18.1 8.1 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXL48612.1 - 0.0027 17.6 14.0 0.0055 16.6 14.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KXL48612.1 - 0.011 16.0 11.3 0.029 14.6 11.3 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain Surfac_D-trimer PF09006.11 KXL48612.1 - 0.024 14.5 0.6 0.18 11.7 0.0 2.8 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation TssO PF17561.2 KXL48612.1 - 0.13 12.4 0.3 2.1 8.4 0.0 2.5 2 0 0 2 2 2 0 Type VI secretion system, TssO zf-C3HC4_4 PF15227.6 KXL48612.1 - 1.3 9.2 12.9 3 8.1 12.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Di19 PF05605.12 KXL48612.1 - 3.6 7.9 6.7 24 5.3 2.0 3.0 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Fe-ADH PF00465.19 KXL48613.1 - 1.1e-06 27.8 0.0 1.3e-06 27.5 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase M20_dimer PF07687.14 KXL48615.1 - 5.3e-20 71.4 0.1 9.2e-20 70.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KXL48615.1 - 1.2e-17 64.4 0.3 2.1e-13 50.5 0.2 2.2 2 0 0 2 2 2 2 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 KXL48615.1 - 0.0046 16.7 0.7 0.011 15.5 0.0 1.9 3 0 0 3 3 3 1 Peptidase family M28 Pkinase PF00069.25 KXL48616.1 - 2.2e-69 233.8 0.0 3.6e-69 233.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL48616.1 - 4.8e-49 167.0 0.0 1.4e-48 165.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXL48616.1 - 0.00037 19.4 0.0 0.00074 18.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXL48616.1 - 0.00083 18.7 0.0 0.01 15.2 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Fungal_trans_2 PF11951.8 KXL48617.1 - 1.9e-15 56.5 0.8 3.5e-15 55.7 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL48617.1 - 9.6e-07 28.8 9.9 1.9e-06 27.9 9.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ecm29 PF13001.7 KXL48619.1 - 2.6e-151 504.7 0.1 4.2e-150 500.7 0.0 3.0 4 0 0 4 4 4 1 Proteasome stabiliser Vac14_Fab1_bd PF12755.7 KXL48619.1 - 4.4e-06 27.2 1.6 0.00033 21.2 0.1 4.3 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KXL48619.1 - 0.00048 20.1 0.2 3.7 8.1 0.0 6.2 6 0 0 6 6 6 1 HEAT repeat MMS19_C PF12460.8 KXL48619.1 - 0.29 10.2 4.8 1.4 8.0 0.4 3.3 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal EXS PF03124.14 KXL48620.1 - 6e-90 301.9 12.8 6.9e-90 301.7 12.8 1.0 1 0 0 1 1 1 1 EXS family Pro-kuma_activ PF09286.11 KXL48621.1 - 8e-34 117.0 0.2 2.7e-33 115.3 0.1 1.9 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KXL48621.1 - 9.8e-06 25.0 0.4 1.6e-05 24.4 0.4 1.2 1 0 0 1 1 1 1 Subtilase family PEPCK_ATP PF01293.20 KXL48622.1 - 0.2 10.3 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase YrhK PF14145.6 KXL48622.1 - 2.1 8.3 33.5 0.35 10.8 3.4 5.1 3 2 0 4 4 4 0 YrhK-like protein Mitoc_mL59 PF18126.1 KXL48623.1 - 1.2e-45 154.9 2.5 1.7e-45 154.5 2.5 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 Proteasome PF00227.26 KXL48624.1 - 8.3e-41 139.6 0.0 1e-40 139.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit RSN1_7TM PF02714.15 KXL48625.1 - 2e-79 266.7 24.1 4.8e-79 265.5 24.1 1.7 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KXL48625.1 - 9.4e-38 129.4 1.0 9.4e-38 129.4 1.0 3.0 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KXL48625.1 - 1.3e-35 123.2 0.0 2e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RRM_1 PF00076.22 KXL48625.1 - 0.04 13.7 0.4 4.3 7.2 0.0 3.1 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3431 PF11913.8 KXL48626.1 - 3.9e-69 232.7 0.1 4.9e-69 232.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) AAA PF00004.29 KXL48627.1 - 1.1e-29 103.5 0.0 2.4e-29 102.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXL48627.1 - 3.3e-06 27.6 0.0 9.3e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXL48627.1 - 1.4e-05 25.4 0.3 9.4e-05 22.7 0.1 2.4 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.6 KXL48627.1 - 1.5e-05 25.5 0.0 3.6e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXL48627.1 - 8.2e-05 22.8 0.0 0.00021 21.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KXL48627.1 - 0.00016 22.1 0.0 0.00033 21.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KXL48627.1 - 0.00017 21.4 0.0 0.00034 20.4 0.0 1.4 1 0 0 1 1 1 1 Cytidylate kinase RNA_helicase PF00910.22 KXL48627.1 - 0.00021 21.6 0.0 0.00048 20.5 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.6 KXL48627.1 - 0.00065 19.3 0.2 0.16 11.5 0.0 2.3 1 1 1 2 2 2 1 AAA domain NACHT PF05729.12 KXL48627.1 - 0.00078 19.4 0.1 0.0057 16.6 0.0 2.4 1 1 1 2 2 2 1 NACHT domain Viral_helicase1 PF01443.18 KXL48627.1 - 0.0056 16.4 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 KXL48627.1 - 0.006 16.6 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 KXL48627.1 - 0.0064 16.4 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain ABC_tran PF00005.27 KXL48627.1 - 0.01 16.3 0.0 0.026 15.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KXL48627.1 - 0.011 15.5 0.0 0.028 14.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 KXL48627.1 - 0.011 16.0 0.0 0.035 14.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 KXL48627.1 - 0.015 15.3 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 KXL48627.1 - 0.017 14.5 0.0 0.14 11.5 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 KXL48627.1 - 0.02 14.7 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KXL48627.1 - 0.023 14.7 0.0 0.064 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KXL48627.1 - 0.026 14.2 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain SKI PF01202.22 KXL48627.1 - 0.028 14.6 0.0 0.052 13.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase RuvB_N PF05496.12 KXL48627.1 - 0.029 14.1 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ATP_bind_1 PF03029.17 KXL48627.1 - 0.031 14.0 0.0 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 KXL48627.1 - 0.059 13.5 0.1 0.28 11.3 0.0 2.2 2 1 0 2 2 1 0 50S ribosome-binding GTPase ATPase_2 PF01637.18 KXL48627.1 - 0.067 13.1 0.0 4.5 7.1 0.0 2.2 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KXL48627.1 - 0.069 12.9 0.1 0.29 10.9 0.0 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein KTI12 PF08433.10 KXL48627.1 - 0.09 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_24 PF13479.6 KXL48627.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 KXL48627.1 - 0.12 12.5 0.0 0.39 10.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain (Cdc48 subfamily) CPT PF07931.12 KXL48627.1 - 0.13 12.1 0.0 0.34 10.7 0.0 1.8 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein RsgA_GTPase PF03193.16 KXL48627.1 - 0.14 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Cytidylate_kin2 PF13189.6 KXL48627.1 - 0.14 12.2 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase-like family ADK PF00406.22 KXL48627.1 - 0.15 12.2 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Adenylate kinase NTPase_1 PF03266.15 KXL48627.1 - 0.17 11.8 0.1 0.42 10.5 0.0 1.6 2 0 0 2 2 1 0 NTPase AAA_23 PF13476.6 KXL48627.1 - 0.18 12.3 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KXL48627.1 - 0.19 10.8 0.1 0.56 9.3 0.0 1.8 3 0 0 3 3 1 0 Protein of unknown function (DUF815) AAA_13 PF13166.6 KXL48627.1 - 0.29 9.7 0.1 0.44 9.1 0.1 1.2 1 0 0 1 1 1 0 AAA domain Myb_DNA-bind_6 PF13921.6 KXL48628.1 - 3.5e-10 40.0 3.7 3.5e-10 40.0 3.7 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain HSA PF07529.13 KXL48628.1 - 8.8e-08 32.4 4.3 8.8e-08 32.4 4.3 3.9 4 0 0 4 4 4 1 HSA Myb_DNA-binding PF00249.31 KXL48628.1 - 0.012 15.7 1.6 0.037 14.2 1.6 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain WD40 PF00400.32 KXL48629.1 - 3.8e-11 43.4 0.0 0.91 10.5 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL48629.1 - 3.7e-06 27.1 0.0 0.56 10.5 0.0 5.1 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain HrcA PF01628.21 KXL48629.1 - 0.0039 17.1 0.0 3.4 7.5 0.0 2.2 2 0 0 2 2 2 2 HrcA protein C terminal domain CRT10 PF08728.10 KXL48629.1 - 0.038 12.2 0.0 0.072 11.3 0.0 1.3 1 0 0 1 1 1 0 CRT10 DMRL_synthase PF00885.19 KXL48630.1 - 1.6e-54 183.5 0.0 2.1e-54 183.2 0.0 1.2 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase GalBD_like PF17974.1 KXL48630.1 - 0.017 15.3 0.0 0.021 15.0 0.0 1.2 1 0 0 1 1 1 0 Galactose-binding domain-like N-SET PF11764.8 KXL48631.1 - 1.3e-58 198.0 1.2 1.3e-58 198.0 1.2 2.9 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 KXL48631.1 - 2.6e-27 94.2 0.3 6.5e-27 93.0 0.0 1.9 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated SET PF00856.28 KXL48631.1 - 2.8e-21 76.7 0.2 2.8e-21 76.7 0.2 3.4 2 2 0 2 2 2 1 SET domain RRM_1 PF00076.22 KXL48631.1 - 0.00013 21.7 0.0 0.00031 20.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SWIB PF02201.18 KXL48632.1 - 5.2e-28 96.7 0.0 9.3e-28 95.9 0.0 1.3 1 0 0 1 1 1 1 SWIB/MDM2 domain SRP-alpha_N PF04086.13 KXL48632.1 - 0.0013 18.7 18.8 0.0014 18.6 18.8 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal Macoilin PF09726.9 KXL48632.1 - 0.11 11.0 10.5 0.12 10.9 10.5 1.0 1 0 0 1 1 1 0 Macoilin family FAM176 PF14851.6 KXL48632.1 - 6.7 6.4 6.2 5.6 6.6 0.1 2.3 2 0 0 2 2 2 0 FAM176 family DEK_C PF08766.11 KXL48633.1 - 6.6e-11 42.0 0.0 7.6e-11 41.8 0.0 1.0 1 0 0 1 1 1 1 DEK C terminal domain eIF2A PF08662.11 KXL48634.1 - 2.8e-39 135.0 1.9 8.7e-36 123.6 0.1 4.1 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 KXL48634.1 - 1.1e-05 25.1 0.0 2.6e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 KXL48634.1 - 0.0024 18.6 0.5 2.7 9.0 0.0 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat MPC PF03650.13 KXL48635.1 - 3.5e-37 126.9 0.0 5e-37 126.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers CAP PF00188.26 KXL48636.1 - 2.5e-20 73.6 8.3 9.3e-20 71.7 8.3 1.7 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Ribosomal_L5_C PF00673.21 KXL48637.1 - 2.3e-22 79.0 0.0 3.4e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KXL48637.1 - 2.5e-20 72.6 0.0 7.5e-20 71.0 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.22 KXL48638.1 - 9.1e-18 63.7 0.1 1.2e-17 63.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain Sod_Fe_C PF02777.18 KXL48640.1 - 4.1e-16 59.0 0.2 1.9e-07 31.2 0.1 2.6 2 1 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain CFEM PF05730.11 KXL48641.1 - 4.4e-11 42.7 14.2 4.4e-11 42.7 14.2 1.9 2 0 0 2 2 2 1 CFEM domain Senescence_reg PF04520.13 KXL48641.1 - 0.041 14.7 6.3 0.057 14.2 6.3 1.2 1 0 0 1 1 1 0 Senescence regulator Miga PF10265.9 KXL48641.1 - 3.2 6.6 8.3 4 6.3 8.3 1.1 1 0 0 1 1 1 0 Mitoguardin VEGFR-2_TMD PF17988.1 KXL48642.1 - 0.61 9.6 3.6 1.2 8.6 3.6 1.4 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain G_glu_transpept PF01019.21 KXL48643.1 - 1e-170 568.9 0.1 1.2e-170 568.7 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase CHCH PF06747.13 KXL48644.1 - 2.8e-07 30.5 2.1 7.8e-07 29.1 1.8 1.8 1 1 1 2 2 2 1 CHCH domain MTCP1 PF08991.10 KXL48644.1 - 0.0029 17.8 1.3 0.0042 17.3 1.3 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Pet191_N PF10203.9 KXL48644.1 - 0.038 14.3 3.4 0.07 13.4 3.4 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 SHR3_chaperone PF08229.11 KXL48645.1 - 1.8e-74 248.8 0.0 2.3e-74 248.5 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 Methyltransf_16 PF10294.9 KXL48647.1 - 2.5e-39 134.8 0.0 4e-39 134.1 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 KXL48647.1 - 0.00013 21.8 0.0 0.00021 21.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXL48647.1 - 0.00049 19.7 0.0 0.0013 18.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KXL48647.1 - 0.0018 19.0 0.0 0.0032 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL48647.1 - 0.002 18.9 0.0 0.0033 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KXL48647.1 - 0.16 11.2 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_4 PF02390.17 KXL48647.1 - 0.24 10.8 0.0 0.43 10.0 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase NatB_MDM20 PF09797.9 KXL48648.1 - 9.5e-25 87.3 0.0 1.8e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit DUF4042 PF13251.6 KXL48648.1 - 0.059 13.1 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4042) DnaJ PF00226.31 KXL48649.1 - 1e-10 41.5 0.2 6.9e-10 38.9 0.1 2.2 2 0 0 2 2 2 1 DnaJ domain PRA1 PF03208.19 KXL48650.1 - 4.4e-38 130.1 3.2 5.4e-38 129.8 3.2 1.1 1 0 0 1 1 1 1 PRA1 family protein DUF2207 PF09972.9 KXL48650.1 - 0.095 11.4 1.0 0.1 11.3 1.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) NPR3 PF03666.13 KXL48650.1 - 0.18 10.5 0.7 0.22 10.3 0.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Renin_r PF07850.14 KXL48650.1 - 0.54 10.9 2.4 1.2 9.8 2.4 1.6 1 1 0 1 1 1 0 Renin receptor-like protein Macoilin PF09726.9 KXL48651.1 - 1 7.8 7.5 1.3 7.5 7.5 1.1 1 0 0 1 1 1 0 Macoilin family NMO PF03060.15 KXL48652.1 - 2.8e-53 181.5 0.4 4.1e-53 180.9 0.4 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KXL48652.1 - 1.1e-07 31.2 0.7 2.7e-07 29.9 0.7 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KXL48652.1 - 0.0013 17.8 3.2 0.0026 16.8 3.2 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase RFX_DNA_binding PF02257.15 KXL48653.1 - 0.052 14.2 0.2 0.065 13.9 0.2 1.2 1 0 0 1 1 1 0 RFX DNA-binding domain p450 PF00067.22 KXL48655.1 - 6.5e-63 213.1 0.0 8e-63 212.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mannosyl_trans4 PF15971.5 KXL48655.1 - 0.14 12.0 2.7 0.23 11.3 2.7 1.3 1 0 0 1 1 1 0 DolP-mannose mannosyltransferase Fungal_trans PF04082.18 KXL48657.1 - 0.00068 18.7 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DJ-1_PfpI PF01965.24 KXL48659.1 - 1.8e-16 60.4 0.0 3.4e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KXL48659.1 - 2.6e-06 27.3 0.0 3.6e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like MOFRL PF05161.13 KXL48659.1 - 0.032 14.4 0.2 0.086 13.0 0.2 1.7 1 0 0 1 1 1 0 MOFRL family SNO PF01174.19 KXL48659.1 - 0.078 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Cut12 PF11500.8 KXL48660.1 - 0.0012 18.8 1.0 0.0014 18.6 1.0 1.1 1 0 0 1 1 1 1 Spindle pole body formation-associated protein Fungal_trans PF04082.18 KXL48661.1 - 6.5e-12 45.0 0.0 1.2e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KXL48662.1 - 3.6e-13 49.2 8.1 4.7e-06 26.8 0.2 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXL48662.1 - 7.2e-12 45.2 11.1 1.3e-10 41.2 1.4 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXL48662.1 - 5.6e-09 36.1 7.4 0.00039 21.0 2.0 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXL48662.1 - 0.0039 17.2 5.2 0.74 9.9 0.1 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 KXL48662.1 - 0.006 16.9 1.7 0.0067 16.7 1.7 1.1 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Baculo_IE-1 PF05290.11 KXL48662.1 - 0.016 15.2 0.5 0.16 11.9 0.5 1.9 1 1 1 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-C2H2_11 PF16622.5 KXL48662.1 - 0.016 14.9 5.5 0.43 10.4 0.1 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type Zf_RING PF16744.5 KXL48662.1 - 0.018 15.1 2.8 0.04 14.0 0.3 2.0 1 1 1 2 2 2 0 KIAA1045 RING finger BolA PF01722.18 KXL48662.1 - 0.029 14.7 0.1 0.035 14.4 0.1 1.2 1 0 0 1 1 1 0 BolA-like protein zf-MYST PF17772.1 KXL48662.1 - 0.054 13.1 2.3 1.9 8.1 0.1 2.0 1 1 1 2 2 2 0 MYST family zinc finger domain Spt46 PF17734.1 KXL48662.1 - 0.084 12.7 3.4 0.35 10.6 3.4 1.7 1 1 1 2 2 2 0 Spermatogenesis-associated protein 46 zf-C2HE PF16278.5 KXL48662.1 - 0.11 13.0 3.0 3.1 8.3 0.2 2.0 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 KXL48662.1 - 0.13 12.7 4.3 0.31 11.5 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 KXL48662.1 - 0.16 11.6 3.7 1.5 8.5 3.3 2.0 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Pro-kuma_activ PF09286.11 KXL48664.1 - 9.2e-38 129.7 0.0 2.3e-37 128.5 0.0 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KXL48664.1 - 0.00019 20.8 0.2 0.00028 20.2 0.2 1.2 1 0 0 1 1 1 1 Subtilase family Glyco_hydro_10 PF00331.20 KXL48666.1 - 4.1e-80 269.3 0.3 4.7e-80 269.1 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Tim17 PF02466.19 KXL48667.1 - 2.7e-38 130.8 7.6 3.6e-38 130.4 7.6 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.12 KXL48667.1 - 0.074 13.0 1.1 0.22 11.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF543) DUF4048 PF13257.6 KXL48668.1 - 4.2e-44 151.3 20.4 4.2e-44 151.3 20.4 3.4 4 0 0 4 4 4 1 Domain of unknown function (DUF4048) Unstab_antitox PF09720.10 KXL48668.1 - 0.0073 16.3 0.1 0.027 14.5 0.1 2.0 2 0 0 2 2 2 1 Putative addiction module component Bap31_Bap29_C PF18035.1 KXL48668.1 - 0.0085 16.1 2.9 0.018 15.0 2.9 1.5 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain GAS PF13851.6 KXL48668.1 - 0.033 13.5 1.4 0.06 12.7 1.4 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Peptidase_M18 PF02127.15 KXL48669.1 - 6.1e-130 433.9 0.0 8.1e-130 433.5 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Yos9_DD PF17880.1 KXL48670.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 Yos9 dimerzation domain Syntaxin-6_N PF09177.11 KXL48671.1 - 3.9e-20 72.3 4.8 6.1e-20 71.6 1.2 2.2 2 0 0 2 2 2 1 Syntaxin 6, N-terminal STAT_alpha PF01017.20 KXL48671.1 - 0.023 14.6 2.8 1.6 8.6 0.0 2.9 2 1 1 3 3 3 0 STAT protein, all-alpha domain SNARE PF05739.19 KXL48671.1 - 0.052 13.6 0.4 0.14 12.2 0.4 1.8 1 0 0 1 1 1 0 SNARE domain ArAE_2_N PF10337.9 KXL48671.1 - 0.094 11.7 0.7 0.16 11.0 0.7 1.5 1 1 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Prominin PF05478.11 KXL48671.1 - 0.16 9.9 0.9 0.43 8.5 0.1 1.8 2 0 0 2 2 2 0 Prominin DUF1664 PF07889.12 KXL48671.1 - 0.19 11.8 2.7 7 6.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) HisKA_3 PF07730.13 KXL48671.1 - 0.3 11.6 0.1 0.3 11.6 0.1 3.0 3 1 0 3 3 3 0 Histidine kinase Methyltransf_32 PF13679.6 KXL48672.1 - 3.8e-26 92.0 0.0 7.3e-26 91.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXL48673.1 - 3e-14 53.2 0.0 5.4e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL48673.1 - 3.7e-14 52.8 0.0 1e-13 51.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL48673.1 - 2.3e-12 47.4 0.0 6.8e-12 45.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL48673.1 - 3.6e-10 40.4 0.0 7.1e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL48673.1 - 7.9e-09 36.2 0.0 1.9e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KXL48673.1 - 2.1e-07 31.2 0.0 3e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 KXL48673.1 - 4.1e-06 26.4 0.0 7.2e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KXL48673.1 - 5.4e-05 22.7 0.0 0.00011 21.7 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 KXL48673.1 - 0.0081 15.6 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 KXL48673.1 - 0.0089 16.0 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KXL48673.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PCMT PF01135.19 KXL48673.1 - 0.013 15.2 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 KXL48673.1 - 0.015 14.6 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TehB PF03848.14 KXL48673.1 - 0.03 13.7 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB CMAS PF02353.20 KXL48673.1 - 0.04 13.2 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_17 PF12692.7 KXL48673.1 - 0.042 13.9 0.0 0.089 12.8 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase Methyltransf_2 PF00891.18 KXL48673.1 - 0.098 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain TPMT PF05724.11 KXL48673.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.7 KXL48673.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF3405 PF11885.8 KXL48674.1 - 1.7e-181 604.4 13.8 2e-181 604.1 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) HET PF06985.11 KXL48675.1 - 1.6e-15 57.7 0.2 3.5e-15 56.6 0.1 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) IBR PF01485.21 KXL48676.1 - 7.7e-07 29.2 4.8 7.7e-07 29.2 4.8 3.3 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain Adipokin_hormo PF06377.11 KXL48676.1 - 0.019 15.3 0.0 0.037 14.4 0.0 1.8 1 1 0 1 1 1 0 Adipokinetic hormone ACT_7 PF13840.6 KXL48677.1 - 3.8e-23 81.0 0.0 6.3e-15 54.7 0.0 2.6 3 0 0 3 3 3 2 ACT domain CDH-cyt PF16010.5 KXL48679.1 - 2.4e-55 187.1 3.4 3.9e-55 186.4 3.4 1.4 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 KXL48679.1 - 8.7e-27 94.3 0.0 2.1e-26 93.0 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXL48679.1 - 1.3e-24 87.3 0.1 2.7e-24 86.3 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXL48679.1 - 6.1e-07 28.9 0.1 0.0019 17.4 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXL48679.1 - 6e-05 23.2 0.0 0.0002 21.5 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXL48679.1 - 0.00019 21.1 1.5 0.0042 16.7 1.5 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase DOMON PF03351.17 KXL48679.1 - 0.00041 20.5 0.1 0.0012 19.0 0.1 1.7 1 0 0 1 1 1 1 DOMON domain Thi4 PF01946.17 KXL48679.1 - 0.00099 18.4 0.1 0.093 12.0 0.1 2.3 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KXL48679.1 - 0.0019 17.5 0.1 0.006 15.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXL48679.1 - 0.0072 15.1 0.0 0.017 13.8 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KXL48679.1 - 0.009 16.6 0.0 13 6.4 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXL48679.1 - 0.015 14.6 0.4 0.12 11.6 0.4 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXL48679.1 - 0.017 14.2 0.1 0.026 13.6 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein IPP-2 PF04979.14 KXL48680.1 - 4.3e-21 76.0 16.8 1.3e-20 74.4 16.8 1.8 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) DUF3410 PF11890.8 KXL48680.1 - 0.11 12.3 0.7 0.77 9.6 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3410) SBP_bac_3 PF00497.20 KXL48681.1 - 0.026 14.0 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.11 KXL48681.1 - 0.027 14.4 0.0 0.093 12.7 0.0 1.9 2 0 0 2 2 2 0 NMT1/THI5 like Rrp15p PF07890.12 KXL48682.1 - 1.1e-38 132.6 5.7 1.1e-38 132.6 5.7 2.4 2 1 0 2 2 2 1 Rrp15p BSP_II PF05432.11 KXL48682.1 - 0.12 12.1 8.9 0.18 11.5 8.9 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Macoilin PF09726.9 KXL48682.1 - 9.2 4.7 13.9 10 4.5 13.9 1.2 1 0 0 1 1 1 0 Macoilin family SRP54 PF00448.22 KXL48683.1 - 2.9e-74 249.0 0.9 5.5e-74 248.1 0.6 1.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KXL48683.1 - 1.8e-31 108.7 5.2 1.8e-31 108.7 5.2 3.7 3 1 1 4 4 4 1 Signal peptide binding domain SRP54_N PF02881.19 KXL48683.1 - 2.7e-17 62.8 0.3 6.6e-17 61.5 0.3 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 KXL48683.1 - 1.1e-05 25.1 1.1 6.8e-05 22.5 0.5 2.4 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 KXL48683.1 - 0.00016 21.9 0.0 0.00071 19.9 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXL48683.1 - 0.00019 21.6 0.1 0.00042 20.5 0.1 1.6 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 KXL48683.1 - 0.00023 20.3 0.5 0.0031 16.6 0.5 2.3 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KXL48683.1 - 0.00058 20.3 0.0 0.0014 19.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.6 KXL48683.1 - 0.00089 19.7 0.2 0.0037 17.7 0.0 2.2 2 0 0 2 2 1 1 AAA domain CbiA PF01656.23 KXL48683.1 - 0.0028 17.7 0.0 0.0072 16.4 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 KXL48683.1 - 0.0031 17.3 0.2 0.0031 17.3 0.2 2.2 3 0 0 3 3 2 1 AAA domain APS_kinase PF01583.20 KXL48683.1 - 0.0058 16.5 0.4 0.017 15.0 0.0 1.9 2 0 0 2 2 2 1 Adenylylsulphate kinase MobB PF03205.14 KXL48683.1 - 0.0059 16.5 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Thymidylate_kin PF02223.17 KXL48683.1 - 0.016 14.9 0.3 0.066 12.9 0.0 2.0 2 0 0 2 2 2 0 Thymidylate kinase 6PF2K PF01591.18 KXL48683.1 - 0.019 14.3 0.0 0.041 13.2 0.0 1.5 1 0 0 1 1 1 0 6-phosphofructo-2-kinase ATP_bind_1 PF03029.17 KXL48683.1 - 0.03 14.1 0.2 0.16 11.8 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 KXL48683.1 - 0.036 14.6 0.0 0.093 13.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KXL48683.1 - 0.042 14.1 0.0 0.091 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 KXL48683.1 - 0.044 13.2 0.7 5.7 6.3 0.0 3.5 4 0 0 4 4 4 0 Signal recognition particle receptor beta subunit AAA PF00004.29 KXL48683.1 - 0.059 13.8 0.1 0.3 11.5 0.0 2.4 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KXL48683.1 - 0.074 13.1 0.0 0.4 10.8 0.0 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 KXL48683.1 - 0.11 12.2 0.2 0.56 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain VirC1 PF07015.11 KXL48683.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 VirC1 protein HTH_ParB PF17762.1 KXL48683.1 - 0.15 11.9 1.1 8.8 6.2 0.0 2.9 2 1 0 2 2 2 0 HTH domain found in ParB protein ResIII PF04851.15 KXL48683.1 - 0.16 12.0 0.3 0.56 10.2 0.3 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit MFS_1 PF07690.16 KXL48684.1 - 5.8e-12 45.2 12.5 5.8e-12 45.2 12.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL48684.1 - 7.8e-08 31.6 3.0 2e-07 30.2 1.1 2.3 1 1 1 2 2 2 1 Sugar (and other) transporter DUF4212 PF13937.6 KXL48684.1 - 3.2 8.2 9.1 0.35 11.3 0.9 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) Fungal_trans PF04082.18 KXL48685.1 - 2.6e-19 69.3 1.5 4.6e-19 68.5 1.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL48685.1 - 2.8e-06 27.3 13.5 8e-06 25.9 13.5 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MIP PF00230.20 KXL48686.1 - 3.5e-26 92.3 0.0 4e-26 92.1 0.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein Sugar_tr PF00083.24 KXL48687.1 - 4.2e-64 217.1 20.3 4.4e-36 124.7 9.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXL48687.1 - 3.8e-21 75.4 33.4 5.3e-17 61.8 14.1 2.2 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXL48687.1 - 0.00015 20.3 0.7 0.00015 20.3 0.7 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) T3SS_needle_reg PF09025.10 KXL48687.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 YopR, type III needle-polymerisation regulator NDUF_B12 PF08122.12 KXL48687.1 - 2.5 8.2 7.0 15 5.7 0.1 3.5 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family Ion_trans_2 PF07885.16 KXL48688.1 - 4.4e-29 100.3 23.7 1.8e-15 56.6 4.8 3.0 3 0 0 3 3 3 2 Ion channel Lig_chan PF00060.26 KXL48688.1 - 0.0017 18.2 2.1 0.0068 16.2 2.1 2.0 1 0 0 1 1 1 1 Ligand-gated ion channel Ion_trans PF00520.31 KXL48688.1 - 0.14 11.4 19.9 1.7 7.8 5.6 2.8 2 1 1 3 3 3 0 Ion transport protein TRAP-gamma PF07074.12 KXL48688.1 - 0.18 11.4 0.0 0.47 10.0 0.0 1.7 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF2101 PF09874.9 KXL48688.1 - 1.7 8.3 3.6 1.1 8.9 0.1 2.2 3 0 0 3 3 3 0 Predicted membrane protein (DUF2101) Trp_oprn_chp PF09534.10 KXL48688.1 - 1.8 8.4 5.3 0.22 11.3 0.2 2.1 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Ni_hydr_CYTB PF01292.20 KXL48688.1 - 5.3 6.6 10.4 2.7 7.5 4.6 2.5 2 1 0 2 2 2 0 Prokaryotic cytochrome b561 MSA-2c PF12238.8 KXL48689.1 - 0.031 14.3 0.1 0.038 14.0 0.1 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c ATP-synt_D PF01813.17 KXL48689.1 - 0.041 13.7 0.0 0.4 10.5 0.0 2.0 2 0 0 2 2 2 0 ATP synthase subunit D DUF4398 PF14346.6 KXL48689.1 - 6 7.6 7.9 7.2 7.3 1.8 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4398) DUF4519 PF15012.6 KXL48690.1 - 3 8.1 4.8 0.96 9.7 2.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Ribosomal_L37e PF01907.19 KXL48693.1 - 2.5e-27 94.8 10.1 3.9e-27 94.2 10.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 KXL48693.1 - 0.0088 16.0 0.9 0.013 15.5 0.9 1.2 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 KXL48693.1 - 0.022 14.8 0.4 0.028 14.4 0.4 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_2 PF13240.6 KXL48693.1 - 0.04 13.7 1.5 4.8 7.0 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KXL48693.1 - 0.16 11.4 1.8 0.31 10.5 1.8 1.5 1 1 0 1 1 1 0 zinc-ribbon domain Rubredoxin_2 PF18073.1 KXL48693.1 - 0.16 11.7 2.6 2.7 7.8 0.2 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-C3HC4_2 PF13923.6 KXL48693.1 - 0.2 11.5 3.1 0.34 10.8 3.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_6 PF14599.6 KXL48693.1 - 0.43 10.6 3.1 0.73 9.9 3.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon adh_short PF00106.25 KXL48694.1 - 1.4e-11 44.2 0.0 1.8e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL48694.1 - 1e-08 35.3 0.0 1.7e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KXL48694.1 - 3.4e-07 30.1 0.0 4e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 KXL48694.1 - 0.046 12.8 0.0 0.06 12.5 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TrkA_N PF02254.18 KXL48694.1 - 0.15 12.4 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Cupin_2 PF07883.11 KXL48695.1 - 4.1e-08 32.8 0.0 7.4e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KXL48695.1 - 0.028 14.1 0.0 0.063 13.0 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF861) Glyco_hydro_12 PF01670.16 KXL48697.1 - 4.5e-18 66.0 5.6 5.6e-18 65.7 5.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 BPL_LplA_LipB PF03099.19 KXL48698.1 - 1.9e-07 31.0 0.0 2.9e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Rpp20 PF12328.8 KXL48699.1 - 1.6e-27 96.1 6.7 1.5e-26 93.0 6.7 2.3 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 KXL48699.1 - 1.3e-08 34.5 0.0 7.8e-08 32.0 0.0 2.0 1 1 0 1 1 1 1 Alba CRIM PF16978.5 KXL48700.1 - 7.1e-32 110.5 0.0 1.2e-31 109.8 0.0 1.4 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 KXL48700.1 - 3.2e-17 62.8 0.0 5.8e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology PX PF00787.24 KXL48701.1 - 2.9e-24 85.2 0.0 3.6e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 PX domain 2-Hacid_dh_C PF02826.19 KXL48702.1 - 1e-52 178.1 0.0 1.3e-52 177.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXL48702.1 - 9e-18 64.2 0.0 1.1e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXL48702.1 - 3.6e-07 30.5 0.3 8.2e-07 29.3 0.1 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KXL48702.1 - 0.015 15.9 0.0 0.03 14.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 KXL48702.1 - 0.1 13.4 0.0 0.53 11.1 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold TRI12 PF06609.13 KXL48703.1 - 6.5e-29 100.8 29.9 7.3e-29 100.6 29.9 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KXL48703.1 - 3.9e-23 82.0 50.8 3.9e-23 82.0 50.8 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL48703.1 - 1.2e-08 34.2 9.1 1.2e-08 34.2 9.1 3.1 2 1 0 3 3 3 1 Sugar (and other) transporter Bee_toxin PF17454.2 KXL48703.1 - 0.23 11.5 1.5 25 5.0 0.4 2.7 2 0 0 2 2 2 0 Honey bee toxin TPR_2 PF07719.17 KXL48704.1 - 7.8e-05 22.5 18.2 0.096 12.9 0.1 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXL48704.1 - 0.00082 19.4 6.6 0.26 11.6 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXL48704.1 - 0.0011 18.7 15.3 0.0043 16.8 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXL48704.1 - 0.025 14.2 9.1 3.3 7.5 0.0 5.1 6 0 0 6 6 6 0 TPR repeat TPR_7 PF13176.6 KXL48704.1 - 0.054 13.5 3.6 10 6.4 0.0 4.7 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXL48704.1 - 0.46 11.4 9.2 4.1 8.5 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXL48704.1 - 0.57 10.7 12.1 1.9 9.1 0.2 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXL48704.1 - 7.1 7.0 13.6 2.4 8.5 0.1 5.3 7 0 0 7 7 7 0 Tetratricopeptide repeat Aldedh PF00171.22 KXL48705.1 - 9.9e-143 476.0 0.0 1.2e-142 475.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KXL48705.1 - 0.21 11.0 0.0 1 8.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Abhydrolase_1 PF00561.20 KXL48706.1 - 1.1e-13 51.5 0.0 9.3e-13 48.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXL48706.1 - 1.6e-08 35.5 0.4 2.2e-08 35.0 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXL48706.1 - 0.00048 19.5 0.0 0.01 15.1 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KXL48706.1 - 0.0023 17.4 0.0 0.094 12.2 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KXL48706.1 - 0.085 12.7 0.2 1.5 8.6 0.1 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold DUF1057 PF06342.12 KXL48706.1 - 0.089 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) EpuA PF11772.8 KXL48706.1 - 0.11 12.2 0.3 0.29 10.8 0.3 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta DUF3176 PF11374.8 KXL48707.1 - 3.7e-30 104.3 1.7 3.7e-30 104.3 1.7 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF3176) LSPR PF06049.12 KXL48708.1 - 0.29 11.1 1.1 59 4.1 0.0 3.6 3 0 0 3 3 3 0 Coagulation Factor V LSPD Repeat Dsh_C PF12316.8 KXL48709.1 - 1.5 9.1 12.8 1 9.7 11.2 1.5 1 1 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal GEN1_C PF18380.1 KXL48710.1 - 1.1e-27 96.9 0.1 4.6e-27 95.0 0.0 2.1 2 0 0 2 2 2 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I PF00867.18 KXL48710.1 - 2e-25 89.0 0.0 4.5e-25 87.8 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KXL48710.1 - 3.3e-08 33.9 0.0 7.9e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 KXL48710.1 - 0.027 14.0 0.0 0.069 12.6 0.0 1.6 1 0 0 1 1 1 0 XPG domain containing Uds1 PF15456.6 KXL48711.1 - 2e-35 121.8 7.1 2e-35 121.8 7.1 5.3 4 2 1 5 5 5 1 Up-regulated During Septation HR1 PF02185.16 KXL48711.1 - 7.8e-06 25.9 0.5 7.8e-06 25.9 0.5 8.1 6 2 1 7 7 7 2 Hr1 repeat DUF3450 PF11932.8 KXL48711.1 - 0.0032 16.8 6.2 0.0032 16.8 6.2 6.9 6 2 2 9 9 9 1 Protein of unknown function (DUF3450) Tropomyosin_1 PF12718.7 KXL48711.1 - 0.012 15.8 2.1 0.012 15.8 2.1 6.8 6 1 1 7 7 7 0 Tropomyosin like PBECR1 PF18809.1 KXL48711.1 - 0.83 10.3 0.0 0.83 10.3 0.0 3.2 4 0 0 4 4 4 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease1 Fez1 PF06818.15 KXL48711.1 - 8 6.9 66.5 0.58 10.6 20.2 5.1 2 2 2 5 5 5 0 Fez1 Aminotran_1_2 PF00155.21 KXL48712.1 - 2.3e-47 161.9 0.0 2.8e-47 161.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II MWFE PF15879.5 KXL48713.1 - 4.1e-32 110.1 0.7 6.1e-32 109.6 0.7 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit MOZ_SAS PF01853.18 KXL48714.1 - 5.7e-67 224.8 0.0 6.5e-33 113.9 0.0 2.2 2 0 0 2 2 2 2 MOZ/SAS family zf-MYST PF17772.1 KXL48714.1 - 2.2e-19 68.8 5.7 5.2e-19 67.6 5.7 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain PHD_4 PF16866.5 KXL48714.1 - 5.7e-11 42.3 6.8 5.7e-11 42.3 6.8 2.1 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 KXL48714.1 - 0.00033 20.5 8.0 0.00033 20.5 8.0 2.3 2 0 0 2 2 2 1 PHD-finger ANT PF03374.14 KXL48714.1 - 0.039 14.3 0.0 0.084 13.2 0.0 1.5 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain IF2_N PF04760.15 KXL48714.1 - 0.043 13.6 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region Prok-RING_1 PF14446.6 KXL48714.1 - 0.11 12.5 4.0 0.26 11.2 4.0 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Velvet PF11754.8 KXL48715.1 - 2.4e-37 129.2 2.9 1.1e-27 97.6 0.2 2.0 1 1 1 2 2 2 2 Velvet factor SAP25 PF15476.6 KXL48715.1 - 0.061 13.0 0.0 0.083 12.5 0.0 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP25 CATSPERG PF15064.6 KXL48715.1 - 0.17 9.7 0.0 0.21 9.4 0.0 1.1 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit gamma BTB PF00651.31 KXL48716.1 - 4.5e-10 39.7 0.1 1.2e-08 35.1 0.0 2.5 2 1 1 3 3 3 1 BTB/POZ domain DUF3567 PF12091.8 KXL48716.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3567) Acetyltransf_4 PF13420.7 KXL48717.1 - 3.3e-15 56.6 0.0 3.7e-15 56.4 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXL48717.1 - 2.7e-06 27.6 0.0 3.4e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXL48717.1 - 0.00011 22.2 0.0 0.00015 21.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXL48717.1 - 0.00015 22.1 0.0 0.00024 21.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXL48717.1 - 0.087 12.8 0.0 0.18 11.8 0.0 1.6 1 1 0 1 1 1 0 FR47-like protein SH3_1 PF00018.28 KXL48718.1 - 2.9e-09 36.4 0.1 5.2e-09 35.6 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXL48718.1 - 1.3e-06 28.2 0.0 2.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXL48718.1 - 2.9e-06 26.8 0.0 5.6e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF2303 PF10065.9 KXL48718.1 - 0.0099 15.1 0.5 0.029 13.5 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2303) DUF4191 PF13829.6 KXL48718.1 - 0.12 11.7 1.7 0.18 11.1 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) SH3_10 PF17902.1 KXL48718.1 - 0.17 12.0 0.0 0.4 10.8 0.0 1.6 1 0 0 1 1 1 0 SH3 domain Response_reg PF00072.24 KXL48719.1 - 1.9e-20 73.1 0.0 2.5e-14 53.4 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain Beta-lactamase PF00144.24 KXL48720.1 - 0.0091 15.3 0.0 0.01 15.1 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Zn_clus PF00172.18 KXL48721.1 - 4.8e-10 39.4 7.6 4.8e-10 39.4 7.6 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXL48721.1 - 0.00011 21.1 0.6 0.00021 20.3 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cupin_2 PF07883.11 KXL48722.1 - 5.7e-14 51.6 0.1 5.7e-14 51.6 0.1 1.8 2 0 0 2 2 2 1 Cupin domain Cupin_6 PF12852.7 KXL48722.1 - 5.8e-05 22.9 0.0 6.4e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 KXL48722.1 - 0.0021 17.9 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 KXL48722.1 - 0.014 15.0 0.1 0.022 14.4 0.1 1.3 1 0 0 1 1 1 0 Cupin Cupin_3 PF05899.12 KXL48722.1 - 0.078 12.7 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) ARD PF03079.14 KXL48722.1 - 0.098 12.8 0.9 0.2 11.8 0.0 1.8 1 1 1 2 2 2 0 ARD/ARD' family INCENP_ARK-bind PF03941.15 KXL48722.1 - 0.53 10.3 2.4 0.94 9.5 2.4 1.4 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region DMRT-like PF15791.5 KXL48723.1 - 0.34 11.4 7.5 0.88 10.0 7.5 1.7 1 0 0 1 1 1 0 Doublesex-and mab-3-related transcription factor C1 and C2 TMEM171 PF15471.6 KXL48723.1 - 5.3 5.9 8.9 3 6.7 4.9 2.0 2 0 0 2 2 2 0 Transmembrane protein family 171 DUF4551 PF15087.6 KXL48723.1 - 6.6 5.4 10.9 8.6 5.1 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) tRNA-synt_1d PF00750.19 KXL48726.1 - 3e-96 322.4 6.3 8.4e-58 196.0 4.5 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.15 KXL48726.1 - 1.4e-23 83.3 0.6 1.4e-23 83.3 0.6 2.6 2 0 0 2 2 2 1 DALR anticodon binding domain Glyco_transf_90 PF05686.12 KXL48726.1 - 7.4e-13 48.2 1.9 7.6e-12 44.8 0.6 2.8 2 1 0 2 2 2 1 Glycosyl transferase family 90 Arg_tRNA_synt_N PF03485.16 KXL48726.1 - 1e-05 26.0 0.0 2.2e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain MRP-S27 PF10037.9 KXL48726.1 - 0.1 11.4 5.0 0.23 10.3 5.0 1.5 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 PDE4_UCR PF18100.1 KXL48726.1 - 0.11 13.2 1.5 0.33 11.6 1.5 1.8 1 0 0 1 1 1 0 Phosphodiesterase 4 upstream conserved regions (UCR) LprI PF07007.12 KXL48726.1 - 0.17 12.6 2.5 0.67 10.6 2.5 2.1 1 1 0 1 1 1 0 Lysozyme inhibitor LprI GvpL_GvpF PF06386.11 KXL48726.1 - 2.7 7.8 5.2 5 7.0 5.2 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Abhydrolase_6 PF12697.7 KXL48727.1 - 4.1e-06 27.6 0.1 8.4e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXL48727.1 - 4.1e-05 23.3 0.1 7.9e-05 22.4 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 KXL48727.1 - 0.0025 17.7 0.1 0.0097 15.8 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase Lipase_3 PF01764.25 KXL48727.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DEAD PF00270.29 KXL48729.1 - 6e-42 143.4 1.8 6e-42 143.4 1.8 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXL48729.1 - 1.1e-31 109.4 1.0 1.3e-30 106.0 0.2 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL48729.1 - 2.6e-07 30.8 1.5 2.9e-07 30.6 0.1 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KXL48729.1 - 1e-05 24.4 0.1 1.7e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain CMS1 PF14617.6 KXL48729.1 - 0.015 14.6 1.7 0.016 14.5 0.1 2.0 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit FAD_binding_1 PF00667.20 KXL48730.1 - 1.8e-47 161.8 0.0 3.8e-47 160.7 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KXL48730.1 - 2.3e-08 34.6 0.0 1.4e-06 28.9 0.0 2.6 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain zf-C2H2_assoc PF16606.5 KXL48730.1 - 0.089 13.0 0.1 0.27 11.5 0.1 1.8 1 0 0 1 1 1 0 Unstructured conserved, between two C2H2-type zinc-fingers Clathrin_lg_ch PF01086.17 KXL48732.1 - 2e-73 247.2 0.0 2.3e-73 247.1 0.0 1.0 1 0 0 1 1 1 1 Clathrin light chain XPG_I_2 PF12813.7 KXL48732.1 - 0.094 12.2 0.3 0.13 11.7 0.3 1.2 1 0 0 1 1 1 0 XPG domain containing AMP-binding PF00501.28 KXL48733.1 - 1.1e-77 261.4 0.0 1.5e-77 261.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXL48733.1 - 8.8e-16 58.6 0.2 2.7e-15 57.1 0.2 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FPN1 PF06963.12 KXL48734.1 - 4.4e-113 378.1 24.7 6e-113 377.7 24.7 1.2 1 0 0 1 1 1 1 Ferroportin1 (FPN1) PHD PF00628.29 KXL48735.1 - 2.7e-09 36.8 10.5 6.4e-09 35.6 10.5 1.7 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KXL48735.1 - 0.0052 16.3 5.8 0.012 15.1 5.8 1.6 1 0 0 1 1 1 1 PHD-finger WSD PF15613.6 KXL48735.1 - 0.0083 16.6 0.1 0.0083 16.6 0.1 3.4 2 1 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif zf-RING_9 PF13901.6 KXL48735.1 - 0.094 12.7 8.0 0.15 12.0 8.0 1.4 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon RNA_POL_M_15KD PF02150.16 KXL48735.1 - 1.6 8.7 7.3 2.9 7.9 0.1 3.4 2 1 1 3 3 3 0 RNA polymerases M/15 Kd subunit C1_2 PF03107.16 KXL48735.1 - 8 6.9 10.9 1.8 9.0 6.0 2.2 2 0 0 2 2 2 0 C1 domain DNA_pol_B_palm PF14792.6 KXL48736.1 - 7e-31 106.8 0.0 1.7e-30 105.6 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 KXL48736.1 - 2.9e-22 78.6 0.1 1.1e-21 76.8 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 KXL48736.1 - 2.1e-18 65.9 0.1 4e-18 65.0 0.1 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 KXL48736.1 - 2.9e-16 59.6 0.0 9.2e-16 58.0 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain BRCT PF00533.26 KXL48736.1 - 3.7e-06 27.2 0.0 8.6e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KXL48736.1 - 9.3e-05 22.8 0.0 0.00021 21.7 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain NTP_transf_2 PF01909.23 KXL48736.1 - 0.003 17.8 0.0 0.0091 16.3 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain LIG3_BRCT PF16759.5 KXL48736.1 - 0.086 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 KXL48736.1 - 0.11 12.4 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain Sld5 PF05916.11 KXL48737.1 - 8.9e-10 39.0 0.0 1.4e-09 38.4 0.0 1.4 1 1 0 1 1 1 1 GINS complex protein Zn_clus PF00172.18 KXL48740.1 - 0.0016 18.5 4.7 0.0016 18.5 4.7 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TF_Zn_Ribbon PF08271.12 KXL48740.1 - 0.049 13.1 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding RNB PF00773.19 KXL48741.1 - 5.1e-98 328.4 0.1 7e-98 327.9 0.1 1.2 1 0 0 1 1 1 1 RNB domain Rrp44_S1 PF17215.3 KXL48741.1 - 2.2e-30 104.4 0.2 6.3e-30 103.0 0.2 1.8 1 0 0 1 1 1 1 S1 domain Rrp44_CSD1 PF17216.3 KXL48741.1 - 6.6e-27 94.0 0.4 1.5e-26 92.8 0.1 1.8 2 0 0 2 2 2 1 Rrp44-like cold shock domain OB_Dis3 PF17849.1 KXL48741.1 - 2.3e-20 72.4 0.0 8.2e-20 70.6 0.0 2.0 2 0 0 2 2 2 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 KXL48741.1 - 2.6e-08 33.9 0.0 9.8e-05 22.5 0.0 2.9 2 0 0 2 2 2 2 Cold shock domain PIN_4 PF13638.6 KXL48741.1 - 2.8e-08 34.1 2.5 4.6e-08 33.4 0.0 2.6 3 0 0 3 3 3 1 PIN domain CRC_subunit PF08624.10 KXL48742.1 - 1.6e-54 184.0 0.1 2.8e-54 183.2 0.1 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit CBFD_NFYB_HMF PF00808.23 KXL48744.1 - 1.5e-09 38.0 0.1 2.5e-09 37.3 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KXL48744.1 - 6e-05 23.1 0.0 0.00014 21.9 0.0 1.4 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KXL48744.1 - 0.00025 21.4 0.3 0.0025 18.2 0.0 2.2 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Phyto_Pns9_10 PF05878.11 KXL48744.1 - 0.046 12.9 0.9 0.068 12.3 0.9 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 CAP_GLY PF01302.25 KXL48745.1 - 1.1e-16 60.5 0.0 2e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 KXL48745.1 - 7.4e-11 42.1 16.3 0.0011 19.3 0.1 6.0 4 2 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXL48745.1 - 0.0002 21.0 15.5 0.12 12.1 1.2 6.2 1 1 4 5 5 5 3 Leucine rich repeat LRR_9 PF14580.6 KXL48745.1 - 0.0003 20.4 2.5 0.1 12.1 0.4 2.8 1 1 1 2 2 2 2 Leucine-rich repeat Yuri_gagarin PF15934.5 KXL48745.1 - 0.034 14.0 0.1 0.085 12.7 0.1 1.5 1 0 0 1 1 1 0 Yuri gagarin LRR_6 PF13516.6 KXL48745.1 - 0.04 14.0 4.6 10 6.5 0.0 4.9 5 0 0 5 5 5 0 Leucine Rich repeat SF3A2 PF16835.5 KXL48746.1 - 1.7e-37 127.7 0.2 2.5e-37 127.1 0.2 1.2 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 KXL48746.1 - 1.1e-05 25.7 0.5 2e-05 24.8 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 KXL48746.1 - 0.02 14.8 0.2 0.03 14.2 0.2 1.3 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein PRP4 PF08799.11 KXL48746.1 - 0.061 12.9 1.5 0.11 12.1 1.5 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like PI-PLC-X PF00388.19 KXL48747.1 - 1.3e-14 54.0 0.0 2e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Glyco_hydro_11 PF00457.17 KXL48748.1 - 1.8e-59 200.4 12.6 2.1e-59 200.1 12.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Methyltransf_4 PF02390.17 KXL48749.1 - 3.8e-54 182.8 0.0 4.4e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 KXL48749.1 - 0.00043 20.9 0.0 0.00079 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL48749.1 - 0.002 18.8 0.0 0.0046 17.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KXL48749.1 - 0.0028 17.2 0.0 0.007 15.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KXL48749.1 - 0.012 15.4 0.0 0.017 14.9 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KXL48749.1 - 0.02 14.9 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KXL48749.1 - 0.023 15.4 0.0 0.075 13.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain DUF1015 PF06245.11 KXL48749.1 - 0.14 11.0 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1015) Aminotran_1_2 PF00155.21 KXL48753.1 - 2.6e-29 102.6 0.0 3e-29 102.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KXL48753.1 - 2.7e-06 26.2 0.0 3.8e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KXL48753.1 - 1.6e-05 24.0 0.0 2.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KXL48753.1 - 0.077 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase GlgX_C PF18390.1 KXL48753.1 - 0.17 11.7 0.0 0.4 10.5 0.0 1.6 1 0 0 1 1 1 0 Glycogen debranching enzyme C-terminal domain PFU PF09070.11 KXL48754.1 - 4.4e-41 139.7 0.1 8.2e-41 138.8 0.1 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.11 KXL48754.1 - 1.7e-38 132.5 4.0 2.2e-38 132.1 4.0 1.1 1 0 0 1 1 1 1 PUL domain WD40 PF00400.32 KXL48754.1 - 5.7e-31 106.1 9.3 3.1e-07 31.0 0.3 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL48754.1 - 0.049 13.9 0.3 3.5 8.0 0.0 3.2 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain FBA_3 PF08268.12 KXL48754.1 - 0.19 11.7 0.0 1.5 8.8 0.0 2.1 2 0 0 2 2 2 0 F-box associated domain Abhydrolase_1 PF00561.20 KXL48755.1 - 3.6e-22 79.2 0.1 8e-22 78.1 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KXL48755.1 - 8e-21 73.4 0.5 1.7e-20 72.3 0.5 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 KXL48755.1 - 0.00034 20.0 0.0 0.037 13.3 0.0 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 KXL48755.1 - 0.0015 18.2 0.0 0.036 13.7 0.0 2.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KXL48755.1 - 0.0062 16.4 0.1 0.37 10.5 0.0 2.4 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Pet191_N PF10203.9 KXL48756.1 - 1.1e-28 99.3 1.8 1.4e-28 99.0 1.8 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 KXL48756.1 - 1.5 8.9 5.4 9.7 6.3 0.2 3.0 1 1 2 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, SSF PF00474.17 KXL48757.1 - 5.1e-07 28.9 2.9 5.5e-07 28.8 2.9 1.0 1 0 0 1 1 1 1 Sodium:solute symporter family FAD_binding_3 PF01494.19 KXL48759.1 - 0.0014 17.9 0.0 0.0014 17.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DUF295 PF03478.18 KXL48759.1 - 0.12 12.0 1.7 0.31 10.7 0.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF295) Protoglobin PF11563.8 KXL48760.1 - 4.8e-47 159.8 0.0 5.5e-47 159.6 0.0 1.0 1 0 0 1 1 1 1 Protoglobin Abhydrolase_3 PF07859.13 KXL48761.1 - 1e-30 107.2 0.0 1.3e-30 106.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXL48761.1 - 0.0078 15.1 0.0 0.026 13.4 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KXL48761.1 - 0.024 14.1 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Thioesterase PF00975.20 KXL48761.1 - 0.048 13.8 0.0 0.074 13.2 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain CoA_trans PF01144.23 KXL48764.1 - 9.9e-98 325.8 1.7 7.8e-58 195.4 0.3 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 KXL48764.1 - 0.017 15.0 0.9 0.036 14.0 0.0 1.9 2 0 0 2 2 2 0 Acetyl-CoA hydrolase/transferase C-terminal domain Fungal_trans PF04082.18 KXL48766.1 - 3.3e-09 36.2 0.1 5.3e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL48766.1 - 1.6e-07 31.4 10.5 3.3e-07 30.3 10.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-CHY PF05495.12 KXL48768.1 - 0.13 12.7 0.4 0.13 12.7 0.4 2.3 2 0 0 2 2 2 0 CHY zinc finger HET PF06985.11 KXL48769.1 - 0.0037 17.6 0.0 0.004 17.5 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) UNC-93 PF05978.16 KXL48771.1 - 3.1e-12 46.5 7.6 3.1e-12 46.5 7.6 2.0 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KXL48771.1 - 2.3e-10 39.9 32.9 2.3e-10 39.9 32.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Glucosamine_iso PF01182.20 KXL48772.1 - 9.8e-20 71.4 0.0 1.6e-19 70.7 0.0 1.3 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase BIR PF00653.21 KXL48774.1 - 1e-41 141.4 2.0 6e-20 71.7 0.1 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Dicty_REP PF05086.12 KXL48774.1 - 0.4 8.6 2.1 0.67 7.9 2.1 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tam41_Mmp37 PF09139.11 KXL48775.1 - 1.2e-122 409.4 0.0 1.6e-122 409.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial Peptidase_M18 PF02127.15 KXL48776.1 - 3.2e-159 530.4 0.0 6.2e-159 529.4 0.0 1.4 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) DUF202 PF02656.15 KXL48777.1 - 1e-14 54.7 3.5 5.7e-14 52.3 3.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) PC_rep PF01851.22 KXL48777.1 - 0.19 12.2 3.0 4.3 8.0 0.4 3.1 3 0 0 3 3 3 0 Proteasome/cyclosome repeat p450 PF00067.22 KXL48780.1 - 1.9e-69 234.6 0.0 2.6e-69 234.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CMD PF02627.20 KXL48781.1 - 1.3e-06 28.4 0.6 1.2e-05 25.3 0.1 2.1 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Zn_clus PF00172.18 KXL48782.1 - 3.8e-10 39.7 9.3 7.1e-10 38.8 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAR1 PF03101.15 KXL48782.1 - 1.6e-07 31.9 0.7 4.4e-07 30.5 0.7 1.8 1 0 0 1 1 1 1 FAR1 DNA-binding domain Retrotran_gag_2 PF14223.6 KXL48782.1 - 0.00091 18.9 0.0 0.0062 16.2 0.0 2.0 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type DNA_pol_phi PF04931.13 KXL48782.1 - 1.1 7.2 3.8 1.7 6.6 3.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi TFIIA PF03153.13 KXL48782.1 - 8 6.3 26.8 1.4 8.8 16.7 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MFS_1 PF07690.16 KXL48783.1 - 0.002 17.1 0.1 0.0047 15.9 0.1 1.6 1 0 0 1 1 1 1 Major Facilitator Superfamily Y_phosphatase3 PF13350.6 KXL48784.1 - 3e-40 138.6 0.0 3.5e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KXL48784.1 - 2.3e-07 30.6 0.0 5.1e-07 29.4 0.0 1.5 2 0 0 2 2 2 1 Tyrosine phosphatase family Myotub-related PF06602.14 KXL48784.1 - 0.00026 20.0 0.0 0.0004 19.4 0.0 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 KXL48784.1 - 0.00062 19.4 0.0 0.00098 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KXL48784.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Eisosome1 PF12757.7 KXL48785.1 - 3.4e-39 134.0 16.5 3.4e-39 134.0 16.5 4.4 5 0 0 5 5 5 1 Eisosome protein 1 HCNGP PF07818.13 KXL48786.1 - 8.9e-23 80.8 0.0 1.1e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 HCNGP-like protein Vir_act_alpha_C PF10400.9 KXL48786.1 - 0.04 14.6 0.2 0.074 13.7 0.0 1.5 2 0 0 2 2 2 0 Virulence activator alpha C-term Proteasome PF00227.26 KXL48787.1 - 3.4e-29 101.7 0.0 4e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit eIF3_subunit PF08597.10 KXL48789.1 - 1.3e-67 228.3 30.1 1.6e-67 227.9 30.1 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit SYCP2_ARLD PF18581.1 KXL48789.1 - 0.03 14.3 0.5 0.052 13.6 0.5 1.3 1 0 0 1 1 1 0 Synaptonemal complex 2 armadillo-repeat-like domain DUF4502 PF14950.6 KXL48789.1 - 1.2 8.5 17.9 0.049 13.1 9.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4502) Vfa1 PF08432.10 KXL48789.1 - 4.2 7.7 24.6 3.6 7.9 1.1 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Presenilin PF01080.17 KXL48789.1 - 5.1 5.8 14.6 0.52 9.0 8.8 1.9 2 0 0 2 2 2 0 Presenilin DUF87 PF01935.17 KXL48789.1 - 7.6 6.6 13.9 1.2 9.2 7.2 2.0 1 1 0 2 2 2 0 Helicase HerA, central domain Clathrin PF00637.20 KXL48790.1 - 5e-199 652.2 35.1 2.1e-32 112.0 3.6 7.8 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 KXL48790.1 - 4.9e-31 105.5 0.6 2.1e-08 34.1 0.1 6.8 6 0 0 6 6 6 4 Clathrin propeller repeat Clathrin_H_link PF13838.6 KXL48790.1 - 9.5e-31 105.5 1.6 9.5e-31 105.5 1.6 3.2 3 1 1 4 4 4 1 Clathrin-H-link Clathrin-link PF09268.10 KXL48790.1 - 8e-05 21.9 0.4 0.00024 20.4 0.4 1.9 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Vps39_1 PF10366.9 KXL48790.1 - 0.00016 21.9 6.0 5.8 7.2 0.0 5.7 4 1 1 5 5 5 1 Vacuolar sorting protein 39 domain 1 Coatomer_WDAD PF04053.14 KXL48790.1 - 0.0011 18.1 5.5 0.89 8.5 0.1 4.2 4 0 0 4 4 4 2 Coatomer WD associated region TPR_7 PF13176.6 KXL48790.1 - 0.048 13.7 6.8 30 4.9 0.0 6.9 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 KXL48790.1 - 2.1 8.9 4.9 2.5e+02 2.4 0.2 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXL48790.1 - 3.7 7.9 9.3 6.6 7.1 0.0 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXL48790.1 - 7.2 7.7 20.9 11 7.1 0.1 8.3 10 1 0 10 10 8 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXL48790.1 - 9.8 6.7 12.7 1.5 9.2 0.0 5.9 8 0 0 8 8 5 0 Tetratricopeptide repeat MutS_V PF00488.21 KXL48791.1 - 3.5e-66 222.8 1.2 5.8e-66 222.1 1.2 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXL48791.1 - 1.3e-32 113.6 4.1 1.3e-32 113.6 4.1 2.4 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 KXL48791.1 - 5.3e-10 39.7 0.1 1.2e-09 38.5 0.1 1.6 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KXL48791.1 - 0.00012 22.4 0.1 0.00034 20.9 0.1 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA_27 PF13514.6 KXL48791.1 - 0.00063 19.4 0.2 1.4 8.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KXL48791.1 - 0.015 15.0 0.1 0.036 13.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain DnaJ PF00226.31 KXL48792.1 - 8e-20 70.7 4.9 1.2e-19 70.1 4.9 1.3 1 0 0 1 1 1 1 DnaJ domain TPR_19 PF14559.6 KXL48793.1 - 6e-09 36.3 0.8 2.8e-08 34.1 0.1 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXL48793.1 - 9e-09 34.8 0.2 1.6e-06 27.7 0.3 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXL48793.1 - 7.7e-07 29.4 2.8 0.0031 18.2 0.1 4.2 1 1 4 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXL48793.1 - 6.2e-06 25.8 0.1 0.00045 19.9 0.3 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXL48793.1 - 5.2e-05 22.8 0.3 0.037 13.7 0.0 3.1 3 1 1 4 4 4 2 TPR repeat TPR_8 PF13181.6 KXL48793.1 - 7.8e-05 22.6 0.0 0.0007 19.6 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXL48793.1 - 8e-05 22.8 0.1 0.0016 18.7 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXL48793.1 - 8.4e-05 23.1 1.0 0.001 19.6 0.0 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.6 KXL48793.1 - 0.00026 21.2 0.0 0.0032 17.8 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXL48793.1 - 0.0027 17.6 0.1 0.077 13.1 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXL48793.1 - 0.0027 18.0 0.4 0.021 15.1 0.1 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat ChAPs PF09295.10 KXL48793.1 - 0.0028 16.7 0.1 0.0046 16.0 0.1 1.3 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.6 KXL48793.1 - 0.0029 18.1 0.2 2.1 9.2 0.0 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXL48793.1 - 0.0082 16.3 0.2 0.021 15.0 0.2 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat Phage_Gp23 PF10669.9 KXL48794.1 - 0.17 12.2 3.6 0.26 11.6 3.6 1.3 1 1 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Atg14 PF10186.9 KXL48794.1 - 0.99 8.4 5.6 1.2 8.2 5.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sds3 PF08598.11 KXL48796.1 - 1.1e-09 38.6 0.0 1.3e-09 38.4 0.0 1.1 1 0 0 1 1 1 1 Sds3-like DUF3053 PF11254.8 KXL48796.1 - 0.082 12.5 0.5 0.15 11.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3053) DEC-1_N PF04625.13 KXL48796.1 - 0.37 9.8 6.6 0.42 9.6 6.6 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Glyco_hydro_3 PF00933.21 KXL48797.1 - 4.5e-58 197.1 0.0 6.4e-58 196.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KXL48797.1 - 2.6e-50 171.2 0.0 5e-50 170.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KXL48797.1 - 2.1e-21 75.8 0.2 1.1e-20 73.5 0.1 2.2 2 0 0 2 2 2 1 Fibronectin type III-like domain Sugar-bind PF04198.13 KXL48797.1 - 0.016 14.3 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain Aa_trans PF01490.18 KXL48799.1 - 6.8e-26 90.9 20.3 1e-25 90.4 20.3 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Nup96 PF12110.8 KXL48800.1 - 4.9e-60 203.1 0.6 8.2e-60 202.4 0.6 1.4 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 KXL48800.1 - 4.6e-49 166.4 0.0 7.6e-49 165.6 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 KXL48800.1 - 2.6e-28 98.7 199.2 1.9e-09 38.2 33.5 10.8 6 2 7 13 13 13 6 Nucleoporin FG repeat region TPP_enzyme_N PF02776.18 KXL48802.1 - 9.9e-35 119.7 0.1 1.4e-34 119.1 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXL48802.1 - 5.9e-18 64.9 0.0 1.2e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KXL48802.1 - 2.3e-13 50.2 0.0 1.4e-12 47.6 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Peptidase_M20 PF01546.28 KXL48803.1 - 7.6e-34 117.2 0.0 1e-33 116.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXL48803.1 - 3.8e-10 39.6 0.0 8.4e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KXL48803.1 - 0.00071 19.3 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Sugar_tr PF00083.24 KXL48804.1 - 5.6e-83 279.3 16.5 6.5e-83 279.1 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL48804.1 - 7.1e-15 54.8 42.3 2.2e-11 43.3 32.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXL48804.1 - 0.0017 17.3 1.9 0.0017 17.3 1.9 2.2 2 0 0 2 2 2 2 MFS_1 like family OATP PF03137.20 KXL48804.1 - 0.04 12.2 12.0 0.024 12.9 1.7 2.5 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family TFA2_Winged_2 PF18121.1 KXL48805.1 - 4.5e-21 74.3 0.0 1.2e-20 72.9 0.0 1.8 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 KXL48805.1 - 5.2e-11 42.7 0.2 1.1e-10 41.6 0.2 1.6 1 0 0 1 1 1 1 TFIIE beta subunit core domain TPR_MLP1_2 PF07926.12 KXL48806.1 - 6.1e-33 113.6 26.9 6.1e-33 113.6 26.9 17.4 7 6 10 18 18 18 5 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 KXL48806.1 - 0.0017 18.7 5.4 0.0017 18.7 5.4 15.8 4 2 7 15 15 15 4 Autophagy protein 16 (ATG16) Sec63 PF02889.16 KXL48807.1 - 1.2e-32 113.1 0.0 1.7e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 KXL48807.1 - 2.3e-22 79.6 0.0 4.7e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KXL48807.1 - 6e-10 39.4 0.0 1.4e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXL48807.1 - 8.2e-06 26.1 0.0 3.4e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.6 KXL48807.1 - 0.00025 21.6 0.1 0.0007 20.1 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_19 PF13245.6 KXL48807.1 - 0.0091 16.3 0.0 0.05 13.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXL48807.1 - 0.0093 16.2 0.0 0.048 13.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXL48807.1 - 0.023 14.4 0.0 0.053 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain DNA_pol_lambd_f PF10391.9 KXL48807.1 - 0.052 13.4 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda PilO PF04350.13 KXL48807.1 - 0.17 12.1 0.1 0.34 11.1 0.1 1.4 1 0 0 1 1 1 0 Pilus assembly protein, PilO UvrD-helicase PF00580.21 KXL48807.1 - 0.17 11.4 0.0 0.46 10.0 0.0 1.6 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Nuc_sug_transp PF04142.15 KXL48808.1 - 4.3e-93 311.9 5.6 5.9e-93 311.5 5.6 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 KXL48808.1 - 7.8e-09 35.2 9.2 3.8e-08 32.9 9.1 1.9 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.16 KXL48808.1 - 9.3e-05 21.9 10.5 0.0041 16.5 2.7 2.3 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 KXL48808.1 - 0.00012 22.3 3.6 0.00012 22.3 3.6 2.5 2 1 0 2 2 2 1 EamA-like transporter family PUNUT PF16913.5 KXL48808.1 - 0.00013 21.4 9.5 0.002 17.4 0.4 2.3 2 0 0 2 2 2 2 Purine nucleobase transmembrane transport EmrE PF13536.6 KXL48808.1 - 0.0071 16.0 0.1 0.0071 16.0 0.1 2.2 2 0 0 2 2 2 1 Putative multidrug resistance efflux transporter Aminotran_1_2 PF00155.21 KXL48809.1 - 2.2e-35 122.5 0.0 3e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KXL48809.1 - 0.17 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Methyltransf_23 PF13489.6 KXL48810.1 - 1.8e-20 73.4 0.0 2.8e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL48810.1 - 1.5e-19 70.4 0.0 2.4e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL48810.1 - 5.2e-16 59.1 0.0 1e-15 58.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL48810.1 - 2.3e-14 53.9 0.0 4.7e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL48810.1 - 1.4e-13 50.9 0.0 1.9e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 KXL48810.1 - 9.9e-05 22.0 0.0 0.00014 21.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.13 KXL48810.1 - 0.00017 21.1 0.0 0.00022 20.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KXL48810.1 - 0.0036 16.9 0.0 0.0071 15.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KXL48810.1 - 0.0062 15.9 0.0 0.0083 15.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 KXL48810.1 - 0.0089 15.0 0.0 0.018 14.0 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) CMAS PF02353.20 KXL48810.1 - 0.012 14.9 0.0 0.027 13.8 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MCU PF04678.13 KXL48811.1 - 8.9e-26 91.1 0.1 8.9e-26 91.1 0.1 2.2 3 0 0 3 3 3 1 Mitochondrial calcium uniporter Mito_carr PF00153.27 KXL48812.1 - 2.8e-63 209.9 1.9 1.8e-21 75.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXL48812.1 - 0.065 12.4 4.6 5.9 6.0 0.2 3.5 2 1 0 3 3 3 0 Gammaproteobacterial serine protease DUF3042 PF11240.8 KXL48812.1 - 0.089 12.8 0.5 20 5.3 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) P5CR_dimer PF14748.6 KXL48812.1 - 0.12 12.7 0.3 0.38 11.0 0.1 1.8 2 0 0 2 2 2 0 Pyrroline-5-carboxylate reductase dimerisation Aldedh PF00171.22 KXL48813.1 - 7.5e-150 499.5 0.0 8.4e-150 499.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cu-oxidase_3 PF07732.15 KXL48814.1 - 2.2e-42 143.8 6.2 1.3e-40 138.1 0.7 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXL48814.1 - 6e-39 132.9 5.2 2.6e-38 130.8 0.1 3.5 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 KXL48814.1 - 5.1e-33 114.4 0.2 1.5e-32 112.9 0.2 1.7 1 0 0 1 1 1 1 Multicopper oxidase V_ATPase_I PF01496.19 KXL48815.1 - 0 1083.9 0.0 0 1083.7 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CheZ PF04344.13 KXL48815.1 - 0.00076 19.4 0.9 0.0059 16.5 0.1 2.2 2 0 0 2 2 2 1 Chemotaxis phosphatase, CheZ Filament PF00038.21 KXL48815.1 - 0.01 15.4 3.0 0.71 9.4 0.2 2.3 2 0 0 2 2 2 0 Intermediate filament protein DUF16 PF01519.16 KXL48815.1 - 0.018 15.5 0.9 0.37 11.3 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF16 Baculo_PEP_C PF04513.12 KXL48815.1 - 0.035 14.2 1.2 1.3 9.1 0.1 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Serine_rich PF08824.10 KXL48815.1 - 0.036 14.1 2.1 0.042 13.9 0.4 1.9 2 0 0 2 2 2 0 Serine rich protein interaction domain DUF3450 PF11932.8 KXL48815.1 - 0.051 12.9 3.0 0.061 12.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DivIC PF04977.15 KXL48815.1 - 0.093 12.5 0.1 0.64 9.8 0.1 2.4 1 0 0 1 1 1 0 Septum formation initiator DUF4988 PF16378.5 KXL48815.1 - 0.31 10.7 1.6 0.3 10.7 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF1664 PF07889.12 KXL48815.1 - 0.4 10.7 3.1 13 5.9 0.1 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) GIT_CC PF16559.5 KXL48815.1 - 1 9.3 3.7 6.8 6.6 0.2 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor HMMR_N PF15905.5 KXL48815.1 - 5.2 6.5 5.8 15 4.9 0.3 2.3 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal ZapB PF06005.12 KXL48815.1 - 7 7.2 6.3 2.7 8.5 0.2 2.6 3 0 0 3 3 3 0 Cell division protein ZapB PseudoU_synth_1 PF01416.20 KXL48816.1 - 9.8e-36 122.5 0.0 8.1e-33 113.1 0.0 2.8 3 0 0 3 3 3 2 tRNA pseudouridine synthase PIG-H PF10181.9 KXL48817.1 - 5.5e-27 93.4 0.4 9.1e-27 92.7 0.4 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Peptidase_S15 PF02129.18 KXL48820.1 - 1e-25 90.9 0.5 6.2e-09 35.8 0.0 3.2 1 1 2 3 3 3 3 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 KXL48820.1 - 1e-13 51.7 0.0 3.1e-12 46.9 0.0 2.1 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain DHHC PF01529.20 KXL48821.1 - 2 8.6 8.9 1 9.4 3.5 2.1 1 1 1 2 2 2 0 DHHC palmitoyltransferase Peptidase_U4 PF03419.13 KXL48821.1 - 6.3 6.0 8.2 44 3.2 8.2 2.1 1 1 0 1 1 1 0 Sporulation factor SpoIIGA YjhX_toxin PF09857.9 KXL48822.1 - 0.039 13.9 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative toxin of bacterial toxin-antitoxin pair Cytochrom_B561 PF03188.16 KXL48823.1 - 0.0027 17.8 12.6 0.0063 16.6 12.6 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 KXL48823.1 - 0.59 10.0 10.4 1.6 8.5 10.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) ABC_membrane_2 PF06472.15 KXL48824.1 - 2.8e-102 341.7 1.3 4.4e-102 341.1 1.3 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KXL48824.1 - 4.2e-15 56.5 0.0 8.8e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXL48824.1 - 9.5e-05 22.3 0.0 0.00059 19.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KXL48824.1 - 0.024 15.1 0.4 0.099 13.1 0.4 2.0 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXL48824.1 - 0.037 13.8 0.0 0.13 12.0 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain RuvB_N PF05496.12 KXL48824.1 - 0.041 13.6 0.1 0.74 9.5 0.0 2.9 4 0 0 4 4 4 0 Holliday junction DNA helicase RuvB P-loop domain Reticulon PF02453.17 KXL48824.1 - 0.05 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Reticulon AAA_16 PF13191.6 KXL48824.1 - 0.07 13.5 1.0 0.46 10.8 0.1 2.4 2 0 0 2 2 2 0 AAA ATPase domain SMC_N PF02463.19 KXL48824.1 - 0.1 12.0 0.2 0.26 10.7 0.0 1.7 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF1059 PF06348.11 KXL48825.1 - 0.0058 16.8 1.6 0.014 15.6 0.1 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1059) SLM4 PF16818.5 KXL48825.1 - 0.079 12.9 0.3 0.91 9.5 0.3 2.2 1 1 0 1 1 1 0 Protein SLM4 PQQ PF01011.21 KXL48825.1 - 0.11 12.5 0.0 0.35 10.9 0.0 1.9 2 0 0 2 2 2 0 PQQ enzyme repeat ATF7IP_BD PF16788.5 KXL48825.1 - 0.28 11.2 3.6 0.43 10.6 3.6 1.3 1 0 0 1 1 1 0 ATF-interacting protein binding domain Glyco_hydro_28 PF00295.17 KXL48827.1 - 2.7e-91 306.0 19.2 3.2e-91 305.8 19.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 zf_CopZ PF18423.1 KXL48827.1 - 0.035 14.1 0.0 0.089 12.8 0.0 1.6 1 0 0 1 1 1 0 Zinc binding domain HLH PF00010.26 KXL48828.1 - 5.2e-09 35.9 0.0 1.7e-08 34.3 0.0 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ctf8 PF09696.10 KXL48829.1 - 4e-36 124.5 0.1 5.3e-34 117.6 0.1 2.3 1 1 0 1 1 1 1 Ctf8 p450 PF00067.22 KXL48830.1 - 9.7e-72 242.2 0.0 1.2e-71 241.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BCDHK_Adom3 PF10436.9 KXL48831.1 - 4.8e-74 247.6 0.0 6.7e-74 247.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KXL48831.1 - 1.6e-13 51.1 0.0 3.5e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KXL48831.1 - 0.038 13.8 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AMP-binding PF00501.28 KXL48833.1 - 2.1e-91 306.6 0.2 2.6e-91 306.4 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXL48833.1 - 5.2e-26 91.4 0.3 1.7e-24 86.6 0.1 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KXL48833.1 - 6.8e-18 64.3 0.3 6.8e-18 64.3 0.3 1.8 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus DUF1967 PF09269.11 KXL48833.1 - 0.13 12.2 0.0 0.67 9.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) WD40 PF00400.32 KXL48835.1 - 3.2e-17 62.6 9.6 0.0055 17.5 0.1 8.3 9 0 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL48835.1 - 7.5e-05 23.0 1.4 2 8.8 0.1 4.8 3 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF2153 PF09921.9 KXL48835.1 - 0.021 14.7 0.1 0.05 13.4 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2153) Aa_trans PF01490.18 KXL48837.1 - 9.1e-29 100.4 22.2 1.3e-28 99.9 22.2 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CstA PF02554.14 KXL48837.1 - 6.4e-06 25.3 11.6 1.1e-05 24.5 11.6 1.3 1 0 0 1 1 1 1 Carbon starvation protein CstA Acyl-CoA_dh_1 PF00441.24 KXL48838.1 - 1.4e-17 64.2 0.0 4.6e-17 62.6 0.0 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AidB_N PF18158.1 KXL48838.1 - 1.4e-14 54.4 0.0 3e-14 53.2 0.0 1.5 1 1 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_M PF02770.19 KXL48838.1 - 1.5e-11 44.4 0.0 6e-11 42.4 0.0 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Zn_clus PF00172.18 KXL48839.1 - 0.00062 19.8 11.8 0.0011 19.1 11.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3112 PF11309.8 KXL48840.1 - 1.9e-10 40.6 11.3 8.2e-08 32.0 0.0 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF3112) MIG-14_Wnt-bd PF06664.12 KXL48840.1 - 0.31 10.2 17.7 1.3 8.2 17.8 2.0 1 1 0 1 1 1 0 Wnt-binding factor required for Wnt secretion DUF2631 PF10939.8 KXL48840.1 - 1.3 8.9 3.5 3.3 7.6 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2631) S_4TM PF18159.1 KXL48840.1 - 3.4 6.9 10.2 0.39 10.0 2.2 2.7 1 1 1 3 3 3 0 SMODS-associating 4TM effector domain RDD PF06271.12 KXL48840.1 - 9.5 6.4 21.0 0.33 11.2 8.6 3.4 2 2 1 3 3 3 0 RDD family 3Beta_HSD PF01073.19 KXL48841.1 - 1.8e-18 66.5 0.0 2.4e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXL48841.1 - 6e-18 65.2 0.0 9.4e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXL48841.1 - 4.2e-10 39.5 0.0 1.8e-08 34.2 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KXL48841.1 - 9.4e-08 31.5 0.0 1.3e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KXL48841.1 - 1.6e-07 31.4 0.0 2.7e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXL48841.1 - 0.0017 17.9 0.0 0.41 10.2 0.0 2.3 2 1 0 2 2 2 2 NmrA-like family DUF2016 PF09436.10 KXL48841.1 - 0.0026 17.5 0.0 0.014 15.2 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF2016) adh_short PF00106.25 KXL48841.1 - 0.033 13.7 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.10 KXL48841.1 - 0.097 12.6 0.1 0.44 10.4 0.1 1.9 2 0 0 2 2 2 0 KR domain GST_N_2 PF13409.6 KXL48842.1 - 4.5e-06 26.9 0.2 1.1e-05 25.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXL48842.1 - 0.00011 22.6 0.0 0.00018 21.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain TauD PF02668.16 KXL48843.1 - 3.6e-47 161.4 0.2 4.9e-47 161.0 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family GAS2 PF02187.17 KXL48844.1 - 9.9e-07 28.8 0.0 2.5e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain SOG2 PF10428.9 KXL48846.1 - 7 5.7 10.4 8 5.5 10.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF2470 PF10615.9 KXL48847.1 - 1.6e-21 76.7 0.1 2.3e-21 76.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) AAA PF00004.29 KXL48848.1 - 2.3e-39 134.8 0.0 3.6e-39 134.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXL48848.1 - 5e-12 45.4 0.0 1.2e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KXL48848.1 - 1e-05 26.0 0.1 0.00012 22.5 0.1 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXL48848.1 - 3e-05 24.3 0.1 0.011 16.1 0.1 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 KXL48848.1 - 3.2e-05 23.7 0.0 6.5e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KXL48848.1 - 0.00061 19.8 0.1 0.0017 18.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KXL48848.1 - 0.00084 18.6 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KXL48848.1 - 0.0017 18.5 0.0 0.0032 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KXL48848.1 - 0.0022 18.0 0.0 0.0044 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KXL48848.1 - 0.0051 16.2 0.0 0.0087 15.5 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KXL48848.1 - 0.0057 16.9 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 KXL48848.1 - 0.0065 15.9 0.0 0.19 11.1 0.0 2.4 1 1 1 2 2 2 1 Bacterial TniB protein DUF815 PF05673.13 KXL48848.1 - 0.0068 15.6 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 KXL48848.1 - 0.007 16.1 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 KXL48848.1 - 0.0095 16.1 0.0 0.034 14.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KXL48848.1 - 0.0096 16.5 0.0 0.018 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KXL48848.1 - 0.011 16.0 0.1 0.037 14.4 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_24 PF13479.6 KXL48848.1 - 0.012 15.3 0.1 0.031 14.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain DUF1517 PF07466.11 KXL48848.1 - 0.019 15.1 0.3 0.046 13.9 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) NTPase_1 PF03266.15 KXL48848.1 - 0.03 14.3 0.0 0.065 13.1 0.0 1.6 1 0 0 1 1 1 0 NTPase TsaE PF02367.17 KXL48848.1 - 0.059 13.4 0.0 0.097 12.7 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 KXL48848.1 - 0.062 13.7 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KXL48848.1 - 0.085 13.4 0.0 0.25 11.9 0.0 1.9 1 1 0 1 1 1 0 ABC transporter IPT PF01745.16 KXL48848.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase Parvo_NS1 PF01057.17 KXL48848.1 - 0.12 11.4 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 KXL48848.1 - 0.13 11.7 0.3 0.29 10.5 0.3 1.5 1 1 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 KXL48848.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 KXL48848.1 - 0.17 11.4 0.0 0.41 10.1 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region Hydin_ADK PF17213.3 KXL48848.1 - 0.25 11.6 1.1 5.9 7.1 0.1 2.6 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain Amidase PF01425.21 KXL48849.1 - 1.6e-76 258.1 0.1 2.1e-76 257.8 0.1 1.0 1 0 0 1 1 1 1 Amidase adh_short PF00106.25 KXL48850.1 - 8.2e-21 74.4 0.2 1.1e-17 64.1 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXL48850.1 - 3.3e-11 43.2 0.0 1.5e-10 41.0 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL48850.1 - 4.1e-08 33.3 0.1 6.2e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 KR domain AAA_18 PF13238.6 KXL48853.1 - 1.4e-05 25.6 0.0 0.00025 21.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain CPT PF07931.12 KXL48853.1 - 0.002 18.0 0.0 0.0033 17.3 0.0 1.3 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein PRK PF00485.18 KXL48853.1 - 0.018 14.8 0.0 0.075 12.8 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Cytidylate_kin PF02224.18 KXL48853.1 - 0.047 13.4 0.0 0.24 11.1 0.0 1.9 1 1 0 1 1 1 0 Cytidylate kinase AAA_16 PF13191.6 KXL48853.1 - 0.048 14.0 0.0 0.079 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KXL48853.1 - 0.19 11.9 0.0 0.51 10.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain KH_1 PF00013.29 KXL48854.1 - 1.6e-45 152.8 10.4 7.4e-15 54.5 0.4 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KXL48854.1 - 1.5e-12 47.2 5.1 0.0018 18.0 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KXL48854.1 - 3.8e-09 36.3 4.8 0.0091 15.9 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KXL48854.1 - 0.00026 21.0 5.8 0.68 10.1 0.1 3.4 3 0 0 3 3 3 3 NusA-like KH domain MOEP19 PF16005.5 KXL48854.1 - 0.0062 16.5 0.0 4.9 7.2 0.0 2.9 3 0 0 3 3 3 2 KH-like RNA-binding domain Aldedh PF00171.22 KXL48855.1 - 1.1e-106 357.1 0.7 1.4e-106 356.8 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KXL48855.1 - 0.022 13.8 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) TPR_12 PF13424.6 KXL48856.1 - 6e-11 42.5 38.3 0.0048 17.2 0.0 10.7 11 1 1 12 12 11 4 Tetratricopeptide repeat NACHT PF05729.12 KXL48856.1 - 1.8e-06 28.0 0.1 1.3e-05 25.2 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KXL48856.1 - 0.00013 22.2 3.6 0.00023 21.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KXL48856.1 - 0.001 19.4 1.1 0.0035 17.7 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain TPR_10 PF13374.6 KXL48856.1 - 0.0094 15.8 11.7 2.3 8.2 0.0 7.0 9 0 0 9 9 9 2 Tetratricopeptide repeat AAA PF00004.29 KXL48856.1 - 0.056 13.9 0.9 0.97 9.9 0.0 3.6 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) TPR_19 PF14559.6 KXL48856.1 - 0.45 11.1 4.7 4 8.0 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXL48856.1 - 0.49 10.6 13.2 67 4.0 0.4 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXL48856.1 - 3.2 8.0 22.0 6.7 7.0 0.1 7.9 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXL48856.1 - 3.6 8.4 5.9 1.7e+02 3.1 0.0 5.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXL48856.1 - 6 7.4 16.0 8.4 6.9 1.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Ribosomal_S8e PF01201.22 KXL48857.1 - 8.1e-55 184.7 1.1 9.3e-55 184.6 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e S10_plectin PF03501.15 KXL48858.1 - 1.8e-42 143.3 0.2 2.2e-42 143.1 0.2 1.1 1 0 0 1 1 1 1 Plectin/S10 domain SPX PF03105.19 KXL48859.1 - 2.2e-41 143.1 0.3 2e-27 97.1 0.0 2.1 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 KXL48859.1 - 1.4e-26 93.6 39.2 2.1e-26 93.0 39.2 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KXL48859.1 - 3.9e-23 82.1 48.6 1.8e-17 63.5 20.8 2.3 1 1 1 2 2 2 2 Citrate transporter Ldh_2 PF02615.14 KXL48860.1 - 2.9e-121 404.7 0.1 3.3e-121 404.5 0.1 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase zf-CSL PF05207.13 KXL48861.1 - 1.2e-21 76.2 1.2 1.8e-21 75.6 1.2 1.3 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.10 KXL48861.1 - 0.00061 19.9 0.7 0.0011 19.0 0.7 1.5 1 0 0 1 1 1 1 Zinc ribbon domain Terminase_GpA PF05876.12 KXL48861.1 - 0.002 16.8 0.1 0.002 16.8 0.1 1.1 1 0 0 1 1 1 1 Phage terminase large subunit (GpA) Frataxin_Cyay PF01491.16 KXL48862.1 - 1.7e-37 127.8 0.0 2.3e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain SLAC1 PF03595.17 KXL48863.1 - 1.4e-79 267.7 53.0 1.6e-79 267.5 53.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Peptidase_M20 PF01546.28 KXL48864.1 - 6.8e-26 91.3 0.0 1.1e-25 90.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXL48864.1 - 0.00058 19.8 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KXL48864.1 - 0.13 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 DUF5585 PF17823.1 KXL48865.1 - 0.0054 15.7 0.8 0.01 14.8 0.8 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5585) bZIP_1 PF00170.21 KXL48865.1 - 0.086 12.9 2.1 0.32 11.1 2.1 1.9 1 1 0 1 1 1 0 bZIP transcription factor Chorismate_bind PF00425.18 KXL48866.1 - 1.3e-87 293.6 0.1 1.1e-86 290.6 0.0 2.3 2 1 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 KXL48866.1 - 6.7e-29 100.9 0.0 1.7e-24 86.7 0.0 2.8 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region POR PF01558.18 KXL48866.1 - 0.05 13.7 0.0 0.091 12.8 0.0 1.4 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Stc1 PF12898.7 KXL48867.1 - 1.8e-15 57.3 6.2 2.3e-15 56.9 6.2 1.1 1 0 0 1 1 1 1 Stc1 domain Cytochrom_C PF00034.21 KXL48868.1 - 2.4e-10 41.4 0.0 3.2e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KXL48868.1 - 4.2e-07 30.2 0.4 1.3e-06 28.7 0.4 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KXL48868.1 - 0.00089 19.0 1.4 0.007 16.1 1.4 2.3 1 1 0 1 1 1 1 Cytochrome c-550 domain Cytochrome_P460 PF16694.5 KXL48868.1 - 0.055 13.8 0.3 4.5 7.6 0.2 2.0 2 0 0 2 2 2 0 Cytochrome P460 DUF4462 PF14692.6 KXL48870.1 - 0.15 11.6 0.9 0.55 9.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) adh_short PF00106.25 KXL48871.1 - 2.2e-33 115.4 0.0 2.7e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL48871.1 - 6.8e-27 94.5 0.2 8.4e-27 94.2 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL48871.1 - 1e-08 35.3 0.2 1.5e-08 34.8 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL48871.1 - 2e-05 24.2 0.1 4e-05 23.2 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXL48871.1 - 0.0028 17.6 0.6 0.011 15.6 0.6 2.1 1 1 0 1 1 1 1 NAD(P)H-binding Halo_GVPC PF05465.13 KXL48871.1 - 0.14 12.5 2.4 0.31 11.3 2.4 1.5 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat Isochorismatase PF00857.20 KXL48872.1 - 0.004 17.3 0.0 0.0051 17.0 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Acetyltransf_10 PF13673.7 KXL48873.1 - 3.1e-07 30.4 0.0 4.7e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXL48873.1 - 2.4e-06 27.9 0.0 3.8e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXL48873.1 - 1.3e-05 25.4 0.0 1.6e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KXL48873.1 - 0.0026 17.7 0.0 0.0043 17.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein DUF4695 PF15766.5 KXL48873.1 - 0.1 12.8 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4695) EnY2 PF10163.9 KXL48874.1 - 6.4e-07 29.7 1.1 9e-07 29.2 0.3 1.6 2 0 0 2 2 2 1 Transcription factor e(y)2 HEAT_2 PF13646.6 KXL48874.1 - 0.1 13.0 0.0 0.16 12.4 0.0 1.2 1 0 0 1 1 1 0 HEAT repeats MFS_1 PF07690.16 KXL48875.1 - 3.4e-19 69.0 57.5 1.5e-15 57.0 39.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HAP PF03866.13 KXL48875.1 - 0.048 13.7 0.8 0.11 12.5 0.8 1.6 1 0 0 1 1 1 0 Hydrophobic abundant protein (HAP) adh_short_C2 PF13561.6 KXL48876.1 - 1.8e-61 207.7 1.5 2.2e-61 207.4 1.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL48876.1 - 3.5e-44 150.6 1.7 4.2e-44 150.3 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL48876.1 - 0.00032 20.7 0.1 0.00051 20.0 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL48876.1 - 0.0083 15.6 0.2 0.15 11.5 0.2 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DLH PF01738.18 KXL48877.1 - 7.3e-21 74.7 0.2 8.4e-21 74.5 0.2 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KXL48877.1 - 0.093 12.2 0.0 0.82 9.1 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family RIC3 PF15361.6 KXL48878.1 - 0.0089 16.4 0.8 0.022 15.2 0.8 1.6 1 0 0 1 1 1 1 Resistance to inhibitors of cholinesterase homologue 3 Mod_r PF07200.13 KXL48878.1 - 0.03 14.4 0.2 0.046 13.8 0.2 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Sec8_exocyst PF04048.14 KXL48878.1 - 0.072 13.0 0.0 0.098 12.5 0.0 1.1 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain MscS_porin PF12795.7 KXL48878.1 - 0.14 11.7 7.1 0.22 11.0 7.1 1.3 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain FlaC_arch PF05377.11 KXL48878.1 - 0.19 12.1 1.7 0.34 11.4 1.7 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Sugarporin_N PF11471.8 KXL48878.1 - 0.67 10.0 8.9 0.47 10.4 4.5 2.1 1 1 1 2 2 2 0 Maltoporin periplasmic N-terminal extension Bromodomain PF00439.25 KXL48880.1 - 2.9e-08 33.7 0.0 1.4e-05 25.0 0.0 2.5 2 0 0 2 2 2 2 Bromodomain GCN5L1 PF06320.13 KXL48882.1 - 1.4e-18 67.1 1.8 1.7e-18 66.8 1.8 1.0 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) ZapB PF06005.12 KXL48882.1 - 0.03 14.8 2.0 0.062 13.8 2.0 1.5 1 0 0 1 1 1 0 Cell division protein ZapB Fib_alpha PF08702.10 KXL48882.1 - 0.052 13.7 0.2 0.071 13.3 0.2 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF922 PF06037.11 KXL48882.1 - 0.081 12.7 0.5 0.15 11.8 0.3 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF922) Ubiquitin_3 PF14836.6 KXL48882.1 - 0.093 12.7 0.4 0.13 12.3 0.4 1.2 1 0 0 1 1 1 0 Ubiquitin-like domain VP4_helical PF17478.2 KXL48882.1 - 0.16 11.4 0.9 0.18 11.2 0.9 1.1 1 0 0 1 1 1 0 Rotavirus VP4 helical domain Ald_Xan_dh_C2 PF02738.18 KXL48883.1 - 2.6e-209 696.3 0.4 3.6e-209 695.8 0.4 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 KXL48883.1 - 3.1e-46 157.2 0.0 6e-46 156.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 KXL48883.1 - 1.7e-33 114.8 0.1 5.3e-33 113.3 0.1 1.9 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 KXL48883.1 - 1.8e-31 108.7 0.0 6.8e-31 106.9 0.0 2.1 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 KXL48883.1 - 3.5e-29 100.6 0.0 7.3e-29 99.6 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 KXL48883.1 - 2.4e-08 33.8 1.6 3.8e-08 33.2 0.1 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF218 PF02698.17 KXL48883.1 - 0.02 14.9 0.0 0.046 13.7 0.0 1.5 1 0 0 1 1 1 0 DUF218 domain MFS_1 PF07690.16 KXL48884.1 - 7.2e-18 64.6 36.0 1.3e-14 53.9 16.4 2.4 3 0 0 3 3 3 2 Major Facilitator Superfamily Adeno_E3 PF06040.11 KXL48884.1 - 6.9 6.9 6.6 1.3 9.2 1.6 2.3 2 0 0 2 2 2 0 Adenovirus E3 protein Glyco_hydro_30 PF02055.16 KXL48885.1 - 2.4e-20 72.8 0.1 5.5e-20 71.6 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 KXL48885.1 - 9.4e-05 22.6 0.0 0.00022 21.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Diphthamide_syn PF01866.17 KXL48886.1 - 4.9e-118 394.0 0.0 6.2e-118 393.6 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein SKN1 PF03935.15 KXL48887.1 - 1.5e-218 726.3 0.6 1.7e-218 726.1 0.6 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Alpha-L-AF_C PF06964.12 KXL48888.1 - 1.9e-28 99.7 0.2 3.2e-28 99.0 0.2 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_44 PF12891.7 KXL48888.1 - 0.023 14.7 0.1 0.049 13.6 0.1 1.6 1 0 0 1 1 1 0 Glycoside hydrolase family 44 Sugar_tr PF00083.24 KXL48889.1 - 6.9e-102 341.6 19.6 7.8e-102 341.4 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL48889.1 - 2.1e-27 96.0 26.3 2e-26 92.8 17.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MatC_N PF07158.11 KXL48889.1 - 0.0027 17.8 4.6 0.008 16.2 2.8 2.2 2 0 0 2 2 2 1 Dicarboxylate carrier protein MatC N-terminus DUF2530 PF10745.9 KXL48889.1 - 0.029 14.6 0.5 0.14 12.4 0.5 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) FMN_dh PF01070.18 KXL48890.1 - 1.1e-116 389.7 0.0 1.3e-116 389.5 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KXL48890.1 - 2.5e-07 30.0 0.1 4.7e-06 25.8 0.0 2.3 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KXL48890.1 - 1.9e-06 27.3 0.1 9.7e-06 24.9 0.0 1.9 2 0 0 2 2 2 1 Conserved region in glutamate synthase His_biosynth PF00977.21 KXL48890.1 - 0.0016 17.9 0.1 0.022 14.3 0.0 2.3 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 KXL48890.1 - 0.05 12.9 0.1 1.5 8.0 0.0 2.2 1 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG TruB_C PF09142.11 KXL48890.1 - 0.14 11.9 0.1 0.29 11.0 0.1 1.5 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal DHO_dh PF01180.21 KXL48890.1 - 0.14 11.3 0.1 0.34 10.1 0.0 1.5 1 1 0 2 2 2 0 Dihydroorotate dehydrogenase zf-BED PF02892.15 KXL48891.1 - 0.28 11.2 10.6 0.46 10.5 2.2 2.5 2 0 0 2 2 2 0 BED zinc finger zinc_ribbon_4 PF13717.6 KXL48891.1 - 0.6 10.1 4.3 3.6 7.6 1.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain BIR PF00653.21 KXL48891.1 - 0.7 10.6 3.9 1.7 9.4 0.6 2.4 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain Transp_cyt_pur PF02133.15 KXL48892.1 - 3e-21 75.7 38.8 5.3e-21 74.9 38.8 1.4 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF5453 PF17534.2 KXL48892.1 - 0.19 11.7 5.4 0.056 13.4 1.9 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5453) F-box-like PF12937.7 KXL48894.1 - 1.5e-06 27.9 0.1 3.3e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like Glyco_hydro_16 PF00722.21 KXL48897.1 - 2.6e-47 160.6 1.9 4.1e-47 159.9 1.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 KXL48897.1 - 1.5 9.3 18.6 0.084 13.4 13.0 1.8 2 0 0 2 2 2 0 Chitin recognition protein Ribosomal_S21e PF01249.18 KXL48898.1 - 7.6e-43 144.5 0.0 8.4e-43 144.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e SH3_9 PF14604.6 KXL48900.1 - 7e-12 45.0 0.1 1.5e-11 44.0 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXL48900.1 - 6.4e-10 38.5 0.7 1.6e-09 37.2 0.0 2.1 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KXL48900.1 - 0.004 16.8 1.6 0.0049 16.5 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain Sugar_tr PF00083.24 KXL48901.1 - 1.3e-91 307.8 23.1 1.4e-91 307.6 23.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL48901.1 - 1.9e-30 106.0 34.7 1.7e-17 63.4 17.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 KXL48901.1 - 0.00014 20.5 2.3 0.034 12.6 0.6 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector DUF3792 PF12670.7 KXL48901.1 - 0.93 9.7 26.8 0.62 10.3 9.6 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3792) Glutaredoxin PF00462.24 KXL48902.1 - 1.4e-15 57.3 0.0 2.7e-15 56.3 0.0 1.5 2 0 0 2 2 2 1 Glutaredoxin Flavoprotein PF02441.19 KXL48903.1 - 9.5e-48 161.9 0.0 1.1e-47 161.7 0.0 1.0 1 0 0 1 1 1 1 Flavoprotein DUF4148 PF13663.6 KXL48903.1 - 0.07 13.3 1.1 0.21 11.8 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4148) Neurensin PF14927.6 KXL48904.1 - 0.00044 20.0 0.1 0.00044 20.0 0.1 2.7 2 2 1 3 3 3 1 Neurensin DUF3007 PF11460.8 KXL48904.1 - 0.076 13.3 0.3 0.076 13.3 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) Insulin_TMD PF17870.1 KXL48904.1 - 1.3 9.1 4.5 2.4 8.3 0.4 2.4 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment 4F5 PF04419.14 KXL48906.1 - 3.1e-09 37.5 17.2 3.1e-09 37.5 17.2 1.7 1 1 1 2 2 2 1 4F5 protein family OAD_gamma PF04277.13 KXL48906.1 - 0.068 13.8 3.8 0.068 13.8 3.8 1.0 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Phage_Gp23 PF10669.9 KXL48906.1 - 1.1 9.6 6.7 1.2 9.5 6.7 1.0 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Motile_Sperm PF00635.26 KXL48907.1 - 5.3e-25 87.4 0.1 9.7e-25 86.5 0.1 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain DUF737 PF05300.11 KXL48907.1 - 0.0074 16.7 0.3 0.0083 16.5 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF737) UBX PF00789.20 KXL48908.1 - 4.9e-08 33.1 0.0 9.7e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBA PF00627.31 KXL48908.1 - 0.00015 21.5 2.8 0.00018 21.3 0.1 2.6 3 0 0 3 3 3 1 UBA/TS-N domain RR_TM4-6 PF06459.12 KXL48908.1 - 0.0061 16.4 14.2 0.0091 15.9 14.2 1.2 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 DUF2757 PF10955.8 KXL48908.1 - 0.02 15.1 0.0 0.052 13.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) zf-C2H2_2 PF12756.7 KXL48908.1 - 0.086 13.2 0.3 0.44 10.9 0.0 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) SOBP PF15279.6 KXL48908.1 - 0.46 11.0 6.8 0.58 10.7 6.8 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein CDC45 PF02724.14 KXL48908.1 - 0.68 8.1 12.0 0.86 7.8 12.0 1.1 1 0 0 1 1 1 0 CDC45-like protein V_ATPase_I PF01496.19 KXL48908.1 - 1.6 6.6 4.8 1.5 6.6 4.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PIEZO PF15917.5 KXL48908.1 - 2 7.9 9.5 2.8 7.3 9.5 1.2 1 0 0 1 1 1 0 Piezo UPF0242 PF06785.11 KXL48908.1 - 2.6 8.1 11.5 3.9 7.5 11.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Borrelia_P83 PF05262.11 KXL48908.1 - 3.9 5.8 16.2 4.7 5.6 16.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein PA26 PF04636.13 KXL48908.1 - 4.2 6.2 6.5 5.1 5.9 6.5 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Atg14 PF10186.9 KXL48908.1 - 5.6 6.0 11.0 4.4 6.3 9.8 1.5 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ALMT PF11744.8 KXL48908.1 - 5.7 5.7 7.6 7.7 5.2 7.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Hid1 PF12722.7 KXL48908.1 - 9.3 4.2 7.1 9 4.3 7.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ufd2P_core PF10408.9 KXL48909.1 - 1.9e-207 690.8 12.6 2.7e-207 690.3 12.6 1.2 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KXL48909.1 - 4e-27 94.2 0.7 1.2e-26 92.7 0.7 1.8 1 0 0 1 1 1 1 U-box domain Mad3_BUB1_I PF08311.12 KXL48909.1 - 0.0039 17.2 1.0 0.97 9.4 0.1 3.4 3 0 0 3 3 3 1 Mad3/BUB1 homology region 1 Prion PF00377.18 KXL48909.1 - 0.05 13.5 0.5 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 Prion/Doppel alpha-helical domain ECSIT PF06239.11 KXL48910.1 - 0.025 13.7 0.3 0.026 13.7 0.3 1.1 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway REV PF00424.18 KXL48911.1 - 0.67 10.0 8.5 0.73 9.9 8.5 1.2 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Aim19 PF10315.9 KXL48912.1 - 1.1e-05 25.7 0.0 1.4e-05 25.4 0.0 1.4 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 19 DUF1977 PF09320.11 KXL48913.1 - 1.1e-31 109.2 0.1 2e-31 108.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 KXL48913.1 - 1.9e-20 72.7 0.2 3.1e-20 72.1 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain Aldo_ket_red PF00248.21 KXL48914.1 - 1.4e-48 165.6 0.0 5.9e-48 163.6 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family DAO PF01266.24 KXL48915.1 - 3.1e-50 171.8 0.0 5.6e-50 170.9 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KXL48915.1 - 1.1e-44 151.3 0.0 2e-44 150.5 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 KXL48915.1 - 8.9e-08 31.6 0.2 2.2e-07 30.3 0.2 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXL48915.1 - 0.00025 20.4 0.0 0.00066 19.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXL48915.1 - 0.001 18.5 0.1 0.0017 17.8 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXL48915.1 - 0.0068 16.6 0.1 0.025 14.8 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KXL48915.1 - 0.019 14.1 0.4 0.61 9.1 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 KXL48915.1 - 0.026 14.4 0.1 0.06 13.2 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 KXL48915.1 - 0.071 12.4 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXL48915.1 - 0.096 13.3 0.1 0.37 11.4 0.1 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXL48915.1 - 0.15 11.3 0.1 0.29 10.3 0.1 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KXL48915.1 - 0.24 10.1 1.3 0.27 9.9 0.4 1.5 2 0 0 2 2 2 0 HI0933-like protein 60KD_IMP PF02096.20 KXL48916.1 - 0.043 13.7 1.0 0.2 11.6 1.0 2.0 1 1 0 1 1 1 0 60Kd inner membrane protein FA_desaturase PF00487.24 KXL48917.1 - 1.3e-22 80.9 13.4 1.9e-22 80.3 13.4 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 KXL48917.1 - 5.6e-17 60.9 0.3 1.1e-16 60.0 0.3 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Fe-ADH PF00465.19 KXL48918.1 - 1.4e-22 80.1 0.0 1.9e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase BRO1 PF03097.18 KXL48919.1 - 1.9e-120 402.3 0.1 1.9e-120 402.3 0.1 1.7 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KXL48919.1 - 5.3e-78 262.3 12.2 5.3e-78 262.3 12.2 2.1 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV Flagellin_C PF00700.21 KXL48919.1 - 0.53 10.7 4.2 11 6.5 2.9 2.9 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region Fungal_trans PF04082.18 KXL48920.1 - 9.7e-26 90.4 0.0 1.7e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL48920.1 - 3.4e-08 33.5 9.3 8.7e-08 32.2 9.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_2 PF07992.14 KXL48921.1 - 7.3e-63 212.5 0.1 9.9e-63 212.1 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KXL48921.1 - 8.2e-33 113.0 0.2 2.1e-32 111.6 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KXL48921.1 - 1.8e-18 66.9 0.7 2.5e-17 63.2 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXL48921.1 - 7.5e-18 64.8 0.1 1e-17 64.4 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXL48921.1 - 2.2e-07 30.4 0.0 3.4e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 KXL48921.1 - 0.00034 20.0 0.5 0.58 9.4 0.2 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KXL48921.1 - 0.0014 18.1 0.0 0.003 17.0 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 KXL48921.1 - 0.0034 16.5 0.2 0.057 12.5 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KXL48921.1 - 0.051 12.7 1.7 0.54 9.3 1.1 2.3 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 KXL48921.1 - 0.062 12.0 0.8 4.8 5.8 0.5 2.9 3 0 0 3 3 3 0 HI0933-like protein Eno-Rase_NADH_b PF12242.8 KXL48921.1 - 0.087 12.6 0.6 1.7 8.5 0.1 3.1 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DAO PF01266.24 KXL48921.1 - 0.55 9.8 2.5 0.93 9.0 0.0 2.5 2 1 0 3 3 3 0 FAD dependent oxidoreductase Ribosom_S12_S23 PF00164.25 KXL48922.1 - 4.9e-51 171.1 0.5 6.1e-51 170.8 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Formyl_trans_N PF00551.19 KXL48923.1 - 5.9e-27 94.6 0.0 7.4e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase ADH_N PF08240.12 KXL48924.1 - 0.00022 21.1 0.0 0.00044 20.1 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXL48924.1 - 0.0099 15.9 0.1 0.017 15.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NCBP3 PF10309.9 KXL48925.1 - 5.9e-14 51.7 0.0 9.4e-14 51.0 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 Polysacc_deac_1 PF01522.21 KXL48926.1 - 6.2e-17 61.7 0.0 1e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KXL48926.1 - 1.6e-10 41.0 0.0 2.6e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 KXL48926.1 - 0.00088 17.8 0.1 0.0012 17.3 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2194) Glyco_hydro_57 PF03065.15 KXL48926.1 - 0.031 13.5 0.0 0.055 12.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 AAT PF03417.16 KXL48927.1 - 2e-27 96.4 0.0 2.4e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Fungal_lectin PF07938.12 KXL48928.1 - 2.5e-08 33.7 2.6 0.0026 17.2 0.4 2.2 1 1 0 2 2 2 2 Fungal fucose-specific lectin Med5 PF08689.10 KXL48929.1 - 2.3e-77 260.9 0.0 5.9e-76 256.2 0.0 2.2 1 1 0 1 1 1 1 Mediator complex subunit Med5 adh_short_C2 PF13561.6 KXL48930.1 - 2.3e-42 145.2 0.8 2.9e-42 144.9 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL48930.1 - 3.2e-37 127.9 0.2 4.1e-37 127.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL48930.1 - 1.2e-16 61.1 0.3 1.8e-16 60.6 0.3 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXL48930.1 - 0.00068 18.9 0.1 0.00091 18.4 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KXL48930.1 - 0.11 12.0 0.1 0.65 9.4 0.1 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Nfu_N PF08712.11 KXL48930.1 - 0.17 12.0 0.0 0.51 10.4 0.0 1.8 2 0 0 2 2 2 0 Scaffold protein Nfu/NifU N terminal Aldo_ket_red PF00248.21 KXL48932.1 - 7.4e-42 143.5 0.0 5.7e-40 137.3 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Ribosomal_L17 PF01196.19 KXL48933.1 - 3.3e-34 117.7 0.1 7.4e-34 116.5 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L17 Molybdopterin_N PF18364.1 KXL48933.1 - 0.038 14.0 0.0 0.069 13.2 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin oxidoreductase N-terminal domain Mrpl_C PF18502.1 KXL48933.1 - 0.065 13.5 0.1 0.31 11.3 0.0 1.9 2 0 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain TMP_2 PF06791.13 KXL48933.1 - 0.086 12.5 0.2 0.16 11.6 0.2 1.3 1 0 0 1 1 1 0 Prophage tail length tape measure protein AIM5 PF17050.5 KXL48934.1 - 8.4e-18 64.9 0.7 1.1e-17 64.6 0.7 1.2 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 Pkinase PF00069.25 KXL48935.1 - 5.2e-27 94.9 0.0 6.7e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL48935.1 - 1.3e-14 54.1 0.0 1.7e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXL48935.1 - 5.7e-07 28.6 0.0 5.7e-07 28.6 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Peptidase_M44 PF03410.13 KXL48935.1 - 0.15 10.6 0.0 0.21 10.1 0.0 1.1 1 0 0 1 1 1 0 Metallopeptidase from vaccinia pox EMP24_GP25L PF01105.24 KXL48937.1 - 2.9e-48 164.2 0.2 3.4e-48 164.0 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Peptidase_M28 PF04389.17 KXL48937.1 - 0.14 11.8 0.2 8 6.1 0.0 2.1 2 0 0 2 2 2 0 Peptidase family M28 Ion_trans PF00520.31 KXL48938.1 - 4.1e-11 42.6 1.9 5.5e-11 42.2 1.9 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KXL48938.1 - 0.0059 15.3 0.5 0.0082 14.9 0.5 1.3 1 0 0 1 1 1 1 Polycystin cation channel FlaC_arch PF05377.11 KXL48938.1 - 0.014 15.8 3.0 0.027 14.9 3.0 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) bZIP_1 PF00170.21 KXL48938.1 - 0.018 15.1 2.3 0.033 14.3 2.3 1.4 1 0 0 1 1 1 0 bZIP transcription factor HAP1_N PF04849.13 KXL48938.1 - 0.02 14.1 1.1 0.028 13.6 1.1 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region HALZ PF02183.18 KXL48938.1 - 0.057 13.7 0.9 0.095 12.9 0.9 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper adh_short_C2 PF13561.6 KXL48939.1 - 6.6e-54 182.9 0.0 8.1e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL48939.1 - 1.6e-40 138.7 0.0 1.9e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL48939.1 - 2.5e-09 37.3 0.0 3.7e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 KR domain AAA PF00004.29 KXL48940.1 - 2.2e-16 60.5 0.0 5e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXL48940.1 - 2.3e-05 24.7 0.6 0.0049 17.1 0.0 2.8 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KXL48940.1 - 6.2e-05 23.4 0.7 0.00088 19.7 0.7 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KXL48940.1 - 0.0046 17.0 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Vps36_ESCRT-II PF11605.8 KXL48940.1 - 0.018 15.2 0.0 0.041 14.1 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 RuvB_N PF05496.12 KXL48940.1 - 0.039 13.7 0.0 0.085 12.6 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 KXL48940.1 - 0.083 12.6 0.0 0.27 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KXL48940.1 - 0.12 12.8 0.0 0.58 10.5 0.0 2.1 2 1 0 2 2 2 0 AAA domain TrbC PF04956.13 KXL48942.1 - 0.25 11.6 0.2 0.25 11.6 0.2 2.2 3 0 0 3 3 3 0 TrbC/VIRB2 family ALAD PF00490.21 KXL48943.1 - 2.4e-121 404.8 0.0 3e-121 404.5 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase S36_mt PF10937.8 KXL48945.1 - 1.7e-43 148.8 2.6 2.7e-43 148.2 2.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial Med18 PF09637.10 KXL48946.1 - 5.3e-28 98.5 0.0 7.5e-26 91.5 0.0 2.0 1 1 0 1 1 1 1 Med18 protein Sugar_tr PF00083.24 KXL48947.1 - 1.1e-137 459.6 27.2 1.3e-137 459.4 27.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL48947.1 - 7.2e-22 77.8 37.2 3.1e-12 46.1 14.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 KXL48947.1 - 0.96 9.7 8.2 0.7 10.2 4.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) UPF0715 PF17094.5 KXL48947.1 - 3.8 8.1 8.2 0.92 10.1 4.1 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0715) Sulfatase PF00884.23 KXL48949.1 - 7.6e-62 209.5 0.9 1.1e-61 209.0 0.9 1.2 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 KXL48949.1 - 3.2e-05 24.1 0.2 8e-05 22.8 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 KXL48949.1 - 0.013 15.1 0.3 0.11 12.1 0.4 2.0 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Ndc1_Nup PF09531.10 KXL48950.1 - 2.3e-145 485.7 0.0 2.9e-145 485.4 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Syntaxin_2 PF14523.6 KXL48951.1 - 3.8e-23 81.8 0.3 3.8e-23 81.8 0.3 3.0 2 1 1 3 3 3 1 Syntaxin-like protein SNARE PF05739.19 KXL48951.1 - 4.1e-10 39.5 0.6 4.1e-10 39.5 0.6 2.3 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.25 KXL48951.1 - 0.00018 21.3 17.1 0.00082 19.1 17.1 2.0 1 1 0 1 1 1 1 Syntaxin DUF948 PF06103.11 KXL48951.1 - 0.0028 17.9 1.1 0.58 10.5 0.0 2.6 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF948) T7SS_ESX_EspC PF10824.8 KXL48951.1 - 0.026 15.0 2.7 0.13 12.8 0.2 2.6 2 1 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm Synaptobrevin PF00957.21 KXL48951.1 - 0.066 13.0 0.3 0.69 9.7 0.2 2.3 2 0 0 2 2 2 0 Synaptobrevin DUF1664 PF07889.12 KXL48951.1 - 0.074 13.1 7.7 6.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Nre_C PF04895.12 KXL48951.1 - 0.17 11.8 0.0 0.17 11.8 0.0 2.6 3 0 0 3 3 3 0 Archaeal Nre, C-terminal YtxH PF12732.7 KXL48951.1 - 0.28 11.8 1.8 1.7 9.3 0.0 2.8 2 1 0 2 2 2 0 YtxH-like protein DUF4446 PF14584.6 KXL48951.1 - 1.2 9.1 4.5 15 5.6 2.1 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF4446) DUF883 PF05957.13 KXL48951.1 - 1.6 9.4 20.7 1.1 9.9 0.2 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Prominin PF05478.11 KXL48951.1 - 2.7 5.8 7.7 0.89 7.4 2.8 2.0 1 1 0 2 2 2 0 Prominin FapA PF03961.13 KXL48951.1 - 3.1 6.3 11.0 0.48 9.0 0.0 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A Tcp11 PF05794.13 KXL48953.1 - 1.6e-97 327.4 5.6 1.6e-97 327.4 5.6 2.0 2 0 0 2 2 2 1 T-complex protein 11 CIAPIN1 PF05093.13 KXL48954.1 - 1.2e-39 134.9 3.1 2.3e-39 133.9 3.1 1.5 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 KXL48954.1 - 1.5e-36 125.6 0.0 2.2e-36 125.0 0.0 1.3 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus Nucleoporin_C PF03177.14 KXL48955.1 - 5.1e-119 398.7 15.5 6.3e-119 398.4 15.5 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 KXL48955.1 - 4e-42 144.5 0.0 5.1e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like Pkinase PF00069.25 KXL48956.1 - 7.7e-12 45.1 0.0 1.2e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Cnd1 PF12717.7 KXL48956.1 - 9e-08 32.3 0.0 1.4e-06 28.4 0.0 2.3 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Pkinase_Tyr PF07714.17 KXL48956.1 - 1.3e-07 31.2 0.0 2.1e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 KXL48956.1 - 1.8e-06 27.7 2.9 0.087 13.1 0.0 5.0 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 KXL48956.1 - 0.00024 21.4 3.7 0.003 17.9 0.3 3.0 2 1 2 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 KXL48956.1 - 0.00037 20.9 0.1 0.67 10.5 0.1 3.1 2 0 0 2 2 2 2 HEAT-like repeat Kinase-like PF14531.6 KXL48956.1 - 0.0017 17.7 0.0 0.0027 17.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like CLASP_N PF12348.8 KXL48956.1 - 0.063 12.8 0.0 1.3 8.5 0.0 2.2 1 1 1 2 2 2 0 CLASP N terminal Adaptin_N PF01602.20 KXL48956.1 - 0.063 11.8 0.0 0.69 8.4 0.0 2.1 1 1 1 2 2 2 0 Adaptin N terminal region PHD PF00628.29 KXL48957.1 - 4.2e-07 29.7 5.4 7.8e-07 28.9 5.4 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KXL48957.1 - 0.00061 19.3 4.0 0.0012 18.3 4.0 1.5 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 KXL48957.1 - 0.0025 17.7 3.7 0.0025 17.7 3.7 2.0 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 KXL48957.1 - 0.0088 16.0 3.4 0.019 14.9 3.4 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-HC5HC2H_2 PF13832.6 KXL48957.1 - 0.03 14.5 1.6 0.054 13.7 1.6 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain FYVE_2 PF02318.16 KXL48957.1 - 0.041 14.1 2.5 0.082 13.1 2.5 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger C1_2 PF03107.16 KXL48957.1 - 0.26 11.7 3.7 0.54 10.6 1.5 2.2 2 0 0 2 2 2 0 C1 domain NACHT PF05729.12 KXL48958.1 - 3.2e-13 49.9 0.2 1.3e-12 47.9 0.0 2.2 2 0 0 2 2 1 1 NACHT domain Ank_2 PF12796.7 KXL48958.1 - 1.6e-11 44.6 0.0 0.00042 20.8 0.0 4.4 3 1 2 5 5 5 2 Ankyrin repeats (3 copies) AAA_16 PF13191.6 KXL48958.1 - 5e-10 40.0 0.2 1.8e-09 38.2 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain Ank_4 PF13637.6 KXL48958.1 - 9.3e-09 35.7 0.1 0.001 19.6 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXL48958.1 - 4.7e-08 32.7 0.2 16 6.5 0.0 6.7 6 0 0 6 6 6 0 Ankyrin repeat AAA_22 PF13401.6 KXL48958.1 - 1e-07 32.3 0.0 4.1e-07 30.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain Adeno_IVa2 PF02456.15 KXL48958.1 - 8.2e-05 21.6 0.0 0.00015 20.7 0.0 1.3 1 0 0 1 1 1 1 Adenovirus IVa2 protein NB-ARC PF00931.22 KXL48958.1 - 0.0012 18.1 0.0 0.003 16.8 0.0 1.6 1 1 0 1 1 1 1 NB-ARC domain ATPase_2 PF01637.18 KXL48958.1 - 0.0017 18.3 0.0 0.0047 16.9 0.0 1.7 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 KXL48958.1 - 0.0036 16.6 0.0 2.5 7.3 0.2 2.3 1 1 1 2 2 2 2 KAP family P-loop domain TniB PF05621.11 KXL48958.1 - 0.0085 15.5 0.0 0.26 10.7 0.0 2.5 2 0 0 2 2 2 1 Bacterial TniB protein Ank_5 PF13857.6 KXL48958.1 - 0.0088 16.3 0.1 15 6.1 0.0 4.4 5 0 0 5 5 4 0 Ankyrin repeats (many copies) AAA PF00004.29 KXL48958.1 - 0.013 15.9 0.0 0.09 13.2 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KXL48958.1 - 0.032 14.3 0.1 0.48 10.5 0.0 2.6 2 1 1 3 3 2 0 AAA domain ABC_tran PF00005.27 KXL48958.1 - 0.16 12.5 0.0 0.38 11.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 KXL48958.1 - 0.19 12.2 0.0 0.41 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain F-box PF00646.33 KXL48959.1 - 1.1e-05 25.1 0.1 2.1e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXL48959.1 - 0.00093 19.1 0.2 0.0018 18.1 0.2 1.5 1 0 0 1 1 1 1 F-box-like Gly-zipper_Omp PF13488.6 KXL48960.1 - 0.029 14.4 9.8 0.029 14.4 9.8 1.8 2 0 0 2 2 2 0 Glycine zipper Rick_17kDa_Anti PF05433.15 KXL48960.1 - 0.072 13.0 16.3 0.49 10.3 4.6 2.2 1 1 2 3 3 3 0 Glycine zipper 2TM domain Corona_nucleoca PF00937.18 KXL48960.1 - 1.1 8.2 12.8 1.1 8.2 11.7 1.4 1 1 0 1 1 1 0 Coronavirus nucleocapsid protein Sugar_tr PF00083.24 KXL48961.1 - 9.7e-94 314.8 14.5 1.2e-93 314.5 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL48961.1 - 1.2e-19 70.5 25.1 2.7e-19 69.3 24.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Pyr_redox_3 PF13738.6 KXL48962.1 - 2.2e-16 60.0 0.0 3.5e-15 56.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXL48962.1 - 3.2e-16 58.8 0.0 5.7e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXL48962.1 - 7.2e-10 38.6 0.0 2.2e-08 33.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXL48962.1 - 2.5e-07 30.2 0.2 1.1e-05 24.7 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXL48962.1 - 2.6e-07 30.8 0.0 1.3e-06 28.6 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KXL48962.1 - 5.2e-05 23.3 0.2 0.9 9.5 0.2 4.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KXL48962.1 - 0.0061 15.8 0.1 0.023 13.9 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 KXL48962.1 - 0.023 13.8 0.0 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KXL48962.1 - 0.051 14.1 0.1 2.3 8.9 0.1 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXL48962.1 - 0.14 11.4 0.6 0.56 9.4 0.1 2.0 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 KXL48962.1 - 0.22 10.2 0.1 1.5 7.5 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.24 KXL48962.1 - 0.62 9.6 2.5 5.3 6.5 0.2 2.9 1 1 2 3 3 3 0 FAD dependent oxidoreductase ATG13 PF10033.9 KXL48963.1 - 4.8e-58 196.7 0.0 6.3e-58 196.3 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 13 PAP1 PF08601.10 KXL48964.1 - 7.5e-48 164.1 66.4 3e-23 83.2 0.3 5.1 3 1 2 5 5 5 3 Transcription factor PAP1 bZIP_1 PF00170.21 KXL48964.1 - 1.4e-07 31.5 8.5 2.8e-07 30.5 8.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor SHE3 PF17078.5 KXL48964.1 - 0.0059 16.3 5.1 0.011 15.4 5.1 1.4 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 Mg_chelatase_C PF13335.6 KXL48964.1 - 0.033 14.8 0.6 0.087 13.5 0.6 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal bZIP_Maf PF03131.17 KXL48964.1 - 0.2 12.2 7.3 0.55 10.8 7.3 1.8 1 0 0 1 1 1 0 bZIP Maf transcription factor CENP-W PF15510.6 KXL48964.1 - 0.32 11.2 2.4 10 6.4 0.2 2.9 3 0 0 3 3 3 0 CENP-W protein TUDOR PF00567.24 KXL48966.1 - 3.9e-07 30.1 0.1 8.2e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 Tudor domain SMN PF06003.12 KXL48966.1 - 0.0015 17.9 1.4 0.0015 17.9 1.4 2.5 1 1 2 3 3 3 1 Survival motor neuron protein (SMN) DUF1325 PF07039.11 KXL48966.1 - 0.0018 18.3 0.2 0.0044 17.1 0.2 1.6 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 KXL48966.1 - 0.0046 16.8 0.4 0.025 14.4 0.4 2.2 2 1 0 2 2 2 1 DNA repair protein Crb2 Tudor domain LBR_tudor PF09465.10 KXL48966.1 - 0.0075 16.1 0.2 0.012 15.4 0.2 1.3 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain SAWADEE PF16719.5 KXL48966.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 SAWADEE domain DUF1502 PF07397.11 KXL48967.1 - 0.19 11.6 4.0 0.2 11.5 0.1 2.6 2 1 0 2 2 2 0 Repeat of unknown function (DUF1502) Ion_trans_2 PF07885.16 KXL48969.1 - 2.6e-26 91.4 28.1 2.9e-14 52.8 9.2 3.2 3 0 0 3 3 3 2 Ion channel IRK PF01007.20 KXL48969.1 - 0.15 11.8 4.6 6.3 6.6 0.2 3.1 2 1 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain MASE5 PF17178.4 KXL48970.1 - 3.5 7.4 12.5 0.082 12.7 3.4 2.7 4 0 0 4 4 4 0 Membrane-associated sensor Cupin_5 PF06172.11 KXL48971.1 - 9.9e-38 129.5 0.0 1.3e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) PNP_UDP_1 PF01048.20 KXL48972.1 - 2.1e-42 145.0 0.1 2.6e-42 144.7 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily adh_short PF00106.25 KXL48973.1 - 5.6e-33 114.0 0.0 3.2e-25 88.7 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXL48973.1 - 4.1e-15 56.0 0.0 4.2e-11 42.9 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL48973.1 - 1.1e-08 35.2 0.0 1.6e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL48973.1 - 0.0019 17.7 0.0 0.004 16.6 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXL48973.1 - 0.013 14.5 0.0 0.022 13.8 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXL48973.1 - 0.037 13.4 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KXL48973.1 - 0.049 13.5 0.0 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXL48973.1 - 0.2 10.7 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 2-Hacid_dh_C PF02826.19 KXL48974.1 - 4.5e-41 140.2 0.0 1.3e-40 138.7 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXL48974.1 - 2.9e-22 78.8 0.0 3.6e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 KXL48974.1 - 0.022 14.8 1.5 0.065 13.3 0.4 2.1 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 KXL48974.1 - 0.063 13.8 0.0 0.17 12.4 0.0 1.7 2 0 0 2 2 2 0 XdhC Rossmann domain adh_short_C2 PF13561.6 KXL48975.1 - 9.8e-55 185.7 0.1 1.3e-54 185.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL48975.1 - 3.3e-45 154.0 0.1 4.2e-45 153.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 KXL48975.1 - 0.00017 21.2 0.1 0.0011 18.5 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXL48975.1 - 0.0004 20.3 0.3 0.0017 18.3 0.1 1.9 2 0 0 2 2 2 1 KR domain HEAT PF02985.22 KXL48977.1 - 1.2e-14 53.2 4.8 0.00031 20.8 0.1 8.6 9 0 0 9 9 7 3 HEAT repeat HEAT_EZ PF13513.6 KXL48977.1 - 3.1e-14 53.1 9.3 4.6e-06 27.0 0.2 8.8 9 1 1 10 10 8 3 HEAT-like repeat HEAT_2 PF13646.6 KXL48977.1 - 3.6e-14 52.9 4.5 0.0092 16.3 0.1 8.3 5 4 1 7 7 7 4 HEAT repeats IBN_N PF03810.19 KXL48977.1 - 6.6e-14 51.6 0.3 6.1e-11 42.1 0.1 3.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain UME PF08064.13 KXL48977.1 - 9.5e-07 28.7 0.4 0.042 13.8 0.2 4.7 4 1 1 5 5 4 2 UME (NUC010) domain RIX1 PF08167.12 KXL48977.1 - 1.4e-06 28.2 0.0 1 9.1 0.0 5.5 3 2 0 4 4 4 1 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.7 KXL48977.1 - 1.7e-05 25.3 0.7 2.5 8.7 0.0 5.5 6 0 0 6 6 5 1 Vacuolar 14 Fab1-binding region IFRD PF05004.13 KXL48977.1 - 2.1e-05 23.8 7.7 0.018 14.1 0.4 4.5 4 2 1 5 5 5 2 Interferon-related developmental regulator (IFRD) Adaptin_N PF01602.20 KXL48977.1 - 2.5e-05 23.0 0.1 0.0022 16.6 0.0 3.0 3 1 0 3 3 3 1 Adaptin N terminal region Arm PF00514.23 KXL48977.1 - 3.8e-05 23.6 2.2 6.5 7.0 0.1 6.4 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 KXL48977.1 - 0.00017 21.7 4.4 1.2 9.1 0.5 4.7 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 KXL48977.1 - 0.00048 19.4 0.0 0.0066 15.6 0.0 3.0 2 1 1 3 3 3 1 RNAPII transcription regulator C-terminal NUC173 PF08161.12 KXL48977.1 - 0.00058 19.6 0.7 3.8 7.1 0.0 4.2 4 0 0 4 4 4 2 NUC173 domain RTP1_C1 PF10363.9 KXL48977.1 - 0.0019 18.3 1.0 4.8 7.4 0.0 5.0 3 2 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 V-ATPase_H_N PF03224.14 KXL48977.1 - 0.0058 16.0 0.6 8.8 5.5 0.0 3.9 3 1 0 3 3 3 1 V-ATPase subunit H Tti2 PF10521.9 KXL48977.1 - 0.019 14.5 0.1 2.8 7.4 0.0 3.3 3 0 0 3 3 3 0 Tti2 family DUF1759 PF03564.15 KXL48977.1 - 0.091 12.7 0.1 0.42 10.5 0.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) Cohesin_HEAT PF12765.7 KXL48977.1 - 0.12 12.6 0.2 0.74 10.2 0.0 2.5 3 0 0 3 3 2 0 HEAT repeat associated with sister chromatid cohesion His_Phos_2 PF00328.22 KXL48978.1 - 2.3e-16 60.1 0.0 1.5e-13 50.9 0.0 2.1 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Cellulase PF00150.18 KXL48979.1 - 2.1e-16 60.2 1.1 2.1e-16 60.2 1.1 1.8 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF3357 PF11837.8 KXL48979.1 - 0.022 15.2 0.0 0.055 13.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DUF2116 PF09889.9 KXL48979.1 - 0.072 13.1 0.1 0.19 11.7 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) ETRAMP PF09716.10 KXL48979.1 - 0.091 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) GST_C_4 PF14834.6 KXL48979.1 - 0.094 13.1 0.0 1.9 8.9 0.0 2.4 1 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain ParA PF10609.9 KXL48980.1 - 4.1e-95 317.9 0.1 4.8e-95 317.7 0.1 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KXL48980.1 - 8.9e-13 48.4 0.0 1.3e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KXL48980.1 - 1.7e-08 34.6 1.9 5.4e-07 29.7 1.9 2.2 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 KXL48980.1 - 1.6e-05 24.3 0.0 2.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.6 KXL48980.1 - 0.00023 20.8 0.0 0.00038 20.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 KXL48980.1 - 0.0027 17.2 0.0 0.17 11.3 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 KXL48980.1 - 0.0045 16.2 1.4 0.032 13.4 0.7 2.2 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_26 PF13500.6 KXL48980.1 - 0.033 14.0 0.7 6.2 6.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain CLP1_P PF16575.5 KXL48980.1 - 0.088 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Cutinase PF01083.22 KXL48981.1 - 2.7e-39 135.0 0.3 3e-39 134.8 0.3 1.0 1 0 0 1 1 1 1 Cutinase Abhydrolase_8 PF06259.12 KXL48981.1 - 0.001 18.7 0.1 0.0012 18.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase Abhydrolase_2 PF02230.16 KXL48981.1 - 0.0068 16.2 0.0 0.0089 15.8 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 KXL48981.1 - 0.021 14.5 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold PE-PPE PF08237.11 KXL48981.1 - 0.024 14.2 0.1 0.033 13.7 0.1 1.2 1 0 0 1 1 1 0 PE-PPE domain Thioesterase PF00975.20 KXL48981.1 - 0.13 12.3 0.1 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 Thioesterase domain DUF2974 PF11187.8 KXL48981.1 - 0.18 11.4 0.1 0.22 11.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF3328 PF11807.8 KXL48982.1 - 4.9e-23 82.1 0.0 5.9e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Sec3_C PF09763.9 KXL48983.1 - 1.4e-187 625.3 0.7 2.4e-186 621.2 0.0 2.1 2 0 0 2 2 2 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 KXL48983.1 - 2.4e-29 101.3 0.0 4.9e-29 100.3 0.0 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH SBP56 PF05694.11 KXL48984.1 - 9.4e-179 595.0 0.1 1.1e-178 594.8 0.1 1.0 1 0 0 1 1 1 1 56kDa selenium binding protein (SBP56) MJ1316 PF04457.12 KXL48985.1 - 5.2e-17 62.4 0.4 1.3e-16 61.1 0.4 1.7 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain Aldose_epim PF01263.20 KXL48986.1 - 8.4e-42 143.5 0.0 1.1e-41 143.2 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase MBOAT_2 PF13813.6 KXL48987.1 - 1.4e-07 31.6 9.1 3.8e-07 30.3 9.1 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Sugar_tr PF00083.24 KXL48988.1 - 5.5e-81 272.7 16.3 6.3e-81 272.5 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL48988.1 - 7.5e-22 77.7 34.7 2.4e-19 69.5 20.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXL48988.1 - 0.0023 16.9 1.3 0.0023 16.9 1.3 1.8 2 0 0 2 2 2 1 MFS_1 like family Sulfotransfer_4 PF17784.1 KXL48990.1 - 9.1e-16 58.3 0.0 9.6e-16 58.3 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Glyco_hydro_125 PF06824.11 KXL48991.1 - 4e-180 599.1 0.0 5.3e-180 598.7 0.0 1.1 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) FGGY_N PF00370.21 KXL48992.1 - 4.3e-61 206.6 0.0 5.1e-61 206.4 0.0 1.0 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KXL48992.1 - 1.2e-13 51.2 0.0 4.4e-13 49.4 0.1 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Mito_carr PF00153.27 KXL48995.1 - 2.4e-37 126.8 0.8 1.4e-13 50.6 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein ABC_membrane PF00664.23 KXL48996.1 - 4.5e-89 298.7 40.0 4.2e-46 157.8 16.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXL48996.1 - 2.8e-63 212.5 0.2 2.4e-32 112.3 0.1 2.9 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXL48996.1 - 1e-16 61.1 3.2 1.6e-09 37.6 0.2 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXL48996.1 - 8.5e-09 35.0 1.4 0.0036 17.0 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KXL48996.1 - 1.1e-08 35.3 2.1 0.011 15.6 0.2 4.1 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KXL48996.1 - 1.4e-08 35.1 1.0 0.0081 16.4 0.2 3.9 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KXL48996.1 - 2.1e-08 34.7 0.5 0.0011 19.4 0.1 3.1 3 0 0 3 3 2 2 AAA ATPase domain ABC_ATPase PF09818.9 KXL48996.1 - 7e-07 28.4 0.6 0.014 14.2 0.0 3.3 4 0 0 4 4 4 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 KXL48996.1 - 1.1e-06 28.6 0.0 0.052 13.5 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 KXL48996.1 - 2.2e-06 27.6 0.0 0.0065 16.2 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 KXL48996.1 - 3.5e-06 26.9 0.2 0.088 12.5 0.1 3.3 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.6 KXL48996.1 - 1.2e-05 25.9 0.2 0.013 16.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KXL48996.1 - 0.00024 20.8 1.3 1.2 8.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.14 KXL48996.1 - 0.00029 20.8 0.2 1.1 9.2 0.0 3.8 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KXL48996.1 - 0.00057 20.4 0.1 1.9 9.0 0.0 3.0 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.6 KXL48996.1 - 0.0011 19.2 1.0 0.74 10.1 0.1 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 KXL48996.1 - 0.0012 18.6 0.2 0.21 11.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KXL48996.1 - 0.0044 17.1 0.5 1.7 8.7 0.1 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain ATP_bind_1 PF03029.17 KXL48996.1 - 0.0064 16.3 0.0 3.2 7.5 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 KXL48996.1 - 0.0067 16.7 0.0 3.2 8.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXL48996.1 - 0.0075 16.4 0.2 5.4 7.2 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KXL48996.1 - 0.01 15.4 0.0 2.6 7.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KXL48996.1 - 0.016 14.5 0.5 4.8 6.4 0.0 3.3 3 0 0 3 3 3 0 Zeta toxin G-alpha PF00503.20 KXL48996.1 - 0.026 13.7 0.0 0.96 8.5 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit MMR_HSR1 PF01926.23 KXL48996.1 - 0.033 14.2 0.1 3.8 7.6 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.6 KXL48996.1 - 0.039 14.4 0.3 33 4.9 0.0 3.6 4 0 0 4 4 3 0 AAA domain NB-ARC PF00931.22 KXL48996.1 - 0.058 12.6 0.0 6.9 5.8 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Ploopntkinase3 PF18751.1 KXL48996.1 - 0.13 12.1 0.0 8.5 6.2 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 CbiA PF01656.23 KXL48996.1 - 4.9 7.2 4.6 16 5.5 0.1 3.2 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain HECT PF00632.25 KXL48997.1 - 2.8e-85 286.5 0.0 7.4e-85 285.1 0.0 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 KXL48997.1 - 0.43 10.5 9.7 0.019 14.7 2.9 2.5 2 0 0 2 2 2 0 IQ calmodulin-binding motif MFS_1 PF07690.16 KXL48998.1 - 1.1e-24 87.0 32.6 1.1e-24 87.0 32.6 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 KXL48998.1 - 3.2e-06 26.0 14.5 1.2e-05 24.1 0.9 2.6 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 KXL48998.1 - 0.0048 15.8 1.0 0.0048 15.8 1.0 3.0 1 1 2 3 3 3 2 MFS_1 like family Utp14 PF04615.13 KXL48999.1 - 1e-163 546.8 67.0 2.4e-105 353.8 50.9 3.1 1 1 2 3 3 3 2 Utp14 protein MRP-L27 PF09809.9 KXL49000.1 - 8.2e-20 70.7 0.2 8.9e-20 70.6 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 FGGY_C PF02782.16 KXL49003.1 - 1.7e-57 194.3 1.5 2.1e-57 194.1 1.5 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Glyco_hydro_1 PF00232.18 KXL49004.1 - 1e-106 357.1 1.0 1.2e-106 356.8 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 NS3_envE PF02723.14 KXL49006.1 - 4.2 7.5 8.3 2.6 8.2 1.0 2.1 2 0 0 2 2 2 0 Non-structural protein NS3/Small envelope protein E HLH PF00010.26 KXL49007.1 - 1.8e-09 37.4 0.1 3.8e-09 36.4 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain GIT1_C PF12205.8 KXL49007.1 - 0.0043 17.2 1.7 0.011 15.8 1.7 1.7 1 1 0 1 1 1 1 G protein-coupled receptor kinase-interacting protein 1 C term DUF5333 PF17267.2 KXL49007.1 - 0.01 16.0 1.0 0.031 14.5 0.3 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5333) MBF1 PF08523.10 KXL49007.1 - 0.022 15.2 1.0 0.032 14.7 0.3 1.7 1 1 1 2 2 2 0 Multiprotein bridging factor 1 DUF3886 PF13025.6 KXL49007.1 - 0.04 14.1 0.4 0.04 14.1 0.4 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3886) ERM PF00769.19 KXL49007.1 - 0.066 13.0 3.0 0.07 12.9 3.0 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family LPP PF04728.13 KXL49007.1 - 0.066 13.6 0.4 0.15 12.5 0.4 1.6 1 0 0 1 1 1 0 Lipoprotein leucine-zipper DUF2229 PF09989.9 KXL49007.1 - 0.095 12.3 0.5 0.098 12.3 0.5 1.1 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) GrpE PF01025.19 KXL49007.1 - 0.11 12.1 1.6 0.18 11.5 1.5 1.4 1 1 0 1 1 1 0 GrpE Pox_A30L_A26L PF06086.12 KXL49007.1 - 0.13 11.9 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein LamB_YcsF PF03746.16 KXL49008.1 - 2.6e-83 279.4 0.0 3e-83 279.2 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family CT_A_B PF02626.15 KXL49009.1 - 2.9e-77 259.9 0.0 4.5e-77 259.2 0.0 1.3 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 KXL49009.1 - 1.9e-59 200.7 0.0 3.3e-59 199.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KXL49009.1 - 2.3e-39 134.4 0.0 1.3e-38 131.9 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KXL49009.1 - 4.6e-32 110.3 0.0 1e-31 109.2 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CT_C_D PF02682.16 KXL49009.1 - 1.3e-31 109.9 0.0 2.4e-31 109.1 0.0 1.4 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_lipoyl PF00364.22 KXL49009.1 - 8.6e-10 38.3 2.5 1.1e-09 38.0 0.9 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KXL49009.1 - 5.5e-09 35.9 0.0 1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 KXL49009.1 - 7.7e-07 28.9 6.1 0.00016 21.4 0.4 3.4 2 1 1 3 3 3 2 Biotin-lipoyl like ATP-grasp PF02222.22 KXL49009.1 - 0.0006 19.4 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.6 KXL49009.1 - 0.035 13.5 0.0 0.09 12.2 0.0 1.6 2 0 0 2 2 2 0 ATP-grasp domain HlyD_3 PF13437.6 KXL49009.1 - 0.084 13.6 1.3 0.53 11.0 0.5 2.4 1 1 1 2 2 2 0 HlyD family secretion protein Arb2 PF09757.9 KXL49010.1 - 2.4e-92 308.7 2.2 3.2e-92 308.3 2.2 1.2 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 KXL49010.1 - 3.8e-84 282.8 0.1 6.4e-84 282.0 0.1 1.4 1 0 0 1 1 1 1 Histone deacetylase domain DUF3431 PF11913.8 KXL49010.1 - 0.035 13.9 0.1 0.079 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3431) VSP PF03302.13 KXL49011.1 - 0.0047 15.8 3.1 0.0075 15.2 3.1 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein MGC-24 PF05283.11 KXL49011.1 - 0.0048 17.3 5.4 0.0077 16.7 0.7 2.3 2 0 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin CYYR1 PF10873.8 KXL49011.1 - 0.023 15.2 0.0 0.06 13.8 0.0 1.8 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Aldo_ket_red PF00248.21 KXL49013.1 - 1.5e-44 152.4 0.1 2.4e-43 148.4 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family ColG_sub PF18496.1 KXL49013.1 - 0.075 13.2 0.1 0.2 11.8 0.0 1.7 2 0 0 2 2 2 0 Collagenase G catalytic helper subdomain CTD_bind PF04818.13 KXL49014.1 - 5.8e-08 33.4 0.0 1.3e-07 32.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 KXL49014.1 - 1e-05 25.3 0.0 1.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Citrate_synt PF00285.21 KXL49015.1 - 5.1e-104 348.2 0.0 6.7e-104 347.8 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 KXL49015.1 - 0.11 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Eclosion hormone Ribosomal_L11 PF00298.19 KXL49015.1 - 0.13 12.8 0.1 0.47 11.0 0.1 2.0 2 0 0 2 2 2 0 Ribosomal protein L11, RNA binding domain Mito_carr PF00153.27 KXL49016.1 - 2.2e-29 101.2 6.1 2.1e-13 50.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein RabGAP-TBC PF00566.18 KXL49017.1 - 7.1e-38 130.4 4.3 1.5e-37 129.4 4.3 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 KXL49017.1 - 1.1e-07 31.5 0.0 1.4e-05 24.6 0.0 3.0 1 1 1 2 2 2 1 Rab-binding domain (RBD) Pga1 PF10333.9 KXL49018.1 - 0.00039 20.3 0.3 0.0029 17.5 0.3 2.1 1 1 0 1 1 1 1 GPI-Mannosyltransferase II co-activator Tubulin PF00091.25 KXL49019.1 - 6.2e-67 225.6 0.0 8.7e-67 225.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KXL49019.1 - 8.2e-49 165.0 0.1 1.4e-48 164.2 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KXL49019.1 - 0.0018 18.0 0.0 0.0042 16.8 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain WW PF00397.26 KXL49020.1 - 1.8e-11 43.9 0.5 6.4e-11 42.2 0.5 2.0 1 0 0 1 1 1 1 WW domain Ras PF00071.22 KXL49021.1 - 2.5e-65 219.0 0.6 2.9e-65 218.8 0.6 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXL49021.1 - 8e-36 122.9 0.1 1.5e-35 122.0 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXL49021.1 - 2.2e-16 59.8 0.1 2.5e-16 59.6 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KXL49021.1 - 1.2e-05 25.3 0.4 0.14 12.0 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KXL49021.1 - 2e-05 24.7 0.0 0.00012 22.1 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXL49021.1 - 4.7e-05 23.0 0.4 0.00013 21.6 0.2 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KXL49021.1 - 0.00027 20.4 0.1 0.00035 20.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KXL49021.1 - 0.0006 19.3 0.0 0.00087 18.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.29 KXL49021.1 - 0.00094 19.6 0.1 0.16 12.4 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 KXL49021.1 - 0.0036 16.8 0.0 0.022 14.3 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B TniB PF05621.11 KXL49021.1 - 0.0053 16.2 0.0 0.016 14.6 0.0 1.7 2 0 0 2 2 2 1 Bacterial TniB protein AAA_16 PF13191.6 KXL49021.1 - 0.007 16.8 0.0 0.0091 16.4 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXL49021.1 - 0.043 14.1 0.0 0.077 13.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXL49021.1 - 0.057 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 KXL49021.1 - 0.06 13.3 0.1 0.15 12.1 0.0 1.9 1 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Septin PF00735.18 KXL49021.1 - 0.066 12.5 0.1 0.2 10.9 0.0 1.7 2 0 0 2 2 2 0 Septin AAA_7 PF12775.7 KXL49021.1 - 0.08 12.5 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 KXL49021.1 - 0.099 13.2 0.1 0.19 12.3 0.1 1.7 1 1 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 KXL49021.1 - 0.17 11.5 0.1 1.6 8.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain PHD PF00628.29 KXL49022.1 - 0.018 14.9 7.5 0.064 13.2 7.5 2.1 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.6 KXL49022.1 - 0.11 12.7 4.5 0.39 11.0 4.5 1.9 1 0 0 1 1 1 0 PHD-like zinc-binding domain DAO PF01266.24 KXL49023.1 - 7.1e-31 108.1 0.0 8.4e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXL49023.1 - 1.3e-06 28.5 0.0 0.0026 17.8 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KXL49023.1 - 3.1e-05 23.0 0.2 0.05 12.5 0.0 3.0 3 0 0 3 3 3 2 Tryptophan halogenase Pyr_redox_2 PF07992.14 KXL49023.1 - 0.00011 21.5 0.0 0.0029 16.9 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXL49023.1 - 0.00014 21.1 0.1 0.00089 18.4 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A GMC_oxred_N PF00732.19 KXL49023.1 - 0.00036 20.0 0.1 0.019 14.4 0.1 2.1 2 0 0 2 2 2 1 GMC oxidoreductase Shikimate_DH PF01488.20 KXL49023.1 - 0.015 15.4 0.0 0.047 13.7 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KXL49023.1 - 0.018 15.3 0.0 0.046 14.0 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 KXL49023.1 - 0.023 14.3 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 KXL49023.1 - 0.055 13.7 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_Gly3P_dh_N PF01210.23 KXL49023.1 - 0.063 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.18 KXL49023.1 - 0.072 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Lycopene_cycl PF05834.12 KXL49023.1 - 0.089 11.8 0.0 8.3 5.3 0.0 2.5 2 1 1 3 3 3 0 Lycopene cyclase protein Mcl1_mid PF12341.8 KXL49024.1 - 1.3e-101 339.9 0.1 1.4e-100 336.5 0.0 2.3 2 1 1 3 3 3 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 KXL49024.1 - 3.3e-12 46.6 0.1 0.0016 18.7 0.1 6.8 2 1 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXL49024.1 - 1e-08 35.6 3.0 0.036 14.9 0.1 6.6 7 0 0 7 7 7 1 WD domain, G-beta repeat DNA_pol_alpha_N PF12254.8 KXL49024.1 - 0.033 14.3 0.4 0.087 12.9 0.4 1.7 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal CHZ PF09649.10 KXL49025.1 - 9.6e-16 57.0 1.7 9.6e-16 57.0 1.7 3.0 4 0 0 4 4 4 1 Histone chaperone domain CHZ Tub_N PF16322.5 KXL49025.1 - 6.8 7.0 15.3 7.8 6.8 15.3 1.1 1 0 0 1 1 1 0 Tubby N-terminal BUD22 PF09073.10 KXL49025.1 - 8.4 5.6 22.1 9.1 5.5 22.1 1.0 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 KXL49025.1 - 10 4.1 34.7 11 4.0 34.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi Mito_carr PF00153.27 KXL49026.1 - 8.5e-54 179.5 0.2 6.9e-18 64.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pyr_redox_2 PF07992.14 KXL49027.1 - 7e-10 38.6 0.0 4.8e-06 26.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXL49027.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lactamase_B PF00753.27 KXL49028.1 - 7.5e-21 75.0 1.2 1.3e-20 74.3 0.7 1.6 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXL49028.1 - 6.4e-08 32.4 0.1 1.3e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXL49028.1 - 0.041 13.8 0.1 0.079 12.9 0.1 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain SLATT_fungal PF18142.1 KXL49029.1 - 7.9e-28 96.9 0.1 1.2e-27 96.2 0.1 1.3 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain Vac7 PF12751.7 KXL49029.1 - 0.0061 16.0 0.5 0.0083 15.6 0.5 1.2 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 DUF3792 PF12670.7 KXL49029.1 - 0.02 15.0 4.8 0.031 14.5 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) Phage_holin_3_6 PF07332.11 KXL49029.1 - 0.083 12.9 0.8 0.15 12.1 0.8 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4231 PF14015.6 KXL49029.1 - 0.11 13.0 0.1 0.17 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Aldo_ket_red PF00248.21 KXL49030.1 - 3.5e-67 226.7 0.0 4e-67 226.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2985 PF11204.8 KXL49031.1 - 5.4e-21 74.5 2.9 8.9e-21 73.8 2.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Phage_holin_3_6 PF07332.11 KXL49031.1 - 0.0031 17.5 0.0 0.3 11.1 0.0 2.2 2 0 0 2 2 2 1 Putative Actinobacterial Holin-X, holin superfamily III Ureide_permease PF07168.11 KXL49031.1 - 0.014 14.2 0.0 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 Ureide permease Sugar_tr PF00083.24 KXL49031.1 - 0.07 12.0 0.3 0.14 11.0 0.3 1.3 1 0 0 1 1 1 0 Sugar (and other) transporter TPR_10 PF13374.6 KXL49032.1 - 1.1e-103 336.7 11.8 4.9e-13 48.5 0.3 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_12 PF13424.6 KXL49032.1 - 4.6e-73 241.5 9.1 8e-18 64.5 0.1 8.1 1 1 6 8 8 8 8 Tetratricopeptide repeat TPR_7 PF13176.6 KXL49032.1 - 3.3e-30 101.9 13.9 0.012 15.6 0.0 9.8 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_1 PF00515.28 KXL49032.1 - 9.1e-16 56.9 10.6 0.28 11.1 0.1 9.4 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_4 PF07721.14 KXL49032.1 - 6.7e-14 51.0 2.7 0.76 10.6 0.0 7.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 KXL49032.1 - 1.5e-13 50.1 11.4 0.75 10.3 0.0 9.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXL49032.1 - 5.1e-13 49.4 1.6 0.026 15.2 0.0 7.8 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXL49032.1 - 2e-12 46.2 16.4 0.17 12.0 0.0 9.0 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.6 KXL49032.1 - 8.7e-11 41.2 6.7 0.65 10.4 0.0 8.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KXL49032.1 - 1.3e-09 37.9 15.7 2e-05 24.1 4.8 2.9 1 1 1 2 2 2 2 MalT-like TPR region TPR_19 PF14559.6 KXL49032.1 - 1.5e-07 31.8 5.7 2.5 8.7 0.0 7.4 5 3 4 9 9 8 2 Tetratricopeptide repeat PPR PF01535.20 KXL49032.1 - 0.012 15.8 0.2 18 5.9 0.0 4.9 5 0 0 5 5 5 0 PPR repeat TPR_14 PF13428.6 KXL49032.1 - 0.064 14.1 12.6 47 5.2 0.0 7.2 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF1897 PF09005.10 KXL49032.1 - 0.069 12.6 7.0 9 5.9 0.0 4.8 6 0 0 6 6 6 0 Domain of unknown function (DUF1897) DUF1476 PF07345.11 KXL49032.1 - 2.8 8.4 4.8 1 9.8 0.2 2.6 3 0 0 3 3 3 0 ATPase inhibitor subunit zeta DUF3446 PF11928.8 KXL49033.1 - 6.3 7.2 7.7 1.7 9.0 2.5 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain Pkinase_Tyr PF07714.17 KXL49035.1 - 1.2e-11 44.4 0.0 9.1e-10 38.2 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KXL49035.1 - 3.1e-09 36.6 0.0 6.2e-09 35.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain RtxA PF07634.11 KXL49036.1 - 2.6e-05 24.3 1.4 1e+02 3.8 0.0 6.1 6 0 0 6 6 6 2 RtxA repeat FAD_binding_8 PF08022.12 KXL49037.1 - 6.6e-13 48.7 0.0 1.8e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KXL49037.1 - 4.4e-05 23.7 0.0 0.0025 17.9 0.0 2.6 2 1 1 3 3 3 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KXL49037.1 - 9.4e-05 22.5 6.4 9.4e-05 22.5 6.4 2.6 2 1 0 2 2 2 1 Ferric reductase like transmembrane component BIR PF00653.21 KXL49038.1 - 4.9e-05 23.9 0.0 9.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain Pkinase PF00069.25 KXL49039.1 - 1.6e-10 40.8 0.0 2.3e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL49039.1 - 1.1e-06 28.2 0.0 1.5e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3723 PF12520.8 KXL49040.1 - 1.4e-153 512.2 7.1 6.8e-121 404.4 2.8 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3723) FTCD_N PF07837.12 KXL49043.1 - 0.0068 16.2 0.5 0.021 14.6 0.3 1.8 2 0 0 2 2 2 1 Formiminotransferase domain, N-terminal subdomain CAF1-p150_C2 PF15539.6 KXL49043.1 - 0.065 12.7 0.3 0.095 12.2 0.3 1.2 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term Nucleo_P87 PF07267.11 KXL49043.1 - 0.4 9.5 1.7 0.5 9.2 1.7 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 ORC5_C PF14630.6 KXL49045.1 - 2.3e-63 214.4 0.0 3.9e-63 213.6 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 KXL49045.1 - 1.3e-11 45.1 0.0 3.6e-11 43.7 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain dCMP_cyt_deam_1 PF00383.23 KXL49046.1 - 5.1e-06 26.3 1.8 8.4e-05 22.4 1.8 2.7 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXL49046.1 - 7.7e-05 22.5 0.1 0.00069 19.4 0.0 2.2 2 1 0 2 2 2 1 MafB19-like deaminase SUIM_assoc PF16619.5 KXL49046.1 - 0.015 15.4 0.1 0.015 15.4 0.1 1.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TT_ORF2 PF02957.15 KXL49046.1 - 3.1 8.8 9.3 5.3 8.0 5.4 2.6 2 0 0 2 2 2 0 TT viral ORF2 BRF1 PF07741.13 KXL49046.1 - 3.7 8.0 7.6 7.7 6.9 1.6 2.5 2 0 0 2 2 2 0 Brf1-like TBP-binding domain PEHE PF15275.6 KXL49046.1 - 6.2 7.5 8.5 0.36 11.5 2.7 1.9 2 0 0 2 2 2 0 PEHE domain DUF2790 PF10976.8 KXL49047.1 - 0.1 12.6 0.6 0.18 11.8 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2790) Ge1_WD40 PF16529.5 KXL49048.1 - 0.23 10.4 0.0 3.8 6.4 0.0 2.4 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Formyl_trans_N PF00551.19 KXL49049.1 - 2.1e-37 128.6 0.1 2.9e-37 128.2 0.1 1.2 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 KXL49049.1 - 1.5e-12 47.0 0.0 3.3e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 KXL49049.1 - 3e-06 27.1 0.0 8.1e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 ACT domain eIF-5_eIF-2B PF01873.17 KXL49050.1 - 9.8e-40 135.1 0.0 2.1e-39 134.0 0.0 1.6 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 KXL49050.1 - 3.5e-21 75.1 0.3 3.5e-21 75.1 0.3 2.2 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Pox_vIL-18BP PF05566.12 KXL49050.1 - 0.07 13.3 0.2 0.2 11.9 0.0 1.8 2 0 0 2 2 2 0 Orthopoxvirus interleukin 18 binding protein GFRP PF06399.13 KXL49050.1 - 0.13 12.2 0.1 0.37 10.7 0.1 1.7 1 0 0 1 1 1 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) Zn-ribbon_8 PF09723.10 KXL49050.1 - 0.16 12.1 0.4 0.4 10.8 0.4 1.6 1 0 0 1 1 1 0 Zinc ribbon domain HK PF02110.15 KXL49051.1 - 2.9e-75 252.8 0.6 5.5e-75 251.9 0.6 1.5 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 KXL49051.1 - 6.1e-57 191.9 4.4 6.1e-57 191.9 4.4 1.8 2 0 0 2 2 2 1 Thiamine monophosphate synthase Phos_pyr_kin PF08543.12 KXL49051.1 - 0.0019 17.7 0.0 0.0075 15.7 0.0 1.9 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase Abhydrolase_1 PF00561.20 KXL49052.1 - 4.3e-23 82.3 0.1 1.4e-17 64.2 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXL49052.1 - 1.9e-12 48.2 0.1 2e-12 48.2 0.1 1.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXL49052.1 - 1.3e-09 37.7 0.0 8.8e-09 35.0 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Pinin_SDK_memA PF04696.13 KXL49053.1 - 7e-26 90.8 15.5 7e-26 90.8 15.5 2.2 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region RSB_motif PF16294.5 KXL49053.1 - 0.015 15.5 8.3 0.015 15.5 8.3 3.3 3 2 0 3 3 3 0 RNSP1-SAP18 binding (RSB) motif GvpL_GvpF PF06386.11 KXL49053.1 - 2.2 8.2 13.0 2.4 8.0 12.1 1.7 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF2098 PF09871.9 KXL49053.1 - 8.4 6.8 8.2 18 5.8 0.0 2.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) MFS_1 PF07690.16 KXL49054.1 - 1.2e-21 77.1 46.3 3.5e-20 72.2 46.3 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Lum_binding PF00677.17 KXL49054.1 - 0.072 13.1 2.1 1.1 9.3 0.1 2.5 2 1 0 2 2 2 0 Lumazine binding domain DNA_pol_B_thumb PF14791.6 KXL49055.1 - 2.7e-21 75.5 0.2 1.2e-20 73.5 0.2 2.1 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 KXL49055.1 - 1.4e-19 69.6 0.6 4.5e-19 68.0 0.6 2.0 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.6 KXL49055.1 - 2.5e-17 63.1 0.1 1.1e-16 61.0 0.1 2.0 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 KXL49055.1 - 2.6e-07 30.9 0.1 6.4e-07 29.6 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain Filaggrin PF03516.13 KXL49055.1 - 0.84 10.4 4.4 4 8.2 3.5 2.3 2 0 0 2 2 2 0 Filaggrin MMR_HSR1 PF01926.23 KXL49056.1 - 2.3e-14 53.4 0.0 4.4e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXL49056.1 - 1.3e-06 28.4 1.3 3.6e-06 27.0 1.3 1.6 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KXL49056.1 - 4.6e-05 23.0 0.1 7.4e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KXL49056.1 - 0.0049 17.0 0.2 0.099 12.7 0.1 2.6 1 1 1 2 2 2 1 Dynamin family AIG1 PF04548.16 KXL49056.1 - 0.0075 15.6 0.0 0.033 13.5 0.0 1.9 2 0 0 2 2 2 1 AIG1 family Septin PF00735.18 KXL49056.1 - 0.015 14.6 0.0 0.029 13.6 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 KXL49056.1 - 0.019 15.3 0.1 0.032 14.6 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KXL49056.1 - 0.031 14.8 0.2 0.07 13.7 0.2 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KXL49056.1 - 0.084 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF815 PF05673.13 KXL49056.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Roc PF08477.13 KXL49056.1 - 0.13 12.5 0.1 0.24 11.6 0.1 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 KXL49056.1 - 0.15 11.1 0.2 0.22 10.5 0.2 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) MCM PF00493.23 KXL49056.1 - 0.17 11.0 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain Arf PF00025.21 KXL49056.1 - 0.2 11.1 0.0 13 5.2 0.0 2.2 1 1 0 2 2 2 0 ADP-ribosylation factor family Ras PF00071.22 KXL49057.1 - 2.3e-53 180.1 0.0 3.1e-53 179.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXL49057.1 - 6.7e-19 68.3 0.0 1.1e-18 67.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXL49057.1 - 2.3e-06 27.2 0.0 3.3e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXL49057.1 - 0.11 12.0 0.1 0.57 9.7 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Fes1 PF08609.10 KXL49058.1 - 0.044 14.6 0.2 0.25 12.2 0.2 2.4 1 0 0 1 1 1 0 Nucleotide exchange factor Fes1 Beta_elim_lyase PF01212.21 KXL49059.1 - 1.9e-28 99.6 0.1 2.4e-28 99.3 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KXL49059.1 - 0.00026 20.4 0.0 0.00044 19.7 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Sec39 PF08314.11 KXL49061.1 - 3.8e-238 792.8 0.0 4.5e-238 792.5 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 DUF4441 PF14536.6 KXL49061.1 - 0.16 12.2 0.0 0.46 10.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) MMR_HSR1_Xtn PF16897.5 KXL49062.1 - 1.1e-39 134.7 0.8 1.1e-39 134.7 0.8 1.9 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KXL49062.1 - 5.6e-22 77.5 0.3 1.2e-21 76.5 0.3 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KXL49062.1 - 6.1e-21 74.6 0.1 2.6e-20 72.6 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXL49062.1 - 4.4e-09 36.1 0.1 2.2e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KXL49062.1 - 0.00051 20.2 0.1 0.13 12.3 0.0 2.6 2 1 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.27 KXL49062.1 - 0.00051 19.6 0.1 10 5.6 0.0 3.8 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain MeaB PF03308.16 KXL49062.1 - 0.0073 15.3 0.1 0.02 13.9 0.1 1.7 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RRG8 PF17068.5 KXL49062.1 - 0.037 13.4 0.7 0.063 12.7 0.7 1.3 1 0 0 1 1 1 0 Required for respiratory growth protein 8 mitochondrial RsgA_GTPase PF03193.16 KXL49062.1 - 0.084 12.8 0.7 5.5 6.9 0.0 3.1 2 1 1 3 3 3 0 RsgA GTPase zf-C2H2 PF00096.26 KXL49063.1 - 3.9e-06 27.0 20.4 2.1e-05 24.7 3.8 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXL49063.1 - 3.3e-05 24.1 6.9 4.6e-05 23.7 3.8 2.5 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXL49063.1 - 4.8e-05 23.9 2.3 4.8e-05 23.9 2.3 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXL49063.1 - 0.00056 20.1 1.0 0.0017 18.6 1.0 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KXL49063.1 - 0.00086 19.2 1.8 0.002 18.1 1.8 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger FOXP-CC PF16159.5 KXL49063.1 - 0.1 13.2 9.1 0.12 13.0 1.3 3.4 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-met PF12874.7 KXL49063.1 - 0.12 12.8 0.7 0.39 11.2 0.7 1.9 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-TRAF PF02176.18 KXL49063.1 - 0.17 12.6 8.7 0.54 11.0 2.9 2.4 2 0 0 2 2 2 0 TRAF-type zinc finger zf-C2H2_8 PF15909.5 KXL49063.1 - 0.48 10.7 3.5 1.2 9.5 3.5 1.6 1 0 0 1 1 1 0 C2H2-type zinc ribbon SNAP-25 PF00835.19 KXL49063.1 - 1.6 9.1 4.4 0.8 10.1 0.1 2.6 2 0 0 2 2 2 0 SNAP-25 family zf-C2HE PF16278.5 KXL49063.1 - 3.9 8.0 5.7 7.5 7.1 4.7 2.0 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger DUF4451 PF14616.6 KXL49064.1 - 2.1e-17 63.5 2.1 3.4e-17 62.8 2.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) zf-RING_7 PF02591.15 KXL49064.1 - 0.07 13.3 0.3 0.14 12.4 0.3 1.5 1 0 0 1 1 1 0 C4-type zinc ribbon domain p450 PF00067.22 KXL49066.1 - 7.5e-65 219.5 0.0 1.2e-64 218.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.24 KXL49067.1 - 4.7e-87 292.7 30.6 5.5e-87 292.5 30.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL49067.1 - 5.3e-17 61.8 35.3 7e-14 51.5 11.6 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.32 KXL49069.1 - 3.7e-25 87.7 7.5 4.7e-06 27.2 0.1 7.3 8 0 0 8 8 8 5 WD domain, G-beta repeat F-box-like PF12937.7 KXL49069.1 - 1.2e-13 50.7 0.8 2.7e-13 49.6 0.8 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXL49069.1 - 1.3e-09 37.7 0.3 1.3e-09 37.7 0.3 1.9 2 0 0 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 KXL49069.1 - 2e-05 24.8 0.0 0.44 10.9 0.0 4.3 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXL49069.1 - 0.00052 18.8 0.0 0.089 11.4 0.0 3.2 3 1 0 4 4 4 1 Nucleoporin Nup120/160 WD40_like PF17005.5 KXL49069.1 - 0.0042 16.5 0.0 40 3.4 0.0 3.8 3 1 1 4 4 4 0 WD40-like domain MraZ PF02381.18 KXL49069.1 - 0.0074 16.2 0.5 0.93 9.5 0.0 3.1 2 1 1 3 3 3 1 MraZ protein, putative antitoxin-like PQQ_2 PF13360.6 KXL49069.1 - 0.013 15.1 0.3 1 8.9 0.3 2.6 1 1 1 2 2 2 0 PQQ-like domain F-box_4 PF15966.5 KXL49069.1 - 0.047 13.6 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 F-box PQQ PF01011.21 KXL49069.1 - 0.088 12.8 0.1 10 6.3 0.1 3.3 3 0 0 3 3 3 0 PQQ enzyme repeat Efg1 PF10153.9 KXL49071.1 - 4.2e-34 117.3 10.8 2e-33 115.1 5.7 2.4 2 0 0 2 2 2 2 rRNA-processing protein Efg1 PIN_8 PF18476.1 KXL49071.1 - 0.094 12.6 3.6 0.18 11.6 1.2 2.2 2 1 0 2 2 2 0 PIN like domain DBD_Tnp_Mut PF03108.15 KXL49072.1 - 7.4e-05 22.7 1.6 9.8e-05 22.3 0.1 1.9 2 0 0 2 2 2 1 MuDR family transposase zf-CHC2 PF01807.20 KXL49072.1 - 0.067 13.0 0.0 0.81 9.5 0.0 2.3 2 0 0 2 2 2 0 CHC2 zinc finger MAGE PF01454.19 KXL49075.1 - 2.1e-54 184.5 0.0 2.7e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 MAGE family Fe_dep_repress PF01325.19 KXL49075.1 - 0.0053 16.9 0.7 0.014 15.6 0.0 1.9 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain MarR_2 PF12802.7 KXL49075.1 - 0.078 12.9 0.6 0.21 11.5 0.1 2.0 2 0 0 2 2 2 0 MarR family MRI PF15325.6 KXL49075.1 - 1.9 9.6 5.2 0.49 11.5 1.5 1.9 2 0 0 2 2 2 0 Modulator of retrovirus infection RMMBL PF07521.12 KXL49076.1 - 0.17 11.9 0.0 0.42 10.6 0.0 1.6 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain Peptidase_M28 PF04389.17 KXL49077.1 - 2.3e-34 118.8 0.0 3.6e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KXL49077.1 - 0.00026 20.8 0.0 0.00052 19.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Stb3 PF10330.9 KXL49078.1 - 1.8e-29 101.6 0.0 3.5e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 Putative Sin3 binding protein Spem1 PF15670.5 KXL49078.1 - 0.07 12.7 1.0 0.11 12.1 0.2 1.6 2 0 0 2 2 2 0 Spermatid maturation protein 1 UPF0086 PF01868.16 KXL49080.1 - 0.034 14.1 0.6 0.042 13.8 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function UPF0086 Lactamase_B_2 PF12706.7 KXL49081.1 - 7.3e-33 113.8 0.0 1.3e-32 113.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXL49081.1 - 6.1e-14 52.2 0.0 9.4e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KXL49081.1 - 0.00057 20.0 0.4 0.25 11.3 0.3 2.4 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily YHS PF04945.13 KXL49081.1 - 0.16 12.1 1.2 0.92 9.7 0.0 2.6 3 0 0 3 3 3 0 YHS domain Aminotran_1_2 PF00155.21 KXL49082.1 - 1.3e-83 281.2 0.0 1.6e-83 280.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KXL49082.1 - 1.8e-05 23.4 0.0 3.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KXL49082.1 - 7.3e-05 21.9 0.1 0.00015 20.9 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KXL49082.1 - 0.0046 16.3 0.3 0.0078 15.6 0.3 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF3405 PF11885.8 KXL49082.1 - 0.046 12.3 0.1 0.068 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) APH PF01636.23 KXL49084.1 - 0.015 15.2 0.0 0.024 14.6 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 KXL49086.1 - 9.4e-50 169.4 0.0 1.5e-49 168.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL49086.1 - 1.6e-28 99.7 0.0 2.4e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXL49086.1 - 0.00071 19.0 0.0 0.0014 18.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXL49086.1 - 0.032 14.1 0.3 2.3 8.1 0.0 3.0 3 1 1 4 4 4 0 Phosphotransferase enzyme family SSB PF00436.25 KXL49087.1 - 1.1e-16 60.8 0.0 1.3e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Thioredoxin PF00085.20 KXL49089.1 - 0.0027 17.7 0.0 0.0044 17.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin HSF_DNA-bind PF00447.17 KXL49090.1 - 1.2e-26 93.1 0.1 2.9e-26 91.9 0.1 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding Peptidase_C80 PF11713.8 KXL49090.1 - 0.11 12.7 0.2 2.7 8.2 0.0 2.6 2 0 0 2 2 2 0 Peptidase C80 family DUF4413 PF14372.6 KXL49090.1 - 0.19 12.1 0.7 0.33 11.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4413) BLOC1_2 PF10046.9 KXL49090.1 - 0.42 11.0 4.9 3.7 7.9 0.3 2.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6_N PF17675.1 KXL49090.1 - 1.1 9.8 12.0 0.11 13.0 3.0 3.1 4 0 0 4 4 4 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 KXL49090.1 - 3.3 8.0 9.8 0.11 12.7 0.4 2.5 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding EamA PF00892.20 KXL49093.1 - 2.7e-07 30.8 10.3 2.7e-07 30.8 10.3 2.2 2 0 0 2 2 2 1 EamA-like transporter family ORC6 PF05460.13 KXL49094.1 - 1e-17 64.5 0.0 2.7e-15 56.5 0.0 2.1 1 1 1 2 2 2 2 Origin recognition complex subunit 6 (ORC6) FRG2 PF15315.6 KXL49094.1 - 3 8.0 5.8 1.6 8.9 3.5 1.6 1 1 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 4HBT PF03061.22 KXL49095.1 - 1.4e-05 25.4 0.0 2.8e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily Zn_clus PF00172.18 KXL49096.1 - 4.6e-07 29.9 7.7 7.6e-07 29.2 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.13 KXL49097.1 - 5.2e-60 202.6 6.9 6.8e-60 202.2 6.9 1.1 1 0 0 1 1 1 1 RTA1 like protein WAPL PF07814.13 KXL49098.1 - 4.4e-47 160.6 0.9 7.8e-47 159.8 0.9 1.4 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin DUF383 PF04063.14 KXL49098.1 - 0.022 14.4 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF383) UPRTase PF14681.6 KXL49099.1 - 2e-77 259.3 0.0 2.7e-77 258.9 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KXL49099.1 - 0.00048 19.7 0.0 0.00071 19.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain His_biosynth PF00977.21 KXL49100.1 - 5.8e-31 107.7 0.0 7.3e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Cpn60_TCP1 PF00118.24 KXL49101.1 - 3.5e-84 283.2 10.8 9.8e-84 281.7 10.8 1.6 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF4602 PF15375.6 KXL49102.1 - 1.1e-13 51.6 2.6 1.1e-13 51.6 2.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4602) Sugar_tr PF00083.24 KXL49104.1 - 7.4e-99 331.6 24.5 8.8e-99 331.4 24.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL49104.1 - 7.3e-21 74.5 29.5 7.3e-21 74.5 29.5 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily DCP1 PF06058.13 KXL49106.1 - 2.9e-31 107.8 0.0 4.4e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family Exo_endo_phos PF03372.23 KXL49107.1 - 5.8e-06 26.0 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HEPN_LA2681 PF18733.1 KXL49107.1 - 0.14 11.4 0.2 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 LA2681-like HEPN Cyclin_C_2 PF16899.5 KXL49109.1 - 1.3e-31 109.0 0.7 5.9e-28 97.3 0.0 2.6 2 0 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 KXL49109.1 - 2.5e-12 46.7 0.4 4.7e-11 42.5 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain DUF1682 PF07946.14 KXL49109.1 - 0.0031 16.8 1.2 0.005 16.1 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) TFIIB PF00382.19 KXL49109.1 - 0.008 16.2 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 Transcription factor TFIIB repeat F-box PF00646.33 KXL49110.1 - 0.074 13.0 4.1 2.2 8.2 2.1 2.7 2 0 0 2 2 2 0 F-box domain OPT PF03169.15 KXL49111.1 - 5.9e-142 474.4 49.5 7.2e-142 474.1 49.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3453 PF11935.8 KXL49112.1 - 5.9e-66 222.4 0.1 8.9e-66 221.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) Cnd1 PF12717.7 KXL49112.1 - 0.046 13.8 0.2 1.9 8.5 0.0 3.0 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Coiled-coil_56 PF09813.9 KXL49113.1 - 0.0021 18.1 0.0 0.0025 17.8 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 AA_permease_2 PF13520.6 KXL49114.1 - 6e-49 167.0 47.8 7.7e-49 166.7 47.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXL49114.1 - 1.8e-28 99.4 37.8 2.3e-28 99.1 37.8 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3043 PF11241.8 KXL49114.1 - 1.6 8.8 9.4 6.4 6.8 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3043) Aa_trans PF01490.18 KXL49116.1 - 7.8e-30 103.9 22.4 1.4e-29 103.0 22.4 1.4 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein HAD_2 PF13419.6 KXL49118.1 - 3.7e-05 23.9 0.0 0.00013 22.1 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXL49118.1 - 0.0015 18.9 0.0 0.0027 18.0 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_33 PF13671.6 KXL49119.1 - 2.8e-08 34.0 0.0 4.4e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXL49119.1 - 4e-07 30.6 0.0 1.4e-06 28.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 KXL49119.1 - 1.6e-06 28.3 0.0 2.3e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase Cytidylate_kin PF02224.18 KXL49119.1 - 0.00061 19.6 0.0 0.0015 18.3 0.0 1.5 1 1 0 1 1 1 1 Cytidylate kinase AAA_22 PF13401.6 KXL49119.1 - 0.0013 19.0 0.0 0.003 17.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 KXL49119.1 - 0.0014 18.5 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KXL49119.1 - 0.0036 17.7 0.0 0.0068 16.8 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.6 KXL49119.1 - 0.0049 17.3 0.0 0.013 15.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 KXL49119.1 - 0.0053 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.6 KXL49119.1 - 0.0063 16.8 0.0 0.02 15.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 KXL49119.1 - 0.0066 16.6 0.0 0.017 15.2 0.0 1.7 2 0 0 2 2 1 1 Sigma-54 interaction domain AAA PF00004.29 KXL49119.1 - 0.011 16.2 0.0 0.019 15.4 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) dNK PF01712.19 KXL49119.1 - 0.019 14.8 0.0 0.34 10.7 0.0 2.1 1 1 0 2 2 2 0 Deoxynucleoside kinase AAA_5 PF07728.14 KXL49119.1 - 0.019 14.9 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 KXL49119.1 - 0.023 14.6 0.0 0.076 12.9 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 KXL49119.1 - 0.024 14.0 0.0 0.048 13.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KXL49119.1 - 0.028 14.1 0.0 0.061 13.0 0.0 1.5 2 0 0 2 2 1 0 Sigma-54 interaction domain NACHT PF05729.12 KXL49119.1 - 0.033 14.1 0.0 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 KXL49119.1 - 0.047 14.1 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase tRNA_lig_kinase PF08303.11 KXL49119.1 - 0.061 13.4 0.0 0.12 12.5 0.0 1.6 1 1 0 1 1 1 0 tRNA ligase kinase domain CPT PF07931.12 KXL49119.1 - 0.07 13.0 0.0 0.14 11.9 0.0 1.6 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_30 PF13604.6 KXL49119.1 - 0.097 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KXL49119.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain PhoH PF02562.16 KXL49119.1 - 0.12 11.8 0.0 0.28 10.6 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein AAA_23 PF13476.6 KXL49119.1 - 0.13 12.8 0.0 0.21 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KXL49119.1 - 0.13 12.0 0.0 0.19 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KXL49119.1 - 0.15 12.4 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KXL49119.1 - 0.19 12.3 0.0 0.32 11.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Bac_rhodopsin PF01036.18 KXL49120.1 - 8.5e-48 162.9 4.8 1.8e-47 161.8 4.8 1.5 1 1 0 1 1 1 1 Bacteriorhodopsin-like protein Retrotran_gag_2 PF14223.6 KXL49121.1 - 0.0015 18.2 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type HTH_psq PF05225.16 KXL49122.1 - 3.2e-05 23.6 0.0 4.5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain Amidase PF01425.21 KXL49123.1 - 7.1e-98 328.5 0.0 3.6e-97 326.2 0.0 1.8 1 1 0 1 1 1 1 Amidase GTP_EFTU PF00009.27 KXL49125.1 - 5.4e-58 195.7 0.0 9.5e-58 194.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KXL49125.1 - 1.2e-14 54.0 0.0 3.4e-14 52.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KXL49125.1 - 2.4e-10 40.6 0.0 7.8e-10 39.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KXL49125.1 - 1.5e-07 31.4 0.1 4.8e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_IV PF03764.18 KXL49125.1 - 0.0018 18.1 0.0 0.0046 16.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 KXL49125.1 - 0.031 14.4 0.0 0.089 12.9 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase TBCA PF02970.16 KXL49125.1 - 0.072 13.4 3.2 0.24 11.8 3.2 1.9 1 0 0 1 1 1 0 Tubulin binding cofactor A SesA PF17107.5 KXL49126.1 - 8.1e-05 22.8 0.2 0.00015 21.9 0.2 1.4 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Helo_like_N PF17111.5 KXL49126.1 - 0.00021 20.7 0.0 0.00039 19.9 0.0 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins NPP PF08384.10 KXL49126.1 - 0.064 13.3 0.3 0.16 12.0 0.3 1.6 1 0 0 1 1 1 0 Pro-opiomelanocortin, N-terminal region FHA PF00498.26 KXL49127.1 - 2.2e-15 56.7 0.0 3.9e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 KXL49127.1 - 1.1e-13 50.7 4.6 2e-13 49.8 4.6 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KXL49127.1 - 1.3e-07 31.8 8.5 2.5e-07 30.9 8.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KXL49127.1 - 0.00015 21.6 6.8 0.00026 20.9 6.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Yop-YscD_cpl PF16697.5 KXL49127.1 - 0.00051 20.3 0.0 0.0011 19.3 0.0 1.6 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4 PF00097.25 KXL49127.1 - 0.0033 17.3 8.2 0.0058 16.5 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KXL49127.1 - 0.0044 17.0 2.5 0.0077 16.3 2.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KXL49127.1 - 0.017 15.4 6.5 0.041 14.2 6.5 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain PHD PF00628.29 KXL49127.1 - 0.025 14.5 4.9 0.054 13.4 4.9 1.6 1 0 0 1 1 1 0 PHD-finger Vps39_2 PF10367.9 KXL49127.1 - 0.064 13.7 1.3 0.11 13.0 1.3 1.4 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.6 KXL49127.1 - 0.083 12.8 8.9 0.16 11.8 8.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) OrfB_Zn_ribbon PF07282.11 KXL49127.1 - 0.14 12.1 2.6 5.2 7.1 0.8 2.5 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-RING_UBOX PF13445.6 KXL49127.1 - 0.14 12.2 8.6 0.28 11.2 8.6 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING-like PF08746.11 KXL49127.1 - 1.4 9.3 5.1 2.8 8.3 5.1 1.5 1 0 0 1 1 1 0 RING-like domain Zn_ribbon_17 PF17120.5 KXL49127.1 - 6.1 6.5 8.5 8.1 6.1 6.7 2.0 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type Peptidase_M16_C PF05193.21 KXL49128.1 - 2.4e-48 164.6 0.0 2.8e-47 161.1 0.0 2.5 2 1 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KXL49128.1 - 1.5e-42 145.1 0.0 2.8e-42 144.2 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Aminotran_1_2 PF00155.21 KXL49129.1 - 1.1e-57 195.9 0.0 1.4e-57 195.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Heme_oxygenase PF01126.20 KXL49130.1 - 1.7e-10 41.1 0.0 2.2e-09 37.4 0.0 2.1 1 1 0 1 1 1 1 Heme oxygenase MAP65_ASE1 PF03999.12 KXL49131.1 - 3.5e-75 253.9 14.4 3.5e-75 253.9 14.4 2.4 1 1 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) Prominin PF05478.11 KXL49131.1 - 0.045 11.7 4.2 0.24 9.3 0.1 2.3 2 1 0 2 2 2 0 Prominin DUF4709 PF15821.5 KXL49131.1 - 0.21 11.9 5.0 0.61 10.4 0.8 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4709) Spectrin PF00435.21 KXL49131.1 - 1.3 9.5 15.4 0.52 10.8 1.7 4.1 3 1 1 4 4 4 0 Spectrin repeat ING PF12998.7 KXL49131.1 - 1.4 9.5 8.2 0.41 11.3 1.3 3.2 2 2 2 4 4 4 0 Inhibitor of growth proteins N-terminal histone-binding TIP120 PF08623.10 KXL49132.1 - 2.1e-60 203.3 1.1 2e-59 200.1 0.2 3.1 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 KXL49132.1 - 2.9e-14 53.2 2.5 0.083 13.3 0.0 8.2 7 1 1 8 8 8 3 HEAT repeats HEAT PF02985.22 KXL49132.1 - 7.9e-11 41.2 11.5 2.1 8.9 0.0 11.1 12 0 0 12 12 12 2 HEAT repeat HEAT_EZ PF13513.6 KXL49132.1 - 1.9e-06 28.3 19.4 4.2 8.0 0.2 11.6 12 2 2 14 14 14 1 HEAT-like repeat Cnd1 PF12717.7 KXL49132.1 - 2e-06 27.9 1.7 0.11 12.6 0.0 5.6 5 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KXL49132.1 - 5.3e-06 26.2 0.2 0.028 14.0 0.0 4.0 3 0 0 3 3 3 1 CLASP N terminal RTP1_C1 PF10363.9 KXL49132.1 - 0.00027 21.1 9.8 0.62 10.3 0.0 6.7 7 1 0 7 7 7 1 Required for nuclear transport of RNA pol II C-terminus 1 MMS19_C PF12460.8 KXL49132.1 - 0.0037 16.4 10.2 1 8.4 0.3 4.9 5 1 0 5 5 5 2 RNAPII transcription regulator C-terminal FadA PF09403.10 KXL49132.1 - 0.0042 17.5 2.7 0.015 15.8 2.7 1.9 1 0 0 1 1 1 1 Adhesion protein FadA IFRD PF05004.13 KXL49132.1 - 0.013 14.7 2.2 1.3 8.0 0.0 3.8 5 1 0 5 5 5 0 Interferon-related developmental regulator (IFRD) DUF3385 PF11865.8 KXL49132.1 - 0.021 14.8 4.3 23 4.9 0.6 5.2 3 2 1 4 4 4 0 Domain of unknown function (DUF3385) Glyco_hydro_43 PF04616.14 KXL49133.1 - 1e-11 44.7 6.9 4.6e-11 42.6 6.7 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 SBF_like PF13593.6 KXL49134.1 - 2.3e-59 201.3 13.7 1e-44 153.1 7.0 2.1 1 1 1 2 2 2 2 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 KXL49134.1 - 4.4e-07 29.8 11.8 8.1e-07 28.9 11.8 1.5 1 0 0 1 1 1 1 Sodium Bile acid symporter family ADH_zinc_N PF00107.26 KXL49135.1 - 4.2e-20 72.0 0.0 1e-19 70.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXL49135.1 - 1.6e-17 63.4 0.0 3.9e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXL49135.1 - 0.0063 17.6 0.0 0.0099 16.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Transport_MerF PF11431.8 KXL49135.1 - 0.15 11.9 0.8 0.26 11.2 0.8 1.4 1 0 0 1 1 1 0 Membrane transport protein MerF zf_PR_Knuckle PF18445.1 KXL49135.1 - 0.17 11.7 0.6 0.43 10.4 0.6 1.6 1 0 0 1 1 1 0 PR zinc knuckle motif Kinetochor_Ybp2 PF08568.10 KXL49136.1 - 9e-117 391.2 0.0 1.1e-116 390.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin RD3 PF14473.6 KXL49137.1 - 0.43 10.4 5.5 0.082 12.7 0.9 2.2 3 0 0 3 3 3 0 RD3 protein IGF2_C PF08365.11 KXL49137.1 - 0.63 10.1 6.7 8.7 6.4 0.0 3.4 3 0 0 3 3 3 0 Insulin-like growth factor II E-peptide GDA1_CD39 PF01150.17 KXL49138.1 - 3.2e-103 345.6 0.0 5e-103 345.0 0.0 1.2 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family MKT1_C PF12246.8 KXL49139.1 - 4.9e-61 206.0 0.0 7e-61 205.5 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 KXL49139.1 - 2e-29 101.8 0.0 4.6e-29 100.6 0.0 1.7 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.18 KXL49139.1 - 7.4e-07 29.4 0.0 1.7e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KXL49139.1 - 4.9e-06 27.0 0.0 1.4e-05 25.5 0.0 1.8 2 0 0 2 2 2 1 XPG N-terminal domain Sugar_tr PF00083.24 KXL49140.1 - 1.5e-119 399.8 23.6 1.8e-119 399.6 23.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL49140.1 - 5.8e-21 74.8 31.7 3.8e-19 68.8 18.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 KXL49142.1 - 6.1e-30 104.4 0.0 9.3e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Mito_carr PF00153.27 KXL49143.1 - 2.2e-64 213.4 4.9 1e-23 83.1 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4748 PF15932.5 KXL49143.1 - 0.22 11.3 1.7 0.57 10.0 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4748) SOG2 PF10428.9 KXL49144.1 - 2.5 7.2 10.5 3.4 6.7 10.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Acetyltransf_10 PF13673.7 KXL49145.1 - 2e-07 31.0 0.0 4.8e-07 29.8 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXL49145.1 - 3.4e-07 30.6 0.0 7.3e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXL49145.1 - 1.8e-06 28.2 0.0 3.8e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 KXL49145.1 - 0.048 13.8 0.0 0.14 12.4 0.0 1.7 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase Cellulase PF00150.18 KXL49147.1 - 4.7e-34 118.1 2.0 1.9e-33 116.1 1.6 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF295 PF03478.18 KXL49147.1 - 0.011 15.4 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF295) GOLGA2L5 PF15070.6 KXL49147.1 - 0.1 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 FMO-like PF00743.19 KXL49148.1 - 3e-13 49.1 0.2 1.5e-12 46.8 0.0 2.0 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXL49148.1 - 2.4e-08 33.5 0.0 6.2e-08 32.2 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXL49148.1 - 9.4e-07 28.4 0.0 1.6e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXL49148.1 - 2.7e-06 26.9 0.0 0.00033 20.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXL49148.1 - 0.1 12.9 0.0 14 6.0 0.0 3.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Beta-lactamase PF00144.24 KXL49149.1 - 1.5e-42 146.0 0.0 3e-42 145.1 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase Fungal_trans PF04082.18 KXL49150.1 - 0.00067 18.8 0.3 0.0014 17.7 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain TRAPP PF04051.16 KXL49151.1 - 5e-35 120.4 0.0 5.8e-35 120.1 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Las1 PF04031.13 KXL49152.1 - 8.2e-45 152.7 0.4 1.9e-44 151.5 0.0 1.8 2 0 0 2 2 2 1 Las1-like NAD_kinase PF01513.21 KXL49153.1 - 1.9e-72 244.0 0.0 2.7e-72 243.4 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Kinesin PF00225.23 KXL49154.1 - 4.7e-111 370.9 0.1 6.4e-111 370.5 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXL49154.1 - 2.4e-26 92.4 0.0 5.5e-26 91.3 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding ZapB PF06005.12 KXL49154.1 - 0.0027 18.1 3.2 0.13 12.8 0.0 3.0 1 1 1 2 2 2 1 Cell division protein ZapB Vps53_N PF04100.12 KXL49154.1 - 0.041 12.8 3.3 0.074 12.0 3.3 1.3 1 0 0 1 1 1 0 Vps53-like, N-terminal YabA PF06156.13 KXL49154.1 - 0.096 13.3 8.6 0.84 10.3 0.6 3.5 2 1 1 3 3 3 0 Initiation control protein YabA Cep57_MT_bd PF06657.13 KXL49154.1 - 0.12 12.8 7.1 0.12 12.9 3.0 2.9 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DivIC PF04977.15 KXL49154.1 - 0.13 12.0 0.1 0.13 12.0 0.1 3.4 2 1 0 3 3 3 0 Septum formation initiator SKA2 PF16740.5 KXL49154.1 - 0.17 11.7 5.9 0.46 10.3 5.4 2.0 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Cytochrom_B562 PF07361.11 KXL49154.1 - 0.2 12.4 7.3 1.2 9.8 7.6 2.3 2 0 0 2 2 2 0 Cytochrome b562 DUF87 PF01935.17 KXL49154.1 - 0.24 11.5 6.9 0.7 9.9 0.1 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain PAPS_reduct PF01507.19 KXL49154.1 - 0.33 11.0 2.8 2.5 8.1 1.8 2.2 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family TPR_MLP1_2 PF07926.12 KXL49154.1 - 0.34 11.0 19.8 0.061 13.4 15.5 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KXL49154.1 - 0.39 9.5 10.2 0.81 8.5 10.2 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein CtIP_N PF10482.9 KXL49154.1 - 0.44 10.6 5.2 1.1 9.3 5.2 1.7 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain Filament PF00038.21 KXL49154.1 - 0.45 10.0 13.5 10 5.6 13.7 2.2 1 1 1 2 2 2 0 Intermediate filament protein Phage_Mu_Gam PF07352.12 KXL49154.1 - 0.81 9.6 7.6 8.8 6.2 3.1 2.7 1 1 0 2 2 2 0 Bacteriophage Mu Gam like protein TMF_DNA_bd PF12329.8 KXL49154.1 - 0.96 9.5 9.0 0.68 10.0 0.7 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.6 KXL49154.1 - 1.4 7.4 7.6 2.8 6.4 7.6 1.4 1 0 0 1 1 1 0 AAA domain HIP1_clath_bdg PF16515.5 KXL49154.1 - 3.8 8.2 12.4 15 6.3 12.0 2.3 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 MFS_1 PF07690.16 KXL49155.1 - 1.6e-46 158.9 26.9 1.6e-46 158.9 26.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL49155.1 - 6.6e-10 38.4 5.8 6.6e-10 38.4 5.8 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter SpoU_methylase PF00588.19 KXL49156.1 - 2.3e-27 95.9 0.0 4.1e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family PH PF00169.29 KXL49157.1 - 1.1e-26 93.4 2.4 4.2e-14 52.9 0.3 2.2 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 KXL49157.1 - 6.2e-12 45.9 2.8 1.7e-06 28.4 0.3 3.9 2 2 1 3 3 3 2 Pleckstrin homology domain PH_11 PF15413.6 KXL49157.1 - 2.2e-08 34.4 5.0 0.0041 17.5 0.3 3.7 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 KXL49157.1 - 7.1e-07 29.4 0.6 4.6e-06 26.8 0.2 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 KXL49157.1 - 9.5e-07 28.9 0.5 2.5e-05 24.3 0.2 2.4 2 1 0 2 2 2 1 PH domain PH_13 PF16652.5 KXL49157.1 - 0.011 15.6 0.6 0.023 14.5 0.1 1.7 2 0 0 2 2 2 0 Pleckstrin homology domain PH_2 PF08458.10 KXL49157.1 - 0.055 13.8 0.0 0.96 9.8 0.0 2.3 2 0 0 2 2 2 0 Plant pleckstrin homology-like region Myosin_TH1 PF06017.13 KXL49157.1 - 0.065 12.9 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Unconventional myosin tail, actin- and lipid-binding Mcp5_PH PF12814.7 KXL49157.1 - 0.14 12.3 0.4 0.61 10.2 0.1 2.0 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology Beta-lactamase PF00144.24 KXL49158.1 - 3.9e-22 78.9 0.2 8.1e-22 77.9 0.2 1.6 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KXL49158.1 - 0.00062 20.2 0.0 0.019 15.4 0.0 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3471) FAD_binding_1 PF00667.20 KXL49159.1 - 5.3e-60 202.7 0.0 6.7e-60 202.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KXL49159.1 - 2.7e-10 40.9 0.0 6.4e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KXL49159.1 - 0.029 14.7 0.0 0.35 11.2 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain DUF1653 PF07866.11 KXL49159.1 - 0.11 12.8 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1653) adh_short PF00106.25 KXL49160.1 - 1.6e-34 119.1 0.0 2.1e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL49160.1 - 1.3e-25 90.3 0.0 1.8e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KXL49160.1 - 0.018 14.5 0.1 0.099 12.1 0.0 2.0 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family KR PF08659.10 KXL49160.1 - 0.11 12.4 1.4 2.8 7.8 0.3 2.7 2 1 0 2 2 2 0 KR domain PLA2_B PF01735.18 KXL49161.1 - 6.5e-188 625.1 7.7 7.7e-188 624.9 7.7 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain POR PF01558.18 KXL49162.1 - 3.1e-09 37.2 0.0 4.7e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 KXL49162.1 - 0.00099 19.4 0.0 0.003 17.8 0.0 1.9 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 KXL49162.1 - 0.0062 16.4 0.1 0.014 15.2 0.1 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Aa_trans PF01490.18 KXL49164.1 - 8.8e-67 225.6 15.6 1e-66 225.4 15.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MerC PF03203.14 KXL49164.1 - 0.026 15.0 1.4 0.026 15.0 1.4 3.5 3 2 0 3 3 3 0 MerC mercury resistance protein Peptidase_U4 PF03419.13 KXL49164.1 - 6.7 5.9 11.7 0.55 9.5 2.2 2.3 2 0 0 2 2 2 0 Sporulation factor SpoIIGA Cu-oxidase_3 PF07732.15 KXL49168.1 - 7.7e-43 145.3 1.1 7.7e-43 145.3 1.1 2.9 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 KXL49168.1 - 2.2e-35 122.1 0.0 1.5e-30 106.4 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXL49168.1 - 5.1e-34 117.0 4.9 2.6e-28 98.5 0.6 4.1 3 1 0 3 3 3 2 Multicopper oxidase PIGA PF08288.12 KXL49169.1 - 5.6e-46 155.1 4.0 6.4e-46 154.9 1.4 2.2 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 KXL49169.1 - 2.4e-28 99.3 0.1 4.9e-28 98.2 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KXL49169.1 - 1.6e-27 96.1 0.0 2.5e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXL49169.1 - 7e-24 84.8 0.1 1.4e-23 83.8 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KXL49169.1 - 3e-12 47.3 0.0 6.5e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 KXL49169.1 - 0.00028 20.9 0.1 0.00062 19.8 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 KXL49169.1 - 0.00086 19.7 0.0 0.022 15.2 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 SRF-TF PF00319.18 KXL49170.1 - 1.2e-07 31.1 0.5 1.6e-07 30.7 0.5 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3723 PF12520.8 KXL49173.1 - 6.5e-22 77.9 0.0 8.5e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) UBA_6 PF18039.1 KXL49173.1 - 0.018 14.9 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain Death PF00531.22 KXL49173.1 - 0.05 13.8 0.0 0.094 12.9 0.0 1.5 1 0 0 1 1 1 0 Death domain RVT_1 PF00078.27 KXL49174.1 - 1.1e-28 100.3 0.0 1.8e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 KXL49174.1 - 6e-24 84.2 0.1 1.8e-23 82.6 0.1 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.24 KXL49174.1 - 1e-10 42.0 0.0 2.6e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 RNase H Exo_endo_phos PF03372.23 KXL49174.1 - 4.9e-06 26.2 0.0 1.4e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC_6 PF15288.6 KXL49174.1 - 0.58 10.0 11.5 0.014 15.3 3.3 2.6 1 1 1 2 2 2 0 Zinc knuckle HXXEE PF13787.6 KXL49177.1 - 2.6 8.9 6.8 0.32 11.8 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif DDE_1 PF03184.19 KXL49179.1 - 1.5e-28 99.6 0.0 2.3e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KXL49179.1 - 2.6e-07 30.6 0.0 6.3e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 KXL49179.1 - 3.9e-06 26.5 0.0 8.6e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain Zn_Tnp_IS1595 PF12760.7 KXL49181.1 - 0.02 14.8 0.4 0.032 14.2 0.4 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain HypA PF01155.19 KXL49181.1 - 0.035 14.1 0.1 0.06 13.4 0.1 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_10 PF10058.9 KXL49181.1 - 0.056 13.2 1.7 0.14 11.9 1.7 1.7 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Kdo PF06293.14 KXL49182.1 - 0.00079 18.8 0.0 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KXL49182.1 - 0.0087 15.4 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KXL49182.1 - 0.009 16.0 9.0 0.015 15.2 0.1 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family CDC45 PF02724.14 KXL49182.1 - 0.073 11.4 6.6 0.11 10.8 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein ARGLU PF15346.6 KXL49182.1 - 1.1 9.1 29.2 2.5 8.0 29.2 1.5 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 U79_P34 PF03064.16 KXL49182.1 - 2.1 7.6 15.9 4.1 6.7 15.9 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Afi1 PF07792.12 KXL49182.1 - 7.5 7.0 7.2 16 6.0 7.2 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking BCS1_N PF08740.11 KXL49183.1 - 8.8e-26 91.0 4.6 4.6e-13 49.6 0.2 2.3 1 1 1 2 2 2 2 BCS1 N terminal AAA PF00004.29 KXL49183.1 - 2e-17 63.9 0.0 5.3e-17 62.5 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KXL49183.1 - 0.0066 16.5 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PPV_E1_C PF00519.17 KXL49183.1 - 0.007 15.2 0.0 0.036 12.9 0.0 2.0 2 0 0 2 2 2 1 Papillomavirus helicase AAA_25 PF13481.6 KXL49183.1 - 0.0084 15.7 0.1 0.12 12.0 0.0 2.3 1 1 0 2 2 2 1 AAA domain ATPase PF06745.13 KXL49183.1 - 0.0096 15.3 0.0 0.038 13.3 0.0 1.8 2 0 0 2 2 2 1 KaiC AAA_18 PF13238.6 KXL49183.1 - 0.023 15.2 0.4 0.22 12.1 0.0 2.7 2 2 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KXL49183.1 - 0.069 13.2 0.1 0.21 11.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KXL49183.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXL49183.1 - 0.11 12.2 0.5 0.51 10.0 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KXL49183.1 - 0.11 12.8 0.3 1.1 9.7 0.1 2.5 1 1 1 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KXL49183.1 - 0.14 12.4 0.0 1.3 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KXL49183.1 - 0.14 11.6 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 KXL49183.1 - 0.15 11.2 0.3 0.3 10.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) IPT PF01745.16 KXL49183.1 - 0.17 11.2 0.0 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 Isopentenyl transferase APH PF01636.23 KXL49186.1 - 2.7e-23 83.2 0.0 3.4e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXL49186.1 - 5.7e-06 26.1 0.0 9.1e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KXL49186.1 - 0.026 14.1 0.0 0.095 12.3 0.0 1.8 2 0 0 2 2 2 0 RIO1 family SNCAIP_SNCA_bd PF16700.5 KXL49186.1 - 0.035 13.8 0.3 0.07 12.9 0.3 1.4 1 0 0 1 1 1 0 Synphilin-1 alpha-Synuclein-binding domain Myb_DNA-bind_6 PF13921.6 KXL49188.1 - 0.0076 16.5 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KXL49188.1 - 0.022 15.0 0.0 0.051 13.8 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Sigma70_r4_2 PF08281.12 KXL49188.1 - 0.067 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 MFS_1 PF07690.16 KXL49189.1 - 2.7e-34 118.7 4.6 2.7e-34 118.7 4.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL49189.1 - 3e-11 42.8 2.0 3e-11 42.8 2.0 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 KXL49189.1 - 5e-06 25.6 7.2 9.1e-06 24.8 1.5 2.8 2 0 0 2 2 2 1 MFS_1 like family MFS_4 PF06779.14 KXL49189.1 - 1.5e-05 24.5 1.3 1.5e-05 24.5 1.3 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 KXL49189.1 - 0.0044 15.6 12.2 0.12 10.9 2.6 3.0 2 2 2 4 4 3 2 MFS/sugar transport protein TRI12 PF06609.13 KXL49189.1 - 0.0056 15.2 0.6 0.01 14.3 0.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Methyltransf_23 PF13489.6 KXL49190.1 - 2.8e-22 79.3 0.0 3.7e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL49190.1 - 3e-17 63.1 0.0 6.1e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL49190.1 - 7.2e-17 62.0 0.0 1.1e-16 61.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL49190.1 - 1.2e-16 61.1 0.0 2.1e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL49190.1 - 9.7e-15 54.7 0.0 2.2e-14 53.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXL49190.1 - 2.7e-08 33.4 0.0 2e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.20 KXL49190.1 - 2.2e-06 27.0 0.0 2.8e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.14 KXL49190.1 - 4.2e-05 23.2 0.0 7.5e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 KXL49190.1 - 4.2e-05 23.4 0.0 6.5e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KXL49190.1 - 0.00011 21.7 0.0 0.0003 20.3 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 KXL49190.1 - 0.00071 19.2 0.0 0.0086 15.7 0.0 2.0 1 1 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 KXL49190.1 - 0.00075 19.5 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 KXL49190.1 - 0.002 18.0 0.0 0.003 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Pox_MCEL PF03291.16 KXL49190.1 - 0.002 17.3 0.0 0.003 16.7 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme PCMT PF01135.19 KXL49190.1 - 0.0035 17.1 0.0 0.0073 16.1 0.0 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DREV PF05219.12 KXL49190.1 - 0.0049 16.0 0.0 0.03 13.4 0.0 1.9 2 0 0 2 2 2 1 DREV methyltransferase CheR PF01739.18 KXL49190.1 - 0.0066 16.0 0.0 0.69 9.4 0.0 2.2 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_9 PF08003.11 KXL49190.1 - 0.0069 15.4 0.0 0.011 14.7 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.14 KXL49190.1 - 0.0085 15.5 0.0 0.035 13.5 0.0 1.8 1 1 0 1 1 1 1 Tellurite resistance protein TehB tRNA_U5-meth_tr PF05958.11 KXL49190.1 - 0.015 14.3 0.0 0.018 14.0 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_PK PF05891.12 KXL49190.1 - 0.019 14.5 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase TRM13 PF05206.14 KXL49190.1 - 0.035 13.6 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase TRM13 Methyltransf_18 PF12847.7 KXL49190.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain AdoMet_MTase PF07757.13 KXL49190.1 - 0.19 12.1 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Methyltransf_4 PF02390.17 KXL49190.1 - 0.2 11.1 0.0 4.8 6.6 0.0 2.3 2 1 0 2 2 2 0 Putative methyltransferase Bmt2 PF11968.8 KXL49190.1 - 0.23 11.3 0.0 2.8 7.7 0.0 2.4 3 0 0 3 3 3 0 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Abhydrolase_1 PF00561.20 KXL49191.1 - 6.4e-22 78.4 0.1 1.6e-15 57.4 0.1 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXL49191.1 - 7.9e-19 69.1 0.0 9.4e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXL49191.1 - 7.3e-17 61.4 0.3 9.9e-16 57.7 0.3 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KXL49191.1 - 0.00012 20.9 0.0 0.14 10.8 0.0 2.1 2 0 0 2 2 2 2 Ndr family Peptidase_S9 PF00326.21 KXL49191.1 - 0.0036 16.8 0.2 0.02 14.4 0.1 2.2 3 0 0 3 3 3 1 Prolyl oligopeptidase family AXE1 PF05448.12 KXL49191.1 - 0.022 13.5 0.2 0.08 11.6 0.1 1.8 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydro_lipase PF04083.16 KXL49191.1 - 0.098 12.2 0.1 0.28 10.8 0.1 1.7 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Esterase PF00756.20 KXL49191.1 - 0.1 12.2 0.2 0.25 11.0 0.2 1.7 1 1 0 1 1 1 0 Putative esterase Peptidase_S15 PF02129.18 KXL49191.1 - 0.1 12.1 0.0 1.6 8.2 0.0 2.1 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) UPF0227 PF05728.12 KXL49191.1 - 0.13 12.2 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) SLT_2 PF13406.6 KXL49192.1 - 0.073 12.3 0.0 7.8 5.6 0.0 2.8 1 1 1 3 3 3 0 Transglycosylase SLT domain YIF1 PF03878.15 KXL49193.1 - 1.2e-99 332.7 2.0 1.5e-99 332.4 2.0 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 KXL49193.1 - 0.24 11.1 14.7 0.091 12.5 11.7 1.7 1 1 1 2 2 2 0 Yip1 domain DNA_methylase PF00145.17 KXL49194.1 - 4.5e-12 46.0 0.0 6.8e-06 25.7 0.0 2.1 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase MNSV_P7B PF06692.11 KXL49195.1 - 0.16 12.0 0.3 37 4.4 0.0 2.9 2 1 1 3 3 3 0 Melon necrotic spot virus P7B protein GATase_6 PF13522.6 KXL49196.1 - 3.1e-15 56.5 0.0 8.9e-15 55.1 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KXL49196.1 - 1.3e-12 47.7 0.0 3.4e-12 46.4 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KXL49196.1 - 3.6e-07 29.8 0.0 1.1e-06 28.3 0.0 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 KXL49196.1 - 0.0028 16.6 0.0 0.0046 15.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II TRP PF06011.12 KXL49197.1 - 2.5e-125 418.6 14.8 3.3e-125 418.2 14.8 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KXL49197.1 - 5.9e-40 136.9 0.0 9.6e-40 136.2 0.0 1.4 1 0 0 1 1 1 1 ML-like domain Conotoxin_I2 PF17557.2 KXL49198.1 - 2 8.6 5.7 20 5.4 0.4 2.9 3 0 0 3 3 3 0 I2-superfamily conotoxins HATPase_c PF02518.26 KXL49200.1 - 5.6e-22 78.4 0.0 1.3e-21 77.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXL49200.1 - 2.4e-18 66.3 0.0 2.5e-17 63.0 0.0 2.6 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KXL49200.1 - 1.4e-11 44.3 0.0 2.9e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain POB3_N PF17292.2 KXL49201.1 - 5.6e-30 103.6 0.1 4.6e-28 97.5 0.0 2.6 2 0 0 2 2 2 1 POB3-like N-terminal PH domain Rtt106 PF08512.12 KXL49201.1 - 1.4e-27 95.9 0.0 6.7e-26 90.5 0.0 3.1 4 0 0 4 4 4 1 Histone chaperone Rttp106-like SSrecog PF03531.14 KXL49201.1 - 2.1e-27 94.8 2.5 2.7e-27 94.5 0.0 2.6 3 0 0 3 3 3 1 Structure-specific recognition protein (SSRP1) Acetone_carb_G PF08882.11 KXL49202.1 - 0.17 12.1 0.3 3.4 7.9 0.0 2.5 2 0 0 2 2 2 0 Acetone carboxylase gamma subunit Transp_cyt_pur PF02133.15 KXL49203.1 - 8.4e-85 285.2 41.6 1e-84 284.9 41.6 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PhyH PF05721.13 KXL49204.1 - 2.6e-18 67.1 0.0 3.3e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) TBPIP PF07106.13 KXL49204.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain adh_short PF00106.25 KXL49206.1 - 4.8e-46 156.7 0.5 6.3e-46 156.3 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL49206.1 - 1.5e-31 109.8 0.1 1.9e-31 109.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KXL49206.1 - 0.003 17.0 0.0 0.021 14.2 0.0 2.0 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KXL49206.1 - 0.0059 16.1 0.2 0.011 15.2 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KXL49206.1 - 0.021 14.4 0.1 0.042 13.4 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family ADH_zinc_N PF00107.26 KXL49206.1 - 0.086 12.8 0.1 1.1 9.2 0.1 2.2 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Raf1_HTH PF18579.1 KXL49207.1 - 0.048 13.4 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain Ribosomal_S20p PF01649.18 KXL49207.1 - 0.27 11.9 2.5 0.78 10.4 2.5 1.7 1 0 0 1 1 1 0 Ribosomal protein S20 DUF3439 PF11921.8 KXL49207.1 - 1.2 9.2 8.3 30 4.6 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) Tropomyosin_1 PF12718.7 KXL49207.1 - 1.4 9.1 29.0 1.3 9.2 22.3 2.6 2 1 0 2 2 2 0 Tropomyosin like Laminin_II PF06009.12 KXL49207.1 - 1.7 8.7 12.8 14 5.7 0.1 2.6 2 0 0 2 2 2 0 Laminin Domain II ATG16 PF08614.11 KXL49207.1 - 1.7 8.8 27.9 0.47 10.7 15.3 3.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 KXL49207.1 - 1.7 8.7 8.6 24 5.0 5.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) XLF PF09302.11 KXL49207.1 - 4.6 7.4 10.2 15 5.7 0.0 2.8 2 1 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Snapin_Pallidin PF14712.6 KXL49207.1 - 4.7 7.7 14.4 3.7 8.1 5.2 3.3 2 1 1 3 3 3 0 Snapin/Pallidin DivIC PF04977.15 KXL49207.1 - 4.8 7.0 15.5 4.9 7.0 0.2 3.3 2 1 1 3 3 3 0 Septum formation initiator Uso1_p115_C PF04871.13 KXL49207.1 - 6.4 7.2 27.0 1.2 9.5 20.1 2.3 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region WDCP PF15390.6 KXL49207.1 - 8.6 4.6 13.7 1.6 7.0 9.5 1.6 1 1 1 2 2 2 0 WD repeat and coiled-coil-containing protein family Carb_bind PF10645.9 KXL49209.1 - 0.0039 17.4 5.4 0.014 15.6 3.6 2.3 2 0 0 2 2 2 1 Carbohydrate binding AAA PF00004.29 KXL49210.1 - 5.3e-20 72.2 0.0 4.8e-10 40.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 KXL49210.1 - 1.4e-16 61.0 0.0 5.2e-16 59.2 0.0 1.9 2 0 0 2 2 2 1 BCS1 N terminal RuvB_N PF05496.12 KXL49210.1 - 0.0026 17.5 0.0 0.0051 16.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KXL49210.1 - 0.0059 16.6 0.4 0.057 13.4 0.1 2.9 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXL49210.1 - 0.032 14.6 0.0 0.13 12.7 0.0 2.2 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 KXL49210.1 - 0.047 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Parvo_NS1 PF01057.17 KXL49210.1 - 0.092 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TIP49 PF06068.13 KXL49210.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain IPT PF01745.16 KXL49210.1 - 0.18 11.2 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase AAA_11 PF13086.6 KXL49210.1 - 0.22 11.2 1.5 0.36 10.6 0.0 2.0 2 1 0 2 2 2 0 AAA domain Hydin_ADK PF17213.3 KXL49210.1 - 5.3 7.3 6.4 2.2 8.5 0.0 2.8 2 1 1 3 3 3 0 Hydin Adenylate kinase-like domain Trehalase PF01204.18 KXL49211.1 - 0.00086 18.2 0.0 0.0012 17.7 0.0 1.2 1 0 0 1 1 1 1 Trehalase Glyco_hydro_63 PF03200.16 KXL49211.1 - 0.027 13.2 1.3 1.7 7.3 0.0 2.8 2 1 1 3 3 3 0 Glycosyl hydrolase family 63 C-terminal domain DUF4032 PF13224.6 KXL49211.1 - 0.12 12.2 1.0 0.34 10.8 1.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4032) A_deaminase PF00962.22 KXL49213.1 - 2.1e-49 168.7 0.0 6.1e-49 167.1 0.0 1.6 1 1 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_3 PF07969.11 KXL49213.1 - 0.0072 15.8 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family KIX PF02172.16 KXL49213.1 - 0.12 12.7 0.2 0.26 11.6 0.2 1.5 1 0 0 1 1 1 0 KIX domain P-mevalo_kinase PF04275.14 KXL49214.1 - 2.2e-20 72.7 0.0 4e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 Phosphomevalonate kinase Pribosyltran PF00156.27 KXL49214.1 - 3.6e-19 68.8 0.0 7.6e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain FAD_binding_4 PF01565.23 KXL49214.1 - 6.1e-15 55.2 0.6 1.2e-14 54.2 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain PRTase_2 PF15609.6 KXL49214.1 - 5.7e-05 22.7 0.1 0.0011 18.5 0.0 2.6 3 0 0 3 3 3 1 Phosphoribosyl transferase UPRTase PF14681.6 KXL49214.1 - 0.00047 19.7 0.0 0.0061 16.0 0.0 2.3 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase T2SSE PF00437.20 KXL49214.1 - 0.23 10.5 0.0 1 8.4 0.0 2.0 3 0 0 3 3 3 0 Type II/IV secretion system protein ERO1 PF04137.15 KXL49215.1 - 4.9e-131 437.1 0.0 6.3e-131 436.8 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) UQ_con PF00179.26 KXL49216.1 - 4.1e-24 84.8 0.0 4.7e-24 84.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXL49216.1 - 0.0008 19.1 0.0 0.0021 17.7 0.0 1.8 1 1 1 2 2 2 1 Prokaryotic E2 family B Pkinase PF00069.25 KXL49217.1 - 1.9e-66 224.1 0.0 3.1e-66 223.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL49217.1 - 8e-34 117.1 0.0 1.4e-33 116.3 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KXL49217.1 - 6.8e-05 22.3 0.0 8.8e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXL49217.1 - 0.0023 17.3 0.0 0.0061 15.9 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TetR_C_27 PF17935.1 KXL49217.1 - 0.025 14.6 0.0 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain FTA2 PF13095.6 KXL49217.1 - 0.11 12.1 0.1 5.6 6.5 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Cupin_2 PF07883.11 KXL49218.1 - 2.1e-09 37.0 0.2 2.9e-09 36.5 0.2 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KXL49218.1 - 0.0006 19.5 0.0 0.00068 19.3 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.7 KXL49218.1 - 0.0019 18.0 0.1 0.0024 17.6 0.1 1.2 1 0 0 1 1 1 1 Cupin NAD_binding_10 PF13460.6 KXL49219.1 - 0.0086 16.0 0.0 0.017 15.0 0.0 1.4 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KXL49219.1 - 0.097 12.1 0.0 0.14 11.6 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family zf_CCCH_4 PF18345.1 KXL49220.1 - 4.4e-16 58.3 37.9 2.7e-05 24.1 3.6 5.7 6 0 0 6 6 6 5 Zinc finger domain zf-CCCH PF00642.24 KXL49220.1 - 2.7e-15 55.8 37.1 8.5e-05 22.4 0.6 5.6 6 0 0 6 6 6 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KXL49220.1 - 1.3e-10 41.9 28.2 0.00041 21.0 0.2 5.0 1 1 4 5 5 5 4 Torus domain zf-CCCH_4 PF18044.1 KXL49220.1 - 0.0013 18.5 41.8 0.16 11.8 1.1 6.3 6 1 0 6 6 6 4 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KXL49220.1 - 0.13 12.5 11.0 1.4 9.2 1.5 2.8 1 1 2 3 3 3 0 Zinc-finger containing family DUF1771 PF08590.10 KXL49221.1 - 4.9e-14 52.5 10.7 1.2e-13 51.2 10.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) zf-CCCH PF00642.24 KXL49221.1 - 1e-08 34.9 2.2 0.0006 19.7 0.1 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KXL49221.1 - 9.3e-07 28.7 10.1 0.0004 20.4 2.3 2.9 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH_2 PF14608.6 KXL49221.1 - 0.00012 22.4 6.2 0.094 13.2 0.4 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Smr PF01713.21 KXL49221.1 - 0.00014 22.2 0.1 0.00045 20.5 0.1 1.9 1 0 0 1 1 1 1 Smr domain zf-CCCH_4 PF18044.1 KXL49221.1 - 0.00068 19.4 9.4 0.0019 18.0 0.7 2.9 2 1 0 2 2 2 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KXL49221.1 - 0.0036 17.5 3.0 0.47 10.7 0.1 2.5 1 1 1 2 2 2 2 Zinc-finger containing family SSP160 PF06933.11 KXL49221.1 - 0.0058 14.9 13.9 0.0083 14.4 13.9 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 zf-C3H1 PF10650.9 KXL49221.1 - 0.18 11.6 0.8 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 Putative zinc-finger domain Spt20 PF12090.8 KXL49221.1 - 1.6 8.3 26.4 0.041 13.5 15.8 2.2 2 0 0 2 2 2 0 Spt20 family RVT_2 PF07727.14 KXL49222.1 - 1.1e-52 179.1 0.1 1.6e-52 178.6 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KXL49222.1 - 0.00066 19.9 0.0 0.0016 18.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain MFS_1 PF07690.16 KXL49223.1 - 4e-18 65.5 31.9 2.5e-11 43.1 4.8 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 KXL49223.1 - 2e-09 36.6 10.1 5.6e-07 28.5 3.6 3.9 4 0 0 4 4 4 2 MFS/sugar transport protein ATG22 PF11700.8 KXL49223.1 - 0.013 14.1 5.9 0.39 9.3 0.0 2.7 3 1 0 3 3 3 0 Vacuole effluxer Atg22 like DUF5434 PF17502.2 KXL49223.1 - 0.095 12.7 1.1 0.24 11.4 1.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5434) DUF1772 PF08592.11 KXL49223.1 - 0.13 12.5 0.1 0.13 12.5 0.1 4.8 4 2 0 4 4 4 0 Domain of unknown function (DUF1772) NUDIX PF00293.28 KXL49224.1 - 2.2e-06 27.7 0.0 3.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 KXL49224.1 - 0.0057 16.6 0.0 0.0086 16.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) Tom37 PF10568.9 KXL49225.1 - 5e-14 52.7 0.0 1e-13 51.7 0.0 1.6 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 KXL49225.1 - 7.1e-07 28.9 0.0 1.5e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_transf_41 PF13844.6 KXL49227.1 - 1.5e-104 350.1 0.0 2.6e-52 177.8 0.0 3.1 2 1 1 3 3 3 2 Glycosyl transferase family 41 TPR_1 PF00515.28 KXL49227.1 - 1e-16 59.9 5.9 5.9e-06 25.9 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXL49227.1 - 1.4e-15 56.1 6.2 0.019 15.0 0.0 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 KXL49227.1 - 1.9e-13 49.8 3.5 0.027 14.8 0.3 5.3 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 KXL49227.1 - 3.1e-13 48.8 3.8 0.00012 22.0 0.1 5.6 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXL49227.1 - 4.9e-12 45.3 13.8 1.1e-05 25.1 0.1 4.8 3 1 2 5 5 5 3 TPR repeat TPR_19 PF14559.6 KXL49227.1 - 6e-12 45.9 4.5 0.00022 21.7 0.0 3.7 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KXL49227.1 - 1.5e-09 38.0 5.6 0.02 15.2 0.3 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXL49227.1 - 5.1e-09 36.2 5.6 0.078 13.8 0.0 5.9 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXL49227.1 - 3.7e-08 32.9 1.0 0.4 10.8 0.1 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXL49227.1 - 5.4e-08 33.4 4.9 1.7 9.3 0.0 4.5 3 1 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KXL49227.1 - 2.7e-07 30.2 11.7 0.016 15.0 0.1 5.5 6 0 0 6 6 6 3 Tetratricopeptide repeat BTAD PF03704.17 KXL49227.1 - 0.0011 19.4 2.5 0.36 11.3 0.0 3.6 4 0 0 4 4 4 1 Bacterial transcriptional activator domain TPR_9 PF13371.6 KXL49227.1 - 0.076 13.2 6.3 0.28 11.4 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXL49227.1 - 0.18 12.5 1.4 62 4.6 0.1 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat HTH_50 PF18024.1 KXL49229.1 - 0.00042 19.9 0.1 0.00074 19.1 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain SpoIIID PF12116.8 KXL49229.1 - 0.039 14.0 0.1 0.044 13.9 0.1 1.3 1 0 0 1 1 1 0 Stage III sporulation protein D VBS PF08913.10 KXL49229.1 - 0.1 13.1 0.1 0.11 12.9 0.1 1.1 1 0 0 1 1 1 0 Vinculin Binding Site FAD_binding_3 PF01494.19 KXL49230.1 - 7.4e-06 25.4 0.0 0.085 12.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXL49230.1 - 0.00018 21.7 0.0 0.00035 20.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXL49230.1 - 0.00078 19.1 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXL49230.1 - 0.17 12.4 0.0 1 9.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4083 PF13314.6 KXL49231.1 - 0.11 12.4 2.2 0.12 12.4 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) GATA PF00320.27 KXL49232.1 - 7.8e-33 111.8 16.4 1.3e-16 59.8 4.5 2.2 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KXL49232.1 - 7e-07 28.7 5.1 0.0075 15.8 0.4 2.2 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 KXL49232.1 - 1.9e-06 27.9 1.7 0.011 15.8 0.1 2.3 2 0 0 2 2 2 2 Zinc ribbon domain TDP43_N PF18694.1 KXL49232.1 - 2.1e-06 27.5 0.3 0.06 13.2 0.1 2.2 2 0 0 2 2 2 2 Transactive response DNA-binding protein N-terminal domain ArfGap PF01412.18 KXL49232.1 - 4.4e-06 26.8 2.9 0.0072 16.4 0.1 2.1 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf OrfB_Zn_ribbon PF07282.11 KXL49232.1 - 5.6e-05 23.0 6.3 0.0076 16.2 0.6 2.2 1 1 1 2 2 2 2 Putative transposase DNA-binding domain Auto_anti-p27 PF06677.12 KXL49232.1 - 0.00012 22.2 5.9 0.029 14.5 0.5 2.3 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 KXL49232.1 - 0.00014 21.8 8.7 0.006 16.6 9.3 2.7 1 1 2 3 3 3 3 Double zinc ribbon eIF-5_eIF-2B PF01873.17 KXL49232.1 - 0.00058 19.7 5.3 0.21 11.5 0.6 2.2 2 0 0 2 2 2 2 Domain found in IF2B/IF5 zf-ribbon_3 PF13248.6 KXL49232.1 - 0.0018 17.6 11.0 0.9 9.0 0.2 4.2 4 0 0 4 4 4 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 KXL49232.1 - 0.0028 18.4 4.4 1.5 9.6 5.8 3.0 1 1 2 3 3 3 1 zinc-ribbon family zf-RRPl_C4 PF17026.5 KXL49232.1 - 0.0036 17.4 1.2 0.31 11.2 0.2 2.2 1 1 1 2 2 2 1 Putative ribonucleoprotein zinc-finger pf C4 type Ribosomal_L32p PF01783.23 KXL49232.1 - 0.0043 17.3 14.5 0.82 10.0 4.3 4.1 2 2 0 2 2 2 1 Ribosomal L32p protein family zf-Sec23_Sec24 PF04810.15 KXL49232.1 - 0.0097 15.9 0.7 0.0097 15.9 0.7 2.5 2 1 0 2 2 2 1 Sec23/Sec24 zinc finger Rubredoxin_2 PF18073.1 KXL49232.1 - 0.012 15.3 8.7 9.9 6.0 0.2 4.2 4 0 0 4 4 4 0 Rubredoxin metal binding domain A2L_zn_ribbon PF08792.10 KXL49232.1 - 0.023 14.4 6.7 10 5.9 0.0 4.0 4 0 0 4 4 4 0 A2L zinc ribbon domain HypA PF01155.19 KXL49232.1 - 0.04 13.9 5.2 0.4 10.7 0.4 2.4 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-CHY PF05495.12 KXL49232.1 - 0.081 13.4 4.2 0.39 11.2 1.2 2.4 1 1 1 2 2 2 0 CHY zinc finger Elf1 PF05129.13 KXL49232.1 - 0.1 12.7 6.7 4.6 7.4 0.4 3.1 2 2 0 2 2 2 0 Transcription elongation factor Elf1 like zinc_ribbon_2 PF13240.6 KXL49232.1 - 0.35 10.7 14.2 2.9 7.7 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon domain zf-C2H2_3 PF13878.6 KXL49232.1 - 0.35 10.7 11.9 15 5.5 0.1 4.1 3 1 1 4 4 4 0 zinc-finger of acetyl-transferase ESCO Integrase_Zn PF02022.19 KXL49232.1 - 0.75 9.8 0.1 0.75 9.8 0.1 3.3 3 0 0 3 3 3 0 Integrase Zinc binding domain Rpr2 PF04032.16 KXL49232.1 - 0.76 10.1 7.7 48 4.3 5.1 3.1 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Nudix_N_2 PF14803.6 KXL49232.1 - 0.81 9.7 13.8 0.85 9.6 2.5 3.3 2 1 0 2 2 2 0 Nudix N-terminal zinc_ribbon_4 PF13717.6 KXL49232.1 - 0.83 9.6 10.0 2.1 8.4 0.1 3.9 4 0 0 4 4 4 0 zinc-ribbon domain zf-RING_7 PF02591.15 KXL49232.1 - 0.94 9.7 0.1 0.94 9.7 0.1 3.4 4 0 0 4 4 4 0 C4-type zinc ribbon domain zf_UBZ PF18439.1 KXL49232.1 - 1.2 8.7 0.1 1.2 8.7 0.1 3.3 3 1 1 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-RING_5 PF14634.6 KXL49232.1 - 1.6 8.8 8.4 7.6 6.6 0.2 3.4 3 1 0 3 3 3 0 zinc-RING finger domain Prim_Zn_Ribbon PF08273.12 KXL49232.1 - 3.9 7.8 16.0 4.7 7.6 3.9 3.4 2 2 1 3 3 3 0 Zinc-binding domain of primase-helicase zf-C4_ClpX PF06689.13 KXL49232.1 - 8 6.4 10.0 0.57 10.1 0.8 2.8 3 1 0 3 3 3 0 ClpX C4-type zinc finger Prok-RING_1 PF14446.6 KXL49232.1 - 8.3 6.4 12.3 14 5.7 0.3 3.6 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 COPI_assoc PF08507.10 KXL49234.1 - 1.5e-31 109.2 5.7 1.6e-31 109.1 5.7 1.0 1 0 0 1 1 1 1 COPI associated protein CBP_BcsF PF11120.8 KXL49234.1 - 0.41 10.8 0.2 0.41 10.8 0.2 2.3 3 0 0 3 3 3 0 Cellulose biosynthesis protein BcsF DUF3096 PF11295.8 KXL49234.1 - 0.6 9.8 8.4 0.46 10.2 0.9 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3096) YtpI PF14007.6 KXL49234.1 - 2.8 8.1 11.2 0.46 10.7 7.1 1.8 1 1 1 2 2 2 0 YtpI-like protein DUF2892 PF11127.8 KXL49234.1 - 3.7 7.6 10.6 1.3 9.1 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) DAO PF01266.24 KXL49237.1 - 8.5e-36 124.2 1.4 9.7e-36 124.1 1.4 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXL49237.1 - 0.00058 19.1 0.0 0.00082 18.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXL49237.1 - 0.04 14.1 0.1 0.11 12.8 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXL49237.1 - 0.04 13.1 0.2 0.04 13.1 0.2 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.14 KXL49237.1 - 0.062 12.5 0.4 0.15 11.3 0.2 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXL49237.1 - 0.09 11.6 0.5 2.8 6.7 0.3 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox PF00070.27 KXL49237.1 - 0.16 12.6 0.0 0.64 10.6 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase OTU PF02338.19 KXL49239.1 - 1e-09 39.0 0.0 2.5e-09 37.7 0.0 1.6 1 1 0 1 1 1 1 OTU-like cysteine protease CUE PF02845.16 KXL49239.1 - 0.009 15.7 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 CUE domain Peptidase_C65 PF10275.9 KXL49239.1 - 0.019 14.4 0.3 7.5 5.9 0.5 2.7 2 1 0 2 2 2 0 Peptidase C65 Otubain Rib_5-P_isom_A PF06026.14 KXL49240.1 - 2.6e-42 144.4 0.0 4e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) ThiF PF00899.21 KXL49241.1 - 3.6e-13 49.4 0.0 1.7e-12 47.2 0.0 1.9 1 1 0 1 1 1 1 ThiF family PNTB PF02233.16 KXL49242.1 - 2.7e-170 567.2 26.2 2.7e-170 567.2 26.2 2.1 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 KXL49242.1 - 2.1e-75 252.7 0.1 9.8e-75 250.5 0.2 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 KXL49242.1 - 5.8e-38 130.3 0.0 2.4e-37 128.3 0.0 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 KXL49242.1 - 4.4e-31 107.2 3.2 4.4e-31 107.2 3.2 4.9 4 2 2 6 6 6 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 KXL49242.1 - 0.0036 16.7 0.4 0.37 10.1 0.1 2.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KXL49242.1 - 0.016 14.5 0.1 0.044 13.0 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TPP_enzyme_M PF00205.22 KXL49242.1 - 0.018 14.8 0.2 0.1 12.3 0.1 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain CP_ATPgrasp_1 PF04174.13 KXL49242.1 - 0.08 12.0 0.4 0.16 11.0 0.0 1.6 2 0 0 2 2 2 0 A circularly permuted ATPgrasp ADH_zinc_N PF00107.26 KXL49242.1 - 0.11 12.5 2.2 0.26 11.3 0.1 2.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase GIDA PF01134.22 KXL49242.1 - 0.11 11.5 1.3 0.19 10.8 1.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KXL49242.1 - 0.15 11.1 3.8 1.2 8.2 2.6 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 KXL49242.1 - 0.7 10.2 4.7 0.28 11.5 0.6 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Nipped-B_C PF12830.7 KXL49243.1 - 1.4e-52 178.4 2.2 3.6e-50 170.6 0.1 4.1 4 0 0 4 4 4 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 KXL49243.1 - 5.4e-06 26.6 0.2 2e-05 24.8 0.2 2.1 1 0 0 1 1 1 1 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.20 KXL49243.1 - 0.00014 20.5 4.0 0.0051 15.4 0.8 3.0 2 1 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 KXL49243.1 - 0.00016 21.7 3.8 0.28 11.2 0.3 3.7 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KXL49243.1 - 0.0011 19.0 6.3 0.3 11.4 0.1 5.6 6 1 0 6 6 6 1 HEAT repeat Bul1_N PF04425.12 KXL49243.1 - 0.0064 15.3 0.5 0.013 14.3 0.5 1.5 1 0 0 1 1 1 1 Bul1 N terminus MMS19_C PF12460.8 KXL49243.1 - 0.43 9.6 6.3 0.17 11.0 0.8 2.9 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal TFIIS_C PF01096.18 KXL49244.1 - 1.2e-14 53.8 6.0 1.2e-14 53.8 6.0 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KXL49244.1 - 1.7e-06 27.8 12.7 5.9e-06 26.0 1.3 2.9 3 0 0 3 3 3 2 RNA polymerases M/15 Kd subunit DZR PF12773.7 KXL49244.1 - 6e-05 23.0 8.3 0.032 14.3 0.4 2.5 2 1 0 2 2 2 2 Double zinc ribbon IBR PF01485.21 KXL49244.1 - 0.00052 20.2 7.7 0.24 11.7 2.4 2.2 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain zinc_ribbon_2 PF13240.6 KXL49244.1 - 0.0024 17.6 14.8 1.8 8.4 0.3 4.3 4 0 0 4 4 4 3 zinc-ribbon domain UCH_1 PF13423.6 KXL49244.1 - 0.0091 15.6 4.3 0.01 15.4 4.3 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Zn_ribbon_recom PF13408.6 KXL49244.1 - 0.14 12.7 0.1 0.14 12.7 0.1 2.5 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain UPF0547 PF10571.9 KXL49244.1 - 0.34 11.0 0.5 0.34 11.0 0.5 3.6 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 Baculo_LEF5_C PF11792.8 KXL49244.1 - 0.63 9.8 0.0 0.63 9.8 0.0 3.1 3 1 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain zf-RING_7 PF02591.15 KXL49244.1 - 1 9.6 0.0 1 9.6 0.0 3.6 4 1 0 4 4 4 0 C4-type zinc ribbon domain A2L_zn_ribbon PF08792.10 KXL49244.1 - 1.5 8.6 15.8 6.9 6.5 0.2 4.2 4 0 0 4 4 4 0 A2L zinc ribbon domain zf-ribbon_3 PF13248.6 KXL49244.1 - 1.6 8.2 15.6 2.5 7.7 0.4 4.2 4 0 0 4 4 4 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 KXL49244.1 - 1.8 8.1 16.8 3.3 7.3 0.2 3.9 2 2 2 4 4 4 0 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.7 KXL49244.1 - 1.9 8.6 11.9 14 5.8 0.1 3.0 2 1 0 2 2 2 0 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 KXL49244.1 - 4.4 7.3 13.6 14 5.7 5.1 2.8 2 2 1 3 3 3 0 Putative transposase DNA-binding domain CpXC PF14353.6 KXL49244.1 - 6.9 6.7 10.9 2.4 8.2 0.2 3.3 1 1 2 3 3 3 0 CpXC protein HEAT_2 PF13646.6 KXL49245.1 - 4.7e-28 97.4 1.7 2.8e-13 50.1 0.4 3.1 2 2 1 3 3 3 2 HEAT repeats HEAT_PBS PF03130.16 KXL49245.1 - 3.2e-20 70.7 2.0 0.0025 18.3 0.3 6.1 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.22 KXL49245.1 - 7e-05 22.8 5.6 1.6 9.2 0.0 6.2 8 0 0 8 8 8 1 HEAT repeat HEAT_EZ PF13513.6 KXL49245.1 - 0.0021 18.5 2.8 1.3 9.6 0.1 4.7 4 1 1 5 5 5 1 HEAT-like repeat RuvA_C PF07499.13 KXL49245.1 - 0.16 12.5 0.7 8.9 6.9 0.0 3.3 3 0 0 3 3 3 0 RuvA, C-terminal domain TOM13 PF08219.11 KXL49245.1 - 0.18 11.8 0.0 1 9.4 0.0 2.1 2 0 0 2 2 2 0 Outer membrane protein TOM13 PUB_1 PF18486.1 KXL49245.1 - 0.23 11.4 2.3 0.43 10.5 0.1 2.5 3 0 0 3 3 3 0 PNGase/UBA- or UBX-containing domain DUF1681 PF07933.14 KXL49246.1 - 5.7e-53 178.6 0.0 7.3e-53 178.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) She9_MDM33 PF05546.11 KXL49247.1 - 2.2e-54 184.3 4.3 3.2e-54 183.8 4.3 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family Muted PF14942.6 KXL49247.1 - 0.036 14.4 2.8 0.14 12.5 0.1 2.3 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein YscO-like PF16789.5 KXL49247.1 - 0.12 12.4 11.3 1.7 8.6 0.8 2.4 1 1 1 2 2 2 0 YscO-like protein YscO PF07321.12 KXL49247.1 - 0.17 11.9 9.2 2 8.4 0.8 2.3 2 0 0 2 2 2 0 Type III secretion protein YscO SNARE PF05739.19 KXL49247.1 - 7.7 6.6 6.4 19 5.3 1.4 2.5 2 0 0 2 2 2 0 SNARE domain HAD PF12710.7 KXL49248.1 - 1.4e-24 87.6 0.0 1.8e-24 87.2 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KXL49248.1 - 0.00011 21.7 0.0 0.00065 19.2 0.0 1.9 1 1 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.12 KXL49248.1 - 0.043 13.3 0.0 0.22 11.0 0.0 2.0 2 1 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 KXL49248.1 - 0.18 12.0 0.2 7 6.9 0.0 2.9 1 1 2 3 3 3 0 haloacid dehalogenase-like hydrolase Ribosom_S12_S23 PF00164.25 KXL49249.1 - 3.9e-33 113.4 1.3 5.1e-33 113.1 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S12 PF17487.2 KXL49249.1 - 0.068 13.9 0.0 0.14 12.9 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein S12 RNase_T PF00929.24 KXL49251.1 - 1.8e-12 48.1 0.0 3.1e-12 47.3 0.0 1.4 1 1 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 KXL49251.1 - 0.058 13.1 0.0 0.19 11.4 0.0 1.8 1 1 0 1 1 1 0 3'-5' exonuclease MOZ_SAS PF01853.18 KXL49252.1 - 1.1e-81 272.8 0.0 1.7e-81 272.2 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KXL49252.1 - 4.1e-25 87.1 2.8 9.6e-25 86.0 2.8 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 KXL49252.1 - 3.9e-22 77.9 0.0 8.2e-22 76.9 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 KXL49252.1 - 0.00037 20.9 0.0 0.00079 19.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXL49252.1 - 0.0053 17.0 0.0 0.019 15.2 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF1918 PF08940.11 KXL49252.1 - 0.18 11.5 0.0 0.45 10.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) zf-C2H2_4 PF13894.6 KXL49252.1 - 3 8.9 5.3 8.3 7.5 5.3 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger DUF4385 PF14328.6 KXL49253.1 - 1.2e-49 168.1 0.5 1.6e-49 167.7 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4385) Fungal_trans_2 PF11951.8 KXL49254.1 - 6.6e-11 41.6 3.5 2.2e-10 39.9 3.5 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL49254.1 - 8.8e-07 29.0 11.3 1.8e-06 28.0 11.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RACo_C_ter PF14574.6 KXL49254.1 - 0.024 13.7 0.1 2.3 7.2 0.1 2.3 2 0 0 2 2 2 0 C-terminal domain of RACo the ASKHA domain Syja_N PF02383.18 KXL49255.1 - 1.2e-77 261.4 0.0 1.9e-77 260.7 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain MFS_1 PF07690.16 KXL49255.1 - 4e-33 114.8 24.4 4e-33 114.8 24.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Metallophos PF00149.28 KXL49256.1 - 3e-32 112.8 0.0 2.8e-22 80.2 0.0 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase Glyco_hydro_92 PF07971.12 KXL49257.1 - 2.7e-138 461.8 2.3 3.2e-138 461.5 2.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KXL49257.1 - 3.4e-48 164.6 0.1 5.6e-48 163.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain DUF3112 PF11309.8 KXL49258.1 - 1.9e-09 37.3 12.4 1.9e-08 34.0 0.2 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF3112) PHO4 PF01384.20 KXL49258.1 - 0.066 12.2 4.2 0.076 12.0 4.2 1.2 1 0 0 1 1 1 0 Phosphate transporter family ERGIC_N PF13850.6 KXL49258.1 - 0.49 10.8 2.0 0.7 10.3 0.6 2.0 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF4321 PF14209.6 KXL49258.1 - 0.98 9.3 4.9 10 6.1 4.9 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4321) PRIMA1 PF16101.5 KXL49258.1 - 1.2 9.2 3.2 0.55 10.3 0.1 2.0 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Abhydrolase_9_N PF15420.6 KXL49258.1 - 1.6 8.7 5.9 47 3.9 5.9 2.3 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus Acyltransferase PF01553.21 KXL49259.1 - 2.2e-17 62.9 0.0 5.8e-17 61.6 0.0 1.7 1 0 0 1 1 1 1 Acyltransferase zf-C3HC4_3 PF13920.6 KXL49260.1 - 1.1e-08 34.8 11.1 1.9e-08 34.0 11.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXL49260.1 - 0.0021 17.9 10.2 0.0038 17.1 10.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Rab5ip PF07019.12 KXL49260.1 - 1.6 9.3 10.3 1.3 9.6 4.1 3.4 2 1 0 2 2 2 0 Rab5-interacting protein (Rab5ip) F-box PF00646.33 KXL49261.1 - 3.2e-10 39.6 0.0 1.9e-09 37.1 0.0 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KXL49261.1 - 1.7e-09 37.4 0.0 3.5e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like UIM PF02809.20 KXL49261.1 - 3.8 7.7 12.2 12 6.1 0.2 3.9 4 0 0 4 4 4 0 Ubiquitin interaction motif Metallophos PF00149.28 KXL49262.1 - 2.2e-37 129.6 0.5 3.5e-37 128.9 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KXL49262.1 - 0.0013 19.1 0.2 0.0028 18.1 0.2 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 KXL49262.1 - 0.077 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain RNase_H2_suC PF08615.11 KXL49263.1 - 4.1e-28 98.3 0.0 4.8e-28 98.1 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) CMAS PF02353.20 KXL49264.1 - 6.2e-64 215.9 0.0 4.4e-63 213.1 0.0 1.9 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KXL49264.1 - 5.5e-11 43.0 0.0 1.1e-10 42.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL49264.1 - 1.2e-10 41.9 0.0 2.4e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXL49264.1 - 4.7e-09 36.3 0.0 7.5e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL49264.1 - 5.1e-07 29.6 0.0 8e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL49264.1 - 6.5e-06 26.8 0.0 1.5e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 KXL49264.1 - 0.13 12.1 0.0 0.88 9.3 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_3 PF01596.17 KXL49264.1 - 0.18 11.0 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase ProRS-C_1 PF09180.11 KXL49266.1 - 3.4e-21 75.2 0.4 6.7e-21 74.3 0.4 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 KXL49266.1 - 3e-18 66.4 0.0 5.3e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KXL49266.1 - 4.1e-16 58.9 0.0 1.1e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain MACPF PF01823.19 KXL49266.1 - 0.14 12.2 1.5 0.25 11.4 1.5 1.3 1 0 0 1 1 1 0 MAC/Perforin domain RFX_DNA_binding PF02257.15 KXL49267.1 - 0.068 13.8 0.7 0.089 13.4 0.7 1.4 1 1 0 1 1 1 0 RFX DNA-binding domain Ammonium_transp PF00909.21 KXL49270.1 - 6.4e-113 377.5 31.3 7.3e-113 377.3 31.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Clat_adaptor_s PF01217.20 KXL49271.1 - 1.9e-55 186.7 0.8 2.1e-55 186.5 0.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ABC_ATPase PF09818.9 KXL49272.1 - 6.1e-148 493.3 0.0 7.8e-148 493.0 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 KXL49272.1 - 0.014 15.9 0.0 0.02 15.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXL49272.1 - 0.06 13.1 0.3 0.12 12.1 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 KXL49272.1 - 0.19 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Band_7 PF01145.25 KXL49275.1 - 4.7e-30 104.9 3.5 4.7e-30 104.9 3.5 1.6 2 1 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KXL49275.1 - 0.0049 16.6 0.1 0.0093 15.7 0.1 1.5 1 0 0 1 1 1 1 SPFH domain-Band 7 family Kinesin_assoc PF16183.5 KXL49275.1 - 0.37 10.9 3.3 0.97 9.6 3.2 1.8 1 1 0 1 1 1 0 Kinesin-associated DDE_1 PF03184.19 KXL49276.1 - 0.00018 21.2 0.0 0.0002 21.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease PQ-loop PF04193.14 KXL49278.1 - 5.3e-26 90.2 2.0 8.2e-18 63.9 0.8 2.8 2 1 0 2 2 2 2 PQ loop repeat ABC_tran_CTD PF16326.5 KXL49279.1 - 9.2e-05 22.6 1.2 9.2e-05 22.6 1.2 4.9 4 2 1 5 5 5 3 ABC transporter C-terminal domain EzrA PF06160.12 KXL49279.1 - 0.021 13.0 26.2 0.024 12.8 7.3 2.4 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Troponin-I_N PF11636.8 KXL49279.1 - 3.1 7.8 16.2 11 6.1 16.2 2.0 1 0 0 1 1 1 0 Troponin I residues 1-32 FapA PF03961.13 KXL49279.1 - 3.2 6.3 29.3 1.1 7.8 15.6 2.6 1 1 2 3 3 3 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 KXL49279.1 - 3.7 7.7 23.1 0.82 9.9 9.4 3.5 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 KXL49279.1 - 4.1 7.4 5.5 28 4.7 4.0 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus YabA PF06156.13 KXL49279.1 - 5.7 7.6 20.1 0.97 10.1 1.5 3.8 2 1 0 2 2 2 0 Initiation control protein YabA SNF2_N PF00176.23 KXL49280.1 - 4.8e-58 196.6 0.0 7.7e-58 195.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 KXL49280.1 - 3.7e-53 180.4 0.2 1.5e-52 178.4 0.2 1.9 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.31 KXL49280.1 - 4e-15 56.1 0.0 1.3e-14 54.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL49280.1 - 3.4e-06 27.2 0.0 5.5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KXL49280.1 - 0.00038 19.7 0.0 0.0022 17.2 0.0 2.1 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 SPX PF03105.19 KXL49281.1 - 9.2 6.1 13.4 12 5.7 13.4 1.1 1 0 0 1 1 1 0 SPX domain Myb_DNA-binding PF00249.31 KXL49282.1 - 3e-15 56.1 4.9 1.4e-06 28.4 0.2 3.4 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXL49282.1 - 7e-14 51.8 1.2 2e-09 37.5 0.1 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KXL49282.1 - 0.0088 16.4 1.1 0.0088 16.4 1.1 3.0 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain KfrB PF18790.1 KXL49282.1 - 0.083 13.1 0.0 0.39 11.0 0.0 2.2 1 0 0 1 1 1 0 KfrB protein MADF_DNA_bdg PF10545.9 KXL49282.1 - 0.5 10.7 5.8 2 8.8 0.8 2.8 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Acetyltransf_1 PF00583.25 KXL49283.1 - 1.7e-10 41.1 0.0 2.3e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXL49283.1 - 4.9e-08 33.3 0.0 1.3e-07 31.9 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXL49283.1 - 3.9e-05 23.6 0.0 5.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXL49283.1 - 0.0066 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Ppx-GppA PF02541.16 KXL49284.1 - 6.5e-45 153.8 0.0 8.9e-45 153.3 0.0 1.1 1 0 0 1 1 1 1 Ppx/GppA phosphatase family DDR PF08841.10 KXL49284.1 - 0.0016 17.5 0.2 0.0027 16.8 0.2 1.3 1 0 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain WD40 PF00400.32 KXL49285.1 - 1.3e-61 203.0 15.0 1.9e-09 38.0 0.1 8.0 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL49285.1 - 4.7e-26 90.9 0.0 0.00098 19.4 0.0 6.3 2 1 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXL49285.1 - 3.3e-09 36.2 0.1 0.86 8.5 0.0 5.8 3 2 3 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KXL49285.1 - 6.8e-09 35.9 0.0 0.061 13.2 0.0 3.9 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KXL49285.1 - 1.1e-08 34.3 1.4 0.066 11.8 0.0 4.8 2 2 3 5 5 5 2 Nucleoporin Nup120/160 DUF1513 PF07433.11 KXL49285.1 - 0.00023 20.3 0.7 0.59 9.2 0.0 3.7 2 1 2 4 4 4 2 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.16 KXL49285.1 - 0.0011 17.5 0.0 1 7.8 0.0 3.0 2 1 0 3 3 3 1 Cytochrome D1 heme domain PD40 PF07676.12 KXL49285.1 - 0.0015 18.4 1.2 3 7.9 0.0 4.9 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat AP2 PF00847.20 KXL49285.1 - 0.0018 18.5 0.4 0.62 10.4 0.1 2.4 2 0 0 2 2 2 1 AP2 domain PALB2_WD40 PF16756.5 KXL49285.1 - 0.0018 17.2 0.9 0.054 12.4 0.1 2.9 3 1 1 4 4 4 1 Partner and localizer of BRCA2 WD40 domain WD40_like PF17005.5 KXL49285.1 - 0.0028 17.0 0.0 0.009 15.4 0.0 1.9 2 1 0 2 2 2 1 WD40-like domain VID27 PF08553.10 KXL49285.1 - 0.0041 16.2 0.1 2.7 6.9 0.0 3.2 3 1 1 4 4 4 2 VID27 C-terminal WD40-like domain Frtz PF11768.8 KXL49285.1 - 0.016 13.6 0.0 0.037 12.4 0.0 1.5 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Str_synth PF03088.16 KXL49285.1 - 0.032 14.4 0.0 4.4 7.5 0.0 3.3 3 1 0 3 3 3 0 Strictosidine synthase CHAP PF05257.16 KXL49285.1 - 0.12 12.9 0.1 0.3 11.7 0.1 1.8 1 0 0 1 1 1 0 CHAP domain IKI3 PF04762.12 KXL49285.1 - 0.17 9.8 0.0 0.31 9.0 0.0 1.3 1 0 0 1 1 1 0 IKI3 family BNR PF02012.20 KXL49286.1 - 0.0013 18.4 1.4 3 8.2 0.1 3.3 2 0 0 2 2 2 2 BNR/Asp-box repeat BNR_2 PF13088.6 KXL49286.1 - 0.019 14.2 0.0 0.042 13.2 0.0 1.4 1 1 0 1 1 1 0 BNR repeat-like domain NmrA PF05368.13 KXL49287.1 - 1e-06 28.5 0.0 1.5e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family MGDG_synth PF06925.11 KXL49287.1 - 0.11 12.5 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Monogalactosyldiacylglycerol (MGDG) synthase Mad3_BUB1_I PF08311.12 KXL49288.1 - 3.3e-40 136.9 0.0 8.6e-40 135.6 0.0 1.8 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 KXL49288.1 - 5.4e-09 35.8 0.0 1.1e-07 31.5 0.0 2.6 3 0 0 3 3 3 1 Protein kinase domain Mad3_BUB1_II PF08171.11 KXL49288.1 - 5.5e-06 26.4 0.0 5e-05 23.4 0.0 2.5 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 APH PF01636.23 KXL49288.1 - 0.00083 19.4 0.1 0.00083 19.4 0.1 3.3 3 1 1 4 4 4 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KXL49288.1 - 0.0034 16.7 0.0 0.0079 15.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Amino_oxidase PF01593.24 KXL49289.1 - 2.1e-59 202.0 0.0 2.6e-59 201.7 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXL49289.1 - 1.5e-14 53.9 0.1 3.2e-14 52.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Ribonuc_L-PSP PF01042.21 KXL49289.1 - 2.2e-14 53.5 0.0 4.1e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Endoribonuclease L-PSP FAD_oxidored PF12831.7 KXL49289.1 - 5.6e-08 32.6 0.0 7.6e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXL49289.1 - 8.8e-08 31.6 0.5 1.3e-07 31.1 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXL49289.1 - 5.2e-07 29.6 0.5 5.4e-06 26.2 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXL49289.1 - 1.1e-06 28.1 0.1 2.3e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KXL49289.1 - 3.5e-05 24.3 0.1 8.4e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXL49289.1 - 3.8e-05 22.6 0.3 8.5e-05 21.4 0.2 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 KXL49289.1 - 6.8e-05 22.2 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXL49289.1 - 0.00029 20.2 0.4 0.00043 19.6 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KXL49289.1 - 0.00032 19.9 0.3 0.00047 19.3 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KXL49289.1 - 0.00059 19.2 0.1 0.014 14.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXL49289.1 - 0.0006 19.0 0.5 0.0014 17.8 0.2 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KXL49289.1 - 0.0086 15.4 0.1 0.014 14.7 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 KXL49289.1 - 0.31 11.0 0.8 1.5 8.8 0.1 2.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding MFS_1 PF07690.16 KXL49290.1 - 2.7e-09 36.4 26.6 3.8e-09 35.9 26.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KXL49290.1 - 3.5e-07 30.1 3.0 3.5e-07 30.1 3.0 2.2 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 p450 PF00067.22 KXL49291.1 - 6.3e-16 58.2 0.0 3.1e-08 32.8 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 PCI PF01399.27 KXL49292.1 - 1.2e-07 32.2 0.0 4.7e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 PCI domain FA_desaturase PF00487.24 KXL49293.1 - 1.3e-25 90.7 24.9 2.1e-25 90.0 24.9 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KXL49293.1 - 3.2e-10 40.0 0.0 6.1e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF5596 PF18082.1 KXL49293.1 - 0.027 14.3 0.1 0.072 12.9 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5596) DUF4386 PF14329.6 KXL49293.1 - 0.038 13.9 0.4 0.038 13.9 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4386) Ist1 PF03398.14 KXL49294.1 - 2.1e-61 206.6 3.7 2.7e-61 206.3 3.7 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway AAA PF00004.29 KXL49295.1 - 2.9e-16 60.1 0.0 5.9e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 KXL49295.1 - 1.5e-12 47.5 0.0 3.8e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_16 PF13191.6 KXL49295.1 - 4.7e-11 43.4 0.1 4.4e-10 40.2 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain BAH PF01426.18 KXL49295.1 - 1.2e-08 34.8 0.1 4.7e-08 32.9 0.0 2.1 1 1 1 2 2 2 1 BAH domain AAA_22 PF13401.6 KXL49295.1 - 2.9e-08 34.1 0.0 6.1e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXL49295.1 - 0.00068 20.0 0.0 0.0014 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXL49295.1 - 0.0063 16.3 0.1 0.072 12.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KXL49295.1 - 0.0086 16.3 0.8 0.032 14.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KXL49295.1 - 0.02 15.4 0.0 0.11 13.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KXL49295.1 - 0.036 14.5 0.0 0.12 12.8 0.0 1.9 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 KXL49295.1 - 0.039 13.2 0.0 0.12 11.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KXL49295.1 - 0.043 13.5 0.1 0.086 12.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.6 KXL49295.1 - 0.12 11.1 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain ssDBP PF17878.1 KXL49295.1 - 0.12 12.6 0.1 0.27 11.5 0.1 1.5 1 0 0 1 1 1 0 Single-stranded DNA-binding protein NACHT PF05729.12 KXL49295.1 - 0.15 12.0 0.0 0.37 10.7 0.0 1.7 1 1 0 1 1 1 0 NACHT domain PIF1 PF05970.14 KXL49295.1 - 0.16 11.1 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase UNC80 PF15778.5 KXL49296.1 - 0.065 12.8 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 Cation channel complex component UNC80 Asp PF00026.23 KXL49297.1 - 1.3e-06 28.1 0.0 1.3e-06 28.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KXL49297.1 - 0.076 12.8 0.0 0.076 12.8 0.0 1.1 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal DDE_1 PF03184.19 KXL49298.1 - 3e-10 40.1 0.0 3.4e-10 39.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KXL49298.1 - 0.016 15.0 0.0 0.016 15.0 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease rve PF00665.26 KXL49298.1 - 0.12 12.6 0.0 0.14 12.4 0.0 1.1 1 0 0 1 1 1 0 Integrase core domain HTH_psq PF05225.16 KXL49299.1 - 4.7e-05 23.0 0.0 6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain Mga PF05043.13 KXL49299.1 - 0.042 14.4 0.0 0.042 14.4 0.0 1.1 1 0 0 1 1 1 0 Mga helix-turn-helix domain DmpG_comm PF07836.11 KXL49299.1 - 0.071 12.7 0.1 0.085 12.4 0.1 1.1 1 0 0 1 1 1 0 DmpG-like communication domain RWP-RK PF02042.15 KXL49299.1 - 0.12 12.4 0.1 0.19 11.7 0.1 1.4 1 1 0 1 1 1 0 RWP-RK domain INTS5_C PF14838.6 KXL49300.1 - 0.2 10.2 0.1 0.28 9.8 0.1 1.1 1 0 0 1 1 1 0 Integrator complex subunit 5 C-terminus Cdc6_C PF09079.11 KXL49301.1 - 0.0052 16.7 0.0 0.34 10.9 0.0 2.3 2 0 0 2 2 2 2 CDC6, C terminal winged helix domain Meth_synt_2 PF01717.18 KXL49302.1 - 0.00034 20.0 0.0 0.0073 15.6 0.0 2.4 2 1 0 2 2 2 1 Cobalamin-independent synthase, Catalytic domain DUF1989 PF09347.10 KXL49303.1 - 4.4e-37 127.3 0.0 4.4e-31 107.8 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF1989) Fungal_trans PF04082.18 KXL49304.1 - 6.2e-29 100.9 0.6 2.8e-27 95.4 0.0 2.6 3 0 0 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL49304.1 - 2.2e-07 30.9 9.0 3.6e-07 30.2 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DDE_3 PF13358.6 KXL49305.1 - 0.00052 19.8 0.0 0.00075 19.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease PfkB PF00294.24 KXL49307.1 - 3.1e-65 220.5 0.1 3.5e-65 220.3 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Fer2_3 PF13085.6 KXL49307.1 - 0.063 13.3 0.2 0.13 12.2 0.2 1.5 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain AT_hook PF02178.19 KXL49308.1 - 0.002 17.8 1.8 0.0056 16.4 1.8 1.8 1 0 0 1 1 1 1 AT hook motif ERM PF00769.19 KXL49308.1 - 0.043 13.6 18.8 0.054 13.3 18.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF5364 PF17322.2 KXL49308.1 - 0.86 9.9 10.8 3.7 7.8 5.1 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5364) Ribosomal_S13 PF00416.22 KXL49308.1 - 3.7 8.0 5.2 4.3 7.8 0.1 2.7 2 1 1 3 3 3 0 Ribosomal protein S13/S18 Ribosomal_L38e PF01781.18 KXL49309.1 - 0.051 13.7 0.1 0.95 9.6 0.0 2.2 2 0 0 2 2 2 0 Ribosomal L38e protein family DUF1129 PF06570.11 KXL49311.1 - 0.55 9.7 3.6 0.49 9.9 2.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Yip1 PF04893.17 KXL49311.1 - 1 9.1 19.4 0.15 11.7 10.8 2.3 2 0 0 2 2 2 0 Yip1 domain Claudin_2 PF13903.6 KXL49311.1 - 4.6 6.9 13.6 0.075 12.8 2.0 2.5 1 1 2 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Glyco_transf_20 PF00982.21 KXL49313.1 - 3e-198 659.3 0.0 3.4e-198 659.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 KXL49313.1 - 0.019 14.6 0.1 0.047 13.4 0.1 1.6 1 0 0 1 1 1 0 Starch synthase catalytic domain Glyco_trans_1_2 PF13524.6 KXL49313.1 - 0.079 13.4 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KXL49313.1 - 0.17 11.4 0.4 1.9 8.0 0.1 2.4 2 1 0 2 2 2 0 Glycosyl transferases group 1 Ribosomal_S17 PF00366.20 KXL49314.1 - 1.6e-18 66.6 3.3 3.6e-18 65.4 3.3 1.7 1 0 0 1 1 1 1 Ribosomal protein S17 Amidase PF01425.21 KXL49315.1 - 2.1e-85 287.4 0.0 4.7e-85 286.2 0.0 1.5 1 1 0 1 1 1 1 Amidase UPF0180 PF03698.13 KXL49315.1 - 0.14 12.4 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) Zn_clus PF00172.18 KXL49316.1 - 9e-05 22.5 13.9 0.0012 18.9 4.1 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain FXR_C1 PF16096.5 KXL49316.1 - 0.019 15.2 0.0 0.061 13.5 0.0 1.9 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 LicD PF04991.13 KXL49318.1 - 3.2e-22 79.8 15.7 4.3e-17 63.0 6.6 2.8 1 1 2 3 3 3 2 LicD family Amidase PF01425.21 KXL49319.1 - 1.3e-92 311.2 0.0 1.6e-92 310.8 0.0 1.1 1 0 0 1 1 1 1 Amidase MARVEL PF01284.23 KXL49321.1 - 0.032 14.3 15.3 0.061 13.4 10.5 2.0 1 1 1 2 2 2 0 Membrane-associating domain ABC2_membrane_5 PF13346.6 KXL49321.1 - 0.053 13.1 10.1 0.11 12.0 7.6 2.1 2 1 0 2 2 2 0 ABC-2 family transporter protein RSN1_TM PF13967.6 KXL49321.1 - 2 8.2 7.9 0.069 12.9 1.4 2.0 2 1 0 2 2 2 0 Late exocytosis, associated with Golgi transport Zn_ribbon_17 PF17120.5 KXL49322.1 - 3.6e-10 39.3 10.5 7.4e-10 38.3 10.5 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 KXL49322.1 - 7.9e-10 39.2 22.3 1.2e-05 26.0 0.8 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL49322.1 - 1.6e-08 34.8 0.7 0.00053 20.2 0.1 3.4 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXL49322.1 - 2.2e-06 27.7 0.0 0.012 15.5 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A zf-RING_2 PF13639.6 KXL49322.1 - 0.001 19.3 4.0 0.001 19.3 4.0 2.1 2 0 0 2 2 2 1 Ring finger domain PALB2_WD40 PF16756.5 KXL49322.1 - 0.52 9.2 2.7 1.1 8.2 0.2 2.1 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain zf-rbx1 PF12678.7 KXL49322.1 - 1.7 9.0 10.1 8.8 6.7 10.1 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KXL49322.1 - 3.7 7.5 6.8 1.9 8.4 4.2 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_16 PF17034.5 KXL49322.1 - 5.8 7.1 10.4 25 5.1 10.4 1.9 1 1 0 1 1 1 0 Zinc-ribbon like family Forkhead PF00250.18 KXL49323.1 - 2.2e-16 59.9 0.0 4.4e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain CactinC_cactus PF09732.9 KXL49325.1 - 4.1e-58 194.7 5.3 6.8e-58 194.0 5.3 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 KXL49325.1 - 2.1e-53 181.0 5.6 2.1e-53 181.0 5.6 1.6 2 0 0 2 2 2 1 Conserved mid region of cactin SF3A2 PF16835.5 KXL49325.1 - 0.048 14.0 0.0 0.18 12.2 0.0 2.0 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) RAC_head PF16717.5 KXL49325.1 - 0.23 12.4 3.2 3.7 8.6 0.4 2.6 1 1 1 2 2 2 0 Ribosome-associated complex head domain DUF1087 PF06465.13 KXL49325.1 - 5.4 7.1 6.4 0.44 10.6 0.4 2.3 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1087) XLF PF09302.11 KXL49326.1 - 3.9e-42 144.5 0.9 9.9e-42 143.1 0.0 2.0 2 0 0 2 2 2 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component U1snRNP70_N PF12220.8 KXL49326.1 - 3.1 8.5 8.2 1.6 9.4 4.5 2.5 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF1192 PF06698.11 KXL49327.1 - 0.0059 16.6 1.3 0.015 15.3 1.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) DUF1843 PF08898.10 KXL49327.1 - 0.022 15.3 0.1 0.077 13.5 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) Osmo_CC PF08946.10 KXL49327.1 - 0.037 14.3 0.4 0.037 14.3 0.4 2.3 2 0 0 2 2 2 0 Osmosensory transporter coiled coil DUF4618 PF15397.6 KXL49327.1 - 0.13 11.6 0.4 0.44 9.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) G10 PF01125.17 KXL49327.1 - 0.19 11.5 3.0 0.96 9.2 0.4 2.6 3 0 0 3 3 3 0 G10 protein DUF2046 PF09755.9 KXL49327.1 - 0.22 10.7 3.5 0.48 9.6 3.0 1.7 1 1 1 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Peptidase_S30 PF01577.16 KXL49327.1 - 0.32 10.6 1.2 1.3 8.5 1.2 2.0 1 0 0 1 1 1 0 Potyvirus P1 protease WXG100 PF06013.12 KXL49327.1 - 5.4 7.3 8.8 51 4.2 0.1 3.9 4 0 0 4 4 4 0 Proteins of 100 residues with WXG HALZ PF02183.18 KXL49327.1 - 7.6 6.8 6.3 0.7 10.2 0.2 2.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper Glyco_hydro_28 PF00295.17 KXL49328.1 - 6.8e-48 163.4 11.8 1.1e-47 162.7 11.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Ost4 PF10215.9 KXL49329.1 - 0.4 10.6 1.6 17 5.4 0.3 2.2 2 0 0 2 2 2 0 Oligosaccaryltransferase MFS_1 PF07690.16 KXL49330.1 - 1.1e-33 116.7 28.1 8.3e-30 103.9 1.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL49330.1 - 8.1e-06 25.0 6.2 8.1e-06 25.0 6.2 2.7 2 2 0 2 2 2 1 Sugar (and other) transporter Abhydrolase_1 PF00561.20 KXL49331.1 - 4.8e-13 49.4 0.0 2.4e-12 47.1 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXL49331.1 - 4.8e-07 29.3 0.0 4.4e-06 26.2 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXL49331.1 - 1.2e-06 29.2 0.0 3.3e-06 27.9 0.0 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.11 KXL49331.1 - 0.027 13.8 0.0 0.057 12.7 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) zf-CCCH PF00642.24 KXL49332.1 - 3.1e-08 33.3 20.0 3e-07 30.2 2.5 3.1 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 KXL49332.1 - 0.00071 19.3 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 KXL49332.1 - 0.0058 16.6 3.3 0.0058 16.6 3.3 3.3 3 0 0 3 3 3 1 Zinc finger domain Torus PF16131.5 KXL49332.1 - 0.015 16.0 4.2 0.49 11.1 0.2 2.6 3 0 0 3 3 3 0 Torus domain zf-CCCH_3 PF15663.5 KXL49332.1 - 0.017 15.3 2.9 0.017 15.3 2.9 2.4 1 1 0 2 2 2 0 Zinc-finger containing family DUF3899 PF13038.6 KXL49333.1 - 0.2 12.2 2.2 0.27 11.8 1.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3899) HET PF06985.11 KXL49334.1 - 1.6e-28 99.9 0.2 1.6e-28 99.9 0.2 2.6 4 0 0 4 4 4 1 Heterokaryon incompatibility protein (HET) Aldedh PF00171.22 KXL49335.1 - 1.9e-128 428.9 0.8 2.3e-128 428.6 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ank_2 PF12796.7 KXL49336.1 - 2.8e-30 104.7 2.0 5.7e-14 52.5 0.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXL49336.1 - 5.4e-25 87.4 0.2 4.4e-09 36.7 0.0 6.4 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 KXL49336.1 - 9.1e-21 73.3 8.8 0.0014 19.0 0.1 7.2 7 0 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.6 KXL49336.1 - 1.9e-20 70.8 1.4 0.00033 20.9 0.0 7.0 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 KXL49336.1 - 1.4e-16 60.3 2.2 0.0014 18.9 0.1 5.7 2 1 4 6 6 6 3 Ankyrin repeats (many copies) HicA_toxin PF07927.12 KXL49336.1 - 0.011 15.8 0.0 8.6 6.5 0.0 4.5 6 0 0 6 6 6 0 HicA toxin of bacterial toxin-antitoxin, Tht1 PF04163.12 KXL49337.1 - 0.11 11.2 7.4 0.011 14.5 2.1 1.9 2 0 0 2 2 2 0 Tht1-like nuclear fusion protein DUF1013 PF06242.11 KXL49337.1 - 0.19 11.7 0.1 0.19 11.7 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1013) T2SSF PF00482.23 KXL49337.1 - 5.7 6.9 9.0 3.3 7.7 0.1 4.1 3 1 1 4 4 4 0 Type II secretion system (T2SS), protein F ANAPC4_WD40 PF12894.7 KXL49338.1 - 0.14 12.4 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Golgin_A5 PF09787.9 KXL49338.1 - 1.7 8.0 10.2 4.2 6.8 10.2 1.6 1 0 0 1 1 1 0 Golgin subfamily A member 5 PMSR PF01625.21 KXL49339.1 - 1.7e-64 216.7 0.5 2e-64 216.4 0.5 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DUF5545 PF17699.1 KXL49339.1 - 0.089 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5545) Fungal_trans PF04082.18 KXL49340.1 - 2.4e-14 53.0 0.0 4.8e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL49340.1 - 2.9e-06 27.3 13.7 5.5e-06 26.4 13.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5427 PF10310.9 KXL49341.1 - 1.2e-150 502.5 0.0 1.4e-150 502.4 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) Flu_M1_C PF08289.11 KXL49341.1 - 0.15 12.3 0.2 0.48 10.7 0.2 1.8 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain Actino_peptide PF14408.6 KXL49341.1 - 1.3 9.2 0.0 1.3 9.2 0.0 2.6 3 0 0 3 3 3 0 Ribosomally synthesised peptide in actinomycetes CBM26 PF16738.5 KXL49342.1 - 0.12 12.6 0.7 15 5.9 0.0 2.7 2 1 1 3 3 3 0 Starch-binding module 26 Pkinase PF00069.25 KXL49343.1 - 7.8e-67 225.4 0.0 1.8e-66 224.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL49343.1 - 1.2e-31 110.0 0.0 7.6e-30 104.0 0.0 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXL49343.1 - 0.47 9.7 1.6 4.8 6.4 0.0 2.5 3 0 0 3 3 3 0 Kinase-like ADH_N PF08240.12 KXL49344.1 - 3.9e-10 39.6 3.9 2.1e-08 34.0 0.1 2.7 2 1 0 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXL49344.1 - 4.8e-10 39.5 0.2 8.9e-10 38.7 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF295 PF03478.18 KXL49345.1 - 0.14 11.8 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF295) DUF3405 PF11885.8 KXL49346.1 - 4.6e-195 649.1 13.8 2.6e-192 640.0 13.8 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) Podoplanin PF05808.11 KXL49346.1 - 0.017 15.2 0.0 0.027 14.6 0.0 1.2 1 0 0 1 1 1 0 Podoplanin DUF812 PF05667.11 KXL49347.1 - 0.0083 15.1 8.8 0.015 14.2 8.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Tropomyosin_1 PF12718.7 KXL49347.1 - 0.034 14.3 18.4 0.078 13.1 18.4 1.6 1 1 0 1 1 1 0 Tropomyosin like DUF3584 PF12128.8 KXL49347.1 - 0.044 11.3 10.1 0.065 10.8 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4407 PF14362.6 KXL49347.1 - 0.065 12.6 11.9 0.24 10.7 11.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Cortex-I_coil PF09304.10 KXL49347.1 - 0.097 12.9 11.8 0.089 13.0 9.4 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil Macoilin PF09726.9 KXL49347.1 - 0.21 10.1 5.1 0.41 9.1 5.1 1.4 1 0 0 1 1 1 0 Macoilin family AAA_13 PF13166.6 KXL49347.1 - 2.2 6.8 6.5 3.3 6.3 6.5 1.1 1 0 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 KXL49347.1 - 3.1 7.3 9.2 6.3 6.3 9.2 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMF_TATA_bd PF12325.8 KXL49347.1 - 3.9 7.7 17.4 2.2 8.5 5.6 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF745 PF05335.13 KXL49347.1 - 4.2 7.1 15.2 0.14 11.9 3.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF745) FapA PF03961.13 KXL49347.1 - 5 5.6 5.3 7.7 5.0 5.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Cnn_1N PF07989.11 KXL49347.1 - 6.8 6.9 12.0 4.1 7.6 6.6 2.5 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 adh_short PF00106.25 KXL49348.1 - 4.2e-33 114.4 0.0 5.8e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL49348.1 - 4.4e-19 69.0 0.0 6.3e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL49348.1 - 9.8e-07 28.8 0.0 3.3e-06 27.1 0.0 1.8 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXL49348.1 - 0.079 12.8 0.4 0.87 9.5 0.0 2.2 2 0 0 2 2 2 0 NAD(P)H-binding HET PF06985.11 KXL49349.1 - 2.9e-26 92.6 0.0 5.6e-26 91.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PepSY_TM_like_2 PF16357.5 KXL49350.1 - 0.019 14.9 0.1 0.03 14.3 0.1 1.2 1 0 0 1 1 1 0 Putative PepSY_TM-like DUF2561 PF10812.8 KXL49350.1 - 0.037 14.1 1.1 0.042 13.9 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) DUF1180 PF06679.12 KXL49350.1 - 0.099 13.1 0.9 0.26 11.7 0.0 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1180) TMEM154 PF15102.6 KXL49350.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family TMEM156 PF15106.6 KXL49350.1 - 0.12 11.8 1.1 0.2 11.1 1.1 1.2 1 0 0 1 1 1 0 TMEM156 protein family CFEM PF05730.11 KXL49350.1 - 0.84 9.8 8.6 1.3 9.1 8.6 1.3 1 0 0 1 1 1 0 CFEM domain TIL PF01826.17 KXL49350.1 - 2.7 8.3 7.6 6.8 7.0 5.7 2.1 1 1 1 2 2 2 0 Trypsin Inhibitor like cysteine rich domain p450 PF00067.22 KXL49352.1 - 3.6e-67 227.1 0.0 4.9e-67 226.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 KXL49353.1 - 5.2e-10 39.3 7.4 1.1e-09 38.3 7.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Arylsulfotran_2 PF14269.6 KXL49355.1 - 2.4e-50 171.6 0.9 4e-50 170.9 0.9 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXL49355.1 - 3e-16 59.3 1.3 1.2e-14 54.0 1.3 2.7 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Myb_DNA-binding PF00249.31 KXL49359.1 - 0.00024 21.2 2.9 0.00034 20.7 2.9 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF2293 PF10056.9 KXL49360.1 - 0.036 14.3 0.0 0.1 12.8 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2293) Dimer_Tnp_hAT PF05699.14 KXL49361.1 - 1.6e-05 24.6 0.4 8.4e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Asp-B-Hydro_N PF05279.11 KXL49362.1 - 0.88 9.6 17.9 1.3 9.1 17.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region eIF3_subunit PF08597.10 KXL49362.1 - 2.5 8.0 27.5 3.7 7.4 27.5 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF1772 PF08592.11 KXL49363.1 - 1.7e-25 89.9 2.4 2.2e-25 89.6 2.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) CLU PF13236.6 KXL49364.1 - 4e-73 245.9 0.0 7.9e-73 244.9 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 KXL49364.1 - 1.4e-54 184.8 0.0 4.4e-54 183.2 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 KXL49364.1 - 2.3e-24 85.5 8.1 3.8e-11 43.1 0.1 4.4 1 1 1 3 3 3 3 Tetratricopeptide repeat CLU_N PF15044.6 KXL49364.1 - 2.9e-23 82.0 0.1 7.8e-23 80.6 0.1 1.8 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.6 KXL49364.1 - 2.6e-16 58.9 6.7 9.1e-05 22.2 0.2 5.4 5 1 1 6 6 6 3 Tetratricopeptide repeat DUF727 PF05303.12 KXL49364.1 - 2.3e-05 24.4 0.0 7e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_8 PF13181.6 KXL49364.1 - 0.0071 16.5 6.9 0.33 11.3 0.6 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXL49364.1 - 0.012 15.6 9.4 3.8 7.9 0.4 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Spt20 PF12090.8 KXL49364.1 - 2 8.0 0.0 2 8.0 0.0 3.7 5 1 0 5 5 5 0 Spt20 family AAA_16 PF13191.6 KXL49365.1 - 8.6e-07 29.5 0.2 2.3e-06 28.1 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KXL49365.1 - 0.0071 16.1 0.1 0.016 14.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KXL49365.1 - 0.016 14.8 0.0 0.054 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KXL49365.1 - 0.019 14.5 0.0 0.076 12.5 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 KXL49365.1 - 0.041 13.0 0.0 0.073 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Chitin_synth_1 PF01644.17 KXL49366.1 - 1.2e-77 259.5 0.0 1.8e-77 258.9 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KXL49366.1 - 9e-28 96.0 0.0 1.8e-27 95.0 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KXL49366.1 - 3.4e-25 88.7 1.2 8.7e-22 77.4 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KXL49366.1 - 0.00024 21.1 12.4 0.0003 20.8 9.1 2.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 DUF1361 PF07099.11 KXL49366.1 - 0.0025 17.8 3.2 0.0077 16.2 3.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1361) Glyco_tranf_2_3 PF13641.6 KXL49366.1 - 0.026 14.4 0.0 0.095 12.6 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase like family 2 CitMHS PF03600.16 KXL49366.1 - 0.035 13.3 1.6 0.058 12.6 1.6 1.3 1 0 0 1 1 1 0 Citrate transporter Oxidored_q3 PF00499.20 KXL49366.1 - 2.2 8.0 15.5 0.36 10.5 10.8 2.1 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 SH3_1 PF00018.28 KXL49367.1 - 1.1e-23 82.5 0.0 5.7e-11 41.9 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KXL49367.1 - 1.2e-13 50.6 0.1 1.2e-05 25.1 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 KXL49367.1 - 1.4e-12 47.6 0.1 5.2e-12 45.7 0.0 1.9 2 0 0 2 2 2 1 PX domain SH3_2 PF07653.17 KXL49367.1 - 4.2e-10 39.1 0.0 1.3e-06 27.9 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain Epimerase PF01370.21 KXL49368.1 - 3.9e-16 59.2 0.1 7e-16 58.4 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXL49368.1 - 1.4e-11 44.0 0.0 1.9e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXL49368.1 - 1.8e-11 44.0 0.1 3.8e-11 43.0 0.1 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KXL49368.1 - 1.1e-09 37.8 0.0 9.5e-08 31.5 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 KXL49368.1 - 3.2e-08 33.7 0.2 5.8e-08 32.8 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXL49368.1 - 1.4e-07 31.3 0.0 2.1e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KXL49368.1 - 8.6e-07 28.6 0.2 0.00027 20.5 0.1 2.6 2 1 0 2 2 2 2 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KXL49368.1 - 2.6e-05 23.5 0.0 5.2e-05 22.5 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KXL49368.1 - 0.00064 18.9 0.1 0.044 12.9 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain KR PF08659.10 KXL49368.1 - 0.00088 19.2 0.7 0.0031 17.5 0.6 1.9 1 1 0 1 1 1 1 KR domain HAMP PF00672.25 KXL49370.1 - 1.9e-38 130.6 18.9 1.2e-08 35.2 0.3 7.6 6 2 1 7 7 7 5 HAMP domain HATPase_c PF02518.26 KXL49370.1 - 9.6e-29 100.2 0.8 3.3e-28 98.4 0.3 2.2 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXL49370.1 - 1.2e-26 93.0 1.1 9.5e-26 90.2 0.7 2.6 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KXL49370.1 - 8.9e-16 57.7 0.2 8.9e-16 57.7 0.2 4.2 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain DUF4279 PF14106.6 KXL49370.1 - 8.1e-05 22.8 0.1 17 5.6 0.0 5.4 5 0 0 5 5 5 0 Domain of unknown function (DUF4279) SpoIIID PF12116.8 KXL49370.1 - 0.018 15.1 2.5 29 4.8 0.0 4.9 4 0 0 4 4 4 0 Stage III sporulation protein D DUF3829 PF12889.7 KXL49370.1 - 0.019 14.5 18.6 3.8 6.9 0.1 5.6 4 2 1 6 6 6 0 Protein of unknown function (DUF3829) DUF948 PF06103.11 KXL49370.1 - 0.047 14.0 50.8 2.1 8.6 4.0 10.1 2 2 3 6 6 6 0 Bacterial protein of unknown function (DUF948) CENP-F_leu_zip PF10473.9 KXL49370.1 - 0.074 13.1 31.2 10 6.2 0.1 8.0 7 2 1 8 8 8 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.10 KXL49370.1 - 0.61 10.3 37.6 1.2 9.3 0.2 7.1 6 1 1 7 7 7 0 Fibrinogen alpha/beta chain family ApoLp-III PF07464.11 KXL49370.1 - 0.99 9.5 33.1 0.091 12.9 1.2 6.5 3 2 1 5 5 5 0 Apolipophorin-III precursor (apoLp-III) ImcF-related_N PF14331.6 KXL49370.1 - 3.6 6.9 6.7 8.9 5.6 0.1 4.0 2 1 4 6 6 6 0 ImcF-related N-terminal domain TMPIT PF07851.13 KXL49370.1 - 5.7 6.1 17.0 0.046 13.0 2.5 3.7 3 1 0 4 4 4 0 TMPIT-like protein DUF1759 PF03564.15 KXL49370.1 - 8.8 6.3 16.5 15 5.5 0.0 6.0 6 1 1 7 7 7 0 Protein of unknown function (DUF1759) AcylCoA_dehyd_C PF12186.8 KXL49370.1 - 9.2 6.4 15.1 8.9 6.5 0.5 6.3 6 2 2 8 8 8 0 Acyl-CoA dehydrogenase C terminal bZIP_1 PF00170.21 KXL49371.1 - 0.00028 20.9 2.4 0.0007 19.7 2.4 1.6 1 0 0 1 1 1 1 bZIP transcription factor Mob_synth_C PF06463.13 KXL49371.1 - 0.1 12.5 0.8 0.2 11.6 0.8 1.5 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C Glyco_hydro_31 PF01055.26 KXL49372.1 - 1e-147 492.9 5.2 1.5e-147 492.4 5.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KXL49372.1 - 1.2e-29 102.9 0.0 2.1e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KXL49372.1 - 0.054 13.8 2.4 0.15 12.4 1.4 2.4 2 0 0 2 2 2 0 Galactose mutarotase-like Rotavirus_VP7 PF05868.11 KXL49372.1 - 0.061 12.7 0.3 0.17 11.2 0.3 1.8 1 0 0 1 1 1 0 Rotavirus major outer capsid protein VP7 Pyr_redox_2 PF07992.14 KXL49373.1 - 1.7e-06 27.5 0.0 1.7e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KXL49373.1 - 1.8e-05 24.8 0.0 0.0034 17.5 0.0 3.0 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.6 KXL49373.1 - 0.001 19.2 0.0 0.0084 16.3 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXL49373.1 - 0.0019 17.4 0.0 0.0037 16.5 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXL49373.1 - 0.0023 17.9 0.0 0.26 11.3 0.1 2.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding FMO-like PF00743.19 KXL49373.1 - 0.0045 15.5 0.0 0.0083 14.6 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXL49373.1 - 0.0084 15.4 0.1 0.062 12.6 0.1 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 KXL49373.1 - 0.026 14.7 0.0 0.16 12.1 0.0 2.3 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.21 KXL49373.1 - 0.029 13.7 0.9 0.67 9.3 0.3 2.4 2 0 0 2 2 2 0 ThiF family Lycopene_cycl PF05834.12 KXL49373.1 - 0.046 12.8 0.1 0.42 9.6 0.3 2.3 2 1 0 2 2 2 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 KXL49373.1 - 0.1 12.0 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KXL49373.1 - 0.12 13.0 2.8 34 5.1 1.2 3.4 4 0 0 4 4 4 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.27 KXL49373.1 - 0.13 12.9 0.4 29 5.3 0.0 3.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AA_permease_2 PF13520.6 KXL49374.1 - 4.1e-43 147.8 47.3 5.1e-43 147.5 47.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXL49374.1 - 4.6e-26 91.5 40.9 6.2e-26 91.0 40.9 1.0 1 0 0 1 1 1 1 Amino acid permease Peptidase_S10 PF00450.22 KXL49375.1 - 2.7e-66 224.7 0.7 4.1e-66 224.1 0.7 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Zn_clus PF00172.18 KXL49376.1 - 6.8e-09 35.7 7.2 1.5e-08 34.6 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_N PF02798.20 KXL49377.1 - 4e-13 49.5 0.0 7.5e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXL49377.1 - 9.4e-13 48.4 0.0 1.7e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXL49377.1 - 2.9e-08 33.8 0.0 5.4e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXL49377.1 - 1e-07 32.2 0.0 5.2e-07 29.9 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXL49377.1 - 2.9e-06 27.4 0.1 6.9e-06 26.2 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXL49377.1 - 9.2e-06 25.6 0.0 2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KXL49377.1 - 0.03 14.1 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ACBP PF00887.19 KXL49378.1 - 2.7e-20 72.4 0.5 3.1e-20 72.2 0.5 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein FGAR-AT_linker PF18072.1 KXL49378.1 - 0.12 13.0 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 Formylglycinamide ribonucleotide amidotransferase linker domain PALP PF00291.25 KXL49379.1 - 4.9e-61 206.7 0.0 6.3e-61 206.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 KXL49379.1 - 2e-10 41.0 0.0 1.1e-08 35.4 0.0 2.8 2 0 0 2 2 2 1 CBS domain NAD_binding_2 PF03446.15 KXL49381.1 - 1.8e-30 106.2 0.1 3e-30 105.5 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 KXL49381.1 - 3.2e-12 46.7 0.0 1.1e-11 45.0 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KXL49381.1 - 2.7e-10 40.7 0.1 6.9e-10 39.4 0.0 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.6 KXL49381.1 - 1.3e-08 35.1 0.0 2e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_10 PF13460.6 KXL49381.1 - 2.2e-05 24.4 0.0 3.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXL49381.1 - 0.00028 21.1 0.1 0.00062 20.0 0.1 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain OCD_Mu_crystall PF02423.15 KXL49381.1 - 0.00061 18.8 0.0 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family NAD_binding_3 PF03447.16 KXL49381.1 - 0.0075 16.9 0.0 0.013 16.1 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KXL49381.1 - 0.0082 16.6 0.0 0.029 14.8 0.0 1.8 2 0 0 2 2 2 1 Putative NAD(P)-binding GFO_IDH_MocA PF01408.22 KXL49381.1 - 0.019 15.8 0.0 0.063 14.1 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 KXL49381.1 - 0.022 15.2 0.0 0.04 14.4 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KXL49381.1 - 0.025 14.5 0.4 0.75 9.6 0.1 2.3 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KXL49381.1 - 0.028 14.0 0.0 0.075 12.6 0.0 1.7 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 KXL49381.1 - 0.051 13.8 0.2 0.19 12.0 0.2 1.8 1 1 0 1 1 1 0 TrkA-N domain Transp_cyt_pur PF02133.15 KXL49382.1 - 5.5e-55 186.9 29.3 6.2e-55 186.7 29.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF917 PF06032.12 KXL49383.1 - 3.8e-121 404.2 0.1 6.2e-121 403.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 KXL49383.1 - 6.4e-28 97.7 1.3 3.5e-25 88.7 0.2 3.1 2 1 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 KXL49383.1 - 4.5e-25 88.5 6.5 9.3e-24 84.2 1.7 3.2 2 1 1 3 3 3 2 Hydantoinase/oxoprolinase MutL PF13941.6 KXL49383.1 - 5e-05 22.1 2.0 0.14 10.8 0.2 2.8 3 0 0 3 3 3 2 MutL protein BcrAD_BadFG PF01869.20 KXL49383.1 - 0.00015 21.3 0.2 0.00015 21.3 0.2 3.1 3 1 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.6 KXL49383.1 - 0.53 10.7 7.0 47 4.5 0.1 3.9 2 1 0 2 2 2 0 Cell division protein FtsA Ribosomal_L18A PF01775.17 KXL49384.1 - 1.2e-55 186.7 0.7 1.6e-55 186.4 0.7 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A PCI PF01399.27 KXL49385.1 - 6.9e-10 39.4 0.0 1.8e-09 38.0 0.0 1.8 1 0 0 1 1 1 1 PCI domain BTB PF00651.31 KXL49386.1 - 7.3e-07 29.4 0.0 4.1e-06 27.0 0.0 2.2 3 0 0 3 3 3 1 BTB/POZ domain Skp1_POZ PF03931.15 KXL49386.1 - 0.023 14.9 0.0 0.077 13.2 0.0 1.8 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain Amidohydro_2 PF04909.14 KXL49387.1 - 4.9e-47 161.1 0.1 5.8e-47 160.9 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase ECH_1 PF00378.20 KXL49388.1 - 2.9e-43 148.0 0.0 3.7e-43 147.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXL49388.1 - 2.3e-24 86.5 0.6 1.2e-22 80.9 0.2 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase DivIVA PF05103.13 KXL49389.1 - 0.22 11.6 29.4 0.53 10.4 11.0 3.6 2 1 1 3 3 3 0 DivIVA protein Baculo_F PF12259.8 KXL49389.1 - 0.74 8.3 4.6 1.5 7.3 4.6 1.4 1 0 0 1 1 1 0 Baculovirus F protein CENP-F_leu_zip PF10473.9 KXL49389.1 - 1.8 8.6 37.2 3.1 7.8 4.5 3.3 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AATF-Che1 PF13339.6 KXL49389.1 - 2.5 8.8 12.6 6.2 7.5 0.2 2.8 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Fib_alpha PF08702.10 KXL49389.1 - 3 8.0 22.0 0.031 14.5 6.3 3.4 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF2536 PF10750.9 KXL49389.1 - 6.6 6.7 6.4 1.5 8.7 1.9 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2536) Tropomyosin PF00261.20 KXL49389.1 - 8 5.8 38.3 0.085 12.2 5.3 4.0 2 1 2 4 4 4 0 Tropomyosin Fez1 PF06818.15 KXL49389.1 - 9.4 6.6 31.6 6.7 7.1 13.3 3.1 2 1 1 3 3 3 0 Fez1 TrkH PF02386.16 KXL49390.1 - 3.4e-99 332.6 3.0 1.2e-94 317.6 0.2 2.0 2 0 0 2 2 2 2 Cation transport protein TIP_N PF12457.8 KXL49390.1 - 0.01 16.2 0.1 0.019 15.3 0.1 1.3 1 0 0 1 1 1 0 Tuftelin interacting protein N terminal Senescence PF06911.12 KXL49391.1 - 1.4e-51 175.4 4.3 2e-51 174.9 4.3 1.2 1 0 0 1 1 1 1 Senescence-associated protein zf-RING_2 PF13639.6 KXL49392.1 - 3.5e-09 36.9 2.9 9.6e-09 35.4 2.9 1.8 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KXL49392.1 - 1.1e-07 32.1 1.0 2.2e-07 31.0 1.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KXL49392.1 - 1.6e-06 27.8 2.7 0.00042 20.0 0.4 2.4 2 0 0 2 2 2 2 RING-like zinc finger zf-C3HC4 PF00097.25 KXL49392.1 - 4.1e-06 26.6 1.0 8.3e-06 25.6 1.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXL49392.1 - 6.7e-05 22.7 6.1 0.0001 22.0 1.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXL49392.1 - 9.2e-05 22.3 1.4 0.00017 21.5 1.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KXL49392.1 - 0.00027 20.9 1.0 0.00073 19.5 1.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KXL49392.1 - 0.0027 17.7 3.6 0.007 16.4 3.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KXL49392.1 - 0.034 14.0 5.1 0.074 12.9 5.1 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KXL49392.1 - 0.05 13.5 2.0 0.26 11.2 0.8 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 KXL49392.1 - 0.053 13.8 0.6 0.15 12.4 0.6 1.8 1 0 0 1 1 1 0 RING-like domain TMEM52 PF14979.6 KXL49392.1 - 0.056 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Transmembrane 52 LapA_dom PF06305.11 KXL49392.1 - 0.071 12.9 0.7 0.13 12.1 0.7 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain zf-C3H2C3 PF17122.5 KXL49392.1 - 0.73 9.9 3.1 1.8 8.6 3.1 1.7 1 0 0 1 1 1 0 Zinc-finger Zn_ribbon_17 PF17120.5 KXL49392.1 - 3.3 7.4 6.0 1.1 9.0 0.8 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Ada3 PF10198.9 KXL49393.1 - 8.4e-43 145.7 0.3 8.4e-43 145.7 0.3 1.8 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 IBR PF01485.21 KXL49396.1 - 5.8e-06 26.4 4.7 5.8e-06 26.4 4.7 2.9 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KXL49396.1 - 0.012 15.4 4.2 0.012 15.4 4.2 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXL49396.1 - 0.25 11.2 14.1 0.36 10.7 3.0 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ima1_N PF09779.9 KXL49396.1 - 0.84 10.5 0.0 0.84 10.5 0.0 3.9 3 1 1 4 4 4 0 Ima1 N-terminal domain MMM1 PF10296.9 KXL49397.1 - 0.00023 20.4 0.0 0.00049 19.2 0.0 1.5 2 0 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 DUF5076 PF16826.5 KXL49398.1 - 0.044 13.7 0.0 0.058 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5076) Nas2_N PF18265.1 KXL49399.1 - 3.9e-29 100.4 0.1 8.5e-29 99.3 0.1 1.6 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 KXL49399.1 - 1.4e-10 40.8 0.6 2.7e-10 40.0 0.6 1.5 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 KXL49399.1 - 1.5e-07 31.8 0.0 2.7e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.24 KXL49399.1 - 3.3e-07 30.6 0.1 6.2e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KXL49399.1 - 7e-06 26.3 0.1 1.7e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 PDZ domain Catalase PF00199.19 KXL49400.1 - 3.4e-172 572.9 1.8 4.5e-172 572.5 1.8 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KXL49400.1 - 2.9e-18 65.8 0.0 6.4e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 KXL49400.1 - 2.1e-11 43.7 0.3 1.1e-10 41.3 0.1 2.4 4 0 0 4 4 4 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 KXL49400.1 - 3.1e-09 36.8 0.0 5.4e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family Sel1 PF08238.12 KXL49401.1 - 1.7e-34 117.4 38.7 3.2e-07 30.8 0.5 12.8 12 1 1 13 13 13 9 Sel1 repeat TPR_10 PF13374.6 KXL49401.1 - 1.4 8.9 7.1 2.4 8.2 0.0 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat F-box-like PF12937.7 KXL49402.1 - 5.9e-06 26.1 0.1 1e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXL49402.1 - 0.0014 18.4 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 F-box domain zinc_ribbon_2 PF13240.6 KXL49403.1 - 0.045 13.5 0.3 0.085 12.6 0.3 1.5 1 0 0 1 1 1 0 zinc-ribbon domain LigD_N PF13298.6 KXL49404.1 - 1.2e-32 112.3 0.2 3.7e-32 110.7 0.1 1.9 2 0 0 2 2 2 1 DNA polymerase Ligase (LigD) zf-Tim10_DDP PF02953.15 KXL49405.1 - 2.9e-20 71.7 1.3 3.4e-20 71.4 1.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Tom5 PF10642.9 KXL49405.1 - 0.15 12.1 1.1 0.34 11.0 0.4 2.0 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase FAD_binding_8 PF08022.12 KXL49406.1 - 1.4e-23 83.0 0.0 3.4e-23 81.8 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KXL49406.1 - 2.1e-21 76.7 0.0 4.1e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KXL49406.1 - 3.4e-19 69.2 7.4 3.4e-19 69.2 7.4 2.6 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 KXL49406.1 - 0.069 13.5 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain BIR PF00653.21 KXL49408.1 - 0.02 15.5 0.0 0.066 13.9 0.0 1.8 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain KH_8 PF17903.1 KXL49409.1 - 9.9e-31 105.7 0.0 2.9e-30 104.2 0.0 1.8 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 KXL49409.1 - 0.0045 16.8 0.0 0.013 15.3 0.0 1.8 1 1 0 1 1 1 1 KH domain IBR PF01485.21 KXL49410.1 - 1.8e-06 28.0 31.1 0.0013 19.0 0.5 4.7 3 2 1 4 4 4 2 IBR domain, a half RING-finger domain Aldolase_II PF00596.21 KXL49411.1 - 1.3e-48 165.4 0.1 1.7e-48 165.0 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Kelch_6 PF13964.6 KXL49412.1 - 0.00052 20.2 0.7 0.035 14.4 0.1 3.3 3 0 0 3 3 3 1 Kelch motif DUF1180 PF06679.12 KXL49412.1 - 0.00077 19.9 0.5 0.0032 17.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1180) Kelch_4 PF13418.6 KXL49412.1 - 0.0076 16.2 0.1 0.59 10.2 0.2 2.9 2 0 0 2 2 2 1 Galactose oxidase, central domain UL45 PF05473.12 KXL49412.1 - 0.01 15.5 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like Kelch_2 PF07646.15 KXL49412.1 - 0.04 13.9 1.7 0.41 10.7 0.0 3.4 4 0 0 4 4 4 0 Kelch motif Podoplanin PF05808.11 KXL49412.1 - 0.13 12.4 0.1 0.13 12.4 0.1 2.7 2 1 1 3 3 3 0 Podoplanin TMEM154 PF15102.6 KXL49412.1 - 0.14 12.0 0.8 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 TMEM154 protein family Kelch_1 PF01344.25 KXL49412.1 - 0.19 11.3 2.7 0.21 11.2 0.1 2.6 3 0 0 3 3 3 0 Kelch motif Pyr_redox_2 PF07992.14 KXL49413.1 - 5e-37 127.7 0.3 6.3e-37 127.4 0.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXL49413.1 - 1.2e-12 48.2 0.6 6.2e-12 45.9 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXL49413.1 - 8e-07 28.6 0.1 1.4e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXL49413.1 - 7.1e-05 22.1 0.3 0.00035 19.8 0.0 2.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KXL49413.1 - 0.002 17.4 0.2 2 7.6 0.1 2.5 2 0 0 2 2 2 2 Thi4 family DAO PF01266.24 KXL49413.1 - 0.027 14.1 7.1 0.31 10.6 0.0 3.7 4 0 0 4 4 4 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXL49413.1 - 0.034 13.2 0.3 3.3 6.7 0.0 2.8 2 1 1 3 3 3 0 Lycopene cyclase protein Trp_halogenase PF04820.14 KXL49413.1 - 0.13 11.1 0.4 6.6 5.5 0.2 2.2 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 KXL49413.1 - 0.49 9.0 3.9 1.3 7.6 0.0 2.8 2 1 1 3 3 3 0 HI0933-like protein HIT PF01230.23 KXL49414.1 - 1.5e-15 57.7 0.0 3.1e-15 56.7 0.0 1.5 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KXL49414.1 - 0.0041 17.6 0.3 0.028 14.9 0.3 2.0 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Cyclin_N PF00134.23 KXL49415.1 - 9.3e-46 154.7 0.1 3.3e-44 149.7 0.0 2.6 3 0 0 3 3 3 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXL49415.1 - 2e-35 121.4 0.0 3.8e-35 120.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain Ribosomal_L2_C PF03947.18 KXL49416.1 - 6.5e-51 171.8 1.0 6.5e-51 171.8 1.0 2.1 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KXL49416.1 - 1.4e-24 85.8 2.1 1.8e-24 85.5 0.9 1.8 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Fungal_trans PF04082.18 KXL49418.1 - 1.9e-22 79.6 0.1 3.7e-22 78.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL49418.1 - 1.1e-09 38.2 10.1 2.4e-09 37.1 10.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KXL49419.1 - 1.2e-08 34.9 9.6 1.8e-08 34.3 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.29 KXL49420.1 - 7.5e-49 165.9 0.0 3.1e-48 163.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXL49420.1 - 3.9e-25 88.3 0.1 1.6e-24 86.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL49420.1 - 0.00055 20.0 0.0 0.0016 18.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HMG_box_2 PF09011.10 KXL49421.1 - 3.8e-06 27.4 9.9 9.6e-05 22.9 1.9 3.0 3 1 0 3 3 3 2 HMG-box domain HMG_box PF00505.19 KXL49421.1 - 2.3e-05 24.7 5.6 2.3e-05 24.7 5.6 3.3 3 1 0 3 3 3 2 HMG (high mobility group) box SOBP PF15279.6 KXL49421.1 - 1.9 9.0 6.5 2.3 8.7 6.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein zf-C2H2 PF00096.26 KXL49422.1 - 1.9e-16 59.5 22.6 0.00015 22.0 0.4 5.6 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXL49422.1 - 2.8e-16 59.1 19.4 2.9e-06 27.4 0.1 4.4 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXL49422.1 - 9e-14 51.0 26.0 0.00042 20.9 0.4 5.7 5 1 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXL49422.1 - 6.6e-06 26.3 12.9 0.3 11.4 0.0 5.2 4 1 1 5 5 4 3 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KXL49422.1 - 0.00046 19.7 4.8 0.37 10.4 0.1 3.5 4 0 0 4 4 4 2 Ubiquitin-Binding Zinc Finger XPA_N PF01286.18 KXL49422.1 - 0.0033 17.4 3.2 0.035 14.1 0.2 2.8 3 0 0 3 3 3 1 XPA protein N-terminal zinc_ribbon_9 PF14369.6 KXL49422.1 - 0.0043 17.3 4.5 0.22 11.8 0.1 3.7 3 0 0 3 3 3 1 zinc-ribbon ADK_lid PF05191.14 KXL49422.1 - 0.0078 16.2 1.6 0.0078 16.2 1.6 3.4 3 0 0 3 3 3 1 Adenylate kinase, active site lid FANCA_interact PF15751.5 KXL49422.1 - 0.011 16.2 0.4 0.023 15.2 0.4 1.6 1 0 0 1 1 1 0 FAAP20 FANCA interaction domain zf-Di19 PF05605.12 KXL49422.1 - 0.012 15.9 3.3 0.012 15.9 3.3 3.6 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KXL49422.1 - 0.015 15.3 0.4 0.015 15.3 0.4 4.2 5 0 0 5 5 4 0 C2H2-type zinc finger zf_C2H2_13 PF18508.1 KXL49422.1 - 0.021 14.4 1.1 2.1 8.0 0.1 2.7 2 0 0 2 2 2 0 Zinc finger domain zf-C2H2_11 PF16622.5 KXL49422.1 - 0.036 13.8 10.3 0.82 9.5 0.2 4.5 6 0 0 6 6 5 0 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 KXL49422.1 - 0.04 14.6 9.4 1.2 9.8 0.1 3.5 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats Ogr_Delta PF04606.12 KXL49422.1 - 0.096 12.7 3.7 4.3 7.4 0.0 2.9 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger FOXP-CC PF16159.5 KXL49422.1 - 0.14 12.8 17.7 4.9 7.9 0.6 4.2 2 1 3 5 5 5 0 FOXP coiled-coil domain Zn-ribbon_8 PF09723.10 KXL49422.1 - 0.38 10.9 10.5 6.9 6.9 0.0 3.6 3 1 1 4 4 4 0 Zinc ribbon domain zf-C2H2_9 PF16293.5 KXL49422.1 - 0.72 9.7 3.0 1.5 8.8 0.1 2.8 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) CpXC PF14353.6 KXL49422.1 - 1.8 8.6 5.0 4 7.5 2.5 2.5 1 1 2 3 3 3 0 CpXC protein FAD_binding_3 PF01494.19 KXL49424.1 - 3.3e-18 66.0 0.2 1.7e-17 63.7 0.2 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXL49424.1 - 1.7e-08 34.1 0.0 0.0014 17.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXL49424.1 - 7.6e-07 28.5 0.5 0.019 14.0 0.0 3.1 3 0 0 3 3 3 3 Lycopene cyclase protein HI0933_like PF03486.14 KXL49424.1 - 7.7e-07 28.2 0.2 0.00011 21.1 0.2 2.2 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 KXL49424.1 - 6.3e-06 26.0 1.3 0.00063 19.4 0.3 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXL49424.1 - 2e-05 24.7 0.0 6.9e-05 23.0 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXL49424.1 - 2.3e-05 23.7 0.1 0.00011 21.5 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KXL49424.1 - 0.00014 22.3 0.1 0.0083 16.7 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXL49424.1 - 0.00028 19.9 0.7 0.1 11.4 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase GIDA PF01134.22 KXL49424.1 - 0.00056 19.1 0.2 0.11 11.6 0.3 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 KXL49424.1 - 0.0018 17.7 1.1 0.0041 16.5 0.6 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXL49424.1 - 0.049 12.9 0.0 0.09 12.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXL49424.1 - 0.054 12.8 1.2 0.18 11.1 0.2 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 KXL49424.1 - 0.15 12.1 0.6 8.3 6.4 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding MFS_1 PF07690.16 KXL49425.1 - 2.4e-40 138.5 49.9 4.8e-40 137.6 49.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXL49425.1 - 2.1e-08 33.1 16.0 3.6e-08 32.3 16.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF5337 PF17272.2 KXL49425.1 - 0.12 12.2 3.8 0.14 12.0 1.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5337) TMEM100 PF16311.5 KXL49425.1 - 0.42 10.2 2.5 0.73 9.4 0.0 2.5 2 0 0 2 2 2 0 Transmembrane protein 100 Nup84_Nup100 PF04121.13 KXL49426.1 - 9e-152 506.8 9.0 1.1e-151 506.5 9.0 1.1 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 LpqV PF17301.2 KXL49426.1 - 0.1 12.9 0.1 0.28 11.5 0.1 1.7 1 0 0 1 1 1 0 Putative lipoprotein LpqV DUF3336 PF11815.8 KXL49427.1 - 2.5e-32 111.5 1.4 5.3e-32 110.4 1.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KXL49427.1 - 1.3e-14 54.9 0.1 4.4e-14 53.2 0.1 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase DAGK_cat PF00781.24 KXL49428.1 - 4.7e-26 90.9 0.1 8.5e-26 90.0 0.1 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain MAP65_ASE1 PF03999.12 KXL49429.1 - 0.0006 18.6 2.9 0.0006 18.6 2.9 1.7 2 0 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) Inhibitor_I78 PF11720.8 KXL49430.1 - 2.4e-09 37.1 0.0 2.8e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 KXL49430.1 - 0.0022 18.6 0.0 0.0028 18.3 0.0 1.2 1 0 0 1 1 1 1 Potato inhibitor I family EMC3_TMCO1 PF01956.16 KXL49431.1 - 0.2 11.4 2.1 0.34 10.6 2.1 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DivIC PF04977.15 KXL49431.1 - 0.78 9.5 5.6 0.3 10.9 2.1 2.1 2 0 0 2 2 2 0 Septum formation initiator Abhydrolase_3 PF07859.13 KXL49432.1 - 2.6e-08 34.0 0.0 0.0018 18.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXL49432.1 - 0.00028 21.6 1.4 0.00035 21.3 1.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 KXL49432.1 - 0.0013 18.9 0.0 0.0021 18.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.25 KXL49432.1 - 0.017 15.0 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) DUF915 PF06028.11 KXL49432.1 - 0.021 14.1 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Hydrolase_4 PF12146.8 KXL49432.1 - 0.038 13.2 0.0 0.079 12.2 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXL49432.1 - 0.042 13.5 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.8 KXL49432.1 - 0.19 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) SNF5 PF04855.12 KXL49434.1 - 1.4e-79 267.2 0.0 2e-79 266.8 0.0 1.2 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 KXL49434.1 - 0.00046 19.7 1.6 0.0011 18.6 1.6 1.6 1 0 0 1 1 1 1 GATA zinc finger NUC153 PF08159.12 KXL49434.1 - 0.16 11.8 0.1 0.37 10.7 0.1 1.7 1 0 0 1 1 1 0 NUC153 domain Rubredoxin_2 PF18073.1 KXL49434.1 - 0.26 11.0 5.0 0.21 11.4 1.5 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain Glyco_hydro_61 PF03443.14 KXL49435.1 - 0.08 12.9 0.0 0.14 12.1 0.0 1.7 1 1 0 1 1 1 0 Glycosyl hydrolase family 61 Prefoldin_2 PF01920.20 KXL49438.1 - 2.7e-17 62.7 2.6 2.7e-17 62.7 2.6 1.3 1 1 0 1 1 1 1 Prefoldin subunit T6PP_N PF18572.1 KXL49438.1 - 0.00019 21.2 0.5 0.00027 20.7 0.5 1.2 1 0 0 1 1 1 1 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain AIP3 PF03915.13 KXL49438.1 - 0.0058 15.8 3.0 0.0068 15.6 3.0 1.0 1 0 0 1 1 1 1 Actin interacting protein 3 RasGAP_C PF03836.15 KXL49438.1 - 0.01 16.0 4.7 0.32 11.1 1.2 2.2 2 0 0 2 2 2 0 RasGAP C-terminus GvpG PF05120.12 KXL49438.1 - 0.02 14.9 1.5 0.027 14.5 0.1 1.9 2 1 0 2 2 2 0 Gas vesicle protein G BLOC1_2 PF10046.9 KXL49438.1 - 0.028 14.7 1.1 0.028 14.7 1.1 2.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF812 PF05667.11 KXL49438.1 - 0.028 13.3 4.7 0.047 12.6 4.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF812) CCDC-167 PF15188.6 KXL49438.1 - 0.038 14.3 2.2 0.057 13.8 1.5 1.8 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 BicD PF09730.9 KXL49438.1 - 0.043 12.3 4.8 1.1 7.6 0.7 2.0 2 0 0 2 2 2 0 Microtubule-associated protein Bicaudal-D Spc24 PF08286.11 KXL49438.1 - 0.25 11.6 3.8 1.7 8.9 0.8 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 SlyX PF04102.12 KXL49438.1 - 0.52 11.0 7.0 0.73 10.5 0.6 2.2 2 0 0 2 2 2 0 SlyX DUF4140 PF13600.6 KXL49438.1 - 0.92 10.0 4.7 1.1 9.8 0.4 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Fib_alpha PF08702.10 KXL49438.1 - 1.7 8.9 5.4 0.94 9.7 0.6 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Val_tRNA-synt_C PF10458.9 KXL49438.1 - 2.2 8.6 8.2 0.38 11.1 2.2 2.5 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Ceramidase PF05875.12 KXL49439.1 - 1.2e-106 356.0 7.7 1.3e-106 355.8 7.7 1.0 1 0 0 1 1 1 1 Ceramidase CrgA PF06781.12 KXL49439.1 - 0.057 13.5 1.3 0.36 10.9 0.1 2.5 3 0 0 3 3 3 0 Cell division protein CrgA Fungal_trans PF04082.18 KXL49440.1 - 3.4e-25 88.6 0.6 7.9e-25 87.4 0.4 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL49440.1 - 6.3e-05 23.0 14.3 0.00013 22.0 14.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KXL49441.1 - 1.9e-06 27.9 8.4 1.9e-06 27.9 8.4 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXL49441.1 - 1.2e-05 24.4 0.3 1.8e-05 23.7 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mito_carr PF00153.27 KXL49443.1 - 1.7e-52 175.3 5.0 2e-18 66.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.16 KXL49444.1 - 7.2e-07 28.5 24.4 2e-05 23.7 24.2 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily PsbJ PF01788.17 KXL49444.1 - 0.18 11.7 4.0 0.95 9.4 0.1 2.8 2 0 0 2 2 2 0 PsbJ Iso_dh PF00180.20 KXL49445.1 - 1.7e-103 346.4 0.0 2.3e-103 346.0 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Plasmid_stab_B PF10784.9 KXL49445.1 - 0.042 13.7 0.0 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 Plasmid stability protein Complex1_49kDa PF00346.19 KXL49445.1 - 0.054 12.6 0.0 0.083 12.0 0.0 1.2 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Actin PF00022.19 KXL49446.1 - 2.5e-24 85.7 0.0 8.2e-13 47.7 0.0 3.2 3 0 0 3 3 3 3 Actin MreB_Mbl PF06723.13 KXL49446.1 - 0.00061 18.7 0.0 0.34 9.7 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein PilM_2 PF11104.8 KXL49446.1 - 0.0025 16.9 0.0 2 7.4 0.0 2.2 2 0 0 2 2 2 2 Type IV pilus assembly protein PilM; Nop PF01798.18 KXL49447.1 - 8.7e-81 270.7 0.1 8.7e-81 270.7 0.1 1.7 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KXL49447.1 - 3.3e-22 78.7 1.8 3.3e-22 78.7 1.8 2.2 2 0 0 2 2 2 1 NOP5NT (NUC127) domain YhzD PF14120.6 KXL49447.1 - 0.56 10.4 5.9 1.9 8.6 5.9 2.0 1 0 0 1 1 1 0 YhzD-like protein RNA_pol_Rpb4 PF03874.16 KXL49448.1 - 1.9e-08 34.6 2.1 5.4e-08 33.2 2.1 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb4 DUF2785 PF10978.8 KXL49448.1 - 0.12 12.1 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2785) Glyco_hydro_cc PF11790.8 KXL49450.1 - 2.1e-57 194.4 0.9 2.4e-57 194.3 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core URO-D PF01208.17 KXL49450.1 - 0.063 12.4 0.0 0.086 12.0 0.0 1.1 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) VTC PF09359.10 KXL49451.1 - 1.1e-101 339.8 0.0 1.1e-101 339.8 0.0 1.7 2 0 0 2 2 2 1 VTC domain SPX PF03105.19 KXL49451.1 - 2.5e-15 57.3 23.1 2.2e-06 27.9 0.1 4.3 3 1 1 4 4 4 3 SPX domain DUF202 PF02656.15 KXL49451.1 - 0.033 14.6 0.0 0.062 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Ribosomal_60s PF00428.19 KXL49451.1 - 0.27 11.9 8.9 1.6 9.4 2.8 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein TPT PF03151.16 KXL49452.1 - 2.1e-09 37.2 6.4 2.6e-09 36.9 6.4 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KXL49452.1 - 0.0018 17.5 5.6 0.0023 17.2 5.6 1.3 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KXL49452.1 - 0.0066 16.6 12.3 0.0066 16.6 12.3 1.6 2 0 0 2 2 2 1 EamA-like transporter family DUF2070 PF09843.9 KXL49452.1 - 0.55 8.5 10.7 0.72 8.1 10.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) F-box-like PF12937.7 KXL49453.1 - 5e-05 23.1 0.4 0.00011 22.0 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXL49453.1 - 6.6e-05 22.7 0.1 0.00013 21.8 0.1 1.5 1 0 0 1 1 1 1 F-box domain SAE2 PF08573.10 KXL49454.1 - 5e-26 92.0 0.3 5e-26 92.0 0.3 3.2 3 0 0 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus DUF4446 PF14584.6 KXL49454.1 - 0.1 12.6 1.3 0.29 11.1 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Prominin PF05478.11 KXL49454.1 - 3 5.7 4.5 4.2 5.2 4.5 1.1 1 0 0 1 1 1 0 Prominin HLH PF00010.26 KXL49455.1 - 8.7e-13 48.0 1.9 4.6e-12 45.7 0.0 2.4 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain NEMO PF11577.8 KXL49455.1 - 0.018 15.0 2.1 0.023 14.7 0.4 2.0 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO YabA PF06156.13 KXL49455.1 - 0.18 12.5 1.8 0.93 10.2 0.0 2.4 3 0 0 3 3 3 0 Initiation control protein YabA ZapB PF06005.12 KXL49455.1 - 0.27 11.7 0.3 0.27 11.7 0.3 2.7 3 0 0 3 3 3 0 Cell division protein ZapB bZIP_2 PF07716.15 KXL49455.1 - 2.4 8.3 8.2 2 8.6 1.5 2.5 2 0 0 2 2 2 0 Basic region leucine zipper Inhibitor_I9 PF05922.16 KXL49456.1 - 0.08 13.6 0.0 0.095 13.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase inhibitor I9 DUF2452 PF10504.9 KXL49456.1 - 0.19 11.2 0.1 0.2 11.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) CFIA_Pcf11 PF11526.8 KXL49457.1 - 3e-05 24.4 0.2 9.5e-05 22.8 0.2 1.9 1 0 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 CTD_bind PF04818.13 KXL49457.1 - 0.00012 22.8 0.0 0.0026 18.6 0.0 3.2 4 0 0 4 4 4 1 RNA polymerase II-binding domain. VHS PF00790.19 KXL49457.1 - 0.0011 18.8 0.0 0.0035 17.2 0.0 1.8 1 0 0 1 1 1 1 VHS domain zf_UBZ PF18439.1 KXL49457.1 - 0.021 14.4 4.9 0.46 10.1 1.5 3.1 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 KXL49457.1 - 0.79 9.7 3.5 0.31 11.0 0.2 2.1 2 0 0 2 2 2 0 zinc-finger of a C2HC-type GrpE PF01025.19 KXL49458.1 - 0.026 14.2 10.0 0.022 14.4 8.0 1.8 2 0 0 2 2 2 0 GrpE DUF3584 PF12128.8 KXL49458.1 - 0.028 11.9 10.1 0.041 11.4 10.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) z-alpha PF02295.17 KXL49458.1 - 0.25 11.4 1.0 2.2 8.4 0.0 2.3 2 0 0 2 2 2 0 Adenosine deaminase z-alpha domain FlxA PF14282.6 KXL49458.1 - 0.28 11.2 0.0 0.28 11.2 0.0 3.5 2 1 0 2 2 2 0 FlxA-like protein ExsD PF16806.5 KXL49458.1 - 0.35 10.8 7.1 0.75 9.7 7.1 1.5 1 0 0 1 1 1 0 Antiactivator protein ExsD GIDA_assoc PF13932.6 KXL49458.1 - 0.79 9.9 5.7 1.5 9.0 5.7 1.4 1 0 0 1 1 1 0 GidA associated domain KIP1 PF07765.12 KXL49458.1 - 0.82 9.8 3.7 2.6 8.3 3.7 1.9 1 0 0 1 1 1 0 KIP1-like protein Fungal_trans PF04082.18 KXL49459.1 - 9.9e-06 24.8 0.1 1.6e-05 24.1 0.1 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain EthD PF07110.11 KXL49460.1 - 0.16 13.1 0.0 0.21 12.8 0.0 1.1 1 0 0 1 1 1 0 EthD domain DUF382 PF04037.13 KXL49461.1 - 3.3e-58 195.3 0.7 3.3e-58 195.3 0.7 3.2 5 0 0 5 5 5 1 Domain of unknown function (DUF382) PSP PF04046.16 KXL49461.1 - 1.1e-21 76.4 6.2 2.5e-21 75.2 6.2 1.7 1 0 0 1 1 1 1 PSP ANAPC15 PF15243.6 KXL49462.1 - 0.078 13.4 1.1 0.12 12.8 1.0 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 15 ACCA PF03255.14 KXL49462.1 - 0.19 11.6 1.8 0.26 11.1 1.8 1.2 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Trimer_CC PF08954.11 KXL49462.1 - 5.4 6.7 8.6 0.37 10.4 0.7 2.5 3 0 0 3 3 3 0 Trimerisation motif Alpha-amylase_C PF02806.18 KXL49463.1 - 1.1e-26 93.1 0.0 2.2e-26 92.2 0.0 1.5 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 KXL49463.1 - 7.7e-17 61.4 0.0 1.7e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KXL49463.1 - 7.4e-14 52.0 0.6 1.5e-10 41.2 0.2 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain AAA_2 PF07724.14 KXL49464.1 - 5.6e-39 134.0 0.0 3e-38 131.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KXL49464.1 - 1.3e-14 54.7 0.0 2.6e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KXL49464.1 - 4.9e-10 39.3 0.0 1.3e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KXL49464.1 - 4.4e-07 30.0 0.0 1.2e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KXL49464.1 - 0.00021 20.8 0.2 0.016 14.6 0.0 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI MCM PF00493.23 KXL49464.1 - 0.0011 18.1 0.0 0.0024 17.0 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain Sigma54_activat PF00158.26 KXL49464.1 - 0.0017 18.1 0.0 0.12 12.1 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_24 PF13479.6 KXL49464.1 - 0.002 17.9 0.0 0.0031 17.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXL49464.1 - 0.0023 18.3 0.8 0.0071 16.7 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXL49464.1 - 0.0023 18.2 0.2 0.023 14.9 0.2 2.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KXL49464.1 - 0.0059 16.4 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 KXL49464.1 - 0.0086 15.8 0.1 0.055 13.2 0.0 2.3 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 KXL49464.1 - 0.041 13.8 0.1 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KXL49464.1 - 0.053 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KXL49464.1 - 0.061 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 KXL49464.1 - 0.09 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KXL49464.1 - 0.18 11.8 0.0 0.42 10.6 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KXL49464.1 - 0.24 11.9 0.0 0.24 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF775 PF05603.12 KXL49466.1 - 0.26 10.8 3.3 0.4 10.2 3.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF775) Mannosyl_trans3 PF11051.8 KXL49467.1 - 7.6e-58 196.0 0.0 4e-57 193.7 0.0 2.0 1 1 0 1 1 1 1 Mannosyltransferase putative Fringe PF02434.16 KXL49468.1 - 1e-09 38.2 0.4 1.5e-08 34.4 0.2 2.3 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.6 KXL49468.1 - 0.018 15.0 0.6 0.018 15.0 0.6 2.1 2 0 0 2 2 2 0 PAN domain DUF4132 PF13569.6 KXL49468.1 - 0.088 12.6 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4132) EamA PF00892.20 KXL49469.1 - 6.1e-06 26.5 9.4 6.1e-06 26.5 9.4 2.2 2 0 0 2 2 2 1 EamA-like transporter family TPT PF03151.16 KXL49469.1 - 0.003 17.0 22.8 0.029 13.7 22.8 2.7 1 1 0 1 1 1 1 Triose-phosphate Transporter family Methyltransf_21 PF05050.12 KXL49470.1 - 3.4e-08 33.7 0.0 4.3e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase FkbM domain MFS_5 PF05631.14 KXL49471.1 - 1.3e-67 228.2 4.7 1.9e-67 227.7 4.7 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 KXL49471.1 - 1.6e-25 89.8 17.8 2.7e-25 89.0 17.8 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KXL49471.1 - 3.2e-08 32.9 0.0 0.00091 18.2 0.4 2.7 2 1 0 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 KXL49471.1 - 1.2e-06 27.7 19.2 4.3e-06 25.8 9.5 3.1 1 1 1 2 2 2 2 Sugar (and other) transporter DUF5401 PF17380.2 KXL49472.1 - 0.05 11.7 0.2 0.056 11.5 0.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) WTF PF03303.13 KXL49472.1 - 0.39 10.4 1.8 0.49 10.1 1.4 1.3 1 1 0 1 1 1 0 WTF protein HTH_28 PF13518.6 KXL49474.1 - 5.5e-05 23.2 0.0 8.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 KXL49474.1 - 0.0012 18.8 0.0 0.0018 18.3 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 KXL49474.1 - 0.0023 17.7 0.0 0.0034 17.1 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_30 PF13556.6 KXL49474.1 - 0.0041 16.9 0.1 0.0084 15.9 0.1 1.6 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain HRDC PF00570.23 KXL49474.1 - 0.0061 16.5 0.0 0.0093 15.9 0.0 1.3 1 0 0 1 1 1 1 HRDC domain HTH_Tnp_ISL3 PF13542.6 KXL49474.1 - 0.0092 15.4 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 MarR PF01047.22 KXL49474.1 - 0.019 14.9 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 MarR family MarR_2 PF12802.7 KXL49474.1 - 0.037 13.9 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 MarR family AnmK PF03702.14 KXL49474.1 - 0.087 11.9 0.0 0.097 11.8 0.0 1.0 1 0 0 1 1 1 0 Anhydro-N-acetylmuramic acid kinase HTH_psq PF05225.16 KXL49474.1 - 0.098 12.4 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 helix-turn-helix, Psq domain ICMT PF04140.14 KXL49475.1 - 3.3e-08 33.8 0.0 6e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KXL49475.1 - 2.9e-07 30.9 0.1 5.3e-07 30.0 0.1 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase TPR_9 PF13371.6 KXL49475.1 - 0.062 13.5 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat G-patch PF01585.23 KXL49476.1 - 0.021 14.7 1.5 0.025 14.5 0.3 1.7 2 0 0 2 2 2 0 G-patch domain Thg1 PF04446.12 KXL49477.1 - 1.8e-49 166.9 0.0 2.7e-49 166.3 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 KXL49477.1 - 2.3e-49 166.6 0.0 3.2e-49 166.2 0.0 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain DUF3365 PF11845.8 KXL49478.1 - 0.025 14.9 0.0 0.028 14.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) HET PF06985.11 KXL49479.1 - 1.1e-33 116.6 0.1 2.2e-33 115.6 0.1 1.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Syja_N PF02383.18 KXL49483.1 - 8.7e-93 311.1 0.1 8.7e-93 311.1 0.1 1.4 2 0 0 2 2 2 1 SacI homology domain Ras PF00071.22 KXL49484.1 - 1.5e-59 200.2 0.3 1.9e-59 199.9 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXL49484.1 - 6.5e-37 126.4 0.2 2.5e-36 124.5 0.1 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXL49484.1 - 3.5e-15 55.9 0.0 4.4e-15 55.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KXL49484.1 - 1.5e-06 27.7 0.0 1.9e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KXL49484.1 - 2e-06 27.5 0.0 3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KXL49484.1 - 2.4e-06 27.6 0.0 4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXL49484.1 - 5.2e-06 26.5 1.1 0.035 14.0 0.2 2.4 1 1 2 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 KXL49484.1 - 0.012 16.0 0.1 0.02 15.3 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KXL49484.1 - 0.091 13.0 0.0 2.6 8.3 0.0 2.3 1 1 1 2 2 2 0 AAA domain Innate_immun PF12782.7 KXL49484.1 - 5.7 6.4 8.5 5.6 6.4 3.5 2.1 2 0 0 2 2 2 0 Invertebrate innate immunity transcript family Methyltransf_23 PF13489.6 KXL49485.1 - 8.3e-14 51.8 0.0 1.3e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL49485.1 - 1.1e-11 45.2 0.0 4.9e-11 43.1 0.0 2.1 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL49485.1 - 1.2e-10 41.4 0.0 3.2e-09 36.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL49485.1 - 4.2e-10 40.2 0.0 2.4e-09 37.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL49485.1 - 2.3e-09 37.9 0.0 1e-08 35.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXL49485.1 - 1.6e-08 34.2 0.0 5.2e-08 32.5 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KXL49485.1 - 9.2e-05 22.3 0.1 0.00037 20.3 0.1 1.8 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 KXL49485.1 - 0.0021 17.8 0.0 0.0036 17.0 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KXL49485.1 - 0.013 15.1 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 KXL49485.1 - 0.015 14.7 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 KXL49485.1 - 0.094 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DREV PF05219.12 KXL49485.1 - 0.096 11.8 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_32 PF13679.6 KXL49485.1 - 0.098 12.6 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CorA PF01544.18 KXL49486.1 - 2.4e-08 33.6 0.0 4.7e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF350 PF03994.14 KXL49486.1 - 0.11 12.6 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF350) G-gamma PF00631.22 KXL49487.1 - 6.1e-23 80.6 0.0 7.3e-23 80.4 0.0 1.1 1 0 0 1 1 1 1 GGL domain PCI PF01399.27 KXL49490.1 - 8e-09 36.0 0.7 2.7e-08 34.2 0.1 2.3 2 0 0 2 2 2 1 PCI domain MRP-L20 PF12824.7 KXL49491.1 - 1.1e-53 181.8 9.2 1.3e-53 181.6 9.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.11 KXL49491.1 - 0.00016 21.8 0.2 0.00033 20.8 0.1 1.5 1 1 0 1 1 1 1 Neugrin HTH_32 PF13565.6 KXL49491.1 - 1.1 10.0 8.1 0.23 12.1 1.2 2.8 2 1 1 3 3 3 0 Homeodomain-like domain Peptidase_S10 PF00450.22 KXL49492.1 - 9.2e-83 279.0 0.1 1.2e-82 278.6 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Flavin_Reduct PF01613.18 KXL49493.1 - 4.2e-24 85.4 0.6 7.9e-24 84.5 0.6 1.4 1 0 0 1 1 1 1 Flavin reductase like domain KH_1 PF00013.29 KXL49493.1 - 0.055 13.3 0.0 7 6.6 0.0 3.2 3 0 0 3 3 3 0 KH domain ECH_1 PF00378.20 KXL49494.1 - 1.9e-16 60.1 0.0 3.2e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Formyl_trans_C PF02911.18 KXL49494.1 - 2.9e-05 24.2 0.0 6.3e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Formyl_trans_N PF00551.19 KXL49494.1 - 0.00014 21.7 0.0 0.028 14.2 0.0 2.4 2 0 0 2 2 2 2 Formyl transferase PDCD2_C PF04194.13 KXL49495.1 - 6.5e-44 150.1 0.0 1.6e-42 145.6 0.0 2.2 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain FAM60A PF15396.6 KXL49497.1 - 0.74 9.8 5.8 1.4 8.9 5.8 1.4 1 0 0 1 1 1 0 Protein Family FAM60A UT PF03253.14 KXL49498.1 - 0.075 12.1 8.0 0.11 11.6 8.0 1.1 1 0 0 1 1 1 0 Urea transporter Peptidase_U4 PF03419.13 KXL49498.1 - 0.82 8.9 4.8 1.1 8.5 4.8 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA DnaJ_C PF01556.18 KXL49499.1 - 2.3e-40 138.1 0.2 3.1e-40 137.7 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KXL49499.1 - 1.7e-23 82.5 1.0 2.9e-23 81.7 1.0 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KXL49499.1 - 7.7e-17 61.4 18.0 1.4e-16 60.6 18.0 1.5 1 0 0 1 1 1 1 DnaJ central domain RPT PF13446.6 KXL49499.1 - 0.17 11.8 0.0 0.4 10.6 0.0 1.6 1 0 0 1 1 1 0 A repeated domain in UCH-protein HypA PF01155.19 KXL49499.1 - 0.18 11.8 10.7 1.8 8.6 0.9 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 KXL49499.1 - 0.33 10.9 19.4 1.7 8.7 3.7 2.6 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein zinc-ribbons_6 PF07191.12 KXL49499.1 - 3.7 7.6 9.5 11 6.1 2.8 2.3 1 1 1 2 2 2 0 zinc-ribbons DUF2614 PF11023.8 KXL49499.1 - 9.3 6.4 7.1 17 5.5 0.6 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain FR47 PF08445.10 KXL49501.1 - 8.4e-06 25.7 0.0 2.2e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 KXL49501.1 - 0.0066 16.7 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXL49501.1 - 0.009 16.4 0.0 0.047 14.1 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXL49501.1 - 0.13 12.2 0.0 0.35 10.8 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Ribosomal_L10 PF00466.20 KXL49502.1 - 2.2e-22 79.1 0.2 5.8e-22 77.7 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 KXL49502.1 - 4.2e-22 77.9 0.2 1e-21 76.7 0.0 1.7 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 KXL49502.1 - 3.6e-20 72.4 6.1 3.6e-20 72.4 6.1 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein DUF108 PF01958.18 KXL49502.1 - 0.027 14.9 0.7 0.083 13.3 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF108 WD40 PF00400.32 KXL49503.1 - 0.0029 18.4 1.5 1.9 9.5 0.4 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat CPSF_A PF03178.15 KXL49503.1 - 0.016 14.5 0.0 0.064 12.6 0.0 1.9 2 0 0 2 2 2 0 CPSF A subunit region ANAPC4_WD40 PF12894.7 KXL49503.1 - 0.051 13.9 0.0 24 5.3 0.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain FAD_binding_3 PF01494.19 KXL49504.1 - 2.5e-20 73.1 0.0 2.2e-19 69.9 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXL49504.1 - 1.8e-09 37.7 2.8 0.00059 19.5 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXL49504.1 - 1.1e-08 34.6 0.0 0.00053 19.3 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXL49504.1 - 2.1e-07 31.0 0.3 1.6e-06 28.2 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXL49504.1 - 4.8e-07 29.2 0.0 8e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KXL49504.1 - 1.4e-06 27.7 0.1 2.2e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KXL49504.1 - 0.00014 22.3 0.2 0.014 16.0 0.4 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXL49504.1 - 0.00026 19.8 0.4 0.0015 17.3 0.4 1.9 1 1 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 KXL49504.1 - 0.0043 16.4 0.1 0.26 10.5 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 KXL49504.1 - 0.016 14.6 0.5 0.03 13.7 0.4 1.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 KXL49504.1 - 0.02 14.0 0.0 0.031 13.4 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KXL49504.1 - 0.055 12.7 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Rossmann-like PF10727.9 KXL49504.1 - 0.067 13.0 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Rossmann-like domain ApbA PF02558.16 KXL49504.1 - 0.18 11.5 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Fungal_trans PF04082.18 KXL49505.1 - 2e-19 69.7 0.5 4.1e-19 68.6 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL49505.1 - 0.0077 16.3 10.8 0.017 15.2 10.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.22 KXL49506.1 - 5.7e-108 361.4 2.5 5.8e-105 351.5 0.4 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family SPW PF03779.14 KXL49506.1 - 0.011 15.3 0.9 0.032 13.8 0.9 1.8 1 0 0 1 1 1 0 SPW repeat Folliculin_C PF16692.5 KXL49506.1 - 0.23 11.1 0.1 0.48 10.1 0.1 1.4 1 0 0 1 1 1 0 Folliculin C-terminal domain Pkinase PF00069.25 KXL49507.1 - 2e-41 142.1 0.0 2.2e-41 141.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL49507.1 - 4.6e-28 98.2 0.0 5.1e-28 98.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXL49507.1 - 0.017 13.9 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KXL49507.1 - 0.048 13.3 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.11 KXL49507.1 - 0.18 10.7 0.0 0.23 10.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase NUDIX_2 PF13869.6 KXL49508.1 - 3.6e-79 264.7 0.0 4.6e-79 264.4 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase GATase_6 PF13522.6 KXL49509.1 - 3.3e-08 33.8 0.0 5.7e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KXL49509.1 - 9.2e-07 28.0 0.1 6.8e-06 25.2 0.1 2.3 1 1 0 1 1 1 1 Glutamine amidotransferases class-II Glycogen_syn PF05693.13 KXL49510.1 - 0 1134.0 0.0 0 1133.7 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 KXL49510.1 - 7.5e-05 22.3 0.0 0.039 13.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KXL49510.1 - 0.00098 19.6 0.0 0.0021 18.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 KXL49510.1 - 0.0014 19.0 0.0 1.1 9.7 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXL49510.1 - 0.0015 18.5 0.2 0.0028 17.7 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.11 KXL49510.1 - 0.021 14.5 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain ETF PF01012.21 KXL49511.1 - 2e-45 154.9 1.1 3.5e-45 154.1 1.1 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KXL49511.1 - 8.8e-34 115.4 0.1 1.7e-33 114.5 0.1 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Eaf7 PF07904.13 KXL49512.1 - 1.6e-25 89.5 0.0 1.6e-25 89.5 0.0 2.0 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 CCDC53 PF10152.9 KXL49512.1 - 0.92 9.9 7.5 0.8 10.1 2.7 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex RNA_pol_Rpc4 PF05132.14 KXL49512.1 - 3.2 8.2 8.3 0.95 9.9 2.8 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 BSP_II PF05432.11 KXL49512.1 - 3.4 7.3 17.8 0.19 11.4 7.7 2.1 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) PKD_channel PF08016.12 KXL49513.1 - 5.6e-06 25.3 12.4 0.0099 14.6 0.5 2.3 1 1 1 2 2 2 2 Polycystin cation channel Ion_trans PF00520.31 KXL49513.1 - 1.8e-05 24.1 24.5 1.8e-05 24.1 24.5 2.8 2 1 0 2 2 2 1 Ion transport protein TAFA PF12020.8 KXL49513.1 - 0.083 13.4 0.1 0.34 11.4 0.1 2.0 1 1 1 2 2 2 0 TAFA family Cupin_2 PF07883.11 KXL49514.1 - 1.3e-06 28.0 0.4 2.4e-06 27.2 0.4 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KXL49514.1 - 8.9e-06 25.4 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Cupin ARD PF03079.14 KXL49514.1 - 0.0076 16.4 0.0 0.0099 16.1 0.0 1.2 1 0 0 1 1 1 1 ARD/ARD' family Cupin_6 PF12852.7 KXL49514.1 - 0.059 13.1 0.0 0.071 12.8 0.0 1.1 1 0 0 1 1 1 0 Cupin HTH_psq PF05225.16 KXL49515.1 - 5.3e-09 35.7 0.2 7e-09 35.3 0.2 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_50 PF18024.1 KXL49515.1 - 0.0012 18.4 0.1 0.0019 17.8 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain TGase_elicitor PF16683.5 KXL49515.1 - 0.14 10.9 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Transglutaminase elicitor DnaJ PF00226.31 KXL49516.1 - 1e-15 57.6 1.5 3.5e-15 55.9 1.5 2.0 1 0 0 1 1 1 1 DnaJ domain Bac_rhamnosid6H PF17389.2 KXL49517.1 - 4e-15 55.9 0.7 1.7e-14 53.9 0.6 1.8 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 KXL49517.1 - 2.6e-05 23.9 0.0 5.5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Flavin_Reduct PF01613.18 KXL49518.1 - 2e-14 53.9 0.0 2.8e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain peroxidase PF00141.23 KXL49519.1 - 3.5e-17 62.9 0.0 4.4e-17 62.5 0.0 1.0 1 0 0 1 1 1 1 Peroxidase Pns11_12 PF17464.2 KXL49520.1 - 1.1 9.0 7.5 1.2 8.8 7.5 1.0 1 0 0 1 1 1 0 Non-structural protein 11 and 12 Peptidase_M48 PF01435.18 KXL49521.1 - 9.7e-38 129.9 0.0 1.8e-37 129.1 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M48 Amidohydro_1 PF01979.20 KXL49522.1 - 2.8e-25 89.4 0.1 7.3e-25 88.0 0.1 1.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXL49522.1 - 1.5e-10 41.2 3.3 6.6e-06 25.9 0.1 2.4 2 1 0 2 2 2 2 Amidohydrolase family adh_short PF00106.25 KXL49523.1 - 3.7e-46 157.1 0.1 4.4e-46 156.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL49523.1 - 1.7e-44 152.1 0.0 2.2e-44 151.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL49523.1 - 2.2e-08 34.2 1.3 3e-07 30.5 1.3 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL49523.1 - 0.001 18.6 0.1 0.0035 16.8 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXL49523.1 - 0.045 12.8 0.0 0.058 12.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXL49523.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KXL49523.1 - 0.13 11.4 0.3 1.9 7.6 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein AdoHcyase_NAD PF00670.21 KXL49523.1 - 0.14 12.2 0.3 0.26 11.3 0.3 1.5 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Sugar_tr PF00083.24 KXL49524.1 - 2.8e-109 366.0 14.6 3.4e-109 365.7 14.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL49524.1 - 1.8e-28 99.5 25.1 2.1e-28 99.3 16.4 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXL49524.1 - 0.0097 14.8 3.3 0.13 11.1 0.0 3.2 2 1 2 4 4 4 1 MFS_1 like family DUF962 PF06127.11 KXL49524.1 - 0.21 11.7 2.6 0.39 10.8 0.1 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF962) DUF2207 PF09972.9 KXL49524.1 - 5.2 5.7 4.9 1.5 7.5 0.7 2.2 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) SKIP_SNW PF02731.15 KXL49526.1 - 1.1e-69 233.2 6.2 1.1e-69 233.2 6.2 2.2 2 0 0 2 2 2 1 SKIP/SNW domain UPF0029 PF01205.19 KXL49527.1 - 1.4e-35 121.8 0.0 2e-35 121.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 KXL49527.1 - 7.1e-05 23.1 0.0 0.00021 21.5 0.0 1.8 1 1 0 1 1 1 1 RWD domain UQ_con PF00179.26 KXL49527.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme Rsm22 PF09243.10 KXL49528.1 - 5.4e-27 94.8 0.0 4e-18 65.7 0.0 2.9 2 1 0 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 DEAD PF00270.29 KXL49529.1 - 3.4e-42 144.2 0.0 6.5e-42 143.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXL49529.1 - 3.8e-26 91.6 0.0 1.2e-25 90.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UTP25 PF06862.12 KXL49529.1 - 0.0033 16.3 0.0 0.069 11.9 0.0 2.6 3 0 0 3 3 3 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 SNF2_N PF00176.23 KXL49529.1 - 0.01 14.6 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain ResIII PF04851.15 KXL49529.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF3433 PF11915.8 KXL49530.1 - 1.1e-32 112.3 24.8 9.9e-24 83.6 2.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Pkinase PF00069.25 KXL49532.1 - 2.1e-65 220.7 0.1 5.9e-65 219.2 0.1 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL49532.1 - 3.6e-28 98.6 0.1 1.4e-27 96.6 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXL49532.1 - 7.2e-08 32.1 0.0 2e-07 30.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KXL49532.1 - 5.1e-06 25.5 0.0 8.5e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXL49532.1 - 2.8e-05 23.6 0.0 6.1e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KXL49532.1 - 0.0026 17.3 0.0 0.0098 15.4 0.0 1.8 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL APH PF01636.23 KXL49532.1 - 0.022 14.7 0.1 0.092 12.6 0.0 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family XPA_C PF05181.12 KXL49534.1 - 5.4e-26 90.3 4.0 1.2e-25 89.2 4.0 1.6 1 0 0 1 1 1 1 XPA protein C-terminus zf-AD PF07776.15 KXL49534.1 - 0.012 15.8 1.5 0.042 14.1 0.6 2.3 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) AA_kinase PF00696.28 KXL49535.1 - 3e-39 135.1 0.7 5.3e-39 134.2 0.7 1.4 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 KXL49535.1 - 2.1e-11 43.4 0.6 1.1e-06 28.3 0.1 2.7 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 KXL49535.1 - 7.8e-10 38.4 0.4 5.5e-07 29.3 0.0 2.6 2 0 0 2 2 2 2 ACT domain RIX1 PF08167.12 KXL49536.1 - 2.6e-51 174.0 8.5 2.6e-51 174.0 8.5 2.7 3 1 0 3 3 3 1 rRNA processing/ribosome biogenesis TPR_14 PF13428.6 KXL49537.1 - 1.1e-14 53.9 2.4 2.8 9.0 0.0 9.4 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXL49537.1 - 2.9e-10 40.5 3.3 0.059 13.9 0.1 7.5 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXL49537.1 - 1.1e-07 31.5 1.4 0.65 10.4 0.4 6.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXL49537.1 - 1.2e-07 31.2 0.5 0.64 10.3 0.3 6.6 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXL49537.1 - 2.7e-07 30.1 1.0 0.89 9.5 0.1 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXL49537.1 - 0.0052 17.1 1.2 0.4 11.2 0.3 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KXL49537.1 - 0.16 12.7 3.1 48 4.9 0.6 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat P5-ATPase PF12409.8 KXL49538.1 - 1.1e-38 132.2 0.4 2.5e-38 131.0 0.4 1.7 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 KXL49538.1 - 7e-31 107.1 0.0 4.7e-30 104.5 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KXL49538.1 - 4.5e-15 56.5 0.5 1.5e-07 31.9 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXL49538.1 - 0.00047 19.8 0.0 0.0014 18.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXL49538.1 - 0.0023 17.7 0.2 1.2 8.8 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXL49538.1 - 0.019 15.1 0.0 0.046 13.8 0.0 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) CMAS PF02353.20 KXL49539.1 - 7.7e-36 123.8 1.6 1.2e-35 123.2 1.6 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 KXL49539.1 - 9.9e-17 61.1 0.0 1.5e-16 60.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL49539.1 - 4.1e-13 49.8 0.0 8.6e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL49539.1 - 5e-13 49.5 0.0 8.7e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXL49539.1 - 1e-12 48.2 0.0 1.4e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL49539.1 - 1.4e-10 41.8 0.0 2.7e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXL49539.1 - 8.7e-07 28.6 0.0 2.2e-06 27.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KXL49539.1 - 2.2e-05 24.0 0.0 5.4e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase TehB PF03848.14 KXL49539.1 - 0.00023 20.7 0.0 0.00036 20.0 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltr_RsmB-F PF01189.17 KXL49539.1 - 0.00024 20.8 0.0 0.00053 19.7 0.0 1.5 2 0 0 2 2 1 1 16S rRNA methyltransferase RsmB/F Ubie_methyltran PF01209.18 KXL49539.1 - 0.001 18.5 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KXL49539.1 - 0.0021 18.2 0.0 0.011 15.8 0.0 1.9 1 1 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 KXL49539.1 - 0.0049 16.7 0.0 0.0086 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.12 KXL49539.1 - 0.0062 16.3 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) RrnaAD PF00398.20 KXL49539.1 - 0.0064 15.6 0.0 0.0097 15.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 KXL49539.1 - 0.0084 16.1 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF1122 PF06557.11 KXL49539.1 - 0.0095 15.4 0.0 0.028 13.9 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1122) FTO_CTD PF12934.7 KXL49539.1 - 0.027 14.2 1.4 0.062 13.1 1.4 1.5 1 0 0 1 1 1 0 FTO C-terminal domain MyTH4 PF00784.17 KXL49539.1 - 0.03 14.8 0.1 0.088 13.3 0.1 1.8 1 0 0 1 1 1 0 MyTH4 domain GidB PF02527.15 KXL49539.1 - 0.031 13.6 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G tRNA_U5-meth_tr PF05958.11 KXL49539.1 - 0.034 13.2 0.0 0.049 12.6 0.0 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_2 PF00891.18 KXL49539.1 - 0.044 13.1 0.0 0.12 11.7 0.0 1.7 1 1 0 1 1 1 0 O-methyltransferase domain TRM13 PF05206.14 KXL49539.1 - 0.096 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase TRM13 MetW PF07021.12 KXL49539.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW NADH_B2 PF14813.6 KXL49540.1 - 0.0031 17.3 0.1 0.0036 17.1 0.1 1.2 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 Pkinase PF00069.25 KXL49541.1 - 1.8e-65 221.0 0.0 2.3e-65 220.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL49541.1 - 1.4e-27 96.6 0.0 2.1e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXL49541.1 - 0.02 13.7 0.0 0.028 13.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KXL49541.1 - 0.037 13.0 0.0 0.052 12.5 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KXL49541.1 - 0.13 11.5 0.0 0.27 10.5 0.0 1.6 1 1 0 1 1 1 0 Kinase-like Amidase PF01425.21 KXL49542.1 - 2.1e-93 313.7 0.0 7.2e-93 312.0 0.0 1.7 1 1 0 1 1 1 1 Amidase SAC3_GANP PF03399.16 KXL49543.1 - 3e-99 332.1 1.2 3.5e-99 331.9 1.2 1.1 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KXL49543.1 - 0.13 12.3 0.1 0.33 10.9 0.1 1.6 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family DUF2841 PF11001.8 KXL49544.1 - 7e-22 77.8 1.3 1.1e-21 77.1 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) ABC_membrane PF00664.23 KXL49545.1 - 2.6e-85 286.4 22.1 7.7e-44 150.4 9.7 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXL49545.1 - 2.1e-52 177.3 0.2 2e-30 106.1 0.0 3.0 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 KXL49545.1 - 9.1e-09 35.1 6.6 0.0019 17.7 0.2 4.1 2 2 0 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KXL49545.1 - 1.7e-05 24.9 0.5 0.23 11.6 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXL49545.1 - 8.7e-05 22.5 0.2 0.032 14.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KXL49545.1 - 0.00036 20.2 0.2 0.35 10.7 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KXL49545.1 - 0.0091 16.4 4.5 0.62 10.4 0.2 3.1 2 1 0 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 KXL49545.1 - 0.025 14.4 4.1 2.3 7.9 0.0 3.9 5 0 0 5 5 5 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KXL49545.1 - 0.029 14.9 4.8 0.33 11.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain GTP_EFTU PF00009.27 KXL49545.1 - 0.05 13.1 0.1 2.7 7.5 0.0 2.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF87 PF01935.17 KXL49545.1 - 0.057 13.5 2.2 2.1 8.4 0.0 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_22 PF13401.6 KXL49545.1 - 0.12 12.6 2.6 14 5.9 0.2 3.2 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KXL49545.1 - 0.22 11.2 1.5 3.4 7.4 0.1 2.9 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KXL49545.1 - 0.64 10.1 4.2 8.9 6.3 0.1 2.8 3 0 0 3 3 2 0 Dynamin family Dioxygenase_C PF00775.21 KXL49546.1 - 3.4e-43 147.2 0.1 4.3e-43 146.9 0.1 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KXL49546.1 - 3.9e-18 65.1 0.3 3.5e-17 62.0 0.1 2.2 2 0 0 2 2 2 1 Catechol dioxygenase N terminus SpaA PF17802.1 KXL49546.1 - 0.00018 21.8 0.0 0.00037 20.8 0.0 1.5 1 0 0 1 1 1 1 Prealbumin-like fold domain CarboxypepD_reg PF13620.6 KXL49546.1 - 0.0049 17.1 0.0 0.022 15.0 0.0 2.0 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain PhyH PF05721.13 KXL49548.1 - 3.7e-11 43.7 0.0 7.4e-11 42.7 0.0 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) CBFD_NFYB_HMF PF00808.23 KXL49549.1 - 3.4e-19 68.9 0.5 4.7e-19 68.4 0.5 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXL49549.1 - 1e-14 55.0 0.2 1.7e-14 54.3 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KXL49549.1 - 0.046 14.0 0.3 0.094 13.0 0.1 1.6 2 0 0 2 2 2 0 CENP-S associating Centromere protein X HGTP_anticodon PF03129.20 KXL49550.1 - 9.8e-21 73.7 0.1 3.3e-20 72.0 0.1 2.0 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KXL49550.1 - 1.8e-07 31.3 0.0 4.4e-06 26.8 0.0 2.5 3 0 0 3 3 3 1 tRNA synthetase class II core domain (G, H, P, S and T) R3H PF01424.22 KXL49551.1 - 8.6e-11 41.7 0.1 1.6e-10 40.8 0.1 1.5 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 KXL49551.1 - 8.1e-08 32.0 0.0 1.4e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1856 PF08983.10 KXL49551.1 - 0.11 12.7 3.1 0.8 10.0 0.1 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1856) RRM_2 PF04059.12 KXL49551.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif 2 Brix PF04427.18 KXL49552.1 - 9.4e-24 84.6 0.5 1.4e-23 84.0 0.0 1.6 2 0 0 2 2 2 1 Brix domain DUF3523 PF12037.8 KXL49552.1 - 0.055 12.9 8.3 0.082 12.3 8.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) Histone PF00125.24 KXL49553.1 - 7.7e-17 61.9 0.0 9.6e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KXL49553.1 - 1.4e-12 47.1 0.2 3.1e-12 46.0 0.2 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KXL49553.1 - 1.3e-05 25.4 0.0 2.1e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PDT PF00800.18 KXL49554.1 - 2.8e-59 200.0 0.0 3.6e-59 199.7 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 KXL49554.1 - 0.0012 18.6 0.0 0.003 17.3 0.0 1.7 1 0 0 1 1 1 1 ACT domain eRF1_2 PF03464.15 KXL49555.1 - 1.2e-48 164.8 0.1 1.9e-48 164.2 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KXL49555.1 - 6.1e-39 133.0 0.1 1.3e-38 131.9 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KXL49555.1 - 4.6e-21 75.2 0.0 7.4e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 KXL49555.1 - 9.6e-11 42.1 0.0 1.7e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 KXL49555.1 - 2.5e-09 37.5 0.1 4e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor Rad50_zn_hook PF04423.14 KXL49555.1 - 0.053 13.4 0.2 20 5.1 0.0 3.4 3 0 0 3 3 3 0 Rad50 zinc hook motif DUF3440 PF11922.8 KXL49555.1 - 0.15 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) Lipase_GDSL_2 PF13472.6 KXL49557.1 - 4.3e-05 24.0 0.2 7.2e-05 23.3 0.2 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXL49557.1 - 8.1e-05 22.7 0.0 0.00012 22.1 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Nicastrin PF05450.15 KXL49558.1 - 0.025 14.0 0.0 0.025 14.0 0.0 1.0 1 0 0 1 1 1 0 Nicastrin Peptidase_S9 PF00326.21 KXL49559.1 - 1.8e-47 161.6 2.2 1.5e-45 155.3 2.2 2.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KXL49559.1 - 5.2e-06 26.2 2.6 0.00089 18.9 0.4 2.3 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 KXL49559.1 - 2e-05 24.4 0.4 0.00034 20.3 0.2 2.3 2 0 0 2 2 2 1 Putative esterase DUF2920 PF11144.8 KXL49559.1 - 0.00045 19.5 0.0 0.0074 15.5 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2920) Abhydrolase_3 PF07859.13 KXL49559.1 - 0.069 13.0 0.0 0.34 10.7 0.0 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold Pkinase PF00069.25 KXL49560.1 - 3e-34 118.6 0.0 8.9e-19 67.9 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXL49560.1 - 3.6e-14 52.7 0.0 2.2e-13 50.1 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXL49560.1 - 0.00017 21.6 0.0 0.0004 20.4 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family MAJIN PF15077.6 KXL49560.1 - 0.24 11.2 0.7 0.39 10.5 0.7 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein Proteasom_Rpn13 PF04683.13 KXL49562.1 - 7.1e-26 90.6 0.0 1.1e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 KXL49562.1 - 1.3e-11 44.6 0.1 2e-10 40.8 0.1 2.2 1 1 0 1 1 1 1 UCH-binding domain Chorion_3 PF05387.11 KXL49562.1 - 0.083 12.5 1.3 0.13 11.9 1.3 1.2 1 0 0 1 1 1 0 Chorion family 3 AAA_16 PF13191.6 KXL49563.1 - 9.5e-06 26.1 0.1 1e-05 26.0 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KXL49563.1 - 0.00025 21.5 0.0 0.00038 20.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KXL49563.1 - 0.003 17.8 0.0 0.0049 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF853 PF05872.12 KXL49563.1 - 0.0036 16.0 0.0 0.0038 15.9 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) AAA_30 PF13604.6 KXL49563.1 - 0.0055 16.4 0.0 0.0069 16.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXL49563.1 - 0.0083 16.4 0.0 0.01 16.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KXL49563.1 - 0.0084 15.9 0.0 0.0094 15.7 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.12 KXL49563.1 - 0.009 15.9 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 KXL49563.1 - 0.011 16.0 0.1 0.014 15.7 0.1 1.2 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 KXL49563.1 - 0.02 14.4 0.1 0.024 14.1 0.1 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_21 PF13304.6 KXL49563.1 - 0.048 13.5 0.0 0.058 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF815 PF05673.13 KXL49563.1 - 0.05 12.8 0.0 0.052 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TrwB_AAD_bind PF10412.9 KXL49563.1 - 0.056 12.4 0.0 0.061 12.2 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.14 KXL49563.1 - 0.071 13.1 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KXL49563.1 - 0.081 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ResIII PF04851.15 KXL49563.1 - 0.16 11.9 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit EF1_GNE PF00736.19 KXL49564.1 - 9.6e-34 115.4 1.3 1.8e-33 114.5 1.3 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KXL49564.1 - 2.2e-14 53.6 9.6 2.2e-14 53.6 9.6 2.3 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C PF00043.25 KXL49564.1 - 0.0058 16.8 1.3 0.018 15.3 0.0 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXL49564.1 - 0.01 16.0 0.2 0.075 13.2 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Cwf_Cwc_15 PF04889.12 KXL49564.1 - 0.016 14.9 2.9 0.023 14.5 2.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein MMgT PF10270.9 KXL49565.1 - 9.4e-33 112.6 0.0 1.2e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 Membrane magnesium transporter MutS_V PF00488.21 KXL49566.1 - 1.2e-48 165.7 0.0 2.3e-48 164.8 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXL49566.1 - 6.5e-21 75.4 0.0 2.4e-20 73.6 0.0 2.0 1 1 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 KXL49566.1 - 0.04 14.3 0.0 0.093 13.1 0.0 1.6 1 0 0 1 1 1 0 MutS family domain IV T3SS_ATPase_C PF18269.1 KXL49566.1 - 0.091 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 T3SS EscN ATPase C-terminal domain AAA_29 PF13555.6 KXL49566.1 - 0.17 11.6 0.0 0.45 10.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ribosomal_L6e PF01159.19 KXL49567.1 - 3.2e-36 124.3 0.2 4.4e-36 123.8 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e MlrC_C PF07171.12 KXL49568.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 MlrC C-terminus AXE1 PF05448.12 KXL49569.1 - 2.1e-10 39.8 0.0 0.00021 20.1 0.0 3.0 3 0 0 3 3 3 3 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 KXL49569.1 - 4.7e-08 33.0 0.0 7.6e-08 32.3 0.0 1.4 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 KXL49569.1 - 3.5e-05 23.8 0.0 0.0099 15.8 0.0 2.1 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 KXL49569.1 - 0.00043 19.8 0.0 0.033 13.7 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KXL49569.1 - 0.0011 18.3 0.0 0.013 14.8 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 KXL49569.1 - 0.074 12.6 0.0 0.53 9.8 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family FSH1 PF03959.13 KXL49569.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF5572 PF17733.1 KXL49570.1 - 2.3e-23 81.8 2.3 3.8e-23 81.1 2.3 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5572) LSM14 PF12701.7 KXL49571.1 - 5.2e-29 100.2 0.2 9.3e-29 99.3 0.2 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 KXL49571.1 - 4.6e-14 53.2 3.6 4.6e-14 53.2 3.6 2.9 2 1 0 2 2 2 1 FDF domain SM-ATX PF14438.6 KXL49571.1 - 0.0002 21.4 0.0 0.0004 20.5 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.22 KXL49571.1 - 0.057 13.1 0.0 0.092 12.5 0.0 1.3 1 0 0 1 1 1 0 LSM domain eIF-4B PF06273.11 KXL49573.1 - 0.3 10.1 0.0 0.34 9.9 0.0 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B DDE_1 PF03184.19 KXL49574.1 - 3.7e-06 26.7 0.1 8.3e-06 25.6 0.1 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease E2 PF08199.11 KXL49574.1 - 0.013 15.4 1.6 0.018 15.0 0.3 1.9 2 0 0 2 2 2 0 Bacteriophage E2-like protein DAO_C PF16901.5 KXL49574.1 - 0.038 13.9 1.6 0.12 12.3 0.2 2.1 2 1 0 2 2 2 0 C-terminal domain of alpha-glycerophosphate oxidase Pro-kuma_activ PF09286.11 KXL49575.1 - 1.1e-42 145.6 0.0 8.3e-41 139.6 0.0 2.3 2 0 0 2 2 2 2 Pro-kumamolisin, activation domain COesterase PF00135.28 KXL49577.1 - 4e-26 92.0 0.1 4.6e-26 91.8 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXL49577.1 - 0.001 19.0 0.0 0.0012 18.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXL49577.1 - 0.0012 18.4 0.0 0.0012 18.4 0.0 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase family 3Beta_HSD PF01073.19 KXL49578.1 - 4.6e-24 84.9 0.0 1.1e-23 83.6 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXL49578.1 - 6.2e-10 38.9 0.0 1.2e-09 38.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KXL49578.1 - 3.1e-08 33.1 1.1 3.6e-06 26.4 0.0 2.4 3 0 0 3 3 3 2 Male sterility protein NAD_binding_10 PF13460.6 KXL49578.1 - 6.3e-07 29.5 0.0 1.4e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXL49578.1 - 0.00015 21.1 0.0 0.00022 20.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KXL49578.1 - 0.00024 21.0 0.0 0.00049 20.1 0.0 1.4 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KXL49578.1 - 0.00041 19.9 0.0 0.00061 19.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KXL49578.1 - 0.054 12.6 0.0 0.14 11.2 0.0 1.8 1 1 0 1 1 1 0 RmlD substrate binding domain ADH_zinc_N_2 PF13602.6 KXL49579.1 - 7.5e-25 88.5 0.0 1.1e-24 88.0 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXL49579.1 - 1.1e-12 48.1 0.0 1.7e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PALP PF00291.25 KXL49579.1 - 0.042 13.3 0.1 0.058 12.8 0.1 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme DUF2014 PF09427.10 KXL49580.1 - 3.1e-96 321.8 0.4 5.2e-96 321.0 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.26 KXL49580.1 - 4.6e-15 55.3 0.9 9.9e-15 54.3 0.9 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TMF_DNA_bd PF12329.8 KXL49580.1 - 0.53 10.3 2.9 0.36 10.9 0.6 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Transferase PF02458.15 KXL49581.1 - 0.11 11.1 0.0 0.12 11.0 0.0 1.0 1 0 0 1 1 1 0 Transferase family p450 PF00067.22 KXL49582.1 - 2.8e-73 247.3 0.0 3.6e-73 246.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_1 PF00561.20 KXL49583.1 - 3.8e-15 56.2 0.0 9.4e-10 38.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXL49583.1 - 1e-14 54.4 0.0 1.6e-13 50.5 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXL49583.1 - 1.1e-10 42.6 0.0 1.5e-10 42.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KXL49583.1 - 0.0011 18.8 0.0 0.12 12.2 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 KXL49583.1 - 0.046 13.3 0.0 0.094 12.3 0.0 1.5 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 KXL49583.1 - 0.072 12.6 0.0 2.3 7.7 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KXL49583.1 - 0.095 12.2 0.1 4.6 6.6 0.0 2.5 2 1 1 3 3 3 0 Prolyl oligopeptidase family DUF1100 PF06500.11 KXL49583.1 - 0.13 11.1 0.0 0.26 10.1 0.0 1.4 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1100) DUF3141 PF11339.8 KXL49583.1 - 0.13 10.7 0.0 0.2 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) Sugar_tr PF00083.24 KXL49584.1 - 4.1e-36 124.8 21.1 2.3e-23 82.8 3.5 2.0 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXL49584.1 - 6.6e-18 64.7 38.5 9.5e-13 47.8 21.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Transgly_assoc PF04226.13 KXL49584.1 - 0.24 11.7 0.0 0.24 11.7 0.0 4.6 5 1 1 6 6 6 0 Transglycosylase associated protein SART-1 PF03343.13 KXL49587.1 - 1.9e-142 476.1 45.8 2.3e-142 475.8 45.8 1.0 1 0 0 1 1 1 1 SART-1 family Spore_permease PF03845.13 KXL49588.1 - 0.046 12.5 0.0 0.047 12.5 0.0 1.0 1 0 0 1 1 1 0 Spore germination protein Trp_syntA PF00290.20 KXL49589.1 - 5e-89 297.6 0.0 7.1e-89 297.1 0.0 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 KXL49589.1 - 9.2e-40 136.9 0.8 1.8e-39 135.9 0.8 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zinc_ribbon_10 PF10058.9 KXL49590.1 - 7.2e-20 70.5 0.2 1.6e-19 69.4 0.2 1.6 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein PHM7_cyt PF14703.6 KXL49590.1 - 0.019 15.2 0.0 0.045 14.0 0.0 1.6 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter CSN7a_helixI PF18392.1 KXL49590.1 - 0.032 14.1 0.1 0.087 12.7 0.1 1.6 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain DivIC PF04977.15 KXL49590.1 - 0.049 13.4 0.9 0.16 11.8 0.1 2.0 2 0 0 2 2 2 0 Septum formation initiator Rubredoxin_2 PF18073.1 KXL49590.1 - 2.6 7.9 8.8 0.24 11.1 3.0 2.1 2 0 0 2 2 2 0 Rubredoxin metal binding domain Haem_degrading PF03928.14 KXL49591.1 - 1.3e-28 99.4 0.2 1.6e-28 99.2 0.2 1.1 1 0 0 1 1 1 1 Haem-degrading OAM_dimer PF16554.5 KXL49591.1 - 0.14 12.6 0.0 0.24 11.9 0.0 1.4 1 0 0 1 1 1 0 Dimerisation domain of d-ornithine 4,5-aminomutase PIEZO PF15917.5 KXL49592.1 - 0.16 11.4 0.4 0.38 10.2 0.4 1.5 1 0 0 1 1 1 0 Piezo CFEM PF05730.11 KXL49593.1 - 9.2e-06 25.7 1.3 9.2e-06 25.7 1.3 2.7 2 0 0 2 2 2 1 CFEM domain DUF3328 PF11807.8 KXL49594.1 - 0.23 11.2 1.1 7.4 6.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) ATP_sub_h PF10775.9 KXL49595.1 - 9.5e-24 83.2 1.4 1.7e-23 82.4 1.4 1.4 1 0 0 1 1 1 1 ATP synthase complex subunit h TFIIB PF00382.19 KXL49596.1 - 1.1e-35 121.4 0.3 3.4e-19 68.7 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KXL49596.1 - 2.4e-11 42.9 0.1 4.7e-11 42.0 0.1 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_5 PF01022.20 KXL49596.1 - 0.0011 18.7 0.0 0.21 11.5 0.0 2.9 3 0 0 3 3 3 1 Bacterial regulatory protein, arsR family zf-ribbon_3 PF13248.6 KXL49596.1 - 0.0094 15.3 0.5 0.04 13.3 0.1 2.2 2 0 0 2 2 2 1 zinc-ribbon domain Cyclin_C PF02984.19 KXL49596.1 - 0.011 15.8 0.1 4.1 7.5 0.3 2.3 2 0 0 2 2 2 0 Cyclin, C-terminal domain ArfGap PF01412.18 KXL49596.1 - 0.055 13.5 0.0 0.098 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf RB_B PF01857.20 KXL49596.1 - 0.066 13.2 0.0 0.33 11.0 0.0 2.0 1 1 1 2 2 2 0 Retinoblastoma-associated protein B domain TFIIB_C_1 PF18542.1 KXL49596.1 - 0.08 13.0 0.1 16 5.6 0.0 2.4 2 0 0 2 2 2 0 Transcription factor IIB C-terminal module 1 Ribosomal_S27e PF01667.17 KXL49596.1 - 0.14 11.9 0.1 0.3 10.8 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein S27 HTH_36 PF13730.6 KXL49596.1 - 0.22 11.5 0.7 8.5 6.4 0.0 3.4 5 0 0 5 5 5 0 Helix-turn-helix domain zinc_ribbon_10 PF10058.9 KXL49596.1 - 0.25 11.1 1.4 0.89 9.3 1.4 2.0 1 1 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein LisH_TPL PF17814.1 KXL49597.1 - 0.044 13.5 0.4 0.83 9.4 0.1 2.5 2 0 0 2 2 2 0 LisH-like dimerisation domain COesterase PF00135.28 KXL49598.1 - 3e-59 201.3 0.0 6.5e-59 200.2 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KXL49598.1 - 0.00071 19.1 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KXL49598.1 - 0.00083 19.3 0.1 0.0033 17.3 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Actin PF00022.19 KXL49599.1 - 5.6e-24 84.5 0.2 1.1e-19 70.4 0.0 3.2 3 1 0 3 3 3 2 Actin MreB_Mbl PF06723.13 KXL49599.1 - 0.00026 19.9 0.0 0.29 9.9 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Bud13 PF09736.9 KXL49599.1 - 1.3 9.4 5.2 2.2 8.7 5.2 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex His_Phos_2 PF00328.22 KXL49600.1 - 2.3e-107 359.7 1.0 3.7e-107 359.0 1.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KXL49600.1 - 8e-37 125.3 0.0 2e-36 124.0 0.0 1.6 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KXL49600.1 - 3.6e-06 26.7 0.0 7.3e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Utp21 PF04192.12 KXL49601.1 - 1.6e-70 237.3 0.2 2.2e-70 236.8 0.2 1.1 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 KXL49601.1 - 1.6e-13 50.7 0.0 0.015 15.6 0.0 6.4 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXL49601.1 - 2.4e-12 47.2 22.5 0.16 12.9 0.0 9.1 9 0 0 9 9 9 4 WD domain, G-beta repeat SEP PF08059.13 KXL49601.1 - 0.16 12.5 0.2 2.3 8.8 0.0 2.3 2 0 0 2 2 2 0 SEP domain Trimer_CC PF08954.11 KXL49601.1 - 0.69 9.5 2.2 1.6 8.3 2.2 1.6 1 0 0 1 1 1 0 Trimerisation motif AAR2 PF05282.11 KXL49602.1 - 1.6e-84 284.3 0.1 2.5e-84 283.7 0.1 1.3 1 0 0 1 1 1 1 AAR2 protein Tropomyosin_1 PF12718.7 KXL49605.1 - 0.00015 21.9 14.7 0.00015 21.9 14.7 4.9 3 1 2 5 5 5 1 Tropomyosin like Lebercilin PF15619.6 KXL49605.1 - 0.0013 18.5 20.6 0.0013 18.5 20.6 4.8 4 1 1 5 5 5 2 Ciliary protein causing Leber congenital amaurosis disease Filament PF00038.21 KXL49605.1 - 0.0023 17.6 9.5 0.0023 17.6 9.5 4.2 4 1 1 5 5 5 1 Intermediate filament protein TRAF_BIRC3_bd PF16673.5 KXL49605.1 - 0.1 12.4 13.5 0.43 10.4 0.7 5.0 3 2 2 5 5 5 0 TNF receptor-associated factor BIRC3 binding domain ATG16 PF08614.11 KXL49605.1 - 0.27 11.4 63.0 2.5 8.3 9.0 5.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 KXL49605.1 - 0.42 10.6 18.6 0.059 13.4 4.8 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 KXL49605.1 - 2 8.6 27.6 0.12 12.6 6.2 3.5 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family LOH1CR12 PF10158.9 KXL49605.1 - 2.9 7.9 7.8 1.1 9.3 0.3 2.6 2 1 0 2 2 2 0 Tumour suppressor protein FlaC_arch PF05377.11 KXL49605.1 - 3.5 8.1 27.1 2 8.9 0.4 6.4 5 2 1 7 7 7 0 Flagella accessory protein C (FlaC) Sec2p PF06428.11 KXL49605.1 - 8.9 6.4 41.3 0.17 11.9 0.9 6.0 2 1 3 6 6 6 0 GDP/GTP exchange factor Sec2p NPV_P10 PF05531.12 KXL49605.1 - 9.2 6.8 13.8 15 6.1 0.4 3.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 KXL49605.1 - 9.5 5.5 45.8 1.3 8.3 7.5 4.1 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) DUF659 PF04937.15 KXL49606.1 - 0.053 13.4 0.0 0.084 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) Amidohydro_1 PF01979.20 KXL49608.1 - 3.3e-15 56.2 0.0 3.4e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXL49608.1 - 8.4e-12 45.3 0.0 9e-12 45.2 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Glyco_hydro_10 PF00331.20 KXL49610.1 - 4.2e-74 249.5 0.0 4.9e-74 249.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DUF3394 PF11874.8 KXL49610.1 - 0.21 11.3 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) F-box PF00646.33 KXL49611.1 - 0.00036 20.3 0.1 0.00067 19.5 0.1 1.4 1 0 0 1 1 1 1 F-box domain Peptidase_S28 PF05577.12 KXL49612.1 - 9.8e-45 153.1 0.4 8.7e-44 150.0 0.4 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase S28 DUF2920 PF11144.8 KXL49612.1 - 0.23 10.6 0.1 0.38 9.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Asp PF00026.23 KXL49613.1 - 2.7e-52 178.2 2.2 4.1e-52 177.5 2.2 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXL49613.1 - 7.4e-12 45.9 6.2 1.3e-09 38.6 1.6 3.7 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KXL49613.1 - 0.0029 18.2 1.0 8 7.2 0.0 3.8 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KXL49613.1 - 0.032 14.8 0.0 13 6.4 0.1 3.4 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF5634_N PF18672.1 KXL49617.1 - 0.15 11.8 0.0 0.79 9.5 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5634) Glyco_transf_90 PF05686.12 KXL49618.1 - 1.4e-25 90.1 0.2 1.8e-25 89.7 0.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 PRIMA1 PF16101.5 KXL49618.1 - 1.1 9.3 3.7 2 8.5 3.7 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 TFIIE_alpha PF02002.17 KXL49619.1 - 1.6e-09 37.5 0.2 3.9e-08 33.1 0.2 2.6 1 1 0 1 1 1 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.12 KXL49619.1 - 0.031 13.8 0.1 0.099 12.2 0.1 1.9 1 0 0 1 1 1 0 TFIIB zinc-binding SR1P PF13790.6 KXL49619.1 - 0.061 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 SR1 protein HTH_Crp_2 PF13545.6 KXL49619.1 - 0.096 12.7 0.0 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain zf-FPG_IleRS PF06827.14 KXL49619.1 - 0.31 10.9 3.9 0.62 10.0 0.1 2.5 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-RRN7 PF11781.8 KXL49619.1 - 0.52 10.1 2.3 8.5 6.2 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Zn-ribbon_8 PF09723.10 KXL49619.1 - 2.2 8.5 4.2 27 5.0 0.5 2.7 1 1 0 2 2 2 0 Zinc ribbon domain RNA_pol_3_Rpc31 PF11705.8 KXL49619.1 - 3 8.0 20.7 0.81 9.9 14.8 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Ferlin_C PF16165.5 KXL49619.1 - 6.7 6.6 6.6 1.2 9.1 1.3 2.2 2 0 0 2 2 2 0 Ferlin C-terminus Glyco_hydro_63 PF03200.16 KXL49620.1 - 3.6e-09 35.9 7.1 1.3e-07 30.8 0.5 2.9 2 1 0 2 2 2 2 Glycosyl hydrolase family 63 C-terminal domain Trehalase PF01204.18 KXL49620.1 - 2.2e-06 26.8 0.4 0.011 14.6 0.0 2.1 2 0 0 2 2 2 2 Trehalase Gly_transf_sug PF04488.15 KXL49621.1 - 5e-18 65.5 0.0 9.5e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KXL49621.1 - 0.052 12.9 0.2 0.12 11.7 0.2 1.6 1 1 0 1 1 1 0 Capsular polysaccharide synthesis protein ICMT PF04140.14 KXL49622.1 - 1.6e-28 98.9 0.4 3.6e-28 97.8 0.4 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KXL49622.1 - 1.2e-12 48.1 1.4 1.2e-12 48.1 1.4 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 KXL49622.1 - 2.6e-05 23.9 0.2 3.5e-05 23.4 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 KXL49622.1 - 0.00067 19.2 3.0 0.00067 19.2 3.0 1.9 1 1 1 2 2 2 1 NnrU protein Cep57_MT_bd PF06657.13 KXL49623.1 - 0.022 15.2 2.7 0.085 13.3 2.7 2.0 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 CAP59_mtransfer PF11735.8 KXL49624.1 - 7.4e-71 238.6 0.0 9.8e-71 238.2 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DUF2275 PF10039.9 KXL49624.1 - 0.05 13.7 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) Ank_2 PF12796.7 KXL49625.1 - 2.9e-18 66.2 0.2 5.9e-09 36.4 0.0 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXL49625.1 - 1.8e-14 53.6 0.1 2.1e-06 27.9 0.0 3.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXL49625.1 - 5.4e-09 36.4 0.1 5.3e-07 30.1 0.1 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXL49625.1 - 1.6e-06 28.0 0.0 0.089 13.4 0.0 4.2 4 1 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KXL49625.1 - 0.002 18.5 0.0 0.3 11.6 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat adh_short_C2 PF13561.6 KXL49627.1 - 3.3e-55 187.2 0.0 4.9e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL49627.1 - 2.7e-44 151.0 0.1 3.4e-44 150.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL49627.1 - 7.7e-12 45.5 0.1 1.1e-11 45.0 0.1 1.2 1 0 0 1 1 1 1 KR domain HATPase_c PF02518.26 KXL49627.1 - 0.0035 17.8 0.0 0.014 15.9 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 2-Hacid_dh_C PF02826.19 KXL49627.1 - 0.0087 15.4 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain LDcluster4 PF18306.1 KXL49627.1 - 0.025 14.2 0.7 0.21 11.1 0.2 2.1 2 0 0 2 2 2 0 SLOG cluster4 family Epimerase PF01370.21 KXL49627.1 - 0.028 13.9 0.0 0.052 13.0 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 KXL49627.1 - 0.036 14.8 0.0 0.064 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ADH_N PF08240.12 KXL49629.1 - 2e-26 92.0 2.2 3.5e-26 91.2 2.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXL49629.1 - 8.6e-14 51.6 0.0 1.3e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXL49629.1 - 1.9e-05 24.2 0.2 0.0005 19.6 0.1 2.2 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus PKI PF02827.16 KXL49629.1 - 0.051 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor ADH_zinc_N_2 PF13602.6 KXL49629.1 - 0.058 14.4 0.0 0.12 13.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 KXL49630.1 - 3.6e-45 154.4 0.0 4.5e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL49630.1 - 3.5e-31 108.2 0.0 5.1e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL49630.1 - 4.2e-10 39.8 0.1 4.2e-09 36.6 0.1 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL49630.1 - 0.0019 17.7 0.0 0.0033 16.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ACBP PF00887.19 KXL49631.1 - 2e-22 79.2 0.0 3.9e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein NINJA_B PF16136.5 KXL49631.1 - 0.59 10.5 11.2 0.043 14.2 4.5 2.2 2 0 0 2 2 2 0 Putative nuclear localisation signal MFS_1 PF07690.16 KXL49632.1 - 8.2e-42 143.4 32.0 8.2e-42 143.4 32.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Cellulase PF00150.18 KXL49634.1 - 1.6e-29 103.2 0.8 2e-29 102.9 0.8 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MFS_1 PF07690.16 KXL49635.1 - 1.3e-41 142.8 38.9 8.9e-41 140.0 40.0 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXL49635.1 - 1.5e-15 56.7 12.3 2.3e-15 56.0 12.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1430 PF07242.11 KXL49635.1 - 0.024 14.9 0.5 0.024 14.9 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) DUF3948 PF13134.6 KXL49635.1 - 3.1 7.6 8.6 7.7 6.3 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3948) Sugar_tr PF00083.24 KXL49636.1 - 2.3e-90 303.7 15.6 2.7e-90 303.4 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL49636.1 - 1.6e-25 89.8 19.4 2e-22 79.6 8.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXL49636.1 - 9.6e-05 21.1 2.3 9.6e-05 21.1 2.3 2.6 3 0 0 3 3 3 2 MFS/sugar transport protein ABC2_membrane_2 PF12679.7 KXL49636.1 - 2.6 7.3 10.7 0.17 11.1 4.8 2.1 2 1 0 2 2 2 0 ABC-2 family transporter protein dCMP_cyt_deam_1 PF00383.23 KXL49637.1 - 1.1e-10 41.3 0.2 1.7e-10 40.6 0.2 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXL49637.1 - 1.2e-07 31.5 0.1 1.6e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC_N PF08210.11 KXL49637.1 - 0.00019 21.4 0.1 0.00021 21.2 0.1 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain SNAD4 PF18750.1 KXL49637.1 - 0.0029 17.7 0.6 0.005 17.0 0.6 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 KXL49637.1 - 0.0062 16.6 0.4 0.0089 16.1 0.4 1.2 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 KXL49637.1 - 0.01 15.9 0.4 0.015 15.4 0.4 1.3 1 0 0 1 1 1 0 APOBEC2 APOBEC3 PF18771.1 KXL49637.1 - 0.011 15.9 0.4 0.017 15.2 0.4 1.2 1 0 0 1 1 1 0 APOBEC3 NAD2 PF18782.1 KXL49637.1 - 0.034 14.3 0.2 0.045 13.9 0.2 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 XOO_2897-deam PF14440.6 KXL49637.1 - 0.089 12.9 0.2 0.18 11.9 0.3 1.6 1 1 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase Bd3614-deam PF14439.6 KXL49637.1 - 0.14 12.2 1.2 0.27 11.3 1.0 1.5 1 1 0 1 1 1 0 Bd3614-like deaminase 4HBT_2 PF13279.6 KXL49638.1 - 9.4e-10 39.0 0.0 1.5e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Catalase PF00199.19 KXL49639.1 - 1.4e-07 31.0 0.1 2.6e-07 30.1 0.1 1.4 1 1 0 1 1 1 1 Catalase SseB_C PF14581.6 KXL49639.1 - 0.018 15.1 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 SseB protein C-terminal domain Peptidase_S10 PF00450.22 KXL49641.1 - 3.3e-88 296.9 4.9 4.3e-88 296.5 4.9 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Polysacc_deac_1 PF01522.21 KXL49642.1 - 6e-10 39.1 0.0 1.1e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase COX4 PF02936.14 KXL49643.1 - 1.7e-41 141.5 0.0 1.9e-41 141.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV LapA_dom PF06305.11 KXL49644.1 - 0.00064 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain Miga PF10265.9 KXL49644.1 - 0.24 10.3 0.0 0.26 10.2 0.0 1.0 1 0 0 1 1 1 0 Mitoguardin XRCC4 PF06632.12 KXL49648.1 - 3.1e-08 32.9 1.8 5.5e-08 32.0 1.8 1.4 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF2730 PF10805.8 KXL49648.1 - 0.065 13.3 0.5 0.17 12.0 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) SlyX PF04102.12 KXL49648.1 - 0.13 12.9 6.8 0.18 12.5 5.4 1.9 1 1 0 1 1 1 0 SlyX TMPIT PF07851.13 KXL49648.1 - 0.29 10.3 2.2 0.45 9.7 2.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein AA_permease_2 PF13520.6 KXL49652.1 - 1.7e-45 155.6 56.7 2.2e-45 155.3 56.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXL49652.1 - 1.1e-19 70.5 44.4 1.6e-19 69.9 44.4 1.2 1 0 0 1 1 1 1 Amino acid permease Meth_synt_2 PF01717.18 KXL49653.1 - 3.3e-11 43.0 0.0 4.2e-06 26.3 0.0 2.6 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KXL49653.1 - 0.004 16.7 0.2 0.24 10.9 0.1 2.6 3 0 0 3 3 3 1 Cobalamin-independent synthase, N-terminal domain CKS PF01111.19 KXL49653.1 - 0.12 12.7 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase regulatory subunit 6PF2K PF01591.18 KXL49654.1 - 1.7e-50 171.4 0.0 2.8e-50 170.7 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KXL49654.1 - 1.3e-27 96.8 0.0 9.1e-22 77.7 0.0 2.5 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) DUF5128 PF17170.4 KXL49654.1 - 0.1 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 6-bladed beta-propeller Podoplanin PF05808.11 KXL49655.1 - 3.3e-06 27.3 2.5 4.9e-06 26.7 2.5 1.2 1 0 0 1 1 1 1 Podoplanin DUF4690 PF15756.5 KXL49655.1 - 0.00062 20.3 0.9 0.0015 19.1 0.9 1.7 1 0 0 1 1 1 1 Small Novel Rich in Cartilage PTP_tm PF18861.1 KXL49655.1 - 0.00078 19.5 4.6 0.0012 18.8 4.5 1.3 1 1 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J Stevor PF17410.2 KXL49655.1 - 0.0038 16.8 0.6 0.0052 16.4 0.6 1.1 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame Glycophorin_A PF01102.18 KXL49655.1 - 0.011 15.9 0.8 0.019 15.2 0.5 1.4 1 1 0 1 1 1 0 Glycophorin A TMEM65 PF10507.9 KXL49655.1 - 0.013 15.5 3.3 0.022 14.7 3.3 1.3 1 0 0 1 1 1 0 Transmembrane protein 65 DAP10 PF07213.11 KXL49655.1 - 0.013 15.4 0.2 0.035 14.1 0.2 1.7 1 0 0 1 1 1 0 DAP10 membrane protein TMEM154 PF15102.6 KXL49655.1 - 0.014 15.3 0.4 0.022 14.6 0.4 1.3 1 0 0 1 1 1 0 TMEM154 protein family Amnionless PF14828.6 KXL49655.1 - 0.022 13.6 0.0 0.03 13.2 0.0 1.1 1 0 0 1 1 1 0 Amnionless CD34_antigen PF06365.12 KXL49655.1 - 0.029 14.0 0.1 0.037 13.6 0.1 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family SKG6 PF08693.10 KXL49655.1 - 0.031 13.7 2.9 0.068 12.6 2.9 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF5305 PF17231.2 KXL49655.1 - 0.046 13.1 0.2 0.077 12.4 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF2613 PF11021.8 KXL49655.1 - 0.07 13.3 0.2 0.07 13.3 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2613) DUF347 PF03988.12 KXL49655.1 - 0.18 12.1 1.4 0.41 10.9 1.4 1.6 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Syndecan PF01034.20 KXL49655.1 - 0.22 11.4 1.4 0.41 10.6 1.4 1.3 1 0 0 1 1 1 0 Syndecan domain RIFIN PF02009.16 KXL49655.1 - 0.32 10.8 0.0 0.43 10.4 0.0 1.2 1 0 0 1 1 1 0 Rifin MGC-24 PF05283.11 KXL49655.1 - 0.52 10.8 16.0 1.2 9.6 15.8 1.7 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin vATP-synt_AC39 PF01992.16 KXL49656.1 - 1.2e-104 350.5 0.0 1.3e-104 350.3 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Peptidase_C1_2 PF03051.15 KXL49657.1 - 3.1e-159 530.5 0.0 3.5e-159 530.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 KXL49657.1 - 3.4e-07 30.6 0.1 0.014 15.4 0.0 2.4 2 0 0 2 2 2 2 Papain family cysteine protease GST_N_3 PF13417.6 KXL49658.1 - 1.9e-11 44.2 0.0 3.8e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXL49658.1 - 4.3e-07 30.1 0.1 1e-06 29.0 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXL49658.1 - 0.0075 16.3 0.1 0.019 15.0 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KXL49658.1 - 0.051 14.3 0.0 0.42 11.4 0.0 2.1 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain His_Phos_2 PF00328.22 KXL49659.1 - 2.2e-46 158.9 0.0 2.8e-46 158.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) THEG4 PF15834.5 KXL49661.1 - 2.2 8.2 4.9 2.2 8.2 0.6 2.8 2 1 0 2 2 2 0 Testis highly expressed protein 4 TAFII28 PF04719.14 KXL49662.1 - 7.3e-28 96.5 0.0 8.2e-28 96.3 0.0 1.0 1 0 0 1 1 1 1 hTAFII28-like protein conserved region Polyketide_cyc2 PF10604.9 KXL49663.1 - 2.2e-09 37.8 6.1 2.7e-09 37.5 3.8 2.3 1 1 1 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KXL49663.1 - 4.3e-06 27.0 0.2 6.8e-06 26.3 0.2 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Ribosomal_L4 PF00573.22 KXL49665.1 - 2.2e-37 128.6 0.1 3.7e-37 127.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KXL49665.1 - 9.4e-27 92.9 0.1 2.2e-26 91.7 0.1 1.7 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain Hist_deacetyl PF00850.19 KXL49669.1 - 3.7e-79 266.4 0.0 5.8e-79 265.8 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain JAB PF01398.21 KXL49670.1 - 2.7e-33 114.4 0.0 4e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KXL49670.1 - 6.2e-11 42.7 0.3 1.1e-10 41.9 0.1 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KXL49670.1 - 3.5e-07 30.0 0.0 6.8e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF5643 PF18705.1 KXL49672.1 - 0.12 12.3 0.0 11 6.1 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5643) Ank_2 PF12796.7 KXL49673.1 - 5.2e-12 46.2 0.0 7.4e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXL49673.1 - 6e-12 45.8 0.0 3.2e-05 24.4 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXL49673.1 - 1.5e-09 37.9 0.1 5.1e-09 36.2 0.1 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KXL49673.1 - 3.2e-08 33.7 0.0 3.1e-05 24.2 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KXL49673.1 - 9.8e-08 31.7 0.0 0.00078 19.7 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat p450 PF00067.22 KXL49674.1 - 2.8e-43 148.3 0.0 7.1e-43 147.0 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_88 PF07470.13 KXL49675.1 - 3.2e-17 62.7 0.2 3.9e-17 62.3 0.2 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF525 PF04379.14 KXL49675.1 - 0.091 13.0 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 ApaG domain TrkH PF02386.16 KXL49676.1 - 1e-156 522.4 3.8 1e-156 522.4 3.8 2.0 2 0 0 2 2 2 2 Cation transport protein CAP PF00188.26 KXL49677.1 - 9.3e-10 39.4 0.9 4.8e-09 37.1 0.4 2.3 2 1 0 2 2 2 1 Cysteine-rich secretory protein family Sugar_tr PF00083.24 KXL49678.1 - 5.2e-37 127.8 9.1 6.3e-37 127.5 9.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL49678.1 - 1.7e-07 30.5 20.1 3.5e-07 29.5 20.2 1.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL49680.1 - 6e-80 269.3 22.7 7.1e-80 269.1 22.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL49680.1 - 1.1e-29 103.5 49.5 4.7e-27 94.9 24.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXL49680.1 - 7e-05 21.4 1.7 7e-05 21.4 1.7 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Gpr1_Fun34_YaaH PF01184.19 KXL49681.1 - 8.6e-36 123.5 18.5 1e-35 123.2 18.5 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family SKG6 PF08693.10 KXL49683.1 - 3.6e-09 35.9 5.0 1.2e-08 34.2 5.0 1.9 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 KXL49683.1 - 5.5e-05 23.1 0.0 5.5e-05 23.1 0.0 2.6 1 1 2 3 3 3 1 TMEM154 protein family DUF4448 PF14610.6 KXL49683.1 - 0.00043 20.1 0.1 0.00086 19.1 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) CD34_antigen PF06365.12 KXL49683.1 - 0.0022 17.6 0.1 0.006 16.2 0.0 1.7 2 0 0 2 2 2 1 CD34/Podocalyxin family RIFIN PF02009.16 KXL49683.1 - 0.03 14.2 0.4 0.095 12.6 0.4 1.7 1 1 0 1 1 1 0 Rifin EphA2_TM PF14575.6 KXL49683.1 - 0.04 14.8 0.0 0.092 13.6 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.6 KXL49683.1 - 0.074 13.3 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) VSP PF03302.13 KXL49683.1 - 0.088 11.6 8.6 0.13 11.1 8.6 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF3377 PF11857.8 KXL49683.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DPBB_1 PF03330.18 KXL49684.1 - 0.00089 19.5 0.0 0.0009 19.5 0.0 1.2 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KXL49684.1 - 0.091 12.6 0.1 0.096 12.5 0.1 1.2 1 0 0 1 1 1 0 Barwin family KOW PF00467.29 KXL49687.1 - 5.5e-06 26.1 1.9 1.8e-05 24.5 1.9 1.9 1 0 0 1 1 1 1 KOW motif DUF4208 PF13907.6 KXL49687.1 - 0.023 15.1 1.0 0.023 15.1 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) SANT_DAMP1_like PF16282.5 KXL49689.1 - 7.8e-18 64.5 0.4 1.6e-17 63.4 0.4 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 KXL49689.1 - 0.0034 17.3 0.2 0.0096 15.8 0.2 1.7 1 1 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-binding PF00249.31 KXL49689.1 - 0.0063 16.7 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXL49689.1 - 0.13 12.6 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF5527 PF17665.1 KXL49690.1 - 0.071 12.6 0.0 0.078 12.5 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5527) Torus PF16131.5 KXL49692.1 - 3.5e-41 140.3 0.1 1.4e-40 138.3 0.0 2.0 2 0 0 2 2 2 1 Torus domain RRM_1 PF00076.22 KXL49692.1 - 1.1e-06 28.3 0.0 2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 KXL49692.1 - 0.00031 20.7 0.6 0.00031 20.7 0.6 2.0 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 KXL49692.1 - 0.035 14.0 0.8 0.073 13.0 0.8 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nup35_RRM_2 PF14605.6 KXL49692.1 - 0.051 13.6 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Abhydrolase_3 PF07859.13 KXL49693.1 - 1.4e-42 146.0 0.0 1.8e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXL49693.1 - 0.051 12.4 0.0 0.078 11.8 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase COesterase PF00135.28 KXL49693.1 - 0.18 10.6 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family SNF2_N PF00176.23 KXL49694.1 - 1.8e-55 188.1 0.0 2.6e-55 187.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXL49694.1 - 3.1e-16 59.7 0.0 1.1e-15 57.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL49694.1 - 4.1e-10 39.9 0.0 7.5e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 KXL49694.1 - 0.0055 16.4 0.0 0.016 14.9 0.0 1.7 1 0 0 1 1 1 1 SWI2/SNF2 ATPase HDA2-3 PF11496.8 KXL49694.1 - 0.0056 15.9 0.0 0.02 14.1 0.0 2.0 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Cupin_2 PF07883.11 KXL49695.1 - 7.6e-13 48.0 0.2 1.5e-12 47.1 0.2 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KXL49695.1 - 4.6e-07 29.6 0.0 5.6e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Cupin CENP-C_C PF11699.8 KXL49695.1 - 0.015 15.5 0.0 0.059 13.6 0.0 1.9 1 1 0 1 1 1 0 Mif2/CENP-C like Cupin_3 PF05899.12 KXL49695.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cation_efflux PF01545.21 KXL49696.1 - 9.6e-14 51.6 2.6 1.2e-13 51.2 2.6 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KXL49696.1 - 6.5e-11 42.2 0.3 1.4e-10 41.2 0.3 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter STN1_2 PF09170.10 KXL49696.1 - 0.11 12.6 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 CoA_transf_3 PF02515.17 KXL49697.1 - 1.5e-42 146.0 0.0 1.6e-40 139.4 0.0 2.1 2 0 0 2 2 2 2 CoA-transferase family III AbiH PF14253.6 KXL49697.1 - 0.018 15.0 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH AtuA PF07287.11 KXL49698.1 - 2.1e-129 431.2 0.0 2.5e-129 431.0 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA TPMT PF05724.11 KXL49700.1 - 1.4e-36 126.2 0.0 2e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 KXL49700.1 - 2.9e-08 33.7 0.0 4.2e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL49700.1 - 2.3e-07 31.4 0.0 1.2e-06 29.1 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL49700.1 - 2.8e-07 31.1 0.0 6.7e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL49700.1 - 4.3e-07 30.6 0.0 2.2e-06 28.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL49700.1 - 1.3e-06 28.3 0.0 1.1e-05 25.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 KXL49700.1 - 0.061 13.6 0.2 0.16 12.3 0.0 1.8 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase MFS_1 PF07690.16 KXL49701.1 - 3.1e-43 148.1 30.5 3.1e-43 148.1 30.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KXL49701.1 - 0.07 12.4 17.9 0.11 11.8 6.6 2.7 2 1 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB Amidohydro_1 PF01979.20 KXL49703.1 - 1.2e-07 31.4 0.0 2.1e-07 30.6 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 KXL49703.1 - 8.2e-05 22.5 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase HORMA PF02301.18 KXL49704.1 - 6.4e-28 97.8 0.1 7.7e-28 97.5 0.1 1.0 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 KXL49704.1 - 0.0016 18.5 0.4 0.0063 16.5 0.4 2.0 1 1 0 1 1 1 1 Autophagy-related protein 101 GTP_EFTU PF00009.27 KXL49705.1 - 1.2e-50 171.8 0.0 1.9e-50 171.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 KXL49705.1 - 1.3e-37 128.2 3.6 2.3e-37 127.4 3.6 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 KXL49705.1 - 7.4e-20 70.8 0.0 1.5e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus Ras PF00071.22 KXL49705.1 - 3.9e-05 23.3 0.0 0.00013 21.6 0.0 1.8 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 KXL49705.1 - 6.6e-05 23.0 0.0 0.00019 21.5 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 KXL49705.1 - 0.00015 22.1 0.1 0.00033 21.0 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KXL49705.1 - 0.00016 21.5 0.0 0.00045 20.1 0.0 1.7 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_II PF14492.6 KXL49705.1 - 0.00024 21.1 0.0 0.00059 19.9 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.10 KXL49705.1 - 0.0043 16.5 0.0 0.011 15.2 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 KXL49705.1 - 0.015 15.3 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Snurportin1 PF11538.8 KXL49705.1 - 0.13 12.5 2.5 0.26 11.5 2.5 1.5 1 0 0 1 1 1 0 Snurportin1 Glyco_trans_2_3 PF13632.6 KXL49706.1 - 8.6e-50 169.4 1.7 8.6e-50 169.4 1.7 2.4 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KXL49706.1 - 6.1e-06 26.2 0.0 4.1e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KXL49706.1 - 0.00026 21.0 0.1 0.00047 20.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KXL49706.1 - 0.092 12.2 0.1 0.21 11.0 0.0 1.5 2 0 0 2 2 2 0 Glycosyl transferase family 21 E1-E2_ATPase PF00122.20 KXL49706.1 - 7.2 6.1 5.6 7.8 6.0 0.1 2.5 2 0 0 2 2 2 0 E1-E2 ATPase OTU PF02338.19 KXL49707.1 - 7.6e-23 81.4 0.0 1.7e-22 80.3 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KXL49707.1 - 0.00043 19.8 0.0 0.26 10.7 0.0 2.5 1 1 1 2 2 2 2 Peptidase C65 Otubain MBF1 PF08523.10 KXL49708.1 - 4.7e-25 87.8 2.6 4.7e-25 87.8 2.6 1.9 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 KXL49708.1 - 0.0022 18.0 0.0 0.0072 16.4 0.0 1.9 2 1 0 2 2 2 1 Helix-turn-helix HTH_31 PF13560.6 KXL49708.1 - 0.019 15.3 0.1 0.082 13.3 0.0 2.0 2 1 0 2 2 2 0 Helix-turn-helix domain ANAPC4_WD40 PF12894.7 KXL49709.1 - 0.00025 21.3 4.3 0.51 10.7 0.1 4.9 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXL49709.1 - 0.0026 18.5 13.5 0.17 12.8 0.4 5.2 7 0 0 7 7 7 2 WD domain, G-beta repeat DUF4325 PF14213.6 KXL49709.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 STAS-like domain of unknown function (DUF4325) DUF2235 PF09994.9 KXL49710.1 - 2.5e-70 237.1 0.0 3.7e-70 236.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2800 PF10926.8 KXL49710.1 - 0.042 13.1 0.0 0.064 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2800) Pkinase PF00069.25 KXL49711.1 - 9.5e-15 54.7 0.0 1.3e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL49711.1 - 4.5e-07 29.4 0.0 6.3e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kri1_C PF12936.7 KXL49712.1 - 6.7e-30 103.1 0.0 6.7e-30 103.1 0.0 4.3 5 0 0 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.12 KXL49712.1 - 2.2e-22 79.6 1.5 2.2e-22 79.6 1.5 5.4 4 1 0 4 4 4 1 KRI1-like family DEAD PF00270.29 KXL49713.1 - 1.3e-36 126.0 0.0 3.6e-36 124.6 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXL49713.1 - 1.3e-22 80.3 0.0 2.1e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL49713.1 - 0.043 13.8 0.0 0.069 13.2 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KXL49713.1 - 0.22 10.8 0.0 0.49 9.6 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Ribosomal_L7Ae PF01248.26 KXL49716.1 - 1.7e-26 91.7 1.1 2.3e-26 91.4 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 KXL49716.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 PELOTA RNA binding domain ZapB PF06005.12 KXL49717.1 - 0.053 14.0 0.2 0.11 13.0 0.2 1.4 1 0 0 1 1 1 0 Cell division protein ZapB Glyco_hydro_11 PF00457.17 KXL49718.1 - 4.9e-61 205.4 15.8 5.7e-61 205.2 15.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Sugar_tr PF00083.24 KXL49719.1 - 1.9e-100 336.9 33.2 2.2e-100 336.7 33.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL49719.1 - 2.5e-27 95.7 32.4 2.5e-27 95.7 32.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily VQ PF05678.14 KXL49719.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 VQ motif YozE_SAM_like PF06855.12 KXL49720.1 - 0.11 12.7 0.0 0.31 11.2 0.0 1.8 1 0 0 1 1 1 0 YozE SAM-like fold HMGL-like PF00682.19 KXL49721.1 - 5.3e-43 147.5 0.0 4.3e-31 108.4 0.0 2.0 2 0 0 2 2 2 2 HMGL-like Retinal PF15449.6 KXL49721.1 - 0.036 11.9 4.5 0.048 11.4 4.5 1.2 1 0 0 1 1 1 0 Retinal protein Beta-lactamase PF00144.24 KXL49722.1 - 3.2e-45 154.8 0.1 9.2e-45 153.3 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase Sec6 PF06046.13 KXL49723.1 - 5.8e-151 503.7 8.0 7.1e-151 503.4 8.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec6 Integrin_beta PF00362.18 KXL49723.1 - 0.13 11.9 0.5 0.32 10.6 0.0 1.9 2 0 0 2 2 2 0 Integrin beta chain VWA domain SRP1_TIP1 PF00660.17 KXL49723.1 - 0.13 12.4 0.2 0.81 9.8 0.2 2.3 2 0 0 2 2 2 0 Seripauperin and TIP1 family Vps53_N PF04100.12 KXL49723.1 - 0.63 9.0 12.3 0.17 10.8 1.2 3.5 3 1 1 4 4 4 0 Vps53-like, N-terminal Ribosomal_L30 PF00327.20 KXL49724.1 - 4.1e-16 58.6 0.1 5.8e-16 58.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Arrestin_N PF00339.29 KXL49725.1 - 1.1e-08 35.3 0.1 4.3e-08 33.3 0.1 1.9 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Gpr1_Fun34_YaaH PF01184.19 KXL49726.1 - 5.3e-38 130.7 22.0 6.6e-38 130.4 22.0 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2244 PF10003.9 KXL49726.1 - 0.47 10.1 4.7 1.5 8.5 4.7 1.8 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) DUF2353 PF09789.9 KXL49727.1 - 0.00099 18.6 13.4 0.00099 18.6 13.4 1.7 2 0 0 2 2 2 1 Uncharacterized coiled-coil protein (DUF2353) BicD PF09730.9 KXL49727.1 - 0.001 17.6 20.0 0.0019 16.7 20.0 1.4 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D Tektin PF03148.14 KXL49727.1 - 0.0026 16.6 8.4 0.0026 16.6 8.4 2.6 1 1 1 2 2 2 1 Tektin family SHE3 PF17078.5 KXL49727.1 - 0.0087 15.8 12.6 0.018 14.8 12.6 1.5 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 DUF1664 PF07889.12 KXL49727.1 - 0.014 15.4 9.7 0.3 11.1 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PC4 PF02229.16 KXL49727.1 - 0.015 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Transcriptional Coactivator p15 (PC4) TPR_MLP1_2 PF07926.12 KXL49727.1 - 0.017 15.2 24.8 0.017 15.2 24.8 3.6 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein ADIP PF11559.8 KXL49727.1 - 0.019 15.0 30.9 0.028 14.5 14.5 2.6 2 1 1 3 3 2 0 Afadin- and alpha -actinin-Binding DUF4179 PF13786.6 KXL49727.1 - 0.023 15.1 0.0 0.12 12.8 0.0 2.2 2 1 0 2 2 1 0 Domain of unknown function (DUF4179) EzrA PF06160.12 KXL49727.1 - 0.14 10.4 20.1 0.16 10.2 6.8 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Bacillus_HBL PF05791.11 KXL49727.1 - 0.19 11.5 12.1 0.64 9.8 3.6 2.5 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) CENP-F_leu_zip PF10473.9 KXL49727.1 - 0.21 11.6 32.2 0.17 11.9 11.7 2.8 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 KXL49727.1 - 0.37 10.3 23.9 0.2 11.2 17.4 2.4 1 1 1 2 2 2 0 Intermediate filament protein GAS PF13851.6 KXL49727.1 - 0.52 9.6 29.9 0.045 13.1 23.6 2.4 2 2 0 2 2 2 0 Growth-arrest specific micro-tubule binding SlyX PF04102.12 KXL49727.1 - 0.61 10.7 19.5 1.7 9.3 1.3 3.6 2 1 1 3 3 3 0 SlyX TssO PF17561.2 KXL49727.1 - 0.8 9.8 3.8 1.9 8.6 3.9 1.7 1 1 0 1 1 1 0 Type VI secretion system, TssO DUF4763 PF15960.5 KXL49727.1 - 0.88 8.8 17.7 0.13 11.5 3.2 3.2 1 1 1 3 3 3 0 Domain of unknown function (DUF4763) Yuri_gagarin PF15934.5 KXL49727.1 - 1.2 9.0 15.5 0.062 13.1 4.8 2.1 1 1 1 2 2 2 0 Yuri gagarin Cep57_CLD_2 PF14197.6 KXL49727.1 - 2 8.6 27.1 3.8 7.7 8.6 3.9 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 DUF4201 PF13870.6 KXL49727.1 - 2 8.1 19.5 6.2 6.5 4.8 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Spc7 PF08317.11 KXL49727.1 - 2.2 7.1 38.1 0.056 12.3 16.4 2.6 2 1 1 3 3 3 0 Spc7 kinetochore protein Bap31_Bap29_C PF18035.1 KXL49727.1 - 2.3 8.3 19.1 2.2 8.4 7.1 4.2 3 1 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain Fez1 PF06818.15 KXL49727.1 - 2.3 8.6 29.8 34 4.8 29.8 2.4 1 1 0 1 1 1 0 Fez1 DUF4407 PF14362.6 KXL49727.1 - 2.4 7.4 31.1 0.15 11.4 22.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Prominin PF05478.11 KXL49727.1 - 2.6 5.9 7.8 4.4 5.1 7.8 1.3 1 0 0 1 1 1 0 Prominin Metal_resist PF13801.6 KXL49727.1 - 4.1 7.6 20.0 0.62 10.3 9.0 2.4 1 1 0 2 2 2 0 Heavy-metal resistance TEX13 PF15186.6 KXL49727.1 - 4.6 6.9 20.2 5 6.8 7.7 2.4 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family Lectin_N PF03954.14 KXL49727.1 - 5.1 6.9 18.6 1.6 8.4 2.8 3.4 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain HrpB7 PF09486.10 KXL49727.1 - 6 7.2 29.6 3.1 8.2 15.5 2.8 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Exonuc_VII_L PF02601.15 KXL49727.1 - 6.4 6.3 19.3 0.98 8.9 15.6 1.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit Fungal_TACC PF12709.7 KXL49727.1 - 6.6 7.3 17.6 3 8.3 5.5 3.6 2 1 2 4 4 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins CHASE3 PF05227.13 KXL49727.1 - 7.8 6.4 22.7 0.21 11.5 10.5 2.9 2 1 1 3 3 3 0 CHASE3 domain APG6_N PF17675.1 KXL49727.1 - 8 7.0 45.9 0.48 11.0 19.9 3.4 2 2 1 3 3 2 0 Apg6 coiled-coil region FUSC PF04632.12 KXL49727.1 - 8.1 4.8 17.3 21 3.5 17.3 1.7 1 1 0 1 1 1 0 Fusaric acid resistance protein family Golgin_A5 PF09787.9 KXL49727.1 - 9.5 5.6 29.7 0.16 11.4 9.5 2.5 2 1 1 3 3 3 0 Golgin subfamily A member 5 She9_MDM33 PF05546.11 KXL49727.1 - 9.7 5.9 16.4 2.3 8.0 7.3 2.4 1 1 1 2 2 2 0 She9 / Mdm33 family AFG1_ATPase PF03969.16 KXL49728.1 - 2.8e-96 322.6 0.0 4.2e-92 308.8 0.0 2.3 2 0 0 2 2 2 2 AFG1-like ATPase AAA_14 PF13173.6 KXL49728.1 - 0.00017 21.7 0.0 0.00035 20.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXL49728.1 - 0.0005 20.5 0.3 1.4 9.3 0.0 3.3 3 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 KXL49728.1 - 0.0049 17.1 0.2 0.04 14.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain Bac_DnaA PF00308.18 KXL49728.1 - 0.012 15.5 0.2 1.9 8.3 0.2 2.7 2 1 0 2 2 2 0 Bacterial dnaA protein NACHT PF05729.12 KXL49728.1 - 0.037 13.9 0.0 0.21 11.5 0.0 2.1 1 1 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 KXL49728.1 - 0.039 14.4 0.1 0.19 12.1 0.0 2.2 2 1 0 2 2 2 0 RNA helicase TsaE PF02367.17 KXL49728.1 - 0.088 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 KXL49728.1 - 0.11 13.0 0.0 0.38 11.2 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) EspB_PE PF18625.1 KXL49728.1 - 0.13 12.7 0.0 4.1 7.9 0.0 2.5 2 0 0 2 2 2 0 ESX-1 secreted protein B PE domain HNOB PF07700.15 KXL49728.1 - 0.24 11.3 2.4 0.88 9.5 0.1 2.5 2 0 0 2 2 2 0 Haem-NO-binding zf-RING_2 PF13639.6 KXL49729.1 - 6.4e-11 42.4 12.1 9.8e-11 41.8 12.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KXL49729.1 - 2.4e-09 37.4 7.6 4.3e-09 36.5 7.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KXL49729.1 - 2.6e-06 27.2 11.4 4.2e-06 26.5 11.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXL49729.1 - 5.5e-06 26.2 10.7 8.4e-06 25.6 10.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KXL49729.1 - 1.8e-05 24.3 7.8 2.9e-05 23.6 7.8 1.2 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KXL49729.1 - 3.6e-05 23.4 10.2 6.5e-05 22.6 10.2 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KXL49729.1 - 0.00028 20.8 8.3 0.00057 19.9 8.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXL49729.1 - 0.0012 18.8 9.8 0.0018 18.2 9.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KXL49729.1 - 0.0013 18.7 4.7 0.0025 17.8 4.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KXL49729.1 - 0.0089 15.9 8.7 0.016 15.1 8.7 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KXL49729.1 - 0.013 15.3 8.6 0.021 14.7 8.6 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 KXL49729.1 - 1 9.2 4.2 1.9 8.4 4.2 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 KXL49729.1 - 1.3 9.3 7.0 2.5 8.3 7.0 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 KXL49729.1 - 1.4 9.1 11.7 2.3 8.4 11.7 1.4 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 KXL49729.1 - 3.9 7.3 10.0 33 4.4 10.0 2.1 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 KXL49729.1 - 5.2 7.5 9.7 11 6.5 9.7 1.5 1 1 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.6 KXL49729.1 - 5.6 7.2 8.2 0.083 13.1 1.2 1.6 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING RNA_pol_I_TF PF04090.12 KXL49730.1 - 4.9e-15 55.6 0.1 2e-14 53.6 0.1 1.8 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor TPR_6 PF13174.6 KXL49730.1 - 0.049 14.3 0.3 0.81 10.5 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat PLN_propep PF16485.5 KXL49730.1 - 0.08 12.7 0.1 9.3 6.1 0.0 2.8 2 0 0 2 2 2 0 Protealysin propeptide CMD PF02627.20 KXL49731.1 - 1.1e-23 83.1 0.0 3.4e-12 46.2 0.0 2.3 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family MobL PF18555.1 KXL49731.1 - 0.13 11.5 0.1 12 5.0 0.0 2.1 2 0 0 2 2 2 0 MobL relaxases zf-AN1 PF01428.16 KXL49733.1 - 5.2e-25 87.3 24.2 5.9e-13 48.7 8.7 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.21 KXL49733.1 - 0.00051 20.2 15.7 0.0062 16.7 4.7 2.4 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain zf-C5HC2 PF02928.16 KXL49733.1 - 0.047 14.1 1.3 0.047 14.1 1.3 2.8 2 1 1 3 3 3 0 C5HC2 zinc finger Transp_Tc5_C PF04236.15 KXL49733.1 - 0.087 13.2 11.7 0.27 11.6 2.3 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain C1_4 PF07975.12 KXL49733.1 - 5.9 7.2 18.6 2.7 8.3 7.3 3.0 2 1 0 2 2 2 0 TFIIH C1-like domain Na_Ca_ex PF01699.24 KXL49735.1 - 2.7e-31 108.5 26.3 1.4e-15 57.6 9.4 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF2157 PF09925.9 KXL49735.1 - 1.1 9.0 9.3 5.6 6.8 1.0 3.5 2 1 2 4 4 4 0 Predicted membrane protein (DUF2157) UPF0220 PF05255.11 KXL49735.1 - 7.1 6.1 9.2 20 4.7 4.4 2.9 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0220) Peptidase_M28 PF04389.17 KXL49736.1 - 4.5e-32 111.3 0.0 6.3e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KXL49736.1 - 1.2e-07 31.6 0.1 2.3e-07 30.8 0.1 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 KXL49736.1 - 0.12 11.8 0.4 0.68 9.3 0.0 2.2 3 0 0 3 3 3 0 Nicastrin Aconitase PF00330.20 KXL49737.1 - 5.6e-163 543.2 0.0 6.9e-163 542.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KXL49737.1 - 3.4e-41 140.6 0.0 6.8e-41 139.7 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain R3H-assoc PF13902.6 KXL49738.1 - 3.1e-24 85.9 7.8 6.6e-24 84.8 7.8 1.6 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.22 KXL49738.1 - 0.0093 15.9 1.4 0.14 12.1 0.1 2.6 2 0 0 2 2 2 1 R3H domain Gpr1_Fun34_YaaH PF01184.19 KXL49739.1 - 3.7e-32 111.6 18.2 4.5e-32 111.3 18.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family MFS_1 PF07690.16 KXL49740.1 - 1.3e-46 159.2 39.8 1.7e-40 139.1 26.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXL49740.1 - 0.00016 20.1 4.5 0.00045 18.6 0.9 2.7 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 KXL49740.1 - 0.5 8.9 32.7 9.6 4.6 0.5 3.6 2 2 1 3 3 3 0 MFS/sugar transport protein Otopetrin PF03189.13 KXL49741.1 - 0.05 12.4 2.7 0.048 12.5 2.7 1.1 1 0 0 1 1 1 0 Otopetrin DUF4834 PF16118.5 KXL49741.1 - 0.07 14.1 1.5 0.11 13.4 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) OrfB_Zn_ribbon PF07282.11 KXL49741.1 - 0.15 12.0 0.2 0.15 12.0 0.2 2.0 1 1 1 2 2 2 0 Putative transposase DNA-binding domain SOG2 PF10428.9 KXL49741.1 - 0.32 10.2 16.7 0.34 10.1 16.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Apt1 PF10351.9 KXL49741.1 - 0.38 9.6 4.9 0.38 9.6 4.9 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain FSA_C PF10479.9 KXL49741.1 - 0.69 8.0 18.4 0.83 7.7 18.4 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Shisa PF13908.6 KXL49741.1 - 2 8.6 15.0 3.3 7.9 15.0 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Dicty_REP PF05086.12 KXL49741.1 - 5.1 4.9 10.4 6.3 4.6 10.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pex14_N PF04695.13 KXL49741.1 - 5.8 7.5 13.6 1.7 9.2 10.5 1.6 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region INO80_Ies4 PF08193.11 KXL49743.1 - 8.2e-59 199.5 20.1 9.9e-59 199.2 20.1 1.0 1 0 0 1 1 1 1 INO80 complex subunit Ies4 CLTH PF10607.9 KXL49744.1 - 4.5e-26 91.5 0.0 1.3e-25 90.0 0.0 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 KXL49744.1 - 2.6e-23 82.4 0.1 4.7e-23 81.6 0.1 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 KXL49744.1 - 0.0002 21.2 0.1 0.0006 19.7 0.1 1.8 1 0 0 1 1 1 1 LisH SGT1 PF07093.11 KXL49745.1 - 0.6 8.5 10.0 1.4 7.3 10.0 1.5 1 0 0 1 1 1 0 SGT1 protein RPA43_OB PF17875.1 KXL49746.1 - 3e-23 82.8 0.2 3e-23 82.8 0.2 4.0 2 2 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 KXL49746.1 - 1.1e-05 25.7 0.0 2.5e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 NLRC4_HD2 PF17776.1 KXL49746.1 - 0.22 12.1 0.1 0.22 12.1 0.1 2.1 2 1 0 2 2 2 0 NLRC4 helical domain HD2 DnaJ PF00226.31 KXL49747.1 - 8.8e-11 41.8 0.1 1.6e-10 40.9 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain VARLMGL PF14383.6 KXL49747.1 - 0.036 13.6 0.1 0.066 12.8 0.1 1.4 1 0 0 1 1 1 0 DUF761-associated sequence motif DUF1492 PF07374.11 KXL49747.1 - 0.08 13.1 0.0 0.23 11.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1492) RRP7 PF12923.7 KXL49748.1 - 3.4e-30 104.6 14.0 3.4e-30 104.6 14.0 1.6 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 KXL49748.1 - 2e-25 89.5 0.0 3.9e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRM_1 PF00076.22 KXL49748.1 - 0.00054 19.7 0.0 0.27 11.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KXL49748.1 - 0.85 9.7 9.1 4.6 7.4 9.2 2.0 2 0 0 2 2 2 0 RNA binding motif Rad51 PF08423.11 KXL49749.1 - 2.2e-102 341.7 0.0 2.7e-102 341.4 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KXL49749.1 - 6.6e-08 32.3 0.0 1.1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 KXL49749.1 - 1.4e-07 32.0 1.0 4.9e-07 30.3 0.2 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 KXL49749.1 - 2.8e-06 26.8 0.0 7.6e-06 25.4 0.0 1.8 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 KXL49749.1 - 0.0049 16.5 0.0 0.0072 15.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain RNA_pol_A_CTD PF03118.15 KXL49749.1 - 0.0066 16.2 0.7 0.016 14.9 0.7 1.7 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain HRDC PF00570.23 KXL49749.1 - 0.047 13.7 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 HRDC domain Ribosomal_L27_C PF18471.1 KXL49749.1 - 0.18 11.2 1.0 13 5.1 0.3 2.3 2 0 0 2 2 2 0 Ribosomal L27 protein C-terminal domain zf-CCHC PF00098.23 KXL49750.1 - 2.6e-32 109.5 32.7 4.8e-08 32.7 2.7 5.4 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.6 KXL49750.1 - 5.9e-09 35.7 12.1 0.021 14.8 0.0 4.8 3 1 1 4 4 4 4 Zinc knuckle zf-CCHC_5 PF14787.6 KXL49750.1 - 3.4e-06 26.6 22.7 0.021 14.5 0.9 4.7 4 1 1 5 5 5 4 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 KXL49750.1 - 9.7e-05 22.0 21.8 0.21 11.4 0.9 5.1 5 0 0 5 5 5 3 Zinc knuckle zf-CCHC_6 PF15288.6 KXL49750.1 - 3.6 7.5 28.5 0.34 10.8 1.3 4.5 4 1 1 5 5 5 0 Zinc knuckle UDPGP PF01704.18 KXL49751.1 - 2.1e-56 191.4 0.0 2.8e-56 191.0 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Fer4_20 PF14691.6 KXL49751.1 - 0.13 12.1 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Arrestin_N PF00339.29 KXL49752.1 - 7.7e-10 39.0 0.0 1.6e-08 34.7 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Bul1_N PF04425.12 KXL49752.1 - 2.4e-08 33.2 0.0 7.5e-05 21.7 0.0 2.4 2 0 0 2 2 2 2 Bul1 N terminus Bul1_C PF04426.12 KXL49752.1 - 1.4e-05 24.6 0.0 2.2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Bul1 C terminus ABC_tran PF00005.27 KXL49753.1 - 7.1e-40 136.7 0.0 4.2e-19 69.4 0.0 3.6 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KXL49753.1 - 2.6e-16 60.3 5.2 0.0008 19.3 0.2 4.4 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXL49753.1 - 5e-16 58.8 0.0 3e-06 26.9 0.2 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 KXL49753.1 - 2e-08 34.2 2.2 6.2e-08 32.6 2.2 1.9 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 KXL49753.1 - 2.2e-08 33.7 0.1 0.00098 18.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 KXL49753.1 - 2e-05 24.4 1.1 0.49 10.1 0.0 3.4 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KXL49753.1 - 2.4e-05 24.4 0.1 0.36 10.9 0.0 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 KXL49753.1 - 3.1e-05 24.6 0.0 0.065 13.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 KXL49753.1 - 0.00023 21.1 0.2 0.012 15.5 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KXL49753.1 - 0.00035 21.0 4.0 0.3 11.4 0.5 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KXL49753.1 - 0.00051 20.3 1.5 0.029 14.6 0.0 3.3 3 1 0 3 3 2 1 AAA domain AAA_15 PF13175.6 KXL49753.1 - 0.00062 19.6 1.5 0.06 13.1 0.0 3.0 4 0 0 4 4 3 1 AAA ATPase domain NACHT PF05729.12 KXL49753.1 - 0.0013 18.7 0.2 0.21 11.5 0.0 2.9 3 0 0 3 3 3 1 NACHT domain DUF87 PF01935.17 KXL49753.1 - 0.0021 18.2 0.3 3.2 7.8 0.1 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_25 PF13481.6 KXL49753.1 - 0.0035 16.9 0.7 0.25 10.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 KXL49753.1 - 0.0048 16.4 0.0 0.088 12.3 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region MeaB PF03308.16 KXL49753.1 - 0.0057 15.7 0.2 0.9 8.5 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 KXL49753.1 - 0.013 15.4 0.1 3.7 7.4 0.1 3.4 3 0 0 3 3 3 0 NTPase NB-ARC PF00931.22 KXL49753.1 - 0.017 14.4 2.0 2.3 7.3 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain FtsK_SpoIIIE PF01580.18 KXL49753.1 - 0.026 13.9 0.1 3.2 7.0 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_18 PF13238.6 KXL49753.1 - 0.028 14.9 0.2 11 6.6 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.6 KXL49753.1 - 0.031 14.4 5.9 1.9 8.7 0.0 3.5 3 1 0 3 3 3 0 AAA domain AAA PF00004.29 KXL49753.1 - 0.04 14.3 0.0 5.6 7.4 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KXL49753.1 - 0.04 13.9 0.0 2.3 8.2 0.0 3.0 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 KXL49753.1 - 0.053 13.9 0.0 1.8 9.0 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 KXL49753.1 - 0.065 12.9 0.7 2.7 7.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 KXL49753.1 - 0.072 13.3 0.2 4.8 7.4 0.1 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 KXL49753.1 - 0.074 13.1 0.4 1.5 8.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KXL49753.1 - 0.086 13.1 0.0 1.2 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.18 KXL49753.1 - 0.17 11.3 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF2237 PF09996.9 KXL49754.1 - 5.3e-42 142.4 0.0 6.1e-42 142.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) DUF3748 PF12566.8 KXL49755.1 - 0.0049 16.8 0.2 0.041 13.8 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3748) Helo_like_N PF17111.5 KXL49755.1 - 0.12 11.7 1.1 5.5 6.3 0.0 2.9 3 0 0 3 3 3 0 Fungal N-terminal domain of STAND proteins Fer4_13 PF13370.6 KXL49755.1 - 2.2 8.9 4.6 7.5 7.2 0.0 3.6 3 2 2 5 5 5 0 4Fe-4S single cluster domain of Ferredoxin I Ras PF00071.22 KXL49757.1 - 2.3e-44 150.9 0.0 2.9e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXL49757.1 - 6.6e-31 107.0 0.0 1.1e-30 106.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXL49757.1 - 4.1e-13 49.2 0.0 8.8e-12 44.8 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXL49757.1 - 1e-06 28.5 0.0 2.1e-06 27.4 0.0 1.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KXL49757.1 - 5.2e-05 22.7 0.0 7.2e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXL49757.1 - 5.5e-05 23.2 0.0 9.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KXL49757.1 - 0.0011 19.4 0.1 0.0038 17.6 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain SRPRB PF09439.10 KXL49757.1 - 0.0023 17.4 0.0 0.0033 16.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KXL49757.1 - 0.0039 17.1 0.0 0.089 12.7 0.0 2.4 1 1 0 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 KXL49757.1 - 0.0067 16.2 0.1 0.54 10.0 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 KXL49757.1 - 0.01 16.3 0.0 0.024 15.1 0.0 1.7 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.12 KXL49757.1 - 0.015 15.2 0.2 0.071 13.0 0.1 2.0 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 KXL49757.1 - 0.018 15.2 0.0 0.03 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KXL49757.1 - 0.07 13.4 0.6 0.27 11.5 0.2 2.1 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KXL49757.1 - 0.086 12.8 0.1 0.27 11.2 0.1 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Tropomodulin PF03250.14 KXL49757.1 - 0.21 11.6 0.0 0.33 11.0 0.0 1.2 1 0 0 1 1 1 0 Tropomodulin PAF-AH_p_II PF03403.13 KXL49758.1 - 1.7e-43 148.6 0.0 2.1e-42 145.0 0.0 2.2 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KXL49758.1 - 0.00032 19.7 0.0 0.0014 17.6 0.0 1.9 2 0 0 2 2 2 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KXL49758.1 - 0.0015 17.9 0.0 0.044 13.1 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KXL49758.1 - 0.01 14.9 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase TFIIA PF03153.13 KXL49759.1 - 4.5e-10 40.1 0.1 5.3e-10 39.9 0.1 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Arrestin_N PF00339.29 KXL49760.1 - 1.7e-11 44.4 0.1 2.5e-10 40.6 0.0 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.12 KXL49760.1 - 0.012 15.1 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Bul1 C terminus Clr5 PF14420.6 KXL49761.1 - 6e-13 48.8 0.3 2.9e-12 46.6 0.2 2.3 2 0 0 2 2 2 1 Clr5 domain THB PF18362.1 KXL49761.1 - 0.14 11.8 0.1 0.28 10.8 0.1 1.5 1 0 0 1 1 1 0 Tri-helix bundle domain Fungal_trans PF04082.18 KXL49762.1 - 5e-17 61.8 0.1 7e-17 61.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL49762.1 - 8.8e-09 35.3 10.4 1.5e-08 34.6 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1128 PF06569.11 KXL49762.1 - 0.024 14.6 0.0 0.068 13.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) HATPase_c PF02518.26 KXL49763.1 - 1.7e-23 83.3 0.0 3.5e-23 82.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXL49763.1 - 7.4e-23 80.9 0.0 1.5e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KXL49763.1 - 4.4e-08 33.0 1.9 7.5e-07 29.1 0.1 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 KXL49763.1 - 8.5e-08 32.4 0.0 1.5e-05 25.2 0.0 2.7 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 KXL49763.1 - 1.2e-06 28.7 0.0 2.3e-05 24.6 0.0 2.7 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 KXL49763.1 - 2.6e-06 27.4 0.0 0.00092 19.2 0.0 2.9 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 KXL49763.1 - 0.00022 21.1 0.0 0.00059 19.8 0.0 1.7 1 0 0 1 1 1 1 PAS domain GAF_2 PF13185.6 KXL49763.1 - 0.00097 19.4 0.0 0.0052 17.1 0.0 2.3 2 0 0 2 2 2 1 GAF domain PAS_3 PF08447.12 KXL49763.1 - 0.0036 17.5 0.0 0.009 16.3 0.0 1.7 1 0 0 1 1 1 1 PAS fold GAF_3 PF13492.6 KXL49763.1 - 0.019 15.3 0.0 0.042 14.2 0.0 1.6 1 0 0 1 1 1 0 GAF domain GAF PF01590.26 KXL49763.1 - 0.09 13.4 0.0 0.35 11.5 0.0 2.0 1 0 0 1 1 1 0 GAF domain Methyltransf_23 PF13489.6 KXL49764.1 - 4.8e-18 65.5 0.0 6.5e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL49764.1 - 4.7e-08 33.6 0.0 0.0049 17.5 0.0 2.5 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KXL49764.1 - 5e-08 33.5 0.0 0.0042 17.7 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KXL49764.1 - 0.00013 22.6 0.0 0.013 16.2 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL49764.1 - 0.00072 19.4 0.0 0.13 12.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXL49764.1 - 0.013 14.8 0.0 0.24 10.7 0.0 2.1 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KXL49764.1 - 0.2 11.1 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_23 PF13489.6 KXL49765.1 - 2e-13 50.5 0.0 2.9e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXL49765.1 - 4.4e-05 23.0 0.0 7.6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 KXL49765.1 - 8.8e-05 23.1 0.0 0.00023 21.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL49765.1 - 0.00021 21.1 0.0 0.00042 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KXL49765.1 - 0.0017 18.5 0.0 0.0034 17.5 0.0 1.5 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_12 PF08242.12 KXL49765.1 - 0.0047 17.6 0.0 0.0096 16.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KXL49765.1 - 0.0054 16.7 0.0 0.016 15.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KXL49765.1 - 0.019 14.5 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.20 KXL49765.1 - 0.024 13.9 0.0 0.033 13.5 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 KXL49765.1 - 0.18 12.5 0.0 0.34 11.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain FAD-oxidase_C PF02913.19 KXL49766.1 - 8.8e-59 199.1 0.0 1.5e-58 198.3 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KXL49766.1 - 2.3e-35 121.4 0.0 4.8e-35 120.3 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain GATA PF00320.27 KXL49767.1 - 6.8e-16 57.6 4.9 1.4e-15 56.6 4.9 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 KXL49767.1 - 2.8e-14 53.2 0.0 5.3e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 KXL49767.1 - 1.1e-11 44.8 0.0 2.3e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KXL49767.1 - 1.1e-06 28.9 0.0 2.2e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KXL49767.1 - 3.5e-06 27.2 0.1 1.4e-05 25.2 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS_11 PF14598.6 KXL49767.1 - 0.00021 21.4 0.0 0.00048 20.2 0.0 1.5 1 0 0 1 1 1 1 PAS domain Zn-ribbon_8 PF09723.10 KXL49767.1 - 0.0099 16.0 0.2 0.023 14.8 0.2 1.6 1 0 0 1 1 1 1 Zinc ribbon domain DUF3824 PF12868.7 KXL49767.1 - 0.17 12.6 4.5 0.094 13.4 2.1 1.8 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) DUF4428 PF14471.6 KXL49767.1 - 2.8 7.9 6.6 0.32 10.9 0.9 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) AAA_23 PF13476.6 KXL49768.1 - 1.9e-34 120.0 0.1 1.9e-34 120.0 0.1 8.5 2 1 3 5 5 3 1 AAA domain AAA_21 PF13304.6 KXL49768.1 - 3e-13 50.3 0.0 6.2e-05 22.9 0.0 3.5 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KXL49768.1 - 6.8e-13 49.1 48.0 2.7e-10 40.5 0.7 5.3 1 1 2 3 3 3 2 AAA ATPase domain SMC_N PF02463.19 KXL49768.1 - 1.8e-11 43.9 19.6 1.3e-08 34.6 0.0 3.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KXL49768.1 - 1.4e-06 28.4 0.0 6.2e-06 26.4 0.0 2.2 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.6 KXL49768.1 - 2.3e-05 23.3 19.4 0.0023 16.7 19.3 7.0 3 2 2 6 6 6 3 AAA domain AAA_29 PF13555.6 KXL49768.1 - 3.6e-05 23.4 0.0 7.8e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Laminin_II PF06009.12 KXL49768.1 - 0.0001 22.4 7.1 0.0001 22.4 7.1 8.2 6 2 1 8 8 8 2 Laminin Domain II DUF3800 PF12686.7 KXL49768.1 - 0.00084 20.0 1.6 3.2 8.4 0.6 5.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3800) ABC_tran PF00005.27 KXL49768.1 - 0.044 14.3 0.0 0.044 14.3 0.0 6.5 3 2 0 3 3 1 0 ABC transporter AAA_16 PF13191.6 KXL49768.1 - 0.14 12.5 0.0 0.14 12.5 0.0 5.3 5 1 0 5 5 4 0 AAA ATPase domain Ste5_C PF12194.8 KXL49768.1 - 0.18 11.7 7.7 0.1 12.5 2.0 2.8 2 0 0 2 2 2 0 Protein kinase Fus3-binding Cellulase PF00150.18 KXL49769.1 - 1e-13 51.4 11.5 4.5e-13 49.3 11.5 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CN_hydrolase PF00795.22 KXL49770.1 - 4.2e-58 196.7 0.0 4.7e-58 196.6 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MFS_1 PF07690.16 KXL49772.1 - 4.3e-05 22.6 31.9 8.9e-05 21.6 29.3 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily SNF2_N PF00176.23 KXL49773.1 - 1.9e-61 207.8 0.3 3.3e-61 207.0 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXL49773.1 - 7.2e-15 55.3 0.0 1.8e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL49773.1 - 2e-09 37.7 0.0 6.6e-09 36.0 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.6 KXL49773.1 - 3.1e-08 33.3 1.8 6.2e-08 32.4 1.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXL49773.1 - 2.6e-07 30.4 2.0 2.6e-07 30.4 2.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 KXL49773.1 - 1.1e-05 25.3 0.1 7.1e-05 22.6 0.0 2.3 2 1 0 2 2 2 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.25 KXL49773.1 - 2.7e-05 23.9 4.6 5.9e-05 22.9 4.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXL49773.1 - 0.00052 20.0 3.7 0.0012 18.8 3.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KXL49773.1 - 0.00059 20.1 4.4 0.0014 18.9 4.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KXL49773.1 - 0.00061 19.7 2.5 0.002 18.0 2.6 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KXL49773.1 - 0.014 15.5 6.4 0.041 14.0 6.4 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KXL49773.1 - 0.046 13.6 5.8 0.28 11.1 6.0 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Nop53 PF07767.11 KXL49773.1 - 0.056 12.8 14.3 0.096 12.1 14.3 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) zf-RING_4 PF14570.6 KXL49773.1 - 0.12 12.2 6.5 0.92 9.4 6.7 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.7 KXL49773.1 - 0.23 11.5 4.7 0.61 10.2 4.7 1.7 1 0 0 1 1 1 0 Double zinc ribbon SPT6_acidic PF14632.6 KXL49773.1 - 0.76 10.4 14.1 3.5 8.3 14.1 2.2 1 1 0 1 1 1 0 Acidic N-terminal SPT6 YqfQ PF14181.6 KXL49773.1 - 3 8.0 6.5 5.9 7.0 6.5 1.4 1 0 0 1 1 1 0 YqfQ-like protein CDC45 PF02724.14 KXL49773.1 - 8.1 4.6 13.2 12 4.0 13.2 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2205 PF10224.9 KXL49774.1 - 3.1e-34 116.8 0.3 4.2e-34 116.4 0.3 1.2 1 0 0 1 1 1 1 Short coiled-coil protein Spectrin PF00435.21 KXL49774.1 - 0.033 14.7 0.6 0.051 14.1 0.6 1.2 1 0 0 1 1 1 0 Spectrin repeat Dynactin_p22 PF07426.11 KXL49774.1 - 0.052 13.4 0.2 0.072 12.9 0.2 1.1 1 0 0 1 1 1 0 Dynactin subunit p22 ZapB PF06005.12 KXL49774.1 - 0.055 13.9 0.9 0.093 13.2 0.9 1.3 1 0 0 1 1 1 0 Cell division protein ZapB CCDC106 PF15794.5 KXL49774.1 - 0.069 12.9 1.0 0.13 12.0 0.0 1.8 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 106 YabA PF06156.13 KXL49774.1 - 0.11 13.2 0.1 0.17 12.5 0.1 1.3 1 0 0 1 1 1 0 Initiation control protein YabA LCD1 PF09798.9 KXL49774.1 - 0.15 10.5 0.3 0.19 10.2 0.3 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein Dicer_dimer PF03368.14 KXL49776.1 - 1.2e-05 25.4 0.1 8.6e-05 22.6 0.1 2.2 3 0 0 3 3 3 1 Dicer dimerisation domain dsrm PF00035.26 KXL49776.1 - 0.0017 19.0 0.0 0.078 13.7 0.0 2.4 2 0 0 2 2 2 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KXL49776.1 - 0.0042 17.3 0.0 0.06 13.6 0.0 2.3 2 0 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 LIX1 PF14954.6 KXL49776.1 - 0.042 13.2 0.1 0.079 12.2 0.1 1.4 1 0 0 1 1 1 0 Limb expression 1 TEA PF01285.18 KXL49777.1 - 3.2e-28 97.6 1.4 5.8e-28 96.8 0.4 2.0 2 0 0 2 2 2 1 TEA/ATTS domain RRM_1 PF00076.22 KXL49778.1 - 2.2e-72 238.8 2.9 3.2e-15 55.7 0.0 6.5 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXL49778.1 - 6.3e-10 39.0 0.0 0.025 14.7 0.0 5.3 5 0 0 5 5 5 3 RNA recognition motif RRM_occluded PF16842.5 KXL49778.1 - 1.4e-06 28.1 0.1 1 9.3 0.0 5.6 6 0 0 6 6 6 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KXL49778.1 - 2.7e-05 24.1 0.1 1.7 8.8 0.0 5.5 6 1 0 6 6 6 2 Limkain b1 Smg4_UPF3 PF03467.15 KXL49778.1 - 3.5e-05 23.9 2.4 0.045 13.8 0.0 4.0 4 0 0 4 4 4 2 Smg-4/UPF3 family Nup35_RRM_2 PF14605.6 KXL49778.1 - 0.00092 19.2 0.1 15 5.7 0.0 4.2 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KXL49778.1 - 0.0012 18.4 0.0 5.6 6.6 0.0 3.8 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KXL49778.1 - 0.0017 18.4 7.6 4.8 7.3 0.0 5.7 5 1 2 7 7 7 1 RNA binding motif SET_assoc PF11767.8 KXL49778.1 - 0.012 15.3 0.0 0.72 9.5 0.0 3.3 4 0 0 4 4 4 0 Histone lysine methyltransferase SET associated Dynein_light PF01221.18 KXL49779.1 - 1.7e-39 134.0 2.6 2.2e-39 133.7 2.6 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Spore_YhaL PF14147.6 KXL49779.1 - 2.5 7.9 5.1 18 5.1 5.1 2.2 1 1 0 1 1 1 0 Sporulation protein YhaL zinc_ribbon_15 PF17032.5 KXL49780.1 - 2.9e-05 24.7 0.8 5e-05 24.0 0.8 1.4 1 0 0 1 1 1 1 zinc-ribbon family RecR PF02132.15 KXL49780.1 - 0.15 11.6 2.3 1.1 8.8 0.2 2.2 2 0 0 2 2 2 0 RecR protein zf-LITAF-like PF10601.9 KXL49780.1 - 2.2 8.6 8.2 2.6 8.4 0.2 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HMG_box PF00505.19 KXL49781.1 - 1.9e-13 50.6 2.6 1.9e-13 50.6 2.6 2.1 2 1 0 2 2 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXL49781.1 - 3.1e-08 34.1 1.6 6.2e-08 33.1 1.6 1.5 1 0 0 1 1 1 1 HMG-box domain BUD22 PF09073.10 KXL49781.1 - 0.0046 16.4 13.7 0.0065 15.9 13.7 1.3 1 0 0 1 1 1 1 BUD22 Sporozoite_P67 PF05642.11 KXL49781.1 - 0.0058 14.8 6.5 0.0082 14.3 6.5 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen TFIIA PF03153.13 KXL49781.1 - 0.016 15.2 11.0 0.023 14.7 11.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM176 PF14851.6 KXL49781.1 - 0.019 14.7 3.1 0.039 13.6 3.1 1.5 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.12 KXL49781.1 - 0.024 12.9 9.1 0.03 12.6 9.1 1.2 1 0 0 1 1 1 0 Nop14-like family GCIP PF13324.6 KXL49781.1 - 0.028 14.0 8.5 0.052 13.1 8.5 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting NOA36 PF06524.12 KXL49781.1 - 0.039 13.3 12.5 0.057 12.7 12.5 1.3 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 KXL49781.1 - 0.05 13.2 9.2 0.06 12.9 9.2 1.2 1 0 0 1 1 1 0 PPP4R2 RXT2_N PF08595.11 KXL49781.1 - 0.069 13.2 6.6 0.11 12.5 6.6 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Anillin_N PF16018.5 KXL49781.1 - 0.09 13.4 0.8 0.09 13.4 0.8 2.3 2 2 0 2 2 2 0 Anillin N-terminus TLP-20 PF06088.11 KXL49781.1 - 0.68 9.8 5.6 1.3 8.9 5.6 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) SAPS PF04499.15 KXL49781.1 - 2.1 7.1 4.9 2.4 6.9 4.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Med13_C PF06333.12 KXL49781.1 - 2.8 7.1 6.8 0.59 9.4 2.7 1.8 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain TRAP_alpha PF03896.16 KXL49781.1 - 4.9 6.3 6.2 7.6 5.6 6.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2057 PF09829.9 KXL49781.1 - 5.2 7.2 12.4 2.3 8.4 6.0 2.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) Amidohydro_1 PF01979.20 KXL49782.1 - 1.1e-71 241.9 0.3 1.7e-71 241.3 0.3 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 KXL49782.1 - 9.1e-57 190.6 2.3 2.5e-56 189.2 2.3 1.8 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 KXL49782.1 - 1.6e-41 140.3 0.3 4e-41 139.0 0.3 1.7 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.18 KXL49782.1 - 1.4e-37 127.9 0.0 3.7e-37 126.6 0.0 1.8 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 KXL49782.1 - 2.1e-08 34.1 0.2 0.00039 20.0 0.0 2.9 2 1 0 3 3 3 2 Amidohydrolase family Histidinol_dh PF00815.20 KXL49783.1 - 2.9e-156 520.6 0.9 2.9e-156 520.6 0.9 1.4 2 0 0 2 2 2 1 Histidinol dehydrogenase PRA-CH PF01502.18 KXL49783.1 - 1.9e-24 85.3 0.5 3.9e-24 84.3 0.5 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 KXL49783.1 - 3e-14 53.2 0.0 9.6e-14 51.6 0.0 1.9 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 KXL49783.1 - 0.031 14.5 0.1 0.067 13.4 0.1 1.6 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain Aminotran_5 PF00266.19 KXL49784.1 - 7.3e-55 186.4 0.0 1.1e-54 185.9 0.0 1.2 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KXL49784.1 - 3.1e-05 22.7 0.1 4.6e-05 22.1 0.1 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme ScsC_N PF18312.1 KXL49784.1 - 0.071 12.9 0.0 0.76 9.6 0.0 2.3 2 0 0 2 2 2 0 Copper resistance protein ScsC N-terminal domain WD40 PF00400.32 KXL49785.1 - 1.1e-20 73.5 8.8 1.1e-05 26.1 0.4 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL49785.1 - 0.001 19.4 0.0 0.11 12.8 0.0 3.4 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DPM2 PF07297.12 KXL49786.1 - 6e-28 97.0 2.1 6.8e-28 96.8 2.1 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) COX14 PF14880.6 KXL49786.1 - 0.00018 21.3 1.2 0.00045 20.0 0.0 1.9 2 0 0 2 2 2 1 Cytochrome oxidase c assembly PIG-P PF08510.12 KXL49786.1 - 0.00041 20.3 0.7 0.00043 20.2 0.7 1.1 1 0 0 1 1 1 1 PIG-P LapA_dom PF06305.11 KXL49786.1 - 0.0034 17.2 0.2 0.0034 17.2 0.2 1.6 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain DUF4229 PF14012.6 KXL49786.1 - 0.0036 17.4 2.1 0.0066 16.5 2.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4229) Cytochrom_C_asm PF01578.20 KXL49786.1 - 0.0048 16.7 0.2 0.0048 16.7 0.2 1.0 1 0 0 1 1 1 1 Cytochrome C assembly protein Arf PF00025.21 KXL49787.1 - 1.1e-64 217.1 0.0 1.2e-64 216.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KXL49787.1 - 3.7e-11 42.8 0.0 1.8e-07 30.7 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KXL49787.1 - 1.7e-08 34.1 0.0 2.2e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KXL49787.1 - 1.6e-07 31.5 0.0 5.7e-07 29.8 0.0 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KXL49787.1 - 9.8e-07 28.9 0.0 1.3e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KXL49787.1 - 1.4e-06 28.0 0.0 1.9e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KXL49787.1 - 0.00069 19.0 0.0 0.00077 18.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KXL49787.1 - 0.17 11.4 0.0 6.5 6.2 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain mRNA_decap_C PF16741.5 KXL49787.1 - 0.25 10.7 0.6 0.65 9.3 0.1 1.9 3 0 0 3 3 3 0 mRNA-decapping enzyme C-terminus zf-RING_2 PF13639.6 KXL49789.1 - 3.4e-13 49.7 7.9 3.4e-13 49.7 7.9 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 KXL49789.1 - 1.8e-11 43.6 1.3 3.7e-11 42.6 1.3 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXL49789.1 - 1e-09 38.0 7.5 1e-09 38.0 7.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXL49789.1 - 1.2e-07 31.4 10.1 2e-06 27.5 3.1 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXL49789.1 - 8.6e-07 28.9 3.4 8.6e-07 28.9 3.4 2.7 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXL49789.1 - 3.5e-06 26.8 14.3 7.7e-06 25.7 5.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXL49789.1 - 5e-06 26.4 3.0 5e-06 26.4 3.0 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zinc_ribbon_9 PF14369.6 KXL49789.1 - 8.3e-06 26.0 9.9 0.00028 21.1 4.5 2.6 2 0 0 2 2 2 2 zinc-ribbon zf-rbx1 PF12678.7 KXL49789.1 - 0.00016 21.9 11.2 0.00016 21.9 11.2 2.4 2 1 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KXL49789.1 - 0.00049 19.9 4.7 0.00049 19.9 4.7 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KXL49789.1 - 0.0074 16.4 13.7 0.23 11.7 4.9 2.4 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KXL49789.1 - 0.011 15.5 1.1 0.021 14.6 1.1 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 KXL49789.1 - 0.011 15.8 2.5 0.011 15.8 2.5 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger HypA PF01155.19 KXL49789.1 - 0.012 15.6 5.7 0.03 14.4 0.7 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-UDP PF14569.6 KXL49789.1 - 0.22 11.7 3.7 1.5 9.0 0.4 2.3 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING_4 PF14570.6 KXL49789.1 - 0.75 9.6 13.7 1.8 8.4 4.3 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.7 KXL49789.1 - 1.3 9.1 8.9 1.3 9.1 0.6 2.7 2 1 0 2 2 2 0 Double zinc ribbon zf-C3H2C3 PF17122.5 KXL49789.1 - 1.3 9.1 12.2 0.12 12.4 6.1 2.2 2 0 0 2 2 2 0 Zinc-finger Spt20 PF12090.8 KXL49789.1 - 1.5 8.3 5.6 2.7 7.5 5.6 1.3 1 0 0 1 1 1 0 Spt20 family Zn_ribbon_17 PF17120.5 KXL49789.1 - 2.3 7.9 14.1 0.17 11.5 5.1 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zinc-ribbons_6 PF07191.12 KXL49789.1 - 3.8 7.6 10.6 0.22 11.5 1.2 2.6 2 1 0 2 2 2 0 zinc-ribbons Prok-RING_1 PF14446.6 KXL49789.1 - 3.8 7.5 13.5 8.8 6.3 1.1 3.1 2 2 1 3 3 3 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 KXL49789.1 - 5.5 7.2 10.7 0.87 9.8 5.2 2.6 2 1 0 2 2 2 0 FANCL C-terminal domain PHD PF00628.29 KXL49789.1 - 6.1 6.8 16.3 0.79 9.7 4.6 2.8 2 1 0 2 2 2 0 PHD-finger SARAF PF06682.12 KXL49789.1 - 6.2 6.4 9.7 0.77 9.3 5.5 1.6 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis CAP_N PF01213.19 KXL49790.1 - 1.3e-85 287.6 1.8 1.6e-85 287.4 0.0 1.9 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KXL49790.1 - 6.1e-47 159.1 0.0 8.6e-47 158.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Serinc PF03348.15 KXL49791.1 - 2.9e-156 520.7 3.2 3.3e-156 520.5 3.2 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF2970 PF11174.8 KXL49791.1 - 0.0061 16.4 0.6 0.0061 16.4 0.6 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2970) MFS_1 PF07690.16 KXL49792.1 - 4e-14 52.3 45.5 1.9e-13 50.1 41.8 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 KXL49792.1 - 8.9e-14 51.6 8.8 8.9e-14 51.6 8.8 1.7 2 0 0 2 2 2 1 Nodulin-like MCM PF00493.23 KXL49793.1 - 1.4e-96 321.9 0.1 3.2e-96 320.8 0.1 1.6 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KXL49793.1 - 7e-31 106.7 0.0 1.3e-30 105.9 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KXL49793.1 - 5.9e-24 84.3 0.5 1.2e-23 83.3 0.5 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KXL49793.1 - 4.4e-11 43.3 0.0 1.3e-10 41.8 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KXL49793.1 - 1.5e-06 27.8 0.0 1.7e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KXL49793.1 - 0.004 17.0 0.0 0.0098 15.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXL49793.1 - 0.092 12.7 0.0 0.24 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KXL49793.1 - 0.097 12.4 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain MFS_1 PF07690.16 KXL49794.1 - 5.7e-38 130.8 36.9 5.7e-38 130.8 36.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL49794.1 - 1.4e-07 30.8 11.3 1.4e-07 30.8 11.3 4.0 3 2 1 4 4 4 2 Sugar (and other) transporter Phage_holin_2_3 PF16080.5 KXL49794.1 - 0.016 14.9 1.7 0.16 11.8 0.1 2.9 2 0 0 2 2 2 0 Bacteriophage holin family HP1 HTH_Tnp_Tc5 PF03221.16 KXL49797.1 - 1.6e-13 50.4 0.0 2.8e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KXL49797.1 - 3.2e-06 26.7 0.1 6.2e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain MarR PF01047.22 KXL49797.1 - 0.022 14.7 0.0 0.059 13.3 0.0 1.7 1 0 0 1 1 1 0 MarR family HTH_38 PF13936.6 KXL49797.1 - 0.073 12.8 0.1 0.15 11.8 0.1 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_4 PF13613.6 KXL49797.1 - 0.1 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_Crp_2 PF13545.6 KXL49797.1 - 0.16 11.9 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_23 PF13384.6 KXL49797.1 - 0.2 11.5 0.1 0.61 10.0 0.0 1.8 2 0 0 2 2 2 0 Homeodomain-like domain MRP-L20 PF12824.7 KXL49797.1 - 0.92 9.6 5.3 0.48 10.6 0.1 2.5 2 0 0 2 2 2 0 Mitochondrial ribosomal protein subunit L20 PXA PF02194.15 KXL49798.1 - 1.1e-40 139.6 0.4 2e-40 138.7 0.4 1.4 1 0 0 1 1 1 1 PXA domain Med10 PF09748.9 KXL49799.1 - 6.2e-40 135.9 0.1 7.1e-40 135.7 0.1 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.7 KXL49799.1 - 0.0037 17.1 0.0 0.0045 16.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function, E. rectale Gene description (DUF3877) GCIP PF13324.6 KXL49799.1 - 0.0058 16.3 0.0 0.0078 15.9 0.0 1.2 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting PCIF1_WW PF12237.8 KXL49799.1 - 0.053 13.1 0.0 0.65 9.6 0.0 1.9 2 0 0 2 2 2 0 Phosphorylated CTD interacting factor 1 WW domain SSXT PF05030.12 KXL49799.1 - 0.12 12.0 0.1 0.41 10.3 0.1 1.9 2 0 0 2 2 2 0 SSXT protein (N-terminal region) Aminotran_1_2 PF00155.21 KXL49800.1 - 1.4e-67 228.5 0.0 1.6e-67 228.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KXL49800.1 - 0.00049 19.5 0.0 0.00085 18.7 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KXL49800.1 - 0.0018 17.6 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KXL49800.1 - 0.019 13.9 0.0 0.032 13.2 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KXL49800.1 - 0.05 12.1 0.0 0.09 11.3 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Acyl_transf_1 PF00698.21 KXL49801.1 - 1.7e-43 149.3 0.0 2.5e-43 148.8 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain PP-binding PF00550.25 KXL49801.1 - 3.4e-28 97.8 4.1 1.5e-14 54.1 0.7 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.20 KXL49801.1 - 2.6e-15 57.2 0.8 3.6e-14 53.4 0.0 2.6 3 0 0 3 3 3 1 Thioesterase domain PS-DH PF14765.6 KXL49801.1 - 4.1e-15 55.8 0.0 6.5e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.7 KXL49801.1 - 1.7e-06 28.8 1.0 0.00031 21.4 0.1 2.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family KAsynt_C_assoc PF16197.5 KXL49801.1 - 5.1e-06 26.9 0.0 1.2e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension DUF2974 PF11187.8 KXL49801.1 - 0.039 13.5 0.0 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) SAP130_C PF16014.5 KXL49801.1 - 0.048 12.7 5.9 0.1 11.6 5.9 1.5 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Alginate_lyase PF05426.12 KXL49802.1 - 0.8 9.2 5.9 2.4 7.6 5.9 1.6 1 1 0 1 1 1 0 Alginate lyase SAT PF16073.5 KXL49803.1 - 8e-85 284.4 0.2 1.3e-84 283.7 0.2 1.3 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ketoacyl-synt PF00109.26 KXL49803.1 - 1.8e-78 263.6 0.0 8.3e-78 261.5 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KXL49803.1 - 3.8e-35 120.5 2.1 8.6e-35 119.3 2.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KXL49803.1 - 4.9e-05 22.8 0.1 0.00047 19.6 0.0 2.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain CUE PF02845.16 KXL49804.1 - 4e-11 42.4 0.2 2.2e-10 40.1 0.1 2.2 2 0 0 2 2 2 1 CUE domain DUF3130 PF11328.8 KXL49804.1 - 0.42 10.9 1.4 3.3 8.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3130 MFS_1 PF07690.16 KXL49805.1 - 8.4e-30 103.9 16.3 8.4e-30 103.9 16.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Abhydrolase_9_N PF15420.6 KXL49805.1 - 0.95 9.4 5.9 0.28 11.2 1.0 2.4 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Pkinase PF00069.25 KXL49806.1 - 2.7e-58 197.4 0.0 4.7e-58 196.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL49806.1 - 4.1e-41 141.0 0.0 6.4e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXL49806.1 - 6.7e-09 35.5 0.0 1.5e-06 27.7 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KXL49806.1 - 0.023 14.1 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SAM_3 PF18016.1 KXL49806.1 - 0.032 14.0 0.0 0.096 12.5 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Pkinase_fungal PF17667.1 KXL49806.1 - 0.1 11.4 0.0 0.22 10.3 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase zf-RING_2 PF13639.6 KXL49807.1 - 2e-10 40.8 5.0 3.6e-10 40.0 5.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KXL49807.1 - 1.6e-08 34.3 2.8 2.7e-08 33.5 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXL49807.1 - 6.9e-07 29.0 5.1 1.2e-06 28.2 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXL49807.1 - 9.1e-07 29.1 2.6 2e-06 28.0 2.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KXL49807.1 - 1.3e-06 28.2 4.3 2.3e-06 27.4 4.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXL49807.1 - 6.8e-05 22.6 4.1 0.00013 21.8 4.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KXL49807.1 - 0.00091 19.2 1.7 0.0017 18.3 1.0 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXL49807.1 - 0.0016 18.4 2.6 0.0036 17.2 2.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KXL49807.1 - 0.0066 16.2 1.9 0.015 15.0 1.9 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 KXL49807.1 - 0.017 15.1 1.6 0.032 14.3 1.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KXL49807.1 - 3.6 7.3 5.0 3 7.5 3.0 1.9 2 1 1 3 3 3 0 Zinc-ribbon, C4HC2 type HIT PF01230.23 KXL49808.1 - 7.7e-24 84.3 0.2 1e-23 83.9 0.2 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KXL49808.1 - 3e-14 53.5 0.1 4e-14 53.0 0.1 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KXL49808.1 - 4e-05 23.5 0.0 5.7e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 ATG22 PF11700.8 KXL49809.1 - 2.5e-191 636.5 9.8 2.9e-191 636.3 9.8 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like DUF423 PF04241.15 KXL49809.1 - 0.0007 19.8 0.1 0.0007 19.8 0.1 3.3 3 2 0 4 4 4 1 Protein of unknown function (DUF423) Gpi1 PF05024.15 KXL49810.1 - 2.7e-76 255.8 7.5 5e-76 255.0 7.5 1.5 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) zf-CCCH_4 PF18044.1 KXL49811.1 - 0.0055 16.5 1.4 0.0097 15.7 1.4 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KXL49811.1 - 0.012 15.6 0.8 0.012 15.6 0.8 1.8 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH PF00642.24 KXL49811.1 - 0.05 13.5 0.9 0.11 12.5 0.9 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ribosomal_S10 PF00338.22 KXL49812.1 - 3.2e-26 91.4 0.2 4.1e-26 91.1 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e KH_1 PF00013.29 KXL49813.1 - 7.8e-44 147.4 4.7 1.8e-18 66.1 0.3 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KXL49813.1 - 5.3e-11 42.2 3.4 0.004 16.9 0.2 3.3 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 KXL49813.1 - 4.1e-05 23.5 0.0 0.022 14.8 0.0 2.8 3 0 0 3 3 3 2 KH-like RNA-binding domain KH_4 PF13083.6 KXL49813.1 - 6.5e-05 22.7 0.3 1.4 8.8 0.1 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 KXL49813.1 - 0.00042 20.4 7.2 0.27 11.4 0.2 3.4 3 0 0 3 3 3 2 NusA-like KH domain MFS_1 PF07690.16 KXL49815.1 - 1.6e-15 56.9 34.5 1.6e-15 56.9 34.5 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 KXL49815.1 - 0.0041 15.5 10.6 0.013 13.8 1.2 2.8 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Pardaxin PF07425.11 KXL49815.1 - 4.5 7.0 5.7 0.46 10.1 0.3 2.2 2 0 0 2 2 2 0 Pardaxin Methyltransf_15 PF09445.10 KXL49816.1 - 5.1e-52 175.8 0.0 6.3e-52 175.5 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 KXL49816.1 - 2e-06 27.6 0.0 2.9e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 KXL49816.1 - 2e-05 24.4 0.0 2.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.18 KXL49816.1 - 5.1e-05 23.1 0.0 7.4e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_3 PF01596.17 KXL49816.1 - 0.0076 15.5 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_5 PF01795.19 KXL49816.1 - 0.023 14.2 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 MraW methylase family Methyltransf_25 PF13649.6 KXL49816.1 - 0.13 13.0 0.0 0.24 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KXL49816.1 - 0.17 11.2 0.1 0.25 10.7 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KXL49816.1 - 0.18 11.2 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase BTB PF00651.31 KXL49817.1 - 1.3e-09 38.2 0.0 2.3e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DNA_ligase_A_N PF04675.14 KXL49818.1 - 1e-39 136.6 0.0 1.7e-39 135.9 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.21 KXL49818.1 - 6.9e-22 78.1 0.0 1.2e-21 77.3 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain NuDC PF16273.5 KXL49818.1 - 0.14 12.7 1.6 0.32 11.5 1.6 1.6 1 0 0 1 1 1 0 Nuclear distribution C domain Dopey_N PF04118.14 KXL49819.1 - 8.3e-104 347.0 0.0 8e-103 343.8 0.0 2.7 3 0 0 3 3 3 1 Dopey, N-terminal Mon1 PF03164.14 KXL49820.1 - 5.4e-150 500.0 0.0 6.5e-150 499.7 0.0 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 CH PF00307.31 KXL49821.1 - 1.1e-15 57.8 0.0 2.3e-09 37.4 0.0 2.7 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KXL49821.1 - 0.0064 16.3 0.0 20 5.1 0.0 3.6 3 0 0 3 3 3 2 CAMSAP CH domain IQ PF00612.27 KXL49821.1 - 2.6 8.1 19.4 0.2 11.6 1.6 4.2 4 0 0 4 4 4 0 IQ calmodulin-binding motif DUF155 PF02582.14 KXL49822.1 - 2.2e-52 177.7 0.0 3.8e-52 176.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Cupin_3 PF05899.12 KXL49822.1 - 0.00099 18.8 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Clathrin PF00637.20 KXL49823.1 - 1.4e-14 54.1 0.2 8.1e-14 51.7 0.0 2.1 2 0 0 2 2 2 1 Region in Clathrin and VPS zf-RING_5 PF14634.6 KXL49823.1 - 0.1 12.6 1.3 0.2 11.7 1.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain WD40 PF00400.32 KXL49823.1 - 0.17 12.8 1.5 37 5.4 0.2 4.1 2 1 0 2 2 2 0 WD domain, G-beta repeat WD40_like PF17005.5 KXL49823.1 - 0.22 10.8 0.0 0.38 10.0 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain zf-rbx1 PF12678.7 KXL49823.1 - 0.39 11.0 1.5 0.93 9.8 1.5 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KXL49823.1 - 1.4 8.7 5.0 3.4 7.5 5.0 1.8 1 0 0 1 1 1 0 RING-like zinc finger p450 PF00067.22 KXL49824.1 - 2.4e-56 191.4 0.0 3.3e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SSP160 PF06933.11 KXL49826.1 - 0.27 9.4 13.1 0.32 9.2 13.1 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Glyco_hydro_43 PF04616.14 KXL49827.1 - 6.6e-27 94.6 0.0 1.1e-26 93.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 RRG8 PF17068.5 KXL49828.1 - 0.0013 18.2 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Required for respiratory growth protein 8 mitochondrial CLP_protease PF00574.23 KXL49829.1 - 2.9e-74 248.9 0.0 3.7e-74 248.5 0.0 1.1 1 0 0 1 1 1 1 Clp protease SDH_sah PF01972.16 KXL49829.1 - 0.059 12.4 0.0 0.093 11.7 0.0 1.2 1 0 0 1 1 1 0 Serine dehydrogenase proteinase SMC_N PF02463.19 KXL49831.1 - 6.8e-26 91.1 0.3 1.1e-25 90.4 0.3 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KXL49831.1 - 3.7e-11 43.9 56.5 1.5e-07 32.2 32.6 5.2 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.6 KXL49831.1 - 1.7e-08 34.6 8.1 1.7e-08 34.6 8.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KXL49831.1 - 2.4e-07 30.9 4.1 0.0028 17.5 0.0 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXL49831.1 - 0.00087 19.0 0.1 0.0019 17.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Adeno_IVa2 PF02456.15 KXL49831.1 - 0.0097 14.7 0.0 0.021 13.6 0.0 1.5 1 0 0 1 1 1 1 Adenovirus IVa2 protein Ploopntkinase3 PF18751.1 KXL49831.1 - 0.059 13.3 0.0 0.25 11.2 0.0 2.1 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_22 PF13401.6 KXL49831.1 - 6.3 7.1 7.9 7.4 6.8 0.1 3.6 4 0 0 4 4 4 0 AAA domain Cys_Met_Meta_PP PF01053.20 KXL49832.1 - 1.6e-29 102.6 0.0 2.3e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Caerin_1 PF07440.12 KXL49832.1 - 0.42 10.7 3.0 0.23 11.5 0.4 1.9 2 0 0 2 2 2 0 Caerin 1 protein Nrap_D4 PF17405.2 KXL49833.1 - 5.7e-64 215.4 0.2 1.1e-63 214.5 0.2 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 KXL49833.1 - 6e-54 182.2 0.8 1.2e-53 181.2 0.8 1.5 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap PF03813.14 KXL49833.1 - 1.9e-46 157.8 0.1 3.2e-46 157.1 0.1 1.4 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D2 PF17403.2 KXL49833.1 - 3.1e-42 143.9 0.0 1.4e-39 135.3 0.0 2.5 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap_D3 PF17404.2 KXL49833.1 - 8.2e-39 133.3 0.0 1.6e-38 132.3 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 KXL49833.1 - 3e-34 118.1 0.0 7.7e-34 116.8 0.0 1.8 1 0 0 1 1 1 1 Nrap protein domain 6 PCMT PF01135.19 KXL49834.1 - 1.1e-67 227.9 0.0 1.3e-67 227.7 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KXL49834.1 - 1.5e-06 28.1 0.0 2.4e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL49834.1 - 4.2e-05 24.2 0.0 8.3e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KXL49834.1 - 8.1e-05 22.7 0.0 0.00013 22.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXL49834.1 - 0.00038 20.3 0.0 0.0006 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXL49834.1 - 0.00047 19.6 0.0 0.00066 19.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KXL49834.1 - 0.0059 17.2 0.0 0.012 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 KXL49834.1 - 0.0079 15.3 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MetW PF07021.12 KXL49834.1 - 0.013 15.2 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW GCD14 PF08704.10 KXL49834.1 - 0.013 15.2 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit MTS PF05175.14 KXL49834.1 - 0.013 15.1 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.19 KXL49834.1 - 0.013 15.6 0.0 0.14 12.3 0.0 2.0 1 1 1 2 2 2 0 FtsJ-like methyltransferase Fibrillarin PF01269.17 KXL49834.1 - 0.049 12.7 0.0 0.089 11.9 0.0 1.4 1 0 0 1 1 1 0 Fibrillarin PrmA PF06325.13 KXL49834.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Sugar_tr PF00083.24 KXL49836.1 - 6.4e-68 229.7 23.1 8e-68 229.3 23.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL49836.1 - 2.7e-14 52.9 29.2 2.7e-14 52.9 29.2 2.5 1 1 1 3 3 3 1 Major Facilitator Superfamily Aldo_ket_red PF00248.21 KXL49838.1 - 3.6e-77 259.5 0.0 4.3e-77 259.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DnaJ PF00226.31 KXL49839.1 - 1.2e-07 31.7 0.1 2.3e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain adh_short_C2 PF13561.6 KXL49842.1 - 4.3e-58 196.6 1.2 6.4e-58 196.1 1.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL49842.1 - 2.3e-51 174.1 2.8 2.9e-51 173.7 2.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL49842.1 - 2.5e-13 50.3 1.0 3.3e-13 49.9 1.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL49842.1 - 0.011 15.2 0.6 0.017 14.6 0.6 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Peripla_BP_6 PF13458.6 KXL49842.1 - 0.029 14.0 0.2 0.044 13.4 0.2 1.2 1 0 0 1 1 1 0 Periplasmic binding protein THF_DHG_CYH_C PF02882.19 KXL49842.1 - 0.033 13.5 0.5 0.11 11.9 0.1 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.15 KXL49842.1 - 0.04 13.1 0.2 0.044 12.9 0.2 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Zn_clus PF00172.18 KXL49843.1 - 1.4e-08 34.7 13.4 3.7e-08 33.4 13.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KXL49843.1 - 2.8e-05 24.3 13.5 0.00012 22.3 1.8 4.0 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXL49843.1 - 0.00025 21.3 3.9 0.00025 21.3 3.9 4.4 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXL49843.1 - 0.0056 17.4 1.0 0.0056 17.4 1.0 4.5 4 1 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXL49843.1 - 1.2 9.6 3.9 14 6.1 0.3 3.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Cytochrom_CIII PF02085.16 KXL49843.1 - 1.7 9.0 7.4 3.7 7.9 7.4 1.5 1 0 0 1 1 1 0 Class III cytochrome C family Glycos_transf_1 PF00534.20 KXL49844.1 - 6.5e-29 100.7 0.0 8.8e-29 100.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXL49844.1 - 3.8e-25 88.9 0.1 6.1e-25 88.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXL49844.1 - 3.2e-09 37.0 0.1 5.4e-05 23.3 0.1 3.0 3 0 0 3 3 3 2 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KXL49844.1 - 6e-09 36.2 0.0 1.1e-07 32.1 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KXL49844.1 - 8.2e-09 36.1 1.2 2.1e-06 28.3 0.4 2.6 3 0 0 3 3 3 2 Glycosyl transferase 4-like domain UDPG_MGDP_dh_N PF03721.14 KXL49845.1 - 4.5e-38 130.7 0.0 8.4e-31 107.0 0.0 2.2 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 KXL49845.1 - 2.9e-32 110.7 0.0 4.8e-32 110.0 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 KXL49845.1 - 2e-24 86.0 0.0 9.6e-21 74.2 0.0 2.7 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain DEC-1_N PF04625.13 KXL49845.1 - 0.023 13.7 0.1 0.052 12.6 0.1 1.5 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Pkinase PF00069.25 KXL49846.1 - 1.2e-66 224.8 0.8 8.1e-66 222.1 0.8 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL49846.1 - 2.8e-52 177.6 0.0 4.6e-52 176.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KXL49846.1 - 2.1e-19 69.6 0.0 5.5e-19 68.3 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 KXL49846.1 - 2.1e-08 34.6 0.8 7e-08 32.9 0.1 2.1 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.6 KXL49846.1 - 2.5e-05 23.7 0.0 4.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXL49846.1 - 3.3e-05 22.9 0.0 3.3e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase PH_11 PF15413.6 KXL49846.1 - 0.17 12.3 0.2 0.89 10.0 0.2 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain PH_9 PF15410.6 KXL49846.1 - 0.23 11.8 2.9 33 4.9 0.2 3.3 2 1 0 2 2 2 0 Pleckstrin homology domain DUF4100 PF13352.6 KXL49846.1 - 0.41 10.4 7.2 0.91 9.3 7.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4100) APH PF01636.23 KXL49846.1 - 2.3 8.1 5.0 1.1 9.1 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family MFS_1 PF07690.16 KXL49847.1 - 6.9e-31 107.5 32.6 6.9e-31 107.5 32.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily LIDHydrolase PF10230.9 KXL49849.1 - 4.6e-58 196.9 0.0 5.5e-58 196.6 0.0 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 KXL49849.1 - 3.2e-06 27.9 2.5 4.5e-06 27.4 2.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXL49849.1 - 0.02 14.2 0.0 0.034 13.4 0.0 1.6 1 1 0 1 1 1 0 Serine aminopeptidase, S33 2-Hacid_dh_C PF02826.19 KXL49850.1 - 7.4e-51 172.0 0.0 1.1e-50 171.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXL49850.1 - 2.3e-36 124.4 0.0 3e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 KXL49850.1 - 0.00017 21.3 0.0 0.00039 20.1 0.0 1.6 1 0 0 1 1 1 1 ACT domain NAD_binding_2 PF03446.15 KXL49850.1 - 0.00047 20.4 1.1 0.0017 18.6 0.2 2.3 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 KXL49850.1 - 0.003 17.7 0.4 0.009 16.1 0.1 1.9 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 KXL49850.1 - 0.03 14.8 0.1 0.087 13.3 0.0 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain 3HCDH_N PF02737.18 KXL49850.1 - 0.11 12.3 1.8 9.5 6.1 0.4 2.7 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_2 PF00891.18 KXL49851.1 - 2e-22 79.6 0.1 2.2e-22 79.4 0.1 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 KXL49851.1 - 3.1e-05 23.8 0.2 4.4e-05 23.3 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase domain Coleoptericin PF06286.11 KXL49852.1 - 0.11 12.6 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Coleoptericin Glyco_hydro_31 PF01055.26 KXL49853.1 - 2e-90 304.1 4.4 3.2e-90 303.4 4.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 KXL49853.1 - 1.1e-05 25.6 0.0 2.5e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) Zn_clus PF00172.18 KXL49854.1 - 3.1e-08 33.6 8.2 6.3e-08 32.6 8.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXL49854.1 - 0.00032 19.8 0.4 0.00048 19.2 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_71 PF03659.14 KXL49855.1 - 4.3e-86 289.1 8.1 5.3e-86 288.8 8.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 COesterase PF00135.28 KXL49856.1 - 7.1e-06 25.2 0.0 7.9e-06 25.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family COesterase PF00135.28 KXL49857.1 - 6.7e-19 68.1 0.2 7.2e-19 68.0 0.2 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXL49857.1 - 0.0014 18.6 0.0 0.0016 18.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXL49857.1 - 0.07 12.6 0.0 0.076 12.5 0.0 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF883 PF05957.13 KXL49858.1 - 0.2 12.3 4.9 0.61 10.7 5.0 1.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) COesterase PF00135.28 KXL49859.1 - 3.1e-72 244.1 0.0 4e-72 243.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXL49859.1 - 2.8e-06 27.3 0.2 1.4e-05 25.0 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXL49859.1 - 0.0031 17.0 0.0 0.006 16.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_C14 PF00656.22 KXL49860.1 - 3.2e-63 214.0 0.0 4.2e-63 213.6 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KXL49860.1 - 0.14 12.1 0.1 0.54 10.2 0.0 2.0 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain HNH PF01844.23 KXL49863.1 - 0.0042 17.2 1.6 0.012 15.8 1.6 1.7 1 1 0 1 1 1 1 HNH endonuclease PP28 PF10252.9 KXL49864.1 - 1.3e-28 99.2 19.9 1.3e-28 99.2 19.9 3.2 2 1 1 3 3 3 2 Casein kinase substrate phosphoprotein PP28 CRAL_TRIO PF00650.20 KXL49865.1 - 1.4e-38 132.1 0.0 7.3e-38 129.8 0.0 1.9 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXL49865.1 - 8.1e-08 32.3 0.2 8.1e-08 32.3 0.2 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KXL49865.1 - 0.024 14.8 0.0 0.076 13.2 0.0 1.7 2 0 0 2 2 2 0 Divergent CRAL/TRIO domain Sel1 PF08238.12 KXL49867.1 - 3.7e-27 94.2 25.2 9e-09 35.7 0.0 7.7 6 2 1 7 7 7 7 Sel1 repeat TPR_1 PF00515.28 KXL49867.1 - 4.2e-05 23.2 5.9 0.0094 15.7 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXL49867.1 - 0.044 13.9 8.6 2.4 8.5 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXL49867.1 - 0.18 12.7 1.6 66 4.7 0.0 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat AAA PF00004.29 KXL49868.1 - 4.9e-45 153.2 0.4 1.4e-44 151.7 0.0 1.9 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KXL49868.1 - 3.4e-09 36.5 0.1 2.2e-08 33.9 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KXL49868.1 - 6.5e-09 35.9 0.5 2.7e-08 33.9 0.1 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KXL49868.1 - 5.9e-08 33.0 0.0 1.3e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KXL49868.1 - 1.9e-07 31.6 0.6 4.2e-05 24.0 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 KXL49868.1 - 3.4e-06 26.4 0.3 6.8e-06 25.4 0.0 1.7 2 0 0 2 2 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KXL49868.1 - 3.5e-05 24.1 1.3 0.0081 16.4 0.1 2.7 1 1 0 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 KXL49868.1 - 0.00018 21.2 0.0 0.0004 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KXL49868.1 - 0.00038 20.2 0.0 0.0011 18.8 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KXL49868.1 - 0.00087 19.8 0.0 0.0026 18.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 KXL49868.1 - 0.00095 19.4 0.0 0.002 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KXL49868.1 - 0.0012 18.1 0.0 0.0023 17.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_7 PF12775.7 KXL49868.1 - 0.0012 18.3 0.1 0.0071 15.9 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 KXL49868.1 - 0.0013 19.1 0.0 0.0031 17.9 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 KXL49868.1 - 0.0016 18.5 0.1 0.0087 16.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXL49868.1 - 0.0018 18.0 0.0 0.0041 16.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KXL49868.1 - 0.0026 17.7 0.0 0.012 15.5 0.0 2.0 2 0 0 2 2 2 1 NTPase TsaE PF02367.17 KXL49868.1 - 0.0065 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 KXL49868.1 - 0.0066 16.3 0.0 0.02 14.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KXL49868.1 - 0.0071 16.3 0.2 0.11 12.4 0.0 2.6 3 0 0 3 3 2 1 NACHT domain DUF3450 PF11932.8 KXL49868.1 - 0.0078 15.5 0.8 0.017 14.4 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Mg_chelatase PF01078.21 KXL49868.1 - 0.0081 15.6 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KXL49868.1 - 0.009 16.2 0.0 0.02 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 KXL49868.1 - 0.0098 15.3 0.0 0.55 9.6 0.0 2.4 2 0 0 2 2 2 1 Bacterial TniB protein IstB_IS21 PF01695.17 KXL49868.1 - 0.012 15.4 0.1 0.039 13.7 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 KXL49868.1 - 0.021 14.6 0.2 0.051 13.3 0.2 1.8 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KXL49868.1 - 0.036 14.0 1.3 0.23 11.4 0.1 2.6 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea ATPase PF06745.13 KXL49868.1 - 0.037 13.4 1.5 0.52 9.6 0.0 2.7 3 0 0 3 3 3 0 KaiC AAA_11 PF13086.6 KXL49868.1 - 0.041 13.7 0.2 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 KXL49868.1 - 0.066 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein AFG1_ATPase PF03969.16 KXL49868.1 - 0.078 11.9 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase Sigma54_activat PF00158.26 KXL49868.1 - 0.081 12.6 0.1 1.4 8.6 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain Viral_Hsp90 PF03225.14 KXL49868.1 - 0.089 11.3 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue AAA_25 PF13481.6 KXL49868.1 - 0.097 12.2 1.7 0.26 10.8 0.1 2.3 2 1 1 3 3 3 0 AAA domain AAA_23 PF13476.6 KXL49868.1 - 0.1 13.1 1.7 5.8 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KXL49868.1 - 0.12 12.7 0.3 0.41 11.0 0.1 2.0 2 0 0 2 2 1 0 AAA domain AAA_29 PF13555.6 KXL49868.1 - 0.17 11.7 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain CHD5 PF04420.14 KXL49868.1 - 0.18 11.7 2.7 0.57 10.0 2.7 1.8 1 1 0 1 1 1 0 CHD5-like protein Parvo_NS1 PF01057.17 KXL49868.1 - 0.2 10.7 0.0 0.39 9.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 WSC PF01822.19 KXL49870.1 - 6.4e-15 55.1 12.2 6.4e-15 55.1 12.2 1.9 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.10 KXL49870.1 - 5.5e-08 32.1 3.5 5.5e-08 32.1 3.5 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain MGC-24 PF05283.11 KXL49870.1 - 0.0053 17.2 9.2 0.012 16.0 9.2 1.7 1 1 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Trp_oprn_chp PF09534.10 KXL49870.1 - 0.0065 16.3 1.6 0.013 15.3 1.6 1.5 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4448 PF14610.6 KXL49870.1 - 0.0074 16.1 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) PetG PF02529.15 KXL49870.1 - 0.065 13.1 0.5 0.15 11.9 0.1 1.8 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 AJAP1_PANP_C PF15298.6 KXL49870.1 - 0.072 13.3 7.3 0.12 12.6 7.3 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus DUF3042 PF11240.8 KXL49870.1 - 0.09 12.8 0.1 0.35 10.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) DUF2207 PF09972.9 KXL49870.1 - 0.12 11.1 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Lgl_C PF08596.10 KXL49871.1 - 1.1e-120 403.0 0.0 1.3e-119 399.5 0.0 2.2 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 KXL49871.1 - 1.2e-08 35.5 0.3 0.0056 17.5 0.0 4.3 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL49871.1 - 1.8e-05 24.9 0.0 5.5 7.4 0.0 6.1 7 1 0 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain CSN8_PSD8_EIF3K PF10075.9 KXL49872.1 - 6.7e-37 126.7 0.0 9.6e-37 126.2 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family ASF1_hist_chap PF04729.13 KXL49873.1 - 1.3e-73 246.0 0.0 1.9e-73 245.5 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone FAD_binding_3 PF01494.19 KXL49876.1 - 7.8e-11 41.8 0.9 2.9e-10 40.0 0.9 1.8 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 KXL49876.1 - 0.003 16.6 0.0 1.3 8.0 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase FSH1 PF03959.13 KXL49877.1 - 1.5e-29 103.2 0.0 2e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KXL49877.1 - 0.052 13.3 0.9 1.9 8.3 0.1 2.8 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Imm74 PF15603.6 KXL49877.1 - 0.068 13.4 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 74 Abhydrolase_1 PF00561.20 KXL49877.1 - 0.085 12.5 0.0 0.15 11.7 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXL49877.1 - 0.16 12.6 4.5 0.91 10.1 4.5 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family R3H PF01424.22 KXL49878.1 - 1.3e-13 50.7 0.0 3.6e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 KXL49878.1 - 6.1e-11 42.0 4.2 1.6e-10 40.7 4.2 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KXL49878.1 - 0.0002 21.4 2.0 0.0002 21.4 2.0 3.7 4 0 0 4 4 4 1 G-patch domain RNA_pol_3_Rpc31 PF11705.8 KXL49878.1 - 0.0011 19.3 10.3 0.0011 19.3 10.3 4.1 3 1 0 3 3 3 1 DNA-directed RNA polymerase III subunit Rpc31 RNA_polI_A34 PF08208.11 KXL49878.1 - 0.0031 17.6 8.0 0.0031 17.6 8.0 3.5 3 0 0 3 3 3 1 DNA-directed RNA polymerase I subunit RPA34.5 MDM31_MDM32 PF08118.11 KXL49878.1 - 1.2 7.8 3.6 2 7.0 3.6 1.3 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins MAM33 PF02330.16 KXL49878.1 - 1.3 9.0 19.9 0.034 14.1 13.0 1.9 2 0 0 2 2 2 0 Mitochondrial glycoprotein Zip PF02535.22 KXL49878.1 - 1.4 8.1 2.9 3.3 6.8 2.9 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter DUF719 PF05334.13 KXL49878.1 - 2 8.6 9.6 0.23 11.6 4.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF719) Peptidase_C54 PF03416.19 KXL49879.1 - 4.6e-97 324.7 0.0 5.6e-97 324.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Histone PF00125.24 KXL49880.1 - 4.8e-23 82.0 1.3 5.9e-23 81.7 1.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXL49880.1 - 6.5e-05 23.1 1.0 0.00011 22.5 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXL49880.1 - 0.00027 21.4 0.0 0.00045 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.12 KXL49880.1 - 0.031 15.3 0.7 0.042 14.8 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) RP-C PF03428.13 KXL49880.1 - 0.058 13.0 0.1 0.14 11.8 0.1 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain Histone_H2A_C PF16211.5 KXL49881.1 - 3.7e-21 74.6 2.0 6.4e-21 73.8 2.0 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXL49881.1 - 4.3e-17 62.7 0.0 5.9e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXL49881.1 - 1e-05 25.7 0.0 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 2-oxoacid_dh PF00198.23 KXL49882.1 - 2e-79 266.4 0.1 3.1e-79 265.7 0.1 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KXL49882.1 - 5.5e-18 64.6 1.6 1e-17 63.7 1.6 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.6 KXL49882.1 - 0.0039 17.9 0.3 0.25 12.1 0.3 2.5 1 1 0 1 1 1 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 KXL49882.1 - 0.0048 16.7 0.5 1.8 8.5 0.2 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like GCV_H PF01597.19 KXL49882.1 - 0.0089 15.9 0.3 0.019 14.9 0.3 1.5 1 0 0 1 1 1 1 Glycine cleavage H-protein GAGA_bind PF06217.12 KXL49882.1 - 2.1 8.6 8.7 3 8.1 8.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Presenilin PF01080.17 KXL49882.1 - 2.3 6.9 8.6 3.1 6.5 8.6 1.1 1 0 0 1 1 1 0 Presenilin FAM76 PF16046.5 KXL49882.1 - 2.4 7.4 9.7 45 3.2 8.7 2.1 2 0 0 2 2 2 0 FAM76 protein DUF4551 PF15087.6 KXL49882.1 - 3.9 6.2 9.3 5.3 5.8 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CDC45 PF02724.14 KXL49882.1 - 6 5.0 9.0 7.3 4.7 9.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Ndc1_Nup PF09531.10 KXL49882.1 - 6.6 5.3 10.5 9.5 4.8 10.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RR_TM4-6 PF06459.12 KXL49882.1 - 7.8 6.2 14.8 11 5.7 14.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Complex1_LYR PF05347.15 KXL49883.1 - 1.9e-08 34.2 0.8 3e-08 33.6 0.6 1.5 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Aminotran_1_2 PF00155.21 KXL49884.1 - 4.3e-39 134.7 0.0 5.1e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 KXL49884.1 - 0.0037 16.0 0.0 0.0053 15.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-III Cys_Met_Meta_PP PF01053.20 KXL49884.1 - 0.019 13.5 0.0 0.027 13.0 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KXL49884.1 - 0.1 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_3 PF00202.21 KXL49885.1 - 1.5e-41 142.4 0.0 4.8e-20 71.6 0.0 3.1 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.6 KXL49885.1 - 3e-21 76.2 0.0 5e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF4142 PF13628.6 KXL49885.1 - 0.0051 17.1 0.3 0.012 15.8 0.3 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4142) RNA_helicase PF00910.22 KXL49885.1 - 0.11 12.9 0.1 0.4 11.1 0.0 2.1 2 0 0 2 2 2 0 RNA helicase CbiA PF01656.23 KXL49885.1 - 0.14 12.3 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VHS PF00790.19 KXL49886.1 - 1.4e-45 154.6 0.0 3.4e-45 153.4 0.0 1.7 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KXL49886.1 - 4.8e-21 74.9 2.2 1.5e-20 73.3 0.1 2.9 4 0 0 4 4 4 1 GAT domain Alpha_adaptinC2 PF02883.20 KXL49886.1 - 3.4e-19 69.2 0.1 3.4e-19 69.2 0.1 2.5 3 0 0 3 3 3 1 Adaptin C-terminal domain GGA_N-GAT PF18308.1 KXL49886.1 - 6.9e-08 32.0 0.1 5.5e-07 29.1 0.0 2.5 2 0 0 2 2 2 1 GGA N-GAT domain Coatamer_beta_C PF07718.12 KXL49886.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Coatomer beta C-terminal region Mei5 PF10376.9 KXL49886.1 - 0.12 12.3 1.1 0.24 11.2 1.1 1.5 1 0 0 1 1 1 0 Double-strand recombination repair protein DUF3324 PF11797.8 KXL49886.1 - 0.18 11.7 0.8 23 5.0 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function C-terminal (DUF3324) Ribo_biogen_C PF04034.13 KXL49888.1 - 1.9e-50 169.8 0.0 2.9e-50 169.2 0.0 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 KXL49888.1 - 2.5e-09 36.8 0.1 4e-09 36.1 0.1 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI MBOAT PF03062.19 KXL49890.1 - 2.5e-44 152.1 13.7 2.5e-44 152.1 13.7 1.7 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Prominin PF05478.11 KXL49890.1 - 0.02 12.9 0.8 0.028 12.4 0.8 1.1 1 0 0 1 1 1 0 Prominin MBOAT_2 PF13813.6 KXL49890.1 - 0.12 12.7 2.5 0.31 11.3 2.5 1.7 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family Actin PF00022.19 KXL49891.1 - 3.2e-127 424.5 0.0 3.7e-127 424.3 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KXL49891.1 - 0.18 10.6 0.0 3.1 6.5 0.0 2.4 3 0 0 3 3 3 0 MreB/Mbl protein PIP5K PF01504.18 KXL49892.1 - 3.8e-101 337.9 0.0 5.9e-101 337.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Linker_histone PF00538.19 KXL49893.1 - 7.5e-28 96.7 0.0 7.5e-28 96.7 0.0 2.3 3 0 0 3 3 3 1 linker histone H1 and H5 family CDC27 PF09507.10 KXL49893.1 - 4.6 6.5 30.5 6.8 6.0 30.5 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Mitofilin PF09731.9 KXL49893.1 - 8.4 5.1 21.3 8.7 5.0 21.3 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Proteasome PF00227.26 KXL49894.1 - 1.2e-45 155.3 0.1 2e-45 154.6 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KXL49894.1 - 2.3e-14 52.5 1.6 2.3e-14 52.5 1.6 1.7 2 0 0 2 2 2 1 Proteasome beta subunits C terminal NUP214 PF16755.5 KXL49895.1 - 1.2e-08 34.6 0.1 1.5e-07 31.0 0.1 2.2 2 0 0 2 2 2 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 Golgin_A5 PF09787.9 KXL49895.1 - 0.0012 18.3 7.9 0.0019 17.7 7.9 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 WXG100 PF06013.12 KXL49895.1 - 0.062 13.5 4.3 0.17 12.1 4.3 1.7 1 0 0 1 1 1 0 Proteins of 100 residues with WXG WD40 PF00400.32 KXL49895.1 - 0.068 14.1 0.0 5.6 8.0 0.0 2.8 2 0 0 2 2 2 0 WD domain, G-beta repeat Fez1 PF06818.15 KXL49895.1 - 0.081 13.4 4.6 0.15 12.5 4.6 1.4 1 0 0 1 1 1 0 Fez1 DUF4763 PF15960.5 KXL49895.1 - 0.15 11.4 4.9 0.31 10.3 4.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Baculo_F PF12259.8 KXL49895.1 - 0.18 10.3 2.1 0.26 9.7 2.1 1.1 1 0 0 1 1 1 0 Baculovirus F protein UPF0242 PF06785.11 KXL49895.1 - 1.8 8.7 10.7 13 5.8 10.6 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FapA PF03961.13 KXL49895.1 - 2.1 6.9 9.5 0.38 9.3 1.2 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF4407 PF14362.6 KXL49895.1 - 2.8 7.2 8.5 4.6 6.5 8.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HAUS-augmin3 PF14932.6 KXL49895.1 - 9.7 5.7 10.1 15 5.1 9.3 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 Rsa3 PF14615.6 KXL49896.1 - 3.8e-18 64.8 0.0 5.3e-18 64.3 0.0 1.2 1 0 0 1 1 1 1 Ribosome-assembly protein 3 CNOT1_TTP_bind PF16417.5 KXL49896.1 - 0.087 12.0 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 TTP binding domain ubiquitin PF00240.23 KXL49897.1 - 1.8e-13 50.0 0.0 2.9e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family zf-AN1 PF01428.16 KXL49897.1 - 1.3e-11 44.4 6.5 2.5e-11 43.6 6.5 1.5 1 1 0 1 1 1 1 AN1-like Zinc finger Rad60-SLD PF11976.8 KXL49897.1 - 1.7e-06 27.7 0.0 2.8e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KXL49897.1 - 0.0024 18.4 0.0 0.0031 18.0 0.0 1.4 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain Transp_Tc5_C PF04236.15 KXL49897.1 - 0.099 13.0 2.9 0.18 12.2 2.9 1.4 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain Ubiquitin_4 PF18036.1 KXL49897.1 - 0.19 11.8 0.0 1.7 8.8 0.0 2.1 1 1 1 2 2 2 0 Ubiquitin-like domain Ribosomal_S2 PF00318.20 KXL49899.1 - 6.6e-64 215.1 0.0 3.5e-63 212.7 0.0 2.0 1 1 0 1 1 1 1 Ribosomal protein S2 DUF3874 PF12990.7 KXL49900.1 - 0.61 10.5 2.1 8.7 6.8 0.0 3.5 4 0 0 4 4 4 0 Domain of unknonw function from B. Theta Gene description (DUF3874) Mito_carr PF00153.27 KXL49901.1 - 1.7e-53 178.5 0.5 1.8e-22 79.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein TBPIP PF07106.13 KXL49902.1 - 2.5e-16 59.3 0.1 4.2e-16 58.6 0.1 1.4 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain Penicillinase_R PF03965.16 KXL49902.1 - 0.012 16.0 0.4 0.024 15.0 0.4 1.6 1 1 0 1 1 1 0 Penicillinase repressor TFIIB PF00382.19 KXL49902.1 - 0.078 13.0 0.1 0.23 11.5 0.1 1.8 1 0 0 1 1 1 0 Transcription factor TFIIB repeat YabA PF06156.13 KXL49902.1 - 9 7.0 10.1 4.6 7.9 2.4 2.5 1 1 1 2 2 2 0 Initiation control protein YabA Abhydrolase_2 PF02230.16 KXL49903.1 - 9.4e-35 120.4 0.0 1.3e-34 119.9 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase BAAT_C PF08840.11 KXL49903.1 - 0.001 19.0 0.0 0.0028 17.6 0.0 1.6 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Cutinase PF01083.22 KXL49903.1 - 0.012 15.6 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 Cutinase FSH1 PF03959.13 KXL49903.1 - 0.013 15.1 0.0 0.025 14.2 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 KXL49903.1 - 0.026 13.8 0.0 4.5 6.5 0.0 2.8 2 1 1 3 3 3 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KXL49903.1 - 0.034 14.0 0.0 0.71 9.7 0.0 2.3 2 1 1 3 3 3 0 alpha/beta hydrolase fold zf-HIT PF04438.16 KXL49904.1 - 2.3e-08 33.7 6.2 3.4e-08 33.2 6.2 1.2 1 0 0 1 1 1 1 HIT zinc finger CP2 PF04516.15 KXL49905.1 - 4.7e-81 271.5 0.0 1.1e-80 270.2 0.0 1.6 2 0 0 2 2 2 1 CP2 transcription factor Tektin PF03148.14 KXL49905.1 - 0.1 11.3 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Tektin family Paramyxo_P PF01806.17 KXL49906.1 - 0.005 16.3 0.1 0.0076 15.7 0.1 1.2 1 0 0 1 1 1 1 Paramyxovirinae P phosphoprotein C-terminal region DUF3437 PF11919.8 KXL49906.1 - 0.13 12.2 0.0 0.45 10.5 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) ERM PF00769.19 KXL49906.1 - 0.19 11.5 6.2 0.31 10.8 6.2 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Ribosomal_L29e PF01779.17 KXL49907.1 - 2.3e-22 79.0 11.1 3.4e-22 78.5 11.1 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family Aconitase PF00330.20 KXL49908.1 - 1e-148 496.2 0.0 1.3e-148 495.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KXL49908.1 - 2.4e-45 154.1 0.0 4e-45 153.3 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-C2H2_jaz PF12171.8 KXL49909.1 - 5.7e-10 39.2 1.9 5.7e-10 39.2 1.9 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXL49909.1 - 4.4e-05 23.7 5.9 5.2e-05 23.5 0.7 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-U1 PF06220.12 KXL49909.1 - 0.0087 15.8 0.1 0.0087 15.8 0.1 2.0 3 0 0 3 3 3 1 U1 zinc finger zf-C2H2_2 PF12756.7 KXL49909.1 - 0.04 14.2 3.6 0.12 12.7 3.0 1.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KXL49909.1 - 0.058 14.3 2.4 0.11 13.4 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger DUF4381 PF14316.6 KXL49909.1 - 0.19 12.0 2.4 5.7 7.2 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) zf-H2C2_2 PF13465.6 KXL49909.1 - 2.1 8.9 4.9 1.9 9.1 0.9 2.6 2 1 0 2 2 2 0 Zinc-finger double domain eIF2A PF08662.11 KXL49910.1 - 8.5e-83 277.0 0.1 1.1e-81 273.4 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 KXL49910.1 - 0.00021 22.0 0.2 1.9 9.5 0.1 5.1 3 2 1 5 5 5 1 WD domain, G-beta repeat PD40 PF07676.12 KXL49910.1 - 0.00068 19.5 0.5 4.3 7.4 0.0 4.8 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 KXL49910.1 - 0.37 10.5 1.2 29 4.5 0.0 3.5 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Methyltransf_2 PF00891.18 KXL49911.1 - 7.6e-14 51.5 0.0 4e-13 49.2 0.0 1.9 2 0 0 2 2 2 1 O-methyltransferase domain Dimerisation PF08100.11 KXL49911.1 - 0.0093 16.0 0.3 0.027 14.5 0.3 1.8 1 0 0 1 1 1 1 Dimerisation domain FeoC PF09012.10 KXL49911.1 - 0.032 14.3 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 FeoC like transcriptional regulator Dimerisation2 PF16864.5 KXL49911.1 - 0.04 13.9 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 Dimerisation domain UDG PF03167.19 KXL49913.1 - 1.4e-22 80.4 0.2 3.1e-22 79.2 0.1 1.6 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily Ig_mannosidase PF17753.1 KXL49914.1 - 5e-23 80.7 0.7 1.2e-22 79.4 0.7 1.7 1 0 0 1 1 1 1 Ig-fold domain Mannosidase_ig PF17786.1 KXL49914.1 - 2.8e-09 37.4 0.0 9.9e-09 35.7 0.0 2.0 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KXL49914.1 - 0.00011 22.8 0.0 0.00031 21.4 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 DUF4217 PF13959.6 KXL49914.1 - 0.0039 17.4 0.0 0.0084 16.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Cuticle_1 PF08140.11 KXL49915.1 - 0.13 12.3 0.1 0.38 10.8 0.0 1.8 2 0 0 2 2 2 0 Crustacean cuticle protein repeat ECH_1 PF00378.20 KXL49916.1 - 2.8e-46 157.9 0.0 6.5e-46 156.7 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXL49916.1 - 4e-25 89.0 0.0 4.7e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Ribonuclease_T2 PF00445.18 KXL49917.1 - 8.6e-41 140.2 1.2 1.9e-40 139.1 1.2 1.5 1 0 0 1 1 1 1 Ribonuclease T2 family MFS_1 PF07690.16 KXL49918.1 - 1.3e-12 47.4 17.1 1.3e-12 47.4 17.1 3.0 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL49918.1 - 1.4e-06 27.5 1.1 1.4e-06 27.5 1.1 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter MerE PF05052.12 KXL49918.1 - 0.019 14.8 0.6 0.13 12.2 0.1 2.6 2 0 0 2 2 2 0 MerE protein DUF3671 PF12420.8 KXL49918.1 - 1.1 9.4 5.6 8.8 6.4 1.1 2.9 3 0 0 3 3 3 0 Protein of unknown function FAD_binding_3 PF01494.19 KXL49920.1 - 1.4e-09 37.7 1.1 9.1e-08 31.7 0.4 2.5 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KXL49920.1 - 6.4e-07 28.9 0.2 3.5e-06 26.5 0.2 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXL49920.1 - 9.6e-07 28.9 0.2 2.3e-06 27.7 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXL49920.1 - 1.2e-05 24.7 1.2 1.8e-05 24.0 1.2 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXL49920.1 - 1.7e-05 24.6 1.9 5.9e-05 22.8 0.6 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXL49920.1 - 0.00022 21.7 0.2 0.00065 20.2 0.2 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXL49920.1 - 0.0013 17.8 1.7 0.0042 16.2 1.7 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.14 KXL49920.1 - 0.0016 17.4 0.2 0.17 10.7 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase AlaDh_PNT_C PF01262.21 KXL49920.1 - 0.0017 17.7 0.0 0.0033 16.8 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KXL49920.1 - 0.0024 16.7 0.5 0.0035 16.1 0.5 1.6 1 1 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 KXL49920.1 - 0.01 14.9 0.1 0.017 14.3 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KXL49920.1 - 0.017 14.5 0.3 0.027 13.8 0.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXL49920.1 - 0.018 14.3 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXL49920.1 - 0.022 14.1 0.1 1.7 7.9 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KXL49920.1 - 0.034 14.1 2.9 7.8 6.5 0.1 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding MCRA PF06100.11 KXL49920.1 - 0.12 11.1 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 MCRA family Zn_clus PF00172.18 KXL49922.1 - 3.3e-09 36.7 8.6 7.1e-09 35.7 8.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXL49922.1 - 3.1e-07 29.7 0.9 1.4e-06 27.6 0.9 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain HTH_3 PF01381.22 KXL49922.1 - 0.19 11.8 0.0 0.44 10.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix tRNA-synt_2b PF00587.25 KXL49923.1 - 3.8e-32 111.7 0.0 8.7e-29 100.7 0.0 3.2 3 0 0 3 3 3 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KXL49923.1 - 1.3e-16 60.6 0.2 3.3e-16 59.2 0.2 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 KXL49923.1 - 5.3e-14 52.0 0.0 1.1e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 KXL49923.1 - 3.6e-13 49.3 0.0 7e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 TGS domain Ytp1 PF10355.9 KXL49924.1 - 3.6e-105 351.1 12.1 6.5e-105 350.3 12.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KXL49924.1 - 9.7e-24 83.2 3.8 9.7e-24 83.2 3.8 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Zip PF02535.22 KXL49924.1 - 0.013 14.8 0.0 0.036 13.3 0.0 1.8 1 0 0 1 1 1 0 ZIP Zinc transporter CRAL_TRIO PF00650.20 KXL49926.1 - 1.8e-44 151.2 0.0 4.2e-44 150.1 0.0 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXL49926.1 - 2.9e-14 53.0 0.2 1.1e-13 51.2 0.2 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KXL49926.1 - 2.1e-07 31.2 0.0 3.3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DASH_Dam1 PF08653.10 KXL49927.1 - 7.9e-27 92.8 1.9 1.1e-26 92.4 1.9 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 NAPRTase_N PF17767.1 KXL49927.1 - 0.035 14.5 0.0 0.041 14.3 0.0 1.0 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Glyco_hydro_47 PF01532.20 KXL49928.1 - 1.8e-185 617.2 0.1 2.1e-185 617.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Cupin_2 PF07883.11 KXL49929.1 - 1.1e-07 31.4 0.2 3.2e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KXL49929.1 - 0.00045 19.8 0.0 0.00071 19.2 0.0 1.3 1 1 0 1 1 1 1 Cupin DUF1971 PF09313.11 KXL49929.1 - 0.077 13.0 0.0 0.47 10.5 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1971) DUF386 PF04074.12 KXL49929.1 - 0.17 11.7 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 YhcH/YjgK/YiaL Glyco_hydro_72 PF03198.14 KXL49930.1 - 3.1e-130 434.0 7.3 4.2e-130 433.6 7.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KXL49930.1 - 1.7e-23 83.1 7.3 1.7e-23 83.1 7.3 2.2 2 0 0 2 2 2 1 X8 domain Glucan_synthase PF02364.15 KXL49931.1 - 0 1374.8 0.0 0 1374.4 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KXL49931.1 - 1.7e-41 141.6 0.5 4.4e-41 140.2 0.5 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 zf-H2C2 PF09337.10 KXL49932.1 - 5.5e-16 58.5 1.3 1.1e-15 57.6 1.3 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 KXL49932.1 - 5.9e-11 42.3 0.1 3.8e-10 39.7 0.2 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 KXL49932.1 - 0.00026 21.2 0.0 0.00053 20.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KXL49932.1 - 0.019 15.1 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Suf PF05843.14 KXL49932.1 - 0.023 14.7 6.0 0.036 14.1 6.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Acetyltransf_3 PF13302.7 KXL49932.1 - 0.04 14.6 0.0 0.1 13.3 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RVP PF00077.20 KXL49932.1 - 0.044 14.1 1.5 0.1 13.0 1.5 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease TraG_N PF07916.11 KXL49932.1 - 1.6 7.5 5.1 2.5 6.9 5.1 1.2 1 0 0 1 1 1 0 TraG-like protein, N-terminal region TFIIA PF03153.13 KXL49932.1 - 2.3 8.2 14.3 3 7.7 14.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_M23 PF01551.22 KXL49933.1 - 0.1 12.8 0.0 0.47 10.7 0.0 2.1 2 0 0 2 2 2 0 Peptidase family M23 VEGF_C PF14554.6 KXL49933.1 - 0.52 10.5 4.1 0.32 11.1 1.0 2.4 2 0 0 2 2 2 0 VEGF heparin-binding domain TLD PF07534.16 KXL49934.1 - 6e-26 91.3 0.0 4.9e-14 52.7 0.0 2.2 2 0 0 2 2 2 2 TLD Med14 PF08638.11 KXL49935.1 - 1.5e-56 190.8 0.7 2.5e-56 190.1 0.1 1.7 2 0 0 2 2 2 1 Mediator complex subunit MED14 UCH PF00443.29 KXL49937.1 - 7.6e-52 176.3 0.0 1.4e-51 175.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXL49937.1 - 1e-19 71.3 3.9 1.8e-18 67.2 0.6 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KXL49937.1 - 3.8e-06 27.1 2.1 3.5e-05 24.1 2.1 2.7 1 1 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Peptidase_C98 PF15499.6 KXL49937.1 - 0.041 13.4 1.2 11 5.3 0.0 3.2 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Velvet PF11754.8 KXL49938.1 - 1.3e-48 166.2 0.3 5.1e-30 105.2 0.0 2.0 1 1 1 2 2 2 2 Velvet factor DUF3645 PF12359.8 KXL49938.1 - 0.035 13.5 0.1 1 8.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3645) Isy1 PF06246.12 KXL49939.1 - 1.7e-82 276.8 0.0 2.1e-82 276.6 0.0 1.1 1 0 0 1 1 1 1 Isy1-like splicing family Rotamase PF00639.21 KXL49940.1 - 2.4e-21 76.5 0.1 3.1e-21 76.1 0.1 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KXL49940.1 - 8.1e-15 55.4 0.0 1e-14 55.0 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 KXL49940.1 - 4.1e-10 39.6 3.1 4.1e-10 39.6 3.1 1.9 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 KXL49940.1 - 0.0071 17.2 0.0 0.0094 16.8 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW_1 PF18507.1 KXL49940.1 - 0.022 14.4 1.6 0.037 13.7 1.6 1.4 1 0 0 1 1 1 0 WW domain TFIIS_C PF01096.18 KXL49941.1 - 2.3e-13 49.7 2.7 2.3e-13 49.7 2.7 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KXL49941.1 - 1.9e-12 46.8 4.0 1.9e-12 46.8 4.0 2.7 3 0 0 3 3 3 2 RNA polymerases M/15 Kd subunit GFA PF04828.14 KXL49941.1 - 0.0067 16.7 8.3 0.28 11.6 0.1 2.6 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.7 KXL49941.1 - 0.058 13.4 10.6 0.072 13.1 1.4 2.7 1 1 2 3 3 3 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.7 KXL49941.1 - 0.29 11.1 7.0 0.86 9.6 0.5 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain VP_N-CPKC PF11475.8 KXL49941.1 - 1.3 9.0 7.9 17 5.4 0.2 3.4 3 0 0 3 3 3 0 Virion protein N terminal domain zf-RRN7 PF11781.8 KXL49941.1 - 1.5 8.6 11.1 14 5.4 0.1 4.0 4 0 0 4 4 4 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Ribosomal_L37e PF01907.19 KXL49941.1 - 1.6 9.0 6.5 6 7.1 0.1 3.0 2 1 0 2 2 2 0 Ribosomal protein L37e OrfB_Zn_ribbon PF07282.11 KXL49941.1 - 3.5 7.6 9.9 1.4 8.9 1.4 2.7 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Rubredoxin_2 PF18073.1 KXL49941.1 - 7.5 6.4 11.4 41 4.0 0.2 4.2 4 0 0 4 4 4 0 Rubredoxin metal binding domain SET PF00856.28 KXL49943.1 - 4.1e-10 40.3 1.0 1.2e-07 32.3 0.2 3.6 2 1 0 2 2 2 1 SET domain DUF2072 PF09845.9 KXL49943.1 - 0.15 12.3 1.7 0.57 10.5 1.7 2.0 1 0 0 1 1 1 0 Zn-ribbon containing protein Ribosomal_L14 PF00238.19 KXL49944.1 - 6.4e-48 161.9 1.8 7.1e-48 161.7 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e PH PF00169.29 KXL49945.1 - 8.3e-12 45.6 0.0 2.8e-11 43.8 0.0 2.0 1 0 0 1 1 1 1 PH domain Anillin PF08174.11 KXL49945.1 - 7.5e-09 36.1 0.0 2e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 Cell division protein anillin DUF3486 PF11985.8 KXL49945.1 - 0.053 13.9 0.2 0.13 12.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) PH_9 PF15410.6 KXL49945.1 - 0.089 13.2 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain DEAD PF00270.29 KXL49946.1 - 4.7e-32 111.2 0.1 1.2e-31 109.9 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXL49946.1 - 1.8e-15 57.3 0.1 8.8e-15 55.0 0.1 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL49946.1 - 0.00014 21.9 0.0 0.00058 19.9 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit adh_short PF00106.25 KXL49947.1 - 2.4e-29 102.2 0.0 5.6e-24 84.7 0.0 2.4 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXL49947.1 - 1.7e-22 80.1 0.0 6.1e-17 61.9 0.0 2.4 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL49947.1 - 2.8e-06 27.4 0.0 4.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL49947.1 - 0.038 13.4 0.0 0.17 11.4 0.0 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family AT_hook PF02178.19 KXL49947.1 - 0.15 12.0 2.4 0.38 10.8 2.4 1.7 1 0 0 1 1 1 0 AT hook motif UCH PF00443.29 KXL49948.1 - 6e-33 114.4 0.0 1.2e-32 113.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXL49948.1 - 1.5e-09 37.9 0.1 8.5e-08 32.2 0.1 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3517 PF12030.8 KXL49948.1 - 0.0026 16.8 0.5 0.024 13.6 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3517) PI3_PI4_kinase PF00454.27 KXL49949.1 - 1.6e-35 123.1 0.0 1.8e-34 119.7 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 KXL49949.1 - 2.4e-18 65.8 0.0 5.6e-18 64.6 0.0 1.7 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 DUF4135 PF13575.6 KXL49949.1 - 0.0015 17.9 0.0 0.003 17.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) PI3Ka PF00613.20 KXL49949.1 - 0.11 11.9 0.2 0.22 10.9 0.2 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF155 PF02582.14 KXL49950.1 - 4.3e-53 180.0 1.1 6.6e-53 179.4 1.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.6 KXL49950.1 - 0.11 13.0 0.0 0.34 11.4 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Lipase_GDSL_2 PF13472.6 KXL49951.1 - 1.3e-25 90.9 0.0 9.4e-25 88.0 0.0 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXL49951.1 - 2.3e-13 50.6 0.0 3.3e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF1896 PF08989.10 KXL49951.1 - 0.057 13.5 0.3 0.1 12.7 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1896) Flu_PB2 PF00604.17 KXL49951.1 - 0.3 9.0 0.0 0.4 8.5 0.0 1.1 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB2 SH3_1 PF00018.28 KXL49952.1 - 7.8e-16 57.4 0.1 1.6e-15 56.5 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXL49952.1 - 1.1e-13 50.8 0.2 2.1e-13 49.9 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXL49952.1 - 4.1e-12 45.6 0.1 7.8e-12 44.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.18 KXL49952.1 - 1.5e-06 28.0 3.4 2.7e-06 27.2 3.4 1.3 1 0 0 1 1 1 1 BAR domain CTK3 PF12243.8 KXL49953.1 - 8.2e-45 151.8 0.0 1.2e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 KXL49953.1 - 2.3e-20 72.5 8.7 4.8e-20 71.5 8.7 1.5 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus Retrotrans_gag PF03732.17 KXL49953.1 - 0.19 12.0 0.8 0.6 10.4 0.2 2.0 2 0 0 2 2 2 0 Retrotransposon gag protein SAP PF02037.27 KXL49954.1 - 0.00014 21.6 0.1 0.00028 20.6 0.1 1.6 1 0 0 1 1 1 1 SAP domain Rho_N PF07498.12 KXL49954.1 - 0.024 14.5 0.1 0.045 13.7 0.1 1.4 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain CDC45 PF02724.14 KXL49954.1 - 0.72 8.1 7.1 1.1 7.4 7.1 1.2 1 0 0 1 1 1 0 CDC45-like protein CDC27 PF09507.10 KXL49954.1 - 0.83 9.0 14.8 0.42 9.9 8.4 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 XRN_M PF17846.1 KXL49954.1 - 6.9 5.5 5.4 10 4.9 5.4 1.2 1 0 0 1 1 1 0 Xrn1 helical domain ArfGap PF01412.18 KXL49955.1 - 1.7e-27 95.8 0.0 3.4e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Spore_III_AE PF09546.10 KXL49956.1 - 0.057 12.6 0.2 0.071 12.3 0.2 1.0 1 0 0 1 1 1 0 Stage III sporulation protein AE (spore_III_AE) Csm1_B PF18211.1 KXL49958.1 - 0.16 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Csm1 subunit domain B Ion_trans_2 PF07885.16 KXL49959.1 - 0.022 14.7 3.1 0.96 9.5 0.0 3.1 3 0 0 3 3 3 0 Ion channel DUF3937 PF13073.6 KXL49959.1 - 5.4 7.2 7.0 1.2 9.3 1.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3937) FAD_binding_4 PF01565.23 KXL49960.1 - 6.5e-22 77.8 2.6 1.8e-21 76.4 2.6 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXL49960.1 - 4.5e-11 42.7 3.0 6.7e-11 42.1 0.7 2.2 2 0 0 2 2 2 1 Berberine and berberine like Zn_clus PF00172.18 KXL49962.1 - 7.6e-08 32.4 8.6 1.5e-07 31.4 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1772 PF08592.11 KXL49963.1 - 2.1e-05 24.9 2.3 4.6e-05 23.8 2.3 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) adh_short_C2 PF13561.6 KXL49964.1 - 9.8e-38 130.0 2.5 2.5e-37 128.7 2.5 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL49964.1 - 9.8e-30 103.5 0.8 1.5e-29 102.8 0.8 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL49964.1 - 6.9e-06 26.1 0.4 1.3e-05 25.2 0.4 1.4 1 0 0 1 1 1 1 KR domain DIOX_N PF14226.6 KXL49965.1 - 4.6e-16 59.6 0.0 5.5e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXL49966.1 - 2.5e-15 56.8 0.0 2.9e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-CCCH PF00642.24 KXL49967.1 - 1.2e-08 34.7 2.4 2.7e-08 33.5 2.4 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.6 KXL49967.1 - 1.6e-07 31.0 9.6 3.1e-07 30.1 9.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXL49967.1 - 1.7e-07 31.0 11.0 3.2e-07 30.1 11.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXL49967.1 - 6.8e-07 29.2 7.3 1.3e-06 28.3 7.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXL49967.1 - 6.9e-07 29.0 7.7 1.4e-06 28.1 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXL49967.1 - 1e-06 28.6 10.3 1.8e-06 27.8 10.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KXL49967.1 - 4.4e-06 26.9 7.6 8.7e-06 26.0 7.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf_CCCH_4 PF18345.1 KXL49967.1 - 1.8e-05 24.6 5.4 3.8e-05 23.6 5.4 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4_4 PF15227.6 KXL49967.1 - 3.3e-05 24.0 7.8 7.5e-05 22.8 7.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-CCCH_4 PF18044.1 KXL49967.1 - 0.00086 19.0 1.9 0.00086 19.0 1.9 2.1 2 0 0 2 2 2 1 CCCH-type zinc finger zf-Nse PF11789.8 KXL49967.1 - 0.0091 15.8 4.7 0.018 14.9 4.7 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 KXL49967.1 - 0.016 15.3 4.8 0.016 15.3 4.8 1.7 2 0 0 2 2 2 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 KXL49967.1 - 0.022 14.6 5.0 0.044 13.6 5.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-CCCH_2 PF14608.6 KXL49967.1 - 0.048 14.1 2.5 0.11 13.0 2.5 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger AMP-binding PF00501.28 KXL49968.1 - 2.1e-71 240.8 0.0 2.6e-71 240.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXL49968.1 - 4.8e-16 59.5 0.0 9e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PHF5 PF03660.14 KXL49969.1 - 2.8e-51 172.1 10.2 3.1e-51 171.9 10.2 1.0 1 0 0 1 1 1 1 PHF5-like protein C1_2 PF03107.16 KXL49969.1 - 0.64 10.4 19.0 1.6 9.1 8.3 2.9 1 1 1 2 2 2 0 C1 domain PolC_DP2 PF03833.13 KXL49969.1 - 1.5 6.6 8.1 0.049 11.5 2.2 1.4 1 1 1 2 2 2 0 DNA polymerase II large subunit DP2 DZR PF12773.7 KXL49969.1 - 2.8 8.0 16.0 5.9 7.0 2.0 3.0 1 1 1 2 2 2 0 Double zinc ribbon PRCC PF10253.9 KXL49970.1 - 9e-28 98.5 8.1 9e-28 98.5 8.1 1.7 1 1 1 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting Methyltransf_31 PF13847.6 KXL49971.1 - 4.1e-20 72.1 0.0 6.1e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL49971.1 - 6.2e-16 58.8 0.1 1.9e-15 57.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL49971.1 - 9.3e-16 58.3 0.2 8.2e-15 55.3 0.1 2.3 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXL49971.1 - 4.1e-11 42.7 0.0 5.5e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KXL49971.1 - 1.1e-10 42.2 0.0 2.3e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXL49971.1 - 0.00012 21.9 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXL49971.1 - 0.0032 16.9 0.0 0.0074 15.8 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase MetW PF07021.12 KXL49971.1 - 0.0046 16.6 0.1 0.0073 15.9 0.1 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW UPF0020 PF01170.18 KXL49971.1 - 0.063 12.9 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_3 PF01596.17 KXL49971.1 - 0.081 12.1 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_32 PF13679.6 KXL49971.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_24 PF13578.6 KXL49971.1 - 0.17 13.0 0.7 0.5 11.4 0.1 1.9 2 1 0 2 2 2 0 Methyltransferase domain WSC PF01822.19 KXL49973.1 - 1.2e-09 38.3 10.1 2.7e-09 37.1 10.1 1.6 1 0 0 1 1 1 1 WSC domain Mucin15 PF15672.5 KXL49973.1 - 0.008 15.7 4.6 0.015 14.8 4.6 1.5 1 0 0 1 1 1 1 Cell-membrane associated Mucin15 Gram_pos_anchor PF00746.21 KXL49973.1 - 0.011 15.7 1.7 0.011 15.7 1.7 2.4 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DUF3325 PF11804.8 KXL49973.1 - 1.6 9.0 5.4 0.51 10.5 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3325) Solute_trans_a PF03619.16 KXL49975.1 - 8.3e-91 304.2 20.1 9.8e-91 303.9 20.1 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Cation_efflux PF01545.21 KXL49975.1 - 0.0056 16.4 0.5 0.0097 15.7 0.5 1.3 1 1 0 1 1 1 1 Cation efflux family TssN PF17555.2 KXL49975.1 - 0.37 10.1 11.9 0.025 14.0 1.3 2.3 2 0 0 2 2 2 0 Type VI secretion system, TssN GATase PF00117.28 KXL49976.1 - 2.1e-46 158.1 0.0 2.9e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 KXL49976.1 - 1.1e-45 154.6 0.0 3.4e-45 153.0 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 KXL49976.1 - 1.4e-05 25.0 0.1 0.00068 19.4 0.1 2.4 1 1 0 1 1 1 1 Peptidase C26 zf-RING_UBOX PF13445.6 KXL49977.1 - 4.4e-08 33.0 10.9 5.2e-05 23.2 1.0 3.2 2 1 1 3 3 3 2 RING-type zinc-finger zf-NOSIP PF15906.5 KXL49977.1 - 4.7e-07 29.8 0.2 1.3e-06 28.5 0.0 1.8 2 0 0 2 2 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_2 PF13639.6 KXL49977.1 - 9.5e-06 25.9 16.4 0.0022 18.3 4.7 3.3 3 1 0 3 3 3 2 Ring finger domain zf-C3HC4_3 PF13920.6 KXL49977.1 - 1e-05 25.3 20.5 0.00059 19.6 7.2 3.0 3 1 0 3 3 2 2 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 KXL49977.1 - 4.1e-05 23.6 2.4 4.1e-05 23.6 2.4 2.6 2 1 0 2 2 2 1 FYVE zinc finger zf-RING_5 PF14634.6 KXL49977.1 - 0.00012 22.0 17.5 0.00015 21.6 6.5 2.7 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KXL49977.1 - 0.00036 20.3 20.1 0.0015 18.3 1.8 3.4 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXL49977.1 - 0.00071 19.4 17.1 0.0061 16.4 4.4 3.2 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXL49977.1 - 0.0094 15.8 19.8 0.095 12.6 8.6 3.9 2 2 1 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KXL49977.1 - 0.018 15.2 15.4 0.33 11.1 5.8 3.0 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING IBR PF01485.21 KXL49977.1 - 0.22 11.8 12.4 3.6 7.9 0.5 3.3 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Rtf2 PF04641.12 KXL49977.1 - 0.25 10.7 14.5 0.023 14.1 2.1 2.6 1 1 2 3 3 3 0 Rtf2 RING-finger zf-TFIIIC PF12660.7 KXL49977.1 - 0.27 11.2 0.1 0.27 11.2 0.1 2.5 2 1 0 2 2 2 0 Putative zinc-finger of transcription factor IIIC complex zf-4CXXC_R1 PF10497.9 KXL49977.1 - 0.85 9.9 7.2 0.26 11.5 1.7 2.4 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-C3HC4_5 PF17121.5 KXL49977.1 - 0.97 9.4 5.9 0.11 12.4 0.8 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 KXL49977.1 - 1.9 8.5 12.2 1.3 9.0 2.0 3.3 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 FYDLN_acid PF09538.10 KXL49977.1 - 3.7 8.3 12.4 0.2 12.3 2.6 3.4 3 2 0 3 3 3 0 Protein of unknown function (FYDLN_acid) zinc-ribbons_6 PF07191.12 KXL49977.1 - 9 6.4 12.2 4.9 7.2 5.5 3.2 2 1 0 2 2 2 0 zinc-ribbons GPS PF01825.21 KXL49978.1 - 0.03 14.9 1.5 0.033 14.7 0.1 1.7 2 0 0 2 2 2 0 GPCR proteolysis site, GPS, motif CBFD_NFYB_HMF PF00808.23 KXL49979.1 - 2.9e-11 43.5 2.3 2.3e-10 40.6 2.3 2.0 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PTR2 PF00854.21 KXL49980.1 - 0.039 12.8 0.0 0.042 12.7 0.0 1.1 1 0 0 1 1 1 0 POT family Pkinase PF00069.25 KXL49982.1 - 1.5e-07 31.1 0.0 1.5e-07 31.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Seadorna_VP7 PF07387.11 KXL49982.1 - 0.055 12.5 0.0 0.062 12.3 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_Tyr PF07714.17 KXL49982.1 - 0.23 10.7 0.0 0.24 10.6 0.0 1.0 1 0 0 1 1 1 0 Protein tyrosine kinase RRM_1 PF00076.22 KXL49983.1 - 4.3e-29 100.1 0.0 2.9e-15 55.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXL49983.1 - 9.3e-05 22.0 0.0 0.012 15.2 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXL49983.1 - 0.0018 18.4 0.0 0.21 11.7 0.0 2.7 2 1 0 2 2 2 1 RNA recognition motif DbpA PF03880.15 KXL49983.1 - 0.011 15.7 0.1 4.6 7.3 0.0 2.4 2 0 0 2 2 2 0 DbpA RNA binding domain Limkain-b1 PF11608.8 KXL49983.1 - 0.055 13.6 0.1 18 5.5 0.0 2.7 3 0 0 3 3 3 0 Limkain b1 PHM7_cyt PF14703.6 KXL49983.1 - 0.08 13.2 0.0 18 5.5 0.0 2.9 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Flavodoxin_1 PF00258.25 KXL49984.1 - 1.6e-30 106.2 0.0 4e-30 104.9 0.0 1.7 2 0 0 2 2 2 1 Flavodoxin FAD_binding_1 PF00667.20 KXL49984.1 - 3.9e-24 85.5 0.0 6.3e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KXL49984.1 - 5.2e-15 56.0 0.0 2e-14 54.1 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KXL49984.1 - 0.045 14.0 0.0 7 6.9 0.0 3.3 3 1 1 4 4 4 0 Flavodoxin domain Flavodoxin_3 PF12641.7 KXL49984.1 - 0.047 13.4 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Flavodoxin domain PLA2_B PF01735.18 KXL49985.1 - 7.1e-112 374.3 6.1 9.4e-112 373.9 6.1 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain zf-C3HC4 PF00097.25 KXL49986.1 - 7.1e-08 32.2 4.2 7.1e-08 32.2 4.2 5.5 6 1 1 7 7 6 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXL49986.1 - 1.9e-07 30.8 3.2 1.9e-07 30.8 3.2 4.6 4 1 0 4 4 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KXL49986.1 - 2.7e-07 30.4 0.5 2.7e-07 30.4 0.5 3.1 3 0 0 3 3 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 KXL49986.1 - 2.9e-06 27.2 4.9 2.9e-06 27.2 4.9 3.7 3 1 0 3 3 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KXL49986.1 - 3.6e-06 27.2 5.3 3.6e-06 27.2 5.3 4.9 4 1 0 4 4 3 1 Ring finger domain zf-RING_5 PF14634.6 KXL49986.1 - 3.9e-05 23.5 3.7 3.9e-05 23.5 3.7 5.4 6 0 0 6 6 5 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KXL49986.1 - 6e-05 23.1 5.3 6e-05 23.1 5.3 4.7 5 2 0 5 5 3 1 zinc finger of C3HC4-type, RING SH3_1 PF00018.28 KXL49986.1 - 7.9e-05 22.2 0.0 0.00022 20.7 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXL49986.1 - 0.0012 18.7 0.1 0.0012 18.7 0.1 2.1 2 0 0 2 2 2 1 Variant SH3 domain ZZ PF00569.17 KXL49986.1 - 0.0027 17.5 8.7 0.0027 17.5 8.7 4.1 4 0 0 4 4 4 2 Zinc finger, ZZ type SH3_2 PF07653.17 KXL49986.1 - 0.027 14.2 0.0 0.088 12.5 0.0 1.9 1 0 0 1 1 1 0 Variant SH3 domain Bowman-Birk_leg PF00228.20 KXL49986.1 - 8.2 6.9 10.3 0.7 10.4 3.7 2.8 2 0 0 2 2 2 0 Bowman-Birk serine protease inhibitor family CTP_synth_N PF06418.14 KXL49987.1 - 8.6e-119 395.7 0.1 1.1e-118 395.3 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KXL49987.1 - 7.3e-53 179.2 0.0 1.2e-52 178.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KXL49987.1 - 4.9e-06 26.4 0.3 0.00011 22.0 0.3 2.5 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 KXL49987.1 - 0.091 12.8 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Aldo_ket_red PF00248.21 KXL49988.1 - 3e-44 151.4 0.0 4.1e-44 150.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Whi5 PF08528.11 KXL49989.1 - 1.6e-08 34.0 0.1 2.9e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 Whi5 like SIMPL PF04402.14 KXL49989.1 - 0.013 16.0 0.4 0.026 15.0 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF541) Fungal_trans PF04082.18 KXL49990.1 - 2e-09 36.9 0.1 3.7e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL49990.1 - 1.5e-07 31.4 12.3 3.1e-07 30.4 12.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VirE_N PF08800.10 KXL49992.1 - 0.0096 16.0 0.0 0.01 16.0 0.0 1.1 1 0 0 1 1 1 1 VirE N-terminal domain SF3b10 PF07189.11 KXL49993.1 - 3.6e-36 123.1 0.0 4.2e-36 122.9 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) LMBR1 PF04791.16 KXL49994.1 - 4.9e-110 368.8 1.1 5.8e-110 368.6 1.1 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein Apolipoprotein PF01442.18 KXL49994.1 - 0.0016 18.4 0.6 0.0016 18.4 0.6 1.5 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain TFIIA_gamma_N PF02268.16 KXL49994.1 - 0.29 11.2 0.7 1.9 8.6 0.0 2.5 3 0 0 3 3 3 0 Transcription initiation factor IIA, gamma subunit, helical domain CEP209_CC5 PF16574.5 KXL49994.1 - 0.49 10.6 1.8 0.5 10.5 0.4 1.6 2 0 0 2 2 2 0 Coiled-coil region of centrosome protein CE290 DUF1644 PF07800.12 KXL49995.1 - 0.3 11.1 1.3 0.92 9.5 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1644) Lactonase PF10282.9 KXL49996.1 - 3.3e-17 62.8 15.1 5.4e-08 32.5 0.3 3.0 1 1 3 4 4 4 4 Lactonase, 7-bladed beta-propeller NHL PF01436.21 KXL49996.1 - 2.5e-07 30.4 2.1 0.42 10.7 0.1 5.1 5 0 0 5 5 5 2 NHL repeat Arylesterase PF01731.20 KXL49996.1 - 8.6e-05 22.7 9.9 0.054 13.7 0.6 3.6 2 1 0 3 3 3 2 Arylesterase Cytochrom_D1 PF02239.16 KXL49996.1 - 0.0003 19.4 1.5 0.1 11.1 0.2 2.2 1 1 1 2 2 2 2 Cytochrome D1 heme domain DUF4329 PF14220.6 KXL49996.1 - 0.00032 20.7 7.8 2.5 8.1 0.1 4.3 4 1 0 4 4 4 2 Domain of unknown function (DUF4329) DUF1416 PF07210.12 KXL49996.1 - 0.0021 17.9 0.6 12 5.9 0.0 4.1 3 1 0 4 4 4 0 Protein of unknown function (DUF1416) Glu_cyclase_2 PF05096.12 KXL49996.1 - 0.0028 17.1 0.0 1.4 8.3 0.0 2.4 1 1 1 2 2 2 2 Glutamine cyclotransferase DUF5627 PF18620.1 KXL49996.1 - 0.0048 16.8 7.1 7 6.5 0.3 4.7 2 2 2 5 5 5 1 Family of unknown function (DUF5627) PSII_BNR PF14870.6 KXL49996.1 - 0.0048 16.2 1.1 1 8.6 0.2 2.2 1 1 1 2 2 2 2 Photosynthesis system II assembly factor YCF48 SH2 PF00017.24 KXL49996.1 - 0.0075 16.3 0.3 11 6.2 0.0 4.3 1 1 4 5 5 5 1 SH2 domain Med13_N PF11597.8 KXL49996.1 - 0.055 12.9 1.2 0.63 9.4 0.1 2.7 1 1 1 3 3 3 0 Mediator complex subunit 13 N-terminal ART PF01129.18 KXL49996.1 - 0.063 12.6 2.3 2.8 7.2 0.1 2.8 1 1 2 3 3 3 0 NAD:arginine ADP-ribosyltransferase DUF5012 PF16404.5 KXL49996.1 - 0.081 13.0 4.4 0.16 12.1 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5012) Coa1 PF08695.10 KXL49996.1 - 0.25 11.1 3.1 2.9 7.7 0.0 2.9 3 0 0 3 3 3 0 Cytochrome oxidase complex assembly protein 1 FlaG PF03646.15 KXL49996.1 - 1.2 9.3 4.2 1.3e+02 2.8 0.1 3.7 4 0 0 4 4 4 0 FlaG protein MFS_1 PF07690.16 KXL49997.1 - 3.2e-13 49.3 39.3 2.1e-08 33.5 21.0 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily Arrestin_C PF02752.22 KXL49998.1 - 2.2e-14 54.1 0.0 6.4e-14 52.6 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain DASH_Dad3 PF08656.10 KXL50000.1 - 1.2e-22 79.7 0.7 2.8e-22 78.6 0.7 1.6 1 1 0 1 1 1 1 DASH complex subunit Dad3 Pkinase PF00069.25 KXL50001.1 - 5.8e-72 242.2 0.0 1.2e-71 241.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL50001.1 - 2.7e-30 105.5 0.0 7.8e-22 77.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KXL50001.1 - 6.5e-06 25.7 0.0 0.48 9.7 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Kdo PF06293.14 KXL50001.1 - 0.027 13.8 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXL50001.1 - 0.046 12.5 0.0 0.094 11.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KXL50001.1 - 0.073 13.0 0.0 1.8 8.4 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Rpr2 PF04032.16 KXL50002.1 - 5e-08 33.1 4.4 1.8e-07 31.3 4.2 2.1 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DDE_5 PF13546.6 KXL50002.1 - 0.013 14.9 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease zf-ribbon_3 PF13248.6 KXL50002.1 - 0.089 12.2 3.0 4.6 6.8 0.7 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_12 PF11331.8 KXL50002.1 - 1.2 9.0 3.5 0.93 9.4 0.3 2.2 2 0 0 2 2 2 0 Probable zinc-ribbon domain DBR1 PF05011.13 KXL50003.1 - 3.4e-37 128.0 0.1 4.6e-37 127.5 0.1 1.2 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 KXL50003.1 - 8.9e-07 29.6 0.5 1.8e-06 28.6 0.5 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase tRNA_int_end_N2 PF12928.7 KXL50004.1 - 1.2e-24 86.3 0.0 2.2e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 KXL50004.1 - 0.17 11.5 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain IU_nuc_hydro PF01156.19 KXL50006.1 - 0.029 13.9 0.0 0.03 13.9 0.0 1.1 1 0 0 1 1 1 0 Inosine-uridine preferring nucleoside hydrolase zf-ZPR1 PF03367.13 KXL50007.1 - 1.4e-113 376.0 0.0 5.2e-58 195.4 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zinc-ribbons_6 PF07191.12 KXL50007.1 - 0.31 11.0 3.3 2.1 8.4 0.5 2.4 2 0 0 2 2 2 0 zinc-ribbons zf_C2H2_10 PF18414.1 KXL50007.1 - 0.4 10.3 3.5 0.42 10.2 0.2 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger DUF4452 PF14618.6 KXL50009.1 - 4.2e-67 225.3 14.3 5.6e-67 224.8 14.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) Methyltransf_11 PF08241.12 KXL50011.1 - 8.5e-07 29.5 0.0 1.3e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL50011.1 - 1.9e-05 25.3 0.0 4.6e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL50011.1 - 9.8e-05 22.2 0.0 0.00013 21.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ribul_P_3_epim PF00834.19 KXL50011.1 - 0.056 12.8 0.2 0.11 11.8 0.1 1.5 2 0 0 2 2 2 0 Ribulose-phosphate 3 epimerase family Methyltransf_12 PF08242.12 KXL50011.1 - 0.1 13.4 0.0 0.17 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.16 KXL50012.1 - 1.7e-36 125.9 44.2 1.7e-36 125.9 44.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF364 PF04016.12 KXL50012.1 - 0.063 12.9 0.2 0.1 12.1 0.2 1.3 1 0 0 1 1 1 0 Putative heavy-metal chelation DPBB_1 PF03330.18 KXL50013.1 - 0.0039 17.4 0.1 0.015 15.6 0.1 2.1 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KXL50013.1 - 0.022 14.6 0.2 0.033 14.0 0.2 1.3 1 0 0 1 1 1 0 Barwin family DUF5349 PF17298.2 KXL50013.1 - 6.9 6.3 15.1 11 5.6 15.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5349) PC4 PF02229.16 KXL50015.1 - 2.8e-21 74.9 0.0 5.4e-21 74.0 0.0 1.5 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) MIP PF00230.20 KXL50016.1 - 1.4e-30 106.7 3.8 2e-30 106.2 3.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein adh_short_C2 PF13561.6 KXL50017.1 - 7.3e-40 137.0 0.2 9.9e-40 136.5 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL50017.1 - 3.3e-37 127.9 0.0 4.9e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL50017.1 - 2.8e-11 43.7 0.1 4.7e-11 42.9 0.1 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KXL50017.1 - 0.0072 15.8 0.0 0.078 12.4 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase SR-25 PF10500.9 KXL50020.1 - 0.0021 17.7 9.6 0.0024 17.5 9.6 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein RasGAP PF00616.19 KXL50021.1 - 3.6e-32 111.8 0.0 1e-28 100.5 0.0 2.9 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 KXL50021.1 - 0.00056 20.2 0.0 0.0083 16.4 0.0 2.6 2 1 0 2 2 2 1 C2 domain PH_17 PF18012.1 KXL50021.1 - 0.046 13.5 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 PH domain DTHCT PF08070.11 KXL50021.1 - 6.5 7.5 14.1 0.4 11.4 0.4 3.5 3 0 0 3 3 3 0 DTHCT (NUC029) region Sec1 PF00995.23 KXL50023.1 - 1.8e-103 347.8 0.0 2.1e-103 347.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family SUV3_C PF12513.8 KXL50024.1 - 2e-14 53.2 0.0 3.8e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 KXL50024.1 - 4.2e-10 40.0 0.1 7.7e-10 39.1 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 KXL50024.1 - 2e-06 27.6 0.1 4e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 DUF5585 PF17823.1 KXL50024.1 - 0.31 10.0 5.1 0.45 9.4 5.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5585) BPL_LplA_LipB_2 PF16917.5 KXL50025.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Biotin/lipoate A/B protein ligase family WD40 PF00400.32 KXL50026.1 - 7.3e-28 96.2 7.3 6.8e-06 26.7 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 KXL50026.1 - 6.7e-09 34.9 4.0 0.0074 15.0 0.1 4.1 3 1 1 4 4 4 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KXL50026.1 - 3.7e-06 27.1 0.0 4.3 7.7 0.0 4.6 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain DUF5046 PF16465.5 KXL50026.1 - 0.004 16.7 0.4 0.28 10.6 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF5046) BBS2_Mid PF14783.6 KXL50026.1 - 0.012 15.6 0.0 0.15 12.1 0.0 2.9 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region ATG16 PF08614.11 KXL50026.1 - 0.028 14.7 2.5 0.058 13.6 2.5 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4763 PF15960.5 KXL50026.1 - 0.23 10.7 1.9 0.35 10.1 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) CENP-F_leu_zip PF10473.9 KXL50026.1 - 0.27 11.3 8.6 0.43 10.6 8.6 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 KXL50026.1 - 0.3 11.6 7.9 0.8 10.2 7.9 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4164 PF13747.6 KXL50026.1 - 3.8 7.9 8.4 0.47 10.7 1.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) BCIP PF13862.6 KXL50027.1 - 2.2e-76 256.2 0.0 2.6e-76 256.0 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein RTP1_C1 PF10363.9 KXL50027.1 - 0.088 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 GATase PF00117.28 KXL50028.1 - 2.4e-40 138.3 0.0 4.1e-40 137.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 KXL50028.1 - 3.8e-36 123.0 0.0 8.7e-36 121.9 0.0 1.7 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.17 KXL50028.1 - 1.1e-10 41.0 0.2 7.6e-07 28.5 0.1 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 KXL50028.1 - 3.1e-07 30.4 0.1 6.4e-07 29.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.13 KXL50028.1 - 0.00016 21.3 0.0 0.00071 19.1 0.0 1.9 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KXL50028.1 - 0.00044 19.2 0.2 0.001 17.9 0.1 1.6 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.14 KXL50028.1 - 0.001 18.7 0.2 0.0034 17.0 0.0 2.0 3 0 0 3 3 3 1 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.19 KXL50028.1 - 0.014 14.7 0.1 0.023 14.0 0.1 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase ATP_bind_3 PF01171.20 KXL50028.1 - 0.08 12.7 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 PP-loop family sCache_like PF16736.5 KXL50028.1 - 0.2 11.8 0.2 0.42 10.7 0.2 1.6 1 0 0 1 1 1 0 Single Cache-like DIOX_N PF14226.6 KXL50029.1 - 1.7e-17 64.2 0.0 3e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXL50029.1 - 3.3e-16 59.6 0.0 6.6e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1214 PF06742.11 KXL50029.1 - 0.13 12.7 0.3 0.81 10.2 0.0 2.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1214) Rieske PF00355.26 KXL50030.1 - 9e-11 41.6 0.0 2.1e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 KXL50030.1 - 2.4e-09 37.5 0.2 6.1e-09 36.2 0.2 1.7 1 1 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Macro PF01661.21 KXL50031.1 - 3e-20 72.4 0.0 4.2e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 Macro domain RNase_P_Rpp14 PF01900.19 KXL50032.1 - 6.6e-37 125.9 0.0 8.9e-37 125.5 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family NUC153 PF08159.12 KXL50033.1 - 6e-14 51.5 15.5 2.8e-12 46.2 0.1 3.8 3 0 0 3 3 3 2 NUC153 domain CBFD_NFYB_HMF PF00808.23 KXL50034.1 - 1.7e-10 41.0 0.1 2.8e-10 40.3 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIIA PF03153.13 KXL50034.1 - 0.0074 16.3 5.8 0.0091 16.0 5.8 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Histone PF00125.24 KXL50034.1 - 0.018 15.4 0.1 0.018 15.4 0.1 1.9 2 1 0 2 2 2 0 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 KXL50034.1 - 0.05 13.7 0.0 0.098 12.8 0.0 1.4 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Voltage_CLC PF00654.20 KXL50035.1 - 1.9e-89 300.4 23.5 1.9e-89 300.4 23.5 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KXL50035.1 - 3.2e-10 40.3 0.0 0.00034 21.0 0.0 2.6 2 0 0 2 2 2 2 CBS domain Mlh1_C PF16413.5 KXL50036.1 - 3.4e-95 318.5 0.0 5.8e-95 317.7 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 KXL50036.1 - 3.8e-33 113.7 0.1 6.7e-33 112.9 0.1 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KXL50036.1 - 7.9e-11 41.9 0.0 1.7e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KXL50036.1 - 3.6e-07 30.7 0.0 1.1e-06 29.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CDC27 PF09507.10 KXL50038.1 - 1.6e-78 265.0 29.2 2.8e-78 264.2 29.2 1.4 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 TFCD_C PF12612.8 KXL50039.1 - 8.5e-15 55.1 1.4 9.5e-12 45.1 0.2 4.3 4 1 0 4 4 4 1 Tubulin folding cofactor D C terminal HEAT_EZ PF13513.6 KXL50039.1 - 6.7e-06 26.5 0.2 0.081 13.4 0.0 5.8 5 0 0 5 5 5 1 HEAT-like repeat HEAT_2 PF13646.6 KXL50039.1 - 0.00095 19.5 6.6 0.3 11.5 0.0 5.2 6 0 0 6 6 6 2 HEAT repeats HEAT PF02985.22 KXL50039.1 - 0.0083 16.3 15.7 0.071 13.4 0.0 6.6 8 0 0 8 8 8 2 HEAT repeat Cnd1 PF12717.7 KXL50039.1 - 0.017 15.2 0.0 0.33 11.0 0.1 3.0 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KXL50039.1 - 0.02 15.5 0.1 1.5 9.5 0.0 3.7 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region IFRD PF05004.13 KXL50039.1 - 0.059 12.5 0.0 0.53 9.3 0.0 2.4 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) MOR2-PAG1_N PF14222.6 KXL50040.1 - 1.4e-195 651.5 0.0 2.1e-195 650.9 0.0 1.3 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 KXL50040.1 - 4.4e-91 305.2 0.1 1.2e-90 303.8 0.1 1.8 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 KXL50040.1 - 6.4e-32 110.2 9.0 6e-13 47.4 0.0 4.2 2 1 1 3 3 3 3 Cell morphogenesis central region Helicase_IV_N PF12462.8 KXL50040.1 - 0.025 14.5 0.6 1.5 8.7 0.2 2.7 2 0 0 2 2 2 0 DNA helicase IV / RNA helicase N terminal HEAT PF02985.22 KXL50040.1 - 0.2 12.0 0.8 44 4.7 0.0 4.7 4 0 0 4 4 4 0 HEAT repeat RRM_1 PF00076.22 KXL50041.1 - 4.2e-27 93.8 0.0 3.3e-13 49.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ETC_C1_NDUFA4 PF04800.12 KXL50045.1 - 1.5e-35 121.3 1.7 2.1e-35 120.8 1.7 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region F1F0-ATPsyn_F PF10791.9 KXL50046.1 - 5e-38 129.5 0.1 5.6e-38 129.3 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 KXL50046.1 - 0.0046 17.3 0.1 0.0064 16.8 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f Phage_holin_2_1 PF04971.12 KXL50046.1 - 0.069 13.2 0.1 0.098 12.7 0.1 1.3 1 0 0 1 1 1 0 Bacteriophage P21 holin S Ammonium_transp PF00909.21 KXL50047.1 - 1.1e-105 353.6 22.0 1.3e-105 353.4 22.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family FAD_binding_1 PF00667.20 KXL50048.1 - 7.1e-67 225.2 0.0 1.1e-66 224.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KXL50048.1 - 4.4e-34 117.8 0.9 9.1e-34 116.7 0.9 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KXL50048.1 - 5.5e-21 75.3 0.1 4.3e-20 72.4 0.1 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Pex14_N PF04695.13 KXL50049.1 - 0.055 14.1 0.5 0.055 14.1 0.5 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pyridox_oxase_2 PF12766.7 KXL50050.1 - 1.5e-22 80.1 0.0 2.5e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase RIO1 PF01163.22 KXL50051.1 - 2e-41 141.7 0.0 2.9e-41 141.1 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 KXL50051.1 - 1.1e-31 108.9 0.0 2.8e-31 107.6 0.0 1.7 1 0 0 1 1 1 1 Rio2, N-terminal Kdo PF06293.14 KXL50051.1 - 8.2e-07 28.6 0.0 0.01 15.2 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXL50051.1 - 6.4e-06 26.3 0.3 0.045 13.7 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family RPN1_RPN2_N PF17781.1 KXL50052.1 - 4.7e-120 400.7 5.0 7.1e-120 400.1 5.0 1.3 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KXL50052.1 - 7e-25 86.8 0.0 1.3e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KXL50052.1 - 1.3e-18 66.4 18.8 4e-07 30.1 0.4 8.6 8 1 0 8 8 8 3 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KXL50052.1 - 9.7e-07 29.1 1.9 0.029 14.7 0.0 4.3 4 1 1 5 5 5 3 HEAT repeats zf-C2H2 PF00096.26 KXL50053.1 - 3.3e-09 36.7 25.0 4.8e-05 23.6 3.9 3.6 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXL50053.1 - 8.9e-08 32.3 20.1 0.0025 18.5 2.7 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXL50053.1 - 7.5e-05 23.0 16.9 0.003 17.9 1.4 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KXL50053.1 - 0.001 19.3 9.7 0.53 10.6 1.5 3.6 2 1 1 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KXL50053.1 - 0.0019 18.2 0.8 0.0019 18.2 0.8 3.0 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2HE PF16278.5 KXL50053.1 - 0.022 15.2 1.5 0.022 15.2 1.5 2.2 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger BBP1_N PF15271.6 KXL50053.1 - 0.026 15.3 0.2 0.037 14.8 0.2 1.5 1 1 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein zf-met PF12874.7 KXL50053.1 - 0.052 14.0 5.0 11 6.5 0.0 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zinc_ribbon_9 PF14369.6 KXL50053.1 - 0.18 12.1 6.8 0.48 10.7 0.3 3.1 3 0 0 3 3 3 0 zinc-ribbon zf_ZIC PF18366.1 KXL50053.1 - 0.53 10.4 4.9 0.72 10.0 0.3 2.6 1 1 1 2 2 2 0 Zic proteins zinc finger domain MCM_OB PF17207.3 KXL50053.1 - 0.64 9.9 3.4 0.78 9.6 3.4 1.2 1 0 0 1 1 1 0 MCM OB domain zf-CHCC PF10276.9 KXL50053.1 - 2.1 8.5 7.0 9.8 6.3 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger domain PI31_Prot_N PF11566.8 KXL50054.1 - 6.4e-44 149.6 0.0 8.3e-44 149.3 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 KXL50054.1 - 3.7e-13 50.4 15.1 3.7e-13 50.4 15.1 2.6 2 2 0 2 2 2 1 PI31 proteasome regulator tRNA_bind PF01588.20 KXL50055.1 - 2.8e-21 75.4 0.1 1.1e-20 73.5 0.0 2.1 2 1 0 2 2 2 1 Putative tRNA binding domain GST_C PF00043.25 KXL50055.1 - 0.00018 21.7 0.9 0.00051 20.2 0.0 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXL50055.1 - 0.001 19.1 0.0 0.0023 17.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KXL50055.1 - 0.023 14.5 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Pol_alpha_B_N PF08418.10 KXL50055.1 - 0.17 11.9 5.5 0.18 11.7 1.8 2.0 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal NUDIX PF00293.28 KXL50057.1 - 2.5e-27 95.5 0.0 3.7e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain MCM PF00493.23 KXL50058.1 - 2.9e-102 340.5 0.3 4.5e-102 339.9 0.3 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KXL50058.1 - 3.4e-40 136.8 0.6 8e-40 135.6 0.6 1.6 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 KXL50058.1 - 4.1e-30 104.2 2.4 8.4e-30 103.2 2.4 1.6 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 KXL50058.1 - 1.3e-23 83.2 0.1 3.7e-23 81.7 0.1 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KXL50058.1 - 1.3e-23 83.5 0.7 5e-23 81.7 0.7 2.1 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KXL50058.1 - 3.2e-08 33.2 0.0 9.1e-07 28.5 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KXL50058.1 - 0.00068 19.5 0.1 0.0043 16.9 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KXL50058.1 - 0.0018 18.0 0.0 0.0039 16.9 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 KXL50058.1 - 0.0071 16.3 0.0 0.022 14.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) adh_short PF00106.25 KXL50059.1 - 1.6e-54 184.3 0.4 2.1e-54 183.9 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL50059.1 - 1.1e-38 133.1 0.1 1.3e-38 132.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL50059.1 - 6.3e-14 52.3 0.1 9e-14 51.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KXL50059.1 - 0.0076 16.5 0.1 0.013 15.8 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain THF_DHG_CYH_C PF02882.19 KXL50059.1 - 0.021 14.1 2.4 1.1 8.5 0.0 3.1 3 1 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ADH_zinc_N PF00107.26 KXL50060.1 - 1.7e-25 89.5 0.0 2.7e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXL50060.1 - 2e-21 77.4 0.0 3.9e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXL50060.1 - 3.7e-07 30.0 0.0 7.5e-06 25.8 0.0 2.6 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain PA PF02225.22 KXL50060.1 - 0.013 15.5 0.0 0.029 14.4 0.0 1.7 1 1 0 1 1 1 0 PA domain ADH_N_2 PF16884.5 KXL50060.1 - 0.017 15.0 0.0 0.039 13.9 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase TrkA_N PF02254.18 KXL50060.1 - 0.048 13.9 0.0 0.093 13.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Arb1 PF09692.10 KXL50061.1 - 9.5e-101 337.9 0.0 1.2e-100 337.6 0.0 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 La PF05383.17 KXL50061.1 - 3e-16 59.2 0.0 6.7e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 La domain IPK PF03770.16 KXL50062.1 - 9.3e-53 179.0 0.0 1.1e-52 178.7 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase FDX-ACB PF03147.14 KXL50062.1 - 0.026 14.9 0.0 0.053 13.9 0.0 1.5 1 0 0 1 1 1 0 Ferredoxin-fold anticodon binding domain CoA_transf_3 PF02515.17 KXL50063.1 - 5.4e-105 351.5 0.0 6.1e-105 351.3 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III CLP1_P PF16575.5 KXL50064.1 - 1.7e-31 109.5 0.0 2.5e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 KXL50064.1 - 5.6e-28 97.0 0.0 9.4e-28 96.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 KXL50064.1 - 2.3e-24 86.0 0.0 3.8e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ATP_bind_1 PF03029.17 KXL50064.1 - 7e-05 22.7 0.0 0.00016 21.5 0.0 1.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 KXL50064.1 - 0.0021 18.2 0.0 0.015 15.4 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KXL50064.1 - 0.075 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 KXL50064.1 - 0.12 12.4 0.0 10 6.1 0.0 2.3 2 0 0 2 2 2 0 Dynamin family TniB PF05621.11 KXL50064.1 - 0.22 10.9 0.0 0.9 8.9 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein Malic_M PF03949.15 KXL50067.1 - 2.2e-91 305.7 0.0 3.1e-91 305.2 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KXL50067.1 - 9.6e-66 221.0 0.0 1.5e-65 220.4 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF4995 PF16386.5 KXL50068.1 - 0.05 13.6 0.2 1.7 8.7 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function Pex2_Pex12 PF04757.14 KXL50069.1 - 1.8e-34 119.3 1.9 2.8e-34 118.7 1.9 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 KXL50069.1 - 0.0097 16.0 3.8 0.02 15.1 3.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Nup54 PF13874.6 KXL50069.1 - 0.077 13.1 0.2 0.13 12.4 0.2 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 SNF2_N PF00176.23 KXL50070.1 - 2.3e-53 181.2 0.0 3.4e-53 180.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.6 KXL50070.1 - 4.7e-22 77.9 0.6 1.2e-21 76.6 0.6 1.7 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.31 KXL50070.1 - 5.7e-18 65.3 0.0 8.6e-16 58.3 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL50070.1 - 2e-07 31.2 0.0 9.1e-07 29.0 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KXL50070.1 - 3.3e-07 29.8 0.3 8.4e-07 28.4 0.3 1.7 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase EF-hand_like PF09279.11 KXL50070.1 - 0.39 11.2 2.0 0.46 11.0 0.3 2.0 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like RNase_PH PF01138.21 KXL50071.1 - 2.9e-37 128.1 0.2 5.4e-37 127.2 0.2 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 G-alpha PF00503.20 KXL50072.1 - 1.9e-122 408.8 2.1 2.2e-122 408.6 2.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KXL50072.1 - 3e-15 56.1 2.0 1.5e-10 40.8 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 KXL50072.1 - 0.00015 21.5 0.0 0.00069 19.4 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 KXL50072.1 - 0.0014 18.0 3.9 0.051 12.9 0.1 2.8 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region MCM PF00493.23 KXL50072.1 - 0.011 14.8 0.1 0.023 13.8 0.1 1.5 1 1 0 1 1 1 0 MCM P-loop domain Roc PF08477.13 KXL50072.1 - 0.017 15.4 0.4 2.6 8.3 0.0 2.7 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KXL50072.1 - 0.018 14.7 0.0 0.045 13.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KXL50072.1 - 0.08 13.4 0.5 0.15 12.6 0.1 1.8 1 1 1 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KXL50072.1 - 0.098 12.0 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family GTP_EFTU PF00009.27 KXL50072.1 - 0.1 12.1 0.1 1.8 8.1 0.1 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KXL50072.1 - 0.14 12.2 0.0 8.8 6.4 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase MIS13 PF08202.11 KXL50073.1 - 3.8e-47 161.1 0.4 7.5e-47 160.1 0.4 1.4 1 0 0 1 1 1 1 Mis12-Mtw1 protein family CorA PF01544.18 KXL50075.1 - 5.3e-05 22.7 2.6 0.00019 20.8 2.6 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein ApoLp-III PF07464.11 KXL50075.1 - 0.004 17.3 0.3 0.004 17.3 0.3 1.6 2 0 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) DUF2207 PF09972.9 KXL50075.1 - 0.044 12.5 1.6 0.31 9.7 1.6 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) PilJ PF13675.6 KXL50075.1 - 0.089 12.8 0.4 0.18 11.8 0.4 1.6 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term MAPEG PF01124.18 KXL50075.1 - 0.097 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 MAPEG family DivIVA PF05103.13 KXL50075.1 - 0.37 10.9 6.3 1.3 9.1 0.1 3.4 3 1 0 3 3 3 0 DivIVA protein SUN PF03856.13 KXL50076.1 - 2.9e-90 302.0 18.9 2.9e-90 302.0 18.9 1.5 2 0 0 2 2 2 1 Beta-glucosidase (SUN family) Kinesin PF00225.23 KXL50077.1 - 1.1e-115 386.1 0.2 2.7e-115 384.9 0.2 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXL50077.1 - 7.5e-29 100.6 0.1 2.8e-28 98.7 0.1 2.0 1 0 0 1 1 1 1 Microtubule binding MAD PF05557.13 KXL50077.1 - 0.62 8.4 48.6 0.081 11.3 17.1 2.9 3 0 0 3 3 3 0 Mitotic checkpoint protein DUF3349 PF11829.8 KXL50077.1 - 1.8 9.4 5.6 0.59 10.9 0.6 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) BTB PF00651.31 KXL50078.1 - 0.036 14.3 0.0 0.53 10.5 0.0 2.2 2 0 0 2 2 2 0 BTB/POZ domain NmrA PF05368.13 KXL50079.1 - 4.5e-16 59.1 0.0 6.7e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXL50079.1 - 4.8e-14 52.7 0.0 6.9e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXL50079.1 - 5.7e-07 29.9 0.1 8.9e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KXL50079.1 - 0.00036 20.1 0.1 0.00057 19.4 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.23 KXL50079.1 - 0.001 19.2 0.4 0.0019 18.3 0.4 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain ApbA PF02558.16 KXL50079.1 - 0.0019 17.9 0.1 0.0028 17.3 0.1 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 KXL50079.1 - 0.0022 18.0 0.1 0.0035 17.4 0.1 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 KXL50079.1 - 0.0039 17.6 0.2 0.0062 17.0 0.2 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KXL50079.1 - 0.0043 17.9 0.1 0.0067 17.3 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 KXL50079.1 - 0.012 15.8 0.3 0.02 15.0 0.3 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 KXL50079.1 - 0.02 13.9 0.1 0.046 12.7 0.1 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 KXL50079.1 - 0.049 14.2 0.3 0.083 13.5 0.3 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.24 KXL50079.1 - 0.089 12.4 0.2 1.7 8.1 0.2 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase PucR PF07905.11 KXL50079.1 - 0.16 12.3 0.0 0.37 11.1 0.0 1.6 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family AlaDh_PNT_C PF01262.21 KXL50079.1 - 0.18 11.1 0.7 0.28 10.4 0.7 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF4185 PF13810.6 KXL50080.1 - 5.5e-11 42.3 0.3 8.4e-11 41.7 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) Acetyltransf_3 PF13302.7 KXL50081.1 - 4e-14 53.5 0.0 5.3e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXL50081.1 - 1.3e-10 41.5 0.1 1.7e-10 41.1 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXL50081.1 - 2.5e-05 24.6 0.0 3.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KXL50081.1 - 0.0053 16.9 0.1 0.0084 16.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXL50081.1 - 0.038 13.9 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PIG-S PF10510.9 KXL50082.1 - 1.1e-141 473.2 0.0 1.2e-141 473.0 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Acyl-CoA_dh_1 PF00441.24 KXL50083.1 - 1.1e-40 139.3 1.9 1.7e-40 138.7 1.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXL50083.1 - 4.5e-22 78.1 0.2 7.7e-22 77.3 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 KXL50083.1 - 3.6e-20 71.9 0.2 7.6e-20 70.8 0.2 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 KXL50083.1 - 1.2e-15 58.1 0.0 2.8e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXL50083.1 - 9.2e-09 35.7 0.1 1.5e-08 34.9 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain p450 PF00067.22 KXL50084.1 - 2.8e-12 46.1 0.0 3e-12 46.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RRN9 PF10680.9 KXL50086.1 - 2.1e-16 60.0 1.5 5.6e-16 58.6 1.5 1.8 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor IF4E PF01652.18 KXL50087.1 - 6.3e-54 182.1 1.5 8e-54 181.7 1.5 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E MFS_1 PF07690.16 KXL50089.1 - 3.9e-17 62.2 58.9 2.2e-15 56.5 55.1 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXL50089.1 - 2.7e-13 49.2 24.5 5.3e-13 48.2 24.5 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Oxidored_q5_N PF01059.17 KXL50089.1 - 3.4 7.8 12.8 1.5 9.0 1.1 4.1 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus NUDIX PF00293.28 KXL50090.1 - 1.1e-06 28.7 0.6 1.9e-06 28.0 0.6 1.5 1 1 0 1 1 1 1 NUDIX domain Cas3_C PF18395.1 KXL50090.1 - 0.1 13.1 0.1 3.7 8.1 0.0 2.4 2 1 0 2 2 2 0 Cas3 C-terminal domain Sulfotransfer_4 PF17784.1 KXL50091.1 - 1.8e-26 93.3 0.7 9e-17 61.6 0.1 2.2 1 1 1 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXL50091.1 - 2.6e-05 24.7 4.9 0.006 17.0 1.9 2.3 1 1 1 2 2 2 2 Sulfotransferase family zf-H2C2_2 PF13465.6 KXL50092.1 - 0.065 13.7 1.6 4.3 7.9 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger double domain Herpes_LMP2 PF07415.11 KXL50092.1 - 0.25 10.1 1.9 0.35 9.6 1.9 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein AAA_10 PF12846.7 KXL50093.1 - 0.26 10.2 0.0 0.3 10.0 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain 2OG-FeII_Oxy_3 PF13640.6 KXL50096.1 - 8.8e-14 52.2 0.1 1.3e-13 51.6 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily EBP PF05241.12 KXL50097.1 - 0.066 12.7 3.3 0.15 11.5 1.8 2.0 2 0 0 2 2 2 0 Emopamil binding protein bZIP_1 PF00170.21 KXL50098.1 - 2e-07 31.0 7.2 2.8e-07 30.5 7.2 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXL50098.1 - 2.4e-05 24.3 12.5 3.3e-05 23.9 12.5 1.2 1 0 0 1 1 1 1 Basic region leucine zipper Herpes_UL56 PF04534.12 KXL50098.1 - 0.00082 18.9 0.6 0.0012 18.3 0.6 1.3 1 0 0 1 1 1 1 Herpesvirus UL56 protein bZIP_Maf PF03131.17 KXL50098.1 - 0.025 15.1 6.3 0.035 14.6 6.3 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor Fungal_trans PF04082.18 KXL50099.1 - 1.3e-28 99.8 0.0 2.4e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL50099.1 - 4.1e-10 39.6 13.0 7.2e-10 38.8 13.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glutaredoxin PF00462.24 KXL50100.1 - 3.9e-20 71.8 0.0 5.6e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 KXL50100.1 - 0.00061 20.2 0.1 0.0011 19.4 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 KXL50100.1 - 0.00089 19.6 0.0 0.0011 19.3 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) TraF PF13728.6 KXL50100.1 - 0.0038 17.1 0.0 0.0046 16.8 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 KXL50100.1 - 0.0044 17.0 0.0 0.0057 16.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain DSBA PF01323.20 KXL50100.1 - 0.0047 16.7 0.1 0.056 13.2 0.1 2.0 1 1 1 2 2 2 1 DSBA-like thioredoxin domain DUF1857 PF08982.11 KXL50101.1 - 2.7e-54 183.0 0.0 3.1e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) DSPc PF00782.20 KXL50104.1 - 1.1e-27 96.5 0.0 1.9e-27 95.7 0.0 1.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXL50104.1 - 0.0021 17.7 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Scs3p PF10261.9 KXL50105.1 - 6.2e-75 251.9 2.5 7.5e-75 251.6 2.5 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM FLILHELTA PF10306.9 KXL50105.1 - 0.13 12.7 0.1 0.63 10.5 0.0 2.1 2 0 0 2 2 2 0 Hypothetical protein FLILHELTA TPP_enzyme_N PF02776.18 KXL50106.1 - 1.5e-40 138.6 0.2 2.9e-40 137.7 0.2 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXL50106.1 - 1.3e-32 112.4 0.0 2.5e-32 111.5 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KXL50106.1 - 1.5e-20 73.5 0.4 6e-20 71.6 0.2 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain NMT1_3 PF16868.5 KXL50106.1 - 0.024 14.1 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 NMT1-like family EF-hand_1 PF00036.32 KXL50108.1 - 1.3e-41 137.0 12.9 8.2e-10 37.5 0.9 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KXL50108.1 - 4.1e-36 123.3 5.8 4.2e-19 68.8 2.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KXL50108.1 - 8.3e-35 118.4 11.4 2.5e-15 56.0 0.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KXL50108.1 - 8.6e-31 103.2 8.1 2e-09 36.6 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KXL50108.1 - 7.8e-26 88.4 10.6 2.7e-06 26.6 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KXL50108.1 - 1.7e-16 60.3 0.4 2.5e-09 37.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KXL50108.1 - 4.2e-09 36.3 2.3 0.0008 19.3 0.2 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KXL50108.1 - 6.4e-09 36.1 0.2 0.0017 18.7 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 KXL50108.1 - 1.1e-06 28.6 0.0 0.0082 16.2 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 KXL50108.1 - 6.1e-06 26.2 1.9 2.5e-05 24.3 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 KXL50108.1 - 0.0001 23.2 0.2 0.0028 18.5 0.1 2.1 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 KXL50108.1 - 0.00014 21.9 0.3 0.38 10.7 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB DUF3349 PF11829.8 KXL50108.1 - 0.0005 20.8 0.3 1.2 9.9 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Caleosin PF05042.13 KXL50108.1 - 0.0005 20.0 1.7 0.47 10.4 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 KXL50108.1 - 0.00064 20.0 0.8 0.58 10.5 0.2 2.7 2 1 0 2 2 2 2 RNA polymerase Rpb4 DUF5580 PF17743.1 KXL50108.1 - 0.0064 15.1 0.0 0.0066 15.1 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) Dockerin_1 PF00404.18 KXL50108.1 - 0.0064 16.7 7.0 0.4 10.9 0.8 2.9 1 1 2 3 3 3 2 Dockerin type I domain SurA_N_2 PF13623.6 KXL50108.1 - 0.01 15.7 0.9 0.34 10.7 0.1 2.3 1 1 1 2 2 2 0 SurA N-terminal domain EF-hand_14 PF17959.1 KXL50108.1 - 0.013 15.8 0.5 6.7 7.1 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain Poly_export PF02563.16 KXL50108.1 - 0.026 14.7 0.0 0.19 12.0 0.0 2.4 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein DUF4497 PF14924.6 KXL50108.1 - 0.032 14.7 0.0 9.4 6.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) RuvA_C PF07499.13 KXL50108.1 - 0.064 13.7 0.1 9 6.8 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain MotA_activ PF09114.10 KXL50108.1 - 0.065 13.4 0.2 1.3 9.2 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain dCache_2 PF08269.11 KXL50108.1 - 0.073 12.2 0.1 1.1 8.4 0.1 2.1 1 1 1 2 2 2 0 Cache domain RloB PF13707.6 KXL50108.1 - 0.16 12.1 1.2 0.9 9.7 0.2 2.0 1 1 1 2 2 2 0 RloB-like protein DUF5132 PF17195.4 KXL50108.1 - 0.16 12.0 0.5 21 5.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) SNARE PF05739.19 KXL50109.1 - 3e-15 55.9 0.3 7.7e-15 54.6 0.3 1.8 1 0 0 1 1 1 1 SNARE domain Sec2p PF06428.11 KXL50109.1 - 0.0098 15.8 0.4 0.0098 15.8 0.4 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Syntaxin PF00804.25 KXL50109.1 - 0.012 15.2 7.5 0.29 10.8 1.3 2.3 2 0 0 2 2 2 0 Syntaxin SlyX PF04102.12 KXL50109.1 - 3.7 8.2 7.7 0.28 11.8 0.4 2.8 3 1 0 3 3 3 0 SlyX Acetate_kinase PF00871.17 KXL50110.1 - 3.2e-73 246.7 0.0 3.8e-73 246.4 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family MitMem_reg PF13012.6 KXL50111.1 - 8.9e-14 51.9 1.3 6.7e-13 49.0 1.3 2.2 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KXL50111.1 - 1e-06 28.7 0.0 2.1e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease HalX PF08663.10 KXL50112.1 - 1.1 9.6 3.8 27 5.2 5.3 2.2 1 1 1 2 2 2 0 HalX domain GST_N PF02798.20 KXL50113.1 - 1.5e-11 44.5 0.1 3.7e-11 43.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXL50113.1 - 2.7e-08 34.1 0.0 6.9e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXL50113.1 - 3.3e-06 27.3 0.0 7.4e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXL50113.1 - 0.017 15.3 0.0 0.041 14.1 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXL50113.1 - 0.06 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Abhydrolase_1 PF00561.20 KXL50114.1 - 9.4e-47 159.8 0.0 2e-46 158.7 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXL50114.1 - 0.01 16.5 0.9 0.016 15.8 0.9 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 KXL50114.1 - 0.034 13.0 0.0 0.048 12.5 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 KXL50114.1 - 0.08 12.2 0.1 12 5.1 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KXL50114.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Lipase_GDSL PF00657.22 KXL50115.1 - 0.00072 19.6 0.0 0.00095 19.2 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Sec7 PF01369.20 KXL50116.1 - 1.1e-33 116.4 0.0 2.2e-33 115.5 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 KXL50116.1 - 3.8e-06 27.3 0.2 8.7e-06 26.1 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KXL50116.1 - 2.2e-05 24.9 0.0 5.5e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 PH domain Kinesin_assoc PF16183.5 KXL50116.1 - 0.032 14.4 0.1 0.12 12.6 0.1 1.9 1 0 0 1 1 1 0 Kinesin-associated Peptidase_M14 PF00246.24 KXL50117.1 - 3.4e-71 240.4 0.0 4.8e-71 239.9 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase SRP_TPR_like PF17004.5 KXL50118.1 - 6.3e-20 71.3 5.8 1.4e-19 70.2 3.3 2.4 2 0 0 2 2 2 1 Putative TPR-like repeat SRP72 PF08492.12 KXL50118.1 - 3.6e-17 62.5 11.3 3.6e-17 62.5 11.3 2.3 2 0 0 2 2 2 1 SRP72 RNA-binding domain ANAPC3 PF12895.7 KXL50118.1 - 2.9e-06 27.4 8.3 0.084 13.1 0.1 5.3 5 2 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KXL50118.1 - 0.00041 20.8 1.4 0.00041 20.8 1.4 6.5 4 2 2 6 6 6 1 Tetratricopeptide repeat DUF410 PF04190.13 KXL50118.1 - 0.017 15.0 2.6 0.086 12.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF410) TPR_9 PF13371.6 KXL50118.1 - 0.02 15.0 0.1 12 6.1 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXL50118.1 - 0.02 14.9 4.3 5.7 7.2 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXL50118.1 - 0.028 14.5 21.2 0.23 11.7 0.0 6.2 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXL50118.1 - 0.035 13.9 9.1 0.052 13.4 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat AF0941-like PF14591.6 KXL50118.1 - 0.054 14.1 2.2 0.19 12.3 0.2 2.4 2 0 0 2 2 2 0 AF0941-like 4HB_MCP_1 PF12729.7 KXL50118.1 - 0.13 11.8 0.1 0.13 11.8 0.1 2.3 3 0 0 3 3 3 0 Four helix bundle sensory module for signal transduction TPR_16 PF13432.6 KXL50118.1 - 0.4 11.4 16.1 2.4 8.9 0.1 4.6 5 1 1 6 6 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXL50118.1 - 0.73 10.2 8.4 3.6 7.9 0.1 4.9 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXL50118.1 - 0.77 10.7 21.3 22 6.2 0.1 7.1 6 3 3 9 9 7 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KXL50118.1 - 8.6 5.6 11.9 0.33 10.3 0.2 3.4 3 1 1 4 4 4 0 MalT-like TPR region Endonuclease_NS PF01223.23 KXL50119.1 - 6.8e-66 222.3 0.0 8.3e-66 222.0 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease YjbE PF11106.8 KXL50119.1 - 0.62 10.3 12.6 0.99 9.7 12.6 1.2 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE zf-Tim10_DDP PF02953.15 KXL50120.1 - 7.5e-22 76.7 0.4 9.5e-22 76.4 0.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Ribonuc_L-PSP PF01042.21 KXL50122.1 - 3.5e-40 136.8 0.1 3.8e-40 136.6 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Meth_synt_2 PF01717.18 KXL50122.1 - 0.024 13.9 0.0 0.024 13.9 0.0 1.1 1 0 0 1 1 1 0 Cobalamin-independent synthase, Catalytic domain Filament PF00038.21 KXL50123.1 - 1e-06 28.6 27.6 1e-06 28.6 27.6 10.1 2 2 7 9 9 9 2 Intermediate filament protein Nucleoside_tran PF01733.18 KXL50124.1 - 1.9e-43 149.0 10.2 2.1e-29 102.9 2.3 2.6 2 1 1 3 3 3 2 Nucleoside transporter MFS_1 PF07690.16 KXL50124.1 - 2.5e-05 23.4 32.6 0.0021 17.1 6.8 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily VIT1 PF01988.19 KXL50125.1 - 3.1e-63 213.5 4.9 3.9e-63 213.2 4.9 1.1 1 0 0 1 1 1 1 VIT family Phosphoesterase PF04185.14 KXL50126.1 - 3.5e-58 197.5 9.8 6e-58 196.7 9.8 1.4 1 1 0 1 1 1 1 Phosphoesterase family MraY_sig1 PF10555.9 KXL50126.1 - 0.05 13.1 0.2 0.11 12.1 0.2 1.6 1 0 0 1 1 1 0 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 Isochorismatase PF00857.20 KXL50127.1 - 3.6e-32 111.9 0.0 4.5e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family PAP_assoc PF03828.19 KXL50128.1 - 1.6e-15 57.0 0.2 3.7e-15 55.9 0.2 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KXL50128.1 - 4.3e-05 23.7 0.0 8.4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Apolipoprotein PF01442.18 KXL50128.1 - 0.041 13.7 5.3 0.24 11.3 0.1 2.4 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain FlxA PF14282.6 KXL50128.1 - 2.4 8.2 20.7 5.6 7.0 19.5 2.3 1 1 0 1 1 1 0 FlxA-like protein Isochorismatase PF00857.20 KXL50129.1 - 5.7e-11 42.9 0.0 7.7e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 Isochorismatase family Mito_carr PF00153.27 KXL50130.1 - 1.7e-70 233.0 1.0 5.3e-23 80.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DHFR_1 PF00186.19 KXL50131.1 - 1.3e-27 96.5 0.0 3.6e-21 75.5 0.0 2.2 2 0 0 2 2 2 2 Dihydrofolate reductase Raf1_HTH PF18579.1 KXL50131.1 - 0.0075 15.9 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Rubisco accumulation factor 1 helix turn helix domain Cpn60_TCP1 PF00118.24 KXL50134.1 - 1.1e-148 495.9 8.2 1.3e-148 495.7 8.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nitro_FeMo-Co PF02579.17 KXL50134.1 - 0.014 15.7 0.0 0.086 13.2 0.0 2.3 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor TetR_C_14 PF17754.1 KXL50134.1 - 0.76 9.7 6.9 0.2 11.6 1.2 2.5 2 0 0 2 2 2 0 MftR C-terminal domain Fez1 PF06818.15 KXL50135.1 - 0.035 14.5 0.0 0.06 13.8 0.0 1.3 1 0 0 1 1 1 0 Fez1 DIOX_N PF14226.6 KXL50136.1 - 2.5e-29 102.4 0.0 6.7e-29 101.0 0.0 1.7 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXL50136.1 - 2.3e-13 50.5 0.0 5.9e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ish1 PF10281.9 KXL50136.1 - 0.23 11.8 1.2 0.69 10.3 0.4 2.2 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein Autophagy_N PF03986.13 KXL50137.1 - 1.9e-42 144.4 0.0 3.1e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 KXL50137.1 - 1e-15 56.9 0.6 1e-15 56.9 0.6 2.1 2 0 0 2 2 2 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 KXL50137.1 - 3.5e-13 49.9 0.3 6.4e-13 49.1 0.3 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Sacchrp_dh_NADP PF03435.18 KXL50138.1 - 1.1e-13 51.6 0.0 1.6e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Ni_hydr_CYTB PF01292.20 KXL50138.1 - 0.059 13.0 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 Sacchrp_dh_C PF16653.5 KXL50138.1 - 0.085 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase C-terminal domain Ribosomal_L37ae PF01780.19 KXL50139.1 - 1.6e-43 146.7 9.5 1.8e-43 146.5 9.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 KXL50139.1 - 0.0021 18.2 1.7 0.0029 17.7 1.7 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-H2C2_2 PF13465.6 KXL50139.1 - 0.011 16.1 1.2 0.12 12.9 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger double domain Zn_Tnp_IS1595 PF12760.7 KXL50139.1 - 0.011 15.6 2.7 0.02 14.8 2.7 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Elf1 PF05129.13 KXL50139.1 - 0.013 15.5 1.7 0.021 14.8 1.7 1.4 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like DUF678 PF05077.12 KXL50139.1 - 0.024 14.7 1.2 0.032 14.3 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF678) zf-C4_ClpX PF06689.13 KXL50139.1 - 0.1 12.5 0.2 0.1 12.5 0.2 1.8 2 0 0 2 2 2 0 ClpX C4-type zinc finger C1_2 PF03107.16 KXL50139.1 - 0.11 12.8 2.9 0.77 10.1 3.0 1.9 1 1 1 2 2 2 0 C1 domain zf-BED PF02892.15 KXL50139.1 - 0.24 11.4 5.8 2.4 8.2 0.6 2.2 1 1 1 2 2 2 0 BED zinc finger PHD PF00628.29 KXL50140.1 - 2.2e-08 33.8 9.3 3.8e-08 33.1 9.3 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KXL50140.1 - 4e-05 23.1 4.3 7e-05 22.3 4.3 1.4 1 0 0 1 1 1 1 PHD-finger FYVE_2 PF02318.16 KXL50140.1 - 0.16 12.2 0.9 0.48 10.6 0.9 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger DZR PF12773.7 KXL50140.1 - 0.29 11.2 3.7 1.4 9.0 3.9 1.9 1 1 1 2 2 2 0 Double zinc ribbon C1_2 PF03107.16 KXL50140.1 - 7 7.0 8.3 1.5 9.2 3.7 2.0 2 0 0 2 2 2 0 C1 domain Med22 PF06179.12 KXL50142.1 - 5.1e-17 62.0 2.2 6.1e-17 61.8 2.2 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex GlutR_dimer PF00745.20 KXL50142.1 - 0.046 14.2 0.3 0.12 12.8 0.1 1.7 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain DAO PF01266.24 KXL50143.1 - 6.9e-36 124.6 0.7 8e-36 124.3 0.7 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXL50143.1 - 1.5e-05 25.5 1.8 0.0018 18.8 1.7 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXL50143.1 - 0.00028 20.2 0.9 0.00097 18.5 0.3 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXL50143.1 - 0.0048 17.1 1.2 0.012 15.8 1.2 1.7 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KXL50143.1 - 0.0063 15.8 0.8 0.013 14.7 0.8 1.5 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KXL50143.1 - 0.014 14.6 0.4 0.031 13.5 0.4 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.6 KXL50143.1 - 0.015 15.7 0.0 0.033 14.6 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 KXL50143.1 - 0.021 14.7 0.9 0.032 14.1 0.9 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KXL50143.1 - 0.037 13.3 0.1 0.091 12.0 0.1 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KXL50143.1 - 0.049 12.7 2.1 0.078 12.0 1.7 1.5 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 KXL50143.1 - 0.089 11.9 1.1 0.16 11.0 1.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KXL50143.1 - 0.16 11.2 0.2 0.82 8.9 0.3 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KXL50143.1 - 0.24 10.9 1.1 0.43 10.1 1.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Kinesin PF00225.23 KXL50144.1 - 5.4e-84 282.0 1.9 5.2e-46 157.1 4.3 2.6 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 KXL50144.1 - 1.5e-46 158.0 0.0 5.8e-46 156.1 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding ADIP PF11559.8 KXL50144.1 - 0.0042 17.2 8.0 0.0042 17.2 8.0 4.4 2 1 2 5 5 5 2 Afadin- and alpha -actinin-Binding Rootletin PF15035.6 KXL50144.1 - 0.0079 16.2 7.8 0.0079 16.2 7.8 3.6 2 1 2 4 4 3 1 Ciliary rootlet component, centrosome cohesion Filament PF00038.21 KXL50144.1 - 0.19 11.3 35.4 0.4 10.2 35.4 1.6 1 0 0 1 1 1 0 Intermediate filament protein DUF4472 PF14739.6 KXL50144.1 - 0.63 10.8 31.4 3.2 8.5 0.6 4.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4472) Spc7 PF08317.11 KXL50144.1 - 1.5 7.7 37.3 0.99 8.2 16.9 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 KXL50144.1 - 1.7 8.7 13.3 1.3 9.0 0.3 3.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.11 KXL50144.1 - 3.6 7.8 49.9 1.3 9.2 9.8 3.8 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Spectrin PF00435.21 KXL50144.1 - 3.6 8.1 31.3 0.088 13.3 5.7 4.5 1 1 3 4 4 4 0 Spectrin repeat YabA PF06156.13 KXL50144.1 - 4.8 7.9 22.4 4.1 8.1 4.0 4.8 3 1 1 4 4 4 0 Initiation control protein YabA BST2 PF16716.5 KXL50144.1 - 4.8 7.8 28.6 0.1 13.2 7.2 4.2 3 1 1 4 4 4 0 Bone marrow stromal antigen 2 Acyltransferase PF01553.21 KXL50145.1 - 0.0011 18.6 0.0 0.0067 16.0 0.0 2.0 1 1 0 1 1 1 1 Acyltransferase Ferric_reduct PF01794.19 KXL50146.1 - 7.2e-22 77.8 11.2 2e-21 76.4 10.9 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXL50146.1 - 9.5e-20 71.3 0.0 1.2e-12 48.2 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXL50146.1 - 1.3e-11 44.6 0.0 2.4e-10 40.5 0.0 2.2 1 1 0 1 1 1 1 FAD-binding domain SPW PF03779.14 KXL50147.1 - 0.042 13.4 0.2 0.054 13.1 0.2 1.2 1 0 0 1 1 1 0 SPW repeat ABC_tran PF00005.27 KXL50148.1 - 1.5e-07 32.0 0.0 1.8e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KXL50150.1 - 0.00094 18.9 0.3 0.001 18.8 0.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_membrane PF00664.23 KXL50152.1 - 8.7e-05 22.3 0.2 0.00012 21.8 0.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF1899 PF08953.11 KXL50153.1 - 8.3e-35 118.5 0.0 1.6e-34 117.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 KXL50153.1 - 1.1e-18 66.9 0.1 2.4e-18 65.8 0.1 1.6 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KXL50153.1 - 1.6e-14 54.1 10.9 8.9e-05 23.2 0.2 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL50153.1 - 1.9e-07 31.3 0.0 0.0019 18.4 0.1 3.9 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXL50153.1 - 0.024 13.3 0.2 0.57 8.8 0.1 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KXL50153.1 - 0.029 13.3 0.0 0.16 10.9 0.0 2.0 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ATG16 PF08614.11 KXL50153.1 - 0.041 14.1 3.0 0.06 13.6 3.0 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 KXL50153.1 - 0.31 11.7 2.8 0.68 10.6 0.5 2.2 2 0 0 2 2 2 0 SlyX Alpha_L_fucos PF01120.17 KXL50154.1 - 2.8e-80 270.4 7.1 3.8e-80 270.0 7.1 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase SE PF08491.10 KXL50155.1 - 7.8e-105 349.9 0.0 1e-104 349.5 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 KXL50155.1 - 4.6e-08 33.0 0.9 4.4e-05 23.2 0.6 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXL50155.1 - 9.4e-08 31.7 2.7 2.4e-06 27.1 2.7 2.3 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KXL50155.1 - 0.00021 20.5 0.0 0.00029 20.0 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KXL50155.1 - 0.00073 19.7 0.8 0.0015 18.7 0.8 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXL50155.1 - 0.0059 15.9 0.1 0.015 14.6 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KXL50155.1 - 0.0061 15.8 0.1 0.011 15.0 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXL50155.1 - 0.0063 15.6 2.3 0.01 15.0 2.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KXL50155.1 - 0.0072 16.9 0.2 0.018 15.6 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXL50155.1 - 0.0079 15.3 0.5 0.014 14.4 0.5 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein ApbA PF02558.16 KXL50155.1 - 0.013 15.1 0.2 0.023 14.4 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 KXL50155.1 - 0.022 14.8 0.1 0.039 14.0 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KXL50155.1 - 0.032 14.1 0.1 0.051 13.4 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 KXL50155.1 - 0.043 12.7 0.8 0.4 9.5 0.2 2.1 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 KXL50155.1 - 0.046 12.4 0.4 0.078 11.7 0.4 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 KXL50155.1 - 0.069 12.5 3.7 0.095 12.0 3.7 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.23 KXL50155.1 - 0.12 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ThiF PF00899.21 KXL50155.1 - 0.16 11.3 0.1 0.28 10.5 0.1 1.3 1 0 0 1 1 1 0 ThiF family Peptidase_M22 PF00814.25 KXL50159.1 - 6.2e-85 285.2 0.0 7.6e-85 284.9 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family MFS_2 PF13347.6 KXL50160.1 - 1.2e-08 34.0 12.4 5.8e-07 28.4 7.0 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein Na_H_Exchanger PF00999.21 KXL50161.1 - 4.5e-72 243.0 44.4 5.6e-72 242.6 44.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PepSY_TM PF03929.16 KXL50161.1 - 1.4 8.6 5.5 4.8 6.8 5.5 2.0 1 1 0 1 1 1 0 PepSY-associated TM region Sugar_tr PF00083.24 KXL50162.1 - 3.7e-104 349.1 20.2 4.4e-104 348.9 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL50162.1 - 9e-13 47.9 21.3 9e-13 47.9 21.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily AIRS PF00586.24 KXL50162.1 - 0.17 12.6 2.8 12 6.7 0.3 2.4 2 0 0 2 2 2 0 AIR synthase related protein, N-terminal domain AIRS_C PF02769.22 KXL50163.1 - 2e-32 112.5 0.0 3.5e-32 111.7 0.0 1.4 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 KXL50163.1 - 3.1e-15 56.6 1.1 9.3e-15 55.1 0.8 2.0 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain GHMP_kinases_N PF00288.26 KXL50163.1 - 7.7e-12 45.3 1.1 2.3e-11 43.7 0.1 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KXL50163.1 - 0.00011 22.6 0.1 0.00082 19.7 0.0 2.5 2 0 0 2 2 2 1 GHMP kinases C terminal Gcd10p PF04189.13 KXL50164.1 - 3.5e-111 371.1 0.0 4.3e-111 370.8 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family DUF1726 PF08351.11 KXL50164.1 - 0.015 15.2 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1726) DUF4127 PF13552.6 KXL50164.1 - 0.074 11.7 0.0 0.099 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4127) BRE1 PF08647.11 KXL50165.1 - 1.4e-24 86.0 9.4 1.4e-24 86.0 9.4 5.8 7 1 1 8 8 7 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.6 KXL50165.1 - 5.7e-09 35.7 7.2 9.1e-09 35.0 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXL50165.1 - 1.1e-08 34.8 7.1 1.7e-08 34.2 7.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXL50165.1 - 2.5e-07 30.5 8.9 3.9e-07 29.8 8.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXL50165.1 - 3.8e-07 30.3 7.6 6.3e-07 29.6 7.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KXL50165.1 - 7.6e-06 25.9 5.0 1.5e-05 24.9 5.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KXL50165.1 - 2.7e-05 23.9 7.0 4.7e-05 23.2 7.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXL50165.1 - 4.4e-05 23.4 8.0 7.6e-05 22.6 8.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Filament PF00038.21 KXL50165.1 - 0.00032 20.4 2.4 0.00032 20.4 2.4 5.7 3 2 1 4 4 3 1 Intermediate filament protein zf-C3HC4_4 PF15227.6 KXL50165.1 - 0.00068 19.7 7.4 0.0012 19.0 7.4 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KXL50165.1 - 0.0014 18.4 4.3 0.0029 17.3 4.3 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KXL50165.1 - 0.0092 16.3 4.6 0.02 15.2 4.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain HTH_IclR PF09339.10 KXL50165.1 - 0.019 14.8 0.2 0.048 13.5 0.2 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain zf-RING_6 PF14835.6 KXL50165.1 - 0.081 12.8 4.4 0.21 11.5 4.4 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Shugoshin_N PF07558.11 KXL50165.1 - 0.09 12.7 9.3 0.89 9.5 0.1 4.0 5 0 0 5 5 3 0 Shugoshin N-terminal coiled-coil region DZR PF12773.7 KXL50165.1 - 0.11 12.5 5.3 0.25 11.4 5.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-C3HC4_5 PF17121.5 KXL50165.1 - 0.17 11.8 7.1 0.4 10.6 7.1 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.6 KXL50165.1 - 0.27 10.7 4.4 0.9 9.0 1.5 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 KXL50165.1 - 0.31 11.1 3.3 0.73 9.9 3.3 1.6 1 0 0 1 1 1 0 zinc-ribbons zf-Nse PF11789.8 KXL50165.1 - 0.45 10.4 4.2 1.2 9.0 4.2 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TRAF_BIRC3_bd PF16673.5 KXL50165.1 - 0.5 10.2 17.4 3.1 7.7 0.3 5.5 5 2 0 5 5 4 0 TNF receptor-associated factor BIRC3 binding domain bZIP_1 PF00170.21 KXL50165.1 - 0.59 10.3 0.0 0.59 10.3 0.0 7.6 8 0 0 8 8 7 0 bZIP transcription factor HALZ PF02183.18 KXL50165.1 - 0.79 10.0 0.0 0.79 10.0 0.0 5.6 6 0 0 6 6 4 0 Homeobox associated leucine zipper Gluconate_2-dh3 PF13618.6 KXL50165.1 - 1 9.6 4.8 39 4.5 0.1 3.0 2 0 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 DUF5595 PF18077.1 KXL50165.1 - 1.7 8.7 11.0 19 5.4 0.0 5.0 4 1 1 5 5 4 0 Domain of unknown function (DUF5595) FYVE PF01363.21 KXL50165.1 - 3 8.0 8.8 26 5.1 8.9 2.2 1 1 0 1 1 1 0 FYVE zinc finger TSC22 PF01166.18 KXL50165.1 - 3.8 7.9 12.7 24 5.3 0.1 5.7 6 0 0 6 6 5 0 TSC-22/dip/bun family Baculo_PEP_C PF04513.12 KXL50165.1 - 6 6.9 15.2 0.2 11.7 3.4 3.5 4 1 0 4 4 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-Di19 PF05605.12 KXL50165.1 - 8.2 6.8 6.2 4.8 7.5 1.3 2.6 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Myb_DNA-bind_7 PF15963.5 KXL50166.1 - 2.4e-13 49.8 0.1 2.4e-13 49.8 0.1 2.1 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KXL50166.1 - 5.6e-08 32.9 1.3 1.2e-07 31.8 1.3 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXL50166.1 - 0.022 15.0 0.4 0.047 14.0 0.4 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Adeno_terminal PF02459.15 KXL50166.1 - 8.8 4.6 8.7 21 3.3 8.7 1.7 1 0 0 1 1 1 0 Adenoviral DNA terminal protein EPL1 PF10513.9 KXL50167.1 - 2.6e-27 96.1 1.3 2.6e-27 96.1 1.3 2.3 2 1 0 2 2 2 1 Enhancer of polycomb-like DUF2508 PF10704.9 KXL50167.1 - 0.17 12.1 2.7 0.34 11.1 1.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2508) SET PF00856.28 KXL50168.1 - 7.2e-19 68.8 0.0 1.4e-18 67.8 0.0 1.5 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 KXL50168.1 - 0.071 13.8 0.7 0.64 10.7 0.2 2.7 2 1 0 2 2 2 0 Rubisco LSMT substrate-binding tRNA-synt_1b PF00579.25 KXL50169.1 - 3.1e-73 246.6 0.0 4e-73 246.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF445 PF04286.12 KXL50169.1 - 0.0084 16.0 0.1 0.012 15.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF445) Cu_amine_oxid PF01179.20 KXL50170.1 - 3.8e-160 533.3 0.0 4.6e-160 533.0 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KXL50170.1 - 2e-21 76.3 0.2 7.5e-21 74.4 0.1 2.0 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KXL50170.1 - 5.1e-12 45.9 0.0 9.2e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain PLDc_2 PF13091.6 KXL50171.1 - 6.4e-18 64.9 0.0 1.2e-09 38.2 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KXL50171.1 - 1.5e-06 28.1 3.7 0.018 15.2 0.5 3.6 3 1 0 3 3 3 2 Phospholipase D Active site motif NDUFA12 PF05071.16 KXL50172.1 - 1.9e-29 102.3 4.7 2.4e-29 102.0 4.7 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 ABC_tran PF00005.27 KXL50173.1 - 5.7e-55 185.6 0.0 1.3e-30 106.7 0.0 2.9 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXL50173.1 - 2.2e-53 181.7 31.7 4.2e-33 115.2 10.3 3.6 4 0 0 4 4 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KXL50173.1 - 3.8e-09 36.3 0.1 0.066 12.6 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KXL50173.1 - 6.6e-09 36.0 0.0 0.0014 18.5 0.0 3.9 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KXL50173.1 - 7.5e-07 29.8 0.1 0.00077 20.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KXL50173.1 - 6.5e-06 26.2 0.3 0.05 13.7 0.0 3.6 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KXL50173.1 - 2.8e-05 24.4 0.4 1.7 8.9 0.0 3.5 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KXL50173.1 - 3.2e-05 23.9 0.1 0.11 12.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KXL50173.1 - 5.1e-05 23.7 0.0 0.42 11.0 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 KXL50173.1 - 0.00026 21.2 0.6 0.028 14.5 0.0 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_29 PF13555.6 KXL50173.1 - 0.00065 19.4 0.6 0.26 11.0 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain Dynamin_N PF00350.23 KXL50173.1 - 0.00089 19.3 0.9 1.3 9.1 0.1 3.6 3 0 0 3 3 3 1 Dynamin family T2SSE PF00437.20 KXL50173.1 - 0.0023 17.0 0.0 0.16 11.0 0.1 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 KXL50173.1 - 0.0059 16.3 0.0 4.2 7.1 0.0 2.9 2 0 0 2 2 2 1 IstB-like ATP binding protein CbiA PF01656.23 KXL50173.1 - 0.0061 16.6 0.9 0.11 12.5 0.0 3.4 5 0 0 5 5 4 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 KXL50173.1 - 0.012 15.2 0.2 2.2 7.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KXL50173.1 - 0.02 15.3 0.4 30 5.1 0.0 4.0 4 0 0 4 4 3 0 RNA helicase AAA PF00004.29 KXL50173.1 - 0.022 15.2 0.2 8.2 6.9 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KXL50173.1 - 0.023 14.4 0.2 0.2 11.3 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 KXL50173.1 - 0.03 14.5 0.0 5.5 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KXL50173.1 - 0.044 13.4 1.9 1.6 8.3 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KXL50173.1 - 0.047 13.4 0.6 7.8 6.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 KXL50173.1 - 0.05 13.4 0.2 46 3.7 0.0 3.3 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_7 PF12775.7 KXL50173.1 - 0.053 13.0 0.1 12 5.3 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 KXL50173.1 - 0.069 12.9 1.0 6.6 6.4 0.0 2.7 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.12 KXL50173.1 - 0.084 12.1 0.2 8.9 5.5 0.1 2.6 2 0 0 2 2 2 0 Zeta toxin TIP49 PF06068.13 KXL50173.1 - 0.096 11.9 0.2 1.3 8.2 0.0 2.1 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_18 PF13238.6 KXL50173.1 - 0.11 13.1 0.1 37 4.9 0.0 3.0 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KXL50173.1 - 0.13 11.7 0.3 7.3 6.0 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.15 KXL50173.1 - 0.14 12.2 0.1 23 4.9 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit CLP1_P PF16575.5 KXL50173.1 - 0.14 12.0 0.1 3 7.6 0.0 2.5 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop TrwB_AAD_bind PF10412.9 KXL50173.1 - 0.15 10.9 1.5 6.8 5.5 0.1 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.14 KXL50173.1 - 0.18 11.8 1.4 13 5.8 0.1 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 KXL50173.1 - 0.23 11.4 1.4 5.4 6.9 0.2 2.5 2 0 0 2 2 2 0 NACHT domain Roc PF08477.13 KXL50173.1 - 0.89 9.8 4.3 16 5.7 0.1 3.2 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase S_4TM PF18159.1 KXL50173.1 - 1.3 8.2 5.8 11 5.2 0.0 3.5 3 0 0 3 3 3 0 SMODS-associating 4TM effector domain Bacteriocin_IIc PF10439.9 KXL50174.1 - 0.033 14.3 1.6 0.078 13.1 1.3 1.6 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Ribosomal_S3Ae PF01015.18 KXL50175.1 - 3.5e-90 301.0 5.2 4.8e-90 300.5 5.2 1.2 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 KXL50175.1 - 0.11 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region NEMO PF11577.8 KXL50175.1 - 0.12 12.5 1.0 0.41 10.7 0.0 2.3 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Ham1p_like PF01725.16 KXL50176.1 - 5.6e-61 205.7 0.0 6.3e-61 205.6 0.0 1.0 1 0 0 1 1 1 1 Ham1 family AAA_18 PF13238.6 KXL50177.1 - 1.7e-28 99.8 0.8 5.1e-28 98.2 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KXL50177.1 - 4.1e-07 30.5 0.2 1.9e-06 28.4 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 KXL50177.1 - 0.0001 22.5 0.0 0.0042 17.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KXL50177.1 - 0.00012 22.3 0.0 0.0003 21.1 0.0 1.8 2 1 0 2 2 2 1 AAA domain dNK PF01712.19 KXL50177.1 - 0.00056 19.8 0.8 0.23 11.3 0.0 2.1 1 1 0 2 2 2 2 Deoxynucleoside kinase NTPase_1 PF03266.15 KXL50177.1 - 0.0016 18.4 0.1 0.0034 17.3 0.1 1.5 1 0 0 1 1 1 1 NTPase AAA_22 PF13401.6 KXL50177.1 - 0.002 18.4 0.0 0.0044 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain ADK PF00406.22 KXL50177.1 - 0.0031 17.6 0.4 0.033 14.3 0.0 2.1 1 1 1 2 2 2 1 Adenylate kinase AAA PF00004.29 KXL50177.1 - 0.0039 17.6 0.0 0.01 16.3 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.17 KXL50177.1 - 0.0045 16.7 0.1 1.8 8.2 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase AAA_16 PF13191.6 KXL50177.1 - 0.01 16.2 0.0 0.013 15.8 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.18 KXL50177.1 - 0.01 15.6 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SKI PF01202.22 KXL50177.1 - 0.012 15.8 0.0 0.18 11.9 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase ATP_bind_1 PF03029.17 KXL50177.1 - 0.019 14.8 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 KXL50177.1 - 0.022 14.5 0.0 0.055 13.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 KXL50177.1 - 0.025 14.0 0.0 0.052 13.0 0.0 1.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Colicin_Pyocin PF01320.18 KXL50177.1 - 0.03 14.4 0.4 0.057 13.5 0.4 1.5 1 0 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein Hydin_ADK PF17213.3 KXL50177.1 - 0.032 14.5 0.0 0.051 13.8 0.0 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Rad17 PF03215.15 KXL50177.1 - 0.047 13.6 0.0 0.086 12.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 KXL50177.1 - 0.07 13.2 0.1 0.15 12.2 0.1 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 KXL50177.1 - 0.093 13.1 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 KXL50177.1 - 0.096 12.7 0.0 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KXL50177.1 - 0.099 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 KXL50177.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation HTH_28 PF13518.6 KXL50177.1 - 0.13 12.4 0.0 4.9 7.4 0.0 2.5 3 0 0 3 3 2 0 Helix-turn-helix domain AAA_25 PF13481.6 KXL50177.1 - 0.16 11.5 0.0 2.2 7.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 KXL50177.1 - 0.16 10.9 0.4 0.99 8.3 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Abhydrolase_1 PF00561.20 KXL50178.1 - 9.3e-27 94.3 0.0 1.9e-24 86.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXL50178.1 - 8.5e-15 56.0 0.0 1.2e-14 55.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXL50178.1 - 3.5e-08 33.0 0.1 1.1e-07 31.4 0.1 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KXL50178.1 - 4.6e-07 30.2 0.0 6.1e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 KXL50178.1 - 6.5e-05 22.8 0.7 0.0042 16.8 0.7 2.1 1 1 0 1 1 1 1 PGAP1-like protein Chlorophyllase PF07224.11 KXL50178.1 - 0.00024 20.2 0.0 0.00044 19.4 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase Palm_thioest PF02089.15 KXL50178.1 - 0.00089 19.2 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 KXL50178.1 - 0.004 16.5 0.0 0.18 11.1 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Nipped-B_C PF12830.7 KXL50178.1 - 0.011 15.7 0.0 1 9.3 0.0 2.1 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus Chlorophyllase2 PF12740.7 KXL50178.1 - 0.017 14.0 0.0 0.032 13.2 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme LCAT PF02450.15 KXL50178.1 - 0.021 14.0 0.1 0.029 13.5 0.1 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase UPF0227 PF05728.12 KXL50178.1 - 0.025 14.5 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Esterase PF00756.20 KXL50178.1 - 0.074 12.7 0.1 0.13 11.9 0.1 1.5 1 1 0 1 1 1 0 Putative esterase Nitr_red_bet_C PF14711.6 KXL50178.1 - 0.091 12.5 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Respiratory nitrate reductase beta C-terminal DUF676 PF05057.14 KXL50178.1 - 0.091 12.3 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Ndr PF03096.14 KXL50178.1 - 0.18 10.5 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 Ndr family His_Phos_2 PF00328.22 KXL50179.1 - 8.8e-05 22.0 0.1 0.012 15.0 0.0 2.7 2 1 1 3 3 3 2 Histidine phosphatase superfamily (branch 2) BNR_2 PF13088.6 KXL50180.1 - 1.3e-17 64.0 2.0 5.5e-06 25.9 0.1 3.2 1 1 2 3 3 3 3 BNR repeat-like domain Sortilin-Vps10 PF15902.5 KXL50180.1 - 0.00019 20.3 0.2 0.0018 17.1 0.0 2.3 3 0 0 3 3 3 1 Sortilin, neurotensin receptor 3, DUF4185 PF13810.6 KXL50180.1 - 0.0016 17.7 2.4 0.0016 17.7 2.4 3.5 1 1 2 3 3 3 1 Domain of unknown function (DUF4185) PSII_BNR PF14870.6 KXL50180.1 - 0.0052 16.1 8.1 0.051 12.8 0.4 3.4 3 1 1 4 4 4 2 Photosynthesis system II assembly factor YCF48 CyRPA PF18638.1 KXL50180.1 - 0.017 14.3 2.3 14 4.7 0.0 3.3 3 1 0 4 4 4 0 Cysteine-Rich Protective Antigen 6 bladed domain BNR_4 PF15892.5 KXL50180.1 - 0.018 14.4 2.1 0.035 13.5 1.7 1.8 1 1 0 1 1 1 0 BNR repeat-containing family member BNR PF02012.20 KXL50180.1 - 0.021 14.7 30.5 0.26 11.4 0.9 5.9 5 0 0 5 5 5 0 BNR/Asp-box repeat Aldo_ket_red PF00248.21 KXL50181.1 - 3e-64 217.1 0.0 3.6e-64 216.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_transf_8 PF01501.20 KXL50182.1 - 1.4e-08 34.6 8.2 8.3e-08 32.1 8.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 Ribosomal_S10 PF00338.22 KXL50183.1 - 4.3e-21 75.0 0.0 8.2e-21 74.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e PNP_UDP_1 PF01048.20 KXL50184.1 - 1.4e-50 171.8 0.0 1.7e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Fcf2 PF08698.11 KXL50185.1 - 4.1e-36 123.3 2.1 5.6e-36 122.8 0.1 2.1 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing SNF2_N PF00176.23 KXL50187.1 - 2.5e-43 148.2 0.0 4.3e-43 147.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXL50187.1 - 1.2e-18 67.5 0.0 2.8e-18 66.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL50187.1 - 2.4e-05 24.4 0.0 0.00013 22.0 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 KXL50187.1 - 3.6e-05 23.6 0.2 0.017 14.8 0.0 2.4 2 0 0 2 2 2 2 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 KXL50187.1 - 0.00015 21.0 0.0 0.00029 20.2 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase GSH_synth_ATP PF03917.17 KXL50188.1 - 1.8e-140 468.0 0.0 2.1e-140 467.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KXL50188.1 - 2.8e-34 117.6 0.0 5.2e-34 116.8 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Forkhead PF00250.18 KXL50189.1 - 5.5e-36 122.7 0.2 9.1e-36 122.0 0.2 1.4 1 0 0 1 1 1 1 Forkhead domain adh_short PF00106.25 KXL50190.1 - 1.6e-22 80.0 0.0 2.3e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL50190.1 - 4.1e-18 65.8 0.0 5.9e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL50190.1 - 0.0014 18.6 0.0 0.0027 17.6 0.0 1.4 1 1 0 1 1 1 1 KR domain MMM1 PF10296.9 KXL50191.1 - 2.8e-135 450.6 0.0 3.7e-135 450.2 0.0 1.1 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 ProSAAS PF07259.12 KXL50191.1 - 4.2 7.3 8.5 0.23 11.4 1.9 2.0 2 0 0 2 2 2 0 ProSAAS precursor DNA_binding_1 PF01035.20 KXL50193.1 - 2e-23 82.3 0.0 2.6e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain BAR PF03114.18 KXL50194.1 - 2.5e-63 213.9 3.4 2.8e-63 213.8 3.4 1.0 1 0 0 1 1 1 1 BAR domain CP12 PF02672.15 KXL50194.1 - 0.00078 20.1 0.1 0.0064 17.2 0.0 2.4 2 0 0 2 2 2 1 CP12 domain Arfaptin PF06456.13 KXL50194.1 - 0.0054 16.3 3.6 0.019 14.6 3.6 1.9 1 1 0 1 1 1 1 Arfaptin-like domain SVIP PF15811.5 KXL50194.1 - 3.1 8.3 6.6 0.24 11.9 0.8 2.1 3 0 0 3 3 3 0 Small VCP/p97-interacting protein HALZ PF02183.18 KXL50194.1 - 3.2 8.1 6.5 1.5 9.1 0.2 3.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF3782 PF12644.7 KXL50196.1 - 0.069 13.3 0.1 0.2 11.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) CLZ PF16526.5 KXL50196.1 - 0.08 13.3 6.2 0.39 11.1 2.1 2.9 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Baculo_PEP_C PF04513.12 KXL50196.1 - 0.39 10.8 3.1 2.9 7.9 0.9 2.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus PspB PF06667.12 KXL50196.1 - 8.6 6.5 6.6 2.1 8.4 0.0 3.0 3 1 0 3 3 3 0 Phage shock protein B TPR_12 PF13424.6 KXL50197.1 - 1.1e-13 51.2 11.4 2.1e-06 28.0 0.1 6.2 3 1 4 7 7 7 4 Tetratricopeptide repeat NB-ARC PF00931.22 KXL50197.1 - 2.6e-08 33.4 0.0 2.7e-07 30.1 0.0 2.2 1 1 0 1 1 1 1 NB-ARC domain TPR_10 PF13374.6 KXL50197.1 - 4.9e-07 29.4 15.1 0.0082 16.0 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXL50197.1 - 1.7e-06 27.6 1.1 0.036 13.9 0.0 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXL50197.1 - 5.5e-06 26.1 9.4 0.087 13.0 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 KXL50197.1 - 0.00044 20.6 2.0 1.8 9.5 0.0 3.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXL50197.1 - 0.0063 16.6 2.0 6.9 7.2 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF3856 PF12968.7 KXL50197.1 - 0.0067 16.5 0.2 0.027 14.5 0.1 2.0 2 0 0 2 2 2 1 Domain of Unknown Function (DUF3856) AAA_16 PF13191.6 KXL50197.1 - 0.0075 16.7 0.0 0.034 14.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 KXL50197.1 - 0.013 15.5 0.0 0.046 13.6 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TPR_19 PF14559.6 KXL50197.1 - 0.051 14.1 1.5 2 9.0 0.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat AAA_22 PF13401.6 KXL50197.1 - 0.11 12.8 0.0 0.39 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain TPR_7 PF13176.6 KXL50197.1 - 0.13 12.3 0.2 37 4.7 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat BSP_II PF05432.11 KXL50199.1 - 0.0012 18.6 15.9 0.0015 18.3 15.9 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) PBP1_TM PF14812.6 KXL50199.1 - 0.0019 18.6 4.7 0.0022 18.3 4.7 1.1 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 KXL50199.1 - 0.0071 16.0 5.7 0.0091 15.7 5.7 1.2 1 0 0 1 1 1 1 FAM176 family FYDLN_acid PF09538.10 KXL50199.1 - 0.02 15.6 5.5 0.024 15.3 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Pox_Ag35 PF03286.14 KXL50199.1 - 0.022 14.6 8.2 0.024 14.4 8.2 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RPN2_C PF18004.1 KXL50199.1 - 0.025 14.5 8.0 0.029 14.3 8.0 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Pinin_SDK_memA PF04696.13 KXL50199.1 - 0.034 14.2 10.7 0.039 14.0 10.7 1.1 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region DUF913 PF06025.12 KXL50199.1 - 0.04 12.9 1.3 0.039 12.9 1.3 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF5523 PF17661.1 KXL50199.1 - 0.043 13.5 11.3 0.049 13.3 11.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5523) PEX11 PF05648.14 KXL50199.1 - 0.047 13.2 0.4 0.052 13.0 0.4 1.1 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Tim54 PF11711.8 KXL50199.1 - 0.05 12.4 5.1 0.05 12.4 5.1 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Antimicrobial_8 PF08103.11 KXL50199.1 - 0.054 13.6 0.4 0.29 11.3 0.4 1.9 2 0 0 2 2 2 0 Uperin family EIIBC-GUT_N PF03612.14 KXL50199.1 - 0.066 13.0 2.0 0.077 12.7 2.0 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus TRAP_alpha PF03896.16 KXL50199.1 - 0.089 12.0 3.3 0.096 11.9 3.3 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2428 PF10350.9 KXL50199.1 - 0.091 12.0 0.4 0.099 11.9 0.4 1.0 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) Afi1 PF07792.12 KXL50199.1 - 0.11 13.0 3.8 0.12 12.8 3.8 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF4820 PF16091.5 KXL50199.1 - 0.11 11.8 5.3 0.13 11.6 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Connexin PF00029.19 KXL50199.1 - 0.14 11.9 2.5 0.15 11.8 2.5 1.1 1 0 0 1 1 1 0 Connexin Vfa1 PF08432.10 KXL50199.1 - 0.16 12.3 7.7 0.18 12.2 7.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Usp PF00582.26 KXL50199.1 - 0.18 12.3 3.5 0.22 12.0 3.5 1.1 1 0 0 1 1 1 0 Universal stress protein family RRN3 PF05327.11 KXL50199.1 - 0.29 9.6 2.5 0.26 9.8 2.5 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4746 PF15928.5 KXL50199.1 - 0.37 10.2 10.2 0.36 10.2 10.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RNA_pol_Rpc4 PF05132.14 KXL50199.1 - 0.44 11.0 5.3 0.47 10.9 5.3 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Presenilin PF01080.17 KXL50199.1 - 0.54 9.0 3.5 0.55 8.9 3.5 1.1 1 0 0 1 1 1 0 Presenilin Nucleo_P87 PF07267.11 KXL50199.1 - 0.6 8.9 7.5 0.68 8.7 7.5 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Myc_N PF01056.18 KXL50199.1 - 0.71 9.7 8.2 0.79 9.6 8.2 1.1 1 0 0 1 1 1 0 Myc amino-terminal region DNA_pol_phi PF04931.13 KXL50199.1 - 0.92 7.5 11.8 0.96 7.5 11.8 1.0 1 0 0 1 1 1 0 DNA polymerase phi V_ATPase_I PF01496.19 KXL50199.1 - 0.96 7.3 3.2 0.99 7.2 3.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OATP PF03137.20 KXL50199.1 - 1.1 7.4 2.3 1.2 7.3 2.3 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CENP-B_dimeris PF09026.10 KXL50199.1 - 1.2 9.6 7.9 1.5 9.2 7.9 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF3464 PF11947.8 KXL50199.1 - 1.3 8.7 5.0 1.5 8.6 5.0 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Adeno_terminal PF02459.15 KXL50199.1 - 1.6 7.0 8.2 1.7 6.9 8.2 1.0 1 0 0 1 1 1 0 Adenoviral DNA terminal protein TFB6 PF17110.5 KXL50199.1 - 2 8.2 6.1 2.3 7.9 6.1 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH GOLD_2 PF13897.6 KXL50199.1 - 2.3 8.7 6.0 2.7 8.5 6.0 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking ORC_WH_C PF18137.1 KXL50199.1 - 2.7 8.1 8.7 3.3 7.8 8.7 1.1 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal DUF4637 PF15470.6 KXL50199.1 - 3.2 7.5 13.0 3.9 7.2 13.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CobT PF06213.12 KXL50199.1 - 3.3 7.0 14.2 3.8 6.8 14.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Cytomega_UL84 PF06284.11 KXL50199.1 - 3.3 6.0 7.7 3.3 6.0 7.7 1.0 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein NOA36 PF06524.12 KXL50199.1 - 3.9 6.7 11.7 4.5 6.5 11.7 1.1 1 0 0 1 1 1 0 NOA36 protein MscS_TM PF12794.7 KXL50199.1 - 4.1 6.2 6.6 4.5 6.0 6.6 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 MAP17 PF15807.5 KXL50199.1 - 5.9 7.1 7.6 7.5 6.8 7.6 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 CDC45 PF02724.14 KXL50199.1 - 6.7 4.9 12.0 7.5 4.7 12.0 1.0 1 0 0 1 1 1 0 CDC45-like protein rve PF00665.26 KXL50201.1 - 0.046 13.9 0.0 0.046 13.9 0.0 1.1 1 0 0 1 1 1 0 Integrase core domain Integrase_H2C2 PF17921.1 KXL50202.1 - 4.9e-05 23.4 0.1 7.9e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain WD40 PF00400.32 KXL50203.1 - 7.5e-59 194.3 32.0 2e-10 41.1 0.4 9.0 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL50203.1 - 2e-22 79.3 1.4 0.00017 21.8 0.0 5.1 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXL50203.1 - 2e-07 30.0 1.2 0.24 10.0 0.1 5.2 5 1 0 6 6 6 2 Nucleoporin Nup120/160 FAD_binding_9 PF08021.11 KXL50203.1 - 5.3e-06 26.7 0.0 0.12 12.6 0.0 2.5 2 0 0 2 2 2 2 Siderophore-interacting FAD-binding domain eIF2A PF08662.11 KXL50203.1 - 1.2e-05 25.3 0.0 0.028 14.3 0.0 3.5 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KXL50203.1 - 1.9e-05 23.8 0.3 0.072 12.0 0.0 4.1 3 2 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein NLE PF08154.12 KXL50203.1 - 0.0032 18.0 0.0 0.0063 17.0 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nbas_N PF15492.6 KXL50203.1 - 0.023 14.1 0.1 1.2 8.5 0.0 2.9 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.11 KXL50203.1 - 0.046 12.5 0.0 0.33 9.7 0.0 2.3 1 1 1 2 2 2 0 Nup133 N terminal like CMAS PF02353.20 KXL50204.1 - 1.2e-63 215.0 0.2 1.5e-63 214.7 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KXL50204.1 - 4.5e-09 36.4 0.0 8e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL50204.1 - 3.5e-08 34.0 0.0 7e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL50204.1 - 2e-07 31.6 0.0 4.1e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXL50204.1 - 0.06 13.1 0.0 0.092 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KXL50204.1 - 0.13 11.8 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 KXL50204.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Lipase_3 PF01764.25 KXL50205.1 - 1.4e-28 99.6 0.0 2.2e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KXL50205.1 - 0.00016 22.4 6.1 0.00016 22.4 6.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 KXL50205.1 - 0.0064 16.0 0.0 0.0091 15.5 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KXL50205.1 - 0.026 13.8 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXL50205.1 - 0.039 13.6 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold UPF0227 PF05728.12 KXL50205.1 - 0.25 11.3 0.0 0.39 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PLA2_B PF01735.18 KXL50206.1 - 6e-107 358.1 0.0 7.2e-107 357.8 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain INSIG PF07281.12 KXL50208.1 - 1.3e-70 237.4 0.2 1.6e-70 237.1 0.2 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) WD40 PF00400.32 KXL50209.1 - 9.6e-24 83.2 20.9 4e-07 30.6 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.12 KXL50209.1 - 9.3e-19 67.7 0.5 1.7e-18 66.9 0.5 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 KXL50209.1 - 3.1e-05 22.8 1.4 0.00034 19.4 0.6 2.4 2 0 0 2 2 2 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KXL50209.1 - 0.0016 18.7 0.1 3.8 7.9 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1513 PF07433.11 KXL50209.1 - 0.016 14.3 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) NAD_binding_10 PF13460.6 KXL50210.1 - 2.2e-17 63.6 0.0 5.3e-17 62.3 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KXL50210.1 - 2e-08 34.0 0.0 2.8e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KXL50210.1 - 0.00027 20.6 0.0 0.00038 20.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 KXL50210.1 - 0.00032 19.9 0.0 0.00046 19.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KXL50210.1 - 0.0004 19.6 0.0 0.00054 19.2 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KXL50210.1 - 0.00053 19.5 0.0 0.00074 19.0 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 KXL50210.1 - 0.0029 17.9 0.0 0.0049 17.1 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.17 KXL50210.1 - 0.011 16.3 0.0 0.027 15.1 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 KXL50210.1 - 0.062 13.7 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain CbiJ PF02571.14 KXL50210.1 - 0.093 12.2 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK adh_short PF00106.25 KXL50211.1 - 2.5e-33 115.2 0.1 3.3e-33 114.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL50211.1 - 3e-25 89.1 0.3 4.2e-25 88.7 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL50211.1 - 0.00023 21.2 0.8 0.0011 18.9 0.8 1.9 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KXL50211.1 - 0.0065 16.4 0.2 0.34 10.8 0.0 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KXL50211.1 - 0.0066 15.5 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family HEM4 PF02602.15 KXL50211.1 - 0.12 11.7 0.0 15 4.9 0.0 2.3 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD Aa_trans PF01490.18 KXL50212.1 - 4.5e-82 275.9 33.7 5.3e-82 275.7 33.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KXL50212.1 - 3.6e-05 23.0 15.4 3.6e-05 23.0 15.4 1.9 1 1 0 2 2 2 1 Tryptophan/tyrosine permease family EIAV_Rev PF11129.8 KXL50212.1 - 0.065 13.4 0.2 0.13 12.5 0.2 1.4 1 0 0 1 1 1 0 Rev protein of equine infectious anaemia virus Ank_2 PF12796.7 KXL50213.1 - 5.4e-45 151.9 7.6 4.3e-09 36.8 0.1 6.9 5 1 2 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXL50213.1 - 3.5e-35 119.9 12.3 6e-06 26.7 0.1 10.6 7 3 5 12 12 12 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXL50213.1 - 3e-30 100.9 10.5 0.00038 20.7 0.0 12.9 13 0 0 13 13 13 8 Ankyrin repeat Ank_5 PF13857.6 KXL50213.1 - 1.8e-28 98.2 13.3 5.7e-05 23.3 0.0 10.4 7 3 5 12 12 12 8 Ankyrin repeats (many copies) Ank PF00023.30 KXL50213.1 - 4.2e-22 77.5 20.7 0.012 16.1 0.0 13.5 14 1 0 14 14 14 6 Ankyrin repeat MutS_V PF00488.21 KXL50214.1 - 3.8e-72 242.3 0.1 7.9e-72 241.2 0.1 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXL50214.1 - 8.1e-34 117.5 1.0 8.1e-34 117.5 1.0 2.6 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 KXL50214.1 - 1e-29 103.1 0.0 2.9e-29 101.6 0.0 1.9 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KXL50214.1 - 2.4e-09 37.6 2.2 2.6e-09 37.4 0.1 2.2 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 KXL50214.1 - 0.0011 19.3 0.1 0.0037 17.6 0.1 2.0 1 0 0 1 1 1 1 MutS family domain IV DUF4911 PF16256.5 KXL50214.1 - 0.005 16.8 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4911) GRP PF07172.11 KXL50215.1 - 1.2 9.8 19.7 1.9 9.2 19.7 1.3 1 0 0 1 1 1 0 Glycine rich protein family HEAT PF02985.22 KXL50216.1 - 0.85 10.0 3.5 0.98 9.9 0.0 2.9 3 0 0 3 3 3 0 HEAT repeat Peptidase_C14 PF00656.22 KXL50217.1 - 1.4e-43 149.7 0.0 1.8e-43 149.3 0.0 1.1 1 0 0 1 1 1 1 Caspase domain FGGY_C PF02782.16 KXL50218.1 - 5.6e-72 241.6 1.3 1.8e-71 240.0 0.9 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KXL50218.1 - 6.7e-62 209.2 0.0 1.1e-61 208.5 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain MIP PF00230.20 KXL50219.1 - 7.2e-56 189.4 4.0 9.5e-56 189.0 4.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein Phage_holin_5_2 PF16079.5 KXL50219.1 - 0.51 10.7 3.6 4 7.8 0.2 2.8 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V Cwf_Cwc_15 PF04889.12 KXL50221.1 - 1.2e-78 264.2 17.7 1.8e-78 263.7 17.7 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SAPS PF04499.15 KXL50221.1 - 4 6.1 7.3 4.9 5.8 7.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RNase_PH PF01138.21 KXL50222.1 - 1.5e-23 83.7 0.0 2.2e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KXL50222.1 - 3.4e-07 30.2 0.0 5.9e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Glycos_transf_2 PF00535.26 KXL50223.1 - 1.3e-22 80.4 0.0 3.8e-22 78.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KXL50223.1 - 1.1e-05 25.5 0.0 0.078 12.8 0.0 3.1 2 1 1 3 3 3 2 Glycosyltransferase like family 2 IpgD PF05925.12 KXL50223.1 - 0.12 10.9 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 Enterobacterial virulence protein IpgD Acyltransferase PF01553.21 KXL50224.1 - 8.1e-14 51.4 0.0 1.5e-13 50.5 0.0 1.4 1 1 0 1 1 1 1 Acyltransferase PhoLip_ATPase_C PF16212.5 KXL50225.1 - 1.1e-80 271.1 21.4 1.1e-80 271.1 21.4 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KXL50225.1 - 1.3e-26 92.1 5.1 3.6e-26 90.7 5.1 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KXL50225.1 - 7.9e-12 45.1 0.1 3.5e-11 43.0 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXL50225.1 - 5.6e-10 39.8 3.6 6.9e-06 26.5 1.6 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KXL50225.1 - 3.9e-08 33.0 0.0 1.2e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KXL50225.1 - 0.0045 16.8 0.0 0.021 14.6 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase TPR_2 PF07719.17 KXL50227.1 - 0.0057 16.7 11.1 0.38 11.0 1.9 4.1 4 1 0 4 4 4 2 Tetratricopeptide repeat MIT PF04212.18 KXL50227.1 - 0.02 15.0 0.1 0.08 13.0 0.1 2.0 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_19 PF14559.6 KXL50227.1 - 0.13 12.7 8.1 1.7 9.2 0.3 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXL50227.1 - 0.23 11.4 6.8 0.22 11.4 1.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Rhomboid PF01694.22 KXL50228.1 - 7.7e-15 55.2 7.0 1.4e-14 54.4 7.0 1.3 1 0 0 1 1 1 1 Rhomboid family Gaa1 PF04114.14 KXL50229.1 - 1.6e-156 522.3 7.3 1.9e-156 522.0 7.3 1.0 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component PEMT PF04191.13 KXL50229.1 - 0.47 10.9 0.1 0.47 10.9 0.1 2.8 3 0 0 3 3 3 0 Phospholipid methyltransferase AIM24 PF01987.17 KXL50230.1 - 1.7e-47 161.9 0.1 1.9e-47 161.7 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF2917 PF11142.8 KXL50230.1 - 0.024 14.0 0.0 0.23 10.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2917) Cullin PF00888.22 KXL50231.1 - 6.4e-10 38.3 0.0 9.9e-10 37.7 0.0 1.2 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 KXL50231.1 - 0.0022 18.4 0.0 0.0057 17.1 0.0 1.8 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 SelB-wing_2 PF09106.11 KXL50231.1 - 0.092 13.0 0.3 31 4.9 0.1 3.1 3 0 0 3 3 3 0 Elongation factor SelB, winged helix CDP-OH_P_transf PF01066.21 KXL50232.1 - 1.1e-13 51.7 0.5 2.6e-13 50.5 0.1 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Epimerase PF01370.21 KXL50233.1 - 2.1e-16 60.1 0.0 4.1e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KXL50233.1 - 9.4e-13 48.3 0.0 1.2e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXL50233.1 - 2.9e-12 46.8 0.0 6e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXL50233.1 - 9.5e-10 37.9 0.0 2e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXL50233.1 - 5.4e-09 35.9 0.0 8.2e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KXL50233.1 - 1.1e-05 24.6 0.0 0.00021 20.5 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 KXL50233.1 - 8.7e-05 22.1 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 KXL50233.1 - 0.0012 18.0 0.4 0.051 12.7 0.1 2.6 2 1 1 3 3 3 1 Male sterility protein adh_short_C2 PF13561.6 KXL50233.1 - 0.0074 15.9 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL50233.1 - 0.066 13.1 0.0 2 8.3 0.0 2.3 2 0 0 2 2 2 0 KR domain YcbB PF08664.10 KXL50233.1 - 0.1 12.6 0.0 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 YcbB domain Polysacc_synt_2 PF02719.15 KXL50233.1 - 0.17 11.0 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PCI PF01399.27 KXL50234.1 - 1.3e-10 41.7 0.3 3.3e-10 40.4 0.3 1.8 1 0 0 1 1 1 1 PCI domain Dimerisation2 PF16864.5 KXL50234.1 - 0.11 12.5 1.7 0.37 10.8 0.1 2.5 2 1 1 3 3 3 0 Dimerisation domain SPX PF03105.19 KXL50235.1 - 2.3e-43 149.6 0.2 4.2e-43 148.7 0.2 1.4 1 1 0 1 1 1 1 SPX domain zf-C3HC4_2 PF13923.6 KXL50235.1 - 0.00059 19.6 11.4 0.0012 18.6 11.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXL50235.1 - 0.0032 17.3 10.0 0.0057 16.5 10.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXL50235.1 - 0.0034 17.5 11.4 0.0037 17.4 9.8 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KXL50235.1 - 0.02 14.7 9.7 0.02 14.7 9.7 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF572 PF04502.13 KXL50235.1 - 0.039 13.6 0.8 0.039 13.6 0.8 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF572) zf-RING_5 PF14634.6 KXL50235.1 - 0.15 12.0 9.2 0.3 11.1 9.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.6 KXL50235.1 - 0.91 9.4 10.5 3.1 7.6 10.6 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DZR PF12773.7 KXL50235.1 - 1.2 9.3 7.4 4.7 7.3 7.5 1.9 1 1 0 1 1 1 0 Double zinc ribbon DNA_ligase_ZBD PF03119.16 KXL50235.1 - 4.1 7.5 8.9 4.3 7.4 0.0 3.1 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain GST_N_3 PF13417.6 KXL50236.1 - 3.3e-21 75.5 0.1 9.6e-21 74.0 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXL50236.1 - 5e-20 71.6 0.5 9.6e-20 70.7 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXL50236.1 - 2.4e-13 50.2 0.3 5e-13 49.2 0.3 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXL50236.1 - 2.5e-08 33.8 0.1 8.4e-08 32.1 0.1 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXL50236.1 - 0.0011 19.2 0.0 0.0026 17.9 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXL50236.1 - 0.0014 18.7 0.0 0.003 17.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KXL50236.1 - 0.0016 18.6 0.0 0.0038 17.4 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin GST_C_5 PF16865.5 KXL50236.1 - 0.088 13.4 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.16 KXL50237.1 - 1.6e-21 76.7 24.4 7.6e-21 74.4 24.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily RCC1 PF00415.18 KXL50238.1 - 1.4e-27 96.0 1.8 1.2e-05 25.9 0.0 6.2 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KXL50238.1 - 6.6e-13 48.1 1.0 6.6e-13 48.1 1.0 5.2 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat HAD_SAK_1 PF10307.9 KXL50239.1 - 1.2e-73 247.3 0.1 1.8e-73 246.7 0.1 1.3 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins DUF1694 PF07997.11 KXL50239.1 - 0.012 15.7 0.0 0.1 12.7 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1694) Glyco_hydro_76 PF03663.14 KXL50240.1 - 2.3e-43 149.1 7.4 3.3e-43 148.6 7.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KXL50240.1 - 3.2e-06 26.4 2.1 0.0055 15.8 0.0 2.6 3 0 0 3 3 3 2 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 KXL50240.1 - 0.00019 20.1 0.4 0.0013 17.4 0.5 1.9 1 1 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Sporozoite_P67 PF05642.11 KXL50240.1 - 2.1 6.3 7.6 2.8 5.9 7.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FHA PF00498.26 KXL50241.1 - 1.4e-16 60.5 0.1 2.8e-16 59.6 0.1 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KXL50241.1 - 0.00011 22.4 0.0 0.0054 17.0 0.0 2.3 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF4878 PF12870.7 KXL50242.1 - 0.0077 16.5 0.1 6.2 7.2 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4878) LPP PF04728.13 KXL50242.1 - 0.022 15.1 0.2 1.8 9.0 0.0 2.7 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DLP_helical PF18709.1 KXL50242.1 - 0.12 11.6 1.5 0.43 9.7 0.5 1.9 1 1 1 2 2 2 0 Dynamin-like helical domain SEN1_N PF12726.7 KXL50243.1 - 0.098 10.9 0.0 0.13 10.4 0.0 1.1 1 0 0 1 1 1 0 SEN1 N terminal Aldedh PF00171.22 KXL50244.1 - 3.2e-97 326.0 0.0 3.7e-95 319.2 0.0 2.9 1 1 0 1 1 1 1 Aldehyde dehydrogenase family TPP_enzyme_C PF02775.21 KXL50245.1 - 5.3e-13 49.0 0.1 7.6e-13 48.5 0.1 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Coatomer_g_Cpla PF16381.5 KXL50245.1 - 0.03 14.4 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 Coatomer subunit gamma-1 C-terminal appendage platform TPR_1 PF00515.28 KXL50247.1 - 1.3e-34 116.6 22.2 2.3e-05 24.0 0.0 14.8 15 0 0 15 15 15 6 Tetratricopeptide repeat TPR_2 PF07719.17 KXL50247.1 - 5.8e-30 101.0 45.2 0.00045 20.1 0.0 16.7 20 0 0 20 20 17 6 Tetratricopeptide repeat TPR_19 PF14559.6 KXL50247.1 - 8.7e-29 99.8 20.8 1.3e-06 28.8 0.1 11.6 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_8 PF13181.6 KXL50247.1 - 5e-27 91.8 22.4 0.063 13.5 0.0 14.3 15 0 0 15 15 14 6 Tetratricopeptide repeat TPR_16 PF13432.6 KXL50247.1 - 9.4e-27 93.4 35.5 3.2e-05 24.5 0.1 13.7 13 2 2 15 15 12 7 Tetratricopeptide repeat TPR_17 PF13431.6 KXL50247.1 - 5.9e-26 89.0 10.8 0.076 13.4 0.0 14.1 15 0 0 15 15 13 6 Tetratricopeptide repeat TPR_14 PF13428.6 KXL50247.1 - 7.1e-21 73.1 43.1 0.011 16.5 0.0 16.7 16 4 4 20 20 15 6 Tetratricopeptide repeat TPR_11 PF13414.6 KXL50247.1 - 1.4e-20 72.7 19.2 7.1e-05 22.4 0.0 12.2 13 1 1 14 14 14 4 TPR repeat TPR_12 PF13424.6 KXL50247.1 - 3.9e-18 65.5 46.1 0.00084 19.6 0.1 13.5 12 3 2 14 14 13 6 Tetratricopeptide repeat TPR_7 PF13176.6 KXL50247.1 - 1.7e-14 52.7 26.1 0.043 13.9 0.0 13.0 15 1 1 16 16 14 4 Tetratricopeptide repeat TPR_9 PF13371.6 KXL50247.1 - 7.3e-09 35.7 12.8 0.00011 22.3 0.2 8.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXL50247.1 - 1.5e-08 34.7 28.6 0.017 15.7 0.0 14.7 18 0 0 18 18 15 2 Tetratricopeptide repeat TPR_20 PF14561.6 KXL50247.1 - 8.6e-05 22.8 16.4 1.2 9.5 0.0 9.7 10 2 1 11 11 10 1 Tetratricopeptide repeat TPR_22 PF18833.1 KXL50247.1 - 0.00016 21.8 0.1 0.0019 18.3 0.0 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_4 PF07721.14 KXL50247.1 - 0.023 15.3 28.8 0.36 11.6 0.0 10.3 13 0 0 13 13 8 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXL50247.1 - 0.029 14.3 16.8 3.9 7.5 0.0 8.8 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_3 PF07720.12 KXL50247.1 - 0.038 14.0 0.8 7.2 6.7 0.0 4.5 3 0 0 3 3 3 0 Tetratricopeptide repeat ChAPs PF09295.10 KXL50247.1 - 0.055 12.5 0.3 33 3.3 0.0 4.6 4 1 0 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) ANAPC3 PF12895.7 KXL50247.1 - 0.067 13.4 26.5 8.7 6.6 0.0 10.1 8 4 4 13 13 13 0 Anaphase-promoting complex, cyclosome, subunit 3 TOM20_plant PF06552.12 KXL50247.1 - 0.094 12.5 3.3 7.4 6.3 0.0 3.9 4 0 0 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 Sel1 PF08238.12 KXL50247.1 - 0.2 12.4 3.8 18 6.2 0.7 4.6 4 0 0 4 4 2 0 Sel1 repeat BTAD PF03704.17 KXL50247.1 - 0.55 10.7 17.6 17 5.8 4.5 6.0 5 2 0 5 5 5 0 Bacterial transcriptional activator domain HTH_psq PF05225.16 KXL50250.1 - 0.00061 19.5 0.3 0.001 18.7 0.3 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain NUDIX PF00293.28 KXL50252.1 - 0.027 14.5 0.0 0.051 13.6 0.0 1.5 1 0 0 1 1 1 0 NUDIX domain MethyltransfD12 PF02086.15 KXL50254.1 - 0.0014 18.4 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase ABC_tran PF00005.27 KXL50255.1 - 9.1e-35 120.1 0.0 1.4e-16 61.3 0.0 2.8 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXL50255.1 - 4.5e-25 88.8 22.0 5.1e-22 78.8 11.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_16 PF13191.6 KXL50255.1 - 1.7e-05 25.3 0.1 0.22 11.9 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_7 PF12775.7 KXL50255.1 - 3.1e-05 23.6 0.1 0.23 11.0 0.0 3.2 3 0 0 3 3 3 2 P-loop containing dynein motor region T2SSE PF00437.20 KXL50255.1 - 7.7e-05 21.9 0.9 0.023 13.8 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 KXL50255.1 - 8.7e-05 22.2 1.3 0.015 15.0 0.1 2.9 3 0 0 3 3 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 KXL50255.1 - 9.5e-05 21.9 0.0 0.21 11.0 0.2 3.3 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXL50255.1 - 0.00012 22.3 1.8 2.3 8.5 0.4 3.5 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 KXL50255.1 - 0.0014 18.6 0.0 1.1 9.1 0.0 2.6 2 0 0 2 2 2 2 NACHT domain FtsK_SpoIIIE PF01580.18 KXL50255.1 - 0.0022 17.4 0.3 0.29 10.5 0.1 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family Viral_helicase1 PF01443.18 KXL50255.1 - 0.0035 17.1 0.3 3.2 7.4 0.0 2.6 3 0 0 3 3 2 2 Viral (Superfamily 1) RNA helicase SbcCD_C PF13558.6 KXL50255.1 - 0.0067 16.6 0.1 1.7 8.9 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit cobW PF02492.19 KXL50255.1 - 0.0075 15.9 2.5 0.44 10.1 0.2 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 KXL50255.1 - 0.0085 16.0 1.9 2.7 7.9 0.1 2.7 3 0 0 3 3 2 2 RsgA GTPase DEAD PF00270.29 KXL50255.1 - 0.013 15.3 0.0 0.56 10.0 0.0 2.7 2 1 0 2 2 2 0 DEAD/DEAH box helicase NTPase_1 PF03266.15 KXL50255.1 - 0.02 14.8 0.7 0.081 12.8 0.1 2.3 2 0 0 2 2 2 0 NTPase AAA_21 PF13304.6 KXL50255.1 - 0.022 14.6 1.9 0.54 10.0 0.1 2.7 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 KXL50255.1 - 0.033 14.4 1.0 16 5.7 0.0 3.5 3 1 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KXL50255.1 - 0.07 12.9 0.8 2.2 8.0 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.6 KXL50255.1 - 0.073 12.6 0.8 3 7.4 0.1 2.8 3 0 0 3 3 3 0 AAA domain CbiA PF01656.23 KXL50255.1 - 0.12 12.4 0.2 0.36 10.9 0.0 1.9 2 0 0 2 2 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_19 PF13245.6 KXL50255.1 - 0.14 12.5 0.3 2.8 8.3 0.0 2.7 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KXL50255.1 - 0.15 12.1 2.3 6.2 6.9 0.2 3.2 4 0 0 4 4 3 0 50S ribosome-binding GTPase Pox_A32 PF04665.12 KXL50255.1 - 0.33 10.4 1.3 1.9 7.9 0.2 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_23 PF13476.6 KXL50255.1 - 0.55 10.7 2.0 1.7 9.1 0.2 2.1 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KXL50255.1 - 1.5 8.9 5.3 3.7 7.6 0.5 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain SLATT_1 PF18181.1 KXL50256.1 - 0.13 12.2 0.3 0.31 11.0 0.2 1.6 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 DDE_3 PF13358.6 KXL50257.1 - 1.3e-06 28.2 0.6 1.9e-06 27.7 0.6 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Phage_TAC_4 PF08748.11 KXL50257.1 - 0.047 14.0 0.0 0.064 13.6 0.0 1.2 1 0 0 1 1 1 0 Phage tail assembly chaperone Se-cys_synth_N PF12390.8 KXL50257.1 - 0.059 13.6 0.1 0.15 12.3 0.1 1.6 2 0 0 2 2 2 0 Selenocysteine synthase N terminal SGL PF08450.12 KXL50259.1 - 3.4e-62 210.2 0.1 4.3e-62 209.9 0.1 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KXL50259.1 - 0.038 14.1 0.0 0.086 13.0 0.0 1.5 1 0 0 1 1 1 0 Strictosidine synthase Arylesterase PF01731.20 KXL50259.1 - 0.073 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Arylesterase XPG_N PF00752.17 KXL50260.1 - 1.5e-34 118.5 0.0 4.1e-34 117.1 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KXL50260.1 - 1.4e-26 92.7 0.0 4.3e-26 91.1 0.0 1.9 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 KXL50260.1 - 0.0022 18.6 0.0 0.0077 16.8 0.0 2.0 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold UIM PF02809.20 KXL50260.1 - 0.0023 17.7 1.1 0.0023 17.7 1.1 3.5 3 0 0 3 3 3 1 Ubiquitin interaction motif Transposase_20 PF02371.16 KXL50260.1 - 0.031 14.6 0.0 0.085 13.2 0.0 1.7 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family HHH PF00633.23 KXL50260.1 - 0.085 12.8 0.1 0.27 11.2 0.1 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif HET PF06985.11 KXL50262.1 - 3.5e-30 105.3 0.0 8.2e-30 104.1 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pex19 PF04614.12 KXL50262.1 - 0.19 11.5 0.5 0.37 10.5 0.5 1.4 1 0 0 1 1 1 0 Pex19 protein family EVE PF01878.18 KXL50263.1 - 3.8e-36 124.2 0.2 7.9e-36 123.2 0.2 1.6 1 0 0 1 1 1 1 EVE domain NIBRIN_BRCT_II PF16508.5 KXL50264.1 - 1e-16 61.3 0.3 3e-16 59.8 0.1 2.0 2 0 0 2 2 2 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 KXL50264.1 - 2.7e-05 24.4 0.2 6.4e-05 23.2 0.2 1.6 1 0 0 1 1 1 1 FHA domain PIP5K PF01504.18 KXL50265.1 - 1.9e-35 122.4 10.6 4.3e-30 104.9 0.3 2.8 2 1 1 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 KXL50265.1 - 4.4e-28 98.2 0.1 7.4e-28 97.4 0.1 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 KXL50265.1 - 4.7e-14 52.3 3.3 4.7e-14 52.3 3.3 2.3 2 0 0 2 2 2 1 FYVE zinc finger C1_1 PF00130.22 KXL50265.1 - 0.14 12.1 12.2 0.016 15.1 3.8 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.7 KXL50265.1 - 0.24 11.4 9.8 0.43 10.7 4.3 2.7 2 0 0 2 2 2 0 Double zinc ribbon YhfH PF14149.6 KXL50265.1 - 6.2 6.9 11.4 0.25 11.3 1.0 3.1 2 1 1 3 3 3 0 YhfH-like protein TPP1 PF10341.9 KXL50266.1 - 2e-08 34.2 0.0 6.1e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 Shelterin complex subunit, TPP1/ACD DUF812 PF05667.11 KXL50266.1 - 0.29 10.0 1.8 0.43 9.4 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Ribosomal_S5 PF00333.20 KXL50267.1 - 9.4e-27 92.8 0.5 2.4e-26 91.5 0.5 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KXL50267.1 - 5.3e-24 83.5 0.1 8.7e-24 82.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 KXL50267.1 - 4.1 8.0 15.3 9.5 6.9 15.3 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 NAD_binding_6 PF08030.12 KXL50268.1 - 1.9e-06 28.1 0.0 4.9e-05 23.5 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KXL50268.1 - 1.3e-05 25.8 0.1 0.00032 21.3 0.1 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KXL50268.1 - 0.04 14.3 0.0 0.067 13.6 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain DUF1932 PF09130.11 KXL50269.1 - 4.2e-22 77.9 0.0 9.6e-22 76.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.15 KXL50269.1 - 1.4e-06 28.6 0.0 2.5e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KXL50269.1 - 1.7e-05 25.3 0.1 3.9e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KXL50269.1 - 0.039 13.9 0.1 0.087 12.7 0.1 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.9 KXL50269.1 - 0.086 12.7 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Rossmann-like domain AIRC PF00731.20 KXL50269.1 - 0.12 12.0 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 AIR carboxylase HTH_39 PF14090.6 KXL50269.1 - 0.13 12.1 0.0 2.8 7.8 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain Peptidase_M22 PF00814.25 KXL50270.1 - 1.4e-48 166.0 0.0 2e-23 83.5 0.3 3.0 2 1 0 2 2 2 2 Glycoprotease family Pil1 PF13805.6 KXL50271.1 - 9.7e-128 425.2 0.9 1.4e-127 424.7 0.9 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 GP67 PF17634.2 KXL50271.1 - 0.048 14.1 4.8 11 6.5 3.3 2.5 2 0 0 2 2 2 0 Gene product 67 FAM92 PF06730.11 KXL50271.1 - 0.07 12.5 2.2 0.11 11.9 0.9 1.9 1 1 1 2 2 2 0 FAM92 protein NOA36 PF06524.12 KXL50271.1 - 3.9 6.7 6.4 6.2 6.0 6.4 1.3 1 0 0 1 1 1 0 NOA36 protein DHDPS PF00701.22 KXL50272.1 - 1.3e-35 122.6 0.1 1.5e-35 122.4 0.1 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family MFS_1 PF07690.16 KXL50273.1 - 1.5e-20 73.4 46.5 1.5e-20 73.4 46.5 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXL50273.1 - 2.6e-20 72.4 22.5 3.4e-20 72.0 22.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CDC45 PF02724.14 KXL50274.1 - 0.034 12.4 4.8 0.035 12.4 4.8 1.1 1 0 0 1 1 1 0 CDC45-like protein UBA2_C PF16195.5 KXL50274.1 - 4.2 8.1 8.9 1.1 10.0 4.5 2.4 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus BolA PF01722.18 KXL50275.1 - 8e-29 99.7 1.2 9.5e-29 99.5 1.2 1.1 1 0 0 1 1 1 1 BolA-like protein adh_short PF00106.25 KXL50276.1 - 1.6e-18 66.8 0.1 7.3e-18 64.7 0.2 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL50276.1 - 3.9e-09 36.4 0.0 1.7e-07 31.1 0.1 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL50276.1 - 2e-08 34.4 0.1 3.1e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 KR domain SET PF00856.28 KXL50279.1 - 1.8e-14 54.5 2.2 3.1e-14 53.7 0.1 2.3 2 1 0 2 2 2 1 SET domain preSET_CXC PF18264.1 KXL50279.1 - 3.9e-07 30.4 31.4 2.4e-06 27.9 13.6 3.3 2 1 1 3 3 3 3 CXC domain Cyt-b5 PF00173.28 KXL50281.1 - 4.6e-16 58.7 0.0 7e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MatP PF06303.12 KXL50282.1 - 0.051 14.1 0.4 0.065 13.8 0.4 1.1 1 0 0 1 1 1 0 MatP N-terminal domain Spc7 PF08317.11 KXL50283.1 - 9.1e-96 320.4 2.7 1.5e-95 319.7 2.7 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_N PF15402.6 KXL50283.1 - 8.7e-86 289.1 70.4 6.3e-72 243.2 26.1 4.9 2 1 1 3 3 3 3 N-terminus of kinetochore NMS complex subunit Spc7 Spc7_C2 PF15577.6 KXL50283.1 - 9.1e-13 48.1 0.4 1.9e-12 47.0 0.4 1.5 1 0 0 1 1 1 1 Spc7_C2 DUF4472 PF14739.6 KXL50283.1 - 0.012 16.3 7.4 0.2 12.4 6.7 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) RasGAP_C PF03836.15 KXL50283.1 - 0.026 14.6 0.0 0.066 13.4 0.0 1.6 1 0 0 1 1 1 0 RasGAP C-terminus HAUS-augmin3 PF14932.6 KXL50283.1 - 0.043 13.4 3.3 0.1 12.2 3.3 1.6 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 kleA_kleC PF17383.2 KXL50283.1 - 0.061 13.6 2.9 0.19 12.1 2.9 1.9 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A PriC PF07445.12 KXL50283.1 - 0.099 12.6 8.3 6.6 6.6 6.4 2.7 2 0 0 2 2 2 0 Primosomal replication protein priC Golgin_A5 PF09787.9 KXL50283.1 - 0.46 9.9 9.7 0.92 8.9 9.0 1.8 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF1664 PF07889.12 KXL50283.1 - 5.6 7.0 5.4 2.9 7.9 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 KXL50283.1 - 7.2 7.1 5.9 5.1 7.6 2.4 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Ribosomal_S17_N PF16205.5 KXL50284.1 - 8.7e-34 115.7 0.3 1.3e-33 115.1 0.3 1.3 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 KXL50284.1 - 1.3e-26 92.5 0.3 2.2e-26 91.7 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 DUF1748 PF08520.10 KXL50285.1 - 3e-32 110.3 0.1 3.3e-32 110.2 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) PK PF00224.21 KXL50286.1 - 4.5e-172 571.7 2.0 5.4e-172 571.4 2.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KXL50286.1 - 1.7e-38 131.4 0.0 5e-38 129.9 0.0 1.8 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KXL50286.1 - 0.0013 17.9 0.2 0.0039 16.4 0.1 1.8 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 KXL50286.1 - 0.045 12.7 0.0 0.18 10.8 0.0 1.8 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain NGP1NT PF08153.12 KXL50288.1 - 3.6e-50 169.5 0.4 6.3e-50 168.7 0.4 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KXL50288.1 - 6.3e-16 58.5 0.0 4.9e-13 49.2 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KXL50288.1 - 0.00059 19.4 0.0 0.002 17.7 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 KXL50288.1 - 0.0017 17.8 0.0 0.23 10.9 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KXL50288.1 - 0.0023 17.9 0.0 0.006 16.5 0.0 1.7 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 KXL50288.1 - 0.003 17.1 0.0 0.24 10.9 0.0 3.1 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KXL50288.1 - 0.057 13.5 4.1 0.88 9.6 0.0 3.6 3 1 1 4 4 4 0 Dynamin family MRP-S26 PF14943.6 KXL50289.1 - 0.0064 16.4 7.2 0.85 9.5 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial ribosome subunit S26 tRNA-synt_2d PF01409.20 KXL50290.1 - 0.015 14.8 0.0 0.017 14.6 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) Ribophorin_II PF05817.14 KXL50291.1 - 5.9e-27 94.5 0.0 6.9e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II DIL PF01843.19 KXL50292.1 - 0.25 11.6 2.4 0.74 10.1 0.5 2.4 2 0 0 2 2 2 0 DIL domain adh_short_C2 PF13561.6 KXL50293.1 - 5.4e-55 186.5 0.2 6.3e-55 186.3 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL50293.1 - 3e-46 157.4 1.2 4e-46 156.9 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL50293.1 - 4.2e-14 52.9 0.2 5.8e-14 52.4 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL50293.1 - 0.00061 19.3 0.0 0.00084 18.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXL50293.1 - 0.02 14.3 0.0 0.035 13.5 0.0 1.4 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase p450 PF00067.22 KXL50294.1 - 7.4e-30 104.1 0.0 3e-22 79.0 0.0 3.0 1 1 1 2 2 2 2 Cytochrome P450 Cu-oxidase_3 PF07732.15 KXL50295.1 - 6.3e-12 45.6 0.0 8.9e-08 32.2 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXL50295.1 - 7.4e-12 45.2 0.0 0.00065 19.4 0.1 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cupredoxin_1 PF13473.6 KXL50295.1 - 0.0032 17.6 0.0 0.71 10.0 0.0 2.5 2 0 0 2 2 2 2 Cupredoxin-like domain BslA PF17735.1 KXL50295.1 - 0.036 14.1 0.0 0.066 13.2 0.0 1.3 1 0 0 1 1 1 0 Biofilm surface layer A ECH_1 PF00378.20 KXL50296.1 - 9.9e-27 93.8 0.1 1.1e-26 93.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXL50296.1 - 9.9e-16 58.1 0.1 1.1e-15 57.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Pet100 PF09803.9 KXL50297.1 - 1e-17 64.4 0.0 1.9e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Pet100 DUF5621 PF18532.1 KXL50297.1 - 0.048 13.6 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5621) EF-1_beta_acid PF10587.9 KXL50297.1 - 0.69 10.4 8.9 0.51 10.8 2.8 2.4 1 1 1 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region BTB PF00651.31 KXL50298.1 - 5e-13 49.2 0.2 1.9e-12 47.4 0.1 1.9 2 0 0 2 2 2 1 BTB/POZ domain Skp1_POZ PF03931.15 KXL50298.1 - 0.012 15.7 1.8 0.036 14.2 0.3 2.6 3 0 0 3 3 3 0 Skp1 family, tetramerisation domain Acetyltransf_3 PF13302.7 KXL50299.1 - 1.4e-16 61.4 0.0 1.7e-16 61.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXL50299.1 - 0.0052 17.0 0.0 0.0075 16.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Chromo PF00385.24 KXL50300.1 - 2.2e-07 30.6 0.1 4.7e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCCH_4 PF18044.1 KXL50300.1 - 0.0019 18.0 8.0 0.042 13.7 0.8 3.0 2 0 0 2 2 2 2 CCCH-type zinc finger Chs7 PF12271.8 KXL50301.1 - 9.9e-103 343.4 6.6 1.2e-102 343.2 6.6 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Ras PF00071.22 KXL50302.1 - 1.5e-49 167.7 1.8 5e-48 162.7 1.8 2.1 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KXL50302.1 - 1.1e-29 103.1 0.4 4.4e-20 72.1 0.1 2.4 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXL50302.1 - 1.1e-11 44.5 0.1 5.9e-10 38.9 0.1 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXL50302.1 - 6.1e-08 32.4 0.1 1.6e-07 31.0 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KXL50302.1 - 2.7e-06 26.9 0.1 5.5e-06 25.9 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXL50302.1 - 0.00038 20.5 0.3 0.0027 17.8 0.1 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXL50302.1 - 0.067 13.1 0.6 2.5 8.0 0.0 2.4 2 1 0 2 2 2 0 RsgA GTPase Lysine_decarbox PF03641.14 KXL50303.1 - 2.3e-30 105.4 0.0 3.4e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KXL50303.1 - 0.00025 20.7 0.1 0.0072 15.9 0.0 2.2 2 0 0 2 2 2 1 SLOG cluster4 family LSDAT_prok PF18171.1 KXL50303.1 - 0.1 11.9 0.3 0.23 10.7 0.0 1.7 2 0 0 2 2 2 0 SLOG in TRPM, prokaryote STN PF07660.14 KXL50303.1 - 0.19 11.5 0.0 0.83 9.5 0.0 1.9 2 0 0 2 2 2 0 Secretin and TonB N terminus short domain Sugar_tr PF00083.24 KXL50304.1 - 3.3e-99 332.8 14.5 4e-99 332.5 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL50304.1 - 3.8e-27 95.2 26.8 7.9e-27 94.1 19.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXL50304.1 - 3.1e-07 29.3 1.9 3.1e-07 29.3 1.9 3.3 4 0 0 4 4 4 2 MFS/sugar transport protein MFS_1_like PF12832.7 KXL50304.1 - 0.0034 16.3 9.5 0.061 12.2 0.1 2.4 1 1 0 2 2 2 2 MFS_1 like family CDC50 PF03381.15 KXL50305.1 - 3.4e-95 318.8 0.0 4.3e-95 318.4 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Pex16 PF08610.10 KXL50306.1 - 5.2e-134 446.5 0.1 5.9e-134 446.3 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) HD PF01966.22 KXL50308.1 - 1.4e-06 28.5 0.7 2.9e-06 27.5 0.3 1.8 2 0 0 2 2 2 1 HD domain HDOD PF08668.12 KXL50308.1 - 0.022 14.3 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 HDOD domain SRI PF08236.11 KXL50308.1 - 0.049 13.8 1.0 7.8 6.7 0.1 2.9 2 1 1 3 3 3 0 SRI (Set2 Rpb1 interacting) domain MitMem_reg PF13012.6 KXL50309.1 - 1.1e-36 125.7 0.1 2e-36 124.8 0.1 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KXL50309.1 - 9.3e-31 106.3 0.0 3.3e-30 104.5 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease tRNA_bind_2 PF13725.6 KXL50309.1 - 0.001 18.8 2.4 0.0014 18.4 2.4 1.2 1 0 0 1 1 1 1 Possible tRNA binding domain Connexin PF00029.19 KXL50309.1 - 0.28 10.9 2.4 0.44 10.3 2.4 1.2 1 0 0 1 1 1 0 Connexin CobT PF06213.12 KXL50309.1 - 2.7 7.3 10.4 3.7 6.9 10.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1682 PF07946.14 KXL50309.1 - 4.8 6.3 11.8 7.1 5.7 11.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) SWIM PF04434.17 KXL50310.1 - 9.6e-05 22.0 0.4 0.01 15.5 0.0 2.3 2 0 0 2 2 2 2 SWIM zinc finger SWIRM PF04433.17 KXL50312.1 - 3.2e-10 40.2 0.1 1.4e-09 38.2 0.0 1.9 2 0 0 2 2 2 1 SWIRM domain EF-hand_4 PF12763.7 KXL50313.1 - 3.4e-38 129.8 0.0 5e-16 58.5 0.0 3.6 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 KXL50313.1 - 6.2e-08 33.0 0.0 0.00051 20.4 0.1 3.8 3 1 0 3 3 3 1 EF-hand domain pair UBA PF00627.31 KXL50313.1 - 1.5e-05 24.8 0.0 4.4e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_1 PF00036.32 KXL50313.1 - 5.4e-05 22.5 1.7 0.51 10.0 0.0 5.2 6 0 0 6 6 6 1 EF hand EF-hand_8 PF13833.6 KXL50313.1 - 0.00023 20.9 0.0 3.9 7.4 0.0 4.0 4 0 0 4 4 4 2 EF-hand domain pair Macoilin PF09726.9 KXL50313.1 - 0.00068 18.3 23.4 0.00068 18.3 23.4 2.9 2 1 1 3 3 2 1 Macoilin family EF-hand_6 PF13405.6 KXL50313.1 - 0.0036 17.1 0.2 24 5.2 0.1 5.1 5 0 0 5 5 5 0 EF-hand domain IFT57 PF10498.9 KXL50313.1 - 0.1 11.5 26.3 0.0046 16.0 20.1 1.9 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 FUSC PF04632.12 KXL50313.1 - 0.13 10.8 11.3 0.23 10.0 11.3 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family HBS1_N PF08938.10 KXL50313.1 - 0.15 12.4 0.1 0.15 12.4 0.1 2.7 3 0 0 3 3 1 0 HBS1 N-terminus DUF1192 PF06698.11 KXL50313.1 - 0.17 12.0 2.5 0.48 10.5 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TPR_MLP1_2 PF07926.12 KXL50313.1 - 0.27 11.3 38.6 2.9 7.9 11.3 3.5 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KXL50313.1 - 0.28 10.0 38.8 0.3 9.9 21.6 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 KXL50313.1 - 0.37 10.8 16.1 0.27 11.3 8.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GAS PF13851.6 KXL50313.1 - 0.66 9.3 34.8 0.69 9.2 15.5 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.8 KXL50313.1 - 0.85 7.1 32.8 1.4 6.3 32.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CENP-F_leu_zip PF10473.9 KXL50313.1 - 0.9 9.6 34.5 1.3 9.0 12.8 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prominin PF05478.11 KXL50313.1 - 1.7 6.5 14.2 2.5 5.9 14.2 1.1 1 0 0 1 1 1 0 Prominin Filament PF00038.21 KXL50313.1 - 1.9 8.0 32.9 21 4.6 33.0 2.0 1 1 0 1 1 1 0 Intermediate filament protein Fib_alpha PF08702.10 KXL50313.1 - 3.1 8.0 23.6 0.12 12.6 10.5 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Occludin_ELL PF07303.13 KXL50313.1 - 8.5 7.2 13.0 2.8 8.7 7.1 2.8 1 1 2 3 3 3 0 Occludin homology domain FlaC_arch PF05377.11 KXL50313.1 - 8.9 6.8 11.8 12 6.4 0.2 3.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Methyltransf_11 PF08241.12 KXL50314.1 - 7.5e-14 52.1 0.0 1.6e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL50314.1 - 6.7e-11 42.7 0.0 1.3e-10 41.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL50314.1 - 7.8e-09 36.2 0.0 1.3e-08 35.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL50314.1 - 8.8e-08 32.1 0.0 1.4e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXL50314.1 - 0.0001 22.1 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXL50314.1 - 0.00028 20.3 0.0 0.0004 19.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_PK PF05891.12 KXL50314.1 - 0.048 13.2 0.0 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase MTS PF05175.14 KXL50314.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain FAD_binding_3 PF01494.19 KXL50315.1 - 4.8e-46 157.6 0.0 5.7e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXL50315.1 - 1.7e-06 27.5 0.0 3.5e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXL50315.1 - 0.00036 19.8 0.4 0.31 10.1 0.2 2.1 1 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 KXL50315.1 - 0.00047 19.9 0.3 0.086 12.4 0.1 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXL50315.1 - 0.0013 17.5 0.1 0.11 11.2 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Glu_dehyd_C PF16912.5 KXL50315.1 - 0.0042 16.6 0.0 0.013 15.0 0.0 1.7 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus Pyr_redox_3 PF13738.6 KXL50315.1 - 0.0053 16.1 0.1 0.23 10.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXL50315.1 - 0.0095 16.1 0.3 0.04 14.1 0.1 2.2 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXL50315.1 - 0.038 14.6 0.2 5.7 7.6 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXL50315.1 - 0.052 12.6 0.4 0.3 10.1 0.4 2.1 1 1 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.7 KXL50315.1 - 0.074 12.4 0.4 0.19 11.0 0.4 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase Mqo PF06039.15 KXL50315.1 - 0.088 11.3 0.0 0.14 10.6 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Thi4 PF01946.17 KXL50315.1 - 0.14 11.3 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.6 KXL50315.1 - 0.17 12.4 0.2 4.6 7.7 0.0 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding MFS_1 PF07690.16 KXL50316.1 - 6.7e-18 64.7 23.4 7.5e-18 64.6 23.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily TauD PF02668.16 KXL50317.1 - 2.6e-49 168.4 0.5 3.1e-49 168.2 0.5 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TPR_11 PF13414.6 KXL50317.1 - 0.038 13.7 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 TPR repeat Epimerase PF01370.21 KXL50318.1 - 1.3e-21 77.2 0.1 4e-21 75.6 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXL50318.1 - 1.8e-10 40.7 0.0 5.3e-10 39.2 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXL50318.1 - 4e-08 32.6 0.0 8.5e-08 31.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KXL50318.1 - 5.7e-08 32.2 0.0 9.6e-08 31.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KXL50318.1 - 2.6e-07 30.1 0.0 4.2e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 KXL50318.1 - 1.7e-06 27.4 0.2 0.00012 21.3 0.8 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KXL50318.1 - 0.00044 20.2 0.0 0.0015 18.5 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding MMU163 PF17119.5 KXL50319.1 - 1.3e-77 260.3 12.7 1.7e-76 256.7 12.7 2.3 1 1 0 1 1 1 1 Mitochondrial protein up-regulated during meiosis Tom5 PF10642.9 KXL50319.1 - 0.11 12.5 0.5 0.22 11.6 0.5 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase PAC3 PF10178.9 KXL50320.1 - 0.13 12.4 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Proteasome assembly chaperone 3 YbjQ_1 PF01906.17 KXL50321.1 - 7.2e-29 100.5 0.7 9.1e-29 100.2 0.7 1.1 1 0 0 1 1 1 1 Putative heavy-metal-binding HutP PF09021.11 KXL50321.1 - 0.0023 18.2 0.0 0.014 15.7 0.0 1.9 1 1 1 2 2 2 1 HutP KR PF08659.10 KXL50321.1 - 0.082 12.8 0.0 0.091 12.7 0.0 1.2 1 0 0 1 1 1 0 KR domain SeleniumBinding PF11524.8 KXL50321.1 - 0.18 12.3 0.4 6.8 7.2 0.1 2.3 1 1 0 2 2 2 0 Selenium binding protein HA2 PF04408.23 KXL50322.1 - 4.3e-12 46.3 0.0 4.3e-12 46.3 0.0 2.3 2 1 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KXL50322.1 - 1.9e-09 37.8 0.0 8.4e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KXL50322.1 - 3.2e-09 37.0 0.0 6.1e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KXL50322.1 - 2.4e-05 24.2 0.0 5.8e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 KXL50322.1 - 0.0013 17.9 0.0 0.0024 17.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 KXL50322.1 - 0.011 15.5 0.2 0.029 14.1 0.2 1.7 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KXL50322.1 - 0.014 14.8 0.0 0.037 13.4 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.6 KXL50322.1 - 0.044 14.1 1.4 1.9 8.8 0.4 2.8 2 1 0 2 2 2 0 AAA domain EBP50_C PF09007.11 KXL50322.1 - 0.12 13.3 5.8 0.32 12.0 5.8 1.7 1 0 0 1 1 1 0 EBP50, C-terminal AAA_33 PF13671.6 KXL50322.1 - 0.14 12.3 0.1 0.14 12.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KXL50322.1 - 0.18 12.1 0.2 0.46 10.8 0.2 1.7 1 0 0 1 1 1 0 AAA domain Macoilin PF09726.9 KXL50322.1 - 2 6.9 7.9 2.9 6.4 7.9 1.2 1 0 0 1 1 1 0 Macoilin family IBR PF01485.21 KXL50323.1 - 8.7e-17 61.1 35.6 5e-12 45.9 1.4 3.8 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain RWD PF05773.22 KXL50323.1 - 1.8e-16 60.5 0.1 4e-16 59.3 0.1 1.6 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 KXL50323.1 - 0.0005 20.3 9.4 0.0005 20.3 9.4 3.9 3 1 0 3 3 3 2 Ring finger domain zf-RING_UBOX PF13445.6 KXL50323.1 - 0.00051 20.0 7.5 0.00051 20.0 7.5 3.7 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXL50323.1 - 0.004 17.0 11.0 0.004 17.0 11.0 4.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXL50323.1 - 0.0046 16.9 10.4 0.0046 16.9 10.4 3.5 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_11 PF17123.5 KXL50323.1 - 0.0077 15.9 5.4 0.0077 15.9 5.4 2.2 2 0 0 2 2 2 1 RING-like zinc finger Ribosomal_L28e PF01778.17 KXL50324.1 - 4e-37 127.5 1.8 7.9e-37 126.5 1.8 1.5 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.14 KXL50324.1 - 1.7e-26 92.7 18.8 1.7e-26 92.7 18.8 2.4 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 KXL50324.1 - 0.00017 21.1 14.3 0.00023 20.7 14.3 1.1 1 0 0 1 1 1 1 BUD22 PYC_OADA PF02436.18 KXL50324.1 - 0.043 13.5 1.5 0.08 12.7 1.1 1.6 1 1 0 1 1 1 0 Conserved carboxylase domain Virulence_fact PF13769.6 KXL50324.1 - 9.6 6.5 9.9 3.5 7.9 0.9 3.1 3 1 0 3 3 3 0 Virulence factor FAD_binding_6 PF00970.24 KXL50325.1 - 1.3e-09 38.3 0.0 4.9e-09 36.5 0.0 2.0 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KXL50325.1 - 0.00025 21.6 0.0 0.012 16.2 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain MFS_1 PF07690.16 KXL50326.1 - 1.5e-36 126.1 51.3 1.5e-36 126.1 51.3 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL50326.1 - 0.004 16.1 8.3 0.004 16.1 8.3 3.6 2 2 0 3 3 3 2 Sugar (and other) transporter DUF43 PF01861.16 KXL50326.1 - 0.19 10.9 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Transcrip_reg PF01709.20 KXL50327.1 - 6.5e-68 228.7 0.2 7.4e-68 228.5 0.2 1.0 1 0 0 1 1 1 1 Transcriptional regulator NapD PF03927.13 KXL50327.1 - 0.12 12.5 1.5 1.7 8.8 0.7 2.4 1 1 1 2 2 2 0 NapD protein HEAT_2 PF13646.6 KXL50328.1 - 1.3e-09 38.3 0.5 0.00043 20.6 0.0 4.8 2 2 1 3 3 3 2 HEAT repeats Cnd1 PF12717.7 KXL50328.1 - 9.8e-05 22.4 0.0 0.0048 16.9 0.0 3.5 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KXL50328.1 - 0.00016 21.7 19.9 0.0021 18.1 0.1 7.7 8 0 0 8 8 8 2 HEAT repeat Vac14_Fab1_bd PF12755.7 KXL50328.1 - 0.00026 21.5 0.0 0.47 11.1 0.0 3.0 2 0 0 2 2 2 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KXL50328.1 - 0.006 17.1 10.2 2 9.0 0.1 5.6 3 1 1 4 4 4 2 HEAT-like repeat Cnd3 PF12719.7 KXL50328.1 - 0.011 15.0 1.6 0.47 9.6 0.1 3.0 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain IFRD PF05004.13 KXL50328.1 - 0.11 11.6 11.3 0.28 10.3 1.2 4.1 2 2 1 4 4 4 0 Interferon-related developmental regulator (IFRD) PAS_4 PF08448.10 KXL50329.1 - 0.00041 20.6 0.4 0.0011 19.2 0.1 1.8 1 1 1 2 2 2 1 PAS fold Sec7 PF01369.20 KXL50330.1 - 1.3e-61 207.5 0.0 2.1e-61 206.8 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KXL50330.1 - 1.5e-19 70.4 0.0 9.5e-19 67.8 0.0 2.3 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KXL50330.1 - 0.21 11.5 1.3 34 4.4 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) Ribosomal_L23 PF00276.20 KXL50331.1 - 1.1e-06 28.9 0.0 1.9e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 TRF PF08558.10 KXL50332.1 - 8.6e-51 172.8 0.0 1.3e-50 172.3 0.0 1.3 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 KXL50332.1 - 0.0002 21.5 0.1 0.00047 20.3 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF573 PF04504.14 KXL50332.1 - 0.02 15.6 0.5 0.39 11.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function, DUF573 Myb_DNA-bind_6 PF13921.6 KXL50332.1 - 0.024 14.9 0.6 0.072 13.3 0.1 2.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF1635 PF07795.11 KXL50332.1 - 0.075 12.9 3.6 2.6 7.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Androgen_recep PF02166.16 KXL50332.1 - 1.3 7.8 20.0 0.71 8.6 13.3 2.6 2 0 0 2 2 2 0 Androgen receptor Macoilin PF09726.9 KXL50332.1 - 2.7 6.5 6.1 0.94 8.0 2.8 1.7 2 0 0 2 2 2 0 Macoilin family Tyrosinase PF00264.20 KXL50334.1 - 1.6e-51 175.8 0.0 2.1e-51 175.3 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF2462 PF09495.10 KXL50335.1 - 2.7e-19 69.7 14.4 3e-19 69.5 14.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) 2_5_RNA_ligase2 PF13563.6 KXL50336.1 - 0.021 14.7 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily ThiS PF02597.20 KXL50337.1 - 1.2e-06 29.0 0.0 1.9e-06 28.4 0.0 1.3 1 1 0 1 1 1 1 ThiS family Abhydrolase_3 PF07859.13 KXL50338.1 - 7.5e-19 68.4 0.1 1e-17 64.7 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXL50338.1 - 1.9e-07 30.8 0.0 0.016 14.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 KXL50338.1 - 1.6e-05 24.0 0.0 2.3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme COesterase PF00135.28 KXL50338.1 - 4e-05 22.7 0.0 8.7e-05 21.6 0.0 1.5 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 KXL50338.1 - 6.9e-05 23.5 1.1 9.3e-05 23.1 1.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 KXL50338.1 - 0.00056 19.5 0.4 0.52 9.8 0.0 2.8 2 1 0 2 2 2 2 Esterase PHB depolymerase Chlorophyllase PF07224.11 KXL50338.1 - 0.0018 17.3 0.0 0.0027 16.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase AXE1 PF05448.12 KXL50338.1 - 0.0046 15.7 0.0 0.039 12.6 0.0 2.0 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Say1_Mug180 PF10340.9 KXL50338.1 - 0.16 10.8 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 Steryl acetyl hydrolase Zn_clus PF00172.18 KXL50339.1 - 8.9e-08 32.1 10.9 1.8e-07 31.2 10.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXL50339.1 - 0.00095 18.3 0.0 0.0042 16.1 0.0 2.1 1 1 1 2 2 2 1 Fungal specific transcription factor domain DUF3253 PF11625.8 KXL50340.1 - 1.9e-23 82.5 0.1 2.1e-23 82.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3253) TFIIS_C PF01096.18 KXL50341.1 - 0.013 15.4 3.5 0.031 14.1 3.5 1.7 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) Baculo_LEF5_C PF11792.8 KXL50341.1 - 0.57 9.9 3.2 0.33 10.7 0.3 2.1 2 1 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain RNA_pol_Rpb1_2 PF00623.20 KXL50342.1 - 0.00057 20.1 0.0 0.0011 19.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 DNA_pol_B PF00136.21 KXL50343.1 - 2.3e-15 56.3 0.2 2.9e-15 55.9 0.2 1.1 1 0 0 1 1 1 1 DNA polymerase family B 4HBT PF03061.22 KXL50343.1 - 0.082 13.3 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Thioesterase superfamily AAA_16 PF13191.6 KXL50344.1 - 0.0023 18.4 0.0 0.0054 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KXL50344.1 - 0.043 13.5 0.0 0.095 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KXL50344.1 - 0.055 14.0 0.1 0.13 12.8 0.1 1.5 1 0 0 1 1 1 0 ABC transporter AAA_21 PF13304.6 KXL50344.1 - 0.062 13.1 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 KXL50344.1 - 0.13 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 KXL50344.1 - 0.14 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_23 PF13476.6 KXL50344.1 - 0.19 12.2 0.0 0.45 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KXL50344.1 - 0.2 11.9 0.0 0.39 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Aa_trans PF01490.18 KXL50345.1 - 9.3e-15 54.2 30.3 4.9e-14 51.8 30.3 1.9 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein PBD PF00786.28 KXL50345.1 - 0.18 12.2 0.1 0.48 10.8 0.1 1.7 1 0 0 1 1 1 0 P21-Rho-binding domain MFS_1 PF07690.16 KXL50346.1 - 1.8e-58 198.2 22.5 3.4e-57 194.0 20.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL50346.1 - 5.7e-15 55.1 12.1 5.7e-15 55.1 12.1 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KXL50346.1 - 0.0031 15.9 5.6 0.044 12.1 3.5 2.8 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family LRR19-TM PF15176.6 KXL50346.1 - 0.0072 16.3 0.0 0.12 12.4 0.0 2.4 2 0 0 2 2 2 1 Leucine-rich repeat family 19 TM domain DUF2615 PF11027.8 KXL50346.1 - 0.012 15.7 0.3 3.7 7.7 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2615) OSTbeta PF15048.6 KXL50346.1 - 0.16 12.1 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein FAD_binding_4 PF01565.23 KXL50347.1 - 3.7e-27 94.8 7.4 7.8e-27 93.7 7.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXL50347.1 - 6.8e-09 35.7 1.1 1.3e-08 34.8 1.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like TFIID-31kDa PF02291.15 KXL50348.1 - 9e-33 112.9 0.0 1e-32 112.8 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Utp11 PF03998.13 KXL50349.1 - 6.6e-53 180.2 3.6 8e-53 179.9 3.6 1.1 1 0 0 1 1 1 1 Utp11 protein DUF501 PF04417.12 KXL50349.1 - 1.2 9.0 4.0 2.6 7.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF501) Fungal_trans PF04082.18 KXL50351.1 - 5.1e-09 35.5 2.4 9.8e-09 34.6 2.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL50351.1 - 6.5e-06 26.2 9.2 1.4e-05 25.1 9.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5447 PF17525.2 KXL50351.1 - 0.22 12.0 5.6 8.6 6.9 0.1 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5447) Sif PF06767.11 KXL50352.1 - 0.17 10.8 0.1 0.28 10.1 0.1 1.2 1 0 0 1 1 1 0 Sif protein Macoilin PF09726.9 KXL50352.1 - 9.6 4.6 6.1 12 4.2 6.1 1.1 1 0 0 1 1 1 0 Macoilin family Pyr_redox_2 PF07992.14 KXL50353.1 - 1.5e-33 116.3 0.0 1.5e-28 99.9 0.0 2.0 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXL50353.1 - 8.8e-12 45.4 0.3 4e-08 33.7 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXL50353.1 - 5.8e-09 35.6 0.0 2.5e-08 33.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXL50353.1 - 2.8e-05 23.9 0.0 0.16 11.6 0.0 3.1 4 0 0 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 KXL50353.1 - 0.00021 20.6 0.2 0.00057 19.1 0.1 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 KXL50353.1 - 0.0039 16.1 0.2 1.3 7.8 0.0 2.9 2 1 1 3 3 3 2 Tryptophan halogenase TrkA_N PF02254.18 KXL50353.1 - 0.0052 17.0 0.4 3.9 7.8 0.0 2.4 2 0 0 2 2 2 2 TrkA-N domain NAD_binding_8 PF13450.6 KXL50353.1 - 0.018 15.3 0.1 3.2 8.1 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXL50353.1 - 0.027 13.2 0.0 1.6 7.3 0.0 3.0 3 1 1 4 4 4 0 HI0933-like protein ThiF PF00899.21 KXL50353.1 - 0.098 12.0 0.2 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 ThiF family Lycopene_cycl PF05834.12 KXL50353.1 - 0.11 11.5 0.0 1.6 7.7 0.0 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein ECH_1 PF00378.20 KXL50354.1 - 1.2e-21 77.2 0.0 2e-20 73.2 0.0 2.3 2 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXL50354.1 - 2.2e-05 24.1 0.0 0.00072 19.1 0.0 2.3 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase Glyco_hydro_47 PF01532.20 KXL50355.1 - 4e-105 352.4 0.1 6e-105 351.8 0.0 1.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 47 NFRKB_winged PF14465.6 KXL50355.1 - 1.3 9.2 5.0 3.1 8.0 0.1 2.5 2 0 0 2 2 2 0 NFRKB Winged Helix-like PAP2 PF01569.21 KXL50356.1 - 3.6e-20 72.1 0.6 3.6e-20 72.1 0.6 2.0 2 0 0 2 2 2 1 PAP2 superfamily TPPK_C PF12555.8 KXL50356.1 - 0.015 15.4 6.2 1.2 9.3 0.1 3.4 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal DUF3671 PF12420.8 KXL50356.1 - 0.072 13.2 0.5 0.15 12.2 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function GPR_Gpa2_C PF11970.8 KXL50356.1 - 0.18 11.9 0.1 0.18 11.9 0.1 2.1 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term FAD_binding_3 PF01494.19 KXL50357.1 - 6.8e-71 239.3 0.0 8.4e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXL50357.1 - 6.1e-05 23.2 0.1 0.00014 22.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXL50357.1 - 0.0023 17.6 0.1 0.0036 17.0 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXL50357.1 - 0.0073 16.8 0.1 0.25 11.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXL50357.1 - 0.0086 15.3 0.0 0.017 14.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXL50357.1 - 0.0098 14.6 0.3 0.096 11.4 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 KXL50357.1 - 0.012 14.9 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXL50357.1 - 0.038 13.2 0.0 0.057 12.6 0.0 1.2 1 0 0 1 1 1 0 Thi4 family SE PF08491.10 KXL50357.1 - 0.12 11.4 0.1 0.35 9.9 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase DUF4050 PF13259.6 KXL50359.1 - 1.8e-41 142.5 6.7 4.6e-39 134.6 6.7 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF4050) Nfu_N PF08712.11 KXL50361.1 - 4.7e-29 100.3 0.0 5.4e-28 96.9 0.0 2.2 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 KXL50361.1 - 3e-27 94.6 0.1 4.8e-27 93.9 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain cobW PF02492.19 KXL50363.1 - 4e-33 114.5 0.0 4.9e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KXL50363.1 - 1.3e-07 30.9 0.7 1.6e-06 27.3 0.7 2.0 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 KXL50363.1 - 0.0026 18.3 0.0 0.0036 17.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KXL50363.1 - 0.0058 16.7 0.0 0.015 15.4 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATPase_2 PF01637.18 KXL50363.1 - 0.05 13.5 0.0 0.064 13.2 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TMEM51 PF15345.6 KXL50363.1 - 0.098 12.5 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 ResIII PF04851.15 KXL50363.1 - 0.1 12.6 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Raptor_N PF14538.6 KXL50366.1 - 1.4e-62 210.0 0.0 2.9e-62 209.0 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 KXL50366.1 - 3.6e-09 37.1 7.5 1.2 10.1 0.0 7.4 9 0 0 9 9 9 4 WD domain, G-beta repeat BBS2_Mid PF14783.6 KXL50366.1 - 2.7e-05 24.2 0.8 0.023 14.7 0.0 3.2 3 1 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region HEAT PF02985.22 KXL50366.1 - 0.00014 21.8 5.4 0.23 11.8 0.1 5.0 5 0 0 5 5 5 2 HEAT repeat SUIM_assoc PF16619.5 KXL50366.1 - 0.018 15.1 0.1 0.079 13.0 0.1 2.1 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Importin_rep_5 PF18816.1 KXL50366.1 - 0.11 12.8 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 Importin repeat p450 PF00067.22 KXL50367.1 - 1.9e-63 214.8 0.0 2.6e-63 214.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4538 PF15061.6 KXL50367.1 - 4 7.2 8.0 0.21 11.3 1.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) Metallophos PF00149.28 KXL50368.1 - 2.4e-11 44.5 4.9 8e-11 42.8 4.9 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXL50368.1 - 0.0016 18.7 0.8 0.0076 16.5 0.8 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain A_amylase_inhib PF01356.19 KXL50368.1 - 0.062 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Alpha amylase inhibitor Myb_DNA-binding PF00249.31 KXL50369.1 - 4.8e-16 58.7 0.1 2.4e-08 34.1 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXL50369.1 - 2.1e-12 47.1 0.0 8.6e-05 22.7 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 KXL50369.1 - 3.9e-05 23.7 0.1 0.38 10.8 0.0 2.7 2 1 0 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 KXL50369.1 - 0.17 12.1 0.0 0.4 10.9 0.0 1.6 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 PCI PF01399.27 KXL50370.1 - 4.3e-19 69.0 0.0 1.4e-18 67.3 0.0 1.9 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 KXL50370.1 - 4e-16 58.8 1.4 7.8e-16 57.9 1.4 1.5 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain TPR_20 PF14561.6 KXL50370.1 - 0.0073 16.6 2.1 0.025 14.9 0.4 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TetR_C_15 PF17918.1 KXL50370.1 - 0.77 10.5 7.9 19 6.1 0.2 3.6 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain UBX PF00789.20 KXL50371.1 - 4.6e-10 39.6 0.0 1.1e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 UBX domain Thioredoxin PF00085.20 KXL50371.1 - 0.0021 18.0 0.0 0.0052 16.7 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin TFIIA PF03153.13 KXL50371.1 - 0.0043 17.1 18.4 0.0043 17.1 18.4 1.6 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 KXL50371.1 - 0.084 11.6 9.4 0.11 11.2 9.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Herpes_DNAp_acc PF04929.12 KXL50371.1 - 0.38 9.7 7.1 0.56 9.1 7.1 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor GAGA_bind PF06217.12 KXL50371.1 - 0.67 10.2 12.6 1.2 9.4 12.6 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Macoilin PF09726.9 KXL50371.1 - 2.4 6.6 13.8 3.6 6.0 13.8 1.2 1 0 0 1 1 1 0 Macoilin family SURF1 PF02104.15 KXL50372.1 - 5.4e-44 150.5 0.0 6.9e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 SURF1 family UQ_con PF00179.26 KXL50374.1 - 2e-46 157.1 0.0 2.3e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXL50374.1 - 2.1e-05 24.3 0.0 2.7e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KXL50374.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.5 1 1 0 1 1 1 0 UEV domain fn3_2 PF16893.5 KXL50375.1 - 4.5e-37 126.1 0.0 8e-37 125.3 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 KXL50375.1 - 3e-24 84.7 0.3 5.4e-24 83.9 0.3 1.5 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 KXL50375.1 - 1.3e-15 57.1 0.0 2.7e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KXL50375.1 - 9.6e-10 38.7 0.0 2.1e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.8 KXL50375.1 - 4.4e-06 26.8 0.0 1.2e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) BRCT_2 PF16589.5 KXL50375.1 - 5.1e-05 23.6 0.0 0.00012 22.4 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain fn3 PF00041.21 KXL50375.1 - 0.0048 17.2 0.0 0.024 15.0 0.0 2.2 1 1 0 1 1 1 1 Fibronectin type III domain Fungal_trans_2 PF11951.8 KXL50376.1 - 3.8e-54 184.0 0.0 5.2e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain EutQ PF06249.12 KXL50376.1 - 8.8e-07 28.8 0.0 1.8e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Zn_clus PF00172.18 KXL50376.1 - 3.1e-06 27.2 11.8 5.6e-06 26.4 11.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cupin_3 PF05899.12 KXL50376.1 - 2.1e-05 24.1 0.0 4.4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 KXL50376.1 - 0.027 14.2 0.1 0.083 12.6 0.1 1.8 2 0 0 2 2 2 0 Cupin domain Methyltransf_3 PF01596.17 KXL50377.1 - 1.8e-31 109.0 0.0 2.3e-31 108.6 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KXL50377.1 - 2.6e-12 47.7 0.0 5.2e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KXL50377.1 - 4.1e-05 23.6 0.0 6.3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.12 KXL50377.1 - 0.001 18.8 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_31 PF13847.6 KXL50377.1 - 0.0023 17.7 0.0 0.018 14.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL50377.1 - 0.0059 17.3 0.0 0.017 15.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Romo1 PF10247.9 KXL50378.1 - 0.025 15.0 0.4 6.9 7.1 0.0 2.7 3 0 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 DUF1689 PF07954.11 KXL50378.1 - 0.072 13.5 0.0 0.09 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1689) Malate_synthase PF01274.22 KXL50379.1 - 5e-229 760.9 0.0 5.8e-229 760.7 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Sortilin-Vps10 PF15902.5 KXL50380.1 - 5.6e-297 984.5 10.1 9.5e-156 519.0 3.5 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KXL50380.1 - 2.5e-93 311.1 20.8 8.8e-48 162.9 7.9 2.3 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 KXL50380.1 - 1.1e-13 49.0 31.9 0.95 9.7 0.1 11.4 10 0 0 10 10 10 6 BNR/Asp-box repeat PSII_BNR PF14870.6 KXL50380.1 - 7.2e-06 25.5 5.7 0.0071 15.6 0.2 4.5 4 1 0 4 4 4 2 Photosynthesis system II assembly factor YCF48 CHB_HEX_C PF03174.13 KXL50380.1 - 0.0093 15.9 7.0 0.26 11.3 0.0 5.8 7 0 0 7 7 7 1 Chitobiase/beta-hexosaminidase C-terminal domain Inhibitor_I66 PF16850.5 KXL50380.1 - 0.02 14.8 0.4 0.074 12.9 0.0 2.2 2 0 0 2 2 2 0 Peptidase inhibitor I66 DUF2561 PF10812.8 KXL50380.1 - 0.041 13.9 0.1 0.076 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) DUF2122 PF09895.9 KXL50380.1 - 0.072 13.5 0.0 7.3 7.0 0.0 3.1 3 0 0 3 3 3 0 RecB-family nuclease (DUF2122) POC3_POC4 PF10448.9 KXL50380.1 - 0.077 13.0 0.1 0.46 10.5 0.1 2.3 2 0 0 2 2 2 0 20S proteasome chaperone assembly proteins 3 and 4 Cys_knot PF00007.22 KXL50380.1 - 2.8 8.3 11.6 7.9 6.8 1.3 2.7 2 0 0 2 2 2 0 Cystine-knot domain Sugar-bind PF04198.13 KXL50381.1 - 0.018 14.2 0.0 0.019 14.1 0.0 1.0 1 0 0 1 1 1 0 Putative sugar-binding domain GPI-anchored PF10342.9 KXL50382.1 - 1.6e-21 76.9 2.3 1.6e-21 76.9 2.3 2.3 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SOG2 PF10428.9 KXL50382.1 - 6.6 5.8 24.9 8.1 5.5 24.9 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein F-box-like PF12937.7 KXL50384.1 - 3.5e-06 26.8 0.0 7e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like LRR_2 PF07723.13 KXL50384.1 - 2 9.2 0.0 2 9.2 0.0 4.1 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_4 PF12799.7 KXL50384.1 - 3.1 8.3 5.5 48 4.6 0.2 3.9 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) GPI-anchored PF10342.9 KXL50386.1 - 1.5e-11 44.9 0.7 2.8e-11 44.0 0.7 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family COesterase PF00135.28 KXL50387.1 - 1.4e-76 258.5 0.1 2.5e-76 257.6 0.1 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXL50387.1 - 8.3e-11 42.1 0.1 8.3e-10 38.9 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXL50387.1 - 0.0088 15.5 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Methyltransf_25 PF13649.6 KXL50388.1 - 9.3e-11 42.3 0.0 1.7e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL50388.1 - 3.2e-10 40.5 0.0 6.2e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL50388.1 - 1.4e-07 32.2 0.0 2e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXL50388.1 - 3.7e-07 30.1 0.0 6.1e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL50388.1 - 8.1e-07 28.9 0.0 1.7e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXL50388.1 - 7.5e-05 22.2 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Met_10 PF02475.16 KXL50389.1 - 1.7e-67 227.1 0.0 2.2e-67 226.7 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Kinesin PF00225.23 KXL50390.1 - 1.3e-111 372.7 0.0 2e-111 372.1 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.8 KXL50390.1 - 1.4e-37 129.7 0.0 4.5e-37 128.1 0.0 1.9 1 0 0 1 1 1 1 Kinesin protein Kinesin_assoc PF16183.5 KXL50390.1 - 8.5e-37 127.0 8.5 2.3e-29 102.8 0.1 3.4 2 1 1 3 3 3 2 Kinesin-associated Microtub_bd PF16796.5 KXL50390.1 - 2.3e-25 89.3 0.0 1.2e-24 86.9 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding FHA PF00498.26 KXL50390.1 - 0.00048 20.4 0.2 0.0022 18.3 0.1 2.2 2 0 0 2 2 2 1 FHA domain KIF1B PF12423.8 KXL50390.1 - 0.35 11.3 2.7 0.39 11.2 0.8 2.2 2 0 0 2 2 2 0 Kinesin protein 1B UPF0242 PF06785.11 KXL50390.1 - 0.5 10.4 17.0 0.77 9.8 1.5 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4515 PF14988.6 KXL50390.1 - 2.1 8.2 24.7 0.042 13.7 12.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) Rab5-bind PF09311.11 KXL50390.1 - 4.8 6.5 16.3 1.6 8.0 9.5 2.3 2 0 0 2 2 2 0 Rabaptin-like protein Vir_act_alpha_C PF10400.9 KXL50390.1 - 8.3 7.2 19.5 1.8 9.3 1.3 4.4 3 1 1 4 4 4 0 Virulence activator alpha C-term MFS_1 PF07690.16 KXL50392.1 - 1.4e-14 53.8 16.8 1.4e-14 53.8 16.8 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL50392.1 - 0.00019 20.4 2.6 0.00019 20.4 2.6 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter Adeno_PV PF03910.13 KXL50392.1 - 0.055 12.2 0.1 0.084 11.6 0.1 1.2 1 0 0 1 1 1 0 Adenovirus minor core protein PV HAMP_N3 PF18575.1 KXL50392.1 - 0.17 11.4 0.0 0.37 10.4 0.0 1.5 1 0 0 1 1 1 0 HAMP N-terminal domain 3 DASH_Hsk3 PF08227.11 KXL50393.1 - 3.1e-19 69.0 4.0 3.9e-19 68.7 4.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like BBS2_C PF14782.6 KXL50393.1 - 0.053 12.3 0.0 0.06 12.1 0.0 1.0 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal ICL PF00463.21 KXL50395.1 - 4.1e-195 649.3 0.0 4.7e-195 649.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KXL50395.1 - 1.4e-09 37.8 0.1 1.6e-08 34.4 0.0 2.1 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Citrate_synt PF00285.21 KXL50396.1 - 1.7e-99 333.3 0.0 2e-99 333.1 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain adh_short_C2 PF13561.6 KXL50397.1 - 2.1e-42 145.3 0.0 2.4e-42 145.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL50397.1 - 9.6e-35 119.8 0.0 1.3e-34 119.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL50397.1 - 0.0072 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Herpes_UL6 PF01763.16 KXL50397.1 - 0.1 11.1 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like AAA PF00004.29 KXL50398.1 - 2.5e-51 173.6 0.0 2.2e-43 147.8 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXL50398.1 - 1.9e-05 25.1 0.4 0.0082 16.5 0.0 3.7 3 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KXL50398.1 - 0.00012 21.9 0.0 0.00037 20.3 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXL50398.1 - 0.0011 19.3 0.5 0.014 15.7 0.0 3.1 3 1 1 4 4 2 1 AAA domain Parvo_NS1 PF01057.17 KXL50398.1 - 0.0014 17.8 0.0 0.0026 16.9 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 KXL50398.1 - 0.0016 18.8 0.0 0.014 15.8 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.14 KXL50398.1 - 0.002 18.1 0.0 0.018 15.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 KXL50398.1 - 0.0022 17.8 6.6 0.02 14.7 0.1 2.9 3 0 0 3 3 2 1 AAA+ lid domain TIP49 PF06068.13 KXL50398.1 - 0.0027 17.0 0.0 0.0056 15.9 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 KXL50398.1 - 0.0035 17.1 0.0 0.0079 15.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 KXL50398.1 - 0.0037 16.9 0.1 0.017 14.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 KXL50398.1 - 0.0067 15.8 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_2 PF07724.14 KXL50398.1 - 0.0075 16.4 0.0 0.021 14.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KXL50398.1 - 0.011 16.2 0.0 0.033 14.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KXL50398.1 - 0.017 15.1 0.0 0.049 13.6 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 KXL50398.1 - 0.021 14.2 0.1 0.043 13.2 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Y2_Tnp PF04986.13 KXL50398.1 - 0.034 14.2 0.1 0.071 13.2 0.1 1.4 1 0 0 1 1 1 0 Putative transposase AAA_7 PF12775.7 KXL50398.1 - 0.034 13.7 0.0 0.074 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 KXL50398.1 - 0.038 14.0 0.0 0.41 10.7 0.0 2.5 3 0 0 3 3 2 0 AAA domain Vps4_C PF09336.10 KXL50398.1 - 0.059 13.4 0.1 0.18 11.8 0.1 1.9 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain PhoH PF02562.16 KXL50398.1 - 0.075 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.6 KXL50398.1 - 0.088 12.5 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXL50398.1 - 0.098 12.8 0.0 0.86 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KXL50398.1 - 0.1 11.8 0.0 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.6 KXL50398.1 - 0.13 12.5 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Abhydro_lipase PF04083.16 KXL50399.1 - 1.6e-19 69.2 0.0 3.9e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 KXL50399.1 - 7.6e-09 35.6 0.0 1.6e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXL50399.1 - 0.00011 21.6 0.0 0.0002 20.7 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF5481 PF17578.2 KXL50400.1 - 0.1 13.0 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5481) p450 PF00067.22 KXL50402.1 - 1.6e-95 320.5 0.0 1.9e-95 320.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NDUFB10 PF10249.9 KXL50403.1 - 0.0015 19.0 0.0 0.0017 18.9 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 HWE_HK PF07536.14 KXL50403.1 - 0.06 14.0 0.0 0.098 13.4 0.0 1.3 1 0 0 1 1 1 0 HWE histidine kinase WD40 PF00400.32 KXL50404.1 - 4.8e-13 49.4 2.4 0.18 12.7 0.2 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL50404.1 - 0.0032 17.7 0.1 3.4 8.0 0.0 3.5 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain 60KD_IMP PF02096.20 KXL50405.1 - 0.0044 16.9 0.1 0.0081 16.1 0.0 1.5 2 0 0 2 2 2 1 60Kd inner membrane protein DUF1217 PF06748.12 KXL50405.1 - 0.12 12.4 0.1 0.41 10.7 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1217) Peptidase_S49 PF01343.18 KXL50405.1 - 0.18 11.8 0.2 0.28 11.1 0.2 1.3 1 0 0 1 1 1 0 Peptidase family S49 OPT PF03169.15 KXL50406.1 - 6.5e-131 438.0 47.8 7.3e-131 437.8 47.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CorA PF01544.18 KXL50408.1 - 3.6e-11 42.9 0.2 1.1e-10 41.3 0.0 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein CEBP1_N PF16368.5 KXL50408.1 - 0.013 15.0 0.1 0.036 13.6 0.0 1.8 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein 1 N-terminus Zn_clus PF00172.18 KXL50409.1 - 7.5e-07 29.2 10.4 1.2e-06 28.5 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXL50409.1 - 3.8e-05 22.9 0.2 7.2e-05 21.9 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PdxA PF04166.12 KXL50410.1 - 2.5e-80 269.9 0.1 3.1e-80 269.6 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA Iso_dh PF00180.20 KXL50410.1 - 0.094 11.8 0.1 0.2 10.8 0.1 1.5 1 0 0 1 1 1 0 Isocitrate/isopropylmalate dehydrogenase Lactamase_B PF00753.27 KXL50411.1 - 0.00036 20.6 6.9 0.0072 16.4 7.0 3.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXL50411.1 - 0.03 13.8 0.0 0.067 12.7 0.0 1.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain MFS_1 PF07690.16 KXL50412.1 - 1.9e-38 132.3 22.1 7.6e-38 130.3 22.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Ank PF00023.30 KXL50413.1 - 2.1e-11 43.7 0.3 4.5e-06 26.9 0.0 2.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KXL50413.1 - 5.4e-10 39.7 0.0 7e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXL50413.1 - 4.8e-09 35.7 0.0 0.0014 19.0 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KXL50413.1 - 1.8e-07 31.6 0.0 2.9e-07 30.9 0.0 1.4 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXL50413.1 - 2.1e-07 31.1 0.0 2.6e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) PEGA PF08308.11 KXL50413.1 - 0.041 13.8 0.0 0.49 10.3 0.0 2.1 2 0 0 2 2 2 0 PEGA domain DUF2773 PF10971.8 KXL50413.1 - 0.077 13.1 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2773) DUF2496 PF10689.9 KXL50414.1 - 0.22 11.4 4.2 1.3 8.9 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2496) DUF3435 PF11917.8 KXL50415.1 - 5.9e-30 104.5 0.7 7.6e-30 104.2 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) DUF3435 PF11917.8 KXL50416.1 - 7.5e-47 160.2 2.6 2.9e-30 105.6 1.0 4.0 2 1 1 3 3 3 3 Protein of unknown function (DUF3435) DAHP_synth_1 PF00793.20 KXL50417.1 - 6.9e-101 336.7 0.0 8.7e-101 336.4 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family FKBP_C PF00254.28 KXL50418.1 - 4.1e-24 84.7 0.0 4.8e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PHP PF02811.19 KXL50419.1 - 7.6e-13 49.1 0.0 1.1e-12 48.5 0.0 1.3 1 0 0 1 1 1 1 PHP domain Pkinase PF00069.25 KXL50420.1 - 3.2e-73 246.3 0.0 4e-73 246.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL50420.1 - 2.2e-36 125.5 0.0 2.8e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KXL50420.1 - 1.5e-15 57.3 0.0 3.6e-15 56.1 0.0 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 KXL50420.1 - 5.7e-10 39.0 0.0 9.5e-09 35.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KXL50420.1 - 1.6e-05 23.9 0.0 3.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 KXL50420.1 - 7.2e-05 23.0 0.0 0.00014 22.1 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 KXL50420.1 - 0.0047 16.3 0.0 0.0079 15.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PNP_phzG_C PF10590.9 KXL50421.1 - 2e-18 66.2 6.2 2e-18 66.2 6.2 1.8 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 KXL50421.1 - 2.1e-18 66.3 0.0 3.5e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 KXL50421.1 - 0.00066 20.2 0.1 0.0012 19.4 0.1 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase UPF0086 PF01868.16 KXL50422.1 - 9.6e-27 92.7 1.7 1.3e-26 92.3 1.7 1.2 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Pam17 PF08566.10 KXL50423.1 - 1.7e-59 200.3 0.1 1.9e-59 200.2 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 UCR_Fe-S_N PF10399.9 KXL50423.1 - 0.0024 17.2 0.2 0.0024 17.2 0.2 2.3 2 0 0 2 2 2 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal ADH_zinc_N PF00107.26 KXL50424.1 - 1.1e-20 73.9 0.9 2.6e-20 72.7 0.9 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXL50424.1 - 6e-17 61.5 2.3 6e-17 61.5 2.3 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Methyltransf_32 PF13679.6 KXL50424.1 - 0.016 15.2 0.3 0.041 13.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain ADH_zinc_N_2 PF13602.6 KXL50424.1 - 0.05 14.7 0.1 0.095 13.8 0.1 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Lipocalin_5 PF13924.6 KXL50425.1 - 1.3e-16 60.7 0.0 1.4e-16 60.5 0.0 1.0 1 0 0 1 1 1 1 Lipocalin-like domain RRS1 PF04939.12 KXL50426.1 - 6.9e-51 172.3 1.8 7.7e-51 172.2 1.8 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) AMP-binding PF00501.28 KXL50427.1 - 3.8e-102 342.0 0.0 4.4e-102 341.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXL50427.1 - 3.1e-15 56.9 0.6 1.3e-14 54.9 0.1 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DSPc PF00782.20 KXL50428.1 - 4.1e-25 88.1 0.0 5.8e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KXL50428.1 - 0.016 15.5 0.0 0.028 14.7 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain ANTAR PF03861.14 KXL50428.1 - 0.022 14.6 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 ANTAR domain Yippee-Mis18 PF03226.14 KXL50428.1 - 0.053 13.7 1.0 0.13 12.5 1.0 1.7 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Y_phosphatase3 PF13350.6 KXL50428.1 - 0.054 13.5 0.0 0.072 13.0 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KXL50429.1 - 3.6e-40 137.2 0.0 4.3e-40 137.0 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KXL50429.1 - 2e-07 31.2 0.0 3.2e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KXL50429.1 - 3.3e-05 23.7 0.0 4.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXL50429.1 - 0.0066 16.1 0.0 0.0082 15.7 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Ras PF00071.22 KXL50431.1 - 3.7e-55 185.9 0.0 4.3e-55 185.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXL50431.1 - 7.2e-22 77.9 0.0 1.1e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXL50431.1 - 2e-06 27.4 0.0 3.3e-06 26.7 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KXL50431.1 - 0.0016 17.9 0.0 0.0027 17.2 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KXL50431.1 - 0.04 13.7 0.1 4.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 KXL50431.1 - 0.044 13.0 0.1 0.43 9.7 0.0 2.0 1 1 1 2 2 2 0 NB-ARC domain Gtr1_RagA PF04670.12 KXL50431.1 - 0.14 11.5 0.0 0.16 11.3 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF647 PF04884.14 KXL50432.1 - 1.6e-109 365.1 1.4 2.3e-109 364.7 1.4 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Mntp PF02659.15 KXL50432.1 - 0.043 13.6 0.1 0.19 11.5 0.1 2.1 2 0 0 2 2 2 0 Putative manganese efflux pump CorA PF01544.18 KXL50433.1 - 0.0006 19.2 9.2 0.0019 17.6 9.1 1.9 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Kelch_5 PF13854.6 KXL50434.1 - 1.7e-12 47.0 2.6 4.8e-12 45.6 0.7 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.6 KXL50434.1 - 5.7e-09 35.8 1.8 8.5e-07 28.9 0.1 2.7 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.6 KXL50434.1 - 3e-05 24.2 0.3 8.1e-05 22.8 0.3 1.7 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_1 PF01344.25 KXL50434.1 - 6.7e-05 22.4 3.6 0.023 14.3 0.1 2.7 2 0 0 2 2 2 2 Kelch motif RAG2 PF03089.14 KXL50434.1 - 0.0049 15.9 0.1 0.014 14.4 0.1 1.6 1 1 0 1 1 1 1 Recombination activating protein 2 Kelch_6 PF13964.6 KXL50434.1 - 0.077 13.3 2.3 0.55 10.6 0.3 2.5 2 0 0 2 2 2 0 Kelch motif Kelch_2 PF07646.15 KXL50434.1 - 0.12 12.4 1.0 3.9 7.6 0.0 2.7 2 0 0 2 2 2 0 Kelch motif Brix PF04427.18 KXL50435.1 - 2.7e-32 112.4 0.0 3.5e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Brix domain Histidinol_dh PF00815.20 KXL50437.1 - 1.5e-139 465.5 0.0 1.8e-139 465.3 0.0 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase Formyl_trans_N PF00551.19 KXL50440.1 - 1.7e-40 138.7 0.0 2.2e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase YabP PF07873.11 KXL50440.1 - 0.081 12.7 0.1 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 YabP family zf-C2H2_10 PF16588.5 KXL50441.1 - 0.015 15.0 0.9 0.027 14.2 0.9 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger Retrotran_gag_2 PF14223.6 KXL50441.1 - 0.055 13.1 0.1 0.09 12.4 0.1 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DDE_1 PF03184.19 KXL50442.1 - 6.8e-06 25.8 0.0 6.9e-06 25.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KXL50442.1 - 0.025 14.3 0.2 0.027 14.2 0.2 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease DEAD PF00270.29 KXL50445.1 - 1.2e-27 96.8 0.0 2.1e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 KXL50445.1 - 4.1e-20 72.3 2.1 1e-19 71.0 2.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 KXL50445.1 - 2.1e-13 50.6 0.1 5.7e-12 46.0 0.1 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CDT1 PF08839.11 KXL50445.1 - 1.2e-07 32.1 0.3 2.2e-07 31.3 0.3 1.4 1 0 0 1 1 1 1 DNA replication factor CDT1 like ResIII PF04851.15 KXL50445.1 - 4.6e-06 26.8 0.0 8.4e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Peptidase_M16 PF00675.20 KXL50447.1 - 1e-57 194.3 0.4 2.6e-57 193.0 0.4 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KXL50447.1 - 1.9e-36 125.8 0.0 7.8e-36 123.8 0.0 2.0 3 0 0 3 3 3 1 Peptidase M16 inactive domain CybS PF05328.12 KXL50448.1 - 1.2e-44 151.2 0.0 1.5e-44 150.9 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Acetyltransf_7 PF13508.7 KXL50449.1 - 3.3e-05 24.2 0.1 3.7e-05 24.1 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXL50449.1 - 0.0081 16.1 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXL50449.1 - 0.022 15.0 0.0 0.041 14.1 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family UDG PF03167.19 KXL50450.1 - 1e-17 64.5 0.0 1.4e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily ApbA_C PF08546.11 KXL50451.1 - 1.1e-29 103.1 0.1 2e-29 102.3 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KXL50451.1 - 7.4e-27 93.9 0.0 1.2e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA AAL_decarboxy PF03306.13 KXL50452.1 - 2.9e-33 115.0 0.1 2.7e-19 69.4 0.0 2.0 1 1 1 2 2 2 2 Alpha-acetolactate decarboxylase T5orf172 PF10544.9 KXL50453.1 - 1.5e-11 44.7 0.2 1.5e-11 44.7 0.2 2.4 2 1 1 3 3 3 1 T5orf172 domain T5orf172 PF10544.9 KXL50454.1 - 9.2e-12 45.4 0.1 3e-11 43.7 0.1 1.9 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 KXL50454.1 - 1.1e-07 32.4 0.3 3.2e-07 30.9 0.1 2.0 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 DUF4233 PF14017.6 KXL50454.1 - 0.11 12.8 1.6 0.21 11.9 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4233) ACPS PF01648.20 KXL50455.1 - 3.5e-12 46.5 0.0 1.2e-11 44.7 0.0 1.9 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 KXL50455.1 - 0.14 12.3 0.0 9.9 6.4 0.0 2.3 2 0 0 2 2 2 0 4'-phosphopantetheinyl transferase N-terminal domain Adaptin_N PF01602.20 KXL50456.1 - 1.3e-117 393.5 8.9 1.7e-117 393.2 8.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KXL50456.1 - 1.2e-54 184.8 7.1 1.4e-54 184.5 0.5 3.1 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXL50456.1 - 1.1e-14 54.5 7.2 1.7e-08 34.7 0.3 4.4 4 0 0 4 4 4 3 HEAT repeats HEAT PF02985.22 KXL50456.1 - 1.3e-10 40.5 2.1 0.011 15.9 0.0 5.6 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.6 KXL50456.1 - 0.00029 21.3 1.9 9.8 6.8 0.0 5.2 5 0 0 5 5 5 2 HEAT-like repeat CLASP_N PF12348.8 KXL50456.1 - 0.0004 20.0 0.6 0.67 9.5 0.0 3.0 2 0 0 2 2 2 2 CLASP N terminal DNA_alkylation PF08713.11 KXL50456.1 - 0.0095 15.7 0.9 14 5.4 0.0 3.6 3 2 2 5 5 5 1 DNA alkylation repair enzyme RTP1_C1 PF10363.9 KXL50456.1 - 0.019 15.1 3.1 0.44 10.8 0.1 3.4 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 YscJ_FliF PF01514.17 KXL50456.1 - 0.043 13.5 0.1 0.087 12.5 0.1 1.4 1 0 0 1 1 1 0 Secretory protein of YscJ/FliF family Arm PF00514.23 KXL50456.1 - 0.048 13.7 4.1 52 4.1 0.0 5.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 KXL50456.1 - 0.063 13.3 0.0 29 4.8 0.0 4.2 4 1 1 5 5 5 0 Spinocerebellar ataxia type 10 protein domain RICTOR_N PF14664.6 KXL50456.1 - 0.086 11.8 7.1 6.2 5.7 0.1 3.8 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, N-term DUF1077 PF06417.12 KXL50457.1 - 3.2e-50 169.1 2.2 4.1e-50 168.7 2.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) NOG1_N PF17835.1 KXL50458.1 - 2.1e-48 164.3 1.3 3.7e-48 163.5 0.0 2.1 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOG1 PF06858.14 KXL50458.1 - 8.3e-26 89.5 0.4 1.9e-25 88.4 0.4 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 KXL50458.1 - 1.1e-25 89.3 1.9 2.8e-25 88.0 1.9 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 KXL50458.1 - 4.6e-14 52.5 0.0 9.5e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXL50458.1 - 8.4e-08 31.9 0.0 1.8e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KXL50458.1 - 0.00043 20.2 0.5 0.12 12.3 0.1 3.0 3 1 0 3 3 3 1 RsgA GTPase Gtr1_RagA PF04670.12 KXL50458.1 - 0.00047 19.6 0.1 0.00083 18.8 0.1 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_18 PF13238.6 KXL50458.1 - 0.068 13.7 0.3 0.3 11.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KXL50458.1 - 0.14 12.4 0.1 0.98 9.7 0.0 2.3 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KXL50458.1 - 0.94 9.5 8.3 5.1 7.1 0.0 3.5 3 1 1 4 4 4 0 Dynamin family HTH_Tnp_Tc5 PF03221.16 KXL50459.1 - 0.0046 17.0 0.2 0.0088 16.1 0.2 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Csm1 PF12539.8 KXL50460.1 - 1.7e-33 115.1 0.1 3.8e-33 114.0 0.0 1.7 2 0 0 2 2 1 1 Chromosome segregation protein Csm1/Pcs1 Filament PF00038.21 KXL50460.1 - 8.6e-05 22.3 13.0 8.6e-05 22.3 13.0 1.8 2 1 0 2 2 1 1 Intermediate filament protein Rootletin PF15035.6 KXL50460.1 - 0.004 17.2 14.7 0.0092 16.0 14.7 1.6 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion GAS PF13851.6 KXL50460.1 - 0.097 12.0 24.5 0.38 10.1 24.5 2.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding PRKG1_interact PF15898.5 KXL50460.1 - 0.12 13.3 27.6 0.11 13.5 5.3 3.0 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain Cep57_CLD_2 PF14197.6 KXL50460.1 - 0.14 12.3 10.8 0.037 14.1 5.6 2.6 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Spc7 PF08317.11 KXL50460.1 - 0.15 10.9 22.2 0.99 8.2 21.9 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF5082 PF16888.5 KXL50460.1 - 0.39 11.0 15.3 1.7 8.9 4.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) ADIP PF11559.8 KXL50460.1 - 0.42 10.7 23.0 0.079 13.0 15.2 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Matrilin_ccoil PF10393.9 KXL50460.1 - 0.62 10.0 3.4 34 4.4 0.1 3.4 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin MAD PF05557.13 KXL50460.1 - 0.71 8.2 21.6 12 4.1 22.1 2.0 1 1 0 1 1 1 0 Mitotic checkpoint protein DUF2968 PF11180.8 KXL50460.1 - 0.84 9.2 13.9 0.083 12.5 6.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF4763 PF15960.5 KXL50460.1 - 1 8.6 10.8 0.31 10.3 6.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) AIP3 PF03915.13 KXL50460.1 - 1.4 7.9 16.7 0.09 11.9 11.3 1.7 2 0 0 2 2 2 0 Actin interacting protein 3 Jnk-SapK_ap_N PF09744.9 KXL50460.1 - 2.2 8.5 21.2 4.7 7.4 15.5 2.8 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 YabA PF06156.13 KXL50460.1 - 2.6 8.7 16.4 4 8.1 7.5 3.3 1 1 1 2 2 2 0 Initiation control protein YabA HAUS-augmin3 PF14932.6 KXL50460.1 - 3.1 7.3 22.9 5.7 6.4 11.8 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 FUSC PF04632.12 KXL50460.1 - 3.2 6.2 3.6 12 4.3 3.5 1.5 1 1 1 2 2 2 0 Fusaric acid resistance protein family Lebercilin PF15619.6 KXL50460.1 - 3.6 7.2 23.1 0.87 9.2 5.5 2.5 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease COG2 PF06148.11 KXL50460.1 - 3.7 7.6 8.1 0.66 10.1 2.1 2.4 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TSC22 PF01166.18 KXL50460.1 - 4.7 7.6 6.0 0.72 10.2 0.1 2.6 2 1 1 3 3 3 0 TSC-22/dip/bun family DUF2937 PF11157.8 KXL50460.1 - 5.5 6.7 5.7 1.9 8.2 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Hamartin PF04388.12 KXL50460.1 - 6.9 5.2 22.6 9.5 4.7 22.6 1.3 1 1 0 1 1 1 0 Hamartin protein DUF4407 PF14362.6 KXL50460.1 - 7.3 5.8 22.0 0.095 12.0 13.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Golgin_A5 PF09787.9 KXL50460.1 - 9.7 5.6 18.7 1.1 8.6 7.8 2.1 1 1 0 1 1 1 0 Golgin subfamily A member 5 Glyco_hydro_2_N PF02837.18 KXL50461.1 - 4.5e-12 46.2 0.0 1.9e-11 44.1 0.0 2.0 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 KXL50461.1 - 3.1e-10 39.7 0.1 1.1e-08 34.6 0.1 2.6 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 KXL50461.1 - 3e-08 34.3 0.0 7e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Acetyltransf_1 PF00583.25 KXL50462.1 - 5.3e-13 49.2 0.0 9.5e-13 48.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXL50462.1 - 9.8e-13 48.2 0.0 1.5e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXL50462.1 - 8.9e-11 42.1 0.0 1.3e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXL50462.1 - 2.7e-06 27.5 0.0 5.1e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXL50462.1 - 0.0031 17.4 0.0 0.006 16.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 KXL50462.1 - 0.021 15.0 0.0 0.05 13.7 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_16 PF05301.11 KXL50462.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 Acetyltransf_CG PF14542.6 KXL50462.1 - 0.15 12.2 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase ubiquitin PF00240.23 KXL50463.1 - 2.1e-06 27.4 0.0 3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 KXL50463.1 - 0.077 13.7 0.1 0.23 12.2 0.1 2.0 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Fe-ADH PF00465.19 KXL50464.1 - 5.4e-63 213.0 0.0 6.9e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KXL50464.1 - 1e-08 35.2 0.0 1.4e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fungal_trans_2 PF11951.8 KXL50467.1 - 7.5e-14 51.3 0.2 9.9e-10 37.8 1.2 2.8 2 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL50467.1 - 1.3e-07 31.6 10.0 2.4e-07 30.8 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rhomboid_SP PF12595.8 KXL50467.1 - 0.081 12.3 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Rhomboid serine protease Sugar_tr PF00083.24 KXL50468.1 - 3.7e-69 233.7 26.0 4.4e-69 233.5 26.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL50468.1 - 2e-13 50.0 25.3 2e-13 50.0 25.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL50469.1 - 3.3e-110 369.1 17.7 3.9e-110 368.8 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL50469.1 - 2.8e-25 89.0 28.1 5.7e-25 88.0 22.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 KXL50469.1 - 0.019 13.9 4.0 0.018 14.0 2.2 1.8 2 0 0 2 2 2 0 Sugar-tranasporters, 12 TM HTH_Tnp_Tc5 PF03221.16 KXL50470.1 - 4.7e-05 23.3 0.1 0.00013 21.9 0.0 1.7 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 KXL50470.1 - 0.0005 19.7 0.3 0.00074 19.2 0.3 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.6 KXL50470.1 - 0.0022 17.8 0.1 0.83 9.5 0.0 3.4 3 1 1 4 4 4 1 Homeodomain-like domain HTH_28 PF13518.6 KXL50470.1 - 0.0063 16.6 0.1 0.27 11.4 0.0 3.1 3 1 1 4 4 4 1 Helix-turn-helix domain HeLo PF14479.6 KXL50472.1 - 1.1e-23 84.2 0.3 1.1e-23 84.1 0.3 1.0 1 0 0 1 1 1 1 Prion-inhibition and propagation ANAPC5 PF12862.7 KXL50472.1 - 0.11 12.6 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 HeLo PF14479.6 KXL50473.1 - 4e-09 36.6 0.1 4e-09 36.6 0.1 1.0 1 0 0 1 1 1 1 Prion-inhibition and propagation DDE_1 PF03184.19 KXL50476.1 - 9.1e-05 22.2 0.0 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease YppG PF14179.6 KXL50477.1 - 0.034 14.8 0.4 0.059 14.1 0.4 1.4 1 0 0 1 1 1 0 YppG-like protein adh_short_C2 PF13561.6 KXL50478.1 - 8.7e-48 162.9 5.4 1.5e-39 135.9 2.8 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL50478.1 - 9.1e-43 146.0 3.6 1.2e-42 145.6 3.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL50478.1 - 4.4e-14 52.8 0.5 6.8e-14 52.2 0.5 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KXL50478.1 - 0.0023 17.8 0.8 0.004 17.1 0.8 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KXL50478.1 - 0.006 16.7 0.2 0.01 15.9 0.2 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain THF_DHG_CYH_C PF02882.19 KXL50478.1 - 0.011 15.0 0.3 0.056 12.8 0.2 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain UDPG_MGDP_dh_N PF03721.14 KXL50478.1 - 0.1 12.1 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UFD1 PF03152.14 KXL50479.1 - 1.2e-28 99.8 0.0 4e-15 55.7 0.0 3.7 3 1 1 4 4 4 3 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 KXL50479.1 - 1.6e-06 28.3 0.2 7.7e-06 26.1 0.2 2.2 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A zf_UBZ PF18439.1 KXL50479.1 - 0.34 10.5 4.1 2.5 7.8 0.1 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 KXL50479.1 - 0.38 10.5 2.8 2 8.2 0.1 3.0 2 0 0 2 2 2 0 zinc-finger C2H2-type zinc_ribbon_4 PF13717.6 KXL50479.1 - 1 9.4 8.5 1.7 8.6 0.1 3.7 4 0 0 4 4 4 0 zinc-ribbon domain zf-TRAF PF02176.18 KXL50479.1 - 3.2 8.5 19.9 0.77 10.5 1.6 4.0 4 0 0 4 4 4 0 TRAF-type zinc finger zf-C2H2 PF00096.26 KXL50479.1 - 5.6 7.6 20.9 0.95 10.0 0.2 5.1 5 0 0 5 5 5 0 Zinc finger, C2H2 type GST_N_3 PF13417.6 KXL50481.1 - 0.0015 18.9 0.0 0.0022 18.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXL50481.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.6 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain ADH_zinc_N PF00107.26 KXL50482.1 - 2.1e-05 24.5 1.2 3.1e-05 23.9 0.1 1.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase 4HBT PF03061.22 KXL50483.1 - 9.1e-10 38.8 0.0 1e-07 32.2 0.0 2.7 3 0 0 3 3 3 2 Thioesterase superfamily adh_short_C2 PF13561.6 KXL50484.1 - 8.8e-50 169.4 0.0 1e-49 169.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL50484.1 - 5.1e-47 159.9 0.0 6.3e-47 159.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL50484.1 - 8.4e-11 42.1 0.0 1.1e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL50484.1 - 5.5e-06 26.0 0.0 8.9e-06 25.3 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXL50484.1 - 6.5e-05 22.5 0.0 0.00013 21.5 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXL50484.1 - 0.0076 15.4 0.0 0.0087 15.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KXL50484.1 - 0.038 13.9 0.0 0.074 12.9 0.0 1.5 1 1 0 1 1 1 0 NAD(P)H-binding ABC_tran PF00005.27 KXL50485.1 - 3.8e-33 114.9 0.0 7.5e-33 114.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KXL50485.1 - 5e-24 85.4 4.9 5e-24 85.4 4.9 1.9 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 KXL50485.1 - 0.00022 20.7 0.4 0.0029 17.1 0.0 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KXL50485.1 - 0.0052 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 KXL50485.1 - 0.018 15.5 0.3 0.16 12.4 0.3 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 KXL50485.1 - 0.019 14.8 1.2 0.4 10.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system PBP1_TM PF14812.6 KXL50485.1 - 0.037 14.4 1.8 0.083 13.3 1.8 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AAA_22 PF13401.6 KXL50485.1 - 0.038 14.3 0.5 0.42 10.9 0.5 2.3 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXL50485.1 - 0.077 13.4 0.2 0.3 11.5 0.2 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.7 KXL50485.1 - 0.13 11.2 0.4 0.35 9.7 0.1 1.8 2 0 0 2 2 2 0 AAA-like domain AAA_30 PF13604.6 KXL50485.1 - 0.19 11.4 0.3 0.91 9.2 0.3 1.9 1 1 0 1 1 1 0 AAA domain MTABC_N PF16185.5 KXL50485.1 - 6.9 6.1 11.8 0.44 10.0 0.1 3.0 4 0 0 4 4 4 0 Mitochondrial ABC-transporter N-terminal five TM region GalKase_gal_bdg PF10509.9 KXL50487.1 - 1e-20 73.0 0.0 2e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 KXL50487.1 - 5.6e-16 58.5 1.7 1.3e-15 57.3 1.7 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KXL50487.1 - 3.2e-15 56.3 0.0 8.1e-15 55.0 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal MttA_Hcf106 PF02416.16 KXL50487.1 - 0.0066 15.8 0.1 0.028 13.8 0.1 2.1 1 0 0 1 1 1 1 mttA/Hcf106 family LRR_4 PF12799.7 KXL50488.1 - 1.3e-19 69.9 20.3 1.1e-05 25.6 0.1 6.8 3 2 3 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXL50488.1 - 1.3e-16 60.1 16.4 7.8e-05 22.4 0.3 5.7 4 1 2 6 6 6 6 Leucine rich repeat LRR_6 PF13516.6 KXL50488.1 - 9.9e-09 34.6 12.5 1.8 8.8 0.0 9.4 9 1 1 10 10 10 3 Leucine Rich repeat LRR_1 PF00560.33 KXL50488.1 - 4.1e-07 29.7 17.4 2 9.3 0.1 9.0 9 2 1 10 10 10 3 Leucine Rich Repeat LRR_9 PF14580.6 KXL50488.1 - 0.00042 19.9 3.6 0.01 15.3 0.8 3.0 2 2 1 3 3 3 1 Leucine-rich repeat Asp PF00026.23 KXL50490.1 - 1.8e-05 24.3 0.0 3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease KRE9 PF05390.11 KXL50490.1 - 0.47 11.2 2.8 3.8 8.3 0.1 3.0 4 0 0 4 4 4 0 Yeast cell wall synthesis protein KRE9/KNH1 AMP-binding PF00501.28 KXL50492.1 - 1.1e-93 314.2 0.0 1.3e-93 313.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXL50492.1 - 1.4e-12 48.4 0.1 3e-12 47.3 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.18 KXL50494.1 - 2.1e-13 49.9 5.0 3.9e-12 45.8 5.1 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KXL50494.1 - 2.6e-08 33.9 6.8 0.0025 18.2 1.1 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.18 KXL50494.1 - 5.3e-05 23.3 9.9 5.3e-05 23.3 9.9 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 KXL50494.1 - 9.2e-05 22.7 7.8 0.029 14.8 1.3 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXL50494.1 - 0.00038 21.0 13.4 0.038 14.8 1.0 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXL50494.1 - 0.012 15.9 0.5 3.6 8.0 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Sprouty PF05210.13 KXL50494.1 - 0.12 12.8 8.5 18 5.8 6.3 3.1 2 1 0 2 2 2 0 Sprouty protein (Spry) zf-C2H2_6 PF13912.6 KXL50494.1 - 1 9.5 5.6 2.6 8.1 0.5 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Glyco_hydro_127 PF07944.12 KXL50495.1 - 1.1e-122 410.2 0.0 1.4e-122 409.9 0.0 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Sugar_tr PF00083.24 KXL50496.1 - 9e-64 216.0 6.3 1e-63 215.8 6.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL50496.1 - 1.7e-16 60.1 9.1 1.7e-16 60.1 9.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily KbaA PF14089.6 KXL50496.1 - 0.02 14.8 2.2 0.043 13.7 2.2 1.5 1 0 0 1 1 1 0 KinB-signalling pathway activation in sporulation MFS_1_like PF12832.7 KXL50496.1 - 9.7 4.9 10.7 0.66 8.8 1.9 2.6 3 0 0 3 3 3 0 MFS_1 like family Myb_DNA-binding PF00249.31 KXL50497.1 - 4.2e-14 52.4 2.8 0.00095 19.3 0.0 3.6 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXL50497.1 - 1.1e-13 51.2 3.1 0.0024 18.1 0.0 4.3 4 0 0 4 4 4 4 Myb-like DNA-binding domain HTH_38 PF13936.6 KXL50497.1 - 3.3e-05 23.5 1.1 0.2 11.4 0.0 3.5 4 0 0 4 4 4 2 Helix-turn-helix domain Rap1_C PF11626.8 KXL50497.1 - 0.025 14.7 0.3 2.3 8.4 0.1 2.9 1 1 2 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain WD40 PF00400.32 KXL50498.1 - 4.1e-10 40.1 8.0 0.053 14.4 0.1 5.6 6 1 1 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL50498.1 - 0.00088 19.5 0.0 2.9 8.3 0.0 3.7 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 KXL50498.1 - 0.011 15.1 0.0 0.05 12.9 0.0 1.9 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 KXL50498.1 - 0.022 13.1 0.2 0.053 11.8 0.1 1.7 1 1 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Nucleoporin_N PF08801.11 KXL50498.1 - 0.022 13.5 1.0 0.76 8.4 0.2 2.8 2 1 1 3 3 3 0 Nup133 N terminal like CMS1 PF14617.6 KXL50499.1 - 6.4e-80 268.1 2.1 7.6e-80 267.9 2.1 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 KXL50499.1 - 0.00083 19.2 0.0 0.001 18.9 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase MFS_1 PF07690.16 KXL50500.1 - 3.5e-34 118.3 33.7 9.1e-24 84.0 11.6 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL50500.1 - 1e-10 41.1 22.6 6.4e-10 38.5 11.9 3.3 3 1 0 3 3 3 2 Sugar (and other) transporter SID-1_RNA_chan PF13965.6 KXL50500.1 - 0.007 14.8 0.3 0.013 14.0 0.3 1.4 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 tRNA-synt_2 PF00152.20 KXL50501.1 - 5.6e-74 249.0 0.0 7.7e-74 248.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KXL50501.1 - 0.00013 21.9 0.0 0.00027 20.9 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KXL50501.1 - 0.00024 20.7 0.2 0.45 9.9 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Hydrolase_6 PF13344.6 KXL50502.1 - 1.3e-23 83.0 0.0 3.7e-23 81.5 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXL50502.1 - 3.6e-20 71.8 0.0 1.4e-19 69.9 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KXL50502.1 - 8.9e-05 22.9 0.0 0.13 12.5 0.0 2.9 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXL50502.1 - 0.03 14.4 0.0 9.6 6.3 0.0 2.7 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase Semialdhyde_dhC PF02774.18 KXL50503.1 - 1.8e-38 132.5 0.0 2.6e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KXL50503.1 - 7.5e-26 90.9 0.0 8e-18 65.0 0.0 2.6 2 1 1 3 3 3 2 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KXL50503.1 - 0.0095 16.2 0.0 0.051 13.8 0.0 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Gp_dh_C PF02800.20 KXL50503.1 - 0.011 15.3 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Peptidase_S10 PF00450.22 KXL50504.1 - 8.4e-77 259.3 0.1 1.1e-76 259.0 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Glyco_hydro_30C PF17189.4 KXL50505.1 - 7e-09 35.8 1.1 5.7e-08 32.9 0.1 2.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydr_30_2 PF14587.6 KXL50505.1 - 1e-08 35.2 0.2 3e-08 33.6 0.0 1.8 2 1 0 2 2 2 1 O-Glycosyl hydrolase family 30 Glyco_hydro_30 PF02055.16 KXL50505.1 - 7.3e-07 28.5 0.0 1.1e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 KXL50505.1 - 0.0045 16.3 0.1 0.0082 15.4 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 PMSR PF01625.21 KXL50505.1 - 0.032 14.4 0.0 0.079 13.1 0.0 1.6 1 0 0 1 1 1 0 Peptide methionine sulfoxide reductase BACON PF13004.7 KXL50505.1 - 0.064 13.2 3.0 0.21 11.6 3.0 1.9 1 0 0 1 1 1 0 Putative binding domain, N-terminal GPI2 PF06432.11 KXL50506.1 - 4.7e-127 423.2 0.5 5.7e-127 422.9 0.5 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Intg_mem_TP0381 PF09529.10 KXL50506.1 - 4.2 6.8 9.1 4.5 6.7 0.1 2.5 2 1 0 2 2 2 0 Integral membrane protein (intg_mem_TP0381) WD40 PF00400.32 KXL50507.1 - 5e-22 77.8 22.0 0.0012 19.6 0.1 7.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 KXL50507.1 - 0.0013 17.3 1.2 0.059 11.9 0.1 3.2 4 0 0 4 4 4 1 Cytochrome D1 heme domain ANAPC4_WD40 PF12894.7 KXL50507.1 - 0.022 15.1 0.0 1.1 9.6 0.0 3.7 3 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KXL50507.1 - 0.03 14.8 0.2 1.2 9.8 0.0 3.5 4 0 0 4 4 4 0 PQQ-like domain Glyoxal_oxid_N PF07250.11 KXL50507.1 - 0.14 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus Ribosomal_60s PF00428.19 KXL50507.1 - 0.52 10.9 3.4 0.18 12.4 0.3 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein SecE PF00584.20 KXL50508.1 - 1.3e-15 57.0 0.0 1.5e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex FSH1 PF03959.13 KXL50509.1 - 2.1e-60 204.0 0.0 2.7e-60 203.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 KXL50509.1 - 0.00096 18.7 0.0 0.0024 17.4 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KXL50509.1 - 0.02 15.5 0.4 0.032 14.8 0.4 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXL50509.1 - 0.14 11.4 0.0 0.58 9.4 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 COesterase PF00135.28 KXL50510.1 - 3.1e-95 320.0 0.9 1.1e-94 318.1 0.9 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXL50510.1 - 0.0027 17.6 0.0 0.0053 16.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold FTZ PF03867.14 KXL50510.1 - 1.7 8.1 6.3 0.4 10.2 0.2 2.2 2 0 0 2 2 2 0 Fushi tarazu (FTZ), N-terminal region Glyco_hydro_39 PF01229.17 KXL50511.1 - 0.00094 17.9 0.2 0.0013 17.4 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 ssDNA-exonuc_C PF10141.9 KXL50512.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Single-strand DNA-specific exonuclease, C terminal domain KH_6 PF15985.5 KXL50513.1 - 7.4e-17 61.4 0.2 1.6e-16 60.4 0.2 1.6 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 KXL50513.1 - 3.5e-16 58.9 0.8 8.9e-16 57.6 0.5 1.8 2 0 0 2 2 2 1 Exosome complex exonuclease Rrp40 N-terminal domain Sugar_tr PF00083.24 KXL50514.1 - 7.2e-85 285.5 18.8 8.3e-85 285.3 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL50514.1 - 4e-18 65.5 24.1 6.1e-18 64.9 20.0 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 KXL50514.1 - 3.2e-06 26.0 13.8 6.8e-05 21.6 0.6 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 KXL50514.1 - 0.0034 16.3 4.4 0.0034 16.3 4.4 2.3 2 1 0 2 2 2 1 MFS_1 like family OppC_N PF12911.7 KXL50514.1 - 0.17 11.9 0.1 0.17 11.9 0.1 2.8 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C HSP70 PF00012.20 KXL50515.1 - 1.8e-72 244.4 1.2 2.4e-72 244.0 1.2 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXL50515.1 - 1.5e-07 30.6 0.1 2.9e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.8 KXL50515.1 - 0.0012 18.0 0.1 0.18 10.8 0.0 2.8 2 1 0 3 3 3 2 Type IV pilus assembly protein PilM; Rrp40_N PF18311.1 KXL50516.1 - 6.1e-14 51.7 1.3 7.6e-14 51.4 1.3 1.1 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain Melibiase_2 PF16499.5 KXL50518.1 - 1.1e-59 202.0 4.0 2.8e-58 197.4 4.0 2.2 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KXL50518.1 - 6.1e-12 45.5 0.0 3.7e-09 36.5 0.0 2.6 2 0 0 2 2 2 2 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KXL50518.1 - 5.1e-07 29.0 0.0 8.1e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 Melibiase Sugar_tr PF00083.24 KXL50519.1 - 6e-76 256.1 26.6 6.9e-76 255.9 26.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL50519.1 - 3.6e-11 42.6 28.5 3.6e-11 42.6 28.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Alpha-amylase PF00128.24 KXL50520.1 - 1.3e-98 330.7 0.1 1.9e-98 330.1 0.1 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KXL50520.1 - 0.00046 20.2 0.0 0.0014 18.7 0.0 1.8 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain Glyco_hydro_114 PF03537.13 KXL50520.1 - 0.031 13.6 0.0 0.25 10.6 0.0 2.1 2 0 0 2 2 2 0 Glycoside-hydrolase family GH114 DHHC PF01529.20 KXL50521.1 - 1.2e-06 28.7 5.6 1.2e-06 28.7 5.6 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase CReP_N PF10472.9 KXL50523.1 - 0.0045 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 eIF2-alpha phosphatase phosphorylation constitutive repressor SET PF00856.28 KXL50524.1 - 3e-16 60.3 0.3 2.1e-15 57.5 0.3 1.9 1 1 0 1 1 1 1 SET domain Methyltransf_16 PF10294.9 KXL50525.1 - 1.6e-10 41.0 0.0 3.9e-10 39.7 0.0 1.5 1 1 0 1 1 1 1 Lysine methyltransferase LCM PF04072.14 KXL50525.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 1 0 1 1 1 0 Leucine carboxyl methyltransferase Pribosyltran PF00156.27 KXL50526.1 - 8.4e-13 48.1 0.0 1.3e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GAF_2 PF13185.6 KXL50526.1 - 0.14 12.4 0.1 4.6 7.5 0.0 2.2 1 1 1 2 2 2 0 GAF domain AMP-binding PF00501.28 KXL50527.1 - 8.4e-92 307.9 0.0 1.3e-91 307.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXL50527.1 - 6.1e-06 27.1 0.2 1.7e-05 25.7 0.2 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FAD_binding_3 PF01494.19 KXL50528.1 - 1.7e-15 57.2 0.2 1.2e-06 28.0 0.0 2.9 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXL50528.1 - 1.8e-05 24.9 0.2 4.4e-05 23.6 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXL50528.1 - 0.0006 19.5 0.0 0.0009 18.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXL50528.1 - 0.0043 16.3 0.1 0.0075 15.5 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXL50528.1 - 0.02 15.4 0.0 0.042 14.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KXL50528.1 - 0.038 13.6 0.1 0.065 12.9 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.24 KXL50528.1 - 0.039 13.0 0.1 0.057 12.5 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain SE PF08491.10 KXL50528.1 - 0.04 13.0 0.0 0.092 11.8 0.0 1.5 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_3 PF13738.6 KXL50528.1 - 0.084 12.1 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 KXL50529.1 - 5.4e-70 235.8 0.0 6.2e-70 235.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL50529.1 - 3.5e-43 147.8 0.0 4.2e-43 147.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXL50529.1 - 4e-09 36.2 0.0 1.8e-07 30.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KXL50529.1 - 0.00015 21.2 0.6 0.00023 20.6 0.6 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXL50529.1 - 0.0038 16.2 0.0 0.0049 15.8 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KXL50529.1 - 0.035 14.0 0.4 0.051 13.5 0.4 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KXL50529.1 - 0.036 13.6 0.0 0.076 12.5 0.0 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 KXL50529.1 - 0.12 12.0 0.1 0.51 9.9 0.0 1.8 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Xan_ur_permease PF00860.20 KXL50530.1 - 2.9e-65 220.5 33.6 1e-63 215.4 33.6 2.1 1 1 0 1 1 1 1 Permease family UCR_Fe-S_N PF10399.9 KXL50530.1 - 6.6 6.2 5.7 26 4.3 0.6 2.9 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Dak1 PF02733.17 KXL50531.1 - 7.3e-90 301.0 0.0 8.3e-90 300.8 0.0 1.0 1 0 0 1 1 1 1 Dak1 domain rhaM PF05336.13 KXL50532.1 - 5.4e-37 126.2 0.5 6e-37 126.0 0.5 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase DUF3575 PF12099.8 KXL50532.1 - 0.036 13.4 0.1 0.044 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3575) F-box-like PF12937.7 KXL50533.1 - 3.6e-06 26.8 0.3 7.7e-06 25.7 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXL50533.1 - 0.037 13.9 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 F-box domain ECM11 PF15463.6 KXL50534.1 - 1.5e-33 116.2 0.5 1.5e-33 116.2 0.5 2.5 4 0 0 4 4 4 1 Extracellular mutant protein 11 RCR PF12273.8 KXL50535.1 - 2 9.1 5.7 5.2 7.7 5.7 1.8 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red zf-H2C2_2 PF13465.6 KXL50537.1 - 2.5e-09 37.1 17.7 4.9e-05 23.6 3.3 4.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KXL50537.1 - 1.8e-08 34.4 14.0 0.00038 20.8 4.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXL50537.1 - 7.3e-05 23.3 11.3 0.043 14.7 3.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXL50537.1 - 0.012 15.8 0.4 0.045 14.1 0.4 2.0 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KXL50537.1 - 0.027 14.5 1.2 2 8.5 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 KXL50537.1 - 0.17 12.5 0.1 0.17 12.5 0.1 2.7 2 1 1 3 3 3 0 FOXP coiled-coil domain TFIIA PF03153.13 KXL50537.1 - 1.8 8.5 18.7 2.5 8.0 18.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-H2C2_5 PF13909.6 KXL50537.1 - 5 7.0 14.2 2.9 7.7 0.2 3.6 3 0 0 3 3 3 0 C2H2-type zinc-finger domain RhoGAP PF00620.27 KXL50538.1 - 7.6e-43 146.0 0.1 1.4e-42 145.1 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 KXL50538.1 - 5.4e-15 55.8 0.0 8.9e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 PH domain NRBF2 PF08961.10 KXL50538.1 - 0.051 13.2 0.7 0.14 11.7 0.7 1.8 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator PH_8 PF15409.6 KXL50538.1 - 0.051 13.8 0.0 0.31 11.3 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain NTP_transf_9 PF04248.12 KXL50539.1 - 3.6e-39 132.5 0.0 3.4e-32 110.2 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF427) SBP56 PF05694.11 KXL50539.1 - 0.0049 15.8 0.0 0.0066 15.3 0.0 1.1 1 0 0 1 1 1 1 56kDa selenium binding protein (SBP56) Pro_racemase PF05544.11 KXL50540.1 - 1.6e-65 221.3 0.0 2.2e-65 220.8 0.0 1.1 1 0 0 1 1 1 1 Proline racemase LSM PF01423.22 KXL50541.1 - 2.2e-19 68.9 0.1 2.5e-19 68.7 0.1 1.0 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.7 KXL50541.1 - 0.025 14.7 0.0 0.03 14.4 0.0 1.3 1 1 0 1 1 1 0 Scd6-like Sm domain SM-ATX PF14438.6 KXL50541.1 - 0.046 13.9 0.0 0.054 13.6 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain NAD_binding_10 PF13460.6 KXL50542.1 - 2.7e-12 47.0 0.0 4.1e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXL50542.1 - 2.5e-05 24.0 0.1 4.3e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KXL50542.1 - 0.047 13.1 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF3602 PF12223.8 KXL50543.1 - 1.1e-13 51.5 12.3 2.8e-12 47.1 1.4 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) DUF1534 PF07551.11 KXL50543.1 - 1.4 8.7 4.7 5.6 6.8 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1534) DUF1640 PF07798.11 KXL50544.1 - 2.1e-56 190.7 11.1 2.4e-56 190.5 11.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) LMBR1 PF04791.16 KXL50544.1 - 0.00061 18.8 2.0 0.00065 18.7 2.0 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein XhlA PF10779.9 KXL50544.1 - 0.087 13.0 0.7 0.087 13.0 0.7 2.5 3 0 0 3 3 3 0 Haemolysin XhlA Exonuc_VII_L PF02601.15 KXL50544.1 - 2.7 7.5 8.9 3.6 7.1 8.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit SBF PF01758.16 KXL50545.1 - 1.5e-49 168.4 14.0 3.4e-49 167.2 14.0 1.6 1 0 0 1 1 1 1 Sodium Bile acid symporter family Rhodanese PF00581.20 KXL50546.1 - 0.0035 17.9 0.0 0.0049 17.4 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain MFS_1 PF07690.16 KXL50548.1 - 1.4e-42 145.9 48.7 1.4e-42 145.9 48.7 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXL50548.1 - 1.3e-10 40.4 23.7 1.9e-10 39.8 23.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXL50548.1 - 1.1e-06 27.9 13.2 1.1e-06 27.9 13.2 3.9 2 2 1 3 3 3 2 Sugar (and other) transporter V-ATPase_G_2 PF16999.5 KXL50548.1 - 0.31 11.5 2.2 0.51 10.8 2.2 1.2 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit 14-3-3 PF00244.20 KXL50549.1 - 2.1e-101 338.1 0.7 2.5e-101 337.8 0.7 1.1 1 0 0 1 1 1 1 14-3-3 protein ARL2_Bind_BART PF11527.8 KXL50549.1 - 0.082 13.0 0.3 4.2 7.5 0.2 2.3 1 1 1 2 2 2 0 The ARF-like 2 binding protein BART NUFIP1 PF10453.9 KXL50550.1 - 0.009 15.8 1.3 0.017 15.0 1.3 1.4 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Zn_clus PF00172.18 KXL50551.1 - 1.5e-07 31.4 7.4 3.5e-07 30.2 7.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_3 PF00202.21 KXL50552.1 - 1.2e-122 409.5 0.0 1.5e-122 409.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KXL50552.1 - 0.0042 16.3 0.0 0.0081 15.4 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KXL50552.1 - 0.0056 16.0 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase OAM_dimer PF16554.5 KXL50552.1 - 0.064 13.7 0.1 0.17 12.3 0.1 1.7 1 0 0 1 1 1 0 Dimerisation domain of d-ornithine 4,5-aminomutase zf-C3HC4_3 PF13920.6 KXL50553.1 - 5.3e-08 32.6 6.8 5.3e-08 32.6 6.8 2.6 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXL50553.1 - 5.6e-08 32.5 8.4 5.6e-08 32.5 8.4 2.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXL50553.1 - 6.8e-08 32.2 8.8 6.8e-08 32.2 8.8 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXL50553.1 - 1.4e-07 31.5 9.3 1.4e-07 31.5 9.3 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KXL50553.1 - 2.7e-07 30.8 8.5 2.7e-07 30.8 8.5 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KXL50553.1 - 1.8e-06 27.9 6.4 1.8e-06 27.9 6.4 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXL50553.1 - 5.6e-06 26.2 8.8 5.6e-06 26.2 8.8 3.1 3 1 1 4 4 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KXL50553.1 - 1.6e-05 24.7 13.9 3.6e-05 23.5 3.5 3.1 2 1 1 3 3 3 2 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KXL50553.1 - 0.0039 17.5 7.6 0.0039 17.5 7.6 2.8 3 1 0 3 3 2 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 KXL50553.1 - 0.0061 16.4 2.8 0.0061 16.4 2.8 2.3 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KXL50553.1 - 0.07 13.3 4.2 0.18 12.0 4.2 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 U-box PF04564.15 KXL50553.1 - 0.086 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 U-box domain zf-Nse PF11789.8 KXL50553.1 - 0.2 11.5 4.2 0.15 11.9 2.1 1.8 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit DUF1272 PF06906.11 KXL50553.1 - 0.3 11.2 12.1 0.11 12.6 4.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-ribbon_3 PF13248.6 KXL50553.1 - 1.6 8.2 7.4 2.9 7.4 0.4 3.6 3 0 0 3 3 3 0 zinc-ribbon domain zf-RING_4 PF14570.6 KXL50553.1 - 3.2 7.6 14.4 0.037 13.8 3.9 2.8 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KXL50553.1 - 3.4 7.8 12.3 0.099 12.7 1.1 2.8 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.7 KXL50553.1 - 6.5 6.9 15.9 11 6.1 1.5 2.8 1 1 1 2 2 2 0 Double zinc ribbon 4PPT_N PF17837.1 KXL50554.1 - 0.13 12.4 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain 2OG-Fe_Oxy_2 PF10014.9 KXL50554.1 - 0.15 11.8 0.1 0.29 10.9 0.1 1.4 1 0 0 1 1 1 0 2OG-Fe dioxygenase Tup_N PF08581.10 KXL50555.1 - 0.029 14.7 0.1 0.049 13.9 0.1 1.3 1 0 0 1 1 1 0 Tup N-terminal DUF2383 PF09537.10 KXL50555.1 - 0.2 12.0 0.1 0.38 11.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) zf-H2C2_2 PF13465.6 KXL50556.1 - 1.8e-14 53.4 13.8 4e-09 36.5 2.2 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KXL50556.1 - 6.1e-11 42.1 21.3 0.0025 18.2 4.8 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXL50556.1 - 7.6e-08 32.6 18.1 0.044 14.6 2.3 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXL50556.1 - 6.9e-06 25.9 13.1 0.0018 18.2 0.0 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf_UBZ PF18439.1 KXL50556.1 - 0.0037 16.8 1.0 0.96 9.1 0.0 2.5 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KXL50556.1 - 0.0052 16.9 5.1 0.014 15.5 3.8 2.2 1 1 1 2 2 2 2 Zinc ribbon domain zf-C2HE PF16278.5 KXL50556.1 - 0.0062 17.0 14.4 0.012 16.0 1.0 3.0 1 1 2 3 3 3 2 C2HE / C2H2 / C2HC zinc-binding finger XPA_N PF01286.18 KXL50556.1 - 0.0097 15.9 0.7 1.4 9.0 0.1 2.4 2 0 0 2 2 2 1 XPA protein N-terminal OSTMP1 PF09777.9 KXL50556.1 - 0.011 15.1 0.2 0.013 14.9 0.2 1.1 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor DZR PF12773.7 KXL50556.1 - 0.015 15.3 4.6 0.032 14.2 4.6 1.7 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 KXL50556.1 - 0.017 15.1 0.6 0.021 14.9 0.6 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-FPG_IleRS PF06827.14 KXL50556.1 - 0.022 14.6 5.7 0.073 12.9 0.4 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-C2H2_8 PF15909.5 KXL50556.1 - 0.022 15.0 5.0 0.038 14.3 5.0 1.5 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-C2HC_2 PF13913.6 KXL50556.1 - 0.032 14.1 0.8 0.032 14.1 0.8 2.3 3 1 0 3 3 1 0 zinc-finger of a C2HC-type zinc_ribbon_15 PF17032.5 KXL50556.1 - 0.033 14.9 0.9 0.047 14.5 0.9 1.4 1 0 0 1 1 1 0 zinc-ribbon family zf-C2H2_jaz PF12171.8 KXL50556.1 - 0.044 14.1 5.9 1.6 9.1 0.2 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding TFIIS_C PF01096.18 KXL50556.1 - 0.058 13.3 3.2 2.5 8.0 0.3 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-C2H2_9 PF16293.5 KXL50556.1 - 0.099 12.5 1.1 13 5.7 0.0 2.7 1 1 2 3 3 3 0 C2H2 type zinc-finger (1 copy) zinc-ribbons_6 PF07191.12 KXL50556.1 - 0.11 12.5 3.9 3.8 7.6 4.1 2.3 1 1 0 1 1 1 0 zinc-ribbons zf-C2H2_11 PF16622.5 KXL50556.1 - 0.23 11.3 0.1 0.23 11.3 0.1 3.1 3 1 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 KXL50556.1 - 0.31 11.7 7.1 0.46 11.2 2.5 2.5 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-CHCC PF10276.9 KXL50556.1 - 0.43 10.7 5.6 2 8.5 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger domain FYDLN_acid PF09538.10 KXL50556.1 - 0.55 10.9 3.3 5.3 7.8 2.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) GAGA PF09237.11 KXL50556.1 - 0.65 9.9 8.9 0.33 10.8 3.9 2.5 1 1 1 2 2 2 0 GAGA factor Rubredoxin_2 PF18073.1 KXL50556.1 - 0.72 9.6 5.4 6.2 6.6 0.8 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain C1_4 PF07975.12 KXL50556.1 - 1.1 9.5 6.5 2.1 8.6 4.0 1.9 1 1 0 1 1 1 0 TFIIH C1-like domain zf-HIT PF04438.16 KXL50556.1 - 1.4 8.9 6.8 7.8 6.5 0.2 2.9 3 0 0 3 3 3 0 HIT zinc finger zf_C2H2_ZHX PF18387.1 KXL50556.1 - 1.6 8.4 9.7 0.76 9.5 0.9 2.9 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf_ZIC PF18366.1 KXL50556.1 - 1.9 8.6 9.6 2 8.6 0.5 2.9 1 1 2 3 3 3 0 Zic proteins zinc finger domain FYVE PF01363.21 KXL50556.1 - 2.6 8.2 10.6 0.47 10.6 6.2 2.0 1 1 1 2 2 2 0 FYVE zinc finger zf-met PF12874.7 KXL50556.1 - 3 8.4 10.0 4 8.0 0.5 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type COesterase PF00135.28 KXL50558.1 - 8.9e-64 216.2 0.0 2.5e-63 214.7 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXL50558.1 - 8.2e-06 25.8 0.0 2.9e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DNA_pol_A_exo1 PF01612.20 KXL50559.1 - 2.5e-15 56.7 0.2 3.9e-15 56.0 0.2 1.3 1 0 0 1 1 1 1 3'-5' exonuclease HTH_40 PF14493.6 KXL50559.1 - 0.0064 16.9 0.1 0.043 14.3 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain 3-alpha PF03475.14 KXL50559.1 - 0.025 14.4 0.0 0.06 13.2 0.0 1.6 1 0 0 1 1 1 0 3-alpha domain VWA PF00092.28 KXL50560.1 - 0.012 15.8 0.0 0.035 14.4 0.0 1.8 1 1 0 1 1 1 0 von Willebrand factor type A domain VWA_2 PF13519.6 KXL50560.1 - 0.033 14.8 0.0 0.11 13.2 0.0 1.9 1 0 0 1 1 1 0 von Willebrand factor type A domain Totivirus_coat PF05518.11 KXL50560.1 - 0.64 8.0 3.7 1 7.4 3.7 1.2 1 0 0 1 1 1 0 Totivirus coat protein HMGL-like PF00682.19 KXL50561.1 - 1.6e-80 270.5 1.2 2.4e-80 269.9 1.2 1.3 1 0 0 1 1 1 1 HMGL-like Trp_syntA PF00290.20 KXL50561.1 - 0.029 13.2 0.0 4.6 6.0 0.0 2.3 2 0 0 2 2 2 0 Tryptophan synthase alpha chain Peptidase_C47 PF05543.13 KXL50561.1 - 0.14 11.7 0.0 0.46 10.0 0.0 1.9 1 0 0 1 1 1 0 Staphopain peptidase C47 Abhydrolase_3 PF07859.13 KXL50562.1 - 2.9e-12 46.9 0.0 2.5e-11 43.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXL50562.1 - 5.1e-07 30.5 0.5 6.8e-07 30.1 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXL50562.1 - 9.9e-07 28.4 0.0 0.016 14.7 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 KXL50562.1 - 0.00033 20.3 0.0 0.0011 18.6 0.0 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 KXL50562.1 - 0.001 18.0 0.0 0.0021 17.0 0.0 1.4 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KXL50562.1 - 0.0025 16.9 0.0 0.0034 16.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase AXE1 PF05448.12 KXL50562.1 - 0.012 14.3 0.0 0.016 13.9 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF1161 PF06649.12 KXL50562.1 - 0.02 15.1 0.0 0.039 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1161) Hydrolase_4 PF12146.8 KXL50562.1 - 0.061 12.6 0.0 0.12 11.6 0.0 1.6 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Esterase PF00756.20 KXL50562.1 - 0.092 12.4 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Frag1 PF10277.9 KXL50563.1 - 2.2e-43 148.3 17.2 2.6e-43 148.1 17.2 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family SUR7 PF06687.12 KXL50563.1 - 0.038 13.6 6.6 0.31 10.7 0.3 2.4 1 1 1 2 2 2 0 SUR7/PalI family CbtB PF09489.10 KXL50563.1 - 0.47 10.6 3.1 0.37 10.9 0.3 2.3 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) Glyco_hydro_47 PF01532.20 KXL50564.1 - 2.4e-165 550.9 0.0 3.1e-165 550.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Ish1 PF10281.9 KXL50565.1 - 9e-07 29.1 0.0 1.3e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein UbiA PF01040.18 KXL50565.1 - 0.012 15.0 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 0 UbiA prenyltransferase family Ribosomal_L38e PF01781.18 KXL50567.1 - 5.4e-34 116.1 0.9 6.8e-34 115.8 0.9 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family MFS_1 PF07690.16 KXL50568.1 - 2.2e-14 53.1 47.6 1.9e-09 37.0 26.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_76 PF03663.14 KXL50569.1 - 2.2e-44 152.5 9.3 3.3e-44 151.9 9.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KXL50569.1 - 1.9e-06 27.2 0.6 0.0019 17.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 KXL50569.1 - 0.0047 16.4 0.4 0.16 11.5 0.1 2.4 1 1 0 2 2 2 1 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_127 PF07944.12 KXL50569.1 - 0.015 13.8 0.0 0.28 9.6 0.0 2.2 1 1 1 2 2 2 0 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_47 PF01532.20 KXL50569.1 - 0.025 13.5 0.1 0.58 9.0 0.1 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 47 FMO-like PF00743.19 KXL50570.1 - 4.8e-14 51.7 0.1 4.3e-13 48.5 0.1 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXL50570.1 - 4.9e-12 45.7 0.0 2.3e-11 43.5 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXL50570.1 - 2.4e-08 33.6 0.0 1.6e-07 30.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXL50570.1 - 9.9e-08 31.5 0.0 3.6e-06 26.4 0.0 2.4 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KXL50570.1 - 3e-07 30.6 0.0 1.6e-05 25.0 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXL50570.1 - 6.6e-07 28.8 0.0 0.00019 20.7 0.0 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KXL50570.1 - 4.6e-05 23.2 0.2 0.0058 16.3 0.0 3.4 3 1 1 4 4 4 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXL50570.1 - 6.1e-05 23.5 0.0 0.051 14.1 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 KXL50570.1 - 0.0027 16.3 0.0 0.15 10.6 0.0 2.5 2 1 1 3 3 3 1 Malate:quinone oxidoreductase (Mqo) Lycopene_cycl PF05834.12 KXL50570.1 - 0.0032 16.6 0.0 0.051 12.6 0.0 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_7 PF13241.6 KXL50570.1 - 0.087 13.3 0.0 0.23 11.9 0.0 1.6 2 0 0 2 2 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 KXL50570.1 - 0.11 12.6 0.0 0.65 10.1 0.0 2.2 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase SIS PF01380.22 KXL50571.1 - 8.5e-58 193.9 0.0 1.2e-30 106.0 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KXL50571.1 - 6.2e-18 65.3 0.0 1.2e-17 64.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KXL50571.1 - 2.2e-11 43.7 0.0 5.5e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KXL50571.1 - 0.0033 16.4 0.0 0.0063 15.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 KXL50571.1 - 0.061 13.4 0.1 1 9.4 0.0 2.7 3 0 0 3 3 3 0 SIS domain GST_N_2 PF13409.6 KXL50573.1 - 1e-07 32.1 0.1 2.7e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXL50573.1 - 9.2e-07 29.0 0.0 1.7e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXL50573.1 - 4.7e-06 26.7 0.0 1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXL50573.1 - 1.9e-05 24.9 0.0 4e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXL50573.1 - 0.00014 22.2 0.0 0.00026 21.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXL50573.1 - 0.00081 19.4 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.16 KXL50574.1 - 5e-08 32.3 16.5 6.7e-08 31.8 16.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily PTR2 PF00854.21 KXL50574.1 - 0.022 13.6 0.2 0.037 12.9 0.2 1.4 1 0 0 1 1 1 0 POT family DUF805 PF05656.14 KXL50574.1 - 0.1 13.0 2.1 0.19 12.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF805) HlyIII PF03006.20 KXL50576.1 - 1.3e-59 201.7 17.5 1.6e-59 201.4 17.5 1.1 1 0 0 1 1 1 1 Haemolysin-III related adh_short PF00106.25 KXL50577.1 - 3e-18 66.0 0.0 1.1e-15 57.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXL50577.1 - 3e-14 53.1 0.0 3e-11 43.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL50577.1 - 2.6e-05 24.2 0.1 5.2e-05 23.2 0.0 1.5 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 KXL50577.1 - 0.075 12.9 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H-binding PhyH PF05721.13 KXL50578.1 - 7.6e-25 88.4 0.0 1.1e-24 87.9 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Cupin_2 PF07883.11 KXL50578.1 - 0.088 12.5 0.4 0.38 10.5 0.0 2.0 2 0 0 2 2 2 0 Cupin domain AMP-binding PF00501.28 KXL50579.1 - 1.2e-71 241.6 0.0 1.4e-71 241.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXL50579.1 - 1e-05 26.4 0.0 3.1e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AAA PF00004.29 KXL50581.1 - 2.7e-42 144.3 0.0 4.6e-42 143.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KXL50581.1 - 3e-11 43.1 0.1 9.4e-11 41.5 0.0 1.9 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KXL50581.1 - 1.3e-10 40.9 0.1 3e-10 39.7 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KXL50581.1 - 7.5e-07 29.7 0.1 0.00042 20.7 0.1 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KXL50581.1 - 3.5e-06 27.1 0.1 8.2e-05 22.6 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KXL50581.1 - 8.1e-06 26.1 0.0 2.5e-05 24.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KXL50581.1 - 1.1e-05 25.3 0.0 2.4e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXL50581.1 - 0.00033 20.9 0.1 0.0063 16.8 0.1 2.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KXL50581.1 - 0.00075 18.7 0.0 0.0017 17.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 KXL50581.1 - 0.002 17.7 0.0 0.004 16.7 0.0 1.5 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 KXL50581.1 - 0.002 18.6 0.0 0.0081 16.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 KXL50581.1 - 0.0026 17.7 0.0 0.0057 16.6 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Prot_ATP_OB_N PF17758.1 KXL50581.1 - 0.0043 16.7 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain TIP49 PF06068.13 KXL50581.1 - 0.0051 16.1 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 KXL50581.1 - 0.0056 16.1 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KXL50581.1 - 0.01 16.0 0.0 0.027 14.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KXL50581.1 - 0.011 15.5 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KXL50581.1 - 0.012 16.0 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 KXL50581.1 - 0.015 15.0 0.0 0.051 13.3 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 KXL50581.1 - 0.018 15.1 0.0 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KXL50581.1 - 0.025 13.9 0.1 0.095 12.0 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.6 KXL50581.1 - 0.031 14.0 0.0 0.075 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KXL50581.1 - 0.038 13.9 0.0 0.086 12.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KXL50581.1 - 0.045 13.5 0.1 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KXL50581.1 - 0.053 13.4 0.1 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Parvo_NS1 PF01057.17 KXL50581.1 - 0.1 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 KXL50581.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 KXL50581.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KXL50581.1 - 0.15 11.6 0.0 0.35 10.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KXL50581.1 - 0.16 11.7 0.1 0.49 10.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Enolase_C PF00113.22 KXL50582.1 - 4.7e-152 505.4 0.1 6.1e-152 505.0 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KXL50582.1 - 5.1e-57 191.7 1.7 9.7e-57 190.8 1.0 1.8 2 0 0 2 2 2 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KXL50582.1 - 5.2e-05 22.9 0.0 0.00012 21.8 0.0 1.6 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KXL50582.1 - 0.035 13.3 2.7 0.29 10.2 0.4 2.4 2 1 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus Cytochrome_C7 PF14522.6 KXL50584.1 - 0.0011 19.0 3.2 0.0018 18.2 3.2 1.4 1 0 0 1 1 1 1 Cytochrome c7 and related cytochrome c Cytochrom_c3_2 PF14537.6 KXL50584.1 - 0.028 14.9 1.9 0.053 14.0 1.9 1.5 1 0 0 1 1 1 0 Cytochrome c3 zf-C4H2 PF10146.9 KXL50584.1 - 0.039 14.2 0.6 0.069 13.5 0.6 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein Cation_efflux PF01545.21 KXL50586.1 - 0.0071 16.1 0.1 0.018 14.8 0.1 1.6 1 1 0 1 1 1 1 Cation efflux family DUF4271 PF14093.6 KXL50586.1 - 0.024 14.5 0.1 0.047 13.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) MARVEL PF01284.23 KXL50586.1 - 0.048 13.7 4.7 0.084 12.9 4.4 1.5 1 1 0 1 1 1 0 Membrane-associating domain DUF2157 PF09925.9 KXL50586.1 - 0.13 12.1 0.5 0.39 10.5 0.5 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) AAA_16 PF13191.6 KXL50587.1 - 8.6e-12 45.8 0.1 1.2e-09 38.7 0.1 2.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXL50587.1 - 6.8e-11 42.6 0.0 1.7e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KXL50587.1 - 8.8e-11 42.3 0.0 3.3e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.11 KXL50587.1 - 1.9e-05 24.5 0.1 0.00042 20.2 0.0 2.5 2 0 0 2 2 2 1 CDC6, C terminal winged helix domain AAA_lid_10 PF17872.1 KXL50587.1 - 3.6e-05 23.8 0.1 7.7e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 AAA lid domain AAA_19 PF13245.6 KXL50587.1 - 0.00059 20.2 0.2 0.023 15.0 0.2 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXL50587.1 - 0.00074 19.5 0.0 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KXL50587.1 - 0.00085 19.1 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KXL50587.1 - 0.0034 17.4 0.0 0.0064 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KXL50587.1 - 0.0088 15.3 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain NTPase_1 PF03266.15 KXL50587.1 - 0.01 15.8 0.0 0.22 11.4 0.0 2.3 2 0 0 2 2 2 1 NTPase ATPase_2 PF01637.18 KXL50587.1 - 0.018 15.0 0.0 0.22 11.4 0.0 2.2 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea DUF815 PF05673.13 KXL50587.1 - 0.054 12.7 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA12 PF10443.9 KXL50587.1 - 0.077 11.7 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 RNA12 protein AAA_7 PF12775.7 KXL50587.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 KXL50587.1 - 0.17 11.6 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain PIF1 PF05970.14 KXL50587.1 - 0.19 10.9 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase Methyltransf_25 PF13649.6 KXL50588.1 - 0.00022 21.9 0.0 0.00046 20.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL50588.1 - 0.00023 21.8 0.0 0.00052 20.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXL50588.1 - 0.00071 19.2 0.0 0.0016 18.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KXL50588.1 - 0.0028 17.5 0.0 0.031 14.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Cpn60_TCP1 PF00118.24 KXL50589.1 - 2e-143 478.6 11.8 2.3e-143 478.4 11.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 KXL50589.1 - 0.097 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat DUF5442 PF17514.2 KXL50589.1 - 0.12 12.5 0.1 0.3 11.3 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5442) Cm_res_leader PF08077.11 KXL50591.1 - 0.0013 18.5 0.2 79 3.9 0.0 6.2 7 0 0 7 7 7 1 Chloramphenicol resistance gene leader peptide Collagen PF01391.18 KXL50591.1 - 0.089 12.6 3.3 24 4.7 0.1 4.2 4 2 0 4 4 4 0 Collagen triple helix repeat (20 copies) Iso_dh PF00180.20 KXL50592.1 - 8.1e-85 285.0 0.0 1e-84 284.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DSBA PF01323.20 KXL50593.1 - 3.3e-20 72.7 0.0 3.8e-20 72.5 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain UCH PF00443.29 KXL50594.1 - 3.2e-25 89.1 0.0 4.6e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KXL50594.1 - 1.6e-09 38.0 0.1 2.8e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KXL50594.1 - 0.0029 17.3 0.1 0.038 13.6 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Erv26 PF04148.13 KXL50595.1 - 9e-89 296.7 0.1 1e-88 296.5 0.1 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF1970 PF09301.10 KXL50595.1 - 0.084 13.1 0.1 0.22 11.8 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1970) WBS_methylT PF12589.8 KXL50596.1 - 4.4e-15 56.2 4.0 7.5e-15 55.4 4.0 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 KXL50596.1 - 1.7e-11 44.6 0.0 4.3e-11 43.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL50596.1 - 9.6e-11 42.3 0.0 3.3e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL50596.1 - 4.7e-05 24.0 0.0 0.00019 22.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXL50596.1 - 7e-05 22.7 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KXL50596.1 - 0.0004 20.2 0.0 0.00061 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXL50596.1 - 0.0029 17.5 0.0 0.0045 16.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXL50596.1 - 0.014 14.7 0.0 0.042 13.2 0.0 1.8 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.14 KXL50596.1 - 0.046 13.3 0.6 2.8 7.5 0.1 2.3 1 1 1 2 2 2 0 Methyltransferase small domain Ubie_methyltran PF01209.18 KXL50596.1 - 0.047 13.0 0.0 0.085 12.2 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_33 PF10017.9 KXL50596.1 - 0.1 11.8 0.0 0.21 10.7 0.0 1.4 1 1 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Methyltransf_32 PF13679.6 KXL50596.1 - 0.14 12.2 0.1 0.35 10.8 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain PH PF00169.29 KXL50597.1 - 5e-10 39.8 1.0 6.1e-09 36.3 0.2 2.4 2 0 0 2 2 2 1 PH domain SAM_2 PF07647.17 KXL50597.1 - 1.6e-06 28.1 0.0 3.3e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.6 KXL50597.1 - 0.0065 16.9 0.5 0.016 15.6 0.5 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain SAM_1 PF00536.30 KXL50597.1 - 0.012 16.0 0.1 0.036 14.5 0.0 1.9 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) DUF4596 PF15363.6 KXL50597.1 - 0.12 12.6 0.3 0.61 10.4 0.3 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) Fungal_trans_2 PF11951.8 KXL50598.1 - 1.1e-84 284.5 0.1 1.4e-84 284.1 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL50598.1 - 1.9e-06 27.9 9.0 3.6e-06 27.0 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Focadhesin PF11229.8 KXL50598.1 - 0.01 14.2 0.0 0.014 13.6 0.0 1.1 1 0 0 1 1 1 1 Focadhesin Adaptin_N PF01602.20 KXL50600.1 - 2e-85 287.4 0.0 5.6e-85 285.9 0.0 1.6 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KXL50600.1 - 5.6e-06 26.5 2.7 0.00047 20.2 0.0 2.7 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXL50600.1 - 8.2e-05 22.9 2.5 1.3 9.5 0.0 4.1 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 KXL50600.1 - 0.0033 17.5 0.1 20 5.8 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 KXL50600.1 - 0.018 15.6 1.1 19 5.9 0.0 5.0 5 0 0 5 5 5 0 HEAT-like repeat AP3D1 PF06375.11 KXL50600.1 - 0.066 13.4 0.2 0.066 13.4 0.2 3.4 2 1 1 3 3 3 0 AP-3 complex subunit delta-1 Med19 PF10278.9 KXL50600.1 - 8.5 6.3 15.7 1.6e+02 2.1 15.7 2.4 1 1 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Velvet PF11754.8 KXL50601.1 - 1.5e-86 290.4 0.0 1.7e-86 290.3 0.0 1.0 1 0 0 1 1 1 1 Velvet factor SHR-BD PF06650.12 KXL50601.1 - 0.056 12.8 0.0 0.083 12.3 0.0 1.2 1 0 0 1 1 1 0 SHR-binding domain of vacuolar-sorting associated protein 13 WD40 PF00400.32 KXL50602.1 - 5.5e-14 52.3 0.0 5.8e-12 45.9 0.0 2.6 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL50602.1 - 4.6e-06 26.8 0.0 7.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXL50602.1 - 0.00011 21.3 0.0 0.00016 20.8 0.0 1.2 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KXL50602.1 - 0.038 13.9 0.0 0.088 12.8 0.0 1.6 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat HET-s_218-289 PF11558.8 KXL50603.1 - 0.012 15.6 0.1 0.02 14.9 0.1 1.3 1 0 0 1 1 1 0 Het-s 218-289 AAA_16 PF13191.6 KXL50603.1 - 0.049 14.0 0.0 0.11 12.9 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain APS_kinase PF01583.20 KXL50603.1 - 0.052 13.5 0.3 0.076 12.9 0.3 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Dynein_C PF18199.1 KXL50603.1 - 0.12 11.6 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Dynein heavy chain C-terminal domain NB-ARC PF00931.22 KXL50603.1 - 0.27 10.4 0.0 0.63 9.2 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain MFS_1 PF07690.16 KXL50606.1 - 1.6e-29 103.0 29.1 1.6e-29 103.0 29.1 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Wzy_C PF04932.15 KXL50606.1 - 4.3 6.9 8.7 0.41 10.3 0.2 3.0 2 1 0 2 2 2 0 O-Antigen ligase Ribosomal_L1 PF00687.21 KXL50607.1 - 2.4e-31 109.1 0.0 2.8e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family NUDIX PF00293.28 KXL50608.1 - 1.8e-14 53.9 0.1 3.6e-14 52.9 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 KXL50608.1 - 9.4e-14 51.9 0.1 2.7e-13 50.5 0.1 1.8 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 KXL50608.1 - 2.8e-07 30.1 0.3 4.7e-07 29.4 0.3 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain COG2 PF06148.11 KXL50609.1 - 5.4e-21 75.1 0.0 1.1e-20 74.1 0.0 1.5 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 CENP-B_dimeris PF09026.10 KXL50609.1 - 0.0078 16.6 1.3 0.018 15.4 1.3 1.6 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Pox_Ag35 PF03286.14 KXL50609.1 - 0.029 14.2 3.0 2.5 7.8 0.1 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein tRNA-synt_1c PF00749.21 KXL50610.1 - 1.3e-114 382.3 0.4 1.9e-114 381.8 0.4 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KXL50610.1 - 1.6e-30 106.2 0.5 3.7e-30 105.1 0.5 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Transglut_core PF01841.19 KXL50610.1 - 2.4e-07 31.2 0.4 8.2e-07 29.5 0.4 2.0 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.17 KXL50610.1 - 2.7e-05 23.8 0.0 0.0001 21.9 0.0 2.1 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXL50610.1 - 0.0015 18.1 0.1 0.0015 18.1 0.1 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KXL50610.1 - 0.3 11.0 0.9 0.65 9.9 0.1 2.1 2 0 0 2 2 2 0 Variant SH3 domain Glyco_hydro_53 PF07745.13 KXL50611.1 - 2.5e-05 23.4 0.0 2.9e-05 23.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 TERF2_RBM PF16772.5 KXL50611.1 - 0.044 13.2 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 Telomeric repeat-binding factor 2 Rap1-binding motif Glyco_hydro_53 PF07745.13 KXL50613.1 - 6.6e-62 209.5 0.1 7.6e-62 209.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 DUF1414 PF07208.11 KXL50613.1 - 0.059 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1414) DUF3425 PF11905.8 KXL50614.1 - 1.7e-19 70.0 0.4 1.7e-19 70.0 0.4 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3425) HCR PF07111.12 KXL50614.1 - 0.0046 15.1 1.4 0.007 14.5 1.4 1.2 1 0 0 1 1 1 1 Alpha helical coiled-coil rod protein (HCR) bZIP_1 PF00170.21 KXL50614.1 - 0.023 14.8 6.0 0.023 14.8 6.0 2.1 2 0 0 2 2 2 0 bZIP transcription factor BMFP PF04380.13 KXL50614.1 - 0.55 10.7 5.8 0.076 13.5 1.6 1.8 2 0 0 2 2 2 0 Membrane fusogenic activity Hexapep PF00132.24 KXL50615.1 - 1.5e-14 53.0 16.5 0.00058 19.5 2.1 5.3 5 0 0 5 5 5 5 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KXL50615.1 - 5.6e-06 26.0 14.6 0.0012 18.5 0.2 4.3 3 2 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KXL50615.1 - 0.081 11.0 1.9 0.12 10.5 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Acetyltransf_2 PF00797.17 KXL50618.1 - 1.8e-36 126.1 0.0 4.8e-36 124.8 0.0 1.6 1 1 0 1 1 1 1 N-acetyltransferase Transglut_core PF01841.19 KXL50618.1 - 0.0022 18.4 0.0 0.0039 17.6 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF728 PF05304.12 KXL50618.1 - 0.051 13.4 0.0 0.089 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF728) Pmp3 PF01679.17 KXL50620.1 - 9.4e-22 77.0 10.3 1.2e-21 76.7 10.3 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Pkinase PF00069.25 KXL50621.1 - 4.9e-71 239.2 0.0 8.6e-71 238.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL50621.1 - 5.3e-35 121.0 0.0 1.2e-34 119.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXL50621.1 - 0.00014 21.3 0.1 0.00073 18.9 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KXL50621.1 - 0.00045 19.3 0.1 0.023 13.7 0.0 2.3 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KXL50621.1 - 0.0042 16.5 0.3 0.0097 15.3 0.3 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXL50621.1 - 0.023 13.5 0.1 0.047 12.5 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase GTP_cyclohydroI PF01227.22 KXL50622.1 - 4.8e-74 247.6 0.4 6.4e-74 247.2 0.4 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KXL50622.1 - 0.0024 18.0 0.0 0.0059 16.7 0.0 1.6 1 0 0 1 1 1 1 QueF-like protein Glyco_hydro_43 PF04616.14 KXL50624.1 - 8.9e-49 166.3 0.1 1.2e-48 165.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KXL50624.1 - 9.5e-15 54.9 0.0 1.4e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DUF5005 PF16396.5 KXL50624.1 - 0.005 15.6 0.0 0.012 14.4 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF5005) Fungal_trans PF04082.18 KXL50625.1 - 4.4e-17 62.0 0.1 9e-17 61.0 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KXL50625.1 - 2.4e-08 34.0 12.0 0.0003 21.1 2.8 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXL50625.1 - 2e-05 25.0 8.9 0.012 16.4 1.1 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXL50625.1 - 8.1e-05 22.9 3.7 8.1e-05 22.9 3.7 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KXL50625.1 - 0.00031 20.7 6.3 0.0059 16.6 0.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXL50625.1 - 0.00099 19.3 2.7 0.097 13.0 0.3 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXL50625.1 - 0.0079 16.6 2.4 0.032 14.6 0.6 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-CRD PF17979.1 KXL50625.1 - 0.094 12.8 2.3 0.19 11.8 2.3 1.5 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions FYVE PF01363.21 KXL50625.1 - 0.37 11.0 5.1 0.83 9.8 5.1 1.5 1 0 0 1 1 1 0 FYVE zinc finger zf-C2H2_11 PF16622.5 KXL50625.1 - 3.3 7.6 7.8 7.2 6.5 1.1 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type Sugar_tr PF00083.24 KXL50626.1 - 1.3e-56 192.4 20.9 1.5e-56 192.2 20.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL50626.1 - 1.2e-12 47.4 31.2 1.2e-12 47.4 31.2 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily PsbJ PF01788.17 KXL50626.1 - 1.1 9.2 8.1 1.7 8.6 2.5 3.0 1 1 1 2 2 2 0 PsbJ Bac_rhamnosid6H PF17389.2 KXL50627.1 - 4.7e-14 52.4 0.0 7.3e-10 38.6 0.0 4.2 4 1 0 4 4 4 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 KXL50627.1 - 8.3e-11 41.5 0.4 9.1e-10 38.2 0.4 2.5 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain GDE_C PF06202.14 KXL50627.1 - 0.0011 18.0 0.0 0.022 13.7 0.0 2.3 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase RsfS PF02410.15 KXL50629.1 - 3.7e-13 49.7 0.0 1.1e-12 48.2 0.0 1.8 1 1 0 1 1 1 1 Ribosomal silencing factor during starvation Ribosomal_S5_C PF03719.15 KXL50631.1 - 2.7e-21 74.8 0.1 6.4e-21 73.6 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KXL50631.1 - 7.8e-18 64.2 0.1 1.6e-17 63.2 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Clr2_transil PF16761.5 KXL50632.1 - 9.6e-26 90.4 0.6 1.9e-25 89.5 0.6 1.5 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 KXL50632.1 - 4.3e-18 66.5 0.2 1e-16 62.0 0.1 2.7 2 1 0 2 2 2 1 Transcription-silencing protein Clr2 SNF2_N PF00176.23 KXL50633.1 - 1.1e-56 192.0 0.3 1.6e-56 191.5 0.3 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXL50633.1 - 2.8e-14 53.4 0.2 5.2e-13 49.3 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KXL50633.1 - 4.6e-07 29.3 0.0 1.5e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 KXL50633.1 - 2.8e-06 27.4 0.0 9.4e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PHD PF00628.29 KXL50633.1 - 1.9e-05 24.5 6.7 1.9e-05 24.5 6.7 2.7 3 0 0 3 3 3 1 PHD-finger zf-PHD-like PF15446.6 KXL50633.1 - 0.21 11.2 14.7 0.16 11.6 4.2 2.9 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PT PF04886.12 KXL50634.1 - 9.3e-06 25.1 5.6 2.5e-05 23.7 5.6 1.7 1 0 0 1 1 1 1 PT repeat ChuX_HutX PF06228.13 KXL50634.1 - 0.072 12.9 0.2 0.14 11.9 0.1 1.5 1 1 0 1 1 1 0 Haem utilisation ChuX/HutX Ferric_reduct PF01794.19 KXL50636.1 - 9.7e-19 67.7 10.5 2.9e-18 66.2 10.5 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXL50636.1 - 3.5e-18 66.2 0.0 5.4e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXL50636.1 - 4.3e-08 33.2 0.0 8.7e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KXL50636.1 - 0.00062 20.4 0.0 1.5 9.5 0.0 2.6 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain Man-6-P_recep PF02157.15 KXL50637.1 - 5.8e-17 61.6 0.0 1e-15 57.6 0.0 2.1 1 1 1 2 2 2 1 Mannose-6-phosphate receptor ATG27 PF09451.10 KXL50637.1 - 5.9e-09 36.2 0.0 1.7e-08 34.6 0.0 1.7 2 0 0 2 2 2 1 Autophagy-related protein 27 CIMR PF00878.18 KXL50637.1 - 2.4e-05 24.4 0.0 0.0022 18.1 0.0 2.3 2 1 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ADH_zinc_N_2 PF13602.6 KXL50638.1 - 8.8e-26 91.5 0.0 1.5e-25 90.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXL50638.1 - 6.8e-19 68.1 0.1 1.2e-18 67.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PHD PF00628.29 KXL50639.1 - 8e-12 44.9 4.8 1.6e-11 43.9 4.8 1.5 1 0 0 1 1 1 1 PHD-finger zf-CpG_bind_C PF12269.8 KXL50639.1 - 2.4e-06 27.5 1.1 5e-06 26.5 0.2 1.9 1 1 1 2 2 2 1 CpG binding protein zinc finger C terminal domain Secretin_N_2 PF07655.13 KXL50641.1 - 4.7 7.8 8.3 7.3 7.2 8.3 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain Lipase_3 PF01764.25 KXL50642.1 - 8.9e-18 64.5 0.0 1.3e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KXL50642.1 - 0.0034 18.0 0.8 0.0056 17.3 0.5 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family FBPase PF00316.20 KXL50643.1 - 2.1e-70 236.0 0.2 2.7e-70 235.7 0.2 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 KXL50643.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Inositol monophosphatase family APH PF01636.23 KXL50644.1 - 9.5e-13 48.6 0.0 1.9e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KXL50644.1 - 0.0031 16.9 0.0 0.0046 16.3 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Gpr1_Fun34_YaaH PF01184.19 KXL50646.1 - 5.3e-35 120.9 18.0 6.5e-35 120.6 18.0 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3437 PF11919.8 KXL50647.1 - 3.9e-30 103.6 0.0 3.2e-29 100.7 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) BLM10_mid PF16507.5 KXL50647.1 - 3.8e-21 75.4 0.1 2.4e-20 72.7 0.0 2.0 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, mid region HEAT_2 PF13646.6 KXL50647.1 - 0.00025 21.4 0.6 1.9 9.0 0.0 4.6 5 0 0 5 5 5 2 HEAT repeats HEAT PF02985.22 KXL50647.1 - 0.002 18.3 0.6 4.5 7.8 0.1 5.1 5 0 0 5 5 5 1 HEAT repeat Sod_Fe_C PF02777.18 KXL50648.1 - 2e-37 127.4 0.6 4.1e-37 126.4 0.6 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KXL50648.1 - 7.8e-30 103.2 2.1 7.8e-30 103.2 2.1 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF1751 PF08551.10 KXL50649.1 - 0.00064 20.2 1.8 0.00064 20.2 1.8 1.9 1 1 1 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 KXL50649.1 - 0.00095 19.2 2.2 0.0017 18.4 2.2 1.5 1 0 0 1 1 1 1 Rhomboid family Ribosomal_L7Ae PF01248.26 KXL50650.1 - 2e-21 75.5 0.7 3e-21 74.9 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Sld5 PF05916.11 KXL50651.1 - 6.6e-18 65.2 0.0 8.4e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein BLM10_mid PF16507.5 KXL50652.1 - 2.7e-189 630.2 0.0 3.4e-189 629.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region BLM10_N PF16547.5 KXL50652.1 - 7.8e-18 64.5 0.0 1.8e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal MOZ_SAS PF01853.18 KXL50652.1 - 0.1 12.2 0.1 0.25 11.0 0.1 1.6 1 0 0 1 1 1 0 MOZ/SAS family UCR_hinge PF02320.16 KXL50653.1 - 6e-25 87.2 12.4 1e-24 86.5 12.4 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Sigma70_ner PF04546.13 KXL50653.1 - 0.0051 16.7 8.7 0.0066 16.4 8.7 1.3 1 0 0 1 1 1 1 Sigma-70, non-essential region Nop14 PF04147.12 KXL50653.1 - 0.15 10.3 19.9 0.17 10.1 19.9 1.0 1 0 0 1 1 1 0 Nop14-like family Use1 PF09753.9 KXL50653.1 - 0.15 11.7 4.0 0.19 11.4 4.0 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 CDC45 PF02724.14 KXL50653.1 - 0.21 9.9 10.6 0.24 9.6 10.6 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2052 PF09747.9 KXL50653.1 - 0.51 10.4 15.6 0.64 10.1 15.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SpoIIIAH PF12685.7 KXL50653.1 - 1.6 8.5 10.3 1.9 8.2 10.3 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein RR_TM4-6 PF06459.12 KXL50653.1 - 2.4 7.9 12.2 2.9 7.6 12.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.8 KXL50653.1 - 2.9 6.6 8.1 3.4 6.4 8.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TRAP_alpha PF03896.16 KXL50653.1 - 8.7 5.4 9.0 10 5.2 9.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DNA_pol_phi PF04931.13 KXL50653.1 - 9.6 4.2 22.2 12 3.9 22.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi LPMO_10 PF03067.15 KXL50655.1 - 5.9e-14 53.2 0.3 8.2e-14 52.7 0.3 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Complex1_51K PF01512.17 KXL50657.1 - 3.2e-46 157.0 0.0 5.1e-46 156.3 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KXL50657.1 - 1.3e-28 98.9 0.5 2.7e-28 97.8 0.5 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KXL50657.1 - 2.7e-09 36.7 0.0 6.4e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 SLBB domain SHR-BD PF06650.12 KXL50658.1 - 1.7e-94 316.2 0.0 8.5e-94 313.9 0.0 2.2 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 KXL50658.1 - 1.2e-93 312.9 7.3 2.5e-88 295.5 0.1 5.4 6 0 0 6 6 6 3 Repeating coiled region of VPS13 VPS13 PF16908.5 KXL50658.1 - 1.6e-82 276.9 0.8 2.2e-81 273.1 0.0 3.2 4 0 0 4 4 4 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 KXL50658.1 - 6e-74 247.7 4.7 3.8e-69 232.0 0.3 2.6 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 KXL50658.1 - 3.6e-40 136.7 0.0 1.2e-39 135.1 0.0 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 KXL50658.1 - 7.8e-09 35.8 0.2 2.8e-07 30.8 0.0 3.2 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain CENP-T_N PF16171.5 KXL50658.1 - 0.037 13.0 0.1 0.1 11.5 0.1 1.7 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T N-terminus DUF896 PF05979.12 KXL50658.1 - 0.062 13.2 6.5 0.6 10.0 0.4 3.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) DUF3429 PF11911.8 KXL50659.1 - 6.7e-42 143.2 10.9 8.8e-42 142.8 10.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) adh_short PF00106.25 KXL50660.1 - 3.2e-33 114.8 0.0 4.3e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL50660.1 - 2.6e-23 82.8 0.0 3.4e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL50660.1 - 1.2e-05 25.3 0.1 2e-05 24.6 0.1 1.4 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KXL50660.1 - 0.17 12.2 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Drf_GBD PF06371.13 KXL50661.1 - 4.2e-17 62.3 0.1 3.2e-15 56.2 0.1 2.4 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain Sugar_tr PF00083.24 KXL50662.1 - 3.7e-75 253.5 27.7 4.2e-75 253.3 27.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL50662.1 - 3.6e-21 75.5 23.7 3.6e-21 75.5 23.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXL50662.1 - 3.5e-06 25.8 0.8 3.5e-06 25.8 0.8 2.2 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.16 KXL50662.1 - 0.0017 16.7 0.9 0.0017 16.7 0.9 2.1 2 1 0 2 2 2 1 BT1 family Glyco_hyd_65N_2 PF14498.6 KXL50663.1 - 6.2e-65 219.4 0.0 9.1e-65 218.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Pro_dh PF01619.18 KXL50664.1 - 2e-60 204.9 0.3 2.8e-60 204.3 0.3 1.2 1 0 0 1 1 1 1 Proline dehydrogenase Hydrolase_6 PF13344.6 KXL50666.1 - 1.3e-29 102.2 0.0 2.4e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXL50666.1 - 7e-14 51.6 0.0 1.3e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KXL50666.1 - 6.8e-11 42.9 0.0 1e-10 42.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXL50666.1 - 0.00028 21.0 0.2 0.14 12.2 0.0 2.5 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase MFS_1 PF07690.16 KXL50667.1 - 1.7e-28 99.6 24.5 1.7e-28 99.6 24.5 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3397 PF11877.8 KXL50667.1 - 0.029 14.6 5.5 0.61 10.3 1.5 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3397) DUF4448 PF14610.6 KXL50667.1 - 4.8 6.9 4.3 1.6 8.5 0.4 2.3 3 1 0 3 3 3 0 Protein of unknown function (DUF4448) Peptidase_S58 PF03576.14 KXL50668.1 - 1.3e-77 261.3 1.7 1.6e-77 261.0 1.7 1.0 1 0 0 1 1 1 1 Peptidase family S58 Methyltransf_11 PF08241.12 KXL50669.1 - 0.00027 21.5 0.0 0.00063 20.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL50669.1 - 0.017 15.8 0.0 0.047 14.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.16 KXL50672.1 - 2.2e-09 36.7 33.2 2.2e-09 36.7 33.2 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TFR_dimer PF04253.15 KXL50673.1 - 4.5e-31 107.5 0.0 7.8e-31 106.7 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KXL50673.1 - 1.6e-22 80.1 0.0 3.4e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Slx4 PF09494.10 KXL50674.1 - 2.2e-18 66.0 4.6 5.4e-18 64.7 4.6 1.7 1 1 0 1 1 1 1 Slx4 endonuclease Amidohydro_1 PF01979.20 KXL50676.1 - 4.8e-33 114.9 0.2 5.8e-33 114.6 0.2 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXL50676.1 - 3.9e-08 33.2 0.1 5.8e-08 32.6 0.1 1.4 1 1 0 1 1 1 1 Amidohydrolase family Urocanase_C PF17392.2 KXL50676.1 - 0.13 11.7 0.2 0.27 10.6 0.1 1.5 2 0 0 2 2 2 0 Urocanase C-terminal domain CAP PF00188.26 KXL50677.1 - 2e-15 57.7 2.1 2e-15 57.7 2.1 1.7 2 0 0 2 2 2 1 Cysteine-rich secretory protein family BASP1 PF05466.12 KXL50677.1 - 2.1 8.3 14.5 3.7 7.5 14.5 1.4 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) Sporozoite_P67 PF05642.11 KXL50677.1 - 7.1 4.6 10.8 9.2 4.2 10.8 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Med3 PF11593.8 KXL50677.1 - 9.9 5.2 11.7 14 4.7 11.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Thioredox_DsbH PF03190.15 KXL50678.1 - 3.7e-67 225.3 0.0 6.5e-67 224.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 KXL50678.1 - 3.9e-08 33.4 0.0 1e-06 28.8 0.0 3.0 3 0 0 3 3 3 1 Thioredoxin-like Glyco_hydro_76 PF03663.14 KXL50678.1 - 0.0056 16.2 3.1 0.027 14.0 0.9 2.8 2 1 1 3 3 3 2 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KXL50678.1 - 0.025 13.6 0.1 2 7.4 0.1 2.6 2 1 0 2 2 2 0 Glycosyl Hydrolase Family 88 Sigma70_r3 PF04539.16 KXL50678.1 - 0.11 12.6 0.1 0.4 10.8 0.1 2.0 2 0 0 2 2 2 0 Sigma-70 region 3 NIF PF03031.18 KXL50679.1 - 2.2e-24 86.0 0.4 3e-24 85.6 0.4 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase RNA_pol_Rpb2_6 PF00562.28 KXL50680.1 - 9e-121 403.6 0.1 1.3e-120 403.0 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KXL50680.1 - 1.4e-49 168.4 0.1 2.4e-49 167.6 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KXL50680.1 - 7.6e-34 116.0 1.2 1.8e-33 114.8 1.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 KXL50680.1 - 2.1e-29 102.5 0.1 3.9e-29 101.6 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 KXL50680.1 - 8.4e-25 86.8 0.3 2.2e-24 85.5 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KXL50680.1 - 3.6e-18 65.5 0.1 7.8e-18 64.4 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KXL50680.1 - 4.1e-09 36.9 0.4 1.3e-08 35.2 0.4 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 PUF PF00806.19 KXL50681.1 - 4.5e-59 192.9 8.9 3.5e-08 32.7 0.4 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 KXL50681.1 - 0.03 14.7 2.5 5 7.5 0.5 3.9 1 1 2 3 3 3 0 CPL (NUC119) domain Ycf1 PF05758.12 KXL50681.1 - 0.045 11.6 0.0 0.072 11.0 0.0 1.2 1 0 0 1 1 1 0 Ycf1 HEXIM PF15313.6 KXL50681.1 - 0.11 12.6 0.0 0.71 10.1 0.0 2.4 1 0 0 1 1 1 0 Hexamethylene bis-acetamide-inducible protein MgtE_N PF03448.17 KXL50681.1 - 0.15 12.6 1.6 0.19 12.3 0.2 1.9 2 0 0 2 2 2 0 MgtE intracellular N domain SRI PF08236.11 KXL50685.1 - 1.6e-17 63.4 12.6 1.6e-17 63.4 12.6 2.2 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 KXL50685.1 - 1.8e-17 64.2 0.3 1.8e-17 64.2 0.3 3.7 3 2 0 3 3 3 1 SET domain AWS PF17907.1 KXL50685.1 - 6.1e-10 39.0 8.7 6.1e-10 39.0 8.7 2.3 3 0 0 3 3 3 1 AWS domain Med26 PF08711.11 KXL50685.1 - 3.7e-09 36.5 0.5 1.4e-08 34.6 0.5 2.1 1 0 0 1 1 1 1 TFIIS helical bundle-like domain WW PF00397.26 KXL50685.1 - 6.5e-07 29.3 1.4 1.6e-06 28.1 1.4 1.7 1 0 0 1 1 1 1 WW domain K_channel_TID PF07941.11 KXL50687.1 - 0.049 14.1 4.1 0.049 14.1 4.1 2.1 2 1 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain HIG_1_N PF04588.13 KXL50689.1 - 7.2e-05 22.9 0.2 7.2e-05 22.9 0.2 1.9 2 0 0 2 2 2 1 Hypoxia induced protein conserved region Romo1 PF10247.9 KXL50689.1 - 0.0084 16.4 1.8 0.014 15.8 0.8 1.7 2 0 0 2 2 2 1 Reactive mitochondrial oxygen species modulator 1 ENOD93 PF03386.14 KXL50689.1 - 0.12 12.2 0.5 0.26 11.2 0.1 1.7 2 0 0 2 2 2 0 Early nodulin 93 ENOD93 protein eIF3_subunit PF08597.10 KXL50689.1 - 1.1 9.1 13.2 0.27 11.1 9.4 1.8 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit MotA_ExbB PF01618.16 KXL50689.1 - 9.3 6.0 13.1 0.63 9.8 2.3 3.1 3 1 0 4 4 4 0 MotA/TolQ/ExbB proton channel family RRP36 PF06102.12 KXL50690.1 - 7.1e-46 156.2 29.2 7.1e-46 156.2 29.2 2.4 2 1 0 2 2 2 1 rRNA biogenesis protein RRP36 DUF3684 PF12449.8 KXL50691.1 - 0 1395.1 0.0 0 1394.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 KXL50691.1 - 0.0002 21.2 0.0 0.00054 19.8 0.0 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WLM PF08325.10 KXL50691.1 - 0.01 16.0 0.8 0.28 11.2 0.2 2.4 2 0 0 2 2 2 1 WLM domain DUF1421 PF07223.11 KXL50691.1 - 0.13 12.1 0.0 0.39 10.6 0.0 1.9 1 0 0 1 1 1 0 UBA-like domain (DUF1421) CAS_CSE1 PF03378.15 KXL50692.1 - 7.2e-171 568.6 0.3 7.2e-171 568.6 0.3 1.8 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 KXL50692.1 - 3.4e-148 493.4 2.5 4.9e-148 492.9 2.5 1.2 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 KXL50692.1 - 5.9e-19 67.8 0.2 2.4e-18 65.8 0.2 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Glyco_transf_90 PF05686.12 KXL50692.1 - 0.13 11.2 0.0 0.26 10.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 90 RIIa PF02197.17 KXL50692.1 - 0.13 11.9 0.1 0.64 9.7 0.0 2.3 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit Glyco_hydro_47 PF01532.20 KXL50693.1 - 8.4e-169 562.3 0.0 9.7e-169 562.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Rep_fac_C PF08542.11 KXL50694.1 - 2.2e-24 85.7 0.0 5.5e-24 84.4 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KXL50694.1 - 2.8e-11 43.5 0.0 1.7e-08 34.4 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 KXL50694.1 - 3.8e-11 43.5 0.0 6.5e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KXL50694.1 - 1.4e-06 28.4 0.0 4.1e-06 26.9 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KXL50694.1 - 9.1e-06 26.1 0.0 0.00058 20.3 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 KXL50694.1 - 1.4e-05 25.0 0.0 2.2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KXL50694.1 - 8.4e-05 22.9 0.0 0.07 13.4 0.0 2.5 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.12 KXL50694.1 - 9e-05 22.3 0.0 0.00021 21.1 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 KXL50694.1 - 0.00041 20.2 0.0 0.00085 19.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 KXL50694.1 - 0.0013 18.5 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 KXL50694.1 - 0.0019 17.7 0.0 0.019 14.3 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 KXL50694.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain MeaB PF03308.16 KXL50694.1 - 0.015 14.3 0.0 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_11 PF13086.6 KXL50694.1 - 0.019 14.8 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_assoc_2 PF16193.5 KXL50694.1 - 0.019 15.3 0.0 0.053 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA C-terminal domain AAA_19 PF13245.6 KXL50694.1 - 0.019 15.3 0.1 0.075 13.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXL50694.1 - 0.029 14.1 0.0 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KXL50694.1 - 0.035 13.5 0.0 5.7 6.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein NTPase_1 PF03266.15 KXL50694.1 - 0.06 13.3 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 NTPase DEAD PF00270.29 KXL50694.1 - 0.091 12.5 0.1 1.4 8.6 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_30 PF13604.6 KXL50694.1 - 0.14 11.8 0.1 0.39 10.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain Mid1 PF12929.7 KXL50695.1 - 1.1e-158 528.9 6.9 1.3e-158 528.7 6.9 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 KXL50695.1 - 0.00092 19.8 7.3 0.24 12.0 2.7 2.7 2 1 0 2 2 2 2 Fz domain CPBP PF02517.16 KXL50696.1 - 2.2e-14 53.6 10.6 2.2e-14 53.6 10.6 2.7 1 1 1 2 2 2 1 CPBP intramembrane metalloprotease Spt4 PF06093.13 KXL50698.1 - 9.7e-33 112.1 0.1 1.2e-32 111.8 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger PPP5 PF08321.12 KXL50699.1 - 5.1e-34 116.4 2.2 8.1e-34 115.8 0.5 2.1 2 0 0 2 2 2 1 PPP5 TPR repeat region Metallophos PF00149.28 KXL50699.1 - 1.3e-31 110.7 0.0 2.3e-31 109.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 KXL50699.1 - 3.2e-17 61.5 0.9 6.6e-06 25.7 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXL50699.1 - 7.2e-10 38.2 2.1 0.0045 17.0 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXL50699.1 - 1.8e-08 33.9 1.6 0.0035 17.0 0.1 2.6 1 1 1 2 2 2 2 TPR repeat TPR_17 PF13431.6 KXL50699.1 - 1.1e-05 25.4 0.6 0.26 11.8 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXL50699.1 - 0.0003 21.4 0.3 0.0057 17.3 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXL50699.1 - 0.015 15.5 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXL50699.1 - 0.19 12.0 9.6 0.64 10.4 0.1 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3328 PF11807.8 KXL50700.1 - 4.5e-28 98.5 0.0 7.9e-28 97.7 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) AA_permease PF00324.21 KXL50701.1 - 1.6e-54 185.3 31.8 8.4e-34 117.0 14.8 3.0 1 1 2 3 3 3 3 Amino acid permease AA_permease_2 PF13520.6 KXL50701.1 - 2.7e-07 29.8 14.7 2.7e-07 29.8 14.7 2.9 2 1 1 3 3 3 3 Amino acid permease NapE PF06796.11 KXL50701.1 - 0.23 11.0 0.1 0.23 11.0 0.1 2.4 3 0 0 3 3 3 0 Periplasmic nitrate reductase protein NapE MNSV_P7B PF06692.11 KXL50701.1 - 0.58 10.2 0.1 0.58 10.2 0.1 4.5 5 0 0 5 5 5 0 Melon necrotic spot virus P7B protein Proteasome PF00227.26 KXL50702.1 - 1.5e-55 187.7 0.1 2e-55 187.2 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXL50702.1 - 1.8e-12 46.7 0.0 3.7e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature GCP_N_terminal PF17681.1 KXL50703.1 - 5.7e-71 239.6 0.1 1.7e-70 238.1 0.0 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KXL50703.1 - 2.4e-63 214.4 3.0 2.4e-63 214.4 3.0 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal FA_desaturase PF00487.24 KXL50704.1 - 2.3e-23 83.3 21.0 4.9e-23 82.3 21.0 1.4 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KXL50704.1 - 1e-06 28.9 0.0 2.4e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Meth_synt_2 PF01717.18 KXL50706.1 - 5.4e-19 68.6 0.0 4.7e-13 49.1 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KXL50706.1 - 0.00035 20.2 0.0 0.033 13.7 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain ADH_zinc_N PF00107.26 KXL50707.1 - 0.00017 21.5 0.1 0.00033 20.6 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXL50707.1 - 0.0039 18.3 0.0 0.0084 17.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Abhydrolase_6 PF12697.7 KXL50709.1 - 1.8e-11 45.1 0.1 2.6e-11 44.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXL50709.1 - 1e-07 31.5 0.0 1.7e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXL50709.1 - 0.00046 19.9 0.0 0.00072 19.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KXL50709.1 - 0.068 12.1 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Esterase PF00756.20 KXL50709.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Ndr PF03096.14 KXL50709.1 - 0.19 10.4 0.0 0.27 9.9 0.0 1.2 1 0 0 1 1 1 0 Ndr family DUF202 PF02656.15 KXL50711.1 - 0.0037 17.7 10.5 0.17 12.4 10.5 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF202) Myelin_PLP PF01275.19 KXL50711.1 - 0.059 13.2 1.1 0.073 12.9 1.1 1.1 1 0 0 1 1 1 0 Myelin proteolipid protein (PLP or lipophilin) Col_cuticle_N PF01484.17 KXL50713.1 - 0.071 13.2 0.3 0.11 12.6 0.3 1.3 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain Peptidase_A4 PF01828.17 KXL50714.1 - 2.3e-78 262.4 12.6 2.8e-78 262.2 12.6 1.1 1 0 0 1 1 1 1 Peptidase A4 family Polysacc_deac_1 PF01522.21 KXL50715.1 - 2e-15 56.8 0.1 8.9e-15 54.7 0.1 1.9 1 1 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KXL50715.1 - 0.066 12.9 0.0 0.41 10.3 0.0 2.1 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) ADH_zinc_N_2 PF13602.6 KXL50716.1 - 2.1e-17 64.4 0.0 4.2e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXL50716.1 - 3e-14 53.1 0.8 5.1e-14 52.4 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXL50716.1 - 1.4e-06 28.1 0.4 0.0025 17.7 0.0 3.0 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KXL50716.1 - 0.0016 18.3 0.0 0.0046 16.8 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase DUF3431 PF11913.8 KXL50717.1 - 3.4e-64 216.6 0.0 4.2e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Ceramidase PF05875.12 KXL50718.1 - 5.2e-79 265.4 9.1 6.1e-79 265.1 9.1 1.0 1 0 0 1 1 1 1 Ceramidase DUF4233 PF14017.6 KXL50718.1 - 0.017 15.4 1.0 0.017 15.4 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) Arv1 PF04161.13 KXL50718.1 - 0.021 15.0 1.4 0.031 14.5 1.4 1.4 1 0 0 1 1 1 0 Arv1-like family DUF3302 PF11742.8 KXL50718.1 - 0.089 12.9 2.8 0.12 12.5 0.8 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3302) DUF2085 PF09858.9 KXL50718.1 - 0.7 10.4 8.3 0.21 12.1 3.2 2.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2085) Sugar_tr PF00083.24 KXL50719.1 - 5.5e-75 253.0 23.5 6.3e-75 252.7 23.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL50719.1 - 1.3e-12 47.3 26.8 1.3e-12 47.3 26.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXL50719.1 - 3.2e-05 22.7 17.5 0.0023 16.6 4.3 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 KXL50719.1 - 0.0014 17.6 14.8 0.017 14.0 7.5 2.3 2 0 0 2 2 2 2 MFS_1 like family Phage_holin_7_1 PF16081.5 KXL50719.1 - 0.18 12.0 1.0 0.43 10.7 1.0 1.6 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family DDE_1 PF03184.19 KXL50720.1 - 0.0067 16.1 0.0 0.0077 15.9 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Acetyltransf_7 PF13508.7 KXL50721.1 - 0.0001 22.7 0.0 0.00028 21.3 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXL50721.1 - 0.0043 17.0 0.4 0.2 11.6 0.4 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXL50721.1 - 0.093 13.0 0.2 0.59 10.4 0.1 2.1 2 1 0 2 2 2 0 Acetyltransferase (GNAT) family MARVEL PF01284.23 KXL50722.1 - 0.051 13.6 2.6 0.57 10.2 1.4 2.6 2 1 0 2 2 2 0 Membrane-associating domain DUF4131 PF13567.6 KXL50722.1 - 0.42 10.3 3.7 0.31 10.7 1.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) RNA_pol_Rpc34 PF05158.12 KXL50723.1 - 1.6e-72 244.7 0.0 1.9e-72 244.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit GYR PF02756.14 KXL50723.1 - 0.092 12.5 0.1 0.26 11.0 0.1 1.8 1 0 0 1 1 1 0 GYR motif DUF1989 PF09347.10 KXL50724.1 - 1.7e-40 138.4 0.0 1.9e-30 105.7 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1989) CDC45 PF02724.14 KXL50724.1 - 4.2 5.6 8.4 7.7 4.7 8.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Acetyltransf_8 PF13523.6 KXL50725.1 - 2.7e-51 173.0 0.1 4e-51 172.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KXL50725.1 - 0.0053 17.4 0.0 0.0096 16.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DDE_1 PF03184.19 KXL50729.1 - 0.12 12.0 0.0 0.12 12.0 0.0 1.0 1 0 0 1 1 1 0 DDE superfamily endonuclease GFA PF04828.14 KXL50731.1 - 5e-15 55.6 2.1 7.7e-15 55.0 2.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme HalOD2 PF18547.1 KXL50731.1 - 0.0064 16.4 0.8 2.1 8.3 0.1 2.5 2 0 0 2 2 2 2 Halobacterial output domain 2 SelR PF01641.18 KXL50731.1 - 0.015 15.4 0.6 0.021 14.9 0.6 1.3 1 0 0 1 1 1 0 SelR domain DNA_RNApol_7kD PF03604.13 KXL50731.1 - 0.16 11.7 0.1 0.16 11.7 0.1 2.5 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit ING PF12998.7 KXL50732.1 - 2.2e-18 66.7 0.3 3.4e-18 66.1 0.3 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KXL50732.1 - 3.5e-05 23.6 9.0 5.7e-05 22.9 9.0 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KXL50732.1 - 0.0029 17.8 0.1 0.0057 16.9 0.1 1.4 1 0 0 1 1 1 1 PHD-like zinc-binding domain Cwf_Cwc_15 PF04889.12 KXL50732.1 - 0.054 13.2 2.7 0.11 12.2 2.7 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Hamartin PF04388.12 KXL50732.1 - 0.38 9.4 5.3 0.5 9.0 5.3 1.1 1 0 0 1 1 1 0 Hamartin protein zf-RING_2 PF13639.6 KXL50732.1 - 0.71 10.3 5.2 1.2 9.5 5.2 1.3 1 0 0 1 1 1 0 Ring finger domain SRP-alpha_N PF04086.13 KXL50732.1 - 3.5 7.5 9.1 5.1 6.9 9.1 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Hist_deacetyl PF00850.19 KXL50733.1 - 6.9e-74 249.1 0.0 9.5e-74 248.6 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain CCDC84 PF14968.6 KXL50733.1 - 0.26 10.9 1.2 0.39 10.3 1.2 1.2 1 0 0 1 1 1 0 Coiled coil protein 84 Esterase_phd PF10503.9 KXL50734.1 - 1.5e-07 31.2 0.0 1.2e-06 28.2 0.0 2.1 1 1 1 2 2 2 1 Esterase PHB depolymerase FSH1 PF03959.13 KXL50734.1 - 3.8e-06 26.7 0.0 4.9e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KXL50734.1 - 8.2e-05 22.5 0.0 0.00013 21.9 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.18 KXL50734.1 - 0.0077 15.8 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KXL50734.1 - 0.01 15.2 0.0 0.73 9.1 0.0 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 AXE1 PF05448.12 KXL50734.1 - 0.036 12.8 0.0 0.058 12.1 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Esterase PF00756.20 KXL50734.1 - 0.044 13.4 0.0 0.1 12.2 0.0 1.4 1 1 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 KXL50734.1 - 0.069 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXL50734.1 - 0.069 12.6 0.0 0.14 11.6 0.0 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family US6 PF17616.2 KXL50735.1 - 0.26 11.2 0.9 0.26 11.2 0.9 1.1 1 0 0 1 1 1 0 Viral unique short region 6 UL42 PF17638.2 KXL50735.1 - 0.26 11.2 1.4 0.35 10.9 1.3 1.3 1 1 0 1 1 1 0 HCMV UL42 UPF0086 PF01868.16 KXL50736.1 - 0.027 14.4 1.0 0.033 14.1 0.7 1.3 1 1 0 1 1 1 0 Domain of unknown function UPF0086 A_deaminase PF00962.22 KXL50738.1 - 1.4e-67 228.3 0.0 1.6e-67 228.2 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Fungal_trans_2 PF11951.8 KXL50739.1 - 6.1e-06 25.3 9.7 7.3e-06 25.0 5.4 2.5 2 1 1 3 3 3 2 Fungal specific transcription factor domain PHD PF00628.29 KXL50740.1 - 1.7e-06 27.8 4.2 3e-06 27.0 4.2 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KXL50740.1 - 0.0035 16.8 1.3 0.0078 15.7 1.3 1.6 1 0 0 1 1 1 1 PHD-finger FTHFS PF01268.19 KXL50741.1 - 2.5e-252 838.0 0.4 4.1e-252 837.3 0.2 1.4 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 KXL50741.1 - 1.8e-67 225.6 1.2 1.8e-67 225.6 1.2 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KXL50741.1 - 1.2e-36 125.5 0.5 3.4e-36 124.0 0.5 1.9 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 KXL50741.1 - 0.0084 15.1 0.1 0.018 14.0 0.1 1.5 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Helicase_C_4 PF13871.6 KXL50741.1 - 0.038 13.7 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain on Strawberry notch homologue WD40 PF00400.32 KXL50742.1 - 4.9e-25 87.3 0.4 2.8e-05 24.8 0.0 6.3 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL50742.1 - 6.5e-10 39.2 0.0 0.02 15.2 0.0 5.4 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXL50742.1 - 0.0018 18.2 0.1 0.28 11.1 0.0 2.6 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 KXL50742.1 - 0.015 14.4 0.0 0.69 8.9 0.0 2.5 2 1 0 3 3 3 0 Coatomer WD associated region Kelch_1 PF01344.25 KXL50742.1 - 0.033 13.8 0.5 0.72 9.5 0.3 2.4 2 0 0 2 2 2 0 Kelch motif WD40_like PF17005.5 KXL50742.1 - 0.034 13.5 0.0 0.61 9.4 0.0 2.5 2 1 1 3 3 3 0 WD40-like domain RNR_inhib PF08591.10 KXL50743.1 - 1.1e-26 94.2 0.6 2.3e-26 93.2 0.6 1.5 1 0 0 1 1 1 1 Ribonucleotide reductase inhibitor HEAT_EZ PF13513.6 KXL50744.1 - 7.9e-15 55.0 13.9 7.9e-09 35.8 0.0 9.1 7 3 3 10 10 9 3 HEAT-like repeat HEAT_2 PF13646.6 KXL50744.1 - 4.6e-13 49.4 10.1 0.00042 20.6 0.0 7.2 4 2 4 8 8 8 5 HEAT repeats HEAT PF02985.22 KXL50744.1 - 2.2e-12 46.1 19.4 0.00014 21.8 0.1 11.2 13 1 0 13 13 13 2 HEAT repeat IBN_N PF03810.19 KXL50744.1 - 3.2e-08 33.4 1.7 3.2e-08 33.4 1.7 3.7 4 0 0 4 4 4 1 Importin-beta N-terminal domain Cse1 PF08506.10 KXL50744.1 - 6.6e-05 21.9 0.1 0.21 10.4 0.1 3.2 3 0 0 3 3 3 2 Cse1 CLASP_N PF12348.8 KXL50744.1 - 9e-05 22.1 7.1 1.3 8.5 0.0 5.7 2 1 4 6 6 6 2 CLASP N terminal MMS19_C PF12460.8 KXL50744.1 - 0.00014 21.1 6.0 0.0041 16.3 4.5 3.3 2 1 0 2 2 2 1 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.7 KXL50744.1 - 0.00024 21.6 2.0 59 4.3 0.0 7.0 7 1 1 8 8 7 0 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 KXL50744.1 - 0.00061 19.7 3.6 1.9 8.4 0.0 4.3 3 1 1 4 4 4 2 Domain of unknown function (DUF3385) RIX1 PF08167.12 KXL50744.1 - 0.0024 17.6 7.4 5.4 6.7 1.2 4.9 2 2 2 4 4 4 2 rRNA processing/ribosome biogenesis Cnd1 PF12717.7 KXL50744.1 - 0.0036 17.4 1.3 0.056 13.5 0.1 3.4 2 1 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 KXL50744.1 - 0.0076 16.3 7.2 14 5.9 0.1 5.9 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 KXL50744.1 - 0.0082 16.7 3.4 42 5.2 0.0 6.0 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat Sec7_N PF12783.7 KXL50744.1 - 0.042 13.8 0.4 5.5 6.9 0.0 3.2 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Ribosomal_S9 PF00380.19 KXL50745.1 - 2.6e-43 147.4 0.0 4.1e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF1G PF00647.19 KXL50746.1 - 2.1e-45 153.2 0.0 3.6e-45 152.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 KXL50746.1 - 2.9e-12 46.7 3.7 3.7e-12 46.3 0.0 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXL50746.1 - 1.1e-09 38.5 0.0 6.9e-09 35.9 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXL50746.1 - 1.3e-05 25.3 0.0 1.3e-05 25.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXL50746.1 - 1.8e-05 24.7 0.0 5.1e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXL50746.1 - 0.00013 22.3 0.0 0.00027 21.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Pyridoxal_deC PF00282.19 KXL50747.1 - 1.3e-79 267.7 0.0 1.7e-79 267.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KXL50747.1 - 5.4e-05 22.3 0.0 9.6e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Fungal_trans PF04082.18 KXL50748.1 - 3.4e-20 72.2 1.3 3.9e-20 72.0 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL50748.1 - 9.3e-08 32.1 12.9 1.9e-07 31.1 12.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TRI12 PF06609.13 KXL50749.1 - 4.5e-56 190.5 16.6 6.1e-56 190.1 16.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KXL50749.1 - 2e-18 66.4 51.7 5.5e-17 61.7 50.0 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL50749.1 - 8.5e-08 31.5 6.7 8.5e-08 31.5 6.7 2.9 4 0 0 4 4 4 2 Sugar (and other) transporter AtuA PF07287.11 KXL50750.1 - 3.5e-128 427.2 0.2 4.5e-128 426.9 0.2 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Fungal_trans PF04082.18 KXL50751.1 - 1.4e-09 37.4 0.1 2.6e-09 36.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL50751.1 - 4e-08 33.2 10.5 7.9e-08 32.3 10.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KXL50752.1 - 1e-23 83.8 46.8 1e-23 83.8 46.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.25 KXL50754.1 - 7.5e-19 68.0 0.0 1.2e-14 54.2 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXL50754.1 - 3.9e-11 43.0 0.1 1.8e-09 37.5 0.1 2.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF963 PF06131.11 KXL50754.1 - 0.05 13.0 2.1 0.08 12.4 2.1 1.3 1 0 0 1 1 1 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) RNA_pol_I_A49 PF06870.12 KXL50755.1 - 1.2e-55 189.0 0.0 1.6e-55 188.6 0.0 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Alpha_GJ PF03229.13 KXL50755.1 - 0.28 11.7 3.4 0.99 10.0 3.4 1.9 1 0 0 1 1 1 0 Alphavirus glycoprotein J Promethin PF16015.5 KXL50756.1 - 1.2e-27 95.9 19.9 1.8e-27 95.3 19.9 1.3 1 0 0 1 1 1 1 Promethin DUF2207 PF09972.9 KXL50756.1 - 4.1 6.1 8.2 7.7 5.2 8.4 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) CAF1 PF04857.20 KXL50757.1 - 1.8e-20 73.4 0.0 3.3e-10 39.7 0.0 2.3 2 0 0 2 2 2 2 CAF1 family ribonuclease NIR_SIR_ferr PF03460.17 KXL50757.1 - 0.083 12.8 0.1 8.2 6.4 0.0 2.4 2 0 0 2 2 2 0 Nitrite/Sulfite reductase ferredoxin-like half domain NDUF_B12 PF08122.12 KXL50758.1 - 2.1e-24 85.3 0.5 3e-24 84.8 0.5 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Mito_carr PF00153.27 KXL50759.1 - 1.2e-65 217.4 2.3 1.3e-21 76.3 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.18 KXL50760.1 - 1.6e-08 34.0 3.7 2.4e-08 33.3 3.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL50760.1 - 8.6e-08 32.2 5.4 1.6e-07 31.3 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RPN7 PF10602.9 KXL50760.1 - 0.054 13.2 0.1 1.8 8.3 0.1 2.3 1 1 0 1 1 1 0 26S proteasome subunit RPN7 DICT PF10069.9 KXL50760.1 - 0.099 12.4 0.0 0.46 10.3 0.0 2.1 2 0 0 2 2 2 0 Sensory domain in DIguanylate Cyclases and Two-component system Epimerase PF01370.21 KXL50762.1 - 1.5e-24 86.8 0.0 2.2e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXL50762.1 - 2.8e-19 69.7 0.1 7.5e-15 55.1 0.0 2.7 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXL50762.1 - 8.6e-12 44.8 0.0 1.9e-08 33.8 0.0 2.9 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KXL50762.1 - 3.1e-10 39.7 0.0 4.8e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KXL50762.1 - 5.4e-09 35.5 0.0 8.1e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXL50762.1 - 7.5e-07 28.6 0.0 3.2e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 KXL50762.1 - 0.019 14.9 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding COesterase PF00135.28 KXL50763.1 - 1.7e-37 129.5 0.0 9.1e-22 77.6 0.1 2.2 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KXL50763.1 - 0.005 16.7 1.3 0.38 10.6 1.2 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF5119 PF17145.4 KXL50763.1 - 0.18 11.7 0.2 0.32 10.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5119) DAO PF01266.24 KXL50765.1 - 6.4e-05 22.7 0.1 0.12 11.9 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXL50765.1 - 0.0019 18.4 0.0 0.0044 17.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXL50765.1 - 0.0031 16.8 0.1 0.54 9.4 0.0 2.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXL50765.1 - 0.0066 15.7 0.0 0.025 13.9 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 KXL50765.1 - 0.12 11.2 0.0 0.25 10.2 0.0 1.5 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 KXL50765.1 - 0.15 11.2 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Hydrolase_3 PF08282.12 KXL50766.1 - 8.6e-12 45.3 0.0 1.6e-10 41.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PMM PF03332.13 KXL50766.1 - 5e-09 36.3 0.0 8.2e-09 35.6 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase PF00702.26 KXL50766.1 - 0.0011 19.3 0.0 0.0077 16.5 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KXL50766.1 - 0.0097 15.5 0.0 0.14 11.7 0.0 2.1 2 1 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase PNK3P PF08645.11 KXL50766.1 - 0.093 12.4 0.0 3.9 7.2 0.0 2.3 2 1 0 2 2 2 0 Polynucleotide kinase 3 phosphatase HAD_2 PF13419.6 KXL50766.1 - 0.14 12.2 0.0 1.4 9.0 0.0 2.2 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Fungal_trans PF04082.18 KXL50767.1 - 3.7e-14 52.4 1.5 1.2e-13 50.7 1.4 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL50767.1 - 9e-08 32.1 14.5 1.7e-07 31.3 14.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CENP-H PF05837.12 KXL50767.1 - 0.14 12.6 0.2 0.37 11.2 0.2 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) F-box-like PF12937.7 KXL50768.1 - 0.00013 21.7 0.1 0.00055 19.8 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KXL50769.1 - 0.11 12.5 1.0 1.3 9.0 0.3 2.3 2 0 0 2 2 2 0 F-box-like UBM PF14377.6 KXL50769.1 - 0.25 10.9 4.5 1.7 8.2 0.5 2.6 2 0 0 2 2 2 0 Ubiquitin binding region Sugar_tr PF00083.24 KXL50770.1 - 8e-118 394.2 23.8 9.1e-118 394.0 23.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL50770.1 - 5e-24 84.9 35.4 6e-16 58.3 13.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pep3_Vps18 PF05131.14 KXL50771.1 - 6.2e-45 152.7 0.3 1.9e-44 151.1 0.0 2.0 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 KXL50771.1 - 7.5e-12 45.3 9.6 4.4e-11 42.8 1.3 3.3 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_5 PF14634.6 KXL50771.1 - 0.0015 18.5 0.3 0.003 17.5 0.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KXL50771.1 - 0.006 16.2 0.3 0.013 15.1 0.3 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Vps39_2 PF10367.9 KXL50771.1 - 0.0062 17.0 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_11 PF17123.5 KXL50771.1 - 0.0078 15.9 2.2 0.02 14.6 2.2 1.7 1 0 0 1 1 1 1 RING-like zinc finger Nup54_57_C PF18570.1 KXL50771.1 - 0.052 13.1 0.3 0.45 10.1 0.0 2.4 2 0 0 2 2 2 0 NUP57/Nup54 C-terminal domain zf-C3H2C3 PF17122.5 KXL50771.1 - 0.089 12.8 0.3 0.17 12.0 0.3 1.5 1 0 0 1 1 1 0 Zinc-finger zf-RING_UBOX PF13445.6 KXL50771.1 - 0.095 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 KXL50771.1 - 0.12 12.7 0.6 0.31 11.4 0.6 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KXL50771.1 - 0.19 11.6 2.5 0.44 10.4 2.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXL50771.1 - 0.34 11.3 1.5 0.88 10.0 1.5 1.7 1 0 0 1 1 1 0 Ring finger domain Cation_efflux PF01545.21 KXL50772.1 - 5.6e-21 75.2 16.2 7.1e-21 74.8 16.2 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KXL50772.1 - 2.2e-06 27.7 0.0 4.7e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter SNF2_N PF00176.23 KXL50773.1 - 3.6e-52 177.2 0.8 9.8e-51 172.5 0.1 2.7 2 1 1 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXL50773.1 - 4.1e-18 65.7 0.0 3.4e-16 59.6 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 KXL50773.1 - 1.4e-07 31.2 6.7 1.4e-07 31.2 6.7 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KXL50773.1 - 2.1e-07 31.1 0.0 8.6e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_34 PF13872.6 KXL50773.1 - 3.4e-05 22.9 0.3 7.5e-05 21.8 0.0 1.6 2 0 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 DRAT PF07357.11 KXL50773.1 - 7.2e-05 22.1 0.1 0.00054 19.2 0.0 2.1 2 0 0 2 2 2 1 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) zf-C3HC4_2 PF13923.6 KXL50773.1 - 0.00016 21.4 5.2 0.00016 21.4 5.2 2.4 2 1 1 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXL50773.1 - 0.0003 20.6 6.1 0.0003 20.6 6.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 KXL50773.1 - 0.00068 19.4 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_2 PF13639.6 KXL50773.1 - 0.00096 19.4 6.6 0.00096 19.4 6.6 2.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KXL50773.1 - 0.0074 16.3 1.6 0.0074 16.3 1.6 2.1 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXL50773.1 - 0.0075 16.2 7.0 0.0075 16.2 7.0 2.4 2 0 0 2 2 1 1 zinc-RING finger domain ERCC3_RAD25_C PF16203.5 KXL50773.1 - 0.037 13.2 0.0 0.087 12.0 0.0 1.6 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase BNIP2 PF12496.8 KXL50773.1 - 0.11 13.0 3.2 0.22 12.0 1.5 2.2 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 zf-UDP PF14569.6 KXL50773.1 - 0.13 12.4 4.4 0.73 10.0 4.6 2.2 2 0 0 2 2 1 0 Zinc-binding RING-finger Zn_Tnp_IS91 PF14319.6 KXL50773.1 - 1.3 9.1 12.2 0.37 10.9 4.4 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain Prok-RING_4 PF14447.6 KXL50773.1 - 5.1 7.1 13.0 0.15 12.0 6.5 1.9 2 0 0 2 2 1 0 Prokaryotic RING finger family 4 FAD_binding_4 PF01565.23 KXL50774.1 - 4.2e-21 75.1 0.2 1e-20 73.9 0.2 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXL50774.1 - 6.9e-05 22.9 1.9 0.00015 21.8 0.0 2.5 2 0 0 2 2 2 1 Berberine and berberine like YiaAB PF05360.14 KXL50775.1 - 0.24 11.6 0.1 0.24 11.6 0.1 3.4 4 0 0 4 4 4 0 yiaA/B two helix domain THOC2_N PF16134.5 KXL50776.1 - 4.7e-202 673.0 0.1 8.7e-202 672.1 0.1 1.5 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 KXL50776.1 - 3.7e-78 262.8 0.5 7.6e-78 261.7 0.5 1.6 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 KXL50776.1 - 4.1e-28 97.3 0.0 1.1e-27 95.9 0.0 1.8 1 0 0 1 1 1 1 Transcription- and export-related complex subunit PAM2 PF07145.15 KXL50776.1 - 0.081 12.6 0.2 0.2 11.4 0.2 1.6 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Sugar_tr PF00083.24 KXL50777.1 - 6e-107 358.3 21.1 7.3e-107 358.0 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL50777.1 - 6.1e-20 71.4 35.3 4.7e-14 52.1 11.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXL50777.1 - 1.9e-05 23.4 22.5 0.00058 18.5 3.6 3.2 2 2 1 3 3 3 2 MFS/sugar transport protein Peroxin-3 PF04882.12 KXL50778.1 - 6.4e-157 523.3 0.2 7.7e-157 523.1 0.2 1.1 1 0 0 1 1 1 1 Peroxin-3 Glyco_hydro_64 PF16483.5 KXL50779.1 - 7.4e-119 397.3 2.8 8.6e-119 397.1 2.8 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase DnaJ_C PF01556.18 KXL50781.1 - 4.2e-36 124.2 0.9 5.9e-36 123.8 0.9 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KXL50781.1 - 2.1e-24 85.4 1.5 4.3e-24 84.4 1.5 1.5 1 0 0 1 1 1 1 DnaJ domain RAI1 PF08652.11 KXL50782.1 - 1.1e-23 83.2 0.0 2.3e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease DUF922 PF06037.11 KXL50782.1 - 0.19 11.5 0.2 0.5 10.2 0.0 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF922) Peptidase_C78 PF07910.13 KXL50784.1 - 5.3e-46 156.8 0.0 6.4e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C78 Creatinase_N_2 PF16189.5 KXL50785.1 - 1.4e-53 181.2 0.1 3.4e-52 176.8 0.0 2.7 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KXL50785.1 - 3.3e-46 157.6 0.0 5.3e-46 157.0 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KXL50785.1 - 8.2e-26 89.9 0.1 2.3e-25 88.4 0.1 1.8 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KXL50785.1 - 1.9e-24 86.8 0.0 3.3e-18 66.6 0.0 2.9 3 0 0 3 3 3 2 Creatinase/Prolidase N-terminal domain ArgJ PF01960.18 KXL50786.1 - 1.4e-141 471.6 1.6 1.7e-141 471.4 1.6 1.1 1 0 0 1 1 1 1 ArgJ family MFS_1 PF07690.16 KXL50787.1 - 1e-40 139.8 25.8 3.2e-38 131.6 16.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL50787.1 - 2.8e-08 33.1 4.2 2.8e-08 33.1 4.2 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXL50787.1 - 0.00055 18.5 2.9 0.00097 17.7 2.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KXL50787.1 - 0.002 17.0 7.6 0.11 11.4 6.9 2.9 1 1 0 1 1 1 1 MFS_1 like family LacY_symp PF01306.19 KXL50787.1 - 0.033 13.0 7.0 0.02 13.7 4.1 1.9 1 1 1 2 2 2 0 LacY proton/sugar symporter DUF443 PF04276.12 KXL50787.1 - 0.85 9.4 3.8 0.17 11.7 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Glyco_hydro_43 PF04616.14 KXL50788.1 - 2.8e-20 72.8 0.0 3.5e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 ABC1 PF03109.16 KXL50791.1 - 2.4e-35 121.3 0.0 3.8e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 KXL50791.1 - 0.18 11.1 0.0 3.2 7.0 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Gly_transf_sug PF04488.15 KXL50792.1 - 3.6e-19 69.2 0.0 5.5e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif HemY_N PF07219.13 KXL50792.1 - 0.11 12.7 0.5 0.11 12.7 0.5 2.2 2 0 0 2 2 2 0 HemY protein N-terminus Ribosomal_L39 PF00832.20 KXL50793.1 - 1.9e-21 75.4 9.4 2.1e-21 75.2 9.4 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein CN_hydrolase PF00795.22 KXL50794.1 - 3.4e-14 52.8 0.0 6.9e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PIG-P PF08510.12 KXL50795.1 - 4e-53 178.4 0.4 5.6e-53 178.0 0.4 1.2 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 KXL50795.1 - 0.025 14.9 11.9 0.042 14.1 11.9 1.2 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) US6 PF17616.2 KXL50797.1 - 0.079 12.9 0.0 0.087 12.8 0.0 1.1 1 0 0 1 1 1 0 Viral unique short region 6 Dpy19 PF10034.9 KXL50797.1 - 0.12 10.6 0.0 0.14 10.3 0.0 1.0 1 0 0 1 1 1 0 Q-cell neuroblast polarisation Ribosomal_L23eN PF03939.13 KXL50798.1 - 2e-24 85.6 10.9 2e-24 85.6 10.9 1.8 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 KXL50798.1 - 4.2e-16 59.1 0.2 4.2e-16 59.1 0.2 1.7 2 1 0 2 2 2 1 Ribosomal protein L23 DUF3326 PF11805.8 KXL50798.1 - 0.051 12.4 0.1 0.059 12.2 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3326) zf-Tim10_DDP PF02953.15 KXL50799.1 - 6.5e-24 83.4 2.4 1.1e-23 82.7 2.4 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger PAZ_siRNAbind PF12212.8 KXL50799.1 - 0.0042 16.9 0.1 0.0047 16.8 0.1 1.1 1 0 0 1 1 1 1 PAZ domain NAP PF00956.18 KXL50800.1 - 2.8e-96 321.9 12.9 2.8e-96 321.9 12.9 1.8 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) UFD1 PF03152.14 KXL50801.1 - 3.2e-74 248.1 0.0 4.1e-74 247.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Bmt2 PF11968.8 KXL50802.1 - 1e-81 274.0 0.0 1.3e-81 273.6 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 KXL50802.1 - 0.053 13.4 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF89 PF01937.19 KXL50803.1 - 5.8e-131 436.6 0.0 6.6e-131 436.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 MARVEL PF01284.23 KXL50804.1 - 0.00027 21.0 8.6 0.00039 20.5 8.6 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF3325 PF11804.8 KXL50804.1 - 0.82 9.9 5.3 9.4 6.5 1.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3325) TPR_2 PF07719.17 KXL50805.1 - 7.3e-07 28.8 1.1 0.00029 20.7 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXL50805.1 - 8.3e-06 25.4 0.0 0.0091 15.8 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXL50805.1 - 0.00016 21.9 0.2 0.026 14.8 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXL50805.1 - 0.017 15.3 0.1 3 8.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXL50805.1 - 0.031 14.9 1.3 0.64 10.7 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXL50805.1 - 0.11 12.5 0.4 2.4 8.4 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXL50805.1 - 0.13 13.1 1.8 8.6 7.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXL50805.1 - 0.29 11.0 2.0 2.5 8.1 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat RR_TM4-6 PF06459.12 KXL50806.1 - 0.66 9.8 5.0 0.7 9.7 5.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CorA PF01544.18 KXL50809.1 - 2.5e-42 145.2 0.0 3e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Acyl_transf_3 PF01757.22 KXL50810.1 - 6.6e-05 22.1 39.8 0.00012 21.2 39.8 1.4 1 1 0 1 1 1 1 Acyltransferase family Phage_holin_3_6 PF07332.11 KXL50811.1 - 1.2 9.2 7.9 6 7.0 0.0 2.8 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Glyco_hydro_16 PF00722.21 KXL50812.1 - 1.9e-05 24.2 1.8 3.3e-05 23.4 1.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Acyl_transf_3 PF01757.22 KXL50812.1 - 0.019 14.1 45.5 0.041 13.0 45.5 1.6 1 1 0 1 1 1 0 Acyltransferase family SOR_SNZ PF01680.17 KXL50813.1 - 8e-109 362.2 6.7 1.1e-108 361.8 6.7 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 KXL50813.1 - 1.8e-07 30.7 11.7 1.6e-06 27.6 0.6 2.7 1 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 KXL50813.1 - 7.7e-05 21.9 0.3 0.035 13.2 0.0 2.4 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.14 KXL50813.1 - 0.00017 20.8 0.7 0.0028 16.9 0.0 2.5 2 2 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 KXL50813.1 - 0.00095 18.7 0.6 0.0089 15.5 0.1 2.3 2 0 0 2 2 2 1 Histidine biosynthesis protein TetR_C_27 PF17935.1 KXL50813.1 - 0.0054 16.8 0.0 0.017 15.2 0.0 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain IGPS PF00218.21 KXL50813.1 - 0.0087 15.3 0.3 0.19 10.8 0.0 2.5 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase NMO PF03060.15 KXL50813.1 - 0.034 13.5 6.4 0.041 13.3 0.2 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase zf_UBZ PF18439.1 KXL50814.1 - 0.11 12.0 2.0 0.2 11.3 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger FeS PF04060.13 KXL50814.1 - 0.16 11.7 0.3 0.16 11.7 0.3 1.8 2 0 0 2 2 2 0 Putative Fe-S cluster zf-Di19 PF05605.12 KXL50814.1 - 0.39 11.0 5.8 0.1 12.9 1.6 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KXL50814.1 - 5.4 8.1 6.2 3.1 8.9 1.8 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Myb_DNA-binding PF00249.31 KXL50815.1 - 7.6e-16 58.0 0.0 5.5e-07 29.7 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KXL50815.1 - 9.7e-05 22.2 0.2 9.7e-05 22.2 0.2 2.4 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 KXL50815.1 - 0.00088 19.5 0.1 0.41 10.9 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain DS PF01916.17 KXL50819.1 - 3.6e-134 446.5 0.0 4.1e-134 446.3 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Carbam_trans_N PF02543.15 KXL50819.1 - 0.13 11.9 0.2 0.2 11.3 0.2 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus zf-C3HC4_3 PF13920.6 KXL50820.1 - 4.1e-12 45.7 8.4 7.8e-12 44.9 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UCH PF00443.29 KXL50820.1 - 1.3e-06 28.2 0.0 1.9e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Prok-RING_4 PF14447.6 KXL50820.1 - 4.7e-06 26.4 7.3 9.2e-06 25.4 7.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 MORN PF02493.20 KXL50820.1 - 3.2e-05 23.5 21.6 0.0021 17.8 1.2 4.9 4 0 0 4 4 4 3 MORN repeat zf-RING_2 PF13639.6 KXL50820.1 - 0.0014 18.9 8.0 0.003 17.9 8.0 1.6 1 0 0 1 1 1 1 Ring finger domain Transformer PF06495.11 KXL50820.1 - 0.0044 17.1 8.8 0.0088 16.2 8.8 1.4 1 0 0 1 1 1 1 Fruit fly transformer protein zf-RING_5 PF14634.6 KXL50820.1 - 0.19 11.7 8.8 0.4 10.7 8.8 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXL50820.1 - 0.28 11.2 3.3 1.4 9.0 3.4 2.2 1 1 1 2 2 2 0 RING-type zinc-finger Corona_nucleoca PF00937.18 KXL50820.1 - 5.3 6.0 10.5 8.8 5.3 10.5 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein GYF PF02213.16 KXL50821.1 - 5e-13 48.5 0.9 1.3e-12 47.1 0.9 1.8 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 KXL50821.1 - 0.011 15.6 0.0 0.026 14.3 0.0 1.7 1 0 0 1 1 1 0 GYF domain 2 TORC_N PF12884.7 KXL50821.1 - 0.08 13.7 0.3 0.33 11.8 0.3 2.2 1 0 0 1 1 1 0 Transducer of regulated CREB activity, N terminus VHP PF02209.19 KXL50821.1 - 0.96 9.6 4.4 2.4 8.3 4.4 1.7 1 0 0 1 1 1 0 Villin headpiece domain Bac_rhamnosid6H PF17389.2 KXL50822.1 - 1.1e-08 34.7 1.0 3.3e-07 29.9 1.0 2.2 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 KXL50822.1 - 3.3e-07 30.0 0.0 6.9e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Trehalase PF01204.18 KXL50822.1 - 0.0094 14.8 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Trehalase Bac_rhamnosid PF05592.11 KXL50822.1 - 0.043 13.8 0.0 0.083 12.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain Sec1 PF00995.23 KXL50823.1 - 6.4e-133 445.0 0.0 7.4e-133 444.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family VacA2 PF03077.14 KXL50823.1 - 0.11 12.3 0.3 0.39 10.6 0.3 1.9 1 0 0 1 1 1 0 Putative vacuolating cytotoxin Abhydrolase_4 PF08386.10 KXL50823.1 - 0.12 12.5 0.1 0.45 10.7 0.0 2.0 2 0 0 2 2 2 0 TAP-like protein TPP_enzyme_N PF02776.18 KXL50824.1 - 9e-43 145.8 0.5 3.8e-38 130.8 0.1 2.2 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KXL50824.1 - 5.3e-25 88.0 0.0 1.5e-24 86.5 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXL50824.1 - 1.6e-18 66.7 0.0 3.8e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain E1_dh PF00676.20 KXL50824.1 - 0.003 16.6 0.2 0.02 13.9 0.2 2.0 1 1 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KXL50824.1 - 0.065 12.4 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase PhyH PF05721.13 KXL50825.1 - 8.4e-09 36.0 0.1 8.1e-08 32.8 0.1 2.2 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF4203 PF13886.6 KXL50827.1 - 7.7e-52 175.9 28.2 9.8e-52 175.5 28.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Plasmodium_Vir PF05795.11 KXL50827.1 - 0.053 12.9 2.8 5.2 6.4 0.0 2.9 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DUF5408 PF17402.2 KXL50827.1 - 0.12 12.3 1.5 7.3 6.6 0.1 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5408) DUF2423 PF10338.9 KXL50829.1 - 3e-20 72.2 4.4 3.9e-20 71.8 4.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) DivIC PF04977.15 KXL50829.1 - 0.018 14.8 1.3 0.039 13.7 0.2 1.8 2 0 0 2 2 2 0 Septum formation initiator PINIT PF14324.6 KXL50830.1 - 7.2e-37 127.0 0.5 1.1e-36 126.3 0.5 1.3 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 KXL50830.1 - 2.9e-19 68.6 1.9 4.7e-19 67.9 1.9 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KXL50830.1 - 9.6e-08 31.7 0.5 2e-07 30.7 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 KXL50830.1 - 4.5e-07 29.5 0.5 8.1e-07 28.7 0.5 1.4 1 0 0 1 1 1 1 SAP domain zf-Sec23_Sec24 PF04810.15 KXL50830.1 - 0.17 11.9 2.2 0.47 10.5 2.2 1.7 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger FA_hydroxylase PF04116.13 KXL50832.1 - 2.1e-24 86.4 16.6 2.1e-24 86.4 16.6 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily PEP_mutase PF13714.6 KXL50833.1 - 1.1e-30 106.8 0.6 1.3e-30 106.7 0.6 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase AP_endonuc_2 PF01261.24 KXL50833.1 - 0.038 13.4 0.1 0.074 12.5 0.1 1.3 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel AsnC_trans_reg PF01037.21 KXL50833.1 - 0.077 13.0 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Lrp/AsnC ligand binding domain PH PF00169.29 KXL50834.1 - 0.00041 20.8 0.3 0.0054 17.2 0.0 2.8 3 1 0 3 3 3 1 PH domain PNRC PF15365.6 KXL50835.1 - 4.8e-09 35.8 6.9 4.8e-09 35.8 6.9 2.8 2 0 0 2 2 2 1 Proline-rich nuclear receptor coactivator motif zf-rbx1 PF12678.7 KXL50836.1 - 4.9e-25 87.6 12.9 6.5e-25 87.2 12.9 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KXL50836.1 - 3.5e-17 62.2 10.1 4.5e-17 61.9 10.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KXL50836.1 - 3e-06 27.5 14.7 0.00011 22.5 14.7 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXL50836.1 - 7.9e-05 22.4 3.5 7.9e-05 22.4 3.5 2.4 1 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXL50836.1 - 0.0017 18.2 11.6 0.022 14.6 11.6 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXL50836.1 - 0.23 11.2 15.3 19 5.1 15.3 2.4 1 1 0 1 1 1 0 RING-like zinc finger zf-C3HC4_3 PF13920.6 KXL50836.1 - 0.36 10.7 10.9 1.1 9.2 4.4 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXL50836.1 - 0.54 10.3 7.9 1.9 8.6 7.9 1.9 1 1 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.8 KXL50836.1 - 0.59 10.3 9.3 2.9 8.1 9.5 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KXL50836.1 - 0.73 9.5 14.7 0.17 11.5 5.0 2.2 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type SPC12 PF06645.13 KXL50837.1 - 4.7e-29 100.3 0.4 5.5e-29 100.1 0.4 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF3040 PF11239.8 KXL50837.1 - 0.014 15.6 0.4 0.018 15.3 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) m04gp34like PF12216.8 KXL50841.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Immune evasion protein Herpes_LMP2 PF07415.11 KXL50841.1 - 0.76 8.5 4.3 1.3 7.7 4.3 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein F-box PF00646.33 KXL50842.1 - 1.2e-06 28.2 0.3 2.9e-06 27.0 0.3 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXL50842.1 - 1.9e-05 24.4 0.0 4.1e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 F-box-like DDE_Tnp_4 PF13359.6 KXL50842.1 - 0.015 15.0 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 DDE superfamily endonuclease SAP130_C PF16014.5 KXL50843.1 - 0.018 14.1 0.2 0.024 13.8 0.2 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus SIR2 PF02146.17 KXL50845.1 - 2.1e-33 115.7 0.0 3e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF2529 PF10740.9 KXL50845.1 - 0.18 11.4 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2529) Cas6 PF09559.10 KXL50847.1 - 0.065 13.2 0.0 0.066 13.2 0.0 1.1 1 0 0 1 1 1 0 Cas6 Crispr GST_C_6 PF17171.4 KXL50847.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Cytochrom_B561 PF03188.16 KXL50848.1 - 4.3e-05 23.7 4.6 6.7e-05 23.0 4.6 1.2 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 ATP-synt_DE_N PF02823.16 KXL50849.1 - 1.8e-16 59.8 0.0 2.9e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Fungal_trans_2 PF11951.8 KXL50850.1 - 6.4e-10 38.4 0.0 1.1e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL50850.1 - 5.6e-07 29.6 9.6 9.6e-07 28.8 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_7 PF13176.6 KXL50850.1 - 0.14 12.3 0.1 0.35 11.0 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat adh_short PF00106.25 KXL50851.1 - 1e-21 77.3 0.7 1.8e-21 76.5 0.7 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL50851.1 - 3.6e-13 49.6 4.1 9.6e-13 48.2 4.1 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL50851.1 - 1.7e-06 28.1 4.1 0.00026 21.0 4.1 2.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL50851.1 - 6.5e-06 25.8 0.5 5.5e-05 22.7 0.5 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family FtsJ PF01728.19 KXL50851.1 - 0.0002 21.5 0.0 0.00032 20.9 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase RmlD_sub_bind PF04321.17 KXL50851.1 - 0.0023 17.1 0.1 0.003 16.7 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain PIN_4 PF13638.6 KXL50852.1 - 0.00075 19.8 0.0 0.00089 19.6 0.0 1.1 1 0 0 1 1 1 1 PIN domain FGGY_C PF02782.16 KXL50853.1 - 1.4e-25 90.2 0.0 2e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KXL50853.1 - 2.7e-13 50.1 0.0 2.3e-08 33.9 0.0 2.6 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Thioredoxin PF00085.20 KXL50854.1 - 2.1e-20 72.6 0.0 2.3e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 KXL50854.1 - 5.2e-05 23.0 0.0 5.7e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KXL50854.1 - 0.0058 17.1 0.1 0.024 15.1 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KXL50854.1 - 0.021 15.1 0.0 0.096 13.0 0.0 1.9 1 1 1 2 2 2 0 Thioredoxin-like PCYCGC PF13798.6 KXL50854.1 - 0.022 14.6 0.3 0.039 13.8 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function with PCYCGC motif AhpC-TSA PF00578.21 KXL50854.1 - 0.029 14.3 0.0 0.039 13.9 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family OSR1_C PF12202.8 KXL50854.1 - 0.057 13.7 0.0 0.093 13.0 0.0 1.4 1 0 0 1 1 1 0 Oxidative-stress-responsive kinase 1 C-terminal domain Methyltransf_2 PF00891.18 KXL50854.1 - 0.081 12.2 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase domain HyaE PF07449.11 KXL50854.1 - 0.12 12.3 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE PHB_acc_N PF07879.11 KXL50854.1 - 0.17 12.0 1.2 13 6.0 0.1 2.4 2 0 0 2 2 2 0 PHB/PHA accumulation regulator DNA-binding domain FKBP_C PF00254.28 KXL50855.1 - 1.9e-34 117.9 0.0 2.3e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Exo_endo_phos PF03372.23 KXL50856.1 - 7.3e-09 35.5 0.0 1.6e-08 34.4 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.32 KXL50856.1 - 0.083 13.8 0.6 1.5 9.8 0.1 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat zf-CHY PF05495.12 KXL50857.1 - 4.5e-12 46.3 20.2 8e-12 45.5 20.2 1.4 1 0 0 1 1 1 1 CHY zinc finger Cys_rich_KTR PF14205.6 KXL50857.1 - 0.46 10.3 7.6 2.7 7.9 3.1 2.5 1 1 1 2 2 2 0 Cysteine-rich KTR C1_4 PF07975.12 KXL50857.1 - 8.5 6.7 17.1 13 6.1 9.6 2.7 1 1 2 3 3 3 0 TFIIH C1-like domain Sdh_cyt PF01127.22 KXL50858.1 - 7.4e-25 87.3 4.8 1e-24 86.9 4.8 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Methyltransf_16 PF10294.9 KXL50859.1 - 3.6e-15 56.1 0.0 4.7e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KXL50859.1 - 0.00068 19.5 0.0 0.00091 19.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KXL50859.1 - 0.0038 16.5 0.0 0.0058 15.9 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family GidB PF02527.15 KXL50859.1 - 0.014 14.7 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_25 PF13649.6 KXL50859.1 - 0.065 13.9 0.0 0.18 12.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KXL50859.1 - 0.15 11.7 0.0 0.39 10.3 0.0 1.5 1 1 0 1 1 1 0 Conserved hypothetical protein 95 DEAD PF00270.29 KXL50860.1 - 6.9e-33 113.9 0.5 3.1e-32 111.7 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXL50860.1 - 4.4e-25 88.2 0.2 1.6e-24 86.4 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL50860.1 - 0.00062 19.8 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KXL50860.1 - 0.0095 15.7 0.1 0.02 14.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain tRNA-synt_1b PF00579.25 KXL50860.1 - 0.046 13.0 0.0 0.087 12.1 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) FCH PF00611.23 KXL50861.1 - 3.4e-27 94.5 3.1 1.3e-26 92.7 0.2 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 KXL50861.1 - 1.3e-15 57.0 0.3 1e-06 28.5 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KXL50861.1 - 2.6e-14 52.6 0.0 5.1e-07 29.2 0.0 2.4 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.22 KXL50861.1 - 4.7e-13 48.8 3.3 7.6e-13 48.1 3.3 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_2 PF07653.17 KXL50861.1 - 0.00056 19.5 0.1 0.28 10.9 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_10 PF17902.1 KXL50861.1 - 0.046 13.8 0.0 4.6 7.4 0.0 2.8 2 0 0 2 2 2 0 SH3 domain C1_2 PF03107.16 KXL50861.1 - 0.068 13.5 4.6 0.15 12.4 4.6 1.6 1 0 0 1 1 1 0 C1 domain FapA PF03961.13 KXL50861.1 - 0.28 9.8 4.1 0.59 8.7 4.1 1.6 1 0 0 1 1 1 0 Flagellar Assembly Protein A PHD PF00628.29 KXL50861.1 - 1.1 9.2 6.4 2.3 8.2 6.4 1.5 1 0 0 1 1 1 0 PHD-finger FAM184 PF15665.5 KXL50861.1 - 1.9 8.3 21.6 0.05 13.4 12.5 2.7 2 1 0 2 2 2 0 Family with sequence similarity 184, A and B GFA PF04828.14 KXL50862.1 - 2.9e-10 40.4 1.0 2.9e-10 40.4 1.0 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme BRD4_CDT PF17105.5 KXL50862.1 - 0.072 12.7 0.5 0.13 11.9 0.5 1.4 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 Copper-fist PF00649.18 KXL50864.1 - 2.8e-05 23.5 5.0 2.8e-05 23.5 5.0 1.9 2 0 0 2 2 2 1 Copper fist DNA binding domain LRR_8 PF13855.6 KXL50866.1 - 2.5e-11 43.1 3.4 3.3e-11 42.8 1.6 2.2 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 KXL50866.1 - 1.5e-06 28.5 12.1 3.7e-05 24.0 1.5 3.4 3 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXL50866.1 - 0.061 13.9 5.0 7.8 7.5 0.3 4.3 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 KXL50866.1 - 1.8 8.8 5.1 13 6.1 0.0 4.1 4 0 0 4 4 4 0 Leucine Rich repeat ATG16 PF08614.11 KXL50869.1 - 0.0055 16.9 34.3 0.057 13.6 25.2 2.5 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) Vps5 PF09325.10 KXL50869.1 - 0.0099 15.4 23.2 0.01 15.4 3.7 3.0 1 1 2 3 3 3 2 Vps5 C terminal like Spc7 PF08317.11 KXL50869.1 - 0.015 14.2 36.1 0.014 14.3 20.6 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KXL50869.1 - 0.035 14.2 39.3 0.036 14.1 21.2 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.8 KXL50869.1 - 0.48 10.4 39.0 0.22 11.6 4.4 4.3 2 1 2 5 5 5 0 TATA element modulatory factor 1 DNA binding MCPsignal PF00015.21 KXL50869.1 - 1.1 9.1 14.0 1.4 8.7 8.7 2.6 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain APG6_N PF17675.1 KXL50869.1 - 1.6 9.3 36.5 0.16 12.5 27.0 3.0 1 1 1 2 2 2 0 Apg6 coiled-coil region Sod_Fe_N PF00081.22 KXL50869.1 - 2.3 8.7 9.2 2.8 8.5 0.5 3.5 2 1 1 3 3 3 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Atg14 PF10186.9 KXL50869.1 - 2.6 7.1 31.9 0.45 9.6 22.9 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Tropomyosin_1 PF12718.7 KXL50869.1 - 2.9 8.0 37.3 0.56 10.4 13.5 2.6 1 1 1 2 2 2 0 Tropomyosin like DUF745 PF05335.13 KXL50869.1 - 3.2 7.4 27.3 3 7.5 17.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF745) CENP-F_leu_zip PF10473.9 KXL50869.1 - 4 7.5 34.3 9.9 6.2 16.1 2.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 KXL50869.1 - 4.9 6.4 23.3 1.1 8.6 9.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ERM PF00769.19 KXL50869.1 - 5.1 6.8 39.3 0.93 9.3 33.8 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family SlyX PF04102.12 KXL50869.1 - 6.1 7.5 26.4 0.21 12.2 4.8 4.5 2 1 2 4 4 4 0 SlyX PKcGMP_CC PF16808.5 KXL50869.1 - 6.4 6.7 25.9 8 6.4 7.0 4.0 2 1 1 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase GAS PF13851.6 KXL50869.1 - 7.4 5.9 38.4 1.3 8.3 24.7 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Bacillus_HBL PF05791.11 KXL50869.1 - 8.7 6.1 21.4 0.14 12.0 8.8 2.6 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF5082 PF16888.5 KXL50869.1 - 9.8 6.5 29.6 1.1 9.6 9.3 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) GMC_oxred_N PF00732.19 KXL50871.1 - 4.2e-08 32.9 0.0 4.5e-08 32.8 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KXL50871.1 - 4.8e-05 23.5 0.3 7.1e-05 23.0 0.3 1.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXL50871.1 - 0.00014 21.1 0.2 0.00017 20.8 0.2 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KXL50871.1 - 0.00072 18.9 0.1 0.00083 18.7 0.1 1.1 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KXL50871.1 - 0.0015 17.7 0.1 0.0016 17.6 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXL50871.1 - 0.0023 17.2 0.1 0.0026 17.1 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXL50871.1 - 0.011 15.3 0.8 0.013 15.1 0.8 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXL50871.1 - 0.015 14.5 0.2 0.017 14.4 0.2 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXL50871.1 - 0.015 14.0 0.1 0.018 13.7 0.1 1.0 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 KXL50871.1 - 0.028 13.3 0.2 0.032 13.1 0.2 1.1 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 KXL50871.1 - 0.042 13.9 0.3 0.054 13.5 0.3 1.2 1 0 0 1 1 1 0 FAD-NAD(P)-binding But2 PF09792.9 KXL50872.1 - 1.2e-54 184.6 0.2 1.8e-54 184.0 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Peptidase_M60_C PF18630.1 KXL50872.1 - 0.065 13.4 0.0 1.1 9.4 0.0 2.6 3 0 0 3 3 3 0 Peptidase M60 C-terminal domain HeLo PF14479.6 KXL50873.1 - 8e-44 149.9 0.6 1.4e-43 149.1 0.6 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.25 KXL50873.1 - 0.0011 18.3 0.0 0.01 15.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL50873.1 - 0.011 15.0 0.0 0.025 13.9 0.0 1.7 1 1 0 1 1 1 0 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXL50873.1 - 0.067 12.0 0.0 2.9 6.6 0.0 2.4 3 0 0 3 3 3 0 Fungal protein kinase Ank_2 PF12796.7 KXL50874.1 - 9e-36 122.3 0.8 4.5e-06 27.2 0.1 7.5 4 1 2 7 7 7 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXL50874.1 - 1.3e-25 86.6 12.5 0.0021 18.4 0.0 11.3 13 0 0 13 13 13 6 Ankyrin repeat Pkinase PF00069.25 KXL50874.1 - 5.5e-25 88.2 0.0 9.5e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL50874.1 - 1e-21 77.4 0.0 1.8e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_4 PF13637.6 KXL50874.1 - 3.8e-18 65.6 12.2 0.0008 19.9 0.0 8.5 7 2 3 10 10 10 5 Ankyrin repeats (many copies) Ank PF00023.30 KXL50874.1 - 1.7e-16 59.8 11.6 0.0023 18.3 0.0 9.8 12 0 0 12 12 12 4 Ankyrin repeat Ank_5 PF13857.6 KXL50874.1 - 2.2e-14 53.3 3.0 0.001 19.3 0.0 7.4 6 1 1 7 7 7 2 Ankyrin repeats (many copies) Pkinase_fungal PF17667.1 KXL50874.1 - 2.6e-05 23.2 0.0 4.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Sas10_Utp3 PF04000.15 KXL50875.1 - 6.1e-09 36.4 1.3 1e-08 35.7 0.1 2.0 2 0 0 2 2 2 1 Sas10/Utp3/C1D family DUF1517 PF07466.11 KXL50875.1 - 0.0027 17.9 0.6 0.0027 17.9 0.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1517) E_Pc_C PF06752.12 KXL50876.1 - 1.2 9.2 7.4 1.5 8.9 7.4 1.1 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus ADK PF00406.22 KXL50877.1 - 1.2e-56 191.0 0.0 1.6e-56 190.6 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KXL50877.1 - 7.6e-19 68.5 0.8 1.3e-18 67.7 0.2 1.7 1 1 1 2 2 2 1 AAA domain ADK_lid PF05191.14 KXL50877.1 - 3.7e-17 62.0 0.1 1.5e-16 60.1 0.0 2.1 3 0 0 3 3 3 1 Adenylate kinase, active site lid Trimer_CC PF08954.11 KXL50877.1 - 0.077 12.6 0.5 0.15 11.6 0.5 1.4 1 0 0 1 1 1 0 Trimerisation motif WD40 PF00400.32 KXL50878.1 - 3.2e-36 122.7 8.3 1.1e-07 32.4 0.1 7.0 5 1 1 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXL50878.1 - 1.7e-21 76.3 1.2 2.4e-05 24.5 0.0 5.9 2 1 4 6 6 5 5 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KXL50878.1 - 5.5e-12 45.3 0.9 0.052 13.5 0.0 6.3 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KXL50878.1 - 2.7e-11 43.0 0.6 0.0055 15.7 0.1 5.0 1 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 KXL50878.1 - 1.1e-09 38.4 0.0 2.5e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain HET PF06985.11 KXL50878.1 - 2.5e-05 24.7 1.0 0.12 12.8 0.0 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) AAA_16 PF13191.6 KXL50878.1 - 0.00014 22.3 1.4 0.0022 18.4 0.6 2.8 2 1 0 2 2 1 1 AAA ATPase domain Proteasome_A_N PF10584.9 KXL50878.1 - 0.0041 16.8 0.8 31 4.4 0.0 4.7 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature APS_kinase PF01583.20 KXL50878.1 - 0.023 14.6 0.2 0.058 13.3 0.1 1.7 2 0 0 2 2 1 0 Adenylylsulphate kinase AAA_18 PF13238.6 KXL50878.1 - 0.025 15.1 0.0 0.17 12.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain VID27 PF08553.10 KXL50878.1 - 0.055 12.5 0.3 1.2 8.1 0.0 2.4 1 1 2 3 3 3 0 VID27 C-terminal WD40-like domain SurE PF01975.17 KXL50878.1 - 0.07 12.9 0.2 5.8 6.6 0.0 3.5 3 1 1 4 4 4 0 Survival protein SurE DUF4596 PF15363.6 KXL50878.1 - 0.093 13.0 0.2 1.6 9.0 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) AAA_30 PF13604.6 KXL50878.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KXL50878.1 - 0.11 12.9 0.0 0.29 11.5 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF3435 PF11917.8 KXL50879.1 - 6.3e-35 120.9 0.1 1.2e-34 120.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) SUIM_assoc PF16619.5 KXL50879.1 - 1.5 8.9 4.5 4.9 7.3 0.0 3.5 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 zf-met PF12874.7 KXL50879.1 - 2.4 8.7 9.9 1.3 9.5 1.5 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KXL50879.1 - 3.2 8.3 30.8 3.7 8.2 0.6 6.6 6 0 0 6 6 6 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KXL50879.1 - 9.8 6.6 10.4 0.28 11.5 1.4 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding MFS_1 PF07690.16 KXL50881.1 - 1.3e-10 40.8 45.9 4.7e-10 38.9 46.0 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL50881.1 - 0.0004 19.4 11.0 0.0004 19.4 11.0 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter FAD_binding_3 PF01494.19 KXL50882.1 - 3.6e-25 89.0 0.0 5.2e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KXL50882.1 - 0.00014 21.3 0.0 0.12 11.6 0.0 2.5 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase SE PF08491.10 KXL50882.1 - 0.0003 19.9 0.0 0.024 13.7 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.6 KXL50882.1 - 0.00044 20.4 0.1 0.0012 19.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXL50882.1 - 0.00063 19.4 0.2 0.0019 17.8 0.0 1.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXL50882.1 - 0.0021 17.3 0.0 0.093 12.0 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXL50882.1 - 0.0032 18.0 0.1 0.019 15.5 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXL50882.1 - 0.013 14.7 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXL50882.1 - 0.027 13.6 2.1 0.22 10.6 0.0 2.5 3 0 0 3 3 3 0 FAD binding domain HTH_psq PF05225.16 KXL50883.1 - 1.3e-06 28.0 0.1 1.7e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.6 KXL50883.1 - 0.064 13.4 0.1 0.093 12.9 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Ribosomal_L7Ae PF01248.26 KXL50884.1 - 6.2e-27 93.2 0.1 7.2e-27 93.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KXL50884.1 - 1.8e-05 24.9 0.1 1.9e-05 24.7 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 KXL50884.1 - 0.00023 21.0 0.0 0.00032 20.5 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain Toprim_C_rpt PF13368.6 KXL50884.1 - 0.16 11.9 0.1 22 5.1 0.0 2.2 2 0 0 2 2 2 0 Topoisomerase C-terminal repeat Tom22 PF04281.13 KXL50885.1 - 1.4e-29 102.7 9.2 1.6e-28 99.3 0.5 2.0 1 1 1 2 2 2 2 Mitochondrial import receptor subunit Tom22 Importin_rep_6 PF18829.1 KXL50885.1 - 0.0061 16.7 0.7 0.0081 16.3 0.7 1.3 1 0 0 1 1 1 1 Importin repeat 6 CRAL_TRIO PF00650.20 KXL50888.1 - 2.6e-37 128.0 0.0 3.4e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXL50888.1 - 1.3e-16 60.5 0.3 3.8e-16 59.0 0.3 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KXL50888.1 - 0.004 17.3 0.0 0.0073 16.5 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Fungal_trans PF04082.18 KXL50889.1 - 6.2e-30 104.1 0.0 1.5e-29 102.8 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL50889.1 - 4.4e-09 36.3 9.7 7.4e-09 35.6 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GILT PF03227.16 KXL50890.1 - 7.7e-20 71.1 0.2 1.2e-19 70.5 0.2 1.3 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Sugar_tr PF00083.24 KXL50891.1 - 1.2e-92 311.2 25.1 1.5e-92 310.9 25.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL50891.1 - 1e-13 51.0 50.2 1.9e-08 33.7 18.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily NIR_SIR PF01077.22 KXL50892.1 - 4.7e-53 178.9 0.0 3.7e-47 159.8 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 KXL50892.1 - 6.5e-32 109.2 0.0 9.3e-15 54.2 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 KXL50892.1 - 6.2e-28 97.8 0.0 1.3e-27 96.7 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 KXL50892.1 - 1.8e-09 37.7 0.0 1.8e-09 37.7 0.0 2.0 3 0 0 3 3 3 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PFOR_II PF17147.4 KXL50892.1 - 0.011 16.0 0.0 0.03 14.6 0.0 1.7 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II HET PF06985.11 KXL50896.1 - 1.9e-33 115.9 0.7 3.6e-33 115.0 0.7 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aldedh PF00171.22 KXL50899.1 - 5.4e-124 414.2 0.0 6.1e-124 414.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KXL50899.1 - 4.9e-06 25.8 0.0 7.8e-06 25.2 0.0 1.3 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Pyr_redox_2 PF07992.14 KXL50900.1 - 1.7e-37 129.2 0.0 2.3e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXL50900.1 - 1.1e-10 41.8 0.0 2e-08 34.7 0.0 3.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 KXL50900.1 - 1.4e-06 27.5 0.3 3.9e-06 26.0 0.3 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXL50900.1 - 1.3e-05 24.7 0.4 4e-05 23.2 0.4 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KXL50900.1 - 0.00021 21.6 0.0 0.00045 20.6 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KXL50900.1 - 0.0029 17.0 0.6 0.0066 15.9 0.6 1.6 1 0 0 1 1 1 1 EF hand Pyr_redox_3 PF13738.6 KXL50900.1 - 0.2 10.9 0.4 0.76 9.0 0.4 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase LRR_9 PF14580.6 KXL50902.1 - 5.8e-55 185.5 0.1 8.5e-55 184.9 0.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KXL50902.1 - 1.4e-07 31.7 2.5 0.00034 20.9 0.7 3.2 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXL50902.1 - 8.2e-05 22.3 1.7 9.3e-05 22.1 0.1 2.0 2 0 0 2 2 2 1 Leucine rich repeat DIM1 PF02966.16 KXL50903.1 - 2.6e-69 231.1 0.2 3e-69 230.9 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 KXL50903.1 - 0.0019 18.2 0.0 0.0023 17.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KXL50903.1 - 0.048 14.0 0.5 0.091 13.1 0.5 1.4 1 1 0 1 1 1 0 Thioredoxin-like DEAD PF00270.29 KXL50904.1 - 4.6e-48 163.3 0.1 1.1e-47 162.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXL50904.1 - 1.7e-22 79.9 0.0 4.6e-22 78.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 KXL50904.1 - 2e-17 63.2 1.6 4.6e-17 62.0 1.6 1.7 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.15 KXL50904.1 - 9.5e-07 29.0 0.0 2.1e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KXL50904.1 - 0.033 13.4 0.0 0.059 12.6 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase RPA_C PF08784.11 KXL50905.1 - 5.9e-17 62.2 0.2 1.1e-15 58.2 0.0 2.5 3 0 0 3 3 3 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 KXL50905.1 - 2.7e-06 27.3 0.0 5.2e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain CHB_HEX_C PF03174.13 KXL50905.1 - 0.15 12.0 0.3 1.9 8.5 0.0 2.6 3 0 0 3 3 3 0 Chitobiase/beta-hexosaminidase C-terminal domain DUF202 PF02656.15 KXL50906.1 - 6.5e-15 55.3 2.2 4e-14 52.8 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) COX4_pro_2 PF07835.12 KXL50906.1 - 0.081 13.0 0.3 0.081 13.0 0.3 2.4 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV RSN1_7TM PF02714.15 KXL50907.1 - 2.2e-87 292.9 19.0 2.2e-87 292.9 19.0 2.2 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KXL50907.1 - 3.7e-39 134.0 3.6 3.7e-39 134.0 3.6 2.8 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KXL50907.1 - 3.7e-35 121.7 0.0 6e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KXL50907.1 - 7.7e-30 102.9 0.5 1.4e-29 102.0 0.5 1.5 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter DUF3377 PF11857.8 KXL50907.1 - 0.82 9.6 4.6 17 5.4 0.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) RNA_pol PF00940.19 KXL50910.1 - 3.7e-188 625.6 0.0 4.8e-188 625.2 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KXL50910.1 - 7.4e-92 308.3 4.1 7.4e-92 308.3 4.1 2.0 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal FYVE PF01363.21 KXL50911.1 - 0.00039 20.5 34.7 0.27 11.4 10.1 3.3 2 1 1 3 3 3 3 FYVE zinc finger FYVE_2 PF02318.16 KXL50911.1 - 0.045 14.0 0.9 0.045 14.0 0.9 3.5 3 1 0 3 3 3 0 FYVE-type zinc finger Zn_Tnp_IS91 PF14319.6 KXL50911.1 - 1.5 8.9 28.6 0.57 10.3 3.5 3.2 3 0 0 3 3 3 0 Transposase zinc-binding domain GDPD PF03009.17 KXL50912.1 - 3.3e-71 240.1 0.0 1.5e-70 237.9 0.0 2.0 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 KXL50912.1 - 1.7e-43 147.1 0.5 7.8e-19 68.1 0.1 3.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXL50912.1 - 1.8e-29 101.7 0.4 9e-11 42.1 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) SPX PF03105.19 KXL50912.1 - 1.4e-21 77.9 10.3 4.3e-12 46.7 0.0 4.2 3 1 1 5 5 5 3 SPX domain Ank_5 PF13857.6 KXL50912.1 - 2.7e-21 75.4 0.0 2e-07 31.1 0.0 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXL50912.1 - 1.2e-19 68.3 0.7 0.00033 20.9 0.0 7.0 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 KXL50912.1 - 3.5e-19 68.3 1.5 0.0009 19.6 0.0 6.0 5 1 0 5 5 5 4 Ankyrin repeat Citrate_bind PF16114.5 KXL50914.1 - 1.2e-88 295.2 0.0 2.6e-88 294.2 0.0 1.5 2 0 0 2 2 2 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 KXL50914.1 - 1.2e-07 31.5 0.0 1.8e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Reovirus_M2 PF05993.12 KXL50914.1 - 0.037 12.1 0.0 0.054 11.6 0.0 1.1 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) ParE_toxin PF05016.15 KXL50914.1 - 0.11 13.1 0.0 0.23 12.1 0.0 1.5 1 0 0 1 1 1 0 ParE toxin of type II toxin-antitoxin system, parDE Citrate_synt PF00285.21 KXL50915.1 - 1.5e-21 76.9 0.0 7.4e-18 64.7 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 KXL50915.1 - 1.6e-18 67.1 0.0 4e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.19 KXL50915.1 - 5.7e-14 52.2 0.2 1.3e-13 51.1 0.2 1.6 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KXL50915.1 - 1.1e-08 34.9 0.0 3.6e-07 30.0 0.0 2.4 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain MAPEG PF01124.18 KXL50916.1 - 5.4e-14 52.2 0.4 7.1e-14 51.8 0.4 1.2 1 0 0 1 1 1 1 MAPEG family Paired_CXXCH_1 PF09699.10 KXL50916.1 - 0.028 14.1 0.1 0.043 13.6 0.1 1.3 1 0 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) His_Phos_2 PF00328.22 KXL50917.1 - 1.2e-10 41.3 0.0 2.9e-10 40.1 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Phage_Coat_B PF05356.11 KXL50917.1 - 0.029 14.2 0.1 0.098 12.6 0.1 1.9 1 0 0 1 1 1 0 Phage Coat protein B DUF1028 PF06267.12 KXL50917.1 - 0.055 13.3 0.3 0.095 12.5 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF1028) PDGLE PF13190.6 KXL50917.1 - 0.18 11.7 2.4 0.3 11.0 0.3 2.5 3 0 0 3 3 3 0 PDGLE domain LSM PF01423.22 KXL50918.1 - 1.7e-19 69.2 0.0 2e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain Clathrin PF00637.20 KXL50919.1 - 1.4e-20 73.6 3.1 3.1e-19 69.3 1.5 2.5 2 0 0 2 2 2 1 Region in Clathrin and VPS VPS11_C PF12451.8 KXL50919.1 - 5.3e-19 68.2 0.1 1.3e-18 67.0 0.1 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 KXL50919.1 - 1.7e-06 27.9 5.5 4.9e-06 26.5 5.5 1.8 1 1 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 KXL50919.1 - 0.00035 20.3 6.3 0.00066 19.5 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_11 PF13414.6 KXL50919.1 - 0.00065 19.3 0.3 0.0022 17.6 0.3 1.9 1 0 0 1 1 1 1 TPR repeat TPR_14 PF13428.6 KXL50919.1 - 0.0027 18.4 3.0 0.54 11.2 0.0 3.5 3 1 0 3 3 2 1 Tetratricopeptide repeat zf-RING_UBOX PF13445.6 KXL50919.1 - 0.004 17.1 3.4 0.0084 16.1 3.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KXL50919.1 - 0.0042 17.4 5.8 0.0083 16.4 5.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KXL50919.1 - 0.0053 16.7 5.6 0.012 15.5 5.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KXL50919.1 - 0.0072 16.4 1.0 0.016 15.3 1.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_16 PF13432.6 KXL50919.1 - 0.043 14.5 0.9 0.81 10.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-rbx1 PF12678.7 KXL50919.1 - 0.044 14.1 3.7 0.094 13.0 3.7 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain TPR_2 PF07719.17 KXL50919.1 - 0.061 13.5 3.8 0.1 12.8 0.1 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat Tfb5 PF06331.12 KXL50919.1 - 0.078 13.0 0.3 0.52 10.3 0.1 2.4 2 0 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 RPAP3_C PF13877.6 KXL50919.1 - 0.14 12.7 0.1 0.48 11.0 0.1 1.9 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 zf-C3HC4 PF00097.25 KXL50919.1 - 0.17 11.8 5.9 0.33 10.9 5.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_Tnp_IS91 PF14319.6 KXL50919.1 - 0.24 11.5 1.6 0.57 10.3 1.6 1.6 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-C2H2_3 PF13878.6 KXL50919.1 - 0.39 10.6 3.0 0.24 11.3 0.2 2.0 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO TPR_8 PF13181.6 KXL50919.1 - 0.59 10.5 3.7 1.4 9.3 0.2 3.4 4 0 0 4 4 2 0 Tetratricopeptide repeat PHD PF00628.29 KXL50919.1 - 1.1 9.2 4.5 2.7 8.0 4.5 1.7 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.6 KXL50919.1 - 2.1 8.6 5.4 4.3 7.6 5.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING ANAPC3 PF12895.7 KXL50919.1 - 3.3 8.0 5.1 17 5.7 0.2 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DDHD PF02862.17 KXL50920.1 - 3.2e-26 92.9 0.3 1e-16 61.8 0.0 2.8 2 1 1 3 3 3 2 DDHD domain Abhydrolase_6 PF12697.7 KXL50920.1 - 0.037 14.6 0.3 0.1 13.2 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXL50920.1 - 0.16 11.2 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PROL5-SMR PF15621.6 KXL50920.1 - 0.24 11.9 1.6 0.71 10.4 1.6 1.8 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family tRNA-synt_2b PF00587.25 KXL50923.1 - 0.13 12.2 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) Cys_Met_Meta_PP PF01053.20 KXL50924.1 - 3.4e-57 193.7 0.0 4.7e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KXL50924.1 - 5.5e-05 22.3 0.0 8.7e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KXL50924.1 - 0.0055 15.9 0.0 0.009 15.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Pro_isomerase PF00160.21 KXL50926.1 - 1.9e-43 148.5 0.1 2.1e-43 148.3 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TraL PF07178.11 KXL50927.1 - 0.049 14.1 2.0 0.34 11.4 0.1 2.1 1 1 0 2 2 2 0 TraL protein ENTH PF01417.20 KXL50928.1 - 1.2e-48 164.3 0.6 1.8e-48 163.7 0.6 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KXL50928.1 - 0.0008 18.5 0.1 0.0011 18.0 0.1 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 KXL50928.1 - 0.062 13.2 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 VHS domain DUF5102 PF17104.5 KXL50928.1 - 0.72 9.8 6.3 7.8 6.4 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) Ribosomal_L14 PF00238.19 KXL50929.1 - 1.2e-34 119.0 0.0 1.4e-34 118.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e adh_short PF00106.25 KXL50930.1 - 6.9e-31 107.2 0.0 9.6e-31 106.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL50930.1 - 5.7e-17 62.1 0.0 7.4e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXL50930.1 - 4.9e-08 33.1 0.0 7.1e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXL50930.1 - 0.00072 19.5 0.0 0.0016 18.3 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXL50930.1 - 0.0012 18.4 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family C2 PF00168.30 KXL50931.1 - 6.7e-80 264.0 1.4 1.2e-20 73.7 0.0 5.5 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 KXL50931.1 - 1e-05 25.1 0.0 1.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain UDPGP PF01704.18 KXL50932.1 - 3.7e-190 631.9 0.0 4.3e-190 631.7 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase LIP PF03583.14 KXL50933.1 - 0.093 12.0 0.0 0.095 12.0 0.0 1.1 1 0 0 1 1 1 0 Secretory lipase FolB PF02152.18 KXL50934.1 - 6.4e-23 81.4 0.0 1.1e-16 61.4 0.1 2.2 2 0 0 2 2 2 2 Dihydroneopterin aldolase Cu-oxidase_3 PF07732.15 KXL50935.1 - 1.1e-42 144.8 1.3 1.1e-42 144.8 1.3 3.5 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXL50935.1 - 2e-34 118.3 13.4 4.1e-27 94.6 3.6 4.8 3 2 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 KXL50935.1 - 7.6e-31 107.4 3.8 2.2e-30 105.9 0.0 3.0 4 0 0 4 4 4 1 Multicopper oxidase Aldose_epim PF01263.20 KXL50936.1 - 5.7e-50 170.3 0.9 7e-50 170.0 0.9 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Arm-DNA-bind_2 PF12167.8 KXL50936.1 - 0.11 12.4 0.0 0.41 10.6 0.0 1.9 2 0 0 2 2 2 0 Arm DNA-binding domain GIT_SHD PF08518.11 KXL50937.1 - 3.2e-23 81.0 8.3 5.5e-12 45.1 1.5 2.8 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT DUF3584 PF12128.8 KXL50937.1 - 0.0082 13.7 51.6 0.012 13.2 51.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Filament PF00038.21 KXL50937.1 - 0.044 13.4 55.3 0.066 12.8 21.1 3.1 1 1 2 3 3 3 0 Intermediate filament protein Phage_tail_APC PF16778.5 KXL50937.1 - 0.12 12.3 2.8 0.6 10.0 2.8 2.3 1 0 0 1 1 1 0 Phage tail assembly chaperone protein Spc7 PF08317.11 KXL50937.1 - 0.17 10.8 59.5 0.092 11.6 26.6 2.6 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF4515 PF14988.6 KXL50937.1 - 1.4 8.7 55.9 1.3 8.8 28.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4515) HOOK PF05622.12 KXL50937.1 - 2.3 6.2 52.9 3.5 5.7 52.9 1.1 1 0 0 1 1 1 0 HOOK protein Golgin_A5 PF09787.9 KXL50937.1 - 2.5 7.5 62.5 0.15 11.5 31.2 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 HMMR_N PF15905.5 KXL50937.1 - 7.7 5.9 55.3 0.09 12.2 23.6 2.4 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal ATG16 PF08614.11 KXL50937.1 - 8.6 6.5 64.7 1.8 8.7 32.4 3.6 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF3605 PF12239.8 KXL50938.1 - 4.9e-56 189.3 0.0 7.3e-56 188.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Ammonium_transp PF00909.21 KXL50939.1 - 1.3e-82 277.7 32.9 1.4e-82 277.5 32.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family HMG-CoA_red PF00368.18 KXL50940.1 - 3.3e-140 467.3 2.1 4.7e-140 466.8 2.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 KXL50940.1 - 3.4e-38 130.9 0.0 6.9e-38 130.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 KXL50940.1 - 1.3e-12 47.8 1.0 2.8e-12 46.7 1.0 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KXL50940.1 - 2e-06 26.2 0.4 2e-06 26.2 0.4 1.4 2 0 0 2 2 2 1 Patched family Aminotran_5 PF00266.19 KXL50940.1 - 2.1e-05 23.7 0.0 4.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KXL50940.1 - 0.17 10.3 0.0 0.46 9.0 0.0 1.6 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme IDO PF01231.18 KXL50941.1 - 1.2e-148 495.5 0.0 1.4e-148 495.3 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.11 KXL50941.1 - 0.0046 15.7 0.0 0.28 9.9 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1864) Zn_clus PF00172.18 KXL50942.1 - 2.7e-07 30.6 11.3 4.8e-07 29.8 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXL50942.1 - 2.8e-07 29.9 0.0 4.5e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Hydrolase PF00702.26 KXL50943.1 - 5.2e-05 23.6 0.0 9.9e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXL50943.1 - 9e-05 22.6 0.0 0.00014 22.0 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KXL50943.1 - 0.049 13.8 0.0 0.56 10.3 0.0 2.6 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase FPV060 PF17614.2 KXL50943.1 - 0.12 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Viral CC-type chemokine Glyco_hydro_63 PF03200.16 KXL50944.1 - 1.2e-07 30.8 13.1 9e-06 24.7 1.0 4.7 5 1 0 5 5 5 3 Glycosyl hydrolase family 63 C-terminal domain Sugar_tr PF00083.24 KXL50945.1 - 4.4e-14 52.2 0.7 5.6e-09 35.4 0.2 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter ATP-synt_ab PF00006.25 KXL50946.1 - 1.8e-67 227.1 0.0 2.5e-67 226.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KXL50946.1 - 1.4e-13 51.2 0.8 3.3e-13 50.0 0.8 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain LIM_bind PF01803.16 KXL50948.1 - 5.4e-50 170.2 0.4 5.4e-50 170.2 0.4 3.0 4 0 0 4 4 4 1 LIM-domain binding protein TPR_1 PF00515.28 KXL50952.1 - 9.3e-56 183.5 22.6 1e-08 34.6 0.0 10.8 11 1 0 11 11 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 KXL50952.1 - 9.2e-51 165.9 16.1 1.3e-06 28.0 0.0 10.4 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 KXL50952.1 - 1.6e-40 133.9 16.4 3e-07 30.1 0.0 10.7 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_17 PF13431.6 KXL50952.1 - 2.6e-28 96.3 10.9 4.7e-05 23.5 0.1 10.8 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_11 PF13414.6 KXL50952.1 - 3.7e-27 93.7 15.5 8.8e-07 28.5 0.9 8.9 6 2 2 8 8 8 5 TPR repeat TPR_14 PF13428.6 KXL50952.1 - 9.6e-24 82.1 18.4 0.00018 22.1 0.0 9.6 6 3 5 11 11 10 7 Tetratricopeptide repeat TPR_19 PF14559.6 KXL50952.1 - 1.3e-23 83.3 13.1 3.7e-05 24.2 0.0 8.0 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 KXL50952.1 - 4.4e-23 81.7 11.5 3.1e-06 27.7 0.0 7.3 5 2 1 7 7 7 5 Tetratricopeptide repeat TPR_6 PF13174.6 KXL50952.1 - 1.8e-22 78.4 17.3 0.0023 18.4 0.0 9.7 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.6 KXL50952.1 - 4e-22 78.3 18.4 2.5e-05 24.5 0.5 7.8 5 3 1 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 KXL50952.1 - 2.3e-21 74.2 10.2 0.0087 16.0 0.1 9.6 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_9 PF13371.6 KXL50952.1 - 1.6e-15 57.0 10.6 0.00054 20.1 0.0 7.3 5 2 3 8 8 7 5 Tetratricopeptide repeat ANAPC3 PF12895.7 KXL50952.1 - 2.1e-10 40.7 9.2 1.6e-06 28.3 1.7 3.8 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 KXL50952.1 - 2e-08 34.2 3.4 0.036 13.8 0.1 4.3 3 2 0 4 4 3 3 Tetratricopeptide repeat-like domain TPR_15 PF13429.6 KXL50952.1 - 6.2e-08 32.2 10.4 0.0011 18.3 0.5 5.5 1 1 3 4 4 4 4 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXL50952.1 - 0.00028 20.9 0.1 12 6.1 0.0 4.4 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat DUF2225 PF09986.9 KXL50952.1 - 0.01 15.6 1.3 1.4 8.5 0.0 3.2 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) BTAD PF03704.17 KXL50952.1 - 0.013 16.0 13.3 0.49 10.8 0.2 4.6 4 1 0 4 4 4 0 Bacterial transcriptional activator domain TPR_10 PF13374.6 KXL50952.1 - 0.022 14.6 17.6 14 5.7 0.2 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat ChAPs PF09295.10 KXL50952.1 - 0.042 12.8 2.6 4.7 6.1 0.1 3.1 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) SNAP PF14938.6 KXL50952.1 - 0.094 12.1 12.4 11 5.3 0.1 4.8 1 1 1 4 4 4 0 Soluble NSF attachment protein, SNAP Oxysterol_BP PF01237.18 KXL50954.1 - 2.6e-90 303.0 0.0 2e-87 293.4 0.0 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein Glyco_hydro_47 PF01532.20 KXL50955.1 - 4.4e-92 309.4 0.0 5e-92 309.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Phos_pyr_kin PF08543.12 KXL50957.1 - 1.7e-80 270.0 1.5 1.7e-80 270.0 1.5 1.6 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase DEAD PF00270.29 KXL50957.1 - 2.5e-49 167.4 0.0 2.8e-48 164.0 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase TENA_THI-4 PF03070.16 KXL50957.1 - 5.2e-49 166.9 3.1 5.2e-49 166.9 3.1 1.8 2 0 0 2 2 2 1 TENA/THI-4/PQQC family Helicase_C PF00271.31 KXL50957.1 - 1.9e-30 105.5 0.0 4.6e-30 104.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PfkB PF00294.24 KXL50957.1 - 1.6e-05 24.4 0.2 9.5e-05 21.8 0.0 2.2 2 1 0 2 2 2 1 pfkB family carbohydrate kinase ResIII PF04851.15 KXL50957.1 - 0.00055 20.0 0.0 0.0017 18.3 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 KXL50957.1 - 0.013 15.6 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain AAA_19 PF13245.6 KXL50957.1 - 0.017 15.5 0.0 11 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Peroxin-22 PF12827.7 KXL50957.1 - 0.024 14.5 0.0 0.87 9.5 0.0 2.4 2 0 0 2 2 2 0 Peroxisomal biogenesis protein family Rad9 PF04139.13 KXL50958.1 - 1.9e-55 188.1 1.4 2.3e-55 187.8 1.4 1.1 1 0 0 1 1 1 1 Rad9 RCC1 PF00415.18 KXL50959.1 - 5.3e-35 119.8 18.6 2.2e-11 44.2 0.1 7.8 8 1 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KXL50959.1 - 9.4e-30 101.8 27.7 6.1e-07 29.1 0.8 7.5 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Methyltranf_PUA PF13636.6 KXL50959.1 - 0.13 12.3 0.7 4.5 7.3 0.1 2.6 2 0 0 2 2 2 0 RNA-binding PUA-like domain of methyltransferase RsmF Ribosomal_S9 PF00380.19 KXL50960.1 - 2.2e-33 115.4 0.2 2.4e-33 115.2 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 SMC_Nse1 PF07574.13 KXL50961.1 - 1.4e-64 217.5 0.2 1.8e-64 217.2 0.2 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 KXL50961.1 - 2.7e-11 43.6 13.2 5.2e-11 42.7 13.2 1.5 1 0 0 1 1 1 1 RING-like domain zf-ANAPC11 PF12861.7 KXL50961.1 - 0.00017 21.6 3.2 0.00031 20.8 3.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KXL50961.1 - 0.049 14.0 11.0 0.09 13.1 11.0 1.5 1 0 0 1 1 1 0 Ring finger domain RIH_assoc PF08454.11 KXL50961.1 - 0.17 11.8 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 RyR and IP3R Homology associated Baculo_IE-1 PF05290.11 KXL50961.1 - 3.9 7.4 6.8 0.92 9.5 3.1 1.7 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Synaptobrevin PF00957.21 KXL50962.1 - 2.9e-14 52.6 0.5 5e-14 51.8 0.5 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KXL50962.1 - 3e-14 52.8 0.0 6.5e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain YL1_C PF08265.11 KXL50963.1 - 1.3e-17 63.2 2.0 2.5e-17 62.3 2.0 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Lactamase_B PF00753.27 KXL50964.1 - 4.5e-06 26.8 2.7 9.2e-06 25.8 2.6 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily BUD22 PF09073.10 KXL50966.1 - 0.017 14.5 15.5 0.021 14.2 15.5 1.1 1 0 0 1 1 1 0 BUD22 LON_substr_bdg PF02190.16 KXL50967.1 - 3.2e-24 86.0 0.0 5.1e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 KXL50967.1 - 2e-12 46.7 15.8 2.3e-10 40.1 9.4 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXL50967.1 - 4.9e-11 42.5 17.9 2.3e-08 33.9 3.8 2.8 2 1 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KXL50967.1 - 2.8e-10 40.2 20.6 3.5e-06 27.1 9.1 2.6 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KXL50967.1 - 2.6e-09 36.8 15.8 2.6e-06 27.2 8.2 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXL50967.1 - 7.1e-09 35.5 18.8 7.2e-06 25.9 8.5 2.4 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_2 PF13639.6 KXL50967.1 - 3.7e-08 33.5 19.7 1.7e-07 31.4 9.0 2.6 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.6 KXL50967.1 - 3.8e-08 33.1 19.1 5.8e-07 29.3 8.5 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXL50967.1 - 5e-05 23.1 17.7 0.00028 20.7 7.3 2.6 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KXL50967.1 - 0.001 19.3 4.5 0.0038 17.5 4.5 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 KXL50967.1 - 0.0095 16.1 16.8 0.013 15.6 7.9 2.7 2 0 0 2 2 2 1 zinc RING finger of MSL2 U-box PF04564.15 KXL50967.1 - 0.029 14.5 0.1 0.18 12.0 0.0 2.2 2 0 0 2 2 2 0 U-box domain zf-RING_6 PF14835.6 KXL50967.1 - 0.053 13.4 17.1 0.2 11.6 3.8 2.9 3 0 0 3 3 3 0 zf-RING of BARD1-type protein HTH_31 PF13560.6 KXL50967.1 - 0.056 13.8 0.1 0.33 11.3 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain zf-RING_4 PF14570.6 KXL50967.1 - 0.056 13.2 11.9 0.025 14.4 5.1 2.9 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain HTH_25 PF13413.6 KXL50967.1 - 0.14 12.1 0.0 0.38 10.6 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain zf-Nse PF11789.8 KXL50967.1 - 0.27 11.1 13.9 0.12 12.2 5.0 2.4 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit TPR_1 PF00515.28 KXL50968.1 - 9.1e-15 53.8 3.9 1.8e-07 30.7 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXL50968.1 - 2.6e-13 49.0 4.5 2.2e-05 24.2 0.0 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat PB1 PF00564.24 KXL50968.1 - 1.3e-11 44.3 0.3 2.8e-11 43.2 0.3 1.5 1 0 0 1 1 1 1 PB1 domain TPR_12 PF13424.6 KXL50968.1 - 5e-10 39.5 0.7 3.2e-06 27.3 0.1 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXL50968.1 - 2.5e-09 36.6 1.6 9e-05 22.4 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KXL50968.1 - 1.5e-07 31.6 2.4 0.08 13.6 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXL50968.1 - 1.9e-05 24.3 0.5 0.00064 19.4 0.2 3.0 1 1 1 2 2 2 1 TPR repeat TPR_7 PF13176.6 KXL50968.1 - 2.8e-05 23.8 4.7 0.00023 20.9 0.1 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXL50968.1 - 0.0007 19.8 0.1 7.3 7.2 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXL50968.1 - 0.018 15.7 0.2 0.018 15.7 0.2 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXL50968.1 - 0.056 13.3 2.2 0.24 11.3 0.0 3.1 3 1 1 4 4 3 0 Tetratricopeptide repeat Il2rg PF15874.5 KXL50968.1 - 0.094 13.0 0.0 0.3 11.4 0.0 1.8 1 0 0 1 1 1 0 Putative Interleukin 2 receptor, gamma chain TPR_14 PF13428.6 KXL50968.1 - 0.33 11.9 0.1 0.33 11.9 0.1 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.10 KXL50969.1 - 6.3e-152 506.2 0.0 8.2e-152 505.8 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 KXL50969.1 - 0.00014 22.3 0.0 0.26 11.8 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXL50969.1 - 0.0012 18.8 0.3 0.44 10.8 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXL50969.1 - 0.0045 17.7 3.6 1 10.4 0.1 4.5 3 2 1 4 4 4 1 Tetratricopeptide repeat NYD-SP12_N PF15015.6 KXL50969.1 - 0.16 10.3 0.0 0.24 9.7 0.0 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal TPR_17 PF13431.6 KXL50970.1 - 0.012 16.0 0.0 19 5.9 0.0 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat CRAL_TRIO_N PF03765.15 KXL50970.1 - 0.051 13.8 0.1 0.21 11.8 0.1 2.1 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain TPR_11 PF13414.6 KXL50970.1 - 0.19 11.4 0.4 4.1 7.2 1.1 2.7 2 0 0 2 2 2 0 TPR repeat TPR_16 PF13432.6 KXL50970.1 - 1 10.1 3.3 2 9.2 0.6 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF4790 PF16037.5 KXL50970.1 - 2.3 8.7 5.2 2.5 8.6 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4790) DUF3292 PF11696.8 KXL50971.1 - 1.8e-297 988.1 0.0 2.1e-297 987.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) Pex24p PF06398.11 KXL50971.1 - 0.021 13.8 0.0 0.028 13.4 0.0 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin PRT_C PF08372.10 KXL50971.1 - 0.07 12.9 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal Methyltransf_3 PF01596.17 KXL50973.1 - 2.2e-28 98.9 0.0 2.5e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KXL50973.1 - 1e-11 45.8 0.0 2.1e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL50973.1 - 7.1e-09 35.6 0.0 1.3e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXL50973.1 - 2.3e-05 24.0 0.0 4.3e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 KXL50973.1 - 7.8e-05 23.3 0.0 0.00019 22.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXL50973.1 - 0.00016 21.5 0.0 0.00036 20.4 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.12 KXL50973.1 - 0.003 17.3 0.0 0.0083 15.9 0.0 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF938) Cons_hypoth95 PF03602.15 KXL50973.1 - 0.0051 16.5 0.0 0.0071 16.0 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 KXL50973.1 - 0.0057 16.2 0.0 0.0097 15.5 0.0 1.4 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.7 KXL50973.1 - 0.016 15.2 0.0 0.062 13.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 KXL50973.1 - 0.17 11.7 0.0 0.31 10.9 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain TFIIB PF00382.19 KXL50974.1 - 7e-28 96.5 0.2 3.4e-17 62.2 0.0 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 KXL50974.1 - 6.3e-20 71.4 0.1 6.3e-20 71.4 0.1 4.1 3 2 1 4 4 4 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 KXL50974.1 - 0.001 18.5 3.4 0.0024 17.3 3.4 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 KXL50974.1 - 0.033 13.9 0.1 0.14 11.9 0.0 2.0 1 1 1 2 2 2 0 Cyclin, N-terminal domain PHD PF00628.29 KXL50975.1 - 7.4e-12 45.0 6.6 1.3e-11 44.2 6.6 1.4 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 KXL50975.1 - 0.00012 22.0 3.4 0.00024 20.9 3.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-PHD-like PF15446.6 KXL50975.1 - 0.012 15.2 2.1 0.033 13.8 2.1 1.7 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 KXL50975.1 - 0.02 14.4 8.2 0.09 12.3 8.2 2.1 1 1 0 1 1 1 0 PHD-finger FYVE_2 PF02318.16 KXL50975.1 - 0.13 12.5 1.2 0.23 11.7 1.2 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger zf-piccolo PF05715.13 KXL50975.1 - 0.14 12.3 2.5 0.29 11.3 2.5 1.5 1 0 0 1 1 1 0 Piccolo Zn-finger C1_1 PF00130.22 KXL50975.1 - 0.34 10.8 3.2 0.39 10.6 0.6 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RRPl_C4 PF17026.5 KXL50975.1 - 1.3 9.2 3.9 4.4 7.5 3.9 1.8 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type PHD_4 PF16866.5 KXL50975.1 - 1.9 8.7 7.7 6 7.0 7.7 1.9 1 1 0 1 1 1 0 PHD-finger Abhydrolase_3 PF07859.13 KXL50976.1 - 1.4e-44 152.4 0.0 4e-34 118.3 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 KXL50976.1 - 5.4e-10 38.8 0.0 1.1e-09 37.8 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase PF07224.11 KXL50976.1 - 0.15 11.1 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.7 KXL50976.1 - 0.2 10.5 0.0 0.45 9.4 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme DUF2974 PF11187.8 KXL50976.1 - 0.21 11.1 0.0 0.32 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DASH_Dad4 PF08650.10 KXL50977.1 - 1.9e-33 114.3 6.6 2e-33 114.1 6.6 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 GM_CSF PF01109.17 KXL50977.1 - 0.0036 17.4 0.4 0.0042 17.2 0.4 1.1 1 0 0 1 1 1 1 Granulocyte-macrophage colony-stimulating factor DASH_Dad1 PF08649.10 KXL50977.1 - 0.1 12.8 4.5 0.17 12.1 4.5 1.4 1 1 0 1 1 1 0 DASH complex subunit Dad1 Sec63 PF02889.16 KXL50978.1 - 8e-139 461.1 0.1 1.4e-80 270.1 0.1 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KXL50978.1 - 3.5e-53 180.0 0.4 3.7e-27 95.2 1.4 3.5 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 KXL50978.1 - 1e-22 81.0 0.0 1.3e-11 44.8 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXL50978.1 - 4.2e-17 62.5 0.0 4.9e-07 30.1 0.0 4.8 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KXL50978.1 - 3e-08 34.0 0.3 0.0025 18.1 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KXL50978.1 - 3.2e-07 30.3 0.8 0.0098 15.6 0.6 2.9 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 KXL50978.1 - 2.1e-06 28.1 1.4 0.0016 18.8 1.4 2.9 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KXL50978.1 - 0.0016 18.9 0.4 5.4 7.4 0.0 3.8 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Helicase_PWI PF18149.1 KXL50978.1 - 0.0043 17.2 0.0 0.014 15.6 0.0 1.8 1 0 0 1 1 1 1 N-terminal helicase PWI domain IstB_IS21 PF01695.17 KXL50978.1 - 0.036 13.8 0.2 11 5.7 0.0 3.5 4 0 0 4 4 4 0 IstB-like ATP binding protein Helicase_RecD PF05127.14 KXL50978.1 - 0.16 11.8 0.1 3.6 7.4 0.2 2.6 2 0 0 2 2 2 0 Helicase TniB PF05621.11 KXL50978.1 - 0.66 9.4 4.6 24 4.3 0.4 4.0 3 1 0 4 4 4 0 Bacterial TniB protein BTB PF00651.31 KXL50979.1 - 0.035 14.3 0.0 0.067 13.4 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain zf-CXXC PF02008.20 KXL50979.1 - 0.15 12.1 0.4 0.15 12.1 0.4 1.9 2 0 0 2 2 2 0 CXXC zinc finger domain Usp PF00582.26 KXL50980.1 - 3.4e-21 76.2 0.0 4.8e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family DUF4944 PF16302.5 KXL50980.1 - 0.054 13.5 0.3 0.079 13.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4944) ABA_GPCR PF12430.8 KXL50981.1 - 5.2e-56 189.3 2.8 5.2e-56 189.3 2.8 2.3 2 1 1 3 3 3 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 KXL50981.1 - 7.9e-22 77.1 0.2 3.3e-21 75.1 0.0 2.1 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal Trm112p PF03966.16 KXL50982.1 - 0.14 12.8 0.0 0.19 12.3 0.0 1.3 1 0 0 1 1 1 0 Trm112p-like protein TFIIA PF03153.13 KXL50983.1 - 0.0023 18.0 12.8 0.0034 17.4 12.8 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit MCU PF04678.13 KXL50983.1 - 0.18 11.9 1.8 0.28 11.2 1.8 1.4 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Spt20 PF12090.8 KXL50983.1 - 0.2 11.3 18.7 0.33 10.5 18.7 1.3 1 0 0 1 1 1 0 Spt20 family Neur_chan_memb PF02932.16 KXL50983.1 - 1.5 8.9 3.4 2.5 8.1 3.4 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PCEMA1 PF07418.11 KXL50983.1 - 1.6 8.2 8.1 0.3 10.6 4.5 1.6 2 0 0 2 2 2 0 Acidic phosphoprotein precursor PCEMA1 EFTUD2 PF16004.5 KXL50983.1 - 2.2 8.9 11.3 5.6 7.6 11.3 1.7 1 1 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus MAS20 PF02064.15 KXL50983.1 - 3 7.9 10.3 5.4 7.1 10.3 1.4 1 0 0 1 1 1 0 MAS20 protein import receptor Roughex PF06020.11 KXL50983.1 - 4.9 6.1 12.0 7.8 5.5 12.0 1.3 1 0 0 1 1 1 0 Drosophila roughex protein DUF4834 PF16118.5 KXL50983.1 - 9 7.3 7.7 19 6.3 7.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Methyltransf_23 PF13489.6 KXL50984.1 - 9e-23 80.9 0.0 1.1e-22 80.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL50984.1 - 3.7e-08 34.0 0.0 9.5e-08 32.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL50984.1 - 1.1e-06 28.5 0.0 2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL50984.1 - 2.8e-06 28.0 0.0 5.5e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL50984.1 - 9.3e-06 26.2 0.0 2.1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXL50984.1 - 0.08 12.3 0.0 0.1 11.9 0.0 1.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXL50984.1 - 0.13 11.7 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DAO PF01266.24 KXL50985.1 - 7.6e-41 140.9 0.2 9e-41 140.6 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXL50985.1 - 1.2e-05 24.7 0.0 0.025 13.8 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXL50985.1 - 1.7e-05 24.9 0.0 0.041 13.9 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXL50985.1 - 6.3e-05 23.1 0.0 0.00018 21.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KXL50985.1 - 0.00032 19.9 0.0 0.0039 16.3 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 KXL50985.1 - 0.0098 15.2 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 1 Thi4 family K_oxygenase PF13434.6 KXL50985.1 - 0.27 10.3 0.0 0.72 8.9 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) TBP PF00352.21 KXL50986.1 - 2.1e-67 223.1 0.1 1e-32 111.9 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KXL50986.1 - 4.6e-05 23.5 0.0 0.24 11.5 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 KXL50986.1 - 0.14 12.0 0.1 0.72 9.7 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) ETF_QO PF05187.13 KXL50987.1 - 1.3e-48 163.4 1.1 2.3e-48 162.6 1.1 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 KXL50987.1 - 1.1e-08 35.1 0.0 0.00025 20.7 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXL50987.1 - 2.1e-06 27.9 0.0 7.4e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXL50987.1 - 3.2e-06 26.5 0.1 0.0062 15.7 0.2 2.4 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KXL50987.1 - 9.1e-06 25.1 0.0 3.6e-05 23.1 0.0 1.8 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXL50987.1 - 0.00029 20.2 0.0 0.012 14.9 0.0 2.3 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 KXL50987.1 - 0.00032 20.2 0.0 0.00049 19.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXL50987.1 - 0.00037 21.0 0.2 1 10.0 0.0 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXL50987.1 - 0.00047 19.5 0.1 0.0015 17.8 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KXL50987.1 - 0.00079 18.2 0.1 0.0012 17.7 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.14 KXL50987.1 - 0.0017 17.3 0.0 0.24 10.2 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_9 PF13454.6 KXL50987.1 - 0.0021 18.1 0.0 0.0053 16.7 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KXL50987.1 - 0.013 14.8 0.1 0.019 14.2 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.7 KXL50987.1 - 0.028 15.0 0.8 0.077 13.6 0.8 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain Lycopene_cycl PF05834.12 KXL50987.1 - 0.062 12.3 0.1 0.091 11.8 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Fer4_2 PF12797.7 KXL50987.1 - 0.14 12.3 0.7 0.44 10.8 0.7 1.8 1 0 0 1 1 1 0 4Fe-4S binding domain GIDA PF01134.22 KXL50987.1 - 0.15 11.1 0.1 0.22 10.6 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A RRM_1 PF00076.22 KXL50988.1 - 1e-22 79.7 0.1 3.7e-11 42.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXL50988.1 - 0.00066 19.5 0.0 0.28 11.1 0.0 2.1 2 0 0 2 2 2 2 Occluded RNA-recognition motif IBR PF01485.21 KXL50989.1 - 1.6e-12 47.5 43.5 8.8e-07 29.1 13.6 3.6 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain SUIM_assoc PF16619.5 KXL50989.1 - 0.021 14.9 0.3 0.021 14.9 0.3 3.0 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF2158 PF09926.9 KXL50989.1 - 0.035 13.9 0.1 0.075 12.8 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2158) zf-CCHC PF00098.23 KXL50989.1 - 1.6 8.9 13.8 0.37 11.0 0.3 3.7 4 0 0 4 4 4 0 Zinc knuckle AMP-binding PF00501.28 KXL50990.1 - 6e-63 212.9 0.0 8.8e-63 212.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KXL50990.1 - 3.7e-61 206.5 0.0 5.7e-61 205.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KXL50990.1 - 4.3e-09 36.6 0.0 1.3e-08 35.1 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 KXL50990.1 - 0.00019 21.0 0.0 0.00036 20.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXL50990.1 - 0.00045 19.3 0.1 0.0035 16.4 0.1 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 KXL50990.1 - 0.025 15.6 0.0 3.8 8.6 0.0 2.9 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain RmlD_sub_bind PF04321.17 KXL50990.1 - 0.15 11.1 0.0 0.96 8.5 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain Glyco_hydro_1 PF00232.18 KXL50991.1 - 3.5e-104 348.7 6.4 5.7e-104 348.1 6.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 CBM_10 PF02013.16 KXL50991.1 - 1 9.9 3.2 1.2 9.7 1.2 2.1 2 0 0 2 2 2 0 Cellulose or protein binding domain Hva1_TUDOR PF11160.8 KXL50992.1 - 1.9e-16 60.0 2.7 1.9e-16 60.0 2.7 2.6 2 1 0 2 2 2 1 Hypervirulence associated proteins TUDOR domain UPF0492 PF15744.5 KXL50992.1 - 0.31 10.2 15.4 0.093 11.9 12.6 1.4 1 1 0 1 1 1 0 Uncharacterized protein family UPF0492 PAP_assoc PF03828.19 KXL50994.1 - 7.6e-20 70.9 0.0 1.9e-19 69.6 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KXL50994.1 - 0.00029 21.0 0.0 0.00065 19.9 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KXL50994.1 - 0.075 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase MOZART1 PF12554.8 KXL50994.1 - 0.2 11.5 0.1 0.44 10.4 0.1 1.5 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated DUF383 PF04063.14 KXL50995.1 - 1.5e-66 223.7 0.2 5e-65 218.7 0.0 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF383) DUF384 PF04064.13 KXL50995.1 - 2.1e-21 75.5 0.4 5.3e-21 74.2 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Pkinase PF00069.25 KXL50996.1 - 4.4e-41 141.0 0.1 3.7e-22 78.9 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXL50996.1 - 1e-13 51.2 0.4 7.7e-10 38.5 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXL50996.1 - 0.096 11.4 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase FA_hydroxylase PF04116.13 KXL50997.1 - 1.4e-25 90.2 18.7 1.4e-25 90.2 18.7 2.0 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily NCA2 PF08637.10 KXL50998.1 - 5.2e-108 360.6 0.0 8.3e-108 359.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Abhydrolase_1 PF00561.20 KXL50999.1 - 1.1e-15 58.0 0.9 5.7e-08 32.7 0.3 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXL50999.1 - 4.2e-07 29.5 0.2 0.011 15.1 0.1 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXL50999.1 - 5.1e-07 30.5 0.1 8.2e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXL50999.1 - 0.022 14.3 0.0 4.9 6.6 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family FAST_2 PF08368.12 KXL50999.1 - 0.1 13.4 0.0 0.44 11.4 0.0 1.9 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 2 Peptidase_S10 PF00450.22 KXL50999.1 - 0.13 11.7 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase Ras PF00071.22 KXL51000.1 - 1.1e-65 220.2 0.1 1.3e-65 220.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXL51000.1 - 3.3e-34 117.7 0.1 4.4e-34 117.3 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXL51000.1 - 1.3e-13 50.8 0.0 1.5e-13 50.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXL51000.1 - 4.5e-06 26.3 0.0 9.6e-06 25.3 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KXL51000.1 - 0.00011 21.7 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KXL51000.1 - 0.0015 18.4 0.1 1.9 8.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KXL51000.1 - 0.0026 17.8 0.0 0.0047 17.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KXL51000.1 - 0.01 15.3 0.0 0.012 15.1 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KXL51000.1 - 0.022 14.3 0.0 0.14 11.7 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA PF00004.29 KXL51000.1 - 0.068 13.6 0.0 4.2 7.8 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXL51000.1 - 0.085 13.1 0.1 0.37 11.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain UCH PF00443.29 KXL51001.1 - 2e-36 125.8 0.2 2.9e-32 112.2 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXL51001.1 - 1.2e-08 35.0 2.6 2.6e-07 30.5 2.6 2.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Thiolase_N PF00108.23 KXL51002.1 - 2.5e-76 256.5 0.3 3.6e-76 256.0 0.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXL51002.1 - 4.3e-44 149.1 0.4 2.7e-43 146.5 0.2 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXL51002.1 - 0.0046 16.6 0.9 0.0046 16.6 0.9 1.9 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Polysacc_deac_2 PF04748.13 KXL51002.1 - 0.046 12.9 0.0 0.1 11.8 0.0 1.6 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase DUF3245 PF11595.8 KXL51003.1 - 1.3e-14 54.9 10.7 1.3e-14 54.9 10.7 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF3245) DUF4672 PF15716.5 KXL51003.1 - 2.3 7.8 8.6 0.064 12.9 2.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4672) CBFD_NFYB_HMF PF00808.23 KXL51004.1 - 6.6e-15 55.1 0.5 1.8e-12 47.3 0.3 2.3 2 0 0 2 2 2 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXL51004.1 - 0.025 15.0 3.3 0.2 12.0 0.7 2.6 2 1 0 2 2 2 0 Core histone H2A/H2B/H3/H4 ABC1 PF03109.16 KXL51005.1 - 1.1e-22 80.4 0.0 5.2e-12 46.0 0.0 2.5 2 0 0 2 2 2 2 ABC1 family Sensor PF13796.6 KXL51005.1 - 0.0061 16.6 0.1 0.012 15.6 0.1 1.5 1 0 0 1 1 1 1 Putative sensor APH PF01636.23 KXL51005.1 - 0.04 13.8 0.3 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 KXL51005.1 - 0.12 12.0 0.0 0.47 10.0 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Raf1_HTH PF18579.1 KXL51005.1 - 0.16 11.7 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain Amidohydro_3 PF07969.11 KXL51006.1 - 2.4e-12 47.1 0.3 3.2e-08 33.5 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 KXL51006.1 - 1.8e-10 40.7 0.0 1.2e-09 38.0 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase family Glyco_hydro_3 PF00933.21 KXL51007.1 - 5.3e-63 213.3 0.0 7.5e-63 212.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 KXL51007.1 - 4.7e-05 23.6 0.0 0.00017 21.8 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Glyco_hydro_3_C PF01915.22 KXL51007.1 - 0.0045 17.0 0.0 0.0084 16.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain NDT80_PhoG PF05224.12 KXL51008.1 - 7.5e-34 117.6 0.0 1.2e-33 116.9 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family GH-E PF14410.6 KXL51009.1 - 0.062 13.7 0.2 0.17 12.3 0.2 1.7 1 0 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues DUF4769 PF15992.5 KXL51010.1 - 0.22 11.3 1.0 19 4.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4769) Peptidase_S10 PF00450.22 KXL51011.1 - 1.2e-89 301.7 1.2 1.6e-89 301.3 1.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase p450 PF00067.22 KXL51012.1 - 3e-45 154.8 0.5 7.1e-23 81.1 0.2 2.9 2 1 0 2 2 2 2 Cytochrome P450 COesterase PF00135.28 KXL51013.1 - 4.3e-68 230.4 1.3 2.5e-47 161.9 0.3 2.1 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KXL51013.1 - 0.035 13.9 0.1 0.1 12.5 0.1 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF4712 PF15830.5 KXL51013.1 - 0.31 10.7 0.1 0.5 10.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4712) adh_short PF00106.25 KXL51015.1 - 2e-17 63.3 0.0 7.4e-16 58.2 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL51015.1 - 2.9e-13 49.9 0.0 5.6e-13 49.0 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KXL51015.1 - 4.4e-06 26.3 0.0 5.1e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXL51015.1 - 3.4e-05 23.8 0.0 4.3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KXL51015.1 - 4.2e-05 23.5 0.0 5.6e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Pkinase PF00069.25 KXL51017.1 - 2e-70 237.2 0.0 7.4e-37 127.1 0.0 3.7 3 1 0 3 3 3 3 Protein kinase domain HGTP_anticodon2 PF12745.7 KXL51017.1 - 2.6e-46 158.3 3.5 2.6e-46 158.3 3.5 2.4 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.17 KXL51017.1 - 3.9e-40 137.8 0.0 1.4e-18 67.1 0.0 3.8 3 1 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 KXL51017.1 - 3.7e-16 59.5 1.5 1.7e-14 54.1 0.1 2.8 2 0 0 2 2 2 1 RWD domain tRNA-synt_His PF13393.6 KXL51017.1 - 3.7e-09 36.3 1.2 1.5e-08 34.3 0.0 2.6 3 1 0 3 3 3 1 Histidyl-tRNA synthetase Kinase-like PF14531.6 KXL51017.1 - 0.00028 20.3 0.0 0.77 9.0 0.0 2.5 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KXL51017.1 - 0.0023 17.9 1.5 0.0074 16.2 0.0 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family PAP_RNA-bind PF04926.15 KXL51017.1 - 0.0058 16.3 5.2 0.1 12.3 0.0 3.2 4 0 0 4 4 4 2 Poly(A) polymerase predicted RNA binding domain Cut12 PF11500.8 KXL51018.1 - 3.3e-22 79.0 11.6 1.2e-21 77.2 11.6 1.9 1 0 0 1 1 1 1 Spindle pole body formation-associated protein Myosin_head PF00063.21 KXL51019.1 - 6e-259 860.9 0.0 1.1e-258 860.0 0.0 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 KXL51019.1 - 3.2e-26 91.6 2.6 3.2e-26 91.6 2.6 2.8 2 1 0 2 2 2 1 DIL domain IQ PF00612.27 KXL51019.1 - 4.4e-11 41.6 39.2 0.00016 21.2 1.5 6.7 7 0 0 7 7 7 5 IQ calmodulin-binding motif Myosin_N PF02736.19 KXL51019.1 - 0.00052 19.8 1.0 0.0011 18.7 1.0 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain GAS PF13851.6 KXL51019.1 - 0.0086 15.4 38.4 0.068 12.5 22.0 2.8 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding AAA_22 PF13401.6 KXL51019.1 - 0.009 16.3 1.8 0.02 15.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXL51019.1 - 0.013 15.9 1.0 0.04 14.3 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain DUF3458 PF11940.8 KXL51019.1 - 0.018 15.5 0.9 0.068 13.6 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3458) Ig-like fold Sec34 PF04136.15 KXL51019.1 - 0.11 12.4 13.2 0.094 12.6 10.9 2.2 1 1 0 1 1 1 0 Sec34-like family Uso1_p115_C PF04871.13 KXL51019.1 - 0.67 10.3 36.0 5 7.5 12.5 2.8 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Fib_alpha PF08702.10 KXL51019.1 - 0.81 9.9 21.2 0.12 12.6 15.3 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Phage_GP20 PF06810.11 KXL51019.1 - 2.7 7.8 21.8 0.036 13.9 7.1 2.8 1 1 1 2 2 2 0 Phage minor structural protein GP20 Atg14 PF10186.9 KXL51019.1 - 3.8 6.5 35.7 5.1 6.1 15.2 2.5 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 KASH_CCD PF14662.6 KXL51019.1 - 6.1 6.6 36.6 0.038 13.8 12.9 2.8 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH APG6_N PF17675.1 KXL51019.1 - 6.5 7.3 45.1 1.1 9.7 29.3 3.6 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF1752 PF08550.10 KXL51020.1 - 5.9e-10 38.8 4.2 1.5e-09 37.5 4.2 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) AA_permease_2 PF13520.6 KXL51023.1 - 2.4e-49 168.3 43.6 2.6e-49 168.2 43.0 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXL51023.1 - 7.7e-25 87.4 36.8 1e-24 87.0 36.8 1.1 1 0 0 1 1 1 1 Amino acid permease YlaH PF14036.6 KXL51023.1 - 8.1 6.9 15.3 0.038 14.3 4.4 2.8 4 0 0 4 4 4 0 YlaH-like protein HCMV_UL124 PF17609.2 KXL51024.1 - 0.54 10.5 3.6 2.8 8.1 0.6 2.4 2 0 0 2 2 2 0 Family of unknown function SUR7 PF06687.12 KXL51025.1 - 4.7 6.8 14.2 0.034 13.8 4.9 2.1 2 0 0 2 2 2 0 SUR7/PalI family WD40 PF00400.32 KXL51027.1 - 3.4e-06 27.7 8.7 0.049 14.5 0.1 5.7 7 1 0 7 7 7 2 WD domain, G-beta repeat Dynein_IC2 PF11540.8 KXL51027.1 - 0.47 10.4 1.6 1.3 9.1 0.6 2.2 2 0 0 2 2 2 0 Cytoplasmic dynein 1 intermediate chain 2 ATP-synt_E PF05680.12 KXL51028.1 - 5.3e-20 71.6 0.0 5.9e-20 71.4 0.0 1.0 1 0 0 1 1 1 1 ATP synthase E chain DBP10CT PF08147.12 KXL51028.1 - 0.018 15.2 0.4 0.027 14.7 0.4 1.2 1 0 0 1 1 1 0 DBP10CT (NUC160) domain NADH_u_ox_C PF12853.7 KXL51028.1 - 0.046 13.7 0.1 1.9 8.5 0.0 2.1 2 0 0 2 2 2 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit TAFII55_N PF04658.13 KXL51029.1 - 4.6e-53 179.2 0.0 7.5e-53 178.5 0.0 1.3 1 0 0 1 1 1 1 TAFII55 protein conserved region DUF4477 PF14780.6 KXL51029.1 - 0.11 12.2 2.8 5.8 6.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4477) AAA_lid_9 PF17871.1 KXL51029.1 - 6.1 6.8 12.0 1.8 8.5 5.7 2.4 2 0 0 2 2 2 0 AAA lid domain DUF5341 PF17276.2 KXL51030.1 - 0.049 13.8 0.0 0.06 13.5 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5341) DUF761 PF05553.11 KXL51030.1 - 0.081 12.5 0.3 0.14 11.8 0.3 1.4 1 0 0 1 1 1 0 Cotton fibre expressed protein Cupin_2 PF07883.11 KXL51032.1 - 8.6e-05 22.2 0.1 0.00011 21.9 0.1 1.1 1 0 0 1 1 1 1 Cupin domain Cupin_7 PF12973.7 KXL51032.1 - 0.018 15.0 0.1 0.036 14.0 0.1 1.5 1 1 0 1 1 1 0 ChrR Cupin-like domain AAA PF00004.29 KXL51033.1 - 7.4e-41 139.7 0.0 1.4e-40 138.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXL51033.1 - 3.2e-05 23.7 0.0 7.7e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KXL51033.1 - 7.9e-05 23.0 0.0 0.0059 16.9 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KXL51033.1 - 9.2e-05 22.5 0.1 0.00046 20.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KXL51033.1 - 0.0003 21.0 0.0 0.00086 19.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KXL51033.1 - 0.00048 20.5 0.2 0.011 16.1 0.0 2.4 2 1 0 3 3 2 1 AAA ATPase domain DUF815 PF05673.13 KXL51033.1 - 0.0014 17.8 0.0 0.0026 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KXL51033.1 - 0.0095 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KXL51033.1 - 0.026 14.8 0.0 0.063 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KXL51033.1 - 0.032 13.7 0.0 0.098 12.2 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KXL51033.1 - 0.046 13.9 0.0 0.094 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXL51033.1 - 0.053 13.9 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 KXL51033.1 - 0.065 13.0 0.1 0.28 10.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_3 PF07726.11 KXL51033.1 - 0.087 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KXL51033.1 - 0.1 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KXL51033.1 - 0.14 12.0 1.3 0.54 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KXL51033.1 - 0.16 11.3 0.0 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 KXL51033.1 - 0.19 11.6 2.1 9.8 6.0 0.0 3.0 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Cpn60_TCP1 PF00118.24 KXL51034.1 - 3.6e-146 487.6 9.6 4.1e-146 487.5 9.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.12 KXL51034.1 - 0.064 12.9 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Protein X UAA PF08449.11 KXL51036.1 - 1.1e-82 277.7 9.9 1.6e-82 277.2 9.9 1.1 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 KXL51036.1 - 4.5e-06 26.0 5.3 1.8e-05 24.1 0.2 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.20 KXL51036.1 - 0.65 10.2 29.3 0.27 11.4 4.1 3.5 3 1 0 3 3 3 0 EamA-like transporter family HLH PF00010.26 KXL51038.1 - 1.3e-15 57.1 0.1 1.3e-15 57.1 0.1 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain MTTB PF06253.11 KXL51038.1 - 0.021 12.8 0.0 0.032 12.2 0.0 1.2 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) YabA PF06156.13 KXL51038.1 - 0.045 14.4 0.4 0.13 12.9 0.4 1.7 1 0 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 KXL51038.1 - 0.14 12.6 3.7 0.44 11.0 3.7 1.8 1 0 0 1 1 1 0 Cell division protein ZapB Phosphodiest PF01663.22 KXL51039.1 - 5.4e-91 305.8 1.2 7e-91 305.5 1.2 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KXL51039.1 - 1.5e-05 24.5 0.0 0.0055 16.1 0.0 2.3 1 1 0 2 2 2 2 Sulfatase SNARE PF05739.19 KXL51039.1 - 0.064 13.3 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 SNARE domain MFS_1 PF07690.16 KXL51040.1 - 2e-42 145.4 40.1 2e-42 145.4 40.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL51040.1 - 5.6e-07 28.8 35.4 1.9e-05 23.7 35.4 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter Glyco_hydro_43 PF04616.14 KXL51042.1 - 5.8e-28 98.0 3.6 1.2e-26 93.7 3.6 2.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 p450 PF00067.22 KXL51043.1 - 2.9e-25 89.0 0.0 1.3e-24 86.8 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 KXL51045.1 - 2.8e-24 85.6 0.0 4.9e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KXL51046.1 - 3.4e-34 118.3 27.0 7.3e-31 107.4 18.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL51046.1 - 1.6e-07 30.5 5.2 1.6e-07 30.5 5.2 1.9 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 KXL51046.1 - 9.9e-05 21.4 3.1 0.00025 20.0 2.0 3.4 3 1 1 4 4 4 2 MFS_1 like family MFS_5 PF05631.14 KXL51046.1 - 0.0085 15.1 0.5 0.0085 15.1 0.5 2.3 2 1 1 3 3 3 1 Sugar-tranasporters, 12 TM UQ_con PF00179.26 KXL51049.1 - 3.9e-11 42.8 0.0 6.3e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme tRNA-synt_2b PF00587.25 KXL51051.1 - 3e-19 69.7 0.0 1.1e-18 67.9 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KXL51051.1 - 1.3e-11 44.7 2.2 2.2e-11 43.9 2.2 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Acyl-CoA_dh_1 PF00441.24 KXL51052.1 - 9.1e-30 103.8 0.8 1.9e-29 102.8 0.8 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXL51052.1 - 3.2e-21 76.1 0.1 6.4e-21 75.1 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KXL51052.1 - 3.2e-20 72.1 0.0 5.7e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXL51052.1 - 1.7e-14 54.3 1.9 8.4e-14 52.0 0.3 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain SSF PF00474.17 KXL51053.1 - 7.5e-22 77.8 33.2 1.2e-21 77.1 33.2 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family B12D PF06522.11 KXL51053.1 - 0.62 9.9 1.9 6.4 6.7 0.0 3.6 3 0 0 3 3 3 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Acyl-CoA_dh_M PF02770.19 KXL51054.1 - 1.2e-20 73.5 0.1 1.9e-20 72.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KXL51054.1 - 5.4e-08 33.5 0.2 4.3e-07 30.6 0.2 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 KXL51054.1 - 2.7e-05 24.0 0.0 3.8e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Alpha-amylase_C PF02806.18 KXL51054.1 - 0.089 13.3 0.0 0.46 11.0 0.0 2.2 3 0 0 3 3 3 0 Alpha amylase, C-terminal all-beta domain NMO PF03060.15 KXL51055.1 - 7.2e-27 94.6 0.3 8.3e-27 94.4 0.3 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 KXL51055.1 - 8.5e-07 28.3 0.4 1.3e-06 27.7 0.4 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KXL51055.1 - 0.00015 20.9 3.4 0.00026 20.1 1.1 1.9 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.21 KXL51055.1 - 0.0032 16.7 2.1 0.0068 15.6 0.4 2.0 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.17 KXL51055.1 - 0.015 14.5 0.6 0.022 13.9 0.6 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase Radial_spoke_3 PF06098.11 KXL51055.1 - 0.065 12.5 0.2 0.095 12.0 0.2 1.2 1 0 0 1 1 1 0 Radial spoke protein 3 Asp PF00026.23 KXL51057.1 - 6.3e-08 32.4 3.8 8.8e-08 31.9 1.9 1.9 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXL51057.1 - 0.074 13.3 2.9 0.36 11.0 0.2 2.9 2 1 0 2 2 2 0 Xylanase inhibitor N-terminal Glyco_transf_8 PF01501.20 KXL51058.1 - 2.9e-09 36.9 0.2 4.8e-09 36.2 0.2 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 KXL51058.1 - 0.0038 17.2 0.2 0.0069 16.4 0.2 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.8 KXL51058.1 - 0.034 13.5 0.1 0.059 12.7 0.1 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Abhydrolase_6 PF12697.7 KXL51059.1 - 5.5e-05 23.9 0.3 0.00015 22.5 0.3 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family NMO PF03060.15 KXL51060.1 - 7.2e-18 65.0 0.1 1.1e-17 64.4 0.1 1.3 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KXL51060.1 - 7.9e-05 21.8 0.0 7.9e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain SH3_9 PF14604.6 KXL51061.1 - 1.4e-09 37.6 0.2 7.8e-09 35.3 0.2 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KXL51061.1 - 1.2e-08 34.5 0.1 2.9e-08 33.3 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXL51061.1 - 4.7e-08 32.5 2.2 7.6e-08 31.8 0.2 2.4 3 0 0 3 3 3 1 SH3 domain CHAP PF05257.16 KXL51061.1 - 0.14 12.7 0.0 0.34 11.5 0.0 1.6 1 0 0 1 1 1 0 CHAP domain RPAP2_Rtr1 PF04181.13 KXL51062.1 - 1.4e-13 50.9 0.4 6.6e-13 48.8 0.4 2.1 1 1 0 1 1 1 1 Rtr1/RPAP2 family Pterin_bind PF00809.22 KXL51063.1 - 6.4e-75 252.0 0.1 9.2e-75 251.5 0.1 1.2 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 KXL51063.1 - 1.8e-37 128.3 0.0 3.6e-37 127.3 0.0 1.5 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) DUF1098 PF06497.11 KXL51063.1 - 0.079 13.4 0.1 6.1 7.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1098) A_deaminase PF00962.22 KXL51064.1 - 1.8e-10 40.7 0.0 1.7e-09 37.5 0.0 2.0 1 1 0 1 1 1 1 Adenosine/AMP deaminase Zn_clus PF00172.18 KXL51065.1 - 9.1e-07 28.9 11.8 1.6e-06 28.2 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXL51067.1 - 6.6e-16 58.1 0.6 1.1e-15 57.4 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL51067.1 - 7.3e-10 38.8 10.8 1.5e-09 37.9 10.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclase PF04199.13 KXL51068.1 - 1.9e-14 54.0 0.2 2.9e-14 53.5 0.2 1.4 1 0 0 1 1 1 1 Putative cyclase Kelch_4 PF13418.6 KXL51069.1 - 2.4e-17 62.6 0.1 8.9e-07 28.8 0.0 4.9 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KXL51069.1 - 2.1e-16 59.7 2.8 2.8e-09 37.0 0.0 5.2 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 KXL51069.1 - 1.2e-14 53.6 0.4 0.00026 20.5 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 KXL51069.1 - 2.6e-12 46.4 1.2 0.00031 20.6 0.0 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 KXL51069.1 - 1.2e-10 41.3 1.2 0.036 14.4 0.0 4.7 3 1 1 4 4 4 3 Kelch motif Kelch_2 PF07646.15 KXL51069.1 - 4.5e-08 32.8 0.2 0.0059 16.5 0.0 4.1 4 0 0 4 4 4 2 Kelch motif BTB PF00651.31 KXL51069.1 - 0.0043 17.3 0.0 0.0086 16.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain ANAPC4_WD40 PF12894.7 KXL51070.1 - 0.0096 16.2 0.0 0.78 10.1 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXL51070.1 - 0.02 15.8 0.0 0.49 11.4 0.0 2.9 3 0 0 3 3 3 0 WD domain, G-beta repeat Cupin_8 PF13621.6 KXL51071.1 - 6.2e-40 137.5 0.0 1.1e-39 136.7 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.14 KXL51071.1 - 5.7e-12 46.0 0.0 5.7e-08 32.9 0.0 2.3 1 1 1 2 2 2 2 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 KXL51071.1 - 1.2e-09 38.0 8.7 0.015 15.3 0.0 5.7 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KXL51071.1 - 9.6e-08 31.9 0.1 9.1e-05 22.4 0.0 3.4 4 1 0 4 4 4 2 Kelch motif Cupin_4 PF08007.12 KXL51071.1 - 4.9e-07 29.5 0.0 8.7e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 KXL51071.1 - 0.14 12.6 0.0 0.37 11.2 0.0 1.6 1 0 0 1 1 1 0 JmjC domain, hydroxylase Kelch_3 PF13415.6 KXL51071.1 - 1.3 9.4 8.0 3.7 7.9 0.1 4.9 6 0 0 6 6 6 0 Galactose oxidase, central domain DSPc PF00782.20 KXL51072.1 - 6.3e-31 107.0 0.0 7.3e-22 77.6 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXL51072.1 - 4.1e-05 23.3 0.0 0.0012 18.5 0.0 2.3 2 0 0 2 2 2 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 KXL51072.1 - 0.11 12.2 0.6 11 5.6 0.0 2.6 2 1 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) GATase PF00117.28 KXL51073.1 - 5.8e-10 39.2 0.0 8.2e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 KXL51073.1 - 0.025 14.2 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain GDA1_CD39 PF01150.17 KXL51074.1 - 1.4e-109 366.6 0.0 1.9e-109 366.2 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Glyco_hydro_72 PF03198.14 KXL51075.1 - 2.9e-113 378.3 0.2 3.6e-113 378.0 0.2 1.1 1 0 0 1 1 1 1 Glucanosyltransferase 2-oxoacid_dh PF00198.23 KXL51076.1 - 0.06 12.8 0.0 0.071 12.5 0.0 1.0 1 0 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) S4 PF01479.25 KXL51077.1 - 2.4e-12 46.4 0.9 2.4e-12 46.4 0.9 2.4 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 KXL51077.1 - 7.4e-06 26.8 0.8 1.1e-05 26.2 0.2 1.7 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Uds1 PF15456.6 KXL51077.1 - 0.057 13.6 0.4 1.8 8.8 0.0 2.2 2 0 0 2 2 2 0 Up-regulated During Septation Ribosomal_L21e PF01157.18 KXL51078.1 - 7e-46 154.2 4.5 1e-45 153.7 3.7 1.6 2 0 0 2 2 2 1 Ribosomal protein L21e DUF3987 PF13148.6 KXL51078.1 - 0.023 13.7 0.5 0.028 13.4 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF5486 PF17588.2 KXL51078.1 - 0.024 14.5 0.7 0.054 13.4 0.7 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5486) LRS4 PF10422.9 KXL51078.1 - 0.053 13.1 0.0 0.064 12.8 0.0 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 DUF4023 PF13215.6 KXL51078.1 - 0.13 12.3 0.8 0.25 11.4 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4023) Atg29_N PF18388.1 KXL51079.1 - 1.1e-25 89.1 0.7 2.1e-25 88.3 0.7 1.5 1 0 0 1 1 1 1 Atg29 N-terminal domain DUF4939 PF16297.5 KXL51081.1 - 0.0058 16.5 0.0 0.0074 16.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) DUF543 PF04418.12 KXL51082.1 - 0.5 10.4 2.9 0.66 10.0 2.3 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF543) Vps23_core PF09454.10 KXL51083.1 - 7.4e-21 73.9 1.8 1.2e-20 73.2 0.1 2.2 2 1 1 3 3 3 1 Vps23 core domain Paralemmin PF03285.15 KXL51083.1 - 0.0045 16.6 0.0 0.0071 16.0 0.0 1.2 1 0 0 1 1 1 1 Paralemmin HAUS-augmin3 PF14932.6 KXL51083.1 - 0.0051 16.4 3.6 0.0068 16.0 3.6 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 Enkurin PF13864.6 KXL51083.1 - 0.032 14.7 1.2 0.066 13.6 1.2 1.5 1 0 0 1 1 1 0 Calmodulin-binding FlgT_N PF16548.5 KXL51083.1 - 0.077 13.6 4.2 0.14 12.8 4.2 1.4 1 0 0 1 1 1 0 Flagellar assembly protein T, N-terminal domain Snapin_Pallidin PF14712.6 KXL51083.1 - 0.27 11.7 8.5 0.51 10.8 8.2 1.5 1 1 0 1 1 1 0 Snapin/Pallidin DUF3450 PF11932.8 KXL51083.1 - 1.1 8.5 8.8 1.6 7.9 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) KfrA_N PF11740.8 KXL51083.1 - 3.2 8.5 14.2 6.4 7.5 9.4 2.2 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term CytochromB561_N PF09786.9 KXL51084.1 - 1.8 7.5 11.6 2.1 7.2 11.6 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal DSBA PF01323.20 KXL51085.1 - 6e-23 81.6 0.0 6.7e-23 81.5 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain BAR PF03114.18 KXL51086.1 - 1.9e-62 211.0 7.5 2.4e-62 210.7 7.5 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KXL51086.1 - 8.7e-15 54.1 0.0 1.6e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXL51086.1 - 1.6e-11 43.9 0.1 3e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXL51086.1 - 2.1e-09 36.9 0.0 5.4e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain DUF2220 PF09983.9 KXL51086.1 - 0.18 11.2 1.4 0.39 10.1 1.4 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) APG6_N PF17675.1 KXL51086.1 - 0.39 11.3 13.1 3.1 8.3 7.3 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region TMPIT PF07851.13 KXL51086.1 - 9 5.4 9.8 8.2 5.6 0.3 2.1 1 1 1 2 2 2 0 TMPIT-like protein T2SSI PF02501.17 KXL51087.1 - 0.95 9.7 4.7 12 6.1 0.2 3.2 2 2 2 4 4 4 0 Type II secretion system (T2SS), protein I Aldo_ket_red PF00248.21 KXL51089.1 - 8.7e-15 54.7 0.0 1.3e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Clat_adaptor_s PF01217.20 KXL51090.1 - 6.6e-53 178.5 1.2 7.9e-53 178.2 1.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PulA_N1 PF17999.1 KXL51090.1 - 0.088 13.6 0.3 0.18 12.6 0.2 1.6 1 1 0 1 1 1 0 Pullulanase N1-terminal domain Maf1 PF09174.10 KXL51091.1 - 4.2e-57 193.1 0.0 5.8e-57 192.6 0.0 1.2 1 0 0 1 1 1 1 Maf1 regulator GAF_2 PF13185.6 KXL51092.1 - 1.3e-13 51.5 0.0 3.6e-13 50.0 0.0 1.7 1 1 0 1 1 1 1 GAF domain GAF PF01590.26 KXL51092.1 - 1.3e-07 32.3 0.0 1.8e-07 31.9 0.0 1.2 1 1 0 1 1 1 1 GAF domain TnsE_C PF18623.1 KXL51092.1 - 0.086 12.8 0.0 0.18 11.7 0.0 1.4 2 0 0 2 2 2 0 TnsE C-terminal domain MRP PF09387.10 KXL51096.1 - 0.15 12.1 0.2 0.33 10.9 0.1 1.6 2 0 0 2 2 2 0 Mitochondrial RNA binding protein MRP DUF3306 PF11748.8 KXL51096.1 - 0.79 10.6 3.4 0.36 11.7 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) AhpC-TSA_2 PF13911.6 KXL51097.1 - 1.7e-18 66.8 0.0 2.7e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KXL51097.1 - 0.00098 19.0 0.0 0.0019 18.1 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family MFS_1 PF07690.16 KXL51098.1 - 2.8e-38 131.7 49.3 1.3e-37 129.6 49.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL51098.1 - 2e-11 43.4 27.7 4e-08 32.5 2.5 3.4 3 1 1 4 4 4 3 Sugar (and other) transporter Glyoxalase PF00903.25 KXL51099.1 - 1.3e-09 38.3 1.5 6.8e-08 32.8 1.7 2.6 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KXL51099.1 - 0.048 13.9 0.3 0.51 10.6 0.1 2.5 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Zip PF02535.22 KXL51100.1 - 1.2e-55 189.1 5.1 2e-54 185.1 5.1 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter DUF445 PF04286.12 KXL51100.1 - 0.41 10.4 0.7 0.63 9.8 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Sen15 PF09631.10 KXL51103.1 - 4.2e-25 87.9 0.0 1.1e-23 83.4 0.0 2.2 1 1 0 1 1 1 1 Sen15 protein DUF716 PF04819.12 KXL51104.1 - 0.033 13.8 0.1 0.049 13.3 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF716) SLAC1 PF03595.17 KXL51105.1 - 4.5e-63 213.5 50.3 5.1e-63 213.3 50.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel GFO_IDH_MocA PF01408.22 KXL51106.1 - 1.9e-09 38.4 0.4 5.2e-09 37.0 0.4 1.9 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold AMP-binding PF00501.28 KXL51106.1 - 0.031 12.9 0.0 0.053 12.1 0.0 1.3 1 1 0 1 1 1 0 AMP-binding enzyme DHDPS PF00701.22 KXL51107.1 - 1.3e-34 119.3 0.0 1.6e-34 118.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Oxidored_FMN PF00724.20 KXL51110.1 - 5e-53 180.5 0.0 2.2e-51 175.1 0.0 2.3 2 1 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family RNA_pol_Rpo13 PF12136.8 KXL51110.1 - 0.056 13.4 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain IF3_N PF05198.16 KXL51110.1 - 0.16 12.3 0.0 1.4 9.2 0.0 2.3 2 0 0 2 2 2 0 Translation initiation factor IF-3, N-terminal domain ERG4_ERG24 PF01222.17 KXL51111.1 - 4e-165 549.8 1.3 4.8e-165 549.5 1.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KXL51111.1 - 0.0015 18.1 2.9 0.0023 17.5 1.6 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) DUF2985 PF11204.8 KXL51112.1 - 7.7e-37 125.3 1.2 7.7e-37 125.3 1.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) Aldo_ket_red PF00248.21 KXL51113.1 - 8.3e-45 153.2 0.0 1.2e-42 146.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family CENP-S PF15630.6 KXL51114.1 - 9.9e-29 99.6 0.0 1.2e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KXL51114.1 - 3.2e-07 30.4 0.0 3.6e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold ADH_N PF08240.12 KXL51115.1 - 5.6e-27 93.8 0.1 1.1e-26 92.8 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXL51115.1 - 4e-21 75.4 0.2 8e-21 74.4 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXL51115.1 - 7.8e-10 38.6 0.3 9.3e-05 22.0 0.0 2.4 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KXL51115.1 - 0.00027 22.0 0.0 0.00055 21.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXL51115.1 - 0.0025 17.1 0.3 0.0044 16.3 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KXL51115.1 - 0.0073 15.9 0.9 0.055 13.0 0.2 2.1 1 1 1 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_2 PF00890.24 KXL51115.1 - 0.022 13.8 0.4 0.04 13.0 0.2 1.5 1 1 0 1 1 1 0 FAD binding domain Methyltransf_25 PF13649.6 KXL51115.1 - 0.044 14.5 0.3 1.3 9.7 0.2 2.4 2 0 0 2 2 2 0 Methyltransferase domain 3HCDH_N PF02737.18 KXL51115.1 - 0.099 12.5 0.3 0.18 11.7 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 KXL51116.1 - 2.7e-56 190.8 0.1 3.3e-56 190.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL51116.1 - 2.3e-52 177.3 0.1 3e-52 176.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL51116.1 - 1.5e-11 44.6 0.3 2.1e-11 44.1 0.3 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL51116.1 - 9.2e-07 28.6 0.0 1.1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXL51116.1 - 0.022 14.2 0.3 0.035 13.5 0.1 1.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KXL51116.1 - 0.042 13.4 0.2 0.067 12.7 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family THF_DHG_CYH_C PF02882.19 KXL51116.1 - 0.075 12.3 0.0 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.15 KXL51116.1 - 0.095 11.8 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KXL51116.1 - 0.2 10.7 0.1 0.38 9.8 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain Glyco_transf_5 PF08323.11 KXL51116.1 - 0.2 11.3 0.0 1.5 8.5 0.0 2.0 2 1 0 2 2 2 0 Starch synthase catalytic domain MIOX PF05153.15 KXL51117.1 - 2.3e-122 407.4 0.6 2.3e-122 407.4 0.6 1.3 2 0 0 2 2 2 1 Myo-inositol oxygenase DUF1796 PF08795.10 KXL51117.1 - 0.014 15.3 0.3 0.022 14.7 0.3 1.3 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) HD PF01966.22 KXL51117.1 - 0.065 13.5 0.0 2.1 8.6 0.0 2.4 2 0 0 2 2 2 0 HD domain Cytochrom_C_2 PF01322.20 KXL51117.1 - 0.091 13.7 2.4 0.11 13.4 1.2 1.8 2 0 0 2 2 2 0 Cytochrome C' UBD PF16455.5 KXL51117.1 - 0.1 12.8 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-binding domain RFX1_trans_act PF04589.13 KXL51119.1 - 0.11 12.7 0.1 0.13 12.4 0.1 1.1 1 0 0 1 1 1 0 RFX1 transcription activation region His_Phos_1 PF00300.22 KXL51120.1 - 1.1e-28 100.3 0.1 3.8e-27 95.3 0.1 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) tRNA-synt_1 PF00133.22 KXL51121.1 - 4.3e-35 121.0 0.0 4.7e-25 87.9 0.0 2.8 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KXL51121.1 - 1.1e-15 57.4 0.0 3e-10 39.4 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KXL51121.1 - 4.1e-09 36.6 0.0 1.1e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KXL51121.1 - 1e-06 28.3 0.0 2.2e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain ARL6IP6 PF15062.6 KXL51122.1 - 0.025 14.7 0.1 0.044 13.9 0.0 1.5 1 1 0 1 1 1 0 Haemopoietic lineage transmembrane helix Fungal_trans_2 PF11951.8 KXL51123.1 - 6.8e-13 48.2 0.1 1.2e-12 47.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL51123.1 - 7e-09 35.7 9.1 1.4e-08 34.7 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GFO_IDH_MocA PF01408.22 KXL51124.1 - 6.1e-14 52.9 0.5 1.6e-12 48.3 0.4 2.2 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXL51124.1 - 5.8e-09 36.0 0.0 1.1e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain HSF_DNA-bind PF00447.17 KXL51125.1 - 2.6e-26 92.1 0.5 4e-26 91.4 0.5 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding F-box-like PF12937.7 KXL51126.1 - 8.1e-08 32.0 0.0 9.7e-07 28.6 0.0 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXL51126.1 - 2.5e-06 27.2 0.0 6.9e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 F-box domain IR1-M PF12185.8 KXL51126.1 - 0.24 11.4 0.0 0.41 10.6 0.0 1.3 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain Lum_binding PF00677.17 KXL51128.1 - 2.9e-46 155.4 3.4 2.1e-23 82.1 1.0 2.2 2 0 0 2 2 2 2 Lumazine binding domain CoA_transf_3 PF02515.17 KXL51129.1 - 7.2e-123 410.3 0.0 8.1e-123 410.2 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III FOXP-CC PF16159.5 KXL51131.1 - 0.27 11.9 1.7 0.5 11.0 0.5 2.1 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 KXL51131.1 - 0.4 11.2 0.2 0.4 11.2 0.2 1.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF1682 PF07946.14 KXL51131.1 - 2.4 7.3 8.3 3.1 6.9 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) adh_short_C2 PF13561.6 KXL51132.1 - 1.4e-50 172.0 0.0 1.7e-50 171.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL51132.1 - 2.7e-45 154.2 0.0 3.5e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL51132.1 - 4.1e-07 30.1 0.0 6.9e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL51132.1 - 0.00031 20.3 0.1 0.00066 19.2 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KXL51132.1 - 0.0014 18.0 0.0 0.002 17.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.18 KXL51132.1 - 0.092 12.6 0.0 0.26 11.2 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 KXL51132.1 - 0.17 11.3 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Glyco_hydro_72 PF03198.14 KXL51133.1 - 3.5e-129 430.6 3.9 4.2e-129 430.3 3.9 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KXL51133.1 - 0.0017 17.9 0.1 0.042 13.3 0.1 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Sporozoite_P67 PF05642.11 KXL51133.1 - 2.8 5.9 8.7 4 5.4 8.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PAP1 PF08601.10 KXL51133.1 - 5.9 6.5 9.5 11 5.6 9.5 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 FGGY_C PF02782.16 KXL51135.1 - 3e-49 167.5 0.2 5.4e-49 166.6 0.2 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KXL51135.1 - 1.6e-23 83.5 0.9 6.3e-20 71.8 0.1 3.1 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KXL51135.1 - 0.00023 20.8 0.1 0.0013 18.3 0.0 2.1 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family FMN_dh PF01070.18 KXL51136.1 - 1.2e-122 409.3 0.0 1.4e-122 409.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KXL51136.1 - 1.3e-22 79.7 0.1 2.6e-22 78.7 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KXL51136.1 - 4.2e-08 32.7 0.0 7.8e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KXL51136.1 - 2.7e-05 23.4 0.4 0.00022 20.4 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KXL51136.1 - 0.0015 18.0 0.1 0.0026 17.2 0.1 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 KXL51136.1 - 0.0066 15.9 1.4 0.21 11.0 0.1 2.3 1 1 0 2 2 2 1 Histidine biosynthesis protein G3P_antiterm PF04309.12 KXL51136.1 - 0.081 12.3 0.0 5.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator ThiG PF05690.14 KXL51136.1 - 0.12 11.7 0.1 2.5 7.4 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Pro_CA PF00484.19 KXL51136.1 - 0.15 12.4 0.1 0.56 10.5 0.0 1.9 2 0 0 2 2 2 0 Carbonic anhydrase AAA PF00004.29 KXL51137.1 - 4.1e-62 208.4 0.1 3.2e-41 140.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXL51137.1 - 1.2e-12 47.4 0.4 5.3e-08 32.5 0.1 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KXL51137.1 - 1.1e-10 42.1 6.1 0.012 16.0 0.0 5.1 2 2 2 5 5 5 3 AAA ATPase domain AAA_5 PF07728.14 KXL51137.1 - 2.4e-09 37.3 0.1 0.00041 20.4 0.0 3.4 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXL51137.1 - 1.2e-07 32.0 2.1 0.041 14.2 0.1 4.2 2 2 2 4 4 4 2 AAA domain AAA_2 PF07724.14 KXL51137.1 - 2.1e-05 24.7 0.0 0.00066 19.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Vps4_C PF09336.10 KXL51137.1 - 3e-05 23.9 0.5 0.28 11.2 0.0 3.7 4 0 0 4 4 3 2 Vps4 C terminal oligomerisation domain AAA_14 PF13173.6 KXL51137.1 - 5.3e-05 23.2 0.0 0.14 12.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KXL51137.1 - 6.2e-05 23.0 0.4 0.069 13.1 0.5 3.9 3 1 0 3 3 3 1 NACHT domain AAA_7 PF12775.7 KXL51137.1 - 6.7e-05 22.5 0.0 0.21 11.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region RNA_helicase PF00910.22 KXL51137.1 - 0.00023 21.5 0.0 0.24 11.8 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 KXL51137.1 - 0.00035 20.8 0.0 0.036 14.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KXL51137.1 - 0.00053 19.2 0.0 0.15 11.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 KXL51137.1 - 0.00061 19.2 0.1 0.44 9.9 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KXL51137.1 - 0.0015 18.4 0.0 0.27 11.1 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXL51137.1 - 0.0016 18.2 0.0 0.17 11.6 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KXL51137.1 - 0.0018 17.5 0.0 0.0087 15.3 0.0 2.1 3 0 0 3 3 3 1 TIP49 P-loop domain AAA_28 PF13521.6 KXL51137.1 - 0.0025 18.1 0.0 0.41 10.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 KXL51137.1 - 0.004 16.6 0.0 8.6 5.7 0.0 3.7 2 2 2 4 4 4 0 Bacterial TniB protein Rad17 PF03215.15 KXL51137.1 - 0.0048 16.9 0.6 0.39 10.6 0.0 3.1 2 2 1 3 3 3 1 Rad17 P-loop domain ATPase_2 PF01637.18 KXL51137.1 - 0.018 15.0 0.0 15 5.4 0.0 3.4 2 2 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 KXL51137.1 - 0.018 14.6 2.2 4.7 6.7 0.1 3.4 3 2 1 4 4 3 0 AAA domain DAP3 PF10236.9 KXL51137.1 - 0.027 13.7 0.0 1.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_18 PF13238.6 KXL51137.1 - 0.043 14.4 0.0 0.69 10.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KXL51137.1 - 0.046 13.5 0.1 2.3 7.9 0.0 3.1 3 1 1 4 4 4 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KXL51137.1 - 0.085 12.6 0.3 2.7 7.7 0.1 2.6 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KXL51137.1 - 0.1 12.3 0.0 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KXL51137.1 - 0.15 11.8 0.0 19 4.9 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Pkinase PF00069.25 KXL51139.1 - 1.7e-65 221.0 0.0 2.2e-65 220.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL51139.1 - 1.7e-29 102.9 0.0 2.4e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXL51139.1 - 0.027 13.8 0.0 0.31 10.3 0.0 2.3 2 1 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 KXL51139.1 - 0.039 12.7 0.0 0.064 12.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_C PF00433.24 KXL51139.1 - 0.43 11.3 3.9 1.4 9.6 3.9 2.0 1 1 0 1 1 1 0 Protein kinase C terminal domain Glyco_hydro_47 PF01532.20 KXL51140.1 - 2.4e-134 448.7 0.0 2.7e-134 448.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DHquinase_I PF01487.15 KXL51141.1 - 8.8e-22 78.5 0.0 1.4e-21 77.8 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 KXL51141.1 - 4.1e-18 65.4 0.0 8.5e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.22 KXL51141.1 - 2.9e-10 40.5 0.0 5.3e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase SDH_C PF18317.1 KXL51141.1 - 1.4e-08 34.4 0.1 3.6e-08 33.0 0.0 1.8 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KXL51141.1 - 1.3e-05 25.2 0.1 3.6e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase UPF0231 PF06062.11 KXL51141.1 - 0.11 12.8 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0231) AAA_16 PF13191.6 KXL51141.1 - 0.14 12.6 0.0 0.35 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Fungal_trans PF04082.18 KXL51142.1 - 7.8e-12 44.8 0.5 1.1e-11 44.3 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL51142.1 - 2.8e-06 27.4 14.5 5.9e-06 26.3 14.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AP_endonuc_2 PF01261.24 KXL51143.1 - 1.1e-33 116.5 0.1 1.5e-33 116.0 0.1 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel GFO_IDH_MocA PF01408.22 KXL51144.1 - 3.6e-26 92.3 0.0 6.5e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXL51144.1 - 1.8e-07 31.2 0.0 3.4e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Pex24p PF06398.11 KXL51145.1 - 4.5e-85 285.8 6.9 5.3e-85 285.6 6.9 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin GerA PF03323.13 KXL51145.1 - 0.13 10.6 0.7 0.21 10.0 0.7 1.2 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein Pam16 PF03656.13 KXL51146.1 - 1.9e-34 118.4 0.9 2.3e-34 118.1 0.9 1.1 1 0 0 1 1 1 1 Pam16 Ada_Zn_binding PF02805.16 KXL51148.1 - 1.3e-28 98.8 8.6 2.1e-28 98.1 8.6 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 KXL51148.1 - 3.8e-09 36.4 0.0 7.5e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 KXL51148.1 - 2.3e-06 27.8 0.0 4.6e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Glycophorin_A PF01102.18 KXL51149.1 - 0.062 13.6 0.4 0.084 13.1 0.4 1.3 1 0 0 1 1 1 0 Glycophorin A HTH_32 PF13565.6 KXL51150.1 - 1.3e-06 28.9 0.8 0.012 16.2 0.0 3.2 3 1 1 4 4 4 2 Homeodomain-like domain HTH_7 PF02796.15 KXL51150.1 - 0.00012 22.0 0.0 0.00053 20.0 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 KXL51150.1 - 0.029 14.4 0.0 0.068 13.2 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix HTH_23 PF13384.6 KXL51150.1 - 0.062 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain PAX PF00292.18 KXL51150.1 - 0.16 11.9 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 'Paired box' domain DHquinase_II PF01220.19 KXL51151.1 - 1.2e-61 206.4 0.0 1.4e-61 206.2 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Dioxygenase_C PF00775.21 KXL51152.1 - 1.2e-38 132.4 0.0 1.5e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KXL51152.1 - 4.7e-31 106.5 0.0 7.8e-31 105.8 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus Inositol_P PF00459.25 KXL51155.1 - 1.5e-76 257.5 0.0 1.7e-76 257.3 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Shikimate_dh_N PF08501.11 KXL51156.1 - 1.8e-23 82.6 0.0 7.8e-23 80.5 0.0 2.1 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KXL51156.1 - 8.9e-05 22.2 0.0 0.00026 20.7 0.0 1.8 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KXL51156.1 - 0.078 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase OCD_Mu_crystall PF02423.15 KXL51156.1 - 0.099 11.6 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Sugar_tr PF00083.24 KXL51157.1 - 2.1e-136 455.4 25.9 2.4e-136 455.2 25.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL51157.1 - 6.9e-23 81.1 35.7 6.9e-23 81.1 35.7 2.3 1 1 2 3 3 3 1 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 KXL51157.1 - 0.054 14.0 1.2 0.45 11.1 1.2 2.3 2 0 0 2 2 2 0 Phage holin family 2 DUF2516 PF10724.9 KXL51157.1 - 3.2 8.1 6.2 0.46 10.8 0.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2516) XPG_I_2 PF12813.7 KXL51158.1 - 1.9e-34 119.2 0.0 2.8e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing CtnDOT_TraJ PF07863.11 KXL51158.1 - 0.0042 17.7 0.0 0.013 16.1 0.0 1.8 1 0 0 1 1 1 1 Homologues of TraJ from Bacteroides conjugative transposon HMG_box PF00505.19 KXL51159.1 - 2.1e-21 76.1 2.7 2.3e-21 76.0 2.7 1.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXL51159.1 - 9.2e-14 51.8 1.9 9.9e-14 51.7 1.9 1.0 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.6 KXL51159.1 - 0.0021 18.0 1.3 0.0024 17.8 1.3 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box 5 RSN1_7TM PF02714.15 KXL51160.1 - 4e-73 246.1 20.4 4e-73 246.1 20.4 1.5 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KXL51160.1 - 1e-41 142.3 0.7 2.6e-41 141.0 0.7 1.8 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KXL51160.1 - 5.6e-41 140.7 0.1 8.3e-41 140.1 0.1 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Homoserine_dh PF00742.19 KXL51161.1 - 6.6e-50 169.4 0.0 1e-49 168.8 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KXL51161.1 - 1.3e-15 58.1 0.0 2.3e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain CC2-LZ PF16516.5 KXL51161.1 - 0.12 12.7 0.0 0.45 10.9 0.0 1.8 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator AAA_22 PF13401.6 KXL51161.1 - 0.13 12.5 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF4078 PF13300.6 KXL51162.1 - 3.4e-27 94.6 14.6 3.4e-27 94.6 14.6 3.7 4 1 0 4 4 4 1 Domain of unknown function (DUF4078) Cwf_Cwc_15 PF04889.12 KXL51162.1 - 2.1 8.0 33.2 0.11 12.2 17.6 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein TB2_DP1_HVA22 PF03134.19 KXL51163.1 - 3.3e-20 71.8 8.7 5.5e-20 71.1 8.7 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family TANGO2 PF05742.12 KXL51164.1 - 1.5e-71 241.4 0.0 1.7e-71 241.2 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 zf-C2H2_jaz PF12171.8 KXL51165.1 - 6.3e-05 23.1 1.0 0.0001 22.5 1.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXL51165.1 - 0.0095 16.3 0.1 0.016 15.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF1691 PF07950.11 KXL51166.1 - 4.4e-34 117.4 2.4 2.8e-29 102.0 1.5 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Bud13 PF09736.9 KXL51167.1 - 3.5e-49 166.9 15.3 3.5e-49 166.9 15.3 2.7 3 1 1 4 4 4 1 Pre-mRNA-splicing factor of RES complex DNA_binding_1 PF01035.20 KXL51168.1 - 2.6e-23 81.9 0.1 3.5e-23 81.5 0.1 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain adh_short_C2 PF13561.6 KXL51171.1 - 2.8e-47 161.2 0.0 3.5e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL51171.1 - 1.5e-40 138.7 0.0 1.9e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL51171.1 - 6.1e-12 45.8 0.1 9.7e-12 45.2 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXL51171.1 - 0.00058 19.4 0.0 0.001 18.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXL51171.1 - 0.0013 17.8 0.0 0.0027 16.8 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXL51171.1 - 0.0023 17.4 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KXL51171.1 - 0.0087 15.2 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DFP PF04127.15 KXL51171.1 - 0.052 13.4 0.3 0.14 12.0 0.3 1.6 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein FAD_binding_3 PF01494.19 KXL51172.1 - 1.4e-19 70.6 0.0 2.1e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 KXL51172.1 - 6.2e-05 22.2 0.0 8.7e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_9 PF13454.6 KXL51172.1 - 0.083 12.9 0.5 0.8 9.7 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXL51172.1 - 0.11 12.8 1.2 0.2 11.9 0.1 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GFO_IDH_MocA PF01408.22 KXL51173.1 - 7.8e-17 62.2 0.1 1.1e-16 61.7 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KXL51173.1 - 0.043 14.5 0.0 0.072 13.7 0.0 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Acetyltransf_3 PF13302.7 KXL51174.1 - 4.7e-18 66.2 0.0 6.3e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXL51174.1 - 4.2e-12 46.3 0.0 5.9e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KXL51174.1 - 5e-09 36.5 0.0 8.7e-09 35.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXL51174.1 - 6.1e-06 26.6 0.0 8.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KXL51174.1 - 0.00062 19.5 0.0 0.00073 19.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXL51174.1 - 0.016 15.1 0.0 0.024 14.5 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXL51174.1 - 0.05 13.6 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Vps52 PF04129.12 KXL51177.1 - 1.2e-122 410.3 0.0 1.5e-122 409.9 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 KXL51177.1 - 2.7e-05 22.8 0.2 4e-05 22.2 0.2 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec3 CCDC144C PF14915.6 KXL51177.1 - 0.014 14.5 0.1 0.024 13.8 0.1 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Sipho_Gp157 PF05565.11 KXL51177.1 - 0.044 13.8 3.3 0.26 11.3 0.8 2.4 2 0 0 2 2 2 0 Siphovirus Gp157 GRDP-like PF07173.12 KXL51177.1 - 0.08 13.6 0.5 0.28 11.8 0.2 2.0 1 1 1 2 2 2 0 Glycine-rich domain-containing protein-like COG2 PF06148.11 KXL51177.1 - 0.098 12.7 1.0 1.3 9.1 0.1 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4795 PF16043.5 KXL51177.1 - 0.21 11.2 1.0 0.4 10.2 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) TBCC_N PF16752.5 KXL51177.1 - 0.24 11.9 5.7 4 7.9 0.9 3.7 4 1 0 4 4 4 0 Tubulin-specific chaperone C N-terminal domain eIF-5a PF01287.20 KXL51178.1 - 9.8e-30 102.5 0.9 1.4e-29 102.0 0.9 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 KXL51178.1 - 0.0058 16.6 0.0 0.0093 16.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain zf-RRN7 PF11781.8 KXL51179.1 - 0.00023 20.8 2.7 0.00046 19.8 2.7 1.5 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 GPS2_interact PF15784.5 KXL51181.1 - 0.0062 16.9 0.4 0.0097 16.3 0.4 1.3 1 0 0 1 1 1 1 G-protein pathway suppressor 2-interacting domain PTPLA PF04387.14 KXL51183.1 - 7.2e-59 198.2 11.5 1.1e-58 197.6 11.5 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA UreD PF01774.17 KXL51184.1 - 5.4e-47 160.5 0.0 6.3e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein DUF390 PF04094.14 KXL51184.1 - 0.0066 14.8 0.1 0.0077 14.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF390) STAG PF08514.11 KXL51185.1 - 5.1e-33 113.4 2.6 8e-33 112.7 0.1 2.7 2 0 0 2 2 2 1 STAG domain Cep57_MT_bd PF06657.13 KXL51185.1 - 0.032 14.7 0.5 0.18 12.3 0.5 2.3 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Muted PF14942.6 KXL51185.1 - 4.9 7.5 10.2 20 5.5 0.6 2.8 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Pectate_lyase_3 PF12708.7 KXL51186.1 - 2.5e-05 24.2 0.0 2.9e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Pectate lyase superfamily protein Sugar_tr PF00083.24 KXL51188.1 - 2.2e-39 135.6 16.9 3.3e-39 135.0 16.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL51188.1 - 1.4e-16 60.4 29.0 1.4e-16 60.4 29.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily 2TM PF13239.6 KXL51188.1 - 9 6.7 11.4 12 6.3 0.3 3.5 3 0 0 3 3 3 0 2TM domain Gag_MA PF01140.19 KXL51189.1 - 0.068 12.9 0.2 0.11 12.2 0.2 1.6 1 1 0 1 1 1 0 Matrix protein (MA), p15 AAA PF00004.29 KXL51191.1 - 3.6e-40 137.5 0.0 7e-40 136.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KXL51191.1 - 1.5e-19 69.7 0.3 3e-19 68.7 0.3 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KXL51191.1 - 4.2e-09 36.1 0.0 9.3e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KXL51191.1 - 0.00014 21.9 0.5 0.00067 19.7 0.1 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXL51191.1 - 0.00019 21.8 1.6 0.02 15.3 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KXL51191.1 - 0.00026 20.8 0.0 0.0007 19.4 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain JIP_LZII PF16471.5 KXL51191.1 - 0.00059 20.0 2.1 0.0018 18.4 2.1 1.8 1 0 0 1 1 1 1 JNK-interacting protein leucine zipper II AAA_2 PF07724.14 KXL51191.1 - 0.0015 18.7 0.0 0.011 15.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KXL51191.1 - 0.002 18.4 1.7 0.077 13.3 0.0 2.9 2 1 1 3 3 3 1 AAA domain PhoH PF02562.16 KXL51191.1 - 0.0032 16.9 0.2 0.077 12.4 0.1 2.4 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 KXL51191.1 - 0.007 15.8 0.1 0.019 14.3 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KXL51191.1 - 0.011 15.9 0.0 0.031 14.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KXL51191.1 - 0.013 14.7 0.0 0.032 13.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 KXL51191.1 - 0.075 12.8 0.1 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 KXL51191.1 - 0.13 11.7 0.0 0.36 10.3 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 KXL51191.1 - 0.4 10.4 0.0 0.4 10.4 0.0 2.8 2 2 0 2 2 2 0 AAA domain TauD PF02668.16 KXL51192.1 - 1.5e-26 93.8 0.0 2.3e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KXL51192.1 - 1.2e-07 32.3 0.1 2.8e-07 31.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) Pkinase PF00069.25 KXL51193.1 - 3.3e-70 236.5 0.0 4.4e-70 236.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL51193.1 - 1.6e-32 112.8 0.0 2.4e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KXL51193.1 - 7.5e-13 49.0 0.4 3.3e-12 46.9 0.4 2.2 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 KXL51193.1 - 1.6e-08 34.8 0.1 9.6e-08 32.3 0.0 2.3 3 0 0 3 3 3 1 C2 domain Kinase-like PF14531.6 KXL51193.1 - 1.6e-08 34.2 0.1 1e-07 31.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KXL51193.1 - 0.00051 19.1 0.2 0.0011 18.0 0.2 1.4 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KXL51193.1 - 0.0025 17.5 0.1 0.66 9.6 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KXL51193.1 - 0.003 17.5 0.0 0.0054 16.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXL51193.1 - 0.044 13.3 0.6 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.14 KXL51193.1 - 0.051 12.9 0.1 0.089 12.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pro-kuma_activ PF09286.11 KXL51194.1 - 1.1e-44 152.2 0.0 1.8e-44 151.5 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain ADH_N PF08240.12 KXL51195.1 - 8.6e-17 61.0 0.2 1.3e-16 60.5 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXL51195.1 - 2.3e-15 56.7 0.0 4.3e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Rho_N PF07498.12 KXL51195.1 - 0.023 14.6 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain AlaDh_PNT_C PF01262.21 KXL51195.1 - 0.11 11.8 0.3 0.16 11.3 0.3 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KXL51195.1 - 0.12 12.0 0.2 0.23 11.0 0.2 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF2647 PF10839.8 KXL51197.1 - 0.11 12.6 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2647) PfkB PF00294.24 KXL51199.1 - 1.2e-54 185.7 0.6 1.3e-54 185.5 0.6 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase RE_R_Pab1 PF09522.10 KXL51199.1 - 0.17 12.0 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 R.Pab1 restriction endonuclease Ada_Zn_binding PF02805.16 KXL51200.1 - 1.8e-30 104.7 5.0 2.7e-30 104.2 5.0 1.2 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 KXL51200.1 - 2.1e-07 30.8 0.0 4.8e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 KXL51200.1 - 6.7e-05 23.1 0.4 0.00013 22.2 0.4 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Transposase_20 PF02371.16 KXL51200.1 - 0.055 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family GFA PF04828.14 KXL51202.1 - 3.7e-06 27.2 1.1 3.7e-06 27.2 1.1 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme WDCP PF15390.6 KXL51202.1 - 0.13 10.6 0.5 0.16 10.4 0.5 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family zf-CCHC_4 PF14392.6 KXL51202.1 - 9.9 6.0 10.9 1.4 8.7 3.5 2.6 2 0 0 2 2 2 0 Zinc knuckle HET PF06985.11 KXL51203.1 - 4.9e-09 36.7 10.6 5e-09 36.7 6.9 2.5 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) ODV-E18 PF10717.9 KXL51204.1 - 0.0057 16.5 0.6 0.0075 16.1 0.6 1.2 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 DUF929 PF06053.11 KXL51204.1 - 0.057 12.7 0.5 0.064 12.6 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF929) Baculo_11_kDa PF06143.11 KXL51204.1 - 0.06 12.9 3.7 0.09 12.4 3.7 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF4834 PF16118.5 KXL51204.1 - 0.071 14.1 0.8 0.11 13.5 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) 7TM_GPCR_Srh PF10318.9 KXL51204.1 - 0.084 11.9 4.7 0.11 11.5 4.7 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh EphA2_TM PF14575.6 KXL51204.1 - 0.085 13.8 1.5 0.1 13.5 1.5 1.4 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 KXL51204.1 - 0.21 11.5 1.7 0.26 11.2 1.7 1.1 1 0 0 1 1 1 0 TMEM154 protein family HCMVantigenic_N PF12154.8 KXL51204.1 - 1.3 9.1 4.2 2.9 8.1 4.0 1.5 2 0 0 2 2 2 0 Glycoprotein B N-terminal antigenic domain of HCMV RCR PF12273.8 KXL51204.1 - 5.7 7.6 5.2 8.2 7.1 5.2 1.5 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red HEM4 PF02602.15 KXL51205.1 - 0.0066 15.8 0.0 0.26 10.6 0.0 2.2 1 1 0 2 2 2 1 Uroporphyrinogen-III synthase HemD TPR_7 PF13176.6 KXL51205.1 - 0.021 14.8 0.0 0.074 13.1 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXL51205.1 - 0.096 12.9 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-C2H2_11 PF16622.5 KXL51206.1 - 0.012 15.4 1.8 0.047 13.5 0.0 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-CCCH_2 PF14608.6 KXL51206.1 - 0.014 15.8 2.7 0.054 14.0 0.4 3.3 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-BED PF02892.15 KXL51206.1 - 0.4 10.7 7.1 24 5.1 0.0 4.7 4 1 0 4 4 4 0 BED zinc finger zf-C2H2_4 PF13894.6 KXL51206.1 - 2.5 9.2 0.0 2.5 9.2 0.0 5.7 6 0 0 6 6 6 0 C2H2-type zinc finger Opy2 PF09463.10 KXL51206.1 - 3 8.2 5.9 2.3 8.6 0.6 3.1 2 0 0 2 2 2 0 Opy2 protein DBD_Tnp_Mut PF03108.15 KXL51206.1 - 3.5 7.7 5.6 21 5.2 0.5 3.1 3 0 0 3 3 3 0 MuDR family transposase Aminotran_1_2 PF00155.21 KXL51207.1 - 1.1e-07 31.3 0.0 2.3e-07 30.3 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II LCCL PF03815.19 KXL51208.1 - 2.2e-20 72.6 0.1 3.5e-20 71.9 0.1 1.3 1 0 0 1 1 1 1 LCCL domain HsbA PF12296.8 KXL51209.1 - 5.9e-17 62.2 0.0 1.2e-16 61.3 0.0 1.5 2 0 0 2 2 2 1 Hydrophobic surface binding protein A Acetyltransf_1 PF00583.25 KXL51210.1 - 7.2e-13 48.8 0.0 1e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXL51210.1 - 7.3e-13 48.6 0.0 6.8e-12 45.4 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXL51210.1 - 1.5e-10 41.3 0.0 3.6e-10 40.1 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXL51210.1 - 1.2e-05 25.4 0.1 0.00068 19.7 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXL51210.1 - 0.056 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein BCS1_N PF08740.11 KXL51211.1 - 1.2e-40 139.5 1.5 2.5e-40 138.5 0.7 1.7 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 KXL51211.1 - 1.6e-17 64.2 0.0 8.5e-17 61.8 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KXL51211.1 - 0.014 14.7 0.0 0.074 12.4 0.0 2.2 2 0 0 2 2 2 0 KaiC RuvB_N PF05496.12 KXL51211.1 - 0.015 15.0 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXL51211.1 - 0.02 15.3 0.2 0.052 13.9 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KXL51211.1 - 0.11 12.6 0.3 0.42 10.8 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KXL51211.1 - 0.27 11.0 2.4 0.95 9.2 2.4 2.0 1 1 0 1 1 1 0 AAA domain DUF572 PF04502.13 KXL51212.1 - 7e-71 239.6 13.4 8.3e-71 239.3 13.4 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF951 PF06107.11 KXL51212.1 - 0.079 12.9 0.4 4.6 7.2 0.0 2.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF951) E6 PF00518.17 KXL51212.1 - 0.1 13.0 0.8 6.7 7.2 0.7 2.4 1 1 1 2 2 2 0 Early Protein (E6) DNA_RNApol_7kD PF03604.13 KXL51212.1 - 0.1 12.3 1.7 11 5.8 0.2 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_12 PF11331.8 KXL51212.1 - 0.19 11.6 0.3 18 5.3 0.0 2.3 2 0 0 2 2 2 0 Probable zinc-ribbon domain zf-ACC PF17848.1 KXL51212.1 - 0.34 11.0 2.5 2.8 8.1 0.5 2.4 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain CAF1 PF04857.20 KXL51212.1 - 0.42 9.7 3.0 0.63 9.2 3.0 1.2 1 0 0 1 1 1 0 CAF1 family ribonuclease TF_Zn_Ribbon PF08271.12 KXL51212.1 - 3.8 7.1 5.3 15 5.2 1.2 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding TPR_2 PF07719.17 KXL51213.1 - 1.7e-22 77.6 26.8 0.00043 20.2 0.0 10.8 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_1 PF00515.28 KXL51213.1 - 4.3e-20 70.6 8.7 0.0017 18.1 0.0 7.9 8 1 0 8 8 8 5 Tetratricopeptide repeat ANAPC3 PF12895.7 KXL51213.1 - 4.2e-18 65.3 19.3 2.3e-15 56.6 1.3 5.5 4 2 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KXL51213.1 - 7.3e-17 61.6 30.5 0.00042 20.8 0.0 8.0 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 KXL51213.1 - 7.9e-13 48.8 38.3 0.041 14.5 6.2 7.4 5 2 3 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 KXL51213.1 - 5.2e-12 45.0 1.9 0.18 12.1 0.3 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXL51213.1 - 7.2e-11 42.0 43.3 0.1 13.5 1.4 11.2 7 3 5 12 12 12 5 Tetratricopeptide repeat TPR_12 PF13424.6 KXL51213.1 - 2.3e-09 37.4 37.6 0.005 17.1 0.9 8.8 6 3 2 9 9 9 5 Tetratricopeptide repeat TPR_6 PF13174.6 KXL51213.1 - 9.8e-08 32.2 10.6 2.2 9.1 0.3 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXL51213.1 - 3e-07 30.0 8.0 2.6 7.8 0.0 7.0 8 0 0 8 8 8 3 TPR repeat TPR_7 PF13176.6 KXL51213.1 - 1.2e-05 25.0 16.6 0.17 12.0 0.0 7.6 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXL51213.1 - 0.018 14.9 0.2 0.018 14.9 0.2 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat PPR PF01535.20 KXL51213.1 - 0.19 12.0 2.8 2.2 8.7 0.0 3.8 5 0 0 5 5 5 0 PPR repeat TPR_20 PF14561.6 KXL51213.1 - 0.51 10.7 15.1 0.81 10.1 0.3 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat Glyco_transf_15 PF01793.16 KXL51214.1 - 1.5e-114 382.7 8.5 1.8e-114 382.4 8.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase CoaE PF01121.20 KXL51215.1 - 1.3e-41 142.2 0.0 5.8e-41 140.1 0.0 1.8 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.6 KXL51215.1 - 0.0047 17.1 0.0 0.061 13.5 0.0 2.4 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 KXL51215.1 - 0.11 12.6 0.0 0.73 9.9 0.0 2.2 2 1 0 2 2 2 0 Shikimate kinase VirB7 PF17413.2 KXL51216.1 - 0.017 14.4 0.0 0.041 13.2 0.0 1.6 1 0 0 1 1 1 0 Outer membrane lipoprotein virB7 FAT PF02259.23 KXL51217.1 - 7e-70 235.9 12.2 5.4e-69 233.0 8.9 2.4 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 KXL51217.1 - 2.3e-29 102.9 1.6 3.2e-29 102.5 0.1 2.0 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KXL51217.1 - 1.5e-08 34.3 2.7 3.2e-08 33.2 0.3 2.6 2 0 0 2 2 2 1 FATC domain Thymidylat_synt PF00303.19 KXL51217.1 - 0.016 14.3 1.1 0.034 13.3 1.1 1.5 1 0 0 1 1 1 0 Thymidylate synthase TPR_1 PF00515.28 KXL51217.1 - 0.078 12.8 1.1 4.5 7.2 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat HRDC PF00570.23 KXL51217.1 - 0.2 11.6 1.1 0.6 10.1 0.1 2.3 2 0 0 2 2 2 0 HRDC domain TPR_2 PF07719.17 KXL51217.1 - 1.4 9.2 5.3 12 6.3 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat GCP_N_terminal PF17681.1 KXL51218.1 - 2.8e-25 89.6 0.0 2.8e-25 89.6 0.0 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KXL51218.1 - 6.7e-13 48.8 1.7 6.7e-13 48.8 1.7 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal Pkinase PF00069.25 KXL51219.1 - 6.2e-65 219.2 0.0 9.7e-65 218.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL51219.1 - 1.4e-36 126.1 0.0 2.1e-31 109.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KXL51219.1 - 1.2e-06 28.1 0.0 0.0025 17.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KXL51219.1 - 0.002 18.1 0.0 0.0043 17.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KXL51219.1 - 0.0072 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KXL51219.1 - 0.012 14.6 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KXL51219.1 - 0.023 14.1 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXL51219.1 - 0.27 10.0 1.5 0.63 8.8 1.5 1.7 1 1 0 1 1 1 0 Fungal protein kinase Ras PF00071.22 KXL51220.1 - 2.5e-49 167.0 0.0 3.1e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXL51220.1 - 8.8e-30 103.4 0.1 2.3e-29 102.1 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXL51220.1 - 2.1e-10 40.3 0.0 2.8e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXL51220.1 - 0.00032 20.8 0.0 0.0006 19.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 KXL51220.1 - 0.00048 20.5 0.1 0.0026 18.1 0.1 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 KXL51220.1 - 0.0015 17.9 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.12 KXL51220.1 - 0.019 14.5 0.1 0.035 13.6 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.20 KXL51220.1 - 0.022 13.9 2.4 1 8.4 0.1 2.6 2 1 1 3 3 3 0 G-protein alpha subunit RsgA_GTPase PF03193.16 KXL51220.1 - 0.025 14.5 0.2 7.9 6.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 KXL51220.1 - 0.032 13.7 0.1 0.061 12.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KXL51220.1 - 0.064 13.0 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KXL51220.1 - 0.081 12.9 0.1 0.19 11.7 0.1 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KXL51220.1 - 0.11 12.7 0.6 0.23 11.6 0.2 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KXL51220.1 - 0.13 12.7 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 KXL51220.1 - 0.19 11.0 0.6 0.27 10.5 0.1 1.5 2 0 0 2 2 2 0 Septin Strep_SA_rep PF06696.11 KXL51220.1 - 0.4 10.7 4.9 0.74 9.9 4.9 1.4 1 0 0 1 1 1 0 Streptococcal surface antigen repeat Aldedh PF00171.22 KXL51221.1 - 2.1e-145 484.8 0.0 2.6e-145 484.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Peptidase_M99_C PF17129.4 KXL51222.1 - 0.034 14.3 0.1 0.072 13.3 0.1 1.5 1 0 0 1 1 1 0 C-terminal domain of metallo-carboxypeptidase adh_short PF00106.25 KXL51223.1 - 1e-27 96.9 0.0 3.1e-22 79.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXL51223.1 - 4.2e-15 56.0 0.0 5.4e-14 52.3 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KXL51223.1 - 4.5e-06 26.3 0.2 1.8e-05 24.3 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXL51223.1 - 7.9e-05 22.6 0.4 0.00023 21.1 0.4 1.9 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KXL51223.1 - 0.0025 17.3 0.3 0.021 14.2 0.3 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Mur_ligase PF01225.25 KXL51223.1 - 0.095 13.0 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, catalytic domain Baculo_F PF12259.8 KXL51224.1 - 0.026 13.1 0.0 0.036 12.6 0.0 1.1 1 0 0 1 1 1 0 Baculovirus F protein Dimer_Tnp_hAT PF05699.14 KXL51226.1 - 3e-18 65.4 0.0 4.9e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DcpS_C PF11969.8 KXL51226.1 - 0.093 13.2 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding Smg4_UPF3 PF03467.15 KXL51227.1 - 2.3e-33 115.6 0.4 2.3e-33 115.6 0.4 2.7 2 1 0 2 2 2 1 Smg-4/UPF3 family RRM_1 PF00076.22 KXL51227.1 - 0.0045 16.8 0.0 0.015 15.1 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET PF00856.28 KXL51227.1 - 0.15 12.5 2.4 0.24 11.8 2.4 1.5 1 0 0 1 1 1 0 SET domain CDC45 PF02724.14 KXL51227.1 - 0.83 7.9 10.6 1 7.6 10.6 1.2 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 KXL51227.1 - 3.7 7.2 7.8 14 5.3 8.1 1.9 2 0 0 2 2 2 0 FAM176 family Pmp3 PF01679.17 KXL51228.1 - 5.6e-11 42.5 6.0 7e-11 42.2 6.0 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Putative_PNPOx PF01243.20 KXL51229.1 - 0.0013 18.9 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Mito_carr PF00153.27 KXL51230.1 - 2.1e-59 197.4 5.8 4.5e-22 77.8 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein bZIP_1 PF00170.21 KXL51231.1 - 0.0013 18.8 9.6 0.0024 17.9 9.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXL51231.1 - 1.1 9.4 12.0 2 8.5 12.0 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Sugar_tr PF00083.24 KXL51232.1 - 7.7e-88 295.3 21.8 9.5e-88 295.0 21.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL51232.1 - 1.9e-10 40.2 43.9 5.1e-06 25.7 12.1 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily GP24_25 PF17388.2 KXL51232.1 - 0.2 11.6 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 Tail assembly gene products 24 & 25 MFMR PF07777.11 KXL51233.1 - 0.035 14.6 0.4 0.035 14.6 0.4 3.7 2 2 2 4 4 4 0 G-box binding protein MFMR ALG11_N PF15924.5 KXL51235.1 - 6.8e-81 271.3 0.0 1.2e-80 270.5 0.0 1.3 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KXL51235.1 - 1.2e-18 67.3 0.0 2.2e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXL51235.1 - 1.7e-09 38.2 0.0 2.9e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXL51235.1 - 8.6e-05 22.6 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Peptidase_S10 PF00450.22 KXL51236.1 - 7e-115 384.8 0.0 9.1e-115 384.4 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase GRA6 PF05084.13 KXL51236.1 - 0.27 11.2 3.6 0.42 10.5 0.5 2.1 1 1 1 2 2 2 0 Granule antigen protein (GRA6) Rad52_Rad22 PF04098.15 KXL51237.1 - 1.4e-62 210.2 0.1 2.1e-62 209.6 0.1 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein AreA_N PF07573.11 KXL51237.1 - 0.03 15.0 4.2 1.7 9.3 0.6 2.9 2 0 0 2 2 2 0 Nitrogen regulatory protein AreA N terminus RPAP1_N PF08621.10 KXL51237.1 - 0.037 13.8 0.0 0.08 12.7 0.0 1.6 1 0 0 1 1 1 0 RPAP1-like, N-terminal Yae1_N PF09811.9 KXL51238.1 - 1.7e-09 37.2 4.4 2.5e-09 36.7 4.4 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal tRNA-synt_1g PF09334.11 KXL51239.1 - 1.2e-151 504.9 0.0 1.5e-151 504.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KXL51239.1 - 6.5e-09 34.6 0.1 3.5e-06 25.5 0.0 3.3 2 2 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) Tad_C PF09977.9 KXL51239.1 - 0.11 13.8 1.7 0.23 12.7 1.7 1.5 1 0 0 1 1 1 0 Putative Tad-like Flp pilus-assembly zf-C2H2 PF00096.26 KXL51240.1 - 8.8e-12 44.8 18.1 0.00012 22.4 7.8 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXL51240.1 - 8.9e-12 44.9 12.1 1.5e-07 31.5 0.2 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXL51240.1 - 3.2e-08 33.7 15.2 0.0067 17.2 6.3 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXL51240.1 - 6.2e-08 32.4 18.1 2.4e-05 24.2 4.0 4.7 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXL51240.1 - 1.6e-05 25.0 4.3 0.27 11.6 2.3 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXL51240.1 - 0.00012 22.3 5.3 0.038 14.4 3.1 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type SUIM_assoc PF16619.5 KXL51240.1 - 0.0044 17.1 1.1 0.016 15.3 1.1 2.0 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 zf-Di19 PF05605.12 KXL51240.1 - 0.094 13.0 3.5 0.19 12.1 3.5 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_recom PF13408.6 KXL51240.1 - 0.79 10.3 8.0 0.07 13.7 1.9 2.2 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain FYVE PF01363.21 KXL51240.1 - 1.1 9.5 8.7 2.6 8.3 8.7 1.7 1 1 0 1 1 1 0 FYVE zinc finger zf-UBP PF02148.19 KXL51240.1 - 2.8 8.3 6.1 7.9 6.9 6.1 1.8 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-C2H2_11 PF16622.5 KXL51240.1 - 6.4 6.6 11.3 13 5.6 0.1 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-BED PF02892.15 KXL51240.1 - 9.8 6.3 8.2 1.3e+03 -0.5 8.1 2.5 1 1 0 1 1 1 0 BED zinc finger C2 PF00168.30 KXL51241.1 - 9.6e-40 135.0 0.0 4.2e-19 68.8 0.0 2.4 2 0 0 2 2 2 2 C2 domain EF-hand_1 PF00036.32 KXL51241.1 - 0.00035 19.9 0.2 0.0012 18.3 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KXL51241.1 - 0.007 16.2 0.1 0.034 14.1 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 KXL51241.1 - 0.018 14.6 0.0 0.043 13.3 0.0 1.7 1 0 0 1 1 1 0 EF hand PGA2 PF07543.12 KXL51241.1 - 0.35 10.8 1.5 0.73 9.8 1.5 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 Dishevelled PF02377.15 KXL51241.1 - 5.3 7.5 12.8 0.52 10.8 0.1 2.9 3 0 0 3 3 3 0 Dishevelled specific domain Coatomer_E PF04733.14 KXL51243.1 - 1.4e-34 119.9 0.0 1.6e-34 119.7 0.0 1.1 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 KXL51243.1 - 2.1e-05 25.0 11.6 0.0089 16.5 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat DHBP_synthase PF00926.19 KXL51243.1 - 0.012 15.1 0.3 0.02 14.4 0.3 1.3 1 0 0 1 1 1 0 3,4-dihydroxy-2-butanone 4-phosphate synthase ANAPC3 PF12895.7 KXL51243.1 - 0.037 14.3 4.4 6.9 7.0 0.0 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Use1 PF09753.9 KXL51244.1 - 1.8e-07 31.2 1.2 3.2e-07 30.3 1.2 1.6 1 1 0 1 1 1 1 Membrane fusion protein Use1 BSP_II PF05432.11 KXL51244.1 - 1.2e-05 25.2 4.4 1.6e-05 24.8 4.4 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) YliH PF10799.8 KXL51244.1 - 0.018 15.0 0.5 0.042 13.8 0.1 1.8 2 0 0 2 2 2 0 Biofilm formation protein (YliH/bssR) DUF4611 PF15387.6 KXL51244.1 - 0.075 13.3 3.1 0.17 12.1 3.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) RNase_H2_suC PF08615.11 KXL51244.1 - 0.13 12.5 0.8 0.24 11.6 0.6 1.4 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Synaptobrevin PF00957.21 KXL51244.1 - 0.25 11.2 0.2 0.65 9.8 0.0 1.8 2 0 0 2 2 2 0 Synaptobrevin DUF4530 PF15039.6 KXL51244.1 - 0.49 10.5 9.5 0.27 11.4 7.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4530) APG6_N PF17675.1 KXL51244.1 - 2.5 8.6 12.9 2.9 8.4 9.3 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region Radial_spoke PF04712.12 KXL51244.1 - 3.2 6.6 10.0 0.86 8.5 6.9 1.5 2 0 0 2 2 2 0 Radial spokehead-like protein DUF4637 PF15470.6 KXL51244.1 - 4.7 6.9 9.4 15 5.3 6.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) DUF4395 PF14340.6 KXL51246.1 - 0.13 12.6 5.0 0.044 14.1 1.4 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4395) MmgE_PrpD PF03972.14 KXL51247.1 - 4.5e-101 338.6 0.5 5e-101 338.4 0.5 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Kdo PF06293.14 KXL51248.1 - 3e-06 26.7 0.0 1.6e-05 24.4 0.0 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KXL51248.1 - 3.4e-06 26.6 0.0 4e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KXL51248.1 - 1.6e-05 25.0 0.0 0.033 14.1 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXL51248.1 - 0.035 12.9 0.0 0.047 12.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 KXL51248.1 - 0.14 11.4 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine kinase EcKinase PF02958.20 KXL51248.1 - 0.15 11.3 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase RIO1 PF01163.22 KXL51248.1 - 0.23 11.0 0.0 0.53 9.9 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.25 KXL51249.1 - 5.1e-56 189.9 0.0 7.3e-56 189.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL51249.1 - 3.6e-22 78.9 0.0 5.5e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXL51249.1 - 0.00041 19.8 0.0 0.0011 18.3 0.0 1.7 1 1 0 1 1 1 1 Kinase-like FMN_dh PF01070.18 KXL51250.1 - 5.1e-113 377.7 0.0 6.2e-113 377.4 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KXL51250.1 - 8.1e-18 64.3 0.0 1.6e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KXL51250.1 - 0.00033 19.9 0.0 0.00057 19.1 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KXL51250.1 - 0.014 14.4 0.0 0.027 13.5 0.0 1.6 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KXL51250.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase bZIP_2 PF07716.15 KXL51251.1 - 1.1e-13 51.0 14.1 2.6e-13 49.8 14.1 1.6 1 0 0 1 1 1 1 Basic region leucine zipper XhlA PF10779.9 KXL51251.1 - 0.0041 17.3 2.7 0.0092 16.2 2.7 1.5 1 0 0 1 1 1 1 Haemolysin XhlA bZIP_1 PF00170.21 KXL51251.1 - 0.018 15.1 12.5 0.018 15.1 12.5 2.6 2 1 0 2 2 2 0 bZIP transcription factor SOGA PF11365.8 KXL51251.1 - 0.054 14.6 4.4 0.054 14.6 4.4 1.9 2 0 0 2 2 2 0 Protein SOGA TFIIA PF03153.13 KXL51251.1 - 0.66 9.9 20.6 0.97 9.4 20.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LCD1 PF09798.9 KXL51251.1 - 1.6 7.1 8.2 2.6 6.4 8.2 1.3 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF737 PF05300.11 KXL51251.1 - 5 7.4 19.3 4.6 7.6 18.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF737) Cut8 PF08559.10 KXL51253.1 - 5.4e-78 261.9 0.0 6.8e-78 261.6 0.0 1.0 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein p450 PF00067.22 KXL51254.1 - 6.9e-66 222.9 0.0 9e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3984 PF13136.6 KXL51255.1 - 3.1e-36 125.4 18.0 1.7e-31 109.9 14.3 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF3984) DUF3727 PF12527.8 KXL51255.1 - 0.11 12.7 0.4 0.58 10.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3727) Dynamin_N PF00350.23 KXL51256.1 - 4.4e-34 118.0 0.1 1.1e-33 116.6 0.1 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KXL51256.1 - 5.9e-30 104.5 3.0 5.5e-29 101.3 0.5 2.9 2 1 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 KXL51256.1 - 7.2e-05 22.8 0.1 0.00047 20.2 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 KXL51256.1 - 0.017 14.9 0.4 0.047 13.4 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_16 PF13191.6 KXL51256.1 - 0.026 14.9 1.9 1.6 9.1 0.0 3.1 4 0 0 4 4 4 0 AAA ATPase domain AAA_29 PF13555.6 KXL51256.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mem_trans PF03547.18 KXL51258.1 - 1.1e-46 159.0 2.8 2e-27 95.6 0.0 2.0 2 0 0 2 2 2 2 Membrane transport protein zf-CCHC_3 PF13917.6 KXL51259.1 - 0.012 15.6 0.1 0.016 15.2 0.1 1.3 1 0 0 1 1 1 0 Zinc knuckle Acetyltransf_3 PF13302.7 KXL51260.1 - 9.5e-14 52.2 0.0 1.5e-13 51.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXL51260.1 - 3.6e-12 46.5 0.0 5e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXL51260.1 - 3.2e-06 27.5 0.0 4.1e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KXL51260.1 - 2.6e-05 24.4 0.0 3.1e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXL51260.1 - 0.00048 20.1 0.1 0.0007 19.5 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KXL51260.1 - 0.0016 18.4 0.0 0.0021 18.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KXL51260.1 - 0.0027 17.4 0.0 0.0044 16.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Zn_clus PF00172.18 KXL51262.1 - 4.7e-09 36.2 11.3 7.1e-09 35.7 11.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PS_Dcarbxylase PF02666.15 KXL51263.1 - 1.5e-53 181.3 0.0 1.9e-53 181.0 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase DUF1754 PF08555.10 KXL51264.1 - 3.1e-16 60.0 4.0 3.7e-16 59.7 4.0 1.1 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) Phage_GPD PF05954.11 KXL51264.1 - 0.035 13.4 0.1 0.038 13.3 0.1 1.1 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) adh_short PF00106.25 KXL51265.1 - 3.2e-32 111.6 0.1 4.1e-32 111.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXL51265.1 - 1.5e-25 90.2 0.1 2e-25 89.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KXL51265.1 - 2.6e-06 27.1 0.1 4.7e-06 26.2 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 KXL51265.1 - 0.012 15.5 0.1 0.1 12.4 0.0 2.0 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein RmlD_sub_bind PF04321.17 KXL51265.1 - 0.15 11.2 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Amidase PF01425.21 KXL51266.1 - 2.4e-36 125.7 0.1 4.8e-36 124.7 0.1 1.5 1 1 0 1 1 1 1 Amidase PI-PLC-X PF00388.19 KXL51267.1 - 4.2e-59 198.3 0.0 2.3e-58 195.9 0.0 2.2 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KXL51267.1 - 6.1e-38 129.7 0.1 1.4e-37 128.6 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_1 PF00036.32 KXL51267.1 - 3e-05 23.2 0.1 0.012 15.2 0.0 3.5 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 KXL51267.1 - 0.00013 22.4 0.5 0.0026 18.2 0.0 2.6 1 1 1 2 2 2 1 EF-hand domain pair C2 PF00168.30 KXL51267.1 - 0.00062 20.0 0.0 0.0037 17.5 0.0 2.3 1 1 0 1 1 1 1 C2 domain EF-hand_5 PF13202.6 KXL51267.1 - 0.0022 17.4 0.2 0.035 13.6 0.0 3.0 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 KXL51267.1 - 0.016 15.0 0.1 0.19 11.6 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 KXL51267.1 - 0.034 14.1 0.4 2.7 8.2 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain EF-hand_10 PF14788.6 KXL51267.1 - 0.064 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 EF hand STE2 PF02116.15 KXL51268.1 - 1.4e-70 237.9 20.2 1.6e-70 237.6 20.2 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR NDUF_B4 PF07225.12 KXL51268.1 - 0.043 13.7 0.7 0.085 12.8 0.1 1.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) HhH-GPD PF00730.25 KXL51269.1 - 2.7e-20 72.8 0.0 5.3e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KXL51269.1 - 3.6e-08 32.9 0.0 1.1e-07 31.3 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif SURNod19 PF07712.12 KXL51270.1 - 0.0027 16.5 0.0 0.013 14.2 0.0 1.8 2 0 0 2 2 2 1 Stress up-regulated Nod 19 Asp PF00026.23 KXL51272.1 - 1.3e-11 44.5 0.0 2.3e-11 43.7 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease SKG6 PF08693.10 KXL51272.1 - 4.4e-06 26.0 5.1 9.6e-06 24.9 5.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.6 KXL51272.1 - 0.0048 17.7 0.0 0.0096 16.8 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Podoplanin PF05808.11 KXL51272.1 - 0.011 15.9 0.2 0.019 15.1 0.2 1.4 1 0 0 1 1 1 0 Podoplanin DUF4381 PF14316.6 KXL51272.1 - 0.015 15.6 0.0 0.027 14.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) PTP_tm PF18861.1 KXL51272.1 - 0.073 13.1 1.5 0.17 11.9 1.2 1.7 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J LapA_dom PF06305.11 KXL51272.1 - 0.13 12.1 0.9 0.26 11.1 0.9 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Adeno_E3_CR2 PF02439.15 KXL51272.1 - 0.15 11.8 0.2 0.28 11.0 0.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 VSP PF03302.13 KXL51272.1 - 0.19 10.5 0.3 0.28 10.0 0.3 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Ribosomal_L22e PF01776.17 KXL51273.1 - 4.7e-42 142.8 0.0 5.8e-42 142.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF1160 PF06648.11 KXL51273.1 - 0.13 12.3 0.0 0.17 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) AA_permease_2 PF13520.6 KXL51274.1 - 1.4e-55 188.9 50.6 1.7e-55 188.6 50.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXL51274.1 - 1.3e-18 66.9 41.3 1.7e-18 66.5 41.3 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.16 KXL51275.1 - 1.6e-40 139.1 29.9 1.6e-40 139.1 29.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXL51275.1 - 6.4e-08 31.5 1.4 1.1e-07 30.7 1.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2982 PF11201.8 KXL51275.1 - 0.23 11.0 0.0 0.38 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2982) zf-C2H2 PF00096.26 KXL51277.1 - 0.087 13.3 2.8 1.3 9.6 0.1 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type TBCC_N PF16752.5 KXL51277.1 - 0.41 11.1 3.4 0.84 10.1 3.4 1.4 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain zf-C2H2_4 PF13894.6 KXL51277.1 - 5.2 8.2 9.9 12 7.0 1.0 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger DUF5122 PF17164.4 KXL51278.1 - 0.31 11.4 2.4 2.3 8.6 2.4 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5122) beta-propeller GSHPx PF00255.19 KXL51280.1 - 4.7e-40 135.5 0.1 6.1e-40 135.2 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KXL51280.1 - 0.0013 18.6 0.0 0.0034 17.3 0.0 1.8 2 1 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 KXL51280.1 - 0.064 13.0 0.0 0.11 12.2 0.0 1.5 2 0 0 2 2 2 0 Redoxin Methyltransf_25 PF13649.6 KXL51281.1 - 5.1e-07 30.3 0.0 1.1e-06 29.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL51281.1 - 0.00014 22.5 0.0 0.00024 21.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL51281.1 - 0.00014 22.5 0.0 0.00024 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL51281.1 - 0.0007 19.4 0.0 0.0023 17.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Spermine_synth PF01564.17 KXL51282.1 - 1.5e-76 256.0 0.0 2.7e-76 255.2 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KXL51282.1 - 3.1e-25 87.8 0.1 5.2e-25 87.1 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 KXL51282.1 - 5.4e-05 23.8 0.0 0.00011 22.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL51282.1 - 0.0015 18.4 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXL51282.1 - 0.0025 18.5 0.4 0.011 16.4 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain DUF43 PF01861.16 KXL51282.1 - 0.0079 15.4 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain Methyltransf_18 PF12847.7 KXL51282.1 - 0.18 11.7 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Pmp3 PF01679.17 KXL51283.1 - 1.2e-22 79.8 8.2 1.4e-22 79.6 8.2 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator ThrE PF06738.12 KXL51284.1 - 9.8e-69 231.4 14.0 1.1e-66 224.6 0.7 2.6 3 0 0 3 3 3 2 Putative threonine/serine exporter Wbp11 PF09429.10 KXL51284.1 - 0.068 13.6 3.6 0.15 12.5 3.6 1.5 1 0 0 1 1 1 0 WW domain binding protein 11 UPF0016 PF01169.19 KXL51284.1 - 2.1 8.7 7.0 0.2 12.0 0.3 2.8 2 1 0 2 2 2 0 Uncharacterized protein family UPF0016 NAD_kinase PF01513.21 KXL51285.1 - 3.9e-77 259.3 0.0 5.3e-77 258.9 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase CsbD PF05532.12 KXL51286.1 - 1.3e-13 50.6 24.9 6.8e-11 41.9 6.4 3.1 2 1 1 3 3 3 3 CsbD-like Apo-CIII PF05778.12 KXL51286.1 - 0.069 12.8 0.5 0.16 11.6 0.5 1.7 1 1 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) Rick_17kDa_Anti PF05433.15 KXL51286.1 - 5.5 6.9 18.6 0.96 9.4 2.3 4.2 4 0 0 4 4 4 0 Glycine zipper 2TM domain Fungal_trans PF04082.18 KXL51287.1 - 1e-28 100.1 0.0 1.7e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL51287.1 - 6.3e-09 35.8 14.8 6.3e-09 35.8 14.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Trimer_CC PF08954.11 KXL51287.1 - 0.22 11.1 1.1 0.6 9.7 1.1 1.8 1 0 0 1 1 1 0 Trimerisation motif DSPn PF14671.6 KXL51289.1 - 4.3e-42 143.9 0.0 1.9e-39 135.3 0.0 2.8 2 1 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KXL51289.1 - 5e-16 58.7 0.0 9.1e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXL51289.1 - 1e-05 25.2 0.0 1.7e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 KXL51289.1 - 0.017 14.8 0.1 0.032 13.9 0.1 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) polyprenyl_synt PF00348.17 KXL51291.1 - 9.7e-63 211.6 0.0 2.1e-62 210.5 0.0 1.5 1 1 0 1 1 1 1 Polyprenyl synthetase Ribosomal_L7Ae PF01248.26 KXL51292.1 - 1e-21 76.4 0.1 3.1e-21 74.9 0.1 1.8 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF4575 PF15143.6 KXL51292.1 - 0.21 11.8 1.5 3.9 7.7 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4575) Amidohydro_2 PF04909.14 KXL51293.1 - 2.4e-23 83.3 0.0 2.8e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase PIG-F PF06699.11 KXL51294.1 - 1.1e-65 221.1 7.6 1.3e-65 220.9 7.6 1.0 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F RDD PF06271.12 KXL51294.1 - 0.14 12.3 4.2 2 8.6 0.1 2.4 2 0 0 2 2 2 0 RDD family Romo1 PF10247.9 KXL51294.1 - 0.16 12.4 8.7 0.49 10.8 2.1 2.3 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Gly-zipper_Omp PF13488.6 KXL51294.1 - 1.7 8.7 5.3 14 5.7 0.4 2.2 2 0 0 2 2 2 0 Glycine zipper TraL PF07178.11 KXL51294.1 - 8.1 7.0 11.7 7.2 7.2 0.3 3.7 3 1 1 4 4 4 0 TraL protein zf-Tim10_DDP PF02953.15 KXL51295.1 - 4.8e-21 74.2 4.7 6.7e-21 73.7 4.7 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3811 PF11656.8 KXL51295.1 - 0.048 14.0 0.2 0.081 13.3 0.2 1.4 1 0 0 1 1 1 0 YjbD family (DUF3811) DUF842 PF05811.13 KXL51295.1 - 0.055 13.2 5.6 0.74 9.5 5.5 2.1 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) RhoGAP PF00620.27 KXL51297.1 - 2.3e-37 128.1 0.0 3.6e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain DUF3074 PF11274.8 KXL51300.1 - 1.4e-54 184.9 0.0 1.8e-54 184.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) START PF01852.19 KXL51300.1 - 0.00014 21.3 0.0 0.0012 18.3 0.0 2.3 1 1 0 1 1 1 1 START domain Sugar_tr PF00083.24 KXL51301.1 - 1.3e-107 360.5 31.1 1.8e-107 360.0 31.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL51301.1 - 1.2e-23 83.7 50.6 3.6e-17 62.3 18.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NUDE_C PF04880.13 KXL51302.1 - 8 6.9 10.1 5.1 7.5 6.0 2.3 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region Chalcone_2 PF16035.5 KXL51303.1 - 5.2e-68 228.9 0.0 8.2e-68 228.2 0.0 1.3 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 KXL51303.1 - 4.2e-05 23.7 0.0 0.00013 22.1 0.0 1.8 1 0 0 1 1 1 1 Chalcone isomerase-like Pkinase PF00069.25 KXL51304.1 - 1.2e-45 155.9 0.0 5.5e-45 153.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL51304.1 - 1.3e-26 93.4 0.0 1.9e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXL51304.1 - 0.0053 15.6 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXL51304.1 - 0.043 13.1 0.0 3.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 KXL51304.1 - 0.063 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HET PF06985.11 KXL51305.1 - 6.5e-33 114.1 1.3 1.2e-32 113.3 0.1 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Zn_clus PF00172.18 KXL51306.1 - 2.2e-10 40.4 11.6 4.5e-10 39.5 11.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXL51306.1 - 0.00068 18.7 0.0 0.0022 17.1 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain SYS1 PF09801.9 KXL51306.1 - 0.076 13.2 0.1 0.25 11.5 0.1 1.8 1 0 0 1 1 1 0 Integral membrane protein S linking to the trans Golgi network Acetyltransf_1 PF00583.25 KXL51307.1 - 3.2e-10 40.3 0.0 8e-10 39.0 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXL51307.1 - 1.1e-08 35.0 0.0 1.8e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXL51307.1 - 3.3e-06 27.0 0.1 6e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KXL51307.1 - 7.2e-05 23.1 0.0 0.00013 22.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXL51307.1 - 0.0015 18.6 0.1 0.0031 17.6 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KXL51307.1 - 0.0063 16.0 0.3 0.011 15.3 0.3 1.3 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_4 PF13420.7 KXL51307.1 - 0.073 13.2 0.0 0.12 12.5 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1242 PF06842.12 KXL51308.1 - 8.1e-19 67.1 1.4 1.1e-18 66.7 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) JAB PF01398.21 KXL51309.1 - 8.5e-22 77.4 0.0 1.3e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KXL51309.1 - 3e-18 66.3 0.1 5e-18 65.6 0.1 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.13 KXL51309.1 - 8.7e-06 25.9 0.0 1.7e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) TFIID-18kDa PF02269.16 KXL51310.1 - 3.1e-13 49.5 0.0 4.3e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit PROL5-SMR PF15621.6 KXL51310.1 - 0.028 14.9 0.5 0.043 14.3 0.5 1.4 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family UTP25 PF06862.12 KXL51311.1 - 7.8e-133 443.7 0.0 9.6e-133 443.4 0.0 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 baeRF_family11 PF18855.1 KXL51312.1 - 0.042 14.2 0.0 0.054 13.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 11 Aldo_ket_red PF00248.21 KXL51313.1 - 2.3e-70 237.1 0.0 2.8e-70 236.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family TusA PF01206.17 KXL51313.1 - 0.15 11.9 0.0 0.59 10.0 0.0 2.0 2 0 0 2 2 2 0 Sulfurtransferase TusA MFS_1 PF07690.16 KXL51314.1 - 3.7e-14 52.4 35.1 3.7e-14 52.4 35.1 3.3 2 2 1 3 3 3 2 Major Facilitator Superfamily AIF-MLS PF14962.6 KXL51315.1 - 3.1 7.7 7.7 0.13 12.3 0.9 2.0 2 0 0 2 2 2 0 Mitochondria Localisation Sequence MethyltransfD12 PF02086.15 KXL51316.1 - 1.9e-05 24.5 0.0 2.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase HR1 PF02185.16 KXL51317.1 - 0.05 13.7 0.1 0.098 12.8 0.1 1.4 1 0 0 1 1 1 0 Hr1 repeat Meth_synt_2 PF01717.18 KXL51318.1 - 1.3e-151 504.4 0.0 5.2e-147 489.3 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KXL51318.1 - 5.5e-122 407.2 0.1 6.3e-116 387.3 0.0 2.7 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 KXL51318.1 - 7.8e-05 22.0 0.0 0.024 13.8 0.0 2.7 3 0 0 3 3 3 2 Uroporphyrinogen decarboxylase (URO-D) Bac_small_YrzI PF09501.10 KXL51318.1 - 7.2 6.8 7.1 2.4 8.4 2.7 2.5 3 0 0 3 3 3 0 Probable sporulation protein (Bac_small_yrzI) Zn_clus PF00172.18 KXL51319.1 - 0.00069 19.7 1.4 0.00069 19.7 1.4 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXL51319.1 - 0.028 13.2 3.7 0.015 14.1 1.4 1.7 2 0 0 2 2 2 0 Fungal specific transcription factor domain YTH PF04146.15 KXL51320.1 - 6.2e-12 45.8 0.0 5.1e-11 42.8 0.0 2.5 2 1 0 2 2 2 1 YT521-B-like domain HtrL_YibB PF09612.10 KXL51320.1 - 0.22 11.0 0.0 0.84 9.1 0.0 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (HtrL_YibB) HORMA PF02301.18 KXL51321.1 - 1.1e-38 133.0 0.0 5.3e-38 130.7 0.0 2.0 2 0 0 2 2 2 1 HORMA domain PHD PF00628.29 KXL51321.1 - 2.1e-05 24.3 8.6 4.7e-05 23.2 8.6 1.5 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 KXL51321.1 - 0.026 14.5 4.8 0.057 13.3 4.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_2 PF13831.6 KXL51321.1 - 0.29 10.7 3.9 0.72 9.5 3.9 1.7 1 0 0 1 1 1 0 PHD-finger DNA_RNApol_7kD PF03604.13 KXL51321.1 - 0.55 10.0 3.5 0.62 9.8 0.7 2.2 1 1 1 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Stc1 PF12898.7 KXL51321.1 - 1.6 9.3 5.6 5.4 7.6 4.0 2.4 2 0 0 2 2 2 0 Stc1 domain SLAIN PF15301.6 KXL51322.1 - 0.071 12.4 3.6 0.099 11.9 3.6 1.2 1 0 0 1 1 1 0 SLAIN motif-containing family Ras PF00071.22 KXL51323.1 - 3.2e-15 56.1 0.0 7.5e-15 54.9 0.0 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KXL51323.1 - 0.0015 18.7 0.0 0.11 12.7 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Choline_kin_N PF04428.14 KXL51323.1 - 0.023 14.3 0.1 5.5 6.7 0.1 2.5 2 0 0 2 2 2 0 Choline kinase N terminus Arf PF00025.21 KXL51323.1 - 0.13 11.7 0.1 0.84 9.1 0.0 2.1 3 0 0 3 3 3 0 ADP-ribosylation factor family NACHT PF05729.12 KXL51323.1 - 0.13 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 KXL51323.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Pribosyl_synth PF14572.6 KXL51324.1 - 6.1e-36 124.2 0.3 5.8e-32 111.2 0.1 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KXL51324.1 - 3.7e-35 120.4 0.0 7.9e-35 119.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KXL51324.1 - 7.8e-12 45.0 0.1 1.6e-11 44.0 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KXL51324.1 - 0.035 13.5 0.1 0.058 12.8 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase tRNA-synt_1 PF00133.22 KXL51325.1 - 7.2e-199 661.9 0.1 7.3e-198 658.6 0.0 2.3 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KXL51325.1 - 2.1e-23 83.0 0.0 1.2e-22 80.5 0.0 2.1 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KXL51325.1 - 3.9e-15 55.5 0.0 0.00016 20.6 0.0 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KXL51325.1 - 0.0097 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain MFS_1 PF07690.16 KXL51326.1 - 2.8e-37 128.5 25.4 2.8e-37 128.5 25.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.18 KXL51328.1 - 2.7e-25 88.9 0.0 4.3e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL51328.1 - 1.2e-06 28.5 10.7 3.3e-06 27.1 10.7 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 7TM_GPCR_Srsx PF10320.9 KXL51329.1 - 0.029 13.8 0.1 0.052 12.9 0.1 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx MerR PF00376.23 KXL51330.1 - 0.11 12.3 0.1 0.45 10.3 0.0 2.1 2 0 0 2 2 2 0 MerR family regulatory protein KinB_sensor PF16767.5 KXL51330.1 - 0.45 11.0 8.6 0.092 13.2 1.7 2.6 2 1 1 3 3 3 0 Sensor domain of alginate biosynthesis sensor protein KinB Na_Ca_ex PF01699.24 KXL51331.1 - 4.2e-47 159.9 38.2 5.9e-24 84.7 17.9 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein RraA-like PF03737.15 KXL51332.1 - 4.1e-21 75.7 0.0 6.2e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Aldolase/RraA CutC PF03932.14 KXL51333.1 - 9.2e-59 198.3 0.0 1.1e-58 198.1 0.0 1.0 1 0 0 1 1 1 1 CutC family Thiolase_N PF00108.23 KXL51334.1 - 2.3e-73 246.8 1.5 2.3e-73 246.8 1.5 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXL51334.1 - 4.6e-44 149.0 0.1 1.2e-43 147.6 0.1 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 KXL51334.1 - 0.014 15.5 0.0 0.042 14.0 0.0 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.26 KXL51334.1 - 0.065 12.8 2.9 0.36 10.4 0.8 3.0 2 1 2 4 4 4 0 Beta-ketoacyl synthase, N-terminal domain SOG2 PF10428.9 KXL51335.1 - 0.0081 15.4 1.1 0.0092 15.2 1.1 1.2 1 0 0 1 1 1 1 RAM signalling pathway protein Acyltransferase PF01553.21 KXL51337.1 - 3.7e-10 39.5 0.0 1e-05 25.2 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase DUF3390 PF11870.8 KXL51338.1 - 0.0036 17.6 0.5 0.0094 16.3 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3390) SET PF00856.28 KXL51338.1 - 0.094 13.1 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 SET domain Glyco_hydro_3_C PF01915.22 KXL51340.1 - 5.4e-62 209.4 0.0 1.3e-61 208.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXL51340.1 - 4.3e-45 154.5 0.0 7.2e-45 153.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXL51340.1 - 1.7e-18 66.5 0.1 3.9e-18 65.3 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KXL51340.1 - 3.3e-15 56.2 0.1 6.2e-15 55.3 0.1 1.4 1 0 0 1 1 1 1 PA14 domain GLEYA PF10528.9 KXL51340.1 - 0.015 15.7 0.2 0.038 14.4 0.2 1.7 1 0 0 1 1 1 0 GLEYA domain Lipase_GDSL_2 PF13472.6 KXL51340.1 - 0.024 15.0 0.1 0.052 13.9 0.1 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family TPT PF03151.16 KXL51341.1 - 4.6e-32 111.5 26.1 5.6e-32 111.3 26.1 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KXL51341.1 - 2.7e-11 43.2 23.8 2.3e-10 40.2 23.8 1.9 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KXL51341.1 - 0.11 12.6 38.4 0.024 14.8 16.6 2.2 2 0 0 2 2 2 0 EamA-like transporter family CorC_HlyC PF03471.17 KXL51341.1 - 0.18 11.8 0.0 0.47 10.5 0.0 1.6 1 0 0 1 1 1 0 Transporter associated domain DEAD PF00270.29 KXL51342.1 - 1.1e-34 119.7 0.0 1.1e-33 116.5 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXL51342.1 - 3e-21 75.8 0.0 1.1e-20 74.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KXL51342.1 - 5.8e-16 58.5 0.0 1.2e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KXL51342.1 - 3.1e-09 37.1 0.0 6.6e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 KXL51342.1 - 0.15 12.1 0.0 0.63 10.0 0.0 2.0 2 0 0 2 2 2 0 Flavivirus DEAD domain INCENP_ARK-bind PF03941.15 KXL51343.1 - 1.7e-15 56.7 3.9 2.5e-15 56.1 0.2 2.8 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region GRASP55_65 PF04495.14 KXL51344.1 - 4.5e-47 159.8 0.0 4.6e-45 153.3 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 KXL51344.1 - 0.00021 21.1 0.0 0.18 11.7 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 KXL51344.1 - 0.043 14.2 0.0 3 8.2 0.0 2.4 2 0 0 2 2 2 0 PDZ domain dsrm PF00035.26 KXL51346.1 - 0.00071 20.2 0.0 0.0022 18.7 0.0 1.8 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KXL51346.1 - 0.049 13.9 0.3 0.11 12.7 0.3 1.6 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Glyco_hydro_3_C PF01915.22 KXL51347.1 - 2.3e-46 158.3 0.0 3.6e-46 157.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXL51347.1 - 2.9e-38 132.0 0.0 5.8e-38 131.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXL51347.1 - 3.8e-17 62.2 0.0 6.9e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain NTP_transferase PF00483.23 KXL51348.1 - 1.2e-53 182.2 0.0 2.2e-53 181.4 0.0 1.4 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 KXL51348.1 - 1.6e-18 65.7 11.4 4.1e-11 42.1 1.3 4.0 2 2 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KXL51348.1 - 2.7e-10 40.8 0.0 3.7e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KXL51348.1 - 4.9e-06 26.2 5.0 7.9e-06 25.5 0.7 3.1 2 1 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KXL51348.1 - 0.00012 20.4 0.1 0.00032 19.0 0.0 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4954) IspD PF01128.19 KXL51348.1 - 0.058 13.1 0.0 0.093 12.5 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Methyltransf_23 PF13489.6 KXL51349.1 - 2.6e-17 63.1 0.0 1e-16 61.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXL51349.1 - 3.1e-10 40.6 0.0 7.6e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXL51349.1 - 3.7e-07 30.7 0.0 9.5e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXL51349.1 - 3.9e-07 30.0 0.1 6.6e-06 26.0 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXL51349.1 - 0.00074 19.0 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.12 KXL51349.1 - 0.001 19.7 0.0 0.0037 18.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KXL51349.1 - 0.006 16.7 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KXL51349.1 - 0.052 12.8 0.0 0.082 12.2 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain p450 PF00067.22 KXL51350.1 - 1.8e-44 152.3 0.0 2.4e-44 151.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S10 PF00450.22 KXL51351.1 - 4.1e-75 253.8 0.9 8e-75 252.8 0.9 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase ATP13 PF12921.7 KXL51353.1 - 0.068 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ATPase expression Suc_Fer-like PF06999.12 KXL51354.1 - 1.8e-70 236.8 0.0 2.2e-70 236.5 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like zf-RING_2 PF13639.6 KXL51356.1 - 9.7e-08 32.2 6.5 2.6e-07 30.9 6.5 1.8 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 KXL51356.1 - 1.6e-05 24.9 3.8 4.2e-05 23.6 3.8 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KXL51356.1 - 0.0001 22.3 0.6 0.00024 21.1 0.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KXL51356.1 - 0.00011 22.4 4.7 0.00032 20.9 4.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 KXL51356.1 - 0.0044 16.6 3.8 0.01 15.4 3.8 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type C1_1 PF00130.22 KXL51356.1 - 0.0048 16.8 1.0 0.0048 16.8 1.0 1.8 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RINGv PF12906.7 KXL51356.1 - 0.029 14.5 5.4 0.054 13.6 4.7 2.0 1 1 1 2 2 2 0 RING-variant domain zf-C3HC4_3 PF13920.6 KXL51356.1 - 0.071 13.0 4.0 0.16 11.9 4.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXL51356.1 - 0.099 12.5 6.6 0.2 11.6 6.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXL51356.1 - 0.12 12.2 5.8 0.34 10.8 5.8 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_9 PF13901.6 KXL51356.1 - 0.3 11.1 5.6 0.26 11.2 3.6 1.9 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon zf-RING-like PF08746.11 KXL51356.1 - 2.1 8.7 7.9 0.92 9.9 5.2 1.9 2 0 0 2 2 1 0 RING-like domain zf-RING_4 PF14570.6 KXL51356.1 - 4 7.3 5.0 1.1e+02 2.7 5.0 2.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DEAD_2 PF06733.15 KXL51357.1 - 1.7e-56 190.6 0.2 1.2e-55 187.9 0.0 2.2 2 0 0 2 2 2 1 DEAD_2 HBB PF06777.11 KXL51357.1 - 2.8e-50 170.6 1.9 1.3e-45 155.5 0.6 2.6 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 KXL51357.1 - 1.2e-43 149.2 0.1 3.8e-43 147.6 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.15 KXL51357.1 - 4.4e-05 23.5 0.0 0.0018 18.3 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KXL51357.1 - 0.00094 19.0 0.0 0.072 12.8 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.23 KXL51357.1 - 0.075 11.7 0.0 1.4 7.6 0.0 2.1 1 1 0 1 1 1 0 SNF2 family N-terminal domain PhoH PF02562.16 KXL51357.1 - 0.099 12.1 0.1 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein GH131_N PF18271.1 KXL51358.1 - 2.8e-63 214.0 0.0 2.8e-63 214.0 0.0 1.4 2 0 0 2 2 2 1 Glycoside hydrolase 131 catalytic N-terminal domain TPT PF03151.16 KXL51359.1 - 2.4e-20 73.1 11.6 4.4e-20 72.2 11.6 1.3 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KXL51359.1 - 1.8e-05 24.9 30.7 0.014 15.6 6.3 2.8 2 1 0 2 2 2 2 EamA-like transporter family DUF4695 PF15766.5 KXL51359.1 - 0.1 12.9 0.7 0.18 12.1 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4695) Nop14 PF04147.12 KXL51359.1 - 3 5.9 4.3 3.9 5.6 4.3 1.0 1 0 0 1 1 1 0 Nop14-like family Rhodanese PF00581.20 KXL51360.1 - 3.8e-13 49.9 0.1 7.3e-13 49.0 0.1 1.4 1 0 0 1 1 1 1 Rhodanese-like domain cwf21 PF08312.12 KXL51362.1 - 1.4e-17 63.6 12.3 1.4e-17 63.6 12.3 2.0 3 0 0 3 3 3 1 cwf21 domain GvpG PF05120.12 KXL51362.1 - 5.5 7.1 12.0 1 9.4 1.8 2.4 2 1 0 2 2 2 0 Gas vesicle protein G D123 PF07065.14 KXL51363.1 - 6.5e-110 367.1 0.9 8.6e-110 366.7 0.9 1.2 1 0 0 1 1 1 1 D123 HSP70 PF00012.20 KXL51364.1 - 1.8e-262 871.9 8.6 2e-262 871.7 8.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXL51364.1 - 1.2e-17 63.7 0.1 2.1e-16 59.7 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KXL51364.1 - 0.0026 17.5 0.0 0.0087 15.8 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 KXL51364.1 - 0.004 17.5 2.3 6.8 7.2 0.0 3.4 3 1 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 KXL51364.1 - 0.024 13.9 0.1 0.053 12.8 0.1 1.6 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase StbA PF06406.11 KXL51364.1 - 0.036 13.3 0.0 0.076 12.2 0.0 1.5 1 0 0 1 1 1 0 StbA protein DUF2062 PF09835.9 KXL51366.1 - 0.035 14.0 0.1 0.039 13.8 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Molybdopterin PF00384.22 KXL51367.1 - 9.8e-67 225.8 0.0 1.3e-64 218.8 0.0 2.2 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 KXL51367.1 - 2e-21 75.8 0.3 7.6e-21 74.0 0.3 2.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 KXL51367.1 - 2.8e-17 62.0 0.2 2.8e-17 62.0 0.2 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 KXL51367.1 - 2.9e-12 47.1 0.0 6.3e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 KXL51367.1 - 4.5e-08 32.9 0.6 4.5e-08 32.9 0.6 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Lyx_isomer PF07385.12 KXL51367.1 - 0.053 12.8 0.0 0.09 12.0 0.0 1.2 1 0 0 1 1 1 0 D-lyxose isomerase Fer4 PF00037.27 KXL51367.1 - 0.12 12.3 1.1 3.5 7.6 0.3 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_19 PF06902.11 KXL51367.1 - 0.15 12.2 0.2 33 4.7 0.1 2.6 2 0 0 2 2 2 0 Divergent 4Fe-4S mono-cluster SUI1 PF01253.22 KXL51368.1 - 3.4e-14 53.1 0.0 8.4e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 KXL51368.1 - 9.2e-08 32.7 0.9 0.026 15.2 0.0 2.8 3 0 0 3 3 3 2 Pre-PUA-like domain Kin17_mid PF10357.9 KXL51368.1 - 0.0019 18.1 0.0 0.0035 17.3 0.0 1.3 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein SWIB PF02201.18 KXL51368.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 SWIB/MDM2 domain GntR PF00392.21 KXL51368.1 - 0.36 10.5 1.9 5.4 6.7 0.0 2.8 3 0 0 3 3 3 0 Bacterial regulatory proteins, gntR family Mak10 PF04112.13 KXL51369.1 - 1.9e-57 193.5 0.0 3.5e-57 192.6 0.0 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Prefoldin_2 PF01920.20 KXL51369.1 - 0.0066 16.4 0.8 0.014 15.3 0.2 1.9 1 1 0 1 1 1 1 Prefoldin subunit ATP-synt_Eps PF04627.13 KXL51370.1 - 6.3e-25 86.9 1.6 1e-24 86.2 1.6 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Peptidase_M16 PF00675.20 KXL51371.1 - 5.9e-12 45.8 0.0 1.3e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KXL51371.1 - 8.2e-11 42.3 0.0 1.4e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain RNA_pol_Rpc82 PF05645.13 KXL51372.1 - 2.6e-27 96.2 0.0 1.5e-25 90.5 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 KXL51372.1 - 4.5e-13 49.1 1.0 2.9e-05 24.1 0.2 4.2 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 KXL51372.1 - 1.3e-07 31.4 0.3 0.00022 21.0 0.6 2.8 3 0 0 3 3 3 2 TFIIE alpha subunit TrmB PF01978.19 KXL51372.1 - 0.001 18.9 0.1 0.025 14.5 0.0 3.3 4 0 0 4 4 4 1 Sugar-specific transcriptional regulator TrmB HTH_DeoR PF08220.12 KXL51372.1 - 0.0018 18.0 0.0 1.6 8.5 0.0 3.3 3 0 0 3 3 3 2 DeoR-like helix-turn-helix domain MarR PF01047.22 KXL51372.1 - 0.039 13.9 1.9 20 5.2 0.0 4.4 5 0 0 5 5 5 0 MarR family UPF0061 PF02696.14 KXL51374.1 - 3.5e-127 425.0 0.0 4.4e-127 424.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family DUF4391 PF14335.6 KXL51374.1 - 0.0057 16.4 0.2 0.0099 15.6 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4391) HEPN_DZIP3 PF18738.1 KXL51374.1 - 0.046 13.5 0.1 0.73 9.6 0.1 2.2 2 0 0 2 2 2 0 DZIP3/ hRUL138-like HEPN AMP-binding PF00501.28 KXL51375.1 - 8e-27 93.9 0.0 9.7e-27 93.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme ATP11 PF06644.11 KXL51376.1 - 3.8e-95 318.8 0.0 4.5e-95 318.5 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Peptidase_M19 PF01244.21 KXL51377.1 - 3.8e-97 325.3 0.0 4.4e-97 325.1 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Ilm1 PF10311.9 KXL51378.1 - 1.9e-55 187.0 3.8 2.2e-55 186.8 3.8 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Ribosomal_L36e PF01158.18 KXL51381.1 - 2.2e-42 143.2 5.0 2.5e-42 143.1 5.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e PBS_linker_poly PF00427.21 KXL51381.1 - 0.019 15.0 0.1 0.022 14.8 0.1 1.1 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide LemA PF04011.12 KXL51381.1 - 0.13 12.1 0.2 0.16 11.8 0.2 1.1 1 0 0 1 1 1 0 LemA family Acetyltransf_7 PF13508.7 KXL51382.1 - 2.6e-07 31.0 0.1 4e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXL51382.1 - 4.1e-07 30.2 0.0 6.4e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXL51382.1 - 2.4e-06 27.5 0.0 3.7e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXL51382.1 - 5.2e-06 26.6 0.3 1.5e-05 25.0 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXL51382.1 - 0.00034 20.5 0.0 0.00069 19.5 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein GNAT_acetyltran PF12746.7 KXL51382.1 - 0.00051 19.7 0.0 0.00073 19.2 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase TUG-UBL1 PF11470.8 KXL51383.1 - 1.8e-22 79.3 0.1 4.2e-22 78.2 0.1 1.7 1 0 0 1 1 1 1 TUG ubiquitin-like domain UBX PF00789.20 KXL51383.1 - 0.00014 22.0 0.0 0.00066 19.8 0.0 2.2 2 0 0 2 2 2 1 UBX domain RBD PF02196.15 KXL51383.1 - 0.0015 18.6 0.0 0.0042 17.1 0.0 1.7 1 0 0 1 1 1 1 Raf-like Ras-binding domain YukD PF08817.10 KXL51383.1 - 0.0099 16.6 0.4 31 5.4 0.2 3.5 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein YukD Med3 PF11593.8 KXL51383.1 - 0.018 14.3 2.1 0.027 13.7 2.1 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal AAA_22 PF13401.6 KXL51383.1 - 0.057 13.7 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain UN_NPL4 PF11543.8 KXL51383.1 - 0.067 13.7 0.0 0.77 10.3 0.0 2.3 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 PB1 PF00564.24 KXL51383.1 - 0.1 12.6 0.0 0.35 10.8 0.0 2.0 1 0 0 1 1 1 0 PB1 domain PBP_N PF17093.5 KXL51383.1 - 0.25 11.6 4.7 0.1 12.8 1.6 1.9 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus PITH PF06201.13 KXL51384.1 - 1.5e-37 129.1 0.0 2.2e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 KXL51384.1 - 2.3e-27 95.0 0.0 4.6e-27 94.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KXL51384.1 - 6.6e-05 23.3 0.2 0.00032 21.1 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KXL51384.1 - 8.5e-05 22.8 0.0 0.085 13.2 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 KXL51384.1 - 0.00019 20.9 0.0 0.00054 19.4 0.0 1.6 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 KXL51384.1 - 0.04 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Redoxin PF08534.10 KXL51384.1 - 0.11 12.2 0.2 6.6 6.4 0.1 2.3 1 1 1 2 2 2 0 Redoxin zf-C2H2 PF00096.26 KXL51385.1 - 5.4e-12 45.5 14.2 6.8e-07 29.4 1.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXL51385.1 - 1.5e-08 34.8 11.8 0.00042 20.9 0.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXL51385.1 - 3.9e-06 27.0 13.7 3.3e-05 24.1 6.0 3.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KXL51385.1 - 5.5e-06 26.5 5.1 0.013 15.7 1.0 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXL51385.1 - 0.00013 22.2 4.8 0.028 14.8 0.3 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KXL51385.1 - 0.0022 18.0 8.8 0.082 12.9 0.9 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-LYAR PF08790.11 KXL51385.1 - 0.0055 16.6 4.8 0.11 12.4 0.7 2.6 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf_C2H2_ZHX PF18387.1 KXL51385.1 - 0.011 15.3 3.8 1.9 8.2 0.2 2.4 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_11 PF16622.5 KXL51385.1 - 0.3 10.9 9.6 1.5 8.7 0.1 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-UBR PF02207.20 KXL51385.1 - 0.32 11.2 1.8 0.6 10.3 1.8 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) DUF629 PF04780.12 KXL51385.1 - 0.43 9.1 2.5 10 4.5 1.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF629) LIM PF00412.22 KXL51385.1 - 0.45 10.8 3.9 0.94 9.7 3.9 1.5 1 0 0 1 1 1 0 LIM domain zf-C2HE PF16278.5 KXL51385.1 - 0.74 10.3 6.7 9.3 6.8 0.7 2.4 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Zn-ribbon_8 PF09723.10 KXL51385.1 - 0.83 9.8 3.2 5.5 7.2 0.4 2.4 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 KXL51385.1 - 1.2 9.5 5.0 4.1 7.8 0.6 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-trcl PF13451.6 KXL51385.1 - 1.4 8.8 4.2 1.6 8.7 0.6 2.3 2 0 0 2 2 2 0 Probable zinc-ribbon domain zf-BED PF02892.15 KXL51385.1 - 1.9 8.6 7.0 1 9.4 2.8 2.3 1 1 1 2 2 2 0 BED zinc finger NAD_binding_4 PF07993.12 KXL51387.1 - 9.3e-37 126.6 0.0 1.5e-36 125.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KXL51387.1 - 4.5e-23 81.5 0.0 7.3e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KXL51387.1 - 3.9e-08 33.1 0.1 1.3e-07 31.4 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KXL51387.1 - 1e-05 25.8 0.0 2.2e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site G-patch_2 PF12656.7 KXL51388.1 - 2.6e-24 85.1 0.3 1.3e-23 82.8 0.3 2.3 1 0 0 1 1 1 1 G-patch domain G-patch PF01585.23 KXL51388.1 - 0.00053 19.8 0.7 0.0012 18.7 0.7 1.7 1 0 0 1 1 1 1 G-patch domain DUF4589 PF15252.6 KXL51389.1 - 1.1 9.2 6.8 2.9 7.8 4.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4589) HTH_Tnp_Tc5 PF03221.16 KXL51390.1 - 0.00019 21.4 0.2 0.0005 20.1 0.1 1.7 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 KXL51390.1 - 0.17 11.6 0.1 0.27 11.0 0.1 1.2 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Ferritin_2 PF13668.6 KXL51392.1 - 0.00042 20.5 0.0 0.00079 19.6 0.0 1.4 1 0 0 1 1 1 1 Ferritin-like domain Proteasome PF00227.26 KXL51394.1 - 1.5e-29 102.9 0.2 6.6e-28 97.5 0.2 2.2 1 1 0 1 1 1 1 Proteasome subunit MDM31_MDM32 PF08118.11 KXL51396.1 - 3.2e-227 755.4 0.0 6.3e-227 754.4 0.0 1.4 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins eIF3m_C_helix PF18005.1 KXL51397.1 - 3.4e-09 36.3 2.4 7.4e-09 35.1 2.4 1.6 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix PCI PF01399.27 KXL51397.1 - 2e-08 34.7 0.0 3.3e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 PCI domain Dsl1_C PF11989.8 KXL51398.1 - 1.9e-05 24.5 0.0 3.7e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal DNA_pol_E_B PF04042.16 KXL51399.1 - 7.9e-41 139.7 0.0 1.7e-40 138.6 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 KXL51399.1 - 5.4e-37 126.8 0.0 8.8e-37 126.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain G-patch PF01585.23 KXL51401.1 - 0.013 15.4 0.0 0.05 13.5 0.0 2.1 1 1 0 1 1 1 0 G-patch domain DDRGK PF09756.9 KXL51401.1 - 0.15 11.7 13.9 0.27 10.8 13.9 1.4 1 0 0 1 1 1 0 DDRGK domain G-patch_2 PF12656.7 KXL51401.1 - 0.15 12.2 0.0 0.15 12.2 0.0 2.3 2 0 0 2 2 2 0 G-patch domain SAPS PF04499.15 KXL51401.1 - 1.1 8.0 8.7 1.4 7.6 8.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CAF-1_p150 PF11600.8 KXL51401.1 - 2.1 8.0 22.3 3.6 7.3 22.3 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RR_TM4-6 PF06459.12 KXL51401.1 - 2.1 8.1 12.1 3.1 7.6 12.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ATP-synt_S1 PF05827.12 KXL51402.1 - 1.1e-06 28.5 0.0 1.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) MalM PF07148.12 KXL51402.1 - 0.047 13.5 0.1 0.094 12.5 0.1 1.5 1 0 0 1 1 1 0 Maltose operon periplasmic protein precursor (MalM) Glyco_hydro_3_C PF01915.22 KXL51404.1 - 3.3e-42 144.8 0.0 5.9e-42 143.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXL51404.1 - 6.3e-37 127.6 0.0 1.1e-36 126.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXL51404.1 - 2.6e-20 72.3 0.3 4.3e-20 71.6 0.3 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain FAD_binding_2 PF00890.24 KXL51405.1 - 1.3e-40 139.8 0.6 8.8e-40 137.0 0.6 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXL51405.1 - 1e-08 35.1 2.3 1e-08 35.1 2.3 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KXL51405.1 - 1.2e-08 34.8 0.3 3e-07 30.1 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXL51405.1 - 2.1e-06 26.7 1.4 0.0043 15.8 0.9 3.2 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_2 PF07992.14 KXL51405.1 - 6.7e-06 25.5 0.2 0.0099 15.1 0.2 2.8 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXL51405.1 - 2.6e-05 23.7 0.4 0.00075 18.8 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 KXL51405.1 - 0.00033 20.0 0.5 0.01 15.1 0.4 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXL51405.1 - 0.00078 18.6 1.1 0.00078 18.6 1.1 2.3 3 0 0 3 3 3 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KXL51405.1 - 0.0017 17.7 0.3 0.0033 16.8 0.3 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 KXL51405.1 - 0.0067 16.6 0.9 0.022 15.0 0.9 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXL51405.1 - 0.037 14.6 1.1 2.1 9.0 0.5 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KXL51405.1 - 0.046 14.2 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding GST_N_3 PF13417.6 KXL51406.1 - 3.9e-12 46.4 0.0 8.7e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXL51406.1 - 8.5e-09 35.6 0.0 2.1e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXL51406.1 - 8e-05 22.8 0.0 0.00017 21.8 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXL51406.1 - 0.0029 17.6 0.0 0.0049 16.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXL51406.1 - 0.13 12.5 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GCD14 PF08704.10 KXL51407.1 - 1.7e-66 224.5 1.8 5.6e-65 219.5 1.8 2.2 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit CMAS PF02353.20 KXL51407.1 - 0.005 16.2 0.0 0.0092 15.3 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DHR10 PF18595.1 KXL51407.1 - 0.012 15.6 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Trimer_CC PF08954.11 KXL51407.1 - 0.054 13.1 0.4 0.16 11.6 0.4 1.8 1 0 0 1 1 1 0 Trimerisation motif M16C_assoc PF08367.11 KXL51408.1 - 2.4e-74 249.6 0.0 3.5e-74 249.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 KXL51408.1 - 5.4e-29 101.5 0.0 4.1e-20 72.6 0.0 2.9 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KXL51408.1 - 1.2e-08 35.1 0.0 4.8e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) GST_N_3 PF13417.6 KXL51409.1 - 3.6e-05 24.1 0.0 7.6e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXL51409.1 - 0.0012 19.1 0.0 0.0024 18.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Taxilin PF09728.9 KXL51410.1 - 2e-76 257.1 59.6 2.9e-53 181.1 33.7 2.3 2 0 0 2 2 2 2 Myosin-like coiled-coil protein ATG16 PF08614.11 KXL51410.1 - 0.0025 18.1 8.6 0.0025 18.1 8.6 3.6 2 2 1 3 3 3 1 Autophagy protein 16 (ATG16) GD_AH_C PF04295.13 KXL51410.1 - 0.0038 16.1 0.5 0.0083 15.0 0.5 1.6 1 0 0 1 1 1 1 D-galactarate dehydratase / Altronate hydrolase, C terminus Speriolin_N PF15058.6 KXL51410.1 - 0.016 15.3 5.1 1.9 8.5 0.2 3.6 2 1 1 3 3 3 0 Speriolin N terminus DUF16 PF01519.16 KXL51410.1 - 0.26 11.8 0.0 0.26 11.8 0.0 4.3 3 1 0 3 3 3 0 Protein of unknown function DUF16 FUSC PF04632.12 KXL51410.1 - 0.78 8.2 19.5 0.013 14.1 6.8 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF812 PF05667.11 KXL51410.1 - 2 7.2 47.4 0.88 8.4 18.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Exonuc_VII_L PF02601.15 KXL51410.1 - 3.5 7.1 35.5 2.1 7.8 13.1 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit ApbA PF02558.16 KXL51411.1 - 4.3e-27 94.6 0.0 5.5e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA CorA PF01544.18 KXL51413.1 - 0.011 15.1 0.2 0.017 14.4 0.2 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein HMMR_N PF15905.5 KXL51415.1 - 6.6e-05 22.5 19.0 6.6e-05 22.5 19.0 2.0 1 1 1 2 2 2 1 Hyaluronan mediated motility receptor N-terminal Csm1_N PF18504.1 KXL51415.1 - 0.014 15.7 0.5 0.014 15.7 0.5 4.4 2 2 2 4 4 4 0 Csm1 N-terminal domain YjbH PF06082.11 KXL51415.1 - 0.022 13.6 13.4 0.027 13.3 13.4 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH SHE3 PF17078.5 KXL51415.1 - 0.049 13.3 25.5 0.22 11.2 25.2 2.1 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 DASH_Dam1 PF08653.10 KXL51415.1 - 0.18 11.6 3.4 1.2 9.0 0.1 3.2 2 1 1 3 3 3 0 DASH complex subunit Dam1 ZapB PF06005.12 KXL51415.1 - 0.58 10.6 0.1 0.58 10.6 0.1 4.7 2 1 1 3 3 3 0 Cell division protein ZapB TMPIT PF07851.13 KXL51415.1 - 1.6 7.9 19.4 1.5 8.0 3.0 2.1 2 0 0 2 2 2 0 TMPIT-like protein DUF3584 PF12128.8 KXL51415.1 - 3 5.2 33.6 4.7 4.6 33.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4407 PF14362.6 KXL51415.1 - 6.7 6.0 25.2 45 3.2 24.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 KXL51415.1 - 6.8 5.7 32.4 0.94 8.5 19.4 2.4 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ribosomal_S30 PF04758.14 KXL51417.1 - 6.5e-30 103.1 8.1 7.1e-30 103.0 8.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Pyrid_oxidase_2 PF13883.6 KXL51418.1 - 4.7e-37 127.6 0.0 6.9e-36 123.8 0.0 2.1 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF4380 PF14315.6 KXL51418.1 - 0.091 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4380) SET PF00856.28 KXL51419.1 - 2.1e-13 51.0 0.0 5.1e-13 49.8 0.0 1.7 1 1 0 1 1 1 1 SET domain OPT PF03169.15 KXL51420.1 - 3.5e-145 485.1 48.9 4.2e-145 484.8 48.9 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Glyco_hydro_88 PF07470.13 KXL51421.1 - 3.3e-94 315.8 4.1 3.8e-94 315.6 4.1 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 KXL51421.1 - 0.0018 16.9 0.2 0.0029 16.2 0.0 1.4 2 0 0 2 2 2 1 Beta-L-arabinofuranosidase, GH127 p450 PF00067.22 KXL51422.1 - 2e-46 158.7 0.0 3e-46 158.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Med12-LCEWAV PF12145.8 KXL51423.1 - 0.076 11.9 0.1 0.089 11.6 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain AC_N PF16214.5 KXL51423.1 - 8.7 5.3 8.7 12 4.9 8.7 1.4 1 1 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Sugar_tr PF00083.24 KXL51424.1 - 2.5e-78 264.0 19.7 3e-78 263.7 19.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL51424.1 - 4.6e-24 85.0 25.4 2.6e-17 62.8 3.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF1687 PF07955.11 KXL51425.1 - 5.2e-32 111.0 0.1 6.7e-32 110.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) Mif2_N PF15624.6 KXL51425.1 - 0.043 14.5 0.1 0.055 14.2 0.1 1.2 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal SPT6_acidic PF14632.6 KXL51427.1 - 0.0095 16.5 0.7 0.0095 16.5 0.7 3.6 3 0 0 3 3 3 1 Acidic N-terminal SPT6 RNase_PH PF01138.21 KXL51428.1 - 2.3e-19 70.2 0.0 3.6e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KXL51428.1 - 0.13 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Neuroparsin PF07327.11 KXL51429.1 - 0.0061 17.0 0.2 0.012 16.0 0.2 1.4 1 0 0 1 1 1 1 Neuroparsin SnoaL PF07366.12 KXL51430.1 - 0.013 15.3 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase Cyclin PF08613.11 KXL51431.1 - 0.00016 22.0 0.1 0.00047 20.5 0.1 2.0 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KXL51431.1 - 0.031 14.0 0.0 0.068 12.9 0.0 1.6 1 0 0 1 1 1 0 Cyclin, N-terminal domain Pro_isomerase PF00160.21 KXL51432.1 - 3.7e-56 189.8 0.0 4.1e-56 189.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ADH_N PF08240.12 KXL51433.1 - 7.7e-27 93.3 0.5 1.3e-26 92.6 0.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXL51433.1 - 4.5e-07 29.9 0.1 8.9e-07 28.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KXL51433.1 - 3.6e-05 23.6 0.0 3.6e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated HI0933_like PF03486.14 KXL51433.1 - 0.005 15.6 0.2 0.021 13.5 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein Glu_dehyd_C PF16912.5 KXL51433.1 - 0.015 14.8 0.0 0.14 11.6 0.0 2.0 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus FAD_binding_2 PF00890.24 KXL51433.1 - 0.065 12.3 0.1 0.097 11.7 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 KXL51433.1 - 0.071 12.4 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KXL51433.1 - 0.19 10.9 0.1 0.28 10.4 0.1 1.1 1 0 0 1 1 1 0 FAD binding domain Pkinase PF00069.25 KXL51434.1 - 1.1e-59 202.0 0.0 2e-39 135.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXL51434.1 - 2.8e-27 95.6 0.1 1e-18 67.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KXL51434.1 - 0.012 14.9 0.1 0.05 12.9 0.0 1.9 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 KXL51434.1 - 0.018 14.9 2.1 0.21 11.5 0.1 3.2 3 2 1 4 4 4 0 Phosphotransferase enzyme family Pkinase_C PF00433.24 KXL51434.1 - 0.1 13.3 0.8 0.28 11.9 0.1 2.2 2 0 0 2 2 2 0 Protein kinase C terminal domain Haspin_kinase PF12330.8 KXL51434.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain His_Phos_2 PF00328.22 KXL51435.1 - 1e-42 146.9 0.0 1.1e-42 146.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) GATA PF00320.27 KXL51436.1 - 4.9e-18 64.4 2.5 6e-18 64.2 2.5 1.1 1 0 0 1 1 1 1 GATA zinc finger SR-25 PF10500.9 KXL51439.1 - 0.0093 15.6 4.9 0.0093 15.6 4.9 3.4 2 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein Ank_2 PF12796.7 KXL51440.1 - 1e-14 54.9 0.0 2.7e-06 27.9 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXL51440.1 - 8e-11 41.9 0.0 7.9e-05 22.9 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KXL51440.1 - 1.4e-10 40.4 0.0 0.0006 20.1 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KXL51440.1 - 2.7e-10 40.3 0.1 0.00015 21.9 0.0 2.9 2 2 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXL51440.1 - 1e-08 35.6 0.0 0.015 15.9 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXL51441.1 - 3.4e-06 27.0 0.0 0.087 13.4 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KXL51441.1 - 3.6e-06 27.5 0.0 8.2e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXL51441.1 - 7.4e-05 23.0 1.4 0.027 14.9 0.0 2.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KXL51441.1 - 9.5e-05 22.9 0.0 0.00029 21.3 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Sugar_tr PF00083.24 KXL51443.1 - 3.1e-82 276.8 29.2 3.6e-82 276.6 29.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL51443.1 - 4.7e-14 52.1 49.1 3.7e-10 39.3 43.6 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXL51443.1 - 0.11 11.3 23.8 0.12 11.2 9.4 2.3 2 0 0 2 2 2 0 MFS_1 like family DUF2715 PF10895.8 KXL51443.1 - 0.18 11.5 2.3 0.36 10.4 2.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2715) Sugar_tr PF00083.24 KXL51444.1 - 5.7e-78 262.8 26.6 7.6e-78 262.4 26.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL51444.1 - 1.6e-22 79.9 35.1 9e-22 77.5 35.1 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXL51444.1 - 1.6e-05 23.5 3.0 3.1e-05 22.6 3.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) His_Phos_1 PF00300.22 KXL51445.1 - 1.1e-34 119.8 0.8 3.3e-17 62.8 0.1 2.4 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) ApbA_C PF08546.11 KXL51446.1 - 6.1e-20 71.7 0.0 9.4e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal PDCD7 PF16021.5 KXL51447.1 - 0.15 11.1 0.0 0.15 11.1 0.0 1.0 1 0 0 1 1 1 0 Programmed cell death protein 7 DUF499 PF04465.12 KXL51448.1 - 2.7e-07 28.8 0.0 4.2e-07 28.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF499) AAA_16 PF13191.6 KXL51448.1 - 0.00044 20.7 0.1 0.0062 16.9 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXL51448.1 - 0.056 13.7 0.0 0.47 10.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KXL51448.1 - 0.18 11.9 0.0 9.3 6.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain PPV_E1_C PF00519.17 KXL51450.1 - 0.068 12.0 0.1 0.078 11.8 0.1 1.0 1 0 0 1 1 1 0 Papillomavirus helicase OAR PF03826.17 KXL51450.1 - 0.21 11.4 1.2 0.36 10.7 0.2 1.9 2 0 0 2 2 2 0 OAR domain Gpr1_Fun34_YaaH PF01184.19 KXL51452.1 - 3.9e-30 105.0 20.5 4.7e-30 104.8 20.5 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Zn_clus PF00172.18 KXL51453.1 - 3.9e-08 33.3 8.9 3.9e-08 33.3 8.9 1.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 KXL51453.1 - 3.5 8.2 12.9 10 6.7 7.1 2.2 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Fungal_trans PF04082.18 KXL51454.1 - 5.9e-20 71.4 0.3 1.2e-19 70.4 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyoxalase PF00903.25 KXL51455.1 - 5.4e-06 26.6 8.6 9.5e-06 25.8 3.5 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KXL51455.1 - 0.014 15.7 0.4 0.19 12.0 0.1 2.6 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FAD_binding_3 PF01494.19 KXL51457.1 - 8.1e-70 235.8 0.0 2.1e-69 234.4 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXL51457.1 - 0.01 15.1 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXL51457.1 - 0.033 14.4 0.9 0.099 12.9 0.9 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXL51457.1 - 0.053 12.6 0.0 0.085 11.9 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 KXL51457.1 - 0.097 11.7 0.2 0.15 11.2 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A p450 PF00067.22 KXL51458.1 - 1.5e-76 258.0 0.0 1.9e-76 257.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1726 PF08351.11 KXL51458.1 - 0.057 13.3 0.1 3 7.8 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1726) Mem_trans PF03547.18 KXL51460.1 - 9.7e-23 80.2 3.3 5.3e-22 77.7 3.3 1.8 1 1 0 1 1 1 1 Membrane transport protein Integrase_H2C2 PF17921.1 KXL51465.1 - 7.5e-13 48.4 1.1 8.7e-13 48.2 1.1 1.2 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KXL51465.1 - 0.00017 21.8 0.3 0.00036 20.7 0.0 1.7 2 0 0 2 2 2 1 H2C2 zinc finger Nup88 PF10168.9 KXL51465.1 - 0.06 11.2 0.1 0.062 11.1 0.1 1.0 1 0 0 1 1 1 0 Nuclear pore component Peptidase_S8 PF00082.22 KXL51467.1 - 9.9e-36 123.5 11.7 1.5e-35 122.9 11.7 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KXL51467.1 - 2.7e-19 69.6 1.3 4.7e-19 68.8 0.3 2.0 2 0 0 2 2 2 1 Peptidase inhibitor I9 ATP-cone PF03477.16 KXL51467.1 - 0.19 12.3 1.4 0.48 11.0 0.4 2.1 2 0 0 2 2 2 0 ATP cone domain Beach PF02138.18 KXL51468.1 - 6.8e-120 399.6 0.0 1.2e-119 398.8 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 KXL51468.1 - 2.1e-10 40.6 0.0 6.4e-10 39.0 0.0 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 KXL51468.1 - 8e-08 32.6 0.0 1.9e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 KXL51468.1 - 0.0025 18.6 1.2 3.7 8.6 0.1 4.3 3 0 0 3 3 3 1 WD domain, G-beta repeat FAM76 PF16046.5 KXL51469.1 - 3.2 7.0 6.7 4.2 6.6 6.7 1.1 1 0 0 1 1 1 0 FAM76 protein DUF2293 PF10056.9 KXL51472.1 - 3.8e-23 81.5 0.2 6.2e-23 80.9 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) PAF-AH_p_II PF03403.13 KXL51473.1 - 5.3e-24 84.4 0.0 8.5e-20 70.6 0.0 3.1 2 1 1 3 3 3 3 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KXL51473.1 - 3.2e-05 23.0 0.0 4.9e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KXL51473.1 - 0.002 17.2 0.0 0.0029 16.7 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.8 KXL51473.1 - 0.045 13.0 0.0 0.067 12.4 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 RRM_1 PF00076.22 KXL51474.1 - 4.2e-16 58.5 0.3 1.1e-07 31.5 0.1 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXL51474.1 - 0.1 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif ZapD PF07072.11 KXL51474.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Cell division protein SapB_1 PF05184.15 KXL51474.1 - 0.14 12.2 0.2 0.26 11.4 0.2 1.5 1 0 0 1 1 1 0 Saposin-like type B, region 1 Ammonium_transp PF00909.21 KXL51475.1 - 4e-52 177.2 26.6 7.9e-41 140.1 12.8 3.3 1 1 2 3 3 3 3 Ammonium Transporter Family adh_short_C2 PF13561.6 KXL51476.1 - 6.6e-51 173.1 0.0 8.1e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL51476.1 - 6.7e-45 152.9 0.2 7.9e-45 152.7 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL51476.1 - 2.1e-11 44.1 0.0 2.9e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXL51476.1 - 0.00051 19.3 0.0 0.00061 19.0 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KXL51476.1 - 0.0024 17.4 0.0 0.0041 16.6 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.12 KXL51476.1 - 0.092 13.4 0.0 0.48 11.1 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain MFS_1 PF07690.16 KXL51477.1 - 5.1e-38 130.9 31.8 5.1e-38 130.9 31.8 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Nop PF01798.18 KXL51478.1 - 3.5e-71 239.3 0.4 5.5e-71 238.7 0.0 1.5 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 KXL51478.1 - 2.1e-47 160.9 0.7 6.8e-47 159.3 0.7 1.9 1 1 0 1 1 1 1 Prp31 C terminal domain RRN3 PF05327.11 KXL51478.1 - 2.4 6.6 6.8 3.7 6.0 6.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 HAT PF02184.16 KXL51479.1 - 5.8e-21 74.1 76.9 7.6e-14 51.4 7.7 13.4 14 0 0 14 14 14 4 HAT (Half-A-TPR) repeat TPR_19 PF14559.6 KXL51479.1 - 5.1e-18 65.3 4.8 4.6e-06 27.1 0.0 6.9 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXL51479.1 - 2.4e-15 55.9 36.9 0.0029 18.3 2.4 13.1 6 4 8 14 14 14 4 Tetratricopeptide repeat Suf PF05843.14 KXL51479.1 - 1.7e-12 47.9 16.7 5.6e-05 23.3 0.7 5.4 5 1 1 6 6 6 3 Suppressor of forked protein (Suf) TPR_8 PF13181.6 KXL51479.1 - 2.3e-06 27.4 3.6 22 5.6 0.0 7.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 KXL51479.1 - 2.7e-06 27.4 4.2 0.039 14.3 0.1 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXL51479.1 - 1.1e-05 25.2 20.3 1.8 8.9 0.1 8.9 10 0 0 10 10 10 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXL51479.1 - 0.00067 19.7 2.7 11 6.2 0.2 4.6 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat U3_assoc_6 PF08640.11 KXL51479.1 - 0.003 17.6 18.1 0.14 12.2 1.9 6.6 6 1 0 6 6 6 2 U3 small nucleolar RNA-associated protein 6 TPR_16 PF13432.6 KXL51479.1 - 0.0035 17.9 25.1 0.0042 17.7 0.6 7.4 7 2 1 9 9 9 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXL51479.1 - 0.0077 16.4 2.7 1.5 9.1 0.0 4.5 5 0 0 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 Mad3_BUB1_I PF08311.12 KXL51479.1 - 0.033 14.2 19.1 0.12 12.4 0.7 6.6 5 3 0 5 5 5 0 Mad3/BUB1 homology region 1 DUF4880 PF16220.5 KXL51479.1 - 0.2 11.5 4.6 0.69 9.8 0.1 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4880) TPR_9 PF13371.6 KXL51479.1 - 0.59 10.3 16.0 0.76 10.0 2.2 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXL51479.1 - 1.7 9.4 21.2 12 6.8 0.0 7.4 8 0 0 8 8 7 0 Tetratricopeptide repeat Fungal_trans_2 PF11951.8 KXL51480.1 - 2.7e-19 69.2 0.1 5.8e-18 64.9 0.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL51480.1 - 0.16 12.1 1.0 0.34 11.1 1.0 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 KXL51481.1 - 5e-66 222.6 0.0 6.2e-66 222.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXL51481.1 - 3.1e-52 176.9 0.4 3.8e-52 176.6 0.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXL51481.1 - 1e-11 45.1 0.1 2.2e-11 44.0 0.1 1.5 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KXL51481.1 - 5.3e-06 26.7 0.1 1e-05 25.8 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KXL51481.1 - 1.4e-05 24.7 0.3 3.1e-05 23.6 0.3 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KXL51481.1 - 0.0001 22.2 0.2 0.00016 21.6 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KXL51481.1 - 0.0019 17.2 0.5 0.0031 16.6 0.5 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 KXL51481.1 - 0.0036 17.8 0.2 0.0077 16.8 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 KXL51481.1 - 0.0066 16.7 0.1 0.013 15.8 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain Polysacc_synt_2 PF02719.15 KXL51481.1 - 0.037 13.2 0.2 0.074 12.2 0.1 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein AdoHcyase_NAD PF00670.21 KXL51481.1 - 0.071 13.2 2.9 0.14 12.2 2.6 1.6 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Dak1 PF02733.17 KXL51482.1 - 7.6e-100 333.8 0.0 1.5e-99 332.8 0.0 1.5 2 0 0 2 2 2 1 Dak1 domain Dak2 PF02734.17 KXL51482.1 - 5.5e-36 124.1 1.6 8.9e-36 123.4 1.6 1.3 1 0 0 1 1 1 1 DAK2 domain F_bP_aldolase PF01116.20 KXL51483.1 - 2.4e-80 270.0 0.0 2.7e-80 269.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II STAS PF01740.21 KXL51483.1 - 0.18 11.4 0.0 0.47 10.1 0.0 1.7 2 0 0 2 2 2 0 STAS domain NPR3 PF03666.13 KXL51484.1 - 2.2e-79 267.5 3.8 5.7e-44 150.7 1.1 3.3 1 1 2 3 3 3 3 Nitrogen Permease regulator of amino acid transport activity 3 TORC_M PF12885.7 KXL51484.1 - 0.054 13.4 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain Mito_carr PF00153.27 KXL51485.1 - 2.1e-68 226.3 1.0 1.1e-24 86.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Antimicrobial_8 PF08103.11 KXL51485.1 - 0.062 13.5 0.3 17 5.8 0.0 2.6 2 0 0 2 2 2 0 Uperin family GMC_oxred_N PF00732.19 KXL51486.1 - 1.6e-29 103.2 0.3 9.5e-28 97.4 0.1 2.6 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXL51486.1 - 1.1e-17 64.8 0.3 3e-17 63.5 0.1 1.9 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 KXL51486.1 - 0.14 11.4 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Adeno_E3 PF06040.11 KXL51486.1 - 0.17 12.1 0.0 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 Adenovirus E3 protein SNF2_N PF00176.23 KXL51487.1 - 5.1e-61 206.3 1.4 8.4e-61 205.6 1.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXL51487.1 - 5e-17 62.3 0.0 1.6e-16 60.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXL51487.1 - 2.1e-10 40.8 0.6 1.5e-09 38.1 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KXL51487.1 - 8.8e-06 25.6 0.0 2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase NDUF_B8 PF05821.11 KXL51488.1 - 7e-07 29.3 0.1 7e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Clr2_transil PF16761.5 KXL51489.1 - 2.9e-15 56.9 0.1 6.3e-15 55.8 0.1 1.6 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 KXL51489.1 - 1.7e-14 54.9 0.1 1e-13 52.3 0.0 2.4 2 1 0 2 2 2 1 Transcription-silencing protein Clr2 BSP_II PF05432.11 KXL51489.1 - 9.3 5.8 14.2 17 5.0 14.2 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Abhydrolase_3 PF07859.13 KXL51490.1 - 3e-12 46.8 0.0 7.6e-12 45.5 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXL51490.1 - 1.6e-08 34.3 0.2 0.0011 18.4 0.0 2.2 1 1 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 KXL51490.1 - 1e-06 27.9 0.0 1.7e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KXL51490.1 - 0.00036 19.6 0.0 0.00054 19.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase COesterase PF00135.28 KXL51490.1 - 0.0013 17.7 0.0 0.0038 16.2 0.0 1.6 2 0 0 2 2 2 1 Carboxylesterase family Hydrolase_4 PF12146.8 KXL51490.1 - 0.0031 16.8 0.0 0.0053 16.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 AXE1 PF05448.12 KXL51490.1 - 0.0059 15.3 0.0 0.046 12.4 0.0 2.0 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) DUF2953 PF11167.8 KXL51490.1 - 0.051 13.7 0.0 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) Say1_Mug180 PF10340.9 KXL51490.1 - 0.11 11.4 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Steryl acetyl hydrolase SnoaL_4 PF13577.6 KXL51491.1 - 4.7e-10 39.7 0.0 5.4e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Nitroreductase PF00881.24 KXL51492.1 - 1.7e-16 60.7 0.0 2.1e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family MFS_1 PF07690.16 KXL51493.1 - 9.1e-41 139.9 33.2 9.1e-41 139.9 33.2 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXL51493.1 - 9.8e-12 44.5 19.3 4.8e-11 42.2 19.3 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KXL51493.1 - 2.8e-06 26.0 1.5 2.8e-06 26.0 1.5 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KXL51493.1 - 1.8e-05 24.2 1.3 1.8e-05 24.2 1.3 1.9 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Abhydrolase_1 PF00561.20 KXL51495.1 - 7.6e-17 61.8 0.2 9.1e-16 58.3 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXL51495.1 - 6.9e-16 59.5 1.8 5.8e-14 53.2 1.8 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXL51495.1 - 4.4e-09 35.9 0.0 8.8e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KXL51495.1 - 0.00069 19.3 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 KXL51495.1 - 0.021 13.8 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme AXE1 PF05448.12 KXL51495.1 - 0.08 11.6 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 KXL51495.1 - 0.099 12.1 0.1 0.5 9.8 0.1 2.1 2 1 0 2 2 2 0 Prolyl oligopeptidase family CHB_HEX PF03173.13 KXL51495.1 - 0.1 12.2 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 Putative carbohydrate binding domain RIO1 PF01163.22 KXL51496.1 - 1.3e-69 233.6 0.0 1.3e-69 233.6 0.0 2.0 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 KXL51496.1 - 0.0054 16.7 0.3 2.1 8.2 0.0 2.6 3 0 0 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 KXL51496.1 - 0.0066 15.8 0.1 0.039 13.3 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3368 PF11848.8 KXL51497.1 - 0.12 12.1 0.1 0.29 10.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3368) APG17 PF04108.12 KXL51498.1 - 1.1e-105 354.0 11.1 1.3e-105 353.8 11.1 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 DUF1664 PF07889.12 KXL51498.1 - 0.0098 15.9 7.7 2.3 8.3 0.1 4.3 3 1 1 4 4 4 2 Protein of unknown function (DUF1664) Dynactin_p22 PF07426.11 KXL51498.1 - 0.019 14.8 6.9 0.14 12.0 0.3 3.6 2 2 2 4 4 4 0 Dynactin subunit p22 VSG_B PF13206.6 KXL51498.1 - 0.1 11.8 1.1 0.19 11.0 1.1 1.4 1 0 0 1 1 1 0 Trypanosomal VSG domain Atg14 PF10186.9 KXL51498.1 - 0.12 11.4 2.4 0.24 10.5 2.4 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fez1 PF06818.15 KXL51498.1 - 0.31 11.5 13.2 4.2 7.8 2.4 3.3 1 1 2 3 3 3 0 Fez1 SPATA1_C PF15743.5 KXL51498.1 - 0.49 10.5 6.5 0.27 11.3 3.0 2.5 2 1 0 2 2 2 0 Spermatogenesis-associated C-terminus DUF1804 PF08822.11 KXL51498.1 - 0.77 9.7 8.7 0.39 10.7 2.3 3.2 3 2 0 3 3 3 0 Protein of unknown function (DUF1804) DUF745 PF05335.13 KXL51498.1 - 0.91 9.2 10.9 0.13 12.0 2.8 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF745) Sec34 PF04136.15 KXL51498.1 - 1.1 9.2 9.2 10 6.0 1.2 3.4 2 1 0 3 3 3 0 Sec34-like family DASH_Dad2 PF08654.10 KXL51498.1 - 1.2 9.5 6.6 10 6.6 0.1 3.5 4 0 0 4 4 4 0 DASH complex subunit Dad2 DUF4600 PF15372.6 KXL51498.1 - 1.5 9.3 12.9 0.67 10.4 2.9 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4600) DUF4201 PF13870.6 KXL51498.1 - 1.6 8.4 11.3 6.3 6.5 8.2 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4201) Nup54 PF13874.6 KXL51498.1 - 2.1 8.4 7.5 65 3.6 0.0 3.0 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 CREPT PF16566.5 KXL51498.1 - 2.7 8.2 13.4 0.64 10.2 2.0 3.2 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour WD40 PF00400.32 KXL51499.1 - 3e-48 160.8 14.0 1.2e-06 29.1 0.0 8.8 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 KXL51499.1 - 8.2e-12 44.8 0.2 1.6e-11 43.9 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXL51499.1 - 5.2e-10 39.0 0.1 1.3e-09 37.7 0.1 1.8 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 KXL51499.1 - 6.7e-07 28.3 8.1 1.1 7.9 0.0 5.4 4 2 2 6 6 6 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KXL51499.1 - 3.2e-06 27.4 0.5 0.16 12.2 0.0 4.6 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KXL51499.1 - 2.9e-05 23.6 0.0 4.3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 WD40-like domain F-box_4 PF15966.5 KXL51499.1 - 0.00092 19.1 0.0 0.0027 17.6 0.0 1.8 1 0 0 1 1 1 1 F-box SUIM_assoc PF16619.5 KXL51499.1 - 0.018 15.1 6.1 0.056 13.5 6.1 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 KXL51499.1 - 0.24 11.0 6.4 0.44 10.1 6.4 1.3 1 0 0 1 1 1 0 Spt20 family DIOX_N PF14226.6 KXL51500.1 - 0.00034 21.4 0.0 0.00067 20.4 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Synapsin_N PF10581.9 KXL51500.1 - 0.03 14.2 0.3 0.074 13.0 0.0 1.8 2 0 0 2 2 2 0 Synapsin N-terminal 2OG-FeII_Oxy PF03171.20 KXL51500.1 - 0.13 12.8 0.0 0.47 11.0 0.0 1.9 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily DUF4804 PF16062.5 KXL51501.1 - 2.9e-86 290.1 0.0 2.1e-50 171.9 0.0 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4804) TruB_C PF09142.11 KXL51501.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal SLATT_1 PF18181.1 KXL51503.1 - 0.01 15.8 0.0 0.29 11.0 0.0 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 DUF1616 PF07760.11 KXL51503.1 - 0.13 11.7 0.0 0.53 9.6 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1616) DHHC PF01529.20 KXL51504.1 - 8.2e-34 116.6 1.8 8.2e-34 116.6 1.8 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase Myb_DNA-bind_2 PF08914.11 KXL51505.1 - 1.2e-16 60.6 0.3 4.8e-16 58.7 0.3 2.1 1 0 0 1 1 1 1 Rap1 Myb domain Rap1_C PF11626.8 KXL51505.1 - 1.3e-14 54.0 0.5 5.7e-13 48.8 0.1 2.8 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain BRCT_2 PF16589.5 KXL51505.1 - 1.3e-07 31.9 0.0 4.2e-07 30.3 0.0 2.0 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Rap1-DNA-bind PF09197.10 KXL51505.1 - 6.1e-05 23.6 2.6 0.0011 19.6 0.1 3.5 2 2 1 3 3 3 1 Rap1, DNA-binding BRCT PF00533.26 KXL51505.1 - 0.019 15.3 0.0 0.051 14.0 0.0 1.7 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Abhydrolase_1 PF00561.20 KXL51506.1 - 4.3e-21 75.7 0.1 2.6e-17 63.3 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXL51506.1 - 2.6e-16 60.9 0.0 3.2e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXL51506.1 - 1.4e-05 24.5 0.0 0.00024 20.4 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 KXL51506.1 - 0.23 10.1 0.0 0.32 9.6 0.0 1.2 1 0 0 1 1 1 0 Ndr family HTH_psq PF05225.16 KXL51507.1 - 2.3e-08 33.6 0.1 3e-08 33.2 0.1 1.1 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_ISL3 PF13542.6 KXL51507.1 - 0.0052 16.2 0.0 0.0069 15.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 NUMOD1 PF07453.13 KXL51507.1 - 0.015 15.5 0.3 0.018 15.3 0.3 1.2 1 0 0 1 1 1 0 NUMOD1 domain HTH_7 PF02796.15 KXL51507.1 - 0.015 15.3 0.4 0.022 14.9 0.4 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_30 PF13556.6 KXL51507.1 - 0.056 13.3 0.0 0.086 12.6 0.0 1.2 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_DeoR PF08220.12 KXL51507.1 - 0.057 13.2 0.0 0.081 12.7 0.0 1.2 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain RWP-RK PF02042.15 KXL51507.1 - 0.057 13.4 0.0 0.078 13.0 0.0 1.3 1 0 0 1 1 1 0 RWP-RK domain Tet_res_leader PF08050.12 KXL51507.1 - 0.058 13.2 0.0 0.095 12.5 0.0 1.4 1 0 0 1 1 1 0 Tetracycline resistance leader peptide HTH_28 PF13518.6 KXL51507.1 - 0.082 13.0 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_1 PF00126.27 KXL51507.1 - 0.1 12.6 0.2 0.13 12.2 0.2 1.2 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Lyase_1 PF00206.20 KXL51508.1 - 3.1e-48 164.8 0.0 2.3e-47 161.9 0.0 2.1 2 1 0 2 2 2 1 Lyase ADSL_C PF10397.9 KXL51508.1 - 9.8e-19 67.7 0.1 6.5e-18 65.0 0.0 2.3 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus Fungal_trans_2 PF11951.8 KXL51509.1 - 1.5e-05 24.0 0.6 2.1e-05 23.5 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2520 PF10728.9 KXL51509.1 - 0.082 12.7 0.1 7.5 6.3 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2520) AA_permease_2 PF13520.6 KXL51510.1 - 5.7e-48 163.8 46.5 7.8e-48 163.3 46.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXL51510.1 - 1.1e-21 77.0 38.2 1.6e-21 76.5 38.2 1.1 1 0 0 1 1 1 1 Amino acid permease NAD_binding_4 PF07993.12 KXL51511.1 - 2.6e-33 115.3 0.0 4e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KXL51511.1 - 3.6e-29 101.6 0.0 8.7e-29 100.4 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KXL51511.1 - 1.1e-11 44.6 0.0 3e-11 43.3 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXL51511.1 - 4.1e-06 26.4 0.0 2.8e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase PP-binding PF00550.25 KXL51511.1 - 5.3e-05 23.5 0.0 0.00013 22.2 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.17 KXL51511.1 - 0.018 14.2 0.3 0.075 12.1 0.1 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain NmrA PF05368.13 KXL51511.1 - 0.063 12.8 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family 3Beta_HSD PF01073.19 KXL51511.1 - 0.072 12.1 0.0 0.21 10.6 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Fer4_23 PF18009.1 KXL51511.1 - 0.081 13.4 0.2 1 9.8 0.0 2.3 2 0 0 2 2 2 0 4Fe-4S iron-sulfur cluster binding domain FMO-like PF00743.19 KXL51512.1 - 4.2e-19 68.4 0.1 3.7e-16 58.6 0.0 2.7 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXL51512.1 - 1.3e-07 31.8 0.0 3.9e-07 30.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXL51512.1 - 0.00088 18.5 0.0 0.048 12.8 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXL51512.1 - 0.0025 17.8 0.0 0.46 10.5 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KXL51512.1 - 0.012 14.9 0.0 0.38 9.9 0.0 2.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXL51512.1 - 0.018 14.3 0.0 0.31 10.2 0.0 2.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXL51512.1 - 0.18 11.1 0.7 23 4.2 0.0 3.3 4 0 0 4 4 4 0 Alanine dehydrogenase/PNT, C-terminal domain CBFD_NFYB_HMF PF00808.23 KXL51514.1 - 7.4e-30 103.0 1.2 9.5e-30 102.7 1.2 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXL51514.1 - 3e-06 27.6 0.2 4.3e-06 27.1 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 KXL51514.1 - 0.00044 20.2 0.4 0.00065 19.7 0.0 1.5 2 0 0 2 2 2 1 Bromodomain associated TFIID-18kDa PF02269.16 KXL51514.1 - 0.00046 20.2 0.0 0.00068 19.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-T_C PF15511.6 KXL51514.1 - 0.00088 19.4 0.0 0.0011 19.1 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 KXL51514.1 - 0.011 16.3 0.2 0.029 14.9 0.0 1.7 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Prefoldin_2 PF01920.20 KXL51516.1 - 1.3e-23 83.0 6.4 1.5e-23 82.7 6.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF2205 PF10224.9 KXL51516.1 - 0.0015 18.5 10.4 0.0042 17.0 2.3 2.1 2 0 0 2 2 2 2 Short coiled-coil protein Rx_N PF18052.1 KXL51516.1 - 0.022 15.0 3.8 0.37 11.1 0.5 2.2 2 0 0 2 2 2 0 Rx N-terminal domain EAP30 PF04157.16 KXL51516.1 - 0.025 13.8 3.9 0.15 11.3 1.8 2.1 1 1 1 2 2 2 0 EAP30/Vps36 family ZapB PF06005.12 KXL51516.1 - 0.18 12.3 9.1 1.7 9.2 1.7 2.2 2 0 0 2 2 2 0 Cell division protein ZapB Activator-TraM PF11657.8 KXL51516.1 - 0.32 10.8 3.8 5.5 6.8 0.6 2.1 2 0 0 2 2 2 0 Transcriptional activator TraM FliE PF02049.18 KXL51516.1 - 0.39 10.9 6.9 1 9.5 2.1 2.1 2 0 0 2 2 2 0 Flagellar hook-basal body complex protein FliE SLATT_1 PF18181.1 KXL51516.1 - 0.97 9.4 4.9 0.53 10.2 0.8 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 SlyX PF04102.12 KXL51516.1 - 3.4 8.4 7.2 4.5 8.0 0.4 2.3 2 0 0 2 2 2 0 SlyX Cmc1 PF08583.10 KXL51517.1 - 6.7e-20 70.9 4.4 7.6e-20 70.7 4.4 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Latarcin PF10279.9 KXL51517.1 - 0.037 14.4 0.8 0.045 14.2 0.8 1.1 1 0 0 1 1 1 0 Latarcin precursor DUF3128 PF11326.8 KXL51517.1 - 0.29 11.5 4.0 0.84 10.0 4.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) CCDC84 PF14968.6 KXL51519.1 - 0.17 11.5 0.1 0.27 10.8 0.1 1.2 1 0 0 1 1 1 0 Coiled coil protein 84 FAD_binding_3 PF01494.19 KXL51520.1 - 3.7e-19 69.2 0.0 1.1e-11 44.6 0.1 2.5 2 1 0 2 2 2 2 FAD binding domain SE PF08491.10 KXL51520.1 - 0.00014 21.0 0.0 0.00021 20.4 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.12 KXL51520.1 - 0.00099 18.3 0.0 0.91 8.5 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein K_oxygenase PF13434.6 KXL51520.1 - 0.021 14.0 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXL51520.1 - 0.029 14.3 0.0 0.069 13.1 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXL51520.1 - 0.054 13.7 0.0 0.17 12.1 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF4336 PF14234.6 KXL51521.1 - 4.6e-14 52.3 0.0 7.8e-10 38.4 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) RNA_pol_A_bac PF01000.26 KXL51522.1 - 5e-23 81.6 0.0 5.6e-22 78.2 0.0 2.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KXL51522.1 - 1.8e-19 68.9 0.0 2.5e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_49kDa PF00346.19 KXL51523.1 - 7.3e-124 412.2 0.0 1.1e-123 411.7 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 KXL51523.1 - 0.0044 16.0 0.0 0.0066 15.4 0.0 1.3 1 0 0 1 1 1 1 Nickel-dependent hydrogenase DUF2401 PF10287.9 KXL51524.1 - 4.1e-65 219.6 2.0 5.8e-65 219.1 2.0 1.2 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 KXL51524.1 - 2.1e-20 72.9 0.0 5.6e-20 71.5 0.0 1.8 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) SNARE_assoc PF09335.11 KXL51526.1 - 3.8e-14 53.2 6.3 5.4e-14 52.7 2.7 2.5 3 0 0 3 3 3 1 SNARE associated Golgi protein HATPase_c PF02518.26 KXL51527.1 - 5.9e-32 110.5 1.2 2.2e-31 108.6 0.3 2.5 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 KXL51527.1 - 1.5e-22 79.7 0.5 7.8e-22 77.4 0.5 2.3 3 0 0 3 3 3 1 PAS fold Response_reg PF00072.24 KXL51527.1 - 3.1e-22 78.8 0.1 7.8e-22 77.6 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KXL51527.1 - 4e-20 71.6 1.5 1.2e-19 70.0 0.1 2.7 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 KXL51527.1 - 5.3e-15 55.6 0.0 1.4e-07 31.7 0.0 3.6 3 0 0 3 3 3 3 PAS domain PAS_4 PF08448.10 KXL51527.1 - 1.7e-13 50.8 0.4 2.3e-07 31.0 0.1 4.0 3 0 0 3 3 3 3 PAS fold PAS PF00989.25 KXL51527.1 - 7.1e-09 35.7 0.1 3.4e-05 23.8 0.0 3.4 3 0 0 3 3 3 2 PAS fold HATPase_c_3 PF13589.6 KXL51527.1 - 0.00035 20.4 0.0 0.0011 18.8 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_10 PF13596.6 KXL51527.1 - 0.00058 20.4 0.0 4.1 8.1 0.0 3.7 3 0 0 3 3 3 2 PAS domain WLM PF08325.10 KXL51528.1 - 6.9e-56 189.3 0.4 1.5e-55 188.2 0.0 1.6 2 0 0 2 2 2 1 WLM domain zf-RanBP PF00641.18 KXL51528.1 - 0.00029 20.1 3.5 0.00029 20.1 3.5 3.1 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DZR PF12773.7 KXL51528.1 - 0.086 12.9 10.4 0.28 11.3 10.6 1.7 1 1 0 1 1 1 0 Double zinc ribbon Tox-MPTase3 PF15639.6 KXL51528.1 - 0.17 11.8 0.6 5.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Metallopeptidase toxin 3 zinc_ribbon_15 PF17032.5 KXL51528.1 - 0.67 10.7 4.5 1.6 9.5 4.5 1.6 1 1 0 1 1 1 0 zinc-ribbon family Zf_RING PF16744.5 KXL51528.1 - 4.8 7.4 10.8 0.28 11.3 4.4 2.2 1 1 1 2 2 2 0 KIAA1045 RING finger C1_2 PF03107.16 KXL51528.1 - 6.1 7.3 7.0 28 5.1 0.4 2.7 2 0 0 2 2 2 0 C1 domain PX PF00787.24 KXL51529.1 - 5.6e-20 71.4 0.4 3.9e-19 68.7 0.1 2.4 2 1 0 2 2 2 1 PX domain Vps5 PF09325.10 KXL51529.1 - 1.2e-10 41.3 14.1 8.7e-08 32.0 14.1 2.2 1 1 0 1 1 1 1 Vps5 C terminal like BAR_3 PF16746.5 KXL51529.1 - 0.0018 18.0 5.5 0.013 15.3 0.4 2.2 2 0 0 2 2 2 1 BAR domain of APPL family BAR PF03114.18 KXL51529.1 - 0.0047 16.6 11.8 0.066 12.8 11.8 2.2 1 1 0 1 1 1 1 BAR domain GCN5L1 PF06320.13 KXL51529.1 - 0.013 15.6 2.2 1.3 9.2 0.1 2.8 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) ATG16 PF08614.11 KXL51529.1 - 0.023 14.9 0.2 0.023 14.9 0.2 2.5 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Sec34 PF04136.15 KXL51529.1 - 0.028 14.3 3.5 0.031 14.1 0.1 2.6 2 1 0 2 2 2 0 Sec34-like family BAR_3_WASP_bdg PF10456.9 KXL51529.1 - 0.076 12.5 3.1 0.24 10.8 0.3 2.3 1 1 0 2 2 2 0 WASP-binding domain of Sorting nexin protein WXG100 PF06013.12 KXL51529.1 - 0.095 12.9 5.7 1.2 9.4 0.2 3.7 3 1 0 3 3 3 0 Proteins of 100 residues with WXG APG6_N PF17675.1 KXL51529.1 - 0.19 12.2 15.6 0.14 12.7 0.7 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region Taxilin PF09728.9 KXL51529.1 - 0.24 10.5 13.0 0.66 9.1 13.0 1.7 1 1 0 1 1 1 0 Myosin-like coiled-coil protein Prefoldin PF02996.17 KXL51529.1 - 0.63 10.0 6.7 3.6 7.5 0.1 3.5 4 0 0 4 4 4 0 Prefoldin subunit DUF1664 PF07889.12 KXL51529.1 - 0.98 9.5 6.7 7.1 6.7 1.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4618 PF15397.6 KXL51529.1 - 1.5 8.2 6.3 9.7 5.5 6.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) TMPIT PF07851.13 KXL51529.1 - 1.9 7.6 4.0 6 6.0 0.7 2.4 2 1 0 2 2 2 0 TMPIT-like protein Occludin_ELL PF07303.13 KXL51529.1 - 2.1 9.1 4.8 2.4 8.9 0.1 2.9 2 1 1 3 3 3 0 Occludin homology domain Lectin_N PF03954.14 KXL51529.1 - 2.3 8.0 4.2 1.2 8.8 0.1 2.4 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain TerB PF05099.13 KXL51529.1 - 4.4 7.3 15.5 0.25 11.3 1.7 3.3 3 1 0 3 3 3 0 Tellurite resistance protein TerB ADIP PF11559.8 KXL51529.1 - 4.4 7.4 13.7 16 5.6 2.4 3.2 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Prefoldin_2 PF01920.20 KXL51529.1 - 9.2 6.3 11.3 20 5.2 0.1 3.2 3 0 0 3 3 3 0 Prefoldin subunit p450 PF00067.22 KXL51530.1 - 7.7e-55 186.5 0.0 1.1e-54 185.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 APG6_N PF17675.1 KXL51531.1 - 0.066 13.7 25.0 0.11 13.1 8.1 2.8 1 1 1 2 2 2 0 Apg6 coiled-coil region AAA_15 PF13175.6 KXL51531.1 - 0.24 11.1 3.8 0.36 10.5 3.8 1.3 1 0 0 1 1 1 0 AAA ATPase domain EzrA PF06160.12 KXL51531.1 - 0.45 8.6 15.2 2.2 6.3 15.2 1.9 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA DUF3958 PF13125.6 KXL51531.1 - 0.57 10.4 9.8 4.9 7.4 8.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) HALZ PF02183.18 KXL51531.1 - 0.86 9.9 5.0 0.29 11.4 0.2 2.6 3 0 0 3 3 2 0 Homeobox associated leucine zipper TSNAXIP1_N PF15739.5 KXL51531.1 - 1.2 9.6 12.4 0.03 14.7 3.7 2.5 2 1 0 2 2 2 0 Translin-associated factor X-interacting N-terminus Lectin_N PF03954.14 KXL51531.1 - 1.3 8.8 3.7 1.4 8.7 0.1 2.6 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain DUF4795 PF16043.5 KXL51531.1 - 2.1 7.9 20.3 6.2 6.4 20.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Prominin PF05478.11 KXL51531.1 - 5.2 4.9 4.9 3.4 5.5 3.1 1.5 1 1 0 1 1 1 0 Prominin DivIC PF04977.15 KXL51531.1 - 7.3 6.4 10.5 0.8 9.5 0.3 3.9 3 1 1 4 4 4 0 Septum formation initiator ADIP PF11559.8 KXL51531.1 - 7.4 6.6 16.7 3.8 7.6 2.2 2.7 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding LPP PF04728.13 KXL51531.1 - 8.9 6.8 10.6 1.1 9.7 0.7 3.7 4 0 0 4 4 3 0 Lipoprotein leucine-zipper DEAD PF00270.29 KXL51532.1 - 6.1e-46 156.4 0.9 9.9e-46 155.7 0.9 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXL51532.1 - 5.5e-19 68.5 1.8 8.4e-16 58.3 0.2 3.6 2 2 2 4 4 4 2 Helicase conserved C-terminal domain ResIII PF04851.15 KXL51532.1 - 2.6e-06 27.6 0.0 4e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KXL51532.1 - 0.00031 21.1 0.6 0.0029 17.9 0.3 2.2 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXL51532.1 - 0.00045 20.0 0.1 0.00084 19.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXL51532.1 - 0.0062 16.8 1.0 0.038 14.3 1.0 2.2 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.6 KXL51532.1 - 0.02 14.3 0.2 0.055 12.8 0.0 1.8 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit IL17R_D_N PF16742.5 KXL51532.1 - 0.076 13.1 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D fragilysinNterm PF16376.5 KXL51532.1 - 0.1 12.3 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of fragilysin Flavi_DEAD PF07652.14 KXL51532.1 - 0.11 12.4 0.1 0.51 10.3 0.1 2.1 1 1 0 1 1 1 0 Flavivirus DEAD domain Cupin_8 PF13621.6 KXL51533.1 - 9.3e-16 58.3 0.0 5.6e-14 52.5 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 KXL51533.1 - 5.5e-10 39.7 0.1 8.2e-09 35.9 0.1 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.7 KXL51533.1 - 2.4e-08 33.7 0.8 5e-08 32.7 0.8 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXL51533.1 - 0.00011 22.0 0.5 0.00011 22.0 0.5 2.1 3 0 0 3 3 3 1 F-box domain FAA_hydrolase PF01557.18 KXL51534.1 - 3.1e-50 170.9 0.0 3.7e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family tRNA-synt_2c PF01411.19 KXL51535.1 - 9.9e-221 734.0 0.2 9.9e-221 734.0 0.2 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KXL51535.1 - 7e-18 64.5 0.2 3.5e-17 62.2 0.3 2.2 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KXL51535.1 - 4.9e-11 43.2 7.2 4.9e-11 43.2 7.2 2.7 2 1 1 3 3 3 1 DHHA1 domain PDH PF02153.17 KXL51535.1 - 0.0012 17.9 0.5 0.0022 17.0 0.5 1.4 1 0 0 1 1 1 1 Prephenate dehydrogenase vWA-TerF-like PF10138.9 KXL51535.1 - 0.067 13.3 0.6 0.18 11.9 0.6 1.7 1 0 0 1 1 1 0 vWA found in TerF C terminus MukB_hinge PF16330.5 KXL51536.1 - 0.055 13.2 2.2 0.068 12.9 0.3 1.9 1 1 1 2 2 2 0 MukB hinge domain Glyco_hydro_16 PF00722.21 KXL51537.1 - 3.4e-06 26.7 0.0 9.3e-06 25.2 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 VMA21 PF09446.10 KXL51538.1 - 0.11 12.6 0.3 0.32 11.1 0.3 1.8 1 0 0 1 1 1 0 VMA21-like domain Epimerase PF01370.21 KXL51539.1 - 4.8e-18 65.5 0.0 7.2e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXL51539.1 - 9.5e-06 24.9 0.0 1.8e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KXL51539.1 - 0.00079 18.9 0.0 0.0053 16.2 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KXL51539.1 - 0.0079 16.1 0.0 0.03 14.2 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KXL51539.1 - 0.014 14.6 0.0 0.032 13.4 0.0 1.6 1 1 0 1 1 1 0 Male sterility protein 3Beta_HSD PF01073.19 KXL51539.1 - 0.015 14.3 0.0 0.17 10.9 0.0 2.2 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 KXL51539.1 - 0.11 12.7 0.0 0.36 11.1 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain BAH PF01426.18 KXL51540.1 - 6.8e-08 32.4 0.0 1.5e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H PF13771.6 KXL51540.1 - 0.017 15.4 0.2 0.1 12.9 0.0 2.0 2 0 0 2 2 2 0 PHD-like zinc-binding domain PHD PF00628.29 KXL51540.1 - 0.023 14.6 0.3 0.023 14.6 0.3 2.2 2 0 0 2 2 2 0 PHD-finger PH PF00169.29 KXL51541.1 - 7e-06 26.5 0.0 0.00044 20.7 0.0 2.4 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 KXL51541.1 - 0.0024 18.2 0.1 0.024 15.0 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain GTP_EFTU PF00009.27 KXL51542.1 - 2.3e-47 161.1 0.0 3.4e-47 160.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 KXL51542.1 - 8.8e-37 126.4 10.4 1.6e-36 125.6 10.4 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 KXL51542.1 - 4.4e-23 81.4 0.0 1.1e-22 80.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KXL51542.1 - 1.2e-18 66.9 0.0 3.1e-18 65.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KXL51542.1 - 2.1e-11 44.0 0.1 4.6e-11 43.0 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KXL51542.1 - 8.6e-07 29.0 0.1 2.5e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KXL51542.1 - 0.00012 22.2 0.0 0.00022 21.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KXL51542.1 - 0.01 15.3 0.1 0.081 12.4 0.1 2.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KXL51542.1 - 0.063 12.9 0.0 0.15 11.7 0.0 1.6 2 0 0 2 2 2 0 Ras family Dynamin_N PF00350.23 KXL51542.1 - 0.14 12.2 0.0 18 5.3 0.1 2.3 2 0 0 2 2 2 0 Dynamin family Roc PF08477.13 KXL51542.1 - 0.15 12.3 0.0 9.1 6.5 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Thiolase_N PF00108.23 KXL51544.1 - 3.9e-94 314.8 0.8 7.8e-94 313.8 0.2 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXL51544.1 - 9.5e-47 157.7 7.0 5.1e-46 155.3 1.2 3.0 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXL51544.1 - 4.6e-05 23.1 6.6 0.00043 19.9 5.0 2.8 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 KXL51544.1 - 0.003 16.3 0.3 0.0061 15.3 0.2 1.6 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) ACP_syn_III PF08545.10 KXL51544.1 - 0.0031 17.3 5.5 0.011 15.6 0.2 3.2 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.22 KXL51544.1 - 0.0075 16.3 0.9 14 5.7 0.0 3.8 4 0 0 4 4 4 1 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III_C PF08541.10 KXL51544.1 - 0.038 14.2 0.0 1.4 9.2 0.0 2.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF423 PF04241.15 KXL51545.1 - 1.3e-26 92.6 0.2 1.8e-26 92.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) DUF2721 PF11026.8 KXL51545.1 - 0.025 14.5 0.0 0.047 13.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2721) Vps8 PF12816.7 KXL51546.1 - 2.3e-67 226.4 0.4 6.1e-67 225.0 0.1 1.9 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 KXL51546.1 - 3.6e-08 33.4 0.0 0.012 15.5 0.0 2.8 2 0 0 2 2 2 2 Region in Clathrin and VPS zf-RING_2 PF13639.6 KXL51546.1 - 0.0015 18.9 0.3 0.0015 18.9 0.3 2.5 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KXL51546.1 - 0.0024 18.1 0.0 0.0066 16.7 0.0 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KXL51546.1 - 0.004 17.1 0.1 0.004 17.1 0.1 2.0 2 0 0 2 2 2 1 zinc-RING finger domain PHD PF00628.29 KXL51546.1 - 0.02 14.8 0.3 0.02 14.8 0.3 2.0 2 0 0 2 2 2 0 PHD-finger zf-RING_UBOX PF13445.6 KXL51546.1 - 0.031 14.3 0.1 0.089 12.8 0.1 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 KXL51546.1 - 0.094 12.8 0.2 0.094 12.8 0.2 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KXL51546.1 - 0.11 12.3 2.3 0.083 12.7 0.2 2.0 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXL51546.1 - 0.23 11.3 6.9 0.052 13.4 2.2 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF3752 PF12572.8 KXL51547.1 - 8.2e-41 140.0 12.8 8.2e-41 140.0 12.8 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) RCR PF12273.8 KXL51548.1 - 5.2e-11 43.2 0.6 8.8e-11 42.5 0.6 1.4 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red FeS_assembly_P PF01883.19 KXL51549.1 - 1.3e-09 38.1 0.0 4e-09 36.5 0.0 1.9 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein Zn_clus PF00172.18 KXL51550.1 - 9.2e-07 28.9 7.2 9.2e-07 28.9 7.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXL51550.1 - 9.8e-06 24.8 0.2 2.1e-05 23.7 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KXL51551.1 - 1.2e-15 57.3 15.3 1.4e-11 43.9 7.1 3.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DDE_1 PF03184.19 KXL51552.1 - 0.02 14.5 0.0 0.02 14.5 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease RGS PF00615.19 KXL51554.1 - 6.3e-11 42.6 0.0 8.2e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Pkinase PF00069.25 KXL51555.1 - 8.5e-51 172.8 0.0 2.3e-50 171.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXL51555.1 - 4.5e-26 91.7 0.0 1.3e-24 86.9 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KXL51555.1 - 5.5e-07 29.2 0.0 7.2e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXL51555.1 - 0.0019 18.2 0.1 0.014 15.4 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXL51555.1 - 0.0019 17.0 0.1 0.012 14.4 0.0 1.8 1 1 0 2 2 2 1 Fungal protein kinase cwf18 PF08315.12 KXL51556.1 - 1.5e-44 152.0 10.1 1.5e-44 152.0 10.1 1.8 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor Na_Ca_ex_C PF16494.5 KXL51556.1 - 2.9 8.3 7.9 4.9 7.6 0.1 2.9 3 0 0 3 3 3 0 C-terminal extension of sodium/calcium exchanger domain PPR_2 PF13041.6 KXL51557.1 - 4e-20 71.7 0.0 1.6e-11 44.2 0.0 4.1 3 1 1 4 4 4 3 PPR repeat family PPR_3 PF13812.6 KXL51557.1 - 7.7e-15 54.7 0.0 3.9e-09 36.5 0.0 2.6 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 KXL51557.1 - 1.9e-12 46.6 0.0 0.0002 21.0 0.0 4.3 4 0 0 4 4 4 2 PPR repeat PPR PF01535.20 KXL51557.1 - 8.9e-10 38.1 0.0 0.0001 22.3 0.0 3.9 3 0 0 3 3 3 2 PPR repeat PPR_long PF17177.4 KXL51557.1 - 3.2e-05 23.4 0.1 0.26 10.6 0.0 2.3 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP PMBR PF09373.10 KXL51557.1 - 0.16 12.2 0.0 0.46 10.7 0.0 1.8 1 0 0 1 1 1 0 Pseudomurein-binding repeat TPR_14 PF13428.6 KXL51557.1 - 0.31 12.0 2.5 40 5.4 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Pex19 PF04614.12 KXL51559.1 - 1.3e-66 224.9 9.5 1.3e-66 224.9 9.5 1.7 2 0 0 2 2 2 1 Pex19 protein family DUF445 PF04286.12 KXL51559.1 - 0.069 13.0 1.1 8.3 6.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF445) IR1-M PF12185.8 KXL51559.1 - 1.3 9.0 5.0 23 5.0 0.0 4.0 4 0 0 4 4 4 0 Nup358/RanBP2 E3 ligase domain GET2 PF08690.10 KXL51559.1 - 5 6.7 15.4 1.6 8.4 6.2 2.2 1 1 1 2 2 2 0 GET complex subunit GET2 UQ_con PF00179.26 KXL51560.1 - 2.3e-48 163.4 0.0 2.6e-48 163.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXL51560.1 - 4.9e-05 23.1 0.0 7.5e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KXL51560.1 - 0.014 15.7 0.4 0.037 14.3 0.4 1.8 1 1 0 1 1 1 0 RWD domain ABC1 PF03109.16 KXL51561.1 - 3.1e-34 117.7 0.0 5.6e-34 116.9 0.0 1.4 1 0 0 1 1 1 1 ABC1 family KRTDAP PF15200.6 KXL51562.1 - 0.083 12.7 0.1 0.32 10.8 0.0 1.9 2 0 0 2 2 2 0 Keratinocyte differentiation-associated DUF1738 PF08401.11 KXL51562.1 - 0.15 12.2 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1738) DIE2_ALG10 PF04922.12 KXL51563.1 - 3.3e-122 408.6 15.7 4e-122 408.3 15.7 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family Sld5 PF05916.11 KXL51564.1 - 3.7e-29 101.4 0.0 7.2e-29 100.4 0.0 1.5 1 0 0 1 1 1 1 GINS complex protein GGDEF_2 PF17853.1 KXL51564.1 - 0.047 14.0 0.1 0.12 12.6 0.1 1.7 1 1 0 1 1 1 0 GGDEF-like domain Ribosomal_L3 PF00297.22 KXL51565.1 - 9.2e-17 61.1 5.0 1.8e-14 53.5 3.3 2.2 1 1 1 2 2 2 2 Ribosomal protein L3 Hexapep PF00132.24 KXL51567.1 - 1.5e-10 40.4 15.3 7.9e-07 28.6 3.4 3.8 3 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KXL51567.1 - 1.8e-09 37.2 15.1 8e-07 28.7 4.0 3.7 4 0 0 4 4 4 3 Hexapeptide repeat of succinyl-transferase Zn_clus PF00172.18 KXL51567.1 - 4.1e-08 33.2 8.0 7.8e-08 32.3 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mac PF12464.8 KXL51567.1 - 0.00031 20.9 0.0 0.00089 19.4 0.0 1.8 1 0 0 1 1 1 1 Maltose acetyltransferase HTH_Tnp_Tc3_2 PF01498.18 KXL51568.1 - 0.063 13.5 0.1 0.083 13.2 0.1 1.1 1 0 0 1 1 1 0 Transposase EamA PF00892.20 KXL51569.1 - 4.8e-09 36.5 41.3 1e-06 29.0 7.3 2.7 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 KXL51569.1 - 0.003 16.8 16.3 0.0088 15.3 16.3 1.7 1 1 0 1 1 1 1 Nucleotide-sugar transporter CSG2 PF16965.5 KXL51569.1 - 0.0039 16.2 17.0 0.021 13.8 8.0 2.1 2 0 0 2 2 2 2 Ceramide synthase regulator Mpp10 PF04006.12 KXL51570.1 - 1.5e-107 360.6 41.7 6.6e-107 358.5 41.7 1.8 1 1 0 1 1 1 1 Mpp10 protein PRELI PF04707.14 KXL51571.1 - 2.3e-43 147.7 0.4 2.7e-43 147.5 0.4 1.0 1 0 0 1 1 1 1 PRELI-like family DUF1572 PF07609.11 KXL51571.1 - 0.0042 16.9 0.1 0.0066 16.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1572) DUF4715 PF15835.5 KXL51571.1 - 0.11 12.6 0.4 0.2 11.7 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4715) Kinesin_assoc PF16183.5 KXL51571.1 - 0.13 12.4 0.1 0.17 12.0 0.1 1.2 1 0 0 1 1 1 0 Kinesin-associated Tcf25 PF04910.14 KXL51572.1 - 2.6e-76 257.0 0.0 3.6e-76 256.5 0.0 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 DUF5536 PF17688.1 KXL51572.1 - 0.16 11.8 2.3 0.54 10.1 2.3 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5536) PNISR PF15996.5 KXL51572.1 - 3 8.1 13.7 5.2 7.3 13.7 1.4 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR DUF572 PF04502.13 KXL51572.1 - 3.1 7.3 12.4 5 6.7 12.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) peroxidase PF00141.23 KXL51573.1 - 3e-48 164.5 0.0 5.1e-48 163.8 0.0 1.4 1 0 0 1 1 1 1 Peroxidase AIF-MLS PF14962.6 KXL51573.1 - 0.13 12.2 1.7 0.23 11.4 1.7 1.4 1 0 0 1 1 1 0 Mitochondria Localisation Sequence SKG6 PF08693.10 KXL51574.1 - 0.0024 17.3 0.6 0.0049 16.3 0.6 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_2 PF07646.15 KXL51574.1 - 0.053 13.5 0.4 14 5.9 0.0 3.3 3 0 0 3 3 3 0 Kelch motif DUF347 PF03988.12 KXL51574.1 - 0.071 13.3 0.3 0.19 11.9 0.0 1.8 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) Mito_carr PF00153.27 KXL51575.1 - 2.3e-39 133.2 7.6 2.8e-17 62.4 0.1 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXL51575.1 - 0.017 14.3 0.2 0.46 9.6 0.0 2.5 2 1 0 2 2 2 0 Gammaproteobacterial serine protease Aa_trans PF01490.18 KXL51577.1 - 1.4e-37 129.4 29.0 1.6e-37 129.2 29.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ATG27 PF09451.10 KXL51577.1 - 0.11 12.3 0.2 0.11 12.3 0.2 1.6 2 0 0 2 2 2 0 Autophagy-related protein 27 DUF3671 PF12420.8 KXL51577.1 - 1.8 8.7 3.9 2.6 8.1 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function AhpC-TSA PF00578.21 KXL51578.1 - 7.9e-23 80.7 0.0 1.2e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXL51578.1 - 2.6e-13 49.9 0.2 3.6e-13 49.5 0.2 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KXL51578.1 - 0.027 14.6 0.0 0.097 12.8 0.0 1.7 1 1 1 2 2 2 0 AhpC/TSA antioxidant enzyme ACOX PF01756.19 KXL51579.1 - 4.3e-46 156.7 0.2 8.9e-46 155.7 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KXL51579.1 - 2.5e-26 92.7 0.1 6e-26 91.4 0.1 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KXL51579.1 - 6.8e-12 45.4 0.0 1.4e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KXL51579.1 - 1.4e-06 28.6 0.1 0.0083 16.3 0.0 2.4 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Rtt106 PF08512.12 KXL51580.1 - 3.8e-32 110.6 0.0 8e-32 109.5 0.0 1.6 1 0 0 1 1 1 1 Histone chaperone Rttp106-like PH_18 PF18469.1 KXL51580.1 - 7.9e-08 32.4 0.0 9.1e-07 28.9 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain AIP3 PF03915.13 KXL51585.1 - 2.7e-144 481.3 10.0 2.7e-144 481.3 10.0 1.6 2 0 0 2 2 2 1 Actin interacting protein 3 RE_MjaI PF09568.10 KXL51585.1 - 0.05 13.4 1.1 1.3 8.8 0.0 2.4 1 1 1 2 2 2 0 MjaI restriction endonuclease Lectin_N PF03954.14 KXL51585.1 - 0.13 12.0 3.5 0.18 11.5 0.1 3.1 3 1 0 3 3 3 0 Hepatic lectin, N-terminal domain Med11 PF10280.9 KXL51585.1 - 5.9 7.4 11.4 0.54 10.7 0.3 3.4 3 2 0 3 3 3 0 Mediator complex protein YtxH PF12732.7 KXL51585.1 - 6.1 7.4 6.2 1.1 9.9 0.1 2.9 3 0 0 3 3 3 0 YtxH-like protein LsmAD PF06741.13 KXL51586.1 - 3.4e-28 98.0 4.3 3.4e-28 98.0 4.3 2.7 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.6 KXL51586.1 - 2.2e-16 59.8 0.0 4.7e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain Ydc2-catalyt PF09159.10 KXL51587.1 - 3.1e-57 194.5 0.0 5.6e-57 193.6 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.13 KXL51587.1 - 0.00055 20.1 0.0 4.2 7.5 0.0 3.4 3 1 0 3 3 3 2 Poxvirus A22 protein SAP PF02037.27 KXL51587.1 - 0.023 14.5 0.0 0.055 13.2 0.0 1.7 1 0 0 1 1 1 0 SAP domain DUF1712 PF08217.11 KXL51588.1 - 5.5e-16 58.2 0.0 1.3e-13 50.3 0.0 3.4 2 2 0 2 2 2 2 Fungal domain of unknown function (DUF1712) Sugar_tr PF00083.24 KXL51589.1 - 3e-88 296.6 30.0 3.6e-88 296.4 30.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL51589.1 - 6.7e-18 64.7 38.5 2.8e-17 62.7 29.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sigma70_r4_2 PF08281.12 KXL51590.1 - 3.8e-05 23.3 0.1 6.3e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 KXL51590.1 - 4.4e-05 23.2 2.0 4.6e-05 23.1 0.2 2.0 2 0 0 2 2 2 1 Sigma-70 region 2 GerE PF00196.19 KXL51590.1 - 0.00057 19.4 0.1 0.00093 18.7 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_30 PF13556.6 KXL51590.1 - 0.0032 17.2 0.1 0.0067 16.2 0.1 1.5 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_1 PF00126.27 KXL51590.1 - 0.0032 17.4 0.3 0.0061 16.5 0.3 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Sigma70_r4 PF04545.16 KXL51590.1 - 0.0044 16.5 0.3 0.0079 15.7 0.3 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 KXL51590.1 - 0.019 14.7 0.2 0.05 13.4 0.2 1.7 1 0 0 1 1 1 0 Homeodomain-like domain AAA_12 PF13087.6 KXL51592.1 - 1.5e-23 83.5 0.0 2.1e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXL51592.1 - 6.5e-23 81.9 0.2 1.6e-21 77.3 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXL51592.1 - 1.4e-17 64.1 2.8 2.5e-09 37.1 0.0 3.9 4 1 0 4 4 4 2 AAA domain AAA_19 PF13245.6 KXL51592.1 - 3.7e-14 53.3 0.0 2e-12 47.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXL51592.1 - 1.8e-05 25.2 0.4 7e-05 23.3 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain UvrD_C_2 PF13538.6 KXL51592.1 - 8.3e-05 22.3 0.0 0.00022 21.0 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KXL51592.1 - 0.0013 18.6 0.0 1.6 8.4 0.0 2.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KXL51592.1 - 0.0015 18.8 0.0 0.04 14.2 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA PF00004.29 KXL51592.1 - 0.0024 18.3 0.0 0.0081 16.6 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KXL51592.1 - 0.0025 18.4 0.0 0.004 17.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 KXL51592.1 - 0.0031 17.0 0.0 0.076 12.5 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_33 PF13671.6 KXL51592.1 - 0.0071 16.5 0.4 0.058 13.6 0.1 2.5 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 KXL51592.1 - 0.0075 16.3 0.0 0.031 14.3 0.0 2.0 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit PIF1 PF05970.14 KXL51592.1 - 0.011 15.0 0.0 0.27 10.4 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase UvrD-helicase PF00580.21 KXL51592.1 - 0.013 15.0 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain TrwB_AAD_bind PF10412.9 KXL51592.1 - 0.021 13.8 0.0 0.06 12.2 0.0 1.7 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 KXL51592.1 - 0.024 14.2 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.13 KXL51592.1 - 0.025 13.8 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Helicase_RecD PF05127.14 KXL51592.1 - 0.028 14.3 0.1 5.7 6.7 0.0 2.6 2 0 0 2 2 2 0 Helicase AAA_5 PF07728.14 KXL51592.1 - 0.047 13.7 0.0 0.16 12.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KXL51592.1 - 0.066 12.8 1.7 0.11 12.0 0.4 2.1 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KXL51592.1 - 0.077 12.7 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXL51592.1 - 0.1 12.3 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.14 KXL51592.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 KXL51592.1 - 0.17 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 KXL51592.1 - 0.17 12.4 0.0 0.44 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain PsiE PF06146.12 KXL51593.1 - 0.00012 22.4 3.9 0.00017 21.9 3.9 1.3 1 0 0 1 1 1 1 Phosphate-starvation-inducible E AAA PF00004.29 KXL51594.1 - 3.2e-31 108.5 0.1 9.6e-31 106.9 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KXL51594.1 - 0.00026 20.3 0.0 0.00048 19.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 KXL51594.1 - 0.00033 21.1 1.5 0.0099 16.3 0.2 2.9 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KXL51594.1 - 0.0011 18.8 0.0 0.0031 17.3 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KXL51594.1 - 0.0014 18.7 0.0 0.0075 16.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KXL51594.1 - 0.0018 18.6 0.1 0.015 15.7 0.0 2.4 2 1 1 3 3 3 1 RNA helicase CPT PF07931.12 KXL51594.1 - 0.0028 17.5 0.0 0.0065 16.3 0.0 1.6 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_2 PF07724.14 KXL51594.1 - 0.014 15.5 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) PSCyt2 PF07583.11 KXL51594.1 - 0.019 14.9 0.3 0.052 13.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1549) AAA_3 PF07726.11 KXL51594.1 - 0.042 13.7 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 KXL51594.1 - 0.064 12.6 0.1 1.1 8.5 0.0 2.5 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_18 PF13238.6 KXL51594.1 - 0.072 13.6 0.0 0.23 12.0 0.0 2.0 3 0 0 3 3 1 0 AAA domain AAA_7 PF12775.7 KXL51594.1 - 0.086 12.3 0.0 0.24 10.9 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 KXL51594.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.6 KXL51594.1 - 0.12 12.5 0.1 0.74 10.0 0.0 2.2 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.22 KXL51594.1 - 0.18 11.4 0.1 8.5 5.9 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain YAcAr PF10686.9 KXL51595.1 - 2.5e-14 53.0 0.3 1.7e-13 50.3 0.2 2.3 2 0 0 2 2 2 1 YspA, cpYpsA-related SLOG family zf-C2H2_12 PF18658.1 KXL51595.1 - 0.05 13.2 0.0 0.084 12.5 0.0 1.3 1 0 0 1 1 1 0 Zinc-finger C2H2-type PLA2_B PF01735.18 KXL51597.1 - 8.4e-20 70.6 0.0 5.8e-19 67.9 0.0 2.0 1 1 0 1 1 1 1 Lysophospholipase catalytic domain HAD_2 PF13419.6 KXL51598.1 - 4.6e-20 72.5 0.0 9.4e-20 71.4 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXL51598.1 - 6e-10 39.8 0.0 0.00031 21.1 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXL51598.1 - 6.6e-05 23.4 0.0 0.0001 22.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXL51598.1 - 0.023 14.8 0.1 0.039 14.0 0.1 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like Vac_ImportDeg PF09783.9 KXL51599.1 - 4.5e-66 221.6 0.1 5.6e-66 221.3 0.1 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Mago_nashi PF02792.14 KXL51600.1 - 2e-73 245.2 0.3 2.2e-73 245.0 0.3 1.0 1 0 0 1 1 1 1 Mago nashi protein Adaptin_N PF01602.20 KXL51601.1 - 2e-91 307.1 6.7 3.5e-91 306.3 6.7 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 KXL51601.1 - 6.6e-58 194.6 0.4 1.4e-57 193.5 0.4 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 KXL51601.1 - 8.6e-55 184.2 0.0 2.9e-54 182.5 0.0 2.0 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 KXL51601.1 - 5.1e-14 52.6 3.3 1.2e-10 41.6 0.0 3.1 1 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXL51601.1 - 1e-09 38.6 1.0 0.014 15.8 0.0 4.6 2 2 2 4 4 4 4 HEAT repeats Coatomer_g_Cpla PF16381.5 KXL51601.1 - 0.00014 22.0 0.1 0.0049 17.0 0.0 2.8 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 KXL51601.1 - 0.0014 18.7 2.0 1.4 9.4 0.0 4.3 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 KXL51601.1 - 0.18 12.3 0.3 4.7 7.8 0.0 3.1 2 0 0 2 2 2 0 HEAT-like repeat CK_II_beta PF01214.18 KXL51603.1 - 4e-78 261.4 0.7 5.4e-78 261.0 0.7 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Uso1_p115_C PF04871.13 KXL51603.1 - 0.77 10.1 10.9 1.5 9.2 10.9 1.5 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF1115 PF06544.12 KXL51603.1 - 1.2 9.2 4.8 3.3 7.8 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1115) RIC1 PF07064.13 KXL51604.1 - 7.6e-85 284.3 0.0 1.1e-84 283.9 0.0 1.2 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 KXL51604.1 - 0.035 14.4 0.0 12 6.3 0.0 4.1 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain SCRG1 PF15224.6 KXL51604.1 - 0.038 14.1 0.0 2 8.6 0.0 2.3 2 0 0 2 2 2 0 Scrapie-responsive protein 1 Fungal_trans_2 PF11951.8 KXL51605.1 - 3e-06 26.3 0.2 7.8e-06 24.9 0.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain La PF05383.17 KXL51607.1 - 1.1e-15 57.4 0.5 2e-15 56.6 0.5 1.4 1 0 0 1 1 1 1 La domain SGTA_dimer PF16546.5 KXL51608.1 - 7.1e-24 83.4 0.0 1.2e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 KXL51608.1 - 8.2e-12 44.4 5.7 5e-06 26.1 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXL51608.1 - 2.1e-10 39.9 6.5 4.4e-05 23.3 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXL51608.1 - 3e-08 33.2 2.3 1.2e-05 24.9 1.2 2.7 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 KXL51608.1 - 1.4e-06 28.0 4.5 0.019 15.2 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXL51608.1 - 1.6e-06 28.7 6.1 0.0043 17.7 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXL51608.1 - 1e-05 25.6 0.7 0.0025 18.1 0.3 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat STI1 PF17830.1 KXL51608.1 - 8.5e-05 22.4 12.9 0.00044 20.1 9.4 2.4 2 0 0 2 2 2 1 STI1 domain TPR_19 PF14559.6 KXL51608.1 - 0.00023 21.6 1.1 0.0059 17.1 0.3 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXL51608.1 - 0.0003 21.4 3.0 0.82 10.7 0.2 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXL51608.1 - 0.0029 17.5 0.6 0.29 11.2 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXL51608.1 - 0.008 16.5 4.5 0.02 15.2 1.9 2.9 3 1 0 3 3 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXL51608.1 - 0.024 14.8 0.2 4.2 7.6 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat XPC-binding PF09280.11 KXL51608.1 - 0.24 11.2 4.5 0.59 9.9 4.5 1.7 1 0 0 1 1 1 0 XPC-binding domain TPR_6 PF13174.6 KXL51608.1 - 0.3 11.8 2.1 27 5.7 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Pre-PUA PF17832.1 KXL51609.1 - 2.3e-25 89.1 0.1 3.1e-25 88.7 0.1 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 KXL51609.1 - 6.6e-14 51.6 0.3 2.6e-13 49.7 0.3 1.9 1 1 0 1 1 1 1 PUA domain DUF1947 PF09183.10 KXL51609.1 - 0.049 13.9 0.2 0.1 12.9 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) SET PF00856.28 KXL51610.1 - 3.2e-21 76.5 0.1 9e-21 75.0 0.1 1.8 1 0 0 1 1 1 1 SET domain Pre-SET PF05033.16 KXL51610.1 - 2.3e-11 44.3 1.9 2.3e-11 44.3 1.9 2.5 2 1 0 2 2 2 1 Pre-SET motif Chromo PF00385.24 KXL51610.1 - 0.022 14.6 0.7 0.071 13.0 0.7 1.9 1 1 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Nop52 PF05997.12 KXL51611.1 - 1e-73 247.7 0.2 1.3e-73 247.3 0.2 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 HEAT_2 PF13646.6 KXL51611.1 - 0.044 14.2 0.3 5.6 7.4 0.0 2.4 2 0 0 2 2 2 0 HEAT repeats Prot_ATP_ID_OB PF16450.5 KXL51611.1 - 0.06 13.3 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain Mito_carr PF00153.27 KXL51612.1 - 4.2e-39 132.4 5.2 4.9e-15 55.2 0.7 4.4 3 2 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXL51612.1 - 0.0008 18.7 0.3 0.014 14.6 0.0 2.2 2 0 0 2 2 2 2 Gammaproteobacterial serine protease Fungal_trans_2 PF11951.8 KXL51613.1 - 1.4e-06 27.4 0.0 2.1e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXL51613.1 - 2.8e-06 27.3 7.2 2.8e-06 27.3 7.2 2.7 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tim54 PF11711.8 KXL51614.1 - 2e-144 481.0 3.1 2.3e-144 480.8 3.1 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 PAW PF04721.17 KXL51614.1 - 0.046 13.5 0.2 0.086 12.6 0.2 1.4 1 0 0 1 1 1 0 PNGase C-terminal domain, mannose-binding module PAW Ion_trans PF00520.31 KXL51616.1 - 4.7e-131 435.4 91.8 1e-47 162.5 9.7 4.9 4 1 0 4 4 4 4 Ion transport protein EF-hand_1 PF00036.32 KXL51616.1 - 0.00086 18.7 0.0 0.0031 16.9 0.0 2.1 1 0 0 1 1 1 1 EF hand GPHH PF16905.5 KXL51616.1 - 0.0016 18.2 0.0 0.004 16.9 0.0 1.7 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_6 PF13405.6 KXL51616.1 - 0.018 15.0 0.0 0.087 12.8 0.0 2.3 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 KXL51616.1 - 0.071 13.6 0.0 0.27 11.7 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair FAM176 PF14851.6 KXL51616.1 - 0.11 12.1 0.0 0.31 10.7 0.0 1.7 1 0 0 1 1 1 0 FAM176 family Ank_2 PF12796.7 KXL51617.1 - 2.1e-13 50.6 0.0 5e-06 27.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXL51617.1 - 7.7e-10 38.8 0.3 4.6e-07 30.0 0.0 3.1 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXL51617.1 - 1.7e-09 38.0 0.2 4e-06 27.3 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXL51617.1 - 7.3e-09 35.2 0.1 0.36 11.5 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 KXL51617.1 - 3.7e-06 27.1 0.1 0.0031 17.9 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat HTH_7 PF02796.15 KXL51617.1 - 0.029 14.4 0.1 0.075 13.1 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Asp_Glu_race PF01177.22 KXL51618.1 - 0.0045 16.9 0.0 0.0092 15.9 0.0 1.5 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase Ribosomal_L29 PF00831.23 KXL51619.1 - 1.5e-18 66.5 1.8 1.5e-18 66.5 1.8 1.9 2 0 0 2 2 2 1 Ribosomal L29 protein Snapin_Pallidin PF14712.6 KXL51619.1 - 0.04 14.3 3.3 0.04 14.3 3.3 1.8 2 0 0 2 2 2 0 Snapin/Pallidin CCDC-167 PF15188.6 KXL51619.1 - 3.8 7.9 8.6 11 6.4 0.9 2.5 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 PRKG1_interact PF15898.5 KXL51619.1 - 6.2 7.8 12.6 7.4e+02 1.1 12.6 2.3 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain V-SNARE_C PF12352.8 KXL51620.1 - 2.7e-13 50.0 0.5 2.7e-13 50.0 0.5 2.3 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Syntaxin-6_N PF09177.11 KXL51620.1 - 0.0015 19.1 2.4 0.0015 19.1 2.4 1.9 2 1 0 2 2 2 1 Syntaxin 6, N-terminal Interferon PF00143.19 KXL51620.1 - 0.037 14.2 2.1 0.076 13.2 2.1 1.6 1 1 0 1 1 1 0 Interferon alpha/beta domain Sec20 PF03908.13 KXL51620.1 - 0.17 11.8 1.8 6.2 6.8 0.0 3.0 2 1 1 3 3 3 0 Sec20 Sec34 PF04136.15 KXL51620.1 - 0.78 9.6 9.9 0.24 11.3 2.2 2.7 2 1 0 3 3 3 0 Sec34-like family ATP-synt_10 PF05176.14 KXL51621.1 - 2.1e-72 243.4 0.0 2.5e-72 243.2 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein TPR_2 PF07719.17 KXL51622.1 - 1.2e-09 37.5 0.0 6e-06 26.0 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXL51622.1 - 2.6e-08 33.4 0.0 2.3e-05 24.3 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXL51622.1 - 2e-07 31.2 8.4 0.2 12.6 0.0 5.2 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXL51622.1 - 2.5e-07 30.9 0.2 0.017 15.4 0.0 3.1 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXL51622.1 - 3.6e-06 27.4 7.5 0.081 13.4 0.2 4.1 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 KXL51622.1 - 1.4e-05 24.7 0.0 0.00032 20.4 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXL51622.1 - 1.8e-05 25.3 2.3 0.096 13.4 0.2 4.1 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXL51622.1 - 3.3e-05 23.6 3.0 0.0057 16.6 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KXL51622.1 - 0.00017 21.0 2.7 0.17 11.2 0.0 3.0 2 1 1 3 3 3 2 MalT-like TPR region TPR_11 PF13414.6 KXL51622.1 - 0.0017 18.0 0.0 0.078 12.7 0.0 2.8 2 0 0 2 2 2 1 TPR repeat TPR_6 PF13174.6 KXL51622.1 - 0.0031 18.0 6.7 0.15 12.7 0.0 4.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXL51622.1 - 0.014 15.5 1.5 0.37 11.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 KXL51622.1 - 0.076 12.5 1.2 18 4.9 0.0 3.5 2 1 0 2 2 2 0 SHNi-TPR TPR_10 PF13374.6 KXL51622.1 - 0.38 10.7 4.1 3.9 7.5 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 KXL51622.1 - 0.42 10.3 5.4 0.99 9.1 0.3 3.1 2 2 1 3 3 3 0 Tetratricopeptide repeat-like domain TPR_20 PF14561.6 KXL51622.1 - 4.4 7.7 11.3 5.4 7.4 0.2 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat HMG_box PF00505.19 KXL51623.1 - 1.7e-10 41.2 0.7 1.7e-10 41.2 0.7 1.4 2 0 0 2 2 2 1 HMG (high mobility group) box DUF4543 PF15076.6 KXL51623.1 - 0.011 15.9 0.1 0.018 15.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4543) HMG_box_2 PF09011.10 KXL51623.1 - 0.025 15.2 1.4 0.034 14.7 1.1 1.5 1 1 0 1 1 1 0 HMG-box domain RWD PF05773.22 KXL51624.1 - 3.5e-24 85.3 2.1 6.3e-24 84.5 2.1 1.4 1 0 0 1 1 1 1 RWD domain ketoacyl-synt PF00109.26 KXL51624.1 - 0.12 11.9 0.2 0.19 11.3 0.2 1.2 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain DFRP_C PF16543.5 KXL51624.1 - 3 8.4 14.3 4.2 7.9 12.4 2.1 1 1 1 2 2 2 0 DRG Family Regulatory Proteins, Tma46 RTA1 PF04479.13 KXL51625.1 - 1.3e-35 122.9 6.9 1.9e-35 122.3 6.9 1.2 1 0 0 1 1 1 1 RTA1 like protein Ninjurin PF04923.12 KXL51625.1 - 0.04 13.9 0.5 1.7 8.6 0.3 2.3 2 0 0 2 2 2 0 Ninjurin Transp_inhibit PF18791.1 KXL51625.1 - 0.31 10.6 1.5 1.6 8.3 0.1 2.6 3 0 0 3 3 3 0 Transport inhibitor response 1 protein domain Zn_clus PF00172.18 KXL51626.1 - 2.2e-08 34.1 9.4 4.1e-08 33.2 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXL51626.1 - 0.00047 19.1 0.8 0.001 18.0 0.8 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain PTCB-BRCT PF12738.7 KXL51627.1 - 4.1e-33 113.1 0.8 6.1e-21 74.1 0.4 4.0 4 0 0 4 4 4 3 twin BRCT domain BRCT_2 PF16589.5 KXL51627.1 - 2.7e-29 101.4 0.0 6e-07 29.8 0.1 6.2 6 0 0 6 6 6 5 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 KXL51627.1 - 1.8e-27 95.1 0.0 1.5e-23 82.6 0.0 3.8 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 KXL51627.1 - 1.2e-24 86.5 0.1 6.4e-08 32.9 0.1 6.0 6 0 0 6 6 6 4 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KXL51627.1 - 5.5e-07 29.8 0.1 1.2 9.4 0.1 4.4 4 0 0 4 4 4 3 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 KXL51627.1 - 2.6e-05 24.2 0.0 0.15 12.2 0.0 3.5 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain ESCRT-II PF05871.12 KXL51628.1 - 1.3e-49 168.0 0.1 3.9e-49 166.5 0.0 1.6 1 1 1 2 2 2 1 ESCRT-II complex subunit CN_hydrolase PF00795.22 KXL51629.1 - 1.7e-58 198.0 0.0 1.9e-58 197.8 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DHO_dh PF01180.21 KXL51630.1 - 2e-21 76.5 0.0 2.6e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 KXL51630.1 - 0.0048 16.3 1.5 0.009 15.4 1.4 1.5 2 0 0 2 2 2 1 Nitronate monooxygenase UQ_con PF00179.26 KXL51631.1 - 2.9e-31 108.0 0.0 4.5e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RNase_PH PF01138.21 KXL51634.1 - 1e-07 32.5 0.0 2.9e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 TMF_TATA_bd PF12325.8 KXL51635.1 - 2.1e-29 102.0 3.4 2.1e-29 102.0 3.4 7.0 3 2 4 7 7 7 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 KXL51635.1 - 1.8e-17 63.1 6.3 1.8e-17 63.1 6.3 7.7 7 1 0 7 7 7 1 TATA element modulatory factor 1 DNA binding ABC_tran_CTD PF16326.5 KXL51635.1 - 0.00094 19.4 1.9 0.00094 19.4 1.9 8.8 6 4 2 9 9 9 1 ABC transporter C-terminal domain ATG16 PF08614.11 KXL51635.1 - 0.0021 18.3 0.5 0.0021 18.3 0.5 6.4 3 2 2 5 5 5 2 Autophagy protein 16 (ATG16) DUF812 PF05667.11 KXL51635.1 - 0.048 12.5 54.0 0.085 11.7 0.0 4.4 2 1 2 4 4 4 0 Protein of unknown function (DUF812) BLOC1_2 PF10046.9 KXL51635.1 - 2.5 8.5 28.0 0.09 13.1 0.8 5.6 6 0 0 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mod_r PF07200.13 KXL51636.1 - 5.8e-25 88.1 0.1 6.9e-25 87.9 0.1 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Sugar_tr PF00083.24 KXL51637.1 - 5.7e-84 282.6 15.7 6.9e-84 282.3 15.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXL51637.1 - 1e-20 74.0 32.7 1.5e-13 50.5 11.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXL51637.1 - 6.7e-09 34.7 1.2 6.7e-09 34.7 1.2 1.9 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) Choline_kinase PF01633.20 KXL51638.1 - 7.1e-51 172.8 0.0 3.5e-49 167.3 0.0 2.1 2 0 0 2 2 2 2 Choline/ethanolamine kinase APH PF01636.23 KXL51638.1 - 9.6e-09 35.5 0.2 2.1e-08 34.4 0.1 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 KXL51638.1 - 0.004 16.5 0.0 0.0064 15.8 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Ribosomal_S11 PF00411.19 KXL51640.1 - 1.6e-07 31.7 0.6 3.8e-07 30.5 0.2 1.7 1 1 1 2 2 2 1 Ribosomal protein S11 BSP PF04450.12 KXL51640.1 - 0.045 13.5 0.0 0.14 12.0 0.0 1.7 1 1 1 2 2 2 0 Peptidase of plants and bacteria Tim44 PF04280.15 KXL51641.1 - 6.9e-37 126.8 0.0 1.4e-36 125.8 0.0 1.5 1 0 0 1 1 1 1 Tim44-like domain CHCH PF06747.13 KXL51642.1 - 4e-07 30.0 0.9 5.7e-07 29.5 0.9 1.2 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 KXL51642.1 - 0.0025 18.1 3.7 0.0076 16.5 3.7 1.7 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 KXL51642.1 - 0.04 13.9 1.9 0.056 13.5 1.9 1.2 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX17 PF05051.13 KXL51642.1 - 0.048 14.0 4.6 0.38 11.1 0.3 2.8 2 1 1 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.12 KXL51642.1 - 0.077 13.3 1.5 1.9 8.8 0.1 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Acidomyces_richmondensis-ASM157207v1/GCA_001572075.1_ASM157207v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Acidomyces_richmondensis-ASM157207v1/GCA_001572075.1_ASM157207v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Acidomyces_richmondensis-ASM157207v1/GCA_001572075.1_ASM157207v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Acidomyces_richmondensis-ASM157207v1/GCA_001572075.1_ASM157207v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 11:00:23 2019 # [ok]